BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21450861 attractin isoform 1 [Homo sapiens] (1429 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21450861 attractin isoform 1 [Homo sapiens] 3051 0.0 gi|21450863 attractin isoform 2 [Homo sapiens] 2733 0.0 gi|46410931 attractin-like 1 [Homo sapiens] 1771 0.0 gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 213 1e-54 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 79 3e-14 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 77 9e-14 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 77 9e-14 gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 75 5e-13 gi|119703755 laminin, beta 2 precursor [Homo sapiens] 74 8e-13 gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 73 2e-12 gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 73 2e-12 gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 73 2e-12 gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 73 2e-12 gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 72 3e-12 gi|143770880 laminin, beta 4 [Homo sapiens] 72 4e-12 gi|22547221 tolloid-like 1 [Homo sapiens] 72 4e-12 gi|6912724 tolloid-like 2 [Homo sapiens] 71 9e-12 gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 70 1e-11 gi|219842266 usherin isoform B [Homo sapiens] 69 2e-11 gi|219842259 usherin isoform A [Homo sapiens] 69 2e-11 gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 69 3e-11 gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 68 7e-11 gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 68 7e-11 gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 68 7e-11 gi|16945972 kelch domain containing 3 [Homo sapiens] 68 7e-11 gi|164414431 netrin G1 isoform 1 [Homo sapiens] 67 2e-10 gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 67 2e-10 gi|126091152 cubilin [Homo sapiens] 66 2e-10 gi|50659100 regeneration associated muscle protease isoform b [H... 66 2e-10 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 65 5e-10 >gi|21450861 attractin isoform 1 [Homo sapiens] Length = 1429 Score = 3051 bits (7910), Expect = 0.0 Identities = 1429/1429 (100%), Positives = 1429/1429 (100%) Query: 1 MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60 MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR Sbjct: 1 MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60 Query: 61 LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120 LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC Sbjct: 61 LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120 Query: 121 PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180 PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE Sbjct: 121 PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180 Query: 181 CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240 CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG Sbjct: 181 CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240 Query: 241 FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300 FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN Sbjct: 241 FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300 Query: 301 SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360 SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM Sbjct: 301 SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360 Query: 361 FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420 FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE Sbjct: 361 FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420 Query: 421 LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480 LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY Sbjct: 421 LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480 Query: 481 DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540 DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD Sbjct: 481 DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540 Query: 541 TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600 TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW Sbjct: 541 TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600 Query: 601 SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660 SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA Sbjct: 601 SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660 Query: 661 GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720 GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC Sbjct: 661 GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720 Query: 721 HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780 HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC Sbjct: 721 HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780 Query: 781 IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840 IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR Sbjct: 781 IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840 Query: 841 IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900 IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS Sbjct: 841 IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900 Query: 901 TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960 TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD Sbjct: 901 TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960 Query: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS Sbjct: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020 Query: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC Sbjct: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080 Query: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC Sbjct: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140 Query: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS Sbjct: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200 Query: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF Sbjct: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260 Query: 1261 TWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREM 1320 TWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREM Sbjct: 1261 TWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREM 1320 Query: 1321 QQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLG 1380 QQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLG Sbjct: 1321 QQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLG 1380 Query: 1381 GIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI 1429 GIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI Sbjct: 1381 GIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI 1429 >gi|21450863 attractin isoform 2 [Homo sapiens] Length = 1272 Score = 2733 bits (7084), Expect = 0.0 Identities = 1268/1272 (99%), Positives = 1269/1272 (99%) Query: 1 MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60 MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR Sbjct: 1 MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR 60 Query: 61 LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120 LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC Sbjct: 61 LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC 120 Query: 121 PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180 PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE Sbjct: 121 PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE 180 Query: 181 CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240 CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG Sbjct: 181 CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG 240 Query: 241 FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300 FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN Sbjct: 241 FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN 300 Query: 301 SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360 SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM Sbjct: 301 SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM 360 Query: 361 FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420 FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE Sbjct: 361 FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE 420 Query: 421 LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480 LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY Sbjct: 421 LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY 480 Query: 481 DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540 DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD Sbjct: 481 DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD 540 Query: 541 TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600 TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW Sbjct: 541 TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW 600 Query: 601 SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660 SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA Sbjct: 601 SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA 660 Query: 661 GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720 GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC Sbjct: 661 GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC 720 Query: 721 HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780 HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC Sbjct: 721 HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC 780 Query: 781 IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840 IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR Sbjct: 781 IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR 840 Query: 841 IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900 IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS Sbjct: 841 IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS 900 Query: 901 TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960 TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD Sbjct: 901 TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD 960 Query: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS Sbjct: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS 1020 Query: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC Sbjct: 1021 YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC 1080 Query: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC Sbjct: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140 Query: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS Sbjct: 1141 EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS 1200 Query: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF Sbjct: 1201 KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF 1260 Query: 1261 TWPIKIQIAFSQ 1272 TWPIKIQ+ Q Sbjct: 1261 TWPIKIQVQTEQ 1272 >gi|46410931 attractin-like 1 [Homo sapiens] Length = 1379 Score = 1771 bits (4586), Expect = 0.0 Identities = 818/1341 (60%), Positives = 1021/1341 (76%), Gaps = 36/1341 (2%) Query: 103 RPCVNGGRCNPG---TGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCT 159 +PC G C G C+C GWVG+QCQHC GRF+LT SG++TDGP NYKYKTKCT Sbjct: 61 KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT 120 Query: 160 WLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEV 219 WLIEG PN ++RLRFNHFATECSWDH+YVYDGDSIYAPL+A SGLIVPE GNETVPEV Sbjct: 121 WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV 180 Query: 220 VATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDT-VECECSENWK 278 V TSGYALLHFFSDAAYNLTGFNI YS + CPNNCSG G+C S S + V CEC + WK Sbjct: 181 VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK 240 Query: 279 GEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338 GEACDIP+C NCG P G C+ + + C C WQGP CS+ VP+ +S+W Sbjct: 241 GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS 300 Query: 339 --LPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHS 396 + RASHKAV++G MWV+GGY FN+S + MVL Y+L S W + + RYGHS Sbjct: 301 PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIW-NVGTPSRGPLQRYGHS 359 Query: 397 LALYKDKIYMYGGKIDST-GNVTNELRVFHIHNESWVLLTPKAK---EQYAVVGHSAHIV 452 LALY++ I+MYGG+I++ GNVT+EL VF+IH++SW TP +QYAV GHSAHI+ Sbjct: 360 LALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIM 419 Query: 453 TLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTR 512 L + VVM++IFG+ +YGY S++QEY + NTW + T+GA+VQGGYGH+SVYD T+ Sbjct: 420 ELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITK 479 Query: 513 ALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGN 572 ++YVHGGYKA NKY L DDLY+Y+V+T+ WTILK+S F RYLH+AV+++G ML+FGGN Sbjct: 480 SIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGN 539 Query: 573 THNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF 632 THNDTS+S+GAKCFS+DF+AYDIACD W +LP+P+LH DVNRFGHSAV+ N +MY+FGGF Sbjct: 540 THNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF 599 Query: 633 NSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSE 692 +S+LL+DILV+ C A R E C AGPGI+CVWN + C SW + L+++ Sbjct: 600 SSVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWN--KNHCESWE--SGNTNNILRAK 655 Query: 693 CFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDH-CVPRNHSCSEGQISIFRYENCPKDN 751 C K DRC ++ DC SCTANTN C WC+D C+ N +CS +S+ Y C N Sbjct: 656 CPPKTAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCS---MSVKNYTKCHVRN 712 Query: 752 PMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDN 811 CNK TSC+SC+L+ NCQW+ R QEC ALP ++CG GW +G++CL++ +++ENYDN Sbjct: 713 EQI-CNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDN 771 Query: 812 AKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWED 871 AKL+C N + LASLTT K+VEFVL ++ Q ++ ++PWVGLRKIN+SYW WED Sbjct: 772 AKLYCYNLSGNLASLTTSKEVEFVLDEI------QKYTQQKVSPWVGLRKINISYWGWED 825 Query: 872 MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQ 928 MSPFTN+ LQW+P EP+D+GFC L + GLKA C + NG VCE+P N +A+ Sbjct: 826 MSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARP 885 Query: 929 CRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS 988 C+ PC+LRT+C +CTS ECMWCS+ K+CVDSNAY+ SFP+GQC+EW T +TC P+NCS Sbjct: 886 CKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQT-ATCSPQNCS 944 Query: 989 GYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCL 1048 G TC CLEQPGCGWC DPSNTG+G CIEGS +GP+K+ G + + +L++++C Sbjct: 945 GLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKL-----IGMHHSEMVLDTNLCP 999 Query: 1049 EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQP 1108 ++ Y WSFI CPACQCNGHS CIN ++CE+C+NLTTGK C+ C+ G+YGDPTNGG+C Sbjct: 1000 KEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTA 1059 Query: 1109 CKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFS 1168 C C+GHA++C+ +TGKCFCTTKG+KGD+CQLC+ ENRY GNPLRGTCYY+LLIDYQFTFS Sbjct: 1060 CTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFS 1119 Query: 1169 LSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSK 1228 L QEDDR++TAINF+A P++ N++LD+ INAS NFNLNITW+ +AGT +GEE +VSK Sbjct: 1120 LLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSK 1179 Query: 1229 TNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFS 1288 NIKEY+DSFS EKF+FR++PNITF+VYVSNF+WPIKIQIAFSQH+ MDLVQFFVTFFS Sbjct: 1180 NNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFS 1239 Query: 1289 CFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGS 1348 CFLSLLLVAAVVWKIKQ+CWASRRREQLLRE QQMASRPFASV+VALE E + + G Sbjct: 1240 CFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRGP 1299 Query: 1349 IKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYK 1408 ++ PKPIA+EPC GN+AAVL+VF+ LPRG G PPPGQSGLA+ASAL+DISQQ K Sbjct: 1300 LEGAPKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKASDSK 1359 Query: 1409 EKSGAVRNRKQQPPAQPGTCI 1429 +K+ VRNRK Q GTC+ Sbjct: 1360 DKTSGVRNRKHLSTRQ-GTCV 1379 >gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] Length = 2778 Score = 213 bits (542), Expect = 1e-54 Identities = 159/536 (29%), Positives = 239/536 (44%), Gaps = 49/536 (9%) Query: 133 GGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYVYDG 191 G R L + GFVTDG GNY C WLIE P + L F TEC++D+L+VYDG Sbjct: 32 GQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDG 91 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCP 251 DS PL+A+ SG P P + A+SG LLH FSDA YNL GFN ++ F +CP Sbjct: 92 DSPRGPLLASLSGSTRP--------PPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCP 143 Query: 252 NNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFS 311 C G+C+ C C W G C + C+ CG G C +S + C C Sbjct: 144 GGCQSHGQCQPPG-----VCACEPGWGGPDCGLQECSAYCG--SHGTC-ASPLGPCRCEP 195 Query: 312 DWQGPGCSVPVPANQ--SFW----TREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSD 365 + G C + + NQ +W R+ + ++ A G ++ V GG N++ Sbjct: 196 GFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG-LLAVFGGQDLNNAL 254 Query: 366 YNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFH 425 ++VL Y+ ++ W + S R+ H + + + GG++ + G++TN++ F Sbjct: 255 GDLVL-YNFSANTWESWDLS-PAPAARHSHVAVAWAGSLVLMGGEL-ADGSLTNDVWAFS 311 Query: 426 -IHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDK 484 + W LL P A G + H L + V + V G P + S + + LD Sbjct: 312 PLGRGHWELLAPPASSSSGPPGLAGHAAALVDD-VWLYVSGGRTPHDLFSSGLFRFRLDS 370 Query: 485 NT---WSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDT 541 + W + G GHS V+ +RAL VHGG++ +A + + VD Sbjct: 371 TSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDR 430 Query: 542 QMWTILKDSRFF-----RYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIA 596 +WT LK R HTA ++ M+V+GGN H KC+ Y + Sbjct: 431 HVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEE---KCYEDGIFFYHLG 487 Query: 597 CDRW--------SVLPRPDLHHDVNRFGH-SAVLHNSTMYVFGGFNSLLLSDILVF 643 C +W P R+ H +AVL S + V GG++ D++ + Sbjct: 488 CHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAY 543 Score = 143 bits (361), Expect = 1e-33 Identities = 198/836 (23%), Positives = 298/836 (35%), Gaps = 197/836 (23%) Query: 103 RPC-VNG------GRCNPGTGQCVCPAGWVGEQCQ------------------HCGGRFR 137 RPC NG G C+ +G C C G CQ CGGR Sbjct: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL 1201 Query: 138 LTGSS-----------------GFVTDGPGNYKYKTKCTWLIEGQ-------PNRI---M 170 LT S G GPG + C W++ P + + Sbjct: 1202 LTNVSSVALGSRRVGGLLPPGGGAARAGPG----LSYCVWVVSATEELQPCAPGTLCPPL 1257 Query: 171 RLRFN-HFATECSWDHLYVYDGDSIYAP---------LVAAFSGLIVPERDGNETVPEVV 220 L F+ +T C+ ++ +DG + L+AAF G RD TV Sbjct: 1258 TLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCG---QRRDRPLTVQ--- 1311 Query: 221 ATSGYALLHFFSDAAYNLTGFNITYSFDMC----PNNCSGRGECKISNSSDTVE-CECSE 275 A SG +LH+ ++ + + GFN + C P +C EC + + C C + Sbjct: 1312 ALSGLLVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQ 1370 Query: 276 NWKGEACDIPHCTDNCG-FPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEY 334 W G C + C +NC G CN S + C C + GP C+ + Q W Sbjct: 1371 GWAGPHCRMALCPENCNAHTGAGTCNQS-LGVCICAEGFGGPDCATKLDGGQLVWETLMD 1429 Query: 335 SNLKLPRASH------KAVVNGN--IMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSV 386 S L AS +V+G +W+ GG + Y ++ R W + Sbjct: 1430 SRLSADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGA 1489 Query: 387 NN----VVVRYGHSLALY---KDKIYMYGGKIDSTGNVTNELRVFHIHNESWVL-LTPKA 438 + R H+ A + +Y+ GG + G VT + V ++ W P+ Sbjct: 1490 EDGGPGPSPRSFHAAAYVPAGRGAMYLLGGL--TAGGVTRDFWVLNLTTLQWRQEKAPQT 1547 Query: 439 KEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQ 498 E AV GH+ +T + G + +L++ G+ P G+ + EY L TW G Sbjct: 1548 VELPAVAGHT---LTARRG-LSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPT 1603 Query: 499 GGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSR------- 551 G YGHS+VY T +LYV GG++ F + +LY + W++L S+ Sbjct: 1604 GLYGHSAVYHEATDSLYVFGGFR-FHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRM 1662 Query: 552 ---------------------FFRYLHTAVIVSGTMLVFGG-----NTH----------- 574 FR + + + + GG + H Sbjct: 1663 RNVRGSSRGLGQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHA 1722 Query: 575 ----NDTSMSHGAKC----FSSDFMAYDIACDRWSVLPRPDLHHDVN-------RFGHSA 619 DT + G + FSSD + Y + C+ W + PDL + H+ Sbjct: 1723 SALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLL---PDLTRSASVGPPMEESVAHAV 1779 Query: 620 VLHNSTMYVFGGFNSLLLSDILVFT--SEQCDAHRSEAACLAAGPGIRCVW--------- 668 S +Y+ GGF + L +L T + C S AC +G C W Sbjct: 1780 AAVGSRLYISGGFGGVALGRLLALTLPPDPCRLLSSPEACNQSG---ACTWCHGACLSGD 1836 Query: 669 -----NTGSSQCISWALATDE-QEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHW 722 G S C + +E + + SEC ++ H R Q D A+T C W Sbjct: 1837 QAHRLGCGGSPCSPMPRSPEECRRLRTCSECLAR----HPRTLQPGD---GEASTPRCKW 1889 Query: 723 CND----HCVPRNHSC-SEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQW 773 C + C+ RN SC SE I + E N C C + C W Sbjct: 1890 CTNCPEGACIGRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMW 1945 Score = 97.1 bits (240), Expect = 1e-19 Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 27/190 (14%) Query: 920 RPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTM 979 R A S ++C C+ R C DC + SS+C WC + C AY+A +P G C W Sbjct: 870 RGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDS 929 Query: 980 STCPP--ENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFY 1037 P +C G+ TC CL+ CGWC + N G+C++G + GP+ + + Sbjct: 930 VHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPL----GGGNCSLW 985 Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCP--------ACQCNGHSKCINQSICEKCENLTTGKHC 1089 L + L W++ CP +C+ + C+N + +C HC Sbjct: 986 VGEGLGLPVALP---ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC-------HC 1035 Query: 1090 ETCISGFYGD 1099 + G+ GD Sbjct: 1036 Q---RGYQGD 1042 Score = 95.5 bits (236), Expect = 3e-19 Identities = 77/284 (27%), Positives = 107/284 (37%), Gaps = 78/284 (27%) Query: 908 TCINPLNGSVCERPANHSAK-QCRTPCALRTACGDCTS------GSSECMWCSNMKQCVD 960 TC + +V P S C TPC L C C G C+W S+++QC+ Sbjct: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027 Query: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCT----CSHCLEQPGCGWCTDPSNTGKGKC 1016 + G C PE+CS C C+ CL +P CGWC G G+C Sbjct: 2028 PSYLPLRCMAGGCGRLLR----GPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRC 2083 Query: 1017 IEGSYKGP---------------VKMPSQ----------APTGNFYPQP----------- 1040 +EG GP + P + T N + QP Sbjct: 2084 MEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGY 2143 Query: 1041 ----------------LLNSSMCLEDS--RYNWSFI--HCPA-CQCNGHSKCIN---QSI 1076 +N S C+E R ++ F+ +C C+CN HS+C + Sbjct: 2144 TMDNMTGLCRPVCAQGCVNGS-CVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDH 2202 Query: 1077 CEKCENLTTGKHCETCISGFYGDPTNGGKCQPCK--CNGHASLC 1118 C C N T G HCE C+ F G GG C+PC C G++ +C Sbjct: 2203 CLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHIC 2246 Score = 83.6 bits (205), Expect = 1e-15 Identities = 77/292 (26%), Positives = 112/292 (38%), Gaps = 88/292 (30%) Query: 924 HSAKQCRTPCALRTACGDCTSGSSECMWCSN-----MKQCVDSNAYVASFPFGQCMEW-- 976 HS +CR+ C C +C S EC WC N + +C+ + + G C W Sbjct: 931 HSEPRCRS-CDGFLTCHECLQ-SHECGWCGNEDNPTLGRCLQGD-FSGPLGGGNCSLWVG 987 Query: 977 ------------YTMSTCPPEN--------CSGYCTC--------------------SHC 996 + + CP + C TC SHC Sbjct: 988 EGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC 1047 Query: 997 ----LEQPGCGWCTDPSNTGKGKCI-EGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDS 1051 LE G G C+ P + C+ + + + P+ AP P P C D Sbjct: 1048 NRTCLEDCGHGVCSGPPDF---TCVCDLGWTSDLPPPTPAPGP---PAP-----RCSRD- 1095 Query: 1052 RYNWSFIHCPACQCNGHSKCINQS--ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPC 1109 C C+ HS C + C++C++ T G+HCE C G +G+ T C+PC Sbjct: 1096 -----------CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144 Query: 1110 KCNGHA----SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNP-LRGTCY 1156 +CNGH C+ +G CFC +G CQLC Y G+P G+C+ Sbjct: 1145 QCNGHGDPRRGHCDNLSGLCFCQDH-TEGAHCQLC--SPGYYGDPRAGGSCF 1193 Score = 67.4 bits (163), Expect = 9e-11 Identities = 108/449 (24%), Positives = 162/449 (36%), Gaps = 105/449 (23%) Query: 704 CDQHTDCYSCTANTNDCHWCNDHCVPRNHSCS---EGQISIFRYENCPKDNPMYYCNKKT 760 C++H DC++CT + C W + +CS G+ ++ E CP C+++ Sbjct: 834 CEEHRDCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP-----LCSQRL 887 Query: 761 SCRSC-ALDQNCQWEPRNQECIAL-------PENICGIGWHLVGNSCLKITTAKENYDNA 812 +C C A C W C P C GW ++ ++ Sbjct: 888 TCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCR-GW--------------DDSVHS 932 Query: 813 KLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVG-LRKINVSYWCWED 871 + CR+ + LT + ++ + + ++ + + G L N S W E Sbjct: 933 EPRCRSCDGF---LTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEG 989 Query: 872 MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCIN-PLNGSV-CERP-ANHSAKQ 928 + +W + D C + R ATC+N PL+ C+R Sbjct: 990 LGLPVALPARWAYARCPDVDECRL---GLARCHPRATCLNTPLSYECHCQRGYQGDGISH 1046 Query: 929 CRTPCALRTACGDCTSGSSECMWCSNMKQ--CVDSNAYVASFPFGQCMEWYTMSTCPP-E 985 C RT DC G CS CV + + P T + PP Sbjct: 1047 CN-----RTCLEDCGHGV-----CSGPPDFTCVCDLGWTSDLPPP------TPAPGPPAP 1090 Query: 986 NCSGYCTC---SHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFYP 1038 CS C C SHC ++ G G+C + + G +C GS+ GN Sbjct: 1091 RCSRDCGCSFHSHCRKR-GPGFCDECQDWTWGEHCERCRPGSF------------GN--- 1134 Query: 1039 QPLLNSSMCLEDSRYNWSFIHCPACQCNGH-----SKCINQSICEKCENLTTGKHCETCI 1093 SR C CQCNGH C N S C++ T G HC+ C Sbjct: 1135 ---------ATGSR------GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCS 1179 Query: 1094 SGFYGDPTNGGKCQPCKCNGHASLCNTNT 1122 G+YGDP GG C +C G A L N ++ Sbjct: 1180 PGYYGDPRAGGSCFR-ECGGRALLTNVSS 1207 Score = 62.8 bits (151), Expect = 2e-09 Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 37/205 (18%) Query: 986 NCSGYCTCSHCLEQPGCG---WCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLL 1042 NCS C C+ E G G C N KG E P+ + S G P Sbjct: 2181 NCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCL--PLFVGSAVGGGTCRPCHAF 2238 Query: 1043 ---NSSMCL----------EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089 NS +C+ E +Y+ G S+ ++++C C+N + G+ C Sbjct: 2239 CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE--DEAVCVNCQNNSYGEKC 2296 Query: 1090 ETCISGFYGDPTNGGKCQPCKCNGHASLC------------NTNTGKCFCTTKGVKGD-- 1135 E+C+ G++ GKC C+CNGHA C NT TG C ++ + D Sbjct: 2297 ESCLQGYF---LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCY 2353 Query: 1136 ECQLCEVENRYQGNPLRGTCYYTLL 1160 + Q + + G+PL G Y L+ Sbjct: 2354 KYQCAKCRESFHGSPLGGQQCYRLI 2378 Score = 60.1 bits (144), Expect = 2e-08 Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 48/177 (27%) Query: 1270 FSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFA 1329 F Q +DL FF FFSCF L + ++WK KQ+ + + + L+EM +MASRPFA Sbjct: 2572 FRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFA 2631 Query: 1330 SVNVALETDEE-------------------------------------------PPDLIG 1346 V V D PP + Sbjct: 2632 KVTVCFPPDPTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPA 2691 Query: 1347 GSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQM 1403 + PI LEP A V ++ ++LP G P +G + SALV + ++ Sbjct: 2692 TTAGLRAGPITLEPTEDGMAGVATLLLQLPGG-----PHAPNGACLGSALVTLRHRL 2743 Score = 46.2 bits (108), Expect = 2e-04 Identities = 46/214 (21%), Positives = 65/214 (30%), Gaps = 52/214 (24%) Query: 933 CALRTACGDCTSGSSECMWCSNMKQCV--DSNAYVASFPFGQCMEWYTMSTCPPENCSGY 990 C ++C C + C WC C A+ G + + CP C + Sbjct: 781 CTSYSSCLGCLADQG-CGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPL--CEEH 837 Query: 991 CTCSHCLEQPGCGWCTDPSNTGKGKCIE-GSYKGPVKMPSQAPTGNFYPQPLLNSSMCLE 1049 C C + P C W S G C G +G +K P + P PL + + E Sbjct: 838 RDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECP-------PLCSQRLTCE 890 Query: 1050 DSRYNWSFIHCPACQ-------------------CNGHSKCIN-QSICEKCENLTTGKHC 1089 D N S C CQ C G ++ + C C+ T C Sbjct: 891 DCLANSS--QCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHEC 948 Query: 1090 -----------------ETCISGFYGDPTNGGKC 1106 C+ G + P GG C Sbjct: 949 LQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNC 982 Score = 38.1 bits (87), Expect = 0.061 Identities = 54/238 (22%), Positives = 76/238 (31%), Gaps = 44/238 (18%) Query: 915 GSVCERPANHSAKQCR-----TPCALR----TACGDCTSGSSECMWCSNMKQ--CVDSNA 963 GS C P S ++CR + C R GD + + C WC+N + C+ N Sbjct: 1845 GSPCS-PMPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNG 1903 Query: 964 YVASFPFGQCM----EWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGK---- 1015 S C E + C C G C C + C W TG+ + Sbjct: 1904 SCTSE--NDCRINQREVFWAGNCSEAAC-GAADCEQCTREGKCMWTRQFKRTGETRRILS 1960 Query: 1016 --------CIEGSYKGPVKMPSQAPTGNFYPQP---LLNSSMCLEDSRYNWSFIHC---- 1060 C S MP ++ P P L N + CL+ + + HC Sbjct: 1961 VQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSS 2020 Query: 1061 PACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLC 1118 QC S + + C L G E+C G +C C H C Sbjct: 2021 SLQQCLSPSYLPLRCMAGGCGRLLRGP--ESCSLGC----AQATQCALCLRRPHCGWC 2072 Score = 35.4 bits (80), Expect = 0.40 Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 969 PFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWC 1005 P G + ++ + +C+ Y +C CL GCGWC Sbjct: 763 PGGSEISFFFLEPYRSSSCTSYSSCLGCLADQGCGWC 799 Score = 32.3 bits (72), Expect = 3.4 Identities = 32/103 (31%), Positives = 38/103 (36%), Gaps = 29/103 (28%) Query: 932 PCALRTACGDCTSGSSECMWCSNMKQCVDSN-AYVASFPFGQCMEWYTMSTCP--PENCS 988 PC L ++ C S C WC C+ + A+ C S P PE C Sbjct: 1809 PCRLLSSPEACNQ-SGACTWCHGA--CLSGDQAHRLGCGGSPC------SPMPRSPEECR 1859 Query: 989 GYCTCSHCLE------QPG--------CGWCTDPSNTGKGKCI 1017 TCS CL QPG C WCT N +G CI Sbjct: 1860 RLRTCSECLARHPRTLQPGDGEASTPRCKWCT---NCPEGACI 1899 Score = 31.6 bits (70), Expect = 5.7 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 8/89 (8%) Query: 1054 NWSF---IHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCK 1110 +W F + C G C C + C C G+ G C P Sbjct: 1328 SWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCR-CPQGWAGPHCRMALC-PEN 1385 Query: 1111 CNGH--ASLCNTNTGKCFCTTKGVKGDEC 1137 CN H A CN + G C C +G G +C Sbjct: 1386 CNAHTGAGTCNQSLGVCIC-AEGFGGPDC 1413 Score = 31.2 bits (69), Expect = 7.5 Identities = 14/51 (27%), Positives = 19/51 (37%) Query: 79 CEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQC 129 C+ A G +EC C + G C G C C G++G C Sbjct: 152 CQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRAC 202 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 79.0 bits (193), Expect = 3e-14 Identities = 40/103 (38%), Positives = 53/103 (51%), Gaps = 14/103 (13%) Query: 1060 CPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKC----- 1111 C C+C+GH+ +C +C C + TTG HCE C+ GFYG+P+ G G CQPC C Sbjct: 739 CQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIA 798 Query: 1112 -NGHASLCNTNTGK---CFCTTKGVKGDECQLCEVENRYQGNP 1150 N + C+ N G C G G C+ C + Y GNP Sbjct: 799 SNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERC--ADGYYGNP 839 Score = 67.4 bits (163), Expect = 9e-11 Identities = 52/184 (28%), Positives = 69/184 (37%), Gaps = 38/184 (20%) Query: 987 CSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSS- 1045 C+ T HC EQ G+ +PS G C P P + NF P LN Sbjct: 760 CAHNTTGVHC-EQCLPGFYGEPSRGTPGDC------QPCACPLTIASNNFSPTCHLNDGD 812 Query: 1046 --MC--------------LEDSRYNWSFI---HCPACQCNGHSKCINQSICE-------K 1079 +C D Y + C C C+G+ C+ K Sbjct: 813 EVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLK 872 Query: 1080 CENLTTGKHCETCISGFYGDPTNGGKCQPCKCN---GHASLCNTNTGKCFCTTKGVKGDE 1136 C T G HCE C GFYGD C+ C+C+ H+++C+ TG C C V G + Sbjct: 873 CLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDC-KPNVTGQQ 931 Query: 1137 CQLC 1140 C C Sbjct: 932 CDQC 935 Score = 65.1 bits (157), Expect = 5e-10 Identities = 30/68 (44%), Positives = 40/68 (58%), Gaps = 6/68 (8%) Query: 1077 CEKCENLTTGKHCETCISGFYGDP-TNGGKCQPCKCNGHASL---CNTNTGKCFCT--TK 1130 C+ C GKHCE C S +YG+P T GG CQ C CN H S+ C+ +G+C C Sbjct: 1476 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGAS 1535 Query: 1131 GVKGDECQ 1138 G++ DEC+ Sbjct: 1536 GLRCDECE 1543 Score = 61.6 bits (148), Expect = 5e-09 Identities = 59/239 (24%), Positives = 84/239 (35%), Gaps = 30/239 (12%) Query: 922 ANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMST 981 +N+ + C C C G S WC ++C D + P C+ Sbjct: 799 SNNFSPTCHLNDGDEVVCDWCAPGYSGA-WC---ERCADGYYGNPTVPGESCVPCDCSGN 854 Query: 982 CPPENCSGYCT-----CSHCL--------EQPGCGWCTDPSNTGKGKCIEGSYKGPVKMP 1028 P +G+C C CL E+ G+ D + E KG Sbjct: 855 VDPSE-AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAV 913 Query: 1029 SQAPTGNFYPQPLLNSSMCLE--DSRYNWSFIH-CPACQCNGHSK----CINQSICEKCE 1081 TG +P + C + Y H C C C+ C ++ C C Sbjct: 914 CHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCH-CV 972 Query: 1082 NLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCT--TKGVKGDECQ 1138 GK C+ C GFY G C PC C + C+ TG+C C T+GVK +EC+ Sbjct: 973 PGVAGKRCDRCAHGFYA--YQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECE 1029 Score = 61.2 bits (147), Expect = 7e-09 Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 6/80 (7%) Query: 1077 CEKCENLTTGKHCETCISGFY--GDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKG 1134 CE C TG CE+C+SG+Y GG CQPC+C+GHA+ CN + G C G Sbjct: 709 CE-CPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTG 766 Query: 1135 DECQLCEVENRYQGNPLRGT 1154 C+ C + G P RGT Sbjct: 767 VHCEQC--LPGFYGEPSRGT 784 Score = 57.0 bits (136), Expect = 1e-07 Identities = 43/146 (29%), Positives = 60/146 (41%), Gaps = 33/146 (22%) Query: 1016 CIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCI--N 1073 C G ++G K+P+ + G P+PL+ C C CN HS N Sbjct: 1376 CAPGYHRG--KLPAGSDRG---PRPLVAP---------------CVPCSCNNHSDTCDPN 1415 Query: 1074 QSICEKCENLTTGKHCETCISGFYGDPT-NGGKCQPCKC--NGHASLCNT------NTGK 1124 C C + T G HC+ C SG+YG T + C C C + AS T + + Sbjct: 1416 TGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFR 1475 Query: 1125 CFCTTKGVKGDECQLCEVENRYQGNP 1150 C G +G C+ C + Y GNP Sbjct: 1476 CDACLLGYEGKHCERC--SSSYYGNP 1499 Score = 53.1 bits (126), Expect = 2e-06 Identities = 68/284 (23%), Positives = 99/284 (34%), Gaps = 65/284 (22%) Query: 886 EPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANH------SAKQCRTPCALRTAC 939 +PS+AG C ++ + C+ +G+ CER A+ +AK CR AC Sbjct: 856 DPSEAGHCDSVTGECLK------CLGNTDGAHCERCADGFYGDAVTAKNCR-------AC 902 Query: 940 GDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWY----TMSTCPPENCSGYCTCSH 995 +C S C D V QC+ Y + C P NCS + S Sbjct: 903 -ECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSD 961 Query: 996 CLEQPGCGWCTDPSNTGK--GKCIEG--SYKGPVKMPSQAP---------TGNFYPQPLL 1042 G C P GK +C G +Y+ P P TG P Sbjct: 962 GCTDEGQCHCV-PGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHT 1020 Query: 1043 NSSMCLEDSRYNWSF---IHCPACQCN----GHSKCINQSICEKCENLTTGKHCETCISG 1095 C E +W + + C AC C+ H +C + +C++ G+ C+ C G Sbjct: 1021 QGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG 1080 Query: 1096 FYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQL 1139 + P C PC C+ +G GD C L Sbjct: 1081 YRDFPD----CVPCDCD----------------LRGTSGDACNL 1104 Score = 52.4 bits (124), Expect = 3e-06 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 10/71 (14%) Query: 1080 CENLTTGKHCETCISGFYGDPTNGGK----------CQPCKCNGHASLCNTNTGKCFCTT 1129 C T G C+ C G++ G C PC CN H+ C+ NTGKC Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCG 1423 Query: 1130 KGVKGDECQLC 1140 GD C +C Sbjct: 1424 DNTAGDHCDVC 1434 Score = 48.9 bits (115), Expect = 3e-05 Identities = 54/253 (21%), Positives = 84/253 (33%), Gaps = 31/253 (12%) Query: 889 DAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSE 948 + G C +P+ G + C++ G + H + C A + G G Sbjct: 917 ETGLCDC--KPNVTGQQCDQCLHGYYGL----DSGHGCRPCNCSVAGSVSDGCTDEGQCH 970 Query: 949 CMWCSNMKQCVDSNAYVASFPFGQCMEW---YTMSTCPPENCSGYCTCSHCLEQPGCGWC 1005 C+ K+C ++ G C +T +TC PE +G C C + C C Sbjct: 971 CVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPE--TGECVCPPHTQGVKCEEC 1028 Query: 1006 TD-----PSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHC 1060 D + G C S G TG+ + C + S F C Sbjct: 1029 EDGHWGYDAEVGCQAC-NCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC 1087 Query: 1061 PACQCN-------------GHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKC 1106 C C+ G C+ ++ C+ G C C G + N C Sbjct: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGC 1147 Query: 1107 QPCKCNGHASLCN 1119 PC C+G + LC+ Sbjct: 1148 SPCFCSGLSHLCS 1160 Score = 48.1 bits (113), Expect = 6e-05 Identities = 50/197 (25%), Positives = 74/197 (37%), Gaps = 46/197 (23%) Query: 971 GQCMEWYTMSTCPPENCSG--YCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMP 1028 G C+ + S+CP + + C C H C + N +C G ++ P + P Sbjct: 268 GMCICYGHASSCPWDETTKKLQCQCEH-------NTCGESCN----RCCPGYHQQPWR-P 315 Query: 1029 SQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCP-----ACQCNGHSKCINQSICEKCENL 1083 +GN N +D Y+ S A Q G CIN C Sbjct: 316 GTVSSGNTCEA--CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN------CLQN 367 Query: 1084 TTGKHCETCISGFYG----DPTNGGKCQPCKCNGHASLCNT--------------NTGKC 1125 T G +CETCI G+Y P C+PC C+ SL + G+C Sbjct: 368 TMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC 427 Query: 1126 FCTTKGVKGDECQLCEV 1142 C +G G++C C++ Sbjct: 428 PC-KEGYTGEKCDRCQL 443 Score = 37.0 bits (84), Expect = 0.14 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 18/133 (13%) Query: 998 EQPGCGWCT-DPSNTGKGKCIEGSYKGPV---KMPSQAPTGNFYPQPLLNSSMCLEDSRY 1053 E C C DP + CI+ + K P Q P Y C Sbjct: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY-----TGEKCDRCQLG 444 Query: 1054 NWSFIHCPACQCN-----GHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKCQ 1107 + C +C CN C +C+ EN+ GK C+ C GFY N C Sbjct: 445 YKDYPTCVSCGCNPVGSASDEPCTGPCVCK--ENVE-GKACDRCKPGFYNLKEKNPRGCS 501 Query: 1108 PCKCNGHASLCNT 1120 C C G + +C++ Sbjct: 502 ECFCFGVSDVCSS 514 Score = 34.7 bits (78), Expect = 0.68 Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 CD P C+P TG+CVCP G +C+ C Sbjct: 998 CDCPHTQN-TCDPETGECVCPPHTQGVKCEEC 1028 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 77.4 bits (189), Expect = 9e-14 Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 57/208 (27%) Query: 982 CPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVK------- 1026 C P C G+ C +C + G +C KC+ G Y P K Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCD--------KCLPGFYGEPTKGTSEDCQ 805 Query: 1027 ---MPSQAPTGNFYPQPLLNSSMCL-----------------EDSRYNWSFI---HCPAC 1063 P P+ NF P L+ S+ L + + + C C Sbjct: 806 PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC 865 Query: 1064 QCNGH------SKCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS 1116 QCN + C + S C C+ TTG++CE C G++GD + CQPC+CN S Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS 925 Query: 1117 ---LCNTNTGKCFCTTKGVKGDECQLCE 1141 +C++ TG+C C V+G C C+ Sbjct: 926 FSEVCHSQTGQCECRA-NVQGQRCDKCK 952 Score = 61.6 bits (148), Expect = 5e-09 Identities = 49/176 (27%), Positives = 73/176 (41%), Gaps = 39/176 (22%) Query: 978 TMSTCPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029 T+ TC P C+G+ + C +C +C +C G Y +P+ Sbjct: 1413 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE--------RCALGYYGIVKGLPN 1464 Query: 1030 QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089 PL++SS N+S P+C G ++ C C G++C Sbjct: 1465 DCQQ---CACPLISSSN-------NFS----PSCVAEG----LDDYRCTACPRGYEGQYC 1506 Query: 1090 ETCISGFYGDPTN-GGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLCE 1141 E C G+ G P N GG CQ C+C+ + SL C+ TG C C G G +C C+ Sbjct: 1507 ERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC-RPGATGRKCDGCK 1561 Score = 58.9 bits (141), Expect = 3e-08 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 14/103 (13%) Query: 1060 CPACQCNGHSKCINQ--SICEKCENLTTGKHCETCISGFYGDPTN-GGKCQPCKC----- 1111 C CQCNGHS + SIC+ C++ T G CE C G+YG CQ C C Sbjct: 1417 CVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISS 1476 Query: 1112 -NGHASLC---NTNTGKCFCTTKGVKGDECQLCEVENRYQGNP 1150 N + C + +C +G +G C+ C Y G+P Sbjct: 1477 SNNFSPSCVAEGLDDYRCTACPRGYEGQYCERC--APGYTGSP 1517 Score = 55.5 bits (132), Expect = 4e-07 Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 1076 ICEKCENLT--TGKHCETCISGFY------GDPTNG---GKCQPCKCNGHASLCNTNTGK 1124 + EKC+ +G CE C+ GFY G T G G C PC+CNGH+SLC+ T Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI 1435 Query: 1125 CFCTTKGVKGDECQLC 1140 C GD C+ C Sbjct: 1436 CQNCQHHTAGDFCERC 1451 Score = 52.0 bits (123), Expect = 4e-06 Identities = 67/281 (23%), Positives = 95/281 (33%), Gaps = 47/281 (16%) Query: 918 CERPANHSAKQCRTPCA----LRTACG----DCTSGSSECMWCSNMKQCVDSNAYVASFP 969 CE AN ++C A L++A G +C S S+ C QC V Sbjct: 937 CECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPG-VTGKK 995 Query: 970 FGQCMEWYTMSTCPPENCSGYCTCSHCLEQ--PGCGWCTDPSNTGKGKCIEG-------- 1019 +C Y C+ C CSH P G C P NT KC + Sbjct: 996 CDRCAHGYF--NFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052 Query: 1020 ----------SYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC---- 1065 S G + TG P + + C E SR +W++ C C C Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG 1112 Query: 1066 ---------NGHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHA 1115 C +Q+ C+ G HC+ C G +G D N C C C G Sbjct: 1113 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT 1172 Query: 1116 SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCY 1156 + C+ G T +K ++ L V+ Q +G + Sbjct: 1173 TQCSEAKG-LIRTWVTLKAEQTILPLVDEALQHTTTKGIVF 1212 Score = 47.8 bits (112), Expect = 8e-05 Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 31/108 (28%) Query: 1063 CQCNGHSKCI------NQSICEKCENLTTGKHCETCISGFYGDPTNGG------KCQPCK 1110 C C GH++ N+S CE CE+ T G C+ C GF+ P G +C+ C Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345 Query: 1111 CNGHASLCNTNT------------------GKCFCTTKGVKGDECQLC 1140 C+G A C + G C T+ G C+ C Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393 Score = 47.4 bits (111), Expect = 1e-04 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 5/81 (6%) Query: 1076 ICEKCENLTTGKHCETCISGF--YGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVK 1133 +C+ C TG CE+C GG C+PC+C GHA C+ TG+C Sbjct: 723 VCQ-CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTG 781 Query: 1134 GDECQLCEVENRYQGNPLRGT 1154 G C C + G P +GT Sbjct: 782 GPYCDKC--LPGFYGEPTKGT 800 Score = 47.0 bits (110), Expect = 1e-04 Identities = 37/127 (29%), Positives = 43/127 (33%), Gaps = 39/127 (30%) Query: 1060 CPACQCNGHS--------------------KCINQSICEKCENLTTGKHCETCISGFYG- 1098 C AC C+G + K I +C C T G +CETC GF+ Sbjct: 341 CEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400 Query: 1099 ---DPTNGGKCQPCKCNGHASL---C---------NTNTGKCFCTTKGVKGDECQLCEVE 1143 P CQPC C+ SL C G C C T G G C C Sbjct: 401 KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT-GFGGVSCDRC--A 457 Query: 1144 NRYQGNP 1150 Y G P Sbjct: 458 RGYTGYP 464 Score = 40.4 bits (93), Expect = 0.012 Identities = 63/267 (23%), Positives = 88/267 (32%), Gaps = 74/267 (27%) Query: 95 AAEAKECDRPCVNGGRCNPG----------TGQCVCPAGWVGEQCQHC-GGRFRLTGSSG 143 A +AK C +PC RCN G TGQC C A G++C C G F L + G Sbjct: 909 AVDAKNC-QPC----RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARG 963 Query: 144 FVTDGPGNYKYKT-------KCTWLIEG-QPNRIMRLRFNHF------ATECSWDHLYVY 189 V ++ K+ +C W G + R +F T C HL Sbjct: 964 CVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL--- 1019 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEV--VATSGYALLHFFSDAAYNLTGFNITYSF 247 GN P+ + S A N G +IT Sbjct: 1020 ----------------------GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGC 1057 Query: 248 DMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCT-DNCGFPHRGICN------ 300 C NCS G + +T +C C + G C C+ + +P +C+ Sbjct: 1058 KAC--NCSTVGSLDFQCNVNTGQCNCHPKFSGAKC--TECSRGHWNYPRCNLCDCFLPGT 1113 Query: 301 -----SSDVRGCSCFSDWQGPGCSVPV 322 S+ + CSC C V V Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNV 1140 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 77.4 bits (189), Expect = 9e-14 Identities = 56/208 (26%), Positives = 82/208 (39%), Gaps = 57/208 (27%) Query: 982 CPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVK------- 1026 C P C G+ C +C + G +C KC+ G Y P K Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCD--------KCLPGFYGEPTKGTSEDCQ 805 Query: 1027 ---MPSQAPTGNFYPQPLLNSSMCL-----------------EDSRYNWSFI---HCPAC 1063 P P+ NF P L+ S+ L + + + C C Sbjct: 806 PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC 865 Query: 1064 QCNGH------SKCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS 1116 QCN + C + S C C+ TTG++CE C G++GD + CQPC+CN S Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS 925 Query: 1117 ---LCNTNTGKCFCTTKGVKGDECQLCE 1141 +C++ TG+C C V+G C C+ Sbjct: 926 FSEVCHSQTGQCECRA-NVQGQRCDKCK 952 Score = 61.6 bits (148), Expect = 5e-09 Identities = 49/176 (27%), Positives = 73/176 (41%), Gaps = 39/176 (22%) Query: 978 TMSTCPPENCSGYCT--------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029 T+ TC P C+G+ + C +C +C +C G Y +P+ Sbjct: 1413 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE--------RCALGYYGIVKGLPN 1464 Query: 1030 QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089 PL++SS N+S P+C G ++ C C G++C Sbjct: 1465 DCQQ---CACPLISSSN-------NFS----PSCVAEG----LDDYRCTACPRGYEGQYC 1506 Query: 1090 ETCISGFYGDPTN-GGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLCE 1141 E C G+ G P N GG CQ C+C+ + SL C+ TG C C G G +C C+ Sbjct: 1507 ERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC-RPGATGRKCDGCK 1561 Score = 58.9 bits (141), Expect = 3e-08 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 14/103 (13%) Query: 1060 CPACQCNGHSKCINQ--SICEKCENLTTGKHCETCISGFYGDPTN-GGKCQPCKC----- 1111 C CQCNGHS + SIC+ C++ T G CE C G+YG CQ C C Sbjct: 1417 CVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISS 1476 Query: 1112 -NGHASLC---NTNTGKCFCTTKGVKGDECQLCEVENRYQGNP 1150 N + C + +C +G +G C+ C Y G+P Sbjct: 1477 SNNFSPSCVAEGLDDYRCTACPRGYEGQYCERC--APGYTGSP 1517 Score = 55.5 bits (132), Expect = 4e-07 Identities = 30/76 (39%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 1076 ICEKCENLT--TGKHCETCISGFY------GDPTNG---GKCQPCKCNGHASLCNTNTGK 1124 + EKC+ +G CE C+ GFY G T G G C PC+CNGH+SLC+ T Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI 1435 Query: 1125 CFCTTKGVKGDECQLC 1140 C GD C+ C Sbjct: 1436 CQNCQHHTAGDFCERC 1451 Score = 52.0 bits (123), Expect = 4e-06 Identities = 67/281 (23%), Positives = 95/281 (33%), Gaps = 47/281 (16%) Query: 918 CERPANHSAKQCRTPCA----LRTACG----DCTSGSSECMWCSNMKQCVDSNAYVASFP 969 CE AN ++C A L++A G +C S S+ C QC V Sbjct: 937 CECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPG-VTGKK 995 Query: 970 FGQCMEWYTMSTCPPENCSGYCTCSHCLEQ--PGCGWCTDPSNTGKGKCIEG-------- 1019 +C Y C+ C CSH P G C P NT KC + Sbjct: 996 CDRCAHGYF--NFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052 Query: 1020 ----------SYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC---- 1065 S G + TG P + + C E SR +W++ C C C Sbjct: 1053 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG 1112 Query: 1066 ---------NGHSKCINQSICEKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHA 1115 C +Q+ C+ G HC+ C G +G D N C C C G Sbjct: 1113 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT 1172 Query: 1116 SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCY 1156 + C+ G T +K ++ L V+ Q +G + Sbjct: 1173 TQCSEAKG-LIRTWVTLKAEQTILPLVDEALQHTTTKGIVF 1212 Score = 47.8 bits (112), Expect = 8e-05 Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 31/108 (28%) Query: 1063 CQCNGHSKCI------NQSICEKCENLTTGKHCETCISGFYGDPTNGG------KCQPCK 1110 C C GH++ N+S CE CE+ T G C+ C GF+ P G +C+ C Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345 Query: 1111 CNGHASLCNTNT------------------GKCFCTTKGVKGDECQLC 1140 C+G A C + G C T+ G C+ C Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393 Score = 47.4 bits (111), Expect = 1e-04 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 5/81 (6%) Query: 1076 ICEKCENLTTGKHCETCISGF--YGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVK 1133 +C+ C TG CE+C GG C+PC+C GHA C+ TG+C Sbjct: 723 VCQ-CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTG 781 Query: 1134 GDECQLCEVENRYQGNPLRGT 1154 G C C + G P +GT Sbjct: 782 GPYCDKC--LPGFYGEPTKGT 800 Score = 47.0 bits (110), Expect = 1e-04 Identities = 37/127 (29%), Positives = 43/127 (33%), Gaps = 39/127 (30%) Query: 1060 CPACQCNGHS--------------------KCINQSICEKCENLTTGKHCETCISGFYG- 1098 C AC C+G + K I +C C T G +CETC GF+ Sbjct: 341 CEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400 Query: 1099 ---DPTNGGKCQPCKCNGHASL---C---------NTNTGKCFCTTKGVKGDECQLCEVE 1143 P CQPC C+ SL C G C C T G G C C Sbjct: 401 KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT-GFGGVSCDRC--A 457 Query: 1144 NRYQGNP 1150 Y G P Sbjct: 458 RGYTGYP 464 Score = 40.4 bits (93), Expect = 0.012 Identities = 63/267 (23%), Positives = 88/267 (32%), Gaps = 74/267 (27%) Query: 95 AAEAKECDRPCVNGGRCNPG----------TGQCVCPAGWVGEQCQHC-GGRFRLTGSSG 143 A +AK C +PC RCN G TGQC C A G++C C G F L + G Sbjct: 909 AVDAKNC-QPC----RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARG 963 Query: 144 FVTDGPGNYKYKT-------KCTWLIEG-QPNRIMRLRFNHF------ATECSWDHLYVY 189 V ++ K+ +C W G + R +F T C HL Sbjct: 964 CVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL--- 1019 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEV--VATSGYALLHFFSDAAYNLTGFNITYSF 247 GN P+ + S A N G +IT Sbjct: 1020 ----------------------GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGC 1057 Query: 248 DMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCT-DNCGFPHRGICN------ 300 C NCS G + +T +C C + G C C+ + +P +C+ Sbjct: 1058 KAC--NCSTVGSLDFQCNVNTGQCNCHPKFSGAKC--TECSRGHWNYPRCNLCDCFLPGT 1113 Query: 301 -----SSDVRGCSCFSDWQGPGCSVPV 322 S+ + CSC C V V Sbjct: 1114 DATTCDSETKKCSCSDQTGQCTCKVNV 1140 >gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo sapiens] Length = 986 Score = 75.1 bits (183), Expect = 5e-13 Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 22/156 (14%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWV----GEQCQHCGGRFRLTGSSGFVT--DGPGNYKY 154 C + CVN G+ +C C +G+V C+ G ++T +SG +T + P Y Sbjct: 714 CQQDCVN----TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPS 769 Query: 155 KTKCTWLIEGQPNRIMRLRFNHF----ATECSWDHLYVYDGDSIYAPLVAAFSGLIVPER 210 K +CTW I P ++L F EC++DHL V+DG AP++ F G PE Sbjct: 770 KKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPE- 828 Query: 211 DGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS 246 V+AT L F+SD + GF +++ Sbjct: 829 -------PVLATGSRMFLRFYSDNSVQRKGFQASHA 857 Score = 53.9 bits (128), Expect = 1e-06 Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 15/167 (8%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLY 187 CGG + + P +Y+ C W I+ + L F F E C++D+L Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY-- 245 V DG S + L+ + G P+ ++ +TS L F SD + N GF + + Sbjct: 495 VRDGHSESSTLIGRYCGYEKPD--------DIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546 Query: 246 SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292 D C G E + N+ + +C C ++ A D C CG Sbjct: 547 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYE-LAPDKRRCEAACG 592 Score = 46.6 bits (109), Expect = 2e-04 Identities = 55/198 (27%), Positives = 78/198 (39%), Gaps = 36/198 (18%) Query: 97 EAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTGSSGFVT 146 E EC RP N G C G+ +C C G+ +C+ G F LT +G +T Sbjct: 547 EVDECSRP--NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGF-LTKLNGSIT 603 Query: 147 DG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVA 200 P Y C W + + L+F+ F TE C +D + V G + + L Sbjct: 604 SPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHG 663 Query: 201 AFSGLIVPERDGNETVPEVVATSGY--ALLHFFSDAAYNLTGFNITYSFDMCPNNCS-GR 257 F G PE V TS Y + F SD + GF + D + CS Sbjct: 664 KFCGSEKPE----------VITSQYNNMRVEFKSDNTVSKKGFKAHFFSD--KDECSKDN 711 Query: 258 GECK--ISNSSDTVECEC 273 G C+ N+ + EC+C Sbjct: 712 GGCQQDCVNTFGSYECQC 729 Score = 46.2 bits (108), Expect = 2e-04 Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 16/132 (12%) Query: 123 GWVGEQCQHCGGRFRLTGSS----GFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFA 178 G+ CGG+ R + G NY C W+I + + L F F Sbjct: 851 GFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE 910 Query: 179 ----TECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDA 234 T+C +D++ ++DG AP + + G PE EV + L+ F SD Sbjct: 911 VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPE--------EVYSAGDSVLVKFHSDD 962 Query: 235 AYNLTGFNITYS 246 GF++ Y+ Sbjct: 963 TITKKGFHLRYT 974 Score = 35.0 bits (79), Expect = 0.52 Identities = 30/122 (24%), Positives = 46/122 (37%), Gaps = 12/122 (9%) Query: 128 QCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHF----ATECSW 183 +C CG + + + + P Y C W I P + L F + C + Sbjct: 318 KCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWY 377 Query: 184 DHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI 243 D++ V DG APL F G +PE +V+T + F S + + GF Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPE--------PIVSTDSRLWVEFRSSSNWVGKGFFA 429 Query: 244 TY 245 Y Sbjct: 430 VY 431 >gi|119703755 laminin, beta 2 precursor [Homo sapiens] Length = 1798 Score = 74.3 bits (181), Expect = 8e-13 Identities = 66/247 (26%), Positives = 97/247 (39%), Gaps = 32/247 (12%) Query: 914 NGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQC 973 + + ER A QC G S +S C+ + + + Y + P QC Sbjct: 734 DAAALERQATFERYQCHEE-------GLVPSKTSPSEACAPLLISLSTLIYNGALPC-QC 785 Query: 974 MEWYTMST-CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMP 1028 ++S+ C P G C C + C C P G G + + S++G + Sbjct: 786 NPQGSLSSECNPHG--GQCLCKPGVVGRRCDLCA-PGYYGFGPTGCQACQCSHEGALSSL 842 Query: 1029 SQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQ--SICEKCENLTTG 1086 + +G + C R W F C C CNGH+ N C C + T G Sbjct: 843 CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGG 902 Query: 1087 KHCETCISGFYGDP--TNGGKCQPCKC-------NGHASLCNTNTGK----CFCTTKGVK 1133 +HCE CI+GF+GDP GG+C+PC C A+ C+ + C C G Sbjct: 903 EHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA-GYT 961 Query: 1134 GDECQLC 1140 G C+ C Sbjct: 962 GLRCEAC 968 Score = 60.8 bits (146), Expect = 9e-09 Identities = 68/246 (27%), Positives = 95/246 (38%), Gaps = 44/246 (17%) Query: 921 PANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMS 980 P A QC AL + C + TSG C + +C FP Sbjct: 825 PTGCQACQCSHEGALSSLC-EKTSGQCLCRTGAFGLRCDRCQRGQWGFP----------- 872 Query: 981 TCPPENCSGYCTCSHCLEQPG-CGWCTDPSNTGKG---KCIEGSYKGPVKMPSQAPTGNF 1036 +C P C+G+ C G C C D +TG +CI G + G ++P G Sbjct: 873 SCRPCVCNGHA--DECNTHTGACLGCRD--HTGGEHCERCIAG-FHGDPRLPYG---GQC 924 Query: 1037 YPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGF 1096 P P C E F A C H +Q I C TG CE C G Sbjct: 925 RPCP------CPEGPGSQRHF----ATSC--HQDEYSQQIVCHCRAGYTGLRCEACAPGH 972 Query: 1097 YGDPTN-GGKCQPCKCNGH-----ASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNP 1150 +GDP+ GG+CQ C+C+G+ C+ +TG+C +G C C + + G Sbjct: 973 FGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHC--KPGFHGQA 1030 Query: 1151 LRGTCY 1156 R +C+ Sbjct: 1031 ARQSCH 1036 Score = 53.1 bits (126), Expect = 2e-06 Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 30/110 (27%) Query: 1060 CPACQCNGHSKC-------------INQSICEKCENLTTGKHCETCISGFYGDPT----N 1102 C C+C+GH+ ++ +C+ C++ T G+HCE C FY DPT + Sbjct: 344 CRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRD 403 Query: 1103 GGKCQPCKCNGHAS----LCNTN--------TGKCFCTTKGVKGDECQLC 1140 C+ C C+ S C+++ +G+C C + V G CQ C Sbjct: 404 PAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRC-KEHVVGTRCQQC 452 Score = 44.3 bits (103), Expect = 9e-04 Identities = 62/270 (22%), Positives = 92/270 (34%), Gaps = 71/270 (26%) Query: 929 CRTPCALRTACGDCTSGSSECMWC------SNMKQCVDSNAYVASFPFG-QCM------- 974 CR PC +C + + C+ C + ++C+ P+G QC Sbjct: 874 CR-PCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEG 932 Query: 975 ---EWYTMSTCPPENCSGYCTCSHC------LEQPGC--GWCTDPSNTGKGKCIEGSYKG 1023 + + ++C + S C HC L C G DPS G G+C G Sbjct: 933 PGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDPSRPG-GRCQLCECSG 990 Query: 1024 PVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCE-N 1082 + P P ++ CL ++ HC C+ H + QS C +C N Sbjct: 991 NID-----PMDPDACDP--HTGQCLR-CLHHTEGPHCAHCKPGFHGQAARQS-CHRCTCN 1041 Query: 1083 L----------------------------TTGKHCETCISGFYGDPTNGGKCQPCKCN-- 1112 L G C+ C F+ + T+G CQPC C+ Sbjct: 1042 LLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW-NLTSGHGCQPCACHPS 1100 Query: 1113 -GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141 CN TG+C C G G C C+ Sbjct: 1101 RARGPTCNEFTGQCHCRA-GFGGRTCSECQ 1129 Score = 42.4 bits (98), Expect = 0.003 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 7/68 (10%) Query: 1079 KCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASL-----CNTNTGKCFCTTKGV 1132 +C+ G C+ C GF+G ++ C+ C+CN ++ C+ N+G C+C + V Sbjct: 439 RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYC-KRLV 497 Query: 1133 KGDECQLC 1140 G C C Sbjct: 498 TGRGCDRC 505 Score = 37.7 bits (86), Expect = 0.080 Identities = 38/149 (25%), Positives = 53/149 (35%), Gaps = 29/149 (19%) Query: 982 CP-PENC-----SGYCTCSHCLEQPGCGWCTD---PSNTGKG----KCIEGSYKGPVKMP 1028 CP P+ C SG C C ++ P C C +G G C +GP Sbjct: 1050 CPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPT--- 1106 Query: 1029 SQAPTGNFYPQPLLNSSMCLEDSRYNWS--FIHCPACQCNGHSKCINQSICEK------C 1080 TG + + C E +W + C AC C+ S+ I+ C + C Sbjct: 1107 CNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD--SRGIDTPQCHRFTGHCSC 1164 Query: 1081 ENLTTGKHCETCISGFYGDPTNGGKCQPC 1109 +G C+ C GF G C PC Sbjct: 1165 RPGVSGVRCDQCARGFSG---IFPACHPC 1190 Score = 35.0 bits (79), Expect = 0.52 Identities = 15/44 (34%), Positives = 21/44 (47%) Query: 100 ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSG 143 +C+ CNP GQC+C G VG +C C + G +G Sbjct: 784 QCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG 827 Score = 33.9 bits (76), Expect = 1.2 Identities = 14/32 (43%), Positives = 15/32 (46%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 C G CN TGQC C AG+ G C C Sbjct: 1097 CHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128 Score = 31.2 bits (69), Expect = 7.5 Identities = 12/41 (29%), Positives = 17/41 (41%) Query: 92 GSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 G +A +C C +GQC+C G G +C C Sbjct: 824 GPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRC 864 Score = 30.8 bits (68), Expect = 9.8 Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 98 AKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRF 136 A +CD ++ +C+ TG C C G G +C C F Sbjct: 1142 ACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180 >gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] Length = 3333 Score = 73.2 bits (178), Expect = 2e-12 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%) Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114 C C CNGHS +C + S IC C++ T G+HCE C G+YG+ + G C+ C C N Sbjct: 1684 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 1742 Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155 A+ C N G C+ K G G +C+ C Y GNP + G+C Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 1784 Score = 61.6 bits (148), Expect = 5e-09 Identities = 50/181 (27%), Positives = 72/181 (39%), Gaps = 32/181 (17%) Query: 982 CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG--KCIEGSYKGPVKMPS-------QAP 1032 C P +G HC + G C P+ G+ +C G Y P P + Sbjct: 1268 CHPTGATG----PHCSPEGGQCPC-QPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEM 1322 Query: 1033 TGNFYPQPLLNSSMCLEDSRYNWSF---IHCPACQCNGHS-------KCINQSICEKCEN 1082 TG P C +++SF C C C+ +C S +C+ Sbjct: 1323 TGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382 Query: 1083 LTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKGVKGDECQL 1139 TG+ C+ C SGFY P +C PC CN + +C+ TG C C + V+G EC + Sbjct: 1383 RITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGACLC-KENVEGTECNV 1437 Query: 1140 C 1140 C Sbjct: 1438 C 1438 Score = 60.1 bits (144), Expect = 2e-08 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 4/78 (5%) Query: 1080 CENLTTGKHCETCISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDEC 1137 C G C+ C G+Y D G+C PC CNGH++ C +G C G+ C Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHC 1715 Query: 1138 QLCEVENRYQGNPLRGTC 1155 + C + Y GN + G+C Sbjct: 1716 ERC--QEGYYGNAVHGSC 1731 Score = 59.7 bits (143), Expect = 2e-08 Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 14/125 (11%) Query: 1035 NFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICE------KCENLTTGKH 1088 +FY P S C +R +F H A C H C C+ G+ Sbjct: 1236 SFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQ 1295 Query: 1089 CETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQG 1148 C C +G YG P +C+PC C LC TG+C C + V+ +C++CE + + Sbjct: 1296 CTRCATGHYGFP----RCKPCSCG--RRLCEEMTGQCRCPPRTVR-PQCEVCETHS-FSF 1347 Query: 1149 NPLRG 1153 +P+ G Sbjct: 1348 HPMAG 1352 Score = 58.2 bits (139), Expect = 6e-08 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%) Query: 982 CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037 C P NC+G+ + C Q G G C + + G +C EG Y V +A Sbjct: 1684 CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 1734 Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096 P P NS C NG +C C+ TG CE C G+ Sbjct: 1735 PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 1773 Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140 +G+P GG CQPC CN + L C+ TG C ++ + D+C C Sbjct: 1774 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825 Score = 57.8 bits (138), Expect = 7e-08 Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 27/114 (23%) Query: 1055 WSFIH-CPACQCNGH-SKCINQ-------------------SICEKCENLTTGKHCETCI 1093 W H C AC C+GH S C +C C++ T G +CE C Sbjct: 347 WEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCA 406 Query: 1094 SGF---YGDPTNG-GKCQPCKCN-GHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142 G+ YG P + C PC C+ HA C +G+C C GD C+ C + Sbjct: 407 KGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHC-KPNFHGDNCEKCAI 459 Score = 50.8 bits (120), Expect = 9e-06 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 15/79 (18%) Query: 1065 CNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTN 1121 C+ H +C+ C G C+TC SGFY P CQ C C+ S C++ Sbjct: 503 CDAHGRCL-------CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQMPCSSV 551 Query: 1122 TGKCFCTTKGVKGDECQLC 1140 TG+C C GV G C C Sbjct: 552 TGQCEC-RPGVTGQRCDRC 569 Score = 45.1 bits (105), Expect = 5e-04 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 8/92 (8%) Query: 1055 WSFIHCPACQCN--GHSKCINQSICEKCENL--TTGKHCETCISGFYGDPTNGGKCQPCK 1110 +SF C AC C+ G + S+ +CE TG+ C+ C+SG Y P G C Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC- 586 Query: 1111 CNGHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142 A N+N G C C V+G C C++ Sbjct: 587 --DPAGTINSNLGYCQCKLH-VEGPTCSRCKL 615 Score = 42.7 bits (99), Expect = 0.002 Identities = 59/266 (22%), Positives = 94/266 (35%), Gaps = 69/266 (25%) Query: 896 LSEPSTRGLKAATCINPLNG-SVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSN 954 L P G + TC + +C+ + + PC+ T +C G + Sbjct: 510 LCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTG----QR 565 Query: 955 MKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS----GYCTCSHCLEQPGCGWCTDPSN 1010 +C+ S AY FP Q + S C P GYC C +E P C C Sbjct: 566 CDRCL-SGAY--DFPHCQG----SSSACDPAGTINSNLGYCQCKLHVEGPTCSRC----- 613 Query: 1011 TGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSK 1070 K + + + + P+G C C+C+ Sbjct: 614 ----KLLYWN------LDKENPSG-------------------------CSECKCHKAGT 638 Query: 1071 CINQSICEK------CENLTTGKHCETCISGFYG-DPTNGGKCQPCKCN---GHASLCNT 1120 C + C++ G C+TC G++ + +N CQ C+C+ +S+C+ Sbjct: 639 VSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698 Query: 1121 NTGKCFCTTKGVKGDECQLCEVENRY 1146 +G C C + V G CQ EN Y Sbjct: 699 PSGVCQC-REHVVGKVCQ--RPENNY 721 Score = 41.6 bits (96), Expect = 0.006 Identities = 65/303 (21%), Positives = 96/303 (31%), Gaps = 95/303 (31%) Query: 909 CINPLNGSVCERPANHSAKQCRTPCALRTA---CGDCTSGSSECMWCSNMKQCVDSNAYV 965 C+ + VC N+ K R C T C C +G ++ W Sbjct: 299 CVCNGHAEVCN--INNPEKLFRCECQHHTCGETCDRCCTGYNQRRW-------------- 342 Query: 966 ASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQP----------------GCGWCTDPS 1009 + W C NC G+ S+C P G G C + Sbjct: 343 ------RPAAWEQSHECEACNCHGHA--SNCYYDPDVERQQASLNTQGIYAGGGVCINCQ 394 Query: 1010 NTGKG----KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC 1065 + G +C +G Y+ P +P AP G C D H C+ Sbjct: 395 HNTAGVNCEQCAKGYYR-PYGVPVDAPDGCI---------PCSCDPE------HADGCE- 437 Query: 1066 NGHSKCINQSICEKCENLTTGKHCETCISGFYGDP-----------------TNGGKCQP 1108 G +C C+ G +CE C G+Y P G + Sbjct: 438 QGSGRC-------HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490 Query: 1109 CKCNGHA---SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQF 1165 C CN +C+ + G+C C GV+G C C + + P+ C+ + L YQ Sbjct: 491 CDCNLEGVLPEICDAH-GRCLC-RPGVEGPRCDTC--RSGFYSFPICQACWCSALGSYQM 546 Query: 1166 TFS 1168 S Sbjct: 547 PCS 549 Score = 40.4 bits (93), Expect = 0.012 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 9/84 (10%) Query: 245 YSFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEAC--------DIPHCTDNCGFPH 295 YSF +C CS G ++ SS T +CEC G+ C D PHC + Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587 Query: 296 RGICNSSDVRGCSCFSDWQGPGCS 319 +S++ C C +GP CS Sbjct: 588 PAGTINSNLGYCQCKLHVEGPTCS 611 Score = 40.4 bits (93), Expect = 0.012 Identities = 50/220 (22%), Positives = 70/220 (31%), Gaps = 46/220 (20%) Query: 915 GSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCM 974 G C N +QC T C G C CS ++ + GQC Sbjct: 1282 GGQCPCQPNVIGRQC-------TRCATGHYGFPRCKPCSCGRRLCEEMT-------GQCR 1327 Query: 975 EWYTMSTCPPENCSGYCTC--SHCLE---QPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029 CPP C +H GC C N + IE + MP Sbjct: 1328 -------CPPRTVRPQCEVCETHSFSFHPMAGCEGC----NCSRRGTIEAA------MPE 1370 Query: 1030 -QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEK------CEN 1082 +G +P + C + + F C C CN +C+ C+ Sbjct: 1371 CDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT--EPGVCDPGTGACLCKE 1428 Query: 1083 LTTGKHCETCISG-FYGDPTNGGKCQPCKCNGHASLCNTN 1121 G C C G F+ DP N C C C G + C+++ Sbjct: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSS 1468 Score = 37.0 bits (84), Expect = 0.14 Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 10/59 (16%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFVTDGPGNYKYKTKC 158 C+R G C+PGTG C+C G +C C G F L P N K T C Sbjct: 1407 CNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL---------DPANLKGCTSC 1456 Score = 35.8 bits (81), Expect = 0.30 Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 5/45 (11%) Query: 100 ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGF 144 EC G C+P GQC C +G QC C TG GF Sbjct: 1267 ECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA-----TGHYGF 1306 Score = 32.0 bits (71), Expect = 4.4 Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 103 RPCVNGGR-CNPGTGQCVCPAGWVGEQCQHC 132 +PC G R C TGQC CP V QC+ C Sbjct: 1310 KPCSCGRRLCEEMTGQCRCPPRTVRPQCEVC 1340 Score = 31.6 bits (70), Expect = 5.7 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%) Query: 254 CSGRGE-CKISNSSDTVECECSENWKGEACD 283 C+G E C I+N CEC + GE CD Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCD 331 Score = 30.8 bits (68), Expect = 9.8 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 89 AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132 AV GS A C P N G N G +C C AG+ G QC+ C Sbjct: 1726 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769 >gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] Length = 1668 Score = 73.2 bits (178), Expect = 2e-12 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%) Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114 C C CNGHS +C + S IC C++ T G+HCE C G+YG+ + G C+ C C N Sbjct: 75 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 133 Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155 A+ C N G C+ K G G +C+ C Y GNP + G+C Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 175 Score = 58.2 bits (139), Expect = 6e-08 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%) Query: 982 CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037 C P NC+G+ + C Q G G C + + G +C EG Y V +A Sbjct: 75 CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 125 Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096 P P NS C NG +C C+ TG CE C G+ Sbjct: 126 PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 164 Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140 +G+P GG CQPC CN + L C+ TG C ++ + D+C C Sbjct: 165 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 216 Score = 53.9 bits (128), Expect = 1e-06 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 4/66 (6%) Query: 1092 CISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGN 1149 C G+Y D G+C PC CNGH++ C +G C G+ C+ C + Y GN Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC--QEGYYGN 116 Query: 1150 PLRGTC 1155 + G+C Sbjct: 117 AVHGSC 122 Score = 30.8 bits (68), Expect = 9.8 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 89 AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132 AV GS A C P N G N G +C C AG+ G QC+ C Sbjct: 117 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 160 >gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] Length = 3277 Score = 73.2 bits (178), Expect = 2e-12 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%) Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114 C C CNGHS +C + S IC C++ T G+HCE C G+YG+ + G C+ C C N Sbjct: 1684 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 1742 Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155 A+ C N G C+ K G G +C+ C Y GNP + G+C Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 1784 Score = 61.6 bits (148), Expect = 5e-09 Identities = 50/181 (27%), Positives = 72/181 (39%), Gaps = 32/181 (17%) Query: 982 CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG--KCIEGSYKGPVKMPS-------QAP 1032 C P +G HC + G C P+ G+ +C G Y P P + Sbjct: 1268 CHPTGATG----PHCSPEGGQCPC-QPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEM 1322 Query: 1033 TGNFYPQPLLNSSMCLEDSRYNWSF---IHCPACQCNGHS-------KCINQSICEKCEN 1082 TG P C +++SF C C C+ +C S +C+ Sbjct: 1323 TGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKP 1382 Query: 1083 LTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKGVKGDECQL 1139 TG+ C+ C SGFY P +C PC CN + +C+ TG C C + V+G EC + Sbjct: 1383 RITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGACLC-KENVEGTECNV 1437 Query: 1140 C 1140 C Sbjct: 1438 C 1438 Score = 60.1 bits (144), Expect = 2e-08 Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 4/78 (5%) Query: 1080 CENLTTGKHCETCISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDEC 1137 C G C+ C G+Y D G+C PC CNGH++ C +G C G+ C Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHC 1715 Query: 1138 QLCEVENRYQGNPLRGTC 1155 + C + Y GN + G+C Sbjct: 1716 ERC--QEGYYGNAVHGSC 1731 Score = 59.7 bits (143), Expect = 2e-08 Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 14/125 (11%) Query: 1035 NFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICE------KCENLTTGKH 1088 +FY P S C +R +F H A C H C C+ G+ Sbjct: 1236 SFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQ 1295 Query: 1089 CETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQG 1148 C C +G YG P +C+PC C LC TG+C C + V+ +C++CE + + Sbjct: 1296 CTRCATGHYGFP----RCKPCSCG--RRLCEEMTGQCRCPPRTVR-PQCEVCETHS-FSF 1347 Query: 1149 NPLRG 1153 +P+ G Sbjct: 1348 HPMAG 1352 Score = 58.2 bits (139), Expect = 6e-08 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%) Query: 982 CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037 C P NC+G+ + C Q G G C + + G +C EG Y V +A Sbjct: 1684 CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 1734 Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096 P P NS C NG +C C+ TG CE C G+ Sbjct: 1735 PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 1773 Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140 +G+P GG CQPC CN + L C+ TG C ++ + D+C C Sbjct: 1774 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 1825 Score = 57.8 bits (138), Expect = 7e-08 Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 27/114 (23%) Query: 1055 WSFIH-CPACQCNGH-SKCINQ-------------------SICEKCENLTTGKHCETCI 1093 W H C AC C+GH S C +C C++ T G +CE C Sbjct: 347 WEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCA 406 Query: 1094 SGF---YGDPTNG-GKCQPCKCN-GHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142 G+ YG P + C PC C+ HA C +G+C C GD C+ C + Sbjct: 407 KGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHC-KPNFHGDNCEKCAI 459 Score = 50.8 bits (120), Expect = 9e-06 Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 15/79 (18%) Query: 1065 CNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTN 1121 C+ H +C+ C G C+TC SGFY P CQ C C+ S C++ Sbjct: 503 CDAHGRCL-------CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQMPCSSV 551 Query: 1122 TGKCFCTTKGVKGDECQLC 1140 TG+C C GV G C C Sbjct: 552 TGQCEC-RPGVTGQRCDRC 569 Score = 45.1 bits (105), Expect = 5e-04 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 8/92 (8%) Query: 1055 WSFIHCPACQCN--GHSKCINQSICEKCENL--TTGKHCETCISGFYGDPTNGGKCQPCK 1110 +SF C AC C+ G + S+ +CE TG+ C+ C+SG Y P G C Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC- 586 Query: 1111 CNGHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142 A N+N G C C V+G C C++ Sbjct: 587 --DPAGTINSNLGYCQCKLH-VEGPTCSRCKL 615 Score = 42.7 bits (99), Expect = 0.002 Identities = 59/266 (22%), Positives = 94/266 (35%), Gaps = 69/266 (25%) Query: 896 LSEPSTRGLKAATCINPLNG-SVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSN 954 L P G + TC + +C+ + + PC+ T +C G + Sbjct: 510 LCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTG----QR 565 Query: 955 MKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS----GYCTCSHCLEQPGCGWCTDPSN 1010 +C+ S AY FP Q + S C P GYC C +E P C C Sbjct: 566 CDRCL-SGAY--DFPHCQG----SSSACDPAGTINSNLGYCQCKLHVEGPTCSRC----- 613 Query: 1011 TGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSK 1070 K + + + + P+G C C+C+ Sbjct: 614 ----KLLYWN------LDKENPSG-------------------------CSECKCHKAGT 638 Query: 1071 CINQSICEK------CENLTTGKHCETCISGFYG-DPTNGGKCQPCKCN---GHASLCNT 1120 C + C++ G C+TC G++ + +N CQ C+C+ +S+C+ Sbjct: 639 VSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698 Query: 1121 NTGKCFCTTKGVKGDECQLCEVENRY 1146 +G C C + V G CQ EN Y Sbjct: 699 PSGVCQC-REHVVGKVCQ--RPENNY 721 Score = 41.6 bits (96), Expect = 0.006 Identities = 65/303 (21%), Positives = 96/303 (31%), Gaps = 95/303 (31%) Query: 909 CINPLNGSVCERPANHSAKQCRTPCALRTA---CGDCTSGSSECMWCSNMKQCVDSNAYV 965 C+ + VC N+ K R C T C C +G ++ W Sbjct: 299 CVCNGHAEVCN--INNPEKLFRCECQHHTCGETCDRCCTGYNQRRW-------------- 342 Query: 966 ASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQP----------------GCGWCTDPS 1009 + W C NC G+ S+C P G G C + Sbjct: 343 ------RPAAWEQSHECEACNCHGHA--SNCYYDPDVERQQASLNTQGIYAGGGVCINCQ 394 Query: 1010 NTGKG----KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQC 1065 + G +C +G Y+ P +P AP G C D H C+ Sbjct: 395 HNTAGVNCEQCAKGYYR-PYGVPVDAPDGCI---------PCSCDPE------HADGCE- 437 Query: 1066 NGHSKCINQSICEKCENLTTGKHCETCISGFYGDP-----------------TNGGKCQP 1108 G +C C+ G +CE C G+Y P G + Sbjct: 438 QGSGRC-------HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490 Query: 1109 CKCNGHA---SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQF 1165 C CN +C+ + G+C C GV+G C C + + P+ C+ + L YQ Sbjct: 491 CDCNLEGVLPEICDAH-GRCLC-RPGVEGPRCDTC--RSGFYSFPICQACWCSALGSYQM 546 Query: 1166 TFS 1168 S Sbjct: 547 PCS 549 Score = 40.4 bits (93), Expect = 0.012 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 9/84 (10%) Query: 245 YSFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEAC--------DIPHCTDNCGFPH 295 YSF +C CS G ++ SS T +CEC G+ C D PHC + Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587 Query: 296 RGICNSSDVRGCSCFSDWQGPGCS 319 +S++ C C +GP CS Sbjct: 588 PAGTINSNLGYCQCKLHVEGPTCS 611 Score = 40.4 bits (93), Expect = 0.012 Identities = 50/220 (22%), Positives = 70/220 (31%), Gaps = 46/220 (20%) Query: 915 GSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCM 974 G C N +QC T C G C CS ++ + GQC Sbjct: 1282 GGQCPCQPNVIGRQC-------TRCATGHYGFPRCKPCSCGRRLCEEMT-------GQCR 1327 Query: 975 EWYTMSTCPPENCSGYCTC--SHCLE---QPGCGWCTDPSNTGKGKCIEGSYKGPVKMPS 1029 CPP C +H GC C N + IE + MP Sbjct: 1328 -------CPPRTVRPQCEVCETHSFSFHPMAGCEGC----NCSRRGTIEAA------MPE 1370 Query: 1030 -QAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEK------CEN 1082 +G +P + C + + F C C CN +C+ C+ Sbjct: 1371 CDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT--EPGVCDPGTGACLCKE 1428 Query: 1083 LTTGKHCETCISG-FYGDPTNGGKCQPCKCNGHASLCNTN 1121 G C C G F+ DP N C C C G + C+++ Sbjct: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSS 1468 Score = 37.0 bits (84), Expect = 0.14 Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 10/59 (16%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFVTDGPGNYKYKTKC 158 C+R G C+PGTG C+C G +C C G F L P N K T C Sbjct: 1407 CNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL---------DPANLKGCTSC 1456 Score = 35.8 bits (81), Expect = 0.30 Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 5/45 (11%) Query: 100 ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGF 144 EC G C+P GQC C +G QC C TG GF Sbjct: 1267 ECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA-----TGHYGF 1306 Score = 32.0 bits (71), Expect = 4.4 Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 103 RPCVNGGR-CNPGTGQCVCPAGWVGEQCQHC 132 +PC G R C TGQC CP V QC+ C Sbjct: 1310 KPCSCGRRLCEEMTGQCRCPPRTVRPQCEVC 1340 Score = 31.6 bits (70), Expect = 5.7 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%) Query: 254 CSGRGE-CKISNSSDTVECECSENWKGEACD 283 C+G E C I+N CEC + GE CD Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCD 331 Score = 30.8 bits (68), Expect = 9.8 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 89 AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132 AV GS A C P N G N G +C C AG+ G QC+ C Sbjct: 1726 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769 >gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] Length = 1724 Score = 73.2 bits (178), Expect = 2e-12 Identities = 42/104 (40%), Positives = 57/104 (54%), Gaps = 11/104 (10%) Query: 1060 CPACQCNGHS-KCINQS-ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKC---NGH 1114 C C CNGHS +C + S IC C++ T G+HCE C G+YG+ + G C+ C C N Sbjct: 75 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNSF 133 Query: 1115 ASLCNTNTGKCFCTTK-GVKGDECQLCEVENRYQGNPLR--GTC 1155 A+ C N G C+ K G G +C+ C Y GNP + G+C Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 175 Score = 58.2 bits (139), Expect = 6e-08 Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 43/172 (25%) Query: 982 CPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFY 1037 C P NC+G+ + C Q G G C + + G +C EG Y V +A Sbjct: 75 CVPCNCNGHS--NQC--QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA-----C 125 Query: 1038 PQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KCINQSICEKCENLTTGKHCETCISGF 1096 P P NS C NG +C C+ TG CE C G+ Sbjct: 126 PCPHTNS--------------FATGCVVNGGDVRC-------SCKAGYTGTQCERCAPGY 164 Query: 1097 YGDPTN-GGKCQPCKCNGHASL--CNTNTGKCF-----CTTKGVKGDECQLC 1140 +G+P GG CQPC CN + L C+ TG C ++ + D+C C Sbjct: 165 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 216 Score = 53.9 bits (128), Expect = 1e-06 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 4/66 (6%) Query: 1092 CISGFYGDPTN--GGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGN 1149 C G+Y D G+C PC CNGH++ C +G C G+ C+ C + Y GN Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC--QEGYYGN 116 Query: 1150 PLRGTC 1155 + G+C Sbjct: 117 AVHGSC 122 Score = 30.8 bits (68), Expect = 9.8 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 89 AVSGSAAAEAKECDRPCVN----GGRCNPGTGQCVCPAGWVGEQCQHC 132 AV GS A C P N G N G +C C AG+ G QC+ C Sbjct: 117 AVHGSCRA----CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 160 >gi|145309326 laminin, gamma 1 precursor [Homo sapiens] Length = 1609 Score = 72.4 bits (176), Expect = 3e-12 Identities = 40/98 (40%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 1060 CPACQCNGHSK-CINQSICEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGHAS 1116 C C CNGHS+ C ++ C + T G HCE C G+YGD T G CQPC C G +S Sbjct: 721 CVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSS 780 Query: 1117 LCNT-NTGKCFCTT--KGVKGDECQLCEVENRYQGNPL 1151 T + CT G G C+LC ++ Y G+PL Sbjct: 781 CAVVPKTKEVVCTNCPTGTTGKRCELC--DDGYFGDPL 816 Score = 61.6 bits (148), Expect = 5e-09 Identities = 36/106 (33%), Positives = 48/106 (45%), Gaps = 16/106 (15%) Query: 1060 CPACQCNGHSKCI-----NQSICEKCENLTTGKHCETCISGFYGDP--TNG--GKCQPCK 1110 C C C G S C + +C C TTGK CE C G++GDP NG C+ C+ Sbjct: 770 CQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQ 829 Query: 1111 CNGH-----ASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPL 1151 C+ + CN TG+C G C C ++ + GNPL Sbjct: 830 CSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRC--KDGFFGNPL 873 Score = 59.3 bits (142), Expect = 3e-08 Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 27/163 (16%) Query: 991 CTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLED 1050 C CS ++ G C N G+C++ Y + G F+ PL + Sbjct: 828 CQCSDNIDPNAVGNC----NRLTGECLKCIYNTAGFYCDRCKDG-FFGNPLAPNPAD--- 879 Query: 1051 SRYNWSFIHCPACQCNGHSKCINQSICE----KCENL--TTGKHCETCISGFYGDPTNGG 1104 C AC CN + QS C +CE L TG+ C C GFY + +G Sbjct: 880 --------KCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFY-NLQSGQ 930 Query: 1105 KCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLCEVEN 1144 C+ C C+ S C+ TG+C C G+ G C+ CEV + Sbjct: 931 GCERCDCHALGSTNGQCDIRTGQCEC-QPGITGQHCERCEVNH 972 Score = 58.2 bits (139), Expect = 6e-08 Identities = 55/193 (28%), Positives = 70/193 (36%), Gaps = 36/193 (18%) Query: 981 TCPPENCSGYCTCSHCLEQPGCGWCTD----PSNTGKGK------CIEGSYKGPVKMPSQ 1030 TC PE +G C C P C C+D S G C GS V + Sbjct: 732 TCDPE--TGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKE 789 Query: 1031 APTGNFYPQPLLNSSMCLEDSRY-------NWSFIHCPACQC------NGHSKCINQS-I 1076 N P L D Y N C CQC N C + Sbjct: 790 VVCTNC-PTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGE 848 Query: 1077 CEKCENLTTGKHCETCISGFYGD---PTNGGKCQPCKCNGHASL-----CNTNTGKCFCT 1128 C KC T G +C+ C GF+G+ P KC+ C CN + ++ CN TG+C C Sbjct: 849 CLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECL 908 Query: 1129 TKGVKGDECQLCE 1141 V G +C C+ Sbjct: 909 PH-VTGQDCGACD 920 Score = 51.6 bits (122), Expect = 5e-06 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 1086 GKHCETCISGFYGDPTNGGKCQP---CKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEV 1142 G+ CE C+SG+ + N G P C CNGH+ C+ TG C C G C+ C Sbjct: 698 GQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNC-RDNTAGPHCEKC-- 754 Query: 1143 ENRYQGNPLRGT 1154 + Y G+ GT Sbjct: 755 SDGYYGDSTAGT 766 Score = 50.8 bits (120), Expect = 9e-06 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 15/95 (15%) Query: 1060 CPACQCNGHSK-CI----------NQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQP 1108 C C CNG S+ C + C C++ T G HCE C F+ N C Sbjct: 339 CLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFF-RLGNNEACSS 397 Query: 1109 CKCNGHASLCN--TNTGKCFCTTKGVKGDECQLCE 1141 C C+ SL + G+C C GV GD+C C+ Sbjct: 398 CHCSPVGSLSTQCDSYGRCSC-KPGVMGDKCDRCQ 431 Score = 50.4 bits (119), Expect = 1e-05 Identities = 55/244 (22%), Positives = 83/244 (34%), Gaps = 77/244 (31%) Query: 900 STRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCV 959 +T G+ C+ N R SA +C PC DC S EC + Sbjct: 310 NTYGVDCEKCLPFFNDRPWRRATAESASEC-LPC-------DCNGRSQECYF-------- 353 Query: 960 DSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEG 1019 D Y ++ G C NC +HC +C E Sbjct: 354 DPELYRSTGHGGHCT-----------NCQDNTDGAHC-----------------ERCREN 385 Query: 1020 SYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEK 1079 ++ L N+ C S + S + + QC+ + +C Sbjct: 386 FFR------------------LGNNEAC---SSCHCSPVGSLSTQCDSYGRC-------S 417 Query: 1080 CENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASL--CNTNTGKCFCTTKGVKGDEC 1137 C+ G C+ C GF+ G C+PC C+ S+ CN TG+C C V+G C Sbjct: 418 CKPGVMGDKCDRCQPGFHSLTEAG--CRPCSCDPSGSIDECNIETGRCVC-KDNVEGFNC 474 Query: 1138 QLCE 1141 + C+ Sbjct: 475 ERCK 478 Score = 49.7 bits (117), Expect = 2e-05 Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 11/89 (12%) Query: 1060 CPACQCNG----HSKC-INQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCN-- 1112 C C C+ + +C I CE C+ TG+HCE C +G G C+PC C+ Sbjct: 932 CERCDCHALGSTNGQCDIRTGQCE-CQPGITGQHCERCEVNHFGFGPEG--CKPCDCHPE 988 Query: 1113 GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141 G SL + G+C C +G G+ C CE Sbjct: 989 GSLSLQCKDDGRCEC-REGFVGNRCDQCE 1016 Score = 46.2 bits (108), Expect = 2e-04 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 24/116 (20%) Query: 1063 CQCNGH-SKCINQS----ICEKCENLTTGKHCETCISGFYGDP------TNGGKCQPCKC 1111 C+CNGH S+C+ +C C++ T G CE C+ F P + +C PC C Sbjct: 286 CKCNGHASECMKNEFDKLVCN-CKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC 344 Query: 1112 NGHASLC---------NTNTGKCFCTTKGVKGDECQLCEVEN--RYQGNPLRGTCY 1156 NG + C + G C G C+ C EN R N +C+ Sbjct: 345 NGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCR-ENFFRLGNNEACSSCH 399 Score = 33.5 bits (75), Expect = 1.5 Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 97 EAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 E +C G+C+ TGQC C G G+ C+ C Sbjct: 933 ERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERC 968 >gi|143770880 laminin, beta 4 [Homo sapiens] Length = 1761 Score = 72.0 bits (175), Expect = 4e-12 Identities = 77/267 (28%), Positives = 105/267 (39%), Gaps = 51/267 (19%) Query: 915 GSVCERPANHSAKQCRTPCALRTACGDCTSGSSE-----CMWCSNMKQCVDSNAYVASFP 969 GS C R QC+ P + C C++GS + C C Q S V Sbjct: 778 GSSCSRLGGQC--QCK-PLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQ--GSKDTVCDQV 832 Query: 970 FGQCMEWYTMSTCPPENC-SGY--------CTCSHCLE--QPGCGWCTDPSN--TGKG-- 1014 GQC +S + C +GY C C+ E P G C + TG+ Sbjct: 833 TGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCE 892 Query: 1015 KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQ 1074 +CI+G Y P P +C +D N F H +C N S + Sbjct: 893 RCIDGYYGNPSSGQPCRPC------------LCPDDPSSNQYFAH--SCYQNLWSSDV-- 936 Query: 1075 SICEKCENLTTGKHCETCISGFYGDPT-NGGKCQPCKCNGHASL-----CNTNTGKCFCT 1128 IC C TG C C +GFYG+P +G CQPC CN + + C+ TG+C Sbjct: 937 -ICN-CLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRC 994 Query: 1129 TKGVKGDECQLCEVENRYQGNPLRGTC 1155 +G CQLC + + G+ L TC Sbjct: 995 LHNTQGANCQLC--KPGHYGSALNQTC 1019 Score = 65.1 bits (157), Expect = 5e-10 Identities = 59/232 (25%), Positives = 87/232 (37%), Gaps = 45/232 (19%) Query: 937 TACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS---GYCT- 992 T CG+C++G N ++ P C + PE+CS G C Sbjct: 947 TQCGECSTGFY-------------GNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993 Query: 993 CSHCLEQPGCGWCTDPSNTGKG---KCIEGSYKGPVKMPSQAPTGN--FYPQPLLNSSMC 1047 C H + C C P + G C S P + P G P+ + C Sbjct: 994 CLHNTQGANCQLCK-PGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052 Query: 1048 LED---------SRYNWSFIHCPACQ-CNGHSKCINQSICEK------CENLTTGKHCET 1091 L + + W+ + CQ C+ + S C++ C+ GK C Sbjct: 1053 LPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE 1112 Query: 1092 CISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKGVKGDECQLC 1140 C +YGDP G+C PC CN + +C+ +TG C C +GV G C C Sbjct: 1113 CQENYYGDPP--GRCIPCDCNRAGTQKPICDPDTGMCRC-REGVSGQRCDRC 1161 Score = 59.3 bits (142), Expect = 3e-08 Identities = 44/188 (23%), Positives = 72/188 (38%), Gaps = 65/188 (34%) Query: 983 PPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLL 1042 PP G C C H + P C C D F+ Sbjct: 287 PPGMVHGQCVCQHNTDGPNCERCKD----------------------------FFQDAPW 318 Query: 1043 NSSMCLEDSRYNWSFIHCPACQCNGHS-KC------------INQSICEKCENLTTGKHC 1089 + L+D+ C +C CN HS +C ++ +CE C++ T G+HC Sbjct: 319 RPAADLQDNA-------CRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHC 371 Query: 1090 ETCISGFYGDP----TNGGKCQPCKCNGHAS----LCNTNT--------GKCFCTTKGVK 1133 + C FY DP ++ C PC+C+ + +C +++ G+C C + V+ Sbjct: 372 DRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLC-KENVE 430 Query: 1134 GDECQLCE 1141 G +C C+ Sbjct: 431 GAKCDQCK 438 Score = 45.8 bits (107), Expect = 3e-04 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 11/87 (12%) Query: 1060 CPACQCNGHSKC------INQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCN- 1112 C C CN ++ C C + TG HCE C G++G + C PC C+ Sbjct: 452 CQPCDCNPLGSLPFLTCDVDTGQC-LCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDI 510 Query: 1113 --GHASLCNTNTGKCFCTTKGVKGDEC 1137 ++++C+ G+C C V G C Sbjct: 511 GGAYSNVCSPKNGQCECRPH-VTGRSC 536 Score = 33.9 bits (76), Expect = 1.2 Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 100 ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 +CD C+ TGQC C G+ G++C C Sbjct: 1081 DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113 Score = 32.7 bits (73), Expect = 2.6 Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 100 ECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 +C+R C+P TG C C G G++C C Sbjct: 1129 DCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161 >gi|22547221 tolloid-like 1 [Homo sapiens] Length = 1013 Score = 72.0 bits (175), Expect = 4e-12 Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 27/167 (16%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWV----GEQCQHCGGRFRLTGSSGFVT--DGPGNYKY 154 C CVN G+ C C G+V C+ ++ SG +T + P Y Sbjct: 741 CQHECVN----TMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPS 796 Query: 155 KTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPER 210 + +CTW I P ++L F+ F E C++DHL V+DG++ +P++ G +P+ Sbjct: 797 RKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPD- 855 Query: 211 DGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGR 257 +VAT + F SDA+ GF T+S C GR Sbjct: 856 -------PLVATGNKMFVRFVSDASVQRKGFQATHS-----TECGGR 890 Score = 58.5 bits (140), Expect = 4e-08 Identities = 46/167 (27%), Positives = 67/167 (40%), Gaps = 15/167 (8%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLY 187 CGG R + P +Y+ +C W I + + L F F E C++D+L Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521 Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF--NITY 245 V DG S +PL+ F G PE ++ +TS + F SD N GF N Sbjct: 522 VRDGTSENSPLIGRFCGYDKPE--------DIRSTSNTLWMKFVSDGTVNKAGFAANFFK 573 Query: 246 SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292 D C G E + N+ + +C C ++ D C CG Sbjct: 574 EEDECAKPDRGGCEQRCLNTLGSYQCACEPGYE-LGPDRRSCEAACG 619 Score = 49.7 bits (117), Expect = 2e-05 Identities = 34/131 (25%), Positives = 51/131 (38%), Gaps = 16/131 (12%) Query: 123 GWVGEQCQHCGGRFRLTGSS----GFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFA 178 G+ CGGR + G NY + C WL+ + + L F F Sbjct: 878 GFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFE 937 Query: 179 TE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDA 234 E C +D++ ++DG A + F G PE E+ + L+HF +D Sbjct: 938 VEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPE--------EIYSIGDSVLIHFHTDD 989 Query: 235 AYNLTGFNITY 245 N GF+I Y Sbjct: 990 TINKKGFHIRY 1000 Score = 44.7 bits (104), Expect = 7e-04 Identities = 49/189 (25%), Positives = 76/189 (40%), Gaps = 34/189 (17%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAGWV----GEQCQH-CGGRFRLTGSSGFVTDG--PGNYK 153 C++ C+N G+ QC C G+ C+ CGG LT +G +T P Y Sbjct: 586 CEQRCLN----TLGSYQCACEPGYELGPDRRSCEAACGGL--LTKLNGTITTPGWPKEYP 639 Query: 154 YKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPE 209 C W + + ++F F E C +D++ ++ G S + L F G VPE Sbjct: 640 PNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPE 699 Query: 210 RDGNETVPEVVATSGY--ALLHFFSDAAYNLTGFNITYSFDMCPNNCS-GRGEC--KISN 264 V TS + + F SD + GF + D + CS G C + N Sbjct: 700 ----------VITSQFNNMRIEFKSDNTVSKKGFKAHFFSD--KDECSKDNGGCQHECVN 747 Query: 265 SSDTVECEC 273 + + C+C Sbjct: 748 TMGSYMCQC 756 Score = 36.6 bits (83), Expect = 0.18 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 13/94 (13%) Query: 120 CPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFN---- 175 CPA GE Q G S GF P Y T C W + P + L F Sbjct: 346 CPA--CGETLQESNGNL---SSPGF----PNGYPSYTHCIWRVSVTPGEKIVLNFTTMDL 396 Query: 176 HFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPE 209 + ++ C +D++ V DG +PL+ F G +PE Sbjct: 397 YKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPE 430 >gi|6912724 tolloid-like 2 [Homo sapiens] Length = 1015 Score = 70.9 bits (172), Expect = 9e-12 Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 29/195 (14%) Query: 101 CDRPCVNGGRCNPGTGQCVCPAG-WV---GEQCQHCGGRFRLTGSSGFVT--DGPGNYKY 154 C CVN G+ C C G W+ G C+ G +++ G + + P Y Sbjct: 743 CQHECVN----TFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPS 798 Query: 155 KTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPER 210 + +CTW I ++L FN F E C++DHL +YDG AP++ F G P+ Sbjct: 799 RRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPD- 857 Query: 211 DGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVE 270 VA+ L F+SDA+ GF +S C GR + ++ Sbjct: 858 -------PTVASGSSMFLRFYSDASVQRKGFQAVHS-----TECGGRLKAEVQTKELYSH 905 Query: 271 CECSE-NWKGEA-CD 283 + + N+ EA CD Sbjct: 906 AQFGDNNYPSEARCD 920 Score = 51.6 bits (122), Expect = 5e-06 Identities = 44/167 (26%), Positives = 66/167 (39%), Gaps = 15/167 (8%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLY 187 CGG + P +Y+ +C W I + L F F E C++D+L Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523 Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF--NITY 245 V DG + + L+ F G PE +V ++S + F SD + N GF N Sbjct: 524 VRDGPTEESALIGHFCGYEKPE--------DVKSSSNRLWMKFVSDGSINKAGFAANFFK 575 Query: 246 SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292 D C G E + N+ + +C C ++ A D C CG Sbjct: 576 EVDECSWPDHGGCEHRCVNTLGSYKCACDPGYE-LAADKKMCEVACG 621 Score = 47.0 bits (110), Expect = 1e-04 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 16/132 (12%) Query: 123 GWVGEQCQHCGGRFRLTGSS----GFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFA 178 G+ CGGR + + G NY + +C W+I + + L F F Sbjct: 880 GFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFE 939 Query: 179 TE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDA 234 E C +D++ YDG AP + F G+ + E+ + ++ F +D Sbjct: 940 VEEEADCGYDYMEAYDGYDSSAPRLGRFC--------GSGPLEEIYSAGDSLMIRFRTDD 991 Query: 235 AYNLTGFNITYS 246 N GF+ Y+ Sbjct: 992 TINKKGFHARYT 1003 Score = 36.6 bits (83), Expect = 0.18 Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 13/94 (13%) Query: 120 CPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHF-- 177 CPA GE Q G F G P Y + C W I P + L F Sbjct: 348 CPA--CGETLQDTTGNFSAPGF-------PNGYPSYSHCVWRISVTPGEKIVLNFTSMDL 398 Query: 178 --ATECSWDHLYVYDGDSIYAPLVAAFSGLIVPE 209 + C +D++ V DG APL+ F G +PE Sbjct: 399 FKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPE 432 >gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] Length = 3487 Score = 70.5 bits (171), Expect = 1e-11 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 12/116 (10%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG LT SG + PG YK C W+IE QP +++ F+ F TE ++D L V Sbjct: 752 CGGH--LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVR 809 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG + APL+ + G VP+ +++TS Y L F +D +++ GF + Y Sbjct: 810 DGRTYSAPLIGVYHGTQVPQ--------FLISTSNYLYLLFSTDKSHSDIGFQLRY 857 Score = 67.4 bits (163), Expect = 9e-11 Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 11/123 (8%) Query: 131 HCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188 HC LT S+G + PG+Y C+WL+ +P+ + L +F +E +D + Sbjct: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413 Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNITYSF 247 +DG S +PL+ A S GN + P +V +S ++ L + SD AYN GF I YS Sbjct: 2414 FDGPSGQSPLLKALS--------GNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465 Query: 248 DMC 250 C Sbjct: 2466 PYC 2468 Score = 60.5 bits (145), Expect = 1e-08 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 22/136 (16%) Query: 113 PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIM 170 P C+ P CGG LTG SG + P Y +C W + P+ ++ Sbjct: 1436 PSPPTCIAP----------CGGD--LTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483 Query: 171 RLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHF 230 L FN F E +D L++YDG +PL+ +F G +P R + ++S L F Sbjct: 1484 ALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGR--------IESSSNSLFLAF 1535 Query: 231 FSDAAYNLTGFNITYS 246 SDA+ + GF I Y+ Sbjct: 1536 RSDASVSNAGFVIDYT 1551 Score = 56.6 bits (135), Expect = 2e-07 Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 15/123 (12%) Query: 136 FRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDS 193 F T SG V P +Y C WLI +P + L FN E +D L + DG + Sbjct: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGAT 639 Query: 194 IYAPLVAAFSGLIVPERDGNETVPEVVATSGY-ALLHFFSDAAYNLTGFNITYS---FDM 249 AP++ FSG +P + +SG+ A L F +D + GFNIT++ + Sbjct: 640 AEAPVLGTFSG---------NQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNE 690 Query: 250 CPN 252 CP+ Sbjct: 691 CPD 693 Score = 56.2 bits (134), Expect = 2e-07 Identities = 42/158 (26%), Positives = 64/158 (40%), Gaps = 16/158 (10%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + P Y C W I ++++ F TE +WD L V+DG Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDG 1855 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY---SFD 248 ++ +FSG VP + +TS LHF+SD + + GF++ Y Sbjct: 1856 ADNTVTMLGSFSGTTVPAL--------LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLS 1907 Query: 249 MC-----PNNCSGRGECKISNSSDTVECECSENWKGEA 281 C P+N GE + N + +CE +G A Sbjct: 1908 SCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHA 1945 Score = 47.8 bits (112), Expect = 8e-05 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 17/159 (10%) Query: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190 CGG R S ++ G P Y++ C W IE + + L F F TE D L ++D Sbjct: 1271 CGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWD 1330 Query: 191 GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250 G SG+++ E G ++ +T +L F +D + GF I +S Sbjct: 1331 G--------PVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTA 1382 Query: 251 --------PNNCSGRGECKISNSSDTVECECSENWKGEA 281 P N S G+ + S +C+ +G A Sbjct: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSA 1421 Score = 45.1 bits (105), Expect = 5e-04 Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 16/130 (12%) Query: 130 QHCGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHL 186 Q+C F+L G +G V + PG Y CTW I + ++L F FA E +D L Sbjct: 24 QNC--TFQLHGPNGTV-ESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVL 80 Query: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS 246 V+DG L +G +P +V+ + L SD A + GF+ TY Sbjct: 81 SVFDGPPQPENLRTRLTGFQLP--------ATIVSAATTLSLRLISDYAVSAQGFHATY- 131 Query: 247 FDMCPNNCSG 256 ++ P++ G Sbjct: 132 -EVLPSHTCG 140 Score = 44.7 bits (104), Expect = 7e-04 Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 26/143 (18%) Query: 111 CNPGTGQ--------CVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLI 162 C PGT + C+ G E+ + + S GF PGNY C+W I Sbjct: 1949 CMPGTVRRWNYPPPLCIAQCGGTVEEMEG------VILSPGF----PGNYPSNMDCSWKI 1998 Query: 163 EGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVAT 222 ++F +F+TE + D++ + +G + ++ FSG +P +++T Sbjct: 1999 ALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPS--------SLLST 2050 Query: 223 SGYALLHFFSDAAYNLTGFNITY 245 S ++F SD + N GF + Y Sbjct: 2051 SHETTVYFHSDHSQNRPGFKLEY 2073 Score = 43.5 bits (101), Expect = 0.001 Identities = 49/178 (27%), Positives = 68/178 (38%), Gaps = 23/178 (12%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV- 188 CGG R G SG ++ P Y CTW I + + L F F E +D L V Sbjct: 202 CGGTLR--GQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259 Query: 189 -YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSF 247 +G S++ F+G +P V+++ + LHF SD + GF+ Y Sbjct: 260 GTEGSSLW------FTGASLP--------APVISSKNWLRLHFTSDGNHRQRGFSAQYQV 305 Query: 248 DMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVR 305 RG K+ S D + G + C D G P RG SD R Sbjct: 306 KK-QIELKSRG-VKLMPSKDNSQKTSVLTQVGVSQGHNMCPDP-GIPERGKRLGSDFR 360 Score = 43.5 bits (101), Expect = 0.001 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 19/127 (14%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG + GSSG + P Y CTW+IE + + F+ F E D+L + Sbjct: 924 CGGFIQ--GSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLIT 981 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGY----ALLHFFSDAAYNLTGFNITY 245 + S PL + +P ++ Y A + F SD + + GFNIT+ Sbjct: 982 ENGSFTQPL----------RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITF 1031 Query: 246 S-FDMCP 251 S +D+ P Sbjct: 1032 SEYDLEP 1038 Score = 42.4 bits (98), Expect = 0.003 Identities = 48/188 (25%), Positives = 66/188 (35%), Gaps = 39/188 (20%) Query: 92 GSAAAEAKECDRP------CVNGGRCNPG---TGQCVCPAGWVGEQ---CQH-------- 131 G A E +EC P V G N G T +C+ G CQH Sbjct: 2114 GCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDH 2173 Query: 132 --------CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSW 183 CGG + + + P Y C WLI +RL + TE S Sbjct: 2174 PLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSG 2233 Query: 184 DHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI 243 D + ++DG AP + F+ + + V ++S LL F DAA TG Sbjct: 2234 DFITIWDGPQQTAPRLGVFTRSMAKK--------TVQSSSNQVLLKFHRDAA---TGGIF 2282 Query: 244 TYSFDMCP 251 +F P Sbjct: 2283 AIAFSAYP 2290 Score = 40.0 bits (92), Expect = 0.016 Identities = 46/178 (25%), Positives = 66/178 (37%), Gaps = 16/178 (8%) Query: 76 LLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAG----WVGE--QC 129 L PCE A + G C G R GT + C G W +C Sbjct: 1036 LEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLE-GTARITCLGGRRRLWSSPLPRC 1094 Query: 130 -QHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188 CG T + + P NY +C + I+ QP + ++L+ F D L V Sbjct: 1095 VAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELS-EGDVLKV 1153 Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS 246 YDG++ A L+ FS + +TS L F +DA GF + +S Sbjct: 1154 YDGNNNSARLLGVFS-------HSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFS 1204 >gi|219842266 usherin isoform B [Homo sapiens] Length = 5202 Score = 69.3 bits (168), Expect = 2e-11 Identities = 69/264 (26%), Positives = 97/264 (36%), Gaps = 48/264 (18%) Query: 928 QCRTPCALRTACGDCTSGSSECMWCSNMKQC--VDSNAYVASFPFGQCMEWYTMSTCPPE 985 QC ++ C SG EC + QC N Y + + T + P Sbjct: 748 QCNLHGSVNKFCNP-HSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806 Query: 986 NCS---GYCTCSHCLEQPGCGWCTD--------------PSNTGKGKCIEGSYKGPVKMP 1028 C+ G C C +E C C + P N K I GS K Sbjct: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN-KST 865 Query: 1029 SQAP-----TGNFYPQPLLNSSMCLEDSRYNWS---FIHCPACQCNGHSKCINQSICEK- 1079 Q P TG L + C E RYN + F HC C+C+ + +IC+ Sbjct: 866 GQCPCKLGVTG-------LRCNQC-EPHRYNLTIDNFQHCQMCECDSLGT-LPGTICDPI 916 Query: 1080 -----CENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKG 1131 C G+ C C GFY P N C PC C+ + +CN+ TG+C C Sbjct: 917 SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976 Query: 1132 VKGDECQLCEVENRYQGNPLRGTC 1155 + G C C+ ++ + +P G C Sbjct: 977 IAGQRCDQCK-DHYFGFDPQTGRC 999 Score = 62.0 bits (149), Expect = 4e-09 Identities = 66/254 (25%), Positives = 96/254 (37%), Gaps = 42/254 (16%) Query: 909 CINPLNGSVCERPANHSAKQCRTPCALRTACGDC---TSGSSE-CMWCSNMKQCVDSNAY 964 C + G CE ++ +Q + C C T G+ + C + + + Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667 Query: 965 VASFPFGQCME-WYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKG 1023 V+ QC +Y + P+ CS C C+ G C N+G+ KC + + G Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSP-CNCNTSGTVDGDITCHQ--NSGQCKC-KANVIG 723 Query: 1024 PVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSF--IHCPACQCNGHSK----CINQSIC 1077 L C ++ SF + C CQCN H C S Sbjct: 724 ------------------LRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765 Query: 1078 EKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASL----CNTNTGKCFCTTKGV 1132 +C+ G C+TC FYG D TN C+ C C+ SL CN TG+C C V Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGTVCNAKTGQCIC-KPNV 821 Query: 1133 KGDECQLCEVENRY 1146 +G +C C N Y Sbjct: 822 EGRQCNKCLEGNFY 835 Score = 61.2 bits (147), Expect = 7e-09 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 26/108 (24%) Query: 1059 HCPACQCNGHSKCINQSI----------------CEKCENLTTGKHCETCISGFY----G 1098 +C CQCN HSK + +I C+ CE+ TTG++CE C F+ Sbjct: 571 NCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630 Query: 1099 DPTNGGKCQPCKCN-----GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141 DP+ C+PC C+ + LC+ G+C C + V G +C C+ Sbjct: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNC-KRHVSGRQCNQCQ 677 Score = 53.9 bits (128), Expect = 1e-06 Identities = 58/236 (24%), Positives = 85/236 (36%), Gaps = 63/236 (26%) Query: 913 LNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQ 972 +NGS+ N S QC PC L C C + N + +F Q Sbjct: 855 INGSLL---CNKSTGQC--PCKLGVT-------GLRCNQCEPHRY----NLTIDNFQHCQ 898 Query: 973 CMEWYTMSTCPPENC---SGYCTCSHCLEQPGCGWCTDPSNTGK--GKCIEGSYKGPVKM 1027 E ++ T P C SG C C P+ G+ +C G Y P Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCV-------------PNRQGRRCNQCQPGFYISPG-- 943 Query: 1028 PSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGK 1087 N++ CL S + ++ G C + SI G+ Sbjct: 944 ---------------NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA--------GQ 980 Query: 1088 HCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLC 1140 C+ C ++G G+CQPC C+ +L C+ TG+CFC + V G +C C Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFC-KQFVTGSKCDAC 1035 Score = 51.6 bits (122), Expect = 5e-06 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 25/104 (24%) Query: 1063 CQCNGHS-KCINQSICEKC----ENLTTGKHCETCISGFYGDPTNGG------KCQPCKC 1111 CQC+GH+ C S +C E+ T G HC+ C+ + P G C+PC+C Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 Query: 1112 NGHASLCNTNT--------------GKCFCTTKGVKGDECQLCE 1141 N H+ C+ N G C G C+LC+ Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCK 621 Score = 38.9 bits (89), Expect = 0.036 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 13/136 (9%) Query: 224 GYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECE-CSENWKGEAC 282 G+ L F+D N+ S + N SG+ ECK + ++C+ C EN+ G Sbjct: 732 GFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK--KEAKGLQCDTCRENFYG--L 787 Query: 283 DIPHC----TDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338 D+ +C D G +CN+ + C C + +G C+ + N F+ R+ S L Sbjct: 788 DVTNCKACDCDTAGSLPGTVCNAKTGQ-CICKPNVEGRQCNKCLEGN--FYLRQNNSFLC 844 Query: 339 LP-RASHKAVVNGNIM 353 LP +NG+++ Sbjct: 845 LPCNCDKTGTINGSLL 860 Score = 36.2 bits (82), Expect = 0.23 Identities = 62/239 (25%), Positives = 89/239 (37%), Gaps = 53/239 (22%) Query: 97 EAKECDRP-CVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFV-----TDGP 149 +A +CD + G CN TGQC+C G QC C G F L ++ F+ D Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852 Query: 150 GNYKYKTKCTWLIEGQPNR--IMRLRFN------HFATECSWDHLYVYDGDS---IYAPL 198 G C P + + LR N + T ++ H + + DS + + Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912 Query: 199 VAAFSG--LIVPERDG---NETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNN 253 SG L VP R G N+ P + G N TG P + Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFYISPG------------NATG--------CLPCS 952 Query: 254 CSGRGECKISNSSDTVECECSE-NWKGEACDIPHCTDN-CGF-PHRGICNSSDVRGCSC 309 C G +S T +C C + + G+ CD C D+ GF P G C + C+C Sbjct: 953 CHTTGAVNHICNSLTGQCVCQDASIAGQRCD--QCKDHYFGFDPQTGRC-----QPCNC 1004 Score = 33.1 bits (74), Expect = 2.0 Identities = 12/31 (38%), Positives = 17/31 (54%) Query: 111 CNPGTGQCVCPAGWVGEQCQHCGGRFRLTGS 141 C+ +GQC C A +G +C HC F+ S Sbjct: 708 CHQNSGQCKCKANVIGLRCDHCNFGFKFLRS 738 >gi|219842259 usherin isoform A [Homo sapiens] Length = 1546 Score = 69.3 bits (168), Expect = 2e-11 Identities = 69/264 (26%), Positives = 97/264 (36%), Gaps = 48/264 (18%) Query: 928 QCRTPCALRTACGDCTSGSSECMWCSNMKQC--VDSNAYVASFPFGQCMEWYTMSTCPPE 985 QC ++ C SG EC + QC N Y + + T + P Sbjct: 748 QCNLHGSVNKFCNP-HSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGT 806 Query: 986 NCS---GYCTCSHCLEQPGCGWCTD--------------PSNTGKGKCIEGSYKGPVKMP 1028 C+ G C C +E C C + P N K I GS K Sbjct: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN-KST 865 Query: 1029 SQAP-----TGNFYPQPLLNSSMCLEDSRYNWS---FIHCPACQCNGHSKCINQSICEK- 1079 Q P TG L + C E RYN + F HC C+C+ + +IC+ Sbjct: 866 GQCPCKLGVTG-------LRCNQC-EPHRYNLTIDNFQHCQMCECDSLGT-LPGTICDPI 916 Query: 1080 -----CENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHAS---LCNTNTGKCFCTTKG 1131 C G+ C C GFY P N C PC C+ + +CN+ TG+C C Sbjct: 917 SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976 Query: 1132 VKGDECQLCEVENRYQGNPLRGTC 1155 + G C C+ ++ + +P G C Sbjct: 977 IAGQRCDQCK-DHYFGFDPQTGRC 999 Score = 62.0 bits (149), Expect = 4e-09 Identities = 66/254 (25%), Positives = 96/254 (37%), Gaps = 42/254 (16%) Query: 909 CINPLNGSVCERPANHSAKQCRTPCALRTACGDC---TSGSSE-CMWCSNMKQCVDSNAY 964 C + G CE ++ +Q + C C T G+ + C + + + Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667 Query: 965 VASFPFGQCME-WYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKG 1023 V+ QC +Y + P+ CS C C+ G C N+G+ KC + + G Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSP-CNCNTSGTVDGDITCHQ--NSGQCKC-KANVIG 723 Query: 1024 PVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSF--IHCPACQCNGHSK----CINQSIC 1077 L C ++ SF + C CQCN H C S Sbjct: 724 ------------------LRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765 Query: 1078 EKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASL----CNTNTGKCFCTTKGV 1132 +C+ G C+TC FYG D TN C+ C C+ SL CN TG+C C V Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGTVCNAKTGQCIC-KPNV 821 Query: 1133 KGDECQLCEVENRY 1146 +G +C C N Y Sbjct: 822 EGRQCNKCLEGNFY 835 Score = 61.2 bits (147), Expect = 7e-09 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 26/108 (24%) Query: 1059 HCPACQCNGHSKCINQSI----------------CEKCENLTTGKHCETCISGFY----G 1098 +C CQCN HSK + +I C+ CE+ TTG++CE C F+ Sbjct: 571 NCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630 Query: 1099 DPTNGGKCQPCKCN-----GHASLCNTNTGKCFCTTKGVKGDECQLCE 1141 DP+ C+PC C+ + LC+ G+C C + V G +C C+ Sbjct: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNC-KRHVSGRQCNQCQ 677 Score = 53.9 bits (128), Expect = 1e-06 Identities = 58/236 (24%), Positives = 85/236 (36%), Gaps = 63/236 (26%) Query: 913 LNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQ 972 +NGS+ N S QC PC L C C + N + +F Q Sbjct: 855 INGSLL---CNKSTGQC--PCKLGVT-------GLRCNQCEPHRY----NLTIDNFQHCQ 898 Query: 973 CMEWYTMSTCPPENC---SGYCTCSHCLEQPGCGWCTDPSNTGK--GKCIEGSYKGPVKM 1027 E ++ T P C SG C C P+ G+ +C G Y P Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCV-------------PNRQGRRCNQCQPGFYISPG-- 943 Query: 1028 PSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGK 1087 N++ CL S + ++ G C + SI G+ Sbjct: 944 ---------------NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIA--------GQ 980 Query: 1088 HCETCISGFYGDPTNGGKCQPCKCNGHASL---CNTNTGKCFCTTKGVKGDECQLC 1140 C+ C ++G G+CQPC C+ +L C+ TG+CFC + V G +C C Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFC-KQFVTGSKCDAC 1035 Score = 51.6 bits (122), Expect = 5e-06 Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 25/104 (24%) Query: 1063 CQCNGHS-KCINQSICEKC----ENLTTGKHCETCISGFYGDPTNGG------KCQPCKC 1111 CQC+GH+ C S +C E+ T G HC+ C+ + P G C+PC+C Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577 Query: 1112 NGHASLCNTNT--------------GKCFCTTKGVKGDECQLCE 1141 N H+ C+ N G C G C+LC+ Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCK 621 Score = 38.9 bits (89), Expect = 0.036 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 13/136 (9%) Query: 224 GYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECE-CSENWKGEAC 282 G+ L F+D N+ S + N SG+ ECK + ++C+ C EN+ G Sbjct: 732 GFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK--KEAKGLQCDTCRENFYG--L 787 Query: 283 DIPHC----TDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338 D+ +C D G +CN+ + C C + +G C+ + N F+ R+ S L Sbjct: 788 DVTNCKACDCDTAGSLPGTVCNAKTGQ-CICKPNVEGRQCNKCLEGN--FYLRQNNSFLC 844 Query: 339 LP-RASHKAVVNGNIM 353 LP +NG+++ Sbjct: 845 LPCNCDKTGTINGSLL 860 Score = 36.2 bits (82), Expect = 0.23 Identities = 62/239 (25%), Positives = 89/239 (37%), Gaps = 53/239 (22%) Query: 97 EAKECDRP-CVNGGRCNPGTGQCVCPAGWVGEQCQHC-GGRFRLTGSSGFV-----TDGP 149 +A +CD + G CN TGQC+C G QC C G F L ++ F+ D Sbjct: 793 KACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKT 852 Query: 150 GNYKYKTKCTWLIEGQPNR--IMRLRFN------HFATECSWDHLYVYDGDS---IYAPL 198 G C P + + LR N + T ++ H + + DS + + Sbjct: 853 GTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI 912 Query: 199 VAAFSG--LIVPERDG---NETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNN 253 SG L VP R G N+ P + G N TG P + Sbjct: 913 CDPISGQCLCVPNRQGRRCNQCQPGFYISPG------------NATG--------CLPCS 952 Query: 254 CSGRGECKISNSSDTVECECSE-NWKGEACDIPHCTDN-CGF-PHRGICNSSDVRGCSC 309 C G +S T +C C + + G+ CD C D+ GF P G C + C+C Sbjct: 953 CHTTGAVNHICNSLTGQCVCQDASIAGQRCD--QCKDHYFGFDPQTGRC-----QPCNC 1004 Score = 33.1 bits (74), Expect = 2.0 Identities = 12/31 (38%), Positives = 17/31 (54%) Query: 111 CNPGTGQCVCPAGWVGEQCQHCGGRFRLTGS 141 C+ +GQC C A +G +C HC F+ S Sbjct: 708 CHQNSGQCKCKANVIGLRCDHCNFGFKFLRS 738 >gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] Length = 1044 Score = 68.9 bits (167), Expect = 3e-11 Identities = 68/253 (26%), Positives = 96/253 (37%), Gaps = 35/253 (13%) Query: 104 PCVNGGRCNPGTGQCVCPAGWVGEQC-QHCG-GRFRLTGSSGFVTDGPGNYKYKT-KCTW 160 PC NGG C+ TG+C CP GW G C Q C G F S G + T +C Sbjct: 233 PCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHC 292 Query: 161 LIEGQPNRIMR-LRFNHFATECSWDHLYVYDGDSIYAPLVAA------FSGLIVPERDGN 213 +R F F +CS H ++G +P A + G ER Sbjct: 293 TAGYMGDRCQEECPFGSFGFQCS-QHCDCHNGGQC-SPTTGACECEPGYKGPRCQERLCP 350 Query: 214 E-------TVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRG---ECKIS 263 E T+P H + A G++ + + CP G G C Sbjct: 351 EGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ 410 Query: 264 NSSD----TVECECSENWKGEACDI--------PHCTDNCGFPHRGICNSSDVRGCSCFS 311 N +D T C C+ + GE C + P+C+ C + G C+ D C+C Sbjct: 411 NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVD-GSCTCKE 469 Query: 312 DWQGPGCSVPVPA 324 WQG C++P P+ Sbjct: 470 GWQGLDCTLPCPS 482 Score = 54.3 bits (129), Expect = 8e-07 Identities = 71/265 (26%), Positives = 97/265 (36%), Gaps = 56/265 (21%) Query: 908 TCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQC--VDSNAYV 965 TC +P++GS C C PC T +C +E C+N C +D + Sbjct: 457 TC-SPVDGS-CTCKEGWQGLDCTLPCPSGTWGLNC----NESCTCANGAACSPIDGSCSC 510 Query: 966 ASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPV 1025 G E NCS +C CSH GC DP TG C+ G + G + Sbjct: 511 TPGWLGDTCELPCPDGTFGLNCSEHCDCSHA---DGC----DPV-TGHCCCLAG-WTG-I 560 Query: 1026 KMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTT 1085 + S P G + P N S+ +C C C + +C Sbjct: 561 RCDSTCPPGRWGP----NCSV---------------SCSCENGGSCSPEDGSCECAPGFR 601 Query: 1086 GKHCE-TCISGFYGDPTNGGKCQPCKCNGHASL-CNTNTGKCFC------------TTKG 1131 G C+ C GFYG G QPC H+S C+ +G C C G Sbjct: 602 GPLCQRICPPGFYGH----GCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGG 657 Query: 1132 VKGDEC-QLCEVENRYQGNPLRGTC 1155 G +C QLC N +P+ G+C Sbjct: 658 YFGQDCAQLCSCANNGTCSPIDGSC 682 Score = 52.0 bits (123), Expect = 4e-06 Identities = 66/261 (25%), Positives = 89/261 (34%), Gaps = 59/261 (22%) Query: 909 CINPLNGSVCER--PANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDS----- 961 C G +C+R P C PC L C S C S + +C+ Sbjct: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCPL------CVHSSRPCHHISGICECLPGFSGAL 649 Query: 962 -NAYVASFPFGQ-CMEWYTMS---TCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKG-- 1014 N A FGQ C + + + TC P G C C C P G Sbjct: 650 CNQVCAGGYFGQDCAQLCSCANNGTCSP--IDGSCQCFPGWIGKDCSQACPPGFWGPACF 707 Query: 1015 ---KCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPA--------- 1062 C G+ A G + P C + CPA Sbjct: 708 HACSCHNGA-------SCSAEDGACHCTPGWTGLFCTQ---------RCPAAFFGKDCGR 751 Query: 1063 -CQCNGHSKCINQSICEKCENLTTGKHCE-TCISGFYGDPTNGGKCQPCKCNGHASLCNT 1120 CQC + C + S C TG+HCE C G +G G Q C+C + S C+ Sbjct: 752 VCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFG----YGCQQLCECMNN-STCDH 806 Query: 1121 NTGKCFCTT--KGVKGDECQL 1139 TG C+C+ KG++ D+ L Sbjct: 807 VTGTCYCSPGFKGIRCDQAAL 827 Score = 48.5 bits (114), Expect = 5e-05 Identities = 64/243 (26%), Positives = 81/243 (33%), Gaps = 65/243 (26%) Query: 941 DCTSGSSECMW---CSNMKQCVDSNAYVASFPFGQCM------EWYTMSTCPP----ENC 987 DC+SG W CSN QC N + + G C+ W C P + C Sbjct: 128 DCSSGCDSDHWGPHCSNRCQC--QNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGC 185 Query: 988 SGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMC 1047 C C H G DP G+ C G Y G + +C Sbjct: 186 QLPCQCRH-------GASCDP-RAGECLCAPG-YTG-----------------VYCEELC 219 Query: 1048 LEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC-ETCISGFYGDPTNGGKC 1106 S + CP CQ G I C TG C + C G +G + Sbjct: 220 PPGSHGAHCELRCP-CQNGGTCHHITGECA--CPPGWTGAVCAQPCPPGTFGQNCS---- 272 Query: 1107 QPCKCNGHASLCNTNTGKCFCTTKGVKGDEC--------------QLCEVENRYQGNPLR 1152 Q C C+ H C+ TG+C CT G GD C Q C+ N Q +P Sbjct: 273 QDCPCH-HGGQCDHVTGQCHCTA-GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTT 330 Query: 1153 GTC 1155 G C Sbjct: 331 GAC 333 Score = 47.4 bits (111), Expect = 1e-04 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 11/81 (13%) Query: 253 NCSGRGECKISNSSDTVE--CECSENWKGEACDIP--------HCTDNCGFPHRGICNSS 302 NCS C + V+ C C E W+G C +P +C ++C + C+ Sbjct: 445 NCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPI 504 Query: 303 DVRGCSCFSDWQGPGCSVPVP 323 D CSC W G C +P P Sbjct: 505 D-GSCSCTPGWLGDTCELPCP 524 Score = 44.7 bits (104), Expect = 7e-04 Identities = 54/229 (23%), Positives = 75/229 (32%), Gaps = 47/229 (20%) Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEG 164 C NG CNP TG CVC AG+ G +C+ G+ G P ++ C Sbjct: 148 CQNGALCNPITGACVCAAGFRGWRCE----ELCAPGTHGKGCQLPCQCRHGASC------ 197 Query: 165 QPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSG 224 + A EC Y +Y L P G +G Sbjct: 198 ----------DPRAGECLCAPGYT----GVYC------EELCPPGSHGAHCELRCPCQNG 237 Query: 225 YALLHFFSDAAYNLTGFNITYSFDMCP-----NNCSGRGECKISNSSD--TVECECSENW 277 H + A G+ CP NCS C D T +C C+ + Sbjct: 238 GTCHHITGECACP-PGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGY 296 Query: 278 KGEAC--DIP------HCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGC 318 G+ C + P C+ +C + G C S C C ++GP C Sbjct: 297 MGDRCQEECPFGSFGFQCSQHCDCHNGGQC-SPTTGACECEPGYKGPRC 344 Score = 42.4 bits (98), Expect = 0.003 Identities = 55/247 (22%), Positives = 75/247 (30%), Gaps = 56/247 (22%) Query: 99 KECDRPCV--NGGRCNPGTGQCVCPAGWVGEQCQ----------HCGGRFRLTGSSGFVT 146 K C PC +G C+P G+C+C G+ G C+ HC R + G Sbjct: 183 KGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQ-NGGTCH 241 Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206 G T + QP F CS D + G Sbjct: 242 HITGECACPPGWTGAVCAQP-----CPPGTFGQNCSQDCPCHHGGQC------------- 283 Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSS 266 + + T+GY + + GF + D C G+C S Sbjct: 284 ------DHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD-----CHNGGQC----SP 328 Query: 267 DTVECECSENWKGEACDI---------PHCTDNCGFPHRGICNSSDVRG-CSCFSDWQGP 316 T CEC +KG C P CT C + V G C+C W G Sbjct: 329 TTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGH 388 Query: 317 GCSVPVP 323 C+ P Sbjct: 389 HCNESCP 395 Score = 40.8 bits (94), Expect = 0.009 Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%) Query: 98 AKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQ 130 ++ CD C NGG+C+P TG C C G+ G +CQ Sbjct: 315 SQHCD--CHNGGQCSPTTGACECEPGYKGPRCQ 345 Score = 40.8 bits (94), Expect = 0.009 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 18/90 (20%) Query: 250 CPN-----NCSGRGECKISNSSDTVE--CECSENWKGEACDIP--------HCTDNCGFP 294 CP+ NC+ C + ++ C C+ W G+ C++P +C+++C Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS 539 Query: 295 HRGICNSSDVRG-CSCFSDWQGPGCSVPVP 323 H C+ V G C C + W G C P Sbjct: 540 HADGCD--PVTGHCCCLAGWTGIRCDSTCP 567 Score = 39.7 bits (91), Expect = 0.021 Identities = 19/53 (35%), Positives = 21/53 (39%), Gaps = 2/53 (3%) Query: 79 CEAEAAAAAAAVSGSAAAEAKECDR--PCVNGGRCNPGTGQCVCPAGWVGEQC 129 C AVS +A C C NGG C+P G C C GW G C Sbjct: 424 CAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC 476 Score = 38.5 bits (88), Expect = 0.047 Identities = 12/26 (46%), Positives = 16/26 (61%) Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQ 130 C NG C+P G C C GW+G+ C+ Sbjct: 495 CANGAACSPIDGSCSCTPGWLGDTCE 520 Score = 37.4 bits (85), Expect = 0.10 Identities = 12/25 (48%), Positives = 15/25 (60%) Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQC 129 C N G C+P G C C GW+G+ C Sbjct: 669 CANNGTCSPIDGSCQCFPGWIGKDC 693 Score = 36.6 bits (83), Expect = 0.18 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 19/70 (27%) Query: 79 CEAEAAAAAAAVSGSAAAE----AKECDRPCVNG---------------GRCNPGTGQCV 119 C AA + + GS + C+ PC +G C+P TG C Sbjct: 493 CTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC 552 Query: 120 CPAGWVGEQC 129 C AGW G +C Sbjct: 553 CLAGWTGIRC 562 Score = 35.8 bits (81), Expect = 0.30 Identities = 20/67 (29%), Positives = 24/67 (35%), Gaps = 11/67 (16%) Query: 271 CECSENWKGEACDI--------PHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPV 322 CEC + G C+ C C + G C+ D C CF W G CS Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPID-GSCQCFPGWIGKDCSQAC 697 Query: 323 PANQSFW 329 P FW Sbjct: 698 P--PGFW 702 Score = 35.8 bits (81), Expect = 0.30 Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 13/80 (16%) Query: 253 NCSGRGECKISNSSDTVECECSENWKGEACDI--------PHCTDNCGFPHRGICNSSDV 304 +C+ G C + S C+C W G+ C P C C H G S++ Sbjct: 668 SCANNGTCSPIDGS----CQCFPGWIGKDCSQACPPGFWGPACFHACSC-HNGASCSAED 722 Query: 305 RGCSCFSDWQGPGCSVPVPA 324 C C W G C+ PA Sbjct: 723 GACHCTPGWTGLFCTQRCPA 742 Score = 35.8 bits (81), Expect = 0.30 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%) Query: 94 AAAEAKECDR--PCVNGGRCNPGTGQCVCPAGWVGEQCQ 130 AA K+C R C NG C+ +G+C C G+ G+ C+ Sbjct: 742 AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE 780 Score = 35.4 bits (80), Expect = 0.40 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 19/81 (23%) Query: 68 LSPPLLLLLLPCEAEAAAAAAAVSGSAAAE-----------------AKECDRPCV--NG 108 L P L PC+A+ + V+G+ + C PC NG Sbjct: 353 LHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNG 412 Query: 109 GRCNPGTGQCVCPAGWVGEQC 129 C+ TG C C G++GE C Sbjct: 413 ADCHSITGGCTCAPGFMGEVC 433 Score = 35.0 bits (79), Expect = 0.52 Identities = 13/26 (50%), Positives = 15/26 (57%) Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQ 130 C NGG C+P G C C G+ G CQ Sbjct: 581 CENGGSCSPEDGSCECAPGFRGPLCQ 606 Score = 34.3 bits (77), Expect = 0.88 Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 15/82 (18%) Query: 245 YSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDI--------PHCTDNCGFPHR 296 + +C C G C S DT C C W G C PHC++ C + Sbjct: 98 FCIPLCTEECV-HGRCV---SPDT--CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNG 151 Query: 297 GICNSSDVRGCSCFSDWQGPGC 318 +CN C C + ++G C Sbjct: 152 ALCNPI-TGACVCAAGFRGWRC 172 Score = 32.3 bits (72), Expect = 3.4 Identities = 14/33 (42%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQC-QHCGGRF 136 C NG C+ G C C GW G C Q C F Sbjct: 712 CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAF 744 Score = 31.6 bits (70), Expect = 5.7 Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 6/41 (14%) Query: 279 GEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCS 319 G+ C IP CT+ C G C S D C C W GP CS Sbjct: 96 GDFC-IPLCTEECV---HGRCVSPDT--CHCEPGWGGPDCS 130 >gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens] Length = 3667 Score = 67.8 bits (164), Expect = 7e-11 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 8/114 (7%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG F PG YK C W+IE +P +++ F F TE ++D L V+DG Sbjct: 855 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 914 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 ++ +PL+ +++G VP+ + ++S + L F +D + + GF I Y Sbjct: 915 PNLLSPLLGSYNGTQVPQ--------FLFSSSNFIYLLFTTDNSRSNNGFKIHY 960 Score = 67.8 bits (164), Expect = 7e-11 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 12/116 (10%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG LTGSSGF+ P Y + C W I + ++ L F F+ E ++D LY+Y Sbjct: 1548 CGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG +PL+ +F +PER + ++S L F SD + + TGF++ Y Sbjct: 1606 DGPDSNSPLIGSFQDSKLPER--------IESSSNTMHLAFRSDGSVSYTGFHLEY 1653 Score = 60.8 bits (146), Expect = 9e-09 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 17/158 (10%) Query: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190 CGGRF+ S ++ G P Y +C W+IE P I+ L+F F TE S D L V+D Sbjct: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1433 Query: 191 GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250 G L+ SG ++PE + +T + F +D + +GF I +S + Sbjct: 1434 GPPENDMLLKEISGSLIPE--------GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485 Query: 251 --------PNNCSGRGECKISNSSDTVECECSENWKGE 280 P N + G+ + + +C+ +GE Sbjct: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1523 Score = 58.5 bits (140), Expect = 4e-08 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 15/114 (13%) Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206 D P Y C W I P + L FN F E +D L V DGDS +P++ F+G Sbjct: 696 DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAE 755 Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGEC 260 VP + + S L F +D + + GFNITY N G EC Sbjct: 756 VPS--------HLTSNSHILRLEFQADHSMSGRGFNITY-------NTFGHNEC 794 Score = 56.6 bits (135), Expect = 2e-07 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 16/139 (11%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG R GSSG ++ P Y CTW I +P + L F F E +D+L + Sbjct: 201 CGGTMR--GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDM 249 + P SG+ +P P +++ + LHF +D+ + GF+ Y Sbjct: 259 GSE----PPTIWLSGMNIP--------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSS 306 Query: 250 CPNNCSGRGECKISNSSDT 268 + + GE + N + T Sbjct: 307 TLTHTTSTGELEEHNRTTT 325 Score = 56.2 bits (134), Expect = 2e-07 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 14/152 (9%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + P Y C W I ++++ FATE +WD L YDG Sbjct: 1899 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1958 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS---FD 248 AP + ++SG +P + +TS L+F SD + + GF++ Y+ D Sbjct: 1959 GDNNAPRLGSYSGTTIPHL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2010 Query: 249 MCPNNCSGRGECKISNS---SDTVECECSENW 277 CP + KI + D V +C + + Sbjct: 2011 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGY 2042 Score = 55.1 bits (131), Expect = 5e-07 Identities = 51/187 (27%), Positives = 72/187 (38%), Gaps = 39/187 (20%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG ++ SG + PGNY CTW I + L+F +F+TE D+L V Sbjct: 2071 CGGA--MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2128 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI---TYS 246 G S + ++ SG +P + +T+ L+F SD + N GF+I Y Sbjct: 2129 SGSSETSTVIGRLSGPQIPS--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2180 Query: 247 FDMCPNNCSGRGECKISNS---SDTVECEC------------------SENWKGEACDIP 285 CP+ R I N T+ EC S NW +P Sbjct: 2181 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNH---PLP 2237 Query: 286 HCTDNCG 292 C CG Sbjct: 2238 RCEALCG 2244 Score = 47.0 bits (110), Expect = 1e-04 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 15/130 (11%) Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188 CGG L G +G + + PG Y CTW+I + +++ F FA E +D+L + Sbjct: 25 CGGT--LKGLNGTI-ESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 81 Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFD 248 YDG +G +P P V +T L SD A + GF + Y + Sbjct: 82 YDGHPHPTNFRTRLTGFHLP--------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-E 132 Query: 249 MCPNNCSGRG 258 + ++C G Sbjct: 133 LQSSSCGNPG 142 Score = 47.0 bits (110), Expect = 1e-04 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 10/110 (9%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + + P Y C WL+ P + + F TE +D + V+DG Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2302 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241 +P + FS GN + V +TS L+ F SD + +GF Sbjct: 2303 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGF 2342 Score = 45.4 bits (106), Expect = 4e-04 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYV 188 CG L G SG T P Y +C W+I N+++++ F F E +D L + Sbjct: 508 CGSN--LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 565 Query: 189 YDGDSIYAP--LVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG + P ++ +G VP+ +V+ S LH +D + GF + Y Sbjct: 566 GDGGEVGDPRTVLQVLTGSFVPDL--------IVSMSSQMWLHLQTDESVGSVGFKVNY 616 Score = 45.4 bits (106), Expect = 4e-04 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 31/184 (16%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG R G SG + P Y CTW ++ + ++ F+ F E D+L + Sbjct: 1027 CGGDVR--GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1084 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT---YS 246 + S PL A +G +P T+ + + A L F SD + + GFNIT Y+ Sbjct: 1085 ENGSFTQPL-ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138 Query: 247 FDMCPNNCSGRGECKIS---NSSDTVECECSENWKGE---------------ACDIPHCT 288 + C + + +I DT+ CS ++ E + +P C Sbjct: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198 Query: 289 DNCG 292 CG Sbjct: 1199 AECG 1202 Score = 42.4 bits (98), Expect = 0.003 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 113 PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMR 171 P Q +CPA RL + ++ G P +Y C W I + + Sbjct: 2409 PPVCQVLCPAN-----------ELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNIT 2457 Query: 172 LRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFF 231 + F TE +D L VYDG +I +P++ + SG + + + L + Sbjct: 2458 MFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSG-------DYSSAFNITSNGHEVFLQWS 2510 Query: 232 SDAAYNLTGFNITYSFDMC 250 +D N GF I Y C Sbjct: 2511 ADHGNNKKGFRIRYIAFYC 2529 Score = 31.2 bits (69), Expect = 7.5 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%) Query: 105 CVNGGRCNPGTGQCVCPAG----WVGE--QC-QHCGGRFRLTGSSGFVTDG--PGNYKYK 155 C +G R GT + +C G W +C CG T + G + P NY+ Sbjct: 1168 CSSGYRLE-GTSEIICLGGGRRVWSAPLPRCVAECGAS--ATNNEGILLSPNYPLNYENN 1224 Query: 156 TKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNET 215 +C + I+ Q + + + F D L +YDG L+ AF+G + Sbjct: 1225 HECIYSIQVQAGKGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTG-------ASMR 1276 Query: 216 VPEVVATSGYALLHFFSDAAYNLTGFNITY-SFDMCPNNCSGRG 258 + +TS L F SD GF + Y SF++ ++C G Sbjct: 1277 GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL--SHCEDPG 1318 >gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sapiens] Length = 3538 Score = 67.8 bits (164), Expect = 7e-11 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 8/114 (7%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG F PG YK C W+IE +P +++ F F TE ++D L V+DG Sbjct: 791 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 850 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 ++ +PL+ +++G VP+ + ++S + L F +D + + GF I Y Sbjct: 851 PNLLSPLLGSYNGTQVPQ--------FLFSSSNFIYLLFTTDNSRSNNGFKIHY 896 Score = 67.8 bits (164), Expect = 7e-11 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 12/116 (10%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG LTGSSGF+ P Y + C W I + ++ L F F+ E ++D LY+Y Sbjct: 1484 CGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG +PL+ +F +PER + ++S L F SD + + TGF++ Y Sbjct: 1542 DGPDSNSPLIGSFQDSKLPER--------IESSSNTMHLAFRSDGSVSYTGFHLEY 1589 Score = 60.8 bits (146), Expect = 9e-09 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 17/158 (10%) Query: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190 CGGRF+ S ++ G P Y +C W+IE P I+ L+F F TE S D L V+D Sbjct: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1369 Query: 191 GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250 G L+ SG ++PE + +T + F +D + +GF I +S + Sbjct: 1370 GPPENDMLLKEISGSLIPE--------GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1421 Query: 251 --------PNNCSGRGECKISNSSDTVECECSENWKGE 280 P N + G+ + + +C+ +GE Sbjct: 1422 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1459 Score = 58.5 bits (140), Expect = 4e-08 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 15/114 (13%) Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206 D P Y C W I P + L FN F E +D L V DGDS +P++ F+G Sbjct: 632 DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAE 691 Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGEC 260 VP + + S L F +D + + GFNITY N G EC Sbjct: 692 VPS--------HLTSNSHILRLEFQADHSMSGRGFNITY-------NTFGHNEC 730 Score = 56.2 bits (134), Expect = 2e-07 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 14/152 (9%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + P Y C W I ++++ FATE +WD L YDG Sbjct: 1835 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1894 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS---FD 248 AP + ++SG +P + +TS L+F SD + + GF++ Y+ D Sbjct: 1895 GDNNAPRLGSYSGTTIPHL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 1946 Query: 249 MCPNNCSGRGECKISNS---SDTVECECSENW 277 CP + KI + D V +C + + Sbjct: 1947 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGY 1978 Score = 55.1 bits (131), Expect = 5e-07 Identities = 51/187 (27%), Positives = 72/187 (38%), Gaps = 39/187 (20%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG ++ SG + PGNY CTW I + L+F +F+TE D+L V Sbjct: 2007 CGGA--MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2064 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI---TYS 246 G S + ++ SG +P + +T+ L+F SD + N GF+I Y Sbjct: 2065 SGSSETSTVIGRLSGPQIPS--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2116 Query: 247 FDMCPNNCSGRGECKISNS---SDTVECEC------------------SENWKGEACDIP 285 CP+ R I N T+ EC S NW +P Sbjct: 2117 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNH---PLP 2173 Query: 286 HCTDNCG 292 C CG Sbjct: 2174 RCEALCG 2180 Score = 53.1 bits (126), Expect = 2e-06 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 16/116 (13%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG R GSSG ++ P Y CTW I +P + L F F E +D+L + Sbjct: 241 CGGTMR--GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 + P SG+ +P P +++ + LHF +D+ + GF+ Y Sbjct: 299 GSE----PPTIWLSGMNIP--------PPIISNKNWLRLHFVTDSNHRYRGFSAPY 342 Score = 47.0 bits (110), Expect = 1e-04 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 15/130 (11%) Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188 CGG L G +G + + PG Y CTW+I + +++ F FA E +D+L + Sbjct: 65 CGGT--LKGLNGTI-ESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121 Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFD 248 YDG +G +P P V +T L SD A + GF + Y + Sbjct: 122 YDGHPHPTNFRTRLTGFHLP--------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-E 172 Query: 249 MCPNNCSGRG 258 + ++C G Sbjct: 173 LQSSSCGNPG 182 Score = 47.0 bits (110), Expect = 1e-04 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 10/110 (9%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + + P Y C WL+ P + + F TE +D + V+DG Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241 +P + FS GN + V +TS L+ F SD + +GF Sbjct: 2239 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGF 2278 Score = 45.4 bits (106), Expect = 4e-04 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYV 188 CG L G SG T P Y +C W+I N+++++ F F E +D L + Sbjct: 444 CGSN--LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 501 Query: 189 YDGDSIYAP--LVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG + P ++ +G VP+ +V+ S LH +D + GF + Y Sbjct: 502 GDGGEVGDPRTVLQVLTGSFVPDL--------IVSMSSQMWLHLQTDESVGSVGFKVNY 552 Score = 45.4 bits (106), Expect = 4e-04 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 31/184 (16%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG R G SG + P Y CTW ++ + ++ F+ F E D+L + Sbjct: 963 CGGDVR--GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1020 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT---YS 246 + S PL A +G +P T+ + + A L F SD + + GFNIT Y+ Sbjct: 1021 ENGSFTQPL-ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074 Query: 247 FDMCPNNCSGRGECKIS---NSSDTVECECSENWKGE---------------ACDIPHCT 288 + C + + +I DT+ CS ++ E + +P C Sbjct: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134 Query: 289 DNCG 292 CG Sbjct: 1135 AECG 1138 Score = 42.4 bits (98), Expect = 0.003 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 113 PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMR 171 P Q +CPA RL + ++ G P +Y C W I + + Sbjct: 2345 PPVCQVLCPAN-----------ELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNIT 2393 Query: 172 LRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFF 231 + F TE +D L VYDG +I +P++ + SG + + + L + Sbjct: 2394 MFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSG-------DYSSAFNITSNGHEVFLQWS 2446 Query: 232 SDAAYNLTGFNITYSFDMC 250 +D N GF I Y C Sbjct: 2447 ADHGNNKKGFRIRYIAFYC 2465 Score = 31.2 bits (69), Expect = 7.5 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%) Query: 105 CVNGGRCNPGTGQCVCPAG----WVGE--QC-QHCGGRFRLTGSSGFVTDG--PGNYKYK 155 C +G R GT + +C G W +C CG T + G + P NY+ Sbjct: 1104 CSSGYRLE-GTSEIICLGGGRRVWSAPLPRCVAECGAS--ATNNEGILLSPNYPLNYENN 1160 Query: 156 TKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNET 215 +C + I+ Q + + + F D L +YDG L+ AF+G + Sbjct: 1161 HECIYSIQVQAGKGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTG-------ASMR 1212 Query: 216 VPEVVATSGYALLHFFSDAAYNLTGFNITY-SFDMCPNNCSGRG 258 + +TS L F SD GF + Y SF++ ++C G Sbjct: 1213 GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL--SHCEDPG 1254 >gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens] Length = 3707 Score = 67.8 bits (164), Expect = 7e-11 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 8/114 (7%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG F PG YK C W+IE +P +++ F F TE ++D L V+DG Sbjct: 895 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDG 954 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 ++ +PL+ +++G VP+ + ++S + L F +D + + GF I Y Sbjct: 955 PNLLSPLLGSYNGTQVPQ--------FLFSSSNFIYLLFTTDNSRSNNGFKIHY 1000 Score = 67.8 bits (164), Expect = 7e-11 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 12/116 (10%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG LTGSSGF+ P Y + C W I + ++ L F F+ E ++D LY+Y Sbjct: 1588 CGGN--LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1645 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG +PL+ +F +PER + ++S L F SD + + TGF++ Y Sbjct: 1646 DGPDSNSPLIGSFQDSKLPER--------IESSSNTMHLAFRSDGSVSYTGFHLEY 1693 Score = 60.8 bits (146), Expect = 9e-09 Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 17/158 (10%) Query: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYD 190 CGGRF+ S ++ G P Y +C W+IE P I+ L+F F TE S D L V+D Sbjct: 1414 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1473 Query: 191 GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250 G L+ SG ++PE + +T + F +D + +GF I +S + Sbjct: 1474 GPPENDMLLKEISGSLIPE--------GIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1525 Query: 251 --------PNNCSGRGECKISNSSDTVECECSENWKGE 280 P N + G+ + + +C+ +GE Sbjct: 1526 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGE 1563 Score = 58.5 bits (140), Expect = 4e-08 Identities = 38/114 (33%), Positives = 49/114 (42%), Gaps = 15/114 (13%) Query: 147 DGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLI 206 D P Y C W I P + L FN F E +D L V DGDS +P++ F+G Sbjct: 736 DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAE 795 Query: 207 VPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGEC 260 VP + + S L F +D + + GFNITY N G EC Sbjct: 796 VPS--------HLTSNSHILRLEFQADHSMSGRGFNITY-------NTFGHNEC 834 Score = 56.6 bits (135), Expect = 2e-07 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 16/139 (11%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG R GSSG ++ P Y CTW I +P + L F F E +D+L + Sbjct: 241 CGGTMR--GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDM 249 + P SG+ +P P +++ + LHF +D+ + GF+ Y Sbjct: 299 GSE----PPTIWLSGMNIP--------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSS 346 Query: 250 CPNNCSGRGECKISNSSDT 268 + + GE + N + T Sbjct: 347 TLTHTTSTGELEEHNRTTT 365 Score = 56.2 bits (134), Expect = 2e-07 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 14/152 (9%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + P Y C W I ++++ FATE +WD L YDG Sbjct: 1939 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDG 1998 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYS---FD 248 AP + ++SG +P + +TS L+F SD + + GF++ Y+ D Sbjct: 1999 GDNNAPRLGSYSGTTIPHL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD 2050 Query: 249 MCPNNCSGRGECKISNS---SDTVECECSENW 277 CP + KI + D V +C + + Sbjct: 2051 SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGY 2082 Score = 55.1 bits (131), Expect = 5e-07 Identities = 51/187 (27%), Positives = 72/187 (38%), Gaps = 39/187 (20%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG ++ SG + PGNY CTW I + L+F +F+TE D+L V Sbjct: 2111 CGGA--MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVR 2168 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNI---TYS 246 G S + ++ SG +P + +T+ L+F SD + N GF+I Y Sbjct: 2169 SGSSETSTVIGRLSGPQIPS--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQ 2220 Query: 247 FDMCPNNCSGRGECKISNS---SDTVECEC------------------SENWKGEACDIP 285 CP+ R I N T+ EC S NW +P Sbjct: 2221 LQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNH---PLP 2277 Query: 286 HCTDNCG 292 C CG Sbjct: 2278 RCEALCG 2284 Score = 47.0 bits (110), Expect = 1e-04 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 15/130 (11%) Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYV 188 CGG L G +G + + PG Y CTW+I + +++ F FA E +D+L + Sbjct: 65 CGGT--LKGLNGTI-ESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSL 121 Query: 189 YDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFD 248 YDG +G +P P V +T L SD A + GF + Y + Sbjct: 122 YDGHPHPTNFRTRLTGFHLP--------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYE-E 172 Query: 249 MCPNNCSGRG 258 + ++C G Sbjct: 173 LQSSSCGNPG 182 Score = 47.0 bits (110), Expect = 1e-04 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 10/110 (9%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG + + P Y C WL+ P + + F TE +D + V+DG Sbjct: 2283 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2342 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241 +P + FS GN + V +TS L+ F SD + +GF Sbjct: 2343 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGF 2382 Score = 45.4 bits (106), Expect = 4e-04 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYV 188 CG L G SG T P Y +C W+I N+++++ F F E +D L + Sbjct: 548 CGSN--LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 605 Query: 189 YDGDSIYAP--LVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DG + P ++ +G VP+ +V+ S LH +D + GF + Y Sbjct: 606 GDGGEVGDPRTVLQVLTGSFVPDL--------IVSMSSQMWLHLQTDESVGSVGFKVNY 656 Score = 45.4 bits (106), Expect = 4e-04 Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 31/184 (16%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVY 189 CGG R G SG + P Y CTW ++ + ++ F+ F E D+L + Sbjct: 1067 CGGDVR--GPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLIT 1124 Query: 190 DGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT---YS 246 + S PL A +G +P T+ + + A L F SD + + GFNIT Y+ Sbjct: 1125 ENGSFTQPL-ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1178 Query: 247 FDMCPNNCSGRGECKIS---NSSDTVECECSENWKGE---------------ACDIPHCT 288 + C + + +I DT+ CS ++ E + +P C Sbjct: 1179 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1238 Query: 289 DNCG 292 CG Sbjct: 1239 AECG 1242 Score = 42.4 bits (98), Expect = 0.003 Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 113 PGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMR 171 P Q +CPA RL + ++ G P +Y C W I + + Sbjct: 2449 PPVCQVLCPAN-----------ELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNIT 2497 Query: 172 LRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFF 231 + F TE +D L VYDG +I +P++ + SG + + + L + Sbjct: 2498 MFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSG-------DYSSAFNITSNGHEVFLQWS 2550 Query: 232 SDAAYNLTGFNITYSFDMC 250 +D N GF I Y C Sbjct: 2551 ADHGNNKKGFRIRYIAFYC 2569 Score = 31.2 bits (69), Expect = 7.5 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%) Query: 105 CVNGGRCNPGTGQCVCPAG----WVGE--QC-QHCGGRFRLTGSSGFVTDG--PGNYKYK 155 C +G R GT + +C G W +C CG T + G + P NY+ Sbjct: 1208 CSSGYRLE-GTSEIICLGGGRRVWSAPLPRCVAECGAS--ATNNEGILLSPNYPLNYENN 1264 Query: 156 TKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNET 215 +C + I+ Q + + + F D L +YDG L+ AF+G + Sbjct: 1265 HECIYSIQVQAGKGINISARTFHL-AQGDVLKIYDGKDKTTHLLGAFTG-------ASMR 1316 Query: 216 VPEVVATSGYALLHFFSDAAYNLTGFNITY-SFDMCPNNCSGRG 258 + +TS L F SD GF + Y SF++ ++C G Sbjct: 1317 GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL--SHCEDPG 1358 >gi|16945972 kelch domain containing 3 [Homo sapiens] Length = 382 Score = 67.8 bits (164), Expect = 7e-11 Identities = 58/262 (22%), Positives = 108/262 (41%), Gaps = 22/262 (8%) Query: 384 RSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYA 443 R VN+ V GH ++Y +GG T HI N + T + A Sbjct: 13 RRVNHAAVAVGH-------RVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSA 65 Query: 444 VVGHSAHIVTLKNGRVVMLVIF------GHCPLYGYISNVQEYDLDKNTWSILHTQGALV 497 + G + + ++ G +L+ G G + + +D++ + W G + Sbjct: 66 IRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVP 125 Query: 498 QGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTIL---KDSRFFR 554 GHS+ + +Y+ GGY+ A+ + ++D+++ D T WT++ +R Sbjct: 126 GARDGHSACV--LGKIMYIFGGYEQ-QADCF--SNDIHKLDTSTMTWTLICTKGSPARWR 180 Query: 555 YLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNR 614 H+A ++ M VFGG + + + +D + W P + + R Sbjct: 181 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRR 240 Query: 615 FGHSAVLHNSTMYVFGGFNSLL 636 HSA +N +Y+FGG+N+ L Sbjct: 241 -SHSAFGYNGELYIFGGYNARL 261 Score = 62.0 bits (149), Expect = 4e-09 Identities = 61/253 (24%), Positives = 108/253 (42%), Gaps = 32/253 (12%) Query: 341 RASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDL-----ASREWL---PLNRSVNNVV-- 390 R +H AV G+ ++ GGY + DY + D+ S W P+ ++ Sbjct: 14 RVNHAAVAVGHRVYSFGGYC-SGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAPV 72 Query: 391 ---VRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGH 447 +RYGHS L D + ++GG+ D+ G N L F ++ W A GH Sbjct: 73 VPYMRYGHSTVLIDDTVLLWGGRNDTEG-ACNVLYAFDVNTHKWFTPRVSGTVPGARDGH 131 Query: 448 SAHIVTLKNGRVVMLVIFGHCPLYG--YISNVQEYDLDKNTWSILHTQGALVQGGYGHSS 505 SA ++ G++ + IFG + +++ + D TW+++ T+G+ + HS+ Sbjct: 132 SACVL----GKI--MYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSA 185 Query: 506 VYDHRTRALYVHGG----YKAFSANKYRLADDLYRYDVDTQMWTILKDSRFF---RYLHT 558 +YV GG + F +N + + +D T+ W + R H+ Sbjct: 186 TM--LGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHS 243 Query: 559 AVIVSGTMLVFGG 571 A +G + +FGG Sbjct: 244 AFGYNGELYIFGG 256 Score = 47.0 bits (110), Expect = 1e-04 Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 21/244 (8%) Query: 341 RASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALY 400 R H V+ + + + GG N++ A+D+ + +W S R GHS + Sbjct: 77 RYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVL 136 Query: 401 KDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVV 460 +Y++GG +N++ +W L+ K HSA ++ Sbjct: 137 GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSH----- 191 Query: 461 MLVIFGHCPLYG--------YISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTR 512 M V G +G Y + ++ +D W L +G HS+ Sbjct: 192 MYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAF--GYNG 249 Query: 513 ALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILK---DSRFFRYLHTAVIVSGTMLVF 569 LY+ GGY +A R DL++++ + W ++ R IV +++F Sbjct: 250 ELYIFGGY---NARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLF 306 Query: 570 GGNT 573 GG + Sbjct: 307 GGTS 310 >gi|164414431 netrin G1 isoform 1 [Homo sapiens] Length = 539 Score = 66.6 bits (161), Expect = 2e-10 Identities = 53/201 (26%), Positives = 79/201 (39%), Gaps = 34/201 (16%) Query: 971 GQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQ 1030 G+C + C +N C C H P CG C + +Y+G P Sbjct: 295 GRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKC------------KKNYQGRPWSP-- 340 Query: 1031 APTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHS-KC-----INQSICEKCENLT 1084 G++ P P ++ C+ S C+C GHS +C +N IC C++ T Sbjct: 341 ---GSYLPIPKGTANTCIP------SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNT 391 Query: 1085 TGKHCETCISGFYGDPT----NGGKCQPCKCNGHASLCNTNTGKCFCTTK-GVKGDECQL 1139 G+HCE C G++ + + + C C CN S+ + G FC K G G +C Sbjct: 392 RGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDE 451 Query: 1140 CEVENRYQGNPLRGTCYYTLL 1160 C N + C LL Sbjct: 452 CLPGNSWHYGCQPNVCDNELL 472 >gi|110611156 laminin, gamma 3 precursor [Homo sapiens] Length = 1575 Score = 66.6 bits (161), Expect = 2e-10 Identities = 58/205 (28%), Positives = 74/205 (36%), Gaps = 62/205 (30%) Query: 981 TCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQP 1040 TC P +G C CSH E P C +C+ G Y P QA P P Sbjct: 714 TCDPN--TGICVCSHHTEGPSCE-----------RCLPGFYGNP--FAGQADDCQPCPCP 758 Query: 1041 LLNSSMCLEDSRYNWSFIHCPA------------------------------CQCNGH-- 1068 ++ + +SR HCP CQC+G+ Sbjct: 759 GQSACTTIPESR-EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVD 817 Query: 1069 ----SKCINQS-ICEKCENLTTGKHCETCISGFYGD---PTNGGKCQPCKCNGHASL--- 1117 C S C +C + TTG HCE C GFYG P KC PC C+ S+ Sbjct: 818 PNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQ 877 Query: 1118 --CNTNTGKCFCTTKGVKGDECQLC 1140 C+ TG+C C V +C C Sbjct: 878 MPCDPVTGQCSCLPH-VTARDCSRC 901 Score = 65.9 bits (159), Expect = 3e-10 Identities = 39/102 (38%), Positives = 52/102 (50%), Gaps = 11/102 (10%) Query: 1057 FIHCPACQCNGHSKCI-NQSICEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNG 1113 + C C CN H C N IC C + T G CE C+ GFYG+P G CQPC C G Sbjct: 701 YASCVPCTCNQHGTCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759 Query: 1114 HASLCNT--NTGKCFCT--TKGVKGDECQLCEVENRYQGNPL 1151 S C T + + CT G +G C++C ++ + G+PL Sbjct: 760 Q-SACTTIPESREVVCTHCPPGQRGRRCEVC--DDGFFGDPL 798 Score = 57.0 bits (136), Expect = 1e-07 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 11/99 (11%) Query: 1049 EDSRYNWS-FIHCPACQCNG----HSKCINQSICEKCENLTTGKHCETCISGFYGDPTNG 1103 +++ Y+W + C C C H +C + C C+ TG C+ C+ GF+ + Sbjct: 368 QENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCA-CKPTVTGWKCDRCLPGFHS--LSE 424 Query: 1104 GKCQPCKCNGHASL--CNTNTGKCFCTTKGVKGDECQLC 1140 G C+PC CN SL C+ +G+C C + V+G+ C C Sbjct: 425 GGCRPCTCNPAGSLDTCDPRSGRCPC-KENVEGNLCDRC 462 Score = 53.5 bits (127), Expect = 1e-06 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 22/108 (20%) Query: 1063 CQCNGH-SKC----INQSICEKCENLTTGKHCETCISGFYGDPTNGG------KCQPCKC 1111 C+CNGH S+C Q C +C++ TTG CE C+ F P G +C PC C Sbjct: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329 Query: 1112 NGHASLCNTNT---------GKCFCTTKGVKGDECQLCEVENRYQGNP 1150 +G + C + G+C G C+ C+ EN Y +P Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQ-ENFYHWDP 376 Score = 50.4 bits (119), Expect = 1e-05 Identities = 35/95 (36%), Positives = 41/95 (43%), Gaps = 20/95 (21%) Query: 1060 CPACQCNGHSK-CI----------NQSICEKCENLTTGKHCETCISGFY-GDPTNGGKCQ 1107 C C C+G S+ C + C C + T G HCE C FY DP CQ Sbjct: 324 CLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM--PCQ 381 Query: 1108 PCKCNGHASL---CNTNTGKCFC--TTKGVKGDEC 1137 PC C SL C+ +TG C C T G K D C Sbjct: 382 PCDCQSAGSLHLQCD-DTGTCACKPTVTGWKCDRC 415 Score = 42.0 bits (97), Expect = 0.004 Identities = 51/189 (26%), Positives = 74/189 (39%), Gaps = 39/189 (20%) Query: 979 MSTCPPENCSGYCT----------CSHCLEQ-PGCGWCTDPSNTGKGKCIEGSY--KGPV 1025 + C P SG+C C HC E G P++ KC+ S +G V Sbjct: 821 VGNCDP--LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPAD----KCMPCSCHPQGSV 874 Query: 1026 --KMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIH------CPACQCNG----HSKCIN 1073 +MP TG P + + C SR F C +C+C+ +C Sbjct: 875 SEQMPCDPVTGQCSCLPHVTARDC---SRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHP 931 Query: 1074 QSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCN--GHASLCNTNTGKCFCTTKG 1131 ++ C TG+ C+ C GF+G G C+ C+C+ G AS G C C G Sbjct: 932 KTGQCTCRPGVTGQACDRCQLGFFGFSIKG--CRACRCSPLGAASAQCHENGTCVC-RPG 988 Query: 1132 VKGDECQLC 1140 +G +C C Sbjct: 989 FEGYKCDRC 997 Score = 39.7 bits (91), Expect = 0.021 Identities = 52/222 (23%), Positives = 69/222 (31%), Gaps = 54/222 (24%) Query: 939 CGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMST-----CPPENCSGY--- 990 CG +G C C + D + PF Q W + C P NCSG Sbjct: 280 CGPDVAGQLACR-CQHNTTGTDCERCL---PFFQDRPWARGTAEAAHECLPCNCSGRSEE 335 Query: 991 CT--------------CSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQA----- 1031 CT C HC + C +C E Y +MP Q Sbjct: 336 CTFDRELFRSTGHGGRCHHCRDHTAGPHCE--------RCQENFYHWDPRMPCQPCDCQS 387 Query: 1032 ---------PTGNFYPQPLLNSSMCLE--DSRYNWSFIHCPACQCNGHSK---CINQSIC 1077 TG +P + C ++ S C C CN C +S Sbjct: 388 AGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR 447 Query: 1078 EKCENLTTGKHCETCISGFYG-DPTNGGKCQPCKCNGHASLC 1118 C+ G C+ C G + P N C C C GH+ +C Sbjct: 448 CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVC 489 Score = 35.4 bits (80), Expect = 0.40 Identities = 31/112 (27%), Positives = 40/112 (35%), Gaps = 16/112 (14%) Query: 637 LSDILVFTSEQCDAHRSEAACLAAGP-GIRCVWNTGSSQCIS---------WALATDEQ- 685 +SD V +C+ H SE AG RC NT + C WA T E Sbjct: 262 VSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAA 321 Query: 686 EEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCV-PRNHSCSE 736 E L C + + C + + T + CH C DH P C E Sbjct: 322 HECLPCNCSGRS----EECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE 369 Score = 33.5 bits (75), Expect = 1.5 Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 110 RCNPGTGQCVCPAGWVGEQCQHC 132 +C+P TGQC C G G+ C C Sbjct: 928 QCHPKTGQCTCRPGVTGQACDRC 950 Score = 32.3 bits (72), Expect = 3.4 Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 105 CVNGGRCNPGTGQCVCPAGWVGEQCQHC 132 C G C+P TG CVC G C+ C Sbjct: 709 CNQHGTCDPNTGICVCSHHTEGPSCERC 736 >gi|126091152 cubilin [Homo sapiens] Length = 3623 Score = 66.2 bits (160), Expect = 2e-10 Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 21/158 (13%) Query: 100 EC-DRPCVNGGRCNPGTGQ--CVCPAGWVGEQCQH----CGGRFR-LTGSSGFVTDGPGN 151 EC PC+NGG C G C C W G CQ CG + GS + + G Sbjct: 435 ECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFSYRSPDVG- 493 Query: 152 YKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFSGLIV 207 Y + C W+I+ + +++R+ F F E C + L VYDGDS A + F G + Sbjct: 494 YVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSL 553 Query: 208 PERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 P E++++ H +S+ N GF + + Sbjct: 554 PH--------ELLSSDNALYFHLYSEHLRNGRGFTVRW 583 Score = 65.5 bits (158), Expect = 4e-10 Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 23/138 (16%) Query: 130 QHCGGRFRLTGSSGFV----TDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----- 180 Q CGG LTGS+ +D G Y C W+I N+++ L FN FA E Sbjct: 3155 QGCGGY--LTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTR 3212 Query: 181 --CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNL 238 C +D++ +YDGDS A L F G VP +++ + + F SD Sbjct: 3213 QRCLYDYVKLYDGDSENANLAGTFCGSTVP--------APFISSGNFLTVQFISDLTLER 3264 Query: 239 TGFNITYSFDMCPNNCSG 256 GFN TY+ P C G Sbjct: 3265 EGFNATYTIMDMP--CGG 3280 Score = 57.4 bits (137), Expect = 1e-07 Identities = 40/135 (29%), Positives = 58/135 (42%), Gaps = 16/135 (11%) Query: 128 QCQHCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----C 181 Q CGG LTG G + PGNY C W++ P+ ++ F + E C Sbjct: 586 QQPECGGI--LTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDC 643 Query: 182 SWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241 + D+L + DG PL+ F +VP + T +A +HF SD+ + GF Sbjct: 644 NKDYLEIRDGPLYQDPLLGKFCTTF--------SVPPLQTTGPFARIHFHSDSQISDQGF 695 Query: 242 NITYSFDMCPNNCSG 256 +ITY C G Sbjct: 696 HITYLTSPSDLRCGG 710 Score = 51.2 bits (121), Expect = 7e-06 Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 18/123 (14%) Query: 130 QHCGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQP--NRIMRLRFNHF----ATEC 181 Q CGG LT S V+ P NY C+W+I+ QP N I L F HF +T C Sbjct: 1618 QACGGHI-LTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHI-TLSFTHFELERSTTC 1675 Query: 182 SWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGF 241 + D + + DG APL + G +P + + S L F SD++ + GF Sbjct: 1676 ARDFVEILDGGHEDAPLRGRYCGTDMPH--------PITSFSSALTLRFVSDSSISAGGF 1727 Query: 242 NIT 244 + T Sbjct: 1728 HTT 1730 Score = 49.7 bits (117), Expect = 2e-05 Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 18/133 (13%) Query: 132 CGGRFRLTGSSGFVTDGP---GNYKYKTKCTWLIEGQPNRIMRLRFNHF----ATECSWD 184 CGG F SSG +T +Y C + I ++++ L+F+ F +T CS D Sbjct: 3037 CGGVFNF--SSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHD 3094 Query: 185 HLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT 244 +L +YDG + PL+ F G++ P V +++ LL F +D+ G+ ++ Sbjct: 3095 YLAIYDGANTSDPLLGKFC--------GSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3146 Query: 245 YSFDMCP-NNCSG 256 + + P C G Sbjct: 3147 FRQTLGPQQGCGG 3159 Score = 48.5 bits (114), Expect = 5e-05 Identities = 35/121 (28%), Positives = 54/121 (44%), Gaps = 17/121 (14%) Query: 132 CGGRFRLTGSSGFVTDGPG---NYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWD 184 CGG R TG + PG +Y + CTWLI+ P+ + L E C++D Sbjct: 1978 CGGFLR-TGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYD 2035 Query: 185 HLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNIT 244 L + DGD+ A +A G +P + +T Y + F SD++ GFN + Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIP--------GPIRSTGEYMFIRFTSDSSVTRAGFNAS 2087 Query: 245 Y 245 + Sbjct: 2088 F 2088 Score = 48.1 bits (113), Expect = 6e-05 Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 17/132 (12%) Query: 132 CGGRFRLTGSSG-FVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDH 185 CGG L+G++G F + G P Y +C W I P ++L + F E C++D Sbjct: 1391 CGGE--LSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDV 1448 Query: 186 LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNIT 244 L +Y G ++P +A PE P V+++G L + F +D + N GFN Sbjct: 1449 LEIYGGPDFHSPRIAQLCTQRSPEN------PMQVSSTGNELAIRFKTDLSINGRGFNA- 1501 Query: 245 YSFDMCPNNCSG 256 S+ C G Sbjct: 1502 -SWQAVTGGCGG 1512 Score = 47.0 bits (110), Expect = 1e-04 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 15/120 (12%) Query: 132 CGGRFRLTGSSG-FVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFAT----ECSWDH 185 CGG L G G F + G PG Y T C W++ R++ + F + +C ++ Sbjct: 3511 CGGT--LYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNY 3568 Query: 186 LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 L +YDG + +P + G G+ ++ VA+S + F +D A + F +T+ Sbjct: 3569 LTLYDGPNASSPSSGPYCG-------GDTSIAPFVASSNQVFIKFHADYARRPSAFRLTW 3621 Score = 46.2 bits (108), Expect = 2e-04 Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 16/114 (14%) Query: 138 LTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDG 191 LT S+G + P Y + CTW I QPN ++ L F F E C+ D+L VYD Sbjct: 936 LTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDT 995 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 DS + + G +P P + ++ +L F +D+ GF I Y Sbjct: 996 DS--ETSLGRYCGKSIP--------PSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039 Score = 46.2 bits (108), Expect = 2e-04 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 19/136 (13%) Query: 132 CGGRFRL--TGSSGFVT--DGPGNYKYKTKCTWLIEGQPNRIMRLRFN-----HFATECS 182 CGG + S+G+VT + P NY C W++ P ++L+F C+ Sbjct: 2217 CGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCT 2276 Query: 183 WDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGF 241 ++L + DG AP+++ F G +P +SG + L F SD + GF Sbjct: 2277 SNYLELRDGVDSDAPILSKFCGTSLPSSQW---------SSGEVMYLRFRSDNSPTHVGF 2327 Query: 242 NITYSFDMCPNNCSGR 257 YS C G+ Sbjct: 2328 KAKYSIAQCGGRVPGQ 2343 Score = 44.7 bits (104), Expect = 7e-04 Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 36/180 (20%) Query: 96 AEAKECDRPCVNGGRCNPGTGQCVCPA---------------GWVGEQCQHCGGRFRLTG 140 A +E D+ + G N G + P+ G+ CG F TG Sbjct: 2869 AGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQGFSASFVSRCGSNF--TG 2926 Query: 141 SSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE--------CSWDHLYVYD 190 SG++ P Y CT++IE P ++ L F F E C D +++ Sbjct: 2927 PSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIR 2986 Query: 191 GDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMC 250 G S+ + A G + +P + +G LL+F+S+ GF +Y C Sbjct: 2987 GYSVMSTPFATVCG---------DEMPAPLTIAGPVLLNFYSNEQITDFGFKFSYRIISC 3037 Score = 42.0 bits (97), Expect = 0.004 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 10/112 (8%) Query: 216 VPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNN-CSGRGECKISNSSDTVECECS 274 +P+ +++ Y L D G T +C +N C G C N D+ C C Sbjct: 102 LPQNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCL--NLHDSFFCICP 159 Query: 275 ENWKGEAC--DIPHCTDNCGFP----HRGIC-NSSDVRGCSCFSDWQGPGCS 319 WKG C D+ C G P + G C N+ C C + GP C+ Sbjct: 160 PQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCA 211 Score = 41.6 bits (96), Expect = 0.006 Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 16/121 (13%) Query: 132 CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDH 185 CGG G SG +T P Y T C+ L+E + L F+ F E C+WD Sbjct: 2689 CGGI--QIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDS 2746 Query: 186 LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245 + V +G S +P++ + GN + + S ++ F SD + GF T+ Sbjct: 2747 VTVRNGGSPESPIIGQYC--------GNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATW 2798 Query: 246 S 246 + Sbjct: 2799 N 2799 Score = 40.0 bits (92), Expect = 0.016 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 18/121 (14%) Query: 132 CGGRFRLTGSSG-FVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDH 185 CGG LT SSG F++ P Y + ++C W ++ L F F E C+ D+ Sbjct: 1165 CGGN--LTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDY 1222 Query: 186 LYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNIT 244 L VYDG S + L+ G + P ++ +SG ++ + +D GF Sbjct: 1223 LAVYDGPSSNSHLLTQLCG---------DEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAE 1273 Query: 245 Y 245 Y Sbjct: 1274 Y 1274 Score = 40.0 bits (92), Expect = 0.016 Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 17/138 (12%) Query: 122 AGWVGEQCQHCGGRFRLTGSSGFVT---DGPGNYKYKTKCTWLIEG--QPNRIMRLRFNH 176 A + + CGG T F + DG NY C W + Q N + + F Sbjct: 2560 ASYTSSEDAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFED 2619 Query: 177 FATE----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFS 232 F E C +D L GD+ PL+ G P T+P V+ S +HF + Sbjct: 2620 FYLESHQDCQFDVLEFRVGDAD-GPLMWRLCGPSKP------TLPLVIPYS-QVWIHFVT 2671 Query: 233 DAAYNLTGFNITYSFDMC 250 + GF+ YSF C Sbjct: 2672 NERVEHIGFHAKYSFTDC 2689 Score = 39.3 bits (90), Expect = 0.027 Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Query: 132 CGGRFRLTGSSGFVTD-GPGNYKYKTK--CTWLIEGQPNRIMRLRFNHF----ATECSWD 184 CGGR + G SG V G Y+ C W ++G + + F F ++ C D Sbjct: 2336 CGGR--VPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKD 2393 Query: 185 HLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGY-ALLHFFSDAAYNLTGFNI 243 + ++D + SG I+ GN T+P+ + TS A++ F +D + +GF + Sbjct: 2394 FVEIWDNHT---------SGNILGRYCGN-TIPDSIDTSSNTAVVRFVTDGSVTASGFRL 2443 Query: 244 TYSFDMCPNNCSG 256 + M C G Sbjct: 2444 RFESSM--EECGG 2454 Score = 38.1 bits (87), Expect = 0.061 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 5/77 (6%) Query: 230 FFSDAAYNLTGFNITYSFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEACDIPHCT 288 +F TG N T + + C +N C G C + D+ CEC+ W G C +P Sbjct: 416 YFCKCDSGWTGVNCTENINECLSNPCLNGGTCV--DGVDSFSCECTRLWTGALCQVPQ-- 471 Query: 289 DNCGFPHRGICNSSDVR 305 CG GI S R Sbjct: 472 QVCGESLSGINGSFSYR 488 Score = 37.7 bits (86), Expect = 0.080 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 14/112 (12%) Query: 149 PGNYKYKTKCTWLIEGQPNRIMRLRFNHF----ATECSWDHLYVYDGDSIYAPLVAAFSG 204 P NY CT + N + L F+ + EC D L V +G + +PL+ + G Sbjct: 3412 PDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCG 3471 Query: 205 LIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSG 256 ++P V + + L F SD+ + G+ I ++ P+ C G Sbjct: 3472 TLLPN--------PVFSQNNELYLRFKSDSVTSDRGYEIIWT--SSPSGCGG 3513 Score = 37.0 bits (84), Expect = 0.14 Identities = 24/131 (18%), Positives = 53/131 (40%), Gaps = 17/131 (12%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATEC----SWDHLY 187 CGG + F+ + G + + +C ++++ +++ F H +C S +++ Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767 Query: 188 VYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSF 247 V DG+++ + GN T+ + + + + F DA+ F Y Sbjct: 768 VRDGETLLGKVC------------GNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 815 Query: 248 DMCPNNCSGRG 258 C + +G G Sbjct: 816 -ACGDELTGEG 825 Score = 36.6 bits (83), Expect = 0.18 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 9/115 (7%) Query: 132 CGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDG 191 CGG F+ + P Y+ T C+W+I N + L F F E + YDG Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMAYDG 1569 Query: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYAL-LHFFSDAAYNLTGFNITY 245 L + S L G E + + +SG +L L F S + GF + Sbjct: 1570 ------LSSTMSRL--ARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616 Score = 32.3 bits (72), Expect = 3.4 Identities = 20/67 (29%), Positives = 23/67 (34%), Gaps = 5/67 (7%) Query: 260 CKISNSSDTVE---CECSENWKGEAC--DIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQ 314 C DTV C+C W G C +I C N + D C C W Sbjct: 404 CLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWT 463 Query: 315 GPGCSVP 321 G C VP Sbjct: 464 GALCQVP 470 >gi|50659100 regeneration associated muscle protease isoform b [Homo sapiens] Length = 720 Score = 66.2 bits (160), Expect = 2e-10 Identities = 47/181 (25%), Positives = 74/181 (40%), Gaps = 19/181 (10%) Query: 120 CPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFAT 179 C AGW G C CG R + +Y C W I +P +++LRF + Sbjct: 116 CRAGWYGGDCMRCGQVLRAPKGQILLE----SYPLNAHCEWTIHAKPGFVIQLRFVMLSL 171 Query: 180 E----CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAA 235 E C +D++ V DGD+ G I+ GNE + + + F SD + Sbjct: 172 EFDYMCQYDYVEVRDGDN--------RDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGS 223 Query: 236 YNLTGFNITY-SFDMCPNN-CSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGF 293 N GF+ Y C ++ C G C + + + + +C C + G+ C+ NC Sbjct: 224 KNFDGFHAIYEEITACSSSPCFHDGTC-VLDKAGSYKCACLAGYTGQRCENLLEERNCSD 282 Query: 294 P 294 P Sbjct: 283 P 283 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 65.1 bits (157), Expect = 5e-10 Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 9/88 (10%) Query: 1059 HCPACQCNGHSKCINQSI--CEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGH 1114 HC C+CNGHS + C +C++ G+ CE C G+YGD T G CQPC C Sbjct: 1559 HCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC--- 1615 Query: 1115 ASLCN-TNTGKCFCTTKGVKGDECQLCE 1141 L N N C + G G C CE Sbjct: 1616 -PLTNPENMFSRTCESLGAGGYRCTACE 1642 Score = 59.7 bits (143), Expect = 2e-08 Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 15/107 (14%) Query: 1060 CPACQCNGHSKCINQSI--CEKCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGH- 1114 C C C+GHS+ C+ C++ T G CE C G+YGD G CQ C C G Sbjct: 1156 CERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDP 1215 Query: 1115 -----ASLCNTNTG---KCFCTTKGVKGDECQLCEVENRYQGNPLRG 1153 A C +T C + G G C+ C Y GNP +G Sbjct: 1216 AAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERC--APGYYGNPSQG 1260 Score = 50.8 bits (120), Expect = 9e-06 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 1079 KCENLTTGKHCETCISGFY--GDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDE 1136 +C G C+ C G+ G G C+ C+CNGH+ LC+ TG C G+ Sbjct: 1531 RCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEF 1590 Query: 1137 CQLCEVENRYQGNPLRGT 1154 C+LC Y G+ GT Sbjct: 1591 CELC--APGYYGDATAGT 1606 Score = 50.1 bits (118), Expect = 2e-05 Identities = 58/227 (25%), Positives = 89/227 (39%), Gaps = 56/227 (24%) Query: 924 HSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCP 983 HS ++CR P SG S C +A+ P G + TC Sbjct: 726 HSVEECRCPIGY--------SGLS----------CESCDAHFTRVPGGPYL-----GTCS 762 Query: 984 PENCSGYCTCSHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFYPQ 1039 NC+G+ S C P G C + + +G KC G + +K + A + P Sbjct: 763 GCNCNGHA--SSC--DPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMK--ATATSCRPCPC 816 Query: 1040 PLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGD 1099 P +++S D+ + +G Q+ C+ C TG+ CE+C G+ G+ Sbjct: 817 PYIDASRRFSDTCF---------LDTDG------QATCDACAPGYTGRRCESCAPGYEGN 861 Query: 1100 PTN-GGKCQP-----CKCNGHASLCNTNTGKCFCTTKGVKGDECQLC 1140 P GGKC+P +C+ S+ T+ C C V G C C Sbjct: 862 PIQPGGKCRPVNQEIVRCDERGSM-GTSGEACRC-KNNVVGRLCNEC 906 Score = 49.3 bits (116), Expect = 3e-05 Identities = 56/230 (24%), Positives = 76/230 (33%), Gaps = 62/230 (26%) Query: 927 KQCRTPCALR-TACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPE 985 +QC P R +C DC +G + S Y+ + +C C PE Sbjct: 1124 EQCSCPPGYRGPSCQDCDTGYTR----------TPSGLYLGTCE--RCSCHGHSEACEPE 1171 Query: 986 N--CSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKM--PSQAPTGNFYPQPL 1041 C G C H E P C C + Y G + P Y P Sbjct: 1172 TGACQG---CQHHTEGPRCEQC------------QPGYYGDAQRGTPQDCQLCPCYGDPA 1216 Query: 1042 LNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPT 1101 + H +GH C + C +G+HCE C G+YG+P+ Sbjct: 1217 AGQAA------------HTCFLDTDGHPTC------DACSPGHSGRHCERCAPGYYGNPS 1258 Query: 1102 NGGKCQ-------PCKCN----GHASLCNTNTGKCFCTTKGVKGDECQLC 1140 G CQ P CN G S G+C C + V+G C C Sbjct: 1259 QGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQ-VEGLTCSHC 1307 Score = 48.5 bits (114), Expect = 5e-05 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 1086 GKHCETCISGFYGDPTNG--GKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVE 1143 G C+ C +G+ P+ G C+ C C+GH+ C TG C +G C+ C + Sbjct: 1134 GPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQC--Q 1191 Query: 1144 NRYQGNPLRGT 1154 Y G+ RGT Sbjct: 1192 PGYYGDAQRGT 1202 Score = 45.8 bits (107), Expect = 3e-04 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 1079 KCENLTTGKHCETCISGFYGDPTNG--GKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDE 1136 +C +G CE+C + F P G C C CNGHAS C+ G C +G + Sbjct: 732 RCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQ 791 Query: 1137 CQLCE 1141 C C+ Sbjct: 792 CNKCK 796 Score = 44.7 bits (104), Expect = 7e-04 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 3/33 (9%) Query: 102 DRPCVNGGRCNPGTGQ---CVCPAGWVGEQCQH 131 DRPC NGG+C+ CVCPAG+ G +C+H Sbjct: 3850 DRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEH 3882 Score = 37.4 bits (85), Expect = 0.10 Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 10/55 (18%) Query: 104 PCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGR------FRLTGSSGFVTDGPGNY 152 PC++GG C GT +C+C G+ G +CQ G + L GS G D PG Y Sbjct: 4152 PCLHGGTCQ-GT-RCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGG--NDAPGQY 4202 Score = 36.2 bits (82), Expect = 0.23 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Query: 1077 CEKCENLTTGKHCETCISGFYGDPT-NGGKCQP 1108 C CE TG++CE C G+ G+P+ GG+C P Sbjct: 1638 CTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670 Score = 34.3 bits (77), Expect = 0.88 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Query: 237 NLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACD---IPHCTDNCGF 293 NLT I++ C G+C S SS V C C + G C+ HC Sbjct: 3836 NLTAHGISHCPTCRDRPCQNGGQCHDSESSSYV-CVCPAGFTGSRCEHSQALHCHPEACG 3894 Query: 294 PHRGICNSSDVRGCSC 309 P N D RG +C Sbjct: 3895 PDATCVNRPDGRGYTC 3910 Score = 33.1 bits (74), Expect = 2.0 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 55 PPLRPRLLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPG 114 P R LL+ L L L+ A ++ ++ S +A + E +P + Sbjct: 1475 PATREHLLMALADLDELLI--------RATFSSVPLAASISAVSLEVAQPGPSNRPRALE 1526 Query: 115 TGQCVCPAGWVGEQCQHCGGRFRLTGS 141 +C CP G++G CQ C + TGS Sbjct: 1527 VEECRCPPGYIGLSCQDCAPGYTRTGS 1553 Score = 32.3 bits (72), Expect = 3.4 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%) Query: 97 EAKECDR-PCVNGGRCNPGTG---QCVCPAGWVGEQCQH 131 ++ C+R PC +G C P QC+C G+ G+ C+H Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEH 4142 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.446 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,541,542 Number of Sequences: 37866 Number of extensions: 3240867 Number of successful extensions: 13266 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 149 Number of HSP's successfully gapped in prelim test: 372 Number of HSP's that attempted gapping in prelim test: 9120 Number of HSP's gapped (non-prelim): 3446 length of query: 1429 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1314 effective length of database: 13,892,928 effective search space: 18255307392 effective search space used: 18255307392 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.