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Search of human proteins with 21361905
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361905 junctional adhesion molecule 3 precursor [Homo
sapiens]
(355 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 724 0.0
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 186 3e-47
gi|8393638 F11 receptor precursor [Homo sapiens] 162 6e-40
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 88 1e-17
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 80 3e-15
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 70 3e-12
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 67 3e-11
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 64 3e-10
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 64 3e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 61 2e-09
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 59 5e-09
gi|126517478 peroxidasin homolog-like [Homo sapiens] 59 7e-09
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 59 9e-09
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 59 9e-09
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 59 9e-09
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 59 9e-09
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 58 1e-08
gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 58 1e-08
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 58 1e-08
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 57 2e-08
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 57 2e-08
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 57 2e-08
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 57 2e-08
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 57 3e-08
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 57 3e-08
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 57 3e-08
gi|118572606 hemicentin 1 [Homo sapiens] 57 3e-08
gi|15147240 brother of CDO [Homo sapiens] 57 3e-08
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 56 4e-08
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens] 56 6e-08
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 724 bits (1870), Expect = 0.0
Identities = 355/355 (100%), Positives = 355/355 (100%)
Query: 1 MVPARLGPAVAMVTGAGRRVLAGWAHARGDYKPRRAAAGPSATLDMALRRPPRLRLCARL 60
MVPARLGPAVAMVTGAGRRVLAGWAHARGDYKPRRAAAGPSATLDMALRRPPRLRLCARL
Sbjct: 1 MVPARLGPAVAMVTGAGRRVLAGWAHARGDYKPRRAAAGPSATLDMALRRPPRLRLCARL 60
Query: 61 PDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQT 120
PDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQT
Sbjct: 61 PDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQT 120
Query: 121 TYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTV 180
TYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTV
Sbjct: 121 TYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTV 180
Query: 181 QVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSF 240
QVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSF
Sbjct: 181 QVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSF 240
Query: 241 HLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAV 300
HLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAV
Sbjct: 241 HLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAV 300
Query: 301 LALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTDEEGDFRHKSSFVI 355
LALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTDEEGDFRHKSSFVI
Sbjct: 301 LALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTDEEGDFRHKSSFVI 355
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 186 bits (472), Expect = 3e-47
Identities = 101/267 (37%), Positives = 156/267 (58%), Gaps = 11/267 (4%)
Query: 90 EFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWN 149
E++ L+C T +T R+EWKK+ ++V++ +QGD RAE++ +++I N
Sbjct: 42 EYQEAILACK-TPKKTVSSRLEWKKL-GRSVSFVYYQQTLQGDFKNRAEMID-FNIRIKN 98
Query: 150 VTRRDSALYRCEVVARNDR-KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQES 208
VTR D+ YRCEV A +++ + ++E + L V V P P C VP + G + L CQ+
Sbjct: 99 VTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK 158
Query: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
EG+P P Y+W+++ + L + R + NSS+ +N++TGTL F V K D+G+Y C A N
Sbjct: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
Query: 269 DAGSARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYK 328
G RC + M+V DLNI GII V+VV V+++ LG+C A R+GYF S++
Sbjct: 219 SVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKE----TSFQ 274
Query: 329 NPGKPDGVNYIRTDEEGDFRHKSSFVI 355
K + + T E DF+H SF+I
Sbjct: 275 ---KSNSSSKATTMSENDFKHTKSFII 298
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 162 bits (409), Expect = 6e-40
Identities = 99/296 (33%), Positives = 148/296 (50%), Gaps = 14/296 (4%)
Query: 63 FFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTY 122
F L +L +G+V + SS + E V+LSC S S PR+EWK Q + T
Sbjct: 15 FILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAY--SGFSSPRVEWKFDQGDTTRL 72
Query: 123 VFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQV 182
V ++NKI R L T + +VTR D+ Y C +V+ E+ ++L V V
Sbjct: 73 VCYNNKITASYEDRVTFL-PTGITFKSVTREDTGTYTC-MVSEEGGNSYGEVKVKLIVLV 130
Query: 183 KPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHL 242
P P +P + +G A L C E +G P Y+W+++ + +PT+ ++ F NSS+ L
Sbjct: 131 PPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKSTRAFSNSSYVL 190
Query: 243 NSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQ-EMEVYDLNIGGIIGGVLVVLAVL 301
N TG LVF + D+G+Y C A N G+ ME + N+G I+ VLV L +L
Sbjct: 191 NPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIVAAVLVTLILL 250
Query: 302 ALITLGICCAYRRGYFINNKQDGESYKNPGKPDGVNYIRTD--EEGDFRHKSSFVI 355
++ GI AY RG+F K+ S K V Y + EG+F+ SSF++
Sbjct: 251 GILVFGIWFAYSRGHFDRTKKGTSSKK-------VIYSQPSARSEGEFKQTSSFLV 299
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 87.8 bits (216), Expect = 1e-17
Identities = 80/273 (29%), Positives = 116/273 (42%), Gaps = 26/273 (9%)
Query: 58 ARLPDFFLLLLFRG--CLIG-AVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKK 114
A LP FL G CL G AV +K ++ EL+C + S +EW
Sbjct: 2 AELPGPFLCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSF 61
Query: 115 IQ-----DEQTTYVFFDNKI---QGDLAGRAEIL------GKTSLKIWNVTRRDSALYRC 160
+Q E ++F N G + R +L G +LK+ +V D+ Y C
Sbjct: 62 VQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLC 121
Query: 161 EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR 220
+V D +I LTV V P P+C VG L C SEG P+P Y+W R
Sbjct: 122 QVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVR 181
Query: 221 NDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEM 280
PT S S + +G L+ T + SG Y C+A+N GSA C E +
Sbjct: 182 LGT-FPTPS-------PGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASC-ELTL 232
Query: 281 EVYDLNIGGIIGGVLVVLAVLALITLGICCAYR 313
V + + G + G ++ VL + L+++ C R
Sbjct: 233 SVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVR 265
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 80.1 bits (196), Expect = 3e-15
Identities = 78/296 (26%), Positives = 122/296 (41%), Gaps = 29/296 (9%)
Query: 74 IGAVNLKSSNRTPVVQEFESVELSCII-TDSQTSDPRIEWKKIQDEQTTYVF---FDNK- 128
+ A+++++ + +SV L C T + + + I+W K+ T V F NK
Sbjct: 19 VDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKN 78
Query: 129 -IQGDL-AGRAEILGKT-----SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQ 181
I G+L R I S+ I +T D+ Y C V +D + + + L V
Sbjct: 79 YIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL 138
Query: 182 VKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFH 241
V P P C + +G L CQ EG P P YSW R ++ A P
Sbjct: 139 VPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSL 198
Query: 242 LNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCE-EQEMEVYDLNIGGIIGGVLVVLAV 300
N T D SG Y C +SN+ G+ C + +N+ +G + V+A
Sbjct: 199 KNIST----------DTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAA 248
Query: 301 LALITLGICCAYRRGYFIN--NKQDG----ESYKNPGKPDGVNYIRTDEEGDFRHK 350
L +I + I C RG N +K+D E+Y+ P + +EE D+R +
Sbjct: 249 LIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYRQE 304
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 70.1 bits (170), Expect = 3e-12
Identities = 70/262 (26%), Positives = 108/262 (41%), Gaps = 33/262 (12%)
Query: 90 EFESVELSCIITDSQ-------TSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGK 142
E +++++ ++TD++ T R + + +EQ V F + + G
Sbjct: 43 EKDTLDIEWLLTDNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNF---------LAGD 93
Query: 143 TSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMAT 202
SL+I + D Y C+V +N + + VI L V V+P P C + + G T
Sbjct: 94 ASLQIEPLKPSDEGRYTCKV--KNSGRYVWSHVI-LKVLVRPSKPKCELEGELTEGSDLT 150
Query: 203 LHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQY 262
L C+ S G Y W R D R P+ R H G ++ + SG Y
Sbjct: 151 LQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNH----PGRVLLQNLTMSYSGLY 206
Query: 263 YCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQ 322
C A N+AG C + Y +IG + G V ++A LI L + RR +
Sbjct: 207 QCTAGNEAGKESCVVRVTVQYVQSIGMVAGAVTGIVAGALLIFLLVWLLIRR-------K 259
Query: 323 DGESYKNPGKPDGVNYIRTDEE 344
D E Y+ +P N IR D E
Sbjct: 260 DKERYEEEERP---NEIREDAE 278
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 66.6 bits (161), Expect = 3e-11
Identities = 66/266 (24%), Positives = 112/266 (42%), Gaps = 30/266 (11%)
Query: 63 FFLLLLFRGCLIGAVNLKS---SNRTPVVQEFESVELSCIITDSQTSDPR--IEWKKI-- 115
F+ + L CL G V++ + V +V L CI T + S + I+W
Sbjct: 5 FWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK 64
Query: 116 QDEQTTYVFFDNKIQGDLAGR-------AEILGKTSLKIWNVTRRDSALYRCEVVARNDR 168
++ + ++F Q G+ + G S+ I ++ DS +Y C+V D
Sbjct: 65 KEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDF 124
Query: 169 KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR---NDVPL 225
++ ++ ++V VKP P+C V G +L C + G P P Y W++ D+ +
Sbjct: 125 LGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDI-V 183
Query: 226 PTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDL 285
P NP TG LV + + G Y C A N G++ C E ++
Sbjct: 184 PVKENFNP-----------TTGILVIGNLTNFEQGYYQCTAINRLGNSSC-EIDLTSSHP 231
Query: 286 NIGGIIGGVLVVLAVLALITLGICCA 311
+G I+G ++ L A+I +C A
Sbjct: 232 EVGIIVGALIGSLVGAAIIISVVCFA 257
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 63.5 bits (153), Expect = 3e-10
Identities = 57/197 (28%), Positives = 84/197 (42%), Gaps = 19/197 (9%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
S+ I N D+ Y+C V D + V LTV V P P C++ + +G L
Sbjct: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C EG PRP Y W + D L A + GT+ + SG Y
Sbjct: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQ---------DQVQGTVTIRNISALSSGLYQ 214
Query: 264 CIASNDAGSARC--EEQEMEVYDLNIGGIIG----GVLVVLAVLALITLGICCAYRRGYF 317
C+ASN G++ C + Q + NIG I G G ++++ +ALI LG +R
Sbjct: 215 CVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALI-LGAFFYWRSK-- 271
Query: 318 INNKQDGESYKNPGKPD 334
N +++ E N + D
Sbjct: 272 -NKEEEEEEIPNEIRED 287
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 63.5 bits (153), Expect = 3e-10
Identities = 57/197 (28%), Positives = 84/197 (42%), Gaps = 19/197 (9%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
S+ I N D+ Y+C V D + V LTV V P P C++ + +G L
Sbjct: 103 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 162
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C EG PRP Y W + D L A + GT+ + SG Y
Sbjct: 163 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQ---------DQVQGTVTIRNISALSSGLYQ 213
Query: 264 CIASNDAGSARC--EEQEMEVYDLNIGGIIG----GVLVVLAVLALITLGICCAYRRGYF 317
C+ASN G++ C + Q + NIG I G G ++++ +ALI LG +R
Sbjct: 214 CVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALI-LGAFFYWRSK-- 270
Query: 318 INNKQDGESYKNPGKPD 334
N +++ E N + D
Sbjct: 271 -NKEEEEEEIPNEIRED 286
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 60.8 bits (146), Expect = 2e-09
Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 11/129 (8%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLH 204
L+I N T+RD+ Y CE+ R +V L P P VG +L
Sbjct: 6043 LEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE---PPYFVTELEPLEAAVGDSVSLQ 6099
Query: 205 CQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYC 264
CQ + G P SWY+ D L R P +R + + TLVF V+ +DSG+Y C
Sbjct: 6100 CQVA-GTPEITVSWYKGDTKL----RPTPEYRT---YFTNNVATLVFNKVNINDSGEYTC 6151
Query: 265 IASNDAGSA 273
A N G+A
Sbjct: 6152 KAENSIGTA 6160
Score = 56.2 bits (134), Expect = 4e-08
Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 15/129 (11%)
Query: 145 LKIWNVTRRDSALYRC--EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMAT 202
L+I + T D+ Y C E + D +++E VK + PV V VG A+
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPV-----KVSVGDSAS 7979
Query: 203 LHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQY 262
L CQ + G P SWY+ D L + FRN+ TLVF V +DSG+Y
Sbjct: 7980 LQCQLA-GTPEIGVSWYKGDTKLRPTTTYKMHFRNN-------VATLVFNQVDINDSGEY 8031
Query: 263 YCIASNDAG 271
C A N G
Sbjct: 8032 ICKAENSVG 8040
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/187 (30%), Positives = 74/187 (39%), Gaps = 27/187 (14%)
Query: 92 ESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNK-IQGDLAGRAEILGKTS-LKIWN 149
ES + C +T +Q RI W K DNK I+ +G T L+I
Sbjct: 6286 ESADFECHVTGAQPM--RITWSK-----------DNKEIRPGGNYTITCVGNTPHLRILK 6332
Query: 150 VTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKP-VTPVCRVPKAVPVGKMATLHCQES 208
V + DS Y C+ A ND + D +L+V+ P K G+ L C+ S
Sbjct: 6333 VGKGDSGQYTCQ--ATNDVGK-DMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS 6389
Query: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
G P SW+RND L + N F NS L +DSG Y C A N
Sbjct: 6390 -GSPEIKVSWFRNDSELHESWKYNMSFINS-------VALLTINEASAEDSGDYICEAHN 6441
Query: 269 DAGSARC 275
G A C
Sbjct: 6442 GVGDASC 6448
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 14/136 (10%)
Query: 142 KTSLKIWNVTRRDSALYRCEV--VARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGK 199
++SL+++ V DS Y C+V VA + V E V+ + P + K G
Sbjct: 4260 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKK----GD 4315
Query: 200 MATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDS 259
L C+ + G P +W+ ND + S+ F S T L T V +DS
Sbjct: 4316 ATQLACKVT-GTPPIKITWFANDREIKESSKHRMSFVES-------TAVLRLTDVGIEDS 4367
Query: 260 GQYYCIASNDAGSARC 275
G+Y C A N+AGS C
Sbjct: 4368 GEYMCEAQNEAGSDHC 4383
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/198 (26%), Positives = 79/198 (39%), Gaps = 24/198 (12%)
Query: 79 LKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAE 138
+K + V++ +S C IT T R+ W +E T G +
Sbjct: 4864 IKKPSPVLVLRNGQSTTFECQITG--TPKIRVSWYLDGNEITAI---------QKHGISF 4912
Query: 139 ILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVG 198
I G + +I +S Y CE ARND IEL V+ P R K V V
Sbjct: 4913 IDGLATFQISGARVENSGTYVCE--ARNDAGTAS-CSIELKVKEPPT--FIRELKPVEVV 4967
Query: 199 KMATLHCQ-ESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKD 257
K + + + E G P +W +N+ + + + R S F+L+ T
Sbjct: 4968 KYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLH-------ITKCDPS 5020
Query: 258 DSGQYYCIASNDAGSARC 275
D+G+Y CI SN+ GS C
Sbjct: 5021 DTGEYQCIVSNEGGSCSC 5038
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/141 (28%), Positives = 65/141 (46%), Gaps = 20/141 (14%)
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVP--KAV 195
E+ + + I T R+ R EV+ + K + + V++ PVTP V K V
Sbjct: 897 EVKKEVGVSITGTTVREE---RFEVLHGREAKVTETARVPAPVEI-PVTPPTLVSGLKNV 952
Query: 196 PV--GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGT--LVF 251
V G+ TL C S G+P P +WYR D + + + F + ++G L+
Sbjct: 953 TVIEGESVTLECHIS-GYPSPTVTWYREDYQIES---------SIDFQITFQSGIARLMI 1002
Query: 252 TAVHKDDSGQYYCIASNDAGS 272
+DSG++ C A N+AG+
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGT 1023
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/180 (23%), Positives = 66/180 (36%), Gaps = 11/180 (6%)
Query: 96 LSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTR--- 152
LS + +++ + ++E + + T ++ N I+ EI K + + V +
Sbjct: 8255 LSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGM 8314
Query: 153 RDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHP 212
D+ LY C+V ++ + PV P V G+ L C P
Sbjct: 8315 NDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEP 8374
Query: 213 RPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
W + + R SF S T L V K DSG Y C ASN AGS
Sbjct: 8375 I-RIQWLKAGREIKPSDRC-------SFSFASGTAVLELRDVAKADSGDYVCKASNVAGS 8426
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 11/136 (8%)
Query: 141 GKTS-LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGK 199
G TS L +++V + Y C V ND + L + K V G
Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVT--NDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGD 5439
Query: 200 MATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDS 259
+ L C+ + G P W+RN+ LP + F +S + + +DS
Sbjct: 5440 SSRLECKIA-GSPEIRVVWFRNEHELPASDKYRMTFIDS-------VAVIQMNNLSTEDS 5491
Query: 260 GQYYCIASNDAGSARC 275
G + C A N AGS C
Sbjct: 5492 GDFICEAQNPAGSTSC 5507
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 13/121 (10%)
Query: 158 YRCEVVARNDRKEIDEIVIELTVQVKPVT--PVCRVP---KAVPVGKMATLHCQESEGHP 212
Y+ V A N++ + D V+ + V K +T P ++P ++ G+ + G P
Sbjct: 24281 YQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVI-GRP 24339
Query: 213 RPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
RP+ SW ++ PL +R N +S L+ + G +KDD G+Y A+N AG+
Sbjct: 24340 RPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEG-------NKDDFGKYTVTATNSAGT 24392
Query: 273 A 273
A
Sbjct: 24393 A 24393
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 8/81 (9%)
Query: 198 GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKD 257
G+ A LHC+ +G P +W++N+ L + F NS L+ T V +
Sbjct: 3752 GESARLHCK-LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILD-------ITDVKVE 3803
Query: 258 DSGQYYCIASNDAGSARCEEQ 278
DSG Y C A ND GS C +
Sbjct: 3804 DSGSYSCEAVNDVGSDSCSTE 3824
Score = 43.5 bits (101), Expect = 3e-04
Identities = 64/249 (25%), Positives = 90/249 (36%), Gaps = 55/249 (22%)
Query: 43 TLDMALRRPPRLRLCARLPDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITD 102
T+ RR +RL R P+F L L + +G E+V IT
Sbjct: 31672 TMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG----------------ENVRFGVTITV 31715
Query: 103 SQTSDPRIEW----KKIQ--DEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSA 156
+P + W +KI+ D Y F +K G L I +VT D A
Sbjct: 31716 HP--EPHVTWYKSGQKIKPGDNDKKYTFESDK------------GLYQLTINSVTTDDDA 31761
Query: 157 LYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESE------- 209
Y VVARN E D +LTV + P P + + +A CQE +
Sbjct: 31762 EYT--VVARNKYGE-DSCKAKLTVTLHP-PPTDSTLRPMFKRLLANAECQEGQSVCFEIR 31817
Query: 210 --GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
G P P W ++ PL ++ TL +D+G Y A+
Sbjct: 31818 VSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTL------PEDTGYYRVTAT 31871
Query: 268 NDAGSARCE 276
N AGS C+
Sbjct: 31872 NTAGSTSCQ 31880
Score = 42.7 bits (99), Expect = 5e-04
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 15/136 (11%)
Query: 142 KTSLKIWNVTRRDSALYRCEVVAR--NDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGK 199
K L++ N+T +D +Y C+ + D + + I+I+ +K + PV + K
Sbjct: 3605 KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSA-----INK 3659
Query: 200 MATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDS 259
L CQ E + +W ++ LP ++ + TL DS
Sbjct: 3660 KVHLECQVDEDR-KVTVTWSKDGQKLPPG-------KDYKICFEDKIATLEIPLAKLKDS 3711
Query: 260 GQYYCIASNDAGSARC 275
G Y C ASN+AGS+ C
Sbjct: 3712 GTYVCTASNEAGSSSC 3727
Score = 42.4 bits (98), Expect = 6e-04
Identities = 41/187 (21%), Positives = 74/187 (39%), Gaps = 24/187 (12%)
Query: 92 ESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVT 151
ES + C +T +Q ++ W K E + G + + L + V
Sbjct: 8168 ESADFECHVTGTQPI--KVSWAKDSREIRS---------GGKYQISYLENSAHLTVLKVD 8216
Query: 152 RRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTP--VCRVPKAVPVGKMATLHCQESE 209
+ DS Y C V + D +L ++ + + P R+ + V + + +
Sbjct: 8217 KGDSGQYTCYAVNEVGK---DSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRV 8273
Query: 210 GHPRP-HYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
+P +WY+N++ + S F+N++ L + +D+G Y C SN
Sbjct: 8274 AGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGM-------NDAGLYTCKVSN 8326
Query: 269 DAGSARC 275
DAGSA C
Sbjct: 8327 DAGSALC 8333
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 11/128 (8%)
Query: 147 IWNVTRRDSALYRCEVV---ARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
I N+T+ + L+R V R+D + + ++ + ++P +V VG+ +
Sbjct: 23190 ITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKI 23249
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
S G P+P +W ++ +PL +R N S L TL HKDD GQY
Sbjct: 23250 EVPIS-GRPKPTITWTKDGLPLKQTTRINV---TDSLDLT----TLSIKETHKDDGGQYG 23301
Query: 264 CIASNDAG 271
+N G
Sbjct: 23302 ITVANVVG 23309
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLH 204
L++ N++ DS Y CE A N +++VK + P + K A +H
Sbjct: 7363 LEMHNLSVEDSGDYTCE--AHNAAGSASS---STSLKVKEPPIFRKKPHPIETLKGADVH 7417
Query: 205 CQ-ESEGHPRPHYSWYRNDVPLPTDSRANPRFRN--SSFHLNSETGTLVFTAVHKDDSGQ 261
+ E +G P H SWY++ L + + N +S H+ + V D G+
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILN---------VDAADIGE 7468
Query: 262 YYCIASNDAGSARC 275
Y C A+ND GS C
Sbjct: 7469 YQCKATNDVGSDTC 7482
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 10/92 (10%)
Query: 198 GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETG--TLVFTAVH 255
G CQ G+P+PH W ++ VPL T R + N +TG LV +
Sbjct: 1096 GGSVVFGCQVG-GNPKPHVYWKKSGVPLTTGYRYKVSY-------NKQTGECKLVISMTF 1147
Query: 256 KDDSGQYYCIASNDAGSARCEEQEMEVYDLNI 287
DD+G+Y + N G +E D +
Sbjct: 1148 ADDAGEYTIVVRNKHGETSASASLLEEADYEL 1179
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/189 (23%), Positives = 76/189 (40%), Gaps = 29/189 (15%)
Query: 92 ESVELSCIITDSQTSDPRIEWKK----IQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKI 147
E+ L C + T + +EW K + Q F NKI +SL+I
Sbjct: 5719 ETCTLECKVAG--TPELSVEWYKDGKLLTSSQKHKFSFYNKI-------------SSLRI 5763
Query: 148 WNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV-GKMATLHCQ 206
+V R+D+ Y +V N K V++++ + P + R+ V G L C+
Sbjct: 5764 LSVERQDAGTYTFQV-QNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK 5822
Query: 207 ESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIA 266
+ P +W+ + + ++ F ++ TL ++ D G Y C+A
Sbjct: 5823 VAGSSPIS-VAWFHEKTKIVSGAKYQTTFSDN-------VCTLQLNSLDSSDMGNYTCVA 5874
Query: 267 SNDAGSARC 275
+N AGS C
Sbjct: 5875 ANVAGSDEC 5883
Score = 40.0 bits (92), Expect = 0.003
Identities = 50/202 (24%), Positives = 77/202 (38%), Gaps = 37/202 (18%)
Query: 87 VVQEFESVELS----CIITDSQTSDPRI--EW----KKIQDEQTTYVFFDNKIQGDLAGR 136
+V++ ES++++ C + + P + +W K++ + + F NK+ G
Sbjct: 7588 IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG----- 7642
Query: 137 AEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTP-VCRVPKAV 195
LKI NV DS +Y EV + D L V + V P R K
Sbjct: 7643 --------LKIINVAPSDSGVYSFEVQNPVGK---DSCTASLQVSDRTVPPSFTRKLKET 7691
Query: 196 P--VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTA 253
G + C+ G P SW+ + + R L T L
Sbjct: 7692 NGLSGSSVVMECKVY-GSPPISVSWFHEGNEISSG-------RKYQTTLTDNTCALTVNM 7743
Query: 254 VHKDDSGQYYCIASNDAGSARC 275
+ + DSG Y CIA+N AGS C
Sbjct: 7744 LEESDSGDYTCIATNMAGSDEC 7765
Score = 39.3 bits (90), Expect = 0.005
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 22/197 (11%)
Query: 79 LKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAE 138
+K + V ++ ES++L C I+ S + ++ W + E ++ +A
Sbjct: 6367 VKKLEASKVAKQGESIQLECKISGSP--EIKVSWFRNDSELHESWKYNMSFINSVA---- 6420
Query: 139 ILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVG 198
L I + DS Y CE A N + LTV+ PV P G
Sbjct: 6421 -----LLTINEASAEDSGDYICE--AHNGVGDAS-CSTALTVKAPPVFTQKPSPVGALKG 6472
Query: 199 KMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
L C+ S G P W ++ + R + +F+ +S H ++ L A D
Sbjct: 6473 SDVILQCEIS-GTPPFEVVWVKDRKQV----RNSKKFKITSKHFDTSLHILNLEA---SD 6524
Query: 259 SGQYYCIASNDAGSARC 275
G+Y+C A+N+ GS C
Sbjct: 6525 VGEYHCKATNEVGSDTC 6541
Score = 38.9 bits (89), Expect = 0.007
Identities = 44/188 (23%), Positives = 73/188 (38%), Gaps = 30/188 (15%)
Query: 92 ESVELSCIITDSQTSDPRIEW----KKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKI 147
ES L C + S ++ W K++ + T ++F N + L I
Sbjct: 3753 ESARLHCKLKGSPVI--QVTWFKNNKELSESNTVRMYFVNS-------------EAILDI 3797
Query: 148 WNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQE 207
+V DS Y CE V ND D E+ ++ P P + G A L C+
Sbjct: 3798 TDVKVEDSGSYSCEAV--NDVGS-DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEV 3854
Query: 208 SEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
S P SW+++ + R++ ++R S L + + D G+Y C+ +
Sbjct: 3855 SGTGPF-EISWFKDKKQI----RSSKKYRLFS---QKSLVCLEIFSFNSADVGEYECVVA 3906
Query: 268 NDAGSARC 275
N+ G C
Sbjct: 3907 NEVGKCGC 3914
Score = 38.1 bits (87), Expect = 0.012
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Query: 197 VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHK 256
+G+ A L CQ G P P WYR L SR +++ SS + T TL +
Sbjct: 30546 LGEAAQLSCQ-IVGRPLPDIKWYRFGKEL-IQSR---KYKMSS---DGRTHTLTVMTEEQ 30597
Query: 257 DDSGQYYCIASNDAG 271
+D G Y CIA+N+ G
Sbjct: 30598 EDEGVYTCIATNEVG 30612
Score = 38.1 bits (87), Expect = 0.012
Identities = 39/165 (23%), Positives = 61/165 (36%), Gaps = 38/165 (23%)
Query: 141 GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQ----------------VKP 184
G L + ++T+ D YRC+VV ND E D EL V+ +K
Sbjct: 31622 GVAILYVKDITKLDDGTYRCKVV--NDYGE-DSSYAELFVKGVREVYDYYCRRTMKKIKR 31678
Query: 185 VTPVCRVPKAVPVGKMATLHCQESEG-----------HPRPHYSWYRNDVPLPTDSRANP 233
T R+ + P + + G HP PH +WY+ + + P
Sbjct: 31679 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYK------SGQKIKP 31732
Query: 234 RFRNSSFHLNSETG--TLVFTAVHKDDSGQYYCIASNDAGSARCE 276
+ + S+ G L +V DD +Y +A N G C+
Sbjct: 31733 GDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCK 31777
Score = 37.4 bits (85), Expect = 0.021
Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 21/105 (20%)
Query: 192 PKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVF 251
P V GK A C G P+P SWY+ + L T + F + + TL+
Sbjct: 3247 PVTVQSGKPARF-CAVISGRPQPKISWYKEEQLLSTGFKC-------KFLHDGQEYTLLL 3298
Query: 252 TAVHKDDSGQYYCIASNDAGSARCE-------------EQEMEVY 283
+D+ Y C A ND G A +QEM VY
Sbjct: 3299 IEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY 3343
Score = 37.4 bits (85), Expect = 0.021
Identities = 26/82 (31%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 195 VPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAV 254
V G ATL + G P WY++ PL + F+N+ L F +
Sbjct: 4028 VTAGDPATLEYTVA-GTPELKPKWYKDGRPLVASKKYRISFKNN-------VAQLKFYSA 4079
Query: 255 HKDDSGQYYCIASNDAGSARCE 276
DSGQY SN+ GS+ CE
Sbjct: 4080 ELHDSGQYTFEISNEVGSSSCE 4101
Score = 37.0 bits (84), Expect = 0.027
Identities = 37/122 (30%), Positives = 45/122 (36%), Gaps = 11/122 (9%)
Query: 154 DSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPR 213
DS Y C +A N DE LTV+ P P V G T +G P
Sbjct: 7748 DSGDYTC--IATNMAGS-DECSAPLTVREPPSFVQKPDPMDVLTGTNVTF-TSIVKGTPP 7803
Query: 214 PHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
SW++ L R N +S L V SG+Y CI SN+AG A
Sbjct: 7804 FSVSWFKGSSELVPGDRCNVSLEDS-------VAELELFDVDTSQSGEYTCIVSNEAGKA 7856
Query: 274 RC 275
C
Sbjct: 7857 SC 7858
Score = 37.0 bits (84), Expect = 0.027
Identities = 53/201 (26%), Positives = 79/201 (39%), Gaps = 33/201 (16%)
Query: 85 TPV-VQEFESVELSCIITDSQTSDP-RIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGK 142
TPV V E E V+LSC + Q S+P RI+W K E D + G
Sbjct: 8353 TPVTVSEGEYVQLSCHV---QGSEPIRIQWLKAGREIKP---------SDRCSFSFASGT 8400
Query: 143 TSLKIWNVTRRDSALYRCEV--VARNDRKEIDEIVIELTVQVKPVTPVCRV--------- 191
L++ +V + DS Y C+ VA +D + ++ I+ V P T V
Sbjct: 8401 AVLELRDVAKADSGDYVCKASNVAGSDTTK-SKVTIKDKPAVAPATKKAAVDGRLFFVSE 8459
Query: 192 PKAVPVGKMATL-HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLV 250
P+++ V + T + G P P+ W + R + H + L
Sbjct: 8460 PQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKW------RQLNQGGRVFIHQKGDEAKLE 8513
Query: 251 FTAVHKDDSGQYYCIASNDAG 271
K DSG Y C+A N+ G
Sbjct: 8514 IRDTTKTDSGLYRCVAFNEHG 8534
Score = 36.6 bits (83), Expect = 0.035
Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 10/132 (7%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKP-VTPVCRVPKAVPVGKMATL 203
LKI + ++DS Y EV R + L + + P T + ++ G L
Sbjct: 4636 LKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIK-GSFIDL 4694
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C + HP W+++D + + SFH N T L + + DSG Y
Sbjct: 4695 ECIVAGSHPIS-IQWFKDDQEISASEKYK-----FSFHDN--TAFLEISQLEGTDSGTYT 4746
Query: 264 CIASNDAGSARC 275
C A+N AG +C
Sbjct: 4747 CSATNKAGHNQC 4758
Score = 36.6 bits (83), Expect = 0.035
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 11/132 (8%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
+L++ ++ D Y C VA N DE LTVQ P P V GK T
Sbjct: 5856 TLQLNSLDSSDMGNYTC--VAANVAGS-DECRAVLTVQEPPSFVKEPEPLEVLPGKNVTF 5912
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
G P +W+R L R N F ++ L + SG+Y
Sbjct: 5913 -TSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT-------VAELELFNIDISQSGEYT 5964
Query: 264 CIASNDAGSARC 275
C+ SN+AG A C
Sbjct: 5965 CVVSNNAGQASC 5976
Score = 36.2 bits (82), Expect = 0.046
Identities = 19/42 (45%), Positives = 20/42 (47%)
Query: 237 NSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQ 278
N L T TL V K D+GQY C ASN AG C Q
Sbjct: 7257 NYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQ 7298
Score = 35.8 bits (81), Expect = 0.060
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 198 GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKD 257
G T HC+ S G+P P +WY++ + R F L +L V +
Sbjct: 1305 GMGVTFHCKMS-GYPLPKIAWYKDGKRIKHGERYQMDF------LQDGRASLRIPVVLPE 1357
Query: 258 DSGQYYCIASNDAGSARC 275
D G Y ASN G+A C
Sbjct: 1358 DEGIYTAFASNIKGNAIC 1375
Score = 35.8 bits (81), Expect = 0.060
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 176 IELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRF 235
IE+ ++ PV P V +G +A C E + P + W++ + + + R
Sbjct: 3448 IEMEMKAAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIR- 3505
Query: 236 RNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARC 275
SS +++S L D G+Y C ASN+ GS C
Sbjct: 3506 --SSKYISS----LEILRTQVVDCGEYTCKASNEYGSVSC 3539
Score = 35.8 bits (81), Expect = 0.060
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 18/102 (17%)
Query: 183 KPVTPVCRVPKAVPVGKM------------ATLHCQESEGHPRPHYSWYRNDVPLPTDSR 230
+P+TP VP P K ATL C+ + GHP+P WYR + D
Sbjct: 30915 EPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT-GHPKPIVKWYRQGKEIIADGL 30973
Query: 231 ANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
++R F L+ +V DD+ Y A+N GS
Sbjct: 30974 ---KYRIQEF--KGGYHQLIIASVTDDDATVYQVRATNQGGS 31010
Score = 35.4 bits (80), Expect = 0.078
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 7/64 (10%)
Query: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
+G P P SW + + PL TD+R S ++ TL+ K D+G+Y N
Sbjct: 20007 KGKPAPSVSWKKGEDPLATDTRV-------SVESSAVNTTLIVYDCQKSDAGKYTITLKN 20059
Query: 269 DAGS 272
AG+
Sbjct: 20060 VAGT 20063
Score = 35.0 bits (79), Expect = 0.10
Identities = 47/220 (21%), Positives = 73/220 (33%), Gaps = 57/220 (25%)
Query: 92 ESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVT 151
E +L+C++ S + W K + F D G LKI N+T
Sbjct: 32731 EIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD--------GTYELKINNLT 32782
Query: 152 RRDSALYRCEVVAR-------------------------NDRKEIDEIVIELTV----QV 182
D Y CE+ ++ K+ D+ E TV +
Sbjct: 32783 ESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 32842
Query: 183 KPVTPVCRVPKAVPVGKMATLHCQ-------ESEGHPRPHYSWYRNDVPLPTDSRANPRF 235
K P+ P V + T+ ++ G PRP W ++ +
Sbjct: 32843 KAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT--------- 32893
Query: 236 RNSSFHLNSETGTLVFTAVHK---DDSGQYYCIASNDAGS 272
+ + L+ + G F +HK DSG Y C N AGS
Sbjct: 32894 QGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKNSAGS 32932
Score = 34.7 bits (78), Expect = 0.13
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 15/152 (9%)
Query: 126 DNKIQGDLAGRAEILGKTSLKIWN-VTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKP 184
D K++ + + ++N V DS Y C+ A N E+ LTVQ +
Sbjct: 7998 DTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICK--AENSVGEVSASTF-LTVQEQK 8054
Query: 185 VTP-VCRVPKAVP--VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFH 241
+ P R + V VG C S P SWY++ PL F ++
Sbjct: 8055 LPPSFSRQLRDVQETVGLPVVFDCAISGSEPIS-VSWYKDGKPLKDSPNVQTSFLDN--- 8110
Query: 242 LNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
T TL + +GQY C A+N GSA
Sbjct: 8111 ----TATLNIFKTDRSLAGQYSCTATNPIGSA 8138
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 8/95 (8%)
Query: 184 PVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLN 243
P + P VG+ A C + P SW ++ + + + + +S HL
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIK-VSWAKDSREIRSGGKYQISYLENSAHLT 8211
Query: 244 SETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQ 278
V K DSGQY C A N+ G C Q
Sbjct: 8212 -------VLKVDKGDSGQYTCYAVNEVGKDSCTAQ 8239
Score = 34.3 bits (77), Expect = 0.17
Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 11/67 (16%)
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAV--HKDDSGQYYCIAS 267
G P+P SW++++ + D R H+ + TL + + DSG+Y +
Sbjct: 16844 GKPKPKVSWFKDEADVLEDDRT---------HIKTTPATLALEKIKAKRSDSGKYCVVVE 16894
Query: 268 NDAGSAR 274
N GS +
Sbjct: 16895 NSTGSRK 16901
Score = 33.9 bits (76), Expect = 0.23
Identities = 38/185 (20%), Positives = 74/185 (40%), Gaps = 29/185 (15%)
Query: 96 LSCIITDSQTSDPRIEW----KKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVT 151
L C++T T + +W +++ + ++ F NK+ SLKI
Sbjct: 6664 LECVVTG--TPELSAKWFKDGRELSADSKHHITFINKV-------------ASLKIPCAE 6708
Query: 152 RRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV-GKMATLHCQESEG 210
D LY EV + K + + ++ ++ P + + ++ + G L C+ S
Sbjct: 6709 MSDKGLYSFEV-KNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS 6767
Query: 211 HPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDA 270
P W+++ + + + F + LN + + D+G Y C+A+N A
Sbjct: 6768 APIS-VGWFQDGNEIVSGPKCQSSFSENVCTLN-------LSLLEPSDTGIYTCVAANVA 6819
Query: 271 GSARC 275
GS C
Sbjct: 6820 GSDEC 6824
Score = 33.9 bits (76), Expect = 0.23
Identities = 36/123 (29%), Positives = 46/123 (37%), Gaps = 13/123 (10%)
Query: 154 DSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV-GKMATLHCQESEGHP 212
D+ +Y C VA N DE LTVQ P + P +V V M+ G P
Sbjct: 6807 DTGIYTC--VAANVAGS-DECSAVLTVQEPPSFE--QTPDSVEVLPGMSLTFTSVIRGTP 6861
Query: 213 RPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
W++ L N L L V +SG Y C+ +NDAGS
Sbjct: 6862 PFKVKWFKGSRELVPGESCN-------ISLEDFVTELELFEVQPLESGDYSCLVTNDAGS 6914
Query: 273 ARC 275
A C
Sbjct: 6915 ASC 6917
Score = 33.1 bits (74), Expect = 0.39
Identities = 41/148 (27%), Positives = 62/148 (41%), Gaps = 20/148 (13%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKM--A 201
+L+I +V S Y C+ A+N+ ++ L VQ + K+V V +
Sbjct: 5104 TLQIRSVDNGHSGRYTCQ--AKNE-SGVERCYAFLLVQEP--AQIVEKAKSVDVTEKDPM 5158
Query: 202 TLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNS--SFHLNSETGTLVFTAVHKDDS 259
TL C + G P W ++ + + F N+ SF + S V K DS
Sbjct: 5159 TLECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQS---------VMKQDS 5208
Query: 260 GQYYCIASNDAGSARCEEQEMEVYDLNI 287
GQY ND GS+ C+ + V D NI
Sbjct: 5209 GQYTFKVENDFGSSSCDAY-LRVLDQNI 5235
Score = 33.1 bits (74), Expect = 0.39
Identities = 29/98 (29%), Positives = 37/98 (37%), Gaps = 25/98 (25%)
Query: 176 IELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRF 235
IE TV + PVT CR+ + P+ WYR+ V L D F
Sbjct: 6184 IEQTVGL-PVTLTCRLNGSAPI-----------------QVCWYRDGVLLRDDENLQTSF 6225
Query: 236 RNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
++ TL SGQY C ASN G+A
Sbjct: 6226 VDN-------VATLKILQTDLSHSGQYSCSASNPLGTA 6256
Score = 33.1 bits (74), Expect = 0.39
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 10/133 (7%)
Query: 143 TSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMAT 202
TS+ I NV D Y+C+ A ND D V + ++ P + VGK
Sbjct: 7454 TSIHILNVDAADIGEYQCK--ATNDVGS-DTCVGSIALKAPPRFVKKLSDISTVVGKEVQ 7510
Query: 203 LHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQY 262
L EG W+++ + +S N + TL F+ V ++G+Y
Sbjct: 7511 LQTT-IEGAEPISVVWFKDKGEIVRESD------NIWISYSENIATLQFSRVEPANAGKY 7563
Query: 263 YCIASNDAGSARC 275
C NDAG C
Sbjct: 7564 TCQIKNDAGMQEC 7576
Score = 32.7 bits (73), Expect = 0.51
Identities = 29/132 (21%), Positives = 52/132 (39%), Gaps = 11/132 (8%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
SL++ N+ D+A Y C+V D+ + +P + + + + +
Sbjct: 5293 SLEVNNLELEDTANYTCKV----SNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVE 5348
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
+G P W+++DV L + + S+ LN +V +GQY
Sbjct: 5349 FKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLN-------LYSVDASKTGQYT 5401
Query: 264 CIASNDAGSARC 275
C +ND GS C
Sbjct: 5402 CHVTNDVGSDSC 5413
Score = 32.7 bits (73), Expect = 0.51
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
+ P WY N V L S+ + + N+S L TL H DDSG Y + +N
Sbjct: 32398 QSKPTAEVKWYHNGVELQESSKIH--YTNTSGVL-----TLEILDCHTDDSGTYRAVCTN 32450
Query: 269 DAGSA 273
G A
Sbjct: 32451 YKGEA 32455
Score = 32.3 bits (72), Expect = 0.66
Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 13/125 (10%)
Query: 154 DSALYRCEVVARNDRKEID-----EIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQES 208
++ +Y V +N+ E D E+V++ +Q KPV + ++ + V T+ +
Sbjct: 18167 ENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQ-KPVLDL-KLSGVLTVKAGDTIRLEAG 18224
Query: 209 -EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
G P P +W ++ TD +PR + + +++ T + D G+Y A+
Sbjct: 18225 VRGKPFPEVAWTKDKDA--TDLTRSPRVKIDT---RADSSKFSLTKAKRSDGGKYVVTAT 18279
Query: 268 NDAGS 272
N AGS
Sbjct: 18280 NTAGS 18284
Score = 32.0 bits (71), Expect = 0.87
Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 22/161 (13%)
Query: 121 TYVFFDNKIQGDLAGRAEILGKTS-LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIE-- 177
T+ D +I+ R + T+ L++ +V DS Y CE IVI
Sbjct: 4332 TWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKE 4391
Query: 178 ---LTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPR 234
T + KP+ V K V +A E G P +W++++ L + +
Sbjct: 4392 SPYFTKEFKPI----EVLKEYDVMLLA-----EVAGTPPFEITWFKDNTILRSGRKYKTF 4442
Query: 235 FRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARC 275
++ L L F A D+G+Y C +N+ GS+ C
Sbjct: 4443 IQDHLVSLQ----ILKFVAA---DAGEYQCRVTNEVGSSIC 4476
Score = 32.0 bits (71), Expect = 0.87
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 254 VHKDDSGQYYCIASNDAGSARCEEQ 278
V K DSGQY C A+ND G C Q
Sbjct: 6333 VGKGDSGQYTCQATNDVGKDMCSAQ 6357
Score = 32.0 bits (71), Expect = 0.87
Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASND 269
G P P +W++++VPL +R N ++ L ++D G Y +N
Sbjct: 22173 GRPTPAVTWHKDNVPLKQTTRVNAESTENN-------SLLTIKDACREDVGHYVVKLTNS 22225
Query: 270 AGSA 273
AG A
Sbjct: 22226 AGEA 22229
Score = 31.6 bits (70), Expect = 1.1
Identities = 44/185 (23%), Positives = 70/185 (37%), Gaps = 25/185 (13%)
Query: 92 ESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVT 151
E L C + T + RI W K + + + + + ++A SL I V
Sbjct: 7035 EPATLQCKVDG--TPEIRISWYKEHTKLRSAPAYKMQFKNNVA---------SLVINKVD 7083
Query: 152 RRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPV-CRVPKAV--PVGKMATLHCQES 208
D Y C+ A N + + L ++ + + P R K V +G C+ +
Sbjct: 7084 HSDVGEYSCK--ADNSVGAVASSAV-LVIKARKLPPFFARKLKDVHETLGFPVAFECRIN 7140
Query: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
P SWY++ V L D+ F ++ TL + GQY C ASN
Sbjct: 7141 GSEPL-QVSWYKDGVLLKDDANLQTSFVHN-------VATLQILQTDQSHIGQYNCSASN 7192
Query: 269 DAGSA 273
G+A
Sbjct: 7193 PLGTA 7197
Score = 31.2 bits (69), Expect = 1.5
Identities = 23/112 (20%), Positives = 41/112 (36%), Gaps = 10/112 (8%)
Query: 167 DRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--GKMATLHCQESEGHPRPHYSWYRNDVP 224
+ K ++E ++ + P+++ V G+ A C +++G P P +W R
Sbjct: 32542 EEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSC-DTDGEPVPTVTWLRKGQV 32600
Query: 225 LPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCE 276
L T +R T ++V D G Y + N G E
Sbjct: 32601 LSTSAR-------HQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAE 32645
Score = 30.8 bits (68), Expect = 1.9
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 30/175 (17%)
Query: 108 PRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARND 167
P+I W K +EQ F K D G+ + +L + D+A+Y CE A+ND
Sbjct: 3268 PKISWYK--EEQLLSTGFKCKFLHD--GQ-----EYTLLLIEAFPEDAAVYTCE--AKND 3316
Query: 168 RKEIDEIVIELTVQV-KPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHY---------- 216
+ L+V+V + V+P +P P SEG P
Sbjct: 3317 YG-VATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKV 3375
Query: 217 SWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAG 271
SWY D + + + FR + F +T L + +D G Y +ASN G
Sbjct: 3376 SWYSKDKKI----KPSRFFRMTQFE---DTYQLEIAEAYPEDEGTYTFVASNAVG 3423
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASND 269
G P WY+++ + S+ F +S L + +DSG Y C A N
Sbjct: 7331 GSPEIKVLWYKDETEIQESSKFRMSFVDS-------VAVLEMHNLSVEDSGDYTCEAHNA 7383
Query: 270 AGSA 273
AGSA
Sbjct: 7384 AGSA 7387
Score = 30.4 bits (67), Expect = 2.5
Identities = 15/59 (25%), Positives = 24/59 (40%), Gaps = 7/59 (11%)
Query: 217 SWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARC 275
+W ++ + D F N+ +L + + G+Y C A NDAG RC
Sbjct: 4518 TWLKDSDEITEDDNIRMTFENN-------VASLYLSGIEVKHDGKYVCQAKNDAGIQRC 4569
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 7/69 (10%)
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASND 269
G P +W +N + + R N S L + T+ +D+GQY C N
Sbjct: 7893 GTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTV-------EDAGQYNCYIENA 7945
Query: 270 AGSARCEEQ 278
+G C Q
Sbjct: 7946 SGKDSCSAQ 7954
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
Query: 209 EGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASN 268
+G P P +W +++ L +D+R + +SS L V ++D+G+Y N
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIENTDSS-------SLLTIPQVTRNDTGKYILTIEN 27348
Query: 269 DAGSARCEEQEMEVYD 284
G + ++V D
Sbjct: 27349 GVGEPKSSTVSVKVLD 27364
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/65 (27%), Positives = 26/65 (40%), Gaps = 7/65 (10%)
Query: 207 ESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIA 266
E G P P W++N++P+ S N S + +L DSG+Y A
Sbjct: 33156 EISGEPSPEIEWFKNNLPISISS-------NVSISRSRNVYSLEIRNASVSDSGKYTIKA 33208
Query: 267 SNDAG 271
N G
Sbjct: 33209 KNFRG 33213
Score = 30.0 bits (66), Expect = 3.3
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 198 GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKD 257
G AT S G P P SW+R+ + T + + S L AV K
Sbjct: 20 GSTATFEAHIS-GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK-----LTIPAVTKA 73
Query: 258 DSGQYYCIASNDAGSA 273
+SG+Y A+N +G A
Sbjct: 74 NSGRYSLKATNGSGQA 89
Score = 29.6 bits (65), Expect = 4.3
Identities = 30/130 (23%), Positives = 52/130 (40%), Gaps = 15/130 (11%)
Query: 154 DSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPR 213
D +Y EV + K+ + +++K ++P+ + V G+ AT C+ S H +
Sbjct: 11550 DEGVYTAEV----EGKKTSARLFVTGIRLKFMSPL--EDQTVKEGETATFVCELS--HEK 11601
Query: 214 PHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
H W++ND L T R +T L V DD Q + +A
Sbjct: 11602 MHVVWFKNDAKLHTS-------RTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTA 11654
Query: 274 RCEEQEMEVY 283
+ + E + Y
Sbjct: 11655 QLKVLEADPY 11664
Score = 29.6 bits (65), Expect = 4.3
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 16/127 (12%)
Query: 154 DSALYRCEVVAR-----NDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQES 208
+ A Y+ +AR + E + V L V P + K++ K T C ++
Sbjct: 19258 EKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA 19317
Query: 209 E--GHPRPHYSWYRNDVPL-PTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCI 265
G P P SW ++ L P + RN TL +V++ DSG Y
Sbjct: 19318 TVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC--------TLELFSVNRKDSGDYTIT 19369
Query: 266 ASNDAGS 272
A N +GS
Sbjct: 19370 AENSSGS 19376
Score = 29.6 bits (65), Expect = 4.3
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 7/63 (11%)
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASND 269
G P P W R D + +R +N+ F L+ + D GQY ASN
Sbjct: 23651 GKPLPTIEWLRGDKEIEESARCE--IKNTDFK-----ALLIVKDAIRIDGGQYILRASNV 23703
Query: 270 AGS 272
AGS
Sbjct: 23704 AGS 23706
Score = 29.3 bits (64), Expect = 5.6
Identities = 29/129 (22%), Positives = 46/129 (35%), Gaps = 13/129 (10%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-PVTPVCRVPKAVPVGKMATL 203
L+I++ D Y C V E+ + T +K P T V +V + +G
Sbjct: 3888 LEIFSFNSADVGEYECVVA-----NEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVT 3942
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
G +W + + D + F N L+ V G+Y
Sbjct: 3943 LQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNG-------VAVLIIPDVQISFGGKYT 3995
Query: 264 CIASNDAGS 272
C+A N+AGS
Sbjct: 3996 CLAENEAGS 4004
Score = 29.3 bits (64), Expect = 5.6
Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 13/135 (9%)
Query: 143 TSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPK-AVPVGKMA 201
T L+++ V +S Y C V ND L V+ +P T V R+ +V G
Sbjct: 6889 TELELFEVQPLESGDYSCLVT--NDAGSAS-CTTHLFVK-EPATFVKRLADFSVETGSPI 6944
Query: 202 TLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQ 261
L + G P SW +++ + R + S L T+ +D Q
Sbjct: 6945 VLEATYT-GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTI-------EDYAQ 6996
Query: 262 YYCIASNDAGSARCE 276
Y C+ N+AG CE
Sbjct: 6997 YSCLIENEAGQDICE 7011
Score = 29.3 bits (64), Expect = 5.6
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 21/126 (16%)
Query: 153 RDSALYRCEVVARNDRKEIDEIVI-ELTVQVKPVTP---VCRVPKA---VPVGKMATLHC 205
++ ++ V A+N++ D + I +TV+ +TP + +P A V +G L
Sbjct: 27526 KEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLEL 27585
Query: 206 QESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETG---TLVFTAVHKDDSGQY 262
+G P+P SW ++ +PL + S F S+T TL K+ G+Y
Sbjct: 27586 PY-KGKPKPSISWLKDGLPL----------KESEFVRFSKTENKITLSIKNAKKEHGGKY 27634
Query: 263 YCIASN 268
I N
Sbjct: 27635 TVILDN 27640
Score = 28.9 bits (63), Expect = 7.3
Identities = 45/195 (23%), Positives = 71/195 (36%), Gaps = 29/195 (14%)
Query: 82 SNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILG 141
S+ P+V+ ++ E+S S T + W K +K Q + + +I
Sbjct: 5520 SSFPPIVETLKNAEVSLECELSGTPPFEVVWYK------------DKRQLRSSKKYKIAS 5567
Query: 142 K---TSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-PVTPVCRVPK-AVP 196
K TS+ I NV D Y C+ + E+ TV++K P V ++ V
Sbjct: 5568 KNFHTSIHILNVDTSDIGEYHCKA-----QNEVGSDTCVCTVKLKEPPRFVSKLNSLTVV 5622
Query: 197 VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHK 256
G+ A L EG W + + +S N TL F
Sbjct: 5623 AGEPAELQAS-IEGAQPIFVQWLKEKEEVIRESE------NIRITFVENVATLQFAKAEP 5675
Query: 257 DDSGQYYCIASNDAG 271
++G+Y C ND G
Sbjct: 5676 ANAGKYICQIKNDGG 5690
Score = 28.9 bits (63), Expect = 7.3
Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 6/79 (7%)
Query: 194 AVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTA 253
++ GK+ T+ C + G P P +W + + + N+ + TL+
Sbjct: 33339 SIDEGKVLTVACAFT-GEPTPEVTWSCGGRKIHSQEQGRFHIENTD-----DLTTLIIMD 33392
Query: 254 VHKDDSGQYYCIASNDAGS 272
V K D G Y N+ GS
Sbjct: 33393 VQKQDGGLYTLSLGNEFGS 33411
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 59.3 bits (142), Expect = 5e-09
Identities = 51/195 (26%), Positives = 77/195 (39%), Gaps = 28/195 (14%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKI 147
+ E ++ L+CI T +P + W+ I + +V D L+I
Sbjct: 147 INEGNNISLTCIATGRP--EPTVTWRHISPKAVGFVSEDEY----------------LEI 188
Query: 148 WNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQE 207
+TR S Y C A ND +++TV P + VPVG+ TL C E
Sbjct: 189 QGITREQSGDYECS--ASNDVAAPVVRRVKVTVNYPPYISEAK-GTGVPVGQKGTLQC-E 244
Query: 208 SEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
+ P + WY++D L + + + N F L+F V + D G Y C+AS
Sbjct: 245 ASAVPSAEFQWYKDDKRL-IEGKKGVKVENRPF-----LSKLIFFNVSEHDYGNYTCVAS 298
Query: 268 NDAGSARCEEQEMEV 282
N G EV
Sbjct: 299 NKLGHTNASIMLFEV 313
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 58.9 bits (141), Expect = 7e-09
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 18/168 (10%)
Query: 110 IEWKKIQDEQTTYVFFDNKIQGDLA--GRAEILGKTSLKIWNVTRRDSALYRCEVVARND 167
+EW D V K G L G+ +L +L+I + D Y C+ V+
Sbjct: 436 VEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG 495
Query: 168 RKEIDEIVIELTVQVKPVTPVCRVPK--AVPVGKMATLHCQESEGHPRPHYSWYRNDVPL 225
K++ ++LTV+ K + ++P+ +V VGK + C ++G P+P +W + V +
Sbjct: 496 VKKVS---VQLTVKPKALAVFTQLPQDTSVEVGKNINISCH-AQGEPQPIITWNKEGVQI 551
Query: 226 PTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
+ FH++ E GTL D G+Y C+A N G A
Sbjct: 552 TESGK---------FHVDDE-GTLTIYDAGFPDQGRYECVARNSFGLA 589
Score = 42.7 bits (99), Expect = 5e-04
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 13/84 (15%)
Query: 195 VPVGKMATLHCQESEGHPRPHYSWYRND--VPLPTDSRANPRFRNSSFHLNSETGTLVFT 252
VP G C+ +EG+P+P W N+ + L D+R N + GTL+
Sbjct: 245 VPSGNTVYFTCR-AEGNPKPEIIWIHNNHSLDLEDDTRLNV----------FDDGTLMIR 293
Query: 253 AVHKDDSGQYYCIASNDAGSARCE 276
+ D G Y C+A N AG A+ +
Sbjct: 294 NTRESDQGVYQCMARNSAGEAKTQ 317
Score = 41.2 bits (95), Expect = 0.001
Identities = 43/186 (23%), Positives = 67/186 (36%), Gaps = 29/186 (15%)
Query: 93 SVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTR 152
S L C+ T P I W + DN ++ D G + + L + N+T+
Sbjct: 346 STTLECMATGHP--HPLITWTR-----------DNGLELD--GSRHVATSSGLYLQNITQ 390
Query: 153 RDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHP 212
RD + C N+ + + VQ P V + V C E++G+P
Sbjct: 391 RDHGRFTCHA---NNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLC-EADGNP 446
Query: 213 RPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
P W + LP + + H +GTL + D GQY C A + G
Sbjct: 447 PPVIVWTKTGGQLPVEGQ----------HTVLSSGTLRIDRAAQHDQGQYECQAVSSLGV 496
Query: 273 ARCEEQ 278
+ Q
Sbjct: 497 KKVSVQ 502
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 58.5 bits (140), Expect = 9e-09
Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 28/184 (15%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKI 147
+ E ++ L+CI T +P + W+ I + +V D L+I
Sbjct: 147 INEGNNISLTCIATGRP--EPTVTWRHISPKAVGFVSEDEY----------------LEI 188
Query: 148 WNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQE 207
+TR S Y C A ND +++TV P + VPVG+ TL C E
Sbjct: 189 QGITREQSGDYECS--ASNDVAAPVVRRVKVTVNYPPYISEAK-GTGVPVGQKGTLQC-E 244
Query: 208 SEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
+ P + WY++D L + + + N F L+F V + D G Y C+AS
Sbjct: 245 ASAVPSAEFQWYKDDKRL-IEGKKGVKVENRPF-----LSKLIFFNVSEHDYGNYTCVAS 298
Query: 268 NDAG 271
N G
Sbjct: 299 NKLG 302
Score = 39.7 bits (91), Expect = 0.004
Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 30/189 (15%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKT---- 143
V++ ES L C I + T R+ W ++T ++ N + L R +L T
Sbjct: 47 VRQGESATLRCTIDNRVT---RVAWLN----RSTILYAGND-KWCLDPRVVLLSNTQTQY 98
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
S++I NV D Y C V N K + L VQV P ++ G +L
Sbjct: 99 SIEIQNVDVYDEGPYTCSVQTDNHPKTSR---VHLIVQVSPKIVEISSDISINEGNNISL 155
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C + G P P +W +P+ + SE L + ++ SG Y
Sbjct: 156 TCIAT-GRPEPTVTW----------RHISPK----AVGFVSEDEYLEIQGITREQSGDYE 200
Query: 264 CIASNDAGS 272
C ASND +
Sbjct: 201 CSASNDVAA 209
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 58.5 bits (140), Expect = 9e-09
Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 28/184 (15%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKI 147
+ E ++ L+CI T +P + W+ I + +V D L+I
Sbjct: 147 INEGNNISLTCIATGRP--EPTVTWRHISPKAVGFVSEDEY----------------LEI 188
Query: 148 WNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQE 207
+TR S Y C A ND +++TV P + VPVG+ TL C E
Sbjct: 189 QGITREQSGDYECS--ASNDVAAPVVRRVKVTVNYPPYISEAK-GTGVPVGQKGTLQC-E 244
Query: 208 SEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
+ P + WY++D L + + + N F L+F V + D G Y C+AS
Sbjct: 245 ASAVPSAEFQWYKDDKRL-IEGKKGVKVENRPF-----LSKLIFFNVSEHDYGNYTCVAS 298
Query: 268 NDAG 271
N G
Sbjct: 299 NKLG 302
Score = 41.6 bits (96), Expect = 0.001
Identities = 54/212 (25%), Positives = 82/212 (38%), Gaps = 37/212 (17%)
Query: 72 CLIGAVNLKSSNRT-------PVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVF 124
CL V ++S + T V++ ES L C I + T R+ W ++T ++
Sbjct: 24 CLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVT---RVAWLN----RSTILY 76
Query: 125 FDNKIQGDLAGRAEILGKT----SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTV 180
N + L R +L T S++I NV D Y C V N K + L V
Sbjct: 77 AGND-KWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSR---VHLIV 132
Query: 181 QVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSF 240
QV P ++ G +L C + G P P +W +P+ +
Sbjct: 133 QVSPKIVEISSDISINEGNNISLTCIAT-GRPEPTVTW----------RHISPK----AV 177
Query: 241 HLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
SE L + ++ SG Y C ASND +
Sbjct: 178 GFVSEDEYLEIQGITREQSGDYECSASNDVAA 209
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 58.5 bits (140), Expect = 9e-09
Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 28/184 (15%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKI 147
+ E ++ L+CI T +P + W+ I + +V D L+I
Sbjct: 147 INEGNNISLTCIATGRP--EPTVTWRHISPKAVGFVSEDEY----------------LEI 188
Query: 148 WNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQE 207
+TR S Y C A ND +++TV P + VPVG+ TL C E
Sbjct: 189 QGITREQSGDYECS--ASNDVAAPVVRRVKVTVNYPPYISEAK-GTGVPVGQKGTLQC-E 244
Query: 208 SEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIAS 267
+ P + WY++D L + + + N F L+F V + D G Y C+AS
Sbjct: 245 ASAVPSAEFQWYKDDKRL-IEGKKGVKVENRPF-----LSKLIFFNVSEHDYGNYTCVAS 298
Query: 268 NDAG 271
N G
Sbjct: 299 NKLG 302
Score = 39.7 bits (91), Expect = 0.004
Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 30/189 (15%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKT---- 143
V++ ES L C I + T R+ W ++T ++ N + L R +L T
Sbjct: 47 VRQGESATLRCTIDNRVT---RVAWLN----RSTILYAGND-KWCLDPRVVLLSNTQTQY 98
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
S++I NV D Y C V N K + L VQV P ++ G +L
Sbjct: 99 SIEIQNVDVYDEGPYTCSVQTDNHPKTSR---VHLIVQVSPKIVEISSDISINEGNNISL 155
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C + G P P +W +P+ + SE L + ++ SG Y
Sbjct: 156 TCIAT-GRPEPTVTW----------RHISPK----AVGFVSEDEYLEIQGITREQSGDYE 200
Query: 264 CIASNDAGS 272
C ASND +
Sbjct: 201 CSASNDVAA 209
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 58.5 bits (140), Expect = 9e-09
Identities = 73/308 (23%), Positives = 115/308 (37%), Gaps = 41/308 (13%)
Query: 65 LLLLFRGCLIGAVNLKSSNRTPV-VQEFESVELSC-IITDSQTSDPR---IEWKKIQDEQ 119
LL+ L+ AV + + + + E ++V L C + D + P IEW ++ +
Sbjct: 10 LLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDP 69
Query: 120 TTY---VFF---DNKIQGD----LAGRAEILGK------TSLKIWNVTRRDSALYRCEVV 163
+ VF D +I L R S+ + N+ D+A Y C V
Sbjct: 70 AHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRV- 128
Query: 164 ARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR--- 220
+ ++++ TVQ +P P+C + G L C S G Y W +
Sbjct: 129 -KKTTMATRKVIV--TVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISG 185
Query: 221 NDVPLPTDSRANPRFRNS------SFHLNSE----TGTLVFTAVHKDDSGQYYCIASNDA 270
+ P S + +S SFH + G LV + + D G Y C +N+
Sbjct: 186 HHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNV 245
Query: 271 GSARCEEQEMEVYDLNIGGIIG---GVLVVLAVLALITLGICCAYRRGYFINNKQDGESY 327
G + C + IG IIG G L+ L LA+ G+ C G + Y
Sbjct: 246 GYSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAFGY 305
Query: 328 KNPGKPDG 335
N G G
Sbjct: 306 GNGGGVGG 313
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 58.2 bits (139), Expect = 1e-08
Identities = 57/190 (30%), Positives = 76/190 (40%), Gaps = 32/190 (16%)
Query: 89 QEF---ESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSL 145
QEF E E+ C ++ S P + W +E TT DN R +L +L
Sbjct: 124 QEFKQGEDAEVVCRVSSSPA--PAVSWLYHNEEVTT--ISDN--------RFAMLANNNL 171
Query: 146 KIWNVTRRDSALYRCE--VVARNDRKEIDEIVIELTVQVKPV--TPVCRVPKAVPVGKMA 201
+I N+ + D +YRCE V AR EID I + V V P P G+
Sbjct: 172 QILNINKSDEGIYRCEGRVEARG---EIDFRDIIVIVNVPPAISMPQKSFNATAERGEEM 228
Query: 202 TLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQ 261
T C+ S G P P SW+RN + N + L L + D G
Sbjct: 229 TFSCRAS-GSPEPAISWFRNGKLIE---------ENEKYILKGSNTELTVRNIINSDGGP 278
Query: 262 YYCIASNDAG 271
Y C A+N AG
Sbjct: 279 YVCRATNKAG 288
Score = 35.4 bits (80), Expect = 0.078
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 15/125 (12%)
Query: 142 KTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMA 201
++ L I+N D+ +YRC+ A + + + E + L + K P+ G+ A
Sbjct: 75 RSRLTIYNANIEDAGIYRCQ--ATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDA 132
Query: 202 TLHCQESEGHPRPHYSW--YRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDS 259
+ C+ S P P SW + +V +D+R N+ LN ++K D
Sbjct: 133 EVVCRVSSS-PAPAVSWLYHNEEVTTISDNRFAMLANNNLQILN----------INKSDE 181
Query: 260 GQYYC 264
G Y C
Sbjct: 182 GIYRC 186
>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
Length = 390
Score = 57.8 bits (138), Expect = 1e-08
Identities = 51/179 (28%), Positives = 75/179 (41%), Gaps = 20/179 (11%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEI---DEIVIELTVQVKPVTPVCRVPKAVPVGKM 200
SL++ + +DS Y C V ++ + + +EL V V P P CR+ VG
Sbjct: 110 SLRLEGLQEKDSGPYSCSVNVQDKQGKSRGHSIKTLELNVLVPPAPPSCRLQGVPHVGAN 169
Query: 201 ATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRN-SSFHLNSETGTLVFTAVHKDDS 259
TL CQ P Y W R P F+ + L+ G+L T + +
Sbjct: 170 VTLSCQSPRSKPAVQYQW----------DRQLPSFQTFFAPALDVIRGSLSLTNLSSSMA 219
Query: 260 GQYYCIASNDAGSARCE---EQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRG 315
G Y C A N+ G+A+C E + G + G LV L +LA + L +RRG
Sbjct: 220 GVYVCKAHNEVGTAQCNVTLEVSTGPGAAVVAGAVVGTLVGLGLLAGLVL---LYHRRG 275
>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
Length = 416
Score = 57.8 bits (138), Expect = 1e-08
Identities = 62/258 (24%), Positives = 102/258 (39%), Gaps = 18/258 (6%)
Query: 59 RLPDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDE 118
RL F LLL + + VN+ S R +S LS + + + P ++W+ +D+
Sbjct: 16 RLAPFVYLLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDRPVVKWQLKRDK 75
Query: 119 QTTYVF-----FDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDE 173
T V ++ D R + SL + ++ D Y E+ +D E
Sbjct: 76 PVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFT-GE 134
Query: 174 IVIELTVQVKPVTPVCRVPKA--VPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRA 231
I LTV V P V + + + TL+C G +P Y+W ++ PL DSR
Sbjct: 135 KTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENG-TKPSYTWLKDGKPLLNDSR- 192
Query: 232 NPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGII 291
L+ + L T V +D Y C+ N R ++ VY + II
Sbjct: 193 --------MLLSPDQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRSSLYII 244
Query: 292 GGVLVVLAVLALITLGIC 309
+ ++ L+T+ C
Sbjct: 245 LSTGGIFLLVTLVTVCAC 262
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform
5 precursor [Homo sapiens]
Length = 1502
Score = 57.4 bits (137), Expect = 2e-08
Identities = 62/215 (28%), Positives = 95/215 (44%), Gaps = 30/215 (13%)
Query: 84 RTPVVQEFESVELSCIITDSQTSDPR--IEW----KKIQDEQTTYVFFDNKIQGDLAGRA 137
RTPV Q S ++ I + T DPR I W KK+ +++ + FD+ G
Sbjct: 28 RTPVDQTGVSGGVASFICQA-TGDPRPKIVWNKKGKKVSNQRFEVIEFDD-------GSG 79
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-------PVTPVCR 190
+L L+ T RD A+Y C VA N+ EI + LTV + P +
Sbjct: 80 SVLRIQPLR----TPRDEAIYEC--VASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGP 132
Query: 191 VPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLV 250
K V + AT+ C S G+P P +W+++ +P+ T S N R + G L
Sbjct: 133 QLKVVERTRTATMLCAAS-GNPDPEITWFKDFLPVDT-SNNNGRIKQLRSGGTPIRGALQ 190
Query: 251 FTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDL 285
+ D G+Y C+A+N AG+ + V +L
Sbjct: 191 IEQSEESDQGKYECVATNSAGTRYSAPANLYVREL 225
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 57.4 bits (137), Expect = 2e-08
Identities = 61/217 (28%), Positives = 96/217 (44%), Gaps = 31/217 (14%)
Query: 84 RTPVVQEFESVELSCIITDSQTSDPR--IEW----KKIQDEQTTYVFFDNKIQGDLAGRA 137
RTPV Q S ++ I + T DPR I W KK+ +++ + FD+ G
Sbjct: 28 RTPVDQTGVSGGVASFICQA-TGDPRPKIVWNKKGKKVSNQRFEVIEFDD-------GSG 79
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-------PVTPVCR 190
+L L+ T RD A+Y C VA N+ EI + LTV + P +
Sbjct: 80 SVLRIQPLR----TPRDEAIYEC--VASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGP 132
Query: 191 VPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRAN--PRFRNSSFHLNSETGT 248
K V + AT+ C S G+P P +W+++ +P+ T + + R+ S G
Sbjct: 133 QLKVVERTRTATMLCAAS-GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGA 191
Query: 249 LVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDL 285
L + D G+Y C+A+N AG+ + V +L
Sbjct: 192 LQIEQSEESDQGKYECVATNSAGTRYSAPANLYVREL 228
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 57.4 bits (137), Expect = 2e-08
Identities = 61/217 (28%), Positives = 96/217 (44%), Gaps = 31/217 (14%)
Query: 84 RTPVVQEFESVELSCIITDSQTSDPR--IEW----KKIQDEQTTYVFFDNKIQGDLAGRA 137
RTPV Q S ++ I + T DPR I W KK+ +++ + FD+ G
Sbjct: 28 RTPVDQTGVSGGVASFICQA-TGDPRPKIVWNKKGKKVSNQRFEVIEFDD-------GSG 79
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-------PVTPVCR 190
+L L+ T RD A+Y C VA N+ EI + LTV + P +
Sbjct: 80 SVLRIQPLR----TPRDEAIYEC--VASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGP 132
Query: 191 VPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRAN--PRFRNSSFHLNSETGT 248
K V + AT+ C S G+P P +W+++ +P+ T + + R+ S G
Sbjct: 133 QLKVVERTRTATMLCAAS-GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGA 191
Query: 249 LVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDL 285
L + D G+Y C+A+N AG+ + V +L
Sbjct: 192 LQIEQSEESDQGKYECVATNSAGTRYSAPANLYVREL 228
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform
4 precursor [Homo sapiens]
Length = 1501
Score = 57.4 bits (137), Expect = 2e-08
Identities = 61/217 (28%), Positives = 96/217 (44%), Gaps = 31/217 (14%)
Query: 84 RTPVVQEFESVELSCIITDSQTSDPR--IEW----KKIQDEQTTYVFFDNKIQGDLAGRA 137
RTPV Q S ++ I + T DPR I W KK+ +++ + FD+ G
Sbjct: 28 RTPVDQTGVSGGVASFICQA-TGDPRPKIVWNKKGKKVSNQRFEVIEFDD-------GSG 79
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-------PVTPVCR 190
+L L+ T RD A+Y C VA N+ EI + LTV + P +
Sbjct: 80 SVLRIQPLR----TPRDEAIYEC--VASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGP 132
Query: 191 VPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRAN--PRFRNSSFHLNSETGT 248
K V + AT+ C S G+P P +W+++ +P+ T + + R+ S G
Sbjct: 133 QLKVVERTRTATMLCAAS-GNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGA 191
Query: 249 LVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDL 285
L + D G+Y C+A+N AG+ + V +L
Sbjct: 192 LQIEQSEESDQGKYECVATNSAGTRYSAPANLYVREL 228
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 57.0 bits (136), Expect = 3e-08
Identities = 53/191 (27%), Positives = 85/191 (44%), Gaps = 25/191 (13%)
Query: 86 PVVQEFESVELSCIITDSQTS-DPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTS 144
P QEF E + I+ D +S P I WK + D ++ D+ R +L
Sbjct: 124 PTPQEFREGEDAVIVCDVVSSLPPTIIWK--------HKGRDVILKKDV--RFIVLSNNY 173
Query: 145 LKIWNVTRRDSALYRCE--VVARNDRKEIDEIVIELTVQVKPVTPVCR--VPKAVPVGKM 200
L+I + + D YRCE ++AR EI+ I++ V V P + V +G+
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARG---EINFKDIQVIVNVPPTIQARQNIVNATANLGQS 230
Query: 201 ATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSG 260
TL C ++EG P P SW ++ + + + + + ++ L V K+D
Sbjct: 231 VTLVC-DAEGFPEPTMSWTKDGEQIEQEED------DEKYIFSDDSSQLTIKKVDKNDEA 283
Query: 261 QYYCIASNDAG 271
+Y CIA N AG
Sbjct: 284 EYICIAENKAG 294
Score = 45.4 bits (106), Expect = 8e-05
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 26/171 (15%)
Query: 107 DPRIEWKKI------QDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRC 160
+P + W K +++ Y+F D+ Q L I V + D A Y C
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQ--------------LTIKKVDKNDEAEYIC 287
Query: 161 EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR 220
+A N E D I L V KP A+ + + TL C E+ G P P +W
Sbjct: 288 --IAENKAGEQDA-TIHLKVFAKPKITYVENQTAMELEEQVTLTC-EASGDPIPSITWRT 343
Query: 221 NDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAG 271
+ + ++ + H + +L ++ D+G+Y C ASN G
Sbjct: 344 STRNISSEEKTLDGHMVVRSH--ARVSSLTLKSIQYTDAGEYICTASNTIG 392
Score = 31.6 bits (70), Expect = 1.1
Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 29/200 (14%)
Query: 83 NRTPVVQEFESVELSCIITDSQTSDPRIEWK----KIQDEQTTYVFFDNKIQGDLAGRAE 138
N+T + E E V L+C + P I W+ I E+ T + G + R+
Sbjct: 315 NQTAMELE-EQVTLTCEASGDPI--PSITWRTSTRNISSEEKT-------LDGHMVVRSH 364
Query: 139 ILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV- 197
+SL + ++ D+ Y C A N + D + L VQ P + P AV
Sbjct: 365 AR-VSSLTLKSIQYTDAGEYIC--TASNTIGQ-DSQSMYLEVQY---APKLQGPVAVYTW 417
Query: 198 -GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHK 256
G + C E +P SW+R+ LP+ + +N + N+ L T +
Sbjct: 418 EGNQVNITC-EVFAYPSATISWFRDGQLLPSSNYSNIKIYNT-----PSASYLEVTPDSE 471
Query: 257 DDSGQYYCIASNDAGSARCE 276
+D G Y C A N G E
Sbjct: 472 NDFGNYNCTAVNRIGQESLE 491
Score = 30.4 bits (67), Expect = 2.5
Identities = 50/227 (22%), Positives = 83/227 (36%), Gaps = 39/227 (17%)
Query: 109 RIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDR 168
+ EW+ + +E ++D K + + G I+G + Y + A N
Sbjct: 534 KAEWRAVGEEVWHSKWYDAK-EASMEGIVTIVGL----------KPETTYAVRLAALNG- 581
Query: 169 KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMA--------TLHCQESEGHPRPHY---- 216
K + EI + +PV PK G+M L Q+ G P HY
Sbjct: 582 KGLGEISAASEFKTQPVQGEPSAPKLE--GQMGEDGNSIKVNLIKQDDGGSPIRHYLVRY 639
Query: 217 ----SWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
S ++ ++ LP+ S S N+E V + S + + A
Sbjct: 640 RALSSEWKPEIRLPSGS---DHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQP 696
Query: 273 ARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFIN 319
L+ G I+G +L+V+ VL L+ + I C YF+N
Sbjct: 697 TAIPANGSPTSGLSTGAIVG-ILIVIFVLLLVVVDITC-----YFLN 737
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 57.0 bits (136), Expect = 3e-08
Identities = 53/191 (27%), Positives = 85/191 (44%), Gaps = 25/191 (13%)
Query: 86 PVVQEFESVELSCIITDSQTS-DPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTS 144
P QEF E + I+ D +S P I WK + D ++ D+ R +L
Sbjct: 124 PTPQEFREGEDAVIVCDVVSSLPPTIIWK--------HKGRDVILKKDV--RFIVLSNNY 173
Query: 145 LKIWNVTRRDSALYRCE--VVARNDRKEIDEIVIELTVQVKPVTPVCR--VPKAVPVGKM 200
L+I + + D YRCE ++AR EI+ I++ V V P + V +G+
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARG---EINFKDIQVIVNVPPTIQARQNIVNATANLGQS 230
Query: 201 ATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSG 260
TL C ++EG P P SW ++ + + + + + ++ L V K+D
Sbjct: 231 VTLVC-DAEGFPEPTMSWTKDGEQIEQEED------DEKYIFSDDSSQLTIKKVDKNDEA 283
Query: 261 QYYCIASNDAG 271
+Y CIA N AG
Sbjct: 284 EYICIAENKAG 294
Score = 45.4 bits (106), Expect = 8e-05
Identities = 43/179 (24%), Positives = 72/179 (40%), Gaps = 32/179 (17%)
Query: 107 DPRIEWKKI------QDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRC 160
+P + W K +++ Y+F D+ Q L I V + D A Y C
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQ--------------LTIKKVDKNDEAEYIC 287
Query: 161 EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR 220
+A N E D I L V KP A+ + + TL C E+ G P P +W
Sbjct: 288 --IAENKAGEQDA-TIHLKVFAKPKITYVENQTAMELEEQVTLTC-EASGDPIPSITWRT 343
Query: 221 NDVPLPTDSRAN----PRFRNSSFHL----NSETGTLVFTAVHKDDSGQYYCIASNDAG 271
+ + ++ +A+ + H+ ++ +L ++ D+G+Y C ASN G
Sbjct: 344 STRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 402
Score = 31.6 bits (70), Expect = 1.1
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 23/178 (12%)
Query: 101 TDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRC 160
T + +S+ + W + + ++T + G + R+ +SL + ++ D+ Y C
Sbjct: 345 TRNISSEEKASWTRPEKQET--------LDGHMVVRSHAR-VSSLTLKSIQYTDAGEYIC 395
Query: 161 EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--GKMATLHCQESEGHPRPHYSW 218
A N + D + L VQ P + P AV G + C E +P SW
Sbjct: 396 --TASNTIGQ-DSQSMYLEVQY---APKLQGPVAVYTWEGNQVNITC-EVFAYPSATISW 448
Query: 219 YRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCE 276
+R+ LP+ + +N + N+ L T ++D G Y C A N G E
Sbjct: 449 FRDGQLLPSSNYSNIKIYNT-----PSASYLEVTPDSENDFGNYNCTAVNRIGQESLE 501
Score = 30.4 bits (67), Expect = 2.5
Identities = 50/227 (22%), Positives = 83/227 (36%), Gaps = 39/227 (17%)
Query: 109 RIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDR 168
+ EW+ + +E ++D K + + G I+G + Y + A N
Sbjct: 544 KAEWRAVGEEVWHSKWYDAK-EASMEGIVTIVGL----------KPETTYAVRLAALNG- 591
Query: 169 KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMA--------TLHCQESEGHPRPHY---- 216
K + EI + +PV PK G+M L Q+ G P HY
Sbjct: 592 KGLGEISAASEFKTQPVQGEPSAPKLE--GQMGEDGNSIKVNLIKQDDGGSPIRHYLVRY 649
Query: 217 ----SWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
S ++ ++ LP+ S S N+E V + S + + A
Sbjct: 650 RALSSEWKPEIRLPSGS---DHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQP 706
Query: 273 ARCEEQEMEVYDLNIGGIIGGVLVVLAVLALITLGICCAYRRGYFIN 319
L+ G I+G +L+V+ VL L+ + I C YF+N
Sbjct: 707 TAIPANGSPTSGLSTGAIVG-ILIVIFVLLLVVVDITC-----YFLN 747
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 57.0 bits (136), Expect = 3e-08
Identities = 53/191 (27%), Positives = 85/191 (44%), Gaps = 25/191 (13%)
Query: 86 PVVQEFESVELSCIITDSQTS-DPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTS 144
P QEF E + I+ D +S P I WK + D ++ D+ R +L
Sbjct: 124 PTPQEFREGEDAVIVCDVVSSLPPTIIWK--------HKGRDVILKKDV--RFIVLSNNY 173
Query: 145 LKIWNVTRRDSALYRCE--VVARNDRKEIDEIVIELTVQVKPVTPVCR--VPKAVPVGKM 200
L+I + + D YRCE ++AR EI+ I++ V V P + V +G+
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARG---EINFKDIQVIVNVPPTIQARQNIVNATANLGQS 230
Query: 201 ATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSG 260
TL C ++EG P P SW ++ + + + + + ++ L V K+D
Sbjct: 231 VTLVC-DAEGFPEPTMSWTKDGEQIEQEED------DEKYIFSDDSSQLTIKKVDKNDEA 283
Query: 261 QYYCIASNDAG 271
+Y CIA N AG
Sbjct: 284 EYICIAENKAG 294
Score = 45.4 bits (106), Expect = 8e-05
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 26/171 (15%)
Query: 107 DPRIEWKKI------QDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRC 160
+P + W K +++ Y+F D+ Q L I V + D A Y C
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQ--------------LTIKKVDKNDEAEYIC 287
Query: 161 EVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR 220
+A N E D I L V KP A+ + + TL C E+ G P P +W
Sbjct: 288 --IAENKAGEQDA-TIHLKVFAKPKITYVENQTAMELEEQVTLTC-EASGDPIPSITWRT 343
Query: 221 NDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAG 271
+ + ++ + H + +L ++ D+G+Y C ASN G
Sbjct: 344 STRNISSEEKTLDGHMVVRSH--ARVSSLTLKSIQYTDAGEYICTASNTIG 392
Score = 31.6 bits (70), Expect = 1.1
Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 29/200 (14%)
Query: 83 NRTPVVQEFESVELSCIITDSQTSDPRIEWK----KIQDEQTTYVFFDNKIQGDLAGRAE 138
N+T + E E V L+C + P I W+ I E+ T + G + R+
Sbjct: 315 NQTAMELE-EQVTLTCEASGDPI--PSITWRTSTRNISSEEKT-------LDGHMVVRSH 364
Query: 139 ILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV- 197
+SL + ++ D+ Y C A N + D + L VQ P + P AV
Sbjct: 365 AR-VSSLTLKSIQYTDAGEYIC--TASNTIGQ-DSQSMYLEVQY---APKLQGPVAVYTW 417
Query: 198 -GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHK 256
G + C E +P SW+R+ LP+ + +N + N+ L T +
Sbjct: 418 EGNQVNITC-EVFAYPSATISWFRDGQLLPSSNYSNIKIYNT-----PSASYLEVTPDSE 471
Query: 257 DDSGQYYCIASNDAGSARCE 276
+D G Y C A N G E
Sbjct: 472 NDFGNYNCTAVNRIGQESLE 491
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 56.6 bits (135), Expect = 3e-08
Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)
Query: 78 NLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRA 137
N+K ++ V+ +S L CI T PRI W+K D + R
Sbjct: 3714 NIKGGPQSLVILLNKSTVLECIAEGVPT--PRITWRK-----------DGAVLAGNHARY 3760
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVV--ARNDRKEIDEIVIELTVQVKPVTPVCRVPKAV 195
IL L I + D+ Y C A DR+ ID L V V P V
Sbjct: 3761 SILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRID-----LQVHVPPSIAPGPTNMTV 3815
Query: 196 PVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVH 255
V TL C E+ G P+P +W +N L D N S+ L S +G+LV +
Sbjct: 3816 IVNVQTTLAC-EATGIPKPSINWRKNGHLLNVDQNQN------SYRLLS-SGSLVIISPS 3867
Query: 256 KDDSGQYYCIASNDAG 271
DD+ Y C +N AG
Sbjct: 3868 VDDTATYECTVTNGAG 3883
Score = 56.2 bits (134), Expect = 4e-08
Identities = 59/197 (29%), Positives = 79/197 (40%), Gaps = 36/197 (18%)
Query: 79 LKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGR-- 136
++S+ V E L C+ T P I WKK DN + +L G+
Sbjct: 4171 IRSTEGHYTVNENSQAILPCVADGIPT--PAINWKK-----------DNVLLANLLGKYT 4217
Query: 137 AEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVP 196
AE G+ L+ NV DS Y C VA N E D + LTV V P ++
Sbjct: 4218 AEPYGELILE--NVVLEDSGFYTC--VANNAAGE-DTHTVSLTVHVLPTFTELPGDVSLN 4272
Query: 197 VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETG--TLVFTAV 254
G+ L C+ + G P P +W N+ +P H +S G LV V
Sbjct: 4273 KGEQLRLSCKAT-GIPLPKLTWTFNNNIIPA-------------HFDSVNGHSELVIERV 4318
Query: 255 HKDDSGQYYCIASNDAG 271
K+DSG Y C A N G
Sbjct: 4319 SKEDSGTYVCTAENSVG 4335
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/177 (25%), Positives = 73/177 (41%), Gaps = 28/177 (15%)
Query: 96 LSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDS 155
L+C + T P I+W + + +++ R LG SL I+ D+
Sbjct: 4369 LNCEVKGDPT--PTIQWNR------------KGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 156 ALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPH 215
Y C VA N+ ++ + LT+Q P+ + V + G L+CQ + G P+P
Sbjct: 4415 GDYTC--VATNEAGVVERSM-SLTLQSPPIITLEPVETVINAGGKIILNCQAT-GEPQPT 4470
Query: 216 YSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
+W R + D R N NS L K+D+ ++ C+A N GS
Sbjct: 4471 ITWSRQGHSISWDDRVNVLSNNS----------LYIADAQKEDTSEFECVARNLMGS 4517
Score = 51.6 bits (122), Expect = 1e-06
Identities = 55/200 (27%), Positives = 81/200 (40%), Gaps = 31/200 (15%)
Query: 78 NLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRA 137
N+ S+ + E +S + S P + WKK T D GR
Sbjct: 2196 NIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT----------DSMGRV 2245
Query: 138 EIL-GKTSLKIWNVTRRDSALYRCEV--VARNDRKEIDEIVIELTVQVKP-VTPVCRVPK 193
IL G L+I + D+ALY C VA +KE + L V ++P +T P
Sbjct: 2246 RILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYN-----LQVYIRPTITNSGSHPT 2300
Query: 194 AVPV--GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVF 251
+ V GK +L C E +G P P +W ++ PL + + E L
Sbjct: 2301 EIIVTRGKSISLEC-EVQGIPPPTVTWMKDGHPL---------IKAKGVEILDEGHILQL 2350
Query: 252 TAVHKDDSGQYYCIASNDAG 271
+H D+G+Y C+A N AG
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAG 2370
Score = 49.7 bits (117), Expect = 4e-06
Identities = 50/187 (26%), Positives = 75/187 (40%), Gaps = 30/187 (16%)
Query: 92 ESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVT 151
E V L C + P I W K + ++ + R L S+KI
Sbjct: 1095 EEVTLPCEV--KSLPPPIITWAK-----------ETQLISPFSPRHTFLPSGSMKITETR 1141
Query: 152 RRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPK--AVPVGKMATLHCQESE 209
DS +Y C VA N + + V +L V V P + R PK V VG+ + C ++
Sbjct: 1142 TSDSGMYLC--VATNIAGNVTQAV-KLNVHVPP--KIQRGPKHLKVQVGQRVDIPCN-AQ 1195
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASND 269
G P P +W + + D H+++ GTL D+G Y C+A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGE---------HHVSNPDGTLSIDQATPSDAGIYTCVATNI 1246
Query: 270 AGSARCE 276
AG+ E
Sbjct: 1247 AGTDETE 1253
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/170 (28%), Positives = 70/170 (41%), Gaps = 27/170 (15%)
Query: 105 TSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAE-ILGKTSLKIWNVTRRDSALYRCEVV 163
T P I W+K I + +GR +L L+I R D+ Y C V
Sbjct: 4014 TPSPFITWQK------------EGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMC--V 4059
Query: 164 ARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDV 223
A+N I+L VQV PV + V K TL C E++G P P +W+++
Sbjct: 4060 AQNPAGTALG-KIKLNVQVPPVISPHLKEYVIAVDKPITLSC-EADGLPPPDITWHKDGR 4117
Query: 224 PLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
+ R +G+L V D+G Y C+A+N AGS+
Sbjct: 4118 AIVESIRQRVL----------SSGSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Score = 47.8 bits (112), Expect = 2e-05
Identities = 48/184 (26%), Positives = 74/184 (40%), Gaps = 30/184 (16%)
Query: 94 VELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRR 153
+EL C +T S P I W K D ++ + G +L L I
Sbjct: 1752 LELDCHVTGSPP--PTIMWLK-----------DGQLIDERDGFKILLNGRKLVIAQAQVS 1798
Query: 154 DSALYRCEVV--ARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVG-KMATLHCQESEG 210
++ LYRC A + +KE E+TV V P + + V V K L C + G
Sbjct: 1799 NTGLYRCMAANTAGDHKKEF-----EVTVHVPPTIKSSGLSERVVVKYKPVALQCI-ANG 1852
Query: 211 HPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDA 270
P P +W ++D P+ T + + S L +D+G+Y C+A+N A
Sbjct: 1853 IPNPSITWLKDDQPVNT--------AQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAA 1904
Query: 271 GSAR 274
G +
Sbjct: 1905 GETQ 1908
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 14/156 (8%)
Query: 117 DEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVI 176
D T+ D ++ R L SL++ +V D+ Y C V + +
Sbjct: 548 DYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAAS---V 604
Query: 177 ELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFR 236
LTVQ P V ++ G ++ C + G+P+P +W ND+ + + R+R
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT-GYPKPKIAWTVNDMFIV----GSHRYR 659
Query: 237 NSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
+S GTL D+G Y C+ASN AG+
Sbjct: 660 MTS------DGTLFIKNAAPKDAGIYGCLASNSAGT 689
Score = 47.0 bits (110), Expect = 3e-05
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 13/130 (10%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEID-EIVIELTVQVKPVTPVCRVPKAVPVGKMAT 202
+L I N+ D Y CE A N +I E + +T V P+ + V G+ T
Sbjct: 851 ALFILNLWASDKGTYICE--AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLT 908
Query: 203 LHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQY 262
L C G+P P W +N L +N + S+ G+L V D G+Y
Sbjct: 909 LPCTLLAGNPIPERRWIKNSAML---------LQNPYITVRSD-GSLHIERVQLQDGGEY 958
Query: 263 YCIASNDAGS 272
C+ASN AG+
Sbjct: 959 TCVASNVAGT 968
Score = 45.1 bits (105), Expect = 1e-04
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 27/155 (17%)
Query: 141 GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRV------PKA 194
G +L+I N ++ Y C VA N+ E+ + E+ V + P+ + PK
Sbjct: 2627 GGRTLQILNAQEDNAGRYSC--VATNEAGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKE 2683
Query: 195 VP--VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFT 252
V V TL C E+ P SWY++ PL +D N + + TL
Sbjct: 2684 VKIKVNNTLTLEC-EAYAIPSASLSWYKDGQPLKSDDHVN---------IAANGHTLQIK 2733
Query: 253 AVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNI 287
D+G+Y C+ASN AG E E++ +D+NI
Sbjct: 2734 EAQISDTGRYTCVASNIAG-----EDELD-FDVNI 2762
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 142 KTSLKIWNVTRRDSALYRCEV--VARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGK 199
++ LKI + +D+ Y CE VA K + + I + + + ++ V G
Sbjct: 2156 RSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYN-VNIWVPPNIGGSDELTQL--TVIEGN 2212
Query: 200 MATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDS 259
+ +L C ES G P P+ W + P+ TDS R + L + K D+
Sbjct: 2213 LISLLC-ESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQ-------ISIAEKSDA 2264
Query: 260 GQYYCIASNDAGSARCEEQEMEVY 283
Y C+ASN AG+A+ +E ++VY
Sbjct: 2265 ALYSCVASNVAGTAK-KEYNLQVY 2287
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/138 (30%), Positives = 61/138 (44%), Gaps = 17/138 (12%)
Query: 141 GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCR--VPKAVPV- 197
G L+I D+ Y C VA N+ E D + ++ V V P+ +P+ V V
Sbjct: 2829 GGRVLQIPRAKVEDAGRYTC--VAVNEAGE-DSLQYDVRVLVPPIIKGANSDLPEEVTVL 2885
Query: 198 -GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHK 256
K A + C S G P P SW ++ PL D + F N ++ T +
Sbjct: 2886 VNKSALIECLSS-GSPAPRNSWQKDGQPLLEDD-------HHKFLSNGRILQILNTQI-- 2935
Query: 257 DDSGQYYCIASNDAGSAR 274
D G+Y C+A N AGSA+
Sbjct: 2936 TDIGRYVCVAENTAGSAK 2953
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/149 (25%), Positives = 64/149 (42%), Gaps = 19/149 (12%)
Query: 141 GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--G 198
G + L+I DS Y C +A N + + L++QV P +P V V G
Sbjct: 3205 GGSKLQIARSQHSDSGNYTC--IASNMEGKAQKYYF-LSIQVPPSVAGAEIPSDVSVLLG 3261
Query: 199 KMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
+ L C + G P P W ++ P+ + R +++ TL D
Sbjct: 3262 ENVELVCN-ANGIPTPLIQWLKDGKPIASGETERIR-------VSANGSTLNIYGALTSD 3313
Query: 259 SGQYYCIASNDAGSARCEEQEMEVYDLNI 287
+G+Y C+A+N AG +E +++LN+
Sbjct: 3314 TGKYTCVATNPAG------EEDRIFNLNV 3336
Score = 43.5 bits (101), Expect = 3e-04
Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 34/184 (18%)
Query: 93 SVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTS-LKIWNVT 151
S+ + C T T P+I W K N + L+ +L ++I
Sbjct: 3359 SINIECRATG--TPPPQINWLK------------NGLPLPLSSHIRLLAAGQVIRIVRAQ 3404
Query: 152 RRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--GKMATLHCQESE 209
D A+Y C VA N R +D L V P + + V G ++ C ++
Sbjct: 3405 VSDVAVYTC--VASN-RAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACI-TD 3460
Query: 210 GHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAV--HKDDSGQYYCIAS 267
G P P +W R+ PL D+ HL T +V + +DSG+Y CIAS
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDA-----------HLTVSTHGMVLQLLKAETEDSGKYTCIAS 3509
Query: 268 NDAG 271
N+AG
Sbjct: 3510 NEAG 3513
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 14/140 (10%)
Query: 136 RAEIL-GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKA 194
R IL G L+I N D+A Y C V + K E + LTV V P
Sbjct: 3667 RVRILSGGRYLQINNADLGDTANYTC-VASNIAGKTTREFI--LTVNVPPNIKGGPQSLV 3723
Query: 195 VPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAV 254
+ + K L C +EG P P +W ++ L + N H+ S
Sbjct: 3724 ILLNKSTVLECI-AEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS---------A 3773
Query: 255 HKDDSGQYYCIASNDAGSAR 274
H D+G+Y C+A+N AG+ R
Sbjct: 3774 HVTDTGRYLCMATNAAGTDR 3793
Score = 42.0 bits (97), Expect = 8e-04
Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 15/131 (11%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPK--AVPVGKMAT 202
L + N R D Y+C V ++ D I+LT+ + P V +V + +
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAGKQAKD---IKLTIYIPPSIKGGNVTTDISVLINSLIK 1566
Query: 203 LHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQY 262
L C E+ G P P +WY++ P+ + S+A + H+ DS Y
Sbjct: 1567 LEC-ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHI---------PRAQVSDSATY 1616
Query: 263 YCIASNDAGSA 273
C +N AG+A
Sbjct: 1617 TCHVANVAGTA 1627
Score = 42.0 bits (97), Expect = 8e-04
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 19/143 (13%)
Query: 154 DSALYRCEV--VARNDRKEID-EIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEG 210
DSA Y C V VA K ++ + ++ TP+ K V + TL C+ + G
Sbjct: 1612 DSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPL---NKQVVIAHSLTLECKAA-G 1667
Query: 211 HPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDA 270
+P P +W ++ VP+ N + + + L + + D GQY C+A++ A
Sbjct: 1668 NPSPILTWLKDGVPVKA---------NDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVA 1718
Query: 271 GSARCEEQEMEVYDLNIGGIIGG 293
G +E + EV L I GG
Sbjct: 1719 GE---KEIKYEVDVLVPPAIEGG 1738
Score = 42.0 bits (97), Expect = 8e-04
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 13/130 (10%)
Query: 154 DSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPR 213
D+ +Y+C + + E+ L V V P AV V L C E+ G P
Sbjct: 1985 DAGIYKCVAI---NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 214 PHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
P +W ++ P+ + S + + S L T+ D+G+Y C+A N AG
Sbjct: 2041 PSLTWLKDGSPVSSFS--------NGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEK 2092
Query: 274 RCEEQEMEVY 283
+ + ++ VY
Sbjct: 2093 Q-RDIDLRVY 2101
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/134 (29%), Positives = 56/134 (41%), Gaps = 19/134 (14%)
Query: 141 GKTSLKIWNVTRRDSALYRCEVVARNDR---KEIDEIVIELTVQVKPVTPVCRVPKAVPV 197
G + L I V++ DS Y C A N K I + ++ K P + P+
Sbjct: 4309 GHSELVIERVSKEDSGTYVC--TAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE---PL 4363
Query: 198 GKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKD 257
G A L+C E +G P P W R V D + R R G+L +
Sbjct: 4364 GGNAILNC-EVKGDPTPTIQWNRKGV----DIEISHRIRQLG------NGSLAIYGTVNE 4412
Query: 258 DSGQYYCIASNDAG 271
D+G Y C+A+N+AG
Sbjct: 4413 DAGDYTCVATNEAG 4426
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/205 (23%), Positives = 84/205 (40%), Gaps = 40/205 (19%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKK----IQDEQTTYVFFDNKIQGDLAGRAEILGKT 143
V+E +SV L+C +T + P I W K +Q+++ ++ I G
Sbjct: 2491 VKEKQSVTLTCEVTGNPV--PEITWHKDGQPLQEDEAHHI---------------ISGGR 2533
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRV---PKAVPV--G 198
L+I NV + Y C + K L V V P P+ V V
Sbjct: 2534 FLQITNVQVPHTGRYTCLASSPAGHKSRS---FSLNVFVSPTIAGVGSDGNPEDVTVILN 2590
Query: 199 KMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
+L C E+ +P +W+++ PL + N + + TL +D+
Sbjct: 2591 SPTSLVC-EAYSYPPATITWFKDGTPLES---------NRNIRILPGGRTLQILNAQEDN 2640
Query: 259 SGQYYCIASNDAGSARCEEQEMEVY 283
+G+Y C+A+N+AG + E++VY
Sbjct: 2641 AGRYSCVATNEAGE-MIKHYEVKVY 2664
Score = 40.0 bits (92), Expect = 0.003
Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 19/138 (13%)
Query: 144 SLKIWNVTRRDSALYRCEVVARN---DRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKM 200
SL I V +D Y C VA N + +V+ + ++ + + +PV
Sbjct: 944 SLHIERVQLQDGGEYTC--VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV--- 998
Query: 201 ATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSG 260
TL C+ S G+P+P W + + T S + S ++ S G ++SG
Sbjct: 999 -TLPCKAS-GNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---------EESG 1047
Query: 261 QYYCIASNDAGSARCEEQ 278
+Y C A+N AG A+ + Q
Sbjct: 1048 EYVCTATNTAGYAKRKVQ 1065
Score = 40.0 bits (92), Expect = 0.003
Identities = 54/214 (25%), Positives = 77/214 (35%), Gaps = 25/214 (11%)
Query: 76 AVNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAG 135
A ++ SN V V L C P + W K + + F N +Q G
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLK---DGSPVSSFSNGLQVLSGG 2065
Query: 136 RAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAV 195
R IL TS +I D+ Y C V K+ D I+L V V P +V
Sbjct: 2066 R--ILALTSAQI-----SDTGRYTCVAVNAAGEKQRD---IDLRVYVPPNIMGEEQNVSV 2115
Query: 196 PVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVH 255
+ + L CQ S+ P P +W ++ PL + ++ L
Sbjct: 2116 LISQAVELLCQ-SDAIPPPTLTWLKDGHPL---------LKKPGLSISENRSVLKIEDAQ 2165
Query: 256 KDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGG 289
D+G+Y C A+N AG NIGG
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGG 2199
Score = 38.9 bits (89), Expect = 0.007
Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 19/133 (14%)
Query: 144 SLKIWNVTRRDSALYRCEVV--ARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMA 201
+L I N +D+ +Y C A D++ IE P V + V +G +
Sbjct: 665 TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEA-----PKLMVVQSELLVALGDIT 719
Query: 202 TLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHL-NSETGTLVFTAVHKDDSG 260
+ C+ S G P P W++ D+ L R S+F + + G L D+G
Sbjct: 720 VMECKTS-GIPPPQVKWFKGDLEL----------RPSTFLIIDPLLGLLKIQETQDLDAG 768
Query: 261 QYYCIASNDAGSA 273
Y C+A N+AG A
Sbjct: 769 DYTCVAINEAGRA 781
Score = 37.4 bits (85), Expect = 0.021
Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 13/135 (9%)
Query: 139 ILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVG 198
IL +++I + Y C VARN V L V PV V +
Sbjct: 3946 ILSSGAIEILATQLNHAGRYTC--VARNAAGSAHRHVT-LHVHEPPVIQPQPSELHVILN 4002
Query: 199 KMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
L C E+ G P P +W + + + T R H +G L + ++D
Sbjct: 4003 NPILLPC-EATGTPSPFITWQKEGINVNTSGRN---------HAVLPSGGLQISRAVRED 4052
Query: 259 SGQYYCIASNDAGSA 273
+G Y C+A N AG+A
Sbjct: 4053 AGTYMCVAQNPAGTA 4067
Score = 37.0 bits (84), Expect = 0.027
Identities = 38/131 (29%), Positives = 51/131 (38%), Gaps = 14/131 (10%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKP-VTPVCRVPKAVPVGKMATL 203
L+I N D Y C VA N + L V V P V V V +L
Sbjct: 2928 LQILNTQITDIGRYVC--VAENTAGSAKKY-FNLNVHVPPSVIGPKSENLTVVVNNFISL 2984
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C+ S G P P SW +N+ P+ N++ + TL D G+Y
Sbjct: 2985 TCEVS-GFPPPDLSWLKNEQPIKL---------NTNTLIVPGGRTLQIIRAKVSDGGEYT 3034
Query: 264 CIASNDAGSAR 274
CIA N AG ++
Sbjct: 3035 CIAINQAGESK 3045
Score = 36.6 bits (83), Expect = 0.035
Identities = 36/133 (27%), Positives = 51/133 (38%), Gaps = 15/133 (11%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
+L I T D+ +Y C VA N DE I L VQ P P +
Sbjct: 1225 TLSIDQATPSDAGIYTC--VATNIAGT-DETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 204 HCQE----SEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDS 259
E ++G P+P W N L R + + LV +V D+
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTG--------REPGISILEDGTLLVIASVTPYDN 1333
Query: 260 GQYYCIASNDAGS 272
G+Y C+A N+AG+
Sbjct: 1334 GEYICVAVNEAGT 1346
Score = 36.2 bits (82), Expect = 0.046
Identities = 46/171 (26%), Positives = 65/171 (38%), Gaps = 24/171 (14%)
Query: 108 PRIEWKK--IQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVAR 165
P+++W K ++ +T++ D +LG LKI D+ Y C +
Sbjct: 731 PQVKWFKGDLELRPSTFLIID-----------PLLGL--LKIQETQDLDAGDYTCVAINE 777
Query: 166 NDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPL 225
R I L V PV ++ +G TL C +G+P P W R D +
Sbjct: 778 AGRATGK---ITLDVGSPPVFIQEPADVSMEIGSNVTLPCYV-QGYPEPTIKWRRLD-NM 832
Query: 226 PTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCE 276
P SR F SS TG L + D G Y C A N G + E
Sbjct: 833 PIFSRP---FSVSSIS-QLRTGALFILNLWASDKGTYICEAENQFGKIQSE 879
Score = 36.2 bits (82), Expect = 0.046
Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 19/136 (13%)
Query: 143 TSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTP----VCRVPKAVPVG 198
T L I +VT D+ Y C V + E L V V PV V V +V +
Sbjct: 1321 TLLVIASVTPYDNGEYICVAV---NEAGTTERKYNLKVHVPPVIKDKEQVTNV--SVLLN 1375
Query: 199 KMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
++ L C E EG P P WY+++V + T+S N L +D
Sbjct: 1376 QLTNLFC-EVEGTPSPIIMWYKDNVQV-TESSTIQTVNNGKI--------LKLFRATPED 1425
Query: 259 SGQYYCIASNDAGSAR 274
+G+Y C A N AG+++
Sbjct: 1426 AGRYSCKAINIAGTSQ 1441
Score = 35.0 bits (79), Expect = 0.10
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 18/133 (13%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--GKMA 201
+L I VT D Y C V+ V PV +VP V V G+ A
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGRAQTFF-----DVSEPPPVIQVPNNVTVTPGERA 537
Query: 202 TLHCQESEGHPRPHYSWYRNDVPLPTDSRANPR-FRNSSFHLNSETGTLVFTAVHKDDSG 260
L C + +W RND + A R N S L S V +D+G
Sbjct: 538 VLTCLIISAVDY-NLTWQRNDRDVRLAEPARIRTLANLSLELKS---------VKFNDAG 587
Query: 261 QYYCIASNDAGSA 273
+Y+C+ S++ GS+
Sbjct: 588 EYHCMVSSEGGSS 600
Score = 35.0 bits (79), Expect = 0.10
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 18/105 (17%)
Query: 176 IELTVQVKP--------VTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPT 227
++LTV V+P ++ V +V G+ TL C E + P P +W + +
Sbjct: 1064 VQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPC-EVKSLPPPIITWAKETQLI-- 1120
Query: 228 DSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGS 272
S +PR H +G++ T DSG Y C+A+N AG+
Sbjct: 1121 -SPFSPR------HTFLPSGSMKITETRTSDSGMYLCVATNIAGN 1158
Score = 34.7 bits (78), Expect = 0.13
Identities = 35/140 (25%), Positives = 57/140 (40%), Gaps = 25/140 (17%)
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPV------------TPVCRV 191
+L+I D+ Y C VA N E DE+ ++ +QV P T
Sbjct: 2729 TLQIKEAQISDTGRYTC--VASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785
Query: 192 PKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVF 251
K V + +L+C E+ P P +WY++ PL + + + L
Sbjct: 2786 AKDVIINNPISLYC-ETNAAPPPTLTWYKDGHPLTSSDKV---------LILPGGRVLQI 2835
Query: 252 TAVHKDDSGQYYCIASNDAG 271
+D+G+Y C+A N+AG
Sbjct: 2836 PRAKVEDAGRYTCVAVNEAG 2855
Score = 34.3 bits (77), Expect = 0.17
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 22/136 (16%)
Query: 145 LKIWNVTRRDSALYRC---EVVARNDRKEIDEIVIELTVQVKP-VTPVCRVPKAVPVGKM 200
L++ N+ D+ Y C V D+K +L+V P + R P+ + V +
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKK------YDLSVHAPPSIIGNHRSPENISVVEK 2401
Query: 201 --ATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
+L C E+ G P P +W+++ P+ ++S + S L +D
Sbjct: 2402 NSVSLTC-EASGIPLPSITWFKDGWPVSL---------SNSVRILSGGRMLRLMQTTMED 2451
Query: 259 SGQYYCIASNDAGSAR 274
+GQY C+ N AG R
Sbjct: 2452 AGQYTCVVRNAAGEER 2467
Score = 33.9 bits (76), Expect = 0.23
Identities = 43/191 (22%), Positives = 62/191 (32%), Gaps = 31/191 (16%)
Query: 88 VQEFESVELSCIITDSQTSDPRIEWKK----IQDEQTTYVFFDNKIQGDLAGRAEILGKT 143
V+E SV L C + P I W K I + + D ++ G+
Sbjct: 3071 VREGTSVSLEC--ESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQY 3128
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
+ NV RD + V + + VI T+ PVT C
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETIS-NPVTLTC-------------- 3173
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
++ G P P +W +N + R + L DSG Y
Sbjct: 3174 ---DATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ-------IARSQHSDSGNYT 3223
Query: 264 CIASNDAGSAR 274
CIASN G A+
Sbjct: 3224 CIASNMEGKAQ 3234
Score = 32.7 bits (73), Expect = 0.51
Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 15/138 (10%)
Query: 141 GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--G 198
G L+I D+ Y C +A + + D+ + + V V P P+ + V
Sbjct: 3580 GGEVLRISTAQVEDTGRYTC--LASSPAGDDDKEYL-VRVHVPPNIAGTDEPRDITVLRN 3636
Query: 199 KMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDD 258
+ TL C+ S+ P P +W RN L +A PR R + S L D
Sbjct: 3637 RQVTLECK-SDAVPPPVITWLRNGERL----QATPRVR-----ILSGGRYLQINNADLGD 3686
Query: 259 SGQYYCIASNDAGSARCE 276
+ Y C+ASN AG E
Sbjct: 3687 TANYTCVASNIAGKTTRE 3704
Score = 31.6 bits (70), Expect = 1.1
Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 13/128 (10%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPK-AVPVGKMATL 203
L++ DS Y C +A N+ E+ + I ++ + + +V V L
Sbjct: 3491 LQLLKAETEDSGKYTC--IASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLEL 3548
Query: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
C S G P P +W ++ PLP + +++ +D+G+Y
Sbjct: 3549 TCIAS-GIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRIST---------AQVEDTGRYT 3598
Query: 264 CIASNDAG 271
C+AS+ AG
Sbjct: 3599 CLASSPAG 3606
>gi|15147240 brother of CDO [Homo sapiens]
Length = 1114
Score = 56.6 bits (135), Expect = 3e-08
Identities = 58/197 (29%), Positives = 81/197 (41%), Gaps = 31/197 (15%)
Query: 84 RTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKT 143
+T +V + +S+ L C+ S PR+ W K T Y NK + L+
Sbjct: 238 QTIIVTKGQSLILECVA--SGIPPPRVTWAKDGSSVTGY----NKTRFLLS--------- 282
Query: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQV--KPVTPVCRVPKAVPVGKMA 201
+L I + DS YRC +A N + VI VQV P + +P G+ A
Sbjct: 283 NLLIDTTSEEDSGTYRC--MADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSA 340
Query: 202 TLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQ 261
L C E G+P P W RN VPL + R L L ++ +D G
Sbjct: 341 KLTC-EVRGNPPPSVLWLRNAVPLISSQR-----------LRLSRRALRVLSMGPEDEGV 388
Query: 262 YYCIASNDAGSARCEEQ 278
Y C+A N+ GSA Q
Sbjct: 389 YQCMAENEVGSAHAVVQ 405
Score = 28.5 bits (62), Expect = 9.6
Identities = 12/26 (46%), Positives = 17/26 (65%)
Query: 247 GTLVFTAVHKDDSGQYYCIASNDAGS 272
GTLV TA++ G+Y C+A AG+
Sbjct: 89 GTLVITALNNHTVGRYQCVARMPAGA 114
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 56.2 bits (134), Expect = 4e-08
Identities = 60/202 (29%), Positives = 92/202 (45%), Gaps = 36/202 (17%)
Query: 84 RTPVVQEFESVELSCIITDSQTSDPR--IEW----KKIQDEQTTYVFFDNKIQGDLAGRA 137
RTPV Q S ++ I + T DPR I W KK+ +++ + FD+ G
Sbjct: 28 RTPVDQTGVSGGVASFICQA-TGDPRPKIVWNKKGKKVSNQRFEVIEFDD-------GSG 79
Query: 138 EILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVK-------PVTPVCR 190
+L L+ T RD A+Y C VA N+ EI + LTV + P +
Sbjct: 80 SVLRIQPLR----TPRDEAIYEC--VASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGP 132
Query: 191 VPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLV 250
K V + AT+ C S G+P P +W+++ +P+ T S N R + +G L
Sbjct: 133 QLKVVERTRTATMLCAAS-GNPDPEITWFKDFLPVDT-SNNNGRIKQL------RSGALQ 184
Query: 251 FTAVHKDDSGQYYCIASNDAGS 272
+ D G+Y C+A+N AG+
Sbjct: 185 IEQSEESDQGKYECVATNSAGT 206
>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
Length = 869
Score = 55.8 bits (133), Expect = 6e-08
Identities = 46/140 (32%), Positives = 66/140 (47%), Gaps = 17/140 (12%)
Query: 145 LKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPV--GKMAT 202
L I +V D +Y C A N E L V++KP + R P V + G A
Sbjct: 84 LTILSVEDSDDGIYCC--TANNGVGGAVESCGALQVKMKP--KITRPPINVKIIEGLKAV 139
Query: 203 LHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQY 262
L C + G+P+P SW + D PL +SR E+G+L V K+D+GQY
Sbjct: 140 LPCT-TMGNPKPSVSWIKGDSPLRENSRIAVL----------ESGSLRIHNVQKEDAGQY 188
Query: 263 YCIASNDAGSARCEEQEMEV 282
C+A N G+A + ++EV
Sbjct: 189 RCVAKNSLGTAYSKVVKLEV 208
Score = 36.2 bits (82), Expect = 0.046
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 12/93 (12%)
Query: 184 PVTPVCRVPKAVP---VGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSF 240
P PV P V ++AT C E +P+P SW RN + + + ++ +
Sbjct: 25 PKAPVITTPLETVDALVEEVATFMCAV-ESYPQPEISWTRNKILI--------KLFDTRY 75
Query: 241 HLNSETGTLVFTAVHKDDSGQYYCIASNDAGSA 273
+ L +V D G Y C A+N G A
Sbjct: 76 SIRENGQLLTILSVEDSDDGIYCCTANNGVGGA 108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,200,769
Number of Sequences: 37866
Number of extensions: 653746
Number of successful extensions: 3463
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 200
Number of HSP's that attempted gapping in prelim test: 1885
Number of HSP's gapped (non-prelim): 1257
length of query: 355
length of database: 18,247,518
effective HSP length: 103
effective length of query: 252
effective length of database: 14,347,320
effective search space: 3615524640
effective search space used: 3615524640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.