Guide to the Human Genome
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Search of human proteins with 21361320

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361320 TRK-fused [Homo sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361320 TRK-fused [Homo sapiens]                                  814   0.0  
gi|56090139 TRK-fused [Homo sapiens]                                  814   0.0  
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     68   2e-11
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     68   2e-11
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     67   3e-11
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    65   8e-11
gi|150170670 piccolo isoform 2 [Homo sapiens]                          64   2e-10
gi|150378539 piccolo isoform 1 [Homo sapiens]                          64   2e-10
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    64   2e-10
gi|55750053 atrophin-1 [Homo sapiens]                                  61   2e-09
gi|55750041 atrophin-1 [Homo sapiens]                                  61   2e-09
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    59   8e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       58   2e-08
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       58   2e-08
gi|33286444 mastermind-like 2 [Homo sapiens]                           57   3e-08
gi|162951884 R3H domain containing 2 [Homo sapiens]                    57   3e-08
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       56   5e-08
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       56   5e-08
gi|5454064 RNA binding motif protein 14 [Homo sapiens]                 56   7e-08
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate...    55   9e-08
gi|57165373 glutamate receptor, ionotropic, N-methyl D-aspartate...    55   9e-08
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    55   1e-07
gi|124378039 SEC16 homolog A [Homo sapiens]                            55   1e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    54   2e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    54   2e-07
gi|188536004 zinc finger protein 469 [Homo sapiens]                    54   2e-07
gi|73695473 roquin [Homo sapiens]                                      54   2e-07
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      53   6e-07
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    53   6e-07
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    53   6e-07

>gi|21361320 TRK-fused [Homo sapiens]
          Length = 400

 Score =  814 bits (2103), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKD 60
           MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKD
Sbjct: 1   MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKD 60

Query: 61  EDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLL 120
           EDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLL
Sbjct: 61  EDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLL 120

Query: 121 DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN 180
           DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN
Sbjct: 121 DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN 180

Query: 181 VMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE 240
           VMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE
Sbjct: 181 VMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE 240

Query: 241 GQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAP 300
           GQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAP
Sbjct: 241 GQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAP 300

Query: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR 360
           APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR
Sbjct: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR 360

Query: 361 PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR 400
           PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR
Sbjct: 361 PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR 400


>gi|56090139 TRK-fused [Homo sapiens]
          Length = 400

 Score =  814 bits (2103), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKD 60
           MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKD
Sbjct: 1   MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKD 60

Query: 61  EDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLL 120
           EDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLL
Sbjct: 61  EDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLL 120

Query: 121 DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN 180
           DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN
Sbjct: 121 DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN 180

Query: 181 VMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE 240
           VMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE
Sbjct: 181 VMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE 240

Query: 241 GQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAP 300
           GQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAP
Sbjct: 241 GQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAP 300

Query: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR 360
           APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR
Sbjct: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR 360

Query: 361 PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR 400
           PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR
Sbjct: 361 PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR 400


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 79/256 (30%), Positives = 97/256 (37%), Gaps = 53/256 (20%)

Query: 170 PLKNQDEINKNVMSAFGLTD--DQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQ-PQQ 226
           P    D++ K     +G T+   Q  GPPS P +   G P           P G Q PQ+
Sbjct: 380 PSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGH-GYP---------GQPYGSQTPQR 429

Query: 227 PPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQ 286
            P T        + G  Y Q         Q P    Q P  YG Q    Y  Q  P   Q
Sbjct: 430 YPMTMQGRAQSAMGGLSYTQ---------QIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480

Query: 287 QFQGYGQQPTSQAP--APAFSGQPQ--------------QLPAQPPQQYQASNYPAQTYT 330
           Q   Y QQP SQ P   P++  QPQ              Q P+QPP Q   + YP+Q  T
Sbjct: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540

Query: 331 AQ---TSQPTNYTVAPASQPGMAPSQPGAYQP-RPGFTSLPGSTMTPPP----SGPNPYA 382
            Q    SQP      P SQP  A S     QP +P  ++L      P P    S    Y+
Sbjct: 541 TQQHPQSQP------PYSQP-QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYS 593

Query: 383 RNRPPFGQGYTQPGPG 398
           + R P  Q  +Q   G
Sbjct: 594 QQRFPPPQELSQDSFG 609



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 59/225 (26%), Positives = 80/225 (35%), Gaps = 38/225 (16%)

Query: 193 SGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQ-QQA 251
           S  PS P   +S  P     S++  HP      QPPY+  Q Q+       YQQ Q QQ 
Sbjct: 519 SQQPSQPPHQQSPAPYPSQQSTTQQHPQS----QPPYSQPQAQSP------YQQQQPQQP 568

Query: 252 GYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSG----- 306
                  QA   QPQ    Q +A   Q+  P Q      +G Q +S     +  G     
Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDM 628

Query: 307 ------QPQQLP------AQPPQQYQASNYPAQTYTAQTS---QPTNYTVAPASQPGMAP 351
                 +P  LP         P   + +  P  + +  +S   + +N   +P S P  +P
Sbjct: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFS-PHTSP 687

Query: 352 SQPGAYQPRPGFTSLPGSTM------TPPPSGPNPYARNRPPFGQ 390
             PG   P P     P S          P + P      RPP GQ
Sbjct: 688 HLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQ 732



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 57/222 (25%), Positives = 80/222 (36%), Gaps = 39/222 (17%)

Query: 195 PPSAPA----EDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQ 250
           PP APA      R GTP S A++++ + PP         + + + A Q  G M       
Sbjct: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASAS-SSSSSFAQQRFGAMGGGGPSA 281

Query: 251 AGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQ-PQ 309
           AG G  QP A P   Q             T P   + +QGY     S  P    +G+ P 
Sbjct: 282 AGGGTPQPTATPTLNQLL-----------TSPSSARGYQGYPGGDYSGGPQDGGAGKGPA 330

Query: 310 QLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPAS------------QPGMAPSQPGAY 357
            + +Q      A+   A        +  +  ++P S            QP     Q G  
Sbjct: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKM 390

Query: 358 QPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGY 399
           +P+P   + P S    PPSGP           QG+  PG  Y
Sbjct: 391 RPQPYGGTNPYSQQQGPPSGPQ----------QGHGYPGQPY 422



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 58/213 (27%), Positives = 76/213 (35%), Gaps = 38/213 (17%)

Query: 192 VSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQP--QQPPYTGAQTQAGQIEGQMYQQYQQ 249
           + GP  +P     G+P S+A S S    P   P  Q PP    +  +GQ +  M+    Q
Sbjct: 692 IRGPSPSPV----GSPASVAQSRSGPLSPAAVPGNQMPP----RPPSGQSDSIMHPSMNQ 743

Query: 250 QA-----GYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPT-SQAPAPA 303
            +     GY  + PQ P     Q G   S    Q +G Q       Y Q    S  P   
Sbjct: 744 SSIAQDRGYMQRNPQMPQYSSPQPGSALSPR--QPSGGQIHTGMGSYQQNSMGSYGPQGG 801

Query: 304 FSGQPQQLPAQPPQQYQA---SNYPAQTYTAQTSQPTNYTVAPASQPGMAP--------- 351
             G     P QP   Y A   +NYP+       + P         QPG+ P         
Sbjct: 802 QYGPQGGYPRQP--NYNALPNANYPSAGMAGGIN-PMGAGGQMHGQPGIPPYGTLPPGRM 858

Query: 352 --SQPGAYQPRPGFTSLP---GSTMTPPPSGPN 379
             +  G     P   ++P   GS M PPP G N
Sbjct: 859 SHASMGNRPYGPNMANMPPQVGSGMCPPPGGMN 891



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 65/237 (27%), Positives = 78/237 (32%), Gaps = 65/237 (27%)

Query: 205  GTPDS--IASSSSAAHPPGVQPQQPPYTGAQ-TQAGQIEGQMYQQYQQQAGYGAQQPQAP 261
            GTP      S  +  +    Q  + P  G     A + EG+MY           QQ Q P
Sbjct: 1347 GTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLP 1406

Query: 262  PQQPQ------------------QYGIQYSASYSQQT------GPQQPQQFQGYGQQPTS 297
            P QPQ                  QYG  Y A+ +  T      GPQ    FQ +G+   S
Sbjct: 1407 PAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQ-FGRDRVS 1465

Query: 298  QAPA--------PAFSGQPQQLPAQPPQQ---YQASNYPAQTYTAQTSQPTN-------- 338
              P         P   G P Q  A+  QQ   +Q  N    TY     Q T         
Sbjct: 1466 APPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRN--DMTYNYANRQSTGSAPQGPAY 1523

Query: 339  ----------YTVAPASQPGMAPS----QP--GAYQPRPGFTSLPGSTMTPPPSGPN 379
                      +T   A+  G  PS    QP  G   P P  T  P S   PPPS  N
Sbjct: 1524 HGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQN 1580



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 47/189 (24%), Positives = 60/189 (31%), Gaps = 23/189 (12%)

Query: 220  PGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQ 279
            PG+ P+    TGA  Q   +           + Y  QQ Q   Q+   YG Q+S   +  
Sbjct: 1292 PGIGPEGNMSTGAP-QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS 1350

Query: 280  TGPQQPQQFQGYGQQPTS---------------------QAPAPAFSGQPQQLPAQPPQQ 318
              P   QQ   Y QQ  +                       P     GQPQQ    P Q 
Sbjct: 1351 GSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQP 1410

Query: 319  YQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGP 378
              AS   A   + Q      Y  A  +    A  +  A  P+  F    G      P G 
Sbjct: 1411 QPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGT 1470

Query: 379  NPYARNRPP 387
            N   +N PP
Sbjct: 1471 NA-QQNMPP 1478



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 34/118 (28%), Positives = 42/118 (35%), Gaps = 18/118 (15%)

Query: 294  QPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPS- 352
            QP  Q P+PA SG  Q    Q PQ   +S          T   T ++  P   PGM+ S 
Sbjct: 1127 QPKIQPPSPAGSGSMQ--GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIP-PLPGMSRSN 1183

Query: 353  -----------QPGAYQPRPGFTSLPG---STMTPPPSGPNPYARNRPPFGQGYTQPG 396
                           +Q R   T  PG   S  T    G   Y  N+ P+G     PG
Sbjct: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 79/256 (30%), Positives = 97/256 (37%), Gaps = 53/256 (20%)

Query: 170 PLKNQDEINKNVMSAFGLTD--DQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQ-PQQ 226
           P    D++ K     +G T+   Q  GPPS P +   G P           P G Q PQ+
Sbjct: 380 PSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGH-GYP---------GQPYGSQTPQR 429

Query: 227 PPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQ 286
            P T        + G  Y Q         Q P    Q P  YG Q    Y  Q  P   Q
Sbjct: 430 YPMTMQGRAQSAMGGLSYTQ---------QIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQ 480

Query: 287 QFQGYGQQPTSQAP--APAFSGQPQ--------------QLPAQPPQQYQASNYPAQTYT 330
           Q   Y QQP SQ P   P++  QPQ              Q P+QPP Q   + YP+Q  T
Sbjct: 481 QQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST 540

Query: 331 AQ---TSQPTNYTVAPASQPGMAPSQPGAYQP-RPGFTSLPGSTMTPPP----SGPNPYA 382
            Q    SQP      P SQP  A S     QP +P  ++L      P P    S    Y+
Sbjct: 541 TQQHPQSQP------PYSQP-QAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYS 593

Query: 383 RNRPPFGQGYTQPGPG 398
           + R P  Q  +Q   G
Sbjct: 594 QQRFPPPQELSQDSFG 609



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 59/225 (26%), Positives = 80/225 (35%), Gaps = 38/225 (16%)

Query: 193 SGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQ-QQA 251
           S  PS P   +S  P     S++  HP      QPPY+  Q Q+       YQQ Q QQ 
Sbjct: 519 SQQPSQPPHQQSPAPYPSQQSTTQQHPQS----QPPYSQPQAQSP------YQQQQPQQP 568

Query: 252 GYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSG----- 306
                  QA   QPQ    Q +A   Q+  P Q      +G Q +S     +  G     
Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDM 628

Query: 307 ------QPQQLP------AQPPQQYQASNYPAQTYTAQTS---QPTNYTVAPASQPGMAP 351
                 +P  LP         P   + +  P  + +  +S   + +N   +P S P  +P
Sbjct: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFS-PHTSP 687

Query: 352 SQPGAYQPRPGFTSLPGSTM------TPPPSGPNPYARNRPPFGQ 390
             PG   P P     P S          P + P      RPP GQ
Sbjct: 688 HLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQ 732



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 57/222 (25%), Positives = 80/222 (36%), Gaps = 39/222 (17%)

Query: 195 PPSAPA----EDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQ 250
           PP APA      R GTP S A++++ + PP         + + + A Q  G M       
Sbjct: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASAS-SSSSSFAQQRFGAMGGGGPSA 281

Query: 251 AGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQ-PQ 309
           AG G  QP A P   Q             T P   + +QGY     S  P    +G+ P 
Sbjct: 282 AGGGTPQPTATPTLNQLL-----------TSPSSARGYQGYPGGDYSGGPQDGGAGKGPA 330

Query: 310 QLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPAS------------QPGMAPSQPGAY 357
            + +Q      A+   A        +  +  ++P S            QP     Q G  
Sbjct: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKM 390

Query: 358 QPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGY 399
           +P+P   + P S    PPSGP           QG+  PG  Y
Sbjct: 391 RPQPYGGTNPYSQQQGPPSGPQ----------QGHGYPGQPY 422



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 58/213 (27%), Positives = 76/213 (35%), Gaps = 38/213 (17%)

Query: 192 VSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQP--QQPPYTGAQTQAGQIEGQMYQQYQQ 249
           + GP  +P     G+P S+A S S    P   P  Q PP    +  +GQ +  M+    Q
Sbjct: 692 IRGPSPSPV----GSPASVAQSRSGPLSPAAVPGNQMPP----RPPSGQSDSIMHPSMNQ 743

Query: 250 QA-----GYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPT-SQAPAPA 303
            +     GY  + PQ P     Q G   S    Q +G Q       Y Q    S  P   
Sbjct: 744 SSIAQDRGYMQRNPQMPQYSSPQPGSALSPR--QPSGGQIHTGMGSYQQNSMGSYGPQGG 801

Query: 304 FSGQPQQLPAQPPQQYQA---SNYPAQTYTAQTSQPTNYTVAPASQPGMAP--------- 351
             G     P QP   Y A   +NYP+       + P         QPG+ P         
Sbjct: 802 QYGPQGGYPRQP--NYNALPNANYPSAGMAGGIN-PMGAGGQMHGQPGIPPYGTLPPGRM 858

Query: 352 --SQPGAYQPRPGFTSLP---GSTMTPPPSGPN 379
             +  G     P   ++P   GS M PPP G N
Sbjct: 859 SHASMGNRPYGPNMANMPPQVGSGMCPPPGGMN 891



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 44/156 (28%), Positives = 55/156 (35%), Gaps = 13/156 (8%)

Query: 220  PGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQ 279
            PG+ P+    TGA  Q   +           + Y  QQ Q   Q+   YG Q+S   +  
Sbjct: 1292 PGIGPEGNMSTGAP-QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS 1350

Query: 280  TGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNY 339
              P   QQ   Y QQ    +PAP        LP     +   S  P   ++    Q    
Sbjct: 1351 GSPFPSQQTTMYQQQQQVSSPAP--------LPRPMENRTSPSKSPF-LHSGMKMQKAGP 1401

Query: 340  TVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPP 375
             V PAS    AP QP     R   T  PGS     P
Sbjct: 1402 PV-PASHIAPAPVQPPMI--RRDITFPPGSVEATQP 1434



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 34/118 (28%), Positives = 42/118 (35%), Gaps = 18/118 (15%)

Query: 294  QPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPS- 352
            QP  Q P+PA SG  Q    Q PQ   +S          T   T ++  P   PGM+ S 
Sbjct: 1127 QPKIQPPSPAGSGSMQ--GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIP-PLPGMSRSN 1183

Query: 353  -----------QPGAYQPRPGFTSLPG---STMTPPPSGPNPYARNRPPFGQGYTQPG 396
                           +Q R   T  PG   S  T    G   Y  N+ P+G     PG
Sbjct: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG 1241


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 55/205 (26%), Positives = 73/205 (35%), Gaps = 4/205 (1%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPPS P + +   P           PPG     PP  G + Q     G+   Q     G 
Sbjct: 49  GPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPPQGD 106

Query: 254 GAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPA 313
            ++ P++PP +PQ  G         Q  P  P + QG   Q  ++   P   G+PQ  P 
Sbjct: 107 KSRSPRSPPGKPQ--GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164

Query: 314 QPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTP 373
           Q   + ++S  P         Q  N    P   PG     P     +P     PG    P
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 224

Query: 374 PPSGPNPYARNRPPFGQGYTQPGPG 398
           PP G N     R P G+    P  G
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQG 249



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 64/208 (30%), Positives = 72/208 (34%), Gaps = 20/208 (9%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP  P + +   P     S SA  PPG     PP  G Q Q         Q    Q G 
Sbjct: 214 GPPP-PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 272

Query: 254 GAQQPQAP--PQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQL 311
             Q P  P  PQ P   G   S S     G  Q    QG G QP    P P   G+PQ  
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG-GNQPQGPPPPP---GKPQGP 328

Query: 312 PAQPPQQYQASNYPA--QTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGS 369
           P Q   + Q    P   Q    Q    +    +P  +P   P Q G     P        
Sbjct: 329 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP-------- 380

Query: 370 TMTPPPSGPNPYARNRPPFGQGYTQPGP 397
              PPP+G NP     PP GQ    P P
Sbjct: 381 ---PPPAGGNPQQPQAPPAGQPQGPPRP 405



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 52/206 (25%), Positives = 71/206 (34%), Gaps = 2/206 (0%)

Query: 193 SGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAG 252
           S  P +P     G P    +      PP  +PQ PP  G     G       Q    Q  
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 167

Query: 253 YGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLP 312
             ++  ++PP +PQ  G         Q  P  P + QG   Q  ++   P   G+PQ  P
Sbjct: 168 NKSRSSRSPPGKPQ--GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 225

Query: 313 AQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMT 372
            Q   + Q++  P         Q  N    P   PG     P     +P     PG    
Sbjct: 226 PQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285

Query: 373 PPPSGPNPYARNRPPFGQGYTQPGPG 398
           PPP G +    +R P G+    P  G
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQG 311



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 52/201 (25%), Positives = 68/201 (33%), Gaps = 6/201 (2%)

Query: 195 PPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYG 254
           PP  P     G P    +      PP  +PQ PP  G     G       Q    Q    
Sbjct: 176 PPGKP----QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 255 AQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQ 314
           +Q  ++PP +PQ  G         Q  P  P + QG   Q  ++   P   G+PQ  P Q
Sbjct: 232 SQSARSPPGKPQ--GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 289

Query: 315 PPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPP 374
              + ++S  P         Q  N    P   PG     P     +P     PG    PP
Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 349

Query: 375 PSGPNPYARNRPPFGQGYTQP 395
           P G +     R P G+    P
Sbjct: 350 PQGGSKSRSARSPPGKPQGPP 370



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 61/207 (29%), Positives = 76/207 (36%), Gaps = 11/207 (5%)

Query: 196 PSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGA 255
           PS  A +  G P    +       P  +PQ PP  G     G        Q     G   
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88

Query: 256 QQPQAPPQQPQQYGIQYSASYSQQTGPQQPQ--QFQGYGQQPTSQAPAPAFSGQPQQLPA 313
            Q   PP +PQ    Q   S S ++ P +PQ    QG G QP    P P   G+PQ  P 
Sbjct: 89  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG-GNQPQGPPPPP---GKPQGPPP 144

Query: 314 QPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPG--MAPSQPGAYQPRPGFTSLPGSTM 371
           Q   + Q    P +       Q  N + +  S PG    P   G  QP+ G    PG   
Sbjct: 145 QGGNKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQ 202

Query: 372 TPPPSGPNPYARNRPPFGQGYTQPGPG 398
            PPP G N   +  PP G+    P  G
Sbjct: 203 GPPPQGGNK-PQGPPPPGKPQGPPPQG 228



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 25/95 (26%), Positives = 32/95 (33%), Gaps = 1/95 (1%)

Query: 294 QPTSQAPAPAF-SGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPS 352
           +  SQ  +P+  +G PQ  P Q   + Q    P         Q  N    P   PG    
Sbjct: 21  EDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 80

Query: 353 QPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPP 387
            P     +P     PG    PPP G    +   PP
Sbjct: 81  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 115


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 67/208 (32%), Positives = 76/208 (36%), Gaps = 22/208 (10%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP  P     G P     S S   PPG     PP  G Q Q         Q    Q G 
Sbjct: 131 GPP--PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188

Query: 254 GAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQ--QFQGYGQQPTSQAPAPAFSGQPQQL 311
             Q P  PP +PQ    Q   S S Q+ P +PQ    QG G QP    P P   G+PQ  
Sbjct: 189 KPQGPP-PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG-GNQPQGPPPPP---GKPQGP 243

Query: 312 PAQPPQQYQASNYPA--QTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGS 369
           P Q   + Q    P   Q   AQ    +    +P  +P   P Q G     P        
Sbjct: 244 PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP-------- 295

Query: 370 TMTPPPSGPNPYARNRPPFGQGYTQPGP 397
              PPP+G NP     PP GQ    P P
Sbjct: 296 ---PPPAGGNPQQPQAPPAGQPQGPPRP 320



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 69/234 (29%), Positives = 92/234 (39%), Gaps = 44/234 (18%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP  P + + G P    +      PPG +PQ PP  G ++++ +      Q    Q G 
Sbjct: 49  GPPPPPGKPQ-GPPPQGGNKPQGPPPPG-KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 106

Query: 254 GAQQPQAPPQQPQ----QYG----------------IQYSASYSQQTGPQQPQ--QFQGY 291
             Q P  PP +PQ    Q G                 Q   S S ++ P +PQ    QG 
Sbjct: 107 QPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG- 165

Query: 292 GQQPTSQAPAPAFSGQPQQLPAQ-------PPQQYQASNYPAQTYTAQTSQPTNYTVAPA 344
           G QP    P P   G+PQ  P Q       PP   +    P Q   +++SQ      +P 
Sbjct: 166 GNQPQGPPPPP---GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ------SPP 216

Query: 345 SQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPG 398
            +P   P Q G  QP+ G    PG    PPP G N   +  PP G+    P  G
Sbjct: 217 GKPQGPPPQ-GGNQPQ-GPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQGPPAQG 267



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 49/196 (25%), Positives = 67/196 (34%), Gaps = 11/196 (5%)

Query: 192 VSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQA 251
           ++G P  P+      P           PP  +PQ PP  G     G       Q    Q 
Sbjct: 32  IAGNPQGPSPQGGNKPQG-------PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ- 83

Query: 252 GYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQL 311
           G  ++ P++PP +PQ  G         Q  P  P + QG   Q  ++   P   G+PQ  
Sbjct: 84  GDKSRSPRSPPGKPQ--GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141

Query: 312 PAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTM 371
           P Q  +     + P +       Q  N    P   PG     P     +P     PG   
Sbjct: 142 PPQGDKSRSPRSPPGKP-QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200

Query: 372 TPPPSGPNPYARNRPP 387
            PPP G    +   PP
Sbjct: 201 GPPPQGDKSRSSQSPP 216


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 71/217 (32%), Positives = 86/217 (39%), Gaps = 26/217 (11%)

Query: 191 QVSGPPSAPAEDR-SGTPDSIASSSSA-AHPPGV---QPQQPPYTGAQTQAGQIEGQMYQ 245
           Q  GP   PA+   S  P S      A A PPGV     QQP      TQ       + Q
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423

Query: 246 QYQQQAGYGAQQP-QAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAF 304
           Q   Q+   A  P + P QQP    I      +QQ GP +    Q    +P SQ P PA 
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIP-----AQQAGPGKTSAQQTGPTKPPSQLPGPAK 478

Query: 305 SGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMA---PSQPGAYQP-- 359
               Q  PA+PP Q   S  P        SQ    T  P  QPG A   P QPG+ +P  
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKP-------PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531

Query: 360 -RPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQP 395
            +PG  S   S   P P+ P+     +P    G  +P
Sbjct: 532 QQPG--SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 72/292 (24%), Positives = 110/292 (37%), Gaps = 31/292 (10%)

Query: 124 EPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMS 183
           + P +P P    P  D +  +++ +    S +Q  ++ +       P++   +  +   +
Sbjct: 213 QQPPKPIPKQQGPGRDPL--QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270

Query: 184 AFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQM 243
              L  D  S P +  A+   G  +S+  S  +   P +Q   P    AQ Q G  + Q 
Sbjct: 271 KLPLQRD-ASRPQTKQADIVRG--ESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQP 326

Query: 244 YQQYQQQAGYGAQQPQA-------PPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPT 296
                     G  +P A       PP QP       +   +Q  GP +P   Q   ++P+
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT----TKPPAQPLGPAKPPAQQTGSEKPS 382

Query: 297 SQAPAPAFSGQP---------QQLPAQPPQQYQASNYP--AQTYTAQTSQPTNYTVAPAS 345
           S+ P P    QP         Q  PA+PP Q   +  P   Q      ++    T  P  
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 346 QPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
           QPG  P +  A Q  PG TS   +  T PPS   P     PP   G  +P P
Sbjct: 443 QPG--PGKIPAQQAGPGKTSAQQTGPTKPPS-QLPGPAKPPPQQPGPAKPPP 491



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 78/338 (23%), Positives = 110/338 (32%), Gaps = 93/338 (27%)

Query: 122 SLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNV 181
           +++PP +P P T  P    +   +  +    S K S++       A  P           
Sbjct: 348 TVKPPVQP-PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP----------- 395

Query: 182 MSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHP-----PGVQPQQPPYTGA---- 232
               G T  Q  GP   P + + GTP  +A       P     P   P Q P  G     
Sbjct: 396 --GVGKTPAQQPGPAKPPTQ-QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 233 QTQAGQIEGQMY------QQYQQQAGYGAQQP---QAPPQQP-------QQYGIQYSASY 276
           Q   G+   Q         Q    A    QQP   + PPQQP       QQ G   +   
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPP 510

Query: 277 SQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQP 336
            QQ GP +P   Q    +P SQ P  A     Q  PA+P  Q Q++   +QT + +  QP
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQP 569

Query: 337 TNYTVAPASQPGMAPSQPGA-----------------------------------YQPRP 361
              TV+P+++   +   P                                     + P P
Sbjct: 570 P--TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627

Query: 362 GFTSLP-------------GSTMTPPPSGPNPYARNRP 386
             T +              G  + P PS P P  +  P
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 40/125 (32%), Positives = 46/125 (36%), Gaps = 12/125 (9%)

Query: 200  AEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQI-------EGQMYQQYQQQAG 252
            AEDR    DS  SS+           + P T  QT+  Q        E Q+         
Sbjct: 3828 AEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQ 3887

Query: 253  YGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLP 312
            Y    P  P Q P  Y  Q  + + QQT     QQ   Y  QPT QA A   S  PQ  P
Sbjct: 3888 YQYSSPALPTQAPTSYTQQ--SHFEQQT--LYHQQVSPYQTQPTFQAVA-TMSFTPQVQP 3942

Query: 313  AQPPQ 317
               PQ
Sbjct: 3943 TPTPQ 3947



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 65/291 (22%), Positives = 100/291 (34%), Gaps = 41/291 (14%)

Query: 121 DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN 180
           DSL  P  P   +   E D     ++K       K +T ++++S +   P    D  +  
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP----DIPSSK 782

Query: 181 VMS-AFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHP-PGVQPQQPPYTGAQTQA-G 237
           V S A   T   +    + P++    T + ++   S A P P    +   + G  +++ G
Sbjct: 783 VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG 842

Query: 238 QIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTS 297
           Q +    Q+ ++      +    P  +P   G            P  P      G +PT+
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG-----------SPTPP------GPRPTA 885

Query: 298 QAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTN-----------YTVAPASQ 346
               P     PQQ P    Q  + S        A  SQPT            +  +  SQ
Sbjct: 886 GQTVPT----PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941

Query: 347 PGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
                S  G  QP P   S PG+ M   P+   P     PP   G   P P
Sbjct: 942 ASNLISTAG--QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 13/125 (10%)

Query: 278 QQTGPQQPQQFQGYGQQPTSQ--APAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQ 335
           QQ  P+   + QG G+ P  Q   P    S QP+++ +QPP   +    P Q  T QT  
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ--TPQTDH 269

Query: 336 PTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPF---GQGY 392
                   AS+P     Q    +      SLP S   PP   P P    +PP    G   
Sbjct: 270 AKLPLQRDASRP--QTKQADIVRGESVKPSLP-SPSKPPIQQPTP---GKPPAQQPGHEK 323

Query: 393 TQPGP 397
           +QPGP
Sbjct: 324 SQPGP 328



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 45/213 (21%), Positives = 74/213 (34%), Gaps = 28/213 (13%)

Query: 196  PSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGA 255
            P       S  PD+      +  PPG +P          Q+ + + Q  +++    G   
Sbjct: 855  PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS-RRFSLNLGSIT 913

Query: 256  QQPQAPPQQPQQ--------YGIQYSASYSQ------------QTGPQQP-QQFQGYGQQ 294
              P++ P  PQ+        +G    +  S             Q+GP  P +Q     Q 
Sbjct: 914  DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973

Query: 295  PTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQP 354
            PTSQ P P  +GQ    PA+     + +  PA    A+  +P     AP  +      +P
Sbjct: 974  PTSQGP-PKSTGQAPPAPAKSIPVKKETKAPA----AEKLEP-KAEQAPTVKRTETEKKP 1027

Query: 355  GAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPP 387
               +     T+ P   + P     +P   +  P
Sbjct: 1028 PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 7/97 (7%)

Query: 293  QQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPS 352
            ++  S      F   P  + A P ++  ++ Y     T    +P +    P+  P ++ S
Sbjct: 2329 ERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQL--PSGSPSVS-S 2385

Query: 353  QPGAYQPRPGF--TSLPGSTMTPPPSGPNPYARNRPP 387
             P   +PRP F  +SL  S   PPP  P P     PP
Sbjct: 2386 LPA--KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 71/217 (32%), Positives = 86/217 (39%), Gaps = 26/217 (11%)

Query: 191 QVSGPPSAPAEDR-SGTPDSIASSSSA-AHPPGV---QPQQPPYTGAQTQAGQIEGQMYQ 245
           Q  GP   PA+   S  P S      A A PPGV     QQP      TQ       + Q
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423

Query: 246 QYQQQAGYGAQQP-QAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAF 304
           Q   Q+   A  P + P QQP    I      +QQ GP +    Q    +P SQ P PA 
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIP-----AQQAGPGKTSAQQTGPTKPPSQLPGPAK 478

Query: 305 SGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMA---PSQPGAYQP-- 359
               Q  PA+PP Q   S  P        SQ    T  P  QPG A   P QPG+ +P  
Sbjct: 479 PPPQQPGPAKPPPQQPGSAKP-------PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531

Query: 360 -RPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQP 395
            +PG  S   S   P P+ P+     +P    G  +P
Sbjct: 532 QQPG--SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 72/292 (24%), Positives = 110/292 (37%), Gaps = 31/292 (10%)

Query: 124 EPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMS 183
           + P +P P    P  D +  +++ +    S +Q  ++ +       P++   +  +   +
Sbjct: 213 QQPPKPIPKQQGPGRDPL--QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270

Query: 184 AFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQM 243
              L  D  S P +  A+   G  +S+  S  +   P +Q   P    AQ Q G  + Q 
Sbjct: 271 KLPLQRD-ASRPQTKQADIVRG--ESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQP 326

Query: 244 YQQYQQQAGYGAQQPQA-------PPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPT 296
                     G  +P A       PP QP       +   +Q  GP +P   Q   ++P+
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT----TKPPAQPLGPAKPPAQQTGSEKPS 382

Query: 297 SQAPAPAFSGQP---------QQLPAQPPQQYQASNYP--AQTYTAQTSQPTNYTVAPAS 345
           S+ P P    QP         Q  PA+PP Q   +  P   Q      ++    T  P  
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 346 QPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
           QPG  P +  A Q  PG TS   +  T PPS   P     PP   G  +P P
Sbjct: 443 QPG--PGKIPAQQAGPGKTSAQQTGPTKPPS-QLPGPAKPPPQQPGPAKPPP 491



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 78/338 (23%), Positives = 110/338 (32%), Gaps = 93/338 (27%)

Query: 122 SLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNV 181
           +++PP +P P T  P    +   +  +    S K S++       A  P           
Sbjct: 348 TVKPPVQP-PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP----------- 395

Query: 182 MSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHP-----PGVQPQQPPYTGA---- 232
               G T  Q  GP   P + + GTP  +A       P     P   P Q P  G     
Sbjct: 396 --GVGKTPAQQPGPAKPPTQ-QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 233 QTQAGQIEGQMY------QQYQQQAGYGAQQP---QAPPQQP-------QQYGIQYSASY 276
           Q   G+   Q         Q    A    QQP   + PPQQP       QQ G   +   
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPP 510

Query: 277 SQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQP 336
            QQ GP +P   Q    +P SQ P  A     Q  PA+P  Q Q++   +QT + +  QP
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQP 569

Query: 337 TNYTVAPASQPGMAPSQPGA-----------------------------------YQPRP 361
              TV+P+++   +   P                                     + P P
Sbjct: 570 P--TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627

Query: 362 GFTSLP-------------GSTMTPPPSGPNPYARNRP 386
             T +              G  + P PS P P  +  P
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAP 665



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 40/125 (32%), Positives = 46/125 (36%), Gaps = 12/125 (9%)

Query: 200  AEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQI-------EGQMYQQYQQQAG 252
            AEDR    DS  SS+           + P T  QT+  Q        E Q+         
Sbjct: 3828 AEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQ 3887

Query: 253  YGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLP 312
            Y    P  P Q P  Y  Q  + + QQT     QQ   Y  QPT QA A   S  PQ  P
Sbjct: 3888 YQYSSPALPTQAPTSYTQQ--SHFEQQT--LYHQQVSPYQTQPTFQAVA-TMSFTPQVQP 3942

Query: 313  AQPPQ 317
               PQ
Sbjct: 3943 TPTPQ 3947



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 65/291 (22%), Positives = 100/291 (34%), Gaps = 41/291 (14%)

Query: 121 DSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKN 180
           DSL  P  P   +   E D     ++K       K +T ++++S +   P    D  +  
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP----DIPSSK 782

Query: 181 VMS-AFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHP-PGVQPQQPPYTGAQTQA-G 237
           V S A   T   +    + P++    T + ++   S A P P    +   + G  +++ G
Sbjct: 783 VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG 842

Query: 238 QIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTS 297
           Q +    Q+ ++      +    P  +P   G            P  P      G +PT+
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG-----------SPTPP------GPRPTA 885

Query: 298 QAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTN-----------YTVAPASQ 346
               P     PQQ P    Q  + S        A  SQPT            +  +  SQ
Sbjct: 886 GQTVPT----PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941

Query: 347 PGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
                S  G  QP P   S PG+ M   P+   P     PP   G   P P
Sbjct: 942 ASNLISTAG--QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 13/125 (10%)

Query: 278 QQTGPQQPQQFQGYGQQPTSQ--APAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQ 335
           QQ  P+   + QG G+ P  Q   P    S QP+++ +QPP   +    P Q  T QT  
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ--TPQTDH 269

Query: 336 PTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPF---GQGY 392
                   AS+P     Q    +      SLP S   PP   P P    +PP    G   
Sbjct: 270 AKLPLQRDASRP--QTKQADIVRGESVKPSLP-SPSKPPIQQPTP---GKPPAQQPGHEK 323

Query: 393 TQPGP 397
           +QPGP
Sbjct: 324 SQPGP 328



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 45/213 (21%), Positives = 74/213 (34%), Gaps = 28/213 (13%)

Query: 196  PSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGA 255
            P       S  PD+      +  PPG +P          Q+ + + Q  +++    G   
Sbjct: 855  PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS-RRFSLNLGSIT 913

Query: 256  QQPQAPPQQPQQ--------YGIQYSASYSQ------------QTGPQQP-QQFQGYGQQ 294
              P++ P  PQ+        +G    +  S             Q+GP  P +Q     Q 
Sbjct: 914  DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973

Query: 295  PTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQP 354
            PTSQ P P  +GQ    PA+     + +  PA    A+  +P     AP  +      +P
Sbjct: 974  PTSQGP-PKSTGQAPPAPAKSIPVKKETKAPA----AEKLEP-KAEQAPTVKRTETEKKP 1027

Query: 355  GAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPP 387
               +     T+ P   + P     +P   +  P
Sbjct: 1028 PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 7/97 (7%)

Query: 293  QQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPS 352
            ++  S      F   P  + A P ++  ++ Y     T    +P +    P+  P ++ S
Sbjct: 2329 ERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQL--PSGSPSVS-S 2385

Query: 353  QPGAYQPRPGF--TSLPGSTMTPPPSGPNPYARNRPP 387
             P   +PRP F  +SL  S   PPP  P P     PP
Sbjct: 2386 LPA--KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 62/228 (27%), Positives = 76/228 (33%), Gaps = 20/228 (8%)

Query: 190 DQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQA-----GQIEGQMY 244
           +Q  GPP  P +     P     S      PG    QPP  G Q+Q      G+ EG   
Sbjct: 66  NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPP 125

Query: 245 QQYQQQAG-------------YGAQQPQAPPQQP-QQYGIQYSASYSQQTGPQQPQQFQG 290
           Q   Q  G              G  Q Q PP +P +  G         Q  P  P + +G
Sbjct: 126 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEG 185

Query: 291 YGQQPTSQAPAPA-FSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGM 349
              Q  +Q+  P    G+P+  P Q   Q Q             SQ  N    P   PG 
Sbjct: 186 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGK 245

Query: 350 APSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
               P     +P     PG    PPP G NP     PP G+    P P
Sbjct: 246 PQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPP 293



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 65/232 (28%), Positives = 77/232 (33%), Gaps = 24/232 (10%)

Query: 183 SAFGLTDD--QVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQA---- 236
           SA  L +D  Q   P     +     P           PPG    +PP  G Q+Q     
Sbjct: 15  SAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPR 74

Query: 237 -GQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQP 295
            G+ EG   Q   Q  G    +P  P  QP Q G Q      +   P+ P   QG  Q  
Sbjct: 75  PGKPEGPPPQGGNQSQG-PPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPP-QGGNQ-- 130

Query: 296 TSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQP- 354
            SQ P P   G+P+  P Q   Q Q              Q  N +  P   PG     P 
Sbjct: 131 -SQGPPPR-PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPP 188

Query: 355 -GAYQPRPGFTSLPGSTMTPPPSG--------PNPYARNRPPFGQGYTQPGP 397
            G  Q + G    PG    PPP G        P P     PP   G    GP
Sbjct: 189 QGGNQSQ-GPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP 239



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 37/128 (28%), Positives = 45/128 (35%), Gaps = 3/128 (2%)

Query: 190 DQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQ 249
           +Q  GPP  P +     P     S      PG     PP  G Q+Q         +    
Sbjct: 171 NQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPS 230

Query: 250 QAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQ 309
           Q G   Q P   P +PQ    Q      +   P +PQ     G  P    P PA  G+PQ
Sbjct: 231 QGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPA--GKPQ 288

Query: 310 QLPAQPPQ 317
             P  PPQ
Sbjct: 289 G-PPPPPQ 295


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 77/313 (24%), Positives = 103/313 (32%), Gaps = 62/313 (19%)

Query: 129 PGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMS------AFDP---LKNQDEINK 179
           P P    P + +       S+S SS   S     AS +      +F P   L   ++  K
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPK 426

Query: 180 NVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQI 239
               +         GPP  P   R         ++S AHP       PP TGAQ+ A   
Sbjct: 427 YTQPSLPSQAVWSQGPPPPPPYGR-------LLANSNAHPGPF----PPSTGAQSTAHPP 475

Query: 240 EGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQF----------- 288
               +  +QQQ     QQ Q   QQ Q +G          +GP  P  F           
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHG---------NSGPPPPGAFPHPLEGGSSHH 526

Query: 289 -QGYGQQPTSQAPAPAFSGQPQQLP---AQPPQQYQASNYPAQTYTAQTSQPTNYTVAPA 344
              Y   P+  +  P   G P  LP   +Q        N P  + ++ +S  T+    P 
Sbjct: 527 AHPYAMSPSLGSLRPYPPG-PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPC 585

Query: 345 SQPGMAPSQPGAYQPRP-----------------GFTSLPGSTMTPPPSGPNPYARNRPP 387
           S P  +    GA  P P                    S P    T  P GP PY +  P 
Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645

Query: 388 FGQGYTQPGPGYR 400
            G   T   PGY+
Sbjct: 646 PGAYKTATPPGYK 658



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/223 (23%), Positives = 78/223 (34%), Gaps = 36/223 (16%)

Query: 192 VSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQA 251
           V GP          TP S++SS ++  PP   P  P           + G         A
Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTP-----------VGGGNLPSAPPPA 292

Query: 252 GYGAQQPQAPPQQPQQYGIQYSASYSQQTG--------PQQPQQFQGYGQQPTSQAPAPA 303
            +    P  PP  P    +  +++     G        P      QG G  P      P 
Sbjct: 293 NFPHVTPNLPP-PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351

Query: 304 FSGQPQQLP------AQPPQQYQASNYPAQTYTAQTSQPTNYTVA---PASQPGMAPSQP 354
            +  P  LP        PP ++  S+  + +  A +S  ++ + A   PASQ    PS P
Sbjct: 352 LAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ--ALPSYP 409

Query: 355 GAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
            ++ P    TSL  S    PP    P   ++  + QG   P P
Sbjct: 410 HSFPPP---TSL--SVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 45/194 (23%), Positives = 64/194 (32%), Gaps = 36/194 (18%)

Query: 193 SGPPSAPAEDRSGTPDSIASSS-SAAHPPGVQPQQ------PPYTGAQTQAGQIEGQMYQ 245
           +GP   P    S +  S +  S   +HP   Q  Q      PP     T +  +   +  
Sbjct: 561 AGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIAT 620

Query: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTG------PQQPQQFQ-----GY-GQ 293
                AGY    P  PP     YG +  +  + +T       P  P  F+     GY G 
Sbjct: 621 VASSPAGYKTASPPGPPP----YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT 676

Query: 294 QPTSQ-----------APAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVA 342
            P +             P P     P  LP+ PP     ++ P  + T    +P      
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736

Query: 343 PAS--QPGMAPSQP 354
           P S   P  +PS P
Sbjct: 737 PESPVPPARSPSPP 750



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 33/143 (23%), Positives = 54/143 (37%), Gaps = 22/143 (15%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP  P   R+ +P +  +++    PPG +P  PP     T  G      Y+     AG 
Sbjct: 635 GPP--PYGKRAPSPGAYKTAT----PPGYKPGSPPSFRTGTPPG------YRGTSPPAGP 682

Query: 254 GAQQPQAP--------PQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS 305
           G  +P +P        P  P           +  +GP  P       Q+P  +   P   
Sbjct: 683 GTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP--PLSATQIKQEPAEEYETPESP 740

Query: 306 GQPQQLPAQPPQQYQASNYPAQT 328
             P + P+ PP+     ++ +Q+
Sbjct: 741 VPPARSPSPPPKVVDVPSHASQS 763


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 77/313 (24%), Positives = 103/313 (32%), Gaps = 62/313 (19%)

Query: 129 PGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMS------AFDP---LKNQDEINK 179
           P P    P + +       S+S SS   S     AS +      +F P   L   ++  K
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPK 426

Query: 180 NVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQI 239
               +         GPP  P   R         ++S AHP       PP TGAQ+ A   
Sbjct: 427 YTQPSLPSQAVWSQGPPPPPPYGR-------LLANSNAHPGPF----PPSTGAQSTAHPP 475

Query: 240 EGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQF----------- 288
               +  +QQQ     QQ Q   QQ Q +G          +GP  P  F           
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHG---------NSGPPPPGAFPHPLEGGSSHH 526

Query: 289 -QGYGQQPTSQAPAPAFSGQPQQLP---AQPPQQYQASNYPAQTYTAQTSQPTNYTVAPA 344
              Y   P+  +  P   G P  LP   +Q        N P  + ++ +S  T+    P 
Sbjct: 527 AHPYAMSPSLGSLRPYPPG-PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPC 585

Query: 345 SQPGMAPSQPGAYQPRP-----------------GFTSLPGSTMTPPPSGPNPYARNRPP 387
           S P  +    GA  P P                    S P    T  P GP PY +  P 
Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645

Query: 388 FGQGYTQPGPGYR 400
            G   T   PGY+
Sbjct: 646 PGAYKTATPPGYK 658



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 53/223 (23%), Positives = 78/223 (34%), Gaps = 36/223 (16%)

Query: 192 VSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQA 251
           V GP          TP S++SS ++  PP   P  P           + G         A
Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTP-----------VGGGNLPSAPPPA 292

Query: 252 GYGAQQPQAPPQQPQQYGIQYSASYSQQTG--------PQQPQQFQGYGQQPTSQAPAPA 303
            +    P  PP  P    +  +++     G        P      QG G  P      P 
Sbjct: 293 NFPHVTPNLPP-PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351

Query: 304 FSGQPQQLP------AQPPQQYQASNYPAQTYTAQTSQPTNYTVA---PASQPGMAPSQP 354
            +  P  LP        PP ++  S+  + +  A +S  ++ + A   PASQ    PS P
Sbjct: 352 LAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ--ALPSYP 409

Query: 355 GAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
            ++ P    TSL  S    PP    P   ++  + QG   P P
Sbjct: 410 HSFPPP---TSL--SVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 45/194 (23%), Positives = 64/194 (32%), Gaps = 36/194 (18%)

Query: 193 SGPPSAPAEDRSGTPDSIASSS-SAAHPPGVQPQQ------PPYTGAQTQAGQIEGQMYQ 245
           +GP   P    S +  S +  S   +HP   Q  Q      PP     T +  +   +  
Sbjct: 561 AGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIAT 620

Query: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTG------PQQPQQFQ-----GY-GQ 293
                AGY    P  PP     YG +  +  + +T       P  P  F+     GY G 
Sbjct: 621 VASSPAGYKTASPPGPPP----YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT 676

Query: 294 QPTSQ-----------APAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVA 342
            P +             P P     P  LP+ PP     ++ P  + T    +P      
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736

Query: 343 PAS--QPGMAPSQP 354
           P S   P  +PS P
Sbjct: 737 PESPVPPARSPSPP 750



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 33/143 (23%), Positives = 54/143 (37%), Gaps = 22/143 (15%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP  P   R+ +P +  +++    PPG +P  PP     T  G      Y+     AG 
Sbjct: 635 GPP--PYGKRAPSPGAYKTAT----PPGYKPGSPPSFRTGTPPG------YRGTSPPAGP 682

Query: 254 GAQQPQAP--------PQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS 305
           G  +P +P        P  P           +  +GP  P       Q+P  +   P   
Sbjct: 683 GTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP--PLSATQIKQEPAEEYETPESP 740

Query: 306 GQPQQLPAQPPQQYQASNYPAQT 328
             P + P+ PP+     ++ +Q+
Sbjct: 741 VPPARSPSPPPKVVDVPSHASQS 763


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 54/208 (25%), Positives = 71/208 (34%), Gaps = 22/208 (10%)

Query: 190 DQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQ 249
           +Q   PP  P + +   P     S     PPG    +PP  G Q+Q              
Sbjct: 45  NQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPP----------- 93

Query: 250 QAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQ 309
                   P  P + P Q G Q   +      P++P   QG G Q     P P   G+P+
Sbjct: 94  ------PHPGKPERPPPQGGNQSQGTPPPPGKPERPPP-QG-GNQSHRPPPPP---GKPE 142

Query: 310 QLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGS 369
           + P Q   Q Q              Q  N + +  S PG     P     +P     PG 
Sbjct: 143 RPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGK 202

Query: 370 TMTPPPSGPNPYARNRPPFGQGYTQPGP 397
              PPP+G NP     PP G+    P P
Sbjct: 203 PQGPPPAGGNPQQPQAPPAGKPQGPPPP 230



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/121 (31%), Positives = 47/121 (38%), Gaps = 7/121 (5%)

Query: 280 TGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNY 339
           +G  + ++ QG G QP    P P   G+PQ  P Q   Q Q    P      +  Q  N 
Sbjct: 33  SGKPEGRRPQG-GNQPQRPPPPP---GKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQ 88

Query: 340 TVAPASQPGMAPSQP--GAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
           +  P   PG     P  G  Q + G    PG    PPP G N   R  PP G+    P  
Sbjct: 89  SQGPPPHPGKPERPPPQGGNQSQ-GTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQ 147

Query: 398 G 398
           G
Sbjct: 148 G 148



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 42/146 (28%), Positives = 54/146 (36%), Gaps = 17/146 (11%)

Query: 190 DQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQA-----GQIEGQMY 244
           +Q  G P  P +     P     S     PPG   + PP  G Q+Q      G+ EG   
Sbjct: 108 NQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPP 167

Query: 245 QQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAF 304
           Q+  +     A+ P   PQ P Q              PQ P    G  QQP  QAP    
Sbjct: 168 QEGNKSRS--ARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQP--QAPP--- 220

Query: 305 SGQPQQLP-----AQPPQQYQASNYP 325
           +G+PQ  P      +PP+  Q    P
Sbjct: 221 AGKPQGPPPPPQGGRPPRPAQGQQPP 246


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 69/263 (26%), Positives = 98/263 (37%), Gaps = 27/263 (10%)

Query: 159 QVMAASMSAFDPLKNQD-----EINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASS 213
           +V+ +SM      +++D     E+  N M+       Q    P   +  ++ +P ++   
Sbjct: 386 EVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLG 445

Query: 214 SSAAHPPGVQP--QQPPYTGAQTQAG---QIEGQMYQQY---QQQAGYGAQQPQAPPQQP 265
              +  P   P  Q+PP  G   Q G   Q +G   QQ    Q Q       P A    P
Sbjct: 446 RQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLP 505

Query: 266 QQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYP 325
           Q+     SA     +    P Q QG   +P +  P    + +P   PA P  Q QA    
Sbjct: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARP---PASPSPQRQAGPPQ 562

Query: 326 A--QTYTAQTSQPTNYTVAPASQPGMAPSQ--PG-------AYQPRPGFTSLPGSTMTPP 374
           A  QT  +  + P      P  Q    P Q  PG       A Q  P   + P +T  P 
Sbjct: 563 ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPR 622

Query: 375 PSGPNPYARNRPPFGQGYTQPGP 397
           PSGP P  R +P   Q  +Q  P
Sbjct: 623 PSGPGPAGRPKPQLAQKPSQDVP 645



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 48/151 (31%), Positives = 59/151 (39%), Gaps = 10/151 (6%)

Query: 255 AQQPQAPPQQ---PQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQL 311
           +QQP  PP Q   P Q G        Q+ GP   Q+    GQQ  S    PA S  PQ+L
Sbjct: 449 SQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRL 508

Query: 312 PAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTM 371
           P+      Q ++  A     Q  Q       P + P   P    + Q + G    P +T 
Sbjct: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAG---PPQATR 565

Query: 372 TPPPSGP-NPYARNRPPFG---QGYTQPGPG 398
               SGP  P A   PP G   QG  Q  PG
Sbjct: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 57/217 (26%), Positives = 74/217 (34%), Gaps = 51/217 (23%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP+      S  P  + S +SA       PQQP    A   A   +GQ  Q      G 
Sbjct: 497 GPPAG-----SPLPQRLPSPTSA-------PQQP----ASQAAPPTQGQGRQSRPVAGGP 540

Query: 254 GAQQPQAPPQQPQQYGIQYSASYSQQTGPQQP-QQFQGYGQQPTSQAPAPAFSGQPQQLP 312
           GA     PP  P         S  +Q GP Q  +Q    G  P   + AP    Q Q  P
Sbjct: 541 GAPPAARPPASP---------SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591

Query: 313 AQPP------QQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPG-AYQPRPGFTS 365
            +PP      +Q   +    +T    T QP              PS PG A +P+P    
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQP-------------RPSGPGPAGRPKPQLAQ 638

Query: 366 LPGSTMTPPPSG-----PNPYARNRPPFGQGYTQPGP 397
            P   + PP +      P+P           +  P P
Sbjct: 639 KPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEP 675


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 69/263 (26%), Positives = 98/263 (37%), Gaps = 27/263 (10%)

Query: 159 QVMAASMSAFDPLKNQD-----EINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASS 213
           +V+ +SM      +++D     E+  N M+       Q    P   +  ++ +P ++   
Sbjct: 386 EVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLG 445

Query: 214 SSAAHPPGVQP--QQPPYTGAQTQAG---QIEGQMYQQY---QQQAGYGAQQPQAPPQQP 265
              +  P   P  Q+PP  G   Q G   Q +G   QQ    Q Q       P A    P
Sbjct: 446 RQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLP 505

Query: 266 QQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYP 325
           Q+     SA     +    P Q QG   +P +  P    + +P   PA P  Q QA    
Sbjct: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARP---PASPSPQRQAGPPQ 562

Query: 326 A--QTYTAQTSQPTNYTVAPASQPGMAPSQ--PG-------AYQPRPGFTSLPGSTMTPP 374
           A  QT  +  + P      P  Q    P Q  PG       A Q  P   + P +T  P 
Sbjct: 563 ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPR 622

Query: 375 PSGPNPYARNRPPFGQGYTQPGP 397
           PSGP P  R +P   Q  +Q  P
Sbjct: 623 PSGPGPAGRPKPQLAQKPSQDVP 645



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 48/151 (31%), Positives = 59/151 (39%), Gaps = 10/151 (6%)

Query: 255 AQQPQAPPQQ---PQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQL 311
           +QQP  PP Q   P Q G        Q+ GP   Q+    GQQ  S    PA S  PQ+L
Sbjct: 449 SQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRL 508

Query: 312 PAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTM 371
           P+      Q ++  A     Q  Q       P + P   P    + Q + G    P +T 
Sbjct: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAG---PPQATR 565

Query: 372 TPPPSGP-NPYARNRPPFG---QGYTQPGPG 398
               SGP  P A   PP G   QG  Q  PG
Sbjct: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 57/210 (27%), Positives = 74/210 (35%), Gaps = 51/210 (24%)

Query: 194 GPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGY 253
           GPP+      S  P  + S +SA       PQQP    A   A   +GQ  Q      G 
Sbjct: 497 GPPAG-----SPLPQRLPSPTSA-------PQQP----ASQAAPPTQGQGRQSRPVAGGP 540

Query: 254 GAQQPQAPPQQPQQYGIQYSASYSQQTGPQQP-QQFQGYGQQPTSQAPAPAFSGQPQQLP 312
           GA     PP  P         S  +Q GP Q  +Q    G  P   + AP    Q Q  P
Sbjct: 541 GAPPAARPPASP---------SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591

Query: 313 AQPP------QQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPG-AYQPRPGFTS 365
            +PP      +Q   +    +T    T QP              PS PG A +P+P    
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQP-------------RPSGPGPAGRPKPQLAQ 638

Query: 366 LPGSTMTPPPSG-----PNPYARNRPPFGQ 390
            P   + PP +      P+P  +  P   Q
Sbjct: 639 KPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 79/279 (28%), Positives = 101/279 (36%), Gaps = 45/279 (16%)

Query: 145 EEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFG------------------ 186
           +EK  S S G+Q+    ++ M        Q ++  N M   G                  
Sbjct: 477 QEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQD 536

Query: 187 LTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHP--PGVQPQQ-PPYTGAQTQAGQIEGQM 243
           L+   ++ P  A    +  T      +S  A+   P V P Q  P     TQ  Q + Q 
Sbjct: 537 LSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ 596

Query: 244 YQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPA 303
            QQ QQQ     QQ Q   QQ QQ   Q  +S S Q   QQ QQ      Q   Q     
Sbjct: 597 QQQQQQQ-----QQQQQQQQQQQQQQQQQQSSISAQ---QQQQQQSSISAQQQQQQQQQQ 648

Query: 304 FSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAP----------ASQPGMAPSQ 353
              Q QQ   Q  QQ Q S+ PAQ+     SQP   +  P           +QP      
Sbjct: 649 QQQQQQQQQQQQQQQQQPSSQPAQSL---PSQPLLRSPLPLQQKLLLQQMQNQPIAGMGY 705

Query: 354 PGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGY 392
             + Q R    S+ G    P PS PNP   + P  G GY
Sbjct: 706 QVSQQQRQDQHSVVGQNTGPSPS-PNPC--SNPNTGSGY 741



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 35/141 (24%), Positives = 51/141 (36%), Gaps = 18/141 (12%)

Query: 212 SSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQ--PQAPPQQPQQYG 269
           S S    PP   P       A + +  I      Q Q Q G GA +  P        Q  
Sbjct: 377 SGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQL 436

Query: 270 IQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTY 329
            Q +A+  Q    QQ QQ      QPT+ +  P+ +G         P  +     P+ ++
Sbjct: 437 KQIAANRQQHARMQQHQQ----QHQPTNWSALPSSAG-------PSPGPFGQEKIPSPSF 485

Query: 330 TAQTSQPTNYTVAPASQPGMA 350
             QT  P +     +  PG+A
Sbjct: 486 GQQTFSPQS-----SPMPGVA 501


>gi|162951884 R3H domain containing 2 [Homo sapiens]
          Length = 976

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 62/232 (26%), Positives = 81/232 (34%), Gaps = 46/232 (19%)

Query: 204 SGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIE------------GQMYQQYQQQA 251
           +G P   ++ S+++H P  Q   PP  G      QI+             Q Y+      
Sbjct: 482 TGQPLPTSNYSTSSHAPPTQQVLPPQ-GYMQPPQQIQVSYYPPGQYPNSNQQYRPLSHPV 540

Query: 252 GYGAQQPQAPPQQPQQYGI------QYSASYSQQTGPQQPQ--------------QFQG- 290
            Y  Q+ Q  PQ  QQ G+      Q  A+Y    G QQPQ              Q QG 
Sbjct: 541 AYSPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGL 600

Query: 291 ---YGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQP 347
              Y   P+ Q P  + S    Q P Q P     S    Q        P  Y++ P    
Sbjct: 601 VVQYTPLPSYQVPVGSDSQNVVQPPFQQPMLVPVSQ-SVQGGLPAAGVPVYYSMIP---- 655

Query: 348 GMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYA-RNRPPFGQGYTQPGPG 398
              P+Q     P  GF   PGS     P  P+P +    P    G +  GPG
Sbjct: 656 ---PAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMPQQYSGVSPSGPG 704



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 59/227 (25%), Positives = 76/227 (33%), Gaps = 63/227 (27%)

Query: 195 PPSAPAEDRSGTP-----DSIASSSSAA----HPPGVQPQQPPYTGAQTQAGQIEGQMYQ 245
           PP   A   SG       DSI SS   +      PG+    P      T +  + G +  
Sbjct: 342 PPVTKASSFSGISILTRGDSIGSSKGGSAGRISRPGMALGAPEVCNQVTSSQSVRGLLPC 401

Query: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAP--- 302
             QQQ     QQ  A P  PQQ     +   SQ      P       +Q +++A  P   
Sbjct: 402 TAQQQQQQQQQQLPALPPTPQQQPPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSAA 461

Query: 303 ------------------AFSGQP----------------QQLP----AQPPQQYQASNY 324
                             A +GQP                Q LP     QPPQQ Q S Y
Sbjct: 462 LFQTPLISQHPQQTSFIMASTGQPLPTSNYSTSSHAPPTQQVLPPQGYMQPPQQIQVSYY 521

Query: 325 PAQTY--TAQTSQPTNYTVA-----------PASQPGMAPSQPGAYQ 358
           P   Y  + Q  +P ++ VA           P+ QPG+ P  P   Q
Sbjct: 522 PPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQ 568


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 74/257 (28%), Positives = 86/257 (33%), Gaps = 36/257 (14%)

Query: 172 KNQDEINKNVMSAFGLTDDQVSG------PPSAPAEDRSGTPDSIAS----SSSAAHPPG 221
           K+Q  ++  + +   LT    +G      PP  P +   G     A     S S   PPG
Sbjct: 73  KSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG 132

Query: 222 VQPQQP----------PYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQ 271
                P          P T  Q Q   ++ Q  QQ  QQ    A Q Q   QQ QQ+  Q
Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ 192

Query: 272 YSASYSQ-QTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQ-------ASN 323
            SA   Q Q   QQ QQ Q   QQ   Q        Q QQ   Q  QQ Q          
Sbjct: 193 QSAMQQQFQAVVQQQQQLQ---QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ 249

Query: 324 YPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGST---MTPPPSGPNP 380
              Q    Q  Q       P  QP M   QP   Q  P        T     PP     P
Sbjct: 250 QQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309

Query: 381 YARNRPPF--GQGYTQP 395
            A+N+P     Q  TQP
Sbjct: 310 VAQNQPSQLPPQSQTQP 326



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 53/159 (33%), Positives = 60/159 (37%), Gaps = 17/159 (10%)

Query: 223 QPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGP 282
           Q QQ     AQ Q  Q + Q  QQ QQQ    A Q Q P QQP    +Q       Q  P
Sbjct: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQ--ALQAQPPIQQPP---MQQPQPPPSQALP 287

Query: 283 QQPQQFQ--GYGQQPTSQAPAPAFSGQPQQLPAQ---PPQQYQASNYPAQTYTAQTSQPT 337
           QQ QQ     + Q P      P    QP QLP Q    P   QA   P Q     T  P 
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQ--MLYTQPPL 345

Query: 338 NYTVAP--ASQPGMAPSQPGAYQPRPGFTSLPGSTMTPP 374
            +  AP    QP   P QP   Q +    +   + M  P
Sbjct: 346 KFVRAPMVVQQP---PVQPQVQQQQTAVQTAQAAQMVAP 381



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 61/234 (26%), Positives = 86/234 (36%), Gaps = 27/234 (11%)

Query: 172 KNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTG 231
           +NQ +I +       +   Q+        + +     ++ +      PP  QPQ PP   
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP--- 282

Query: 232 AQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGP--QQPQQFQ 289
           +Q    Q++ QM+     Q     QQP     QP Q   Q       QT P   Q Q   
Sbjct: 283 SQALPQQLQ-QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ------SQTQPLVSQAQALP 335

Query: 290 G---YGQQPTSQAPAPAFSGQPQQLPAQPP-QQYQASNYPAQTYTAQTSQPTNYTVAPA- 344
           G   Y Q P     AP    QP   P QP  QQ Q +   AQ   AQ   P    +  A 
Sbjct: 336 GQMLYTQPPLKFVRAPMVVQQP---PVQPQVQQQQTAVQTAQ--AAQMVAPGVQMITEAL 390

Query: 345 SQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPG 398
           +Q GM       + P    +++P S++   P G  P A+         + P PG
Sbjct: 391 AQGGM--HIRARFPPTTAVSAIPSSSI---PLGRQPMAQVSQSSLPMLSSPSPG 439



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 58/228 (25%), Positives = 79/228 (34%), Gaps = 71/228 (31%)

Query: 218 HPPGVQPQQPPYTGAQ--------------TQAGQIEGQMYQQYQQ------QAGYGAQQ 257
           H P  QPQQPP    Q              +QA  + GQM   Y Q      +A    QQ
Sbjct: 299 HQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQML--YTQPPLKFVRAPMVVQQ 356

Query: 258 PQAPPQQPQQYGIQYSASYSQQTGPQQ---------------------------PQQFQG 290
           P   PQ  QQ     +A  +Q   P                             P     
Sbjct: 357 PPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIP 416

Query: 291 YGQQPTSQ----------APAPAFSGQ-PQQLPAQP---PQQYQASNYP-AQTYTAQTSQ 335
            G+QP +Q          +P+P    Q PQ +P  P   PQ  Q S+ P +   +     
Sbjct: 417 LGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPS 476

Query: 336 PTNYTVAPASQPGMAPSQPGAYQ----PRPGFTSL---PGSTMTPPPS 376
           P+++  +P+ QP  +P      Q    P PG  +    P S M+P  S
Sbjct: 477 PSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 524


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 74/257 (28%), Positives = 86/257 (33%), Gaps = 36/257 (14%)

Query: 172 KNQDEINKNVMSAFGLTDDQVSG------PPSAPAEDRSGTPDSIAS----SSSAAHPPG 221
           K+Q  ++  + +   LT    +G      PP  P +   G     A     S S   PPG
Sbjct: 73  KSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG 132

Query: 222 VQPQQP----------PYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQ 271
                P          P T  Q Q   ++ Q  QQ  QQ    A Q Q   QQ QQ+  Q
Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ 192

Query: 272 YSASYSQ-QTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQ-------ASN 323
            SA   Q Q   QQ QQ Q   QQ   Q        Q QQ   Q  QQ Q          
Sbjct: 193 QSAMQQQFQAVVQQQQQLQ---QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQ 249

Query: 324 YPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGST---MTPPPSGPNP 380
              Q    Q  Q       P  QP M   QP   Q  P        T     PP     P
Sbjct: 250 QQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309

Query: 381 YARNRPPF--GQGYTQP 395
            A+N+P     Q  TQP
Sbjct: 310 VAQNQPSQLPPQSQTQP 326



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 61/232 (26%), Positives = 81/232 (34%), Gaps = 28/232 (12%)

Query: 172 KNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTG 231
           +NQ +I +       +   Q+        + +     ++ +      PP  QPQ PP   
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP--- 282

Query: 232 AQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGP--QQPQQFQ 289
           +Q    Q++ QM+     Q     QQP     QP Q   Q       QT P   Q Q   
Sbjct: 283 SQALPQQLQ-QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ------SQTQPLVSQAQALP 335

Query: 290 G---YGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQ 346
           G   Y Q P     AP        +  QPP Q Q         TAQ +Q     VAP  Q
Sbjct: 336 GQMLYTQPPLKFVRAP-------MVVQQPPVQPQVQQQQTAVQTAQAAQ----MVAPGVQ 384

Query: 347 PGMAPSQPGAYQPRPGFTSLPGSTMTPPPS-GPNPYARNRPPFGQGYTQPGP 397
              + S P    P PG       +M PPP   P P   +  P     + P P
Sbjct: 385 VSQS-SLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAP 435



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 52/186 (27%), Positives = 71/186 (38%), Gaps = 27/186 (14%)

Query: 218 HPPGVQPQQPPYTGAQ--------------TQAGQIEGQM-YQQYQQQAGYGAQQPQAPP 262
           H P  QPQQPP    Q              +QA  + GQM Y Q   +        Q PP
Sbjct: 299 HQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPP 358

Query: 263 QQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQ-PQQLPAQP---PQQ 318
            QPQ    Q +   +Q      P         P   +P+P    Q PQ +P  P   PQ 
Sbjct: 359 VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 418

Query: 319 YQASNYP-AQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQ----PRPGFTSL---PGST 370
            Q S+ P +   +     P+++  +P+ QP  +P      Q    P PG  +    P S 
Sbjct: 419 GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSV 478

Query: 371 MTPPPS 376
           M+P  S
Sbjct: 479 MSPAGS 484


>gi|5454064 RNA binding motif protein 14 [Homo sapiens]
          Length = 669

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 55/187 (29%), Positives = 75/187 (40%), Gaps = 14/187 (7%)

Query: 198 APAEDRSGTPDSIASSSSAAHP-PGVQPQQPPYT--GAQTQAGQIEGQMYQQYQQQAGYG 254
           AP   +  +P S ++++S+  P  G QP     +  G Q  A         Q    A YG
Sbjct: 283 APYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYG 342

Query: 255 AQQPQAPPQQPQQYGIQYSASYSQQTGPQQP-----QQFQGYGQQPTSQAPAPAFSGQPQ 309
            Q      Q    YG++ +AS     G          Q   YG Q  S A + A+  Q  
Sbjct: 343 NQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQ--SAASSLAYGAQAA 400

Query: 310 QLPAQPPQQY--QASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLP 367
              AQP   Y  Q++ Y AQ   + +SQP  Y   PA+    A SQP AY  +   T + 
Sbjct: 401 SYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYA-SQPAAYAAQ-ATTPMA 458

Query: 368 GSTMTPP 374
           GS    P
Sbjct: 459 GSYGAQP 465



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 43/141 (30%), Positives = 58/141 (41%), Gaps = 20/141 (14%)

Query: 249 QQAGYGAQQPQ---APPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTS----QAPA 301
           Q A YGAQ      A   Q   Y  Q SASY+ Q+ P   QQ   Y  QP +     A A
Sbjct: 380 QAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATA 439

Query: 302 PAFSGQPQQLPAQPPQQYQASNYPAQ--------TYTAQTSQPTNYTVAPASQPGMAPSQ 353
            A++ QP    AQ      A +Y AQ        +Y AQ S   + +    S    A + 
Sbjct: 440 AAYASQPAAYAAQATTP-MAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQS----AAAA 494

Query: 354 PGAYQPRPGFTSLPGSTMTPP 374
            G+Y     + + P +T+  P
Sbjct: 495 TGSYGAAAAYGAQPSATLAAP 515



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 61/207 (29%), Positives = 76/207 (36%), Gaps = 19/207 (9%)

Query: 184 AFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQM 243
           A+G      +  PSA    +S  P +   ++S +  P     QP    A   A Q     
Sbjct: 394 AYGAQAASYNAQPSASYNAQSA-PYAAQQAASYSSQPAAYVAQPATAAAY--ASQPAAYA 450

Query: 244 YQQYQQQAG-YGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAP 302
            Q     AG YGAQ       Q   YG Q S   S   G Q      G      S   A 
Sbjct: 451 AQATTPMAGSYGAQP--VVQTQLNSYGAQASMGLSGSYGAQSAAAATG------SYGAAA 502

Query: 303 AFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPG 362
           A+  QP    A P  + Q+S   A +Y AQ  Q      +   QPG A    GA QP   
Sbjct: 503 AYGAQPSATLAAP-YRTQSSASLAASYAAQ--QHPQAAASYRGQPGNA--YDGAGQPSAA 557

Query: 363 FTSLPGSTMTPPPSGPNPYARNR--PP 387
           + S+    +    S P PY R R  PP
Sbjct: 558 YLSMSQGAVANANSTPPPYERTRLSPP 584


>gi|57165375 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 44/132 (33%), Positives = 49/132 (37%), Gaps = 10/132 (7%)

Query: 218 HPPGVQPQ-----QPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQY 272
           +P G QP      QPPY GA       +   Y Q     G         PQ P   G   
Sbjct: 21  YPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYP 80

Query: 273 SASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS-GQPQQLPAQPPQQYQASNY----PAQ 327
              Y Q+  PQ P    GY Q P  Q+P P    GQPQ  P Q P   Q  NY    P  
Sbjct: 81  QGPYPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPPS 140

Query: 328 TYTAQTSQPTNY 339
            Y  Q    TN+
Sbjct: 141 YYDNQDFPATNW 152



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 334 SQPTNYTVAPASQPGMAPSQPGAYQP-RPGFTS--LPGSTMTPPPSGPNPYARNRPPFG- 389
           S   ++ V+  + P   P  PG  QP  P +     PG+    PP  P+PY +   P G 
Sbjct: 2   SHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGP 61

Query: 390 ----QGYTQPGP 397
               QG    GP
Sbjct: 62  SPYPQGGYPQGP 73


>gi|57165373 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 44/132 (33%), Positives = 49/132 (37%), Gaps = 10/132 (7%)

Query: 218 HPPGVQPQ-----QPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQY 272
           +P G QP      QPPY GA       +   Y Q     G         PQ P   G   
Sbjct: 21  YPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYP 80

Query: 273 SASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS-GQPQQLPAQPPQQYQASNY----PAQ 327
              Y Q+  PQ P    GY Q P  Q+P P    GQPQ  P Q P   Q  NY    P  
Sbjct: 81  QGPYPQEGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPPS 140

Query: 328 TYTAQTSQPTNY 339
            Y  Q    TN+
Sbjct: 141 YYDNQDFPATNW 152



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 334 SQPTNYTVAPASQPGMAPSQPGAYQP-RPGFTS--LPGSTMTPPPSGPNPYARNRPPFG- 389
           S   ++ V+  + P   P  PG  QP  P +     PG+    PP  P+PY +   P G 
Sbjct: 2   SHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGP 61

Query: 390 ----QGYTQPGP 397
               QG    GP
Sbjct: 62  SPYPQGGYPQGP 73


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 64/201 (31%), Positives = 71/201 (35%), Gaps = 23/201 (11%)

Query: 195 PPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYG 254
           PPS P       P + A    A  PP   PQQ P T AQ    Q +     Q Q      
Sbjct: 423 PPSQPL------PQTQAKQPQA--PP--TPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQ 472

Query: 255 AQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPT-SQAPAPAFSGQPQQLPA 313
            QQ Q PP Q Q  G  Y     QQ   QQ Q      QQP  +Q P  +  G  QQL  
Sbjct: 473 QQQQQPPPAQQQPAGTFYQ---QQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQ 529

Query: 314 ---QPPQQYQASNYPAQTYTA-QTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGS 369
              Q  QQ Q      Q  TA    Q      A   +P MA  Q    QP+P     P  
Sbjct: 530 NFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQP--QPQPAAAPQPAP 587

Query: 370 TMTPPPSGP---NPYARNRPP 387
              P    P    P  +  PP
Sbjct: 588 AQEPAIQAPVRQQPKVQTTPP 608



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/201 (28%), Positives = 71/201 (35%), Gaps = 21/201 (10%)

Query: 169 DPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPP 228
           +P+K  +   K       LTD         P  + S  P     +      PG+ P QP 
Sbjct: 335 EPVKASEAAAKKTQPKARLTDP-------IPTTETSIAPRQRPKAGQTQPNPGILPIQPA 387

Query: 229 YTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQT--GPQQPQ 286
            T  +    Q   Q       Q G  A  PQ  PQ P    +  + +   Q    PQQ  
Sbjct: 388 LTPRKRATVQPPPQAAGS-SNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTP 446

Query: 287 QFQGYG----QQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVA 342
             Q  G     Q T Q     F  Q QQ    PP Q Q +    Q   AQT Q     V 
Sbjct: 447 STQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQ--FQAVH 504

Query: 343 PAS-QPGMAP----SQPGAYQ 358
           PA+ QP +A     SQ G+ Q
Sbjct: 505 PATQQPAIAQFPVVSQGGSQQ 525



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 298 QAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYT--AQTSQP---TNYTVAPASQP--GMA 350
           + P P     P  +PA+ P+  +AS   A+     A+ + P   T  ++AP  +P  G  
Sbjct: 318 ECPIPNVQNSP--IPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQT 375

Query: 351 PSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
              PG    +P  T    +T+ PPP      + N+P       QP P
Sbjct: 376 QPNPGILPIQPALTPRKRATVQPPPQAAG--SSNQPGLLASVPQPKP 420


>gi|124378039 SEC16 homolog A [Homo sapiens]
          Length = 2357

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 77/308 (25%), Positives = 118/308 (38%), Gaps = 48/308 (15%)

Query: 123  LEPPGEPGPSTNIPENDTVDGREEKS-------ASDSSGKQSTQVMAASMSAFDPLKNQD 175
            ++PP +P P   +PE+     ++ K+       A+  +G  S  ++  +     P  N+ 
Sbjct: 926  VQPPSQPVPENLVPESQ----KDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKA 981

Query: 176  EINKNVMSAFGLTDDQVSGPPSAPAEDRSGT-PDSIASSSS-AAHPPGVQPQQPPYTGAQ 233
              + +    +G  D  +S     P    + +  DS+AS  S A+HP    P  P      
Sbjct: 982  NHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFY 1041

Query: 234  TQAGQ-IEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQ-PQQFQGY 291
             Q  +  +GQ   +  QQ     QQ  +PPQ P+       A +S+ + P+  P Q Q  
Sbjct: 1042 QQVTKDAQGQPGLERAQQELVPPQQQASPPQLPK-------AMFSELSNPESLPAQGQA- 1093

Query: 292  GQQPTSQAPAP-AFSGQPQQLPAQPPQQYQASNYPAQTYTA--QTSQPTNYTVAPASQPG 348
              Q ++Q+PA        QQLP +PPQ    S   + +  A   + QP    V PA  PG
Sbjct: 1094 --QNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPV-PALAPG 1150

Query: 349  MAPSQPGA-YQPRPGFTSLPGSTMTPPPSGP------------------NPYARNRPPFG 389
              P    A Y  RP + +       P P  P                   PY      + 
Sbjct: 1151 PPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYA 1210

Query: 390  QGYTQPGP 397
            Q Y  P P
Sbjct: 1211 QNYRYPEP 1218



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 42/189 (22%), Positives = 67/189 (35%), Gaps = 14/189 (7%)

Query: 200 AEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQP- 258
           A  R     +   SSS + PP +Q   P   G     G +    + +   Q   G  +P 
Sbjct: 56  AFSRQALQSTPLGSSSKSSPPVLQGPAP--AGFSQHPGLLVPHTHARDSSQ---GPCEPL 110

Query: 259 QAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQ 318
             P  QP+ +   +S + +  + P  P+  +     P+S+         P  +P   P+ 
Sbjct: 111 PGPLTQPRAHASPFSGALTP-SAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPET 169

Query: 319 ----YQASNYPAQTYTAQTSQPTNYTVAPASQPGMAP---SQPGAYQPRPGFTSLPGSTM 371
               +   N P          P +  V PA+ P +       PG + P  G     G   
Sbjct: 170 SHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHR 229

Query: 372 TPPPSGPNP 380
           +P P GP P
Sbjct: 230 SPCPEGPVP 238



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 55/261 (21%), Positives = 87/261 (33%), Gaps = 63/261 (24%)

Query: 128 EPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGL 187
           +P P    P  + + G++ ++ S ++  QS   + AS                       
Sbjct: 752 KPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGAS----------------------- 788

Query: 188 TDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQY 247
             + +  PP    E+   +  S   +S  + PP    Q PP   AQ              
Sbjct: 789 --ENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHS---------- 836

Query: 248 QQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPA------ 301
                Y   QP           I +S S S      Q  +    G +P   + A      
Sbjct: 837 -----YNLAQP-----------INFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSG 880

Query: 302 --PAFSGQPQQ--LPAQPPQQYQASNYPAQTYTAQ--TSQPTNYTVAPASQPGMAPSQPG 355
              + SG P    L    P     SN+P  +  ++  ++QP N  V P SQP      P 
Sbjct: 881 ENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPE 940

Query: 356 AYQPRPGFTSLPGSTMTPPPS 376
           + + R   ++LPG   +P  S
Sbjct: 941 SQKDRKAGSALPGFANSPAGS 961



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 45/217 (20%), Positives = 75/217 (34%), Gaps = 36/217 (16%)

Query: 206  TPDSIASSSSAAHPPGVQ-----PQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGA----- 255
            TP      S A  PPG       P QPP + +     +  GQ  ++  ++   G      
Sbjct: 2054 TPSRTVPDSEA--PPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFR 2111

Query: 256  -----QQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQ 310
                 ++ +A     +   I +    +Q     +P++          +AP P  +  P+ 
Sbjct: 2112 WLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEE--------EKKAPPPPPTSMPKT 2163

Query: 311  LPAQPPQQYQASNYPAQTYT-------AQTSQPTNYTVAPASQPGMAPSQ---PGAYQPR 360
            + A PP        P   Y+       A+     N +    S+P +AP+    P A  P 
Sbjct: 2164 VQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPI 2223

Query: 361  PGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGP 397
            P    +P +     P  P+   R  P   +G   P P
Sbjct: 2224 PSNLFVP-TPDAEEPQLPDGTGREGPAAARGLANPEP 2259


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 75/304 (24%)

Query: 126 PGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAF 185
           PG PGP+          GR + S  D    +  Q+     +   P     + +     ++
Sbjct: 445 PGTPGPTM---------GRSQGSPMDPMVMKRPQLYGMGSN---PHSQPQQSSPYPGGSY 492

Query: 186 GLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQ 245
           G       GP   P   +  TP ++A      +P   Q Q PP  G Q  +G  +     
Sbjct: 493 G-----PPGPQRYPIGIQGRTPGAMAGMQ---YP---QQQMPPQYGQQGVSGYCQ----- 536

Query: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQT-GPQQPQQFQGYGQQPTSQAPA--- 301
             Q Q  Y +QQPQ P   PQ    QY  S SQQ   PQQ    +GYG +  SQ P    
Sbjct: 537 --QGQQPYYSQQPQPPHLPPQA---QYLPSQSQQRYQPQQDMSQEGYGTR--SQPPLAPG 589

Query: 302 ------------------PAFSGQPQQLPA--------------QPPQQYQASNYPAQTY 329
                             P  SG    LP                   Q   SN PAQ+ 
Sbjct: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN-PAQSP 648

Query: 330 TAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGF---TSLPGSTMTPPPSGPNPYARNRP 386
            +  + P   ++     P    S  G+ Q R G     S+PGS M P P G    + + P
Sbjct: 649 FSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHP 708

Query: 387 PFGQ 390
              Q
Sbjct: 709 ALSQ 712



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 77/302 (25%), Positives = 101/302 (33%), Gaps = 45/302 (14%)

Query: 122 SLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNV 181
           S  PP    P +         G ++ +A    GK      AA+  A+   + +     + 
Sbjct: 386 SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP 445

Query: 182 MSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQP-PYTGAQTQAGQIE 240
            +  G T  +  G P  P   +      + S+      P  QPQQ  PY G     G   
Sbjct: 446 GTP-GPTMGRSQGSPMDPMVMKRPQLYGMGSN------PHSQPQQSSPYPGGSY--GPPG 496

Query: 241 GQMYQQYQQQAGYGAQQPQAPPQQ--PQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQ 298
            Q Y    Q    GA      PQQ  P QYG Q  + Y QQ   QQP     Y QQP   
Sbjct: 497 PQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQG--QQPY----YSQQPQP- 549

Query: 299 APAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQP---------TNYTVAPASQPGM 349
              P    Q Q LP+Q  Q+YQ     +Q      SQP          +  +    +P  
Sbjct: 550 ---PHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 606

Query: 350 APSQPGAYQPRP--------------GFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQP 395
            P   G+    P              G TS  G    P  S  +P+A        G   P
Sbjct: 607 LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSP 666

Query: 396 GP 397
            P
Sbjct: 667 SP 668



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/143 (30%), Positives = 53/143 (37%), Gaps = 21/143 (14%)

Query: 218  HPPGVQPQQPPYTGAQT-----QAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQY 272
            H PG+ PQQP Y           A + EG MY        Y +QQ +       QYG  Y
Sbjct: 1343 HQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQ-----YSSQQQE----MYNQYGGSY 1393

Query: 273  SAS-----YSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQ 327
            S         Q   P   ++ QG GQ  T   P     G  Q   ++ PQQ   +     
Sbjct: 1394 SGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDM 1453

Query: 328  TYTAQTSQ-PTNYTVAPASQPGM 349
             Y  Q  Q P   T AP   PGM
Sbjct: 1454 PYPYQNRQGPGGPTQAP-PYPGM 1475



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 52/201 (25%), Positives = 65/201 (32%), Gaps = 42/201 (20%)

Query: 233 QTQAGQIEGQMYQQYQQQ-----------AGYGAQQPQAPPQQPQQYGIQYSASYSQQTG 281
           Q Q  Q + Q  QQ QQQ           AG GA QP    +QPQ  G + SA+  Q   
Sbjct: 56  QQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP 115

Query: 282 PQQP----------------------QQFQGYGQQPTSQAP--APAFSGQPQQLPAQPPQ 317
           P  P                       +  G G   T Q P   P   G P  +P     
Sbjct: 116 PGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEF--N 173

Query: 318 QYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSG 377
            Y  S  PA       + P          PGM       +         PGS M P  + 
Sbjct: 174 NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM----MHSASAAAAGAPGS-MDPLQNS 228

Query: 378 PNPYARNRPPFGQGYTQPGPG 398
              Y  ++     GY++PG G
Sbjct: 229 HEGYPNSQCNHYPGYSRPGAG 249



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 69/261 (26%), Positives = 93/261 (35%), Gaps = 47/261 (18%)

Query: 148  SASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRS--- 204
            SA+ S  KQ  Q + A       ++  +E    V S  G T  Q    P +PA   S   
Sbjct: 1118 SAASSLKKQYIQYLFAFECK---IERGEEPPPEVFST-GDTKKQPKLQPPSPANSGSLQG 1173

Query: 205  -GTPDSIASSSSAAHPPGVQPQQPPYT--GAQT--QAGQIEG-QMYQQYQQQAGYG---- 254
              TP S  S+S A  P  ++P  P  T  G  T  Q G+     ++  +   +       
Sbjct: 1174 PQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKR 1233

Query: 255  -AQQPQAPPQQ----PQQYG-IQYSASYSQQTG----PQQPQQFQGYGQQPTS------- 297
             +  P AP QQ    P   G + Y  +     G    P   + F   GQ P S       
Sbjct: 1234 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1293

Query: 298  QAPAPAFS----GQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQ 353
            Q+P+ A S    GQ QQ P       +   Y  Q Y  Q          P+ QP     Q
Sbjct: 1294 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPY-GQQYPGQGP--------PSGQPPYGGHQ 1344

Query: 354  PGAYQPRPGFTSLPGSTMTPP 374
            PG Y  +P +         PP
Sbjct: 1345 PGLYPQQPNYKRHMDGMYGPP 1365



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 46/212 (21%), Positives = 71/212 (33%), Gaps = 29/212 (13%)

Query: 196  PSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGA 255
            P   + +R   P  I +        G   Q     G Q         M   YQ + G G 
Sbjct: 1406 PYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGG 1465

Query: 256  QQPQAPPQQ----------PQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS 305
               QAPP            P Q  I + + +      +QP        QP ++ P P++ 
Sbjct: 1466 PT-QAPPYPGMNRTDDMMVPDQR-INHESQWPSHVSQRQPYMSSSASMQPITRPPQPSY- 1522

Query: 306  GQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTS 365
                Q P   P     +  PA    +  ++     ++P+  P +   +     P     +
Sbjct: 1523 ----QTPPSLPNHISRAPSPASFQRSLENR-----MSPSKSPFLPSMKMQKVMP-----T 1568

Query: 366  LPGSTMTPPPSGPNPYAR--NRPPFGQGYTQP 395
            +P S +T PP  P P  R    PP     +QP
Sbjct: 1569 VPTSQVTGPPPQPPPIRREITFPPGSVEASQP 1600



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 61/234 (26%), Positives = 79/234 (33%), Gaps = 69/234 (29%)

Query: 188 TDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGA-----QTQAGQIEGQ 242
           T +Q+   PS       G+    +S S+   PP     Q    GA     Q  AG   G+
Sbjct: 360 TLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419

Query: 243 -MYQQY---------QQQAGYGAQQPQAP----------------PQQPQQYGI------ 270
            M  QY          QQ  + A  P  P                 ++PQ YG+      
Sbjct: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479

Query: 271 --QYSASY-SQQTGPQQPQQF----QG-------------------YGQQPTS----QAP 300
             Q S+ Y     GP  PQ++    QG                   YGQQ  S    Q  
Sbjct: 480 QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539

Query: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQP 354
            P +S QPQ  P  PPQ     +   Q Y  Q    +       SQP +AP +P
Sbjct: 540 QPYYSQQPQP-PHLPPQAQYLPSQSQQRYQPQQDM-SQEGYGTRSQPPLAPGKP 591



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 34/141 (24%), Positives = 47/141 (33%), Gaps = 24/141 (17%)

Query: 256  QQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQP 315
            +QP+  P  P   G        Q TG     +  G  + PT     PA +   Q  P Q 
Sbjct: 1156 KQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT-----PASTPHGQMTPMQG 1210

Query: 316  PQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPP 375
             +    S +   +  + +S P   ++ P      AP Q G   P                
Sbjct: 1211 GRSSTISVHDPFSDVSDSSFPKRNSMTPN-----APYQQGMSMP--------------DV 1251

Query: 376  SGPNPYARNRPPFGQGYTQPG 396
             G  PY  N+ PFG     PG
Sbjct: 1252 MGRMPYEPNKDPFGGMRKVPG 1272


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 79/304 (25%), Positives = 106/304 (34%), Gaps = 75/304 (24%)

Query: 126 PGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAF 185
           PG PGP+          GR + S  D    +  Q+     +   P     + +     ++
Sbjct: 445 PGTPGPTM---------GRSQGSPMDPMVMKRPQLYGMGSN---PHSQPQQSSPYPGGSY 492

Query: 186 GLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQ 245
           G       GP   P   +  TP ++A      +P   Q Q PP  G Q  +G  +     
Sbjct: 493 G-----PPGPQRYPIGIQGRTPGAMAGMQ---YP---QQQMPPQYGQQGVSGYCQ----- 536

Query: 246 QYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQT-GPQQPQQFQGYGQQPTSQAPA--- 301
             Q Q  Y +QQPQ P   PQ    QY  S SQQ   PQQ    +GYG +  SQ P    
Sbjct: 537 --QGQQPYYSQQPQPPHLPPQA---QYLPSQSQQRYQPQQDMSQEGYGTR--SQPPLAPG 589

Query: 302 ------------------PAFSGQPQQLPA--------------QPPQQYQASNYPAQTY 329
                             P  SG    LP                   Q   SN PAQ+ 
Sbjct: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN-PAQSP 648

Query: 330 TAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGF---TSLPGSTMTPPPSGPNPYARNRP 386
            +  + P   ++     P    S  G+ Q R G     S+PGS M P P G    + + P
Sbjct: 649 FSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHP 708

Query: 387 PFGQ 390
              Q
Sbjct: 709 ALSQ 712



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 77/302 (25%), Positives = 101/302 (33%), Gaps = 45/302 (14%)

Query: 122 SLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNV 181
           S  PP    P +         G ++ +A    GK      AA+  A+   + +     + 
Sbjct: 386 SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP 445

Query: 182 MSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQP-PYTGAQTQAGQIE 240
            +  G T  +  G P  P   +      + S+      P  QPQQ  PY G     G   
Sbjct: 446 GTP-GPTMGRSQGSPMDPMVMKRPQLYGMGSN------PHSQPQQSSPYPGGSY--GPPG 496

Query: 241 GQMYQQYQQQAGYGAQQPQAPPQQ--PQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQ 298
            Q Y    Q    GA      PQQ  P QYG Q  + Y QQ   QQP     Y QQP   
Sbjct: 497 PQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQG--QQPY----YSQQPQP- 549

Query: 299 APAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQP---------TNYTVAPASQPGM 349
              P    Q Q LP+Q  Q+YQ     +Q      SQP          +  +    +P  
Sbjct: 550 ---PHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 606

Query: 350 APSQPGAYQPRP--------------GFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQP 395
            P   G+    P              G TS  G    P  S  +P+A        G   P
Sbjct: 607 LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSP 666

Query: 396 GP 397
            P
Sbjct: 667 SP 668



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/143 (30%), Positives = 53/143 (37%), Gaps = 21/143 (14%)

Query: 218  HPPGVQPQQPPYTGAQT-----QAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQY 272
            H PG+ PQQP Y           A + EG MY        Y +QQ +       QYG  Y
Sbjct: 1290 HQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQ-----YSSQQQE----MYNQYGGSY 1340

Query: 273  SAS-----YSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQ 327
            S         Q   P   ++ QG GQ  T   P     G  Q   ++ PQQ   +     
Sbjct: 1341 SGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDM 1400

Query: 328  TYTAQTSQ-PTNYTVAPASQPGM 349
             Y  Q  Q P   T AP   PGM
Sbjct: 1401 PYPYQNRQGPGGPTQAP-PYPGM 1422



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 52/201 (25%), Positives = 65/201 (32%), Gaps = 42/201 (20%)

Query: 233 QTQAGQIEGQMYQQYQQQ-----------AGYGAQQPQAPPQQPQQYGIQYSASYSQQTG 281
           Q Q  Q + Q  QQ QQQ           AG GA QP    +QPQ  G + SA+  Q   
Sbjct: 56  QQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP 115

Query: 282 PQQP----------------------QQFQGYGQQPTSQAP--APAFSGQPQQLPAQPPQ 317
           P  P                       +  G G   T Q P   P   G P  +P     
Sbjct: 116 PGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEF--N 173

Query: 318 QYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSG 377
            Y  S  PA       + P          PGM       +         PGS M P  + 
Sbjct: 174 NYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM----MHSASAAAAGAPGS-MDPLQNS 228

Query: 378 PNPYARNRPPFGQGYTQPGPG 398
              Y  ++     GY++PG G
Sbjct: 229 HEGYPNSQCNHYPGYSRPGAG 249



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 69/261 (26%), Positives = 93/261 (35%), Gaps = 47/261 (18%)

Query: 148  SASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRS--- 204
            SA+ S  KQ  Q + A       ++  +E    V S  G T  Q    P +PA   S   
Sbjct: 1065 SAASSLKKQYIQYLFAFECK---IERGEEPPPEVFST-GDTKKQPKLQPPSPANSGSLQG 1120

Query: 205  -GTPDSIASSSSAAHPPGVQPQQPPYT--GAQT--QAGQIEG-QMYQQYQQQAGYG---- 254
              TP S  S+S A  P  ++P  P  T  G  T  Q G+     ++  +   +       
Sbjct: 1121 PQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKR 1180

Query: 255  -AQQPQAPPQQ----PQQYG-IQYSASYSQQTG----PQQPQQFQGYGQQPTS------- 297
             +  P AP QQ    P   G + Y  +     G    P   + F   GQ P S       
Sbjct: 1181 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1240

Query: 298  QAPAPAFS----GQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQ 353
            Q+P+ A S    GQ QQ P       +   Y  Q Y  Q          P+ QP     Q
Sbjct: 1241 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPY-GQQYPGQGP--------PSGQPPYGGHQ 1291

Query: 354  PGAYQPRPGFTSLPGSTMTPP 374
            PG Y  +P +         PP
Sbjct: 1292 PGLYPQQPNYKRHMDGMYGPP 1312



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 46/212 (21%), Positives = 71/212 (33%), Gaps = 29/212 (13%)

Query: 196  PSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGA 255
            P   + +R   P  I +        G   Q     G Q         M   YQ + G G 
Sbjct: 1353 PYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGG 1412

Query: 256  QQPQAPPQQ----------PQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS 305
               QAPP            P Q  I + + +      +QP        QP ++ P P++ 
Sbjct: 1413 PT-QAPPYPGMNRTDDMMVPDQR-INHESQWPSHVSQRQPYMSSSASMQPITRPPQPSY- 1469

Query: 306  GQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTS 365
                Q P   P     +  PA    +  ++     ++P+  P +   +     P     +
Sbjct: 1470 ----QTPPSLPNHISRAPSPASFQRSLENR-----MSPSKSPFLPSMKMQKVMP-----T 1515

Query: 366  LPGSTMTPPPSGPNPYAR--NRPPFGQGYTQP 395
            +P S +T PP  P P  R    PP     +QP
Sbjct: 1516 VPTSQVTGPPPQPPPIRREITFPPGSVEASQP 1547



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 61/234 (26%), Positives = 79/234 (33%), Gaps = 69/234 (29%)

Query: 188 TDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGA-----QTQAGQIEGQ 242
           T +Q+   PS       G+    +S S+   PP     Q    GA     Q  AG   G+
Sbjct: 360 TLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419

Query: 243 -MYQQY---------QQQAGYGAQQPQAP----------------PQQPQQYGI------ 270
            M  QY          QQ  + A  P  P                 ++PQ YG+      
Sbjct: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479

Query: 271 --QYSASY-SQQTGPQQPQQF----QG-------------------YGQQPTS----QAP 300
             Q S+ Y     GP  PQ++    QG                   YGQQ  S    Q  
Sbjct: 480 QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539

Query: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQP 354
            P +S QPQ  P  PPQ     +   Q Y  Q    +       SQP +AP +P
Sbjct: 540 QPYYSQQPQP-PHLPPQAQYLPSQSQQRYQPQQDM-SQEGYGTRSQPPLAPGKP 591



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 34/141 (24%), Positives = 47/141 (33%), Gaps = 24/141 (17%)

Query: 256  QQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQP 315
            +QP+  P  P   G        Q TG     +  G  + PT     PA +   Q  P Q 
Sbjct: 1103 KQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPT-----PASTPHGQMTPMQG 1157

Query: 316  PQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPP 375
             +    S +   +  + +S P   ++ P      AP Q G   P                
Sbjct: 1158 GRSSTISVHDPFSDVSDSSFPKRNSMTPN-----APYQQGMSMP--------------DV 1198

Query: 376  SGPNPYARNRPPFGQGYTQPG 396
             G  PY  N+ PFG     PG
Sbjct: 1199 MGRMPYEPNKDPFGGMRKVPG 1219


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 67/274 (24%), Positives = 96/274 (35%), Gaps = 47/274 (17%)

Query: 129 PGPSTNIP-ENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGL 187
           PG  +  P E++T   R  K A ++ G    Q  A  +    P + +D   K        
Sbjct: 27  PGHPSQPPLEDNTPATRTTKGAREAGG----QAQAMELPEAQPRQARDGELK-------- 74

Query: 188 TDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQY 247
                  PPS   +  S TP    S  +   PPG  P Q P       AG+ EG   Q+Y
Sbjct: 75  -------PPSLRGQAPSSTPGKRGSPQT---PPGRSPLQAP----SRLAGRAEGSPPQRY 120

Query: 248 QQQAGYGAQQP--QAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFS 305
                    +P     P+ PQ      +A   +   PQ P    G G       P     
Sbjct: 121 ILGIASSRTKPTLDETPENPQLE----AAQLPEVDTPQGP----GTGAPLRPGLPRTEAQ 172

Query: 306 GQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQ------- 358
              ++L      Q   S++ +  YT+ ++ P      P    G +P QPG+Y        
Sbjct: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGA 232

Query: 359 ---PRPGFTSLPGSTMTPPPSGPNPYARNRPPFG 389
              P     S PG+    PP+ P P  +   P G
Sbjct: 233 DSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGG 266



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 74/314 (23%), Positives = 113/314 (35%), Gaps = 57/314 (18%)

Query: 126  PGEPGPSTN--IPENDTVDGREEKSASDSSGKQSTQVMAASMSA-------------FDP 170
            PG PGP     +P   ++  R      D+ GK++  V +    A              D 
Sbjct: 3556 PGSPGPLLQQALPLGASLP-RPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPDHFQEDH 3614

Query: 171  L--KNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPD-SIASSSSAAHPPGVQPQQP 227
            L  K ++  + +++S  G       G  + PA  +S + D S AS+ S A    V P++ 
Sbjct: 3615 LLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKA 3674

Query: 228  PYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQ 287
               G+        G        + G     P+A P  P   G       ++  G  QPQ 
Sbjct: 3675 --VGSLAPGELARGT-------ENGMKPATPKAKPG-PSSQGSGSPRPGTKTGGGSQPQP 3724

Query: 288  FQGYGQQPTSQAPA----PAFSGQPQQLPAQP-------------PQQYQASNYPAQTYT 330
              G  Q  T+  PA    P+ S  P++LPA+               Q    S  P +   
Sbjct: 3725 ASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGE 3784

Query: 331  AQTSQPTNYTVAPASQP-----GMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNR 385
            + T +       PA        G APS P      P   + P   +   P+ P P ++N+
Sbjct: 3785 SSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVL---PTKPKPNSQNK 3841

Query: 386  ---PPFGQGYTQPG 396
               PP  Q   +PG
Sbjct: 3842 PRPPPSEQRKAEPG 3855



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 51/212 (24%), Positives = 80/212 (37%), Gaps = 48/212 (22%)

Query: 223  QPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQP-QQYGIQYSASYSQQTG 281
            + +QPP  G   +  +  G+  ++ +   G    +PQ P +   Q+ G   + +  ++ G
Sbjct: 1072 EDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG 1131

Query: 282  PQQPQQFQGYGQQPTSQAPA-------------PAFSGQPQQLPAQP---PQQYQAS--- 322
              +P    G G+ P ++ P+             P  + +P   P  P   P   + S   
Sbjct: 1132 GSRP----GPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEET 1187

Query: 323  ----NYPAQT---YTAQTSQP--TNYTVAPASQPGMAPSQPGA-------YQPRPGFTSL 366
                ++P +     TA+ S P  T +T A  S P     + GA        QP P     
Sbjct: 1188 RPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPS---- 1243

Query: 367  PGSTMTPPPSGPNPYARNRPPFGQGYTQPGPG 398
               T TP PSG      N  P G   T PG G
Sbjct: 1244 RHDTGTPKPSGS---LANTAPHGSSPT-PGVG 1271


>gi|73695473 roquin [Homo sapiens]
          Length = 1133

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 74/323 (22%), Positives = 109/323 (33%), Gaps = 55/323 (17%)

Query: 98  ESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQS 157
           E  + + + + L+  R  ++  L  L   G P  +  +P+   VD    K  +  +G  S
Sbjct: 442 ELEKFRKMNKRLVP-RRPLSASLGQLNEVGLPSAAI-LPDEGAVDLPSRKPPALPNGIVS 499

Query: 158 TQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAA 217
           T     +++   P       + ++    G  D   S  P +P +     P SI++     
Sbjct: 500 T---GNTVTQLIPRGTDPSYDSSLKP--GKIDHLSSSAPGSPPDLLESVPKSISALPVNP 554

Query: 218 H--PPGVQPQQPPYTGAQTQAGQIEG-QMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSA 274
           H  PP      PP    +       G Q+Y   Q    Y   +  APP +P        A
Sbjct: 555 HSIPPRGPADLPPMPVTKPLQMVPRGSQLYPAQQTDVYYQDPRGAAPPFEP--------A 606

Query: 275 SYSQQTGPQQPQQFQGYGQQPTSQAPAPA-------------------FSGQPQQLPAQP 315
            Y Q      P Q      +P   AP PA                   +  QPQQ P   
Sbjct: 607 PYQQGMYYTPPPQCVSRFVRPPPSAPEPAPPYLDHYPPYLQERVVNSQYGTQPQQYPPIY 666

Query: 316 PQQYQASN-YPAQTYTAQT---SQPTNYTVAPASQPGMAPSQPGAYQP------------ 359
           P  Y     YPA +YT +      P    + PA+ P   P     YQ             
Sbjct: 667 PSHYDGRRVYPAPSYTREEIFRESPIPIEIPPAAVPSYVPESRERYQQIESYYPVAPHPT 726

Query: 360 --RPGFTSLPGSTMTPPPSGPNP 380
             RP +   P  +  PPP  P+P
Sbjct: 727 QIRPSYLREPPYSRLPPPPQPHP 749


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 71/265 (26%), Positives = 94/265 (35%), Gaps = 35/265 (13%)

Query: 129 PGPSTNIPENDT----VDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSA 184
           P  ST IP   T    V  + E    ++   Q  Q    S+S             +V + 
Sbjct: 607 PSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTE 666

Query: 185 FGLTDDQVS--GPPSAPAEDRSGTPDSIASSSSA-AHPPGVQP-------QQPPYTGAQT 234
             ++  Q    G     A      P  I S+  A + P GV P       Q      + +
Sbjct: 667 SRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSS 726

Query: 235 QAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQT------GPQQPQ-- 286
             G    Q  Q  QQQ G    Q  APPQQ  QY +  +++ S+ T       PQ PQ  
Sbjct: 727 LTGVSSSQPIQHPQQQQGI---QQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVL 783

Query: 287 -QFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQT--YTAQTSQPTNYTVAP 343
            Q     Q P SQ P P   G+P     Q P   Q S  P  +  +     QP    + P
Sbjct: 784 PQVSAGKQLPVSQ-PVPTIQGEP-----QIPVATQPSVVPVHSGAHFLPVGQPLPTPLLP 837

Query: 344 ASQPGMAP-SQPGAYQPRPGFTSLP 367
                  P S P     + GF+SLP
Sbjct: 838 QYPVSQIPISTPHVSTAQTGFSSLP 862



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 65/262 (24%), Positives = 91/262 (34%), Gaps = 65/262 (24%)

Query: 144 REEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDR 203
           +E+K   +SS KQ  +  +AS +    L                        PSA     
Sbjct: 579 QEKKKQEESSLKQQVEQSSASQTGIKQL------------------------PSAS---- 610

Query: 204 SGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQ--------QQAGYGA 255
           +G P   AS++SA+    V+P++P       +A Q +   YQQ            +G G+
Sbjct: 611 TGIPT--ASTTSASVSTQVEPEEP-------EADQHQQLQYQQPSISVLSDGTVDSGQGS 661

Query: 256 Q---QPQAPPQQPQQYGIQYSASYSQQTGPQQ-----PQQFQGYGQQPTSQAPAPAFSGQ 307
               + +   QQ   YG Q+  ++S  T P         Q Q +G  P S        GQ
Sbjct: 662 SVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQ 721

Query: 308 PQQL---------PAQPPQQYQASNY---PAQTYTAQTSQPTNYTVAPASQPGMAPSQPG 355
           P            P Q PQQ Q       P QT     SQ +  + A  +QP   P  P 
Sbjct: 722 PSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQ 781

Query: 356 AYQPRPGFTSLPGSTMTPPPSG 377
                     LP S   P   G
Sbjct: 782 VLPQVSAGKQLPVSQPVPTIQG 803



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 9/62 (14%)

Query: 298  QAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAY 357
            QA  P  +    Q+P+ PP     +N PA   T   SQP         QP + P+QP  +
Sbjct: 1584 QAAGPTSTPLLPQVPSIPPLVQPVANVPAVQQTLIHSQP---------QPALLPNQPHTH 1634

Query: 358  QP 359
             P
Sbjct: 1635 CP 1636


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 64/219 (29%), Positives = 74/219 (33%), Gaps = 26/219 (11%)

Query: 194 GPPSAPAEDRS-----------GTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQ-IEG 241
           GPP +P +  S           G P+ ++S  S   P    PQ PP     +Q G  I G
Sbjct: 107 GPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGP--TPPQMPP-----SQPGALIPG 159

Query: 242 QMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQ-QFQGYGQQPTSQAP 300
                 Q   G     P    Q   Q  + Y      Q  P+  Q   QG    P  Q  
Sbjct: 160 DPQAMSQPNRGPSPFSPVQLHQLRAQI-LAYKMLARGQPLPETLQLAVQGKRTLPGLQQQ 218

Query: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR 360
                 Q QQ   Q  QQ Q    P Q  T Q  QP        S PG   S P   Q  
Sbjct: 219 QQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKL 278

Query: 361 PGFTSLPGSTMTP-PPSGPNPYARNRPPFGQGYTQPGPG 398
           P     PG   +P PP+   P A   P  G    QP PG
Sbjct: 279 P--VPAPGGRPSPAPPAAAQPPAAAVP--GPSVPQPAPG 313


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 64/219 (29%), Positives = 74/219 (33%), Gaps = 26/219 (11%)

Query: 194 GPPSAPAEDRS-----------GTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQ-IEG 241
           GPP +P +  S           G P+ ++S  S   P    PQ PP     +Q G  I G
Sbjct: 107 GPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGP--TPPQMPP-----SQPGALIPG 159

Query: 242 QMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQ-QFQGYGQQPTSQAP 300
                 Q   G     P    Q   Q  + Y      Q  P+  Q   QG    P  Q  
Sbjct: 160 DPQAMSQPNRGPSPFSPVQLHQLRAQI-LAYKMLARGQPLPETLQLAVQGKRTLPGLQQQ 218

Query: 301 APAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPR 360
                 Q QQ   Q  QQ Q    P Q  T Q  QP        S PG   S P   Q  
Sbjct: 219 QQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKL 278

Query: 361 PGFTSLPGSTMTP-PPSGPNPYARNRPPFGQGYTQPGPG 398
           P     PG   +P PP+   P A   P  G    QP PG
Sbjct: 279 P--VPAPGGRPSPAPPAAAQPPAAAVP--GPSVPQPAPG 313


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,364,689
Number of Sequences: 37866
Number of extensions: 1274548
Number of successful extensions: 13178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 247
Number of HSP's successfully gapped in prelim test: 1076
Number of HSP's that attempted gapping in prelim test: 7138
Number of HSP's gapped (non-prelim): 4443
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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