Search of human proteins with 21630277

Search of human proteins with 21630277

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21630277 tripartite motif-containing 11 [Homo sapiens]
         (468 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21630277 tripartite motif-containing 11 [Homo sapiens]             963   0.0  
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            381   e-106
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   381   e-106
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    381   e-106
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   374   e-103
gi|37622899 ring finger protein 137 [Homo sapiens]                    368   e-102
gi|5730009 ret finger protein [Homo sapiens]                          361   e-100
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   359   3e-99
gi|15208660 tripartite motif protein 21 [Homo sapiens]                352   3e-97
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   339   3e-93
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             324   9e-89
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              315   7e-86
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   305   6e-83
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   291   9e-79
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    290   1e-78
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    287   2e-77
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    287   2e-77
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            278   6e-75
gi|22749269 ring finger protein 129 [Homo sapiens]                    275   5e-74
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   268   1e-71
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      265   7e-71
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      265   7e-71
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   265   7e-71
gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi...   264   1e-70
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   262   4e-70
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...   257   2e-68
gi|210147600 tripartite motif-containing 64 [Homo sapiens]            254   9e-68
gi|20270353 tripartite motif-containing 43 [Homo sapiens]             251   1e-66
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li...   244   1e-64
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...   243   4e-64

>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  963 bits (2490), Expect = 0.0
 Identities = 468/468 (100%), Positives = 468/468 (100%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60

Query: 61  PQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEH 120
           PQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEH
Sbjct: 61  PQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEH 120

Query: 121 WAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLG 180
           WAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLG
Sbjct: 121 WAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLG 180

Query: 181 EFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPA 240
           EFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPA
Sbjct: 181 EFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPA 240

Query: 241 LGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPEL 300
           LGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPEL
Sbjct: 241 LGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPEL 300

Query: 301 ILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCR 360
           ILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCR
Sbjct: 301 ILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCR 360

Query: 361 ENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSA 420
           ENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSA
Sbjct: 361 ENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSA 420

Query: 421 TDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLAPQ 468
           TDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLAPQ
Sbjct: 421 TDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLAPQ 468


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  381 bits (979), Expect = e-106
 Identities = 211/464 (45%), Positives = 281/464 (60%), Gaps = 15/464 (3%)

Query: 10  LQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPECRELSPQRNL 65
           L+E+A C +CLD+  +PV  DCGH+FC  CI     +  G   G YACP+CR        
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69

Query: 66  RPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRV 125
           RPNR LA + E  RRL   +      C  H E L+ FC ++   LC  C+   EH  HR 
Sbjct: 70  RPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTHRT 129

Query: 126 RPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERL 185
            PLQ+AA   + KL+ +LE +RK+++DAL  +A   +  V+W++ VE QRQ    EFE+ 
Sbjct: 130 APLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKH 189

Query: 186 RRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQ 245
           R  LA+EEQ+ L+RLE EE   L RLRE  + L QQS  L EL  EL+ RCQ PALGLL+
Sbjct: 190 RGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGLLE 249

Query: 246 DIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSED 305
            ++  L R + V     E +PMEL+T C +PG  E LR+F+ DV LDP TA+P L+L+ D
Sbjct: 250 GVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLTAD 309

Query: 306 RRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNR 365
            RSVQ G+  + +P++PERFD  PC+LG + F+SGRHYWEV VG+   W LGVC++ + R
Sbjct: 310 LRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPR 369

Query: 366 KEKGELSAGNGFWILVFL-GSYYNSSERALAPL--RDPPRRVGIFLDYEAGHLSFYSATD 422
           K +   S  NG W L  L G+ Y        PL   + PR +GIFLDYEAG +SFY+ TD
Sbjct: 370 KGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTD 429

Query: 423 GSLLFIFPEIPFSGTLRPLFSPLSSSP---TPMTICRPKGGSGD 463
           GS ++ F ++ FSG LRP F    ++P    P TI     GSG+
Sbjct: 430 GSYIYTFNQL-FSGLLRPYFFICDATPLILPPTTI----AGSGN 468


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  381 bits (978), Expect = e-106
 Identities = 214/465 (46%), Positives = 281/465 (60%), Gaps = 32/465 (6%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP---------EGPY 51
           M A +L+  LQEEATC+ICLDYFTDPVMT CGHNFCR CI+  W +          +G +
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 52  ACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLC 111
            CPECRE+SPQRNL PNR L K+AEMA++   P    Q +C  H EPL  FC  +   +C
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118

Query: 112 AACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMV 171
             C  S EH  HRV P ++A +  K KLE+ +E+LR+Q+      QA+ +++   WQ  V
Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178

Query: 172 ESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAE 231
           + +R+ ++ EFE++   L EEEQ+LLQ LE EE E   RLRE  A L +Q   L  L+ +
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 232 LEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVV-PMELRTVCRVPGLVETLRRFRGDVT 290
           LE R     L +LQD+K+ L R  +V +Q PEV  P   RTVCRVPG +E LR F  DV 
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVV 298

Query: 291 LDPDTANPELILSEDRRSVQRGDLRQALPDSPE--------RFDPGPCVLGQERFTSGRH 342
            D  +A P L+L E R+       R+ L  SPE        RF   PC +GQ  F+SGRH
Sbjct: 299 PDATSAYPYLLLYESRQ-------RRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRH 351

Query: 343 YWEV--EVGDRTSWALGVCRENVNRKEKGELSAGNGFWIL-VFLGSYYNSSERALAP--L 397
           YWEV   +     WALGVCR+NV+RK++      NGFW++ +  G+ Y S+  AL P  L
Sbjct: 352 YWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVML 411

Query: 398 RDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF 442
            +PP  +GIFLD+EAG +SFYS +DGS L  + +  F G L+P F
Sbjct: 412 MEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFF 456


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  381 bits (978), Expect = e-106
 Identities = 214/465 (46%), Positives = 281/465 (60%), Gaps = 32/465 (6%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP---------EGPY 51
           M A +L+  LQEEATC+ICLDYFTDPVMT CGHNFCR CI+  W +          +G +
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 52  ACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLC 111
            CPECRE+SPQRNL PNR L K+AEMA++   P    Q +C  H EPL  FC  +   +C
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118

Query: 112 AACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMV 171
             C  S EH  HRV P ++A +  K KLE+ +E+LR+Q+      QA+ +++   WQ  V
Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178

Query: 172 ESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAE 231
           + +R+ ++ EFE++   L EEEQ+LLQ LE EE E   RLRE  A L +Q   L  L+ +
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 232 LEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVV-PMELRTVCRVPGLVETLRRFRGDVT 290
           LE R     L +LQD+K+ L R  +V +Q PEV  P   RTVCRVPG +E LR F  DV 
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVV 298

Query: 291 LDPDTANPELILSEDRRSVQRGDLRQALPDSPE--------RFDPGPCVLGQERFTSGRH 342
            D  +A P L+L E R+       R+ L  SPE        RF   PC +GQ  F+SGRH
Sbjct: 299 PDATSAYPYLLLYESRQ-------RRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRH 351

Query: 343 YWEV--EVGDRTSWALGVCRENVNRKEKGELSAGNGFWIL-VFLGSYYNSSERALAP--L 397
           YWEV   +     WALGVCR+NV+RK++      NGFW++ +  G+ Y S+  AL P  L
Sbjct: 352 YWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVML 411

Query: 398 RDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF 442
            +PP  +GIFLD+EAG +SFYS +DGS L  + +  F G L+P F
Sbjct: 412 MEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFF 456


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  374 bits (959), Expect = e-103
 Identities = 205/449 (45%), Positives = 284/449 (63%), Gaps = 16/449 (3%)

Query: 9   NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
           NLQ EA+C++CL+Y  +PV+ +CGHNFC+ CI R W   E  + CP CR+ S  R+LRPN
Sbjct: 22  NLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPN 81

Query: 69  RPLAKMAEMARRLHPPSPV--PQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVR 126
           R L  M E+A++L         + +CP H E L+ FC ++   +C  C  S  H AH V 
Sbjct: 82  RQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVV 141

Query: 127 PLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLR 186
           PL DA ++ K KL+K LE L +++Q+    ++  ++     +++VES+RQ +L EFE L 
Sbjct: 142 PLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELH 201

Query: 187 RLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQD 246
           R L EE+Q LL RLEEEE ++L RLRE AAHLG +   LA L AE+EG+C      +L+D
Sbjct: 202 RRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKD 261

Query: 247 IKDALRRVQDVKLQPPEVVPMEL-RTVCRVP----GLVETLRRFRGDVTLDPDTANPELI 301
           +K  L + + VK      V +EL +     P     L + L++   DVTLDP+TA+P L+
Sbjct: 262 VKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLV 321

Query: 302 LSEDRRSVQRGDLR-QALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCR 360
           LSEDR+SV+  + R + LPD+P RF   PCVL  E FTSGRHYWEVEVGD+T WA+GVCR
Sbjct: 322 LSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCR 381

Query: 361 ENVNRKEKGELS--AGNGFW-ILVFLGSYYNSSERALAPL--RDPPRRVGIFLDYEAGHL 415
           ++V+R  KGEL+     G+W + ++ G  Y ++     PL  +  P+RVGIFLDYEAG L
Sbjct: 382 DSVSR--KGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTL 439

Query: 416 SFYSATDGSLLFIFPEIPFSGTLRPLFSP 444
           SFY+ TD S ++ F +  F+  L PLF P
Sbjct: 440 SFYNVTDRSHIYTFTD-TFTEKLWPLFYP 467


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  368 bits (944), Expect = e-102
 Identities = 205/472 (43%), Positives = 280/472 (59%), Gaps = 24/472 (5%)

Query: 12  EEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP----EGPYACPECRELSPQRNLRP 67
           EE  C IC+ +  +P+  DCGH+FC  C+   W  P       Y CP CR     RNLRP
Sbjct: 12  EEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNLRP 71

Query: 68  NRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRV 125
           N  LA + E  R  RLHP   +   +C  H E L  FC +++ ++C AC +S EH AH V
Sbjct: 72  NWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAHSV 131

Query: 126 RPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERL 185
            P++D A + K +L ++LEHL+K+ ++A   +    +    W+  VE+++Q+++ EFE+ 
Sbjct: 132 VPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFEKY 191

Query: 186 RRLLAEEE---QQL-------LQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGR 235
           +RLL +++   +QL       L  L+ E  E + +L    + L QQS  L  +IAEL+ R
Sbjct: 192 QRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELKER 251

Query: 236 CQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDT 295
            Q P   +LQDI++ L R +   LQ PE + +EL+T CRV GL E L+ +  DV LDPDT
Sbjct: 252 SQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILKTYAADVRLDPDT 311

Query: 296 ANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWA 355
           A   LI+SEDR+ V  GD  Q LPD+PERF     VLG +  +SGRHYWEVEVGDR+ W 
Sbjct: 312 AYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWG 371

Query: 356 LGVCRENVNRKEKGELSAGNGFWIL-VFLGSYY--NSSERALAPLRDPPRRVGIFLDYEA 412
           LGVC++NV+RKE   LS   GFW++ +  G+ Y   + E  +  L  PPRRVGIF+DYEA
Sbjct: 372 LGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEA 431

Query: 413 GHLSFYSATD-GSLLFIFPEIPFSGTLRPLFSPLSSSPT----PMTICRPKG 459
             +SFY+ TD GS +F FP  PF G L P FSP  S  T    P+ IC   G
Sbjct: 432 HDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTAPLAICSLDG 483


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  361 bits (926), Expect = e-100
 Identities = 196/497 (39%), Positives = 278/497 (55%), Gaps = 35/497 (7%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           MA+  ++  LQ+E TC +CL YF +P+M DCGHN C  C+ RCWG  E   +CP+CRE  
Sbjct: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60

Query: 61  PQRNLRPNRPLAKMAEMARRLHPPSPV----PQGVCPAHREPLAAFCGDELRLLCAACER 116
           PQR++RPNR LA + ++ ++L    P       GVC  HREPL  +C ++   +C  C+R
Sbjct: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120

Query: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176
           S EH  H V PL++A E  K +++  L+HL++        +AQ ++       + + +R+
Sbjct: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180

Query: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236
            ++ EFE+L   L E E +LL RLEE +L +   +           +HL+ LIA+LE + 
Sbjct: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240

Query: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPG-----LVETLRRFRG---- 287
           Q P   LLQDI D L R + +++  P + P +L+    +       L E+L++F      
Sbjct: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300

Query: 288 ----------------DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCV 331
                           DVTLDPDTA P LILS++ R V+   L+Q LPD+PERF+  PCV
Sbjct: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360

Query: 332 LGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFW-ILVFLGSYY--N 388
           LG   F +GRHYWEVEVGD+  W +GVC ++V RK     +  NGFW + ++ G  Y   
Sbjct: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420

Query: 389 SSERALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSS- 447
           +S     PLR P +RVGIFLDY+AG +SFY+ T+    F F    F G +RP FS   S 
Sbjct: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG 480

Query: 448 --SPTPMTICRPKGGSG 462
             S  P+ IC   G  G
Sbjct: 481 GKSAAPLIICPMSGIDG 497


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  359 bits (921), Expect = 3e-99
 Identities = 206/479 (43%), Positives = 284/479 (59%), Gaps = 46/479 (9%)

Query: 9   NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
           NLQ EA+C++CL+Y  +PV+ +CGHNFC+ CI R W   E  + CP CR+ S  R+LRPN
Sbjct: 22  NLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPN 81

Query: 69  RPLAKMAEMARRLHPPSPV--PQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVR 126
           R L  M E+A++L         + +CP H E L+ FC ++   +C  C  S  H AH V 
Sbjct: 82  RQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVV 141

Query: 127 PLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLR 186
           PL DA ++ K KL+K LE L +++Q+    ++  ++     +++VES+RQ +L EFE L 
Sbjct: 142 PLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELH 201

Query: 187 RLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQD 246
           R L EE+Q LL RLEEEE ++L RLRE AAHLG +   LA L AE+EG+C      +L+D
Sbjct: 202 RRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKD 261

Query: 247 IKDALR------------------------------RVQDVKLQPPEVVPMEL-RTVCRV 275
           +K  L                               R + VK      V +EL +     
Sbjct: 262 VKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNF 321

Query: 276 P----GLVETLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLR-QALPDSPERFDPGPC 330
           P     L + L++   DVTLDP+TA+P L+LSEDR+SV+  + R + LPD+P RF   PC
Sbjct: 322 PRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPC 381

Query: 331 VLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELS--AGNGFW-ILVFLGSYY 387
           VL  E FTSGRHYWEVEVGD+T WA+GVCR++V+R  KGEL+     G+W + ++ G  Y
Sbjct: 382 VLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSR--KGELTPLPETGYWRVRLWNGDKY 439

Query: 388 NSSERALAPL--RDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSP 444
            ++     PL  +  P+RVGIFLDYEAG LSFY+ TD S ++ F +  F+  L PLF P
Sbjct: 440 AATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTD-TFTEKLWPLFYP 497


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  352 bits (904), Expect = 3e-97
 Identities = 205/471 (43%), Positives = 281/471 (59%), Gaps = 12/471 (2%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           MA+    T + EE TC ICLD F +PV  +CGH+FC+ECI +      G   CP CR+  
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVG--KGGGSVCPVCRQRF 58

Query: 61  PQRNLRPNRPLAKMAEMARRLHPPSPV-PQGV-CPAHREPLAAFCGDELRLLCAACERSG 118
             +NLRPNR LA M    + +   +    QG  C  H E L  FC  + + LC  C +S 
Sbjct: 59  LLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSR 118

Query: 119 EHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNV 178
           +H  H + PL++AA++ + KL+ +L  LR++ + A   + +       W+K VE+Q+  +
Sbjct: 119 KHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRI 178

Query: 179 LGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQL 238
             EF + +  L EEEQ+ LQ LE++E E L  L E  A L QQS  L ELI+EL+ RC  
Sbjct: 179 HAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHS 238

Query: 239 PALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANP 298
            AL LLQ++   L R +   L+  ++   ELR+VC VPGL + LR     +TLDPDTANP
Sbjct: 239 SALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANP 298

Query: 299 ELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGV 358
            LILSEDRR V+ GD +Q++P + ERFD  P VLG + F SG+HYWEV+V  + +W LGV
Sbjct: 299 WLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGV 358

Query: 359 CRENVNRKEKGELSAGNGFW-ILVFLGSYYNSSERALAP--LRDPPRRVGIFLDYEAGHL 415
           CR++V RK    LS+ +GFW I ++    Y +      P  L+ PP +VGIFLDYEAG +
Sbjct: 359 CRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMV 418

Query: 416 SFYSATD-GSLLFIFPEIPFSGTLRPLFSP----LSSSPTPMTICRPKGGS 461
           SFY+ TD GSL++ F E  F+G LRP FSP       +  P+T+C    GS
Sbjct: 419 SFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGS 469


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  339 bits (870), Expect = 3e-93
 Identities = 194/438 (44%), Positives = 258/438 (58%), Gaps = 32/438 (7%)

Query: 28  MTDCGHNFCRECIRRCWGQP---------EGPYACPECRELSPQRNLRPNRPLAKMAEMA 78
           MT CGHNFCR CI+  W +          +G + CPECRE+SPQRNL PNR L K+AEMA
Sbjct: 1   MTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMA 60

Query: 79  RRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAK 138
           ++   P    Q +C  H EPL  FC  +   +C  C  S EH  HRV P ++A +  K K
Sbjct: 61  QQ--HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLK 118

Query: 139 LEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQ 198
           LE+ +E+LR+Q+      QA+ +++   WQ  V+ +R+ ++ EFE++   L EEEQ+LLQ
Sbjct: 119 LEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQ 178

Query: 199 RLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVK 258
            LE EE E   RLRE  A L +Q   L  L+ +LE R     L +LQD+K+ L R  +V 
Sbjct: 179 ALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVS 238

Query: 259 LQPPEVV-PMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQA 317
           +Q PEV  P   RTVCRVPG +E LR F  DV  D  +A P L+L E R+       R+ 
Sbjct: 239 VQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQ-------RRY 291

Query: 318 LPDSPE--------RFDPGPCVLGQERFTSGRHYWEV--EVGDRTSWALGVCRENVNRKE 367
           L  SPE        RF   PC +GQ  F+SGRHYWEV   +     WALGVCR+NV+RK+
Sbjct: 292 LGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKD 351

Query: 368 KGELSAGNGFWIL-VFLGSYYNSSERALAP--LRDPPRRVGIFLDYEAGHLSFYSATDGS 424
           +      NGFW++ +  G+ Y S+  AL P  L +PP  +GIFLD+EAG +SFYS +DGS
Sbjct: 352 RVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGS 411

Query: 425 LLFIFPEIPFSGTLRPLF 442
            L  + +  F G L+P F
Sbjct: 412 HLHTYSQATFPGPLQPFF 429


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  324 bits (831), Expect = 9e-89
 Identities = 185/466 (39%), Positives = 272/466 (58%), Gaps = 15/466 (3%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           M+  DL  NL+EE TC ICLDYF+ PV T+CGH+FC  C+ R W +   P +CPEC    
Sbjct: 1   MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTL 60

Query: 61  PQRNLRPNRPLAKMAEMARRLHPP---SPVPQGVCPAHREPLAAFCGDELRLLCAACERS 117
              + + N  L ++A +AR+L      S   QG          A   DE        +  
Sbjct: 61  EGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQ-- 118

Query: 118 GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQN 177
             H A+RV    +A E  + KL++ L  LR + ++A        E   L Q+  ++ +Q 
Sbjct: 119 -SHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQV 177

Query: 178 VLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQ 237
           V+ E+ ++ + L EEEQ  LQ LE+EE E + +LR     L QQ   L+++IA++E   Q
Sbjct: 178 VVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQ 237

Query: 238 LPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTAN 297
             A   L++++ AL R + + LQ PE    EL ++CR+ G+ E LR+F  ++TLDP TAN
Sbjct: 238 SSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGMKEMLRKFSTEITLDPATAN 296

Query: 298 PELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALG 357
             L+LSED +SV+ G  RQ LPD+PERFD    VLG + FTSGRHYWEVEVG++T W +G
Sbjct: 297 AYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVG 356

Query: 358 VCRENVNRKEKGELSAGNGFWIL-VFLGSYYN---SSERALAPLRDPPRRVGIFLDYEAG 413
           +C+++V+RK       G+ F ++ + +G  Y+   SS      +R+P  +VG+FLDYE+G
Sbjct: 357 ICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESG 416

Query: 414 HLSFYSATDGSLLFIFPEIPFSGTLRPLFSPL----SSSPTPMTIC 455
           H++FY+ TD SL++ FP+  F   LRP+FSP      ++  P+TIC
Sbjct: 417 HIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTIC 462


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  315 bits (806), Expect = 7e-86
 Identities = 189/463 (40%), Positives = 253/463 (54%), Gaps = 20/463 (4%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP------EGPYACP 54
           MA+   +  + EEATC+ICL   T+PV  +CGH++C  CI   +  P      +  + CP
Sbjct: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60

Query: 55  ECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114
           +CR      +LRPN+ L  + E  +            C  H E    FC DE +L+C  C
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-----CEEHGEQFHLFCEDEGQLICWRC 115

Query: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVL-WQKMVES 173
           ER+ +H  H    ++D  +  K KL+K++  L KQ++D    Q  +    +  W++ V+ 
Sbjct: 116 ERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLEDRCTEQKLSTAMRITKWKEKVQI 174

Query: 174 QRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE 233
           QRQ +  +F+ L+  L EEE+  L RLE+EE + L RLR+  A LG +S  L   I ELE
Sbjct: 175 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE 234

Query: 234 GRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLV----ETLRRFRGDV 289
            +CQ  A  LLQ++ D L R   VKL+  E V +EL T+C V  L     + LR  +  V
Sbjct: 235 EKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSV 294

Query: 290 TLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVG 349
           TLDPDTA+ ELILSEDRR V RG  ++    S  RF   PCVLG E FTSGR Y+EV+VG
Sbjct: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG 354

Query: 350 DRTSWALGVCRENVNRKEKGELSAGNGFWILVFL---GSYYNSSERALAPLRDPPRRVGI 406
           + T W LGVC ENV R    +    +GFW L      G    +S      L + P  VGI
Sbjct: 355 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI 414

Query: 407 FLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSP 449
           FLDYEAG +SFY+   G  +F FP+  FS TLRP F     SP
Sbjct: 415 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSP 457


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  305 bits (781), Expect = 6e-83
 Identities = 185/469 (39%), Positives = 253/469 (53%), Gaps = 31/469 (6%)

Query: 9   NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
           ++QEE TC ICLDYF DPV  +CGHNFCR C+ R W    GP+ CPECR  S    LRPN
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64

Query: 69  RPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPL 128
             LA++ E  +R     PVP G+C  H EPL  FC D+ R +C  C  S EH  H + P+
Sbjct: 65  WALARLTEKTQRRRL-GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123

Query: 129 QDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRL 188
            +A E  + KL KS  +L  +M+  +  Q    +    W+  ++SQR  +  EF +L   
Sbjct: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 183

Query: 189 LAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIK 248
           L EEE   LQRL +EE E   +L E    L Q  A L +LI E+  + Q P L LLQ+ K
Sbjct: 184 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPK 243

Query: 249 DALRR--VQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSEDR 306
           + L R  +QDV      +  ++++TVC++P + E L+RF+  V L  DTA+P+L+ S++ 
Sbjct: 244 EVLTRSEIQDVNY---SLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG 300

Query: 307 RSVQRGDLRQALP------------DSP------ERFDPGPCVLGQERFTSGRHYWEVEV 348
           R V+      + P             +P      ERF   PCVLG+  FTSG+HYWEVE 
Sbjct: 301 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES 360

Query: 349 GDRTSWALGVCRENV-NRKEKGELSAGNGFWILVF-LGSYYNSSERALAPLRDPP--RRV 404
            D    A+GVCRE+V    ++ ++S   G W + +    Y+        P +  P   RV
Sbjct: 361 RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV 420

Query: 405 GIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF--SPLSSSPTP 451
           G++LD   G++SFYSA DG  L  F     S  LRP F  SPL+S   P
Sbjct: 421 GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFWLSPLASLVIP 468


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  291 bits (745), Expect = 9e-79
 Identities = 185/495 (37%), Positives = 253/495 (51%), Gaps = 57/495 (11%)

Query: 9   NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
           ++QEE TC ICLDYF DPV  +CGHNFCR C+ R W    GP+ CPECR  S    LRPN
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64

Query: 69  RPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPL 128
             LA++ E  +R     PVP G+C  H EPL  FC D+ R +C  C  S EH  H + P+
Sbjct: 65  WALARLTEKTQR-RRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123

Query: 129 QDAAEDLKA--------------------------KLEKSLEHLRKQMQDALLFQAQADE 162
            +A E  +                           KL KS  +L  +M+  +  Q    +
Sbjct: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVK 183

Query: 163 TCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQS 222
               W+  ++SQR  +  EF +L   L EEE   LQRL +EE E   +L E    L Q  
Sbjct: 184 NATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTI 243

Query: 223 AHLAELIAELEGRCQLPALGLLQDIKDALRR--VQDVKLQPPEVVPMELRTVCRVPGLVE 280
           A L +LI E+  + Q P L LLQ+ K+ L R  +QDV      +  ++++TVC++P + E
Sbjct: 244 ASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNY---SLEAVKVKTVCQIPLMKE 300

Query: 281 TLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALP------------DSP------ 322
            L+RF+  V L  DTA+P+L+ S++ R V+      + P             +P      
Sbjct: 301 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 360

Query: 323 ERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENV-NRKEKGELSAGNGFWILV 381
           ERF   PCVLG+  FTSG+HYWEVE  D    A+GVCRE+V    ++ ++S   G W + 
Sbjct: 361 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 420

Query: 382 F-LGSYYNSSERALAPLRDPP--RRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTL 438
           +    Y+        P +  P   RVG++LD   G++SFYSA DG  L  F     S  L
Sbjct: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RL 479

Query: 439 RPLF--SPLSSSPTP 451
           RP F  SPL+S   P
Sbjct: 480 RPFFWLSPLASLVIP 494


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  290 bits (743), Expect = 1e-78
 Identities = 178/489 (36%), Positives = 249/489 (50%), Gaps = 51/489 (10%)

Query: 6   LSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEG------------PYAC 53
           L+  LQ EATC+ICL+ F +PV  +CGH+FCR CI RCW +P              P  C
Sbjct: 19  LAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPC 78

Query: 54  PECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVP-------------QGVCPAHREPLA 100
           P+CRE +    LRPNR LA +A + RR   P+  P                C  H EP  
Sbjct: 79  PQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFK 138

Query: 101 AFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQA 160
            +C D+ R +C  C+R+ EH  H V PL +A ++ K  LE  L  L+K+++D  +F++  
Sbjct: 139 LYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTE 198

Query: 161 DETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQ 220
            +      K + ++++ V  EF+ LR  L E+E +LL RLEE   EV  +  E  A LG 
Sbjct: 199 KKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGV 258

Query: 221 QSAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELR-----TVCRV 275
           +   L++L ++++   Q P L  LQ+ K  L R  +V    P  V  E++        + 
Sbjct: 259 EITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKT 318

Query: 276 PGLVETLRRFRGD------------VTLDPDTANPELILSEDRRSVQRGDLRQALPDSPE 323
             L   L++F+ D            +TLDPDTANP LILS D + V+ G+  Q LP+ P 
Sbjct: 319 FVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPC 378

Query: 324 RFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFL 383
           RFD    VL    F+SGRH+WEVEVG +  WA GV RE+V RK     +   G W L   
Sbjct: 379 RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLN 438

Query: 384 GSYYNSSERALAPLRDP-----PRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTL 438
           G  Y +     +P R P       RV + LD E G +SFY+  D   L+ F  + F   +
Sbjct: 439 GGQYWA---VTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTF-RVNFQERV 494

Query: 439 RPLFSPLSS 447
            PLFS  S+
Sbjct: 495 FPLFSVCST 503


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  287 bits (734), Expect = 2e-77
 Identities = 177/490 (36%), Positives = 266/490 (54%), Gaps = 37/490 (7%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56
           M +P L  +++EE TC ICL+  T+P+  DCGH+FC+ CI    R      EG  +CP C
Sbjct: 1   MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 59

Query: 57  RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114
           +      NLRPNR LA +    R   L P   +   +C  H E L  FC ++ +++C  C
Sbjct: 60  QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 119

Query: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174
           ERS EH  H    +++ A++ + K ++SL+ L+ + Q+A    A   E    W+  +E +
Sbjct: 120 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 179

Query: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234
           R  +  EF +LR +L   EQ+ L++LE+EE + L  + E    L  Q+  L ELI++LE 
Sbjct: 180 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 239

Query: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG------- 287
           RCQ   + LLQD+ D   R +   L+ PE +P +LR++ R P L   LR  R        
Sbjct: 240 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSY 299

Query: 288 --DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPER-FDPGPCVLGQERFTSGRHYW 344
             DVTL+P TAN  L+L+++RR V+    + + P   E+ +D    VLG + F+SG+HYW
Sbjct: 300 WVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS--VLGSQHFSSGKHYW 357

Query: 345 EVEVGDRTSWALGVCRENV-----------NRKEKGELSAGNGFWILVF-----LGSYYN 388
           EV+V  +T+W LGVC  ++           N          +G+W++         +Y +
Sbjct: 358 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 417

Query: 389 SSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFSPLSS 447
           SS   L  +  PPRRVG+FLDYEAG +SFY+ T+ G  ++ F +  F  TL P F+P  +
Sbjct: 418 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP-CN 476

Query: 448 SPTPMTICRP 457
              PMT+ RP
Sbjct: 477 CVIPMTLRRP 486


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  287 bits (734), Expect = 2e-77
 Identities = 177/490 (36%), Positives = 266/490 (54%), Gaps = 37/490 (7%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56
           M +P L  +++EE TC ICL+  T+P+  DCGH+FC+ CI    R      EG  +CP C
Sbjct: 29  MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 87

Query: 57  RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114
           +      NLRPNR LA +    R   L P   +   +C  H E L  FC ++ +++C  C
Sbjct: 88  QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 147

Query: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174
           ERS EH  H    +++ A++ + K ++SL+ L+ + Q+A    A   E    W+  +E +
Sbjct: 148 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 207

Query: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234
           R  +  EF +LR +L   EQ+ L++LE+EE + L  + E    L  Q+  L ELI++LE 
Sbjct: 208 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 267

Query: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG------- 287
           RCQ   + LLQD+ D   R +   L+ PE +P +LR++ R P L   LR  R        
Sbjct: 268 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSY 327

Query: 288 --DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPER-FDPGPCVLGQERFTSGRHYW 344
             DVTL+P TAN  L+L+++RR V+    + + P   E+ +D    VLG + F+SG+HYW
Sbjct: 328 WVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS--VLGSQHFSSGKHYW 385

Query: 345 EVEVGDRTSWALGVCRENV-----------NRKEKGELSAGNGFWILVF-----LGSYYN 388
           EV+V  +T+W LGVC  ++           N          +G+W++         +Y +
Sbjct: 386 EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYED 445

Query: 389 SSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFSPLSS 447
           SS   L  +  PPRRVG+FLDYEAG +SFY+ T+ G  ++ F +  F  TL P F+P  +
Sbjct: 446 SSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP-CN 504

Query: 448 SPTPMTICRP 457
              PMT+ RP
Sbjct: 505 CVIPMTLRRP 514


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  278 bits (712), Expect = 6e-75
 Identities = 160/467 (34%), Positives = 247/467 (52%), Gaps = 17/467 (3%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           MA     T LQ EA C+ICLDY +DPV  +CGHNFCR CI++ W   +  + CP CR   
Sbjct: 1   MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQC 60

Query: 61  PQRNLRPNRPLAKMAEMARRLHPPSPVPQG-----VCPAHREPLAAFCGDELRLLCAACE 115
            + + R N  L +M E+A+ L       +      +C  H +PL+ FC ++L +LC  C 
Sbjct: 61  QEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCT 120

Query: 116 RSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQR 175
           +  +H  H VRP++ AA   + +    ++ L+KQ+ D     +   +  +  ++MVE+QR
Sbjct: 121 QPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQR 180

Query: 176 QNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGR 235
           Q +  EFE L + L  E+Q +L RL EEE +   +L          SA L   ++++   
Sbjct: 181 QELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVEL 240

Query: 236 CQLPALGLLQDIKDALRRVQDVKLQPPEVVPMEL-RTVCRVP----GLVETLRRFRGDVT 290
            +L  L LL  IK       +     P +  + L R  C  P     L   +++F+ ++ 
Sbjct: 241 SELSELELLSQIKIFYESENE---SSPSIFSIHLKRDGCSFPPQYSALQRIIKKFKVEII 297

Query: 291 LDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGD 350
           LDP+TA+P LI+SED++ V+    +Q +P  P+RF   P VLG   F SGRH+WE+EVGD
Sbjct: 298 LDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGD 357

Query: 351 RTSWALGVCRENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAP--LRDPPRRVGIFL 408
           ++ WA+G+C++++  K +   SA    W +      Y++      P  L    R +GIFL
Sbjct: 358 KSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFPTPLLLEVKARAIGIFL 417

Query: 409 DYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTIC 455
           DYE G +SFY+  + S +  F +  F+G LRP F  +     P+ IC
Sbjct: 418 DYEMGEISFYNMAEKSHICTFTD-TFTGPLRPYFY-VGPDSQPLRIC 462


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  275 bits (704), Expect = 5e-74
 Identities = 162/463 (34%), Positives = 246/463 (53%), Gaps = 23/463 (4%)

Query: 9   NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
           NLQEE++C ICL+Y  DPV  +CGHNFCR C+   W   +  + CP CR   P ++ R N
Sbjct: 9   NLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRN 68

Query: 69  RPLAKMAEMARRLH-----PPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAH 123
             L  + E+A++L              +C  H + L  FC  +L +LC  C  S +H  H
Sbjct: 69  PQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKH 128

Query: 124 RVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFE 183
            + P++ AA   +  LE SLE LR  ++             V  +K VE +R+ +  EFE
Sbjct: 129 YICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFE 188

Query: 184 RLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGL 243
           ++R  L  E++ +L+++++EE+ +L +L E    L    + L  L+ E+EG+     L L
Sbjct: 189 QIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNLEL 248

Query: 244 LQDIKDALRRVQDVKLQPPEVVPMELRTVC-----RVPGLVETLRRFRGDVTLDPDTANP 298
           L   K    + Q++K   PE+    L         +  GL   ++ F+ DV LD +TA+P
Sbjct: 249 LTQAKSMHHKYQNLKC--PELFSFRLTKYGFSLPPQYSGLDRIIKPFQVDVILDLNTAHP 306

Query: 299 ELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGV 358
           +L++SEDR++V+    ++ +   P RF   P VLG +RF+SGRHYWEVEVG++  W LGV
Sbjct: 307 QLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGV 366

Query: 359 CRENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPLRD------PPRRVGIFLDYEA 412
           C++ + R  + + S   GFW    +G Y  S   A  P          P ++GIFLDYE 
Sbjct: 367 CQDCLLRNWQDQPSVLGGFWA---IGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYEL 423

Query: 413 GHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTIC 455
           G LSFY+  D S+L+ F +  F+  + P F   + S  P+ IC
Sbjct: 424 GDLSFYNMNDRSILYTFNDC-FTEAVWPYFYTGTDS-EPLKIC 464


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  268 bits (684), Expect = 1e-71
 Identities = 166/457 (36%), Positives = 235/457 (51%), Gaps = 52/457 (11%)

Query: 47  PEGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSP-----VPQGVCPAHREPLAA 101
           P   + CP+CR+  P+R+ RPN  LA M ++ R++HP          QG+CP H+E L  
Sbjct: 177 PRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKL 236

Query: 102 FCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQAD 161
           FC  +   +C  C  S  H  H V PL++  ++ KAKL+  +E LRK ++     +A+ +
Sbjct: 237 FCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEE 296

Query: 162 ETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQ 221
                 +  ++S+   V  EF RL R LAEE+  L +RL E     L R    A+ L +Q
Sbjct: 297 RRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQ 356

Query: 222 SAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCR------- 274
           +A L+ L+AE + R Q   L LLQDIK+   R ++V+LQPPEV   +    C+       
Sbjct: 357 AAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD---PCQPHSHDFL 413

Query: 275 VPGLVETLRRF-----RGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGP 329
              +V  + R      R D+TLDPDTA+P L+LS DRR V+  + RQ + D P+RF    
Sbjct: 414 TDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADC 473

Query: 330 CVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEK---GELSAGNG---------- 376
           CVLG + F SGRHYWEVEVG R  WA+G  RE+ + KEK   G  S G+G          
Sbjct: 474 CVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHR 533

Query: 377 ---------------FWILVFLGSYY---NSSERALAPLRDPPRRVGIFLDYEAGHLSFY 418
                           W +   G  Y   +S+E+ L    + PRR G++LDYEAG L FY
Sbjct: 534 RRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFY 593

Query: 419 SATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTIC 455
           +A   + +  F        + P F  LS   T + +C
Sbjct: 594 NAETLAHVHTFSAAFLGERVFPFFRVLSKG-TRIKLC 629



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 28/42 (66%), Positives = 31/42 (73%)

Query: 4  PDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWG 45
          P+    LQEEA CAICLDYFTDPV   CGHNFCR C+ + WG
Sbjct: 8  PNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  265 bits (677), Expect = 7e-71
 Identities = 170/494 (34%), Positives = 262/494 (53%), Gaps = 48/494 (9%)

Query: 3   APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPECRE 58
           A  +  N+QEE TC ICL+  T+P+  DCGH+ CR CI    +       G  +CP C  
Sbjct: 2   ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGI 61

Query: 59  LSPQRNLRPNRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACER 116
                +L+ N+ LA + E  +  +L P +   + +C  H E L  FC ++ +++C  CER
Sbjct: 62  SYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 121

Query: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176
           S EH  H     ++  ++ + KL+  L+ L+K+ ++A   +A   E    W+  V+++RQ
Sbjct: 122 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 181

Query: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236
            +  EF++LR +L  EEQ+ LQRLEEEE + L +  E    L QQ   + ELI+++E R 
Sbjct: 182 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 241

Query: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG--------- 287
           Q   + LLQD+   ++  +  +L+ P++V  +L+TV   P L   L+ FR          
Sbjct: 242 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 301

Query: 288 DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSP-ERFDPGPCVLGQERFTSGRHYWEV 346
           DVTL+    N  L+LSED+R V       ++P  P + ++ G  VLG + F+SG+HYWEV
Sbjct: 302 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG--VLGSQYFSSGKHYWEV 353

Query: 347 EVGDRTSWALGV-CRENVNRKEKGELSAGN------------GFWIL---------VFLG 384
           +V  +T+W LGV CR      +       N            G+W++         VF  
Sbjct: 354 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 413

Query: 385 SYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFS 443
           S  +  E     +  PP RVG+FLDYEAG +SF++ T  GSL++ F +  FS  + P F+
Sbjct: 414 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFN 473

Query: 444 PLSSSPTPMTICRP 457
           P  + P PMT+C P
Sbjct: 474 PW-NCPAPMTLCPP 486


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  265 bits (677), Expect = 7e-71
 Identities = 170/494 (34%), Positives = 262/494 (53%), Gaps = 48/494 (9%)

Query: 3   APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPECRE 58
           A  +  N+QEE TC ICL+  T+P+  DCGH+ CR CI    +       G  +CP C  
Sbjct: 2   ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGI 61

Query: 59  LSPQRNLRPNRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACER 116
                +L+ N+ LA + E  +  +L P +   + +C  H E L  FC ++ +++C  CER
Sbjct: 62  SYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 121

Query: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176
           S EH  H     ++  ++ + KL+  L+ L+K+ ++A   +A   E    W+  V+++RQ
Sbjct: 122 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 181

Query: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236
            +  EF++LR +L  EEQ+ LQRLEEEE + L +  E    L QQ   + ELI+++E R 
Sbjct: 182 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 241

Query: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG--------- 287
           Q   + LLQD+   ++  +  +L+ P++V  +L+TV   P L   L+ FR          
Sbjct: 242 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 301

Query: 288 DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSP-ERFDPGPCVLGQERFTSGRHYWEV 346
           DVTL+    N  L+LSED+R V       ++P  P + ++ G  VLG + F+SG+HYWEV
Sbjct: 302 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG--VLGSQYFSSGKHYWEV 353

Query: 347 EVGDRTSWALGV-CRENVNRKEKGELSAGN------------GFWIL---------VFLG 384
           +V  +T+W LGV CR      +       N            G+W++         VF  
Sbjct: 354 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 413

Query: 385 SYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFS 443
           S  +  E     +  PP RVG+FLDYEAG +SF++ T  GSL++ F +  FS  + P F+
Sbjct: 414 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFN 473

Query: 444 PLSSSPTPMTICRP 457
           P  + P PMT+C P
Sbjct: 474 PW-NCPAPMTLCPP 486


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  265 bits (677), Expect = 7e-71
 Identities = 170/494 (34%), Positives = 262/494 (53%), Gaps = 48/494 (9%)

Query: 3   APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPECRE 58
           A  +  N+QEE TC ICL+  T+P+  DCGH+ CR CI    +       G  +CP C  
Sbjct: 356 ASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGI 415

Query: 59  LSPQRNLRPNRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACER 116
                +L+ N+ LA + E  +  +L P +   + +C  H E L  FC ++ +++C  CER
Sbjct: 416 SYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCER 475

Query: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176
           S EH  H     ++  ++ + KL+  L+ L+K+ ++A   +A   E    W+  V+++RQ
Sbjct: 476 SQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQ 535

Query: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236
            +  EF++LR +L  EEQ+ LQRLEEEE + L +  E    L QQ   + ELI+++E R 
Sbjct: 536 RIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRS 595

Query: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRG--------- 287
           Q   + LLQD+   ++  +  +L+ P++V  +L+TV   P L   L+ FR          
Sbjct: 596 QWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV 655

Query: 288 DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSP-ERFDPGPCVLGQERFTSGRHYWEV 346
           DVTL+    N  L+LSED+R V       ++P  P + ++ G  VLG + F+SG+HYWEV
Sbjct: 656 DVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG--VLGSQYFSSGKHYWEV 707

Query: 347 EVGDRTSWALGV-CRENVNRKEKGELSAGN------------GFWIL---------VFLG 384
           +V  +T+W LGV CR      +       N            G+W++         VF  
Sbjct: 708 DVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEE 767

Query: 385 SYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFS 443
           S  +  E     +  PP RVG+FLDYEAG +SF++ T  GSL++ F +  FS  + P F+
Sbjct: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFN 827

Query: 444 PLSSSPTPMTICRP 457
           P  + P PMT+C P
Sbjct: 828 PW-NCPAPMTLCPP 840



 Score =  183 bits (465), Expect = 3e-46
 Identities = 105/289 (36%), Positives = 159/289 (55%), Gaps = 7/289 (2%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI----RRCWGQPEGPYACPEC 56
           M +P L  +++EE TC ICL+  T+P+  DCGH+FC+ CI    R      EG  +CP C
Sbjct: 29  MTSPVL-VDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVC 87

Query: 57  RELSPQRNLRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114
           +      NLRPNR LA +    R   L P   +   +C  H E L  FC ++ +++C  C
Sbjct: 88  QTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLC 147

Query: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQ 174
           ERS EH  H    +++ A++ + K ++SL+ L+ + Q+A    A   E    W+  +E +
Sbjct: 148 ERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE 207

Query: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234
           R  +  EF +LR +L   EQ+ L++LE+EE + L  + E    L  Q+  L ELI++LE 
Sbjct: 208 RCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLER 267

Query: 235 RCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLR 283
           RCQ   + LLQD+ D   R +   L+ PE +P +LR++ R P L   LR
Sbjct: 268 RCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLR 316


>gi|198442878 tripartite motif-containing 17 isoform 3 [Homo
           sapiens]
          Length = 343

 Score =  264 bits (674), Expect = 1e-70
 Identities = 143/308 (46%), Positives = 188/308 (61%), Gaps = 12/308 (3%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP---------EGPY 51
           M A +L+  LQEEATC+ICLDYFTDPVMT CGHNFCR CI+  W +          +G +
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 52  ACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLC 111
            CPECRE+SPQRNL PNR L K+AEMA++   P    Q +C  H EPL  FC  +   +C
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQ--HPGLQKQDLCQEHHEPLKLFCQKDQSPIC 118

Query: 112 AACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMV 171
             C  S EH  HRV P ++A +  K KLE+ +E+LR+Q+      QA+ +++   WQ  V
Sbjct: 119 VVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKV 178

Query: 172 ESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAE 231
           + +R+ ++ EFE++   L EEEQ+LLQ LE EE E   RLRE  A L +Q   L  L+ +
Sbjct: 179 KERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQ 238

Query: 232 LEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVV-PMELRTVCRVPGLVETLRRFRGDVT 290
           LE R     L +LQD+K+ L R  +V +Q PEV  P   RTVCRVPG +E LR F G   
Sbjct: 239 LEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLGKWA 298

Query: 291 LDPDTANP 298
               T++P
Sbjct: 299 PRARTSDP 306


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  262 bits (670), Expect = 4e-70
 Identities = 169/497 (34%), Positives = 257/497 (51%), Gaps = 49/497 (9%)

Query: 3   APDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP---EGPYACPECREL 59
           A  +  N++EE TC ICL+  T P+  DCGH+FC+ C+     +    +G  +CP CR  
Sbjct: 2   ASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRIS 61

Query: 60  SPQRNLRPNRPLAKMAEMARRLHPPSPVPQGV--CPAHREPLAAFCGDELRLLCAACERS 117
               N+RPNR +A + E  R +   SP  Q V  C  H E L  FC ++ +++C  CERS
Sbjct: 62  YQPENIRPNRHVANLVEKLREVKL-SPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS 120

Query: 118 GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQN 177
            EH  H   P ++ A++ + KL+ +LE LR++ Q+A   +A   E    W+  ++  + N
Sbjct: 121 QEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN 180

Query: 178 VLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQ 237
           VL +FE+LR +L  EE   LQ LE+EE ++L  L      + QQ+  L ELI++LE R Q
Sbjct: 181 VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ 240

Query: 238 LPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVP---GLVET------LRRFRGD 288
              + LLQ +   ++R ++V L+ PE  P   R V R P   G++E       +RR+  D
Sbjct: 241 GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD 300

Query: 289 VTLDPDTANPELILSEDRRSVQ----------RGDLRQALPDSPERFDPGPCVLGQERFT 338
           VT+ P+  +   ++SED+R V           RG   Q   +    F+    +LG +  T
Sbjct: 301 VTVAPNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVN----FNYCTGILGSQSIT 355

Query: 339 SGRHYWEVEVGDRTSWALGVCR-----ENVNRKEKGELSAGNGFWILVFL---------- 383
           SG+HYWEV+V  +T+W LGVC         N ++        G+W++             
Sbjct: 356 SGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQD 415

Query: 384 GSYYNSSERALAPLR--DPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRP 440
            S++  S   + PL     P RVG+FLDYEA  +SF++ T+ G L++ F    FS  + P
Sbjct: 416 SSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFP 475

Query: 441 LFSPLSSSPTPMTICRP 457
             +P      PMT+C P
Sbjct: 476 YLNPRKCG-VPMTLCSP 491


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score =  257 bits (656), Expect = 2e-68
 Identities = 152/447 (34%), Positives = 232/447 (51%), Gaps = 8/447 (1%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           M + DL    Q E  C IC++YF DPV  DCGH+FCR C+  C  +   P  CP CR+ S
Sbjct: 1   MDSDDLQV-FQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTS 59

Query: 61  PQRNLRPNRPLAKMAEMARRLHPPS-PVPQGVCPAHREPLAAFCGDELRLLCAACERSGE 119
            + N   N  L K++ +AR+  P +      +C  H E    FC  + RLLC  C  S E
Sbjct: 60  EKPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPE 119

Query: 120 HWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVL 179
           H AH   P+  AAE+ + KL K +++L +  Q+      Q   T    +  V  +++ + 
Sbjct: 120 HMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRIIT 179

Query: 180 GEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLP 239
            +++++   L EEEQ+ LQ LE E  E+  +L++    + Q    + ++  EL   C +P
Sbjct: 180 IQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMP 239

Query: 240 ALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPE 299
            + LLQD+++   R    ++Q P+ V  EL + C + G+++ L  FR D  L  +     
Sbjct: 240 DVVLLQDVRNVSARTDLAQMQKPQPVNPELTSWC-ITGVLDMLNNFRVDSALSTEMIPCY 298

Query: 300 LILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVC 359
           + LSED R V  GD   + P  P+  D    V G + FTSG+HYWEV+V   ++W LGVC
Sbjct: 299 ISLSEDVRYVIFGDDHLSAPTDPQGVD-SFAVWGAQAFTSGKHYWEVDVTLSSNWILGVC 357

Query: 360 RENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPL----RDPPRRVGIFLDYEAGHL 415
           R++        + +   F+++    S + S      PL    + P  RVG+FLDY+ G +
Sbjct: 358 RDSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSV 417

Query: 416 SFYSATDGSLLFIFPEIPFSGTLRPLF 442
           SF+  + GSL++ FP   FS  LRP F
Sbjct: 418 SFFDVSKGSLIYGFPPSSFSSPLRPFF 444


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score =  254 bits (650), Expect = 9e-68
 Identities = 150/447 (33%), Positives = 233/447 (52%), Gaps = 8/447 (1%)

Query: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60
           M + DL    Q E  C IC++YF DPV  DCGH+FCR C+  C  +   P  CP CR++S
Sbjct: 1   MDSDDLQV-FQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKIS 59

Query: 61  PQRNLRPNRPLAKMAEMARRLHPPS-PVPQGVCPAHREPLAAFCGDELRLLCAACERSGE 119
            + N   N  L K++ +AR+  P +      +C  H E    FC  + RLLC  C  S E
Sbjct: 60  EKPNFNTNVVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPE 119

Query: 120 HWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVL 179
           H AH   P+  AAE+ + KL K +++L +  Q+      Q   T    +  V  +++ + 
Sbjct: 120 HMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKRIIT 179

Query: 180 GEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLP 239
            +++++   L EEEQ+ LQ LE E  E+  +L++    + Q    + ++  EL   C +P
Sbjct: 180 IQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVP 239

Query: 240 ALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPE 299
            + LLQD+++   R    ++Q P+ V  EL + C + G+++ L  FR D  L  +     
Sbjct: 240 DVELLQDVRNVSARTDLAQMQKPQPVNPELTSWC-ITGVLDMLNNFRVDSALSTEMIPCY 298

Query: 300 LILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVC 359
           + LSED R V  GD   + P  P+  D    V G + FTSG+HYWEV+V   ++W LGVC
Sbjct: 299 ISLSEDVRYVIFGDDHLSAPTDPQGVD-SFAVWGAQAFTSGKHYWEVDVTLSSNWILGVC 357

Query: 360 RENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPL----RDPPRRVGIFLDYEAGHL 415
           +++        + +   F+++    S + S      PL    + P  +VG+FLDY+ G +
Sbjct: 358 QDSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSV 417

Query: 416 SFYSATDGSLLFIFPEIPFSGTLRPLF 442
           SF+  + GSL++ FP   FS  LRP F
Sbjct: 418 SFFDVSKGSLIYGFPPSSFSSPLRPFF 444


>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
          Length = 446

 Score =  251 bits (640), Expect = 1e-66
 Identities = 153/446 (34%), Positives = 236/446 (52%), Gaps = 16/446 (3%)

Query: 5   DLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRN 64
           D S   Q+E TC ICL+Y  DPV   CGH+FCR C+   W + + P  CP CRE SP+ +
Sbjct: 4   DFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMD 63

Query: 65  LRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWA 122
            + N  L  +  +AR+  L       + +C  HR+    FC  +  LLC  C  S EH A
Sbjct: 64  FKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGA 123

Query: 123 HRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEF 182
           H+  P+++AAE+ + KL K +  L K++Q+      +   T  LW+  V  + Q +  E+
Sbjct: 124 HKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIRNEY 183

Query: 183 ERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALG 242
            +L  +L +EE+Q L+RL +E  E+  +L+     + Q+S HL E+  EL   C  P + 
Sbjct: 184 RKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVE 243

Query: 243 LLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELIL 302
           LLQD+ D + R + V L  P+ V  EL T   + GLV  L RFR +++   +  N  + L
Sbjct: 244 LLQDLGDIVARSESVLLHMPQPVNPEL-TAGPITGLVYRLNRFRVEISFHFEVTNHNIRL 302

Query: 303 SEDRRS--VQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCR 360
            ED RS   +RG L     D  + F       G   F+ G+HYWE++V +   WALGVC 
Sbjct: 303 FEDVRSWMFRRGPLNS---DRSDYF----AAWGARVFSFGKHYWELDVDNSCDWALGVCN 355

Query: 361 ENVNRKEKGELSAGNGFWILVF-LGSYYN---SSERALAPLRDPPRRVGIFLDYEAGHLS 416
            +  RK    +++ + F +L   + +++N   +S      +  P  RVG+FLD+E+G +S
Sbjct: 356 NSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVS 415

Query: 417 FYSATDGSLLFIFPEIPFSGTLRPLF 442
           F + T  SL++ +P    +  +RP F
Sbjct: 416 FLNVTKSSLIWSYPAGSLTFPVRPFF 441


>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
           protein 1 [Homo sapiens]
          Length = 446

 Score =  244 bits (623), Expect = 1e-64
 Identities = 152/446 (34%), Positives = 235/446 (52%), Gaps = 16/446 (3%)

Query: 5   DLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRN 64
           D S   Q+E TC ICL+Y  DPV   CGH+FCR C+   W + + P  CP CRE SP+ +
Sbjct: 4   DFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMD 63

Query: 65  LRPNRPLAKMAEMARR--LHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWA 122
            + N  L  +  +AR+  L       + +C  HR+    FC  +  LLC  C  S EH A
Sbjct: 64  FKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGA 123

Query: 123 HRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEF 182
           H+  P+++AAE+ + KL K +  L K++Q+      +   T  L +  V  + Q +  E+
Sbjct: 124 HKHYPIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQMIRNEY 183

Query: 183 ERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALG 242
            +L  +L +EE+Q L+RL +E  E+  +L+     + Q+S HL E+  EL   C  P + 
Sbjct: 184 RKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVE 243

Query: 243 LLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELIL 302
           LLQD+ D + R + V L  P+ V  EL T   + GLV  L RFR +++   +  N  + L
Sbjct: 244 LLQDLGDIVARSESVLLHMPQPVNPEL-TAGPITGLVYRLNRFRVEISFHFEVTNHNIRL 302

Query: 303 SEDRRS--VQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCR 360
            ED RS   +RG L     D  + F       G   F+ G+HYWE++V +   WALGVC 
Sbjct: 303 FEDVRSWMFRRGPLNS---DRSDYF----AAWGARVFSFGKHYWELDVDNSCDWALGVCN 355

Query: 361 ENVNRKEKGELSAGNGFWILVF-LGSYYN---SSERALAPLRDPPRRVGIFLDYEAGHLS 416
            +  RK    +++ + F +L   + +++N   +S      +  P  RVG+FLD+E+G +S
Sbjct: 356 NSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVS 415

Query: 417 FYSATDGSLLFIFPEIPFSGTLRPLF 442
           F + T  SL++ +P    +  +RP F
Sbjct: 416 FLNVTKSSLIWSYPAGSLTFPVRPFF 441


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  243 bits (619), Expect = 4e-64
 Identities = 147/438 (33%), Positives = 226/438 (51%), Gaps = 11/438 (2%)

Query: 11  QEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNRP 70
           Q E  C IC++YF DPV TDC H+FCR C+  C  +   P  CP CR++S + N   N  
Sbjct: 10  QNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKPNFNTNVA 69

Query: 71  LAKMAEMARRLHPPS-PVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQ 129
           L K+A +AR+  P +      +C  H E    FC  + RLLC  C  S EH AH   P+ 
Sbjct: 70  LKKLASLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIG 129

Query: 130 DAAEDLKA-KLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRL 188
            AAE+ +  KL K +++L K  Q+    Q   ++    +  +VE +R  ++  ++++   
Sbjct: 130 WAAEECRVQKLIKEMDYLWKINQET---QNNLNQETSKFCSLVEDKRNRIVYRYQKMHIF 186

Query: 189 LAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIK 248
           L EEEQ+ LQ LE E  E+  +L++    + Q    + ++  EL     +P + LLQD+ 
Sbjct: 187 LDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVG 246

Query: 249 DALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSEDRRS 308
           +   R    ++  P+ V  EL + C + G+++ L  FR D  L  +     + LSED R 
Sbjct: 247 NISARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRR 305

Query: 309 VQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEK 368
           V  GD  ++ P  P+  +    V   + FTSG+HYWEV+V   ++W LGVCR++      
Sbjct: 306 VIFGDDHRSAPMDPQGVE-SFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTN 364

Query: 369 GELSAGNGFWILVFLGSYYNSSERALAPL----RDPPRRVGIFLDYEAGHLSFYSATDGS 424
             + +   F+ +    S + S      PL    + P   VG+FLDY+ G +SF+  + GS
Sbjct: 365 IVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGS 424

Query: 425 LLFIFPEIPFSGTLRPLF 442
           L++ FP   FS  LRP F
Sbjct: 425 LIYGFPPSSFSSPLRPFF 442


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,393,911
Number of Sequences: 37866
Number of extensions: 1123083
Number of successful extensions: 6670
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 262
Number of HSP's successfully gapped in prelim test: 360
Number of HSP's that attempted gapping in prelim test: 5162
Number of HSP's gapped (non-prelim): 1274
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.