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Search of human proteins with 21493037
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
(854 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens] 1701 0.0
gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens] 1683 0.0
gi|21493041 A-kinase anchor protein 3 [Homo sapiens] 362 e-100
gi|217416354 sphingosine kinase type 1-interacting protein isofo... 57 7e-08
gi|217416352 sphingosine kinase type 1-interacting protein isofo... 56 1e-07
gi|7706457 A-kinase anchor protein 11 [Homo sapiens] 52 3e-06
gi|89213250 intermediate filament family orphan isoform 4 [Homo ... 35 0.23
gi|11968023 zinc finger protein 106 homolog [Homo sapiens] 35 0.23
gi|4758650 kinesin family member 5C [Homo sapiens] 34 0.50
gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 34 0.66
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 33 1.1
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] 33 1.5
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] 33 1.5
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 32 1.9
gi|111548668 zinc finger protein 676 [Homo sapiens] 32 2.5
gi|110349721 titin isoform novex-3 [Homo sapiens] 32 3.3
gi|110349719 titin isoform N2-A [Homo sapiens] 32 3.3
gi|110349717 titin isoform novex-2 [Homo sapiens] 32 3.3
gi|110349713 titin isoform novex-1 [Homo sapiens] 32 3.3
gi|110349715 titin isoform N2-B [Homo sapiens] 32 3.3
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 32 3.3
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 31 4.3
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ... 31 4.3
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ... 31 4.3
gi|209862748 ataxin 3-like [Homo sapiens] 31 4.3
gi|31982909 zinc finger protein 394 [Homo sapiens] 31 4.3
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 31 4.3
gi|121582460 hypothetical protein LOC79762 [Homo sapiens] 31 4.3
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 31 5.6
gi|157909822 pragmin [Homo sapiens] 31 5.6
>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
Length = 854
Score = 1701 bits (4404), Expect = 0.0
Identities = 854/854 (100%), Positives = 854/854 (100%)
Query: 1 MMAYSDTTMMSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDA 60
MMAYSDTTMMSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDA
Sbjct: 1 MMAYSDTTMMSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDA 60
Query: 61 ASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQK 120
ASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQK
Sbjct: 61 ASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQK 120
Query: 121 YALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMT 180
YALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMT
Sbjct: 121 YALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMT 180
Query: 181 AAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKL 240
AAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKL
Sbjct: 181 AAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKL 240
Query: 241 EGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKS 300
EGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKS
Sbjct: 241 EGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKS 300
Query: 301 FLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKP 360
FLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKP
Sbjct: 301 FLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKP 360
Query: 361 IPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNAT 420
IPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNAT
Sbjct: 361 IPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNAT 420
Query: 421 DIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKG 480
DIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKG
Sbjct: 421 DIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKG 480
Query: 481 KMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSL 540
KMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSL
Sbjct: 481 KMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSL 540
Query: 541 AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQ 600
AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQ
Sbjct: 541 AKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQ 600
Query: 601 LESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRA 660
LESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRA
Sbjct: 601 LESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRA 660
Query: 661 SKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAA 720
SKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAA
Sbjct: 661 SKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAA 720
Query: 721 LAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQW 780
LAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQW
Sbjct: 721 LAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQW 780
Query: 781 IAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGK 840
IAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGK
Sbjct: 781 IAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGK 840
Query: 841 VARKQLLDWLLANL 854
VARKQLLDWLLANL
Sbjct: 841 VARKQLLDWLLANL 854
>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
Length = 845
Score = 1683 bits (4358), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 10 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 69
MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL
Sbjct: 1 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNL 60
Query: 70 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 129
NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL
Sbjct: 61 NLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHAL 120
Query: 130 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 189
SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ
Sbjct: 121 SPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQ 180
Query: 190 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 249
SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH
Sbjct: 181 SPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHH 240
Query: 250 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 309
SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK
Sbjct: 241 SICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNK 300
Query: 310 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 369
SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR
Sbjct: 301 SKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKR 360
Query: 370 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 429
VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR
Sbjct: 361 VLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKR 420
Query: 430 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 489
LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS
Sbjct: 421 LVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKS 480
Query: 490 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 549
LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL
Sbjct: 481 LTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSAL 540
Query: 550 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 609
KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP
Sbjct: 541 KLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGP 600
Query: 610 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 669
STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR
Sbjct: 601 STCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNR 660
Query: 670 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 729
SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA
Sbjct: 661 SDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAA 720
Query: 730 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 789
SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP
Sbjct: 721 SANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVP 780
Query: 790 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 849
MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW
Sbjct: 781 MLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDW 840
Query: 850 LLANL 854
LLANL
Sbjct: 841 LLANL 845
>gi|21493041 A-kinase anchor protein 3 [Homo sapiens]
Length = 853
Score = 362 bits (930), Expect = e-100
Identities = 300/876 (34%), Positives = 432/876 (49%), Gaps = 184/876 (21%)
Query: 105 SDPVSVLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVN 164
+DPV VL+WL DL+K FQ + + ++ G+ H+ S + Y+
Sbjct: 36 TDPVRVLSWLRRDLEKSTAEFQDVRFKPGESFGGETSNS-GDPHKGFSVDYYNTTTK--- 91
Query: 165 IDYLMNRPQNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRL 224
P+ L EMT + P + P Q S S+D++SFY NRL
Sbjct: 92 -----GTPERLHFEMTHKEI----------PCQGPRAQLGNGS-----SVDEVSFYANRL 131
Query: 225 SSLVIQMAHKEIKEKLEG-KSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVEL-- 281
++LVI MA KEI EK++G ++KC++ S+ GN+ +P SKIASE+ E V
Sbjct: 132 TNLVIAMARKEINEKIDGSENKCVYQSLYM--GNEP--TPTKSLSKIASELVNETVSACS 187
Query: 282 -TAAEMRGTGEESREGG--------------------------------QKSFLYSELSN 308
AA + G R G +KSF Y E+
Sbjct: 188 RNAAPDKAPGSGDRVSGSSQSPPNLKYKSTLKIKESTKERQGPDDKPPSKKSFFYKEVF- 246
Query: 309 KSKSGD--------------KQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKV 354
+S++GD + Q +F S+S+G+M YAN V SDMMVS+MKTLK+
Sbjct: 247 ESRNGDYAREGGRFFPRERKRFRGQERPDDFTASVSEGIMTYANSVVSDMMVSIMKTLKI 306
Query: 355 HSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQ 414
I A+++LK+VLL+H KE+VSDLIDS ++NLH++TG LMTD+ FVSAVKR +F+
Sbjct: 307 QVKDTTI-ATILLKKVLLKHAKEVVSDLIDSFLRNLHSVTGTLMTDTQFVSAVKRTVFSH 365
Query: 415 WKQNATDIMEAMLKRLVSALIGE-------EKETKSQSLSYASLKAGSHDPKCRNQSLEF 467
Q ATDIM+AML++L + + + + + K++S S S+K G DPK RN +
Sbjct: 366 GSQKATDIMDAMLRKLYNVMFAKKVPEHVRKAQDKAESYSLISMK-GMGDPKNRNVNF-- 422
Query: 468 STMKAEMKERDKGKMKSDP-CKSLTSAEKVGEHILKEGLTIWNQKQGNSCK--------- 517
MK+E K R+ KM S+P + T A+ +GEHI+KEGLT+W++ Q CK
Sbjct: 423 -AMKSETKLRE--KMYSEPKSEEETCAKTLGEHIIKEGLTLWHKTQQKECKSLGFQHAAF 479
Query: 518 ----VATKACSN-----------------KDEKGEKINASTDSLAKDLIVSALKLIQYHL 556
K S+ EK E +DS A+DLIVSAL LIQYHL
Sbjct: 480 EAPNTQRKPASDISFEYPEDIGNLSLPPYPPEKPENFMYDSDSWAEDLIVSALLLIQYHL 539
Query: 557 TQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKEN 616
Q + + G+T A V ES P +E
Sbjct: 540 AQGGRRDARSFVEAAGTT---------------NFPANEPPVAPDESCLKSAPIVGDQE- 583
Query: 617 QHLDSQKMDMSNIVLMLIQKLLNENPFK---------CEDPCEGENK-CSEPRASKAASM 666
++K D+ ++ I+ LL+E FK E P + + K C P AS +
Sbjct: 584 ---QAEKKDLRSVFFNFIRNLLSETIFKRDQSPEPKVPEQPVKEDRKLCERPLASSPPRL 640
Query: 667 SNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAEL-E 725
D+ ++ + +GQ ++ L+ SVMKLC+I+AK + A+LAEL +
Sbjct: 641 -YEDDETPGALSGLTKMAVSQIDGHMSGQMVEHLMNSVMKLCVIIAKSCD--ASLAELGD 697
Query: 726 EQAASANKPN------------FRGT-----------RCIHS---GAMPQNYQDSLGHEV 759
+++ A++ +GT + IH+ G Q + V
Sbjct: 698 DKSGDASRLTSAFPDSLYECLPAKGTGSAEAVLQNAYQAIHNEMRGTSGQPPEGCAAPTV 757
Query: 760 IVNNQCSTNSLQ-KQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 818
IV+N T+++Q KQLQAVLQW+AAS+ NVP+LYF GD +G EKL Q+SA A +KG SV
Sbjct: 758 IVSNHNLTDTVQNKQLQAVLQWVAASELNVPILYFAGDDEGIQEKLLQLSAAAVDKGCSV 817
Query: 819 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLANL 854
G +LQ V+++ KERQ +EAVG V QLLDWL+ NL
Sbjct: 818 GEVLQSVLRYEKERQLNEAVGNVTPLQLLDWLMVNL 853
Score = 44.3 bits (103), Expect = 5e-04
Identities = 18/32 (56%), Positives = 24/32 (75%)
Query: 10 MSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKV 41
MS+ +DWL+S GVCKVD+Y+P Q QD K+
Sbjct: 1 MSEKVDWLQSQNGVCKVDVYSPGDNQAQDWKM 32
>gi|217416354 sphingosine kinase type 1-interacting protein isoform 1
[Homo sapiens]
Length = 1700
Score = 57.0 bits (136), Expect = 7e-08
Identities = 64/290 (22%), Positives = 109/290 (37%), Gaps = 35/290 (12%)
Query: 568 EDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMS 627
E C G ++++S+ E+ G + K ++ + S CQ + LD++ + +
Sbjct: 1437 EACAGEPEPFLSKSSLLEEAEGHSNDK--NIPDVVRGGDTAVSACQIHSDSLDTRDVPEA 1494
Query: 628 NIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQ--ELDC 685
+ D SE ++N D ++ Q E
Sbjct: 1495 EA----------STEARAPDEAPNPPSSSEESTGSWTQLANEEDNPDDTSSFLQLSERSM 1544
Query: 686 TSGMKQANGQF----IDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRC 741
++G A +D ES+ +I + E A A+ P GT
Sbjct: 1545 SNGNSSATSSLGIMDLDIYQESMPSSPMINELVEEKKILKGQSESTEAPASGPP-TGT-- 1601
Query: 742 IHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQL 801
A PQ SL +++N +L+A LQWIAAS+ +P +YF ++ ++
Sbjct: 1602 ----ASPQR---SL---LVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQENRI 1651
Query: 802 EKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLL 851
EK V K + VG + V+++ K + K R L DWLL
Sbjct: 1652 EKFLDVVQLVHRKSWKVGDIFHAVVQYCKMHEEQ----KDGRLSLFDWLL 1697
>gi|217416352 sphingosine kinase type 1-interacting protein isoform 2
[Homo sapiens]
Length = 1671
Score = 56.2 bits (134), Expect = 1e-07
Identities = 68/284 (23%), Positives = 112/284 (39%), Gaps = 52/284 (18%)
Query: 568 EDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMS 627
E C G ++++S+ E+ G + K ++ + S CQ + LD++ + +
Sbjct: 1437 EACAGEPEPFLSKSSLLEEAEGHSNDK--NIPDVVRGGDTAVSACQIHSDSLDTRDVPEA 1494
Query: 628 NIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTS 687
E + P E N P +S S + + A E+ D TS
Sbjct: 1495 ------------EASTEARAPDEAPN----PPSSSEESTGSWTQLANEE----DNPDDTS 1534
Query: 688 GMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAM 747
Q + + + +LVE L + E A A+ P GT A
Sbjct: 1535 SFLQLSERSMSELVEEKKIL-------------KGQSESTEAPASGPP-TGT------AS 1574
Query: 748 PQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQV 807
PQ SL +++N +L+A LQWIAAS+ +P +YF ++ ++EK V
Sbjct: 1575 PQR---SL---LVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQENRIEKFLDV 1628
Query: 808 SAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLL 851
K + VG + V+++ K + K R L DWLL
Sbjct: 1629 VQLVHRKSWKVGDIFHAVVQYCKMHEEQ----KDGRLSLFDWLL 1668
>gi|7706457 A-kinase anchor protein 11 [Homo sapiens]
Length = 1901
Score = 51.6 bits (122), Expect = 3e-06
Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 759 VIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSV 818
+I N ++ QL+ +LQW+ AS+ V LYF D ++ +S + EKG+ V
Sbjct: 1811 LITNIDMEPCTVDPQLRIILQWLIASEAEVAELYF---HDSANKEFMLLSKQLQEKGWKV 1867
Query: 819 GGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLAN 853
G LLQ V+++ + ++A + K L DWLL N
Sbjct: 1868 GDLLQAVLQYYEVM--EKASSEERCKSLFDWLLEN 1900
Score = 39.3 bits (90), Expect = 0.016
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 68 NLNLGSLEEKEIIVIKDTEKK--------DQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQ 119
+L+ SL E EII +K+ K +QS G +C+ + +P+ P ++++ S L
Sbjct: 87 SLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLS 146
Query: 120 KYALGFQHALSPSTSTCKHKVGDTE 144
KYA G ++ L KH++ T+
Sbjct: 147 KYATGIRYTLDTFLHQ-KHQLETTD 170
>gi|89213250 intermediate filament family orphan isoform 4 [Homo
sapiens]
Length = 563
Score = 35.4 bits (80), Expect = 0.23
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 13/133 (9%)
Query: 416 KQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKA--E 473
++N D+++ K+LV ++ G ++E K+ SL S P+ + E ST + E
Sbjct: 346 QRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSE-SEGPRQPDGDEEESTALSINE 404
Query: 474 MKERDKGKMKS----DPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEK 529
+R +++ D C SLT E +E L +W G + A +++
Sbjct: 405 EMQRMLNQLREYDFEDDCDSLTWEET------EETLLLWEDFSGYAMAAAEAQGEQQEDS 458
Query: 530 GEKINASTDSLAK 542
EK+ T+SL K
Sbjct: 459 LEKVIKDTESLFK 471
>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
Length = 1883
Score = 35.4 bits (80), Expect = 0.23
Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 20/123 (16%)
Query: 590 GQSAKA-LSVKQLESHRAPGPSTCQK-EN---QHLDSQKMDMSNIV-LMLIQKLLNEN-- 641
GQS KA + +KQ + RA T ++ EN Q S ++ +I+ LM + K LN
Sbjct: 901 GQSQKATMHLKQEVTPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQER 960
Query: 642 ---PFKCEDPCE--GENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQF 696
P + ++ E GE C AS A ++S+ +D A + CTSG +Q +GQ
Sbjct: 961 SIPPSENQNSQESNGEGNCLSSSASSALAISSLADAATDS-------SCTSGAEQNDGQS 1013
Query: 697 IDK 699
I K
Sbjct: 1014 IRK 1016
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 34.3 bits (77), Expect = 0.50
Identities = 72/386 (18%), Positives = 142/386 (36%), Gaps = 55/386 (14%)
Query: 409 RNLFNQWKQNATDIMEAMLKRL--VSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLE 466
+ L N K+ AT+I+ +LK L + +IG ++ G + + L
Sbjct: 537 QELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVN------GVIEEEFTMARLY 590
Query: 467 FSTMKAEMKER-DKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSN 525
S MK+E+K ++ K E L + +Q + K T N
Sbjct: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEA-KIKSLTDYMQN 649
Query: 526 KDEKGEKINASTDSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYE 585
++K ++ S DSL+++L + + ++ Q K K+
Sbjct: 650 MEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKE------------------HLT 691
Query: 586 KCGGGQSAKALSVKQLESHRAPGPSTCQK------ENQHLDSQKMDMSNIVLMLIQKLLN 639
+ + K +Q+ESHR + E Q + + D++ + + +KL +
Sbjct: 692 RLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSS 751
Query: 640 E-NPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFID 698
+ N K ED + R K + +DK E+ ++ + L+ T + +
Sbjct: 752 DYNKLKIED---------QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLR 802
Query: 699 KL-VESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGH 757
KL V+ + + ND + ++Q S + N +H + N
Sbjct: 803 KLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDN------- 855
Query: 758 EVIVNNQCSTNSLQKQLQAVLQWIAA 783
+ +C L+K+L+A + + A
Sbjct: 856 ---ADLRCELPKLEKRLRATAERVKA 878
>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
Length = 2472
Score = 33.9 bits (76), Expect = 0.66
Identities = 72/378 (19%), Positives = 151/378 (39%), Gaps = 42/378 (11%)
Query: 286 MRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYAN------- 338
+ GT SR G+ +E + +S K + + E ++ + +G++V N
Sbjct: 1281 VNGTKRSSRRAGK-----AEQTGNKRS--KPLMRSEPEKNTEESVEGIVVLENNPPGLLN 1333
Query: 339 --QVASDMMVSLMKTLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGV 396
+ SD V L ++ H + K + A+ V VLL T + ++ +++ N V
Sbjct: 1334 QTECVSDNQVHLSESTMEHDNTK-LKAATVENAVLLE-TNTVEEKNVEINLESKENTPPV 1391
Query: 397 LMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSH 456
+++ V+ + Q N + + +R S ++ E T+SQ K SH
Sbjct: 1392 VISADQMVNEDSQV---QITPNQKTLRRSSRRR--SEVV--ESTTESQD------KENSH 1438
Query: 457 DPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSC 516
K R + E K+ + +D P + L + + + E+++++G + + G +
Sbjct: 1439 QKKERRKEEEKPLQKSPLHIKDDVL----PKQKLIAEQTLQENLIEKGSNLHEKTLGETS 1494
Query: 517 KVATKACSNKDEKGEKINASTDSLAKDLIVSALKLI----QYHLTQQTKGKDTCEEDCPG 572
A + K E I + D + S+ KL+ +Y + ++G + E+
Sbjct: 1495 ANAETEQNKKKADPENIKSEGDGTQDIVDKSSEKLVRGRTRYQTRRASQGLLSSIENSES 1554
Query: 573 STMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQK-ENQHLDSQKMDMSNIVL 631
+ + ++ ++ G ++ SV + C K ENQ D + ++ +
Sbjct: 1555 DSSEAKEEGSRKKRSGKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSI 1614
Query: 632 M--LIQKLLNENPFKCED 647
+ +K N C+D
Sbjct: 1615 KSPICEKQDESNTVICQD 1632
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 33.1 bits (74), Expect = 1.1
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Query: 184 NTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGK 243
N N+ +PS P K + R + DG+ + +++ L I+ HK KE+++
Sbjct: 1550 NGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQ-KDLEIEERHKRHKERMKQM 1608
Query: 244 SKCLHHSICPSPGNKERISPRTPASK 269
K H S P KE+ P K
Sbjct: 1609 EKLRHRS--GDPKLKEKAKPADDGRK 1632
>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
Length = 2540
Score = 32.7 bits (73), Expect = 1.5
Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 21/138 (15%)
Query: 409 RNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFS 468
++L N+ ++ D + +KRL + + + E+ S + S + K N
Sbjct: 346 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN------ 399
Query: 469 TMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDE 528
E+K ++ K+ + K + EK GE LK W+Q Q + K E
Sbjct: 400 ----ELKNKNTSKINGEEGKPHNN-EKAGEETLKNSQPPWDQIQED----------KKHE 444
Query: 529 KGEKINASTDSLAKDLIV 546
+ EK + L +D+I+
Sbjct: 445 EAEKRKSVDTQLQEDMII 462
>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
Length = 2303
Score = 32.7 bits (73), Expect = 1.5
Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 21/138 (15%)
Query: 409 RNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFS 468
++L N+ ++ D + +KRL + + + E+ S + S + K N
Sbjct: 127 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN------ 180
Query: 469 TMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDE 528
E+K ++ K+ + K + EK GE LK W+Q Q + K E
Sbjct: 181 ----ELKNKNTSKINGEEGKPHNN-EKAGEETLKNSQPPWDQIQED----------KKHE 225
Query: 529 KGEKINASTDSLAKDLIV 546
+ EK + L +D+I+
Sbjct: 226 EAEKRKSVDTQLQEDMII 243
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 32.3 bits (72), Expect = 1.9
Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 617 QHLDSQKMDMSNIVLMLIQKLLN---ENPFKCEDP----CEGENKCSEPRASKAASMSNR 669
+H + K D + ++ L++++ N + + C+ P +G PR++ AA ++
Sbjct: 668 RHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSIQKADGTATAPPPRSNHAAEEASS 727
Query: 670 SDKAEEQCQEHQELDCT 686
D+ EE+ Q Q + T
Sbjct: 728 EDEEEEEVQAMQSFNST 744
>gi|111548668 zinc finger protein 676 [Homo sapiens]
Length = 588
Score = 32.0 bits (71), Expect = 2.5
Identities = 43/203 (21%), Positives = 71/203 (34%), Gaps = 28/203 (13%)
Query: 492 SAEKVGEHILKEGLTIWNQKQGNSCKVAT--KACSNKDEKGEKINASTDSLAKDLIVSAL 549
+ K G + L + LT K K A CSN + + K+ + S
Sbjct: 92 NVHKEGYNKLNQSLTTTQSKVFQCGKYANVFHKCSNSNRHKIRHTGEKGLKCKEYVRSFC 151
Query: 550 KLIQYHLTQQTK-----GKDTCEEDCPGSTMGYMAQSTQY------------EKCGGGQS 592
L HL+Q + CEE+ G + + T Y E+CG S
Sbjct: 152 MLS--HLSQHERIYTRENSYKCEEN--GKAFNWSSTLTYYKSIHTGEKPYKCEECGKAFS 207
Query: 593 AKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGE 652
++ K H P C++ + + + + ++ E P+KCE+ +G
Sbjct: 208 KFSILTKHKVIHTGEKPYKCEECGKAFNRSSILTKHKIIHT-----GEKPYKCEECGKGF 262
Query: 653 NKCSEPRASKAASMSNRSDKAEE 675
+ S KA + K EE
Sbjct: 263 SSVSTLNTHKAIHAEEKPYKCEE 285
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 31.6 bits (70), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 47 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 100
VS N+E K Y + S G + S ++ + +KD K+DQ + + + C
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349
Query: 101 KQAPSDPVSVLNWL 114
K P P+++L L
Sbjct: 2350 KMKPR-PIAILQGL 2362
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 31.6 bits (70), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 47 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 100
VS N+E K Y + S G + S ++ + +KD K+DQ + + + C
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349
Query: 101 KQAPSDPVSVLNWL 114
K P P+++L L
Sbjct: 2350 KMKPR-PIAILQGL 2362
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 31.6 bits (70), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 47 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 100
VS N+E K Y + S G + S ++ + +KD K+DQ + + + C
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303
Query: 101 KQAPSDPVSVLNWL 114
K P P+++L L
Sbjct: 2304 KMKPR-PIAILQGL 2316
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 31.6 bits (70), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 47 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 100
VS N+E K Y + S G + S ++ + +KD K+DQ + + + C
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303
Query: 101 KQAPSDPVSVLNWL 114
K P P+++L L
Sbjct: 2304 KMKPR-PIAILQGL 2316
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 31.6 bits (70), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 47 VSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSK------TEGSVCLF 100
VS N+E K Y + S G + S ++ + +KD K+DQ + + + C
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303
Query: 101 KQAPSDPVSVLNWL 114
K P P+++L L
Sbjct: 2304 KMKPR-PIAILQGL 2316
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 31.6 bits (70), Expect = 3.3
Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 29/171 (16%)
Query: 180 TAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEK 239
++++ + + SP+ PA+P SP + S+ S + +S + A +K
Sbjct: 1079 SSSRGSGRHSSPA--PAQPKKES----SPKSQDSVSSPSPQKQKSASALTYTASSTSAKK 1132
Query: 240 LEG----------KSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGT 289
G KS+ HS+ + S R A+ + + + A E RG
Sbjct: 1133 ASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTSKPNSPRVSQARAGEGRGA 1192
Query: 290 GEESREGGQKSF------LYSELSNKSKSGDKQMS-------QRESKEFAD 327
G+ R S + S L SKS DK +S Q+E++ D
Sbjct: 1193 GKHVRSSSMASLRSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKETRRSTD 1243
>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
sapiens]
Length = 1198
Score = 31.2 bits (69), Expect = 4.3
Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%)
Query: 32 EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 91
EG++D+D + D +Y + + + + G E + + + ++
Sbjct: 893 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 941
Query: 92 KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 147
+EGS+ Q P P SD + + A S PS ST K ++G G
Sbjct: 942 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 993
Query: 148 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 199
H S + + AD V D +R + + KN N+SP APPA
Sbjct: 994 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 1053
Query: 200 STQRAVISPDGE 211
P E
Sbjct: 1054 DKMMKSFKPTSE 1065
>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
sapiens]
Length = 519
Score = 31.2 bits (69), Expect = 4.3
Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%)
Query: 32 EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 91
EG++D+D + D +Y + + + + G E + + + ++
Sbjct: 214 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 262
Query: 92 KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 147
+EGS+ Q P P SD + + A S PS ST K ++G G
Sbjct: 263 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 314
Query: 148 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 199
H S + + AD V D +R + + KN N+SP APPA
Sbjct: 315 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 374
Query: 200 STQRAVISPDGE 211
P E
Sbjct: 375 DKMMKSFKPTSE 386
>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
sapiens]
Length = 917
Score = 31.2 bits (69), Expect = 4.3
Identities = 43/192 (22%), Positives = 69/192 (35%), Gaps = 31/192 (16%)
Query: 32 EGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQS 91
EG++D+D + D +Y + + + + G E + + + ++
Sbjct: 612 EGEEDEDE-----------DTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRT 660
Query: 92 KTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALS----PSTSTCKHKVGDTEGEY 147
+EGS+ Q P P SD + + A S PS ST K ++G G
Sbjct: 661 HSEGSLL---QEPRGPC-----FASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSM 712
Query: 148 HRAS---SENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNT-----NNNQSPSAPPAKPP 199
H S + + AD V D +R + + KN N+SP APPA
Sbjct: 713 HHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKA 772
Query: 200 STQRAVISPDGE 211
P E
Sbjct: 773 DKMMKSFKPTSE 784
>gi|209862748 ataxin 3-like [Homo sapiens]
Length = 355
Score = 31.2 bits (69), Expect = 4.3
Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 229 IQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRT----PASKIASEMAYEAVELTAA 284
++++ +E + E + S+ S GN + P+T PAS+ ++ + E
Sbjct: 233 LELSRQETNREDEHLRSTIELSMQGSSGNTSQDLPKTSCVTPASEQPKKIKEDYFEKHQQ 292
Query: 285 EMRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDM 344
E + ++S G S+L+ + S++ + +S D IS+G + Q A D
Sbjct: 293 EQKQQQQQSDLPGHSSYLHERPTTSSRAIESDLS--------DDISEGTV----QAAVDT 340
Query: 345 MVSLM-KTLKV 354
++ +M K LK+
Sbjct: 341 ILEIMRKNLKI 351
>gi|31982909 zinc finger protein 394 [Homo sapiens]
Length = 561
Score = 31.2 bits (69), Expect = 4.3
Identities = 42/190 (22%), Positives = 66/190 (34%), Gaps = 38/190 (20%)
Query: 585 EKCGGGQSAKALSVKQLESHRAPGPSTCQK------ENQHLDSQKMDMSNIVLMLIQKLL 638
++CG S A K +H P TC K +N HL+ + S
Sbjct: 389 QECGKSFSQSAALTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHS----------- 437
Query: 639 NENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEE--QCQEHQELDCTSGMKQANGQF 696
+ FKCE+ C E R K E +C+E C KQ + F
Sbjct: 438 RDKHFKCEE-------CGETCHISNLFRHQRLHKGERPYKCEE-----CEKSFKQRSDLF 485
Query: 697 IDKLVESVMKL--CLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDS 754
+ + K C + K N A L + ++ + KP +C+ G +
Sbjct: 486 KHHRIHTGEKPYGCSVCGKRFNQSATLIK-HQRIHTGEKP----YKCLECGERFRQSTHL 540
Query: 755 LGHEVIVNNQ 764
+ H+ I N+
Sbjct: 541 IRHQRIHQNK 550
>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
[Homo sapiens]
Length = 1585
Score = 31.2 bits (69), Expect = 4.3
Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 35/215 (16%)
Query: 163 VNIDYLMNRPQNLRLEMTAAKNTNNN-----QSPSAPPAKPPSTQRAVISPDGECSIDDL 217
+ ++ L N P+ ++LE A T + +P PPA PP T V + S
Sbjct: 385 LELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSA 444
Query: 218 SFYVNRLSS------LVIQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRTPA---- 267
+ V R+ + KEI+ K+E ++ I S R SP PA
Sbjct: 445 AITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP-VPAQIAI 503
Query: 268 ------------SKIASEMAYEAVELTAAEMRGTGE--ESREGGQKSFLYSELS----NK 309
++ EM +EL A E + ES + + E K
Sbjct: 504 TVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKK 563
Query: 310 SKSGDKQMSQRES-KEFADSISKGLMVYANQVASD 343
K+ ++ + E + A+S+S+G + AN ++D
Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTD 598
>gi|121582460 hypothetical protein LOC79762 [Homo sapiens]
Length = 142
Score = 31.2 bits (69), Expect = 4.3
Identities = 13/40 (32%), Positives = 21/40 (52%)
Query: 713 KYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQ 752
+Y+++ A AE AA P RG R +H +P+ Y+
Sbjct: 40 EYADEAEAAAESGTSAADERGPGTRGARRVHFALLPERYE 79
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 30.8 bits (68), Expect = 5.6
Identities = 54/252 (21%), Positives = 94/252 (37%), Gaps = 37/252 (14%)
Query: 233 HKEIK--EKLEGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTG 290
HK+ K + + K KCL + S + I + + V AE+ +
Sbjct: 1633 HKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASK 1692
Query: 291 EESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMK 350
EE R G QK Q+ Q + +E + + K + + M
Sbjct: 1693 EEKRRGEQK---------------VQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1737
Query: 351 TLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRN 410
L SGK K+ K+ + L++S + ++I+G+ + DFVS + N
Sbjct: 1738 VLFQEESGK-------FKQSAEEFRKK-MEKLMESKVITENDISGIRL---DFVSLQQEN 1786
Query: 411 LFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTM 470
++ ++NA + E +K L L + + + +H KC+ E
Sbjct: 1787 --SRAQENA-KLCETNIKELERQL-----QQYREQMQQGQHMEANHYQKCQKLEDELIAQ 1838
Query: 471 KAEMKERDKGKM 482
K E+ E K KM
Sbjct: 1839 KREV-ENLKQKM 1849
>gi|157909822 pragmin [Homo sapiens]
Length = 1402
Score = 30.8 bits (68), Expect = 5.6
Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 24/180 (13%)
Query: 92 KTEGSVCLFKQAPSDPVS----VLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEY 147
K + F P P S +N SDL+K + G +LSPS V T G
Sbjct: 701 KDRSGIETFSPPPPPPKSRHLLKMNKSSSDLEKVSQGSAESLSPSFRGVH--VSFTTGST 758
Query: 148 HRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAA----KNTNNNQSPSAPPAKPPSTQR 203
+S++ +D L + P N ++ A + + SPS P PP Q+
Sbjct: 759 DSLASDS--RTCSDGGPSSELAHSPTNSGKKLFAPVPFPSGSTEDVSPSGPQQPPPLPQK 816
Query: 204 AVISPDGECSIDDLSFYVN-----RLSSLVIQMAHKEIKEKLEGKSKCLHHSICPSPGNK 258
++S S D F+ +S + ++H E E H S SPGN+
Sbjct: 817 KIVS--RAASSPDGFFWTQGSPKPGTASPKLNLSHSETNVHDES-----HFSYSLSPGNR 869
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,959,204
Number of Sequences: 37866
Number of extensions: 1408860
Number of successful extensions: 4521
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 4451
Number of HSP's gapped (non-prelim): 109
length of query: 854
length of database: 18,247,518
effective HSP length: 111
effective length of query: 743
effective length of database: 14,044,392
effective search space: 10434983256
effective search space used: 10434983256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.