Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21389511
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389511 zinc finger, matrin type 2 [Homo sapiens]
(199 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389511 zinc finger, matrin type 2 [Homo sapiens] 404 e-113
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 49 2e-06
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 49 2e-06
gi|92859701 myosin VI [Homo sapiens] 48 5e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 47 1e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 47 1e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 2e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 46 2e-05
gi|50962882 G patch domain containing 8 [Homo sapiens] 46 2e-05
gi|52426743 cisplatin resistance-associated overexpressed protei... 45 3e-05
gi|19923485 cisplatin resistance-associated overexpressed protei... 45 3e-05
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 43 2e-04
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 43 2e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 43 2e-04
gi|148746195 trichohyalin [Homo sapiens] 43 2e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 3e-04
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap... 42 3e-04
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 42 3e-04
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 42 3e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 42 3e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 42 3e-04
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 42 3e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 42 3e-04
gi|154354979 myosin X [Homo sapiens] 42 3e-04
gi|62244004 modulator of estrogen induced transcription isoform ... 42 3e-04
gi|63176611 modulator of estrogen induced transcription isoform ... 42 3e-04
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 42 3e-04
gi|161702986 ezrin [Homo sapiens] 42 4e-04
gi|21614499 ezrin [Homo sapiens] 42 4e-04
>gi|21389511 zinc finger, matrin type 2 [Homo sapiens]
Length = 199
Score = 404 bits (1037), Expect = e-113
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MASGSGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLES 60
MASGSGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLES
Sbjct: 1 MASGSGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLES 60
Query: 61 KLGKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLD 120
KLGKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLD
Sbjct: 61 KLGKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLD 120
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED
Sbjct: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
Query: 181 DEMAAVMGFSGFGSTKKSY 199
DEMAAVMGFSGFGSTKKSY
Sbjct: 181 DEMAAVMGFSGFGSTKKSY 199
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 49.3 bits (116), Expect = 2e-06
Identities = 23/65 (35%), Positives = 43/65 (66%)
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
KKR E +K+K E+K++ EE++K E ++K + KK+ Q+E++++ EE ++++E
Sbjct: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE 116
Query: 183 MAAVM 187
AA M
Sbjct: 117 AAAQM 121
Score = 36.6 bits (83), Expect = 0.014
Identities = 18/62 (29%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
+V K E KK++E+ ++ + +ER K+ EE+ KA+ K+K++E+K++ +E+ +++
Sbjct: 48 EVSKAPEDKKKRLEDDKRKKEDKERKKK-DEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
Query: 181 DE 182
++
Sbjct: 107 EQ 108
Score = 35.4 bits (80), Expect = 0.032
Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREE----EEKAKAYKKEKQKEKKRR 170
+R D+ +K+ + K K EE+ K + EE+ K EE EE+AK ++E+ + +
Sbjct: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
Query: 171 AEEDLTFEED 180
EE + ++
Sbjct: 124 KEESIQLHQE 133
Score = 32.7 bits (73), Expect = 0.21
Identities = 16/69 (23%), Positives = 35/69 (50%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
KK + + ++ ++ KK E +KK EE+ K EE +++E+EE + +++
Sbjct: 74 KKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE 133
Query: 162 EKQKEKKRR 170
++ R+
Sbjct: 134 AWERHHLRK 142
Score = 32.3 bits (72), Expect = 0.27
Identities = 19/68 (27%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
ER T+ K+R + + K +K+ E++ K L +++ K + +++K+ E+K +AEE+
Sbjct: 27 ERRTVSS-KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEE 85
Query: 175 LTFEEDDE 182
+E++E
Sbjct: 86 SKKKEEEE 93
Score = 32.3 bits (72), Expect = 0.27
Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 7/66 (10%)
Query: 115 ERSTLDQVK-KRFEVNKKKMEEKQKDYDFEERMKE------LREEEEKAKAYKKEKQKEK 167
ER D+ K K E +KKK EE++K + EER K+ +EEE A+ +KE+ +
Sbjct: 71 ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQL 130
Query: 168 KRRAEE 173
+ A E
Sbjct: 131 HQEAWE 136
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 49.3 bits (116), Expect = 2e-06
Identities = 23/65 (35%), Positives = 43/65 (66%)
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
KKR E +K+K E+K++ EE++K E ++K + KK+ Q+E++++ EE ++++E
Sbjct: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE 116
Query: 183 MAAVM 187
AA M
Sbjct: 117 AAAQM 121
Score = 36.6 bits (83), Expect = 0.014
Identities = 18/62 (29%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
+V K E KK++E+ ++ + +ER K+ EE+ KA+ K+K++E+K++ +E+ +++
Sbjct: 48 EVSKAPEDKKKRLEDDKRKKEDKERKKK-DEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
Query: 181 DE 182
++
Sbjct: 107 EQ 108
Score = 35.4 bits (80), Expect = 0.032
Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREE----EEKAKAYKKEKQKEKKRR 170
+R D+ +K+ + K K EE+ K + EE+ K EE EE+AK ++E+ + +
Sbjct: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
Query: 171 AEEDLTFEED 180
EE + ++
Sbjct: 124 KEESIQLHQE 133
Score = 32.7 bits (73), Expect = 0.21
Identities = 16/69 (23%), Positives = 35/69 (50%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
KK + + ++ ++ KK E +KK EE+ K EE +++E+EE + +++
Sbjct: 74 KKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE 133
Query: 162 EKQKEKKRR 170
++ R+
Sbjct: 134 AWERHHLRK 142
Score = 32.3 bits (72), Expect = 0.27
Identities = 19/68 (27%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
ER T+ K+R + + K +K+ E++ K L +++ K + +++K+ E+K +AEE+
Sbjct: 27 ERRTVSS-KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEE 85
Query: 175 LTFEEDDE 182
+E++E
Sbjct: 86 SKKKEEEE 93
Score = 32.3 bits (72), Expect = 0.27
Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 7/66 (10%)
Query: 115 ERSTLDQVK-KRFEVNKKKMEEKQKDYDFEERMKE------LREEEEKAKAYKKEKQKEK 167
ER D+ K K E +KKK EE++K + EER K+ +EEE A+ +KE+ +
Sbjct: 71 ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQL 130
Query: 168 KRRAEE 173
+ A E
Sbjct: 131 HQEAWE 136
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 48.1 bits (113), Expect = 5e-06
Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 13/154 (8%)
Query: 36 KDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGGYYCNVCDCVVKDSINF 95
KDGKP + +++ + +D K+ ++T+ Q E D +VK S
Sbjct: 861 KDGKPEM---NKQIKNLEISIDTLMAKIKSTMMTQEQIQKEY--------DALVKSSEEL 909
Query: 96 LDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKM--EEKQKDYDFEERMKELREEE 153
L + KK Q +R + +++ +KR E ++K+ EE+++ E K +EEE
Sbjct: 910 LSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEE 969
Query: 154 EKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVM 187
E+ K EK+ + + A+ EE+ + AV+
Sbjct: 970 ERKKREDDEKRIQAEVEAQLARQKEEESQQQAVL 1003
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 46.6 bits (109), Expect = 1e-05
Identities = 45/172 (26%), Positives = 77/172 (44%), Gaps = 18/172 (10%)
Query: 6 GTKNLDFRRKWDKDEYEKLAEKRLTE---EREKKDGKPVQPVKRELLRHRDYKVDLESKL 62
G K + RK ++ E EK +R E ER KK+ K + K+E + + + E+K
Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERGKKEKKGER--KKEERERKKRRREKENKE 108
Query: 63 GKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQV 122
G+ K + E G K+ +K +R ER ++
Sbjct: 109 GEEKEKRKKKEKKERGR--------TSKEGKE-----RERKEERKREERKERERKKEERE 155
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
K+R +KK E KQ EER ++ R+E +K + +KE++KE++R+ +
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/53 (33%), Positives = 32/53 (60%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEE 173
+++ R E K++ E++K+ E+ K RE+E K + KKEK+ E+K+ E
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Score = 35.8 bits (81), Expect = 0.025
Identities = 20/82 (24%), Positives = 44/82 (53%)
Query: 101 GKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYK 160
GKK + + R ER + +++ ++ +EK+ + EER ++ R E++ K +
Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE 110
Query: 161 KEKQKEKKRRAEEDLTFEEDDE 182
++++++KK + E T +E E
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKE 132
Score = 33.9 bits (76), Expect = 0.094
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQ------KDYDFEERMKELREEEEK 155
KK +R R +R + K+ E K+K +EK+ K+ ER +E + EE K
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 156 AKAYKKEKQ------KEKKRRAEEDLTFEEDD 181
+ KKE++ KE+K+R + + +E++
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEE 177
Score = 33.5 bits (75), Expect = 0.12
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E+ + K+R +K+ E ++K EER +E R+E E+ K ++++++ K+R+ E
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERK----EERKREERKERERKKEEREKERERKERKKRER 168
Query: 175 LTFEEDDE 182
E +E
Sbjct: 169 KQVGEKEE 176
Score = 32.3 bits (72), Expect = 0.27
Identities = 21/81 (25%), Positives = 38/81 (46%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
++ +R R + ++ KK + +KK E ++K E+ KE E+E++ K KK
Sbjct: 62 ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121
Query: 162 EKQKEKKRRAEEDLTFEEDDE 182
E+ + K E + E E
Sbjct: 122 ERGRTSKEGKERERKEERKRE 142
Score = 31.6 bits (70), Expect = 0.47
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 101 GKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYK 160
GKK ++ G + ER ++ K+R E K+ EEK+K E++ + +E K + K
Sbjct: 82 GKKEKK--GERKKEER---ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERK 136
Query: 161 KE-KQKEKKRRAEEDLTFEEDDE 182
+E K++E+K R + E++ E
Sbjct: 137 EERKREERKERERKKEEREKERE 159
Score = 31.2 bits (69), Expect = 0.61
Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 11/79 (13%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVN----KKKMEEKQKDYDFEERMKELREEEEKAK 157
K+ ++ +G + + +K+ E N KK+ E K++ ER KE +++EE+ K
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER----RERKKERKKKEERKK 220
Query: 158 AYKKEKQ---KEKKRRAEE 173
+K++Q +EK+R E
Sbjct: 221 ERQKDRQTNWREKERGKRE 239
Score = 30.8 bits (68), Expect = 0.79
Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 11/67 (16%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELR---EEEEKAKA 158
KK +RN R ER + ++R E ++K E K+K+ +ER K+ + E+E+ K
Sbjct: 187 KKRERN-----RKERK---KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
Query: 159 YKKEKQK 165
+KE++K
Sbjct: 239 ERKERKK 245
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 46.6 bits (109), Expect = 1e-05
Identities = 23/81 (28%), Positives = 47/81 (58%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
KK ++ E ++ +++ K+K +EK+K+ + +++ KE + +EK + KK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 162 EKQKEKKRRAEEDLTFEEDDE 182
K+K KK++ EE+ EE++E
Sbjct: 62 RKRKRKKKKEEEEREEEEEEE 82
Score = 45.4 bits (106), Expect = 3e-05
Identities = 21/55 (38%), Positives = 40/55 (72%), Gaps = 1/55 (1%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
++ KKR KKK EE++++ + EE +E +EEEEK + +++K+K+++R+ EE+
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEE-KEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 45.1 bits (105), Expect = 4e-05
Identities = 29/85 (34%), Positives = 49/85 (57%), Gaps = 4/85 (4%)
Query: 102 KKHQRNLGMSMRVERSTLDQVK--KRFEVNKKKMEEKQKDYDFEE--RMKELREEEEKAK 157
KK ++ + E + ++ K KR E K+K +EK+K +E + KE EEE+K K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 158 AYKKEKQKEKKRRAEEDLTFEEDDE 182
+K+K++E++R EE+ EE +E
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEE 88
Score = 41.2 bits (95), Expect = 6e-04
Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+K +R + + T + +K E K+K + K+K + E +E EEEEK + K+
Sbjct: 33 RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92
Query: 162 E----KQKEKKRRAEED 174
E K+K+K+RR EE+
Sbjct: 93 EGRRRKKKKKRRRKEEE 109
Score = 40.0 bits (92), Expect = 0.001
Identities = 17/60 (28%), Positives = 41/60 (68%)
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
K++ + +K+ E+K+K + E+R ++ EE+++ + KK+K++E++ EE+ E+++E
Sbjct: 30 KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89
Score = 38.1 bits (87), Expect = 0.005
Identities = 19/59 (32%), Positives = 36/59 (61%)
Query: 124 KRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
K+ + KK+ EE ++ + EE ++ + +EK K +KEK+K+KK + E +E++E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.8 bits (107), Expect = 2e-05
Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 19/170 (11%)
Query: 16 WDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKV-DLESKLGKTIVITKTTPQ 74
W+++E E ++RL E++EK + + E + ++ K+ D E G+ + +
Sbjct: 481 WEQEEKE-WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 75 SEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKME 134
E +D + + + Q+ R+E+ T +Q KK ++ +K E
Sbjct: 540 REQ------------EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 135 EKQKDYDFEERMKELREEEEKAKAY-KKEKQKEKKRRAEEDLTFEEDDEM 183
E++ ER K++REEEE + +K +++E+K + +E+ +E++++M
Sbjct: 588 EER----MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Score = 43.1 bits (100), Expect = 2e-04
Identities = 23/92 (25%), Positives = 50/92 (54%), Gaps = 10/92 (10%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE----------LRE 151
+K R MR + + + +R +++M E++K ++ E+M+E R+
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD 441
Query: 152 EEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
+EEK + ++ +++EKK R EE+ E++++M
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMREQEEKM 473
Score = 42.0 bits (97), Expect = 3e-04
Identities = 24/73 (32%), Positives = 47/73 (64%), Gaps = 8/73 (10%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEE--KAKAYKKEKQKEKKRR 170
++E+ T +Q KK ++ K + EE + ER K++REEEE + + K ++Q+EK +
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMR-----EREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 171 AEEDLTFEEDDEM 183
EE++ +E++++M
Sbjct: 746 QEEEM-WEQEEKM 757
Score = 40.0 bits (92), Expect = 0.001
Identities = 22/87 (25%), Positives = 49/87 (56%), Gaps = 5/87 (5%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE-----LREEEEKA 156
+K R +R + L + K+ E ++ E+++K ++ EE+M+E R+EE
Sbjct: 320 EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 157 KAYKKEKQKEKKRRAEEDLTFEEDDEM 183
+ K+ +++E+K R +E+ +E+D+ +
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERL 406
Score = 38.9 bits (89), Expect = 0.003
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 9/71 (12%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
MR E+ +Q KK + +K EE++ ER K++REEEE + +Q+EK ++
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEER----IREREKKMREEEETMR-----EQEEKMQKQ 476
Query: 172 EEDLTFEEDDE 182
EE++ +E+ E
Sbjct: 477 EENMWEQEEKE 487
Score = 38.5 bits (88), Expect = 0.004
Identities = 21/77 (27%), Positives = 43/77 (55%), Gaps = 8/77 (10%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREE--------EEKAKAYKKEKQKE 166
E +Q +K +E +K E+++K ++ EE+M E E+ E+K K ++ EK +E
Sbjct: 616 EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE 675
Query: 167 KKRRAEEDLTFEEDDEM 183
+++ E++ E ++M
Sbjct: 676 QEKMQEQEEKIWEQEKM 692
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 9/71 (12%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKE----LREEEEKAKAYKK-----EKQKEKKRRA 171
Q ++ +E K+ E++QK D EERM E LRE+EE+ + +K EK +E+K+
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ 433
Query: 172 EEDLTFEEDDE 182
E++ + +E
Sbjct: 434 EQEKKTRDQEE 444
Score = 36.6 bits (83), Expect = 0.014
Identities = 20/82 (24%), Positives = 47/82 (57%), Gaps = 3/82 (3%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
KK ++ R E +Q K E +K ++++ E+ KELRE+E++ + K+
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR---LREQEKELREQEKELREQKE 342
Query: 162 EKQKEKKRRAEEDLTFEEDDEM 183
+++E++ + +E+ +E++++M
Sbjct: 343 LREQEEQMQEQEEKMWEQEEKM 364
Score = 36.6 bits (83), Expect = 0.014
Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERM----KELREEEEKAKAYKKEKQKEKKRR 170
E +Q +K +E +K E+++K + EER+ K++RE+E+K + ++ ++ +R
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 171 AEEDLTFEEDDEM 183
E++ E ++M
Sbjct: 407 REKEERMREQEKM 419
Score = 36.6 bits (83), Expect = 0.014
Identities = 36/172 (20%), Positives = 86/172 (50%), Gaps = 19/172 (11%)
Query: 14 RKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVIT--KT 71
+ W+++E K+ E++ E+++K + + ++E ++ ++ K+ + K+ K KT
Sbjct: 646 KMWEQEE--KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 72 TPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKK 131
Q +M ++S+ + KK + M E +Q +K E ++
Sbjct: 704 WDQEKMRE----------EESMRERE----KKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 132 KMEEKQKDYDFEERM-KELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
E+++K ++ EE+M ++ R E+K K ++ EK +E+++ E++ + +E
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Score = 36.6 bits (83), Expect = 0.014
Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 6/66 (9%)
Query: 124 KRFEVNKKKMEEKQKDYDFEERMKELREEE------EKAKAYKKEKQKEKKRRAEEDLTF 177
++ + +K E+++K ++ E+ K+ +E+E EK + + +++EKK R EE++
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 178 EEDDEM 183
E++++M
Sbjct: 731 EQEEKM 736
Score = 36.2 bits (82), Expect = 0.019
Identities = 20/72 (27%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
MR E ++ KK E + E+++K + EE+M+E +EE+ + +K +++E+K
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE--QEEKMWEQEEKMQEQEEKMWE 642
Query: 172 EEDLTFEEDDEM 183
+E+ +E++++M
Sbjct: 643 QEEKMWEQEEKM 654
Score = 35.8 bits (81), Expect = 0.025
Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E+ T DQ K R E + ++ E+K ++ EE M +EE+ + + K ++Q+E+ EE
Sbjct: 700 EKKTWDQEKMREEESMREREKKMRE---EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 175 LTFEEDDEM 183
+ +E++++M
Sbjct: 757 M-WEQEEKM 764
Score = 34.7 bits (78), Expect = 0.055
Identities = 22/86 (25%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKM-EEKQKDYDFEERMKELRE---EEEKAK 157
++ R MR E + + +++ + ++KM E+++K ++ EE+M+E E E+E+
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 158 AYKKEKQKEKKRRAEEDLTFEEDDEM 183
++EK E++R E+ E ++M
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKM 673
Score = 34.7 bits (78), Expect = 0.055
Identities = 20/61 (32%), Positives = 40/61 (65%), Gaps = 3/61 (4%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEE 179
+Q +K +E +KM+E++K ++ EE+M++ +EE+ + + K Q+EK R EE + +E
Sbjct: 772 EQKEKLWE--HEKMQEQEKIWEQEEKMRD-QEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 180 D 180
+
Sbjct: 829 E 829
Score = 34.3 bits (77), Expect = 0.072
Identities = 16/72 (22%), Positives = 45/72 (62%), Gaps = 2/72 (2%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
+R + + + +++ +K++ E++K+ E+ KELRE++E + ++ +++E+K
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKE--LREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 172 EEDLTFEEDDEM 183
+E+ E++++M
Sbjct: 360 QEEKMREQEEKM 371
Score = 33.1 bits (74), Expect = 0.16
Identities = 33/172 (19%), Positives = 81/172 (47%), Gaps = 17/172 (9%)
Query: 14 RKWDKDEYEKLAEKRLTEEREK-KDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTT 72
+ W ++E EK++ E+ +K +D + + E LR ++ ++ + K+ + + K
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQV--EKMR 427
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKK 132
+ +M D K + ++ R MR E T+ + +++ + ++
Sbjct: 428 EEKKMQEQEKKTRDQEEK--------MQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 133 MEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA-EEDLTFEEDDEM 183
M E++ E+ ++ R E+K K +++EK +E++ + E++ + +EM
Sbjct: 480 MWEQE-----EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526
Score = 31.6 bits (70), Expect = 0.47
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 43/174 (24%)
Query: 13 RRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKV-DLESKLGKTIVITKT 71
++ WD++E K+ E+ EREKK + + E++R ++ K+ + E K+ + K
Sbjct: 576 KKTWDQEE--KMREEERMREREKKMRE-----EEEMMREQEEKMQEQEEKMQEQE--EKM 626
Query: 72 TPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKK 131
Q E K Q E +Q +K +E ++
Sbjct: 627 WEQEE--------------------------KMQEQEEKMWEQEEKMWEQEEKMWE-QQR 659
Query: 132 KMEEKQKDYDFE--ERMKELREEEEKA----KAYKKEKQKEKKRRAEEDLTFEE 179
E+K+K ++ E + ++++E+EEK K KK +++EKK +E + EE
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Score = 31.2 bits (69), Expect = 0.61
Identities = 19/69 (27%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK---QKEKKRRA 171
E Q +K + +K +++K + EE+M+E + +E+ ++EK Q+EK R
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQ 880
Query: 172 EEDLTFEED 180
EE + +E+
Sbjct: 881 EEKMRGQEE 889
Score = 30.8 bits (68), Expect = 0.79
Identities = 19/73 (26%), Positives = 44/73 (60%), Gaps = 9/73 (12%)
Query: 115 ERSTLDQVKKRFEVNKKKM-------EEKQKDYDFEERMKELREEEEKAKAYKKEKQKEK 167
E +Q +K +E ++KM E+K+K ++ E+ ++ + +E++ K +++EK EK
Sbjct: 637 EEKMWEQEEKMWE-QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM-EK 694
Query: 168 KRRAEEDLTFEED 180
K + +E T++++
Sbjct: 695 KTQEQEKKTWDQE 707
Score = 30.8 bits (68), Expect = 0.79
Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 3/46 (6%)
Query: 130 KKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDL 175
++KMEEK + EE+M+E +EE+ + + K +Q+EK R EE +
Sbjct: 849 EEKMEEKMQGQ--EEKMRE-QEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 30.4 bits (67), Expect = 1.0
Identities = 21/85 (24%), Positives = 46/85 (54%), Gaps = 6/85 (7%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERM----KELREEEEKAK 157
+K +R + +V+ +TL + R E ++ E+K + EE+M + LRE+E K +
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMWRQEERLREQEGKMR 310
Query: 158 AYKKEKQKEKKRRAEEDLTFEEDDE 182
+++ +++KR E++ E ++
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEK 335
Score = 30.0 bits (66), Expect = 1.4
Identities = 19/83 (22%), Positives = 45/83 (54%), Gaps = 10/83 (12%)
Query: 111 SMRVERSTLDQVKKRFEVNKKKMEEKQKD--------YDFEERMKELREE--EEKAKAYK 160
SMR + + ++ ++KM+E+++ ++ EE+M E E+ E++ +
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 161 KEKQKEKKRRAEEDLTFEEDDEM 183
KEK E ++ E++ +E++++M
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKM 796
Score = 28.9 bits (63), Expect = 3.0
Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQK--EKKRRAE 172
E Q +K + +K +++K + EE+M E+ E+ ++EK + E+K R +
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Query: 173 EDLTFEEDDEM 183
E+ E++++M
Sbjct: 874 EEKMREQEEKM 884
Score = 27.7 bits (60), Expect = 6.7
Identities = 16/65 (24%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMK---ELREEEEKAKAYKKEKQKEKKRRAEEDLTF 177
++K++ E K + + Q + EE + ELRE+E+K + +++ ++++R E++
Sbjct: 250 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 309
Query: 178 EEDDE 182
E +E
Sbjct: 310 REQEE 314
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 2e-05
Identities = 25/73 (34%), Positives = 47/73 (64%), Gaps = 5/73 (6%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAY-KKEKQKEKKRR 170
MR E+ T +Q KK ++ +K EE++ ER K++REEEE + +K +++E+K R
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEER----MREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 171 AEEDLTFEEDDEM 183
+E+ +E++++M
Sbjct: 592 EQEEKMWEQEEKM 604
Score = 44.3 bits (103), Expect = 7e-05
Identities = 40/187 (21%), Positives = 89/187 (47%), Gaps = 18/187 (9%)
Query: 13 RRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRE-LLRHRDYKVDLESKLGKTIVITKT 71
++ W ++E K+ E++ T+E+EKK + ++ E +R R+ K+ E ++ +
Sbjct: 527 KKMWQQEE--KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 72 TPQSEMGGYYCNVCDCVVK----------DSINFLDHINGKKHQRNLGMSMRVERSTLDQ 121
+ +M + + K + K Q M E +Q
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 122 VKKRFEVNKKKMEEKQKDYDFEERMK----ELREEEEKAKAYK-KEKQKEKKRRAEEDLT 176
+K +E +K E+++K + EE+M+ ++RE+EEK + + K +++E+K R +E+
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Query: 177 FEEDDEM 183
+ ++++M
Sbjct: 705 WGQEEKM 711
Score = 41.6 bits (96), Expect = 4e-04
Identities = 23/87 (26%), Positives = 49/87 (56%), Gaps = 5/87 (5%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE-----LREEEEKA 156
+K R +R + L + KK E ++ E+++K ++ EE+M+E R+EE
Sbjct: 282 EKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 341
Query: 157 KAYKKEKQKEKKRRAEEDLTFEEDDEM 183
+ K+ +++E+K R +E+ +E+D+ +
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERL 368
Score = 41.6 bits (96), Expect = 4e-04
Identities = 20/72 (27%), Positives = 45/72 (62%), Gaps = 4/72 (5%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
+R + + + KK ++ +K EEK+ +E+ K+ ++EEK + ++ +++EKK R
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKT----QEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 172 EEDLTFEEDDEM 183
EE++ E++++M
Sbjct: 572 EEEMMREQEEKM 583
Score = 40.8 bits (94), Expect = 8e-04
Identities = 23/86 (26%), Positives = 50/86 (58%), Gaps = 5/86 (5%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE---LREEEEKAKA 158
+K R MR + + + +R +++M E++K ++ EE+M+E +RE E+K +
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 159 YKK--EKQKEKKRRAEEDLTFEEDDE 182
++ +Q+EK ++ EE++ +E+ E
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKE 429
Score = 40.8 bits (94), Expect = 8e-04
Identities = 21/72 (29%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE---LREEEEKAKAYKKEKQKEKKRRA 171
E+ +Q +K + ++ E+ ++ + EERM+E + E+EEK + ++ +++EKK R
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 172 EEDLTFEEDDEM 183
EE+ E++++M
Sbjct: 404 EEETMREQEEKM 415
Score = 40.8 bits (94), Expect = 8e-04
Identities = 26/74 (35%), Positives = 46/74 (62%), Gaps = 10/74 (13%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKE----LREEEEKAKAYKK-----EKQKEKKRR 170
+Q + +E +K +++QK +D EERM E LRE+EE+ + KK EK +E+K+
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 171 AE-EDLTFEEDDEM 183
E E T++++++M
Sbjct: 543 QEQEKKTWDQEEKM 556
Score = 40.0 bits (92), Expect = 0.001
Identities = 37/167 (22%), Positives = 76/167 (45%), Gaps = 19/167 (11%)
Query: 17 DKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSE 76
+++E + E+ + E+ EK+ + P ++E L ++ + E K+ + K Q E
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE--EKIRDQEE 467
Query: 77 MGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEK 136
M G + +K + E DQ +K ++ ++ E+
Sbjct: 468 MWGQEKKMW--------------RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513
Query: 137 QKDYDFEERMKELR---EEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
++ + EERM+E + ++EEK + KK +++EKK +E+ EE+
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Score = 39.3 bits (90), Expect = 0.002
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 4/69 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
ER + K R + K + +EK+ E+ KELRE+E++ + KK +++E++ + +E+
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKR----LREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 175 LTFEEDDEM 183
+E++++M
Sbjct: 318 KMWEQEEKM 326
Score = 34.3 bits (77), Expect = 0.072
Identities = 23/91 (25%), Positives = 49/91 (53%), Gaps = 9/91 (9%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEK-----QKDYDFEERMKE----LREE 152
+K +R + +V+ +TL + R E ++ E+K +K + EER++E +RE+
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 153 EEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
EEK + +K ++++K E++ E ++
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKL 305
Score = 33.9 bits (76), Expect = 0.094
Identities = 15/72 (20%), Positives = 45/72 (62%), Gaps = 2/72 (2%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
+R + + + +++ +K++ E++K+ E+ KELRE+++ + ++ +++E+K
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKE--LREQEKELREQKKLREQEEQMQEQEEKMWE 321
Query: 172 EEDLTFEEDDEM 183
+E+ E++++M
Sbjct: 322 QEEKMREQEEKM 333
Score = 32.3 bits (72), Expect = 0.27
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 33/180 (18%)
Query: 14 RKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTP 73
R W++DE + E+R+ E+ EK + + + E +R R+ K+ E + T
Sbjct: 360 RMWEQDERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEE---------TMR 409
Query: 74 QSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKM 133
+ E + + K N + + Q+ L ++ L + +K E +K
Sbjct: 410 EQE---------EKMQKQEENMWEQEEKEWQQQRLPE----QKEKLWEQEKMQEQEEKIW 456
Query: 134 EEKQKDYDFEE---------RMKELREEEEKA-KAYKKEKQKEKKRRAEEDLTFEEDDEM 183
E+++K D EE R +++RE+E++ + +K + +E+K +E+ +E+D+ +
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
Score = 30.8 bits (68), Expect = 0.79
Identities = 17/77 (22%), Positives = 44/77 (57%), Gaps = 5/77 (6%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEE-KQKDYDFEERM----KELREEEEKAKAYKKEKQKE 166
+R + + + +++ ++KM E ++K + EER+ K++RE+E+K + ++ ++
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 167 KKRRAEEDLTFEEDDEM 183
+R E++ E ++M
Sbjct: 365 DERLREKEERMREQEKM 381
Score = 30.0 bits (66), Expect = 1.4
Identities = 17/71 (23%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK--QKEKKR 169
MR + + + +++ + ++KM E+++ +E +++RE+EEK + +++ Q+EK
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQGQE--EKMREQEEKMRGQEEKMWGQEEKMW 712
Query: 170 RAEEDLTFEED 180
EE + +E+
Sbjct: 713 GQEEKMWGQEE 723
Score = 28.1 bits (61), Expect = 5.1
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERM---KELREEEEKAKAYKKEKQKEKKRRA 171
E +Q +K +K +++K + EE+M +E+RE+EE+ + +KEK +E+
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD-QKEKMQERLPEH 745
Query: 172 EE 173
EE
Sbjct: 746 EE 747
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 45.8 bits (107), Expect = 2e-05
Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 10/171 (5%)
Query: 14 RKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTP 73
R+ K + EK ++L E+ E + GK Q ++E R K + E+ K V T P
Sbjct: 238 RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQR----KFEEETVKSKVTVDTGVIP 293
Query: 74 QSE------MGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFE 127
SE N D KD K+ ++ G S ++ + + K E
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE 353
Query: 128 VNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFE 178
+++ E+++ E ++ R+EEE+ + K+E++K+K++ +E L E
Sbjct: 354 EEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Score = 33.1 bits (74), Expect = 0.16
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 91 DSINFLDHINGKKHQRNLGMSMRVERSTLD-----QVKKRFEVNKKKMEEKQKDYDFEE- 144
+S FL G+K + +E D ++K + +K E ++K D E+
Sbjct: 189 ESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKA 248
Query: 145 RMKELREEEEKAKAYK-KEKQKEKKRRAEED 174
++++L+E+EE K + KQKE +R+ EE+
Sbjct: 249 KLRKLKEKEELETGKKDQSKQKESQRKFEEE 279
Score = 32.3 bits (72), Expect = 0.27
Identities = 18/60 (30%), Positives = 30/60 (50%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E D+ ++ E NK +E K+ + EE +E E+EE + ++E + E EED
Sbjct: 507 EAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
Score = 31.6 bits (70), Expect = 0.47
Identities = 13/35 (37%), Positives = 25/35 (71%)
Query: 130 KKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQ 164
KKK E+K++D+D ++ +KEL E +A+ K +++
Sbjct: 43 KKKKEKKKQDFDEDDILKELEELSLEAQGIKADRE 77
Score = 29.3 bits (64), Expect = 2.3
Identities = 16/64 (25%), Positives = 34/64 (53%)
Query: 110 MSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKR 169
M+ E ++ K EV + EE++++ + EE + EEEE+ ++ E +E ++
Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEK 568
Query: 170 RAEE 173
++E
Sbjct: 569 VSDE 572
Score = 28.5 bits (62), Expect = 3.9
Identities = 17/67 (25%), Positives = 35/67 (52%)
Query: 131 KKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVMGFS 190
+K+E + + +E +E EEEE+ + ++ +++E++ E +E+DE + S
Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575
Query: 191 GFGSTKK 197
G KK
Sbjct: 576 GKTLDKK 582
Score = 28.5 bits (62), Expect = 3.9
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 128 VNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMA--- 184
++KK +E D +++ +EE +AY K K++ +KRR E + A
Sbjct: 579 LDKKPSKEMSSDSEYDSDDDRTKEE----RAYDKAKRRIEKRRLEHSKNVNTEKLRAPII 634
Query: 185 AVMGFSGFGSTK 196
V+G G TK
Sbjct: 635 CVLGHVDTGKTK 646
Score = 28.1 bits (61), Expect = 5.1
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 6/61 (9%)
Query: 130 KKKMEEKQKD-YDFEERMKELR-----EEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
K K E+ KD D + E+ +E+E K+ K+K+++KK+ +ED +E +E+
Sbjct: 6 KNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEEL 65
Query: 184 A 184
+
Sbjct: 66 S 66
Score = 27.3 bits (59), Expect = 8.8
Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 11/73 (15%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKEL--------REEEEKAKAYK---KEKQKEKKR 169
+VK+ E +++ EE+++D + EE +E EE+EK K K K+ +
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Query: 170 RAEEDLTFEEDDE 182
D ++ DD+
Sbjct: 586 EMSSDSEYDSDDD 598
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 45.8 bits (107), Expect = 2e-05
Identities = 44/183 (24%), Positives = 75/183 (40%), Gaps = 21/183 (11%)
Query: 13 RRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTT 72
R + + D E E+R E EK+D + ++ +++DY VD E + K +
Sbjct: 83 RMEMELDYAEDATERRRVLEVEKEDTEELRQ------KYKDY-VDKEKAIAKAL------ 129
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKK 132
+ +YC +CD + F +HIN H + +R V R ++KK
Sbjct: 130 -EDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKK 188
Query: 133 MEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVMGFSGF 192
E+ + R+ EL E+ ++A+ K D EDD+ + SG
Sbjct: 189 QEKALR------RLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATN-SGT 241
Query: 193 GST 195
G+T
Sbjct: 242 GAT 244
Score = 32.3 bits (72), Expect = 0.27
Identities = 20/60 (33%), Positives = 28/60 (46%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
ERS K+ + +KK + K+K E E EK+K KK K+K+ K A D
Sbjct: 667 ERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPAD 726
Score = 28.5 bits (62), Expect = 3.9
Identities = 15/55 (27%), Positives = 30/55 (54%)
Query: 116 RSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRR 170
RS + ++ + ++ K ++K K +R + EE+ +KA EK K++K+R
Sbjct: 660 RSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKR 714
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 45.4 bits (106), Expect = 3e-05
Identities = 29/96 (30%), Positives = 57/96 (59%), Gaps = 12/96 (12%)
Query: 82 CNVCDC--VVKDSINFLD-HINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQK 138
C VC +V D+ + +D H+ GK+H M ++T++++K++ +K+ EE +
Sbjct: 192 CEVCGAFLIVGDAQSRVDDHLMGKQH-----MGYAKIKATVEELKEKL---RKRTEEPDR 243
Query: 139 DYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
D ++ +E REE EK + ++E+++ K+RR EE+
Sbjct: 244 DERLKKEKQE-REEREKEREREREERERKRRREEEE 278
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 45.4 bits (106), Expect = 3e-05
Identities = 29/96 (30%), Positives = 57/96 (59%), Gaps = 12/96 (12%)
Query: 82 CNVCDC--VVKDSINFLD-HINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQK 138
C VC +V D+ + +D H+ GK+H M ++T++++K++ +K+ EE +
Sbjct: 192 CEVCGAFLIVGDAQSRVDDHLMGKQH-----MGYAKIKATVEELKEKL---RKRTEEPDR 243
Query: 139 DYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
D ++ +E REE EK + ++E+++ K+RR EE+
Sbjct: 244 DERLKKEKQE-REEREKEREREREERERKRRREEEE 278
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/197 (22%), Positives = 91/197 (46%), Gaps = 18/197 (9%)
Query: 17 DKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVI----TKTT 72
+K + + E ++ +E+ KKD +P + VK + R + + +++S+ G+ + T+ T
Sbjct: 190 EKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGF-TEVKSQNGEFMTHKLKHTENT 248
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST---------LDQVK 123
G + + + + + +R S E+ L+++K
Sbjct: 249 FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 308
Query: 124 KRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED--- 180
K+ E +K +EE+++ EE ++LREEEEK + K+E ++ + AE+ ED
Sbjct: 309 KKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAEKRQKMPEDGLS 367
Query: 181 DEMAAVMGFSGFGSTKK 197
D+ F+ GS+ K
Sbjct: 368 DDKKPFKCFTPKGSSLK 384
Score = 35.0 bits (79), Expect = 0.042
Identities = 35/186 (18%), Positives = 75/186 (40%), Gaps = 12/186 (6%)
Query: 23 KLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGGYYC 82
++A +R ++ E+ + + ++E LR + + L + V + + E
Sbjct: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
Query: 83 NVCDCVVKDSINFLDHINGKKHQRNLGMSMRVER----------STLDQVKKRFEVNKKK 132
D FL+ + ++ +R + +ER ++L +R + + +
Sbjct: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
Query: 133 MEEKQKDYDFEERMK--ELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVMGFS 190
E +K+ E R + E+ E E K+Y+K ++ + +ED EE++E G
Sbjct: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
Query: 191 GFGSTK 196
G K
Sbjct: 198 GENQIK 203
Score = 30.0 bits (66), Expect = 1.4
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVN------KKKMEEKQKDYDFEERMKELREEEEK 155
+K +++ R E + V K ++ N + K E+K+K+ + EE+ K E +
Sbjct: 142 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 201
Query: 156 AKAYKKEKQKEKKRRAE 172
K K +K KE K +
Sbjct: 202 IKDEKIKKDKEPKEEVK 218
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/197 (22%), Positives = 91/197 (46%), Gaps = 18/197 (9%)
Query: 17 DKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVI----TKTT 72
+K + + E ++ +E+ KKD +P + VK + R + + +++S+ G+ + T+ T
Sbjct: 196 EKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGF-TEVKSQNGEFMTHKLKHTENT 254
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST---------LDQVK 123
G + + + + + +R S E+ L+++K
Sbjct: 255 FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 314
Query: 124 KRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED--- 180
K+ E +K +EE+++ EE ++LREEEEK + K+E ++ + AE+ ED
Sbjct: 315 KKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAEKRQKMPEDGLS 373
Query: 181 DEMAAVMGFSGFGSTKK 197
D+ F+ GS+ K
Sbjct: 374 DDKKPFKCFTPKGSSLK 390
Score = 38.5 bits (88), Expect = 0.004
Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 12/189 (6%)
Query: 20 EYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGG 79
E E++A +R ++ E+ + + ++E LR + + L + V + + E
Sbjct: 21 EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAK 80
Query: 80 YYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVER----------STLDQVKKRFEVN 129
D FL+ + ++ +R + +ER ++L +R + +
Sbjct: 81 TTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQND 140
Query: 130 KKKMEEKQKDYDFEERMK--ELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVM 187
+ E +K+ E R + E+ E E K+Y+K ++ + +ED EE++E
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 188 GFSGFGSTK 196
G G K
Sbjct: 201 GSIGENQIK 209
Score = 30.0 bits (66), Expect = 1.4
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 6/77 (7%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVN------KKKMEEKQKDYDFEERMKELREEEEK 155
+K +++ R E + V K ++ N + K E+K+K+ + EE+ K E +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 207
Query: 156 AKAYKKEKQKEKKRRAE 172
K K +K KE K +
Sbjct: 208 IKDEKIKKDKEPKEEVK 224
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 43.1 bits (100), Expect = 2e-04
Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 8/76 (10%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE---LREEEEKAKAYKKEKQK---E 166
RVE+ D++++ E K+K EE++ + E R +E R+EEEK K +EK+K E
Sbjct: 422 RVEKEEQDRLER--EELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEE 479
Query: 167 KKRRAEEDLTFEEDDE 182
KR+AEE+L +E E
Sbjct: 480 AKRKAEEELLLKEKQE 495
Score = 35.8 bits (81), Expect = 0.025
Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
ER L++ ++ E +K+ EE++K + EE+ K EE K KA ++ KEK+ + +++
Sbjct: 443 ERLRLEEEARKQEEERKRQEEEKKKQEGEEKRK--AGEEAKRKAEEELLLKEKQEQEKQE 500
Query: 175 LTFEEDDEMAA 185
E + AA
Sbjct: 501 KAMIEKQKEAA 511
Score = 35.4 bits (80), Expect = 0.032
Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 105 QRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKEL---REEEEKAKAYKK 161
++ L R ER +++ + K+K Q + EER ++L R+ E++ +A +
Sbjct: 54 RQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVE 113
Query: 162 EKQKEKKRRAEEDL 175
EK+K+K R EE L
Sbjct: 114 EKRKQKLREEEERL 127
Score = 33.9 bits (76), Expect = 0.094
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 88 VVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMK 147
V K+ + L+ K+ + + E ++ +KR E KKK E ++K EE +
Sbjct: 423 VEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKR 482
Query: 148 ELREE---EEKAKAYKKEKQK-EKKRRAEEDLTFEEDDEM 183
+ EE +EK + K+EK EK++ A E E ++M
Sbjct: 483 KAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQM 522
Score = 32.3 bits (72), Expect = 0.27
Identities = 15/53 (28%), Positives = 32/53 (60%)
Query: 130 KKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
++++E++++D E +K EEE + KQ+E+++R EE+ +E +E
Sbjct: 420 QERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEE 472
Score = 30.0 bits (66), Expect = 1.4
Identities = 16/71 (22%), Positives = 39/71 (54%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E+ +++K E ++ +E+Q + EE ++ EE + + +++++E+KR+ EE
Sbjct: 406 EKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEK 465
Query: 175 LTFEEDDEMAA 185
E +++ A
Sbjct: 466 KKQEGEEKRKA 476
Score = 28.9 bits (63), Expect = 3.0
Identities = 19/63 (30%), Positives = 38/63 (60%), Gaps = 3/63 (4%)
Query: 124 KRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
+R + K++ EE++K R +++ E++++A+ + EKQ E++ R E+ ED +
Sbjct: 53 ERQRLAKERREEREKC--LAAREQQILEKQKRARL-QYEKQMEERWRKLEEQRQREDQKR 109
Query: 184 AAV 186
AAV
Sbjct: 110 AAV 112
Score = 28.9 bits (63), Expect = 3.0
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 11/61 (18%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDF------EERMKELREEEEKAKA-----YKKEKQKEKKR 169
Q +K+ E +K+EE+++ D E+R ++LREEEE+ +A ++ +Q E K+
Sbjct: 86 QYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKK 145
Query: 170 R 170
+
Sbjct: 146 K 146
Score = 27.7 bits (60), Expect = 6.7
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
Query: 133 MEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
ME K + + KE REE EK A ++++ EK++RA L +E+ E
Sbjct: 45 MEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAR--LQYEKQME 92
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 42.7 bits (99), Expect = 2e-04
Identities = 45/185 (24%), Positives = 89/185 (48%), Gaps = 22/185 (11%)
Query: 13 RRKWD-----KDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIV 67
R++W+ KDE ++ E+ L EEREK + +Q +R+ + + + E LG+
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREK---RRLQERERQYREEEELQQEEEQLLGEE-- 1067
Query: 68 ITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKK--R 125
+T + E+ Y + + ++ L K+ ++ R E + ++ R
Sbjct: 1068 -RETRRRQELERQYRKE-EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 126 FEVNKKKMEEKQKDYDFEERMKE-----LREEEEKAKAYKKEKQ---KEKKRRAEEDLTF 177
E K++ +E ++ Y EE +++ LREE EK + + E+Q +E+ ++ EE L
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 178 EEDDE 182
EE ++
Sbjct: 1186 EEQEK 1190
Score = 42.4 bits (98), Expect = 3e-04
Identities = 42/173 (24%), Positives = 83/173 (47%), Gaps = 20/173 (11%)
Query: 18 KDEYEKLAEKRLTEEREKKDGKPVQPVKR-ELLRHRDYKVDL----ESKLGKTIVITKTT 72
++E EK ++R ER+ ++ + +Q KR + R D + DL E + + K
Sbjct: 1185 REEQEKRRQER---ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY 1241
Query: 73 PQSEMGGYYCNVCDCVVKD--SINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNK 130
+ + + D ++D S L H+ G++ +R+ ER Q + F +
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD----REQERRRWQQRDRHFPEEE 1297
Query: 131 KKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
+ E+QK E + ++ + +EEK +E+++EK+RR E D F E++++
Sbjct: 1298 QLEREEQK----EAKRRDRKSQEEKQLL--REEREEKRRRQETDRKFREEEQL 1344
Score = 41.2 bits (95), Expect = 6e-04
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
Query: 97 DHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQ-----KDYDFEERMKELRE 151
D + ++ +R R + L+Q KR EV + + EE++ ++ EER ++L +
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 152 EEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
EE+ + +++ ++E++ R E+ L EE++E
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEE 666
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/81 (29%), Positives = 48/81 (59%), Gaps = 10/81 (12%)
Query: 112 MRVERSTLDQVKK---RFEVNKKKMEEKQKDYDFEERMKE-----LREEEEKAKAYKKEK 163
+R E+ L + ++ R E K++ +E+++ Y EE++++ LREE EK + ++E+
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
Query: 164 Q--KEKKRRAEEDLTFEEDDE 182
Q K+KK + +E+ E+ E
Sbjct: 959 QYRKDKKLQQKEEQLLGEEPE 979
Score = 36.6 bits (83), Expect = 0.014
Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 10/82 (12%)
Query: 111 SMRVERSTLDQVKKRFEVNKKKMEEKQKD--YDFEERMKELREEE-----EKAKAYKKEK 163
S +R ++ + R E ++++ +Q+D Y +EE +L E+E E+ + Y+ E+
Sbjct: 1790 SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEE 1849
Query: 164 Q---KEKKRRAEEDLTFEEDDE 182
Q +EK RR E++L EE+ +
Sbjct: 1850 QFATQEKSRREEQELWQEEEQK 1871
Score = 35.8 bits (81), Expect = 0.025
Identities = 16/81 (19%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
K ++ L + E ++++ ++ +K+ EE+++ + +E RE++E+ + ++
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR--EQ 337
Query: 162 EKQKEKKRRAEEDLTFEEDDE 182
+ ++E++ R E+ L E+++E
Sbjct: 338 QLRREQEERREQQLRREQEEE 358
Score = 35.8 bits (81), Expect = 0.025
Identities = 17/81 (20%), Positives = 50/81 (61%), Gaps = 3/81 (3%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
++ Q+ L ++ R + ++R + +++ ++++++ E R ++LR E+E+ + +
Sbjct: 294 EQQQQRLRREQQLRRK--QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 162 EKQKEKKRRAEEDLTFEEDDE 182
+++E++RR E+ L E+++E
Sbjct: 352 RREQEEERR-EQQLRREQEEE 371
Score = 35.8 bits (81), Expect = 0.025
Identities = 20/76 (26%), Positives = 42/76 (55%), Gaps = 15/76 (19%)
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREE---EEKAKAYKKEK------------QKEK 167
++R E ++ EE+Q + E+ ++E RE+ +E+ + Y+K+K + EK
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 168 KRRAEEDLTFEEDDEM 183
+RR E + + E++E+
Sbjct: 981 RRRQEREKKYREEEEL 996
Score = 35.8 bits (81), Expect = 0.025
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 8/64 (12%)
Query: 127 EVNKKKMEEKQKDYDFEERMKE-----LREEEEKAKAYKKEKQKEKK---RRAEEDLTFE 178
E K++ +E++K Y EE +++ LREE EK + + E+Q KK ++ EE L E
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 179 EDDE 182
E ++
Sbjct: 1037 EREK 1040
Score = 35.4 bits (80), Expect = 0.032
Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 5/84 (5%)
Query: 103 KHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKE 162
K ++ L R ++ D+ +K F ++++ +++D F E +++R +E + K ++E
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRK-FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 163 KQ----KEKKRRAEEDLTFEEDDE 182
+Q + +K R EE L E +++
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQ 1476
Score = 35.0 bits (79), Expect = 0.042
Identities = 19/78 (24%), Positives = 47/78 (60%), Gaps = 3/78 (3%)
Query: 99 INGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEE---KQKDYDFEERMKELREEEEK 155
++ +K R G ++ ++ ++RFE +++EE +++ +E+ +EL E EE+
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 156 AKAYKKEKQKEKKRRAEE 173
++ ++ +Q++++RR EE
Sbjct: 155 SEKQERLEQRDRQRRDEE 172
Score = 35.0 bits (79), Expect = 0.042
Identities = 35/178 (19%), Positives = 82/178 (46%), Gaps = 11/178 (6%)
Query: 13 RRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTT 72
RR+ +++ E+ + EER ++ + Q ++RE R+ ++ E +L + + +
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR-- 409
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKK 132
+ ++ + ++ H + +R R + D +K+ E + +
Sbjct: 410 -EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 133 MEEKQKDY--DFEERMKE----LREEEEKAKAYKKEKQ--KEKKRRAEEDLTFEEDDE 182
E +++ D EE +E L EEE + + ++E+Q +E++ R E+ L +E++E
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 34.7 bits (78), Expect = 0.055
Identities = 21/74 (28%), Positives = 45/74 (60%), Gaps = 6/74 (8%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKR--- 169
R ++ DQ ++R E K+EE+++ E R ++LR E+E+ + + ++Q+E++R
Sbjct: 472 RKQQLKRDQEEERRE-RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 170 --RAEEDLTFEEDD 181
R+E+ L E+++
Sbjct: 531 RLRSEQQLRREQEE 544
Score = 34.7 bits (78), Expect = 0.055
Identities = 34/175 (19%), Positives = 80/175 (45%), Gaps = 23/175 (13%)
Query: 13 RRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTT 72
R +W K E E+ E++ E RE++ + + + + L+ ++ + L+ +L + +
Sbjct: 485 RERWLKLEEEERREQQ--ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKK 132
+ ++ + + + +R R + DQ+ KR E +++
Sbjct: 543 EER--------------REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
Query: 133 MEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED-----LTFEEDDE 182
+++++ E+R+K REE E+ + ++ +Q+ K+ EE+ L EE +E
Sbjct: 589 RLKREQEERLEQRLK--REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Score = 34.3 bits (77), Expect = 0.072
Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 7/60 (11%)
Query: 125 RFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK----QKEKKRRAEEDLTFEED 180
R E K++ +E+++ Y + K+L+++EE+ + EK ++EKK R EE+L EE+
Sbjct: 945 REEREKRRRQERERQY---RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Score = 33.5 bits (75), Expect = 0.12
Identities = 22/73 (30%), Positives = 43/73 (58%), Gaps = 3/73 (4%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+K Q+ RV + ++ ++ E +K EEK ++ + +R +EL+EEEE+ + K
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE-PQRQRELQEEEEQLR--KL 281
Query: 162 EKQKEKKRRAEED 174
E+Q+ ++ R EE+
Sbjct: 282 ERQELRRERQEEE 294
Score = 33.1 bits (74), Expect = 0.16
Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 5/61 (8%)
Query: 127 EVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQ-----KEKKRRAEEDLTFEEDD 181
E ++++ +++D F E ++LR +E + K ++E+Q E+K R EE L E +
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Query: 182 E 182
E
Sbjct: 1738 E 1738
Score = 32.7 bits (73), Expect = 0.21
Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 14/74 (18%)
Query: 122 VKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQ------------KEKKR 169
++++ ++ ++E++++ EER K R+E+E + Y++E+Q +EK+R
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQE--RQYREEEQLQQEEEQLLREEREKRR 952
Query: 170 RAEEDLTFEEDDEM 183
R E + + +D ++
Sbjct: 953 RQERERQYRKDKKL 966
Score = 32.7 bits (73), Expect = 0.21
Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 11/83 (13%)
Query: 112 MRVERSTLDQVKKRFEVNK-KKMEEKQKDYDFEERMKELREEEEKAKAYKKE-------- 162
+R ER + ++ + K KK+++K++ EE K R+E EK ++E
Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Query: 163 --KQKEKKRRAEEDLTFEEDDEM 183
+++EK+RR E + + + DE+
Sbjct: 1004 LREEREKRRRQEWERQYRKKDEL 1026
Score = 32.3 bits (72), Expect = 0.27
Identities = 19/93 (20%), Positives = 46/93 (49%), Gaps = 12/93 (12%)
Query: 103 KHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKE 162
+ ++ L R ++ D+ +K E + + E +++ +ER ++ R EE+K + ++E
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 163 K------------QKEKKRRAEEDLTFEEDDEM 183
+ + +++ R E D F ED+++
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Score = 32.0 bits (71), Expect = 0.36
Identities = 19/81 (23%), Positives = 41/81 (50%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+K R +R E L + + + + ++ EE+ + + +E +E +EEE++ + ++
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 162 EKQKEKKRRAEEDLTFEEDDE 182
E+Q +K+ E EE E
Sbjct: 303 EQQLRRKQEEERREQQEERRE 323
Score = 32.0 bits (71), Expect = 0.36
Identities = 19/60 (31%), Positives = 36/60 (60%), Gaps = 7/60 (11%)
Query: 125 RFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK----QKEKKRRAEEDLTFEED 180
R E K++ +E ++ Y + EL++EEE+ ++EK ++E++ R EE+L EE+
Sbjct: 1005 REEREKRRRQEWERQY---RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Score = 31.6 bits (70), Expect = 0.47
Identities = 17/71 (23%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEE---KAKAYKKEKQKEKKRRA 171
+R +Q + E +K +EE+Q+ + + + K L+EE++ + + ++ + +++K R
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559
Query: 172 EEDLTFEEDDE 182
EE L E +++
Sbjct: 1560 EEQLRQEREEQ 1570
Score = 31.6 bits (70), Expect = 0.47
Identities = 18/82 (21%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 105 QRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEK---AKAYKK 161
+R ++ + T + +R E +K +EE+Q + EE+ +E + K + ++
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Query: 162 EKQKEKKRRAEEDLTFEEDDEM 183
E+++++ R E D F E++++
Sbjct: 1782 EREEQQLRSQESDRKFREEEQL 1803
Score = 31.2 bits (69), Expect = 0.61
Identities = 16/68 (23%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E Q+ K E +++ ++ +++ + REEEE+ + +++ E++RR E++
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR-EQE 684
Query: 175 LTFEEDDE 182
L EE ++
Sbjct: 685 LAEEEQEQ 692
Score = 31.2 bits (69), Expect = 0.61
Identities = 23/115 (20%), Positives = 52/115 (45%), Gaps = 35/115 (30%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEK------ 155
++ +R R ++ +Q KR E ++ + +++++ E R +EL EEE++
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697
Query: 156 -------------------AKAY----------KKEKQKEKKRRAEEDLTFEEDD 181
+K Y ++++Q+EK+RR E +L ++E++
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Score = 31.2 bits (69), Expect = 0.61
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 7/69 (10%)
Query: 116 RSTLDQVKKRFEVNKKKMEEKQKDYDF--EERMKELREEEEKAKAYKKEKQKEKKRRAEE 173
R L++ + R E ++++ +++D F EE++++ REE++ + ++ ++K R EE
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ-----LRSQESDRKFREEE 1801
Query: 174 DLTFEEDDE 182
L E +++
Sbjct: 1802 QLRQEREEQ 1810
Score = 30.8 bits (68), Expect = 0.79
Identities = 14/67 (20%), Positives = 40/67 (59%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
R ++ + ++R E +++ E++ + E R ++LR E+E+ + ++ ++++++ R E
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Query: 173 EDLTFEE 179
+ L E+
Sbjct: 375 QQLRREQ 381
Score = 30.8 bits (68), Expect = 0.79
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 7/71 (9%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQ--KEKKRRAE 172
E +Q ++R + +++ EE++ E+R+K EEE + + E+Q +E++ R E
Sbjct: 493 EEERREQQERREQQLRREQEERR-----EQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 173 EDLTFEEDDEM 183
+ L EE+ +
Sbjct: 548 QLLKREEEKRL 558
Score = 30.8 bits (68), Expect = 0.79
Identities = 14/69 (20%), Positives = 39/69 (56%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
++ Q+ L + ER +++ E +++++ ++++ E+R+K EEE + + +
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 162 EKQKEKKRR 170
E+Q++ + R
Sbjct: 688 EEQEQARER 696
Score = 30.8 bits (68), Expect = 0.79
Identities = 15/60 (25%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
++R E++++ EER + RE+ + +KE+++ ++R E++L F E++E
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQ--REQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Score = 30.8 bits (68), Expect = 0.79
Identities = 17/74 (22%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQK---EKKR 169
R + DQ K R+++ +++ + Y ++LR+E++ + ++E Q+ EK+R
Sbjct: 864 RSQEQRRDQ-KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 170 RAEEDLTFEEDDEM 183
R E++ + E++++
Sbjct: 923 RQEQERQYREEEQL 936
Score = 30.8 bits (68), Expect = 0.79
Identities = 16/68 (23%), Positives = 40/68 (58%), Gaps = 4/68 (5%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK----QKEKKRRAEEDL 175
D+ +K E + E +++ +ER ++ REEE++ + ++E+ ++++ RR E +
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 176 TFEEDDEM 183
F E++++
Sbjct: 1724 KFREEEQL 1731
Score = 30.8 bits (68), Expect = 0.79
Identities = 14/61 (22%), Positives = 33/61 (54%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
+R ER + +++F +K E+Q+ + EE+ + E + + + + +QKE++R
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896
Query: 172 E 172
+
Sbjct: 1897 Q 1897
Score = 30.4 bits (67), Expect = 1.0
Identities = 16/70 (22%), Positives = 42/70 (60%), Gaps = 7/70 (10%)
Query: 120 DQVKKRFEVNKKKMEEKQ---KDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA----E 172
+Q +++ +++ E++ ++ + E+R ++ RE E++ + ++E+Q +++ RA E
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 173 EDLTFEEDDE 182
E+ +ED E
Sbjct: 852 EEDGLQEDQE 861
Score = 30.4 bits (67), Expect = 1.0
Identities = 32/180 (17%), Positives = 80/180 (44%), Gaps = 16/180 (8%)
Query: 11 DFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITK 70
D + +W+ ++ + + ++ + ++ + + ++ LR R + DL+ LG+ +
Sbjct: 1222 DLKWQWEPEKENAVRDNKVY--CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ---QE 1276
Query: 71 TTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNK 130
+ E + ++ + + K+ R ++ R ++ ++R E ++
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 131 KKMEEKQKDYDFE-------ERMKELREEE----EKAKAYKKEKQKEKKRRAEEDLTFEE 179
K EE+Q + E ER ++ REEE E+ + + +E+Q+ +++ E EE
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Score = 30.0 bits (66), Expect = 1.4
Identities = 16/68 (23%), Positives = 42/68 (61%), Gaps = 5/68 (7%)
Query: 121 QVKKRFEVNKKK---MEEKQKDYDFEERMKELREEEEKAKAYKK--EKQKEKKRRAEEDL 175
Q +K+ E+ +++ + E+++ +ER ++ REEEE + ++ +++E +RR E +
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 176 TFEEDDEM 183
+ +++E+
Sbjct: 1079 QYRKEEEL 1086
Score = 30.0 bits (66), Expect = 1.4
Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 4/64 (6%)
Query: 120 DQVKKRFEVNKKKMEEKQK----DYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDL 175
+Q R E ++K +EE+Q+ + D + R +ELR +E + K ++E+Q +++R + L
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Query: 176 TFEE 179
E+
Sbjct: 1535 QEEQ 1538
Score = 29.6 bits (65), Expect = 1.8
Identities = 15/78 (19%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
++ +R R ++ + + R E +++ ++ +++ + E R ++LR E+E+ + ++
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR-EQ 375
Query: 162 EKQKEKKRRAEEDLTFEE 179
+ ++E++ R E+ L E+
Sbjct: 376 QLRREQQLRREQQLRREQ 393
Score = 29.6 bits (65), Expect = 1.8
Identities = 17/80 (21%), Positives = 47/80 (58%), Gaps = 6/80 (7%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
++ +R R ++ +Q ++R + +++ EE+++ E++++ +EEE + + ++
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERR----EQQLRREQEEERREQQLRR 379
Query: 162 EKQ--KEKKRRAEEDLTFEE 179
E+Q +E++ R E+ L E+
Sbjct: 380 EQQLRREQQLRREQQLRREQ 399
Score = 29.6 bits (65), Expect = 1.8
Identities = 15/65 (23%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK---QKEKKRRAEEDLT 176
++ +K E ++ +E+ + + EE++ + REE++ + + K ++++ RR E D
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 177 FEEDD 181
F E +
Sbjct: 1503 FREQE 1507
Score = 29.3 bits (64), Expect = 2.3
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 127 EVNKKKMEEKQ----KDYDFEERMKE--LREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
E +++ EE+Q K ++ EE E LR E K ++K+++RR +D F+E+
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 181 DE 182
+E
Sbjct: 242 EE 243
Score = 28.9 bits (63), Expect = 3.0
Identities = 13/58 (22%), Positives = 37/58 (63%), Gaps = 3/58 (5%)
Query: 120 DQVKK--RFEVNKKKMEEKQKDYDFE-ERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
+Q++K R E+ +++ EE+Q+ E+ ++EEE+ + ++ ++++++R +E+
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Score = 28.5 bits (62), Expect = 3.9
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 14/83 (16%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELRE------EEEKAKAYKKEKQK 165
+R ER +Q +R E ++K EE+Q + EE+ +E EEE+ + ++E+Q
Sbjct: 1755 LRPERE--EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 166 EKKRR------AEEDLTFEEDDE 182
++R EE L EE ++
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQ 1835
Score = 27.7 bits (60), Expect = 6.7
Identities = 16/63 (25%), Positives = 38/63 (60%), Gaps = 5/63 (7%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEE 179
+Q +R E +K ++E+Q+ +ER ++LR++ ++ K +++++ R E D F E
Sbjct: 1380 EQRLRRQERERKFLKEEQQ-LRCQEREQQLRQDRDR----KFREEEQQLSRQERDRKFRE 1434
Query: 180 DDE 182
+++
Sbjct: 1435 EEQ 1437
Score = 27.7 bits (60), Expect = 6.7
Identities = 15/64 (23%), Positives = 39/64 (60%), Gaps = 5/64 (7%)
Query: 124 KRFEVNKKKMEEKQKDY-DFEERMKELREEEEKAKAYKKEKQ----KEKKRRAEEDLTFE 178
++F +++ ++E+++ +ER ++ EEE + + ++E+Q +++K R EE L E
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 179 EDDE 182
+++
Sbjct: 1679 GEEQ 1682
Score = 27.3 bits (59), Expect = 8.8
Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 6/72 (8%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQ-----KEKKR 169
+R ++ + E +K +EE+Q+ +ER ++ +EE++ + ++E+Q K R
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQR-LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 170 RAEEDLTFEEDD 181
E+ L+ +E D
Sbjct: 1418 EEEQQLSRQERD 1429
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 42.4 bits (98), Expect = 3e-04
Identities = 24/87 (27%), Positives = 53/87 (60%), Gaps = 5/87 (5%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERM----KELREEEEKAK 157
+K Q R E +Q +K + +K E+++K + EE+M +++RE+EEK +
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 158 AYKKE-KQKEKKRRAEEDLTFEEDDEM 183
+++ +++E+K R +E++T E++++M
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKM 649
Score = 39.3 bits (90), Expect = 0.002
Identities = 22/69 (31%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E T +Q +K E +K E+++K + EE M R+EE+ + KK +++E+K R +E+
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM--WRQEEKIREQEKKIREQEEKIREQEE 696
Query: 175 LTFEEDDEM 183
+ E++++M
Sbjct: 697 MMQEQEEKM 705
Score = 38.1 bits (87), Expect = 0.005
Identities = 38/166 (22%), Positives = 76/166 (45%), Gaps = 17/166 (10%)
Query: 16 WDKDEYEKLAEKRLTEEREK--KDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTP 73
W ++E + E++ E+ EK K + ++ + ++ + + E K+ + +T+
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ- 645
Query: 74 QSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKM 133
+ +MG +C+ +K Q R E +Q KK E +K
Sbjct: 646 EEKMGEQEEKMCE-------------QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR 692
Query: 134 EEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEE 179
E+++ + EE+M E +EE+ + K ++Q+EK RR EE + +E
Sbjct: 693 EQEEMMQEQEEKMWE-QEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 37.4 bits (85), Expect = 0.008
Identities = 20/74 (27%), Positives = 44/74 (59%), Gaps = 4/74 (5%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE----LREEEEKAKAYKKEKQKEKK 168
R E +Q +KR E +K ++++K + EE+++E +RE+EEK + ++ Q++++
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Query: 169 RRAEEDLTFEEDDE 182
+ E++ E +E
Sbjct: 648 KMGEQEEKMCEQEE 661
Score = 36.2 bits (82), Expect = 0.019
Identities = 24/92 (26%), Positives = 52/92 (56%), Gaps = 14/92 (15%)
Query: 106 RNLGMSMRVERSTLDQVKKRFEVNK-----KKMEEKQKDYDFEERMKE----LREEEEKA 156
R L M + +Q +KR E K K+ E++ K + EE+++E +RE+E+K
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 157 -----KAYKKEKQKEKKRRAEEDLTFEEDDEM 183
K +++EK +E+++R E++ + +++++
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Score = 35.0 bits (79), Expect = 0.042
Identities = 20/75 (26%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELRE---EEEKAKA 158
+K +R M E Q + +E +K +++ ++ EE+++EL E E+EK +
Sbjct: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 159 YKKEKQKEKKRRAEE 173
++++Q+E+K R +E
Sbjct: 409 QEEKRQEEEKIREQE 423
Score = 35.0 bits (79), Expect = 0.042
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKK--KMEEKQKDYDFEERMKELREEEEKAKAY 159
+K +R M E Q + +E +K ++EEK + + +E R+EEEK +
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 160 KKEKQKEKKRRAEEDLTFEEDDEM 183
+K +++E K +E+ E+++++
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKI 446
Score = 33.9 bits (76), Expect = 0.094
Identities = 24/100 (24%), Positives = 56/100 (56%), Gaps = 15/100 (15%)
Query: 97 DHINGKKHQRNLGMSMRVERSTL------DQVKKRFEVNKKKMEEKQKDYDFEERMKE-- 148
DH+ + + + +VE + L Q +K + +K E ++K + EE+++E
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 149 --LREEEEKAKAYKK---EKQKEKKRRAEEDLTFEEDDEM 183
+RE+EEK + ++ EK+++ +R +E++ +E++++M
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRR--QEEMMWEKEEKM 365
Score = 33.9 bits (76), Expect = 0.094
Identities = 38/173 (21%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 18 KDEYEKLAEKRLTEEREKKDGKPVQPVKR--ELLRHRDYKV-DLESKLGKTIVITKTTPQ 74
+ E EK+ E+ +E+E K + + ++ E +R ++ K+ E K+ + I + +
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472
Query: 75 SEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKME 134
E + ++ I+ + I +K + + E Q +K + +K E
Sbjct: 473 QEQEEMWRQ------EEKIHEQEEIWRQKEKMH-----EQEEKIRKQEEKVWRQEEKIRE 521
Query: 135 EKQKDYDFEERM----KELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
+++K + EE+M +++RE+EE + ++EK E+++ EE+ E++D+M
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWR--EEEKMHEQEKIWEEEKRQEQEDKM 572
Score = 33.9 bits (76), Expect = 0.094
Identities = 16/72 (22%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE----LREEEEKAKAYKKEKQKEKKRR 170
E +Q +K ++ +K E+++K + EE+++E +RE+EE + +++ +++++
Sbjct: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
Query: 171 AEEDLTFEEDDE 182
E++ +E +E
Sbjct: 657 CEQEEKMQEQEE 668
Score = 32.3 bits (72), Expect = 0.27
Identities = 16/65 (24%), Positives = 43/65 (66%), Gaps = 11/65 (16%)
Query: 130 KKKMEEKQKDYDFEERMKE----------LREEEEKA-KAYKKEKQKEKKRRAEEDLTFE 178
++KM E++K ++ E+R ++ +RE+EEK + +K +++E+KR+ +E+ ++
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 179 EDDEM 183
+++++
Sbjct: 610 QEEKI 614
Score = 31.6 bits (70), Expect = 0.47
Identities = 16/69 (23%), Positives = 39/69 (56%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
M+ + T+ + +++ +KK+ E+++ +E M + +EE+ + K +Q+EK +
Sbjct: 663 MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722
Query: 172 EEDLTFEED 180
EE + +E+
Sbjct: 723 EEKMRRQEE 731
Score = 30.8 bits (68), Expect = 0.79
Identities = 20/85 (23%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+K +R M E + +K E K + +E+++ + + R +E R+E+E AK +++
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE-AKMWRQ 435
Query: 162 E---KQKEKKRRAEEDLTFEEDDEM 183
E +++E+K R +E + +++++
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKI 460
Score = 30.8 bits (68), Expect = 0.79
Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 7/69 (10%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKEL---REEEEKAKAYKKEKQKEKKRRA 171
E +Q K + +K E+++K + EE+++E R+E+E+ K KQ+EK R
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE----KMWKQEEKIREQ 617
Query: 172 EEDLTFEED 180
EE + +E+
Sbjct: 618 EEKIQEQEE 626
Score = 30.4 bits (67), Expect = 1.0
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 9/70 (12%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERM----KELREEEEKAKAYKKEKQKEKKRR 170
E+ + + +KR E K +++K + EE++ +++RE+EEK +++Q+EK +
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK-----RQEQEEKMWK 609
Query: 171 AEEDLTFEED 180
EE + +E+
Sbjct: 610 QEEKIREQEE 619
Score = 30.4 bits (67), Expect = 1.0
Identities = 17/84 (20%), Positives = 43/84 (51%), Gaps = 11/84 (13%)
Query: 110 MSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE-----------LREEEEKAKA 158
M+ E +Q +K E +K E+++ + EE+++E +RE+EE +
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700
Query: 159 YKKEKQKEKKRRAEEDLTFEEDDE 182
+++ +++++ E++ +E +E
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEE 724
Score = 29.3 bits (64), Expect = 2.3
Identities = 19/75 (25%), Positives = 41/75 (54%), Gaps = 7/75 (9%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQ------KEKK 168
E +Q +K E +K +++ ++ EE+M+ +EE K K +Q KE+K
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 169 RRAEEDLTFEEDDEM 183
R +E++ +E+++++
Sbjct: 379 MRRQEEMMWEKEEKI 393
Score = 28.1 bits (61), Expect = 5.1
Identities = 15/73 (20%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK----QKEK 167
+R + + + +++ ++ E++K ++ E+ +E + +E++ K +++E+ Q+EK
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 168 KRRAEEDLTFEED 180
R EE + +E+
Sbjct: 586 VWRQEEKIREQEE 598
Score = 27.7 bits (60), Expect = 6.7
Identities = 19/74 (25%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREE--EEKAKAYKKEK---QKEKKR 169
E +Q +K E +K E+++ + EE+M E E+ E++ K ++E+ ++E+K
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 170 RAEEDLTFEEDDEM 183
R +E E+++++
Sbjct: 678 REQEKKIREQEEKI 691
>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
sapiens]
Length = 558
Score = 42.4 bits (98), Expect = 3e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 11/157 (7%)
Query: 18 KDEYEKLAEKRLTEEREKKDGK------PVQPVKRELLRHRDYKVDLESKLGKTIVITKT 71
K E EK EK++ ERE + G+ V ++ L+ R + + E +
Sbjct: 115 KKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDV 174
Query: 72 TPQSEMGGYYCNVCDCVVKD----SINFLDHINGKKHQRNLGMSMRV-ERSTLDQVKKRF 126
T Q ++ G+Y ++ + V + +F + +G K +++ G S V ++ + Q K
Sbjct: 175 TKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCIL 234
Query: 127 EVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEK 163
+ + K E D DF+ + E EE ++EK
Sbjct: 235 QTDVKVEENPDADSDFDAKSSADDEIEETRVNCRREK 271
Score = 36.6 bits (83), Expect = 0.014
Identities = 25/85 (29%), Positives = 49/85 (57%), Gaps = 6/85 (7%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEE----RMKELREEEEKAK 157
K+H++ R +R D+V KR E +++K +++++ D ++ R E E+EEK+K
Sbjct: 357 KRHEQEDKPRARDQRERSDRVWKR-EKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSK 415
Query: 158 AYKKEKQKEKKRRAEEDLTFEEDDE 182
A K+E K +K R E + + + ++
Sbjct: 416 A-KEEHMKVRKERYENNDKYRDREK 439
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 42.4 bits (98), Expect = 3e-04
Identities = 49/208 (23%), Positives = 95/208 (45%), Gaps = 19/208 (9%)
Query: 6 GTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKT 65
GTK R K +D+ ++ + +E+ KKD +P + VK + R + + +++S+ G+
Sbjct: 206 GTKVQAKREKLQEDK-PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF-TEVKSQNGEF 263
Query: 66 IVI----TKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST--- 118
+ T+ T G + + + + + +R S E+
Sbjct: 264 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ 323
Query: 119 ------LDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
L+++KK+ E +K +EE+++ EE ++LREEEEK + K+E ++ + AE
Sbjct: 324 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAE 382
Query: 173 EDLTFEED---DEMAAVMGFSGFGSTKK 197
+ ED D+ F+ GS+ K
Sbjct: 383 KRQKMPEDGLSDDKKPFKCFTPKGSSLK 410
Score = 34.7 bits (78), Expect = 0.055
Identities = 34/181 (18%), Positives = 74/181 (40%), Gaps = 12/181 (6%)
Query: 23 KLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGGYYC 82
++A +R ++ E+ + + ++E LR + + L + V + + E
Sbjct: 18 QIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT 77
Query: 83 NVCDCVVKDSINFLDHINGKKHQRNLGMSMRVER----------STLDQVKKRFEVNKKK 132
D FL+ + ++ +R + +ER ++L +R + + +
Sbjct: 78 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 137
Query: 133 MEEKQKDYDFEERMK--ELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVMGFS 190
E +K+ E R + E+ E E K+Y+K ++ + +ED EE++E G
Sbjct: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
Query: 191 G 191
G
Sbjct: 198 G 198
Score = 29.6 bits (65), Expect = 1.8
Identities = 21/88 (23%), Positives = 46/88 (52%), Gaps = 10/88 (11%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVN------KKKMEEKQKDYDFEERMK--ELREEE 153
+K +++ R E + V K ++ N + K E+K+K+ + EE+ K + E +
Sbjct: 142 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 201
Query: 154 EKAKAYKKEKQKEKKRRAEEDLTFEEDD 181
+ K K + ++EK + E+ TF++++
Sbjct: 202 GEEKGTKVQAKREKLQ--EDKPTFKKEE 227
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 42.4 bits (98), Expect = 3e-04
Identities = 49/208 (23%), Positives = 95/208 (45%), Gaps = 19/208 (9%)
Query: 6 GTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKT 65
GTK R K +D+ ++ + +E+ KKD +P + VK + R + + +++S+ G+
Sbjct: 212 GTKVQAKREKLQEDK-PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF-TEVKSQNGEF 269
Query: 66 IVI----TKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST--- 118
+ T+ T G + + + + + +R S E+
Sbjct: 270 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ 329
Query: 119 ------LDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
L+++KK+ E +K +EE+++ EE ++LREEEEK + K+E ++ + AE
Sbjct: 330 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAE 388
Query: 173 EDLTFEED---DEMAAVMGFSGFGSTKK 197
+ ED D+ F+ GS+ K
Sbjct: 389 KRQKMPEDGLSDDKKPFKCFTPKGSSLK 416
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/184 (19%), Positives = 76/184 (41%), Gaps = 12/184 (6%)
Query: 20 EYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGG 79
E E++A +R ++ E+ + + ++E LR + + L + V + + E
Sbjct: 21 EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAK 80
Query: 80 YYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVER----------STLDQVKKRFEVN 129
D FL+ + ++ +R + +ER ++L +R + +
Sbjct: 81 TTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQND 140
Query: 130 KKKMEEKQKDYDFEERMK--ELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVM 187
+ E +K+ E R + E+ E E K+Y+K ++ + +ED EE++E
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 188 GFSG 191
G G
Sbjct: 201 GSIG 204
Score = 29.6 bits (65), Expect = 1.8
Identities = 21/88 (23%), Positives = 46/88 (52%), Gaps = 10/88 (11%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVN------KKKMEEKQKDYDFEERMK--ELREEE 153
+K +++ R E + V K ++ N + K E+K+K+ + EE+ K + E +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 207
Query: 154 EKAKAYKKEKQKEKKRRAEEDLTFEEDD 181
+ K K + ++EK + E+ TF++++
Sbjct: 208 GEEKGTKVQAKREKLQ--EDKPTFKKEE 233
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 42.4 bits (98), Expect = 3e-04
Identities = 49/208 (23%), Positives = 95/208 (45%), Gaps = 19/208 (9%)
Query: 6 GTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKT 65
GTK R K +D+ ++ + +E+ KKD +P + VK + R + + +++S+ G+
Sbjct: 441 GTKVQAKREKLQEDK-PTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF-TEVKSQNGEF 498
Query: 66 IVI----TKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST--- 118
+ T+ T G + + + + + +R S E+
Sbjct: 499 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ 558
Query: 119 ------LDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
L+++KK+ E +K +EE+++ EE ++LREEEEK + K+E ++ + AE
Sbjct: 559 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-RRLKEEIERRRAEAAE 617
Query: 173 EDLTFEED---DEMAAVMGFSGFGSTKK 197
+ ED D+ F+ GS+ K
Sbjct: 618 KRQKMPEDGLSDDKKPFKCFTPKGSSLK 645
Score = 40.4 bits (93), Expect = 0.001
Identities = 43/198 (21%), Positives = 91/198 (45%), Gaps = 40/198 (20%)
Query: 14 RKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGK----TIVIT 69
+ + K+++ AE+ E++EK++ + +P KR + +V +E K + T+V++
Sbjct: 170 KSYQKNDWRD-AEENKKEDKEKEEEEEEKP-KRGSIGENQVEVMVEEKTTESQEETVVMS 227
Query: 70 -----------KTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST 118
K + E G D I+ + + + +R R+E
Sbjct: 228 LKNGQISSEEPKQEEEREQGS-----------DEISHHEKMEEEDKERAEAERARLEAEE 276
Query: 119 LDQVKK-----------RFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEK 167
+++K R E +K ++++ + EER + +REEE++A ++ ++E+
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEER-ERMREEEKRAAEERQRIKEEE 335
Query: 168 KRRAEEDLTFEEDDEMAA 185
KR AEE +E+++ AA
Sbjct: 336 KRAAEERQRIKEEEKRAA 353
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/184 (19%), Positives = 76/184 (41%), Gaps = 12/184 (6%)
Query: 20 EYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEMGG 79
E E++A +R ++ E+ + + ++E LR + + L + V + + E
Sbjct: 21 EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAK 80
Query: 80 YYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVER----------STLDQVKKRFEVN 129
D FL+ + ++ +R + +ER ++L +R + +
Sbjct: 81 TTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQND 140
Query: 130 KKKMEEKQKDYDFEERMK--ELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAAVM 187
+ E +K+ E R + E+ E E K+Y+K ++ + +ED EE++E
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 188 GFSG 191
G G
Sbjct: 201 GSIG 204
Score = 37.4 bits (85), Expect = 0.008
Identities = 20/74 (27%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Query: 112 MRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRA 171
+ E Q ++R E +++ +++ EER + ++EEE++A ++ ++E+KR A
Sbjct: 295 IEAEEKAAAQERERREAEERERMREEEKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAA 353
Query: 172 EEDLTFEEDDEMAA 185
EE +E+++ AA
Sbjct: 354 EERQRIKEEEKRAA 367
Score = 37.4 bits (85), Expect = 0.008
Identities = 22/62 (35%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKA--YKKEKQKEKKRRAE 172
ER + + +KR +++++E++K EER + EEEEKAK K+ KQ E+K+ A
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAA-EERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399
Query: 173 ED 174
++
Sbjct: 400 QE 401
Score = 36.2 bits (82), Expect = 0.019
Identities = 22/75 (29%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE----LREEEEKAKAYKKEKQKEKKRR 170
ER ++ ++ E K+ EE+Q+ + E+R E ++EEE++A ++ ++E+KR
Sbjct: 307 ERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 366
Query: 171 AEEDLTFEEDDEMAA 185
AEE ++E A
Sbjct: 367 AEERQRARAEEEEKA 381
Score = 34.3 bits (77), Expect = 0.072
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
ER + + +KR +++++E++K EER + EE+ A+ ++ K++EK+ E
Sbjct: 313 ERERMREEEKRAAEERQRIKEEEKRAA-EERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371
Query: 175 LTFEEDDEMAAV 186
E++E A V
Sbjct: 372 RARAEEEEKAKV 383
Score = 31.2 bits (69), Expect = 0.61
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Query: 112 MRVERSTLDQVKKRF-EVNKKKMEEKQKDYDFEERMKELRE---EEEKAKAYKKEK---Q 164
MR E + ++R E K+ EE+Q+ + E+R E R+ EEEK A ++++ +
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAE 376
Query: 165 KEKKRRAEEDLTFEEDDEMAAVM 187
+E+K + EE ++ +E M
Sbjct: 377 EEEKAKVEEQKRNKQLEEKKHAM 399
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 42.0 bits (97), Expect = 3e-04
Identities = 25/100 (25%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
Query: 88 VVKDSINFLDHINGKKHQRNLGMSM------RVERSTLDQVKKRFEVNKKKME-EKQKDY 140
+ K+ IN ++ K+ + +S ++E + K+R E+ K++ E E++++
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERER 318
Query: 141 DFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
+ E R +E E E+ + +KE+++E++R + D T E D
Sbjct: 319 ERERREREREREREREREKEKERERERERDRDRDRTKERD 358
Score = 37.0 bits (84), Expect = 0.011
Identities = 34/164 (20%), Positives = 78/164 (47%), Gaps = 10/164 (6%)
Query: 18 KDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSEM 77
+D ++KL E++ +E+E+++ ++ +RE R R+ + + + + + + E
Sbjct: 285 RDTHKKLEEEKGKKEKERQE---IEKERRERERERERERERREREREREREREREKEKER 341
Query: 78 GGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQ 137
D +D D ++ R+ +R+ + ++++ E++
Sbjct: 342 ERERERDRD---RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
Query: 138 KDYDFE-ERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
++ + E ER +E E E+ + ++E++K+KKR EED EED
Sbjct: 399 REREREREREREREREREREREREREREKDKKRDREED---EED 439
Score = 34.7 bits (78), Expect = 0.055
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 32/177 (18%)
Query: 8 KNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIV 67
KN + R + EYEK AE+ EER ++ K + +K L + D + D + G +
Sbjct: 462 KNWEIRERKKTREYEKEAERE--EERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQ 519
Query: 68 ITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRF- 126
+ EM D + K+ E+ L+++++R
Sbjct: 520 KRLRDREKEMEA-----------------DERDRKR-----------EKEELEEIRQRLL 551
Query: 127 -EVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
E + E Q+ ER ++ + ++E ++E+++EK+ + EE + EE+ E
Sbjct: 552 AEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
Score = 31.6 bits (70), Expect = 0.47
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMK--ELREEEEKAKAY 159
KK R ER L+ ++ + +E+ K+++ ER K E +E E+ +
Sbjct: 429 KKRDREEDEEDAYERRKLE---RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Query: 160 KKEKQKEKKRRAE--EDLTFEEDD 181
++E KE KR E ED + DD
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDD 509
Score = 30.4 bits (67), Expect = 1.0
Identities = 17/66 (25%), Positives = 37/66 (56%), Gaps = 6/66 (9%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFE---ERMKELREEEEKAKAYKKEKQKEKKRRAEEDLT 176
D+ K+R ++ + E+ +D D E +R K+ EK++ ++E+++E++R E +
Sbjct: 352 DRTKER---DRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 177 FEEDDE 182
E + E
Sbjct: 409 RERERE 414
Score = 30.0 bits (66), Expect = 1.4
Identities = 34/159 (21%), Positives = 71/159 (44%), Gaps = 2/159 (1%)
Query: 15 KWDKDEYEKLAEKRLTE-EREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTP 73
K +K+ E E+R E ERE++ + + +RE R R+ + + E + + +T
Sbjct: 297 KKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKE 356
Query: 74 QSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKM 133
+ + + S D ++ R+ ER + ++ E +++
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE 416
Query: 134 EEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
E++++ + E+ K REE+E+ AY++ K + K R E
Sbjct: 417 REREREREREKDKKRDREEDEE-DAYERRKLERKLREKE 454
Score = 27.3 bits (59), Expect = 8.8
Identities = 28/170 (16%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 3 SGSGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKL 62
S S K+ D R+ +++ + +R E +++ + + +RE + RD + D E
Sbjct: 382 SRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAY 441
Query: 63 GKTIVITKTTPQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQV 122
+ + K + + Y + + +++ ++ + + M E L +
Sbjct: 442 ERRKLERKL--REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEF 499
Query: 123 KKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
+ ++ ++ + K Y K LR+ E++ +A ++++++EK+ E
Sbjct: 500 LEDYDDDR----DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE 545
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 42.0 bits (97), Expect = 3e-04
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 8/162 (4%)
Query: 19 DEYEKLAEKRLTE---EREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQS 75
D+Y KL E+R E++K+ K + K+ RH + + + + T +
Sbjct: 722 DQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEM 781
Query: 76 EMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEV-----NK 130
+ D D LD K + + ++ R+T +V
Sbjct: 782 PENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKS 841
Query: 131 KKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
KK ++K+K + +ER KE ++E+EK K+ K +K+K +K + E
Sbjct: 842 KKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEE 883
Score = 31.2 bits (69), Expect = 0.61
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Query: 144 ERMKELREEEEKAKAYKKEKQKEKK-RRAEEDLTFEEDDEMA 184
E + R++ EK K KK K+KEKK +R L E D+++A
Sbjct: 728 EEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIA 769
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 42.0 bits (97), Expect = 3e-04
Identities = 22/69 (31%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 115 ERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEED 174
E T +Q +K E +K E+++K + EE+M+ R+EE+ + KK +++E+K R +E+
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR--RQEEKIREQEKKIREQEEKIREQEE 662
Query: 175 LTFEEDDEM 183
+ E++++M
Sbjct: 663 MMQEQEEKM 671
Score = 37.7 bits (86), Expect = 0.006
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 14/92 (15%)
Query: 106 RNLGMSMRVERSTLDQVKKRFEVNK-----KKMEEKQKDYDFEERMKE----LREEEEK- 155
R L M + +Q +KR E K K+ E++ K + EE+++E +RE+EEK
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 156 ----AKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
K +++EK +E+++R E++ + +++++
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 532
Score = 37.4 bits (85), Expect = 0.008
Identities = 40/167 (23%), Positives = 77/167 (46%), Gaps = 22/167 (13%)
Query: 14 RKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKV-DLESKLGKTIVITKTT 72
+ W ++E E+++ E+ EK + E +R ++ K+ + E K+ + +T+
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQ------EEKIREQEEKIREQEEKIREQEEMTQEQ 611
Query: 73 PQSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKK 132
+ +MG +C+ +K Q R E +Q KK E +K
Sbjct: 612 -EEKMGEQEEKMCE-------------QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 133 MEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEE 179
E+++ + EE+M E +EE+ + K ++Q+EK RR EE + +E
Sbjct: 658 REQEEMMQEQEEKMWE-QEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Score = 37.0 bits (84), Expect = 0.011
Identities = 19/69 (27%), Positives = 45/69 (65%), Gaps = 5/69 (7%)
Query: 120 DQVKKRFEVNKKKMEEKQKDYDFEERMKEL-----REEEEKAKAYKKEKQKEKKRRAEED 174
+Q +K + +K +++K +D EE+++E R+EE+ + +K +++E+K R +E+
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Query: 175 LTFEEDDEM 183
+T E++++M
Sbjct: 607 MTQEQEEKM 615
Score = 35.4 bits (80), Expect = 0.032
Identities = 34/173 (19%), Positives = 80/173 (46%), Gaps = 20/173 (11%)
Query: 14 RKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTP 73
+ W ++E + E+++ E+ EK + + ++E +R + + + E + K
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE---EKIRE 534
Query: 74 QSEMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKM 133
Q E+ K+ I H +K ++ R E DQ +K E +K
Sbjct: 535 QEEIWRQ---------KEKI----HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 134 EEKQKDYDFEERMKE----LREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
+++K + EE+++E +RE+EE + +++ +++++ E++ +E +E
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Score = 35.0 bits (79), Expect = 0.042
Identities = 20/75 (26%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELRE---EEEKAKA 158
+K +R M E Q + +E +K +++ ++ EE+++EL E E+EK +
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 159 YKKEKQKEKKRRAEE 173
++++Q+E+K R +E
Sbjct: 456 QEEKRQEEEKIREQE 470
Score = 35.0 bits (79), Expect = 0.042
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKK--KMEEKQKDYDFEERMKELREEEEKAKAY 159
+K +R M E Q + +E +K ++EEK + + +E R+EEEK +
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 160 KKEKQKEKKRRAEEDLTFEEDDEM 183
+K +++E K +E+ E+++++
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKI 493
Score = 33.9 bits (76), Expect = 0.094
Identities = 24/100 (24%), Positives = 56/100 (56%), Gaps = 15/100 (15%)
Query: 97 DHINGKKHQRNLGMSMRVERSTL------DQVKKRFEVNKKKMEEKQKDYDFEERMKE-- 148
DH+ + + + +VE + L Q +K + +K E ++K + EE+++E
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 149 --LREEEEKAKAYKK---EKQKEKKRRAEEDLTFEEDDEM 183
+RE+EEK + ++ EK+++ +R +E++ +E++++M
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRR--QEEMMWEKEEKM 426
Score = 33.1 bits (74), Expect = 0.16
Identities = 19/64 (29%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKE-LREEEEKAKAYKKEKQKEKKRRAEEDLTFEE 179
Q +K E K + EEK+++ + R +E +RE+EE + +K ++E+K R +E+ + +
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 180 DDEM 183
+++M
Sbjct: 563 EEKM 566
Score = 32.0 bits (71), Expect = 0.36
Identities = 23/83 (27%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+K +R M E + +K E K + +E+++ + + R +E R+E+E AK +++
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE-AKMWRQ 482
Query: 162 E----KQKEKKRRAEEDLTFEED 180
E +Q+EK R EE + +E+
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEE 505
Score = 31.2 bits (69), Expect = 0.61
Identities = 18/84 (21%), Positives = 43/84 (51%), Gaps = 11/84 (13%)
Query: 110 MSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKE-----------LREEEEKAKA 158
M+ E +Q +K E +K E+++K EE+++E +RE+EE +
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Query: 159 YKKEKQKEKKRRAEEDLTFEEDDE 182
+++ +++++ E++ +E +E
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEE 690
Score = 30.8 bits (68), Expect = 0.79
Identities = 20/76 (26%), Positives = 41/76 (53%), Gaps = 5/76 (6%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELRE-----EEEKAKAYKKEKQKEK 167
R E +Q +K E +K E+++ + EE+M E E EE+ + +K +++E+
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 168 KRRAEEDLTFEEDDEM 183
K R +E E+++++
Sbjct: 642 KIREQEKKIREQEEKI 657
Score = 29.6 bits (65), Expect = 1.8
Identities = 34/171 (19%), Positives = 81/171 (47%), Gaps = 20/171 (11%)
Query: 16 WDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQS 75
W+K+E + E+++ E+EK + + + E +R ++ + + E+K+ + K Q
Sbjct: 434 WEKEEKIRELEEKM-HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE--EKIREQE 490
Query: 76 EMGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKK-RFEVNKKKME 134
E +++ + K H++ +R E +Q + R E ++ E
Sbjct: 491 EK-----------IREQEEKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIREQE 536
Query: 135 E--KQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEM 183
E +QK+ E+ K ++EE+ + +K +E+K R +E+ + +++++
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 42.0 bits (97), Expect = 3e-04
Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
Query: 90 KDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKEL 149
K +I F + G+ +R + + E+ ++ KK+ E KKK EE++++ + E R EL
Sbjct: 790 KAAIVFQKQLRGQIARR-VYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAEL 848
Query: 150 REEEEKAKAYKKEKQKEKKRRAEEDLTFE 178
R ++E+ ++E + +K + E +LT E
Sbjct: 849 RAQQEEETRKQQELEALQKSQKEAELTRE 877
Score = 35.0 bits (79), Expect = 0.042
Identities = 26/102 (25%), Positives = 55/102 (53%), Gaps = 8/102 (7%)
Query: 81 YCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDY 140
Y V CVV N+ + ++ ++ ++ Q+ +R V ++ + EK+
Sbjct: 762 YRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARR--VYRQLLAEKR--- 816
Query: 141 DFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDE 182
E+ K+ +EEEEK K ++E+++E++RR E +L ++++E
Sbjct: 817 --EQEEKKKQEEEEKKKREEEERERERERR-EAELRAQQEEE 855
Score = 32.7 bits (73), Expect = 0.21
Identities = 19/66 (28%), Positives = 39/66 (59%), Gaps = 6/66 (9%)
Query: 121 QVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEED 180
+V ++ K++ EEK+K EE K+ REEEE+ + + +++E + RA+++ +
Sbjct: 806 RVYRQLLAEKREQEEKKKQ---EEEEKKKREEEERER---ERERREAELRAQQEEETRKQ 859
Query: 181 DEMAAV 186
E+ A+
Sbjct: 860 QELEAL 865
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 42.0 bits (97), Expect = 3e-04
Identities = 18/68 (26%), Positives = 43/68 (63%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
R ER L + ++R E+ ++K+E ++ + + ER + E+E + +A + +++E+ RR +
Sbjct: 636 REERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQ 695
Query: 173 EDLTFEED 180
+ L +E++
Sbjct: 696 QQLRYEQE 703
Score = 30.8 bits (68), Expect = 0.79
Identities = 15/59 (25%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEK--QKDYDFEERMKELREEEEKAKAYKKEKQKEKKR 169
R+ER L++ + R E ++K E+ ++ + + ++LR E+EK + K+ + + +R
Sbjct: 660 RMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRR 718
Score = 29.3 bits (64), Expect = 2.3
Identities = 44/201 (21%), Positives = 81/201 (40%), Gaps = 31/201 (15%)
Query: 5 SGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVK--------------RELLR 50
SG K R K EKR +E+ EKK+ K + ++ E ++
Sbjct: 464 SGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIK 523
Query: 51 HRDYKVDLESKLGKTIVITKTTP----QSEMGGYYCNVCDCVVKDSINFLDHINGKKHQR 106
+ K + SK +VI T + G Y + + LD K ++R
Sbjct: 524 KSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRR 583
Query: 107 NLGMSM-RVERSTLDQVKKRFEVNKKKMEEKQKDYDFE------ERMKELREEEEKAKAY 159
+ +++ L + RFE ++ ME +++ E ER++ +RE EE+ +
Sbjct: 584 KEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQ 643
Query: 160 KK------EKQKEKKRRAEED 174
++ E+QK ++ R E +
Sbjct: 644 RERERLEIERQKLERERMERE 664
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 42.0 bits (97), Expect = 3e-04
Identities = 18/68 (26%), Positives = 43/68 (63%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAE 172
R ER L + ++R E+ ++K+E ++ + + ER + E+E + +A + +++E+ RR +
Sbjct: 654 REERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQ 713
Query: 173 EDLTFEED 180
+ L +E++
Sbjct: 714 QQLRYEQE 721
Score = 30.8 bits (68), Expect = 0.79
Identities = 15/59 (25%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
Query: 113 RVERSTLDQVKKRFEVNKKKMEEK--QKDYDFEERMKELREEEEKAKAYKKEKQKEKKR 169
R+ER L++ + R E ++K E+ ++ + + ++LR E+EK + K+ + + +R
Sbjct: 678 RMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRYEQEKRNSLKRPRDVDHRR 736
Score = 29.3 bits (64), Expect = 2.3
Identities = 44/201 (21%), Positives = 81/201 (40%), Gaps = 31/201 (15%)
Query: 5 SGTKNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVK--------------RELLR 50
SG K R K EKR +E+ EKK+ K + ++ E ++
Sbjct: 482 SGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIK 541
Query: 51 HRDYKVDLESKLGKTIVITKTTP----QSEMGGYYCNVCDCVVKDSINFLDHINGKKHQR 106
+ K + SK +VI T + G Y + + LD K ++R
Sbjct: 542 KSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDKDYRR 601
Query: 107 NLGMSM-RVERSTLDQVKKRFEVNKKKMEEKQKDYDFE------ERMKELREEEEKAKAY 159
+ +++ L + RFE ++ ME +++ E ER++ +RE EE+ +
Sbjct: 602 KEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQ 661
Query: 160 KK------EKQKEKKRRAEED 174
++ E+QK ++ R E +
Sbjct: 662 RERERLEIERQKLERERMERE 682
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 42.0 bits (97), Expect = 3e-04
Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 20/100 (20%)
Query: 102 KKHQRNLG--MSMRVERSTLDQVK---KRFEVNKKKMEEKQKDYDFEERMKELREEEEKA 156
++ Q LG + +R ER +++K KR + KK +E++K+ +ER +E RE++EK
Sbjct: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER-REKREKDEKE 396
Query: 157 KAYK--------KEKQK------EKKRRAEEDLTFEEDDE 182
KA K KE+Q+ E+KR+ EE+ E+++
Sbjct: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
Score = 37.4 bits (85), Expect = 0.008
Identities = 21/71 (29%), Positives = 38/71 (53%)
Query: 111 SMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRR 170
S + R T VK E NK +++ Q+ + +++ REE+EK K K ++E K++
Sbjct: 315 STPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKK 374
Query: 171 AEEDLTFEEDD 181
EE+ +E +
Sbjct: 375 KEEEKELKEKE 385
Score = 34.3 bits (77), Expect = 0.072
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 8/78 (10%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+K +++ +R ++ K+R E + K+EEK+K +E K LREEE++ KA K
Sbjct: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRK----KEEEKRLREEEKRIKAEKA 443
Query: 162 E----KQKEKKRRAEEDL 175
E QK K +A + L
Sbjct: 444 EITRFFQKPKTPQAPKTL 461
Score = 32.7 bits (73), Expect = 0.21
Identities = 19/78 (24%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
K+ ++ L R E+ D+ +K + K+ K++ E +++E R++EE+ K ++
Sbjct: 375 KEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE-KRLRE 433
Query: 162 EKQKEKKRRAEEDLTFEE 179
E+++ K +AE F++
Sbjct: 434 EEKRIKAEKAEITRFFQK 451
Score = 31.6 bits (70), Expect = 0.47
Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 119 LDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKKE-KQKEKKRRAEED 174
L + ++R K E+++ +E K +EE +K K +KE K+KE++ + E+D
Sbjct: 337 LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKD 393
Score = 29.6 bits (65), Expect = 1.8
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 8 KNLDFRRKWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYK 55
K + R K +KDE EK ++RL EER K+ + ++ E + + K
Sbjct: 382 KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429
Score = 27.7 bits (60), Expect = 6.7
Identities = 15/48 (31%), Positives = 28/48 (58%)
Query: 15 KWDKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKL 62
K K+E ++L EK E+REK + + + + + R ++ + LE+KL
Sbjct: 372 KKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 41.6 bits (96), Expect = 4e-04
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 17/94 (18%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+KHQ+ L ER L+ KKR E +++ E+ ++ EE M L++ EEK K ++
Sbjct: 312 EKHQKQL------ERQQLETEKKRRETVEREKEQMMREK--EELMLRLQDYEEKTKKAER 363
Query: 162 E---------KQKEKKRRAEEDLTFEEDDEMAAV 186
E + +E+++RA+E+ E D MAA+
Sbjct: 364 ELSEQIQRALQLEEERKRAQEEAERLEADRMAAL 397
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 41.6 bits (96), Expect = 4e-04
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 17/94 (18%)
Query: 102 KKHQRNLGMSMRVERSTLDQVKKRFEVNKKKMEEKQKDYDFEERMKELREEEEKAKAYKK 161
+KHQ+ L ER L+ KKR E +++ E+ ++ EE M L++ EEK K ++
Sbjct: 312 EKHQKQL------ERQQLETEKKRRETVEREKEQMMREK--EELMLRLQDYEEKTKKAER 363
Query: 162 E---------KQKEKKRRAEEDLTFEEDDEMAAV 186
E + +E+++RA+E+ E D MAA+
Sbjct: 364 ELSEQIQRALQLEEERKRAQEEAERLEADRMAAL 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,687,334
Number of Sequences: 37866
Number of extensions: 386541
Number of successful extensions: 14748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 601
Number of HSP's successfully gapped in prelim test: 520
Number of HSP's that attempted gapping in prelim test: 4925
Number of HSP's gapped (non-prelim): 6048
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.