Guide to the Human Genome
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Search of human proteins with 21464117

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
         (605 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ...  1288   0.0  
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho...  1157   0.0  
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo...  1121   0.0  
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ...  1065   0.0  
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s...   986   0.0  
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i...    86   1e-16
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s...    86   1e-16
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    80   7e-15
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       79   1e-14
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       79   1e-14
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]          74   4e-13
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    67   5e-11
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    59   1e-08
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    59   1e-08
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    55   2e-07
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [...    55   2e-07
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]     54   5e-07
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]       54   5e-07
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    52   1e-06
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]    52   2e-06
gi|110431370 espin [Homo sapiens]                                      42   0.002
gi|156139122 CXXC finger 6 [Homo sapiens]                              42   0.002
gi|210032580 SET domain containing 1B [Homo sapiens]                   42   0.002
gi|239754911 PREDICTED: hypothetical protein [Homo sapiens]            40   0.006
gi|239749451 PREDICTED: hypothetical protein [Homo sapiens]            40   0.006
gi|239743581 PREDICTED: hypothetical protein [Homo sapiens]            40   0.006
gi|158261990 CXXC finger 5 [Homo sapiens]                              40   0.008
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]          39   0.014
gi|153792074 proline rich 12 [Homo sapiens]                            39   0.014
gi|56549696 E1A binding protein p400 [Homo sapiens]                    39   0.018

>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
           sapiens]
          Length = 605

 Score = 1288 bits (3333), Expect = 0.0
 Identities = 605/605 (100%), Positives = 605/605 (100%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360
           TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP
Sbjct: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360

Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420
           KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420

Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480

Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540
           LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE
Sbjct: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540

Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP
Sbjct: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600

Query: 601 GARKQ 605
           GARKQ
Sbjct: 601 GARKQ 605


>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
           sapiens]
          Length = 556

 Score = 1157 bits (2993), Expect = 0.0
 Identities = 555/605 (91%), Positives = 556/605 (91%), Gaps = 49/605 (8%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF         
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF--------- 171

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
                                                   +SRGCGVCRGCQTQEDCGHC
Sbjct: 172 ----------------------------------------KSRGCGVCRGCQTQEDCGHC 191

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 192 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 251

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360
           TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP
Sbjct: 252 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 311

Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420
           KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 312 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 371

Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 372 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 431

Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540
           LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE
Sbjct: 432 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 491

Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP
Sbjct: 492 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 551

Query: 601 GARKQ 605
           GARKQ
Sbjct: 552 GARKQ 556


>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
           sapiens]
          Length = 549

 Score = 1121 bits (2899), Expect = 0.0
 Identities = 544/605 (89%), Positives = 547/605 (90%), Gaps = 56/605 (9%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360
           TEPHPRALAPSPPAEFIYY                                    C D+ 
Sbjct: 301 TEPHPRALAPSPPAEFIYY------------------------------------CVDED 324

Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420
           +                    +KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 325 E--------------------LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 364

Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 365 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 424

Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540
           LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE
Sbjct: 425 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 484

Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP
Sbjct: 485 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 544

Query: 601 GARKQ 605
           GARKQ
Sbjct: 545 GARKQ 549


>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
           sapiens]
          Length = 586

 Score = 1065 bits (2755), Expect = 0.0
 Identities = 517/592 (87%), Positives = 517/592 (87%), Gaps = 69/592 (11%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360
           TEP                       QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP
Sbjct: 301 TEP-----------------------QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 337

Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420
           KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 338 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 397

Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 398 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 457

Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540
           LQ            LP VKQ                                       E
Sbjct: 458 LQAVD-------PGLPSVKQ---------------------------------------E 471

Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 592
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP
Sbjct: 472 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 523


>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
           sapiens]
          Length = 503

 Score =  986 bits (2550), Expect = 0.0
 Identities = 492/605 (81%), Positives = 495/605 (81%), Gaps = 102/605 (16%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360
           TEPHPRALAPSPPAEFIYY                                    C D+ 
Sbjct: 301 TEPHPRALAPSPPAEFIYY------------------------------------CVDED 324

Query: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420
           +                    +KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 325 E--------------------LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 364

Query: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 365 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 424

Query: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540
           LQ            LP VKQ                                       E
Sbjct: 425 LQAVD-------PGLPSVKQ---------------------------------------E 438

Query: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP
Sbjct: 439 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 498

Query: 601 GARKQ 605
           GARKQ
Sbjct: 499 GARKQ 503


>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
           isoform [Homo sapiens]
          Length = 302

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209

Query: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
            G       K  P  +   K++  + P    K
Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234


>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
           sapiens]
          Length = 411

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209

Query: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
            G       K  P  +   K++  + P    K
Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 83/297 (27%), Positives = 119/297 (40%), Gaps = 64/297 (21%)

Query: 273  GCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNR 332
            G D K +      A+PL PP      +P +P  R  AP  P              P    
Sbjct: 1109 GNDDKSSIAGSEDAEPLAPPI-----KPIKPVTRNKAPQEP--------------PVKKG 1149

Query: 333  RQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC--LQFAMKR--LLPS 388
            R++R+CG C  C    DCG C  C DKPKFGG N K+Q C+ R+C  LQ+   +  L   
Sbjct: 1150 RRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQ 1209

Query: 389  VWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFV 448
              +  +    S    ++  + SS  ++ +  + KPT + R        AP K  +     
Sbjct: 1210 AKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAR-----EDPAPKKSSSE---- 1260

Query: 449  LPPPGTDLVFLREGASSPVQVPGPVA--ASTEALLQEAQCSGLSWVVALPQVKQEKADTQ 506
             PPP   +    +     V  PGP +  A+T A  + ++           QV Q      
Sbjct: 1261 -PPPRKPVE--EKSEEGNVSAPGPESKQATTPASRKSSK-----------QVSQ------ 1300

Query: 507  DEWTPGTAVLTSPVLVPGCPSKAVDPGLPS--VKQEPPDPEEDKEENKDDSASKLAP 561
                P   +   P    G P K V    PS   K++PP PE   E++K     K+AP
Sbjct: 1301 ----PALVIPPQPP-TTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQ---KKVAP 1349



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 30/115 (26%)

Query: 221  RSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 255
            RSR CG C GCQ  EDCG C  CL  P+ G                         L++Q 
Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210

Query: 256  KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPR 306
            K V+++  + K + +K   +S +       +Q  P P   + P P    +EP PR
Sbjct: 1211 KAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK-PTPSAREDPAPKKSSSEPPPR 1264


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 60/195 (30%), Positives = 77/195 (39%), Gaps = 49/195 (25%)

Query: 253 RQWKCVQRRC----------LRGKHARRKGGCDSKMAARRRPGA---QPLPPPP------ 293
           R+W C  R C           R K +R + G +   +  R  G    +P+P P       
Sbjct: 66  REWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAG 123

Query: 294 -----------PSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACA 342
                       S SP  + P P    PS             + Q    +R  R CG C 
Sbjct: 124 SGTGVGAMLARGSASPHKSSPQPLVATPS----------QHHQQQQQQIKRSARMCGECE 173

Query: 343 ACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESED 395
           AC R  DCG CDFC D  KFGG N+ RQKCR RQC        ++    L P   SES  
Sbjct: 174 ACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLP 233

Query: 396 GAGSPPPYRRRKRPS 410
               P P +++ +PS
Sbjct: 234 RPRRPLPTQQQPQPS 248



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272
           +I   +R CG C  C+  EDCGHC  C    +   P   RQ KC  R+C LR + + +  
Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219

Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302
                         +P  P P  Q P+P++
Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
           ++Q+  KR    CGEC AC+ TEDCG C  C         + +  KC  R+C
Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 60/195 (30%), Positives = 77/195 (39%), Gaps = 49/195 (25%)

Query: 253 RQWKCVQRRC----------LRGKHARRKGGCDSKMAARRRPGA---QPLPPPP------ 293
           R+W C  R C           R K +R + G +   +  R  G    +P+P P       
Sbjct: 66  REWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAG 123

Query: 294 -----------PSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACA 342
                       S SP  + P P    PS             + Q    +R  R CG C 
Sbjct: 124 SGTGVGAMLARGSASPHKSSPQPLVATPS----------QHHQQQQQQIKRSARMCGECE 173

Query: 343 ACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC-------LQFAMKRLLPSVWSESED 395
           AC R  DCG CDFC D  KFGG N+ RQKCR RQC        ++    L P   SES  
Sbjct: 174 ACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLP 233

Query: 396 GAGSPPPYRRRKRPS 410
               P P +++ +PS
Sbjct: 234 RPRRPLPTQQQPQPS 248



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272
           +I   +R CG C  C+  EDCGHC  C    +   P   RQ KC  R+C LR + + +  
Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219

Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302
                         +P  P P  Q P+P++
Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
           ++Q+  KR    CGEC AC+ TEDCG C  C         + +  KC  R+C
Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208


>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
          Length = 291

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 32/61 (52%), Positives = 43/61 (70%)

Query: 7  DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQ 66
          +CPAL  GW+R EV R+SG + G  D +Y SP+G + RSK +L RYLG + DL+ FDF+ 
Sbjct: 7  ECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRT 66

Query: 67 G 67
          G
Sbjct: 67 G 67


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 40/109 (36%), Positives = 50/109 (45%), Gaps = 17/109 (15%)

Query: 337  KCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQF--------------AM 382
            +CG C  CLR  DCG C  C DKPKFGG N K+Q C +R+C +                +
Sbjct: 965  RCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIV 1024

Query: 383  KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRH---HLGPTLKPTLATR 428
            K LLP    ES + +  PP  RR       R     H GP  + +L  R
Sbjct: 1025 KTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQR 1073



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 40/124 (32%), Positives = 54/124 (43%), Gaps = 12/124 (9%)

Query: 221  RSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRCLRGKHARRKGGCDSK 277
            R   CG CRGC   +DCG C  CL  P+   P  ++Q  CV R+C   K   RK     +
Sbjct: 962  RMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQC-CVYRKC--DKIEARK---MER 1015

Query: 278  MAARRRPGAQPLPPPPPSQSPE--PTEPHP-RALAPSPPAEFIYYCVDEDELQPYTNRRQ 334
            +A + R   + L P    +SPE  P  P P R      P E +      +E      R+ 
Sbjct: 1016 LAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKS 1075

Query: 335  NRKC 338
             R+C
Sbjct: 1076 ARRC 1079



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 10/20 (50%), Positives = 12/20 (60%)

Query: 176 CGECAACQVTEDCGACSTCL 195
           CG C  C   +DCG+C  CL
Sbjct: 966 CGHCRGCLRVQDCGSCVNCL 985



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 13/30 (43%), Positives = 13/30 (43%)

Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPP 313
           P   P P PPP   P  T P P    P PP
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPP 434



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 3/51 (5%)

Query: 265 GKHARRKGGCDSKMAARRRPGAQPLPPP--PPSQSPEPTEPHPRALAPSPP 313
           G+    +   +  M A  +  A+  PPP  PP+ SP P  P P + +P PP
Sbjct: 378 GEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP-STSPPPP 427



 Score = 29.6 bits (65), Expect = 8.4
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 10/42 (23%)

Query: 284 PGAQPLPP-PPPSQSPEP---------TEPHPRALAPSPPAE 315
           P   P PP PPPS SP P           P P    P PPA+
Sbjct: 409 PAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQ 450


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 1632

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%)

Query: 321 VDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQF 380
           +++D+ +   N  + R+CG C  C ++ +CG+C  C D  KFGGS + +Q C+ R+C   
Sbjct: 652 IEKDDREDKENAFKRRRCGVCEVC-QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNM 710

Query: 381 AMK 383
           AMK
Sbjct: 711 AMK 713



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%)

Query: 167 EQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
           ++  FKR  CG C  CQ  E CG C  C   +    +      C+ RRC
Sbjct: 660 KENAFKRRRCGVCEVCQQPE-CGKCKACKDMVKFGGSGRSKQACQERRC 707



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG--LRRQWKCVQRRC 262
           + R CGVC  CQ Q +CG C  C    + G   R +  C +RRC
Sbjct: 665 KRRRCGVCEVCQ-QPECGKCKACKDMVKFGGSGRSKQACQERRC 707


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 1616

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%)

Query: 321 VDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQF 380
           +++D+ +   N  + R+CG C  C ++ +CG+C  C D  KFGGS + +Q C+ R+C   
Sbjct: 636 IEKDDREDKENAFKRRRCGVCEVC-QQPECGKCKACKDMVKFGGSGRSKQACQERRCPNM 694

Query: 381 AMK 383
           AMK
Sbjct: 695 AMK 697



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%)

Query: 167 EQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
           ++  FKR  CG C  CQ  E CG C  C   +    +      C+ RRC
Sbjct: 644 KENAFKRRRCGVCEVCQQPE-CGKCKACKDMVKFGGSGRSKQACQERRC 691



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 221 RSRGCGVCRGCQTQEDCGHCPICLRPPRPG--LRRQWKCVQRRC 262
           + R CGVC  CQ Q +CG C  C    + G   R +  C +RRC
Sbjct: 649 KRRRCGVCEVCQ-QPECGKCKACKDMVKFGGSGRSKQACQERRC 691


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
           [Homo sapiens]
          Length = 1336

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)

Query: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378
           RR+  +C  C ACLR  +CG C FC D  KFGG  + +Q C  RQC+
Sbjct: 607 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 652


>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b
           [Homo sapiens]
          Length = 1265

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)

Query: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378
           RR+  +C  C ACLR  +CG C FC D  KFGG  + +Q C  RQC+
Sbjct: 576 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 621


>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
          Length = 498

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 7   DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
           D P L  GW R+   RKSG + G+ D Y  +P G   RSKVEL  Y     D +L    F
Sbjct: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167

Query: 63  DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
           DF       P+ +        KK K P  P   R R     SG  R +A   E
Sbjct: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217


>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
          Length = 486

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 7   DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
           D P L  GW R+   RKSG + G+ D Y  +P G   RSKVEL  Y     D +L    F
Sbjct: 96  DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155

Query: 63  DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
           DF       P+ +        KK K P  P   R R     SG  R +A   E
Sbjct: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 1/46 (2%)

Query: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC 377
           RR+  +C  C AC+R  +CG C FC D  KFGG  + +Q C  RQC
Sbjct: 33  RRRRTRCRRCRACVRT-ECGDCHFCRDMKKFGGPGRMKQSCLLRQC 77



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 53/207 (25%), Positives = 71/207 (34%), Gaps = 50/207 (24%)

Query: 139 SFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACS----TC 194
           S  G G   +R +T C+ CRA             R  CG+C  C+  +  G       +C
Sbjct: 24  SSRGPGAGARRRRTRCRRCRA-----------CVRTECGDCHFCRDMKKFGGPGRMKQSC 72

Query: 195 LLQ------LPHDVASGLFCKCERRRCLRIVERSRG-----CGVCR-----GCQTQ---- 234
           LL+      LPH     L  +  +   +   E   G     C +C      GC       
Sbjct: 73  LLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLKMGKAE 132

Query: 235 -------EDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQ 287
                   +C  CP C +  R          +RR   G+     G   S       P   
Sbjct: 133 GVINAEIPNCWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLG---SGWKLTEEP--- 186

Query: 288 PLPPPPP-SQSPEPTEPHPRALAPSPP 313
           PLPPPPP  + P P  P P  + P PP
Sbjct: 187 PLPPPPPRRKGPLPAGPPPEDV-PGPP 212


>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
          Length = 1162

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 14/90 (15%)

Query: 291 PPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTN--RRQNRKCGACAACLRRM 348
           P  P   P   +P PR L P  PA             P  +  RR+  +C  C AC++  
Sbjct: 533 PTIPITKPHTMKPAPR-LTPVRPAA----------ASPIVSGARRRRVRCRKCKACVQG- 580

Query: 349 DCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378
           +CG C +C D  KFGG  + +Q C  RQCL
Sbjct: 581 ECGVCHYCRDMKKFGGPGRMKQSCVLRQCL 610


>gi|110431370 espin [Homo sapiens]
          Length = 854

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 67/288 (23%), Positives = 98/288 (34%), Gaps = 44/288 (15%)

Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAA 343
           P   P PPPP +Q P P   +P    P  P     Y   +++L+        ++  +C  
Sbjct: 435 PSFPPPPPPPGTQLPPPPPGYPAPKPPVGPQAADIYMQTKNKLRHVETEALKKELSSCDG 494

Query: 344 --CLRRMDCGRCDFCCDK-PKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSP 400
              LRR D  R      K P  G   ++  +C              P     +  G    
Sbjct: 495 HDGLRRQDSSRKPRAFSKQPSTGDYYRQLGRC--------------PGETLAARPGMAHS 540

Query: 401 PPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGG--------GFVLPPP 452
              R R +P+ A    LGP  + +L   +A P     P      G          + PPP
Sbjct: 541 EEVRAR-QPARAGCPRLGPAARGSLEGPSAPPQAALLPGNHVPNGCAADPKASRELPPPP 599

Query: 453 GTDLVFLREGASSPVQVPG-PVAASTEALLQEAQCSGL----SWVVALPQ------VKQE 501
                 L E ASSP   P  P+ ++     Q    S      S+ +  P       + + 
Sbjct: 600 PPPPPPLPEAASSPPPAPPLPLESAGPGCGQRRSSSSTGSTKSFNMMSPTGDNSELLAEI 659

Query: 502 KADTQDEWTPGTAVLTS-------PVLVPGCPSKAVDPGLPSVKQEPP 542
           KA    + TP +  LT+       P   P  P  +V P L  V+   P
Sbjct: 660 KAGKSLKPTPQSKGLTTVFSGIGQPAFQPDSPLPSVSPALSPVRSPTP 707



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 6/51 (11%)

Query: 259 QRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPP----SQSPEPTEPHP 305
           Q   L G H     GC +   A R     P PPPPP    + SP P  P P
Sbjct: 572 QAALLPGNHV--PNGCAADPKASRELPPPPPPPPPPLPEAASSPPPAPPLP 620


>gi|156139122 CXXC finger 6 [Homo sapiens]
          Length = 2136

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 9/82 (10%)

Query: 326 LQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRL 385
           L P   +++ ++CG C  C ++ +CG C +C ++          Q C+ R+C +   K  
Sbjct: 579 LLPTLEKKKRKRCGVCEPCQQKTNCGECTYCKNR------KNSHQICKKRKCEELKKK-- 630

Query: 386 LPSVWSESEDGAGSPPPYRRRK 407
            PSV    E    +  P R +K
Sbjct: 631 -PSVVVPLEVIKENKRPQREKK 651



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 10/24 (41%), Positives = 15/24 (62%)

Query: 220 ERSRGCGVCRGCQTQEDCGHCPIC 243
           ++ + CGVC  CQ + +CG C  C
Sbjct: 586 KKRKRCGVCEPCQQKTNCGECTYC 609



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 8/45 (17%)

Query: 172 KRVGCGECAACQVTEDCGACSTCL-LQLPHDVASGLFCKCERRRC 215
           KR  CG C  CQ   +CG C+ C   +  H +       C++R+C
Sbjct: 587 KRKRCGVCEPCQQKTNCGECTYCKNRKNSHQI-------CKKRKC 624


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 17/30 (56%), Positives = 18/30 (60%)

Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPP 313
           PG  PLPPPPP   P+P  P P  L P PP
Sbjct: 685 PGFPPLPPPPPPPPPQPGFPMPPPLPPPPP 714



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 12/26 (46%), Positives = 13/26 (50%)

Query: 288 PLPPPPPSQSPEPTEPHPRALAPSPP 313
           P+PPP P   P P   HP    P PP
Sbjct: 704 PMPPPLPPPPPPPPPAHPAVTVPPPP 729



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 16/160 (10%)

Query: 391 SESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLP 450
           + S+ G   P P     RPSS     + PT  P  +    + D    P      G    P
Sbjct: 548 TNSQPGFRGPTP--PSSRPSSTGLEDISPTPLPD-SDEDEELDLGLGPRPPPEPG----P 600

Query: 451 PPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVA---LPQVKQEKADTQD 507
           P    L  L + A   + + G    ++E + +  Q SG    ++   +P      AD   
Sbjct: 601 PDPAGL--LSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPK 658

Query: 508 EW--TPGTAVLTSP-VLVPGCPSKAVDPGLPSVKQEPPDP 544
               TPG A + +P VL P  P     PG P +   PP P
Sbjct: 659 PMVVTPGAAAVAAPSVLAPTLPLPP-PPGFPPLPPPPPPP 697



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 2/28 (7%)

Query: 288 PLPPPP--PSQSPEPTEPHPRALAPSPP 313
           PLPPPP  P   P P  P P+   P PP
Sbjct: 680 PLPPPPGFPPLPPPPPPPPPQPGFPMPP 707


>gi|239754911 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 297

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 14/114 (12%)

Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPR----PGLRRQWKCVQRRCLRG 265
           C  R    +  R +  G    C     C  CP    PPR    P L       +R C   
Sbjct: 109 CHHRPRYHLRRRPQPHGAASSCSLPR-CRLCPERSAPPRRRGPPPLPTSCHWARRSC--- 164

Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPRALAPSPPAE 315
             A R+GG  S       P A P  P PP  SP P      P P A +  PP +
Sbjct: 165 --ALRRGGAASWRRGPGTPAAAPEAPSPPDHSPSPWTSRCPPCPHASSFLPPGQ 216


>gi|239749451 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 297

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 14/114 (12%)

Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPR----PGLRRQWKCVQRRCLRG 265
           C  R    +  R +  G    C     C  CP    PPR    P L       +R C   
Sbjct: 109 CHHRPRYHLRRRPQPHGAASSCSLPR-CRLCPERSAPPRRRGPPPLPTSCHWARRSC--- 164

Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPRALAPSPPAE 315
             A R+GG  S       P A P  P PP  SP P      P P A +  PP +
Sbjct: 165 --ALRRGGAASWRRGPGTPAAAPEAPSPPDHSPSPWTSRCPPCPHASSFLPPGQ 216


>gi|239743581 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 297

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 14/114 (12%)

Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPR----PGLRRQWKCVQRRCLRG 265
           C  R    +  R +  G    C     C  CP    PPR    P L       +R C   
Sbjct: 109 CHHRPRYHLRRRPQPHGAASSCSLPR-CRLCPERSAPPRRRGPPPLPTSCHWARRSC--- 164

Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP----TEPHPRALAPSPPAE 315
             A R+GG  S       P A P  P PP  SP P      P P A +  PP +
Sbjct: 165 --ALRRGGAASWRRGPGTPAAAPEAPSPPDHSPSPWTSRCPPCPHASSFLPPGQ 216


>gi|158261990 CXXC finger 5 [Homo sapiens]
          Length = 322

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 6/54 (11%)

Query: 330 TNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 383
           + +++ ++CG CA C RR++C +C  C ++ K G      Q C++R+C +   K
Sbjct: 255 SGKKKRKRCGMCAPCRRRINCEQCSSCRNR-KTG-----HQICKFRKCEELKKK 302



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 172 KRVGCGECAACQVTEDCGACSTCL-LQLPHDVASGLFCKCE 211
           KR  CG CA C+   +C  CS+C   +  H +    F KCE
Sbjct: 259 KRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICK--FRKCE 297


>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
          Length = 580

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)

Query: 14  GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
           GW+R    R  G T GR D Y+ SP G + RSK  L  YL    + +L    FDF    K
Sbjct: 89  GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148

Query: 66  QGI 68
           +GI
Sbjct: 149 RGI 151


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 2/63 (3%)

Query: 284  PGAQPLPPPPPSQSPEPTEPHPRALAP--SPPAEFIYYCVDEDELQPYTNRRQNRKCGAC 341
            P   PLPPPPP   P P  P P A AP  +PP E      ++ EL         +K    
Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555

Query: 342  AAC 344
            A C
Sbjct: 1556 AVC 1558



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 1/31 (3%)

Query: 284  PGAQP-LPPPPPSQSPEPTEPHPRALAPSPP 313
            P  QP LP PPP  +P P+ P P  L P PP
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPP 1506



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 16/51 (31%), Positives = 19/51 (37%)

Query: 263  LRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPP 313
            L G  +    G         +P   P P P P   P P  P P+   PSPP
Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP 1486



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 10/79 (12%)

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           P+ L PP P L      V         +  K G      A R    QP PPPPP   P P
Sbjct: 791 PLVLPPPPPQLLPS---VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847

Query: 301 --TEPHPRA-----LAPSP 312
              E H R+      APSP
Sbjct: 848 LQLEAHLRSHGLEPAAPSP 866


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 38.5 bits (88), Expect = 0.018
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 279  AARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPA 314
            A  + P  QP PPPPP Q P P  P P+A    PPA
Sbjct: 2502 AVAQPPPPQPQPPPPP-QQPPPPLPQPQAAGSQPPA 2536



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 4/89 (4%)

Query: 454  TDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGT 513
            T +  +++ AS+  Q      A T+A     Q   +  V A  QV Q+K   Q   T  +
Sbjct: 3018 TPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTAS 3077

Query: 514  AVLTSPVLVPGCPSKAVDPGLPSVKQEPP 542
            A    P+  PG P+ A  P       + P
Sbjct: 3078 A----PLQTPGAPNPAQVPASSDSPSQQP 3102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,237,876
Number of Sequences: 37866
Number of extensions: 2054551
Number of successful extensions: 23977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 266
Number of HSP's successfully gapped in prelim test: 362
Number of HSP's that attempted gapping in prelim test: 18123
Number of HSP's gapped (non-prelim): 5044
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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