BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|217035118 TBC1 domain family, member 23 [Homo sapiens] (684 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|217035118 TBC1 domain family, member 23 [Homo sapiens] 1373 0.0 gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 54 6e-07 gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 49 1e-05 gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 49 1e-05 gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 47 8e-05 gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 44 6e-04 gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 44 6e-04 gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 44 6e-04 gi|34147456 TBC domain-containing protein kinase-like [Homo sapi... 43 8e-04 gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 39 0.021 gi|22507409 TBC1 domain family, member 22A [Homo sapiens] 37 0.061 gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 35 0.23 gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 35 0.23 gi|13375952 TBC1 domain family, member 17 [Homo sapiens] 35 0.23 gi|221139907 TBC1 domain family, member 7 isoform a [Homo sapiens] 35 0.30 gi|221139904 TBC1 domain family, member 7 isoform a [Homo sapiens] 35 0.30 gi|7706041 TBC1 domain family, member 7 isoform a [Homo sapiens] 35 0.30 gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 34 0.39 gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 34 0.39 gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 34 0.39 gi|157388983 TBC1 domain family, member 19 [Homo sapiens] 33 0.67 gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 33 0.67 gi|119220552 sidekick 1 [Homo sapiens] 33 0.87 gi|23397642 GREB1 protein isoform a [Homo sapiens] 33 0.87 gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 33 0.87 gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 33 1.1 gi|125625350 cell division cycle 25C isoform a [Homo sapiens] 32 2.5 gi|12408658 cell division cycle 25C isoform b [Homo sapiens] 32 2.5 gi|16975496 cortactin binding protein 2 [Homo sapiens] 32 2.5 gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens] 31 3.3 >gi|217035118 TBC1 domain family, member 23 [Homo sapiens] Length = 684 Score = 1373 bits (3555), Expect = 0.0 Identities = 684/684 (100%), Positives = 684/684 (100%) Query: 1 MAEGEDVPPLPTSSGDGWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNV 60 MAEGEDVPPLPTSSGDGWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNV Sbjct: 1 MAEGEDVPPLPTSSGDGWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNV 60 Query: 61 AGKGDSLASWDGILDLPEQNTIHKDCLQFIDQLSVPEEKAAELLLDIESVITFYCKSRNI 120 AGKGDSLASWDGILDLPEQNTIHKDCLQFIDQLSVPEEKAAELLLDIESVITFYCKSRNI Sbjct: 61 AGKGDSLASWDGILDLPEQNTIHKDCLQFIDQLSVPEEKAAELLLDIESVITFYCKSRNI 120 Query: 121 KYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEP 180 KYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEP Sbjct: 121 KYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEP 180 Query: 181 ELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVN 240 ELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVN Sbjct: 181 ELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVN 240 Query: 241 AKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYCSKTPASFRKDNHHLFGS 300 AKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYCSKTPASFRKDNHHLFGS Sbjct: 241 AKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYCSKTPASFRKDNHHLFGS 300 Query: 301 TLLGIKDDDADLSQALCLAISVSEILQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHL 360 TLLGIKDDDADLSQALCLAISVSEILQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHL Sbjct: 301 TLLGIKDDDADLSQALCLAISVSEILQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHL 360 Query: 361 DSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFL 420 DSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFL Sbjct: 361 DSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFL 420 Query: 421 QKNKEYVSIASGGFMALQQHLADINVDGPENGYGHWIASTSGSRSSINSVDGESPNGSSD 480 QKNKEYVSIASGGFMALQQHLADINVDGPENGYGHWIASTSGSRSSINSVDGESPNGSSD Sbjct: 421 QKNKEYVSIASGGFMALQQHLADINVDGPENGYGHWIASTSGSRSSINSVDGESPNGSSD 480 Query: 481 RGMKSLVNKMTVALKTKSVNVREKVISFIENTSTPVDRHVSSSDRVGKPYRGVKPVFSIG 540 RGMKSLVNKMTVALKTKSVNVREKVISFIENTSTPVDRHVSSSDRVGKPYRGVKPVFSIG Sbjct: 481 RGMKSLVNKMTVALKTKSVNVREKVISFIENTSTPVDRHVSSSDRVGKPYRGVKPVFSIG 540 Query: 541 DEEEYDTDEIDSSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTAT 600 DEEEYDTDEIDSSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTAT Sbjct: 541 DEEEYDTDEIDSSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTAT 600 Query: 601 HMYCLREIVSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSSASGIEILAIERYL 660 HMYCLREIVSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSSASGIEILAIERYL Sbjct: 601 HMYCLREIVSRKGLAYIQSRQALNSVVKITSKKKHPELITFKYGNSSASGIEILAIERYL 660 Query: 661 IPNAGDATKAIKQQIMKVLDALES 684 IPNAGDATKAIKQQIMKVLDALES Sbjct: 661 IPNAGDATKAIKQQIMKVLDALES 684 >gi|114688046 TBC1 domain family, member 4 [Homo sapiens] Length = 1298 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/123 (27%), Positives = 66/123 (53%), Gaps = 4/123 (3%) Query: 155 KYIPRDCSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVT 214 +Y P S + + + L RLL YH +L ++L+ +I+P YA W +LFA S Sbjct: 1043 QYRPDMMSLQIQMYQLSRLLHDYHR-DLYNHLEENEISPSLYAAPWFLTLFASQFSLGFV 1101 Query: 215 QAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDIED 274 ++D Q + F + + L++++E ++ E +S E +++FL+NT +N ++E Sbjct: 1102 ARVFDIIFLQGTE--VIFKVALSLLSSQETLI-MECESFENIVEFLKNTLPDMNTSEMEK 1158 Query: 275 LFS 277 + + Sbjct: 1159 IIT 1161 >gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] Length = 963 Score = 49.3 bits (116), Expect = 1e-05 Identities = 55/269 (20%), Positives = 105/269 (39%), Gaps = 24/269 (8%) Query: 13 SSGDGWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALN----------VAG 62 S+G WE + L+N+I+ +P + R+KVWK ++ G Sbjct: 632 STGVKWENYFASTVNREMMCSPELKNLIRAG-IPHEHRSKVWKWCVDRHTRKFKDNTEPG 690 Query: 63 KGDSLASWDGILDLPEQNTIHKDCLQFIDQ---LSVPEEKAAELLLDIESVITFYCKSRN 119 +L P I D L+ + S P + + L ++ ++ F ++ + Sbjct: 691 HFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNV--LLAFSWRNPD 748 Query: 120 IKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGR-----PFHLFRLL 174 I Y L+ L + L L + D + C I+ ++PRD K +FR L Sbjct: 749 IGYCQGLN---RLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDL 805 Query: 175 IQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLM 234 + P L + + K+ NW +F +++ IWD +L + F + Sbjct: 806 MSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFAL 865 Query: 235 LIILVNAKEVILTQESDSKEEVIKFLENT 263 + +E++ Q+S S + +++ T Sbjct: 866 ALFKYKEEEILKLQDSMSIFKYLRYFTRT 894 >gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] Length = 914 Score = 49.3 bits (116), Expect = 1e-05 Identities = 55/269 (20%), Positives = 105/269 (39%), Gaps = 24/269 (8%) Query: 13 SSGDGWEKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALN----------VAG 62 S+G WE + L+N+I+ +P + R+KVWK ++ G Sbjct: 632 STGVKWENYFASTVNREMMCSPELKNLIRAG-IPHEHRSKVWKWCVDRHTRKFKDNTEPG 690 Query: 63 KGDSLASWDGILDLPEQNTIHKDCLQFIDQ---LSVPEEKAAELLLDIESVITFYCKSRN 119 +L P I D L+ + S P + + L ++ ++ F ++ + Sbjct: 691 HFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNV--LLAFSWRNPD 748 Query: 120 IKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGR-----PFHLFRLL 174 I Y L+ L + L L + D + C I+ ++PRD K +FR L Sbjct: 749 IGYCQGLN---RLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDL 805 Query: 175 IQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLM 234 + P L + + K+ NW +F +++ IWD +L + F + Sbjct: 806 MSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFAL 865 Query: 235 LIILVNAKEVILTQESDSKEEVIKFLENT 263 + +E++ Q+S S + +++ T Sbjct: 866 ALFKYKEEEILKLQDSMSIFKYLRYFTRT 894 >gi|148806902 TBC1 domain family, member 12 [Homo sapiens] Length = 775 Score = 46.6 bits (109), Expect = 8e-05 Identities = 45/216 (20%), Positives = 95/216 (43%), Gaps = 19/216 (8%) Query: 107 IESVITFY-CKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNK-----YIPRD 160 + S++ Y C ++ Y +S+I ++ L L +D + F ++NK + D Sbjct: 571 LHSILGAYTCYRPDVGYVQGMSFI---AAVLILNLEEADAFIAFANLLNKPCQLAFFRVD 627 Query: 161 CSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDG 220 S + F F + + + +L + + +TPD Y ++W+ +L++ ++ +WD Sbjct: 628 HSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDV 687 Query: 221 YLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQ 280 + + + F++ L IL ++++L + + +FL P + E + + Q Sbjct: 688 FCRDGEE-FLFRTGLGILRLYEDILLQMDF---IHIAQFLTKLPEDITSEKLFSCIAAIQ 743 Query: 281 YYCSKTPASFRKDNHHLFGSTLLGIKDDDADLSQAL 316 S K +F S + IK+ D + S AL Sbjct: 744 MQNS------TKKWTQVFASVMKDIKEGDKNSSPAL 773 >gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] Length = 413 Score = 43.5 bits (101), Expect = 6e-04 Identities = 37/172 (21%), Positives = 77/172 (44%), Gaps = 13/172 (7%) Query: 107 IESVITFY-CKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNK-----YIPRD 160 + S++ Y C ++ Y +S+I ++ L L +D + F ++NK + D Sbjct: 210 LHSILGAYTCYRPDVGYVQGMSFI---AAVLILNLDTADAFIAFSNLLNKPCQMAFFRVD 266 Query: 161 CSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDG 220 F F + + + P+L ++ +TPD Y ++W+ +L++ ++ IWD Sbjct: 267 HGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDV 326 Query: 221 YLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDI 272 + + + F F + ++ E ILT+ + +FL P L E++ Sbjct: 327 FCRDGEEFL--FRTALGILKLFEDILTKMDFI--HMAQFLTRLPEDLPAEEL 374 >gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] Length = 693 Score = 43.5 bits (101), Expect = 6e-04 Identities = 37/172 (21%), Positives = 77/172 (44%), Gaps = 13/172 (7%) Query: 107 IESVITFY-CKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNK-----YIPRD 160 + S++ Y C ++ Y +S+I ++ L L +D + F ++NK + D Sbjct: 490 LHSILGAYTCYRPDVGYVQGMSFI---AAVLILNLDTADAFIAFSNLLNKPCQMAFFRVD 546 Query: 161 CSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDG 220 F F + + + P+L ++ +TPD Y ++W+ +L++ ++ IWD Sbjct: 547 HGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDV 606 Query: 221 YLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDI 272 + + + F F + ++ E ILT+ + +FL P L E++ Sbjct: 607 FCRDGEEFL--FRTALGILKLFEDILTKMDFI--HMAQFLTRLPEDLPAEEL 654 >gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] Length = 693 Score = 43.5 bits (101), Expect = 6e-04 Identities = 37/172 (21%), Positives = 77/172 (44%), Gaps = 13/172 (7%) Query: 107 IESVITFY-CKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNK-----YIPRD 160 + S++ Y C ++ Y +S+I ++ L L +D + F ++NK + D Sbjct: 490 LHSILGAYTCYRPDVGYVQGMSFI---AAVLILNLDTADAFIAFSNLLNKPCQMAFFRVD 546 Query: 161 CSQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDG 220 F F + + + P+L ++ +TPD Y ++W+ +L++ ++ IWD Sbjct: 547 HGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDV 606 Query: 221 YLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDI 272 + + + F F + ++ E ILT+ + +FL P L E++ Sbjct: 607 FCRDGEEFL--FRTALGILKLFEDILTKMDFI--HMAQFLTRLPEDLPAEEL 654 >gi|34147456 TBC domain-containing protein kinase-like [Homo sapiens] Length = 830 Score = 43.1 bits (100), Expect = 8e-04 Identities = 50/191 (26%), Positives = 79/191 (41%), Gaps = 22/191 (11%) Query: 45 LPADLRAKVWKIALNVAGKGDSLASWDGI---LDLPEQNTIHKD---CLQFIDQLSVPEE 98 +P +R W L V +G A +D I +P I D C Q+ + LS PE Sbjct: 404 IPPLMRGLTWAALLGV--EGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEG 461 Query: 99 KAAELLLDIESVITFYCKSR-NIKYSTSLSWIHLLKPLVHLQLPRSDL-YNCFYAIMNKY 156 A V+ + S ++ Y L L P ++L L Y C A + KY Sbjct: 462 HAK-----FRRVLKAWVVSHPDLVYWQGLD--SLCAPFLYLNFNNEALAYACMSAFIPKY 514 Query: 157 IP----RDCSQKGRPF-HLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCST 211 + +D S + + +F +I +H+PEL ++L+ PD YA+ W ++F Sbjct: 515 LYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPL 574 Query: 212 EVTQAIWDGYL 222 +WD L Sbjct: 575 HKIFHLWDTLL 585 >gi|68299759 ecotropic viral integration site 5 [Homo sapiens] Length = 810 Score = 38.5 bits (88), Expect = 0.021 Identities = 41/214 (19%), Positives = 89/214 (41%), Gaps = 22/214 (10%) Query: 45 LPADLRAKVWKIALNVAGKGDSLASWDGILDL-----PEQNTIHKDCLQFIDQLSVPEEK 99 +P RA VW++ + S+ D +L P + I +D + + + +EK Sbjct: 164 IPHHFRAIVWQLLCSA----QSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEK 219 Query: 100 AA---ELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNKY 156 + E+L ++ + R + Y ++I L+ +Q+P + + F +M Y Sbjct: 220 DSLGQEVLFNVMKAYSLV--DREVGYCQGSAFI---VGLLLMQMPEEEAFCVFVKLMQDY 274 Query: 157 IPRDC-----SQKGRPFHLFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCST 211 R+ ++ G + F +IQ H PEL + ++ YA +W ++F Sbjct: 275 RLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPL 334 Query: 212 EVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVI 245 + I+D ++ + + ++ +N E++ Sbjct: 335 PIATRIFDIFMSEGLEIVFRVGLALLQMNQAELM 368 >gi|22507409 TBC1 domain family, member 22A [Homo sapiens] Length = 517 Score = 37.0 bits (84), Expect = 0.061 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 5/109 (4%) Query: 174 LIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPF--FIY 231 L+ + ++ +LD ++ +A W+ +L T +WD Y + D F F Sbjct: 395 LVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHL 454 Query: 232 FLMLIILVNAKEVILTQESDSKEEVIKFLENTPSS-LNIEDIEDLFSLA 279 ++ LV ++ IL E +E++ FL+N P++ + EDI L + A Sbjct: 455 YVCAAFLVRWRKEIL--EEKDFQELLLFLQNLPTAHWDDEDISLLLAEA 501 >gi|229577000 ecotropic viral integration site 5-like isoform 1 [Homo sapiens] Length = 805 Score = 35.0 bits (79), Expect = 0.23 Identities = 22/116 (18%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Query: 135 LVHLQLPRSDLYNCFYAIMNKYIPRDC-----SQKGRPFHLFRLLIQYHEPELCSYLDTK 189 L+ +Q+P + + F +M +Y R+ ++ G + F ++Q P+L ++ ++ Sbjct: 205 LLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQ 264 Query: 190 KITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVI 245 YA +W +LF V ++D ++ + + ++ VN E++ Sbjct: 265 SFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELM 320 >gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo sapiens] Length = 794 Score = 35.0 bits (79), Expect = 0.23 Identities = 22/116 (18%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Query: 135 LVHLQLPRSDLYNCFYAIMNKYIPRDC-----SQKGRPFHLFRLLIQYHEPELCSYLDTK 189 L+ +Q+P + + F +M +Y R+ ++ G + F ++Q P+L ++ ++ Sbjct: 205 LLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQ 264 Query: 190 KITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVI 245 YA +W +LF V ++D ++ + + ++ VN E++ Sbjct: 265 SFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELM 320 >gi|13375952 TBC1 domain family, member 17 [Homo sapiens] Length = 648 Score = 35.0 bits (79), Expect = 0.23 Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 7/180 (3%) Query: 96 PEEKAAELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMNK 155 PE LL DI ++T+ ++ Y +S LL P++++ D + CF M Sbjct: 392 PENPGLGLLNDI--LLTYCMYHFDLGYVQGMS--DLLSPILYVIQNEVDAFWCFCGFMEL 447 Query: 156 YIPR-DCSQKGRPFHLFRLLIQYH--EPELCSYLDTKKITPDSYALNWLGSLFACYCSTE 212 + SQ+ L RLL+ +P LC +LD++ + WL F Sbjct: 448 VQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFP 507 Query: 213 VTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDI 272 +W+ ++ L+ +++ + L E++K + L++ED+ Sbjct: 508 DVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDV 567 >gi|221139907 TBC1 domain family, member 7 isoform a [Homo sapiens] Length = 293 Score = 34.7 bits (78), Expect = 0.30 Identities = 56/282 (19%), Positives = 96/282 (34%), Gaps = 37/282 (13%) Query: 19 EKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGILDLPE 78 +K LE L+ D E L Q PLP+ RA VWK+ L + LP Sbjct: 25 KKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVWKVLLGI---------------LPP 69 Query: 79 QNTIHKDCL-----QFIDQLSVPEEKAAELLLDIESVITFYCK-----SRNIKYSTSLS- 127 + H + Q++D L K + D Y + S + S S Sbjct: 70 HHESHAKVMMYRKEQYLDVLHA--LKVVRFVSDATPQAEVYLRMYQLESGKLPRSPSFPL 127 Query: 128 ------WIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEPE 181 ++ + K + + D Y +N+ + + F + + Sbjct: 128 EPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGR 187 Query: 182 LCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNA 241 L ++L P W FA Q +WD + + ++ + I+L Sbjct: 188 LLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFK 247 Query: 242 KEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYC 283 +V+ +S E++ KFLEN P + + L +C Sbjct: 248 IKVMAL---NSAEKITKFLENIPQDSSDAIVSKAIDLWHKHC 286 >gi|221139904 TBC1 domain family, member 7 isoform a [Homo sapiens] Length = 293 Score = 34.7 bits (78), Expect = 0.30 Identities = 56/282 (19%), Positives = 96/282 (34%), Gaps = 37/282 (13%) Query: 19 EKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGILDLPE 78 +K LE L+ D E L Q PLP+ RA VWK+ L + LP Sbjct: 25 KKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVWKVLLGI---------------LPP 69 Query: 79 QNTIHKDCL-----QFIDQLSVPEEKAAELLLDIESVITFYCK-----SRNIKYSTSLS- 127 + H + Q++D L K + D Y + S + S S Sbjct: 70 HHESHAKVMMYRKEQYLDVLHA--LKVVRFVSDATPQAEVYLRMYQLESGKLPRSPSFPL 127 Query: 128 ------WIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEPE 181 ++ + K + + D Y +N+ + + F + + Sbjct: 128 EPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGR 187 Query: 182 LCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNA 241 L ++L P W FA Q +WD + + ++ + I+L Sbjct: 188 LLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFK 247 Query: 242 KEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYC 283 +V+ +S E++ KFLEN P + + L +C Sbjct: 248 IKVMAL---NSAEKITKFLENIPQDSSDAIVSKAIDLWHKHC 286 >gi|7706041 TBC1 domain family, member 7 isoform a [Homo sapiens] Length = 293 Score = 34.7 bits (78), Expect = 0.30 Identities = 56/282 (19%), Positives = 96/282 (34%), Gaps = 37/282 (13%) Query: 19 EKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGILDLPE 78 +K LE L+ D E L Q PLP+ RA VWK+ L + LP Sbjct: 25 KKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVWKVLLGI---------------LPP 69 Query: 79 QNTIHKDCL-----QFIDQLSVPEEKAAELLLDIESVITFYCK-----SRNIKYSTSLS- 127 + H + Q++D L K + D Y + S + S S Sbjct: 70 HHESHAKVMMYRKEQYLDVLHA--LKVVRFVSDATPQAEVYLRMYQLESGKLPRSPSFPL 127 Query: 128 ------WIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEPE 181 ++ + K + + D Y +N+ + + F + + Sbjct: 128 EPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGR 187 Query: 182 LCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNA 241 L ++L P W FA Q +WD + + ++ + I+L Sbjct: 188 LLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFK 247 Query: 242 KEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYC 283 +V+ +S E++ KFLEN P + + L +C Sbjct: 248 IKVMAL---NSAEKITKFLENIPQDSSDAIVSKAIDLWHKHC 286 >gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] Length = 828 Score = 34.3 bits (77), Expect = 0.39 Identities = 47/251 (18%), Positives = 94/251 (37%), Gaps = 43/251 (17%) Query: 37 RNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGIL--------------DLPEQNTI 82 R I +G PL LR +VW + L + + L DL + N Sbjct: 95 RRIYKGIPL--QLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDL-DVNRT 151 Query: 83 HKDCLQFIDQLSVPEEKAAELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPR 142 +D + F D+ V ++ F+ + Y+T + + + + L L Sbjct: 152 FRDHIMFRDRYGVKQQSL------------FHVLAAYSIYNTEVGYCQGMSQITALLLMY 199 Query: 143 SDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHE----------PELCSYLDTKKIT 192 + + F+A++ + + G F L+++ E +L +LD+++I Sbjct: 200 MNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIY 259 Query: 193 PDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDS 252 Y + W F + IWD Y+ + + I+ ++ K ++ S Sbjct: 260 TSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL----S 315 Query: 253 KEEVIKFLENT 263 EE+++F + T Sbjct: 316 MEELVEFFQET 326 >gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] Length = 845 Score = 34.3 bits (77), Expect = 0.39 Identities = 47/251 (18%), Positives = 94/251 (37%), Gaps = 43/251 (17%) Query: 37 RNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGIL--------------DLPEQNTI 82 R I +G PL LR +VW + L + + L DL + N Sbjct: 112 RRIYKGIPL--QLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDL-DVNRT 168 Query: 83 HKDCLQFIDQLSVPEEKAAELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPR 142 +D + F D+ V ++ F+ + Y+T + + + + L L Sbjct: 169 FRDHIMFRDRYGVKQQSL------------FHVLAAYSIYNTEVGYCQGMSQITALLLMY 216 Query: 143 SDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHE----------PELCSYLDTKKIT 192 + + F+A++ + + G F L+++ E +L +LD+++I Sbjct: 217 MNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIY 276 Query: 193 PDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDS 252 Y + W F + IWD Y+ + + I+ ++ K ++ S Sbjct: 277 TSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKL----S 332 Query: 253 KEEVIKFLENT 263 EE+++F + T Sbjct: 333 MEELVEFFQET 343 >gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] Length = 381 Score = 34.3 bits (77), Expect = 0.39 Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 19/189 (10%) Query: 318 LAISVSEILQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHLD-SDLMLQNPSEFAQSV 376 +AIS + QL+ R ++DCRP E Y + H+ +A ++ +ML+ + V Sbjct: 14 MAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPV 73 Query: 377 KSLLEAQKQSIESGSIAGGEHLCFMGSGREE--EDMYMNMVLAHFLQKNKEYVSIA---S 431 ++L + G + + + E+ VL L+K K+ A Sbjct: 74 RALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLE 133 Query: 432 GGFMALQQHLA---DINVDG---------PENGYGHWIASTSGSRSSINSVDGESPNGSS 479 GGF Q + + N+DG P G G + +S S S I S PN ++ Sbjct: 134 GGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLG-GLRISSDSSSDIESDLDRDPNSAT 192 Query: 480 DRGMKSLVN 488 D L N Sbjct: 193 DSDGSPLSN 201 >gi|157388983 TBC1 domain family, member 19 [Homo sapiens] Length = 526 Score = 33.5 bits (75), Expect = 0.67 Identities = 47/220 (21%), Positives = 79/220 (35%), Gaps = 46/220 (20%) Query: 46 PADLRAKVWKIALNVAGKGDSLASWDGIL------DLPEQNTIHKDC------------- 86 P LRA++W + LN++ + + + ++ + DL + I+KD Sbjct: 253 PTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVF 312 Query: 87 --------LQFIDQLSV----------PEEKAAELLLDIESVITFYCKSRNIKYSTSLSW 128 L F SV P + L +E FY + I + + Sbjct: 313 EDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMY 372 Query: 129 IHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFH------LFRLLIQYHEPEL 182 + PL L S LY F + ++ R S P LF L+Q + P+L Sbjct: 373 V---APLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQL 429 Query: 183 CSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYL 222 +L P + W+ F+ Y +T+ +WD L Sbjct: 430 FYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRIL 469 >gi|13994322 TBC1 domain family, member 10A [Homo sapiens] Length = 508 Score = 33.5 bits (75), Expect = 0.67 Identities = 33/123 (26%), Positives = 47/123 (38%), Gaps = 13/123 (10%) Query: 138 LQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHL----FRLLIQYHEPELCSYLDTKKITP 193 + +P + C I KY+P S+K L L+Q P +L +KI P Sbjct: 208 MHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDP 267 Query: 194 DSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDSK 253 Y W F C S + W L+ D FF + +I V V+L S Sbjct: 268 LLYMTEW----FMCAFSRTLP---WSSVLRVWDMFFCEGVKIIFRVGL--VLLKHALGSP 318 Query: 254 EEV 256 E+V Sbjct: 319 EKV 321 >gi|119220552 sidekick 1 [Homo sapiens] Length = 2213 Score = 33.1 bits (74), Expect = 0.87 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 16/109 (14%) Query: 411 YMNMVLAHFLQKNKEYVSIASGGFMALQQHLADINVDGPENGYGHWIASTSGSRSSINSV 470 Y N + +E V++ +GGF AL+ +NV ST ++ S Sbjct: 2038 YKNCSTGKGISTMEESVTLDNGGFAALELSSRHLNV-----------KSTFSKKNGTRSP 2086 Query: 471 DGESPNG--SSDRGMKSLVNKMTVALKTKSVNVREKVISFIENTSTPVD 517 SP G SD + + NK A+ T+SV+++EK E+ +T D Sbjct: 2087 PRPSPGGLHYSD---EDICNKYNGAVLTESVSLKEKSADASESEATDSD 2132 >gi|23397642 GREB1 protein isoform a [Homo sapiens] Length = 1949 Score = 33.1 bits (74), Expect = 0.87 Identities = 25/60 (41%), Positives = 32/60 (53%), Gaps = 2/60 (3%) Query: 259 FLENTPSSLNIEDIEDLFS-LAQYYC-SKTPASFRKDNHHLFGSTLLGIKDDDADLSQAL 316 ++ + P SLNI + LFS L Y C S ASF K H L G+TL I D + L Q + Sbjct: 1854 YVSSRPHSLNISCSDLLFSGLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRSSLRQTV 1913 >gi|29648315 small G protein signaling modulator 3 [Homo sapiens] Length = 749 Score = 33.1 bits (74), Expect = 0.87 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 6/110 (5%) Query: 170 LFRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFF 229 L L++QY P L L I L+W + FA ++ IWD + + Sbjct: 251 LRHLIVQYL-PRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSR-- 307 Query: 230 IYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLA 279 + F + + +++ KE L Q S++ + L + PS + ED E L +A Sbjct: 308 VLFQLTLGMLHLKEEELIQ-SENSASIFNTLSDIPSQM--EDAELLLGVA 354 >gi|167614488 TBC1 domain family, member 10B [Homo sapiens] Length = 808 Score = 32.7 bits (73), Expect = 1.1 Identities = 49/241 (20%), Positives = 84/241 (34%), Gaps = 21/241 (8%) Query: 45 LPADLRAKVWKIALNVA-------GKGDSLASWDGI---LDLPEQNTIHKDCLQFIDQLS 94 +P+ LRAK W+ N GK + L G LD+ E++ +H+ F + + Sbjct: 361 IPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKD-LHRQ-FPFHEMFA 418 Query: 95 VPEEKAAELLLDIESVITFYCKSRNIKYSTSLSWIHLLKPLVHLQLPRSDLYNCFYAIMN 154 + L I T Y + + LL + +P + C I + Sbjct: 419 ARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLL-----MHMPAEQAFWCLVQICD 473 Query: 155 KYIPRDCSQKGRPFHL----FRLLIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCS 210 KY+P S L F L++ P +L ++I P Y W +FA Sbjct: 474 KYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLP 533 Query: 211 TEVTQAIWDGYLQQADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIE 270 +WD + + ++++ V + E ++ L N P E Sbjct: 534 WASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQE 593 Query: 271 D 271 D Sbjct: 594 D 594 >gi|125625350 cell division cycle 25C isoform a [Homo sapiens] Length = 473 Score = 31.6 bits (70), Expect = 2.5 Identities = 16/43 (37%), Positives = 24/43 (55%) Query: 326 LQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQN 368 L + + QG +F+V+DCR +Y GH+ A +L S L N Sbjct: 313 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFN 355 >gi|12408658 cell division cycle 25C isoform b [Homo sapiens] Length = 400 Score = 31.6 bits (70), Expect = 2.5 Identities = 16/43 (37%), Positives = 24/43 (55%) Query: 326 LQANQLQGEGVRFFVVDCRPAEQYNAGHLSTAFHLDSDLMLQN 368 L + + QG +F+V+DCR +Y GH+ A +L S L N Sbjct: 240 LLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFN 282 >gi|16975496 cortactin binding protein 2 [Homo sapiens] Length = 1663 Score = 31.6 bits (70), Expect = 2.5 Identities = 18/71 (25%), Positives = 38/71 (53%) Query: 224 QADPFFIYFLMLIILVNAKEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYC 283 + D F +L + +++ +I ++S SK+++I LEN S E + D + + Sbjct: 1161 EVDAGFSKEQLLDLFISSACLIPVKQSPSKKKIIIILENLEKSSLSELLRDFLAPLENRS 1220 Query: 284 SKTPASFRKDN 294 +++P +F+K N Sbjct: 1221 TESPCTFQKGN 1231 >gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens] Length = 817 Score = 31.2 bits (69), Expect = 3.3 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 174 LIQYHEPELCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGY------LQQADP 227 L++ H+ EL +L+ +I P Y L W+ LF + +WD L D Sbjct: 308 LLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDY 367 Query: 228 FFIYFLMLI 236 F+ L+ I Sbjct: 368 IFVAMLLYI 376 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,760,669 Number of Sequences: 37866 Number of extensions: 1146999 Number of successful extensions: 3288 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 3247 Number of HSP's gapped (non-prelim): 60 length of query: 684 length of database: 18,247,518 effective HSP length: 109 effective length of query: 575 effective length of database: 14,120,124 effective search space: 8119071300 effective search space used: 8119071300 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.