Guide to the Human Genome
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Name: SPINT1 Sequence: fasta or formatted (529aa) NCBI GI: 32313599
Description:

serine peptidase inhibitor, Kunitz type 1 isoform 1 precursor

Referenced in:

Protease Inhibitors

Other entries for this name:
alt prot [513aa] serine peptidase inhibitor, Kunitz type 1 isoform 2 precursor
alt prot [513aa] serine peptidase inhibitor, Kunitz type 1 isoform 2 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         36           2
 C cysteine            5.9         31           2
 D aspartate           5.1         27           2
 E glutamate           6.0         32           3
 F phenylalanine       4.5         24           2
 G glycine             8.3         44           2
 H histidine           2.3         12           4
 I isoleucine          3.2         17           1
 K lysine              3.4         18           2
 L leucine             7.9         42           2
 M methionine          0.8          4           1
 N asparagine          4.3         23           2
 P proline             7.2         38           3
 Q glutamine           4.2         22           2
 R arginine            6.2         33           2
 S serine              5.7         30           2
 T threonine           7.0         37           2
 V valine              6.6         35           4
 W tryptophan          1.3          7           1
 Y tyrosine            3.2         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   serine peptidase inhibitor, Kunitz type 1 isoform 1 ... 
SPINT1                0.961   serine peptidase inhibitor, Kunitz type 1 isoform 2 ...
SPINT1                0.961   serine peptidase inhibitor, Kunitz type 1 isoform 2 p...
SPINT2                0.084   serine protease inhibitor, Kunitz type, 2 
LRP11                 0.074   low density lipoprotein receptor-related protein 11...
TFPI2                 0.064   tissue factor pathway inhibitor 2 
TFPI                  0.061   tissue factor pathway inhibitor isoform a precursor [...
AMBP                  0.036   alpha-1-microglobulin/bikunin preproprotein 
APP                   0.035   amyloid beta A4 protein isoform b precursor 
APP                   0.034   amyloid beta A4 protein isoform a precursor 
APP                   0.034   amyloid beta A4 protein isoform f precursor 
APLP2                 0.034   amyloid beta (A4) precursor-like protein 2 isoform ...
APLP2                 0.034   amyloid beta (A4) precursor-like protein 2 isoform 1 ...
COL6A3                0.033   alpha 3 type VI collagen isoform 5 precursor 
COL6A3                0.033   alpha 3 type VI collagen isoform 1 precursor 
COL6A3                0.033   alpha 3 type VI collagen isoform 4 precursor 
PAPLN                 0.032   papilin 
TFPI                  0.032   tissue factor pathway inhibitor isoform b precursor ...
WFIKKN1               0.031   WAP, follistatin/kazal, immunoglobulin, kunitz and n...
WFIKKN2               0.030   WFIKKN2 protein 
SPINLW1               0.029   serine peptidase inhibitor-like, with Kunitz and WAP...
SPINLW1               0.029   serine peptidase inhibitor-like, with Kunitz and WAP...
COL28A1               0.026   collagen, type XXVIII precursor 
SORL1                 0.024   sortilin-related receptor containing LDLR class A rep...
VLDLR                 0.023   very low density lipoprotein receptor isoform b [Hom...
VLDLR                 0.023   very low density lipoprotein receptor isoform a [Hom...
SPINT3                0.023   serine protease inhibitor, Kunitz type, 3 
WFDC8                 0.022   WAP four-disulfide core domain 8 precursor 
WFDC8                 0.022   WAP four-disulfide core domain 8 precursor 
LRP5                  0.022   low density lipoprotein receptor-related protein 5 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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