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Search of human proteins with 113722133
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113722133 senataxin [Homo sapiens]
(2677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|113722133 senataxin [Homo sapiens] 5393 0.0
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens] 174 1e-42
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens] 150 1e-35
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 109 3e-23
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 109 3e-23
gi|122937299 DNA replication helicase 2 homolog [Homo sapiens] 102 4e-21
gi|14251207 MOV10-like 1 [Homo sapiens] 102 7e-21
gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap... 92 9e-18
gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi... 92 9e-18
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens] 90 3e-17
gi|38788372 aquarius [Homo sapiens] 84 2e-15
gi|54792138 helicase with zinc finger domain [Homo sapiens] 69 8e-11
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 47 2e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 47 2e-04
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 45 0.001
gi|47578107 delangin isoform B [Homo sapiens] 45 0.001
gi|47578105 delangin isoform A [Homo sapiens] 45 0.001
gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo... 44 0.002
gi|87299628 biorientation of chromosomes in cell division 1-like... 44 0.002
gi|110815815 centlein isoform 1 [Homo sapiens] 44 0.003
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 43 0.005
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 42 0.006
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 42 0.006
gi|104526627 triadin [Homo sapiens] 42 0.006
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 42 0.008
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 42 0.008
gi|55741677 SET domain containing 1A [Homo sapiens] 41 0.014
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 41 0.018
gi|38044112 restin isoform b [Homo sapiens] 41 0.018
gi|4506751 restin isoform a [Homo sapiens] 41 0.018
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 5393 bits (13991), Expect = 0.0
Identities = 2677/2677 (100%), Positives = 2677/2677 (100%)
Query: 1 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 60
MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV
Sbjct: 1 MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEV 60
Query: 61 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 120
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY
Sbjct: 61 LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY 120
Query: 121 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 180
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
Sbjct: 121 PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK 180
Query: 181 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 240
VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG
Sbjct: 181 VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG 240
Query: 241 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 300
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL
Sbjct: 241 ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL 300
Query: 301 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 360
GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
Sbjct: 301 GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN 360
Query: 361 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 420
PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
Sbjct: 361 PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD 420
Query: 421 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 480
LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
Sbjct: 421 LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV 480
Query: 481 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 540
SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR
Sbjct: 481 SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR 540
Query: 541 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 600
SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP
Sbjct: 541 SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP 600
Query: 601 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 660
PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA
Sbjct: 601 PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKA 660
Query: 661 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 720
DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS
Sbjct: 661 DNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS 720
Query: 721 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 780
YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT
Sbjct: 721 YTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT 780
Query: 781 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 840
KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN
Sbjct: 781 KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN 840
Query: 841 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 900
LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT
Sbjct: 841 LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFT 900
Query: 901 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 960
EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR
Sbjct: 901 EMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDR 960
Query: 961 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 1020
DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD
Sbjct: 961 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 1020
Query: 1021 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1080
DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC
Sbjct: 1021 DDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQC 1080
Query: 1081 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1140
FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE
Sbjct: 1081 FEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEE 1140
Query: 1141 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1200
HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS
Sbjct: 1141 HTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKS 1200
Query: 1201 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1260
IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL
Sbjct: 1201 IDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYL 1260
Query: 1261 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1320
SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV
Sbjct: 1261 SCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVV 1320
Query: 1321 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1380
DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT
Sbjct: 1321 DTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHT 1380
Query: 1381 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1440
AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN
Sbjct: 1381 AQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLN 1440
Query: 1441 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1500
QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ
Sbjct: 1441 QCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQ 1500
Query: 1501 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1560
NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN
Sbjct: 1501 NDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKN 1560
Query: 1561 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1620
QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL
Sbjct: 1561 QGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSAL 1620
Query: 1621 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1680
SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK
Sbjct: 1621 SPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESK 1680
Query: 1681 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1740
YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY
Sbjct: 1681 YFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNY 1740
Query: 1741 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1800
GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA
Sbjct: 1741 GDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELA 1800
Query: 1801 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1860
KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS
Sbjct: 1801 KQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLS 1860
Query: 1861 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1920
IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL
Sbjct: 1861 IQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLL 1920
Query: 1921 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1980
TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL
Sbjct: 1921 TTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRL 1980
Query: 1981 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 2040
LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD
Sbjct: 1981 LTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGD 2040
Query: 2041 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2100
INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL
Sbjct: 2041 INLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRAL 2100
Query: 2101 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2160
CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG
Sbjct: 2101 CRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGG 2160
Query: 2161 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2220
LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA
Sbjct: 2161 LLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKA 2220
Query: 2221 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2280
QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN
Sbjct: 2221 QEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN 2280
Query: 2281 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2340
RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR
Sbjct: 2281 RQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFR 2340
Query: 2341 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2400
NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG
Sbjct: 2341 NIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG 2400
Query: 2401 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV 2460
FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV
Sbjct: 2401 FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAV 2460
Query: 2461 KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL 2520
KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL
Sbjct: 2461 KILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITL 2520
Query: 2521 TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV 2580
TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV
Sbjct: 2521 TVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVV 2580
Query: 2581 HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE 2640
HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE
Sbjct: 2581 HQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSE 2640
Query: 2641 GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL 2677
GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL
Sbjct: 2641 GEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL 2677
>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
Length = 1118
Score = 174 bits (440), Expect = 1e-42
Identities = 161/548 (29%), Positives = 251/548 (45%), Gaps = 114/548 (20%)
Query: 1931 LRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHS 1990
L D N Q A++T V P + LI GPPGTGK+ T ++Y L R+G+
Sbjct: 468 LPDLNHSQVYAVKT----VLQRP----LSLIQGPPGTGKTVTSATIVYHLA----RQGNG 515
Query: 1991 DENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPE- 2049
VLVCAPSN AVD+L +KI + + +VRL +
Sbjct: 516 P-----------VLVCAPSNIAVDQLTEKI----------------HQTGLKVVRLCAKS 548
Query: 2050 -KSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQ 2108
++I+S V +L +Q+ + +D + + L
Sbjct: 549 REAIDSPVSFLALHNQIRN-----------------------MDSMPELQKL-------- 577
Query: 2109 RQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFR 2168
Q+L + ++S ++ +K R +++ + +ICCT +G L
Sbjct: 578 -QQLKDETGELSSADEKRYRALKRTAERE------LLMNADVICCTCVGAGDPRLAK--- 627
Query: 2169 GQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQS 2228
+ F +++DE+ Q+ E E + P++ +LILVGD QL P V+ KA + G QS
Sbjct: 628 ----MQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQS 683
Query: 2229 MMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRC 2288
+ R ++ + ++L VQYRMHP + FPSN Y +L+ N T A R
Sbjct: 684 LFERL-----------VVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQ-NGVTAADRV 731
Query: 2289 SSDWPFQ-----PYLVFDVGDGSER--RDNDSYINVQEIKLVMEI-IKLIKDKRKDVSFR 2340
+ FQ + F V G E SY+N E V +I KL+K K
Sbjct: 732 KKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKP---D 788
Query: 2341 NIGIITHYKAQKTMI----QKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQ 2396
IGIIT Y+ Q++ + Q E+ +VDAFQGR+KD +I++CVRAN Q
Sbjct: 789 QIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQ 848
Query: 2397 GSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYR 2456
G IGFL +RLNV +TRA+Y + I+G+ + L + WN L+ +++ +++ N R
Sbjct: 849 G-IGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPLNNLR 907
Query: 2457 HDAVKILK 2464
++ K
Sbjct: 908 ESLMQFSK 915
>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
Length = 993
Score = 150 bits (380), Expect = 1e-35
Identities = 155/604 (25%), Positives = 260/604 (43%), Gaps = 119/604 (19%)
Query: 1954 SVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAV 2013
S ++ +IHGPPGTGK+ T+V ++ + + + + VL CAPSN AV
Sbjct: 205 SQKELAIIHGPPGTGKTTTVVEIILQAVKQGLK----------------VLCCAPSNIAV 248
Query: 2014 DELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKEL 2073
D L++++ L CK + ++RLG + + + SLD+ + ++
Sbjct: 249 DNLVERLAL-----CKQR-----------ILRLGHPARLLESIQQHSLDAVLARSDSAQI 292
Query: 2074 PSHV-----QAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQELAS 2128
+ + Q K K+ D R+++ R ++ R+EL KER+E A
Sbjct: 293 VADIRKDIDQVFVKNKKTQD------KREKSNFRNEIKLLRKEL--------KEREEAA- 337
Query: 2129 KIKEVQGRPQKTQSIIILESHIIC-CTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSC 2187
+LES L+T+ G + + F V++DE Q+
Sbjct: 338 ----------------MLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQAL 381
Query: 2188 EIETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMIS 2247
E PL+ + K IL GD KQLPPT +S KA G S+M R V
Sbjct: 382 EASCWIPLL-KARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARV------ 434
Query: 2248 RLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN--------RQTEAIRCSSDWPFQPYLV 2299
+ LTVQYRMH I + S+ +Y L + R + + + LV
Sbjct: 435 ---VRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLV 491
Query: 2300 FDVGDG---SERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTMIQ 2356
G G E D S N E++LV I+ + D V R+I +++ Y Q +++
Sbjct: 492 DTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVD--AGVPARDIAVVSPYNLQVDLLR 549
Query: 2357 KDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAK 2416
+ L R E+ +VD FQGR+K+ VI++ VR+N +G +GFLA +R+NV +TRA+
Sbjct: 550 QSL---VHRHPELEIKSVDGFQGREKEAVILSFVRSNR-KGEVGFLAEDRRINVAVTRAR 605
Query: 2417 YSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCD-------KNYRHDAVKILKLKPVL 2469
+ ++ RT+ + L++ + G + + +NY H+
Sbjct: 606 RHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHEN---------- 655
Query: 2470 QRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPER 2529
+ +H T +PQG S++ S + A+ K ++ S+ P +
Sbjct: 656 SQGSSHAAT------KPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQ 709
Query: 2530 PPVH 2533
P ++
Sbjct: 710 PSLN 713
>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
[Homo sapiens]
Length = 2649
Score = 109 bits (273), Expect = 3e-23
Identities = 135/530 (25%), Positives = 229/530 (43%), Gaps = 107/530 (20%)
Query: 1960 LIHGPPGTGKSKTIVGL----LYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDE 2015
+I GPPGTGK TIVGL + + Q + ++ +L C PSN +VD
Sbjct: 2171 VIQGPPGTGK--TIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDV 2228
Query: 2016 L----MKKIILE----FKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNH 2067
L ++++ L+ + E+ + + P+ G L+R P + ++ L+ ++H
Sbjct: 2229 LAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLR---SITLHH 2285
Query: 2068 RMKKE---LPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQ 2124
R+++ S ++A R +QR EL R+
Sbjct: 2286 RIRQAPNPYSSEIKAFDTR-----------------------LQRGELFS--------RE 2314
Query: 2125 ELASKIKEVQGRPQKTQSIIILESH-IICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 2183
+L K+V +K + L+ H +I CT S + L+ Q ++VDEA
Sbjct: 2315 DLVW-YKKVLWEARKFE----LDRHEVILCTCSCAASASLKILDVRQ-------ILVDEA 2362
Query: 2184 GQSCEIETLTPLIH--RCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENV 2241
G + E ETL PL+ + K++L+GD KQL P V + + Q G D+S+ R+ E+
Sbjct: 2363 GMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERY----HEDA 2418
Query: 2242 EHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKT---NRQTEAIRCSSDWPFQPYL 2298
L QYRMH IC FPS Y LKT R+ ++ + P +
Sbjct: 2419 H----------MLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCP-V 2467
Query: 2299 VFDVGDGSERR--------DNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKA 2350
+F G ER + +S N++E+ V+ I K + R V ++I ++T Y A
Sbjct: 2468 IFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGR-TVEPQDIAVLTPYNA 2526
Query: 2351 QKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRA------------NSIQGS 2398
Q + I K L +E V ++ QG + V+V+ VR + ++
Sbjct: 2527 QASEISKALRRE--GIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF 2584
Query: 2399 IGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAII 2448
+GF+ ++NV +TRA+ L ++G L W L+ + + ++
Sbjct: 2585 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634
Score = 55.5 bits (132), Expect = 7e-07
Identities = 71/290 (24%), Positives = 126/290 (43%), Gaps = 26/290 (8%)
Query: 2175 FSCVIVDEAGQSCEIETLTPLIHRCN--KLILVGDPKQLPPTVISMKAQEYGYDQSMMAR 2232
FS +++DEA Q E E LTPL + + +L+L GD Q+ P + S+ A+ + +++ R
Sbjct: 661 FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSV-ARARAAEHTLLHR 719
Query: 2233 FCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDW 2292
++ E + ++R L YR I F S + Y + A
Sbjct: 720 LFLCYQQ--ETHEVARQSRLVFHENYRCTDAIVSFISRHFY---VAKGNPIHARGKVPPH 774
Query: 2293 PFQPYLVFDVGDGSERRDND--SYINVQEIKLVMEIIKLIKDKRKDV----SFRNIGIIT 2346
P L+F GS RD S++N+ EI V+E ++ + R I +++
Sbjct: 775 PRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS 834
Query: 2347 HYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-----F 2401
H AQ + ++++L + G V + + GRQ V+++ V S G F
Sbjct: 835 H-GAQVSALRQELRRR--DLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEF 891
Query: 2402 LASLQRLNVTITRAKYSLFILGHLRTLME----NQHWNQLIQDAQKRGAI 2447
+ LN +TRA+ L ++G L + W I++ +R ++
Sbjct: 892 FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSV 941
>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
[Homo sapiens]
Length = 2080
Score = 109 bits (273), Expect = 3e-23
Identities = 135/530 (25%), Positives = 229/530 (43%), Gaps = 107/530 (20%)
Query: 1960 LIHGPPGTGKSKTIVGL----LYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDE 2015
+I GPPGTGK TIVGL + + Q + ++ +L C PSN +VD
Sbjct: 1602 VIQGPPGTGK--TIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDV 1659
Query: 2016 L----MKKIILE----FKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNH 2067
L ++++ L+ + E+ + + P+ G L+R P + ++ L+ ++H
Sbjct: 1660 LAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLR---SITLHH 1716
Query: 2068 RMKKE---LPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQ 2124
R+++ S ++A R +QR EL R+
Sbjct: 1717 RIRQAPNPYSSEIKAFDTR-----------------------LQRGELFS--------RE 1745
Query: 2125 ELASKIKEVQGRPQKTQSIIILESH-IICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 2183
+L K+V +K + L+ H +I CT S + L+ Q ++VDEA
Sbjct: 1746 DLVW-YKKVLWEARKFE----LDRHEVILCTCSCAASASLKILDVRQ-------ILVDEA 1793
Query: 2184 GQSCEIETLTPLIH--RCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENV 2241
G + E ETL PL+ + K++L+GD KQL P V + + Q G D+S+ R+ E+
Sbjct: 1794 GMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERY----HEDA 1849
Query: 2242 EHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKT---NRQTEAIRCSSDWPFQPYL 2298
L QYRMH IC FPS Y LKT R+ ++ + P +
Sbjct: 1850 H----------MLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCP-V 1898
Query: 2299 VFDVGDGSERR--------DNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKA 2350
+F G ER + +S N++E+ V+ I K + R V ++I ++T Y A
Sbjct: 1899 IFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGR-TVEPQDIAVLTPYNA 1957
Query: 2351 QKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRA------------NSIQGS 2398
Q + I K L +E V ++ QG + V+V+ VR + ++
Sbjct: 1958 QASEISKALRRE--GIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF 2015
Query: 2399 IGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAII 2448
+GF+ ++NV +TRA+ L ++G L W L+ + + ++
Sbjct: 2016 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065
Score = 55.5 bits (132), Expect = 7e-07
Identities = 71/290 (24%), Positives = 126/290 (43%), Gaps = 26/290 (8%)
Query: 2175 FSCVIVDEAGQSCEIETLTPLIHRCN--KLILVGDPKQLPPTVISMKAQEYGYDQSMMAR 2232
FS +++DEA Q E E LTPL + + +L+L GD Q+ P + S+ A+ + +++ R
Sbjct: 92 FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSV-ARARAAEHTLLHR 150
Query: 2233 FCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDW 2292
++ E + ++R L YR I F S + Y + A
Sbjct: 151 LFLCYQQ--ETHEVARQSRLVFHENYRCTDAIVSFISRHFY---VAKGNPIHARGKVPPH 205
Query: 2293 PFQPYLVFDVGDGSERRDND--SYINVQEIKLVMEIIKLIKDKRKDV----SFRNIGIIT 2346
P L+F GS RD S++N+ EI V+E ++ + R I +++
Sbjct: 206 PRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS 265
Query: 2347 HYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-----F 2401
H AQ + ++++L + G V + + GRQ V+++ V S G F
Sbjct: 266 H-GAQVSALRQELRRR--DLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEF 322
Query: 2402 LASLQRLNVTITRAKYSLFILGHLRTLME----NQHWNQLIQDAQKRGAI 2447
+ LN +TRA+ L ++G L + W I++ +R ++
Sbjct: 323 FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSV 372
>gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
Length = 1146
Score = 102 bits (255), Expect = 4e-21
Identities = 97/322 (30%), Positives = 147/322 (45%), Gaps = 62/322 (19%)
Query: 2151 ICCTLSTSGGLLLESAFRGQGGVPFSCV---------------IVDEAGQSCEIETLTPL 2195
IC + S LLE + Q V +C+ IVDEA Q + L PL
Sbjct: 803 ICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPL 862
Query: 2196 IHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLT 2255
+ +LVGD +QLPP V++ +A+ G +S+ R LE+N + ++QLT
Sbjct: 863 FFS-RRFVLVGDHQQLPPLVLNREARALGMSESLFKR----LEQN-------KSAVVQLT 910
Query: 2256 VQYRMHPDICLFPSNYVYNRNLKTNRQTEA---------------IRCSSDWPFQPYL-- 2298
VQYRM+ I + Y L+ A + +D+ P+L
Sbjct: 911 VQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMG 970
Query: 2299 VFDVGD-----------GSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITH 2347
VF+ + E+ + NV E KL++ + + + S +IGII
Sbjct: 971 VFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFV--KAGCSPSDIGIIAP 1028
Query: 2348 YKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-FLASLQ 2406
Y+ Q +I L + G EV+TVD +QGR K V+V+ VR+N G++G L +
Sbjct: 1029 YRQQLKIINDLLARSI---GMVEVNTVDKYQGRDKSIVLVSFVRSNK-DGTVGELLKDWR 1084
Query: 2407 RLNVTITRAKYSLFILGHLRTL 2428
RLNV ITRAK+ L +LG + +L
Sbjct: 1085 RLNVAITRAKHKLILLGCVPSL 1106
>gi|14251207 MOV10-like 1 [Homo sapiens]
Length = 1211
Score = 102 bits (253), Expect = 7e-21
Identities = 97/323 (30%), Positives = 151/323 (46%), Gaps = 27/323 (8%)
Query: 2151 ICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPL---IHRCNKLILVGD 2207
I T +S GL + R F+ V VDEAGQ+ E E L PL +++L GD
Sbjct: 859 IIITTCSSSGLFYQIGVRVGH---FTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGD 915
Query: 2208 PKQLPPTVISMKAQEYGYDQS----MMARFCRLLEENVEHNMISRLPIL--QLTVQYRMH 2261
P QL P + S A YG + S +M+R +EN + P+L +L YR H
Sbjct: 916 PMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSH 975
Query: 2262 PDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPY----LVFDVGDGSERRD--NDSYI 2315
+ + PS Y+R L+ + W P L+F GSE R+ + S+
Sbjct: 976 EALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWF 1035
Query: 2316 NVQEIKLVMEIIKLIKDK-RKDVSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTV 2374
N E V+ L+ VS +IG+IT Y+ Q I + L + D +V +V
Sbjct: 1036 NPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKI-RILLRNVDLMD-IKVGSV 1093
Query: 2375 DAFQGRQKDCVIVTCVRANSIQGS-----IGFLASLQRLNVTITRAKYSLFILGHLRTLM 2429
+ FQG++ +I++ VR+N + +GFL++ +R NV ITR K L +LG+ L+
Sbjct: 1094 EEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLV 1153
Query: 2430 ENQHWNQLIQDAQKRGAIIKTCD 2452
+ + L++ + G + CD
Sbjct: 1154 RDPCFGALLEYSITNG-VYMGCD 1175
Score = 38.1 bits (87), Expect = 0.12
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 14/55 (25%)
Query: 1960 LIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVD 2014
++ GPPGTGK+ TI+ + ++ + + +R+LVCAPSN+A D
Sbjct: 767 ILFGPPGTGKTVTIIEAVLQV--------------HFALPDSRILVCAPSNSAAD 807
>gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
Length = 1003
Score = 91.7 bits (226), Expect = 9e-18
Identities = 87/339 (25%), Positives = 152/339 (44%), Gaps = 51/339 (15%)
Query: 2147 ESHIICCTLSTSGGLLLESAFRGQGGVP-FSCVIVDEAGQSCEIETLTPLIHRCN----- 2200
E ++ TL T+G L+ Q + F+ + +DEAG E E+L +
Sbjct: 615 EYRVLITTLITAGRLV-----SAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETG 669
Query: 2201 ----KLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLP------ 2250
+L+L GDP+QL P + S Q++G S++ R LL N ++ + P
Sbjct: 670 DPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLER---LLTYN---SLYKKGPDGYDPQ 723
Query: 2251 -ILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDV------G 2303
I +L YR HP I P+ Y L+ W P F + G
Sbjct: 724 FITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMG 783
Query: 2304 DGSERRDNDSYINVQEIKLVMEIIKLI-----KDKRKDVSFRNIGIITHYKAQKTMIQ-- 2356
++ S+ N +E V +KL+ K + +S R++G+I+ Y+ Q I+
Sbjct: 784 KDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYC 843
Query: 2357 -KDLDKEF---DRKGPAEVDTVDAFQGRQKDCVIVTCVRANS------IQGSIGFLASLQ 2406
LD+E D +V +V+ FQG+++ ++++ VR++ + ++GFL + +
Sbjct: 844 ITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPK 903
Query: 2407 RLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRG 2445
R NV +TRAK L I+G+ L + W ++ ++ G
Sbjct: 904 RFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENG 942
Score = 35.8 bits (81), Expect = 0.58
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 14/61 (22%)
Query: 1960 LIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKK 2019
+I GPPGTGK+ T+V + + + ++ K H +L CAPSN+ D L ++
Sbjct: 521 IIFGPPGTGKTVTLVEAI-KQVVKHLPKAH-------------ILACAPSNSGADLLCQR 566
Query: 2020 I 2020
+
Sbjct: 567 L 567
>gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
Length = 1003
Score = 91.7 bits (226), Expect = 9e-18
Identities = 87/339 (25%), Positives = 152/339 (44%), Gaps = 51/339 (15%)
Query: 2147 ESHIICCTLSTSGGLLLESAFRGQGGVP-FSCVIVDEAGQSCEIETLTPLIHRCN----- 2200
E ++ TL T+G L+ Q + F+ + +DEAG E E+L +
Sbjct: 615 EYRVLITTLITAGRLV-----SAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETG 669
Query: 2201 ----KLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLP------ 2250
+L+L GDP+QL P + S Q++G S++ R LL N ++ + P
Sbjct: 670 DPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLER---LLTYN---SLYKKGPDGYDPQ 723
Query: 2251 -ILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDV------G 2303
I +L YR HP I P+ Y L+ W P F + G
Sbjct: 724 FITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMG 783
Query: 2304 DGSERRDNDSYINVQEIKLVMEIIKLI-----KDKRKDVSFRNIGIITHYKAQKTMIQ-- 2356
++ S+ N +E V +KL+ K + +S R++G+I+ Y+ Q I+
Sbjct: 784 KDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYC 843
Query: 2357 -KDLDKEF---DRKGPAEVDTVDAFQGRQKDCVIVTCVRANS------IQGSIGFLASLQ 2406
LD+E D +V +V+ FQG+++ ++++ VR++ + ++GFL + +
Sbjct: 844 ITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPK 903
Query: 2407 RLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRG 2445
R NV +TRAK L I+G+ L + W ++ ++ G
Sbjct: 904 RFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENG 942
Score = 35.8 bits (81), Expect = 0.58
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 14/61 (22%)
Query: 1960 LIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKK 2019
+I GPPGTGK+ T+V + + + ++ K H +L CAPSN+ D L ++
Sbjct: 521 IIFGPPGTGKTVTLVEAI-KQVVKHLPKAH-------------ILACAPSNSGADLLCQR 566
Query: 2020 I 2020
+
Sbjct: 567 L 567
>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
Length = 1918
Score = 89.7 bits (221), Expect = 3e-17
Identities = 77/285 (27%), Positives = 141/285 (49%), Gaps = 27/285 (9%)
Query: 2178 VIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTV-ISMKAQEYGYDQSMMARFCRL 2236
VIV+EA + E T+ L C LIL+GD +QL P+ + A+ + + S+ F RL
Sbjct: 1003 VIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSL---FERL 1059
Query: 2237 LEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYN--RNLKTNRQTEAIRCSSDWPF 2294
++ N+ P ++L Q+RM P+I + ++Y N + + E I+ S
Sbjct: 1060 VKVNI--------PFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSS--- 1108
Query: 2295 QPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTM 2354
+ V E ++ S+ N E V+E+ K + S I I+T Y Q
Sbjct: 1109 NLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPS--QITILTTYTGQLFC 1166
Query: 2355 IQKDLD-KEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTIT 2413
++K + K F V VD +QG + D ++++ VR+N +G +GFL R+ V ++
Sbjct: 1167 LRKLMPAKTF---AGVRVHVVDKYQGEENDIILLSLVRSNQ-EGKVGFLQISNRICVALS 1222
Query: 2414 RAKYSLFILGHLRTLMENQHWNQLIQDAQKR---GAIIKTCDKNY 2455
RAK ++ +G+++ L + W+++I ++ G +++ C +N+
Sbjct: 1223 RAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQIGPMLRLCCQNH 1267
Score = 42.7 bits (99), Expect = 0.005
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 31/154 (20%)
Query: 1957 KICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDEL 2016
++ +I GPPGTGK+ + ++ LLT ++ +++ +LV +N A+D+
Sbjct: 613 ELAIIQGPPGTGKTYVGLKIVQALLT-------NESVWQISLQKFPILVVCYTNHALDQF 665
Query: 2017 MKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLK-FSLDSQVNHR-MKKELP 2074
++ I NC ++VR+G NSE+LK F+L N R ++ LP
Sbjct: 666 LEGIY---------------NCQKTSIVRVGGRS--NSEILKQFTLRELRNKREFRRNLP 708
Query: 2075 SHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQ 2108
MH R+ ++ ++ L G + ++
Sbjct: 709 -----MHLRRAYMSIMTQMKESEQELHEGAKTLE 737
>gi|38788372 aquarius [Homo sapiens]
Length = 1485
Score = 84.0 bits (206), Expect = 2e-15
Identities = 119/563 (21%), Positives = 231/563 (41%), Gaps = 107/563 (19%)
Query: 1934 FNEDQKKAIETAYAMVK--HSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSD 1991
+N+ ++ I+ + ++ + + ++ GPPGTGK+ V ++
Sbjct: 792 YNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQII-------------- 837
Query: 1992 ENSNAKIKQNRVLVCAPSNAAVDELMKKII-----------LEFKEKCKDKKNPLGNCGD 2040
N + R L+ SN A+++L +KI+ L E+ + + G
Sbjct: 838 SNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGR 897
Query: 2041 INLV----------------RLGP--EKSINSEVLKFSLDSQVNHRMK------KELPSH 2076
+N V LG + S E + QV R + K S
Sbjct: 898 VNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGST 957
Query: 2077 VQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDE----NISKVSKERQELASKIKE 2132
+ + + F + + + + +G + E+ E +I K+ + +E + +
Sbjct: 958 LPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRAS-EL 1016
Query: 2133 VQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETL 2192
++ +++ +++ E+ II T + + L+ + G + ++++EA Q EIET
Sbjct: 1017 LRSGLDRSKYLLVKEAKIIAMTCTHAA---LKRHDLVKLGFKYDNILMEEAAQILEIETF 1073
Query: 2193 TPLI--------HRCNKLILVGDPKQLPPTVISMKAQEYG-YDQSMMARFCRLLEENVEH 2243
PL+ R + I++GD QLPP + +M Q+Y +QS+ RF R+
Sbjct: 1074 IPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRV------- 1126
Query: 2244 NMISRLPILQLTVQYRMHPDIC-LFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDV 2302
+P + L Q R +C L+ Y NL + ++ + + +V
Sbjct: 1127 ----GVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINV 1182
Query: 2303 GD----GSERRDNDSYINVQEIKLVMEIIKLI------KDKRKDVSFRNIGIITHYKAQK 2352
D G + Y N+ E + V+ + + DK I I+T Y QK
Sbjct: 1183 EDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADK--------ISILTTYNGQK 1234
Query: 2353 TMIQKDLDKEFDRKG----PAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRL 2408
+I+ +++ P +V TVD FQG+Q D ++++ VR ++G L ++RL
Sbjct: 1235 HLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTR----AVGHLRDVRRL 1290
Query: 2409 NVTITRAKYSLFILGHLRTLMEN 2431
V ++RA+ L+I + +L +N
Sbjct: 1291 VVAMSRARLGLYIFARV-SLFQN 1312
>gi|54792138 helicase with zinc finger domain [Homo sapiens]
Length = 1942
Score = 68.6 bits (166), Expect = 8e-11
Identities = 81/319 (25%), Positives = 137/319 (42%), Gaps = 57/319 (17%)
Query: 2138 QKTQSIIILESHIICCTLSTSGGLL---LESAFRGQGGVPFSCVIVDEAGQSCEIETLTP 2194
Q Q IL+ ++ TL+TS L LE F F+ +++DEA Q+ E ET+ P
Sbjct: 755 QMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGF-------FTHILLDEAAQAMECETIMP 807
Query: 2195 --LIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPIL 2252
L + +++L GD QL P V S A+E S LL+ EH +
Sbjct: 808 LALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVS-------LLDRLYEHYPAEFPCRI 860
Query: 2253 QLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDV-GDGSERRDN 2311
L YR H I + S Y L + + A + F P F G+ + +++
Sbjct: 861 LLCENYRSHEAIINYTSELFYEGKLMASGKQPAHK-----DFYPLTFFTARGEDVQEKNS 915
Query: 2312 DSYINVQEIKLVMEIIKLIKDKRK-------DVSFRNIGIITHYKAQKTMIQKDLDKEFD 2364
++ N E V E+++ +++ R+ + +IG++T Y Q I+ +L K+
Sbjct: 916 TAFYNNAE---VFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKK-- 970
Query: 2365 RKGPAEVDTVDAFQGRQKDCVIVTCVRA--------------------NSIQGSIGFLAS 2404
R V+ V QG+Q + ++ VR ++ GFL++
Sbjct: 971 RLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSN 1030
Query: 2405 LQRLNVTITRAKYSLFILG 2423
+ LN ITRA+ + ++G
Sbjct: 1031 YKLLNTAITRAQSLVAVVG 1049
Score = 33.5 bits (75), Expect = 2.9
Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 15/76 (19%)
Query: 1960 LIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKK 2019
LI GP GTGK+ T+ + +L + ++ R+L+C SN+A D +K
Sbjct: 665 LIIGPYGTGKTFTLAQAVKHILQQ---------------QETRILICTHSNSAADLYIKD 709
Query: 2020 IILEFKEKCKDKKNPL 2035
+ + E + PL
Sbjct: 710 YLHPYVEAGNPQARPL 725
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 47.4 bits (111), Expect = 2e-04
Identities = 111/601 (18%), Positives = 207/601 (34%), Gaps = 108/601 (17%)
Query: 618 SYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADNTIEGDNNEQNYIKDV 677
S+ E ++ +T K H +K KVQD + A+ ++ D +++ D
Sbjct: 892 SFTSLEVRKVAETKEKSKHLK-------TKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK 944
Query: 678 KLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISSYTPKDCTSRNGPERGCD 737
K QS K E++ K S K+K +K Y + PER
Sbjct: 945 K------------QSKKG-----TEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEI 987
Query: 738 RGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT----KVQKDEICAKLSH 793
+ + + +TD +K + S K D L+ +++ T E +
Sbjct: 988 CHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG 1047
Query: 794 VIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPSGVLDDKN 853
++ ++ L+ + ++ + S+ E YS K+ G D + + L L K
Sbjct: 1048 AYGREKKRCKLLGKSSRKRQDCSSSDTEK-YSMKEDGCNSSDKRLKRIELRERRNLSSKR 1106
Query: 854 GEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFTEMTNASEKKSSPF 913
++ Q+ + + +E+ ++++S
Sbjct: 1107 NTKEIQSGSSSSDAEESSED-----------------------------NKKKKQRTSSK 1137
Query: 914 KDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRDLHKLSLLAQASV 973
K + V E + + ST R+QA S S + D Q S+
Sbjct: 1138 KKAVIVKEKKRNSLRTSTK-------RKQADITSSSSSDIEDDD------------QNSI 1178
Query: 974 ITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKL 1033
SD + + V F + + + V + D DD+D E ++ + L
Sbjct: 1179 GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKML 1238
Query: 1034 TKQDKICLEREH-------PEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQCFEFESS 1086
++ K L + PE+ + E+NP EE + +SDS E
Sbjct: 1239 LEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDS---EESKK 1295
Query: 1087 SEVFSVWQDHPDDNNSVQDGEKKCLAPIAN-----------TTNGQGCTDYVSEVVKKGA 1135
H + + GE+K P + ++ +D+ V +
Sbjct: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1355
Query: 1136 EGIEEHTRPRSISVEEFCEIEVK----KPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKR 1191
E+ RPR+ S ++ E+E K K+KR + ED SS N+ S+ +
Sbjct: 1356 SESEDEQRPRTRSAKK-AELEENQRSYKQKKKRRRIKVQED-----SSSENKSNSEEEEE 1409
Query: 1192 D 1192
+
Sbjct: 1410 E 1410
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 47.4 bits (111), Expect = 2e-04
Identities = 111/601 (18%), Positives = 207/601 (34%), Gaps = 108/601 (17%)
Query: 618 SYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADNTIEGDNNEQNYIKDV 677
S+ E ++ +T K H +K KVQD + A+ ++ D +++ D
Sbjct: 930 SFTSLEVRKVAETKEKSKHLK-------TKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK 982
Query: 678 KLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISSYTPKDCTSRNGPERGCD 737
K QS K E++ K S K+K +K Y + PER
Sbjct: 983 K------------QSKKG-----TEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEI 1025
Query: 738 RGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT----KVQKDEICAKLSH 793
+ + + +TD +K + S K D L+ +++ T E +
Sbjct: 1026 CHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG 1085
Query: 794 VIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPSGVLDDKN 853
++ ++ L+ + ++ + S+ E YS K+ G D + + L L K
Sbjct: 1086 AYGREKKRCKLLGKSSRKRQDCSSSDTEK-YSMKEDGCNSSDKRLKRIELRERRNLSSKR 1144
Query: 854 GEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFTEMTNASEKKSSPF 913
++ Q+ + + +E+ ++++S
Sbjct: 1145 NTKEIQSGSSSSDAEESSED-----------------------------NKKKKQRTSSK 1175
Query: 914 KDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRDLHKLSLLAQASV 973
K + V E + + ST R+QA S S + D Q S+
Sbjct: 1176 KKAVIVKEKKRNSLRTSTK-------RKQADITSSSSSDIEDDD------------QNSI 1216
Query: 974 ITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKL 1033
SD + + V F + + + V + D DD+D E ++ + L
Sbjct: 1217 GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKML 1276
Query: 1034 TKQDKICLEREH-------PEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQCFEFESS 1086
++ K L + PE+ + E+NP EE + +SDS E
Sbjct: 1277 LEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDS---EESKK 1333
Query: 1087 SEVFSVWQDHPDDNNSVQDGEKKCLAPIAN-----------TTNGQGCTDYVSEVVKKGA 1135
H + + GE+K P + ++ +D+ V +
Sbjct: 1334 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1393
Query: 1136 EGIEEHTRPRSISVEEFCEIEVK----KPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKR 1191
E+ RPR+ S ++ E+E K K+KR + ED SS N+ S+ +
Sbjct: 1394 SESEDEQRPRTRSAKK-AELEENQRSYKQKKKRRRIKVQED-----SSSENKSNSEEEEE 1447
Query: 1192 D 1192
+
Sbjct: 1448 E 1448
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 44.7 bits (104), Expect = 0.001
Identities = 131/640 (20%), Positives = 234/640 (36%), Gaps = 108/640 (16%)
Query: 621 KEESEQMGKTSRKDMHCLEASSPTFSKEPMK--VQDSVLIKADNTIEGDNNEQNYIKDVK 678
K E + M +R + LE ++ KE K V+ V++K + + +N E+ IK+
Sbjct: 254 KSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLP-ENEEKKIIKE-- 310
Query: 679 LEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISSYTPKDCTSRNGPERGCDR 738
K++ K I E E + K K ++ PER
Sbjct: 311 ------ESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQE----------PERIEFG 354
Query: 739 GIIVSTRLLTDSSTDALEKVSTSNE--------DFSLKDD-------ALAKTSKRKTKVQ 783
G I S+ +T+ ST+ EK+ + + L DD L K+ +
Sbjct: 355 GNIKSSHEITEKSTEETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTPTKEFL 414
Query: 784 KDEI------CAKLSHVIKKQHRKSTLVDNTIN---LDENLTVSNIES-FYSRKDTGVQK 833
KDEI C ++S + H LV+ ++ + N IE+ FY K+
Sbjct: 415 KDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEE---- 470
Query: 834 GDGFIHNLSLDPS---GVLDDKNGEQKSQNNVLPKEK--QLKNEELVIFSFHENNCKIQE 888
S PS ++ + NG + S N+V+ K +L+ E + +++ + E
Sbjct: 471 --------SYSPSKDRNIITEGNGTE-SLNSVITSMKTGELEKETAPLRKDADSSISVLE 521
Query: 889 FHVDGKELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISP 948
H ++ E+ P + +++S+ T++ + + + SP
Sbjct: 522 IHSQKAQI----------EEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSP 571
Query: 949 KSDTLTDSQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDT 1008
K+ I L KL + S TF Q S + +V + T G
Sbjct: 572 KTKKDKRPPILECLEKL----EKSKKTFLDKDAQRLSPIPEEVPKS----TLESEKPGSP 623
Query: 1009 SRGQVIIISDSDDDDDERILSLEKLTKQDKICLEREHPE-QHVSTVNSKEEKNPVKEEKT 1067
+ S+ D +K+ E+E E Q STV + VK+
Sbjct: 624 EAAETSPPSNIID-------------HCEKLASEKEVVECQSTSTVGGQS----VKKVDL 666
Query: 1068 ETLFQFEESDSQCFEFESSSEVFSVWQDHPDD-NNSVQDGE-KKCLAPIANTTNGQGCTD 1125
ETL E+S+ E ++ + + P + S+Q + K L P TT + T+
Sbjct: 667 ETL--KEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASEN-TE 723
Query: 1126 YVSEVVKKGAEGIEEHTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQ 1185
SE K EGI+ R S + +V +P+ K+ + E+ ++R +
Sbjct: 724 ITSERQK---EGIKLTIRISSRKKKPDSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPR 780
Query: 1186 SDTNKRDLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSK 1225
+ + D++ ++ +T QK K
Sbjct: 781 ISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKK 820
Score = 37.4 bits (85), Expect = 0.20
Identities = 125/628 (19%), Positives = 231/628 (36%), Gaps = 99/628 (15%)
Query: 996 RCFTANQNNVGDTS---RGQV--IIISDSDDDDDERILSLEKLTKQDKICLEREHPEQHV 1050
+C N+N + +T + Q+ +++ +S D+ + ++ LE E +
Sbjct: 189 KCIVRNRNELAETLALLKAQIDPVLLKNSSQQDN---------SSRESPSLEDEETK--- 236
Query: 1051 STVNSKEEKNPVKEEKTETLFQFEESDSQCFEFESSSEVFSVWQDHPDDNNSVQDGEKKC 1110
KEE+ P +EE+ E+ E E S++ V + +D ++
Sbjct: 237 -----KEEETPKQEEQKESEKMKSEEQPMDLENRSTANVL----EETTVKKEKEDEKELV 287
Query: 1111 LAPIANTTNGQGCTDYVSEVVKKGAEGIEEHTRPRSISVEEFCEIEVKKPKRKRSEKPMA 1170
P+ + +++K+ ++ +E+ +P + V+E C + K K EKP+A
Sbjct: 288 KLPVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVKE-CRADPKDTK-SSMEKPVA 345
Query: 1171 EDPVRPSSSVRNEGQSDTNKRDLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCT 1230
++P R + + + KS + N Q+A +K+ KL
Sbjct: 346 QEPERIEFGGNIKSSHEITE--------KSTEETEKLKND--QQAKIPLKKREIKLSDDF 395
Query: 1231 EPIRKVPVSK--TPKKTH-SDAKKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKL 1287
+ K P+ K TP K D K + + +S T A+ K E +
Sbjct: 396 DSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRIS--TITALGHEGKQLVNGEVSDERVAP 453
Query: 1288 GLKKGP--RKAYELSQRSLDYVAQLRDHGKTVGVVDTRKKTKLISPQNLSVRNNKKLLTS 1345
K P K YE + S K +I+ N + N + +
Sbjct: 454 NFKTEPIETKFYETKEES----------------YSPSKDRNIITEGNGTESLNSVITSM 497
Query: 1346 QELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHTAQNSDIFVPESDRSDYNCTGGTEVL 1405
+ +++++ P R+ +D S V S AQ + PE + S +E+
Sbjct: 498 KTGELEKETAP-----LRKDAD-SSISVLEIHSQKAQIEEPDPPEMETS----LDSSEMA 547
Query: 1406 ANSNRKQLIKCMPSEPETIKAKHGSPAT--DDACPLNQCDSVVLNGTVPTNEVIVSTSED 1463
+ + K + +E T+K + SP T D P+ +C L + + +
Sbjct: 548 KDLSSKTALS--STESCTMKGEEKSPKTKKDKRPPILEC----LEKLEKSKKTFLDKDAQ 601
Query: 1464 PLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQNDPEDMDLCSQMENDNYKLIELI 1523
L P + + L+ +P S AE T +D C ++ ++ E++
Sbjct: 602 RL---SPIPEEVPKSTLESEKPGSPEAAE------TSPPSNIIDHCEKLASEK----EVV 648
Query: 1524 HGKDTVEVEEDSVSRPQLESLSG----TKCKYKDCLETTKNQGEYCPKHSEVKAADEDVF 1579
+ T V SV + LE+L TK + D L+ + G P SE K + +
Sbjct: 649 ECQSTSTVGGQSVKKVDLETLKEDSEFTKVE-MDNLDNAQTSGIEEP--SETKGSMQKSK 705
Query: 1580 RKPGLPPPASKPLRPTTKIFSSKSTSRI 1607
K L P T+I S + I
Sbjct: 706 FKYKLVPEEETTASENTEITSERQKEGI 733
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 44.7 bits (104), Expect = 0.001
Identities = 67/355 (18%), Positives = 143/355 (40%), Gaps = 42/355 (11%)
Query: 961 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 1020
DLH+ + + IT SDS +K +E K+C A + + + G + ++
Sbjct: 544 DLHQAGRVDSQASITQDSDSI-------KKPEEIKQCNDAPVSVLQEDIVGSLKSTPENH 596
Query: 1021 DD-----DDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEE 1075
+ D + E + ++ + + + V T +S+ + E +TE L Q E
Sbjct: 597 PETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNES 656
Query: 1076 SDSQCFEFESS----SEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVV 1131
++C + ES+ + + D ++N +G + T +G + E
Sbjct: 657 RTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKG--ESRPETP 714
Query: 1132 KKGAEGIEEHTRP----RSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSD 1187
K+ ++G E + R + ++ E + PK+K +P E P + R+ G+
Sbjct: 715 KQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRP--ETPKHRHDNRRDSGKPS 772
Query: 1188 TNKRDLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHS 1247
T K+ V + D ++ +P + +RA + Q+ + VS++ ++ H
Sbjct: 773 TEKKPEVSKHKQ--DTKSDSPRLKSERAEALKQRPDGR-----------SVSESLRRDHD 819
Query: 1248 DAKKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQR 1302
+ +K +R + + P+ R +S+ + G+K K +L ++
Sbjct: 820 NKQKSDDRGESERHRGDQSRVRRPETLR-----SSSRNEHGIKSDSSKTDKLERK 869
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 44.7 bits (104), Expect = 0.001
Identities = 67/355 (18%), Positives = 143/355 (40%), Gaps = 42/355 (11%)
Query: 961 DLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSD 1020
DLH+ + + IT SDS +K +E K+C A + + + G + ++
Sbjct: 544 DLHQAGRVDSQASITQDSDSI-------KKPEEIKQCNDAPVSVLQEDIVGSLKSTPENH 596
Query: 1021 DD-----DDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEE 1075
+ D + E + ++ + + + V T +S+ + E +TE L Q E
Sbjct: 597 PETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNES 656
Query: 1076 SDSQCFEFESS----SEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVV 1131
++C + ES+ + + D ++N +G + T +G + E
Sbjct: 657 RTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKG--ESRPETP 714
Query: 1132 KKGAEGIEEHTRP----RSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSD 1187
K+ ++G E + R + ++ E + PK+K +P E P + R+ G+
Sbjct: 715 KQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRP--ETPKHRHDNRRDSGKPS 772
Query: 1188 TNKRDLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHS 1247
T K+ V + D ++ +P + +RA + Q+ + VS++ ++ H
Sbjct: 773 TEKKPEVSKHKQ--DTKSDSPRLKSERAEALKQRPDGR-----------SVSESLRRDHD 819
Query: 1248 DAKKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQR 1302
+ +K +R + + P+ R +S+ + G+K K +L ++
Sbjct: 820 NKQKSDDRGESERHRGDQSRVRRPETLR-----SSSRNEHGIKSDSSKTDKLERK 869
>gi|155969714 nuclear protein, ataxia-telangiectasia locus [Homo
sapiens]
Length = 1427
Score = 44.3 bits (103), Expect = 0.002
Identities = 58/246 (23%), Positives = 98/246 (39%), Gaps = 23/246 (9%)
Query: 755 LEKVSTSNEDFSLKDDALAKTSKRKTKVQKDEICAKLSHVIKKQHRKSTLVDNTINLDEN 814
L K+ + +E + + +T K KV EI V++ H+ + +N + D
Sbjct: 1124 LPKILSKSESAISRHTTIRETQSEK-KVSPTEI------VLESFHKATANKENELCSDVE 1176
Query: 815 LTVSNIESFYSRKDTGVQKGDGFIHNLSLDPSGVLDDKNGEQKSQNNVLP---KEKQLKN 871
N E+ S+ G Q G G S+ + K G + NVL K LK
Sbjct: 1177 RQ-KNPEN--SKLSIGQQNG-GLRSEKSIASLQEMTKKQGTSSNNKNVLSVGTAVKDLKQ 1232
Query: 872 EELVIFSFHENNCKIQEFH--------VDGKEL-IPFTEMTNASEKKSSPFKDLMTVPES 922
E+ S +Q+ D +L +P T + A EK D++ P S
Sbjct: 1233 EQTKSASSLITTEMLQDIQRHSSVSRLADSSDLPVPRTPGSGAGEKHKEEPIDIIKAPSS 1292
Query: 923 RDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRDLHKLSLLAQASVITFPSDSPQ 982
R +STS + P SP S+T +++ ++ H L +L++A++ S +P
Sbjct: 1293 RRFSEDSSTSKVMVPPVTPDLPACSPASETGSENSVNMAAHTLMILSRAAISRTTSATPL 1352
Query: 983 NSSQLQ 988
+ Q
Sbjct: 1353 KDNTQQ 1358
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 43.9 bits (102), Expect = 0.002
Identities = 99/483 (20%), Positives = 181/483 (37%), Gaps = 83/483 (17%)
Query: 900 TEMTNA--SEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTRE---QAPDISPKSDTLT 954
TE +NA SE+ S T S D+E ++ T + + + +PKS+ +
Sbjct: 222 TETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFS 281
Query: 955 DSQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVI 1014
D + K ++I D Q SS+ + K T +G+
Sbjct: 282 DLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNK----------------STDKGE-- 323
Query: 1015 IISDSDDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFE 1074
D +E+ K K++K + +H ++ T K+EK ++E E
Sbjct: 324 ----KKPDSNEK--GERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSE 377
Query: 1075 ESDSQCFEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDY-VSEVVKK 1133
++ ++ E + E FS+ D G TD VS V
Sbjct: 378 KNSNKAKTVEGTKEDFSLIDSDVD-----------------------GLTDITVSSVHTS 414
Query: 1134 GAEGIEEHTRPRSISVEEFCEIEV-----KKPKRKRSEKPMAEDPVRPSSSVRNEGQSDT 1188
EE T ++ + E E+ +K K+ +++ ++ + SVR+ +
Sbjct: 415 DLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRH---AYV 471
Query: 1189 NKRDLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPK--KTH 1246
+K L + D + QR +++++K +L K+ + K KT
Sbjct: 472 HKPYLYSKYYSDSDDELTVE----QRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTK 527
Query: 1247 SDAKKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDY 1306
S KGQ RSS L +T ++ P+ E L +K K LS++
Sbjct: 528 SSKTKGQGRSSVDLEESSTKSLE--------PKAARIKEVLKERKVLEKKVALSKKRKKD 579
Query: 1307 VAQLRDHGKTVGVVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQ--KNRRR 1364
+ ++ K + K L + ++ +K+ +S+EL + + KS+ K RR
Sbjct: 580 SRNVEENSKKKQQYEEDSKETLKTSEHC---EKEKISSSKEL---KHVHAKSEPSKPARR 633
Query: 1365 LSD 1367
LS+
Sbjct: 634 LSE 636
Score = 40.4 bits (93), Expect = 0.024
Identities = 133/714 (18%), Positives = 262/714 (36%), Gaps = 97/714 (13%)
Query: 642 SPTFSKEPMKVQDSVLIKADNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERA 701
S FS P V++ N + NN KDV+ E + K +
Sbjct: 277 SEEFSDLPCPVEE-----IKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEK 331
Query: 702 EDQIKISTRKQKSVKEISSYTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTS 761
++ K +K+K+ K+ + T + E+ + S +L ++ +++ + V +
Sbjct: 332 GERKK--EKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGT 389
Query: 762 NEDFSLKD-DALAKTSKRKTKVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNI 820
EDFSL D D T + V ++ + ++ ++ + I D+
Sbjct: 390 KEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQN 449
Query: 821 ESFYSRKDTGVQKGDGFIHNLSLDP-------SGVLDDKNGEQKSQNNVLPKEKQLKNEE 873
++ D+ K H P S D+ EQ+ Q+ KE++L +
Sbjct: 450 KTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQ 509
Query: 874 LVIFSFHE------NNCKIQEFHVDGKELIPFTE-MTNASEKKSSPFKDLMTVPESRDEE 926
+ E K + G+ + E T + E K++ K+++ + +++
Sbjct: 510 INREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKK 569
Query: 927 MSNS------TSVIYSNLTREQAPDISPKSDTLTDSQIDRD-LHKLSLLAQASVITFPSD 979
++ S + + N ++Q + K T +++ + L + PS
Sbjct: 570 VALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSK 629
Query: 980 SPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKLTKQDKI 1039
+ S+ V E+K + + TS +I+ ++ D R +++ ++ +I
Sbjct: 630 PARRLSESLHVVDENKNESKLEREHKRRTS--TPVIMEGVQEETDTR--DVKRQVERSEI 685
Query: 1040 CLEREHPEQHVSTVNSKEEKNPVKEE-KTETLFQFEESDSQCFEFESSSEVFSVWQDHPD 1098
C E P++ ST+ K EK+ K++ +T L + E +SS E + +
Sbjct: 686 C--TEEPQKQKSTL--KNEKHLKKDDSETPHLKSLLKK-----EVKSSKEKPEREKTPSE 736
Query: 1099 DNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEEHTRPRSISVEEFCEIEVK 1158
D SV+ Y + + K + E H+ + + VEE +
Sbjct: 737 DKLSVKH-------------------KYKGDCMHKTGDETELHSSEKGLKVEENIQ---- 773
Query: 1159 KPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKSIDRRTSTPNSRIQRATTV 1218
K+ + K ++D S RNE K ++G D K + + +++
Sbjct: 774 --KQSQQTKLSSDDKTERKSKHRNE-----RKLSVLGKDGKPVSEYIIKTDENVRKENNK 826
Query: 1219 SQKKSSKLCTCTE-PIRKVPVSKTPKKTHSDAKKG---QNRSSNYLSCRTTPAIVPPKKF 1274
+++ S T E R+ SK K + + G Q RS +Y +
Sbjct: 827 KERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKC---------- 876
Query: 1275 RQCPEPTSTAEKLGLK------KGPRKAYELSQRSLDYVAQLRDHGKTVGVVDT 1322
+ ST LK K R+ L + L ++ + GK V VV+T
Sbjct: 877 ----DMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVET 926
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 43.5 bits (101), Expect = 0.003
Identities = 94/466 (20%), Positives = 163/466 (34%), Gaps = 77/466 (16%)
Query: 628 GKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADNTIEGDNNEQNYIKDVKLEDHLLAGS 687
GKT + H A PTF K+ K+Q S + + + + LL
Sbjct: 928 GKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTAVPTRVNREKYKNITAQKSSSNIILLRER 987
Query: 688 CLKQSSKNIFTERAEDQIKISTRKQKSVKEISSYTPKDCTSRNGPERGCDRGIIVSTRLL 747
+ +N + A+ ++S ++ K V E + + R R + + + L
Sbjct: 988 IISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGL 1047
Query: 748 TDSSTDALEKVSTSNEDFSLKDDALAKTSKR----------------------------- 778
D L+K+ +S+E SL ++ T R
Sbjct: 1048 RKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKLKNATNE 1107
Query: 779 ------KTKVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQ 832
K K E+ AK H IK+ H K + ++ I + +L IE R+ ++
Sbjct: 1108 LTKQSSNVKTLKFELLAKEEH-IKEMHEKISRMERDITMKRHL----IEDLKFRQKVNLE 1162
Query: 833 KGDGFIHNLSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVD 892
F L Q V ++ N+++ I S Q +V
Sbjct: 1163 SNKSFSEML--------------QNLDKKVKTLTEECSNKKVSIDSLK------QRLNVA 1202
Query: 893 GKELIPFTEMTNASEKKSSPFKDL-MTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSD 951
KE + +M S K+ KDL +T+ SR E ++ + I E A +
Sbjct: 1203 VKEKSQYEQMYQKS-KEELEKKDLKLTLLVSRISETESAMAEI------ETAASKQLQEL 1255
Query: 952 TLTDSQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQ-------RKVKEDKRCFTANQNN 1004
L Q+ K LLA V F + + +LQ R+++E K+
Sbjct: 1256 ALQSEQVLEGAQKTLLLANEKVEEFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDAC 1315
Query: 1005 VGDTSRGQVIIIS--DSDDDDDERILSLEKLTKQDKICLEREHPEQ 1048
T + Q + S + D E IL E + +K ++ E+ ++
Sbjct: 1316 KTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAENDKE 1361
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 42.7 bits (99), Expect = 0.005
Identities = 49/226 (21%), Positives = 87/226 (38%), Gaps = 37/226 (16%)
Query: 1026 RILSLEK-LTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQCFEFE 1084
++ S EK + K+DK P V SKEE +PVK E E +++ +
Sbjct: 579 KVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAE-----KQATDVKPKAA 633
Query: 1085 SSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEEHTRP 1144
V + P+D ++ KK +A K+ I++ +P
Sbjct: 634 KEKTVKKETKVKPEDKKEEKEKPKKEVAK------------------KEDKTPIKKEEKP 675
Query: 1145 RSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKSIDRR 1204
+ V++ + E+KK ++K P V+ E K+++ + K + +
Sbjct: 676 KKEEVKKEVKKEIKKEEKK-----------EPKKEVKKETPPKEVKKEVKKEEKKEVKKE 724
Query: 1205 TSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAK 1250
P I++ ++K S+ L +P P K PKK S K
Sbjct: 725 EKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKP--KVPKKEESVKK 768
Score = 39.3 bits (90), Expect = 0.053
Identities = 52/270 (19%), Positives = 113/270 (41%), Gaps = 38/270 (14%)
Query: 1128 SEVVKKGAEGIE-EHTRPRSISVEEFCEIEVKKPKRKRSEKPMAED----PVRPSSSVRN 1182
+EV +K A ++ + + +++ E + E KK ++++ +K +A+ P++ +
Sbjct: 618 AEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKK 677
Query: 1183 EGQSDTNKRDLVGNDFKSIDR--RTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSK 1240
E K+++ + K + + TP +++ +KK K K
Sbjct: 678 EEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVK-----------KEEK 726
Query: 1241 TPKKTHSDAKKGQNRSSNYLSCRTTPAIVPPK--KFRQCPEPTSTAEKLGLKKGPRKAYE 1298
PKK K +SS LS PA + PK K + + S A +KG K +
Sbjct: 727 EPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIK 786
Query: 1299 LSQRSLDYVAQLRDHGKTVGVVDT--------------RKKTKLISPQNLSVRNNKKLLT 1344
++ + VA G T V +++ + SP++L+ + + L
Sbjct: 787 KEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLT--KDFEELK 844
Query: 1345 SQELQMQRQIRPKSQ--KNRRRLSDCESTD 1372
++E+ + + I+P+ + ++ +L + E +
Sbjct: 845 AEEVDVTKDIKPQLELIEDEEKLKETEPVE 874
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 42.4 bits (98), Expect = 0.006
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query: 2536 LQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPT-GEPGFPVVHQDLSHIQQPAAVV 2594
++D R+ ++ + + QP P PGATPPT +P FP+V Q L H Q
Sbjct: 3262 IEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQH----T 3317
Query: 2595 AALSSHKPPVR 2605
+S H PVR
Sbjct: 3318 TVISGHTSPVR 3328
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 42.4 bits (98), Expect = 0.006
Identities = 82/367 (22%), Positives = 142/367 (38%), Gaps = 46/367 (12%)
Query: 744 TRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKTKVQKDEICAKLSHV--IKKQHRK 801
T L ++ T+ L +S+S + L ++ R TKV K+ + K V ++ Q R+
Sbjct: 1224 TEALLEAKTNELINISSSKTNAILS--RISHCQHRTTKV-KEALLIKTCTVSELEAQLRQ 1280
Query: 802 STLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPSGVLDDKNGEQKSQNN 861
T NT+N+ +E K+ ++ I +L + + + +Q++ +
Sbjct: 1281 LTEEQNTLNISFQQATHQLEE----KENQIKSMKADIESLVTEKEALQKEGGNQQQAASE 1336
Query: 862 VLPKEKQLKNE-----ELVIFSFHENNCKIQEFHVDGKELIPFTEMTNASEKKSSPFKDL 916
QLK E V E K E K+L S S +
Sbjct: 1337 KESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAI 1396
Query: 917 MTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRDLHKLSLLAQASVITF 976
++ + DEE +Q D+S K DTL+ K+S L Q
Sbjct: 1397 SSLRKQYDEEKCELL---------DQVQDLSFKVDTLSKE-------KISALEQVD---- 1436
Query: 977 PSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKLTKQ 1036
D S+ ++K + FT +QN V + + ++ + D++ L E+L +Q
Sbjct: 1437 --DWSNKFSEWKKKAQSR---FTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQ 1491
Query: 1037 DK--ICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESD---SQCFEFESSSEVFS 1091
+K CL+ E + + K+E N E K++T E D + E ES +EV
Sbjct: 1492 NKRFDCLKGEMEDD--KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLK 1549
Query: 1092 VWQDHPD 1098
+ D
Sbjct: 1550 NYNQQKD 1556
Score = 34.7 bits (78), Expect = 1.3
Identities = 100/522 (19%), Positives = 194/522 (37%), Gaps = 77/522 (14%)
Query: 664 IEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISSYTP 723
+E + N+ N V +E H LK ++TE K+ KQ+ E+
Sbjct: 594 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTE------KLQVLKQQYQTEMEKLRE 647
Query: 724 KDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKTKVQ 783
K C++ LL D + NE L K ++T++
Sbjct: 648 K-----------CEQ---EKETLLKDKEIIFQAHIEEMNE------KTLEKLDVKQTEL- 686
Query: 784 KDEICAKLSHVIKKQHR----KSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFI- 838
+ + ++LS V+K +H+ S L D T + + L E +K+ Q+ D I
Sbjct: 687 -ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE----QKNHHQQQVDSIIK 741
Query: 839 -HNLSLDPSGVLDDKNGEQKSQNNVLPKE--KQLKNEELVIFSFHENNCKIQ-EFHVDGK 894
H +S+ + + +Q +Q +L KE K LK + + + + + + E
Sbjct: 742 EHEVSIQRT---EKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASA 798
Query: 895 ELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLT 954
+L F +A+ +++ +++ + + + ++ + LT++ A + K D T
Sbjct: 799 KLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL----LTKQVAEVEAQKKDVCT 854
Query: 955 DSQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTA--NQNNVGDTSRGQ 1012
+ D HK+ V + +S++++KVK + + + N Q
Sbjct: 855 ----ELDAHKI------QVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQ 904
Query: 1013 VIIISDS-------DDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVK-E 1064
+++ ++ + IL+ + K+D I + E E K EK K +
Sbjct: 905 ILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAK 964
Query: 1065 EKTETLFQFEESDSQCFEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCT 1124
E ETL + + E + + Q N + + + N G +
Sbjct: 965 EMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQ---------ANSAGIS 1015
Query: 1125 DYVSEVVKKGAEGIEEHTRPRSISVEEFCEIEVKKPKRKRSE 1166
D VS + E IE T + + I KK ++ E
Sbjct: 1016 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEE 1057
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 42.4 bits (98), Expect = 0.006
Identities = 67/375 (17%), Positives = 137/375 (36%), Gaps = 61/375 (16%)
Query: 1132 KKGAEGIEEHTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKR 1191
+KG E + E +P + + E + K K K +A++ + ++ ++E + K+
Sbjct: 168 EKGKEKVREKEKPEKKATHK----EKIEKKEKPETKTLAKEQKKAKTAEKSE---EKTKK 220
Query: 1192 DLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKK------- 1244
++ G + + ++T+ +Q+ + ++K K K VSK +K
Sbjct: 221 EVKGGKQEKV-KQTAAKVKEVQKTPSKPKEKEDK--------EKAAVSKHEQKDQYAFCR 271
Query: 1245 ------THSDAKKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYE 1298
H D K GQ+ PAI PP Q PT + L K+G +K E
Sbjct: 272 YMIDIFVHGDLKPGQS-----------PAIPPPLPTEQASRPTPASPALEEKEGEKKKAE 320
Query: 1299 ---LSQRSLDYVAQLRDHGKTVGVVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIR 1355
S+ ++ + +D KK P S + + + ++ +
Sbjct: 321 KKVTSETKKKEKEDIKKKSEKETAIDVEKK----EPGKASETKQGTVKIAAQAAAKKDEK 376
Query: 1356 PKSQKNRRRLSDCESTDVKRAGSHTAQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIK 1415
+ K ++ ++ E K+ + + +S + +++ +V A + R +
Sbjct: 377 KEDSKKTKKPAEVEQPKGKK---QEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAK--- 430
Query: 1416 CMPSEPETIKAKHGSPATDDACPLNQCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHI 1475
E + K P + + + I+ E P+ G +
Sbjct: 431 ---EEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKE-PIKGKEEKV--- 483
Query: 1476 EMAALKEGEPDSSSD 1490
A+LKE EP++ D
Sbjct: 484 -PASLKEKEPETKKD 497
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
[Homo sapiens]
Length = 513
Score = 42.0 bits (97), Expect = 0.008
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 42/262 (16%)
Query: 791 LSHVIKKQHRKSTLV--DNTINLDENLTVSNIESFYSR----KDTGVQ------KGDG-- 836
L H +K RKS + D+ LD+N T+ ++S + +DTG+ KGD
Sbjct: 260 LEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQE 319
Query: 837 -FIHNLSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKE 895
NLS + S +D + E + N+ +E +++E V+ +N +V+ +
Sbjct: 320 DSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ- 378
Query: 896 LIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTD 955
E +++SE+ SS L EE ++S S N + E SP+S +
Sbjct: 379 -----EDSDSSEEDSS--HTLSHSKSESREEQADSESSESLNFSEE-----SPESPEDEN 426
Query: 956 SQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVII 1015
S L S A++ S+ + SQ + KED + ++ D + I
Sbjct: 427 SSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEI 486
Query: 1016 --------------ISDSDDDD 1023
I D DD+D
Sbjct: 487 ESRKLTVDAYHNKPIGDQDDND 508
Score = 32.0 bits (71), Expect = 8.4
Identities = 49/217 (22%), Positives = 76/217 (35%), Gaps = 28/217 (12%)
Query: 899 FTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQI 958
F + + E S D T+ E + + NS S P+ D+ DSQ
Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNS--------RDTGLSQPRRDSKGDSQE 319
Query: 959 DRDLHKLSLLAQASVITFPSDSPQ--------NSSQLQRKVKEDKRCFTANQNNVGDTSR 1010
D LS +V S+S Q NSS+ Q +V + R GD
Sbjct: 320 DSK-ENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR---------GDNPD 369
Query: 1011 GQVIIISDSDDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETL 1070
+ D +D D S L+ E + + ++N EE E++ +
Sbjct: 370 PTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSS 429
Query: 1071 FQFEESDSQCFEFESSSEVFSVWQDHPDDNNSVQDGE 1107
+ +S S ES SE +D D +S + E
Sbjct: 430 QEGLQSHSS--SAESQSEESHSEEDDSDSQDSSRSKE 464
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 42.0 bits (97), Expect = 0.008
Identities = 62/262 (23%), Positives = 105/262 (40%), Gaps = 42/262 (16%)
Query: 791 LSHVIKKQHRKSTLV--DNTINLDENLTVSNIESFYSR----KDTGVQ------KGDG-- 836
L H +K RKS + D+ LD+N T+ ++S + +DTG+ KGD
Sbjct: 244 LEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQE 303
Query: 837 -FIHNLSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKE 895
NLS + S +D + E + N+ +E +++E V+ +N +V+ +
Sbjct: 304 DSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ- 362
Query: 896 LIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTD 955
E +++SE+ SS L EE ++S S N + E SP+S +
Sbjct: 363 -----EDSDSSEEDSS--HTLSHSKSESREEQADSESSESLNFSEE-----SPESPEDEN 410
Query: 956 SQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVII 1015
S L S A++ S+ + SQ + KED + ++ D + I
Sbjct: 411 SSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEI 470
Query: 1016 --------------ISDSDDDD 1023
I D DD+D
Sbjct: 471 ESRKLTVDAYHNKPIGDQDDND 492
Score = 32.0 bits (71), Expect = 8.4
Identities = 49/217 (22%), Positives = 76/217 (35%), Gaps = 28/217 (12%)
Query: 899 FTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQI 958
F + + E S D T+ E + + NS S P+ D+ DSQ
Sbjct: 252 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNS--------RDTGLSQPRRDSKGDSQE 303
Query: 959 DRDLHKLSLLAQASVITFPSDSPQ--------NSSQLQRKVKEDKRCFTANQNNVGDTSR 1010
D LS +V S+S Q NSS+ Q +V + R GD
Sbjct: 304 DSK-ENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR---------GDNPD 353
Query: 1011 GQVIIISDSDDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETL 1070
+ D +D D S L+ E + + ++N EE E++ +
Sbjct: 354 PTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSS 413
Query: 1071 FQFEESDSQCFEFESSSEVFSVWQDHPDDNNSVQDGE 1107
+ +S S ES SE +D D +S + E
Sbjct: 414 QEGLQSHSS--SAESQSEESHSEEDDSDSQDSSRSKE 448
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 41.2 bits (95), Expect = 0.014
Identities = 44/181 (24%), Positives = 79/181 (43%), Gaps = 18/181 (9%)
Query: 1023 DDERILSLEKLTKQDKICLEREHPEQHVSTVNSKE-----EKNPVKEEKTETLF-QFEES 1076
D+ER + K K + E E Q S+ +E E++ +EE +T + E S
Sbjct: 945 DEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVS 1004
Query: 1077 DSQCFEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAE 1136
D + E +SSS+ S++ D +N+S D E + +++++ + S + +E
Sbjct: 1005 DGEDEESDSSSKC-SLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSE 1063
Query: 1137 GIEEHTR----------PRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQS 1186
EE R PR + V +EV P+R + P+ P + +S R G +
Sbjct: 1064 DEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERV-AGSPVTPLPEQEASPARPAGPT 1122
Query: 1187 D 1187
+
Sbjct: 1123 E 1123
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 40.8 bits (94), Expect = 0.018
Identities = 152/856 (17%), Positives = 279/856 (32%), Gaps = 110/856 (12%)
Query: 892 DGKELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSD 951
D E P +E ++++ K ++ +V + D ++ S ++T I+ +
Sbjct: 113 DNHEAPPTSEENSSNQGKDPMIRNQRSV-DPADSTTTHKESAGKKHITPAPKSKINCRKS 171
Query: 952 TLTDSQIDRDLHKLSLLAQASVITFPSDSPQ------------NSSQLQRKVKEDKRCFT 999
T S + R K + S+ T S NS Q+ ++
Sbjct: 172 TTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITA 231
Query: 1000 ANQNNVGDTSRGQVIIISDSDDDDDERILSLEKLTKQDKICLER----------EHPEQH 1049
A++ T + S+ +D + S + LTK K E P +H
Sbjct: 232 ASKTTYKTTGTPEE---SEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEH 288
Query: 1050 VSTVNSKEEKNPVKEEKTETLFQFEESDSQCFEFE-------SSSEVFSVWQDHPDDNNS 1102
+ E P E TE + ++ E +++E + + P +N
Sbjct: 289 GGRT-ANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENRE 347
Query: 1103 VQDGEKKCLAPIANTTNGQ-----GCTDYVSEVVKKGAEGIEEHTRPRSISVEE------ 1151
+ E L P T +G+ T +E + G E+T P E
Sbjct: 348 MTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTP 407
Query: 1152 FCEIEVKKPKRKRSEK----PMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKSIDRRTST 1207
F + + +E P+A + PS + E + T + + + R +T
Sbjct: 408 FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467
Query: 1208 PNSRI---------QRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSN 1258
N + R TT ++K + TE ++ P + K T S A+ ++
Sbjct: 468 ANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANE-KTTSSSAEPTEHGERT 526
Query: 1259 YLSCR-TTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTV 1317
L+ TTP+ EPT E+ ++++ A+ ++G
Sbjct: 527 PLANENTTPSPA---------EPTENRERTA-----------NEKTTPSPAEPTENGDRT 566
Query: 1318 GVVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAG 1377
+ + + L P N ++ + E P + R L++ +T +
Sbjct: 567 PLANEKTTPSLAEP----TENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTP---SP 619
Query: 1378 SHTAQNSDIFVPESDR-SDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDA 1436
+ +N + E+ S T E+ AN P+EP + + + T +
Sbjct: 620 AEPTENRERTANENTTPSPAGPTENREMTANEKTT----LFPAEPTENRERTANEKTTSS 675
Query: 1437 CPLNQCDSVVLNG--TVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSD--AE 1492
P + NG T NE S+S +P G+ T E L EP + + A
Sbjct: 676 -PAEPTE----NGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTAN 730
Query: 1493 EDNLFLTQNDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYK 1552
E E+ + + EN + D + + + E K
Sbjct: 731 EKTTPFPAEPTENRERTAN-ENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPF 789
Query: 1553 DCLETTKNQGEYCPKHSEVKAADEDVFRKPGLPPP-ASKPLRPTTKIFSSKSTSRIAGLS 1611
+TT + E A+E+ P P + T F ++ T +
Sbjct: 790 ANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA 849
Query: 1612 KSLETSSALSPSLKNK-SKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQ 1670
T P+ + + + L +P P+ K + SP
Sbjct: 850 NEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTL------SPAEPTEN 903
Query: 1671 GCKVPFGESKYFPSSS 1686
G + PF K PSS+
Sbjct: 904 GERTPFTNEKTTPSSA 919
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 40.8 bits (94), Expect = 0.018
Identities = 116/606 (19%), Positives = 227/606 (37%), Gaps = 78/606 (12%)
Query: 613 KISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADNTIEGDNNEQN 672
K++ N E Q+ +T K++ L+ S+E + VQ S+ + + +
Sbjct: 785 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNM 844
Query: 673 YIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEI---SSYTPKDCTSR 729
D++ LA K K+ ER E IK + + + EI S T
Sbjct: 845 LSSDLEKLRENLADMEAKFREKD---EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM 901
Query: 730 NGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKTKVQKDEICA 789
N R +R + LT ++ +A + S ED ++K + + + +K + +K E+
Sbjct: 902 NDELRLKERDVEELQLKLTKANENA-SFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELER 960
Query: 790 KLSHVIKK---QHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPS 846
KLS + KK H + + + T + E + + + + S
Sbjct: 961 KLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENS 1020
Query: 847 GVL----------DDKNGEQKSQNNVLPKEKQLKNEELVIFSFH---ENNCKIQEFHVDG 893
G+L D Q +++ + E+ K + + S + N K+Q
Sbjct: 1021 GLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ------ 1074
Query: 894 KELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVI----------YSNLTREQ- 942
EL E + ++ + K+L+TV + EE + S L E
Sbjct: 1075 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENV 1134
Query: 943 --APDISPKSDTLTDSQIDRD----LHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKR 996
A ++ D +T Q + L+ L + F D+ + + LQ+ +
Sbjct: 1135 KLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSA 1194
Query: 997 CFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSK 1056
T + + R +V ++ ++ + + S+ + + DK+ LE + K
Sbjct: 1195 LLTEKDAEL-EKLRNEVTVLR-GENASAKSLHSVVQTLESDKVKLE----------LKVK 1242
Query: 1057 EEKNPVKEEKTETLFQFEESDSQCFEFESSSE-----VFSVWQDHPDDNNSVQDGEKKCL 1111
+ +KE K + +D+Q E E + E + SV D N ++ + + +
Sbjct: 1243 NLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLK-MKVEMM 1301
Query: 1112 APIANTTNGQGCTDYVSEVVKKGAEGIEEHTRPRSISVEEFCEI----EVKKPKRKRSEK 1167
+ A NG +Y S+ +K + +PR FC+I ++ + ++
Sbjct: 1302 SEAALNGNGDDLNNYDSDDQEK-----QSKKKPRL-----FCDICDCFDLHDTEDCPTQA 1351
Query: 1168 PMAEDP 1173
M+EDP
Sbjct: 1352 QMSEDP 1357
Score = 33.1 bits (74), Expect = 3.8
Identities = 29/120 (24%), Positives = 63/120 (52%), Gaps = 7/120 (5%)
Query: 2015 ELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELP 2074
E+ K + + KC ++ + N + ++ EK ++ + L+ S+ MKK L
Sbjct: 693 EIKVKELEVLQAKCNEQTKVIDNF--TSQLKATEEKLLDLDALR-KASSEGKSEMKK-LR 748
Query: 2075 SHVQAMHKRKEFLDYQLD-ELSRQRALCRG--GREIQRQELDENISKVSKERQELASKIK 2131
++A K+ + L+ + + E S+ ++ R GRE++ L EN+S+VS+ ++ L +++
Sbjct: 749 QQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQ 808
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 40.8 bits (94), Expect = 0.018
Identities = 116/606 (19%), Positives = 227/606 (37%), Gaps = 78/606 (12%)
Query: 613 KISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADNTIEGDNNEQN 672
K++ N E Q+ +T K++ L+ S+E + VQ S+ + + +
Sbjct: 820 KLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNM 879
Query: 673 YIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEI---SSYTPKDCTSR 729
D++ LA K K+ ER E IK + + + EI S T
Sbjct: 880 LSSDLEKLRENLADMEAKFREKD---EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM 936
Query: 730 NGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKTKVQKDEICA 789
N R +R + LT ++ +A + S ED ++K + + + +K + +K E+
Sbjct: 937 NDELRLKERDVEELQLKLTKANENA-SFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELER 995
Query: 790 KLSHVIKK---QHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPS 846
KLS + KK H + + + T + E + + + + S
Sbjct: 996 KLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENS 1055
Query: 847 GVL----------DDKNGEQKSQNNVLPKEKQLKNEELVIFSFH---ENNCKIQEFHVDG 893
G+L D Q +++ + E+ K + + S + N K+Q
Sbjct: 1056 GLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ------ 1109
Query: 894 KELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVI----------YSNLTREQ- 942
EL E + ++ + K+L+TV + EE + S L E
Sbjct: 1110 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENV 1169
Query: 943 --APDISPKSDTLTDSQIDRD----LHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKR 996
A ++ D +T Q + L+ L + F D+ + + LQ+ +
Sbjct: 1170 KLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSA 1229
Query: 997 CFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSK 1056
T + + R +V ++ ++ + + S+ + + DK+ LE + K
Sbjct: 1230 LLTEKDAEL-EKLRNEVTVLR-GENASAKSLHSVVQTLESDKVKLE----------LKVK 1277
Query: 1057 EEKNPVKEEKTETLFQFEESDSQCFEFESSSE-----VFSVWQDHPDDNNSVQDGEKKCL 1111
+ +KE K + +D+Q E E + E + SV D N ++ + + +
Sbjct: 1278 NLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLK-MKVEMM 1336
Query: 1112 APIANTTNGQGCTDYVSEVVKKGAEGIEEHTRPRSISVEEFCEI----EVKKPKRKRSEK 1167
+ A NG +Y S+ +K + +PR FC+I ++ + ++
Sbjct: 1337 SEAALNGNGDDLNNYDSDDQEK-----QSKKKPRL-----FCDICDCFDLHDTEDCPTQA 1386
Query: 1168 PMAEDP 1173
M+EDP
Sbjct: 1387 QMSEDP 1392
Score = 33.1 bits (74), Expect = 3.8
Identities = 29/120 (24%), Positives = 63/120 (52%), Gaps = 7/120 (5%)
Query: 2015 ELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELP 2074
E+ K + + KC ++ + N + ++ EK ++ + L+ S+ MKK L
Sbjct: 728 EIKVKELEVLQAKCNEQTKVIDNF--TSQLKATEEKLLDLDALR-KASSEGKSEMKK-LR 783
Query: 2075 SHVQAMHKRKEFLDYQLD-ELSRQRALCRG--GREIQRQELDENISKVSKERQELASKIK 2131
++A K+ + L+ + + E S+ ++ R GRE++ L EN+S+VS+ ++ L +++
Sbjct: 784 QQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQ 843
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,306,364
Number of Sequences: 37866
Number of extensions: 5147970
Number of successful extensions: 20960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 20228
Number of HSP's gapped (non-prelim): 1001
length of query: 2677
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2557
effective length of database: 13,703,598
effective search space: 35040100086
effective search space used: 35040100086
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.