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Search of human proteins with 217330610
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217330610 thyroid stimulating hormone receptor isoform 3
precursor [Homo sapiens]
(274 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217330610 thyroid stimulating hormone receptor isoform 3 prec... 555 e-158
gi|64085161 thyroid stimulating hormone receptor isoform 2 precu... 499 e-141
gi|64085121 thyroid stimulating hormone receptor isoform 1 precu... 470 e-133
gi|106067657 luteinizing hormone/choriogonadotropin receptor pre... 166 3e-41
gi|31657136 follicle stimulating hormone receptor isoform 2 prec... 128 6e-30
gi|31657138 follicle stimulating hormone receptor isoform 1 prec... 124 9e-29
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 57 2e-08
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 52 6e-07
gi|51317373 netrin-G1 ligand [Homo sapiens] 51 1e-06
gi|13194201 reticulon 4 receptor precursor [Homo sapiens] 50 2e-06
gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 48 1e-05
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens] 46 4e-05
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 45 7e-05
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 45 9e-05
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 44 2e-04
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 44 2e-04
gi|153251229 chondroadherin precursor [Homo sapiens] 43 3e-04
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 42 4e-04
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 42 6e-04
gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 41 0.001
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 41 0.001
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 41 0.001
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 41 0.001
gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens] 40 0.003
gi|45505137 podocan [Homo sapiens] 40 0.003
gi|88702793 slit-like 2 [Homo sapiens] 40 0.003
gi|14149694 retina specific protein PAL [Homo sapiens] 39 0.004
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 39 0.005
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 39 0.005
gi|4507531 toll-like receptor 3 [Homo sapiens] 39 0.006
>gi|217330610 thyroid stimulating hormone receptor isoform 3
precursor [Homo sapiens]
Length = 274
Score = 555 bits (1430), Expect = e-158
Identities = 274/274 (100%), Positives = 274/274 (100%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI 60
MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI
Sbjct: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI 60
Query: 61 ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD 120
ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD
Sbjct: 61 ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD 120
Query: 121 ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL 180
ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL
Sbjct: 121 ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL 180
Query: 181 TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAVSGK 240
TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAVSGK
Sbjct: 181 TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAVSGK 240
Query: 241 GFCKSLFSWLYRLPLGRKSLSFETQKAPRSSMPS 274
GFCKSLFSWLYRLPLGRKSLSFETQKAPRSSMPS
Sbjct: 241 GFCKSLFSWLYRLPLGRKSLSFETQKAPRSSMPS 274
>gi|64085161 thyroid stimulating hormone receptor isoform 2
precursor [Homo sapiens]
Length = 253
Score = 499 bits (1285), Expect = e-141
Identities = 253/274 (92%), Positives = 253/274 (92%), Gaps = 21/274 (7%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI 60
MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI
Sbjct: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI 60
Query: 61 ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD 120
ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD
Sbjct: 61 ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD 120
Query: 121 ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL 180
ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL
Sbjct: 121 ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL 180
Query: 181 TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAVSGK 240
TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL
Sbjct: 181 TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL--------- 231
Query: 241 GFCKSLFSWLYRLPLGRKSLSFETQKAPRSSMPS 274
LPLGRKSLSFETQKAPRSSMPS
Sbjct: 232 ------------LPLGRKSLSFETQKAPRSSMPS 253
>gi|64085121 thyroid stimulating hormone receptor isoform 1
precursor [Homo sapiens]
Length = 764
Score = 470 bits (1209), Expect = e-133
Identities = 245/272 (90%), Positives = 248/272 (91%), Gaps = 13/272 (4%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI 60
MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI
Sbjct: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLI 60
Query: 61 ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD 120
ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD
Sbjct: 61 ETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPD 120
Query: 121 ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL 180
ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL
Sbjct: 121 ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETL 180
Query: 181 TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL----VENVA 236
TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL A
Sbjct: 181 TLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTA 240
Query: 237 VSGKGF--CKSLF---SW-LYRLPLGRKSLSF 262
+ KG K L +W L +LPL SLSF
Sbjct: 241 LPSKGLEHLKELIARNTWTLKKLPL---SLSF 269
>gi|106067657 luteinizing hormone/choriogonadotropin receptor
precursor [Homo sapiens]
Length = 699
Score = 166 bits (419), Expect = 3e-41
Identities = 99/228 (43%), Positives = 139/228 (60%), Gaps = 12/228 (5%)
Query: 6 LLQLVLLLD--LPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETH 63
LL+L+LLL LPR L C P C C + R P L L
Sbjct: 10 LLKLLLLLQPPLPRALREALCPEP-CNCVPDGALRC--------PGPTAGLTRLSLAYLP 60
Query: 64 LRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALK 123
++ IPS AF L + +I +S +L+++E+++F NL ++ I I+NT+NL YI+P A
Sbjct: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
Query: 124 ELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLK 183
LP LK+L I NTG++ FPD+TKV+S++ FILEI DN ++T+IP NAFQG+ NE++TLK
Sbjct: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
Query: 184 LYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL 231
LY NGF VQ +AFNGT L ++ L +N +L + AF G +GP L
Sbjct: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGA-TGPKTL 227
>gi|31657136 follicle stimulating hormone receptor isoform 2
precursor [Homo sapiens]
Length = 633
Score = 128 bits (321), Expect = 6e-30
Identities = 88/263 (33%), Positives = 134/263 (50%), Gaps = 9/263 (3%)
Query: 6 LLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPS-LPPSTQTLKLIETHL 64
L+ L+ L L G GC C C F + IPS LP + L+ + T L
Sbjct: 5 LVSLLAFLSL-----GSGCHHRICHCSNRV-FLCQESKVTEIPSDLPRNAIELRFVLTKL 58
Query: 65 RTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKE 124
R I AFS ++ +I +S + L+ +E+ F NL K+ I I NL YI+P+A +
Sbjct: 59 RVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQN 118
Query: 125 LPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKL 184
LP L++L I NTG+K PD+ K++S +L+I DN + +I N+F GL E++ L L
Sbjct: 119 LPNLQYLLISNTGIKHLPDVHKIHSLQ-KVLLDIQDNINIHTIERNSFVGLSFESVILWL 177
Query: 185 YNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAVSGKGFCK 244
NG + AFNGT+LD + L+ N L + D F G SGP +L E + K +
Sbjct: 178 NKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGA-SGPVILSELHPICNKSILR 236
Query: 245 SLFSWLYRLPLGRKSLSFETQKA 267
++ + R SL+ + + +
Sbjct: 237 QEVDYMTQARGQRSSLAEDNESS 259
>gi|31657138 follicle stimulating hormone receptor isoform 1
precursor [Homo sapiens]
Length = 695
Score = 124 bits (311), Expect = 9e-29
Identities = 83/227 (36%), Positives = 120/227 (52%), Gaps = 9/227 (3%)
Query: 6 LLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPS-LPPSTQTLKLIETHL 64
L+ L+ L L G GC C C F + IPS LP + L+ + T L
Sbjct: 5 LVSLLAFLSL-----GSGCHHRICHCSNRV-FLCQESKVTEIPSDLPRNAIELRFVLTKL 58
Query: 65 RTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKE 124
R I AFS ++ +I +S + L+ +E+ F NL K+ I I NL YI+P+A +
Sbjct: 59 RVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQN 118
Query: 125 LPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKL 184
LP L++L I NTG+K PD+ K++S +L+I DN + +I N+F GL E++ L L
Sbjct: 119 LPNLQYLLISNTGIKHLPDVHKIHSLQ-KVLLDIQDNINIHTIERNSFVGLSFESVILWL 177
Query: 185 YNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL 231
NG + AFNGT+LD + L+ N L + D F G SGP +L
Sbjct: 178 NKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGA-SGPVIL 223
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 57.0 bits (136), Expect = 2e-08
Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 6/117 (5%)
Query: 29 CECHQEEDFRVTCKDIQRI---PSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSI 85
C+C V C + P +P +T+TL L+ L +PS AF+NL ++ R+ +S
Sbjct: 43 CKC-DSRSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSN 101
Query: 86 DVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFP 142
+ L +L F +L+ +T +++RN ++ +D D L+ PLL+ L + GL P
Sbjct: 102 NF-LDRLPRSIFGDLTNLTELQLRN-NSIRTLDRDLLRHSPLLRHLDLSINGLAQLP 156
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 52.0 bits (123), Expect = 6e-07
Identities = 41/165 (24%), Positives = 83/165 (50%), Gaps = 7/165 (4%)
Query: 52 PSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNT 111
PS TL+L + L T+P+ AF L + +++ + ++ + S++F + + +++
Sbjct: 134 PSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNN-PIESIPSYAFNRVPSLRRLDLGEL 192
Query: 112 RNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNA 171
+ L YI A + L L++L + LK P+LT + + LE++ N + I +
Sbjct: 193 KRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLE---ELELSGN-RLDLIRPGS 248
Query: 172 FQGLCNETLTLKLYNNGFTSVQGYAFNGTK-LDAVYLNKNKYLTV 215
FQGL L L + +++ AF+ K L+ + L+ N +++
Sbjct: 249 FQGL-TSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSL 292
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 51.2 bits (121), Expect = 1e-06
Identities = 31/120 (25%), Positives = 66/120 (55%), Gaps = 5/120 (4%)
Query: 56 TLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLT 115
TL+L + L TIP+ AF L + +++ + ++ + S++F + + +++ + L+
Sbjct: 128 TLELFDNRLTTIPNGAFVYLSKLKELWLRNN-PIESIPSYAFNRIPSLRRLDLGELKRLS 186
Query: 116 YIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGL 175
YI A + L L++L + L+ P+LT + D L+++ N ++++I +FQGL
Sbjct: 187 YISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLD---ELDLSGN-HLSAIRPGSFQGL 242
>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
Length = 473
Score = 50.1 bits (118), Expect = 2e-06
Identities = 46/188 (24%), Positives = 95/188 (50%), Gaps = 10/188 (5%)
Query: 29 CECHQEEDFRVTC--KDIQRIP-SLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSI 85
C C+ E +C + +Q +P +P ++Q + L + +P+ +F N++ +++
Sbjct: 31 CVCYNEPKVTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHS 90
Query: 86 DVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGL-KMFPDL 144
+V L ++++ +F L+ + +++ + L +DP L L L + GL ++ P L
Sbjct: 91 NV-LARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGL 149
Query: 145 TKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGT-KLD 203
+ + + L+ DN + ++P + F+ L N T L L+ N +SV AF G LD
Sbjct: 150 FRGLAALQYLYLQ--DNA-LQALPDDTFRDLGNLT-HLFLHGNRISSVPERAFRGLHSLD 205
Query: 204 AVYLNKNK 211
+ L++N+
Sbjct: 206 RLLLHQNR 213
>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
Length = 653
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/147 (25%), Positives = 73/147 (49%), Gaps = 6/147 (4%)
Query: 53 STQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTR 112
S TL+L + L IPS AF L + +++ + ++ + S++F + + +++ +
Sbjct: 124 SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN-PIESIPSYAFNRVPSLMRLDLGELK 182
Query: 113 NLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAF 172
L YI A + L LK+L + +K P+LT + + LE++ N + I +F
Sbjct: 183 KLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLE---ELEMSGN-HFPEIRPGSF 238
Query: 173 QGLCNETLTLKLYNNGFTSVQGYAFNG 199
GL + L + N+ + ++ AF+G
Sbjct: 239 HGL-SSLKKLWVMNSQVSLIERNAFDG 264
>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
Length = 420
Score = 45.8 bits (107), Expect = 4e-05
Identities = 57/228 (25%), Positives = 103/228 (45%), Gaps = 19/228 (8%)
Query: 3 PADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCK--DIQRIP-SLPPSTQTLKL 59
PA L++LL LP L C C C+ V+C+ + +P SLPPSTQ L L
Sbjct: 12 PASACLLLMLLALP--LAAPSCPML-CTCYSSPP-TVSCQANNFSSVPLSLPPSTQRLFL 67
Query: 60 IETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDP 119
+RT+ F + N+ +++ L + +F +L + +++ + R+L ++P
Sbjct: 68 QNNLIRTLRPGTFGS--NLLTLWL-FSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEP 124
Query: 120 DALKELPLLKFLGIFNTGLKMFPD--LTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCN 177
D + L L+ L ++ L P + S ++ E + + + + F L N
Sbjct: 125 DTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENS----LLHLQDDLFADLAN 180
Query: 178 ETLTLKLYNNGFTSVQGYAFNGT-KLDAVYLNKNKYLTVIDKDAFGGV 224
+ L L+ N + + F G LD + L+ N+ L + + AF G+
Sbjct: 181 LS-HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNR-LQGVHRAAFRGL 226
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 45.1 bits (105), Expect = 7e-05
Identities = 43/178 (24%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 52 PSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNT 111
P+ Q L L + +IP AF+NL ++ +++ + ++ L H F L + +++ N
Sbjct: 177 PTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNN-KIRSLSQHCFDGLDNLETLDL-NY 234
Query: 112 RNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNA 171
NL P A+K LP LK LG + + + PD + + + DNP ++ + +A
Sbjct: 235 NNLGEF-PQAIKALPSLKELGFHSNSISVIPD-GAFDGNPLLRTIHLYDNP-LSFVGNSA 291
Query: 172 FQGLCN-ETLTLKLYN--------NGFTSVQGYAFNGTKLDAVYLN---KNKYLTVID 217
F L + +L ++ + G ++ GTK+ ++ N + K L +D
Sbjct: 292 FHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLD 349
Score = 29.6 bits (65), Expect = 3.0
Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 12/121 (9%)
Query: 100 LSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEI- 158
LS T + N+T + DA K P L+ L + DL+ ++ + + E+
Sbjct: 55 LSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGN------DLSFIHPKALSGLKELK 108
Query: 159 ---TDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNG-TKLDAVYLNKNKYLT 214
N + ++P A +GL + +L+L N TSV +F G +L ++L+ N
Sbjct: 109 VLTLQNNQLKTVPSEAIRGL-SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTE 167
Query: 215 V 215
V
Sbjct: 168 V 168
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 44.7 bits (104), Expect = 9e-05
Identities = 57/204 (27%), Positives = 89/204 (43%), Gaps = 15/204 (7%)
Query: 12 LLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHA 71
L LP+ L G H R+ D + SL T+ L+ H+R+I A
Sbjct: 182 LTHLPKGLLGAQAKLERLLLHSN---RLVSLDSGLLNSLGALTE-LQFHRNHIRSIAPGA 237
Query: 72 FSNLPNISRIYVS---IDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLL 128
F LPN+S + +S + L HS +NL+ +T E L + E+ L
Sbjct: 238 FDRLPNLSSLTLSRNHLAFLPSALFLHS-HNLTLLTLFE----NPLAELPGVLFGEMGGL 292
Query: 129 KFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNG 188
+ L + T L+ P + L +T +P ++++P AFQGL E L L++NG
Sbjct: 293 QELWLNRTQLRTLP-AAAFRNLSRLRYLGVTLSPRLSALPQGAFQGL-GELQVLALHSNG 350
Query: 189 FTSVQGYAFNGT-KLDAVYLNKNK 211
T++ G KL V L +N+
Sbjct: 351 LTALPDGLLRGLGKLRQVSLRRNR 374
Score = 35.8 bits (81), Expect = 0.041
Identities = 33/138 (23%), Positives = 64/138 (46%), Gaps = 13/138 (9%)
Query: 55 QTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNL 114
Q L L T LRT+P+ AF NL + + V++ L L +F L ++ + + ++ L
Sbjct: 293 QELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL-HSNGL 351
Query: 115 TYIDPDALKELPLLKFLGIFNTGLK-----MFPDLTKVYSTDIFFILEITDNPYMTSIPV 169
T + L+ L L+ + + L+ +F +L+ + S + D+ + ++P
Sbjct: 352 TALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQL-------DHNQLETLPG 404
Query: 170 NAFQGLCNETLTLKLYNN 187
+ F L T L +N+
Sbjct: 405 DVFGALPRLTEVLLGHNS 422
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 11/125 (8%)
Query: 24 CSSPP-CECHQEEDFRVTCKD--IQRIPS-LPPSTQTLKLIETHLRTIPSHAFSNLPNIS 79
CS P C C +F V C + IPS LPP T+TL L + + +P+ AF ++P +
Sbjct: 19 CSCPDKCYCQSSTNF-VDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLM 77
Query: 80 RIYVSIDVTLQQLESHSFYNLSKVTHIEIRN-TRN-LTYIDPDALKELPLLKFLGIFNTG 137
+ +S + +L L +F+ L H+++ N T+N L ++ LP L+ L + +
Sbjct: 78 TLNLS-NNSLSNLAPGAFHGLQ---HLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNN 133
Query: 138 LKMFP 142
+ P
Sbjct: 134 ISHLP 138
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 43.5 bits (101), Expect = 2e-04
Identities = 61/238 (25%), Positives = 101/238 (42%), Gaps = 31/238 (13%)
Query: 3 PADLLQLVLLLDLPRDLGGMGCSSP---PCECHQEEDFRVTC--KDIQRIPS-LPPSTQT 56
P LL +LLL L G +P C C + + C + + +P LP T++
Sbjct: 16 PCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDS---LDCGGRGLAALPGDLPSWTRS 72
Query: 57 LKLIETHLRTIPSHAFSNLPNISRIYVSIDV-----TLQQLESHS---FYNLSKVTHIEI 108
L L L I F +LPN+ +Y++ + +L SH F +K+ +E
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVE- 131
Query: 109 RNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIP 168
++ Y+ + L +L L + NT P + + L + N T +
Sbjct: 132 -GSQLKAYLSLEVL-DLSLNNITEVRNTCFPHGPPIKE---------LNLAGNRIGT-LE 179
Query: 169 VNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYS 226
+ AF GL LTL+L N T + AF +L + LN+N+ + +I+ F G+ S
Sbjct: 180 LGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNR-IRLIEGLTFQGLNS 236
>gi|153251229 chondroadherin precursor [Homo sapiens]
Length = 359
Score = 42.7 bits (99), Expect = 3e-04
Identities = 46/215 (21%), Positives = 102/215 (47%), Gaps = 14/215 (6%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCK-DIQRIPSLPPSTQTLKL 59
+RP LL L LL L L + C CH + + K +Q+IP + T+ L L
Sbjct: 2 VRPMLLLSLGLLAGL---LPALAACPQNCHCHSDLQHVICDKVGLQKIPKVSEKTKLLNL 58
Query: 60 IETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDP 119
+ + +++F +PN+ +++ ++++ + +F L ++ ++ + + ++ +
Sbjct: 59 QRNNFPVLAANSFRAMPNLVSLHLQ-HCQIREVAAGAFRGLKQLIYLYLSH-NDIRVLRA 116
Query: 120 DALKELPLLKFLGIFNTGLKMFPD--LTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCN 177
A +L L +L + + + P L+ + + FIL++ +N + + AFQG
Sbjct: 117 GAFDDLTELTYLYLDHNKVTELPRGLLSPLVN---LFILQLNNNK-IRELRAGAFQG-AK 171
Query: 178 ETLTLKLYNNGFTSVQGYAFNGTK-LDAVYLNKNK 211
+ L L N +S+Q A + + L ++++N+
Sbjct: 172 DLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQ 206
Score = 28.9 bits (63), Expect = 5.1
Identities = 18/80 (22%), Positives = 33/80 (41%), Gaps = 4/80 (5%)
Query: 37 FRVTCKDIQRIPSLPPS----TQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQL 92
F V + PS S + LKL L++IP +AF + + L++
Sbjct: 200 FHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKF 259
Query: 93 ESHSFYNLSKVTHIEIRNTR 112
+F ++ + H+ + N R
Sbjct: 260 SDGAFLGVTTLKHVHLENNR 279
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 42.4 bits (98), Expect = 4e-04
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 36/241 (14%)
Query: 18 DLGGMGCSSPPCECHQEEDFRVTC-----------KDIQRIPS-LPPSTQTLKLIETHLR 65
D GG G P E TC K + R+P LP L L L
Sbjct: 28 DSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARLPEPLPSWVARLDLSHNRLS 87
Query: 66 TIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNL----SKVTHIEIRNTRNLTYIDPDA 121
I + + S+L ++ +V L E + NL + +T + + R + I P+
Sbjct: 88 FIKASSMSHLQSLR------EVKLNNNELETIPNLGPVSANITLLSLAGNR-IVEILPEH 140
Query: 122 LKELPLLKFLGIFNTGLK----MFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCN 177
LKE L+ L + + + FP L Y L + N +TS+ F L N
Sbjct: 141 LKEFQSLETLDLSSNNISELQTAFPALQLKY-------LYLNSNR-VTSMEPGYFDNLAN 192
Query: 178 ETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAV 237
L LKL N +++ F +L + LN+NK + +D F G+ + SL ++ V
Sbjct: 193 TLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNK-IKNVDGLTFQGLGALKSLKMQRNGV 251
Query: 238 S 238
+
Sbjct: 252 T 252
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 42.0 bits (97), Expect = 6e-04
Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 42/234 (17%)
Query: 10 VLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKD--IQRIP-SLPPSTQTLKLIETHLRT 66
+LLL P MGC +C +E F C D + +P +PP T+ + +ET T
Sbjct: 12 LLLLARPAQPCPMGC-----DCFVQEVF---CSDEELATVPLDIPPYTKNIIFVETSFTT 63
Query: 67 IPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELP 126
+ + AF + PN++++ V ++ L Q +F L ++ +E+ +
Sbjct: 64 LETRAFGSNPNLTKV-VFLNTQLCQFRPDAFGGLPRLEDLEVTGS--------------- 107
Query: 127 LLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYN 186
N +F +LT + + F + + ++P FQ L +L L
Sbjct: 108 -----SFLNLSTNIFSNLTSLGKLTLNFNM-------LEALPEGLFQHLA-ALESLHLQG 154
Query: 187 NGFTSVQGYAFNG-TKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLVENVAVSG 239
N ++ F T L + L +N L + ++ F + S +L + N A+SG
Sbjct: 155 NQLQALPRRLFQPLTHLKTLNLAQN-LLAQLPEELFHPLTSLQTLKLSNNALSG 207
>gi|62912472 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 2 [Homo sapiens]
Length = 915
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/145 (25%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Query: 52 PSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNT 111
P+ Q + L + IP +AF NL ++ +++ + +Q L +HSF L + +++
Sbjct: 134 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLH-NNRIQHLGTHSFEGLHNLETLDLNYN 192
Query: 112 RNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNA 171
+ + P A++ L L+ LG N +K P+ + + DNP + + +A
Sbjct: 193 KLQEF--PVAIRTLGRLQELGFHNNNIKAIPE-KAFMGNPLLQTIHFYDNP-IQFVGRSA 248
Query: 172 FQGLCN-ETLTLKLYNNGFTSVQGY 195
FQ L TL+L NG +Q +
Sbjct: 249 FQYLPKLHTLSL----NGAMDIQEF 269
Score = 32.0 bits (71), Expect = 0.60
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 8/159 (5%)
Query: 55 QTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNL 114
+ L+L HL IP AFS L ++ +I + + L + + + + L + +R NL
Sbjct: 41 EELRLSGNHLSHIPGQAFSGLYSL-KILMLQNNQLGGIPAEALWELPSLQ--SLRLDANL 97
Query: 115 TYIDPD-ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQ 173
+ P+ + + L L+ L + + L P + + + + + N ++ IP AFQ
Sbjct: 98 ISLVPERSFEGLSSLRHLWLDDNALTEIP-VRALNNLPALQAMTLALN-RISHIPDYAFQ 155
Query: 174 GLCNETLTLKLYNNGFTSVQGYAFNGT-KLDAVYLNKNK 211
L + L L+NN + ++F G L+ + LN NK
Sbjct: 156 NL-TSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 193
Score = 30.4 bits (67), Expect = 1.7
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
Query: 27 PPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLR-----TIPSHAFSNLPNISRI 81
P C Q RV +I LP + KL E L+ I + FS L ++ +
Sbjct: 292 PSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQAL 351
Query: 82 YVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMF 141
+S + ++ + +F L + +++ + + L LPL G+ + LK
Sbjct: 352 DLSWNA-IRSIHPEAFSTLHSLVKLDLTDNQ---------LTTLPLAGLGGLMHLKLKGN 401
Query: 142 PDLTKVYSTDIFFILEITDNPY 163
L++ +S D F L I + PY
Sbjct: 402 LALSQAFSKDSFPKLRILEVPY 423
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/189 (21%), Positives = 82/189 (43%), Gaps = 33/189 (17%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRV---TCKDIQRI-PSLPPSTQT 56
M+ LL LLL L + PC+C ++ F++ +D++ + P P + T
Sbjct: 1 MQELHLLWWALLLGLAQ------ACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTT 54
Query: 57 LKLIETHLRTIPSHAFSNLPNISRIYV--------------------SIDVTLQQLESHS 96
L L L +P AF +P + +++ S+D++ + +
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 97 FYNLSKVTHIEI--RNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFF 154
+ +L ++ +++ ++ LT+I DA + L L+ L + + L + T T +
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 155 ILEITDNPY 163
L+I +NP+
Sbjct: 175 -LQINENPF 182
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/145 (25%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Query: 52 PSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNT 111
P+ Q + L + IP +AF NL ++ +++ + +Q L +HSF L + +++
Sbjct: 186 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLH-NNRIQHLGTHSFEGLHNLETLDLNYN 244
Query: 112 RNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNA 171
+ + P A++ L L+ LG N +K P+ + + DNP + + +A
Sbjct: 245 KLQEF--PVAIRTLGRLQELGFHNNNIKAIPE-KAFMGNPLLQTIHFYDNP-IQFVGRSA 300
Query: 172 FQGLCN-ETLTLKLYNNGFTSVQGY 195
FQ L TL+L NG +Q +
Sbjct: 301 FQYLPKLHTLSL----NGAMDIQEF 321
Score = 32.0 bits (71), Expect = 0.60
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 8/159 (5%)
Query: 55 QTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNL 114
+ L+L HL IP AFS L ++ +I + + L + + + + L + +R NL
Sbjct: 93 EELRLSGNHLSHIPGQAFSGLYSL-KILMLQNNQLGGIPAEALWELPSLQ--SLRLDANL 149
Query: 115 TYIDPD-ALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQ 173
+ P+ + + L L+ L + + L P + + + + + N ++ IP AFQ
Sbjct: 150 ISLVPERSFEGLSSLRHLWLDDNALTEIP-VRALNNLPALQAMTLALN-RISHIPDYAFQ 207
Query: 174 GLCNETLTLKLYNNGFTSVQGYAFNGT-KLDAVYLNKNK 211
L + L L+NN + ++F G L+ + LN NK
Sbjct: 208 NL-TSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 245
Score = 30.4 bits (67), Expect = 1.7
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 15/142 (10%)
Query: 27 PPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLR-----TIPSHAFSNLPNISRI 81
P C Q RV +I LP + KL E L+ I + FS L ++ +
Sbjct: 344 PSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQAL 403
Query: 82 YVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMF 141
+S + ++ + +F L + +++ + + L LPL G+ + LK
Sbjct: 404 DLSWNA-IRSIHPEAFSTLHSLVKLDLTDNQ---------LTTLPLAGLGGLMHLKLKGN 453
Query: 142 PDLTKVYSTDIFFILEITDNPY 163
L++ +S D F L I + PY
Sbjct: 454 LALSQAFSKDSFPKLRILEVPY 475
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/189 (21%), Positives = 82/189 (43%), Gaps = 33/189 (17%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRV---TCKDIQRI-PSLPPSTQT 56
M+ LL LLL L + PC+C ++ F++ +D++ + P P + T
Sbjct: 1 MQELHLLWWALLLGLAQ------ACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTT 54
Query: 57 LKLIETHLRTIPSHAFSNLPNISRIYV--------------------SIDVTLQQLESHS 96
L L L +P AF +P + +++ S+D++ + +
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 97 FYNLSKVTHIEI--RNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFF 154
+ +L ++ +++ ++ LT+I DA + L L+ L + + L + T T +
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 155 ILEITDNPY 163
L+I +NP+
Sbjct: 175 -LQINENPF 182
>gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens]
Length = 620
Score = 39.7 bits (91), Expect = 0.003
Identities = 60/231 (25%), Positives = 99/231 (42%), Gaps = 39/231 (16%)
Query: 3 PADLL---QLVLLLDLPRDLGGMGCSSPP-CECHQEEDFRVTC--KDIQRIPS-LPPSTQ 55
P+ LL Q +LLL L L G PP CEC +D V C K +P +P T+
Sbjct: 16 PSPLLACWQPILLLVLGSVLSGSATGCPPRCEC-SAQDRAVLCHRKRFVAVPEGIPTETR 74
Query: 56 TLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLT 115
L L + ++T+ F++ P+ L++LE N ++
Sbjct: 75 LLDLGKNRIKTLNQDEFASFPH-----------LEELEL---------------NENIVS 108
Query: 116 YIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGL 175
++P A L L+ LG+ + LK+ P L L+I++N + + FQ L
Sbjct: 109 AVEPGAFNNLFNLRTLGLRSNRLKLIP-LGVFTGLSNLTKLDISENKIVILLDY-MFQDL 166
Query: 176 CNETLTLKLYNNGFTSVQGYAFNG-TKLDAVYLNKNKYLTVIDKDAFGGVY 225
N +L++ +N + AF+G L+ + L K LT I +A ++
Sbjct: 167 YN-LKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCN-LTSIPTEALSHLH 215
Score = 31.6 bits (70), Expect = 0.78
Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 82/283 (28%)
Query: 55 QTLKLIETHLRTIPSHAFSNLPNISRIYVS-------IDVTLQQLES------------- 94
+TL L L+ IP F+ L N++++ +S +D Q L +
Sbjct: 122 RTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVY 181
Query: 95 ---HSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLT--KVYS 149
+F L+ + + + NLT I +AL L L L + + + D + ++Y
Sbjct: 182 ISHRAFSGLNSLEQLTLEKC-NLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR 240
Query: 150 TDIFFILEITDNPYMTSIPVNAFQGL---------CNETLT-------------LKLYNN 187
+ LEI+ PY+ ++ N GL CN T L L N
Sbjct: 241 LKV---LEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYN 297
Query: 188 GFTSVQG------------------------YAFNGTKLDAVYLNKNKYLTVIDKDAFGG 223
++++G YAF G V LT +++ F
Sbjct: 298 PISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHS 357
Query: 224 VYSGPSLLVENVAVSGKGFCKSLFSWLYRLPLGRKSLSFETQK 266
V + +L++++ ++ C W++R R L+F Q+
Sbjct: 358 VGNLETLILDSNPLA----CDCRLLWVFR---RRWRLNFNRQQ 393
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 39.7 bits (91), Expect = 0.003
Identities = 37/151 (24%), Positives = 71/151 (47%), Gaps = 7/151 (4%)
Query: 44 IQRIPS-LPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSID-VTLQQLESHSFYNLS 101
++ +P LPP+ L L L IP AFS L ++ +Y+ + +T + L++ +F+ LS
Sbjct: 277 LRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLS 336
Query: 102 KVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDN 161
+ ++++ ++ NL+ + + L LL + ++ + ++L ++
Sbjct: 337 SLEYLDL-SSNNLSRVPAGLPRSLVLLH---LEKNAIRSVDANVLTPIRSLEYLLLHSNQ 392
Query: 162 PYMTSIPVNAFQGLCNETLTLKLYNNGFTSV 192
I AFQGL T+ LYNN V
Sbjct: 393 LREQGIHPLAFQGL-KRLHTVHLYNNALERV 422
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 39.7 bits (91), Expect = 0.003
Identities = 40/163 (24%), Positives = 67/163 (41%), Gaps = 28/163 (17%)
Query: 7 LQLVLLLDLPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIP-SLPPST----------- 54
L L LLL L G GC S C+C Q + T + +P +PP T
Sbjct: 7 LLLPLLLLLALGPGVQGCPSG-CQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGIT 65
Query: 55 -------------QTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLS 101
Q L L + + ++PS F L N+S + ++ + L ++ + +F L
Sbjct: 66 MLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTAN-RLHEITNETFRGLR 124
Query: 102 KVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDL 144
++ + + R + +I P A L L L + + L+ P L
Sbjct: 125 RLERLYLGKNR-IRHIQPGAFDTLDRLLELKLQDNELRALPPL 166
>gi|14149694 retina specific protein PAL [Homo sapiens]
Length = 623
Score = 39.3 bits (90), Expect = 0.004
Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 10/171 (5%)
Query: 1 MRPADLLQLVLLLDLPRDLGGMGCSSPPCECHQEEDFR----VTCKDIQRI---PSLPPS 53
MR A + +L L P G S C H D V C D S+PP
Sbjct: 1 MRVALGMLWLLALAWPPQARGFCPSQCSCSLHIMGDGSKARTVVCNDPDMTLPPASIPPD 60
Query: 54 TQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRN 113
T L+L T +R +P AF L + ++++ + L +L + L ++ + + R
Sbjct: 61 TSRLRLERTAIRRVPGEAFRPLGRLEQLWLPYN-ALSELNALMLRGLRRLRELRLPGNR- 118
Query: 114 LTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYM 164
L AL++ P L+ L + L P + ++ F L+++ N M
Sbjct: 119 LAAFPWAALRDAPKLRLLDLQANRLSAVPAEAARFLENLTF-LDLSSNQLM 168
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 38.9 bits (89), Expect = 0.005
Identities = 49/192 (25%), Positives = 85/192 (44%), Gaps = 26/192 (13%)
Query: 29 CECHQEEDFRVTCKDI--QRIPS-LPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSI 85
C+CH V C D+ ++P LPP T L L + I F NL N+ + + +
Sbjct: 58 CQCHLRV---VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL-ILV 113
Query: 86 DVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELP--LLKFLGIFNTGLKMFPD 143
+ + ++ +F L K+ + Y+ + LKELP + K L
Sbjct: 114 NNKISKVSPGAFTPLVKLERL---------YLSKNQLKELPEKMPKTLQELRAHENEITK 164
Query: 144 LTKVYSTDI--FFILEITDNPYMTS-IPVNAFQGLCNETLTLKLYNNGFTSV-QGYAFNG 199
+ KV + ++E+ NP +S I AFQG+ + +++ + TS+ QG +
Sbjct: 165 VRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGM-KKLSYIRIADTNITSIPQGLPPSL 223
Query: 200 TKLDAVYLNKNK 211
T+L +L+ NK
Sbjct: 224 TEL---HLDGNK 232
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 38.9 bits (89), Expect = 0.005
Identities = 49/192 (25%), Positives = 85/192 (44%), Gaps = 26/192 (13%)
Query: 29 CECHQEEDFRVTCKDI--QRIPS-LPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSI 85
C+CH V C D+ ++P LPP T L L + I F NL N+ + + +
Sbjct: 58 CQCHLRV---VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL-ILV 113
Query: 86 DVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELP--LLKFLGIFNTGLKMFPD 143
+ + ++ +F L K+ + Y+ + LKELP + K L
Sbjct: 114 NNKISKVSPGAFTPLVKLERL---------YLSKNQLKELPEKMPKTLQELRAHENEITK 164
Query: 144 LTKVYSTDI--FFILEITDNPYMTS-IPVNAFQGLCNETLTLKLYNNGFTSV-QGYAFNG 199
+ KV + ++E+ NP +S I AFQG+ + +++ + TS+ QG +
Sbjct: 165 VRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGM-KKLSYIRIADTNITSIPQGLPPSL 223
Query: 200 TKLDAVYLNKNK 211
T+L +L+ NK
Sbjct: 224 TEL---HLDGNK 232
>gi|4507531 toll-like receptor 3 [Homo sapiens]
Length = 904
Score = 38.5 bits (88), Expect = 0.006
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 48/202 (23%)
Query: 21 GMGCSSPPCECHQEEDFRVTCKDIQ--RIPS-LPPSTQTLKLIETHLRTIPSHAFSNLPN 77
GM C+S +C + C ++ ++P LP + L L LR +P+ F+
Sbjct: 18 GMLCASSTTKCTVSHEV-ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQ 76
Query: 78 ISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTG 137
++ S+DV F +SK ++P+ ++LP+LK L + +
Sbjct: 77 LT----SLDV--------GFNTISK--------------LEPELCQKLPMLKVLNLQHNE 110
Query: 138 LKMFPDLTKVYSTDIF-------FILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFT 190
L D T + T++ I +I +NP++ +TL L +NG +
Sbjct: 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ----------KNLITLDLSHNGLS 160
Query: 191 SVQ-GYAFNGTKLDAVYLNKNK 211
S + G L + L+ NK
Sbjct: 161 STKLGTQVQLENLQELLLSNNK 182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,615,035
Number of Sequences: 37866
Number of extensions: 467116
Number of successful extensions: 1242
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 1127
Number of HSP's gapped (non-prelim): 176
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.