Guide to the Human Genome
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Search of human proteins with 21493039

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
         (845 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]       1683   0.0  
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]       1683   0.0  
gi|21493041 A-kinase anchor protein 3 [Homo sapiens]                  362   e-100
gi|217416354 sphingosine kinase type 1-interacting protein isofo...    57   7e-08
gi|217416352 sphingosine kinase type 1-interacting protein isofo...    56   1e-07
gi|7706457 A-kinase anchor protein 11 [Homo sapiens]                   52   3e-06
gi|89213250 intermediate filament family orphan isoform 4 [Homo ...    35   0.22 
gi|11968023 zinc finger protein 106 homolog [Homo sapiens]             35   0.22 
gi|4758650 kinesin family member 5C [Homo sapiens]                     34   0.50 
gi|56676335 RAP1 interacting factor 1 [Homo sapiens]                   34   0.65 
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    33   1.1  
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]     33   1.4  
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]      33   1.4  
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       32   1.9  
gi|111548668 zinc finger protein 676 [Homo sapiens]                    32   2.5  
gi|110349721 titin isoform novex-3 [Homo sapiens]                      32   3.2  
gi|110349719 titin isoform N2-A [Homo sapiens]                         32   3.2  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      32   3.2  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      32   3.2  
gi|110349715 titin isoform N2-B [Homo sapiens]                         32   3.2  
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]            32   3.2  
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    31   4.2  
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...    31   4.2  
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    31   4.2  
gi|209862748 ataxin 3-like [Homo sapiens]                              31   4.2  
gi|31982909 zinc finger protein 394 [Homo sapiens]                     31   4.2  
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...    31   4.2  
gi|121582460 hypothetical protein LOC79762 [Homo sapiens]              31   4.2  
gi|4502443 dystonin isoform 1e precursor [Homo sapiens]                31   5.5  
gi|157909822 pragmin [Homo sapiens]                                    31   5.5  

>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
          Length = 845

 Score = 1683 bits (4358), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60
           MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL
Sbjct: 1   MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60

Query: 61  NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120
           NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL
Sbjct: 61  NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120

Query: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180
           SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ
Sbjct: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180

Query: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240
           SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH
Sbjct: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240

Query: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300
           SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK
Sbjct: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300

Query: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360
           SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR
Sbjct: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360

Query: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420
           VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR
Sbjct: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420

Query: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480
           LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS
Sbjct: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480

Query: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540
           LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL
Sbjct: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540

Query: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600
           KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP
Sbjct: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600

Query: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660
           STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR
Sbjct: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660

Query: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720
           SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA
Sbjct: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720

Query: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780
           SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP
Sbjct: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780

Query: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840
           MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW
Sbjct: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840

Query: 841 LLANL 845
           LLANL
Sbjct: 841 LLANL 845


>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
          Length = 854

 Score = 1683 bits (4358), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60
           MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL
Sbjct: 10  MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 69

Query: 61  NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120
           NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL
Sbjct: 70  NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 129

Query: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180
           SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ
Sbjct: 130 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 189

Query: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240
           SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH
Sbjct: 190 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 249

Query: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300
           SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK
Sbjct: 250 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 309

Query: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360
           SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR
Sbjct: 310 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 369

Query: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420
           VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR
Sbjct: 370 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 429

Query: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480
           LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS
Sbjct: 430 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 489

Query: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540
           LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL
Sbjct: 490 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 549

Query: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600
           KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP
Sbjct: 550 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 609

Query: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660
           STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR
Sbjct: 610 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 669

Query: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720
           SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA
Sbjct: 670 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 729

Query: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780
           SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP
Sbjct: 730 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 789

Query: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840
           MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW
Sbjct: 790 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 849

Query: 841 LLANL 845
           LLANL
Sbjct: 850 LLANL 854


>gi|21493041 A-kinase anchor protein 3 [Homo sapiens]
          Length = 853

 Score =  362 bits (930), Expect = e-100
 Identities = 300/876 (34%), Positives = 432/876 (49%), Gaps = 184/876 (21%)

Query: 96  SDPVSVLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVN 155
           +DPV VL+WL  DL+K    FQ        +   +  ++ G+ H+  S + Y+       
Sbjct: 36  TDPVRVLSWLRRDLEKSTAEFQDVRFKPGESFGGETSNS-GDPHKGFSVDYYNTTTK--- 91

Query: 156 IDYLMNRPQNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRL 215
                  P+ L  EMT  +           P + P  Q    S     S+D++SFY NRL
Sbjct: 92  -----GTPERLHFEMTHKEI----------PCQGPRAQLGNGS-----SVDEVSFYANRL 131

Query: 216 SSLVIQMAHKEIKEKLEG-KSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVEL-- 272
           ++LVI MA KEI EK++G ++KC++ S+    GN+   +P    SKIASE+  E V    
Sbjct: 132 TNLVIAMARKEINEKIDGSENKCVYQSLYM--GNEP--TPTKSLSKIASELVNETVSACS 187

Query: 273 -TAAEMRGTGEESREGG--------------------------------QKSFLYSELSN 299
             AA  +  G   R  G                                +KSF Y E+  
Sbjct: 188 RNAAPDKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQGPDDKPPSKKSFFYKEVF- 246

Query: 300 KSKSGD--------------KQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKV 345
           +S++GD              +   Q    +F  S+S+G+M YAN V SDMMVS+MKTLK+
Sbjct: 247 ESRNGDYAREGGRFFPRERKRFRGQERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKI 306

Query: 346 HSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQ 405
                 I A+++LK+VLL+H KE+VSDLIDS ++NLH++TG LMTD+ FVSAVKR +F+ 
Sbjct: 307 QVKDTTI-ATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSH 365

Query: 406 WKQNATDIMEAMLKRLVSALIGE-------EKETKSQSLSYASLKAGSHDPKCRNQSLEF 458
             Q ATDIM+AML++L + +  +       + + K++S S  S+K G  DPK RN +   
Sbjct: 366 GSQKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMK-GMGDPKNRNVNF-- 422

Query: 459 STMKAEMKERDKGKMKSDP-CKSLTSAEKVGEHILKEGLTIWNQKQGNSCK--------- 508
             MK+E K R+  KM S+P  +  T A+ +GEHI+KEGLT+W++ Q   CK         
Sbjct: 423 -AMKSETKLRE--KMYSEPKSEEETCAKTLGEHIIKEGLTLWHKTQQKECKSLGFQHAAF 479

Query: 509 ----VATKACSN-----------------KDEKGEKINASTDSLAKDLIVSALKLIQYHL 547
                  K  S+                   EK E     +DS A+DLIVSAL LIQYHL
Sbjct: 480 EAPNTQRKPASDISFEYPEDIGNLSLPPYPPEKPENFMYDSDSWAEDLIVSALLLIQYHL 539

Query: 548 TQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKEN 607
            Q  +       +  G+T                  A    V   ES     P    +E 
Sbjct: 540 AQGGRRDARSFVEAAGTT---------------NFPANEPPVAPDESCLKSAPIVGDQE- 583

Query: 608 QHLDSQKMDMSNIVLMLIQKLLNENPFK---------CEDPCEGENK-CSEPRASKAASM 657
               ++K D+ ++    I+ LL+E  FK          E P + + K C  P AS    +
Sbjct: 584 ---QAEKKDLRSVFFNFIRNLLSETIFKRDQSPEPKVPEQPVKEDRKLCERPLASSPPRL 640

Query: 658 SNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAEL-E 716
               D+         ++  +      +GQ ++ L+ SVMKLC+I+AK  +  A+LAEL +
Sbjct: 641 -YEDDETPGALSGLTKMAVSQIDGHMSGQMVEHLMNSVMKLCVIIAKSCD--ASLAELGD 697

Query: 717 EQAASANKPN------------FRGT-----------RCIHS---GAMPQNYQDSLGHEV 750
           +++  A++               +GT           + IH+   G   Q  +      V
Sbjct: 698 DKSGDASRLTSAFPDSLYECLPAKGTGSAEAVLQNAYQAIHNEMRGTSGQPPEGCAAPTV 757

Query: 751 IVNNQCSTNSLQ-KQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 809
           IV+N   T+++Q KQLQAVLQW+AAS+ NVP+LYF GD +G  EKL Q+SA A +KG SV
Sbjct: 758 IVSNHNLTDTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSV 817

Query: 810 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLANL 845
           G +LQ V+++ KERQ +EAVG V   QLLDWL+ NL
Sbjct: 818 GEVLQSVLRYEKERQLNEAVGNVTPLQLLDWLMVNL 853



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 18/32 (56%), Positives = 24/32 (75%)

Query: 1  MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKV 32
          MS+ +DWL+S  GVCKVD+Y+P   Q QD K+
Sbjct: 1  MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKM 32


>gi|217416354 sphingosine kinase type 1-interacting protein isoform 1
            [Homo sapiens]
          Length = 1700

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 64/290 (22%), Positives = 109/290 (37%), Gaps = 35/290 (12%)

Query: 559  EDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMS 618
            E C G    ++++S+  E+  G  + K  ++  +        S CQ  +  LD++ +  +
Sbjct: 1437 EACAGEPEPFLSKSSLLEEAEGHSNDK--NIPDVVRGGDTAVSACQIHSDSLDTRDVPEA 1494

Query: 619  NIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQ--ELDC 676
                            +  D        SE        ++N  D  ++     Q  E   
Sbjct: 1495 EA----------STEARAPDEAPNPPSSSEESTGSWTQLANEEDNPDDTSSFLQLSERSM 1544

Query: 677  TSGMKQANGQF----IDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRC 732
            ++G   A        +D   ES+    +I            + E   A A+ P   GT  
Sbjct: 1545 SNGNSSATSSLGIMDLDIYQESMPSSPMINELVEEKKILKGQSESTEAPASGPP-TGT-- 1601

Query: 733  IHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQL 792
                A PQ    SL   +++N          +L+A LQWIAAS+  +P +YF   ++ ++
Sbjct: 1602 ----ASPQR---SL---LVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQENRI 1651

Query: 793  EKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLL 842
            EK   V      K + VG +   V+++ K  +      K  R  L DWLL
Sbjct: 1652 EKFLDVVQLVHRKSWKVGDIFHAVVQYCKMHEEQ----KDGRLSLFDWLL 1697


>gi|217416352 sphingosine kinase type 1-interacting protein isoform 2
            [Homo sapiens]
          Length = 1671

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 68/284 (23%), Positives = 112/284 (39%), Gaps = 52/284 (18%)

Query: 559  EDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMS 618
            E C G    ++++S+  E+  G  + K  ++  +        S CQ  +  LD++ +  +
Sbjct: 1437 EACAGEPEPFLSKSSLLEEAEGHSNDK--NIPDVVRGGDTAVSACQIHSDSLDTRDVPEA 1494

Query: 619  NIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTS 678
                        E   +   P E  N    P +S   S  + +  A E+       D TS
Sbjct: 1495 ------------EASTEARAPDEAPN----PPSSSEESTGSWTQLANEE----DNPDDTS 1534

Query: 679  GMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAM 738
               Q + + + +LVE    L               + E   A A+ P   GT      A 
Sbjct: 1535 SFLQLSERSMSELVEEKKIL-------------KGQSESTEAPASGPP-TGT------AS 1574

Query: 739  PQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQV 798
            PQ    SL   +++N          +L+A LQWIAAS+  +P +YF   ++ ++EK   V
Sbjct: 1575 PQR---SL---LVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQENRIEKFLDV 1628

Query: 799  SAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLL 842
                  K + VG +   V+++ K  +      K  R  L DWLL
Sbjct: 1629 VQLVHRKSWKVGDIFHAVVQYCKMHEEQ----KDGRLSLFDWLL 1668


>gi|7706457 A-kinase anchor protein 11 [Homo sapiens]
          Length = 1901

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 5/95 (5%)

Query: 750  VIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 809
            +I N      ++  QL+ +LQW+ AS+  V  LYF    D   ++   +S +  EKG+ V
Sbjct: 1811 LITNIDMEPCTVDPQLRIILQWLIASEAEVAELYF---HDSANKEFMLLSKQLQEKGWKV 1867

Query: 810  GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLAN 844
            G LLQ V+++ +    ++A  +   K L DWLL N
Sbjct: 1868 GDLLQAVLQYYEVM--EKASSEERCKSLFDWLLEN 1900



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 9/85 (10%)

Query: 59  NLNLGSLEEKEIIVIKDTEKK--------DQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQ 110
           +L+  SL E EII +K+  K         +QS   G +C+ + +P+ P   ++++ S L 
Sbjct: 87  SLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLS 146

Query: 111 KYALGFQHALSPSTSTCKHKVGDTE 135
           KYA G ++ L       KH++  T+
Sbjct: 147 KYATGIRYTLDTFLHQ-KHQLETTD 170


>gi|89213250 intermediate filament family orphan isoform 4 [Homo
           sapiens]
          Length = 563

 Score = 35.4 bits (80), Expect = 0.22
 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 13/133 (9%)

Query: 407 KQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKA--E 464
           ++N  D+++   K+LV ++ G ++E K+      SL   S  P+  +   E ST  +  E
Sbjct: 346 QRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSE-SEGPRQPDGDEEESTALSINE 404

Query: 465 MKERDKGKMKS----DPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEK 520
             +R   +++     D C SLT  E       +E L +W    G +   A      +++ 
Sbjct: 405 EMQRMLNQLREYDFEDDCDSLTWEET------EETLLLWEDFSGYAMAAAEAQGEQQEDS 458

Query: 521 GEKINASTDSLAK 533
            EK+   T+SL K
Sbjct: 459 LEKVIKDTESLFK 471


>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
          Length = 1883

 Score = 35.4 bits (80), Expect = 0.22
 Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 20/123 (16%)

Query: 581  GQSAKA-LSVKQLESHRAPGPSTCQK-EN---QHLDSQKMDMSNIV-LMLIQKLLNEN-- 632
            GQS KA + +KQ  + RA    T ++ EN   Q   S ++   +I+ LM + K LN    
Sbjct: 901  GQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQER 960

Query: 633  ---PFKCEDPCE--GENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQF 687
               P + ++  E  GE  C    AS A ++S+ +D A +         CTSG +Q +GQ 
Sbjct: 961  SIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDS-------SCTSGAEQNDGQS 1013

Query: 688  IDK 690
            I K
Sbjct: 1014 IRK 1016


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score = 34.3 bits (77), Expect = 0.50
 Identities = 72/386 (18%), Positives = 142/386 (36%), Gaps = 55/386 (14%)

Query: 400 RNLFNQWKQNATDIMEAMLKRL--VSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLE 457
           + L N  K+ AT+I+  +LK L  +  +IG         ++      G  + +     L 
Sbjct: 537 QELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVN------GVIEEEFTMARLY 590

Query: 458 FSTMKAEMKER-DKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSN 516
            S MK+E+K   ++ K                E  L     + +Q +    K  T    N
Sbjct: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEA-KIKSLTDYMQN 649

Query: 517 KDEKGEKINASTDSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYE 576
            ++K  ++  S DSL+++L     +   + ++ Q K K+                     
Sbjct: 650 MEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKE------------------HLT 691

Query: 577 KCGGGQSAKALSVKQLESHRAPGPSTCQK------ENQHLDSQKMDMSNIVLMLIQKLLN 630
           +    +  K    +Q+ESHR        +      E Q +  +  D++  + +  +KL +
Sbjct: 692 RLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSS 751

Query: 631 E-NPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFID 689
           + N  K ED         + R  K   +   +DK E+  ++ + L+ T   +      + 
Sbjct: 752 DYNKLKIED---------QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLR 802

Query: 690 KL-VESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGH 748
           KL V+ +        +  ND    +  ++Q  S  + N      +H   +  N       
Sbjct: 803 KLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDN------- 855

Query: 749 EVIVNNQCSTNSLQKQLQAVLQWIAA 774
               + +C    L+K+L+A  + + A
Sbjct: 856 ---ADLRCELPKLEKRLRATAERVKA 878


>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
          Length = 2472

 Score = 33.9 bits (76), Expect = 0.65
 Identities = 72/378 (19%), Positives = 151/378 (39%), Gaps = 42/378 (11%)

Query: 277  MRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYAN------- 329
            + GT   SR  G+     +E +   +S  K + + E ++  +   +G++V  N       
Sbjct: 1281 VNGTKRSSRRAGK-----AEQTGNKRS--KPLMRSEPEKNTEESVEGIVVLENNPPGLLN 1333

Query: 330  --QVASDMMVSLMKTLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGV 387
              +  SD  V L ++   H + K + A+ V   VLL  T  +    ++  +++  N   V
Sbjct: 1334 QTECVSDNQVHLSESTMEHDNTK-LKAATVENAVLLE-TNTVEEKNVEINLESKENTPPV 1391

Query: 388  LMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSH 447
            +++    V+   +    Q   N   +  +  +R  S ++  E  T+SQ       K  SH
Sbjct: 1392 VISADQMVNEDSQV---QITPNQKTLRRSSRRR--SEVV--ESTTESQD------KENSH 1438

Query: 448  DPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSC 507
              K R +  E    K+ +  +D       P + L + + + E+++++G  +  +  G + 
Sbjct: 1439 QKKERRKEEEKPLQKSPLHIKDDVL----PKQKLIAEQTLQENLIEKGSNLHEKTLGETS 1494

Query: 508  KVATKACSNKDEKGEKINASTDSLAKDLIVSALKLI----QYHLTQQTKGKDTCEEDCPG 563
              A    + K    E I +  D     +  S+ KL+    +Y   + ++G  +  E+   
Sbjct: 1495 ANAETEQNKKKADPENIKSEGDGTQDIVDKSSEKLVRGRTRYQTRRASQGLLSSIENSES 1554

Query: 564  STMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQK-ENQHLDSQKMDMSNIVL 622
             +     + ++ ++ G  ++    SV   +         C K ENQ  D +     ++ +
Sbjct: 1555 DSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSI 1614

Query: 623  M--LIQKLLNENPFKCED 638
               + +K    N   C+D
Sbjct: 1615 KSPICEKQDESNTVICQD 1632


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 3/86 (3%)

Query: 175  NTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGK 234
            N N+  +PS  P K  +  R  +  DG+  +      +++   L I+  HK  KE+++  
Sbjct: 1550 NGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQ-KDLEIEERHKRHKERMKQM 1608

Query: 235  SKCLHHSICPSPGNKERISPRTPASK 260
             K  H S    P  KE+  P     K
Sbjct: 1609 EKLRHRS--GDPKLKEKAKPADDGRK 1632


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 21/138 (15%)

Query: 400 RNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFS 459
           ++L N+ ++   D  +  +KRL +  + +  E+     S   +   S + K  N      
Sbjct: 346 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN------ 399

Query: 460 TMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDE 519
               E+K ++  K+  +  K   + EK GE  LK     W+Q Q +           K E
Sbjct: 400 ----ELKNKNTSKINGEEGKPHNN-EKAGEETLKNSQPPWDQIQED----------KKHE 444

Query: 520 KGEKINASTDSLAKDLIV 537
           + EK  +    L +D+I+
Sbjct: 445 EAEKRKSVDTQLQEDMII 462


>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 21/138 (15%)

Query: 400 RNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFS 459
           ++L N+ ++   D  +  +KRL +  + +  E+     S   +   S + K  N      
Sbjct: 127 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN------ 180

Query: 460 TMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDE 519
               E+K ++  K+  +  K   + EK GE  LK     W+Q Q +           K E
Sbjct: 181 ----ELKNKNTSKINGEEGKPHNN-EKAGEETLKNSQPPWDQIQED----------KKHE 225

Query: 520 KGEKINASTDSLAKDLIV 537
           + EK  +    L +D+I+
Sbjct: 226 EAEKRKSVDTQLQEDMII 243


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 7/77 (9%)

Query: 608 QHLDSQKMDMSNIVLMLIQKLLN---ENPFKCEDP----CEGENKCSEPRASKAASMSNR 660
           +H  + K D +  ++ L++++ N   +  + C+ P     +G      PR++ AA  ++ 
Sbjct: 668 RHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTATAPPPRSNHAAEEASS 727

Query: 661 SDKAEEQCQEHQELDCT 677
            D+ EE+ Q  Q  + T
Sbjct: 728 EDEEEEEVQAMQSFNST 744


>gi|111548668 zinc finger protein 676 [Homo sapiens]
          Length = 588

 Score = 32.0 bits (71), Expect = 2.5
 Identities = 43/203 (21%), Positives = 71/203 (34%), Gaps = 28/203 (13%)

Query: 483 SAEKVGEHILKEGLTIWNQKQGNSCKVAT--KACSNKDEKGEKINASTDSLAKDLIVSAL 540
           +  K G + L + LT    K     K A     CSN +    +         K+ + S  
Sbjct: 92  NVHKEGYNKLNQSLTTTQSKVFQCGKYANVFHKCSNSNRHKIRHTGEKGLKCKEYVRSFC 151

Query: 541 KLIQYHLTQQTK-----GKDTCEEDCPGSTMGYMAQSTQY------------EKCGGGQS 583
            L   HL+Q  +         CEE+  G    + +  T Y            E+CG   S
Sbjct: 152 MLS--HLSQHERIYTRENSYKCEEN--GKAFNWSSTLTYYKSIHTGEKPYKCEECGKAFS 207

Query: 584 AKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGE 643
             ++  K    H    P  C++  +  +   +   + ++        E P+KCE+  +G 
Sbjct: 208 KFSILTKHKVIHTGEKPYKCEECGKAFNRSSILTKHKIIHT-----GEKPYKCEECGKGF 262

Query: 644 NKCSEPRASKAASMSNRSDKAEE 666
           +  S     KA     +  K EE
Sbjct: 263 SSVSTLNTHKAIHAEEKPYKCEE 285


>gi|110349721 titin isoform novex-3 [Homo sapiens]
          Length = 5604

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 38   VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91
            VS  N+E K Y +     S G   + S   ++ + +KD  K+DQ +       + + C  
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349

Query: 92   KQAPSDPVSVLNWL 105
            K  P  P+++L  L
Sbjct: 2350 KMKPR-PIAILQGL 2362


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 38   VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91
            VS  N+E K Y +     S G   + S   ++ + +KD  K+DQ +       + + C  
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349

Query: 92   KQAPSDPVSVLNWL 105
            K  P  P+++L  L
Sbjct: 2350 KMKPR-PIAILQGL 2362


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 38   VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91
            VS  N+E K Y +     S G   + S   ++ + +KD  K+DQ +       + + C  
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303

Query: 92   KQAPSDPVSVLNWL 105
            K  P  P+++L  L
Sbjct: 2304 KMKPR-PIAILQGL 2316


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 38   VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91
            VS  N+E K Y +     S G   + S   ++ + +KD  K+DQ +       + + C  
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303

Query: 92   KQAPSDPVSVLNWL 105
            K  P  P+++L  L
Sbjct: 2304 KMKPR-PIAILQGL 2316


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 38   VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91
            VS  N+E K Y +     S G   + S   ++ + +KD  K+DQ +       + + C  
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303

Query: 92   KQAPSDPVSVLNWL 105
            K  P  P+++L  L
Sbjct: 2304 KMKPR-PIAILQGL 2316


>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
          Length = 1352

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 29/171 (16%)

Query: 171  TAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEK 230
            ++++ +  + SP+  PA+P        SP  + S+   S    + +S +   A     +K
Sbjct: 1079 SSSRGSGRHSSPA--PAQPKKES----SPKSQDSVSSPSPQKQKSASALTYTASSTSAKK 1132

Query: 231  LEG----------KSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGT 280
              G          KS+   HS+      +   S R  A+  +   +    +  A E RG 
Sbjct: 1133 ASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTSKPNSPRVSQARAGEGRGA 1192

Query: 281  GEESREGGQKSF------LYSELSNKSKSGDKQMS-------QRESKEFAD 318
            G+  R     S       + S L   SKS DK +S       Q+E++   D
Sbjct: 1193 GKHVRSSSMASLRSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKETRRSTD 1243


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
            sapiens]
          Length = 1198

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%)

Query: 23   EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 82
            EG++D+D            +  D +Y + + +     +  G   E  + +      + ++
Sbjct: 893  EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 941

Query: 83   KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 138
             +EGS+    Q P  P        SD   +    + A S    PS ST K ++G   G  
Sbjct: 942  HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 993

Query: 139  HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 190
            H  S   + +     AD V  D   +R +  +      KN        N+SP APPA   
Sbjct: 994  HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 1053

Query: 191  STQRAVISPDGE 202
                    P  E
Sbjct: 1054 DKMMKSFKPTSE 1065


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%)

Query: 23  EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 82
           EG++D+D            +  D +Y + + +     +  G   E  + +      + ++
Sbjct: 214 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 262

Query: 83  KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 138
            +EGS+    Q P  P        SD   +    + A S    PS ST K ++G   G  
Sbjct: 263 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 314

Query: 139 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 190
           H  S   + +     AD V  D   +R +  +      KN        N+SP APPA   
Sbjct: 315 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 374

Query: 191 STQRAVISPDGE 202
                   P  E
Sbjct: 375 DKMMKSFKPTSE 386


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%)

Query: 23  EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 82
           EG++D+D            +  D +Y + + +     +  G   E  + +      + ++
Sbjct: 612 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 660

Query: 83  KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 138
            +EGS+    Q P  P        SD   +    + A S    PS ST K ++G   G  
Sbjct: 661 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 712

Query: 139 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 190
           H  S   + +     AD V  D   +R +  +      KN        N+SP APPA   
Sbjct: 713 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 772

Query: 191 STQRAVISPDGE 202
                   P  E
Sbjct: 773 DKMMKSFKPTSE 784


>gi|209862748 ataxin 3-like [Homo sapiens]
          Length = 355

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 17/131 (12%)

Query: 220 IQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRT----PASKIASEMAYEAVELTAA 275
           ++++ +E   + E     +  S+  S GN  +  P+T    PAS+   ++  +  E    
Sbjct: 233 LELSRQETNREDEHLRSTIELSMQGSSGNTSQDLPKTSCVTPASEQPKKIKEDYFEKHQQ 292

Query: 276 EMRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDM 335
           E +   ++S   G  S+L+   +  S++ +  +S        D IS+G +    Q A D 
Sbjct: 293 EQKQQQQQSDLPGHSSYLHERPTTSSRAIESDLS--------DDISEGTV----QAAVDT 340

Query: 336 MVSLM-KTLKV 345
           ++ +M K LK+
Sbjct: 341 ILEIMRKNLKI 351


>gi|31982909 zinc finger protein 394 [Homo sapiens]
          Length = 561

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 42/190 (22%), Positives = 66/190 (34%), Gaps = 38/190 (20%)

Query: 576 EKCGGGQSAKALSVKQLESHRAPGPSTCQK------ENQHLDSQKMDMSNIVLMLIQKLL 629
           ++CG   S  A   K   +H    P TC K      +N HL+  +   S           
Sbjct: 389 QECGKSFSQSAALTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHS----------- 437

Query: 630 NENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEE--QCQEHQELDCTSGMKQANGQF 687
            +  FKCE+       C E           R  K E   +C+E     C    KQ +  F
Sbjct: 438 RDKHFKCEE-------CGETCHISNLFRHQRLHKGERPYKCEE-----CEKSFKQRSDLF 485

Query: 688 IDKLVESVMKL--CLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDS 745
               + +  K   C +  K  N  A L +  ++  +  KP     +C+  G   +     
Sbjct: 486 KHHRIHTGEKPYGCSVCGKRFNQSATLIK-HQRIHTGEKP----YKCLECGERFRQSTHL 540

Query: 746 LGHEVIVNNQ 755
           + H+ I  N+
Sbjct: 541 IRHQRIHQNK 550


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
           [Homo sapiens]
          Length = 1585

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 35/215 (16%)

Query: 154 VNIDYLMNRPQNLRLEMTAAKNTNNN-----QSPSAPPAKPPSTQRAVISPDGECSIDDL 208
           + ++ L N P+ ++LE   A  T +       +P  PPA PP T   V +     S    
Sbjct: 385 LELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSA 444

Query: 209 SFYVNRLSS------LVIQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRTPA---- 258
           +  V R+          +    KEI+ K+E ++      I  S     R SP  PA    
Sbjct: 445 AITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP-VPAQIAI 503

Query: 259 ------------SKIASEMAYEAVELTAAEMRGTGE--ESREGGQKSFLYSELS----NK 300
                       ++   EM    +EL A E     +  ES +       + E       K
Sbjct: 504 TVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKK 563

Query: 301 SKSGDKQMSQRES-KEFADSISKGLMVYANQVASD 334
            K+ ++   + E  +  A+S+S+G  + AN  ++D
Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTD 598


>gi|121582460 hypothetical protein LOC79762 [Homo sapiens]
          Length = 142

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 13/40 (32%), Positives = 21/40 (52%)

Query: 704 KYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQ 743
           +Y+++  A AE    AA    P  RG R +H   +P+ Y+
Sbjct: 40  EYADEAEAAAESGTSAADERGPGTRGARRVHFALLPERYE 79


>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
          Length = 2649

 Score = 30.8 bits (68), Expect = 5.5
 Identities = 54/252 (21%), Positives = 94/252 (37%), Gaps = 37/252 (14%)

Query: 224  HKEIK--EKLEGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTG 281
            HK+ K  +  + K KCL   +  S         +     I  +   + V    AE+  + 
Sbjct: 1633 HKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASK 1692

Query: 282  EESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMK 341
            EE R G QK                Q+ Q + +E  + + K       +   + M     
Sbjct: 1693 EEKRRGEQK---------------VQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1737

Query: 342  TLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRN 401
             L    SGK        K+      K+ +  L++S +   ++I+G+ +   DFVS  + N
Sbjct: 1738 VLFQEESGK-------FKQSAEEFRKK-MEKLMESKVITENDISGIRL---DFVSLQQEN 1786

Query: 402  LFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTM 461
              ++ ++NA  + E  +K L   L     +   + +        +H  KC+    E    
Sbjct: 1787 --SRAQENA-KLCETNIKELERQL-----QQYREQMQQGQHMEANHYQKCQKLEDELIAQ 1838

Query: 462  KAEMKERDKGKM 473
            K E+ E  K KM
Sbjct: 1839 KREV-ENLKQKM 1849


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 30.8 bits (68), Expect = 5.5
 Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 24/180 (13%)

Query: 83  KTEGSVCLFKQAPSDPVS----VLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEY 138
           K    +  F   P  P S     +N   SDL+K + G   +LSPS       V  T G  
Sbjct: 701 KDRSGIETFSPPPPPPKSRHLLKMNKSSSDLEKVSQGSAESLSPSFRGVH--VSFTTGST 758

Query: 139 HRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAA----KNTNNNQSPSAPPAKPPSTQR 194
              +S++     +D      L + P N   ++ A       +  + SPS P   PP  Q+
Sbjct: 759 DSLASDS--RTCSDGGPSSELAHSPTNSGKKLFAPVPFPSGSTEDVSPSGPQQPPPLPQK 816

Query: 195 AVISPDGECSIDDLSFYVN-----RLSSLVIQMAHKEIKEKLEGKSKCLHHSICPSPGNK 249
            ++S     S  D  F+         +S  + ++H E     E      H S   SPGN+
Sbjct: 817 KIVS--RAASSPDGFFWTQGSPKPGTASPKLNLSHSETNVHDES-----HFSYSLSPGNR 869


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,765,290
Number of Sequences: 37866
Number of extensions: 1398076
Number of successful extensions: 4501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 4431
Number of HSP's gapped (non-prelim): 109
length of query: 845
length of database: 18,247,518
effective HSP length: 111
effective length of query: 734
effective length of database: 14,044,392
effective search space: 10308583728
effective search space used: 10308583728
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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