BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] (845 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] 1683 0.0 gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] 1683 0.0 gi|21493041 A-kinase anchor protein 3 [Homo sapiens] 362 e-100 gi|217416354 sphingosine kinase type 1-interacting protein isofo... 57 7e-08 gi|217416352 sphingosine kinase type 1-interacting protein isofo... 56 1e-07 gi|7706457 A-kinase anchor protein 11 [Homo sapiens] 52 3e-06 gi|89213250 intermediate filament family orphan isoform 4 [Homo ... 35 0.22 gi|11968023 zinc finger protein 106 homolog [Homo sapiens] 35 0.22 gi|4758650 kinesin family member 5C [Homo sapiens] 34 0.50 gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 34 0.65 gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 33 1.1 gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] 33 1.4 gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] 33 1.4 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 32 1.9 gi|111548668 zinc finger protein 676 [Homo sapiens] 32 2.5 gi|110349721 titin isoform novex-3 [Homo sapiens] 32 3.2 gi|110349719 titin isoform N2-A [Homo sapiens] 32 3.2 gi|110349717 titin isoform novex-2 [Homo sapiens] 32 3.2 gi|110349713 titin isoform novex-1 [Homo sapiens] 32 3.2 gi|110349715 titin isoform N2-B [Homo sapiens] 32 3.2 gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 32 3.2 gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 31 4.2 gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ... 31 4.2 gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 31 4.2 gi|209862748 ataxin 3-like [Homo sapiens] 31 4.2 gi|31982909 zinc finger protein 394 [Homo sapiens] 31 4.2 gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 31 4.2 gi|121582460 hypothetical protein LOC79762 [Homo sapiens] 31 4.2 gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 31 5.5 gi|157909822 pragmin [Homo sapiens] 31 5.5 >gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] Length = 845 Score = 1683 bits (4358), Expect = 0.0 Identities = 845/845 (100%), Positives = 845/845 (100%) Query: 1 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL Sbjct: 1 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60 Query: 61 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL Sbjct: 61 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120 Query: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ Sbjct: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180 Query: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH Sbjct: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240 Query: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK Sbjct: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300 Query: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR Sbjct: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360 Query: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR Sbjct: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420 Query: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS Sbjct: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480 Query: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL Sbjct: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540 Query: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP Sbjct: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600 Query: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR Sbjct: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660 Query: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA Sbjct: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720 Query: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP Sbjct: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780 Query: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW Sbjct: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840 Query: 841 LLANL 845 LLANL Sbjct: 841 LLANL 845 >gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] Length = 854 Score = 1683 bits (4358), Expect = 0.0 Identities = 845/845 (100%), Positives = 845/845 (100%) Query: 1 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL Sbjct: 10 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 69 Query: 61 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL Sbjct: 70 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 129 Query: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ Sbjct: 130 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 189 Query: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH Sbjct: 190 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 249 Query: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK Sbjct: 250 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 309 Query: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR Sbjct: 310 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 369 Query: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR Sbjct: 370 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 429 Query: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS Sbjct: 430 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 489 Query: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL Sbjct: 490 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 549 Query: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP Sbjct: 550 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 609 Query: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR Sbjct: 610 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 669 Query: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA Sbjct: 670 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 729 Query: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP Sbjct: 730 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 789 Query: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW Sbjct: 790 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 849 Query: 841 LLANL 845 LLANL Sbjct: 850 LLANL 854 >gi|21493041 A-kinase anchor protein 3 [Homo sapiens] Length = 853 Score = 362 bits (930), Expect = e-100 Identities = 300/876 (34%), Positives = 432/876 (49%), Gaps = 184/876 (21%) Query: 96 SDPVSVLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVN 155 +DPV VL+WL DL+K FQ + + ++ G+ H+ S + Y+ Sbjct: 36 TDPVRVLSWLRRDLEKSTAEFQDVRFKPGESFGGETSNS-GDPHKGFSVDYYNTTTK--- 91 Query: 156 IDYLMNRPQNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRL 215 P+ L EMT + P + P Q S S+D++SFY NRL Sbjct: 92 -----GTPERLHFEMTHKEI----------PCQGPRAQLGNGS-----SVDEVSFYANRL 131 Query: 216 SSLVIQMAHKEIKEKLEG-KSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVEL-- 272 ++LVI MA KEI EK++G ++KC++ S+ GN+ +P SKIASE+ E V Sbjct: 132 TNLVIAMARKEINEKIDGSENKCVYQSLYM--GNEP--TPTKSLSKIASELVNETVSACS 187 Query: 273 -TAAEMRGTGEESREGG--------------------------------QKSFLYSELSN 299 AA + G R G +KSF Y E+ Sbjct: 188 RNAAPDKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQGPDDKPPSKKSFFYKEVF- 246 Query: 300 KSKSGD--------------KQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKV 345 +S++GD + Q +F S+S+G+M YAN V SDMMVS+MKTLK+ Sbjct: 247 ESRNGDYAREGGRFFPRERKRFRGQERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKI 306 Query: 346 HSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQ 405 I A+++LK+VLL+H KE+VSDLIDS ++NLH++TG LMTD+ FVSAVKR +F+ Sbjct: 307 QVKDTTI-ATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSH 365 Query: 406 WKQNATDIMEAMLKRLVSALIGE-------EKETKSQSLSYASLKAGSHDPKCRNQSLEF 458 Q ATDIM+AML++L + + + + + K++S S S+K G DPK RN + Sbjct: 366 GSQKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMK-GMGDPKNRNVNF-- 422 Query: 459 STMKAEMKERDKGKMKSDP-CKSLTSAEKVGEHILKEGLTIWNQKQGNSCK--------- 508 MK+E K R+ KM S+P + T A+ +GEHI+KEGLT+W++ Q CK Sbjct: 423 -AMKSETKLRE--KMYSEPKSEEETCAKTLGEHIIKEGLTLWHKTQQKECKSLGFQHAAF 479 Query: 509 ----VATKACSN-----------------KDEKGEKINASTDSLAKDLIVSALKLIQYHL 547 K S+ EK E +DS A+DLIVSAL LIQYHL Sbjct: 480 EAPNTQRKPASDISFEYPEDIGNLSLPPYPPEKPENFMYDSDSWAEDLIVSALLLIQYHL 539 Query: 548 TQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKEN 607 Q + + G+T A V ES P +E Sbjct: 540 AQGGRRDARSFVEAAGTT---------------NFPANEPPVAPDESCLKSAPIVGDQE- 583 Query: 608 QHLDSQKMDMSNIVLMLIQKLLNENPFK---------CEDPCEGENK-CSEPRASKAASM 657 ++K D+ ++ I+ LL+E FK E P + + K C P AS + Sbjct: 584 ---QAEKKDLRSVFFNFIRNLLSETIFKRDQSPEPKVPEQPVKEDRKLCERPLASSPPRL 640 Query: 658 SNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAEL-E 716 D+ ++ + +GQ ++ L+ SVMKLC+I+AK + A+LAEL + Sbjct: 641 -YEDDETPGALSGLTKMAVSQIDGHMSGQMVEHLMNSVMKLCVIIAKSCD--ASLAELGD 697 Query: 717 EQAASANKPN------------FRGT-----------RCIHS---GAMPQNYQDSLGHEV 750 +++ A++ +GT + IH+ G Q + V Sbjct: 698 DKSGDASRLTSAFPDSLYECLPAKGTGSAEAVLQNAYQAIHNEMRGTSGQPPEGCAAPTV 757 Query: 751 IVNNQCSTNSLQ-KQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 809 IV+N T+++Q KQLQAVLQW+AAS+ NVP+LYF GD +G EKL Q+SA A +KG SV Sbjct: 758 IVSNHNLTDTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSV 817 Query: 810 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLANL 845 G +LQ V+++ KERQ +EAVG V QLLDWL+ NL Sbjct: 818 GEVLQSVLRYEKERQLNEAVGNVTPLQLLDWLMVNL 853 Score = 44.3 bits (103), Expect = 5e-04 Identities = 18/32 (56%), Positives = 24/32 (75%) Query: 1 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKV 32 MS+ +DWL+S GVCKVD+Y+P Q QD K+ Sbjct: 1 MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKM 32 >gi|217416354 sphingosine kinase type 1-interacting protein isoform 1 [Homo sapiens] Length = 1700 Score = 57.0 bits (136), Expect = 7e-08 Identities = 64/290 (22%), Positives = 109/290 (37%), Gaps = 35/290 (12%) Query: 559 EDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMS 618 E C G ++++S+ E+ G + K ++ + S CQ + LD++ + + Sbjct: 1437 EACAGEPEPFLSKSSLLEEAEGHSNDK--NIPDVVRGGDTAVSACQIHSDSLDTRDVPEA 1494 Query: 619 NIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQ--ELDC 676 + D SE ++N D ++ Q E Sbjct: 1495 EA----------STEARAPDEAPNPPSSSEESTGSWTQLANEEDNPDDTSSFLQLSERSM 1544 Query: 677 TSGMKQANGQF----IDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRC 732 ++G A +D ES+ +I + E A A+ P GT Sbjct: 1545 SNGNSSATSSLGIMDLDIYQESMPSSPMINELVEEKKILKGQSESTEAPASGPP-TGT-- 1601 Query: 733 IHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQL 792 A PQ SL +++N +L+A LQWIAAS+ +P +YF ++ ++ Sbjct: 1602 ----ASPQR---SL---LVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQENRI 1651 Query: 793 EKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLL 842 EK V K + VG + V+++ K + K R L DWLL Sbjct: 1652 EKFLDVVQLVHRKSWKVGDIFHAVVQYCKMHEEQ----KDGRLSLFDWLL 1697 >gi|217416352 sphingosine kinase type 1-interacting protein isoform 2 [Homo sapiens] Length = 1671 Score = 56.2 bits (134), Expect = 1e-07 Identities = 68/284 (23%), Positives = 112/284 (39%), Gaps = 52/284 (18%) Query: 559 EDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMS 618 E C G ++++S+ E+ G + K ++ + S CQ + LD++ + + Sbjct: 1437 EACAGEPEPFLSKSSLLEEAEGHSNDK--NIPDVVRGGDTAVSACQIHSDSLDTRDVPEA 1494 Query: 619 NIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTS 678 E + P E N P +S S + + A E+ D TS Sbjct: 1495 ------------EASTEARAPDEAPN----PPSSSEESTGSWTQLANEE----DNPDDTS 1534 Query: 679 GMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAM 738 Q + + + +LVE L + E A A+ P GT A Sbjct: 1535 SFLQLSERSMSELVEEKKIL-------------KGQSESTEAPASGPP-TGT------AS 1574 Query: 739 PQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQV 798 PQ SL +++N +L+A LQWIAAS+ +P +YF ++ ++EK V Sbjct: 1575 PQR---SL---LVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQENRIEKFLDV 1628 Query: 799 SAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLL 842 K + VG + V+++ K + K R L DWLL Sbjct: 1629 VQLVHRKSWKVGDIFHAVVQYCKMHEEQ----KDGRLSLFDWLL 1668 >gi|7706457 A-kinase anchor protein 11 [Homo sapiens] Length = 1901 Score = 51.6 bits (122), Expect = 3e-06 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 5/95 (5%) Query: 750 VIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 809 +I N ++ QL+ +LQW+ AS+ V LYF D ++ +S + EKG+ V Sbjct: 1811 LITNIDMEPCTVDPQLRIILQWLIASEAEVAELYF---HDSANKEFMLLSKQLQEKGWKV 1867 Query: 810 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLAN 844 G LLQ V+++ + ++A + K L DWLL N Sbjct: 1868 GDLLQAVLQYYEVM--EKASSEERCKSLFDWLLEN 1900 Score = 39.3 bits (90), Expect = 0.015 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 9/85 (10%) Query: 59 NLNLGSLEEKEIIVIKDTEKK--------DQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQ 110 +L+ SL E EII +K+ K +QS G +C+ + +P+ P ++++ S L Sbjct: 87 SLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLS 146 Query: 111 KYALGFQHALSPSTSTCKHKVGDTE 135 KYA G ++ L KH++ T+ Sbjct: 147 KYATGIRYTLDTFLHQ-KHQLETTD 170 >gi|89213250 intermediate filament family orphan isoform 4 [Homo sapiens] Length = 563 Score = 35.4 bits (80), Expect = 0.22 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 13/133 (9%) Query: 407 KQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKA--E 464 ++N D+++ K+LV ++ G ++E K+ SL S P+ + E ST + E Sbjct: 346 QRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSE-SEGPRQPDGDEEESTALSINE 404 Query: 465 MKERDKGKMKS----DPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEK 520 +R +++ D C SLT E +E L +W G + A +++ Sbjct: 405 EMQRMLNQLREYDFEDDCDSLTWEET------EETLLLWEDFSGYAMAAAEAQGEQQEDS 458 Query: 521 GEKINASTDSLAK 533 EK+ T+SL K Sbjct: 459 LEKVIKDTESLFK 471 >gi|11968023 zinc finger protein 106 homolog [Homo sapiens] Length = 1883 Score = 35.4 bits (80), Expect = 0.22 Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 20/123 (16%) Query: 581 GQSAKA-LSVKQLESHRAPGPSTCQK-EN---QHLDSQKMDMSNIV-LMLIQKLLNEN-- 632 GQS KA + +KQ + RA T ++ EN Q S ++ +I+ LM + K LN Sbjct: 901 GQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQER 960 Query: 633 ---PFKCEDPCE--GENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQF 687 P + ++ E GE C AS A ++S+ +D A + CTSG +Q +GQ Sbjct: 961 SIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDS-------SCTSGAEQNDGQS 1013 Query: 688 IDK 690 I K Sbjct: 1014 IRK 1016 >gi|4758650 kinesin family member 5C [Homo sapiens] Length = 957 Score = 34.3 bits (77), Expect = 0.50 Identities = 72/386 (18%), Positives = 142/386 (36%), Gaps = 55/386 (14%) Query: 400 RNLFNQWKQNATDIMEAMLKRL--VSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLE 457 + L N K+ AT+I+ +LK L + +IG ++ G + + L Sbjct: 537 QELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVN------GVIEEEFTMARLY 590 Query: 458 FSTMKAEMKER-DKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSN 516 S MK+E+K ++ K E L + +Q + K T N Sbjct: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEA-KIKSLTDYMQN 649 Query: 517 KDEKGEKINASTDSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYE 576 ++K ++ S DSL+++L + + ++ Q K K+ Sbjct: 650 MEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKE------------------HLT 691 Query: 577 KCGGGQSAKALSVKQLESHRAPGPSTCQK------ENQHLDSQKMDMSNIVLMLIQKLLN 630 + + K +Q+ESHR + E Q + + D++ + + +KL + Sbjct: 692 RLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSS 751 Query: 631 E-NPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFID 689 + N K ED + R K + +DK E+ ++ + L+ T + + Sbjct: 752 DYNKLKIED---------QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLR 802 Query: 690 KL-VESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGH 748 KL V+ + + ND + ++Q S + N +H + N Sbjct: 803 KLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDN------- 855 Query: 749 EVIVNNQCSTNSLQKQLQAVLQWIAA 774 + +C L+K+L+A + + A Sbjct: 856 ---ADLRCELPKLEKRLRATAERVKA 878 >gi|56676335 RAP1 interacting factor 1 [Homo sapiens] Length = 2472 Score = 33.9 bits (76), Expect = 0.65 Identities = 72/378 (19%), Positives = 151/378 (39%), Gaps = 42/378 (11%) Query: 277 MRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYAN------- 329 + GT SR G+ +E + +S K + + E ++ + +G++V N Sbjct: 1281 VNGTKRSSRRAGK-----AEQTGNKRS--KPLMRSEPEKNTEESVEGIVVLENNPPGLLN 1333 Query: 330 --QVASDMMVSLMKTLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGV 387 + SD V L ++ H + K + A+ V VLL T + ++ +++ N V Sbjct: 1334 QTECVSDNQVHLSESTMEHDNTK-LKAATVENAVLLE-TNTVEEKNVEINLESKENTPPV 1391 Query: 388 LMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSH 447 +++ V+ + Q N + + +R S ++ E T+SQ K SH Sbjct: 1392 VISADQMVNEDSQV---QITPNQKTLRRSSRRR--SEVV--ESTTESQD------KENSH 1438 Query: 448 DPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSC 507 K R + E K+ + +D P + L + + + E+++++G + + G + Sbjct: 1439 QKKERRKEEEKPLQKSPLHIKDDVL----PKQKLIAEQTLQENLIEKGSNLHEKTLGETS 1494 Query: 508 KVATKACSNKDEKGEKINASTDSLAKDLIVSALKLI----QYHLTQQTKGKDTCEEDCPG 563 A + K E I + D + S+ KL+ +Y + ++G + E+ Sbjct: 1495 ANAETEQNKKKADPENIKSEGDGTQDIVDKSSEKLVRGRTRYQTRRASQGLLSSIENSES 1554 Query: 564 STMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQK-ENQHLDSQKMDMSNIVL 622 + + ++ ++ G ++ SV + C K ENQ D + ++ + Sbjct: 1555 DSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSI 1614 Query: 623 M--LIQKLLNENPFKCED 638 + +K N C+D Sbjct: 1615 KSPICEKQDESNTVICQD 1632 >gi|56676397 ankyrin repeat domain 11 [Homo sapiens] Length = 2663 Score = 33.1 bits (74), Expect = 1.1 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 3/86 (3%) Query: 175 NTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGK 234 N N+ +PS P K + R + DG+ + +++ L I+ HK KE+++ Sbjct: 1550 NGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQ-KDLEIEERHKRHKERMKQM 1608 Query: 235 SKCLHHSICPSPGNKERISPRTPASK 260 K H S P KE+ P K Sbjct: 1609 EKLRHRS--GDPKLKEKAKPADDGRK 1632 >gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] Length = 2540 Score = 32.7 bits (73), Expect = 1.4 Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 21/138 (15%) Query: 400 RNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFS 459 ++L N+ ++ D + +KRL + + + E+ S + S + K N Sbjct: 346 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN------ 399 Query: 460 TMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDE 519 E+K ++ K+ + K + EK GE LK W+Q Q + K E Sbjct: 400 ----ELKNKNTSKINGEEGKPHNN-EKAGEETLKNSQPPWDQIQED----------KKHE 444 Query: 520 KGEKINASTDSLAKDLIV 537 + EK + L +D+I+ Sbjct: 445 EAEKRKSVDTQLQEDMII 462 >gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] Length = 2303 Score = 32.7 bits (73), Expect = 1.4 Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 21/138 (15%) Query: 400 RNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFS 459 ++L N+ ++ D + +KRL + + + E+ S + S + K N Sbjct: 127 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN------ 180 Query: 460 TMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDE 519 E+K ++ K+ + K + EK GE LK W+Q Q + K E Sbjct: 181 ----ELKNKNTSKINGEEGKPHNN-EKAGEETLKNSQPPWDQIQED----------KKHE 225 Query: 520 KGEKINASTDSLAKDLIV 537 + EK + L +D+I+ Sbjct: 226 EAEKRKSVDTQLQEDMII 243 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 32.3 bits (72), Expect = 1.9 Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Query: 608 QHLDSQKMDMSNIVLMLIQKLLN---ENPFKCEDP----CEGENKCSEPRASKAASMSNR 660 +H + K D + ++ L++++ N + + C+ P +G PR++ AA ++ Sbjct: 668 RHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTATAPPPRSNHAAEEASS 727 Query: 661 SDKAEEQCQEHQELDCT 677 D+ EE+ Q Q + T Sbjct: 728 EDEEEEEVQAMQSFNST 744 >gi|111548668 zinc finger protein 676 [Homo sapiens] Length = 588 Score = 32.0 bits (71), Expect = 2.5 Identities = 43/203 (21%), Positives = 71/203 (34%), Gaps = 28/203 (13%) Query: 483 SAEKVGEHILKEGLTIWNQKQGNSCKVAT--KACSNKDEKGEKINASTDSLAKDLIVSAL 540 + K G + L + LT K K A CSN + + K+ + S Sbjct: 92 NVHKEGYNKLNQSLTTTQSKVFQCGKYANVFHKCSNSNRHKIRHTGEKGLKCKEYVRSFC 151 Query: 541 KLIQYHLTQQTK-----GKDTCEEDCPGSTMGYMAQSTQY------------EKCGGGQS 583 L HL+Q + CEE+ G + + T Y E+CG S Sbjct: 152 MLS--HLSQHERIYTRENSYKCEEN--GKAFNWSSTLTYYKSIHTGEKPYKCEECGKAFS 207 Query: 584 AKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGE 643 ++ K H P C++ + + + + ++ E P+KCE+ +G Sbjct: 208 KFSILTKHKVIHTGEKPYKCEECGKAFNRSSILTKHKIIHT-----GEKPYKCEECGKGF 262 Query: 644 NKCSEPRASKAASMSNRSDKAEE 666 + S KA + K EE Sbjct: 263 SSVSTLNTHKAIHAEEKPYKCEE 285 >gi|110349721 titin isoform novex-3 [Homo sapiens] Length = 5604 Score = 31.6 bits (70), Expect = 3.2 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 38 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91 VS N+E K Y + S G + S ++ + +KD K+DQ + + + C Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349 Query: 92 KQAPSDPVSVLNWL 105 K P P+++L L Sbjct: 2350 KMKPR-PIAILQGL 2362 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 31.6 bits (70), Expect = 3.2 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 38 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91 VS N+E K Y + S G + S ++ + +KD K+DQ + + + C Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349 Query: 92 KQAPSDPVSVLNWL 105 K P P+++L L Sbjct: 2350 KMKPR-PIAILQGL 2362 >gi|110349717 titin isoform novex-2 [Homo sapiens] Length = 27118 Score = 31.6 bits (70), Expect = 3.2 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 38 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91 VS N+E K Y + S G + S ++ + +KD K+DQ + + + C Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303 Query: 92 KQAPSDPVSVLNWL 105 K P P+++L L Sbjct: 2304 KMKPR-PIAILQGL 2316 >gi|110349713 titin isoform novex-1 [Homo sapiens] Length = 27051 Score = 31.6 bits (70), Expect = 3.2 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 38 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91 VS N+E K Y + S G + S ++ + +KD K+DQ + + + C Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303 Query: 92 KQAPSDPVSVLNWL 105 K P P+++L L Sbjct: 2304 KMKPR-PIAILQGL 2316 >gi|110349715 titin isoform N2-B [Homo sapiens] Length = 26926 Score = 31.6 bits (70), Expect = 3.2 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 38 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 91 VS N+E K Y + S G + S ++ + +KD K+DQ + + + C Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303 Query: 92 KQAPSDPVSVLNWL 105 K P P+++L L Sbjct: 2304 KMKPR-PIAILQGL 2316 >gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] Length = 1352 Score = 31.6 bits (70), Expect = 3.2 Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 29/171 (16%) Query: 171 TAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEK 230 ++++ + + SP+ PA+P SP + S+ S + +S + A +K Sbjct: 1079 SSSRGSGRHSSPA--PAQPKKES----SPKSQDSVSSPSPQKQKSASALTYTASSTSAKK 1132 Query: 231 LEG----------KSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGT 280 G KS+ HS+ + S R A+ + + + A E RG Sbjct: 1133 ASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTSKPNSPRVSQARAGEGRGA 1192 Query: 281 GEESREGGQKSF------LYSELSNKSKSGDKQMS-------QRESKEFAD 318 G+ R S + S L SKS DK +S Q+E++ D Sbjct: 1193 GKHVRSSSMASLRSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKETRRSTD 1243 >gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo sapiens] Length = 1198 Score = 31.2 bits (69), Expect = 4.2 Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%) Query: 23 EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 82 EG++D+D + D +Y + + + + G E + + + ++ Sbjct: 893 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 941 Query: 83 KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 138 +EGS+ Q P P SD + + A S PS ST K ++G G Sbjct: 942 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 993 Query: 139 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 190 H S + + AD V D +R + + KN N+SP APPA Sbjct: 994 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 1053 Query: 191 STQRAVISPDGE 202 P E Sbjct: 1054 DKMMKSFKPTSE 1065 >gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo sapiens] Length = 519 Score = 31.2 bits (69), Expect = 4.2 Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%) Query: 23 EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 82 EG++D+D + D +Y + + + + G E + + + ++ Sbjct: 214 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 262 Query: 83 KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 138 +EGS+ Q P P SD + + A S PS ST K ++G G Sbjct: 263 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 314 Query: 139 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 190 H S + + AD V D +R + + KN N+SP APPA Sbjct: 315 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 374 Query: 191 STQRAVISPDGE 202 P E Sbjct: 375 DKMMKSFKPTSE 386 >gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo sapiens] Length = 917 Score = 31.2 bits (69), Expect = 4.2 Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%) Query: 23 EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 82 EG++D+D + D +Y + + + + G E + + + ++ Sbjct: 612 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 660 Query: 83 KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 138 +EGS+ Q P P SD + + A S PS ST K ++G G Sbjct: 661 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 712 Query: 139 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 190 H S + + AD V D +R + + KN N+SP APPA Sbjct: 713 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 772 Query: 191 STQRAVISPDGE 202 P E Sbjct: 773 DKMMKSFKPTSE 784 >gi|209862748 ataxin 3-like [Homo sapiens] Length = 355 Score = 31.2 bits (69), Expect = 4.2 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 17/131 (12%) Query: 220 IQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRT----PASKIASEMAYEAVELTAA 275 ++++ +E + E + S+ S GN + P+T PAS+ ++ + E Sbjct: 233 LELSRQETNREDEHLRSTIELSMQGSSGNTSQDLPKTSCVTPASEQPKKIKEDYFEKHQQ 292 Query: 276 EMRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDM 335 E + ++S G S+L+ + S++ + +S D IS+G + Q A D Sbjct: 293 EQKQQQQQSDLPGHSSYLHERPTTSSRAIESDLS--------DDISEGTV----QAAVDT 340 Query: 336 MVSLM-KTLKV 345 ++ +M K LK+ Sbjct: 341 ILEIMRKNLKI 351 >gi|31982909 zinc finger protein 394 [Homo sapiens] Length = 561 Score = 31.2 bits (69), Expect = 4.2 Identities = 42/190 (22%), Positives = 66/190 (34%), Gaps = 38/190 (20%) Query: 576 EKCGGGQSAKALSVKQLESHRAPGPSTCQK------ENQHLDSQKMDMSNIVLMLIQKLL 629 ++CG S A K +H P TC K +N HL+ + S Sbjct: 389 QECGKSFSQSAALTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHS----------- 437 Query: 630 NENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEE--QCQEHQELDCTSGMKQANGQF 687 + FKCE+ C E R K E +C+E C KQ + F Sbjct: 438 RDKHFKCEE-------CGETCHISNLFRHQRLHKGERPYKCEE-----CEKSFKQRSDLF 485 Query: 688 IDKLVESVMKL--CLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDS 745 + + K C + K N A L + ++ + KP +C+ G + Sbjct: 486 KHHRIHTGEKPYGCSVCGKRFNQSATLIK-HQRIHTGEKP----YKCLECGERFRQSTHL 540 Query: 746 LGHEVIVNNQ 755 + H+ I N+ Sbjct: 541 IRHQRIHQNK 550 >gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo sapiens] Length = 1585 Score = 31.2 bits (69), Expect = 4.2 Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 35/215 (16%) Query: 154 VNIDYLMNRPQNLRLEMTAAKNTNNN-----QSPSAPPAKPPSTQRAVISPDGECSIDDL 208 + ++ L N P+ ++LE A T + +P PPA PP T V + S Sbjct: 385 LELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSA 444 Query: 209 SFYVNRLSS------LVIQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRTPA---- 258 + V R+ + KEI+ K+E ++ I S R SP PA Sbjct: 445 AITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP-VPAQIAI 503 Query: 259 ------------SKIASEMAYEAVELTAAEMRGTGE--ESREGGQKSFLYSELS----NK 300 ++ EM +EL A E + ES + + E K Sbjct: 504 TVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKK 563 Query: 301 SKSGDKQMSQRES-KEFADSISKGLMVYANQVASD 334 K+ ++ + E + A+S+S+G + AN ++D Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTD 598 >gi|121582460 hypothetical protein LOC79762 [Homo sapiens] Length = 142 Score = 31.2 bits (69), Expect = 4.2 Identities = 13/40 (32%), Positives = 21/40 (52%) Query: 704 KYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQ 743 +Y+++ A AE AA P RG R +H +P+ Y+ Sbjct: 40 EYADEAEAAAESGTSAADERGPGTRGARRVHFALLPERYE 79 >gi|4502443 dystonin isoform 1e precursor [Homo sapiens] Length = 2649 Score = 30.8 bits (68), Expect = 5.5 Identities = 54/252 (21%), Positives = 94/252 (37%), Gaps = 37/252 (14%) Query: 224 HKEIK--EKLEGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTG 281 HK+ K + + K KCL + S + I + + V AE+ + Sbjct: 1633 HKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASK 1692 Query: 282 EESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMK 341 EE R G QK Q+ Q + +E + + K + + M Sbjct: 1693 EEKRRGEQK---------------VQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1737 Query: 342 TLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRN 401 L SGK K+ K+ + L++S + ++I+G+ + DFVS + N Sbjct: 1738 VLFQEESGK-------FKQSAEEFRKK-MEKLMESKVITENDISGIRL---DFVSLQQEN 1786 Query: 402 LFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTM 461 ++ ++NA + E +K L L + + + +H KC+ E Sbjct: 1787 --SRAQENA-KLCETNIKELERQL-----QQYREQMQQGQHMEANHYQKCQKLEDELIAQ 1838 Query: 462 KAEMKERDKGKM 473 K E+ E K KM Sbjct: 1839 KREV-ENLKQKM 1849 >gi|157909822 pragmin [Homo sapiens] Length = 1402 Score = 30.8 bits (68), Expect = 5.5 Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 24/180 (13%) Query: 83 KTEGSVCLFKQAPSDPVS----VLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEY 138 K + F P P S +N SDL+K + G +LSPS V T G Sbjct: 701 KDRSGIETFSPPPPPPKSRHLLKMNKSSSDLEKVSQGSAESLSPSFRGVH--VSFTTGST 758 Query: 139 HRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAA----KNTNNNQSPSAPPAKPPSTQR 194 +S++ +D L + P N ++ A + + SPS P PP Q+ Sbjct: 759 DSLASDS--RTCSDGGPSSELAHSPTNSGKKLFAPVPFPSGSTEDVSPSGPQQPPPLPQK 816 Query: 195 AVISPDGECSIDDLSFYVN-----RLSSLVIQMAHKEIKEKLEGKSKCLHHSICPSPGNK 249 ++S S D F+ +S + ++H E E H S SPGN+ Sbjct: 817 KIVS--RAASSPDGFFWTQGSPKPGTASPKLNLSHSETNVHDES-----HFSYSLSPGNR 869 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.126 0.355 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,765,290 Number of Sequences: 37866 Number of extensions: 1398076 Number of successful extensions: 4501 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 4431 Number of HSP's gapped (non-prelim): 109 length of query: 845 length of database: 18,247,518 effective HSP length: 111 effective length of query: 734 effective length of database: 14,044,392 effective search space: 10308583728 effective search space used: 10308583728 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.