BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo sapiens] (605 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 1288 0.0 gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 1157 0.0 gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 1121 0.0 gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 1065 0.0 gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 986 0.0 gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 86 1e-16 gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 86 1e-16 gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 80 7e-15 gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] 79 1e-14 gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] 79 1e-14 gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] 74 4e-13 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 67 5e-11 gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 59 1e-08 gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 59 1e-08 gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 55 2e-07 gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 55 2e-07 gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 54 5e-07 gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 54 5e-07 gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 52 1e-06 gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 52 2e-06 gi|110431370 espin [Homo sapiens] 42 0.002 gi|156139122 CXXC finger 6 [Homo sapiens] 42 0.002 gi|210032580 SET domain containing 1B [Homo sapiens] 42 0.002 gi|239754911 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006 gi|239749451 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006 gi|239743581 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006 gi|158261990 CXXC finger 5 [Homo sapiens] 40 0.008 gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] 39 0.014 gi|153792074 proline rich 12 [Homo sapiens] 39 0.014 gi|56549696 E1A binding protein p400 [Homo sapiens] 39 0.018 >gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo sapiens] Length = 605 Score = 1288 bits (3333), Expect = 0.0 Identities = 605/605 (100%), Positives = 605/605 (100%) Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP Sbjct: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360 Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT Sbjct: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420 Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL Sbjct: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480 Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE Sbjct: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540 Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP Sbjct: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600 Query: 601 GARKQ 605 GARKQ Sbjct: 601 GARKQ 605 >gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo sapiens] Length = 556 Score = 1157 bits (2993), Expect = 0.0 Identities = 555/605 (91%), Positives = 556/605 (91%), Gaps = 49/605 (8%) Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF--------- 171 Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 +SRGCGVCRGCQTQEDCGHC Sbjct: 172 ----------------------------------------KSRGCGVCRGCQTQEDCGHC 191 Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP Sbjct: 192 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 251 Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP Sbjct: 252 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 311 Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT Sbjct: 312 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 371 Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL Sbjct: 372 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 431 Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE Sbjct: 432 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 491 Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP Sbjct: 492 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 551 Query: 601 GARKQ 605 GARKQ Sbjct: 552 GARKQ 556 >gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo sapiens] Length = 549 Score = 1121 bits (2899), Expect = 0.0 Identities = 544/605 (89%), Positives = 547/605 (90%), Gaps = 56/605 (9%) Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360 TEPHPRALAPSPPAEFIYY C D+ Sbjct: 301 TEPHPRALAPSPPAEFIYY------------------------------------CVDED 324 Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420 + +KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT Sbjct: 325 E--------------------LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 364 Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL Sbjct: 365 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 424 Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE Sbjct: 425 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 484 Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP Sbjct: 485 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 544 Query: 601 GARKQ 605 GARKQ Sbjct: 545 GARKQ 549 >gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo sapiens] Length = 586 Score = 1065 bits (2755), Expect = 0.0 Identities = 517/592 (87%), Positives = 517/592 (87%), Gaps = 69/592 (11%) Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360 TEP QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP Sbjct: 301 TEP-----------------------QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 337 Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT Sbjct: 338 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 397 Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL Sbjct: 398 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 457 Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540 LQ LP VKQ E Sbjct: 458 LQAVD-------PGLPSVKQ---------------------------------------E 471 Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 592 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP Sbjct: 472 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 523 >gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo sapiens] Length = 503 Score = 986 bits (2550), Expect = 0.0 Identities = 492/605 (81%), Positives = 495/605 (81%), Gaps = 102/605 (16%) Query: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT Sbjct: 1 MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60 Query: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT Sbjct: 61 LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120 Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180 Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240 Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360 TEPHPRALAPSPPAEFIYY C D+ Sbjct: 301 TEPHPRALAPSPPAEFIYY------------------------------------CVDED 324 Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420 + +KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT Sbjct: 325 E--------------------LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 364 Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL Sbjct: 365 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 424 Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540 LQ LP VKQ E Sbjct: 425 LQAVD-------PGLPSVKQ---------------------------------------E 438 Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP Sbjct: 439 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 498 Query: 601 GARKQ 605 GARKQ Sbjct: 499 GARKQ 503 >gi|7710145 methyl-CpG binding domain protein 2 testis-specific isoform [Homo sapiens] Length = 302 Score = 85.5 bits (210), Expect = 1e-16 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%) Query: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65 +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+ Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209 Query: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97 G K P + K++ + P K Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234 >gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo sapiens] Length = 411 Score = 85.5 bits (210), Expect = 1e-16 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%) Query: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65 +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+ Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209 Query: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97 G K P + K++ + P K Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234 >gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo sapiens] Length = 3969 Score = 79.7 bits (195), Expect = 7e-15 Identities = 83/297 (27%), Positives = 119/297 (40%), Gaps = 64/297 (21%) Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNR 332 G D K + A+PL PP +P +P R AP P P Sbjct: 1109 GNDDKSSIAGSEDAEPLAPPI-----KPIKPVTRNKAPQEP--------------PVKKG 1149 Query: 333 RQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC--LQFAMKR--LLPS 388 R++R+CG C C DCG C C DKPKFGG N K+Q C+ R+C LQ+ + L Sbjct: 1150 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQ 1209 Query: 389 VWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFV 448 + + S ++ + SS ++ + + KPT + R AP K + Sbjct: 1210 AKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAR-----EDPAPKKSSSE---- 1260 Query: 449 LPPPGTDLVFLREGASSPVQVPGPVA--ASTEALLQEAQCSGLSWVVALPQVKQEKADTQ 506 PPP + + V PGP + A+T A + ++ QV Q Sbjct: 1261 -PPPRKPVE--EKSEEGNVSAPGPESKQATTPASRKSSK-----------QVSQ------ 1300 Query: 507 DEWTPGTAVLTSPVLVPGCPSKAVDPGLPS--VKQEPPDPEEDKEENKDDSASKLAP 561 P + P G P K V PS K++PP PE E++K K+AP Sbjct: 1301 ----PALVIPPQPP-TTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQ---KKVAP 1349 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 30/115 (26%) Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 255 RSR CG C GCQ EDCG C CL P+ G L++Q Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210 Query: 256 KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPR 306 K V+++ + K + +K +S + +Q P P + P P +EP PR Sbjct: 1211 KAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK-PTPSAREDPAPKKSSSEPPPR 1264 >gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] Length = 660 Score = 79.0 bits (193), Expect = 1e-14 Identities = 60/195 (30%), Positives = 77/195 (39%), Gaps = 49/195 (25%) Query: 253 RQWKCVQRRC----------LRGKHARRKGGCDSKMAARRRPGA---QPLPPPP------ 293 R+W C R C R K +R + G + + R G +P+P P Sbjct: 66 REWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAG 123 Query: 294 -----------PSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACA 342 S SP + P P PS + Q +R R CG C Sbjct: 124 SGTGVGAMLARGSASPHKSSPQPLVATPS----------QHHQQQQQQIKRSARMCGECE 173 Query: 343 ACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESED 395 AC R DCG CDFC D KFGG N+ RQKCR RQC ++ L P SES Sbjct: 174 ACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLP 233 Query: 396 GAGSPPPYRRRKRPS 410 P P +++ +PS Sbjct: 234 RPRRPLPTQQQPQPS 248 Score = 46.2 bits (108), Expect = 9e-05 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%) Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272 +I +R CG C C+ EDCGHC C + P RQ KC R+C LR + + + Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219 Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302 +P P P Q P+P++ Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249 Score = 41.2 bits (95), Expect = 0.003 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215 ++Q+ KR CGEC AC+ TEDCG C C + + KC R+C Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208 >gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] Length = 656 Score = 79.0 bits (193), Expect = 1e-14 Identities = 60/195 (30%), Positives = 77/195 (39%), Gaps = 49/195 (25%) Query: 253 RQWKCVQRRC----------LRGKHARRKGGCDSKMAARRRPGA---QPLPPPP------ 293 R+W C R C R K +R + G + + R G +P+P P Sbjct: 66 REWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAG 123 Query: 294 -----------PSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACA 342 S SP + P P PS + Q +R R CG C Sbjct: 124 SGTGVGAMLARGSASPHKSSPQPLVATPS----------QHHQQQQQQIKRSARMCGECE 173 Query: 343 ACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESED 395 AC R DCG CDFC D KFGG N+ RQKCR RQC ++ L P SES Sbjct: 174 ACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLP 233 Query: 396 GAGSPPPYRRRKRPS 410 P P +++ +PS Sbjct: 234 RPRRPLPTQQQPQPS 248 Score = 46.2 bits (108), Expect = 9e-05 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%) Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272 +I +R CG C C+ EDCGHC C + P RQ KC R+C LR + + + Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219 Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302 +P P P Q P+P++ Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249 Score = 41.2 bits (95), Expect = 0.003 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215 ++Q+ KR CGEC AC+ TEDCG C C + + KC R+C Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208 >gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] Length = 291 Score = 73.9 bits (180), Expect = 4e-13 Identities = 32/61 (52%), Positives = 43/61 (70%) Query: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQ 66 +CPAL GW+R EV R+SG + G D +Y SP+G + RSK +L RYLG + DL+ FDF+ Sbjct: 7 ECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRT 66 Query: 67 G 67 G Sbjct: 67 G 67 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/109 (36%), Positives = 50/109 (45%), Gaps = 17/109 (15%) Query: 337 KCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQF--------------AM 382 +CG C CLR DCG C C DKPKFGG N K+Q C +R+C + + Sbjct: 965 RCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIV 1024 Query: 383 KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRH---HLGPTLKPTLATR 428 K LLP ES + + PP RR R H GP + +L R Sbjct: 1025 KTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQR 1073 Score = 50.4 bits (119), Expect = 5e-06 Identities = 40/124 (32%), Positives = 54/124 (43%), Gaps = 12/124 (9%) Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRCLRGKHARRKGGCDSK 277 R CG CRGC +DCG C CL P+ P ++Q CV R+C K RK + Sbjct: 962 RMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQC-CVYRKC--DKIEARK---MER 1015 Query: 278 MAARRRPGAQPLPPPPPSQSPE--PTEPHP-RALAPSPPAEFIYYCVDEDELQPYTNRRQ 334 +A + R + L P +SPE P P P R P E + +E R+ Sbjct: 1016 LAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKS 1075 Query: 335 NRKC 338 R+C Sbjct: 1076 ARRC 1079 Score = 32.0 bits (71), Expect = 1.7 Identities = 10/20 (50%), Positives = 12/20 (60%) Query: 176 CGECAACQVTEDCGACSTCL 195 CG C C +DCG+C CL Sbjct: 966 CGHCRGCLRVQDCGSCVNCL 985 Score = 30.8 bits (68), Expect = 3.8 Identities = 13/30 (43%), Positives = 13/30 (43%) Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPP 313 P P P PPP P T P P P PP Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPP 434 Score = 30.4 bits (67), Expect = 4.9 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 3/51 (5%) Query: 265 GKHARRKGGCDSKMAARRRPGAQPLPPP--PPSQSPEPTEPHPRALAPSPP 313 G+ + + M A + A+ PPP PP+ SP P P P + +P PP Sbjct: 378 GEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP-STSPPPP 427 Score = 29.6 bits (65), Expect = 8.4 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 10/42 (23%) Query: 284 PGAQPLPP-PPPSQSPEP---------TEPHPRALAPSPPAE 315 P P PP PPPS SP P P P P PPA+ Sbjct: 409 PAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450 >gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo sapiens] Length = 1632 Score = 58.9 bits (141), Expect = 1e-08 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%) Query: 321 VDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQF 380 +++D+ + N + R+CG C C ++ +CG+C C D KFGGS + +Q C+ R+C Sbjct: 652 IEKDDREDKENAFKRRRCGVCEVC-QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNM 710 Query: 381 AMK 383 AMK Sbjct: 711 AMK 713 Score = 35.0 bits (79), Expect = 0.20 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 167 EQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215 ++ FKR CG C CQ E CG C C + + C+ RRC Sbjct: 660 KENAFKRRRCGVCEVCQQPE-CGKCKACKDMVKFGGSGRSKQACQERRC 707 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG--LRRQWKCVQRRC 262 + R CGVC CQ Q +CG C C + G R + C +RRC Sbjct: 665 KRRRCGVCEVCQ-QPECGKCKACKDMVKFGGSGRSKQACQERRC 707 >gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo sapiens] Length = 1616 Score = 58.9 bits (141), Expect = 1e-08 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%) Query: 321 VDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQF 380 +++D+ + N + R+CG C C ++ +CG+C C D KFGGS + +Q C+ R+C Sbjct: 636 IEKDDREDKENAFKRRRCGVCEVC-QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNM 694 Query: 381 AMK 383 AMK Sbjct: 695 AMK 697 Score = 35.0 bits (79), Expect = 0.20 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 167 EQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215 ++ FKR CG C CQ E CG C C + + C+ RRC Sbjct: 644 KENAFKRRRCGVCEVCQQPE-CGKCKACKDMVKFGGSGRSKQACQERRC 691 Score = 33.9 bits (76), Expect = 0.44 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG--LRRQWKCVQRRC 262 + R CGVC CQ Q +CG C C + G R + C +RRC Sbjct: 649 KRRRCGVCEVCQ-QPECGKCKACKDMVKFGGSGRSKQACQERRC 691 >gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo sapiens] Length = 1336 Score = 55.1 bits (131), Expect = 2e-07 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%) Query: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378 RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+ Sbjct: 607 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 652 >gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo sapiens] Length = 1265 Score = 55.1 bits (131), Expect = 2e-07 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%) Query: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378 RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+ Sbjct: 576 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 621 >gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] Length = 498 Score = 53.5 bits (127), Expect = 5e-07 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%) Query: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62 D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F Sbjct: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167 Query: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115 DF P+ + KK K P P R R SG R +A E Sbjct: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217 >gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] Length = 486 Score = 53.5 bits (127), Expect = 5e-07 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%) Query: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62 D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F Sbjct: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155 Query: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115 DF P+ + KK K P P R R SG R +A E Sbjct: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205 >gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapiens] Length = 694 Score = 52.4 bits (124), Expect = 1e-06 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 1/46 (2%) Query: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC 377 RR+ +C C AC+R +CG C FC D KFGG + +Q C RQC Sbjct: 33 RRRRTRCRRCRACVRT-ECGDCHFCRDMKKFGGPGRMKQSCLLRQC 77 Score = 41.6 bits (96), Expect = 0.002 Identities = 53/207 (25%), Positives = 71/207 (34%), Gaps = 50/207 (24%) Query: 139 SFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACS----TC 194 S G G +R +T C+ CRA R CG+C C+ + G +C Sbjct: 24 SSRGPGAGARRRRTRCRRCRA-----------CVRTECGDCHFCRDMKKFGGPGRMKQSC 72 Query: 195 LLQ------LPHDVASGLFCKCERRRCLRIVERSRG-----CGVCR-----GCQTQ---- 234 LL+ LPH L + + + E G C +C GC Sbjct: 73 LLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLKMGKAE 132 Query: 235 -------EDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQ 287 +C CP C + R +RR G+ G S P Sbjct: 133 GVINAEIPNCWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLG---SGWKLTEEP--- 186 Query: 288 PLPPPPP-SQSPEPTEPHPRALAPSPP 313 PLPPPPP + P P P P + P PP Sbjct: 187 PLPPPPPRRKGPLPAGPPPEDV-PGPP 212 >gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] Length = 1162 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 14/90 (15%) Query: 291 PPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTN--RRQNRKCGACAACLRRM 348 P P P +P PR L P PA P + RR+ +C C AC++ Sbjct: 533 PTIPITKPHTMKPAPR-LTPVRPAA----------ASPIVSGARRRRVRCRKCKACVQG- 580 Query: 349 DCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378 +CG C +C D KFGG + +Q C RQCL Sbjct: 581 ECGVCHYCRDMKKFGGPGRMKQSCVLRQCL 610 >gi|110431370 espin [Homo sapiens] Length = 854 Score = 42.0 bits (97), Expect = 0.002 Identities = 67/288 (23%), Positives = 98/288 (34%), Gaps = 44/288 (15%) Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAA 343 P P PPPP +Q P P +P P P Y +++L+ ++ +C Sbjct: 435 PSFPPPPPPPGTQLPPPPPGYPAPKPPVGPQAADIYMQTKNKLRHVETEALKKELSSCDG 494 Query: 344 --CLRRMDCGRCDFCCDK-PKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSP 400 LRR D R K P G ++ +C P + G Sbjct: 495 HDGLRRQDSSRKPRAFSKQPSTGDYYRQLGRC--------------PGETLAARPGMAHS 540 Query: 401 PPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGG--------GFVLPPP 452 R R +P+ A LGP + +L +A P P G + PPP Sbjct: 541 EEVRAR-QPARAGCPRLGPAARGSLEGPSAPPQAALLPGNHVPNGCAADPKASRELPPPP 599 Query: 453 GTDLVFLREGASSPVQVPG-PVAASTEALLQEAQCSGL----SWVVALPQ------VKQE 501 L E ASSP P P+ ++ Q S S+ + P + + Sbjct: 600 PPPPPPLPEAASSPPPAPPLPLESAGPGCGQRRSSSSTGSTKSFNMMSPTGDNSELLAEI 659 Query: 502 KADTQDEWTPGTAVLTS-------PVLVPGCPSKAVDPGLPSVKQEPP 542 KA + TP + LT+ P P P +V P L V+ P Sbjct: 660 KAGKSLKPTPQSKGLTTVFSGIGQPAFQPDSPLPSVSPALSPVRSPTP 707 Score = 30.4 bits (67), Expect = 4.9 Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 6/51 (11%) Query: 259 QRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPP----SQSPEPTEPHP 305 Q L G H GC + A R P PPPPP + SP P P P Sbjct: 572 QAALLPGNHV--PNGCAADPKASRELPPPPPPPPPPLPEAASSPPPAPPLP 620 >gi|156139122 CXXC finger 6 [Homo sapiens] Length = 2136 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 9/82 (10%) Query: 326 LQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRL 385 L P +++ ++CG C C ++ +CG C +C ++ Q C+ R+C + K Sbjct: 579 LLPTLEKKKRKRCGVCEPCQQKTNCGECTYCKNR------KNSHQICKKRKCEELKKK-- 630 Query: 386 LPSVWSESEDGAGSPPPYRRRK 407 PSV E + P R +K Sbjct: 631 -PSVVVPLEVIKENKRPQREKK 651 Score = 32.7 bits (73), Expect = 0.99 Identities = 10/24 (41%), Positives = 15/24 (62%) Query: 220 ERSRGCGVCRGCQTQEDCGHCPIC 243 ++ + CGVC CQ + +CG C C Sbjct: 586 KKRKRCGVCEPCQQKTNCGECTYC 609 Score = 31.6 bits (70), Expect = 2.2 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 8/45 (17%) Query: 172 KRVGCGECAACQVTEDCGACSTCL-LQLPHDVASGLFCKCERRRC 215 KR CG C CQ +CG C+ C + H + C++R+C Sbjct: 587 KRKRCGVCEPCQQKTNCGECTYCKNRKNSHQI-------CKKRKC 624 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 41.6 bits (96), Expect = 0.002 Identities = 17/30 (56%), Positives = 18/30 (60%) Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPP 313 PG PLPPPPP P+P P P L P PP Sbjct: 685 PGFPPLPPPPPPPPPQPGFPMPPPLPPPPP 714 Score = 33.1 bits (74), Expect = 0.76 Identities = 12/26 (46%), Positives = 13/26 (50%) Query: 288 PLPPPPPSQSPEPTEPHPRALAPSPP 313 P+PPP P P P HP P PP Sbjct: 704 PMPPPLPPPPPPPPPAHPAVTVPPPP 729 Score = 32.0 bits (71), Expect = 1.7 Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 16/160 (10%) Query: 391 SESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLP 450 + S+ G P P RPSS + PT P + + D P G P Sbjct: 548 TNSQPGFRGPTP--PSSRPSSTGLEDISPTPLPD-SDEDEELDLGLGPRPPPEPG----P 600 Query: 451 PPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVA---LPQVKQEKADTQD 507 P L L + A + + G ++E + + Q SG ++ +P AD Sbjct: 601 PDPAGL--LSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPK 658 Query: 508 EW--TPGTAVLTSP-VLVPGCPSKAVDPGLPSVKQEPPDP 544 TPG A + +P VL P P PG P + PP P Sbjct: 659 PMVVTPGAAAVAAPSVLAPTLPLPP-PPGFPPLPPPPPPP 697 Score = 30.0 bits (66), Expect = 6.4 Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 2/28 (7%) Query: 288 PLPPPP--PSQSPEPTEPHPRALAPSPP 313 PLPPPP P P P P P+ P PP Sbjct: 680 PLPPPPGFPPLPPPPPPPPPQPGFPMPP 707 >gi|239754911 PREDICTED: hypothetical protein [Homo sapiens] Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 14/114 (12%) Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPR----PGLRRQWKCVQRRCLRG 265 C R + R + G C C CP PPR P L +R C Sbjct: 109 CHHRPRYHLRRRPQPHGAASSCSLPR-CRLCPERSAPPRRRGPPPLPTSCHWARRSC--- 164 Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPRALAPSPPAE 315 A R+GG S P A P P PP SP P P P A + PP + Sbjct: 165 --ALRRGGAASWRRGPGTPAAAPEAPSPPDHSPSPWTSRCPPCPHASSFLPPGQ 216 >gi|239749451 PREDICTED: hypothetical protein [Homo sapiens] Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 14/114 (12%) Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPR----PGLRRQWKCVQRRCLRG 265 C R + R + G C C CP PPR P L +R C Sbjct: 109 CHHRPRYHLRRRPQPHGAASSCSLPR-CRLCPERSAPPRRRGPPPLPTSCHWARRSC--- 164 Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPRALAPSPPAE 315 A R+GG S P A P P PP SP P P P A + PP + Sbjct: 165 --ALRRGGAASWRRGPGTPAAAPEAPSPPDHSPSPWTSRCPPCPHASSFLPPGQ 216 >gi|239743581 PREDICTED: hypothetical protein [Homo sapiens] Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 14/114 (12%) Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPR----PGLRRQWKCVQRRCLRG 265 C R + R + G C C CP PPR P L +R C Sbjct: 109 CHHRPRYHLRRRPQPHGAASSCSLPR-CRLCPERSAPPRRRGPPPLPTSCHWARRSC--- 164 Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPRALAPSPPAE 315 A R+GG S P A P P PP SP P P P A + PP + Sbjct: 165 --ALRRGGAASWRRGPGTPAAAPEAPSPPDHSPSPWTSRCPPCPHASSFLPPGQ 216 >gi|158261990 CXXC finger 5 [Homo sapiens] Length = 322 Score = 39.7 bits (91), Expect = 0.008 Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 6/54 (11%) Query: 330 TNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 383 + +++ ++CG CA C RR++C +C C ++ K G Q C++R+C + K Sbjct: 255 SGKKKRKRCGMCAPCRRRINCEQCSSCRNR-KTG-----HQICKFRKCEELKKK 302 Score = 30.0 bits (66), Expect = 6.4 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 172 KRVGCGECAACQVTEDCGACSTCL-LQLPHDVASGLFCKCE 211 KR CG CA C+ +C CS+C + H + F KCE Sbjct: 259 KRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICK--FRKCE 297 >gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] Length = 580 Score = 38.9 bits (89), Expect = 0.014 Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%) Query: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65 GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K Sbjct: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148 Query: 66 QGI 68 +GI Sbjct: 149 RGI 151 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 38.9 bits (89), Expect = 0.014 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAP--SPPAEFIYYCVDEDELQPYTNRRQNRKCGAC 341 P PLPPPPP P P P P A AP +PP E ++ EL +K Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555 Query: 342 AAC 344 A C Sbjct: 1556 AVC 1558 Score = 34.7 bits (78), Expect = 0.26 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 284 PGAQP-LPPPPPSQSPEPTEPHPRALAPSPP 313 P QP LP PPP +P P+ P P L P PP Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPP 1506 Score = 33.9 bits (76), Expect = 0.44 Identities = 16/51 (31%), Positives = 19/51 (37%) Query: 263 LRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPP 313 L G + G +P P P P P P P P P+ PSPP Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP 1486 Score = 30.0 bits (66), Expect = 6.4 Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 10/79 (12%) Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300 P+ L PP P L V + K G A R QP PPPPP P P Sbjct: 791 PLVLPPPPPQLLPS---VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847 Query: 301 --TEPHPRA-----LAPSP 312 E H R+ APSP Sbjct: 848 LQLEAHLRSHGLEPAAPSP 866 >gi|56549696 E1A binding protein p400 [Homo sapiens] Length = 3122 Score = 38.5 bits (88), Expect = 0.018 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 279 AARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPA 314 A + P QP PPPPP Q P P P P+A PPA Sbjct: 2502 AVAQPPPPQPQPPPPP-QQPPPPLPQPQAAGSQPPA 2536 Score = 30.0 bits (66), Expect = 6.4 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Query: 454 TDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGT 513 T + +++ AS+ Q A T+A Q + V A QV Q+K Q T + Sbjct: 3018 TPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTAS 3077 Query: 514 AVLTSPVLVPGCPSKAVDPGLPSVKQEPP 542 A P+ PG P+ A P + P Sbjct: 3078 A----PLQTPGAPNPAQVPASSDSPSQQP 3102 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.443 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,237,876 Number of Sequences: 37866 Number of extensions: 2054551 Number of successful extensions: 23977 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 266 Number of HSP's successfully gapped in prelim test: 362 Number of HSP's that attempted gapping in prelim test: 18123 Number of HSP's gapped (non-prelim): 5044 length of query: 605 length of database: 18,247,518 effective HSP length: 108 effective length of query: 497 effective length of database: 14,157,990 effective search space: 7036521030 effective search space used: 7036521030 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.