Guide to the Human Genome
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Search of human proteins with 214010181

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform
2 [Homo sapiens]
         (751 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ...  1522   0.0  
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ...  1513   0.0  
gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ...  1205   0.0  
gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform ...   766   0.0  
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa...   757   0.0  
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap...   746   0.0  
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s...   661   0.0  
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa...   638   0.0  
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s...   553   e-157
gi|4885065 amyloid precursor-like protein 1 isoform 2 precursor ...   302   9e-82
gi|67782338 amyloid precursor-like protein 1 isoform 1 precursor...   301   1e-81
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi...    80   7e-15
gi|28212222 WFIKKN2 protein [Homo sapiens]                             68   3e-11
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap...    64   7e-10
gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo sap...    64   7e-10
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ...    62   1e-09
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p...    62   1e-09
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ...    62   1e-09
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP...    62   2e-09
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP...    62   2e-09
gi|73760409 tissue factor pathway inhibitor isoform b precursor ...    62   3e-09
gi|5454114 tissue factor pathway inhibitor isoform a precursor [...    62   3e-09
gi|145309328 papilin [Homo sapiens]                                    61   4e-09
gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]                    60   7e-09
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    58   4e-08
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    58   4e-08
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    58   4e-08
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    57   5e-08
gi|215422388 death-domain associated protein isoform a [Homo sap...    57   5e-08
gi|215422366 death-domain associated protein isoform b [Homo sap...    57   5e-08

>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
           [Homo sapiens]
          Length = 751

 Score = 1522 bits (3941), Expect = 0.0
 Identities = 751/751 (100%), Positives = 751/751 (100%)

Query: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
           MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60

Query: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
           MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120

Query: 121 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT 180
           KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT
Sbjct: 121 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT 180

Query: 181 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF 240
           LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF
Sbjct: 181 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF 240

Query: 241 PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK 300
           PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK
Sbjct: 241 PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK 300

Query: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360

Query: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420
           KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK
Sbjct: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420

Query: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480
           NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ
Sbjct: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480

Query: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
           SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR
Sbjct: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540

Query: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600
           NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH
Sbjct: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600

Query: 601 PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG 660
           PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG
Sbjct: 601 PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG 660

Query: 661 GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD 720
           GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD
Sbjct: 661 GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD 720

Query: 721 PMLTPEERHLNKMQNHGYENPTYKYLEQMQI 751
           PMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 721 PMLTPEERHLNKMQNHGYENPTYKYLEQMQI 751


>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
           [Homo sapiens]
          Length = 763

 Score = 1513 bits (3918), Expect = 0.0
 Identities = 751/763 (98%), Positives = 751/763 (98%), Gaps = 12/763 (1%)

Query: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
           MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60

Query: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
           MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120

Query: 121 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT 180
           KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT
Sbjct: 121 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT 180

Query: 181 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF 240
           LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF
Sbjct: 181 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF 240

Query: 241 PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK 300
           PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK
Sbjct: 241 PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK 300

Query: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360

Query: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420
           KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK
Sbjct: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420

Query: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480
           NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ
Sbjct: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480

Query: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
           SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR
Sbjct: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540

Query: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600
           NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH
Sbjct: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600

Query: 601 PFHPFPALPENE------------GSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD 648
           PFHPFPALPENE            GSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD
Sbjct: 601 PFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD 660

Query: 649 VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ 708
           VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ
Sbjct: 661 VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ 720

Query: 709 YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 751
           YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 721 YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 763


>gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3
           [Homo sapiens]
          Length = 695

 Score = 1205 bits (3117), Expect = 0.0
 Identities = 632/752 (84%), Positives = 645/752 (85%), Gaps = 58/752 (7%)

Query: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
           MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60

Query: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
           MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120

Query: 121 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT 180
           KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT
Sbjct: 121 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT 180

Query: 181 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEF 240
           LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEE                     
Sbjct: 181 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEE--------------------- 219

Query: 241 PTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK 300
                            DE+EEE E+  ED D Y   F   + + E+ TE   D    D+
Sbjct: 220 -----------------DEEEEEEEDEEEDYDVYKSEFP-TEADLEDFTEAAVDEDDEDE 261

Query: 301 EITHDVKAVCSQEAMTGPCRAVMPR-WYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAV 359
           E   +V               V  R +Y+D  KG           G+      ++    V
Sbjct: 262 EEGEEV---------------VEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV 306

Query: 360 CKAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQA 419
               +PPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQA
Sbjct: 307 ---KVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQA 363

Query: 420 KNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAAL 479
           KNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAAL
Sbjct: 364 KNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAAL 423

Query: 480 QSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEER 539
           QSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEER
Sbjct: 424 QSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEER 483

Query: 540 RNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPF 599
           RNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPF
Sbjct: 484 RNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPF 543

Query: 600 HPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERV 659
           HPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERV
Sbjct: 544 HPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERV 603

Query: 660 GGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEV 719
           GGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEV
Sbjct: 604 GGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEV 663

Query: 720 DPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 751
           DPMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 664 DPMLTPEERHLNKMQNHGYENPTYKYLEQMQI 695


>gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform 4
           [Homo sapiens]
          Length = 522

 Score =  766 bits (1978), Expect = 0.0
 Identities = 388/391 (99%), Positives = 390/391 (99%)

Query: 361 KAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 420
           K ++PPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK
Sbjct: 132 KCLVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAK 191

Query: 421 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 480
           NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ
Sbjct: 192 NLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQ 251

Query: 481 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
           SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR
Sbjct: 252 SDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311

Query: 541 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 600
           NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH
Sbjct: 312 NQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH 371

Query: 601 PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG 660
           PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG
Sbjct: 372 PFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVG 431

Query: 661 GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD 720
           GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD
Sbjct: 432 GLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVD 491

Query: 721 PMLTPEERHLNKMQNHGYENPTYKYLEQMQI 751
           PMLTPEERHLNKMQNHGYENPTYKYLEQMQI
Sbjct: 492 PMLTPEERHLNKMQNHGYENPTYKYLEQMQI 522



 Score =  276 bits (706), Expect = 5e-74
 Identities = 135/135 (100%), Positives = 135/135 (100%)

Query: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60
           MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN
Sbjct: 1   MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN 60

Query: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120
           MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK
Sbjct: 61  MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK 120

Query: 121 KQCKSRFVTPFKCLV 135
           KQCKSRFVTPFKCLV
Sbjct: 121 KQCKSRFVTPFKCLV 135


>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
           sapiens]
          Length = 751

 Score =  757 bits (1955), Expect = 0.0
 Identities = 399/765 (52%), Positives = 521/765 (68%), Gaps = 48/765 (6%)

Query: 15  LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDP 74
           L LLLL   TA AL +         NAG    +AEPQIAMFCG+LNMH+N+Q GKW+ DP
Sbjct: 5   LALLLLAAWTARALEVP-----TDGNAGL---LAEPQIAMFCGRLNMHMNVQNGKWDSDP 56

Query: 75  TGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSR--FVTPFK 132
           +GTK+C +TKE +LQYCQE+YPELQITNV+EANQ V+I NWC+R +KQCK+   FV P++
Sbjct: 57  SGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYR 116

Query: 133 CLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGV 192
           CLVGEFVSD LLVP+KC+F H+ERM+VCE H HWHTV KE C  +   L+ YGMLLPCG+
Sbjct: 117 CLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGI 176

Query: 193 DQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDY-DVYKSEFPTEADLEDFTE 251
           D+F G E+VCCP  +   +V   + EED+ +      + DY D  + +    A+ E+  E
Sbjct: 177 DKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAE 236

Query: 252 AAVDE--DDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
              +E  DDED+E+G+EV E+ +  Y+         E  T   +  T + + +   V+ V
Sbjct: 237 VEEEEADDDEDDEDGDEVEEEAEEPYEEAT------ERTTSIATTTTTTTESVEEVVREV 290

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 369
           CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC + IP T  
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAA 350

Query: 370 PTND-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQ 428
            T D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++
Sbjct: 351 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 410

Query: 429 TLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHR 488
            +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  
Sbjct: 411 AVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRH 470

Query: 489 ILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLY 548
           +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY
Sbjct: 471 VFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLY 530

Query: 549 KVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---V 588
            VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V
Sbjct: 531 NVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPV 590

Query: 589 SSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDE 645
           + E S +++ P+H F     PA  ENE   V  +      A+  +         N+  +E
Sbjct: 591 NGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTEE 646

Query: 646 TLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR 705
             +VK M        G E   + +    ED   +  A+IGL+V  V IATVIVI+LVML+
Sbjct: 647 ISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLK 705

Query: 706 KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 750
           K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 706 KKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 750


>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
           sapiens]
          Length = 770

 Score =  746 bits (1925), Expect = 0.0
 Identities = 398/784 (50%), Positives = 522/784 (66%), Gaps = 67/784 (8%)

Query: 15  LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDP 74
           L LLLL   TA AL +         NAG    +AEPQIAMFCG+LNMH+N+Q GKW+ DP
Sbjct: 5   LALLLLAAWTARALEVP-----TDGNAGL---LAEPQIAMFCGRLNMHMNVQNGKWDSDP 56

Query: 75  TGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSR--FVTPFK 132
           +GTK+C +TKE +LQYCQE+YPELQITNV+EANQ V+I NWC+R +KQCK+   FV P++
Sbjct: 57  SGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYR 116

Query: 133 CLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGV 192
           CLVGEFVSD LLVP+KC+F H+ERM+VCE H HWHTV KE C  +   L+ YGMLLPCG+
Sbjct: 117 CLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGI 176

Query: 193 DQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDY-DVYKSEFPTEADLEDFTE 251
           D+F G E+VCCP  +   +V   + EED+ +      + DY D  + +    A+ E+  E
Sbjct: 177 DKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAE 236

Query: 252 AAVDE--DDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
              +E  DDED+E+G+EV E+ +  Y+         E  T   +  T + + +   V+ V
Sbjct: 237 VEEEEADDDEDDEDGDEVEEEAEEPYEEAT------ERTTSIATTTTTTTESVEEVVREV 290

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIP---- 365
           CS++A TGPCRA++ RWYFD+++GKC  F YGGCGGNRNNF++E+YCMAVC + +     
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 350

Query: 366 ----------PTPLPT------NDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVK 409
                     P  LPT      + VD Y ET  D+NEHA FQKAKE+LE +HR RM +V 
Sbjct: 351 KTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVM 410

Query: 410 KEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRR 469
           +EWEEAE QAKNLPKA+++ +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR
Sbjct: 411 REWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRR 470

Query: 470 MALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV 529
           +ALENY+ ALQ+ PPRP  +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQV
Sbjct: 471 LALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQV 530

Query: 530 MTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQR-------ADM---------- 572
           MTHL VI ER NQSLSLLY VP VA+EIQ+E+DELLQ+++       A+M          
Sbjct: 531 MTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGN 590

Query: 573 DQFTASISETPVDVR---VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGA 626
           D    S++ET   V    V+ E S +++ P+H F     PA  ENE   V  +      A
Sbjct: 591 DALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AA 646

Query: 627 EEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGL 686
           +  +         N+  +E  +VK M        G E   + +    ED   +  A+IGL
Sbjct: 647 DRGLTTRPGSGLTNIKTEEISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL 705

Query: 687 LVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYL 746
           +V  V IATVIVI+LVML+K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ 
Sbjct: 706 MVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFF 765

Query: 747 EQMQ 750
           EQMQ
Sbjct: 766 EQMQ 769


>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
           sapiens]
          Length = 714

 Score =  661 bits (1705), Expect = 0.0
 Identities = 353/706 (50%), Positives = 467/706 (66%), Gaps = 59/706 (8%)

Query: 93  EMYPELQITNVMEANQRVSIDNWCRRDKKQCKSR--FVTPFKCLVGEFVSDVLLVPEKCQ 150
           E+YPELQITNV+EANQ V+I NWC+R +KQCK+   FV P++CLVGEFVSD LLVP+KC+
Sbjct: 19  EVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCK 78

Query: 151 FFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIG 210
           F H+ERM+VCE H HWHTV KE C  +   L+ YGMLLPCG+D+F G E+VCCP  +   
Sbjct: 79  FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD 138

Query: 211 SVSKEEEEEDEEEEEEEDEEEDY-DVYKSEFPTEADLEDFTEAAVDE--DDEDEEEGEEV 267
           +V   + EED+ +      + DY D  + +    A+ E+  E   +E  DDED+E+G+EV
Sbjct: 139 NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEV 198

Query: 268 VEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWY 327
            E+ +  Y+         E  T   +  T + + +   V+ VCS++A TGPCRA++ RWY
Sbjct: 199 EEEAEEPYEEAT------ERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWY 252

Query: 328 FDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIP--------------PTPLPT-- 371
           FD+++GKC  F YGGCGGNRNNF++E+YCMAVC + +               P  LPT  
Sbjct: 253 FDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTA 312

Query: 372 ----NDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAER 427
               + VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA++
Sbjct: 313 ASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADK 372

Query: 428 QTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPH 487
           + +IQHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP 
Sbjct: 373 KAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPR 432

Query: 488 RILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLL 547
            +   L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLL
Sbjct: 433 HVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLL 492

Query: 548 YKVPYVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR--- 587
           Y VP VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    
Sbjct: 493 YNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLP 552

Query: 588 VSSEES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVID 644
           V+ E S +++ P+H F     PA  ENE   V  +      A+  +         N+  +
Sbjct: 553 VNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTE 608

Query: 645 ETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVML 704
           E  +VK M        G E   + +    ED   +  A+IGL+V  V IATVIVI+LVML
Sbjct: 609 EISEVK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVML 667

Query: 705 RKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 750
           +K+QY +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 668 KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 713


>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
           sapiens]
          Length = 695

 Score =  638 bits (1646), Expect = 0.0
 Identities = 367/762 (48%), Positives = 468/762 (61%), Gaps = 98/762 (12%)

Query: 15  LLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDP 74
           L LLLL   TA AL +         NAG    +AEPQIAMFCG+LNMH+N+Q GKW+ DP
Sbjct: 5   LALLLLAAWTARALEVP-----TDGNAGL---LAEPQIAMFCGRLNMHMNVQNGKWDSDP 56

Query: 75  TGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSR--FVTPFK 132
           +GTK+C +TKE +LQYCQE+YPELQITNV+EANQ V+I NWC+R +KQCK+   FV P++
Sbjct: 57  SGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYR 116

Query: 133 CLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGV 192
           CLVGEFVSD LLVP+KC+F H+ERM+VCE H HWHTV KE C  +   L+ YGMLLPCG+
Sbjct: 117 CLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGI 176

Query: 193 DQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEA 252
           D+F G E+VCCP             EE +  +  + EE+D DV+     T  D  D +E 
Sbjct: 177 DKFRGVEFVCCPLA-----------EESDNVDSADAEEDDSDVWWGGADT--DYADGSED 223

Query: 253 AVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQ 312
            V E  E+EE  E   E+ D   D   GD+  EE   EP  + T     I          
Sbjct: 224 KVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEE-AEEPYEEATERTTSIATTTTTTTE- 281

Query: 313 EAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTN 372
                             S  + VR                          +P T   T 
Sbjct: 282 ------------------SVEEVVR--------------------------VPTTAASTP 297

Query: 373 D-VDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLI 431
           D VD Y ET  D+NEHA FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++ +I
Sbjct: 298 DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVI 357

Query: 432 QHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQ 491
           QHFQ  V++LE+EAA+E+QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  +  
Sbjct: 358 QHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFN 417

Query: 492 ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVP 551
            L++YVRAE KDR HT++H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY VP
Sbjct: 418 MLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP 477

Query: 552 YVAQEIQEEIDELLQEQR-------ADM----------DQFTASISETPVDVR---VSSE 591
            VA+EIQ+E+DELLQ+++       A+M          D    S++ET   V    V+ E
Sbjct: 478 AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGE 537

Query: 592 ES-EEIPPFHPF--HPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLD 648
            S +++ P+H F     PA  ENE   V  +      A+  +         N+  +E  +
Sbjct: 538 FSLDDLQPWHSFGADSVPANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTEEISE 593

Query: 649 VKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQ 708
           VK M        G E   + +    ED   +  A+IGL+V  V IATVIVI+LVML+K+Q
Sbjct: 594 VK-MDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQ 652

Query: 709 YGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ 750
           Y +I HG+VEVD  +TPEERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 653 YTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQ 694


>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
           sapiens]
          Length = 639

 Score =  553 bits (1426), Expect = e-157
 Identities = 322/684 (47%), Positives = 413/684 (60%), Gaps = 90/684 (13%)

Query: 93  EMYPELQITNVMEANQRVSIDNWCRRDKKQCKSR--FVTPFKCLVGEFVSDVLLVPEKCQ 150
           E+YPELQITNV+EANQ V+I NWC+R +KQCK+   FV P++CLVGEFVSD LLVP+KC+
Sbjct: 19  EVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCK 78

Query: 151 FFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIG 210
           F H+ERM+VCE H HWHTV KE C  +   L+ YGMLLPCG+D+F G E+VCCP      
Sbjct: 79  FLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLA---- 134

Query: 211 SVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVED 270
                  EE +  +  + EE+D DV+     T  D  D +E  V E  E+EE  E   E+
Sbjct: 135 -------EESDNVDSADAEEDDSDVWWGGADT--DYADGSEDKVVEVAEEEEVAEVEEEE 185

Query: 271 RDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDL 330
            D   D   GD+  EE   EP  + T     I                            
Sbjct: 186 ADDDEDDEDGDEVEEE-AEEPYEEATERTTSIATTTTTTTE------------------- 225

Query: 331 SKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTND-VDVYFETSADDNEHAR 389
           S  + VR                          +P T   T D VD Y ET  D+NEHA 
Sbjct: 226 SVEEVVR--------------------------VPTTAASTPDAVDKYLETPGDENEHAH 259

Query: 390 FQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEK 449
           FQKAKE+LE +HR RM +V +EWEEAE QAKNLPKA+++ +IQHFQ  V++LE+EAA+E+
Sbjct: 260 FQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANER 319

Query: 450 QQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIR 509
           QQLVETH+ARVEAMLNDRRR+ALENY+ ALQ+ PPRP  +   L++YVRAE KDR HT++
Sbjct: 320 QQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLK 379

Query: 510 HYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQR 569
           H++HV  VDP+KAAQ++SQVMTHL VI ER NQSLSLLY VP VA+EIQ+E+DELLQ+++
Sbjct: 380 HFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQ 439

Query: 570 -------ADM----------DQFTASISETPVDVR---VSSEES-EEIPPFHPF--HPFP 606
                  A+M          D    S++ET   V    V+ E S +++ P+H F     P
Sbjct: 440 NYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVP 499

Query: 607 ALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEER 666
           A  ENE   V  +      A+  +         N+  +E  +VK M        G E   
Sbjct: 500 ANTENEVEPVDARP----AADRGLTTRPGSGLTNIKTEEISEVK-MDAEFRHDSGYEVHH 554

Query: 667 ESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPE 726
           + +    ED   +  A+IGL+V  V IATVIVI+LVML+K+QY +I HG+VEVD  +TPE
Sbjct: 555 QKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPE 614

Query: 727 ERHLNKMQNHGYENPTYKYLEQMQ 750
           ERHL+KMQ +GYENPTYK+ EQMQ
Sbjct: 615 ERHLSKMQQNGYENPTYKFFEQMQ 638


>gi|4885065 amyloid precursor-like protein 1 isoform 2 precursor
           [Homo sapiens]
          Length = 650

 Score =  302 bits (773), Expect = 9e-82
 Identities = 170/386 (44%), Positives = 239/386 (61%), Gaps = 22/386 (5%)

Query: 364 IPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP 423
           + PTP PT+ VD+YF    + +EH  F +AK  LE R   +++ V +EW  A+ Q+KNLP
Sbjct: 284 VTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLP 343

Query: 424 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 483
           KA+RQ L +HFQ++++ LE++ + E+Q+LVETH  RV A++ND+RR ALE +LAALQ+DP
Sbjct: 344 KADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADP 403

Query: 484 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 543
           P+  R+L ALRRY+RAE K++ HT+RHYQHV AVDPEKA QM+ QV THL VIEER NQS
Sbjct: 404 PQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQS 463

Query: 544 LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH 603
           L LL + P++AQE++ +I ELL  +     +      E P     S ++    PP     
Sbjct: 464 LGLLDQNPHLAQELRPQIQELLHSEHLGPSEL-----EAPAPGGSSEDKGGLQPPDSKDD 518

Query: 604 PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE 663
               LP+    G  EQD            S  K   N +      V   +         E
Sbjct: 519 TPMTLPK----GSTEQDAA----------SPEKEKMNPLEQYERKVNASVPRGFPFHSSE 564

Query: 664 EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVML-RKRQYGTISHGIVEVDPM 722
            +R+ + P      +S  A+ GLL++     ++IV+S+++L RK+ YG ISHG+VEVDPM
Sbjct: 565 IQRDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPM 622

Query: 723 LTPEERHLNKMQNHGYENPTYKYLEQ 748
           LT EE+ L ++Q HGYENPTY++LE+
Sbjct: 623 LTLEEQQLRELQRHGYENPTYRFLEE 648



 Score =  188 bits (478), Expect = 1e-47
 Identities = 104/257 (40%), Positives = 143/257 (55%), Gaps = 23/257 (8%)

Query: 15  LLLLLLVGLTAPAL-ALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPD 73
           L LLLL+    PA+ +LAG       + G   A    Q+A  CG+L +H +++TG+WEPD
Sbjct: 24  LPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPD 77

Query: 74  PTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKK-QCKSRF--VTP 130
           P  ++ C    + VL+YC++MYPELQI  V +A Q + ++ WC   +   C      V P
Sbjct: 78  PQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVP 137

Query: 131 FKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPC 190
           F+CL GEFVS+ LLVPE C+F H+ERM+ CE+    H   +EAC +QG+ L+  GMLLPC
Sbjct: 138 FRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPC 197

Query: 191 GVDQFHGTEYVCC-------PQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTE 243
           G D+F G EYVCC       P    +G  S          E  EDEEE+       FP  
Sbjct: 198 GSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEE-----ESFPQP 252

Query: 244 ADLEDFTEAAVDEDDED 260
            D + F E    E++E+
Sbjct: 253 VD-DYFVEPPQAEEEEE 268


>gi|67782338 amyloid precursor-like protein 1 isoform 1 precursor
           [Homo sapiens]
          Length = 651

 Score =  301 bits (771), Expect = 1e-81
 Identities = 170/386 (44%), Positives = 238/386 (61%), Gaps = 21/386 (5%)

Query: 364 IPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLP 423
           + PTP PT+ VD+YF    + +EH  F +AK  LE R   +++ V +EW  A+ Q+KNLP
Sbjct: 284 VTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLP 343

Query: 424 KAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDP 483
           KA+RQ L +HFQ++++ LE++ + E+Q+LVETH  RV A++ND+RR ALE +LAALQ+DP
Sbjct: 344 KADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADP 403

Query: 484 PRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQS 543
           P+  R+L ALRRY+RAE K++ HT+RHYQHV AVDPEKA QM+ QV THL VIEER NQS
Sbjct: 404 PQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQS 463

Query: 544 LSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFH 603
           L LL + P++AQE++ +I ELL  +     +  A           SSE+   + P  P  
Sbjct: 464 LGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGG------SSEDKGGLQP--PDS 515

Query: 604 PFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLE 663
                P     G  EQD            S  K   N +      V   +         E
Sbjct: 516 KDADTPMTLPKGSTEQDAA----------SPEKEKMNPLEQYERKVNASVPRGFPFHSSE 565

Query: 664 EERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVML-RKRQYGTISHGIVEVDPM 722
            +R+ + P      +S  A+ GLL++     ++IV+S+++L RK+ YG ISHG+VEVDPM
Sbjct: 566 IQRDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPM 623

Query: 723 LTPEERHLNKMQNHGYENPTYKYLEQ 748
           LT EE+ L ++Q HGYENPTY++LE+
Sbjct: 624 LTLEEQQLRELQRHGYENPTYRFLEE 649



 Score =  188 bits (478), Expect = 1e-47
 Identities = 104/257 (40%), Positives = 143/257 (55%), Gaps = 23/257 (8%)

Query: 15  LLLLLLVGLTAPAL-ALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPD 73
           L LLLL+    PA+ +LAG       + G   A    Q+A  CG+L +H +++TG+WEPD
Sbjct: 24  LPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPD 77

Query: 74  PTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKK-QCKSRF--VTP 130
           P  ++ C    + VL+YC++MYPELQI  V +A Q + ++ WC   +   C      V P
Sbjct: 78  PQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVP 137

Query: 131 FKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPC 190
           F+CL GEFVS+ LLVPE C+F H+ERM+ CE+    H   +EAC +QG+ L+  GMLLPC
Sbjct: 138 FRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPC 197

Query: 191 GVDQFHGTEYVCC-------PQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTE 243
           G D+F G EYVCC       P    +G  S          E  EDEEE+       FP  
Sbjct: 198 GSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEE-----ESFPQP 252

Query: 244 ADLEDFTEAAVDEDDED 260
            D + F E    E++E+
Sbjct: 253 VD-DYFVEPPQAEEEEE 268


>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
           sapiens]
          Length = 252

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 34/83 (40%), Positives = 46/83 (55%)

Query: 288 PTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNR 347
           P+ P    +        + +  C+  A+TGPCRA  PRWYFD+ +  C  FIYGGC GN+
Sbjct: 111 PSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNK 170

Query: 348 NNFESEDYCMAVCKAMIPPTPLP 370
           N++ SE+ CM  C       PLP
Sbjct: 171 NSYRSEEACMLRCFRQQENPPLP 193



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 22/51 (43%), Positives = 34/51 (66%)

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           C    + G CRA MPRW+++++ G C  F+YGGC GN NN+ +++ C+  C
Sbjct: 38  CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88


>gi|28212222 WFIKKN2 protein [Homo sapiens]
          Length = 576

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 27/53 (50%), Positives = 34/53 (64%)

Query: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           A CS  A+ GPC+A  PRW ++   G+C  F+YGGC GN NNFES + C   C
Sbjct: 384 AACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 18/53 (33%), Positives = 26/53 (49%)

Query: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           A C +   +  C     RW+FD     C+ F +G C  N N+FE+ + CM  C
Sbjct: 326 AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378


>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
           sapiens]
          Length = 352

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 28/53 (52%), Positives = 31/53 (58%)

Query: 308 AVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           A C+   + GPCRA +  W FD  KGKCV F YGGC GN N F SE  C   C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 290 EPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNN 349
           E GS G     E+T    + C      GPC  +  R++++ +   C  F YGGC GN NN
Sbjct: 212 EEGSGGGQLVTEVTKKEDS-CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNN 270

Query: 350 FESEDYCMAVCKAM 363
           F +E  C+  C+ +
Sbjct: 271 FVTEKECLQTCRTV 284


>gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo
           sapiens]
          Length = 89

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 25/53 (47%), Positives = 32/53 (60%)

Query: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
           VC+     GPC+  M RW+F+   G+C  F YGGCGGN NNF  ++ C   CK
Sbjct: 35  VCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87


>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
           precursor [Homo sapiens]
          Length = 513

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 25/57 (43%), Positives = 33/57 (57%)

Query: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
           K  C     TG C+  +PRWY++     C RF YGGC GN+NNFE E  C+  C+ +
Sbjct: 372 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 428



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 6/118 (5%)

Query: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
           T+  V+  D ++ E   + E    +  T    D+ E+  T   +   +S K+ T D    
Sbjct: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPT 367
           C      G CR   PRWY+D ++  C  F+YGGC GN+NN+  E+ C+  C+ +  P+
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307


>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
           precursor [Homo sapiens]
          Length = 513

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 25/57 (43%), Positives = 33/57 (57%)

Query: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
           K  C     TG C+  +PRWY++     C RF YGGC GN+NNFE E  C+  C+ +
Sbjct: 372 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 428



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 6/118 (5%)

Query: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
           T+  V+  D ++ E   + E    +  T    D+ E+  T   +   +S K+ T D    
Sbjct: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPT 367
           C      G CR   PRWY+D ++  C  F+YGGC GN+NN+  E+ C+  C+ +  P+
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307


>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
           precursor [Homo sapiens]
          Length = 529

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 25/57 (43%), Positives = 33/57 (57%)

Query: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
           K  C     TG C+  +PRWY++     C RF YGGC GN+NNFE E  C+  C+ +
Sbjct: 388 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 444



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 6/114 (5%)

Query: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
           T+  V+  D ++ E   + E    +  T    D+ E+  T   +   +S K+ T D    
Sbjct: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363
           C      G CR   PRWY+D ++  C  F+YGGC GN+NN+  E+ C+  C+ +
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGV 303


>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
           domains 1 isoform 2 [Homo sapiens]
          Length = 117

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 24/53 (45%), Positives = 30/53 (56%)

Query: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
           VC     TGPC A    W++D     C  F+YGGC GN NNF+S+  C+  CK
Sbjct: 60  VCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 112


>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
           domains 1 isoform 1 precursor [Homo sapiens]
          Length = 133

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 24/53 (45%), Positives = 30/53 (56%)

Query: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
           VC     TGPC A    W++D     C  F+YGGC GN NNF+S+  C+  CK
Sbjct: 76  VCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 128


>gi|73760409 tissue factor pathway inhibitor isoform b precursor
           [Homo sapiens]
          Length = 251

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 24/51 (47%), Positives = 36/51 (70%)

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           C+ +A  GPC+A+M R++F++   +C  FIYGGC GN+N FES + C  +C
Sbjct: 54  CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 21/52 (40%), Positives = 31/52 (59%)

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
           C  E   G CR  + R++++    +C RF YGGC GN NNFE+ + C  +C+
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICE 176


>gi|5454114 tissue factor pathway inhibitor isoform a precursor
           [Homo sapiens]
          Length = 304

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 24/51 (47%), Positives = 36/51 (70%)

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
           C+ +A  GPC+A+M R++F++   +C  FIYGGC GN+N FES + C  +C
Sbjct: 54  CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 25/52 (48%), Positives = 30/52 (57%)

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
           C   A  G CRA   R+Y++   GKC  F Y GCGGN NNF S+  C+  CK
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 21/52 (40%), Positives = 31/52 (59%)

Query: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
           C  E   G CR  + R++++    +C RF YGGC GN NNFE+ + C  +C+
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICE 176


>gi|145309328 papilin [Homo sapiens]
          Length = 1251

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 30/70 (42%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 303 THDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
           +H     C   +  G C     RWYF  S G+C RF YGGC GN NNF SE  CM+ C+ 
Sbjct: 720 SHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQG 779

Query: 363 MI--PPTPLP 370
            +  P  P P
Sbjct: 780 SLHGPRRPQP 789


>gi|7662316 HIV-1 Vpr binding protein [Homo sapiens]
          Length = 1507

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 7/95 (7%)

Query: 215  EEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYY 274
            E+EEED+EEEE+E+E++D D   ++   E D +   EA ++EDD +E  GE+   D    
Sbjct: 1398 EDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDND---- 1453

Query: 275  YDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309
               F   D    N  E G DG   D +   +V+ +
Sbjct: 1454 ---FSPSDEELANLLEEGEDGEDEDSDADEEVELI 1485



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 28/98 (28%)

Query: 212  VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVE-- 269
            V ++   EDE+EEE+++EEE                        E+++D+E+ ++  +  
Sbjct: 1389 VGRQRLAEDEDEEEDQEEEEQ-----------------------EEEDDDEDDDDTDDLD 1425

Query: 270  --DRDYYYDTFKGDDYNEENPTEPG-SDGTMSDKEITH 304
              D D   +    +D N EN  E G +D + SD+E+ +
Sbjct: 1426 ELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELAN 1463


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 23/56 (41%), Positives = 31/56 (55%)

Query: 309  VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
            +C      G CR  + +WY+D +   C RF YGGCGGN N F S+  C  VC  ++
Sbjct: 2905 ICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVL 2960


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 23/56 (41%), Positives = 31/56 (55%)

Query: 309  VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
            +C      G CR  + +WY+D +   C RF YGGCGGN N F S+  C  VC  ++
Sbjct: 3111 ICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVL 3166


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 23/56 (41%), Positives = 31/56 (55%)

Query: 309  VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
            +C      G CR  + +WY+D +   C RF YGGCGGN N F S+  C  VC  ++
Sbjct: 2504 ICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVL 2559


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 36/99 (36%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 203 CPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEE 262
           CP      +  +++EE DEEEEEEE+EEE+      E   E DLE   E    EDDE+E+
Sbjct: 427 CPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEE---EEDLEQMQEG--QEDDEEED 481

Query: 263 EGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKE 301
           E EE    +D           + E   EPG   + S  E
Sbjct: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGE 520


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 36/99 (36%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 203 CPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEE 262
           CP      +  +++EE DEEEEEEE+EEE+      E   E DLE   E    EDDE+E+
Sbjct: 427 CPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEE---EEDLEQMQEG--QEDDEEED 481

Query: 263 EGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKE 301
           E EE    +D           + E   EPG   + S  E
Sbjct: 482 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGE 520


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 36/99 (36%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 203 CPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEE 262
           CP      +  +++EE DEEEEEEE+EEE+      E   E DLE   E    EDDE+E+
Sbjct: 439 CPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEE---EEDLEQMQEG--QEDDEEED 493

Query: 263 EGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKE 301
           E EE    +D           + E   EPG   + S  E
Sbjct: 494 EEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGE 532


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,541,141
Number of Sequences: 37866
Number of extensions: 1547870
Number of successful extensions: 34527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 550
Number of HSP's successfully gapped in prelim test: 423
Number of HSP's that attempted gapping in prelim test: 15592
Number of HSP's gapped (non-prelim): 8558
length of query: 751
length of database: 18,247,518
effective HSP length: 110
effective length of query: 641
effective length of database: 14,082,258
effective search space: 9026727378
effective search space used: 9026727378
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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