Search of human proteins with 21450863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21450863 attractin isoform 2 [Homo sapiens]
         (1272 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21450863 attractin isoform 2 [Homo sapiens]                       2740   0.0  
gi|21450861 attractin isoform 1 [Homo sapiens]                       2733   0.0  
gi|46410931 attractin-like 1 [Homo sapiens]                          1550   0.0  
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]               213   9e-55
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                  79   3e-14
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...    77   8e-14
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...    77   8e-14
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...    75   4e-13
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                  74   7e-13
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]           73   2e-12
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]          73   2e-12
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]          73   2e-12
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]           73   2e-12
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                 72   3e-12
gi|143770880 laminin, beta 4 [Homo sapiens]                            72   3e-12
gi|22547221 tolloid-like 1 [Homo sapiens]                              72   3e-12
gi|6912724 tolloid-like 2 [Homo sapiens]                               71   8e-12
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]            70   1e-11
gi|219842266 usherin isoform B [Homo sapiens]                          69   2e-11
gi|219842259 usherin isoform A [Homo sapiens]                          69   2e-11
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               69   3e-11
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    68   6e-11
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa...    68   6e-11
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap...    68   6e-11
gi|16945972 kelch domain containing 3 [Homo sapiens]                   68   6e-11
gi|164414431 netrin G1 isoform 1 [Homo sapiens]                        67   1e-10
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                 67   1e-10
gi|126091152 cubilin [Homo sapiens]                                    66   2e-10
gi|50659100 regeneration associated muscle protease isoform b [H...    66   2e-10
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             65   4e-10

>gi|21450863 attractin isoform 2 [Homo sapiens]
          Length = 1272

 Score = 2740 bits (7103), Expect = 0.0
 Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)

Query: 1    MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60
            MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR
Sbjct: 1    MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60

Query: 61   LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120
            LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC
Sbjct: 61   LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120

Query: 121  PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180
            PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE
Sbjct: 121  PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180

Query: 181  CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240
            CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG
Sbjct: 181  CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240

Query: 241  FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300
            FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN
Sbjct: 241  FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300

Query: 301  SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360
            SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM
Sbjct: 301  SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360

Query: 361  FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420
            FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE
Sbjct: 361  FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420

Query: 421  LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480
            LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY
Sbjct: 421  LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480

Query: 481  DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540
            DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD
Sbjct: 481  DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540

Query: 541  TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600
            TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW
Sbjct: 541  TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600

Query: 601  SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660
            SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA
Sbjct: 601  SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660

Query: 661  GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720
            GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC
Sbjct: 661  GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720

Query: 721  HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780
            HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC
Sbjct: 721  HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780

Query: 781  IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840
            IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR
Sbjct: 781  IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840

Query: 841  IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900
            IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS
Sbjct: 841  IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900

Query: 901  TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960
            TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD
Sbjct: 901  TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960

Query: 961  SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020
            SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS
Sbjct: 961  SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020

Query: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080
            YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC
Sbjct: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080

Query: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140
            ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC
Sbjct: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140

Query: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200
            EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS
Sbjct: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200

Query: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260
            KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF
Sbjct: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260

Query: 1261 TWPIKIQVQTEQ 1272
            TWPIKIQVQTEQ
Sbjct: 1261 TWPIKIQVQTEQ 1272


>gi|21450861 attractin isoform 1 [Homo sapiens]
          Length = 1429

 Score = 2733 bits (7084), Expect = 0.0
 Identities = 1268/1272 (99%), Positives = 1269/1272 (99%)

Query: 1    MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60
            MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR
Sbjct: 1    MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60

Query: 61   LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120
            LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC
Sbjct: 61   LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120

Query: 121  PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180
            PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE
Sbjct: 121  PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180

Query: 181  CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240
            CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG
Sbjct: 181  CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240

Query: 241  FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300
            FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN
Sbjct: 241  FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300

Query: 301  SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360
            SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM
Sbjct: 301  SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360

Query: 361  FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420
            FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE
Sbjct: 361  FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420

Query: 421  LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480
            LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY
Sbjct: 421  LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480

Query: 481  DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540
            DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD
Sbjct: 481  DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540

Query: 541  TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600
            TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW
Sbjct: 541  TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600

Query: 601  SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660
            SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA
Sbjct: 601  SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660

Query: 661  GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720
            GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC
Sbjct: 661  GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720

Query: 721  HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780
            HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC
Sbjct: 721  HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780

Query: 781  IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840
            IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR
Sbjct: 781  IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840

Query: 841  IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900
            IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS
Sbjct: 841  IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900

Query: 901  TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960
            TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD
Sbjct: 901  TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960

Query: 961  SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020
            SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS
Sbjct: 961  SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020

Query: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080
            YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC
Sbjct: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080

Query: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140
            ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC
Sbjct: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140

Query: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200
            EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS
Sbjct: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200

Query: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260
            KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF
Sbjct: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260

Query: 1261 TWPIKIQVQTEQ 1272
            TWPIKIQ+   Q
Sbjct: 1261 TWPIKIQIAFSQ 1272


>gi|46410931 attractin-like 1 [Homo sapiens]
          Length = 1379

 Score = 1550 bits (4014), Expect = 0.0
 Identities = 704/1184 (59%), Positives = 892/1184 (75%), Gaps = 35/1184 (2%)

Query: 103  RPCVNGGRCNPG---TGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCT 159
            +PC   G C  G      C+C  GWVG+QCQHC GRF+LT  SG++TDGP NYKYKTKCT
Sbjct: 61   KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT 120

Query: 160  WLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEV 219
            WLIEG PN ++RLRFNHFATECSWDH+YVYDGDSIYAPL+A  SGLIVPE  GNETVPEV
Sbjct: 121  WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV 180

Query: 220  VATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDT-VECECSENWK 278
            V TSGYALLHFFSDAAYNLTGFNI YS + CPNNCSG G+C  S S  + V CEC + WK
Sbjct: 181  VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK 240

Query: 279  GEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338
            GEACDIP+C  NCG P  G C+ +  + C C   WQGP CS+ VP+ +S+W         
Sbjct: 241  GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS 300

Query: 339  --LPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHS 396
              + RASHKAV++G  MWV+GGY FN+S + MVL Y+L S  W  +       + RYGHS
Sbjct: 301  PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIW-NVGTPSRGPLQRYGHS 359

Query: 397  LALYKDKIYMYGGKIDST-GNVTNELRVFHIHNESWVLLTPKAK---EQYAVVGHSAHIV 452
            LALY++ I+MYGG+I++  GNVT+EL VF+IH++SW   TP      +QYAV GHSAHI+
Sbjct: 360  LALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIM 419

Query: 453  TLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTR 512
             L +  VVM++IFG+  +YGY S++QEY +  NTW +  T+GA+VQGGYGH+SVYD  T+
Sbjct: 420  ELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITK 479

Query: 513  ALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGN 572
            ++YVHGGYKA   NKY L DDLY+Y+V+T+ WTILK+S F RYLH+AV+++G ML+FGGN
Sbjct: 480  SIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGN 539

Query: 573  THNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF 632
            THNDTS+S+GAKCFS+DF+AYDIACD W +LP+P+LH DVNRFGHSAV+ N +MY+FGGF
Sbjct: 540  THNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF 599

Query: 633  NSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSE 692
            +S+LL+DILV+    C A R E  C  AGPGI+CVWN   + C SW   +      L+++
Sbjct: 600  SSVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWN--KNHCESWE--SGNTNNILRAK 655

Query: 693  CFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDH-CVPRNHSCSEGQISIFRYENCPKDN 751
            C  K     DRC ++ DC SCTANTN C WC+D  C+  N +CS   +S+  Y  C   N
Sbjct: 656  CPPKTAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCS---MSVKNYTKCHVRN 712

Query: 752  PMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDN 811
                CNK TSC+SC+L+ NCQW+ R QEC ALP ++CG GW  +G++CL++ +++ENYDN
Sbjct: 713  EQI-CNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDN 771

Query: 812  AKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWED 871
            AKL+C N +  LASLTT K+VEFVL ++      Q  ++  ++PWVGLRKIN+SYW WED
Sbjct: 772  AKLYCYNLSGNLASLTTSKEVEFVLDEI------QKYTQQKVSPWVGLRKINISYWGWED 825

Query: 872  MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQ 928
            MSPFTN+ LQW+P EP+D+GFC  L   +  GLKA  C +  NG VCE+P    N +A+ 
Sbjct: 826  MSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARP 885

Query: 929  CRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS 988
            C+ PC+LRT+C +CTS   ECMWCS+ K+CVDSNAY+ SFP+GQC+EW T +TC P+NCS
Sbjct: 886  CKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQT-ATCSPQNCS 944

Query: 989  GYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCL 1048
            G  TC  CLEQPGCGWC DPSNTG+G CIEGS +GP+K+      G  + + +L++++C 
Sbjct: 945  GLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKL-----IGMHHSEMVLDTNLCP 999

Query: 1049 EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQP 1108
            ++  Y WSFI CPACQCNGHS CIN ++CE+C+NLTTGK C+ C+ G+YGDPTNGG+C  
Sbjct: 1000 KEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTA 1059

Query: 1109 CKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFS 1168
            C C+GHA++C+ +TGKCFCTTKG+KGD+CQLC+ ENRY GNPLRGTCYY+LLIDYQFTFS
Sbjct: 1060 CTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFS 1119

Query: 1169 LSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSK 1228
            L QEDDR++TAINF+A P++ N++LD+ INAS NFNLNITW+   +AGT +GEE  +VSK
Sbjct: 1120 LLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSK 1179

Query: 1229 TNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQVQTEQ 1272
             NIKEY+DSFS EKF+FR++PNITF+VYVSNF+WPIKIQ+   Q
Sbjct: 1180 NNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQ 1223


>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
          Length = 2778

 Score =  213 bits (542), Expect = 9e-55
 Identities = 159/536 (29%), Positives = 239/536 (44%), Gaps = 49/536 (9%)

Query: 133 GGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYVYDG 191
           G R  L  + GFVTDG GNY     C WLIE   P   + L F    TEC++D+L+VYDG
Sbjct: 32  GQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDG 91

Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCP 251
           DS   PL+A+ SG   P        P + A+SG  LLH FSDA YNL GFN ++ F +CP
Sbjct: 92  DSPRGPLLASLSGSTRP--------PPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCP 143

Query: 252 NNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFS 311
             C   G+C+         C C   W G  C +  C+  CG    G C +S +  C C  
Sbjct: 144 GGCQSHGQCQPPG-----VCACEPGWGGPDCGLQECSAYCG--SHGTC-ASPLGPCRCEP 195

Query: 312 DWQGPGCSVPVPANQ--SFW----TREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSD 365
            + G  C + +  NQ   +W     R+   + ++  A       G ++ V GG   N++ 
Sbjct: 196 GFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG-LLAVFGGQDLNNAL 254

Query: 366 YNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFH 425
            ++VL Y+ ++  W   + S      R+ H    +   + + GG++ + G++TN++  F 
Sbjct: 255 GDLVL-YNFSANTWESWDLS-PAPAARHSHVAVAWAGSLVLMGGEL-ADGSLTNDVWAFS 311

Query: 426 -IHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDK 484
            +    W LL P A       G + H   L +  V + V  G  P   + S +  + LD 
Sbjct: 312 PLGRGHWELLAPPASSSSGPPGLAGHAAALVDD-VWLYVSGGRTPHDLFSSGLFRFRLDS 370

Query: 485 NT---WSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDT 541
            +   W  +   G       GHS V+   +RAL VHGG++  +A      +    + VD 
Sbjct: 371 TSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDR 430

Query: 542 QMWTILKDSRFF-----RYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIA 596
            +WT LK          R  HTA ++   M+V+GGN H         KC+      Y + 
Sbjct: 431 HVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEE---KCYEDGIFFYHLG 487

Query: 597 CDRW--------SVLPRPDLHHDVNRFGH-SAVLHNSTMYVFGGFNSLLLSDILVF 643
           C +W           P         R+ H +AVL  S + V GG++     D++ +
Sbjct: 488 CHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAY 543



 Score =  143 bits (361), Expect = 9e-34
 Identities = 198/836 (23%), Positives = 298/836 (35%), Gaps = 197/836 (23%)

Query: 103  RPC-VNG------GRCNPGTGQCVCPAGWVGEQCQ------------------HCGGRFR 137
            RPC  NG      G C+  +G C C     G  CQ                   CGGR  
Sbjct: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL 1201

Query: 138  LTGSS-----------------GFVTDGPGNYKYKTKCTWLIEGQ-------PNRI---M 170
            LT  S                 G    GPG     + C W++          P  +   +
Sbjct: 1202 LTNVSSVALGSRRVGGLLPPGGGAARAGPG----LSYCVWVVSATEELQPCAPGTLCPPL 1257

Query: 171  RLRFN-HFATECSWDHLYVYDGDSIYAP---------LVAAFSGLIVPERDGNETVPEVV 220
             L F+   +T C+  ++  +DG   +           L+AAF G     RD   TV    
Sbjct: 1258 TLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCG---QRRDRPLTVQ--- 1311

Query: 221  ATSGYALLHFFSDAAYNLTGFNITYSFDMC----PNNCSGRGECKISNSSDTVE-CECSE 275
            A SG  +LH+ ++ + +  GFN +     C    P +C    EC   + +     C C +
Sbjct: 1312 ALSGLLVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQ 1370

Query: 276  NWKGEACDIPHCTDNCG-FPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEY 334
             W G  C +  C +NC      G CN S +  C C   + GP C+  +   Q  W     
Sbjct: 1371 GWAGPHCRMALCPENCNAHTGAGTCNQS-LGVCICAEGFGGPDCATKLDGGQLVWETLMD 1429

Query: 335  SNLKLPRASH------KAVVNGN--IMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSV 386
            S L    AS         +V+G    +W+ GG          +  Y ++ R W  +    
Sbjct: 1430 SRLSADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGA 1489

Query: 387  NN----VVVRYGHSLALY---KDKIYMYGGKIDSTGNVTNELRVFHIHNESWVL-LTPKA 438
             +       R  H+ A     +  +Y+ GG   + G VT +  V ++    W     P+ 
Sbjct: 1490 EDGGPGPSPRSFHAAAYVPAGRGAMYLLGGL--TAGGVTRDFWVLNLTTLQWRQEKAPQT 1547

Query: 439  KEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQ 498
             E  AV GH+   +T + G + +L++ G+ P  G+   + EY L   TW      G    
Sbjct: 1548 VELPAVAGHT---LTARRG-LSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPT 1603

Query: 499  GGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSR------- 551
            G YGHS+VY   T +LYV GG++ F       + +LY      + W++L  S+       
Sbjct: 1604 GLYGHSAVYHEATDSLYVFGGFR-FHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRM 1662

Query: 552  ---------------------FFRYLHTAVIVSGTMLVFGG-----NTH----------- 574
                                  FR +   + +   +   GG     + H           
Sbjct: 1663 RNVRGSSRGLGQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHA 1722

Query: 575  ----NDTSMSHGAKC----FSSDFMAYDIACDRWSVLPRPDLHHDVN-------RFGHSA 619
                 DT +  G +     FSSD + Y + C+ W +   PDL    +          H+ 
Sbjct: 1723 SALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLL---PDLTRSASVGPPMEESVAHAV 1779

Query: 620  VLHNSTMYVFGGFNSLLLSDILVFT--SEQCDAHRSEAACLAAGPGIRCVW--------- 668
                S +Y+ GGF  + L  +L  T   + C    S  AC  +G    C W         
Sbjct: 1780 AAVGSRLYISGGFGGVALGRLLALTLPPDPCRLLSSPEACNQSG---ACTWCHGACLSGD 1836

Query: 669  -----NTGSSQCISWALATDE-QEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHW 722
                   G S C     + +E +  +  SEC ++    H R  Q  D     A+T  C W
Sbjct: 1837 QAHRLGCGGSPCSPMPRSPEECRRLRTCSECLAR----HPRTLQPGD---GEASTPRCKW 1889

Query: 723  CND----HCVPRNHSC-SEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQW 773
            C +     C+ RN SC SE    I + E     N          C  C  +  C W
Sbjct: 1890 CTNCPEGACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMW 1945



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 27/190 (14%)

Query: 920  RPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTM 979
            R A  S ++C   C+ R  C DC + SS+C WC +   C    AY+A +P G C  W   
Sbjct: 870  RGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDS 929

Query: 980  STCPP--ENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFY 1037
                P   +C G+ TC  CL+   CGWC +  N   G+C++G + GP+         + +
Sbjct: 930  VHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPL----GGGNCSLW 985

Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCP--------ACQCNGHSKCINQSICEKCENLTTGKHC 1089
                L   + L      W++  CP          +C+  + C+N  +  +C       HC
Sbjct: 986  VGEGLGLPVALP---ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC-------HC 1035

Query: 1090 ETCISGFYGD 1099
            +    G+ GD
Sbjct: 1036 Q---RGYQGD 1042



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 77/284 (27%), Positives = 107/284 (37%), Gaps = 78/284 (27%)

Query: 908  TCINPLNGSVCERPANHSAK-QCRTPCALRTACGDCTS------GSSECMWCSNMKQCVD 960
            TC +    +V   P   S    C TPC L   C  C        G   C+W S+++QC+ 
Sbjct: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027

Query: 961  SNAYVASFPFGQCMEWYTMSTCPPENCSGYCT----CSHCLEQPGCGWCTDPSNTGKGKC 1016
             +        G C          PE+CS  C     C+ CL +P CGWC      G G+C
Sbjct: 2028 PSYLPLRCMAGGCGRLLR----GPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRC 2083

Query: 1017 IEGSYKGP---------------VKMPSQ----------APTGNFYPQP----------- 1040
            +EG   GP               +  P +            T N + QP           
Sbjct: 2084 MEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGY 2143

Query: 1041 ----------------LLNSSMCLEDS--RYNWSFI--HCPA-CQCNGHSKCIN---QSI 1076
                             +N S C+E    R ++ F+  +C   C+CN HS+C     +  
Sbjct: 2144 TMDNMTGLCRPVCAQGCVNGS-CVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDH 2202

Query: 1077 CEKCENLTTGKHCETCISGFYGDPTNGGKCQPCK--CNGHASLC 1118
            C  C N T G HCE C+  F G    GG C+PC   C G++ +C
Sbjct: 2203 CLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHIC 2246



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 77/292 (26%), Positives = 112/292 (38%), Gaps = 88/292 (30%)

Query: 924  HSAKQCRTPCALRTACGDCTSGSSECMWCSN-----MKQCVDSNAYVASFPFGQCMEW-- 976
            HS  +CR+ C     C +C   S EC WC N     + +C+  + +      G C  W  
Sbjct: 931  HSEPRCRS-CDGFLTCHECLQ-SHECGWCGNEDNPTLGRCLQGD-FSGPLGGGNCSLWVG 987

Query: 977  ------------YTMSTCPPEN--------CSGYCTC--------------------SHC 996
                        +  + CP  +        C    TC                    SHC
Sbjct: 988  EGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC 1047

Query: 997  ----LEQPGCGWCTDPSNTGKGKCI-EGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDS 1051
                LE  G G C+ P +     C+ +  +   +  P+ AP     P P      C  D 
Sbjct: 1048 NRTCLEDCGHGVCSGPPDF---TCVCDLGWTSDLPPPTPAPGP---PAP-----RCSRD- 1095

Query: 1052 RYNWSFIHCPACQCNGHSKCINQS--ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPC 1109
                       C C+ HS C  +    C++C++ T G+HCE C  G +G+ T    C+PC
Sbjct: 1096 -----------CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144

Query: 1110 KCNGHA----SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNP-LRGTCY 1156
            +CNGH       C+  +G CFC     +G  CQLC     Y G+P   G+C+
Sbjct: 1145 QCNGHGDPRRGHCDNLSGLCFCQDH-TEGAHCQLC--SPGYYGDPRAGGSCF 1193



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 108/449 (24%), Positives = 162/449 (36%), Gaps = 105/449 (23%)

Query: 704  CDQHTDCYSCTANTNDCHWCNDHCVPRNHSCS---EGQISIFRYENCPKDNPMYYCNKKT 760
            C++H DC++CT +   C W        + +CS    G+ ++   E CP       C+++ 
Sbjct: 834  CEEHRDCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP-----LCSQRL 887

Query: 761  SCRSC-ALDQNCQWEPRNQECIAL-------PENICGIGWHLVGNSCLKITTAKENYDNA 812
            +C  C A    C W      C          P   C  GW              ++  ++
Sbjct: 888  TCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCR-GW--------------DDSVHS 932

Query: 813  KLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVG-LRKINVSYWCWED 871
            +  CR+ +     LT  + ++         + + ++ +     + G L   N S W  E 
Sbjct: 933  EPRCRSCDGF---LTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEG 989

Query: 872  MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCIN-PLNGSV-CERP-ANHSAKQ 928
            +        +W  +   D   C +      R    ATC+N PL+    C+R         
Sbjct: 990  LGLPVALPARWAYARCPDVDECRL---GLARCHPRATCLNTPLSYECHCQRGYQGDGISH 1046

Query: 929  CRTPCALRTACGDCTSGSSECMWCSNMKQ--CVDSNAYVASFPFGQCMEWYTMSTCPP-E 985
            C      RT   DC  G      CS      CV    + +  P        T +  PP  
Sbjct: 1047 CN-----RTCLEDCGHGV-----CSGPPDFTCVCDLGWTSDLPPP------TPAPGPPAP 1090

Query: 986  NCSGYCTC---SHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFYP 1038
             CS  C C   SHC ++ G G+C +  +   G    +C  GS+            GN   
Sbjct: 1091 RCSRDCGCSFHSHCRKR-GPGFCDECQDWTWGEHCERCRPGSF------------GN--- 1134

Query: 1039 QPLLNSSMCLEDSRYNWSFIHCPACQCNGH-----SKCINQSICEKCENLTTGKHCETCI 1093
                        SR       C  CQCNGH       C N S    C++ T G HC+ C 
Sbjct: 1135 ---------ATGSR------GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCS 1179

Query: 1094 SGFYGDPTNGGKCQPCKCNGHASLCNTNT 1122
             G+YGDP  GG C   +C G A L N ++
Sbjct: 1180 PGYYGDPRAGGSCFR-ECGGRALLTNVSS 1207



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 37/205 (18%)

Query: 986  NCSGYCTCSHCLEQPGCG---WCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLL 1042
            NCS  C C+   E  G G    C    N  KG   E     P+ + S    G   P    
Sbjct: 2181 NCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCL--PLFVGSAVGGGTCRPCHAF 2238

Query: 1043 ---NSSMCL----------EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089
               NS +C+          E  +Y+            G S+  ++++C  C+N + G+ C
Sbjct: 2239 CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE--DEAVCVNCQNNSYGEKC 2296

Query: 1090 ETCISGFYGDPTNGGKCQPCKCNGHASLC------------NTNTGKCFCTTKGVKGD-- 1135
            E+C+ G++      GKC  C+CNGHA  C            NT TG C  ++   + D  
Sbjct: 2297 ESCLQGYF---LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCY 2353

Query: 1136 ECQLCEVENRYQGNPLRGTCYYTLL 1160
            + Q  +    + G+PL G   Y L+
Sbjct: 2354 KYQCAKCRESFHGSPLGGQQCYRLI 2378



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 46/214 (21%), Positives = 65/214 (30%), Gaps = 52/214 (24%)

Query: 933  CALRTACGDCTSGSSECMWCSNMKQCV--DSNAYVASFPFGQCMEWYTMSTCPPENCSGY 990
            C   ++C  C +    C WC     C      A+      G  +     + CP   C  +
Sbjct: 781  CTSYSSCLGCLADQG-CGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPL--CEEH 837

Query: 991  CTCSHCLEQPGCGWCTDPSNTGKGKCIE-GSYKGPVKMPSQAPTGNFYPQPLLNSSMCLE 1049
              C  C + P C W    S  G   C   G  +G +K P + P       PL +  +  E
Sbjct: 838  RDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECP-------PLCSQRLTCE 890

Query: 1050 DSRYNWSFIHCPACQ-------------------CNGHSKCIN-QSICEKCENLTTGKHC 1089
            D   N S   C  CQ                   C G    ++ +  C  C+   T   C
Sbjct: 891  DCLANSS--QCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHEC 948

Query: 1090 -----------------ETCISGFYGDPTNGGKC 1106
                               C+ G +  P  GG C
Sbjct: 949  LQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNC 982



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 54/238 (22%), Positives = 76/238 (31%), Gaps = 44/238 (18%)

Query: 915  GSVCERPANHSAKQCR-----TPCALR----TACGDCTSGSSECMWCSNMKQ--CVDSNA 963
            GS C  P   S ++CR     + C  R       GD  + +  C WC+N  +  C+  N 
Sbjct: 1845 GSPCS-PMPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNG 1903

Query: 964  YVASFPFGQCM----EWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGK---- 1015
               S     C     E +    C    C G   C  C  +  C W      TG+ +    
Sbjct: 1904 SCTSE--NDCRINQREVFWAGNCSEAAC-GAADCEQCTREGKCMWTRQFKRTGETRRILS 1960

Query: 1016 --------CIEGSYKGPVKMPSQAPTGNFYPQP---LLNSSMCLEDSRYNWSFIHC---- 1060
                    C   S      MP ++      P P   L N + CL+    +  + HC    
Sbjct: 1961 VQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSS 2020

Query: 1061 PACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLC 1118
               QC   S    + +   C  L  G   E+C  G         +C  C    H   C
Sbjct: 2021 SLQQCLSPSYLPLRCMAGGCGRLLRGP--ESCSLGC----AQATQCALCLRRPHCGWC 2072



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 12/37 (32%), Positives = 19/37 (51%)

Query: 969  PFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWC 1005
            P G  + ++ +      +C+ Y +C  CL   GCGWC
Sbjct: 763  PGGSEISFFFLEPYRSSSCTSYSSCLGCLADQGCGWC 799



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 32/103 (31%), Positives = 38/103 (36%), Gaps = 29/103 (28%)

Query: 932  PCALRTACGDCTSGSSECMWCSNMKQCVDSN-AYVASFPFGQCMEWYTMSTCP--PENCS 988
            PC L ++   C   S  C WC     C+  + A+        C      S  P  PE C 
Sbjct: 1809 PCRLLSSPEACNQ-SGACTWCHGA--CLSGDQAHRLGCGGSPC------SPMPRSPEECR 1859

Query: 989  GYCTCSHCLE------QPG--------CGWCTDPSNTGKGKCI 1017
               TCS CL       QPG        C WCT   N  +G CI
Sbjct: 1860 RLRTCSECLARHPRTLQPGDGEASTPRCKWCT---NCPEGACI 1899



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 8/89 (8%)

Query: 1054 NWSF---IHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCK 1110
            +W F   +    C   G   C     C   +       C  C  G+ G       C P  
Sbjct: 1328 SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCR-CPQGWAGPHCRMALC-PEN 1385

Query: 1111 CNGH--ASLCNTNTGKCFCTTKGVKGDEC 1137
            CN H  A  CN + G C C  +G  G +C
Sbjct: 1386 CNAHTGAGTCNQSLGVCIC-AEGFGGPDC 1413



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 14/51 (27%), Positives = 19/51 (37%)

Query: 79  CEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQC 129
           C+     A     G      +EC   C + G C    G C C  G++G  C
Sbjct: 152 CQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRAC 202


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 40/103 (38%), Positives = 53/103 (51%), Gaps = 14/103 (13%)

Query: 1060 CPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKC----- 1111
            C  C+C+GH+ +C    +C  C + TTG HCE C+ GFYG+P+ G  G CQPC C     
Sbjct: 739  CQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIA 798

Query: 1112 -NGHASLCNTNTGK---CFCTTKGVKGDECQLCEVENRYQGNP 1150
             N  +  C+ N G    C     G  G  C+ C   + Y GNP
Sbjct: 799  SNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERC--ADGYYGNP 839



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 52/184 (28%), Positives = 69/184 (37%), Gaps = 38/184 (20%)

Query: 987  CSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSS- 1045
            C+   T  HC EQ   G+  +PS    G C       P   P    + NF P   LN   
Sbjct: 760  CAHNTTGVHC-EQCLPGFYGEPSRGTPGDC------QPCACPLTIASNNFSPTCHLNDGD 812

Query: 1046 --MC--------------LEDSRYNWSFI---HCPACQCNGHSKCINQSICE-------K 1079
              +C                D  Y    +    C  C C+G+        C+       K
Sbjct: 813  EVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLK 872

Query: 1080 CENLTTGKHCETCISGFYGDPTNGGKCQPCKCN---GHASLCNTNTGKCFCTTKGVKGDE 1136
            C   T G HCE C  GFYGD      C+ C+C+    H+++C+  TG C C    V G +
Sbjct: 873  CLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDC-KPNVTGQQ 931

Query: 1137 CQLC 1140
            C  C
Sbjct: 932  CDQC 935



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 30/68 (44%), Positives = 40/68 (58%), Gaps = 6/68 (8%)

Query: 1077 CEKCENLTTGKHCETCISGFYGDP-TNGGKCQPCKCNGHASL---CNTNTGKCFCT--TK 1130
            C+ C     GKHCE C S +YG+P T GG CQ C CN H S+   C+  +G+C C     
Sbjct: 1476 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGAS 1535

Query: 1131 GVKGDECQ 1138
            G++ DEC+
Sbjct: 1536 GLRCDECE 1543



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 59/239 (24%), Positives = 84/239 (35%), Gaps = 30/239 (12%)

Query: 922  ANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMST 981
            +N+ +  C         C  C  G S   WC   ++C D      + P   C+       
Sbjct: 799  SNNFSPTCHLNDGDEVVCDWCAPGYSGA-WC---ERCADGYYGNPTVPGESCVPCDCSGN 854

Query: 982  CPPENCSGYCT-----CSHCL--------EQPGCGWCTDPSNTGKGKCIEGSYKGPVKMP 1028
              P   +G+C      C  CL        E+   G+  D       +  E   KG     
Sbjct: 855  VDPSE-AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAV 913

Query: 1029 SQAPTGNFYPQPLLNSSMCLE--DSRYNWSFIH-CPACQCNGHSK----CINQSICEKCE 1081
                TG    +P +    C +     Y     H C  C C+        C ++  C  C 
Sbjct: 914  CHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCH-CV 972

Query: 1082 NLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCT--TKGVKGDECQ 1138
                GK C+ C  GFY      G C PC C    + C+  TG+C C   T+GVK +EC+
Sbjct: 973  PGVAGKRCDRCAHGFYA--YQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECE 1029



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 6/80 (7%)

Query: 1077 CEKCENLTTGKHCETCISGFY--GDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKG 1134
            CE C    TG  CE+C+SG+Y       GG CQPC+C+GHA+ CN + G C        G
Sbjct: 709  CE-CPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTG 766

Query: 1135 DECQLCEVENRYQGNPLRGT 1154
              C+ C     + G P RGT
Sbjct: 767  VHCEQC--LPGFYGEPSRGT 784



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 43/146 (29%), Positives = 60/146 (41%), Gaps = 33/146 (22%)

Query: 1016 CIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCI--N 1073
            C  G ++G  K+P+ +  G   P+PL+                 C  C CN HS     N
Sbjct: 1376 CAPGYHRG--KLPAGSDRG---PRPLVAP---------------CVPCSCNNHSDTCDPN 1415

Query: 1074 QSICEKCENLTTGKHCETCISGFYGDPT-NGGKCQPCKC--NGHASLCNT------NTGK 1124
               C  C + T G HC+ C SG+YG  T +   C  C C  +  AS   T      +  +
Sbjct: 1416 TGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFR 1475

Query: 1125 CFCTTKGVKGDECQLCEVENRYQGNP 1150
            C     G +G  C+ C   + Y GNP
Sbjct: 1476 CDACLLGYEGKHCERC--SSSYYGNP 1499



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 68/284 (23%), Positives = 99/284 (34%), Gaps = 65/284 (22%)

Query: 886  EPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANH------SAKQCRTPCALRTAC 939
            +PS+AG C  ++    +      C+   +G+ CER A+       +AK CR       AC
Sbjct: 856  DPSEAGHCDSVTGECLK------CLGNTDGAHCERCADGFYGDAVTAKNCR-------AC 902

Query: 940  GDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWY----TMSTCPPENCSGYCTCSH 995
             +C    S    C       D    V      QC+  Y    +   C P NCS   + S 
Sbjct: 903  -ECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSD 961

Query: 996  CLEQPGCGWCTDPSNTGK--GKCIEG--SYKGPVKMPSQAP---------TGNFYPQPLL 1042
                 G   C  P   GK   +C  G  +Y+     P   P         TG     P  
Sbjct: 962  GCTDEGQCHCV-PGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHT 1020

Query: 1043 NSSMCLEDSRYNWSF---IHCPACQCN----GHSKCINQSICEKCENLTTGKHCETCISG 1095
                C E    +W +   + C AC C+     H +C   +   +C++   G+ C+ C  G
Sbjct: 1021 QGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG 1080

Query: 1096 FYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQL 1139
            +   P     C PC C+                 +G  GD C L
Sbjct: 1081 YRDFPD----CVPCDCD----------------LRGTSGDACNL 1104



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 10/71 (14%)

Query: 1080 CENLTTGKHCETCISGFYGDPTNGGK----------CQPCKCNGHASLCNTNTGKCFCTT 1129
            C   T G  C+ C  G++      G           C PC CN H+  C+ NTGKC    
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCG 1423

Query: 1130 KGVKGDECQLC 1140
                GD C +C
Sbjct: 1424 DNTAGDHCDVC 1434



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 54/253 (21%), Positives = 84/253 (33%), Gaps = 31/253 (12%)

Query: 889  DAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSE 948
            + G C    +P+  G +   C++   G      + H  + C    A   + G    G   
Sbjct: 917  ETGLCDC--KPNVTGQQCDQCLHGYYGL----DSGHGCRPCNCSVAGSVSDGCTDEGQCH 970

Query: 949  CMWCSNMKQCVDSNAYVASFPFGQCMEW---YTMSTCPPENCSGYCTCSHCLEQPGCGWC 1005
            C+     K+C        ++  G C      +T +TC PE  +G C C    +   C  C
Sbjct: 971  CVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPE--TGECVCPPHTQGVKCEEC 1028

Query: 1006 TD-----PSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHC 1060
             D      +  G   C   S  G         TG+   +       C + S     F  C
Sbjct: 1029 EDGHWGYDAEVGCQAC-NCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC 1087

Query: 1061 PACQCN-------------GHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKC 1106
              C C+             G   C+ ++    C+    G  C  C  G +     N   C
Sbjct: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGC 1147

Query: 1107 QPCKCNGHASLCN 1119
             PC C+G + LC+
Sbjct: 1148 SPCFCSGLSHLCS 1160



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 50/197 (25%), Positives = 74/197 (37%), Gaps = 46/197 (23%)

Query: 971  GQCMEWYTMSTCPPENCSG--YCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMP 1028
            G C+ +   S+CP +  +    C C H         C +  N    +C  G ++ P + P
Sbjct: 268  GMCICYGHASSCPWDETTKKLQCQCEH-------NTCGESCN----RCCPGYHQQPWR-P 315

Query: 1029 SQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCP-----ACQCNGHSKCINQSICEKCENL 1083
                +GN       N     +D  Y+ S          A Q  G   CIN      C   
Sbjct: 316  GTVSSGNTCEA--CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN------CLQN 367

Query: 1084 TTGKHCETCISGFYG----DPTNGGKCQPCKCNGHASLCNT--------------NTGKC 1125
            T G +CETCI G+Y      P     C+PC C+   SL +                 G+C
Sbjct: 368  TMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC 427

Query: 1126 FCTTKGVKGDECQLCEV 1142
             C  +G  G++C  C++
Sbjct: 428  PC-KEGYTGEKCDRCQL 443



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 18/133 (13%)

Query: 998  EQPGCGWCT-DPSNTGKGKCIEGSYKGPV---KMPSQAPTGNFYPQPLLNSSMCLEDSRY 1053
            E   C  C  DP  +    CI+      +   K P Q P    Y         C      
Sbjct: 390  EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY-----TGEKCDRCQLG 444

Query: 1054 NWSFIHCPACQCN-----GHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKCQ 1107
               +  C +C CN         C    +C+  EN+  GK C+ C  GFY     N   C 
Sbjct: 445  YKDYPTCVSCGCNPVGSASDEPCTGPCVCK--ENVE-GKACDRCKPGFYNLKEKNPRGCS 501

Query: 1108 PCKCNGHASLCNT 1120
             C C G + +C++
Sbjct: 502  ECFCFGVSDVCSS 514



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)

Query: 101  CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
            CD P      C+P TG+CVCP    G +C+ C
Sbjct: 998  CDCPHTQN-TCDPETGECVCPPHTQGVKCEEC 1028


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
            sapiens]
          Length = 3118

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 57/208 (27%)

Query: 982  CPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVK------- 1026
            C P  C G+          C +C +  G  +C         KC+ G Y  P K       
Sbjct: 754  CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCD--------KCLPGFYGEPTKGTSEDCQ 805

Query: 1027 ---MPSQAPTGNFYPQPLLNSSMCL-----------------EDSRYNWSFI---HCPAC 1063
                P   P+ NF P   L+ S+ L                  +  +    +    C  C
Sbjct: 806  PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC 865

Query: 1064 QCNGH------SKCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS 1116
            QCN +        C + S  C  C+  TTG++CE C  G++GD  +   CQPC+CN   S
Sbjct: 866  QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS 925

Query: 1117 ---LCNTNTGKCFCTTKGVKGDECQLCE 1141
               +C++ TG+C C    V+G  C  C+
Sbjct: 926  FSEVCHSQTGQCECRA-NVQGQRCDKCK 952



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 49/176 (27%), Positives = 73/176 (41%), Gaps = 39/176 (22%)

Query: 978  TMSTCPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029
            T+ TC P  C+G+ +        C +C       +C         +C  G Y     +P+
Sbjct: 1413 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE--------RCALGYYGIVKGLPN 1464

Query: 1030 QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089
                      PL++SS        N+S    P+C   G    ++   C  C     G++C
Sbjct: 1465 DCQQ---CACPLISSSN-------NFS----PSCVAEG----LDDYRCTACPRGYEGQYC 1506

Query: 1090 ETCISGFYGDPTN-GGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLCE 1141
            E C  G+ G P N GG CQ C+C+ + SL   C+  TG C C   G  G +C  C+
Sbjct: 1507 ERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC-RPGATGRKCDGCK 1561



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 1060 CPACQCNGHSKCINQ--SICEKCENLTTGKHCETCISGFYGDPTN-GGKCQPCKC----- 1111
            C  CQCNGHS   +   SIC+ C++ T G  CE C  G+YG        CQ C C     
Sbjct: 1417 CVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISS 1476

Query: 1112 -NGHASLC---NTNTGKCFCTTKGVKGDECQLCEVENRYQGNP 1150
             N  +  C     +  +C    +G +G  C+ C     Y G+P
Sbjct: 1477 SNNFSPSCVAEGLDDYRCTACPRGYEGQYCERC--APGYTGSP 1517



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 11/76 (14%)

Query: 1076 ICEKCENLT--TGKHCETCISGFY------GDPTNG---GKCQPCKCNGHASLCNTNTGK 1124
            + EKC+     +G  CE C+ GFY      G  T G   G C PC+CNGH+SLC+  T  
Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI 1435

Query: 1125 CFCTTKGVKGDECQLC 1140
            C        GD C+ C
Sbjct: 1436 CQNCQHHTAGDFCERC 1451



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 67/281 (23%), Positives = 95/281 (33%), Gaps = 47/281 (16%)

Query: 918  CERPANHSAKQCRTPCA----LRTACG----DCTSGSSECMWCSNMKQCVDSNAYVASFP 969
            CE  AN   ++C    A    L++A G    +C S  S+   C    QC      V    
Sbjct: 937  CECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPG-VTGKK 995

Query: 970  FGQCMEWYTMSTCPPENCSGYCTCSHCLEQ--PGCGWCTDPSNTGKGKCIEG-------- 1019
              +C   Y         C+  C CSH      P  G C  P NT   KC +         
Sbjct: 996  CDRCAHGYF--NFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052

Query: 1020 ----------SYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC---- 1065
                      S  G +       TG     P  + + C E SR +W++  C  C C    
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG 1112

Query: 1066 ---------NGHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHA 1115
                          C +Q+    C+    G HC+ C  G +G D  N   C  C C G  
Sbjct: 1113 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT 1172

Query: 1116 SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCY 1156
            + C+   G    T   +K ++  L  V+   Q    +G  +
Sbjct: 1173 TQCSEAKG-LIRTWVTLKAEQTILPLVDEALQHTTTKGIVF 1212



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 31/108 (28%)

Query: 1063 CQCNGHSKCI------NQSICEKCENLTTGKHCETCISGFYGDPTNGG------KCQPCK 1110
            C C GH++        N+S CE CE+ T G  C+ C  GF+  P   G      +C+ C 
Sbjct: 287  CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345

Query: 1111 CNGHASLCNTNT------------------GKCFCTTKGVKGDECQLC 1140
            C+G A  C  +                   G C   T+   G  C+ C
Sbjct: 346  CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 1076 ICEKCENLTTGKHCETCISGF--YGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVK 1133
            +C+ C    TG  CE+C            GG C+PC+C GHA  C+  TG+C        
Sbjct: 723  VCQ-CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTG 781

Query: 1134 GDECQLCEVENRYQGNPLRGT 1154
            G  C  C     + G P +GT
Sbjct: 782  GPYCDKC--LPGFYGEPTKGT 800



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 37/127 (29%), Positives = 43/127 (33%), Gaps = 39/127 (30%)

Query: 1060 CPACQCNGHS--------------------KCINQSICEKCENLTTGKHCETCISGFYG- 1098
            C AC C+G +                    K I   +C  C   T G +CETC  GF+  
Sbjct: 341  CEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400

Query: 1099 ---DPTNGGKCQPCKCNGHASL---C---------NTNTGKCFCTTKGVKGDECQLCEVE 1143
                P     CQPC C+   SL   C             G C C T G  G  C  C   
Sbjct: 401  KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT-GFGGVSCDRC--A 457

Query: 1144 NRYQGNP 1150
              Y G P
Sbjct: 458  RGYTGYP 464



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 63/267 (23%), Positives = 88/267 (32%), Gaps = 74/267 (27%)

Query: 95   AAEAKECDRPCVNGGRCNPG----------TGQCVCPAGWVGEQCQHC-GGRFRLTGSSG 143
            A +AK C +PC    RCN G          TGQC C A   G++C  C  G F L  + G
Sbjct: 909  AVDAKNC-QPC----RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARG 963

Query: 144  FVTDGPGNYKYKT-------KCTWLIEG-QPNRIMRLRFNHF------ATECSWDHLYVY 189
             V     ++  K+       +C W   G    +  R    +F       T C   HL   
Sbjct: 964  CVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL--- 1019

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEV--VATSGYALLHFFSDAAYNLTGFNITYSF 247
                                  GN   P+          +    S  A N  G +IT   
Sbjct: 1020 ----------------------GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGC 1057

Query: 248  DMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCT-DNCGFPHRGICN------ 300
              C  NCS  G      + +T +C C   + G  C    C+  +  +P   +C+      
Sbjct: 1058 KAC--NCSTVGSLDFQCNVNTGQCNCHPKFSGAKC--TECSRGHWNYPRCNLCDCFLPGT 1113

Query: 301  -----SSDVRGCSCFSDWQGPGCSVPV 322
                  S+ + CSC        C V V
Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNV 1140


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 57/208 (27%)

Query: 982  CPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVK------- 1026
            C P  C G+          C +C +  G  +C         KC+ G Y  P K       
Sbjct: 754  CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCD--------KCLPGFYGEPTKGTSEDCQ 805

Query: 1027 ---MPSQAPTGNFYPQPLLNSSMCL-----------------EDSRYNWSFI---HCPAC 1063
                P   P+ NF P   L+ S+ L                  +  +    +    C  C
Sbjct: 806  PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC 865

Query: 1064 QCNGH------SKCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS 1116
            QCN +        C + S  C  C+  TTG++CE C  G++GD  +   CQPC+CN   S
Sbjct: 866  QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS 925

Query: 1117 ---LCNTNTGKCFCTTKGVKGDECQLCE 1141
               +C++ TG+C C    V+G  C  C+
Sbjct: 926  FSEVCHSQTGQCECRA-NVQGQRCDKCK 952



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 49/176 (27%), Positives = 73/176 (41%), Gaps = 39/176 (22%)

Query: 978  TMSTCPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029
            T+ TC P  C+G+ +        C +C       +C         +C  G Y     +P+
Sbjct: 1413 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE--------RCALGYYGIVKGLPN 1464

Query: 1030 QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089
                      PL++SS        N+S    P+C   G    ++   C  C     G++C
Sbjct: 1465 DCQQ---CACPLISSSN-------NFS----PSCVAEG----LDDYRCTACPRGYEGQYC 1506

Query: 1090 ETCISGFYGDPTN-GGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLCE 1141
            E C  G+ G P N GG CQ C+C+ + SL   C+  TG C C   G  G +C  C+
Sbjct: 1507 ERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC-RPGATGRKCDGCK 1561



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 1060 CPACQCNGHSKCINQ--SICEKCENLTTGKHCETCISGFYGDPTN-GGKCQPCKC----- 1111
            C  CQCNGHS   +   SIC+ C++ T G  CE C  G+YG        CQ C C     
Sbjct: 1417 CVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISS 1476

Query: 1112 -NGHASLC---NTNTGKCFCTTKGVKGDECQLCEVENRYQGNP 1150
             N  +  C     +  +C    +G +G  C+ C     Y G+P
Sbjct: 1477 SNNFSPSCVAEGLDDYRCTACPRGYEGQYCERC--APGYTGSP 1517



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 11/76 (14%)

Query: 1076 ICEKCENLT--TGKHCETCISGFY------GDPTNG---GKCQPCKCNGHASLCNTNTGK 1124
            + EKC+     +G  CE C+ GFY      G  T G   G C PC+CNGH+SLC+  T  
Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI 1435

Query: 1125 CFCTTKGVKGDECQLC 1140
            C        GD C+ C
Sbjct: 1436 CQNCQHHTAGDFCERC 1451



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 67/281 (23%), Positives = 95/281 (33%), Gaps = 47/281 (16%)

Query: 918  CERPANHSAKQCRTPCA----LRTACG----DCTSGSSECMWCSNMKQCVDSNAYVASFP 969
            CE  AN   ++C    A    L++A G    +C S  S+   C    QC      V    
Sbjct: 937  CECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPG-VTGKK 995

Query: 970  FGQCMEWYTMSTCPPENCSGYCTCSHCLEQ--PGCGWCTDPSNTGKGKCIEG-------- 1019
              +C   Y         C+  C CSH      P  G C  P NT   KC +         
Sbjct: 996  CDRCAHGYF--NFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052

Query: 1020 ----------SYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC---- 1065
                      S  G +       TG     P  + + C E SR +W++  C  C C    
Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG 1112

Query: 1066 ---------NGHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHA 1115
                          C +Q+    C+    G HC+ C  G +G D  N   C  C C G  
Sbjct: 1113 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT 1172

Query: 1116 SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCY 1156
            + C+   G    T   +K ++  L  V+   Q    +G  +
Sbjct: 1173 TQCSEAKG-LIRTWVTLKAEQTILPLVDEALQHTTTKGIVF 1212



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 31/108 (28%)

Query: 1063 CQCNGHSKCI------NQSICEKCENLTTGKHCETCISGFYGDPTNGG------KCQPCK 1110
            C C GH++        N+S CE CE+ T G  C+ C  GF+  P   G      +C+ C 
Sbjct: 287  CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345

Query: 1111 CNGHASLCNTNT------------------GKCFCTTKGVKGDECQLC 1140
            C+G A  C  +                   G C   T+   G  C+ C
Sbjct: 346  CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 1076 ICEKCENLTTGKHCETCISGF--YGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVK 1133
            +C+ C    TG  CE+C            GG C+PC+C GHA  C+  TG+C        
Sbjct: 723  VCQ-CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTG 781

Query: 1134 GDECQLCEVENRYQGNPLRGT 1154
            G  C  C     + G P +GT
Sbjct: 782  GPYCDKC--LPGFYGEPTKGT 800



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 37/127 (29%), Positives = 43/127 (33%), Gaps = 39/127 (30%)

Query: 1060 CPACQCNGHS--------------------KCINQSICEKCENLTTGKHCETCISGFYG- 1098
            C AC C+G +                    K I   +C  C   T G +CETC  GF+  
Sbjct: 341  CEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400

Query: 1099 ---DPTNGGKCQPCKCNGHASL---C---------NTNTGKCFCTTKGVKGDECQLCEVE 1143
                P     CQPC C+   SL   C             G C C T G  G  C  C   
Sbjct: 401  KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT-GFGGVSCDRC--A 457

Query: 1144 NRYQGNP 1150
              Y G P
Sbjct: 458  RGYTGYP 464



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 63/267 (23%), Positives = 88/267 (32%), Gaps = 74/267 (27%)

Query: 95   AAEAKECDRPCVNGGRCNPG----------TGQCVCPAGWVGEQCQHC-GGRFRLTGSSG 143
            A +AK C +PC    RCN G          TGQC C A   G++C  C  G F L  + G
Sbjct: 909  AVDAKNC-QPC----RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARG 963

Query: 144  FVTDGPGNYKYKT-------KCTWLIEG-QPNRIMRLRFNHF------ATECSWDHLYVY 189
             V     ++  K+       +C W   G    +  R    +F       T C   HL   
Sbjct: 964  CVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL--- 1019

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEV--VATSGYALLHFFSDAAYNLTGFNITYSF 247
                                  GN   P+          +    S  A N  G +IT   
Sbjct: 1020 ----------------------GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGC 1057

Query: 248  DMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCT-DNCGFPHRGICN------ 300
              C  NCS  G      + +T +C C   + G  C    C+  +  +P   +C+      
Sbjct: 1058 KAC--NCSTVGSLDFQCNVNTGQCNCHPKFSGAKC--TECSRGHWNYPRCNLCDCFLPGT 1113

Query: 301  -----SSDVRGCSCFSDWQGPGCSVPV 322
                  S+ + CSC        C V V
Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNV 1140


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
           sapiens]
          Length = 986

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 22/156 (14%)

Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWV----GEQCQHCGGRFRLTGSSGFVT--DGPGNYKY 154
           C + CVN      G+ +C C +G+V       C+  G   ++T +SG +T  + P  Y  
Sbjct: 714 CQQDCVN----TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPS 769

Query: 155 KTKCTWLIEGQPNRIMRLRFNHF----ATECSWDHLYVYDGDSIYAPLVAAFSGLIVPER 210
           K +CTW I   P   ++L F         EC++DHL V+DG    AP++  F G   PE 
Sbjct: 770 KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPE- 828

Query: 211 DGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS 246
                   V+AT     L F+SD +    GF  +++
Sbjct: 829 -------PVLATGSRMFLRFYSDNSVQRKGFQASHA 857



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 15/167 (8%)

Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLY 187
           CGG  +         + P +Y+    C W I+      + L F  F  E    C++D+L 
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY-- 245
           V DG S  + L+  + G   P+        ++ +TS    L F SD + N  GF + +  
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPD--------DIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546

Query: 246 SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
             D C     G  E +  N+  + +C C   ++  A D   C   CG
Sbjct: 547 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYE-LAPDKRRCEAACG 592



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 55/198 (27%), Positives = 78/198 (39%), Gaps = 36/198 (18%)

Query: 97  EAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTGSSGFVT 146
           E  EC RP  N G C        G+ +C C  G+       +C+   G F LT  +G +T
Sbjct: 547 EVDECSRP--NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGF-LTKLNGSIT 603

Query: 147 DG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVA 200
               P  Y     C W +       + L+F+ F TE    C +D + V  G +  + L  
Sbjct: 604 SPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHG 663

Query: 201 AFSGLIVPERDGNETVPEVVATSGY--ALLHFFSDAAYNLTGFNITYSFDMCPNNCS-GR 257
            F G   PE          V TS Y    + F SD   +  GF   +  D   + CS   
Sbjct: 664 KFCGSEKPE----------VITSQYNNMRVEFKSDNTVSKKGFKAHFFSD--KDECSKDN 711

Query: 258 GECK--ISNSSDTVECEC 273
           G C+    N+  + EC+C
Sbjct: 712 GGCQQDCVNTFGSYECQC 729



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 16/132 (12%)

Query: 123 GWVGEQCQHCGGRFRLTGSS----GFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFA 178
           G+       CGG+ R    +         G  NY     C W+I  +    + L F  F 
Sbjct: 851 GFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE 910

Query: 179 ----TECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDA 234
               T+C +D++ ++DG    AP +  + G   PE        EV +     L+ F SD 
Sbjct: 911 VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPE--------EVYSAGDSVLVKFHSDD 962

Query: 235 AYNLTGFNITYS 246
                GF++ Y+
Sbjct: 963 TITKKGFHLRYT 974



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 30/122 (24%), Positives = 46/122 (37%), Gaps = 12/122 (9%)

Query: 128 QCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHF----ATECSW 183
           +C  CG   + +  +    + P  Y     C W I   P   + L F       +  C +
Sbjct: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377

Query: 184 DHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI 243
           D++ V DG    APL   F G  +PE         +V+T     + F S + +   GF  
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPE--------PIVSTDSRLWVEFRSSSNWVGKGFFA 429

Query: 244 TY 245
            Y
Sbjct: 430 VY 431


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 66/247 (26%), Positives = 97/247 (39%), Gaps = 32/247 (12%)

Query: 914  NGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQC 973
            + +  ER A     QC          G   S +S    C+ +   + +  Y  + P  QC
Sbjct: 734  DAAALERQATFERYQCHEE-------GLVPSKTSPSEACAPLLISLSTLIYNGALPC-QC 785

Query: 974  MEWYTMST-CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMP 1028
                ++S+ C P    G C C   +    C  C  P   G G    +  + S++G +   
Sbjct: 786  NPQGSLSSECNPHG--GQCLCKPGVVGRRCDLCA-PGYYGFGPTGCQACQCSHEGALSSL 842

Query: 1029 SQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQ--SICEKCENLTTG 1086
             +  +G    +       C    R  W F  C  C CNGH+   N     C  C + T G
Sbjct: 843  CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGG 902

Query: 1087 KHCETCISGFYGDP--TNGGKCQPCKC-------NGHASLCNTNTGK----CFCTTKGVK 1133
            +HCE CI+GF+GDP    GG+C+PC C          A+ C+ +       C C   G  
Sbjct: 903  EHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA-GYT 961

Query: 1134 GDECQLC 1140
            G  C+ C
Sbjct: 962  GLRCEAC 968



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 68/246 (27%), Positives = 95/246 (38%), Gaps = 44/246 (17%)

Query: 921  PANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMS 980
            P    A QC    AL + C + TSG   C   +   +C         FP           
Sbjct: 825  PTGCQACQCSHEGALSSLC-EKTSGQCLCRTGAFGLRCDRCQRGQWGFP----------- 872

Query: 981  TCPPENCSGYCTCSHCLEQPG-CGWCTDPSNTGKG---KCIEGSYKGPVKMPSQAPTGNF 1036
            +C P  C+G+     C    G C  C D  +TG     +CI G + G  ++P     G  
Sbjct: 873  SCRPCVCNGHA--DECNTHTGACLGCRD--HTGGEHCERCIAG-FHGDPRLPYG---GQC 924

Query: 1037 YPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGF 1096
             P P      C E       F    A  C  H    +Q I   C    TG  CE C  G 
Sbjct: 925  RPCP------CPEGPGSQRHF----ATSC--HQDEYSQQIVCHCRAGYTGLRCEACAPGH 972

Query: 1097 YGDPTN-GGKCQPCKCNGH-----ASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNP 1150
            +GDP+  GG+CQ C+C+G+        C+ +TG+C       +G  C  C  +  + G  
Sbjct: 973  FGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHC--KPGFHGQA 1030

Query: 1151 LRGTCY 1156
             R +C+
Sbjct: 1031 ARQSCH 1036



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 30/110 (27%)

Query: 1060 CPACQCNGHSKC-------------INQSICEKCENLTTGKHCETCISGFYGDPT----N 1102
            C  C+C+GH+               ++  +C+ C++ T G+HCE C   FY DPT    +
Sbjct: 344  CRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRD 403

Query: 1103 GGKCQPCKCNGHAS----LCNTN--------TGKCFCTTKGVKGDECQLC 1140
               C+ C C+   S     C+++        +G+C C  + V G  CQ C
Sbjct: 404  PAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRC-KEHVVGTRCQQC 452



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 62/270 (22%), Positives = 92/270 (34%), Gaps = 71/270 (26%)

Query: 929  CRTPCALRTACGDCTSGSSECMWC------SNMKQCVDSNAYVASFPFG-QCM------- 974
            CR PC       +C + +  C+ C       + ++C+         P+G QC        
Sbjct: 874  CR-PCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEG 932

Query: 975  ---EWYTMSTCPPENCSGYCTCSHC------LEQPGC--GWCTDPSNTGKGKCIEGSYKG 1023
               + +  ++C  +  S    C HC      L    C  G   DPS  G G+C      G
Sbjct: 933  PGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDPSRPG-GRCQLCECSG 990

Query: 1024 PVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCE-N 1082
             +      P       P  ++  CL    ++    HC  C+   H +   QS C +C  N
Sbjct: 991  NID-----PMDPDACDP--HTGQCLR-CLHHTEGPHCAHCKPGFHGQAARQS-CHRCTCN 1041

Query: 1083 L----------------------------TTGKHCETCISGFYGDPTNGGKCQPCKCN-- 1112
            L                              G  C+ C   F+ + T+G  CQPC C+  
Sbjct: 1042 LLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW-NLTSGHGCQPCACHPS 1100

Query: 1113 -GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141
                  CN  TG+C C   G  G  C  C+
Sbjct: 1101 RARGPTCNEFTGQCHCRA-GFGGRTCSECQ 1129



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 7/68 (10%)

Query: 1079 KCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASL-----CNTNTGKCFCTTKGV 1132
            +C+    G  C+ C  GF+G   ++   C+ C+CN   ++     C+ N+G C+C  + V
Sbjct: 439  RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYC-KRLV 497

Query: 1133 KGDECQLC 1140
             G  C  C
Sbjct: 498  TGRGCDRC 505



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 38/149 (25%), Positives = 53/149 (35%), Gaps = 29/149 (19%)

Query: 982  CP-PENC-----SGYCTCSHCLEQPGCGWCTD---PSNTGKG----KCIEGSYKGPVKMP 1028
            CP P+ C     SG C C   ++ P C  C        +G G     C     +GP    
Sbjct: 1050 CPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPT--- 1106

Query: 1029 SQAPTGNFYPQPLLNSSMCLEDSRYNWS--FIHCPACQCNGHSKCINQSICEK------C 1080
                TG  + +       C E    +W    + C AC C+  S+ I+   C +      C
Sbjct: 1107 CNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD--SRGIDTPQCHRFTGHCSC 1164

Query: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPC 1109
                +G  C+ C  GF G       C PC
Sbjct: 1165 RPGVSGVRCDQCARGFSG---IFPACHPC 1190



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 15/44 (34%), Positives = 21/44 (47%)

Query: 100 ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSG 143
           +C+        CNP  GQC+C  G VG +C  C   +   G +G
Sbjct: 784 QCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG 827



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 14/32 (43%), Positives = 15/32 (46%)

Query: 101  CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
            C      G  CN  TGQC C AG+ G  C  C
Sbjct: 1097 CHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 12/41 (29%), Positives = 17/41 (41%)

Query: 92  GSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
           G    +A +C         C   +GQC+C  G  G +C  C
Sbjct: 824 GPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRC 864



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 98   AKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRF 136
            A +CD   ++  +C+  TG C C  G  G +C  C   F
Sbjct: 1142 ACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180


>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
          Length = 3333

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%)

Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114
            C  C CNGHS +C + S IC  C++ T G+HCE C  G+YG+  + G C+ C C   N  
Sbjct: 1684 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 1742

Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155
            A+ C  N G   C+ K G  G +C+ C     Y GNP +  G+C
Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 1784



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 50/181 (27%), Positives = 72/181 (39%), Gaps = 32/181 (17%)

Query: 982  CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG--KCIEGSYKGPVKMPS-------QAP 1032
            C P   +G     HC  + G   C  P+  G+   +C  G Y  P   P        +  
Sbjct: 1268 CHPTGATG----PHCSPEGGQCPC-QPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEM 1322

Query: 1033 TGNFYPQPLLNSSMCLEDSRYNWSF---IHCPACQCNGHS-------KCINQSICEKCEN 1082
            TG     P      C     +++SF     C  C C+          +C   S   +C+ 
Sbjct: 1323 TGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382

Query: 1083 LTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKGVKGDECQL 1139
              TG+ C+ C SGFY  P    +C PC CN   +   +C+  TG C C  + V+G EC +
Sbjct: 1383 RITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGACLC-KENVEGTECNV 1437

Query: 1140 C 1140
            C
Sbjct: 1438 C 1438



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 4/78 (5%)

Query: 1080 CENLTTGKHCETCISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDEC 1137
            C     G  C+ C  G+Y D      G+C PC CNGH++ C   +G C        G+ C
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHC 1715

Query: 1138 QLCEVENRYQGNPLRGTC 1155
            + C  +  Y GN + G+C
Sbjct: 1716 ERC--QEGYYGNAVHGSC 1731



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 14/125 (11%)

Query: 1035 NFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICE------KCENLTTGKH 1088
            +FY  P   S  C   +R   +F H  A  C  H        C        C+    G+ 
Sbjct: 1236 SFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQ 1295

Query: 1089 CETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQG 1148
            C  C +G YG P    +C+PC C     LC   TG+C C  + V+  +C++CE  + +  
Sbjct: 1296 CTRCATGHYGFP----RCKPCSCG--RRLCEEMTGQCRCPPRTVR-PQCEVCETHS-FSF 1347

Query: 1149 NPLRG 1153
            +P+ G
Sbjct: 1348 HPMAG 1352



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%)

Query: 982  CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037
            C P NC+G+   + C  Q G G C +  +   G    +C EG Y   V    +A      
Sbjct: 1684 CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 1734

Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096
            P P  NS                  C  NG   +C        C+   TG  CE C  G+
Sbjct: 1735 PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 1773

Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140
            +G+P   GG CQPC CN +  L  C+  TG C       ++   + D+C  C
Sbjct: 1774 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 27/114 (23%)

Query: 1055 WSFIH-CPACQCNGH-SKCINQ-------------------SICEKCENLTTGKHCETCI 1093
            W   H C AC C+GH S C                       +C  C++ T G +CE C 
Sbjct: 347  WEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCA 406

Query: 1094 SGF---YGDPTNG-GKCQPCKCN-GHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142
             G+   YG P +    C PC C+  HA  C   +G+C C      GD C+ C +
Sbjct: 407  KGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHC-KPNFHGDNCEKCAI 459



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 15/79 (18%)

Query: 1065 CNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTN 1121
            C+ H +C+       C     G  C+TC SGFY  P     CQ C C+   S    C++ 
Sbjct: 503  CDAHGRCL-------CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQMPCSSV 551

Query: 1122 TGKCFCTTKGVKGDECQLC 1140
            TG+C C   GV G  C  C
Sbjct: 552  TGQCEC-RPGVTGQRCDRC 569



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 8/92 (8%)

Query: 1055 WSFIHCPACQCN--GHSKCINQSICEKCENL--TTGKHCETCISGFYGDPTNGGKCQPCK 1110
            +SF  C AC C+  G  +    S+  +CE     TG+ C+ C+SG Y  P   G    C 
Sbjct: 528  YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC- 586

Query: 1111 CNGHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142
                A   N+N G C C    V+G  C  C++
Sbjct: 587  --DPAGTINSNLGYCQCKLH-VEGPTCSRCKL 615



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/266 (22%), Positives = 94/266 (35%), Gaps = 69/266 (25%)

Query: 896  LSEPSTRGLKAATCINPLNG-SVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSN 954
            L  P   G +  TC +      +C+     +    + PC+  T   +C  G +       
Sbjct: 510  LCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTG----QR 565

Query: 955  MKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS----GYCTCSHCLEQPGCGWCTDPSN 1010
              +C+ S AY   FP  Q     + S C P        GYC C   +E P C  C     
Sbjct: 566  CDRCL-SGAY--DFPHCQG----SSSACDPAGTINSNLGYCQCKLHVEGPTCSRC----- 613

Query: 1011 TGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSK 1070
                K +  +      +  + P+G                         C  C+C+    
Sbjct: 614  ----KLLYWN------LDKENPSG-------------------------CSECKCHKAGT 638

Query: 1071 CINQSICEK------CENLTTGKHCETCISGFYG-DPTNGGKCQPCKCN---GHASLCNT 1120
                  C +      C++   G  C+TC  G++  + +N   CQ C+C+     +S+C+ 
Sbjct: 639  VSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698

Query: 1121 NTGKCFCTTKGVKGDECQLCEVENRY 1146
             +G C C  + V G  CQ    EN Y
Sbjct: 699  PSGVCQC-REHVVGKVCQ--RPENNY 721



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 65/303 (21%), Positives = 96/303 (31%), Gaps = 95/303 (31%)

Query: 909  CINPLNGSVCERPANHSAKQCRTPCALRTA---CGDCTSGSSECMWCSNMKQCVDSNAYV 965
            C+   +  VC    N+  K  R  C   T    C  C +G ++  W              
Sbjct: 299  CVCNGHAEVCN--INNPEKLFRCECQHHTCGETCDRCCTGYNQRRW-------------- 342

Query: 966  ASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQP----------------GCGWCTDPS 1009
                  +   W     C   NC G+   S+C   P                G G C +  
Sbjct: 343  ------RPAAWEQSHECEACNCHGHA--SNCYYDPDVERQQASLNTQGIYAGGGVCINCQ 394

Query: 1010 NTGKG----KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC 1065
            +   G    +C +G Y+ P  +P  AP G            C  D        H   C+ 
Sbjct: 395  HNTAGVNCEQCAKGYYR-PYGVPVDAPDGCI---------PCSCDPE------HADGCE- 437

Query: 1066 NGHSKCINQSICEKCENLTTGKHCETCISGFYGDP-----------------TNGGKCQP 1108
             G  +C        C+    G +CE C  G+Y  P                    G  + 
Sbjct: 438  QGSGRC-------HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490

Query: 1109 CKCNGHA---SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQF 1165
            C CN       +C+ + G+C C   GV+G  C  C   + +   P+   C+ + L  YQ 
Sbjct: 491  CDCNLEGVLPEICDAH-GRCLC-RPGVEGPRCDTC--RSGFYSFPICQACWCSALGSYQM 546

Query: 1166 TFS 1168
              S
Sbjct: 547  PCS 549



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 9/84 (10%)

Query: 245 YSFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEAC--------DIPHCTDNCGFPH 295
           YSF +C    CS  G  ++  SS T +CEC     G+ C        D PHC  +     
Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587

Query: 296 RGICNSSDVRGCSCFSDWQGPGCS 319
                +S++  C C    +GP CS
Sbjct: 588 PAGTINSNLGYCQCKLHVEGPTCS 611



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 50/220 (22%), Positives = 70/220 (31%), Gaps = 46/220 (20%)

Query: 915  GSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCM 974
            G  C    N   +QC       T C     G   C  CS  ++  +          GQC 
Sbjct: 1282 GGQCPCQPNVIGRQC-------TRCATGHYGFPRCKPCSCGRRLCEEMT-------GQCR 1327

Query: 975  EWYTMSTCPPENCSGYCTC--SHCLE---QPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029
                   CPP      C    +H        GC  C    N  +   IE +      MP 
Sbjct: 1328 -------CPPRTVRPQCEVCETHSFSFHPMAGCEGC----NCSRRGTIEAA------MPE 1370

Query: 1030 -QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEK------CEN 1082
                +G    +P +    C   +   + F  C  C CN         +C+       C+ 
Sbjct: 1371 CDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT--EPGVCDPGTGACLCKE 1428

Query: 1083 LTTGKHCETCISG-FYGDPTNGGKCQPCKCNGHASLCNTN 1121
               G  C  C  G F+ DP N   C  C C G  + C+++
Sbjct: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSS 1468



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 10/59 (16%)

Query: 101  CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFVTDGPGNYKYKTKC 158
            C+R     G C+PGTG C+C     G +C  C  G F L          P N K  T C
Sbjct: 1407 CNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL---------DPANLKGCTSC 1456



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 5/45 (11%)

Query: 100  ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGF 144
            EC      G  C+P  GQC C    +G QC  C      TG  GF
Sbjct: 1267 ECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA-----TGHYGF 1306



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 1/31 (3%)

Query: 103  RPCVNGGR-CNPGTGQCVCPAGWVGEQCQHC 132
            +PC  G R C   TGQC CP   V  QC+ C
Sbjct: 1310 KPCSCGRRLCEEMTGQCRCPPRTVRPQCEVC 1340



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%)

Query: 254 CSGRGE-CKISNSSDTVECECSENWKGEACD 283
           C+G  E C I+N      CEC  +  GE CD
Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCD 331



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%)

Query: 89   AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132
            AV GS  A    C  P  N    G   N G  +C C AG+ G QC+ C
Sbjct: 1726 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769


>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
          Length = 1668

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%)

Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114
            C  C CNGHS +C + S IC  C++ T G+HCE C  G+YG+  + G C+ C C   N  
Sbjct: 75   CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 133

Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155
            A+ C  N G   C+ K G  G +C+ C     Y GNP +  G+C
Sbjct: 134  ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 175



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%)

Query: 982  CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037
            C P NC+G+   + C  Q G G C +  +   G    +C EG Y   V    +A      
Sbjct: 75   CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 125

Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096
            P P  NS                  C  NG   +C        C+   TG  CE C  G+
Sbjct: 126  PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 164

Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140
            +G+P   GG CQPC CN +  L  C+  TG C       ++   + D+C  C
Sbjct: 165  FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 216



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 1092 CISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGN 1149
            C  G+Y D      G+C PC CNGH++ C   +G C        G+ C+ C  +  Y GN
Sbjct: 59   CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC--QEGYYGN 116

Query: 1150 PLRGTC 1155
             + G+C
Sbjct: 117  AVHGSC 122



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%)

Query: 89  AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132
           AV GS  A    C  P  N    G   N G  +C C AG+ G QC+ C
Sbjct: 117 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 160


>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
          Length = 3277

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%)

Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114
            C  C CNGHS +C + S IC  C++ T G+HCE C  G+YG+  + G C+ C C   N  
Sbjct: 1684 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 1742

Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155
            A+ C  N G   C+ K G  G +C+ C     Y GNP +  G+C
Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 1784



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 50/181 (27%), Positives = 72/181 (39%), Gaps = 32/181 (17%)

Query: 982  CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG--KCIEGSYKGPVKMPS-------QAP 1032
            C P   +G     HC  + G   C  P+  G+   +C  G Y  P   P        +  
Sbjct: 1268 CHPTGATG----PHCSPEGGQCPC-QPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEM 1322

Query: 1033 TGNFYPQPLLNSSMCLEDSRYNWSF---IHCPACQCNGHS-------KCINQSICEKCEN 1082
            TG     P      C     +++SF     C  C C+          +C   S   +C+ 
Sbjct: 1323 TGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382

Query: 1083 LTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKGVKGDECQL 1139
              TG+ C+ C SGFY  P    +C PC CN   +   +C+  TG C C  + V+G EC +
Sbjct: 1383 RITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGACLC-KENVEGTECNV 1437

Query: 1140 C 1140
            C
Sbjct: 1438 C 1438



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 4/78 (5%)

Query: 1080 CENLTTGKHCETCISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDEC 1137
            C     G  C+ C  G+Y D      G+C PC CNGH++ C   +G C        G+ C
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHC 1715

Query: 1138 QLCEVENRYQGNPLRGTC 1155
            + C  +  Y GN + G+C
Sbjct: 1716 ERC--QEGYYGNAVHGSC 1731



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 14/125 (11%)

Query: 1035 NFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICE------KCENLTTGKH 1088
            +FY  P   S  C   +R   +F H  A  C  H        C        C+    G+ 
Sbjct: 1236 SFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQ 1295

Query: 1089 CETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQG 1148
            C  C +G YG P    +C+PC C     LC   TG+C C  + V+  +C++CE  + +  
Sbjct: 1296 CTRCATGHYGFP----RCKPCSCG--RRLCEEMTGQCRCPPRTVR-PQCEVCETHS-FSF 1347

Query: 1149 NPLRG 1153
            +P+ G
Sbjct: 1348 HPMAG 1352



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%)

Query: 982  CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037
            C P NC+G+   + C  Q G G C +  +   G    +C EG Y   V    +A      
Sbjct: 1684 CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 1734

Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096
            P P  NS                  C  NG   +C        C+   TG  CE C  G+
Sbjct: 1735 PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 1773

Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140
            +G+P   GG CQPC CN +  L  C+  TG C       ++   + D+C  C
Sbjct: 1774 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 27/114 (23%)

Query: 1055 WSFIH-CPACQCNGH-SKCINQ-------------------SICEKCENLTTGKHCETCI 1093
            W   H C AC C+GH S C                       +C  C++ T G +CE C 
Sbjct: 347  WEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCA 406

Query: 1094 SGF---YGDPTNG-GKCQPCKCN-GHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142
             G+   YG P +    C PC C+  HA  C   +G+C C      GD C+ C +
Sbjct: 407  KGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHC-KPNFHGDNCEKCAI 459



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 15/79 (18%)

Query: 1065 CNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTN 1121
            C+ H +C+       C     G  C+TC SGFY  P     CQ C C+   S    C++ 
Sbjct: 503  CDAHGRCL-------CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQMPCSSV 551

Query: 1122 TGKCFCTTKGVKGDECQLC 1140
            TG+C C   GV G  C  C
Sbjct: 552  TGQCEC-RPGVTGQRCDRC 569



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 8/92 (8%)

Query: 1055 WSFIHCPACQCN--GHSKCINQSICEKCENL--TTGKHCETCISGFYGDPTNGGKCQPCK 1110
            +SF  C AC C+  G  +    S+  +CE     TG+ C+ C+SG Y  P   G    C 
Sbjct: 528  YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC- 586

Query: 1111 CNGHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142
                A   N+N G C C    V+G  C  C++
Sbjct: 587  --DPAGTINSNLGYCQCKLH-VEGPTCSRCKL 615



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 59/266 (22%), Positives = 94/266 (35%), Gaps = 69/266 (25%)

Query: 896  LSEPSTRGLKAATCINPLNG-SVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSN 954
            L  P   G +  TC +      +C+     +    + PC+  T   +C  G +       
Sbjct: 510  LCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTG----QR 565

Query: 955  MKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS----GYCTCSHCLEQPGCGWCTDPSN 1010
              +C+ S AY   FP  Q     + S C P        GYC C   +E P C  C     
Sbjct: 566  CDRCL-SGAY--DFPHCQG----SSSACDPAGTINSNLGYCQCKLHVEGPTCSRC----- 613

Query: 1011 TGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSK 1070
                K +  +      +  + P+G                         C  C+C+    
Sbjct: 614  ----KLLYWN------LDKENPSG-------------------------CSECKCHKAGT 638

Query: 1071 CINQSICEK------CENLTTGKHCETCISGFYG-DPTNGGKCQPCKCN---GHASLCNT 1120
                  C +      C++   G  C+TC  G++  + +N   CQ C+C+     +S+C+ 
Sbjct: 639  VSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698

Query: 1121 NTGKCFCTTKGVKGDECQLCEVENRY 1146
             +G C C  + V G  CQ    EN Y
Sbjct: 699  PSGVCQC-REHVVGKVCQ--RPENNY 721



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 65/303 (21%), Positives = 96/303 (31%), Gaps = 95/303 (31%)

Query: 909  CINPLNGSVCERPANHSAKQCRTPCALRTA---CGDCTSGSSECMWCSNMKQCVDSNAYV 965
            C+   +  VC    N+  K  R  C   T    C  C +G ++  W              
Sbjct: 299  CVCNGHAEVCN--INNPEKLFRCECQHHTCGETCDRCCTGYNQRRW-------------- 342

Query: 966  ASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQP----------------GCGWCTDPS 1009
                  +   W     C   NC G+   S+C   P                G G C +  
Sbjct: 343  ------RPAAWEQSHECEACNCHGHA--SNCYYDPDVERQQASLNTQGIYAGGGVCINCQ 394

Query: 1010 NTGKG----KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC 1065
            +   G    +C +G Y+ P  +P  AP G            C  D        H   C+ 
Sbjct: 395  HNTAGVNCEQCAKGYYR-PYGVPVDAPDGCI---------PCSCDPE------HADGCE- 437

Query: 1066 NGHSKCINQSICEKCENLTTGKHCETCISGFYGDP-----------------TNGGKCQP 1108
             G  +C        C+    G +CE C  G+Y  P                    G  + 
Sbjct: 438  QGSGRC-------HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490

Query: 1109 CKCNGHA---SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQF 1165
            C CN       +C+ + G+C C   GV+G  C  C   + +   P+   C+ + L  YQ 
Sbjct: 491  CDCNLEGVLPEICDAH-GRCLC-RPGVEGPRCDTC--RSGFYSFPICQACWCSALGSYQM 546

Query: 1166 TFS 1168
              S
Sbjct: 547  PCS 549



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 9/84 (10%)

Query: 245 YSFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEAC--------DIPHCTDNCGFPH 295
           YSF +C    CS  G  ++  SS T +CEC     G+ C        D PHC  +     
Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587

Query: 296 RGICNSSDVRGCSCFSDWQGPGCS 319
                +S++  C C    +GP CS
Sbjct: 588 PAGTINSNLGYCQCKLHVEGPTCS 611



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 50/220 (22%), Positives = 70/220 (31%), Gaps = 46/220 (20%)

Query: 915  GSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCM 974
            G  C    N   +QC       T C     G   C  CS  ++  +          GQC 
Sbjct: 1282 GGQCPCQPNVIGRQC-------TRCATGHYGFPRCKPCSCGRRLCEEMT-------GQCR 1327

Query: 975  EWYTMSTCPPENCSGYCTC--SHCLE---QPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029
                   CPP      C    +H        GC  C    N  +   IE +      MP 
Sbjct: 1328 -------CPPRTVRPQCEVCETHSFSFHPMAGCEGC----NCSRRGTIEAA------MPE 1370

Query: 1030 -QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEK------CEN 1082
                +G    +P +    C   +   + F  C  C CN         +C+       C+ 
Sbjct: 1371 CDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT--EPGVCDPGTGACLCKE 1428

Query: 1083 LTTGKHCETCISG-FYGDPTNGGKCQPCKCNGHASLCNTN 1121
               G  C  C  G F+ DP N   C  C C G  + C+++
Sbjct: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSS 1468



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 10/59 (16%)

Query: 101  CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFVTDGPGNYKYKTKC 158
            C+R     G C+PGTG C+C     G +C  C  G F L          P N K  T C
Sbjct: 1407 CNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL---------DPANLKGCTSC 1456



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 5/45 (11%)

Query: 100  ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGF 144
            EC      G  C+P  GQC C    +G QC  C      TG  GF
Sbjct: 1267 ECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA-----TGHYGF 1306



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 1/31 (3%)

Query: 103  RPCVNGGR-CNPGTGQCVCPAGWVGEQCQHC 132
            +PC  G R C   TGQC CP   V  QC+ C
Sbjct: 1310 KPCSCGRRLCEEMTGQCRCPPRTVRPQCEVC 1340



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%)

Query: 254 CSGRGE-CKISNSSDTVECECSENWKGEACD 283
           C+G  E C I+N      CEC  +  GE CD
Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCD 331



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%)

Query: 89   AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132
            AV GS  A    C  P  N    G   N G  +C C AG+ G QC+ C
Sbjct: 1726 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769


>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
          Length = 1724

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%)

Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114
            C  C CNGHS +C + S IC  C++ T G+HCE C  G+YG+  + G C+ C C   N  
Sbjct: 75   CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 133

Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155
            A+ C  N G   C+ K G  G +C+ C     Y GNP +  G+C
Sbjct: 134  ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 175



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%)

Query: 982  CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037
            C P NC+G+   + C  Q G G C +  +   G    +C EG Y   V    +A      
Sbjct: 75   CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 125

Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096
            P P  NS                  C  NG   +C        C+   TG  CE C  G+
Sbjct: 126  PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 164

Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140
            +G+P   GG CQPC CN +  L  C+  TG C       ++   + D+C  C
Sbjct: 165  FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 216



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 1092 CISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGN 1149
            C  G+Y D      G+C PC CNGH++ C   +G C        G+ C+ C  +  Y GN
Sbjct: 59   CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC--QEGYYGN 116

Query: 1150 PLRGTC 1155
             + G+C
Sbjct: 117  AVHGSC 122



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%)

Query: 89  AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132
           AV GS  A    C  P  N    G   N G  +C C AG+ G QC+ C
Sbjct: 117 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 160


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 40/98 (40%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 1060 CPACQCNGHSK-CINQSICEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGHAS 1116
            C  C CNGHS+ C  ++    C + T G HCE C  G+YGD T G    CQPC C G +S
Sbjct: 721  CVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSS 780

Query: 1117 LCNT-NTGKCFCTT--KGVKGDECQLCEVENRYQGNPL 1151
                  T +  CT    G  G  C+LC  ++ Y G+PL
Sbjct: 781  CAVVPKTKEVVCTNCPTGTTGKRCELC--DDGYFGDPL 816



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 36/106 (33%), Positives = 48/106 (45%), Gaps = 16/106 (15%)

Query: 1060 CPACQCNGHSKCI-----NQSICEKCENLTTGKHCETCISGFYGDP--TNG--GKCQPCK 1110
            C  C C G S C       + +C  C   TTGK CE C  G++GDP   NG    C+ C+
Sbjct: 770  CQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQ 829

Query: 1111 CNGH-----ASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPL 1151
            C+ +        CN  TG+C        G  C  C  ++ + GNPL
Sbjct: 830  CSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRC--KDGFFGNPL 873



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 27/163 (16%)

Query: 991  CTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLED 1050
            C CS  ++    G C    N   G+C++  Y        +   G F+  PL  +      
Sbjct: 828  CQCSDNIDPNAVGNC----NRLTGECLKCIYNTAGFYCDRCKDG-FFGNPLAPNPAD--- 879

Query: 1051 SRYNWSFIHCPACQCNGHSKCINQSICE----KCENL--TTGKHCETCISGFYGDPTNGG 1104
                     C AC CN +     QS C     +CE L   TG+ C  C  GFY +  +G 
Sbjct: 880  --------KCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFY-NLQSGQ 930

Query: 1105 KCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLCEVEN 1144
             C+ C C+   S    C+  TG+C C   G+ G  C+ CEV +
Sbjct: 931  GCERCDCHALGSTNGQCDIRTGQCEC-QPGITGQHCERCEVNH 972



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 55/193 (28%), Positives = 70/193 (36%), Gaps = 36/193 (18%)

Query: 981  TCPPENCSGYCTCSHCLEQPGCGWCTD----PSNTGKGK------CIEGSYKGPVKMPSQ 1030
            TC PE  +G C C      P C  C+D     S  G         C  GS    V    +
Sbjct: 732  TCDPE--TGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKE 789

Query: 1031 APTGNFYPQPLLNSSMCLEDSRY-------NWSFIHCPACQC------NGHSKCINQS-I 1076
                N  P         L D  Y       N     C  CQC      N    C   +  
Sbjct: 790  VVCTNC-PTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGE 848

Query: 1077 CEKCENLTTGKHCETCISGFYGD---PTNGGKCQPCKCNGHASL-----CNTNTGKCFCT 1128
            C KC   T G +C+ C  GF+G+   P    KC+ C CN + ++     CN  TG+C C 
Sbjct: 849  CLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECL 908

Query: 1129 TKGVKGDECQLCE 1141
               V G +C  C+
Sbjct: 909  PH-VTGQDCGACD 920



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 1086 GKHCETCISGFYGDPTNGGKCQP---CKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142
            G+ CE C+SG+  +  N G   P   C CNGH+  C+  TG C C      G  C+ C  
Sbjct: 698  GQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNC-RDNTAGPHCEKC-- 754

Query: 1143 ENRYQGNPLRGT 1154
             + Y G+   GT
Sbjct: 755  SDGYYGDSTAGT 766



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 15/95 (15%)

Query: 1060 CPACQCNGHSK-CI----------NQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQP 1108
            C  C CNG S+ C           +   C  C++ T G HCE C   F+    N   C  
Sbjct: 339  CLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFF-RLGNNEACSS 397

Query: 1109 CKCNGHASLCN--TNTGKCFCTTKGVKGDECQLCE 1141
            C C+   SL     + G+C C   GV GD+C  C+
Sbjct: 398  CHCSPVGSLSTQCDSYGRCSC-KPGVMGDKCDRCQ 431



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 55/244 (22%), Positives = 83/244 (34%), Gaps = 77/244 (31%)

Query: 900  STRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCV 959
            +T G+    C+   N     R    SA +C  PC       DC   S EC +        
Sbjct: 310  NTYGVDCEKCLPFFNDRPWRRATAESASEC-LPC-------DCNGRSQECYF-------- 353

Query: 960  DSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEG 1019
            D   Y ++   G C            NC      +HC                  +C E 
Sbjct: 354  DPELYRSTGHGGHCT-----------NCQDNTDGAHC-----------------ERCREN 385

Query: 1020 SYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEK 1079
             ++                  L N+  C   S  + S +   + QC+ + +C        
Sbjct: 386  FFR------------------LGNNEAC---SSCHCSPVGSLSTQCDSYGRC-------S 417

Query: 1080 CENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASL--CNTNTGKCFCTTKGVKGDEC 1137
            C+    G  C+ C  GF+     G  C+PC C+   S+  CN  TG+C C    V+G  C
Sbjct: 418  CKPGVMGDKCDRCQPGFHSLTEAG--CRPCSCDPSGSIDECNIETGRCVC-KDNVEGFNC 474

Query: 1138 QLCE 1141
            + C+
Sbjct: 475  ERCK 478



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 11/89 (12%)

Query: 1060 CPACQCNG----HSKC-INQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCN-- 1112
            C  C C+     + +C I    CE C+   TG+HCE C    +G    G  C+PC C+  
Sbjct: 932  CERCDCHALGSTNGQCDIRTGQCE-CQPGITGQHCERCEVNHFGFGPEG--CKPCDCHPE 988

Query: 1113 GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141
            G  SL   + G+C C  +G  G+ C  CE
Sbjct: 989  GSLSLQCKDDGRCEC-REGFVGNRCDQCE 1016



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 24/116 (20%)

Query: 1063 CQCNGH-SKCINQS----ICEKCENLTTGKHCETCISGFYGDP------TNGGKCQPCKC 1111
            C+CNGH S+C+       +C  C++ T G  CE C+  F   P       +  +C PC C
Sbjct: 286  CKCNGHASECMKNEFDKLVCN-CKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC 344

Query: 1112 NGHASLC---------NTNTGKCFCTTKGVKGDECQLCEVEN--RYQGNPLRGTCY 1156
            NG +  C           + G C        G  C+ C  EN  R   N    +C+
Sbjct: 345  NGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCR-ENFFRLGNNEACSSCH 399



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 13/36 (36%), Positives = 18/36 (50%)

Query: 97  EAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
           E  +C       G+C+  TGQC C  G  G+ C+ C
Sbjct: 933 ERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERC 968


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 77/267 (28%), Positives = 105/267 (39%), Gaps = 51/267 (19%)

Query: 915  GSVCERPANHSAKQCRTPCALRTACGDCTSGSSE-----CMWCSNMKQCVDSNAYVASFP 969
            GS C R       QC+ P  +   C  C++GS +     C  C    Q   S   V    
Sbjct: 778  GSSCSRLGGQC--QCK-PLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQ--GSKDTVCDQV 832

Query: 970  FGQCMEWYTMSTCPPENC-SGY--------CTCSHCLE--QPGCGWCTDPSN--TGKG-- 1014
             GQC     +S    + C +GY        C C+   E   P  G C +     TG+   
Sbjct: 833  TGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCE 892

Query: 1015 KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQ 1074
            +CI+G Y  P       P             +C +D   N  F H  +C  N  S  +  
Sbjct: 893  RCIDGYYGNPSSGQPCRPC------------LCPDDPSSNQYFAH--SCYQNLWSSDV-- 936

Query: 1075 SICEKCENLTTGKHCETCISGFYGDPT-NGGKCQPCKCNGHASL-----CNTNTGKCFCT 1128
             IC  C    TG  C  C +GFYG+P  +G  CQPC CN +  +     C+  TG+C   
Sbjct: 937  -ICN-CLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRC 994

Query: 1129 TKGVKGDECQLCEVENRYQGNPLRGTC 1155
                +G  CQLC  +  + G+ L  TC
Sbjct: 995  LHNTQGANCQLC--KPGHYGSALNQTC 1019



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 59/232 (25%), Positives = 87/232 (37%), Gaps = 45/232 (19%)

Query: 937  TACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS---GYCT- 992
            T CG+C++G                N  ++  P   C     +    PE+CS   G C  
Sbjct: 947  TQCGECSTGFY-------------GNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993

Query: 993  CSHCLEQPGCGWCTDPSNTGKG---KCIEGSYKGPVKMPSQAPTGN--FYPQPLLNSSMC 1047
            C H  +   C  C  P + G      C   S       P + P G       P+  +  C
Sbjct: 994  CLHNTQGANCQLCK-PGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052

Query: 1048 LED---------SRYNWSFIHCPACQ-CNGHSKCINQSICEK------CENLTTGKHCET 1091
            L +         +   W+ +    CQ C+   +    S C++      C+    GK C  
Sbjct: 1053 LPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE 1112

Query: 1092 CISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKGVKGDECQLC 1140
            C   +YGDP   G+C PC CN   +   +C+ +TG C C  +GV G  C  C
Sbjct: 1113 CQENYYGDPP--GRCIPCDCNRAGTQKPICDPDTGMCRC-REGVSGQRCDRC 1161



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 44/188 (23%), Positives = 72/188 (38%), Gaps = 65/188 (34%)

Query: 983  PPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLL 1042
            PP    G C C H  + P C  C D                            F+     
Sbjct: 287  PPGMVHGQCVCQHNTDGPNCERCKD----------------------------FFQDAPW 318

Query: 1043 NSSMCLEDSRYNWSFIHCPACQCNGHS-KC------------INQSICEKCENLTTGKHC 1089
              +  L+D+        C +C CN HS +C            ++  +CE C++ T G+HC
Sbjct: 319  RPAADLQDNA-------CRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHC 371

Query: 1090 ETCISGFYGDP----TNGGKCQPCKCNGHAS----LCNTNT--------GKCFCTTKGVK 1133
            + C   FY DP    ++   C PC+C+   +    +C +++        G+C C  + V+
Sbjct: 372  DRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLC-KENVE 430

Query: 1134 GDECQLCE 1141
            G +C  C+
Sbjct: 431  GAKCDQCK 438



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 1060 CPACQCNGHSKC------INQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCN- 1112
            C  C CN           ++   C  C +  TG HCE C  G++G   +   C PC C+ 
Sbjct: 452  CQPCDCNPLGSLPFLTCDVDTGQC-LCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDI 510

Query: 1113 --GHASLCNTNTGKCFCTTKGVKGDEC 1137
               ++++C+   G+C C    V G  C
Sbjct: 511  GGAYSNVCSPKNGQCECRPH-VTGRSC 536



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 100  ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
            +CD        C+  TGQC C  G+ G++C  C
Sbjct: 1081 DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 100  ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
            +C+R       C+P TG C C  G  G++C  C
Sbjct: 1129 DCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 27/167 (16%)

Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWV----GEQCQHCGGRFRLTGSSGFVT--DGPGNYKY 154
           C   CVN      G+  C C  G+V       C+      ++   SG +T  + P  Y  
Sbjct: 741 CQHECVN----TMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPS 796

Query: 155 KTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPER 210
           + +CTW I   P   ++L F+ F  E    C++DHL V+DG++  +P++    G  +P+ 
Sbjct: 797 RKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPD- 855

Query: 211 DGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGR 257
                   +VAT     + F SDA+    GF  T+S       C GR
Sbjct: 856 -------PLVATGNKMFVRFVSDASVQRKGFQATHS-----TECGGR 890



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 46/167 (27%), Positives = 67/167 (40%), Gaps = 15/167 (8%)

Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLY 187
           CGG  R         + P +Y+   +C W I    +  + L F  F  E    C++D+L 
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521

Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF--NITY 245
           V DG S  +PL+  F G   PE        ++ +TS    + F SD   N  GF  N   
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPE--------DIRSTSNTLWMKFVSDGTVNKAGFAANFFK 573

Query: 246 SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
             D C     G  E +  N+  + +C C   ++    D   C   CG
Sbjct: 574 EEDECAKPDRGGCEQRCLNTLGSYQCACEPGYE-LGPDRRSCEAACG 619



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 34/131 (25%), Positives = 51/131 (38%), Gaps = 16/131 (12%)

Query: 123  GWVGEQCQHCGGRFRLTGSS----GFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFA 178
            G+       CGGR +              G  NY  +  C WL+  +    + L F  F 
Sbjct: 878  GFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFE 937

Query: 179  TE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDA 234
             E    C +D++ ++DG    A  +  F G   PE        E+ +     L+HF +D 
Sbjct: 938  VEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPE--------EIYSIGDSVLIHFHTDD 989

Query: 235  AYNLTGFNITY 245
              N  GF+I Y
Sbjct: 990  TINKKGFHIRY 1000



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 49/189 (25%), Positives = 76/189 (40%), Gaps = 34/189 (17%)

Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWV----GEQCQH-CGGRFRLTGSSGFVTDG--PGNYK 153
           C++ C+N      G+ QC C  G+        C+  CGG   LT  +G +T    P  Y 
Sbjct: 586 CEQRCLN----TLGSYQCACEPGYELGPDRRSCEAACGGL--LTKLNGTITTPGWPKEYP 639

Query: 154 YKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPE 209
               C W +       + ++F  F  E    C +D++ ++ G S  + L   F G  VPE
Sbjct: 640 PNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPE 699

Query: 210 RDGNETVPEVVATSGY--ALLHFFSDAAYNLTGFNITYSFDMCPNNCS-GRGEC--KISN 264
                     V TS +    + F SD   +  GF   +  D   + CS   G C  +  N
Sbjct: 700 ----------VITSQFNNMRIEFKSDNTVSKKGFKAHFFSD--KDECSKDNGGCQHECVN 747

Query: 265 SSDTVECEC 273
           +  +  C+C
Sbjct: 748 TMGSYMCQC 756



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 13/94 (13%)

Query: 120 CPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFN---- 175
           CPA   GE  Q   G      S GF    P  Y   T C W +   P   + L F     
Sbjct: 346 CPA--CGETLQESNGNL---SSPGF----PNGYPSYTHCIWRVSVTPGEKIVLNFTTMDL 396

Query: 176 HFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPE 209
           + ++ C +D++ V DG    +PL+  F G  +PE
Sbjct: 397 YKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPE 430


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 29/195 (14%)

Query: 101 CDRPCVNGGRCNPGTGQCVCPAG-WV---GEQCQHCGGRFRLTGSSGFVT--DGPGNYKY 154
           C   CVN      G+  C C  G W+   G  C+  G   +++   G +   + P  Y  
Sbjct: 743 CQHECVN----TFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPS 798

Query: 155 KTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPER 210
           + +CTW I       ++L FN F  E    C++DHL +YDG    AP++  F G   P+ 
Sbjct: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPD- 857

Query: 211 DGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVE 270
                    VA+     L F+SDA+    GF   +S       C GR + ++        
Sbjct: 858 -------PTVASGSSMFLRFYSDASVQRKGFQAVHS-----TECGGRLKAEVQTKELYSH 905

Query: 271 CECSE-NWKGEA-CD 283
            +  + N+  EA CD
Sbjct: 906 AQFGDNNYPSEARCD 920



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 44/167 (26%), Positives = 66/167 (39%), Gaps = 15/167 (8%)

Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLY 187
           CGG            + P +Y+   +C W I       + L F  F  E    C++D+L 
Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523

Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF--NITY 245
           V DG +  + L+  F G   PE        +V ++S    + F SD + N  GF  N   
Sbjct: 524 VRDGPTEESALIGHFCGYEKPE--------DVKSSSNRLWMKFVSDGSINKAGFAANFFK 575

Query: 246 SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
             D C     G  E +  N+  + +C C   ++  A D   C   CG
Sbjct: 576 EVDECSWPDHGGCEHRCVNTLGSYKCACDPGYE-LAADKKMCEVACG 621



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 16/132 (12%)

Query: 123  GWVGEQCQHCGGRFRLTGSS----GFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFA 178
            G+       CGGR +    +         G  NY  + +C W+I  +    + L F  F 
Sbjct: 880  GFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFE 939

Query: 179  TE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDA 234
             E    C +D++  YDG    AP +  F         G+  + E+ +     ++ F +D 
Sbjct: 940  VEEEADCGYDYMEAYDGYDSSAPRLGRFC--------GSGPLEEIYSAGDSLMIRFRTDD 991

Query: 235  AYNLTGFNITYS 246
              N  GF+  Y+
Sbjct: 992  TINKKGFHARYT 1003



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 13/94 (13%)

Query: 120 CPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHF-- 177
           CPA   GE  Q   G F   G        P  Y   + C W I   P   + L F     
Sbjct: 348 CPA--CGETLQDTTGNFSAPGF-------PNGYPSYSHCVWRISVTPGEKIVLNFTSMDL 398

Query: 178 --ATECSWDHLYVYDGDSIYAPLVAAFSGLIVPE 209
             +  C +D++ V DG    APL+  F G  +PE
Sbjct: 399 FKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPE 432


>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
          Length = 3487

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 12/116 (10%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
           CGG   LT  SG +     PG YK    C W+IE QP   +++ F+ F TE ++D L V 
Sbjct: 752 CGGH--LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809

Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
           DG +  APL+  + G  VP+         +++TS Y  L F +D +++  GF + Y
Sbjct: 810 DGRTYSAPLIGVYHGTQVPQ--------FLISTSNYLYLLFSTDKSHSDIGFQLRY 857



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 11/123 (8%)

Query: 131  HCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188
            HC     LT S+G +     PG+Y     C+WL+  +P+  + L   +F +E  +D   +
Sbjct: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413

Query: 189  YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNITYSF 247
            +DG S  +PL+ A S        GN + P +V +S  ++ L + SD AYN  GF I YS 
Sbjct: 2414 FDGPSGQSPLLKALS--------GNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465

Query: 248  DMC 250
              C
Sbjct: 2466 PYC 2468



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 22/136 (16%)

Query: 113  PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIM 170
            P    C+ P          CGG   LTG SG +     P  Y    +C W +   P+ ++
Sbjct: 1436 PSPPTCIAP----------CGGD--LTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483

Query: 171  RLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHF 230
             L FN F  E  +D L++YDG    +PL+ +F G  +P R        + ++S    L F
Sbjct: 1484 ALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGR--------IESSSNSLFLAF 1535

Query: 231  FSDAAYNLTGFNITYS 246
             SDA+ +  GF I Y+
Sbjct: 1536 RSDASVSNAGFVIDYT 1551



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 15/123 (12%)

Query: 136 FRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDS 193
           F  T  SG V     P +Y     C WLI  +P   + L FN    E  +D L + DG +
Sbjct: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGAT 639

Query: 194 IYAPLVAAFSGLIVPERDGNETVPEVVATSGY-ALLHFFSDAAYNLTGFNITYS---FDM 249
             AP++  FSG           +P  + +SG+ A L F +D +    GFNIT++    + 
Sbjct: 640 AEAPVLGTFSG---------NQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNE 690

Query: 250 CPN 252
           CP+
Sbjct: 691 CPD 693



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 42/158 (26%), Positives = 64/158 (40%), Gaps = 16/158 (10%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       +      P  Y     C W I       ++++   F TE +WD L V+DG
Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDG 1855

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY---SFD 248
                  ++ +FSG  VP          + +TS    LHF+SD + +  GF++ Y      
Sbjct: 1856 ADNTVTMLGSFSGTTVPAL--------LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907

Query: 249  MC-----PNNCSGRGECKISNSSDTVECECSENWKGEA 281
             C     P+N    GE  + N   + +CE     +G A
Sbjct: 1908 SCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHA 1945



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 17/159 (10%)

Query: 132  CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190
            CGG  R   S   ++ G P  Y++   C W IE +    + L F  F TE   D L ++D
Sbjct: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWD 1330

Query: 191  GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250
            G           SG+++ E  G     ++ +T    +L F +D   +  GF I +S    
Sbjct: 1331 G--------PVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTA 1382

Query: 251  --------PNNCSGRGECKISNSSDTVECECSENWKGEA 281
                    P N S  G+   +  S   +C+     +G A
Sbjct: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSA 1421



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 16/130 (12%)

Query: 130 QHCGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHL 186
           Q+C   F+L G +G V + PG    Y     CTW I  +    ++L F  FA E  +D L
Sbjct: 24  QNC--TFQLHGPNGTV-ESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVL 80

Query: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS 246
            V+DG      L    +G  +P          +V+ +    L   SD A +  GF+ TY 
Sbjct: 81  SVFDGPPQPENLRTRLTGFQLP--------ATIVSAATTLSLRLISDYAVSAQGFHATY- 131

Query: 247 FDMCPNNCSG 256
            ++ P++  G
Sbjct: 132 -EVLPSHTCG 140



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 26/143 (18%)

Query: 111  CNPGTGQ--------CVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLI 162
            C PGT +        C+   G   E+ +       +  S GF    PGNY     C+W I
Sbjct: 1949 CMPGTVRRWNYPPPLCIAQCGGTVEEMEG------VILSPGF----PGNYPSNMDCSWKI 1998

Query: 163  EGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVAT 222
                     ++F +F+TE + D++ + +G    + ++  FSG  +P          +++T
Sbjct: 1999 ALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPS--------SLLST 2050

Query: 223  SGYALLHFFSDAAYNLTGFNITY 245
            S    ++F SD + N  GF + Y
Sbjct: 2051 SHETTVYFHSDHSQNRPGFKLEY 2073



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 49/178 (27%), Positives = 68/178 (38%), Gaps = 23/178 (12%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV- 188
           CGG  R  G SG ++    P  Y     CTW I  +    + L F  F  E  +D L V 
Sbjct: 202 CGGTLR--GQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259

Query: 189 -YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSF 247
             +G S++      F+G  +P          V+++  +  LHF SD  +   GF+  Y  
Sbjct: 260 GTEGSSLW------FTGASLP--------APVISSKNWLRLHFTSDGNHRQRGFSAQYQV 305

Query: 248 DMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVR 305
                    RG  K+  S D  +        G +     C D  G P RG    SD R
Sbjct: 306 KK-QIELKSRG-VKLMPSKDNSQKTSVLTQVGVSQGHNMCPDP-GIPERGKRLGSDFR 360



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 19/127 (14%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG  +  GSSG +     P  Y     CTW+IE    + +   F+ F  E   D+L + 
Sbjct: 924  CGGFIQ--GSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLIT 981

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGY----ALLHFFSDAAYNLTGFNITY 245
            +  S   PL           +     +P  ++   Y    A + F SD + +  GFNIT+
Sbjct: 982  ENGSFTQPL----------RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITF 1031

Query: 246  S-FDMCP 251
            S +D+ P
Sbjct: 1032 SEYDLEP 1038



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 48/188 (25%), Positives = 66/188 (35%), Gaps = 39/188 (20%)

Query: 92   GSAAAEAKECDRP------CVNGGRCNPG---TGQCVCPAGWVGEQ---CQH-------- 131
            G  A E +EC  P       V G   N G   T +C+      G     CQH        
Sbjct: 2114 GCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDH 2173

Query: 132  --------CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSW 183
                    CGG    +  + +    P  Y     C WLI       +RL  +   TE S 
Sbjct: 2174 PLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG 2233

Query: 184  DHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI 243
            D + ++DG    AP +  F+  +  +         V ++S   LL F  DAA   TG   
Sbjct: 2234 DFITIWDGPQQTAPRLGVFTRSMAKK--------TVQSSSNQVLLKFHRDAA---TGGIF 2282

Query: 244  TYSFDMCP 251
              +F   P
Sbjct: 2283 AIAFSAYP 2290



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 46/178 (25%), Positives = 66/178 (37%), Gaps = 16/178 (8%)

Query: 76   LLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAG----WVGE--QC 129
            L PCE     A +   G            C  G R   GT +  C  G    W     +C
Sbjct: 1036 LEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLE-GTARITCLGGRRRLWSSPLPRC 1094

Query: 130  -QHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188
               CG     T  +    + P NY    +C + I+ QP + ++L+   F      D L V
Sbjct: 1095 VAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELS-EGDVLKV 1153

Query: 189  YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS 246
            YDG++  A L+  FS               + +TS    L F +DA     GF + +S
Sbjct: 1154 YDGNNNSARLLGVFS-------HSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFS 1204


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 69/264 (26%), Positives = 97/264 (36%), Gaps = 48/264 (18%)

Query: 928  QCRTPCALRTACGDCTSGSSECMWCSNMKQC--VDSNAYVASFPFGQCMEWYTMSTCPPE 985
            QC    ++   C    SG  EC   +   QC     N Y       +  +  T  + P  
Sbjct: 748  QCNLHGSVNKFCNP-HSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806

Query: 986  NCS---GYCTCSHCLEQPGCGWCTD--------------PSNTGKGKCIEGSYKGPVKMP 1028
             C+   G C C   +E   C  C +              P N  K   I GS     K  
Sbjct: 807  VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN-KST 865

Query: 1029 SQAP-----TGNFYPQPLLNSSMCLEDSRYNWS---FIHCPACQCNGHSKCINQSICEK- 1079
             Q P     TG       L  + C E  RYN +   F HC  C+C+     +  +IC+  
Sbjct: 866  GQCPCKLGVTG-------LRCNQC-EPHRYNLTIDNFQHCQMCECDSLGT-LPGTICDPI 916

Query: 1080 -----CENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKG 1131
                 C     G+ C  C  GFY  P N   C PC C+   +   +CN+ TG+C C    
Sbjct: 917  SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976

Query: 1132 VKGDECQLCEVENRYQGNPLRGTC 1155
            + G  C  C+ ++ +  +P  G C
Sbjct: 977  IAGQRCDQCK-DHYFGFDPQTGRC 999



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 66/254 (25%), Positives = 96/254 (37%), Gaps = 42/254 (16%)

Query: 909  CINPLNGSVCERPANHSAKQCRTPCALRTACGDC---TSGSSE-CMWCSNMKQCVDSNAY 964
            C +   G  CE   ++  +Q     +    C  C   T G+    + C  +    +   +
Sbjct: 608  CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667

Query: 965  VASFPFGQCME-WYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKG 1023
            V+     QC   +Y +    P+ CS  C C+      G   C    N+G+ KC + +  G
Sbjct: 668  VSGRQCNQCQNGFYNLQELDPDGCSP-CNCNTSGTVDGDITCHQ--NSGQCKC-KANVIG 723

Query: 1024 PVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSF--IHCPACQCNGHSK----CINQSIC 1077
                              L    C    ++  SF  + C  CQCN H      C   S  
Sbjct: 724  ------------------LRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765

Query: 1078 EKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASL----CNTNTGKCFCTTKGV 1132
             +C+    G  C+TC   FYG D TN   C+ C C+   SL    CN  TG+C C    V
Sbjct: 766  CECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGTVCNAKTGQCIC-KPNV 821

Query: 1133 KGDECQLCEVENRY 1146
            +G +C  C   N Y
Sbjct: 822  EGRQCNKCLEGNFY 835



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 26/108 (24%)

Query: 1059 HCPACQCNGHSKCINQSI----------------CEKCENLTTGKHCETCISGFY----G 1098
            +C  CQCN HSK  + +I                C+ CE+ TTG++CE C   F+     
Sbjct: 571  NCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630

Query: 1099 DPTNGGKCQPCKCN-----GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141
            DP+    C+PC C+       + LC+   G+C C  + V G +C  C+
Sbjct: 631  DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNC-KRHVSGRQCNQCQ 677



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 58/236 (24%), Positives = 85/236 (36%), Gaps = 63/236 (26%)

Query: 913  LNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQ 972
            +NGS+     N S  QC  PC L             C  C   +     N  + +F   Q
Sbjct: 855  INGSLL---CNKSTGQC--PCKLGVT-------GLRCNQCEPHRY----NLTIDNFQHCQ 898

Query: 973  CMEWYTMSTCPPENC---SGYCTCSHCLEQPGCGWCTDPSNTGK--GKCIEGSYKGPVKM 1027
              E  ++ T P   C   SG C C              P+  G+   +C  G Y  P   
Sbjct: 899  MCECDSLGTLPGTICDPISGQCLCV-------------PNRQGRRCNQCQPGFYISPG-- 943

Query: 1028 PSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGK 1087
                           N++ CL  S +    ++       G   C + SI         G+
Sbjct: 944  ---------------NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA--------GQ 980

Query: 1088 HCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLC 1140
             C+ C   ++G     G+CQPC C+   +L   C+  TG+CFC  + V G +C  C
Sbjct: 981  RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFC-KQFVTGSKCDAC 1035



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 25/104 (24%)

Query: 1063 CQCNGHS-KCINQSICEKC----ENLTTGKHCETCISGFYGDPTNGG------KCQPCKC 1111
            CQC+GH+  C   S   +C    E+ T G HC+ C+  +   P   G       C+PC+C
Sbjct: 518  CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577

Query: 1112 NGHASLCNTNT--------------GKCFCTTKGVKGDECQLCE 1141
            N H+  C+ N               G C        G  C+LC+
Sbjct: 578  NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCK 621



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 13/136 (9%)

Query: 224 GYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECE-CSENWKGEAC 282
           G+  L  F+D        N+  S +   N  SG+ ECK    +  ++C+ C EN+ G   
Sbjct: 732 GFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK--KEAKGLQCDTCRENFYG--L 787

Query: 283 DIPHC----TDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338
           D+ +C     D  G     +CN+   + C C  + +G  C+  +  N  F+ R+  S L 
Sbjct: 788 DVTNCKACDCDTAGSLPGTVCNAKTGQ-CICKPNVEGRQCNKCLEGN--FYLRQNNSFLC 844

Query: 339 LP-RASHKAVVNGNIM 353
           LP        +NG+++
Sbjct: 845 LPCNCDKTGTINGSLL 860



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 62/239 (25%), Positives = 89/239 (37%), Gaps = 53/239 (22%)

Query: 97   EAKECDRP-CVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFV-----TDGP 149
            +A +CD    + G  CN  TGQC+C     G QC  C  G F L  ++ F+      D  
Sbjct: 793  KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852

Query: 150  GNYKYKTKCTWLIEGQPNR--IMRLRFN------HFATECSWDHLYVYDGDS---IYAPL 198
            G       C       P +  +  LR N      +  T  ++ H  + + DS   +   +
Sbjct: 853  GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912

Query: 199  VAAFSG--LIVPERDG---NETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNN 253
                SG  L VP R G   N+  P    + G            N TG          P +
Sbjct: 913  CDPISGQCLCVPNRQGRRCNQCQPGFYISPG------------NATG--------CLPCS 952

Query: 254  CSGRGECKISNSSDTVECECSE-NWKGEACDIPHCTDN-CGF-PHRGICNSSDVRGCSC 309
            C   G      +S T +C C + +  G+ CD   C D+  GF P  G C     + C+C
Sbjct: 953  CHTTGAVNHICNSLTGQCVCQDASIAGQRCD--QCKDHYFGFDPQTGRC-----QPCNC 1004



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 12/31 (38%), Positives = 17/31 (54%)

Query: 111 CNPGTGQCVCPAGWVGEQCQHCGGRFRLTGS 141
           C+  +GQC C A  +G +C HC   F+   S
Sbjct: 708 CHQNSGQCKCKANVIGLRCDHCNFGFKFLRS 738


>gi|219842259 usherin isoform A [Homo sapiens]
          Length = 1546

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 69/264 (26%), Positives = 97/264 (36%), Gaps = 48/264 (18%)

Query: 928  QCRTPCALRTACGDCTSGSSECMWCSNMKQC--VDSNAYVASFPFGQCMEWYTMSTCPPE 985
            QC    ++   C    SG  EC   +   QC     N Y       +  +  T  + P  
Sbjct: 748  QCNLHGSVNKFCNP-HSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806

Query: 986  NCS---GYCTCSHCLEQPGCGWCTD--------------PSNTGKGKCIEGSYKGPVKMP 1028
             C+   G C C   +E   C  C +              P N  K   I GS     K  
Sbjct: 807  VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN-KST 865

Query: 1029 SQAP-----TGNFYPQPLLNSSMCLEDSRYNWS---FIHCPACQCNGHSKCINQSICEK- 1079
             Q P     TG       L  + C E  RYN +   F HC  C+C+     +  +IC+  
Sbjct: 866  GQCPCKLGVTG-------LRCNQC-EPHRYNLTIDNFQHCQMCECDSLGT-LPGTICDPI 916

Query: 1080 -----CENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKG 1131
                 C     G+ C  C  GFY  P N   C PC C+   +   +CN+ TG+C C    
Sbjct: 917  SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976

Query: 1132 VKGDECQLCEVENRYQGNPLRGTC 1155
            + G  C  C+ ++ +  +P  G C
Sbjct: 977  IAGQRCDQCK-DHYFGFDPQTGRC 999



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 66/254 (25%), Positives = 96/254 (37%), Gaps = 42/254 (16%)

Query: 909  CINPLNGSVCERPANHSAKQCRTPCALRTACGDC---TSGSSE-CMWCSNMKQCVDSNAY 964
            C +   G  CE   ++  +Q     +    C  C   T G+    + C  +    +   +
Sbjct: 608  CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667

Query: 965  VASFPFGQCME-WYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKG 1023
            V+     QC   +Y +    P+ CS  C C+      G   C    N+G+ KC + +  G
Sbjct: 668  VSGRQCNQCQNGFYNLQELDPDGCSP-CNCNTSGTVDGDITCHQ--NSGQCKC-KANVIG 723

Query: 1024 PVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSF--IHCPACQCNGHSK----CINQSIC 1077
                              L    C    ++  SF  + C  CQCN H      C   S  
Sbjct: 724  ------------------LRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765

Query: 1078 EKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASL----CNTNTGKCFCTTKGV 1132
             +C+    G  C+TC   FYG D TN   C+ C C+   SL    CN  TG+C C    V
Sbjct: 766  CECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGTVCNAKTGQCIC-KPNV 821

Query: 1133 KGDECQLCEVENRY 1146
            +G +C  C   N Y
Sbjct: 822  EGRQCNKCLEGNFY 835



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 26/108 (24%)

Query: 1059 HCPACQCNGHSKCINQSI----------------CEKCENLTTGKHCETCISGFY----G 1098
            +C  CQCN HSK  + +I                C+ CE+ TTG++CE C   F+     
Sbjct: 571  NCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630

Query: 1099 DPTNGGKCQPCKCN-----GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141
            DP+    C+PC C+       + LC+   G+C C  + V G +C  C+
Sbjct: 631  DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNC-KRHVSGRQCNQCQ 677



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 58/236 (24%), Positives = 85/236 (36%), Gaps = 63/236 (26%)

Query: 913  LNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQ 972
            +NGS+     N S  QC  PC L             C  C   +     N  + +F   Q
Sbjct: 855  INGSLL---CNKSTGQC--PCKLGVT-------GLRCNQCEPHRY----NLTIDNFQHCQ 898

Query: 973  CMEWYTMSTCPPENC---SGYCTCSHCLEQPGCGWCTDPSNTGK--GKCIEGSYKGPVKM 1027
              E  ++ T P   C   SG C C              P+  G+   +C  G Y  P   
Sbjct: 899  MCECDSLGTLPGTICDPISGQCLCV-------------PNRQGRRCNQCQPGFYISPG-- 943

Query: 1028 PSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGK 1087
                           N++ CL  S +    ++       G   C + SI         G+
Sbjct: 944  ---------------NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA--------GQ 980

Query: 1088 HCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLC 1140
             C+ C   ++G     G+CQPC C+   +L   C+  TG+CFC  + V G +C  C
Sbjct: 981  RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFC-KQFVTGSKCDAC 1035



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 25/104 (24%)

Query: 1063 CQCNGHS-KCINQSICEKC----ENLTTGKHCETCISGFYGDPTNGG------KCQPCKC 1111
            CQC+GH+  C   S   +C    E+ T G HC+ C+  +   P   G       C+PC+C
Sbjct: 518  CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577

Query: 1112 NGHASLCNTNT--------------GKCFCTTKGVKGDECQLCE 1141
            N H+  C+ N               G C        G  C+LC+
Sbjct: 578  NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCK 621



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 13/136 (9%)

Query: 224 GYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECE-CSENWKGEAC 282
           G+  L  F+D        N+  S +   N  SG+ ECK    +  ++C+ C EN+ G   
Sbjct: 732 GFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK--KEAKGLQCDTCRENFYG--L 787

Query: 283 DIPHC----TDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338
           D+ +C     D  G     +CN+   + C C  + +G  C+  +  N  F+ R+  S L 
Sbjct: 788 DVTNCKACDCDTAGSLPGTVCNAKTGQ-CICKPNVEGRQCNKCLEGN--FYLRQNNSFLC 844

Query: 339 LP-RASHKAVVNGNIM 353
           LP        +NG+++
Sbjct: 845 LPCNCDKTGTINGSLL 860



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 62/239 (25%), Positives = 89/239 (37%), Gaps = 53/239 (22%)

Query: 97   EAKECDRP-CVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFV-----TDGP 149
            +A +CD    + G  CN  TGQC+C     G QC  C  G F L  ++ F+      D  
Sbjct: 793  KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852

Query: 150  GNYKYKTKCTWLIEGQPNR--IMRLRFN------HFATECSWDHLYVYDGDS---IYAPL 198
            G       C       P +  +  LR N      +  T  ++ H  + + DS   +   +
Sbjct: 853  GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912

Query: 199  VAAFSG--LIVPERDG---NETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNN 253
                SG  L VP R G   N+  P    + G            N TG          P +
Sbjct: 913  CDPISGQCLCVPNRQGRRCNQCQPGFYISPG------------NATG--------CLPCS 952

Query: 254  CSGRGECKISNSSDTVECECSE-NWKGEACDIPHCTDN-CGF-PHRGICNSSDVRGCSC 309
            C   G      +S T +C C + +  G+ CD   C D+  GF P  G C     + C+C
Sbjct: 953  CHTTGAVNHICNSLTGQCVCQDASIAGQRCD--QCKDHYFGFDPQTGRC-----QPCNC 1004



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 12/31 (38%), Positives = 17/31 (54%)

Query: 111 CNPGTGQCVCPAGWVGEQCQHCGGRFRLTGS 141
           C+  +GQC C A  +G +C HC   F+   S
Sbjct: 708 CHQNSGQCKCKANVIGLRCDHCNFGFKFLRS 738


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 68/253 (26%), Positives = 96/253 (37%), Gaps = 35/253 (13%)

Query: 104 PCVNGGRCNPGTGQCVCPAGWVGEQC-QHCG-GRFRLTGSSGFVTDGPGNYKYKT-KCTW 160
           PC NGG C+  TG+C CP GW G  C Q C  G F    S        G   + T +C  
Sbjct: 233 PCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHC 292

Query: 161 LIEGQPNRIMR-LRFNHFATECSWDHLYVYDGDSIYAPLVAA------FSGLIVPERDGN 213
                 +R      F  F  +CS  H   ++G    +P   A      + G    ER   
Sbjct: 293 TAGYMGDRCQEECPFGSFGFQCS-QHCDCHNGGQC-SPTTGACECEPGYKGPRCQERLCP 350

Query: 214 E-------TVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRG---ECKIS 263
           E       T+P           H  + A     G++  +  + CP    G G    C   
Sbjct: 351 EGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ 410

Query: 264 NSSD----TVECECSENWKGEACDI--------PHCTDNCGFPHRGICNSSDVRGCSCFS 311
           N +D    T  C C+  + GE C +        P+C+  C   + G C+  D   C+C  
Sbjct: 411 NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVD-GSCTCKE 469

Query: 312 DWQGPGCSVPVPA 324
            WQG  C++P P+
Sbjct: 470 GWQGLDCTLPCPS 482



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 71/265 (26%), Positives = 97/265 (36%), Gaps = 56/265 (21%)

Query: 908  TCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQC--VDSNAYV 965
            TC +P++GS C          C  PC   T   +C    +E   C+N   C  +D +   
Sbjct: 457  TC-SPVDGS-CTCKEGWQGLDCTLPCPSGTWGLNC----NESCTCANGAACSPIDGSCSC 510

Query: 966  ASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPV 1025
                 G   E          NCS +C CSH     GC    DP  TG   C+ G + G +
Sbjct: 511  TPGWLGDTCELPCPDGTFGLNCSEHCDCSHA---DGC----DPV-TGHCCCLAG-WTG-I 560

Query: 1026 KMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTT 1085
            +  S  P G + P    N S+               +C C     C  +    +C     
Sbjct: 561  RCDSTCPPGRWGP----NCSV---------------SCSCENGGSCSPEDGSCECAPGFR 601

Query: 1086 GKHCE-TCISGFYGDPTNGGKCQPCKCNGHASL-CNTNTGKCFC------------TTKG 1131
            G  C+  C  GFYG     G  QPC    H+S  C+  +G C C               G
Sbjct: 602  GPLCQRICPPGFYGH----GCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGG 657

Query: 1132 VKGDEC-QLCEVENRYQGNPLRGTC 1155
              G +C QLC   N    +P+ G+C
Sbjct: 658  YFGQDCAQLCSCANNGTCSPIDGSC 682



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 66/261 (25%), Positives = 89/261 (34%), Gaps = 59/261 (22%)

Query: 909  CINPLNGSVCER--PANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDS----- 961
            C     G +C+R  P       C  PC L      C   S  C   S + +C+       
Sbjct: 596  CAPGFRGPLCQRICPPGFYGHGCAQPCPL------CVHSSRPCHHISGICECLPGFSGAL 649

Query: 962  -NAYVASFPFGQ-CMEWYTMS---TCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG-- 1014
             N   A   FGQ C +  + +   TC P    G C C        C     P   G    
Sbjct: 650  CNQVCAGGYFGQDCAQLCSCANNGTCSP--IDGSCQCFPGWIGKDCSQACPPGFWGPACF 707

Query: 1015 ---KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPA--------- 1062
                C  G+          A  G  +  P      C +          CPA         
Sbjct: 708  HACSCHNGA-------SCSAEDGACHCTPGWTGLFCTQ---------RCPAAFFGKDCGR 751

Query: 1063 -CQCNGHSKCINQSICEKCENLTTGKHCE-TCISGFYGDPTNGGKCQPCKCNGHASLCNT 1120
             CQC   + C + S    C    TG+HCE  C  G +G     G  Q C+C  + S C+ 
Sbjct: 752  VCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFG----YGCQQLCECMNN-STCDH 806

Query: 1121 NTGKCFCTT--KGVKGDECQL 1139
             TG C+C+   KG++ D+  L
Sbjct: 807  VTGTCYCSPGFKGIRCDQAAL 827



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 64/243 (26%), Positives = 81/243 (33%), Gaps = 65/243 (26%)

Query: 941  DCTSGSSECMW---CSNMKQCVDSNAYVASFPFGQCM------EWYTMSTCPP----ENC 987
            DC+SG     W   CSN  QC   N  + +   G C+       W     C P    + C
Sbjct: 128  DCSSGCDSDHWGPHCSNRCQC--QNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGC 185

Query: 988  SGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMC 1047
               C C H       G   DP   G+  C  G Y G                 +    +C
Sbjct: 186  QLPCQCRH-------GASCDP-RAGECLCAPG-YTG-----------------VYCEELC 219

Query: 1048 LEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC-ETCISGFYGDPTNGGKC 1106
               S      + CP CQ  G    I       C    TG  C + C  G +G   +    
Sbjct: 220  PPGSHGAHCELRCP-CQNGGTCHHITGECA--CPPGWTGAVCAQPCPPGTFGQNCS---- 272

Query: 1107 QPCKCNGHASLCNTNTGKCFCTTKGVKGDEC--------------QLCEVENRYQGNPLR 1152
            Q C C+ H   C+  TG+C CT  G  GD C              Q C+  N  Q +P  
Sbjct: 273  QDCPCH-HGGQCDHVTGQCHCTA-GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTT 330

Query: 1153 GTC 1155
            G C
Sbjct: 331  GAC 333



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 11/81 (13%)

Query: 253 NCSGRGECKISNSSDTVE--CECSENWKGEACDIP--------HCTDNCGFPHRGICNSS 302
           NCS    C    +   V+  C C E W+G  C +P        +C ++C   +   C+  
Sbjct: 445 NCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPI 504

Query: 303 DVRGCSCFSDWQGPGCSVPVP 323
           D   CSC   W G  C +P P
Sbjct: 505 D-GSCSCTPGWLGDTCELPCP 524



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 54/229 (23%), Positives = 75/229 (32%), Gaps = 47/229 (20%)

Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEG 164
           C NG  CNP TG CVC AG+ G +C+         G+ G     P   ++   C      
Sbjct: 148 CQNGALCNPITGACVCAAGFRGWRCE----ELCAPGTHGKGCQLPCQCRHGASC------ 197

Query: 165 QPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSG 224
                     +  A EC     Y      +Y         L  P   G          +G
Sbjct: 198 ----------DPRAGECLCAPGYT----GVYC------EELCPPGSHGAHCELRCPCQNG 237

Query: 225 YALLHFFSDAAYNLTGFNITYSFDMCP-----NNCSGRGECKISNSSD--TVECECSENW 277
               H   + A    G+        CP      NCS    C      D  T +C C+  +
Sbjct: 238 GTCHHITGECACP-PGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGY 296

Query: 278 KGEAC--DIP------HCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGC 318
            G+ C  + P       C+ +C   + G C S     C C   ++GP C
Sbjct: 297 MGDRCQEECPFGSFGFQCSQHCDCHNGGQC-SPTTGACECEPGYKGPRC 344



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 55/247 (22%), Positives = 75/247 (30%), Gaps = 56/247 (22%)

Query: 99  KECDRPCV--NGGRCNPGTGQCVCPAGWVGEQCQ----------HCGGRFRLTGSSGFVT 146
           K C  PC   +G  C+P  G+C+C  G+ G  C+          HC  R     + G   
Sbjct: 183 KGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQ-NGGTCH 241

Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206
              G        T  +  QP          F   CS D    + G               
Sbjct: 242 HITGECACPPGWTGAVCAQP-----CPPGTFGQNCSQDCPCHHGGQC------------- 283

Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSS 266
                 +    +   T+GY       +  +   GF  +   D     C   G+C    S 
Sbjct: 284 ------DHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD-----CHNGGQC----SP 328

Query: 267 DTVECECSENWKGEACDI---------PHCTDNCGFPHRGICNSSDVRG-CSCFSDWQGP 316
            T  CEC   +KG  C           P CT  C        +   V G C+C   W G 
Sbjct: 329 TTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGH 388

Query: 317 GCSVPVP 323
            C+   P
Sbjct: 389 HCNESCP 395



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)

Query: 98  AKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQ 130
           ++ CD  C NGG+C+P TG C C  G+ G +CQ
Sbjct: 315 SQHCD--CHNGGQCSPTTGACECEPGYKGPRCQ 345



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 18/90 (20%)

Query: 250 CPN-----NCSGRGECKISNSSDTVE--CECSENWKGEACDIP--------HCTDNCGFP 294
           CP+     NC+    C    +   ++  C C+  W G+ C++P        +C+++C   
Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS 539

Query: 295 HRGICNSSDVRG-CSCFSDWQGPGCSVPVP 323
           H   C+   V G C C + W G  C    P
Sbjct: 540 HADGCD--PVTGHCCCLAGWTGIRCDSTCP 567



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 19/53 (35%), Positives = 21/53 (39%), Gaps = 2/53 (3%)

Query: 79  CEAEAAAAAAAVSGSAAAEAKECDR--PCVNGGRCNPGTGQCVCPAGWVGEQC 129
           C         AVS +A      C     C NGG C+P  G C C  GW G  C
Sbjct: 424 CAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC 476



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 12/26 (46%), Positives = 16/26 (61%)

Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQ 130
           C NG  C+P  G C C  GW+G+ C+
Sbjct: 495 CANGAACSPIDGSCSCTPGWLGDTCE 520



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 12/25 (48%), Positives = 15/25 (60%)

Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQC 129
           C N G C+P  G C C  GW+G+ C
Sbjct: 669 CANNGTCSPIDGSCQCFPGWIGKDC 693



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 19/70 (27%)

Query: 79  CEAEAAAAAAAVSGSAAAE----AKECDRPCVNG---------------GRCNPGTGQCV 119
           C     AA + + GS +         C+ PC +G                 C+P TG C 
Sbjct: 493 CTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC 552

Query: 120 CPAGWVGEQC 129
           C AGW G +C
Sbjct: 553 CLAGWTGIRC 562



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 20/67 (29%), Positives = 24/67 (35%), Gaps = 11/67 (16%)

Query: 271 CECSENWKGEACDI--------PHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPV 322
           CEC   + G  C+           C   C   + G C+  D   C CF  W G  CS   
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPID-GSCQCFPGWIGKDCSQAC 697

Query: 323 PANQSFW 329
           P    FW
Sbjct: 698 P--PGFW 702



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 13/80 (16%)

Query: 253 NCSGRGECKISNSSDTVECECSENWKGEACDI--------PHCTDNCGFPHRGICNSSDV 304
           +C+  G C   + S    C+C   W G+ C          P C   C   H G   S++ 
Sbjct: 668 SCANNGTCSPIDGS----CQCFPGWIGKDCSQACPPGFWGPACFHACSC-HNGASCSAED 722

Query: 305 RGCSCFSDWQGPGCSVPVPA 324
             C C   W G  C+   PA
Sbjct: 723 GACHCTPGWTGLFCTQRCPA 742



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 94  AAAEAKECDR--PCVNGGRCNPGTGQCVCPAGWVGEQCQ 130
           AA   K+C R   C NG  C+  +G+C C  G+ G+ C+
Sbjct: 742 AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE 780



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 19/81 (23%)

Query: 68  LSPPLLLLLLPCEAEAAAAAAAVSGSAAAE-----------------AKECDRPCV--NG 108
           L  P   L  PC+A+   +   V+G+   +                    C  PC   NG
Sbjct: 353 LHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNG 412

Query: 109 GRCNPGTGQCVCPAGWVGEQC 129
             C+  TG C C  G++GE C
Sbjct: 413 ADCHSITGGCTCAPGFMGEVC 433



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 13/26 (50%), Positives = 15/26 (57%)

Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQ 130
           C NGG C+P  G C C  G+ G  CQ
Sbjct: 581 CENGGSCSPEDGSCECAPGFRGPLCQ 606



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 15/82 (18%)

Query: 245 YSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDI--------PHCTDNCGFPHR 296
           +   +C   C   G C    S DT  C C   W G  C          PHC++ C   + 
Sbjct: 98  FCIPLCTEECV-HGRCV---SPDT--CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNG 151

Query: 297 GICNSSDVRGCSCFSDWQGPGC 318
            +CN      C C + ++G  C
Sbjct: 152 ALCNPI-TGACVCAAGFRGWRC 172



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 14/33 (42%), Positives = 15/33 (45%), Gaps = 1/33 (3%)

Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQC-QHCGGRF 136
           C NG  C+   G C C  GW G  C Q C   F
Sbjct: 712 CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAF 744



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 6/41 (14%)

Query: 279 GEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCS 319
           G+ C IP CT+ C     G C S D   C C   W GP CS
Sbjct: 96  GDFC-IPLCTEECV---HGRCVSPDT--CHCEPGWGGPDCS 130


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
           sapiens]
          Length = 3667

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 8/114 (7%)

Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
           CGG F            PG YK    C W+IE +P   +++ F  F TE ++D L V+DG
Sbjct: 855 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 914

Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            ++ +PL+ +++G  VP+         + ++S +  L F +D + +  GF I Y
Sbjct: 915 PNLLSPLLGSYNGTQVPQ--------FLFSSSNFIYLLFTTDNSRSNNGFKIHY 960



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 12/116 (10%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG   LTGSSGF+     P  Y +   C W I    + ++ L F  F+ E ++D LY+Y
Sbjct: 1548 CGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DG    +PL+ +F    +PER        + ++S    L F SD + + TGF++ Y
Sbjct: 1606 DGPDSNSPLIGSFQDSKLPER--------IESSSNTMHLAFRSDGSVSYTGFHLEY 1653



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 17/158 (10%)

Query: 132  CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190
            CGGRF+   S   ++ G P  Y    +C W+IE  P  I+ L+F  F TE S D L V+D
Sbjct: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1433

Query: 191  GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250
            G      L+   SG ++PE         + +T     + F +D   + +GF I +S  + 
Sbjct: 1434 GPPENDMLLKEISGSLIPE--------GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485

Query: 251  --------PNNCSGRGECKISNSSDTVECECSENWKGE 280
                    P N +  G+ +    +   +C+     +GE
Sbjct: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1523



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 15/114 (13%)

Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206
           D P  Y     C W I   P   + L FN F  E  +D L V DGDS  +P++  F+G  
Sbjct: 696 DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAE 755

Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGEC 260
           VP          + + S    L F +D + +  GFNITY       N  G  EC
Sbjct: 756 VPS--------HLTSNSHILRLEFQADHSMSGRGFNITY-------NTFGHNEC 794



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 16/139 (11%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
           CGG  R  GSSG ++    P  Y     CTW I  +P   + L F  F  E  +D+L + 
Sbjct: 201 CGGTMR--GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258

Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDM 249
             +    P     SG+ +P        P +++   +  LHF +D+ +   GF+  Y    
Sbjct: 259 GSE----PPTIWLSGMNIP--------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSS 306

Query: 250 CPNNCSGRGECKISNSSDT 268
              + +  GE +  N + T
Sbjct: 307 TLTHTTSTGELEEHNRTTT 325



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 14/152 (9%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       +      P  Y     C W I       ++++   FATE +WD L  YDG
Sbjct: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1958

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS---FD 248
                AP + ++SG  +P          + +TS    L+F SD + +  GF++ Y+    D
Sbjct: 1959 GDNNAPRLGSYSGTTIPHL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010

Query: 249  MCPNNCSGRGECKISNS---SDTVECECSENW 277
             CP   +     KI +     D V  +C + +
Sbjct: 2011 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGY 2042



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 51/187 (27%), Positives = 72/187 (38%), Gaps = 39/187 (20%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG   ++  SG +     PGNY     CTW I       + L+F +F+TE   D+L V 
Sbjct: 2071 CGGA--MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2128

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI---TYS 246
             G S  + ++   SG  +P          + +T+    L+F SD + N  GF+I    Y 
Sbjct: 2129 SGSSETSTVIGRLSGPQIPS--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2180

Query: 247  FDMCPNNCSGRGECKISNS---SDTVECEC------------------SENWKGEACDIP 285
               CP+    R    I N      T+  EC                  S NW      +P
Sbjct: 2181 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNH---PLP 2237

Query: 286  HCTDNCG 292
             C   CG
Sbjct: 2238 RCEALCG 2244



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188
           CGG   L G +G + + PG    Y     CTW+I  +    +++ F  FA E  +D+L +
Sbjct: 25  CGGT--LKGLNGTI-ESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81

Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFD 248
           YDG           +G  +P        P V +T     L   SD A +  GF + Y  +
Sbjct: 82  YDGHPHPTNFRTRLTGFHLP--------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-E 132

Query: 249 MCPNNCSGRG 258
           +  ++C   G
Sbjct: 133 LQSSSCGNPG 142



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 10/110 (9%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       + +    P  Y     C WL+   P   + + F    TE  +D + V+DG
Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2302

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241
                +P +  FS        GN  +  V +TS   L+ F SD  +  +GF
Sbjct: 2303 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGF 2342



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYV 188
           CG    L G SG  T    P  Y    +C W+I     N+++++ F  F  E  +D L +
Sbjct: 508 CGSN--LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 565

Query: 189 YDGDSIYAP--LVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DG  +  P  ++   +G  VP+         +V+ S    LH  +D +    GF + Y
Sbjct: 566 GDGGEVGDPRTVLQVLTGSFVPDL--------IVSMSSQMWLHLQTDESVGSVGFKVNY 616



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 31/184 (16%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG  R  G SG +     P  Y     CTW ++    + ++  F+ F  E   D+L + 
Sbjct: 1027 CGGDVR--GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1084

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT---YS 246
            +  S   PL A  +G  +P      T+   +  +  A L F SD + +  GFNIT   Y+
Sbjct: 1085 ENGSFTQPL-ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138

Query: 247  FDMCPNNCSGRGECKIS---NSSDTVECECSENWKGE---------------ACDIPHCT 288
             + C +    +   +I       DT+   CS  ++ E               +  +P C 
Sbjct: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198

Query: 289  DNCG 292
              CG
Sbjct: 1199 AECG 1202



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 19/139 (13%)

Query: 113  PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMR 171
            P   Q +CPA              RL  +   ++ G P +Y     C W I  +    + 
Sbjct: 2409 PPVCQVLCPAN-----------ELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNIT 2457

Query: 172  LRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFF 231
            +    F TE  +D L VYDG +I +P++ + SG          +   + +      L + 
Sbjct: 2458 MFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSG-------DYSSAFNITSNGHEVFLQWS 2510

Query: 232  SDAAYNLTGFNITYSFDMC 250
            +D   N  GF I Y    C
Sbjct: 2511 ADHGNNKKGFRIRYIAFYC 2529



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)

Query: 105  CVNGGRCNPGTGQCVCPAG----WVGE--QC-QHCGGRFRLTGSSGFVTDG--PGNYKYK 155
            C +G R   GT + +C  G    W     +C   CG     T + G +     P NY+  
Sbjct: 1168 CSSGYRLE-GTSEIICLGGGRRVWSAPLPRCVAECGAS--ATNNEGILLSPNYPLNYENN 1224

Query: 156  TKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNET 215
             +C + I+ Q  + + +    F      D L +YDG      L+ AF+G        +  
Sbjct: 1225 HECIYSIQVQAGKGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTG-------ASMR 1276

Query: 216  VPEVVATSGYALLHFFSDAAYNLTGFNITY-SFDMCPNNCSGRG 258
               + +TS    L F SD      GF + Y SF++  ++C   G
Sbjct: 1277 GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL--SHCEDPG 1318


>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
           sapiens]
          Length = 3538

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 8/114 (7%)

Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
           CGG F            PG YK    C W+IE +P   +++ F  F TE ++D L V+DG
Sbjct: 791 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 850

Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            ++ +PL+ +++G  VP+         + ++S +  L F +D + +  GF I Y
Sbjct: 851 PNLLSPLLGSYNGTQVPQ--------FLFSSSNFIYLLFTTDNSRSNNGFKIHY 896



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 12/116 (10%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG   LTGSSGF+     P  Y +   C W I    + ++ L F  F+ E ++D LY+Y
Sbjct: 1484 CGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DG    +PL+ +F    +PER        + ++S    L F SD + + TGF++ Y
Sbjct: 1542 DGPDSNSPLIGSFQDSKLPER--------IESSSNTMHLAFRSDGSVSYTGFHLEY 1589



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 17/158 (10%)

Query: 132  CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190
            CGGRF+   S   ++ G P  Y    +C W+IE  P  I+ L+F  F TE S D L V+D
Sbjct: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1369

Query: 191  GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250
            G      L+   SG ++PE         + +T     + F +D   + +GF I +S  + 
Sbjct: 1370 GPPENDMLLKEISGSLIPE--------GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1421

Query: 251  --------PNNCSGRGECKISNSSDTVECECSENWKGE 280
                    P N +  G+ +    +   +C+     +GE
Sbjct: 1422 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1459



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 15/114 (13%)

Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206
           D P  Y     C W I   P   + L FN F  E  +D L V DGDS  +P++  F+G  
Sbjct: 632 DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAE 691

Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGEC 260
           VP          + + S    L F +D + +  GFNITY       N  G  EC
Sbjct: 692 VPS--------HLTSNSHILRLEFQADHSMSGRGFNITY-------NTFGHNEC 730



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 14/152 (9%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       +      P  Y     C W I       ++++   FATE +WD L  YDG
Sbjct: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1894

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS---FD 248
                AP + ++SG  +P          + +TS    L+F SD + +  GF++ Y+    D
Sbjct: 1895 GDNNAPRLGSYSGTTIPHL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946

Query: 249  MCPNNCSGRGECKISNS---SDTVECECSENW 277
             CP   +     KI +     D V  +C + +
Sbjct: 1947 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGY 1978



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 51/187 (27%), Positives = 72/187 (38%), Gaps = 39/187 (20%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG   ++  SG +     PGNY     CTW I       + L+F +F+TE   D+L V 
Sbjct: 2007 CGGA--MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2064

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI---TYS 246
             G S  + ++   SG  +P          + +T+    L+F SD + N  GF+I    Y 
Sbjct: 2065 SGSSETSTVIGRLSGPQIPS--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2116

Query: 247  FDMCPNNCSGRGECKISNS---SDTVECEC------------------SENWKGEACDIP 285
               CP+    R    I N      T+  EC                  S NW      +P
Sbjct: 2117 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNH---PLP 2173

Query: 286  HCTDNCG 292
             C   CG
Sbjct: 2174 RCEALCG 2180



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 16/116 (13%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
           CGG  R  GSSG ++    P  Y     CTW I  +P   + L F  F  E  +D+L + 
Sbjct: 241 CGGTMR--GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298

Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
             +    P     SG+ +P        P +++   +  LHF +D+ +   GF+  Y
Sbjct: 299 GSE----PPTIWLSGMNIP--------PPIISNKNWLRLHFVTDSNHRYRGFSAPY 342



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188
           CGG   L G +G + + PG    Y     CTW+I  +    +++ F  FA E  +D+L +
Sbjct: 65  CGGT--LKGLNGTI-ESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121

Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFD 248
           YDG           +G  +P        P V +T     L   SD A +  GF + Y  +
Sbjct: 122 YDGHPHPTNFRTRLTGFHLP--------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-E 172

Query: 249 MCPNNCSGRG 258
           +  ++C   G
Sbjct: 173 LQSSSCGNPG 182



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 10/110 (9%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       + +    P  Y     C WL+   P   + + F    TE  +D + V+DG
Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241
                +P +  FS        GN  +  V +TS   L+ F SD  +  +GF
Sbjct: 2239 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGF 2278



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYV 188
           CG    L G SG  T    P  Y    +C W+I     N+++++ F  F  E  +D L +
Sbjct: 444 CGSN--LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 501

Query: 189 YDGDSIYAP--LVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DG  +  P  ++   +G  VP+         +V+ S    LH  +D +    GF + Y
Sbjct: 502 GDGGEVGDPRTVLQVLTGSFVPDL--------IVSMSSQMWLHLQTDESVGSVGFKVNY 552



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 31/184 (16%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG  R  G SG +     P  Y     CTW ++    + ++  F+ F  E   D+L + 
Sbjct: 963  CGGDVR--GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1020

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT---YS 246
            +  S   PL A  +G  +P      T+   +  +  A L F SD + +  GFNIT   Y+
Sbjct: 1021 ENGSFTQPL-ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074

Query: 247  FDMCPNNCSGRGECKIS---NSSDTVECECSENWKGE---------------ACDIPHCT 288
             + C +    +   +I       DT+   CS  ++ E               +  +P C 
Sbjct: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134

Query: 289  DNCG 292
              CG
Sbjct: 1135 AECG 1138



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 19/139 (13%)

Query: 113  PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMR 171
            P   Q +CPA              RL  +   ++ G P +Y     C W I  +    + 
Sbjct: 2345 PPVCQVLCPAN-----------ELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNIT 2393

Query: 172  LRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFF 231
            +    F TE  +D L VYDG +I +P++ + SG          +   + +      L + 
Sbjct: 2394 MFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSG-------DYSSAFNITSNGHEVFLQWS 2446

Query: 232  SDAAYNLTGFNITYSFDMC 250
            +D   N  GF I Y    C
Sbjct: 2447 ADHGNNKKGFRIRYIAFYC 2465



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)

Query: 105  CVNGGRCNPGTGQCVCPAG----WVGE--QC-QHCGGRFRLTGSSGFVTDG--PGNYKYK 155
            C +G R   GT + +C  G    W     +C   CG     T + G +     P NY+  
Sbjct: 1104 CSSGYRLE-GTSEIICLGGGRRVWSAPLPRCVAECGAS--ATNNEGILLSPNYPLNYENN 1160

Query: 156  TKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNET 215
             +C + I+ Q  + + +    F      D L +YDG      L+ AF+G        +  
Sbjct: 1161 HECIYSIQVQAGKGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTG-------ASMR 1212

Query: 216  VPEVVATSGYALLHFFSDAAYNLTGFNITY-SFDMCPNNCSGRG 258
               + +TS    L F SD      GF + Y SF++  ++C   G
Sbjct: 1213 GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL--SHCEDPG 1254


>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
          Length = 3707

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 8/114 (7%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG F            PG YK    C W+IE +P   +++ F  F TE ++D L V+DG
Sbjct: 895  CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 954

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
             ++ +PL+ +++G  VP+         + ++S +  L F +D + +  GF I Y
Sbjct: 955  PNLLSPLLGSYNGTQVPQ--------FLFSSSNFIYLLFTTDNSRSNNGFKIHY 1000



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 12/116 (10%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG   LTGSSGF+     P  Y +   C W I    + ++ L F  F+ E ++D LY+Y
Sbjct: 1588 CGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1645

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DG    +PL+ +F    +PER        + ++S    L F SD + + TGF++ Y
Sbjct: 1646 DGPDSNSPLIGSFQDSKLPER--------IESSSNTMHLAFRSDGSVSYTGFHLEY 1693



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 17/158 (10%)

Query: 132  CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190
            CGGRF+   S   ++ G P  Y    +C W+IE  P  I+ L+F  F TE S D L V+D
Sbjct: 1414 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1473

Query: 191  GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250
            G      L+   SG ++PE         + +T     + F +D   + +GF I +S  + 
Sbjct: 1474 GPPENDMLLKEISGSLIPE--------GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1525

Query: 251  --------PNNCSGRGECKISNSSDTVECECSENWKGE 280
                    P N +  G+ +    +   +C+     +GE
Sbjct: 1526 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1563



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 15/114 (13%)

Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206
           D P  Y     C W I   P   + L FN F  E  +D L V DGDS  +P++  F+G  
Sbjct: 736 DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAE 795

Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGEC 260
           VP          + + S    L F +D + +  GFNITY       N  G  EC
Sbjct: 796 VPS--------HLTSNSHILRLEFQADHSMSGRGFNITY-------NTFGHNEC 834



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 16/139 (11%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
           CGG  R  GSSG ++    P  Y     CTW I  +P   + L F  F  E  +D+L + 
Sbjct: 241 CGGTMR--GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298

Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDM 249
             +    P     SG+ +P        P +++   +  LHF +D+ +   GF+  Y    
Sbjct: 299 GSE----PPTIWLSGMNIP--------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSS 346

Query: 250 CPNNCSGRGECKISNSSDT 268
              + +  GE +  N + T
Sbjct: 347 TLTHTTSTGELEEHNRTTT 365



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 14/152 (9%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       +      P  Y     C W I       ++++   FATE +WD L  YDG
Sbjct: 1939 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1998

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS---FD 248
                AP + ++SG  +P          + +TS    L+F SD + +  GF++ Y+    D
Sbjct: 1999 GDNNAPRLGSYSGTTIPHL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2050

Query: 249  MCPNNCSGRGECKISNS---SDTVECECSENW 277
             CP   +     KI +     D V  +C + +
Sbjct: 2051 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGY 2082



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 51/187 (27%), Positives = 72/187 (38%), Gaps = 39/187 (20%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG   ++  SG +     PGNY     CTW I       + L+F +F+TE   D+L V 
Sbjct: 2111 CGGA--MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2168

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI---TYS 246
             G S  + ++   SG  +P          + +T+    L+F SD + N  GF+I    Y 
Sbjct: 2169 SGSSETSTVIGRLSGPQIPS--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2220

Query: 247  FDMCPNNCSGRGECKISNS---SDTVECEC------------------SENWKGEACDIP 285
               CP+    R    I N      T+  EC                  S NW      +P
Sbjct: 2221 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNH---PLP 2277

Query: 286  HCTDNCG 292
             C   CG
Sbjct: 2278 RCEALCG 2284



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188
           CGG   L G +G + + PG    Y     CTW+I  +    +++ F  FA E  +D+L +
Sbjct: 65  CGGT--LKGLNGTI-ESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121

Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFD 248
           YDG           +G  +P        P V +T     L   SD A +  GF + Y  +
Sbjct: 122 YDGHPHPTNFRTRLTGFHLP--------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-E 172

Query: 249 MCPNNCSGRG 258
           +  ++C   G
Sbjct: 173 LQSSSCGNPG 182



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 10/110 (9%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG       + +    P  Y     C WL+   P   + + F    TE  +D + V+DG
Sbjct: 2283 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2342

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241
                +P +  FS        GN  +  V +TS   L+ F SD  +  +GF
Sbjct: 2343 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGF 2382



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%)

Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYV 188
           CG    L G SG  T    P  Y    +C W+I     N+++++ F  F  E  +D L +
Sbjct: 548 CGSN--LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 605

Query: 189 YDGDSIYAP--LVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DG  +  P  ++   +G  VP+         +V+ S    LH  +D +    GF + Y
Sbjct: 606 GDGGEVGDPRTVLQVLTGSFVPDL--------IVSMSSQMWLHLQTDESVGSVGFKVNY 656



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 31/184 (16%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189
            CGG  R  G SG +     P  Y     CTW ++    + ++  F+ F  E   D+L + 
Sbjct: 1067 CGGDVR--GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1124

Query: 190  DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT---YS 246
            +  S   PL A  +G  +P      T+   +  +  A L F SD + +  GFNIT   Y+
Sbjct: 1125 ENGSFTQPL-ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1178

Query: 247  FDMCPNNCSGRGECKIS---NSSDTVECECSENWKGE---------------ACDIPHCT 288
             + C +    +   +I       DT+   CS  ++ E               +  +P C 
Sbjct: 1179 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1238

Query: 289  DNCG 292
              CG
Sbjct: 1239 AECG 1242



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 19/139 (13%)

Query: 113  PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMR 171
            P   Q +CPA              RL  +   ++ G P +Y     C W I  +    + 
Sbjct: 2449 PPVCQVLCPAN-----------ELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNIT 2497

Query: 172  LRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFF 231
            +    F TE  +D L VYDG +I +P++ + SG          +   + +      L + 
Sbjct: 2498 MFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSG-------DYSSAFNITSNGHEVFLQWS 2550

Query: 232  SDAAYNLTGFNITYSFDMC 250
            +D   N  GF I Y    C
Sbjct: 2551 ADHGNNKKGFRIRYIAFYC 2569



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)

Query: 105  CVNGGRCNPGTGQCVCPAG----WVGE--QC-QHCGGRFRLTGSSGFVTDG--PGNYKYK 155
            C +G R   GT + +C  G    W     +C   CG     T + G +     P NY+  
Sbjct: 1208 CSSGYRLE-GTSEIICLGGGRRVWSAPLPRCVAECGAS--ATNNEGILLSPNYPLNYENN 1264

Query: 156  TKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNET 215
             +C + I+ Q  + + +    F      D L +YDG      L+ AF+G        +  
Sbjct: 1265 HECIYSIQVQAGKGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTG-------ASMR 1316

Query: 216  VPEVVATSGYALLHFFSDAAYNLTGFNITY-SFDMCPNNCSGRG 258
               + +TS    L F SD      GF + Y SF++  ++C   G
Sbjct: 1317 GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL--SHCEDPG 1358


>gi|16945972 kelch domain containing 3 [Homo sapiens]
          Length = 382

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 58/262 (22%), Positives = 108/262 (41%), Gaps = 22/262 (8%)

Query: 384 RSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYA 443
           R VN+  V  GH       ++Y +GG        T      HI N   +  T     + A
Sbjct: 13  RRVNHAAVAVGH-------RVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSA 65

Query: 444 VVGHSAHIVTLKNGRVVMLVIF------GHCPLYGYISNVQEYDLDKNTWSILHTQGALV 497
           + G +  +  ++ G   +L+        G     G  + +  +D++ + W      G + 
Sbjct: 66  IRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVP 125

Query: 498 QGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTIL---KDSRFFR 554
               GHS+      + +Y+ GGY+   A+ +  ++D+++ D  T  WT++        +R
Sbjct: 126 GARDGHSACV--LGKIMYIFGGYEQ-QADCF--SNDIHKLDTSTMTWTLICTKGSPARWR 180

Query: 555 YLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNR 614
             H+A ++   M VFGG            + + +    +D   + W   P   +  +  R
Sbjct: 181 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRR 240

Query: 615 FGHSAVLHNSTMYVFGGFNSLL 636
             HSA  +N  +Y+FGG+N+ L
Sbjct: 241 -SHSAFGYNGELYIFGGYNARL 261



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 61/253 (24%), Positives = 108/253 (42%), Gaps = 32/253 (12%)

Query: 341 RASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDL-----ASREWL---PLNRSVNNVV-- 390
           R +H AV  G+ ++  GGY  +  DY  +   D+      S  W    P+  ++      
Sbjct: 14  RVNHAAVAVGHRVYSFGGYC-SGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAPV 72

Query: 391 ---VRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGH 447
              +RYGHS  L  D + ++GG+ D+ G   N L  F ++   W           A  GH
Sbjct: 73  VPYMRYGHSTVLIDDTVLLWGGRNDTEG-ACNVLYAFDVNTHKWFTPRVSGTVPGARDGH 131

Query: 448 SAHIVTLKNGRVVMLVIFGHCPLYG--YISNVQEYDLDKNTWSILHTQGALVQGGYGHSS 505
           SA ++    G++  + IFG        + +++ + D    TW+++ T+G+  +    HS+
Sbjct: 132 SACVL----GKI--MYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSA 185

Query: 506 VYDHRTRALYVHGG----YKAFSANKYRLADDLYRYDVDTQMWTILKDSRFF---RYLHT 558
                   +YV GG    +  F +N     + +  +D  T+ W     +      R  H+
Sbjct: 186 TM--LGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHS 243

Query: 559 AVIVSGTMLVFGG 571
           A   +G + +FGG
Sbjct: 244 AFGYNGELYIFGG 256



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 21/244 (8%)

Query: 341 RASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALY 400
           R  H  V+  + + + GG        N++ A+D+ + +W     S      R GHS  + 
Sbjct: 77  RYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVL 136

Query: 401 KDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVV 460
              +Y++GG        +N++        +W L+  K         HSA ++        
Sbjct: 137 GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSH----- 191

Query: 461 MLVIFGHCPLYG--------YISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTR 512
           M V  G    +G        Y + ++ +D     W        L +G   HS+       
Sbjct: 192 MYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAF--GYNG 249

Query: 513 ALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILK---DSRFFRYLHTAVIVSGTMLVF 569
            LY+ GGY   +A   R   DL++++  +  W  ++        R      IV   +++F
Sbjct: 250 ELYIFGGY---NARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLF 306

Query: 570 GGNT 573
           GG +
Sbjct: 307 GGTS 310


>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
          Length = 539

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 53/201 (26%), Positives = 79/201 (39%), Gaps = 34/201 (16%)

Query: 971  GQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQ 1030
            G+C      + C  +N    C C H    P CG C            + +Y+G    P  
Sbjct: 295  GRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKC------------KKNYQGRPWSP-- 340

Query: 1031 APTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KC-----INQSICEKCENLT 1084
               G++ P P   ++ C+       S      C+C GHS +C     +N  IC  C++ T
Sbjct: 341  ---GSYLPIPKGTANTCIP------SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNT 391

Query: 1085 TGKHCETCISGFYGDPT----NGGKCQPCKCNGHASLCNTNTGKCFCTTK-GVKGDECQL 1139
             G+HCE C  G++ + +    +   C  C CN   S+ +   G  FC  K G  G +C  
Sbjct: 392  RGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDE 451

Query: 1140 CEVENRYQGNPLRGTCYYTLL 1160
            C   N +        C   LL
Sbjct: 452  CLPGNSWHYGCQPNVCDNELL 472


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 58/205 (28%), Positives = 74/205 (36%), Gaps = 62/205 (30%)

Query: 981  TCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQP 1040
            TC P   +G C CSH  E P C            +C+ G Y  P     QA      P P
Sbjct: 714  TCDPN--TGICVCSHHTEGPSCE-----------RCLPGFYGNP--FAGQADDCQPCPCP 758

Query: 1041 LLNSSMCLEDSRYNWSFIHCPA------------------------------CQCNGH-- 1068
              ++   + +SR      HCP                               CQC+G+  
Sbjct: 759  GQSACTTIPESR-EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVD 817

Query: 1069 ----SKCINQS-ICEKCENLTTGKHCETCISGFYGD---PTNGGKCQPCKCNGHASL--- 1117
                  C   S  C +C + TTG HCE C  GFYG    P    KC PC C+   S+   
Sbjct: 818  PNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQ 877

Query: 1118 --CNTNTGKCFCTTKGVKGDECQLC 1140
              C+  TG+C C    V   +C  C
Sbjct: 878  MPCDPVTGQCSCLPH-VTARDCSRC 901



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 39/102 (38%), Positives = 52/102 (50%), Gaps = 11/102 (10%)

Query: 1057 FIHCPACQCNGHSKCI-NQSICEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNG 1113
            +  C  C CN H  C  N  IC  C + T G  CE C+ GFYG+P  G    CQPC C G
Sbjct: 701  YASCVPCTCNQHGTCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759

Query: 1114 HASLCNT--NTGKCFCT--TKGVKGDECQLCEVENRYQGNPL 1151
              S C T   + +  CT    G +G  C++C  ++ + G+PL
Sbjct: 760  Q-SACTTIPESREVVCTHCPPGQRGRRCEVC--DDGFFGDPL 798



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 11/99 (11%)

Query: 1049 EDSRYNWS-FIHCPACQCNG----HSKCINQSICEKCENLTTGKHCETCISGFYGDPTNG 1103
            +++ Y+W   + C  C C      H +C +   C  C+   TG  C+ C+ GF+    + 
Sbjct: 368  QENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCA-CKPTVTGWKCDRCLPGFHS--LSE 424

Query: 1104 GKCQPCKCNGHASL--CNTNTGKCFCTTKGVKGDECQLC 1140
            G C+PC CN   SL  C+  +G+C C  + V+G+ C  C
Sbjct: 425  GGCRPCTCNPAGSLDTCDPRSGRCPC-KENVEGNLCDRC 462



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 22/108 (20%)

Query: 1063 CQCNGH-SKC----INQSICEKCENLTTGKHCETCISGFYGDPTNGG------KCQPCKC 1111
            C+CNGH S+C      Q  C +C++ TTG  CE C+  F   P   G      +C PC C
Sbjct: 271  CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329

Query: 1112 NGHASLCNTNT---------GKCFCTTKGVKGDECQLCEVENRYQGNP 1150
            +G +  C  +          G+C        G  C+ C+ EN Y  +P
Sbjct: 330  SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQ-ENFYHWDP 376



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 35/95 (36%), Positives = 41/95 (43%), Gaps = 20/95 (21%)

Query: 1060 CPACQCNGHSK-CI----------NQSICEKCENLTTGKHCETCISGFY-GDPTNGGKCQ 1107
            C  C C+G S+ C           +   C  C + T G HCE C   FY  DP     CQ
Sbjct: 324  CLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM--PCQ 381

Query: 1108 PCKCNGHASL---CNTNTGKCFC--TTKGVKGDEC 1137
            PC C    SL   C+ +TG C C  T  G K D C
Sbjct: 382  PCDCQSAGSLHLQCD-DTGTCACKPTVTGWKCDRC 415



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 51/189 (26%), Positives = 74/189 (39%), Gaps = 39/189 (20%)

Query: 979  MSTCPPENCSGYCT----------CSHCLEQ-PGCGWCTDPSNTGKGKCIEGSY--KGPV 1025
            +  C P   SG+C           C HC E   G      P++    KC+  S   +G V
Sbjct: 821  VGNCDP--LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPAD----KCMPCSCHPQGSV 874

Query: 1026 --KMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIH------CPACQCNG----HSKCIN 1073
              +MP    TG     P + +  C   SR    F        C +C+C+       +C  
Sbjct: 875  SEQMPCDPVTGQCSCLPHVTARDC---SRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHP 931

Query: 1074 QSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCN--GHASLCNTNTGKCFCTTKG 1131
            ++    C    TG+ C+ C  GF+G    G  C+ C+C+  G AS      G C C   G
Sbjct: 932  KTGQCTCRPGVTGQACDRCQLGFFGFSIKG--CRACRCSPLGAASAQCHENGTCVC-RPG 988

Query: 1132 VKGDECQLC 1140
             +G +C  C
Sbjct: 989  FEGYKCDRC 997



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 52/222 (23%), Positives = 69/222 (31%), Gaps = 54/222 (24%)

Query: 939  CGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMST-----CPPENCSGY--- 990
            CG   +G   C  C +     D    +   PF Q   W   +      C P NCSG    
Sbjct: 280  CGPDVAGQLACR-CQHNTTGTDCERCL---PFFQDRPWARGTAEAAHECLPCNCSGRSEE 335

Query: 991  CT--------------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQA----- 1031
            CT              C HC +      C         +C E  Y    +MP Q      
Sbjct: 336  CTFDRELFRSTGHGGRCHHCRDHTAGPHCE--------RCQENFYHWDPRMPCQPCDCQS 387

Query: 1032 ---------PTGNFYPQPLLNSSMCLE--DSRYNWSFIHCPACQCNGHSK---CINQSIC 1077
                      TG    +P +    C       ++ S   C  C CN       C  +S  
Sbjct: 388  AGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR 447

Query: 1078 EKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASLC 1118
              C+    G  C+ C  G +   P N   C  C C GH+ +C
Sbjct: 448  CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVC 489



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 31/112 (27%), Positives = 40/112 (35%), Gaps = 16/112 (14%)

Query: 637 LSDILVFTSEQCDAHRSEAACLAAGP-GIRCVWNTGSSQCIS---------WALATDEQ- 685
           +SD  V    +C+ H SE     AG    RC  NT  + C           WA  T E  
Sbjct: 262 VSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAA 321

Query: 686 EEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCV-PRNHSCSE 736
            E L   C  +     + C    + +  T +   CH C DH   P    C E
Sbjct: 322 HECLPCNCSGRS----EECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE 369



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 11/23 (47%), Positives = 14/23 (60%)

Query: 110 RCNPGTGQCVCPAGWVGEQCQHC 132
           +C+P TGQC C  G  G+ C  C
Sbjct: 928 QCHPKTGQCTCRPGVTGQACDRC 950



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 12/28 (42%), Positives = 14/28 (50%)

Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQHC 132
           C   G C+P TG CVC     G  C+ C
Sbjct: 709 CNQHGTCDPNTGICVCSHHTEGPSCERC 736


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 21/158 (13%)

Query: 100 EC-DRPCVNGGRCNPGTGQ--CVCPAGWVGEQCQH----CGGRFR-LTGSSGFVTDGPGN 151
           EC   PC+NGG C  G     C C   W G  CQ     CG     + GS  + +   G 
Sbjct: 435 ECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFSYRSPDVG- 493

Query: 152 YKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIV 207
           Y +   C W+I+ +  +++R+ F  F  E    C  + L VYDGDS  A  +  F G  +
Sbjct: 494 YVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSL 553

Query: 208 PERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
           P         E++++      H +S+   N  GF + +
Sbjct: 554 PH--------ELLSSDNALYFHLYSEHLRNGRGFTVRW 583



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 23/138 (16%)

Query: 130  QHCGGRFRLTGSSGFV----TDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----- 180
            Q CGG   LTGS+       +D  G Y     C W+I    N+++ L FN FA E     
Sbjct: 3155 QGCGGY--LTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTR 3212

Query: 181  --CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNL 238
              C +D++ +YDGDS  A L   F G  VP           +++  +  + F SD     
Sbjct: 3213 QRCLYDYVKLYDGDSENANLAGTFCGSTVP--------APFISSGNFLTVQFISDLTLER 3264

Query: 239  TGFNITYSFDMCPNNCSG 256
             GFN TY+    P  C G
Sbjct: 3265 EGFNATYTIMDMP--CGG 3280



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 40/135 (29%), Positives = 58/135 (42%), Gaps = 16/135 (11%)

Query: 128 QCQHCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----C 181
           Q   CGG   LTG  G +     PGNY     C W++   P+ ++   F   + E    C
Sbjct: 586 QQPECGGI--LTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDC 643

Query: 182 SWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241
           + D+L + DG     PL+  F            +VP +  T  +A +HF SD+  +  GF
Sbjct: 644 NKDYLEIRDGPLYQDPLLGKFCTTF--------SVPPLQTTGPFARIHFHSDSQISDQGF 695

Query: 242 NITYSFDMCPNNCSG 256
           +ITY        C G
Sbjct: 696 HITYLTSPSDLRCGG 710



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 18/123 (14%)

Query: 130  QHCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQP--NRIMRLRFNHF----ATEC 181
            Q CGG   LT S   V+    P NY     C+W+I+ QP  N I  L F HF    +T C
Sbjct: 1618 QACGGHI-LTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHI-TLSFTHFELERSTTC 1675

Query: 182  SWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241
            + D + + DG    APL   + G  +P          + + S    L F SD++ +  GF
Sbjct: 1676 ARDFVEILDGGHEDAPLRGRYCGTDMPH--------PITSFSSALTLRFVSDSSISAGGF 1727

Query: 242  NIT 244
            + T
Sbjct: 1728 HTT 1730



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 18/133 (13%)

Query: 132  CGGRFRLTGSSGFVTDGP---GNYKYKTKCTWLIEGQPNRIMRLRFNHF----ATECSWD 184
            CGG F    SSG +T       +Y     C + I    ++++ L+F+ F    +T CS D
Sbjct: 3037 CGGVFNF--SSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHD 3094

Query: 185  HLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT 244
            +L +YDG +   PL+  F         G++  P V +++   LL F +D+     G+ ++
Sbjct: 3095 YLAIYDGANTSDPLLGKFC--------GSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3146

Query: 245  YSFDMCP-NNCSG 256
            +   + P   C G
Sbjct: 3147 FRQTLGPQQGCGG 3159



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 35/121 (28%), Positives = 54/121 (44%), Gaps = 17/121 (14%)

Query: 132  CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWD 184
            CGG  R TG +      PG   +Y  +  CTWLI+  P+  + L       E    C++D
Sbjct: 1978 CGGFLR-TGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYD 2035

Query: 185  HLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT 244
             L + DGD+  A  +A   G  +P          + +T  Y  + F SD++    GFN +
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIP--------GPIRSTGEYMFIRFTSDSSVTRAGFNAS 2087

Query: 245  Y 245
            +
Sbjct: 2088 F 2088



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 17/132 (12%)

Query: 132  CGGRFRLTGSSG-FVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDH 185
            CGG   L+G++G F + G P  Y    +C W I   P   ++L  + F  E    C++D 
Sbjct: 1391 CGGE--LSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDV 1448

Query: 186  LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNIT 244
            L +Y G   ++P +A       PE       P  V+++G  L + F +D + N  GFN  
Sbjct: 1449 LEIYGGPDFHSPRIAQLCTQRSPEN------PMQVSSTGNELAIRFKTDLSINGRGFNA- 1501

Query: 245  YSFDMCPNNCSG 256
             S+      C G
Sbjct: 1502 -SWQAVTGGCGG 1512



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 15/120 (12%)

Query: 132  CGGRFRLTGSSG-FVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFAT----ECSWDH 185
            CGG   L G  G F + G PG Y   T C W++     R++ + F   +     +C  ++
Sbjct: 3511 CGGT--LYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNY 3568

Query: 186  LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            L +YDG +  +P    + G       G+ ++   VA+S    + F +D A   + F +T+
Sbjct: 3569 LTLYDGPNASSPSSGPYCG-------GDTSIAPFVASSNQVFIKFHADYARRPSAFRLTW 3621



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 16/114 (14%)

Query: 138  LTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDG 191
            LT S+G +     P  Y +   CTW I  QPN ++ L F  F  E    C+ D+L VYD 
Sbjct: 936  LTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDT 995

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            DS     +  + G  +P        P + ++    +L F +D+     GF I Y
Sbjct: 996  DS--ETSLGRYCGKSIP--------PSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 19/136 (13%)

Query: 132  CGGRFRL--TGSSGFVT--DGPGNYKYKTKCTWLIEGQPNRIMRLRFN-----HFATECS 182
            CGG   +    S+G+VT  + P NY     C W++   P   ++L+F           C+
Sbjct: 2217 CGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCT 2276

Query: 183  WDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGF 241
             ++L + DG    AP+++ F G  +P             +SG  + L F SD +    GF
Sbjct: 2277 SNYLELRDGVDSDAPILSKFCGTSLPSSQW---------SSGEVMYLRFRSDNSPTHVGF 2327

Query: 242  NITYSFDMCPNNCSGR 257
               YS   C     G+
Sbjct: 2328 KAKYSIAQCGGRVPGQ 2343



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 36/180 (20%)

Query: 96   AEAKECDRPCVNGGRCNPGTGQCVCPA---------------GWVGEQCQHCGGRFRLTG 140
            A  +E D+  +  G  N   G  + P+               G+       CG  F  TG
Sbjct: 2869 AGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQGFSASFVSRCGSNF--TG 2926

Query: 141  SSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE--------CSWDHLYVYD 190
             SG++     P  Y     CT++IE  P  ++ L F  F  E        C  D +++  
Sbjct: 2927 PSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIR 2986

Query: 191  GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250
            G S+ +   A   G         + +P  +  +G  LL+F+S+      GF  +Y    C
Sbjct: 2987 GYSVMSTPFATVCG---------DEMPAPLTIAGPVLLNFYSNEQITDFGFKFSYRIISC 3037



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 10/112 (8%)

Query: 216 VPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNN-CSGRGECKISNSSDTVECECS 274
           +P+ +++  Y L     D      G   T    +C +N C   G C   N  D+  C C 
Sbjct: 102 LPQNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCL--NLHDSFFCICP 159

Query: 275 ENWKGEAC--DIPHCTDNCGFP----HRGIC-NSSDVRGCSCFSDWQGPGCS 319
             WKG  C  D+  C    G P    + G C N+     C C  +  GP C+
Sbjct: 160 PQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCA 211



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 16/121 (13%)

Query: 132  CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDH 185
            CGG     G SG +T    P  Y   T C+ L+E      + L F+ F  E    C+WD 
Sbjct: 2689 CGGI--QIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDS 2746

Query: 186  LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
            + V +G S  +P++  +         GN     + + S   ++ F SD +    GF  T+
Sbjct: 2747 VTVRNGGSPESPIIGQYC--------GNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATW 2798

Query: 246  S 246
            +
Sbjct: 2799 N 2799



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 18/121 (14%)

Query: 132  CGGRFRLTGSSG-FVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDH 185
            CGG   LT SSG F++   P  Y + ++C W ++        L F  F  E    C+ D+
Sbjct: 1165 CGGN--LTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDY 1222

Query: 186  LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNIT 244
            L VYDG S  + L+    G         +  P ++ +SG ++ +   +D      GF   
Sbjct: 1223 LAVYDGPSSNSHLLTQLCG---------DEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAE 1273

Query: 245  Y 245
            Y
Sbjct: 1274 Y 1274



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 17/138 (12%)

Query: 122  AGWVGEQCQHCGGRFRLTGSSGFVT---DGPGNYKYKTKCTWLIEG--QPNRIMRLRFNH 176
            A +   +   CGG    T    F +   DG  NY     C W +    Q N  + + F  
Sbjct: 2560 ASYTSSEDAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFED 2619

Query: 177  FATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFS 232
            F  E    C +D L    GD+   PL+    G   P      T+P V+  S    +HF +
Sbjct: 2620 FYLESHQDCQFDVLEFRVGDAD-GPLMWRLCGPSKP------TLPLVIPYS-QVWIHFVT 2671

Query: 233  DAAYNLTGFNITYSFDMC 250
            +      GF+  YSF  C
Sbjct: 2672 NERVEHIGFHAKYSFTDC 2689



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 22/133 (16%)

Query: 132  CGGRFRLTGSSGFVTD-GPGNYKYKTK--CTWLIEGQPNRIMRLRFNHF----ATECSWD 184
            CGGR  + G SG V   G     Y+    C W ++G     + + F  F    ++ C  D
Sbjct: 2336 CGGR--VPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKD 2393

Query: 185  HLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGY-ALLHFFSDAAYNLTGFNI 243
             + ++D  +         SG I+    GN T+P+ + TS   A++ F +D +   +GF +
Sbjct: 2394 FVEIWDNHT---------SGNILGRYCGN-TIPDSIDTSSNTAVVRFVTDGSVTASGFRL 2443

Query: 244  TYSFDMCPNNCSG 256
             +   M    C G
Sbjct: 2444 RFESSM--EECGG 2454



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 5/77 (6%)

Query: 230 FFSDAAYNLTGFNITYSFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEACDIPHCT 288
           +F       TG N T + + C +N C   G C   +  D+  CEC+  W G  C +P   
Sbjct: 416 YFCKCDSGWTGVNCTENINECLSNPCLNGGTCV--DGVDSFSCECTRLWTGALCQVPQ-- 471

Query: 289 DNCGFPHRGICNSSDVR 305
             CG    GI  S   R
Sbjct: 472 QVCGESLSGINGSFSYR 488



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 14/112 (12%)

Query: 149  PGNYKYKTKCTWLIEGQPNRIMRLRFNHF----ATECSWDHLYVYDGDSIYAPLVAAFSG 204
            P NY     CT  +    N  + L F+      + EC  D L V +G +  +PL+  + G
Sbjct: 3412 PDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCG 3471

Query: 205  LIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSG 256
             ++P          V + +    L F SD+  +  G+ I ++    P+ C G
Sbjct: 3472 TLLPN--------PVFSQNNELYLRFKSDSVTSDRGYEIIWT--SSPSGCGG 3513



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 24/131 (18%), Positives = 53/131 (40%), Gaps = 17/131 (12%)

Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATEC----SWDHLY 187
           CGG +       F+ +  G + +  +C ++++      +++ F H   +C    S +++ 
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767

Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSF 247
           V DG+++   +             GN T+  + + +    + F  DA+     F   Y  
Sbjct: 768 VRDGETLLGKVC------------GNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 815

Query: 248 DMCPNNCSGRG 258
             C +  +G G
Sbjct: 816 -ACGDELTGEG 825



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 9/115 (7%)

Query: 132  CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191
            CGG F+         + P  Y+  T C+W+I    N  + L F  F  E     +  YDG
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMAYDG 1569

Query: 192  DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNITY 245
                  L +  S L      G E +   + +SG +L L F S  +    GF   +
Sbjct: 1570 ------LSSTMSRL--ARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 20/67 (29%), Positives = 23/67 (34%), Gaps = 5/67 (7%)

Query: 260 CKISNSSDTVE---CECSENWKGEAC--DIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQ 314
           C      DTV    C+C   W G  C  +I  C  N         +  D   C C   W 
Sbjct: 404 CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWT 463

Query: 315 GPGCSVP 321
           G  C VP
Sbjct: 464 GALCQVP 470


>gi|50659100 regeneration associated muscle protease isoform b [Homo
           sapiens]
          Length = 720

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 47/181 (25%), Positives = 74/181 (40%), Gaps = 19/181 (10%)

Query: 120 CPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFAT 179
           C AGW G  C  CG   R       +     +Y     C W I  +P  +++LRF   + 
Sbjct: 116 CRAGWYGGDCMRCGQVLRAPKGQILLE----SYPLNAHCEWTIHAKPGFVIQLRFVMLSL 171

Query: 180 E----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAA 235
           E    C +D++ V DGD+          G I+    GNE    + +      + F SD +
Sbjct: 172 EFDYMCQYDYVEVRDGDN--------RDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGS 223

Query: 236 YNLTGFNITY-SFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGF 293
            N  GF+  Y     C ++ C   G C + + + + +C C   + G+ C+      NC  
Sbjct: 224 KNFDGFHAIYEEITACSSSPCFHDGTC-VLDKAGSYKCACLAGYTGQRCENLLEERNCSD 282

Query: 294 P 294
           P
Sbjct: 283 P 283


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 9/88 (10%)

Query: 1059 HCPACQCNGHSKCINQSI--CEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGH 1114
            HC  C+CNGHS   +     C +C++   G+ CE C  G+YGD T G    CQPC C   
Sbjct: 1559 HCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC--- 1615

Query: 1115 ASLCN-TNTGKCFCTTKGVKGDECQLCE 1141
              L N  N     C + G  G  C  CE
Sbjct: 1616 -PLTNPENMFSRTCESLGAGGYRCTACE 1642



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 15/107 (14%)

Query: 1060 CPACQCNGHSKCINQSI--CEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGH- 1114
            C  C C+GHS+        C+ C++ T G  CE C  G+YGD   G    CQ C C G  
Sbjct: 1156 CERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDP 1215

Query: 1115 -----ASLCNTNTG---KCFCTTKGVKGDECQLCEVENRYQGNPLRG 1153
                 A  C  +T     C   + G  G  C+ C     Y GNP +G
Sbjct: 1216 AAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERC--APGYYGNPSQG 1260



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 1079 KCENLTTGKHCETCISGFY--GDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDE 1136
            +C     G  C+ C  G+   G     G C+ C+CNGH+ LC+  TG C        G+ 
Sbjct: 1531 RCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEF 1590

Query: 1137 CQLCEVENRYQGNPLRGT 1154
            C+LC     Y G+   GT
Sbjct: 1591 CELC--APGYYGDATAGT 1606



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 58/227 (25%), Positives = 89/227 (39%), Gaps = 56/227 (24%)

Query: 924  HSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCP 983
            HS ++CR P           SG S          C   +A+    P G  +      TC 
Sbjct: 726  HSVEECRCPIGY--------SGLS----------CESCDAHFTRVPGGPYL-----GTCS 762

Query: 984  PENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFYPQ 1039
              NC+G+   S C   P  G C +  +  +G    KC  G +   +K  + A +    P 
Sbjct: 763  GCNCNGHA--SSC--DPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMK--ATATSCRPCPC 816

Query: 1040 PLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGD 1099
            P +++S    D+ +            +G      Q+ C+ C    TG+ CE+C  G+ G+
Sbjct: 817  PYIDASRRFSDTCF---------LDTDG------QATCDACAPGYTGRRCESCAPGYEGN 861

Query: 1100 PTN-GGKCQP-----CKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140
            P   GGKC+P      +C+   S+  T+   C C    V G  C  C
Sbjct: 862  PIQPGGKCRPVNQEIVRCDERGSM-GTSGEACRC-KNNVVGRLCNEC 906



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 56/230 (24%), Positives = 76/230 (33%), Gaps = 62/230 (26%)

Query: 927  KQCRTPCALR-TACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPE 985
            +QC  P   R  +C DC +G +             S  Y+ +    +C        C PE
Sbjct: 1124 EQCSCPPGYRGPSCQDCDTGYTR----------TPSGLYLGTCE--RCSCHGHSEACEPE 1171

Query: 986  N--CSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKM--PSQAPTGNFYPQPL 1041
               C G   C H  E P C  C            +  Y G  +   P        Y  P 
Sbjct: 1172 TGACQG---CQHHTEGPRCEQC------------QPGYYGDAQRGTPQDCQLCPCYGDPA 1216

Query: 1042 LNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPT 1101
               +             H      +GH  C      + C    +G+HCE C  G+YG+P+
Sbjct: 1217 AGQAA------------HTCFLDTDGHPTC------DACSPGHSGRHCERCAPGYYGNPS 1258

Query: 1102 NGGKCQ-------PCKCN----GHASLCNTNTGKCFCTTKGVKGDECQLC 1140
             G  CQ       P  CN    G  S      G+C C  + V+G  C  C
Sbjct: 1259 QGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQ-VEGLTCSHC 1307



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1086 GKHCETCISGFYGDPTNG--GKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVE 1143
            G  C+ C +G+   P+    G C+ C C+GH+  C   TG C       +G  C+ C  +
Sbjct: 1134 GPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQC--Q 1191

Query: 1144 NRYQGNPLRGT 1154
              Y G+  RGT
Sbjct: 1192 PGYYGDAQRGT 1202



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 1079 KCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDE 1136
            +C    +G  CE+C + F   P     G C  C CNGHAS C+   G C       +G +
Sbjct: 732  RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQ 791

Query: 1137 CQLCE 1141
            C  C+
Sbjct: 792  CNKCK 796



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 3/33 (9%)

Query: 102  DRPCVNGGRCNPGTGQ---CVCPAGWVGEQCQH 131
            DRPC NGG+C+        CVCPAG+ G +C+H
Sbjct: 3850 DRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEH 3882



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 10/55 (18%)

Query: 104  PCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGR------FRLTGSSGFVTDGPGNY 152
            PC++GG C  GT +C+C  G+ G +CQ   G       + L GS G   D PG Y
Sbjct: 4152 PCLHGGTCQ-GT-RCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGG--NDAPGQY 4202



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)

Query: 1077 CEKCENLTTGKHCETCISGFYGDPT-NGGKCQP 1108
            C  CE   TG++CE C  G+ G+P+  GG+C P
Sbjct: 1638 CTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 4/76 (5%)

Query: 237  NLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACD---IPHCTDNCGF 293
            NLT   I++        C   G+C  S SS  V C C   + G  C+     HC      
Sbjct: 3836 NLTAHGISHCPTCRDRPCQNGGQCHDSESSSYV-CVCPAGFTGSRCEHSQALHCHPEACG 3894

Query: 294  PHRGICNSSDVRGCSC 309
            P     N  D RG +C
Sbjct: 3895 PDATCVNRPDGRGYTC 3910



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 55   PPLRPRLLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPG 114
            P  R  LL+ L  L   L+         A  ++  ++ S +A + E  +P  +       
Sbjct: 1475 PATREHLLMALADLDELLI--------RATFSSVPLAASISAVSLEVAQPGPSNRPRALE 1526

Query: 115  TGQCVCPAGWVGEQCQHCGGRFRLTGS 141
              +C CP G++G  CQ C   +  TGS
Sbjct: 1527 VEECRCPPGYIGLSCQDCAPGYTRTGS 1553



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 97   EAKECDR-PCVNGGRCNPGTG---QCVCPAGWVGEQCQH 131
            ++  C+R PC +G  C P      QC+C  G+ G+ C+H
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEH 4142


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,727,572
Number of Sequences: 37866
Number of extensions: 2901887
Number of successful extensions: 12250
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 372
Number of HSP's that attempted gapping in prelim test: 8132
Number of HSP's gapped (non-prelim): 3417
length of query: 1272
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1158
effective length of database: 13,930,794
effective search space: 16131859452
effective search space used: 16131859452
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.