Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 214010185
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform
4 [Homo sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform ... 1034 0.0
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 766 0.0
gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ... 764 0.0
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 757 0.0
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 383 e-106
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 383 e-106
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 383 e-106
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 382 e-106
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 382 e-106
gi|4885065 amyloid precursor-like protein 1 isoform 2 precursor ... 302 4e-82
gi|67782338 amyloid precursor-like protein 1 isoform 1 precursor... 301 7e-82
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 55 2e-07
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 55 2e-07
gi|221139761 zinc finger protein 853 [Homo sapiens] 47 3e-05
gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sap... 47 6e-05
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 44 3e-04
gi|38044112 restin isoform b [Homo sapiens] 44 3e-04
gi|4506751 restin isoform a [Homo sapiens] 44 3e-04
gi|154354979 myosin X [Homo sapiens] 43 6e-04
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 43 6e-04
gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo sap... 43 6e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 42 0.001
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 42 0.001
gi|110611218 ribosome binding protein 1 [Homo sapiens] 42 0.002
gi|110611220 ribosome binding protein 1 [Homo sapiens] 42 0.002
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 42 0.002
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 41 0.003
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 40 0.005
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 40 0.005
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 40 0.005
>gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform 4
[Homo sapiens]
Length = 522
Score = 1034 bits (2674), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
Query: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
Query: 121 KQCKSRFVTPFKCLVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVK 180
KQCKSRFVTPFKCLVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVK
Sbjct: 121 KQCKSRFVTPFKCLVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVK 180
Query: 181 KEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRR 240
KEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRR
Sbjct: 181 KEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRR 240
Query: 241 MALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV 300
MALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV
Sbjct: 241 MALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV 300
Query: 301 MTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVS 360
MTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVS
Sbjct: 301 MTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVS 360
Query: 361 SEESEEIPPFHPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDV 420
SEESEEIPPFHPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDV
Sbjct: 361 SEESEEIPPFHPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDV 420
Query: 421 KEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQY 480
KEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQY
Sbjct: 421 KEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQY 480
Query: 481 GTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 522
GTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 481 GTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 522
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 766 bits (1978), Expect = 0.0
Identities = 388/391 (99%), Positives = 390/391 (99%)
Query: 132 KCLVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 191
K ++PPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK
Sbjct: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420
Query: 192 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 251
NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ
Sbjct: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480
Query: 252 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311
SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR
Sbjct: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
Query: 312 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 371
NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH
Sbjct: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600
Query: 372 PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG 431
PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG
Sbjct: 601 PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG 660
Query: 432 GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD 491
GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD
Sbjct: 661 GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD 720
Query: 492 PMLTPEERHLNKMQNHGYENPTYKYLEQMQI 522
PMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 721 PMLTPEERHLNKMQNHGYENPTYKYLEQMQI 751
Score = 276 bits (706), Expect = 3e-74
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
Query: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
Query: 121 KQCKSRFVTPFKCLV 135
KQCKSRFVTPFKCLV
Sbjct: 121 KQCKSRFVTPFKCLV 135
>gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3
[Homo sapiens]
Length = 695
Score = 764 bits (1972), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 135 VPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP 194
VPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP
Sbjct: 308 VPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP 367
Query: 195 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 254
KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP
Sbjct: 368 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 427
Query: 255 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 314
PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS
Sbjct: 428 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 487
Query: 315 LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH 374
LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH
Sbjct: 488 LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH 547
Query: 375 PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE 434
PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE
Sbjct: 548 PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE 607
Query: 435 EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPML 494
EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPML
Sbjct: 608 EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPML 667
Query: 495 TPEERHLNKMQNHGYENPTYKYLEQMQI 522
TPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 668 TPEERHLNKMQNHGYENPTYKYLEQMQI 695
Score = 276 bits (706), Expect = 3e-74
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
Query: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
Query: 121 KQCKSRFVTPFKCLV 135
KQCKSRFVTPFKCLV
Sbjct: 121 KQCKSRFVTPFKCLV 135
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 757 bits (1955), Expect = 0.0
Identities = 388/403 (96%), Positives = 390/403 (96%), Gaps = 12/403 (2%)
Query: 132 KCLVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 191
K ++PPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK
Sbjct: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420
Query: 192 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 251
NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ
Sbjct: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480
Query: 252 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311
SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR
Sbjct: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
Query: 312 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 371
NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH
Sbjct: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600
Query: 372 PFHPFPALPENE------------GSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD 419
PFHPFPALPENE GSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD
Sbjct: 601 PFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD 660
Query: 420 VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ 479
VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ
Sbjct: 661 VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ 720
Query: 480 YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 522
YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 721 YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 763
Score = 276 bits (706), Expect = 3e-74
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
Query: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
Query: 121 KQCKSRFVTPFKCLV 135
KQCKSRFVTPFKCLV
Sbjct: 121 KQCKSRFVTPFKCLV 135
>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
sapiens]
Length = 695
Score = 383 bits (984), Expect = e-106
Identities = 216/411 (52%), Positives = 278/411 (67%), Gaps = 29/411 (7%)
Query: 135 VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 193
VP T T D VD Y ET D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 289 VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 348
Query: 194 PKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSD 253
PKA+++ +IQHFQ V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+
Sbjct: 349 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 408
Query: 254 PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 313
PPRP + L++YVRAE KDR HT++H++HV VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 409 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 468
Query: 314 SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVD 356
SLSLLY VP VA+EIQ+E+DELLQ+++ A+M D S++ET
Sbjct: 469 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 528
Query: 357 VR---VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDE 410
V V+ E S +++ P+H F PA ENE V + A+ +
Sbjct: 529 VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLT 584
Query: 411 NMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVI 470
N+ +E +VK M G E + + ED + A+IGL+V V IATVIVI
Sbjct: 585 NIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVI 643
Query: 471 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 521
+LVML+K+QY +I HG+VEVD +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 644 TLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 694
Score = 152 bits (385), Expect = 5e-37
Identities = 75/123 (60%), Positives = 93/123 (75%), Gaps = 10/123 (8%)
Query: 15 LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDP 74
L LLLL TA AL + NAG +AEPQIAMFCG+LNMH+N+Q GKW+ DP
Sbjct: 5 LALLLLAAWTARALEVP-----TDGNAGL---LAEPQIAMFCGRLNMHMNVQNGKWDSDP 56
Query: 75 TGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKS--RFVTPFK 132
+GTK+C +TKE +LQYCQE+YPELQITNV+EANQ V+I NWC+R +KQCK+ FV P++
Sbjct: 57 SGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYR 116
Query: 133 CLV 135
CLV
Sbjct: 117 CLV 119
>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
sapiens]
Length = 639
Score = 383 bits (984), Expect = e-106
Identities = 216/411 (52%), Positives = 278/411 (67%), Gaps = 29/411 (7%)
Query: 135 VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 193
VP T T D VD Y ET D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 233 VPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 292
Query: 194 PKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSD 253
PKA+++ +IQHFQ V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+
Sbjct: 293 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 352
Query: 254 PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 313
PPRP + L++YVRAE KDR HT++H++HV VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 353 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 412
Query: 314 SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVD 356
SLSLLY VP VA+EIQ+E+DELLQ+++ A+M D S++ET
Sbjct: 413 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 472
Query: 357 VR---VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDE 410
V V+ E S +++ P+H F PA ENE V + A+ +
Sbjct: 473 VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLT 528
Query: 411 NMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVI 470
N+ +E +VK M G E + + ED + A+IGL+V V IATVIVI
Sbjct: 529 NIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVI 587
Query: 471 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 521
+LVML+K+QY +I HG+VEVD +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 588 TLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 638
Score = 68.2 bits (165), Expect = 2e-11
Identities = 30/45 (66%), Positives = 38/45 (84%), Gaps = 2/45 (4%)
Query: 93 EMYPELQITNVMEANQRVSIDNWCRRDKKQCKS--RFVTPFKCLV 135
E+YPELQITNV+EANQ V+I NWC+R +KQCK+ FV P++CLV
Sbjct: 19 EVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLV 63
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 383 bits (983), Expect = e-106
Identities = 215/411 (52%), Positives = 278/411 (67%), Gaps = 29/411 (7%)
Query: 135 VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 193
+P T T D VD Y ET D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 345 IPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 404
Query: 194 PKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSD 253
PKA+++ +IQHFQ V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+
Sbjct: 405 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 464
Query: 254 PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 313
PPRP + L++YVRAE KDR HT++H++HV VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 465 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 524
Query: 314 SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVD 356
SLSLLY VP VA+EIQ+E+DELLQ+++ A+M D S++ET
Sbjct: 525 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 584
Query: 357 VR---VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDE 410
V V+ E S +++ P+H F PA ENE V + A+ +
Sbjct: 585 VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLT 640
Query: 411 NMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVI 470
N+ +E +VK M G E + + ED + A+IGL+V V IATVIVI
Sbjct: 641 NIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVI 699
Query: 471 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 521
+LVML+K+QY +I HG+VEVD +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 700 TLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 750
Score = 152 bits (385), Expect = 5e-37
Identities = 75/123 (60%), Positives = 93/123 (75%), Gaps = 10/123 (8%)
Query: 15 LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDP 74
L LLLL TA AL + NAG +AEPQIAMFCG+LNMH+N+Q GKW+ DP
Sbjct: 5 LALLLLAAWTARALEVP-----TDGNAGL---LAEPQIAMFCGRLNMHMNVQNGKWDSDP 56
Query: 75 TGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKS--RFVTPFK 132
+GTK+C +TKE +LQYCQE+YPELQITNV+EANQ V+I NWC+R +KQCK+ FV P++
Sbjct: 57 SGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYR 116
Query: 133 CLV 135
CLV
Sbjct: 117 CLV 119
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 382 bits (981), Expect = e-106
Identities = 215/411 (52%), Positives = 278/411 (67%), Gaps = 29/411 (7%)
Query: 135 VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 193
+P T T D VD Y ET D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 364 LPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 423
Query: 194 PKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSD 253
PKA+++ +IQHFQ V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+
Sbjct: 424 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 483
Query: 254 PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 313
PPRP + L++YVRAE KDR HT++H++HV VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 484 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 543
Query: 314 SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVD 356
SLSLLY VP VA+EIQ+E+DELLQ+++ A+M D S++ET
Sbjct: 544 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 603
Query: 357 VR---VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDE 410
V V+ E S +++ P+H F PA ENE V + A+ +
Sbjct: 604 VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLT 659
Query: 411 NMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVI 470
N+ +E +VK M G E + + ED + A+IGL+V V IATVIVI
Sbjct: 660 NIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVI 718
Query: 471 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 521
+LVML+K+QY +I HG+VEVD +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 719 TLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 769
Score = 152 bits (385), Expect = 5e-37
Identities = 75/123 (60%), Positives = 93/123 (75%), Gaps = 10/123 (8%)
Query: 15 LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDP 74
L LLLL TA AL + NAG +AEPQIAMFCG+LNMH+N+Q GKW+ DP
Sbjct: 5 LALLLLAAWTARALEVP-----TDGNAGL---LAEPQIAMFCGRLNMHMNVQNGKWDSDP 56
Query: 75 TGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKS--RFVTPFK 132
+GTK+C +TKE +LQYCQE+YPELQITNV+EANQ V+I NWC+R +KQCK+ FV P++
Sbjct: 57 SGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYR 116
Query: 133 CLV 135
CLV
Sbjct: 117 CLV 119
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 382 bits (981), Expect = e-106
Identities = 215/411 (52%), Positives = 278/411 (67%), Gaps = 29/411 (7%)
Query: 135 VPPTPLPTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNL 193
+P T T D VD Y ET D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNL
Sbjct: 308 LPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNL 367
Query: 194 PKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSD 253
PKA+++ +IQHFQ V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+
Sbjct: 368 PKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV 427
Query: 254 PPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQ 313
PPRP + L++YVRAE KDR HT++H++HV VDP+KAAQ++SQVMTHL VI ER NQ
Sbjct: 428 PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQ 487
Query: 314 SLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVD 356
SLSLLY VP VA+EIQ+E+DELLQ+++ A+M D S++ET
Sbjct: 488 SLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTT 547
Query: 357 VR---VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDE 410
V V+ E S +++ P+H F PA ENE V + A+ +
Sbjct: 548 VELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLT 603
Query: 411 NMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVI 470
N+ +E +VK M G E + + ED + A+IGL+V V IATVIVI
Sbjct: 604 NIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVI 662
Query: 471 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 521
+LVML+K+QY +I HG+VEVD +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 663 TLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 713
Score = 68.2 bits (165), Expect = 2e-11
Identities = 30/45 (66%), Positives = 38/45 (84%), Gaps = 2/45 (4%)
Query: 93 EMYPELQITNVMEANQRVSIDNWCRRDKKQCKS--RFVTPFKCLV 135
E+YPELQITNV+EANQ V+I NWC+R +KQCK+ FV P++CLV
Sbjct: 19 EVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLV 63
>gi|4885065 amyloid precursor-like protein 1 isoform 2 precursor
[Homo sapiens]
Length = 650
Score = 302 bits (774), Expect = 4e-82
Identities = 171/386 (44%), Positives = 239/386 (61%), Gaps = 22/386 (5%)
Query: 135 VPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP 194
V PTP PT+ VD+YF + +EH F +AK LE R +++ V +EW A+ Q+KNLP
Sbjct: 284 VTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLP 343
Query: 195 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 254
KA+RQ L +HFQ++++ LE++ + E+Q+LVETH RV A++ND+RR ALE +LAALQ+DP
Sbjct: 344 KADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADP 403
Query: 255 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 314
P+ R+L ALRRY+RAE K++ HT+RHYQHV AVDPEKA QM+ QV THL VIEER NQS
Sbjct: 404 PQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQS 463
Query: 315 LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH 374
L LL + P++AQE++ +I ELL + + E P S ++ PP
Sbjct: 464 LGLLDQNPHLAQELRPQIQELLHSEHLGPSEL-----EAPAPGGSSEDKGGLQPPDSKDD 518
Query: 375 PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE 434
LP+ G EQD S K N + V + E
Sbjct: 519 TPMTLPK----GSTEQDAA----------SPEKEKMNPLEQYERKVNASVPRGFPFHSSE 564
Query: 435 EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVML-RKRQYGTISHGIVEVDPM 493
+R+ + P +S A+ GLL++ ++IV+S+++L RK+ YG ISHG+VEVDPM
Sbjct: 565 IQRDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPM 622
Query: 494 LTPEERHLNKMQNHGYENPTYKYLEQ 519
LT EE+ L ++Q HGYENPTY++LE+
Sbjct: 623 LTLEEQQLRELQRHGYENPTYRFLEE 648
Score = 90.9 bits (224), Expect = 3e-18
Identities = 48/124 (38%), Positives = 70/124 (56%), Gaps = 10/124 (8%)
Query: 15 LLLLLLVGLTAPAL-ALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPD 73
L LLLL+ PA+ +LAG + G A Q+A CG+L +H +++TG+WEPD
Sbjct: 24 LPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPD 77
Query: 74 PTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWC---RRDKKQCKSRFVTP 130
P ++ C + VL+YC++MYPELQI V +A Q + ++ WC R V P
Sbjct: 78 PQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVP 137
Query: 131 FKCL 134
F+CL
Sbjct: 138 FRCL 141
>gi|67782338 amyloid precursor-like protein 1 isoform 1 precursor
[Homo sapiens]
Length = 651
Score = 301 bits (772), Expect = 7e-82
Identities = 171/386 (44%), Positives = 238/386 (61%), Gaps = 21/386 (5%)
Query: 135 VPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP 194
V PTP PT+ VD+YF + +EH F +AK LE R +++ V +EW A+ Q+KNLP
Sbjct: 284 VTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLP 343
Query: 195 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 254
KA+RQ L +HFQ++++ LE++ + E+Q+LVETH RV A++ND+RR ALE +LAALQ+DP
Sbjct: 344 KADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADP 403
Query: 255 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 314
P+ R+L ALRRY+RAE K++ HT+RHYQHV AVDPEKA QM+ QV THL VIEER NQS
Sbjct: 404 PQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQS 463
Query: 315 LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH 374
L LL + P++AQE++ +I ELL + + A SSE+ + P P
Sbjct: 464 LGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGG------SSEDKGGLQP--PDS 515
Query: 375 PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE 434
P G EQD S K N + V + E
Sbjct: 516 KDADTPMTLPKGSTEQDAA----------SPEKEKMNPLEQYERKVNASVPRGFPFHSSE 565
Query: 435 EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVML-RKRQYGTISHGIVEVDPM 493
+R+ + P +S A+ GLL++ ++IV+S+++L RK+ YG ISHG+VEVDPM
Sbjct: 566 IQRDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPM 623
Query: 494 LTPEERHLNKMQNHGYENPTYKYLEQ 519
LT EE+ L ++Q HGYENPTY++LE+
Sbjct: 624 LTLEEQQLRELQRHGYENPTYRFLEE 649
Score = 90.9 bits (224), Expect = 3e-18
Identities = 48/124 (38%), Positives = 70/124 (56%), Gaps = 10/124 (8%)
Query: 15 LLLLLLVGLTAPAL-ALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPD 73
L LLLL+ PA+ +LAG + G A Q+A CG+L +H +++TG+WEPD
Sbjct: 24 LPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPD 77
Query: 74 PTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWC---RRDKKQCKSRFVTP 130
P ++ C + VL+YC++MYPELQI V +A Q + ++ WC R V P
Sbjct: 78 PQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVP 137
Query: 131 FKCL 134
F+CL
Sbjct: 138 FRCL 141
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/297 (20%), Positives = 131/297 (44%), Gaps = 31/297 (10%)
Query: 85 EEVLQYCQEMYPELQITNVMEANQRVS-IDNWCRRDKKQCKSRFVTPFKCLVPPTPLPTN 143
E + Q C ++ EL++ + + +S + R+K + + + L+ L
Sbjct: 523 ENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQ 582
Query: 144 DVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQ 203
++++ S Q + +QL+ + R+ +E EE E Q + K+ ++ +
Sbjct: 583 NLEIQLSQS---------QTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVL 633
Query: 204 HFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQA 263
FQ M + EKE + + L + H A +++ L D R ++E + ++ + LQ
Sbjct: 634 AFQTMEEEKEKEQRALENHLQQKHSAELQS-LKDAHRESMEGFRIEMEQE-------LQT 685
Query: 264 LRRYVRAENKDRLHTIR---HYQHVLAVD---PEKAAQMKSQVMTHLHVIEERRNQSLSL 317
LR + E K L ++R ++QH A+D ++ + M I+ R QS
Sbjct: 686 LRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEH 745
Query: 318 LYKVPYVAQEIQ------EEIDELLQEQRADMDQFTASISETPVDV-RVSSEESEEI 367
+ ++ + +E++ E+D+ +Q ++ T + ++ R+ SE +++I
Sbjct: 746 ICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQI 802
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/297 (20%), Positives = 131/297 (44%), Gaps = 31/297 (10%)
Query: 85 EEVLQYCQEMYPELQITNVMEANQRVS-IDNWCRRDKKQCKSRFVTPFKCLVPPTPLPTN 143
E + Q C ++ EL++ + + +S + R+K + + + L+ L
Sbjct: 643 ENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQ 702
Query: 144 DVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQ 203
++++ S Q + +QL+ + R+ +E EE E Q + K+ ++ +
Sbjct: 703 NLEIQLSQS---------QTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVL 753
Query: 204 HFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQA 263
FQ M + EKE + + L + H A +++ L D R ++E + ++ + LQ
Sbjct: 754 AFQTMEEEKEKEQRALENHLQQKHSAELQS-LKDAHRESMEGFRIEMEQE-------LQT 805
Query: 264 LRRYVRAENKDRLHTIR---HYQHVLAVD---PEKAAQMKSQVMTHLHVIEERRNQSLSL 317
LR + E K L ++R ++QH A+D ++ + M I+ R QS
Sbjct: 806 LRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEH 865
Query: 318 LYKVPYVAQEIQ------EEIDELLQEQRADMDQFTASISETPVDV-RVSSEESEEI 367
+ ++ + +E++ E+D+ +Q ++ T + ++ R+ SE +++I
Sbjct: 866 ICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQI 922
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/256 (19%), Positives = 117/256 (45%), Gaps = 33/256 (12%)
Query: 157 EHARFQKAKEQLEIRHRNRMDRVKKEWE-----EAELQAKNLPKAERQTLIQHFQAMVKA 211
E + Q+A+EQ ++ + ++ + +E + + +LQ + L + + Q Q FQ +
Sbjct: 175 EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQ 234
Query: 212 LE--------KEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQA 263
L+ ++ +QQL++ A+++ L ++++ L+ L Q + + + Q
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Query: 264 LRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVM-----THLHVIEER----RNQS 314
L++ + +L ++PE+ +++ ++M + + ++R R Q
Sbjct: 295 LQQQQEQLQQQQLQP-------PPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQE 347
Query: 315 LSLLYKVPYVAQEIQEEIDEL---LQEQRADMDQFTASISETPVDVRVSSEESE-EIPPF 370
L + + ++QEE+ +L L++Q+ ++Q + TPV++ +E + E+ P
Sbjct: 348 LERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPV 407
Query: 371 HPFHPFPALPENEGSG 386
P +P G G
Sbjct: 408 QPELQLELVPAAGGGG 423
>gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo
sapiens]
Length = 410
Score = 46.6 bits (109), Expect = 6e-05
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 150 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 209
ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + +
Sbjct: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174
Query: 210 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 262
+ L +EA E QQ L+++ D R A ++ + QS PR H +
Sbjct: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232
Query: 263 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311
A R ++AE +L ++ QH + E Q + Q +H E RR
Sbjct: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 44.3 bits (103), Expect = 3e-04
Identities = 55/256 (21%), Positives = 110/256 (42%), Gaps = 43/256 (16%)
Query: 173 RNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVE 232
R ++ ++EE + + AE++ L++ + +KA+E+ A++K Q E L +
Sbjct: 239 REMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEE--ANKKMQAAEISLEEKD 296
Query: 233 AMLNDR----RRMALENYLAALQ--------------SDPPRPHRILQALRRYVRAENKD 274
+ + RM E + LQ SD R ++ +A A ++
Sbjct: 297 QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEA-----SASLRE 351
Query: 275 RLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDE 334
R IRH ++ +K QM ++ + +++++ L LL K+ ++ E E
Sbjct: 352 R---IRHLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNE---- 404
Query: 335 LLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEGSGVGEQDGGL 394
LQ + +D T + ++T V+ R + +P PF +N+ S ++ G
Sbjct: 405 -LQSR---LDYLTETQAKTEVETREIGVGCDLLPRL-PFR------QNDSSSHCQKSGSP 453
Query: 395 IGAEEKVINSKNKVDE 410
I +EE+ K +D+
Sbjct: 454 ISSEERRRRDKQHLDD 469
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/330 (19%), Positives = 142/330 (43%), Gaps = 33/330 (10%)
Query: 143 NDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLI 202
ND+ + S D++ ++ K ++L ++ R+ ++ ++ + +A A L K+ +
Sbjct: 882 NDIAEIMKMSGDNS--SQLTKMNDELRLKERD-VEELQLKLTKANENASFLQKSIEDMTV 938
Query: 203 QHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALE---NYLAALQSDPPRPHR 259
+ Q+ +A +K +K+ +E L+ +E + E Y A +
Sbjct: 939 KAEQSQQEAAKKHEEEKKE--LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE 996
Query: 260 ILQALRRYV----------RAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEE 309
ILQ L++ + R EN L + + D KAAQ M + + +
Sbjct: 997 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRK--QADKAKAAQTAEDAMQIMEQMTK 1054
Query: 310 RRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPP 369
+ ++L+ L ++Q E+D L + ++++ S V+ + E +EI
Sbjct: 1055 EKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI-- 1112
Query: 370 FHPFHPFPALPENEGSGVGEQDGGL---IGAEEKVINSKNKVDE--NMVIDETLDVKEMI 424
A + S + E++ L +G + S K++E +++ ++ L++K+
Sbjct: 1113 -ETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKR- 1170
Query: 425 FNAERVGGLEEERESVGPLREDFSLSSSAL 454
++ + +EE+ S L++ S++S+ L
Sbjct: 1171 -ESKFIKDADEEKAS---LQKSISITSALL 1196
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/330 (19%), Positives = 142/330 (43%), Gaps = 33/330 (10%)
Query: 143 NDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLI 202
ND+ + S D++ ++ K ++L ++ R+ ++ ++ + +A A L K+ +
Sbjct: 917 NDIAEIMKMSGDNS--SQLTKMNDELRLKERD-VEELQLKLTKANENASFLQKSIEDMTV 973
Query: 203 QHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALE---NYLAALQSDPPRPHR 259
+ Q+ +A +K +K+ +E L+ +E + E Y A +
Sbjct: 974 KAEQSQQEAAKKHEEEKKE--LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE 1031
Query: 260 ILQALRRYV----------RAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEE 309
ILQ L++ + R EN L + + D KAAQ M + + +
Sbjct: 1032 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRK--QADKAKAAQTAEDAMQIMEQMTK 1089
Query: 310 RRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPP 369
+ ++L+ L ++Q E+D L + ++++ S V+ + E +EI
Sbjct: 1090 EKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI-- 1147
Query: 370 FHPFHPFPALPENEGSGVGEQDGGL---IGAEEKVINSKNKVDE--NMVIDETLDVKEMI 424
A + S + E++ L +G + S K++E +++ ++ L++K+
Sbjct: 1148 -ETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKR- 1205
Query: 425 FNAERVGGLEEERESVGPLREDFSLSSSAL 454
++ + +EE+ S L++ S++S+ L
Sbjct: 1206 -ESKFIKDADEEKAS---LQKSISITSALL 1231
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 43.1 bits (100), Expect = 6e-04
Identities = 56/245 (22%), Positives = 103/245 (42%), Gaps = 40/245 (16%)
Query: 147 VYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQ 206
VY + A+ E +K +E+ + + ++E EAEL+A+ + +Q ++ Q
Sbjct: 807 VYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQ 866
Query: 207 AMVKALE--KEAASEKQQLVETHLARVEAMLNDRRRMALENYL----AALQSDPPRPHRI 260
K E +E +K+ + R+E + D +RM + L A+LQ R +
Sbjct: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
Query: 261 L--------QALRRYVRAENKDRL-HTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311
L +A + ++ + N D + +R+ + L+V E ++++ EE+
Sbjct: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAES------ACEEKP 980
Query: 312 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTAS--------ISETPVDVRVSSEE 363
N + S Y +EE+DE + AD D F S + +R S +
Sbjct: 981 NFNFSQPYP--------EEEVDEGFE---ADDDAFKDSPNPSEHGHSDQRTSGIRTSDDS 1029
Query: 364 SEEIP 368
SEE P
Sbjct: 1030 SEEDP 1034
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 43.1 bits (100), Expect = 6e-04
Identities = 51/210 (24%), Positives = 96/210 (45%), Gaps = 30/210 (14%)
Query: 150 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 209
E S ++ EHA Q +E + ++ + KKE E EL+ RQT I+ Q V
Sbjct: 187 ERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYV 246
Query: 210 KALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYL---AALQSDPPRPHRILQALRR 266
+ ++E +QQL E + +LN+R LE + A LQ + + + + L +
Sbjct: 247 QKSKEELQKLEQQLKE------QKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQ 300
Query: 267 YVRAENKDRLHTIRHYQ---HVLAVDPEKAAQMKSQVMTHLHVIEER-----------RN 312
EN+ + ++ + H + +D K +++ Q+ LH E++ +N
Sbjct: 301 ----ENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKN 356
Query: 313 QSLSLLYKVPYVAQEIQ---EEIDELLQEQ 339
Q + L +V ++ + + +DELL+E+
Sbjct: 357 QIVGLEREVEASKKQAELDRKAMDELLRER 386
Score = 30.0 bits (66), Expect = 5.4
Identities = 34/188 (18%), Positives = 81/188 (43%), Gaps = 13/188 (6%)
Query: 161 FQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEK 220
++K + EI+ + + + + + L +KNL +A+ + I + +K + + K
Sbjct: 473 YRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDE--ITDMKRKLKIMIHQVDELK 530
Query: 221 QQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIR 280
+ + A V+ L +R +E L+++ + + + ++ + + +R
Sbjct: 531 EDISAKESALVKLHLEQQR---IEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLR 587
Query: 281 HYQHVLAVDPEKAAQMKS--QVMTHLHVIEE---RRNQSLSLLYKVPYVAQEIQEEIDEL 335
+ D E+ Q K QV++ ++ RRN L+LLY+ + Q + + +
Sbjct: 588 I---IAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQ 644
Query: 336 LQEQRADM 343
++ DM
Sbjct: 645 YNQRLEDM 652
>gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo
sapiens]
Length = 307
Score = 43.1 bits (100), Expect = 6e-04
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 150 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 209
ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + +
Sbjct: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174
Query: 210 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYV 268
+ L +EA E QQ L+++ D R A ++ + QS A R +
Sbjct: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSS---TWARSWAYRDSL 229
Query: 269 RAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311
+AE +L ++ QH + E Q + Q +H E RR
Sbjct: 230 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 272
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 42.0 bits (97), Expect = 0.001
Identities = 50/239 (20%), Positives = 97/239 (40%), Gaps = 28/239 (11%)
Query: 152 SADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQ--AKNLPKAERQTLIQHFQAMV 209
SA+ +HAR ++ + + RHR D+ ++EWE + + A+ + ER L Q +
Sbjct: 115 SAEGGKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ----LE 170
Query: 210 KALEKEAASEKQQLVETHLARVEAMLNDRR-------------RMALENYLAALQS---- 252
+ E+E +QQ + E +RR R E+Y +++
Sbjct: 171 RKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWS 230
Query: 253 -DPPRPHRILQAL---RRYVRAENKDRLHTIRHYQHVLAVDPE-KAAQMKSQVMTHLHVI 307
PPRP R L R+ V+ E + + Q + + + +A+ S
Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE 290
Query: 308 EERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEE 366
EE + ++E +EE +E +E ++ ++ + +E + +S +E E
Sbjct: 291 EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/247 (23%), Positives = 97/247 (39%), Gaps = 20/247 (8%)
Query: 162 QKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAAS--- 218
QK +EQ E R R R + ++ +LQ + K + L+Q Q + L +E
Sbjct: 327 QKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRR 386
Query: 219 ----EKQQLVETHLARVE-AMLNDRRRMALENYLAALQSD-----PPRPHRILQALRRYV 268
E QQ +E L E A + + M L+ AA Q R+ +AL+ V
Sbjct: 387 SQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEV 446
Query: 269 RAENKDRLHTIRHYQHVLAVDPE----KAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYV 324
+A + ++R Q L + E + Q+K + ++ ++ + + + +
Sbjct: 447 KARRDE--ESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRS 504
Query: 325 AQEIQEEIDELLQ-EQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENE 383
Q+ Q++++E+ Q QRAD D A V + HP P P
Sbjct: 505 LQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPVTS 564
Query: 384 GSGVGEQ 390
S G Q
Sbjct: 565 SSFSGFQ 571
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/242 (21%), Positives = 108/242 (44%), Gaps = 22/242 (9%)
Query: 140 LPTNDVDVYFETSADDNEHARFQKAK-EQLEIRHRNRMDRVKKEWEEA----ELQAKNLP 194
L +++ +V + H + Q+A+ E ++ R R E +A ++QA
Sbjct: 489 LQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAE 548
Query: 195 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 254
++QT ++ ++ V LEKEA ++ + + + + L ++ A+E A Q+
Sbjct: 549 ADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNND--LREKNWKAMEALATAEQACK 606
Query: 255 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 314
+ H + QA +E + L + + +LA+ PE + + L ++E+
Sbjct: 607 EKLHSLTQAKE---ESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEK---G 660
Query: 315 LSLLYKVPYVAQEIQE------EIDELLQEQRADMDQFTASISETP---VDVRVSSEESE 365
+LL P A+ + E +E +A+ DQ+ + ++ET D++ S EE E
Sbjct: 661 PTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEE 720
Query: 366 EI 367
++
Sbjct: 721 QV 722
Score = 30.8 bits (68), Expect = 3.1
Identities = 63/312 (20%), Positives = 124/312 (39%), Gaps = 39/312 (12%)
Query: 159 ARFQKAKEQLEIRHR-------NRMDRVKKEW-----EEAELQAKNLPKAERQTLIQHFQ 206
A F+K QL+ HR R+D V +E A L+A E+Q +
Sbjct: 427 AAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELH 486
Query: 207 AMVKALEKEAASEKQQLVETHLARVEAML-NDRRRMALENYLAALQSDPPRPHRILQALR 265
+ +++ E E S+ ++L H EA N + + + A L++ R + +QA
Sbjct: 487 SKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQA-- 544
Query: 266 RYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVA 325
+AE + ++ + ++ ++A +++ V + R ++ + +
Sbjct: 545 --SQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAE 602
Query: 326 QEIQEEIDELLQEQRAD-----------MDQFTASISETPVDVRVSSEE-----SEEIPP 369
Q +E++ L Q + M+ A + E V + + E E+ P
Sbjct: 603 QACKEKLHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPT 662
Query: 370 FHPFHPFPALPENEGSG---VGEQDGGLIGAEEKVINSKNKVDENMVID--ETLDVKEMI 424
P PA P ++ + E+ + AE S E M+ D ++++ +E +
Sbjct: 663 LLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQV 722
Query: 425 FNAERVGGLEEE 436
+ A +VG EEE
Sbjct: 723 WRA-KVGAAEEE 733
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/242 (21%), Positives = 108/242 (44%), Gaps = 22/242 (9%)
Query: 140 LPTNDVDVYFETSADDNEHARFQKAK-EQLEIRHRNRMDRVKKEWEEA----ELQAKNLP 194
L +++ +V + H + Q+A+ E ++ R R E +A ++QA
Sbjct: 489 LQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAE 548
Query: 195 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 254
++QT ++ ++ V LEKEA ++ + + + + L ++ A+E A Q+
Sbjct: 549 ADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNND--LREKNWKAMEALATAEQACK 606
Query: 255 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 314
+ H + QA +E + L + + +LA+ PE + + L ++E+
Sbjct: 607 EKLHSLTQAKE---ESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEK---G 660
Query: 315 LSLLYKVPYVAQEIQE------EIDELLQEQRADMDQFTASISETP---VDVRVSSEESE 365
+LL P A+ + E +E +A+ DQ+ + ++ET D++ S EE E
Sbjct: 661 PTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEE 720
Query: 366 EI 367
++
Sbjct: 721 QV 722
Score = 30.8 bits (68), Expect = 3.1
Identities = 63/312 (20%), Positives = 124/312 (39%), Gaps = 39/312 (12%)
Query: 159 ARFQKAKEQLEIRHR-------NRMDRVKKEW-----EEAELQAKNLPKAERQTLIQHFQ 206
A F+K QL+ HR R+D V +E A L+A E+Q +
Sbjct: 427 AAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELH 486
Query: 207 AMVKALEKEAASEKQQLVETHLARVEAML-NDRRRMALENYLAALQSDPPRPHRILQALR 265
+ +++ E E S+ ++L H EA N + + + A L++ R + +QA
Sbjct: 487 SKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQA-- 544
Query: 266 RYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVA 325
+AE + ++ + ++ ++A +++ V + R ++ + +
Sbjct: 545 --SQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAE 602
Query: 326 QEIQEEIDELLQEQRAD-----------MDQFTASISETPVDVRVSSEE-----SEEIPP 369
Q +E++ L Q + M+ A + E V + + E E+ P
Sbjct: 603 QACKEKLHSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPT 662
Query: 370 FHPFHPFPALPENEGSG---VGEQDGGLIGAEEKVINSKNKVDENMVID--ETLDVKEMI 424
P PA P ++ + E+ + AE S E M+ D ++++ +E +
Sbjct: 663 LLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQV 722
Query: 425 FNAERVGGLEEE 436
+ A +VG EEE
Sbjct: 723 WRA-KVGAAEEE 733
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/275 (18%), Positives = 115/275 (41%), Gaps = 34/275 (12%)
Query: 78 KSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVPP 137
K C E +EE+L+ Q+ E ++++ E Q+ + R +++ +
Sbjct: 624 KLCQEEEEEILRLHQQK--EQSLSSLRERLQKAIEEEEARMREEESQR------------ 669
Query: 138 TPLPTNDVDVYFETSADDNE-----HARFQKAKEQLEI-----------RHRNRMDRVKK 181
L V T AD+++ A QK +E+LE ++R ++++K+
Sbjct: 670 --LSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKE 727
Query: 182 EWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRM 241
E E +E + A ++ +Q + ++ KEA + ++ L R+ + L + R
Sbjct: 728 EIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHRE 787
Query: 242 ALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVL-AVDPEKAAQMKSQV 300
+ + +Q + LQ V + + + Y+H L ++ EK +++ +
Sbjct: 788 VVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEH 847
Query: 301 MTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDEL 335
L ++E Q ++ + Y A+E ++ + L
Sbjct: 848 ERRLDKMKEEHQQVMAKA-REQYEAEERKQRAELL 881
Score = 30.8 bits (68), Expect = 3.1
Identities = 39/186 (20%), Positives = 76/186 (40%), Gaps = 41/186 (22%)
Query: 181 KEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRR 240
K EEA Q L + +R L + M + EK E+++++ H + +++ + R R
Sbjct: 593 KAMEEAVAQV--LEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRER 650
Query: 241 MALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV 300
+ A++ + R +R E RL +R AQ++S
Sbjct: 651 LQ-----KAIEEEEAR-----------MREEESQRLSWLR-------------AQVQSST 681
Query: 301 MTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVS 360
I + SL Q+++EE++ + +RA ++Q + E + +
Sbjct: 682 QADEDQIRAEQEASL----------QKLREELESQQKAERASLEQKNRQMLEQLKEEIEA 731
Query: 361 SEESEE 366
SE+SE+
Sbjct: 732 SEKSEQ 737
Score = 30.4 bits (67), Expect = 4.1
Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 158 HARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAA 217
H ++ + LE+ R VK E+Q + + ++Q L Q +K+ +EA
Sbjct: 917 HREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKS--EEAT 974
Query: 218 SEKQQLVE-----THLARVEAMLND------RRRMALENYLAALQSDPPRPHRILQALRR 266
+ QQL E THL + L + R++ LE+ + LQ+ + + +L
Sbjct: 975 ATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSL-- 1032
Query: 267 YVRAENKDRLHTIR 280
AE + + H +R
Sbjct: 1033 --EAEAQKKQHLLR 1044
Score = 30.0 bits (66), Expect = 5.4
Identities = 42/205 (20%), Positives = 83/205 (40%), Gaps = 21/205 (10%)
Query: 162 QKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAA---- 217
Q + LE + +K +E E + L + + Q+L + + KA+E+E A
Sbjct: 605 QDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMRE 664
Query: 218 SEKQQL------VETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAE 271
E Q+L V++ E + + +L+ L+S L+ R + +
Sbjct: 665 EESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQ 724
Query: 272 NKDRLH-TIRHYQHVLAVDPEKA-----AQMKSQVMTHLHVIEERRNQSL-----SLLYK 320
K+ + + + Q L EKA Q++ + + +E+ + L SL K
Sbjct: 725 LKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAK 784
Query: 321 VPYVAQEIQEEIDELLQEQRADMDQ 345
V +Q++I E Q++ A + +
Sbjct: 785 HREVVSSLQKKIQEAQQKEEAQLQK 809
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/229 (22%), Positives = 92/229 (40%), Gaps = 24/229 (10%)
Query: 157 EHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEA 216
+ R Q+ +EQ E R ++R +KE EE + + ER+ + + + LE+E
Sbjct: 422 QQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQ-----EYIRRQLEEE- 475
Query: 217 ASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRL 276
++++ L + +AML + R +E + A R R LQ + Y+ + D
Sbjct: 476 -QRHLEVLQQQLLQEQAMLLECRWREMEEHRQA-----ERLQRQLQQEQAYLLSLQHD-- 527
Query: 277 HTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELL 336
H H QH P + + K H E + + Y+ A+E+++ +
Sbjct: 528 HRRPHPQHSQQPPPPQQERSKPS----FHAPEPKAH------YEPADRAREVEDRFRKTN 577
Query: 337 QEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEGS 385
+ T + E PV R S + HP PA P+ + S
Sbjct: 578 HSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWS 626
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 40.0 bits (92), Expect = 0.005
Identities = 55/272 (20%), Positives = 116/272 (42%), Gaps = 43/272 (15%)
Query: 135 VPPTPLPTNDVD---VYFETSADDNEHARFQKAKEQLEIR----HRNRMDRVKKEW---- 183
VPP P P+ + + + E R ++A+++ +++ H+ ++++V+ EW
Sbjct: 73 VPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQ-EWKSKM 131
Query: 184 --EEAELQ-----AKNLPKAERQTLIQHFQAM--------VKALEKEAASEK----QQLV 224
++A+LQ A+ K + ++ + M + L+KE A E+ QQ V
Sbjct: 132 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 225 ETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQH 284
E RV+ + D + E + SD L+ L A KD L +R
Sbjct: 192 EALKERVDELTTDLEILKAE--IEEKGSDGAASSYQLKQLEEQ-NARLKDALVRMRDLSS 248
Query: 285 VLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEID---------EL 335
+ K ++ + L V+ ++R + L + E++E++D E+
Sbjct: 249 SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEM 308
Query: 336 LQEQRADMDQFTASISETPVDVRVSSEESEEI 367
L ++ ++++ + ET D+ +E ++E+
Sbjct: 309 LTDRNLNLEEKVRELRETVGDLEAMNEMNDEL 340
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 40.0 bits (92), Expect = 0.005
Identities = 55/272 (20%), Positives = 116/272 (42%), Gaps = 43/272 (15%)
Query: 135 VPPTPLPTNDVD---VYFETSADDNEHARFQKAKEQLEIR----HRNRMDRVKKEW---- 183
VPP P P+ + + + E R ++A+++ +++ H+ ++++V+ EW
Sbjct: 187 VPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQ-EWKSKM 245
Query: 184 --EEAELQ-----AKNLPKAERQTLIQHFQAM--------VKALEKEAASEK----QQLV 224
++A+LQ A+ K + ++ + M + L+KE A E+ QQ V
Sbjct: 246 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 305
Query: 225 ETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQH 284
E RV+ + D + E + SD L+ L A KD L +R
Sbjct: 306 EALKERVDELTTDLEILKAE--IEEKGSDGAASSYQLKQLEEQ-NARLKDALVRMRDLSS 362
Query: 285 VLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEID---------EL 335
+ K ++ + L V+ ++R + L + E++E++D E+
Sbjct: 363 SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEM 422
Query: 336 LQEQRADMDQFTASISETPVDVRVSSEESEEI 367
L ++ ++++ + ET D+ +E ++E+
Sbjct: 423 LTDRNLNLEEKVRELRETVGDLEAMNEMNDEL 454
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 40.0 bits (92), Expect = 0.005
Identities = 55/272 (20%), Positives = 116/272 (42%), Gaps = 43/272 (15%)
Query: 135 VPPTPLPTNDVD---VYFETSADDNEHARFQKAKEQLEIR----HRNRMDRVKKEW---- 183
VPP P P+ + + + E R ++A+++ +++ H+ ++++V+ EW
Sbjct: 73 VPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQ-EWKSKM 131
Query: 184 --EEAELQ-----AKNLPKAERQTLIQHFQAM--------VKALEKEAASEK----QQLV 224
++A+LQ A+ K + ++ + M + L+KE A E+ QQ V
Sbjct: 132 QEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 225 ETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQH 284
E RV+ + D + E + SD L+ L A KD L +R
Sbjct: 192 EALKERVDELTTDLEILKAE--IEEKGSDGAASSYQLKQLEEQ-NARLKDALVRMRDLSS 248
Query: 285 VLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEID---------EL 335
+ K ++ + L V+ ++R + L + E++E++D E+
Sbjct: 249 SEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEM 308
Query: 336 LQEQRADMDQFTASISETPVDVRVSSEESEEI 367
L ++ ++++ + ET D+ +E ++E+
Sbjct: 309 LTDRNLNLEEKVRELRETVGDLEAMNEMNDEL 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,520,393
Number of Sequences: 37866
Number of extensions: 879753
Number of successful extensions: 4540
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 274
Number of HSP's that attempted gapping in prelim test: 4070
Number of HSP's gapped (non-prelim): 684
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.