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Search of human proteins with 21359963
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
(731 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 1473 0.0
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 1413 0.0
gi|23199987 WD repeat domain 5B [Homo sapiens] 92 2e-18
gi|16554629 WD repeat domain 5 [Homo sapiens] 91 4e-18
gi|16554627 WD repeat domain 5 [Homo sapiens] 91 4e-18
gi|21071067 TBP-associated factor 5 [Homo sapiens] 89 1e-17
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 75 3e-13
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 75 3e-13
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 75 3e-13
gi|26665869 WD repeat domain 51B [Homo sapiens] 75 3e-13
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 73 1e-12
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 71 3e-12
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 67 6e-11
gi|32189425 WD repeat domain 69 [Homo sapiens] 64 5e-10
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 64 7e-10
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 64 7e-10
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 64 7e-10
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 62 1e-09
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 62 2e-09
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 62 2e-09
gi|113865883 WD repeat domain 38 [Homo sapiens] 62 2e-09
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 62 2e-09
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 61 3e-09
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 61 3e-09
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 61 3e-09
gi|19913367 transducin beta-like 1Y [Homo sapiens] 61 3e-09
gi|19913365 transducin beta-like 1Y [Homo sapiens] 61 3e-09
gi|15150805 transducin beta-like 1Y [Homo sapiens] 61 3e-09
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 61 4e-09
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 61 4e-09
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 1473 bits (3813), Expect = 0.0
Identities = 731/731 (100%), Positives = 731/731 (100%)
Query: 1 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG 60
MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
Sbjct: 1 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG 60
Query: 61 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC 120
LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
Sbjct: 61 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC 120
Query: 121 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI 180
NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
Sbjct: 121 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI 180
Query: 181 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL 240
DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL
Sbjct: 181 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL 240
Query: 241 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS 300
MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS
Sbjct: 241 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS 300
Query: 301 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL 360
GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
Sbjct: 301 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL 360
Query: 361 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG 420
TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
Sbjct: 361 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG 420
Query: 421 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 480
SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
Sbjct: 421 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 480
Query: 481 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL 540
YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
Sbjct: 481 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL 540
Query: 541 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK 600
WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
Sbjct: 541 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK 600
Query: 601 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 660
AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
Sbjct: 601 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 660
Query: 661 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN 720
NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
Sbjct: 661 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN 720
Query: 721 SQGTIKVLELV 731
SQGTIKVLELV
Sbjct: 721 SQGTIKVLELV 731
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 1413 bits (3657), Expect = 0.0
Identities = 707/731 (96%), Positives = 707/731 (96%), Gaps = 24/731 (3%)
Query: 1 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG 60
MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG
Sbjct: 1 MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGG 60
Query: 61 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC 120
LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC
Sbjct: 61 LGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLC 120
Query: 121 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI 180
NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI
Sbjct: 121 NGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI 180
Query: 181 DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNL 240
DHLYPNFLVNELILKQKQRFEEKRFKLDHS NGHRWQIFQDWLGTDQDNLDLANVNL
Sbjct: 181 DHLYPNFLVNELILKQKQRFEEKRFKLDHS----NGHRWQIFQDWLGTDQDNLDLANVNL 236
Query: 241 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMS 300
MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKRE EMS
Sbjct: 237 MLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKRE--------------------EMS 276
Query: 301 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL 360
GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL
Sbjct: 277 GLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL 336
Query: 361 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG 420
TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG
Sbjct: 337 TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNG 396
Query: 421 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 480
SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS
Sbjct: 397 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 456
Query: 481 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL 540
YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL
Sbjct: 457 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL 516
Query: 541 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK 600
WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK
Sbjct: 517 WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK 576
Query: 601 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 660
AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE
Sbjct: 577 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 636
Query: 661 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN 720
NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN
Sbjct: 637 NNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAAN 696
Query: 721 SQGTIKVLELV 731
SQGTIKVLELV
Sbjct: 697 SQGTIKVLELV 707
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 92.0 bits (227), Expect = 2e-18
Identities = 73/258 (28%), Positives = 127/258 (49%), Gaps = 19/258 (7%)
Query: 417 LYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCI 476
L + VSS++F + ++ A + + I +I A D Y + N +IS +
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLI-------IIWGAYDGKYEKTLYGHNLEISDV 89
Query: 477 SWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDA 536
+WSS L+++SD + T+ LWD +G+ K + H + +FN L+ SGS D
Sbjct: 90 AWSSDSSRLVSASD-DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFN-PPSNLIISGSFDE 147
Query: 537 KVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVF 595
VK+W + ++ A ++ V V F+ S + G D +D + + +
Sbjct: 148 TVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSL-IVSGSYDGLCRIWDAASGQCLKTLV 206
Query: 596 KGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEK-----NFVGLA 649
VS+ KF +G+ I++A+ D+ LKLW+ + CL+++ GH NEK NF
Sbjct: 207 DDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANF--SV 264
Query: 650 SNGDYIACGSENNSLYLY 667
+ G +I GSE+N +Y++
Sbjct: 265 TGGKWIVSGSEDNLVYIW 282
Score = 74.7 bits (182), Expect = 3e-13
Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 6/196 (3%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
LASS + +I+W + G+ K H V ++ D L S SDD +KLW
Sbjct: 56 LASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWS-SDSSRLVSASDDKTLKLWDVRS 114
Query: 546 DNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSY 604
+ +++ +N V C F+P S ++ G D V ++++ T + + H VS
Sbjct: 115 GKCLKTLKGHSNYVFCCNFNPPSNLIIS-GSFDETVKIWEVK-TGKCLKTLSAHSDPVSA 172
Query: 605 AKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEK-NFVGLASNGDYIACGSENN 662
F SG IVS S D ++W+ CL++ N +FV + NG YI + +N
Sbjct: 173 VHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDN 232
Query: 663 SLYLYYKGLSKTLLTF 678
+L L+ + L T+
Sbjct: 233 TLKLWDYSRGRCLKTY 248
Score = 47.8 bits (112), Expect = 4e-05
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%)
Query: 558 VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVS-GEEIVSA 616
V VKFSP+ + LA AD + + + K ++ GH +S + S +VSA
Sbjct: 44 VSSVKFSPNGEW-LASSSADRLIIIWGAYDGKYEKTLY-GHNLEISDVAWSSDSSRLVSA 101
Query: 617 STDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLL 676
S D LKLW+V CL++ KGH N + I GS + ++ ++ K L
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLK 161
Query: 677 T 677
T
Sbjct: 162 T 162
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 470 NSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEH--EKRCWSVDFNLMDPK 527
N +S + +S K +L ++ + T+ LWD G+ K Y H EK C +F++ K
Sbjct: 210 NPPVSFVKFSPNGKYILTAT-LDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGK 268
Query: 528 LLASGSDDAKVKLWSTNLDNSVASIEAKANV 558
+ SGS+D V +W+ V ++ +V
Sbjct: 269 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 597 GHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYI 655
GH +AVS KF +GE + S+S D + +W ++ GH E + V +S+ +
Sbjct: 39 GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRL 98
Query: 656 ACGSENNSLYLYYKGLSKTLLTFK 679
S++ +L L+ K L T K
Sbjct: 99 VSASDDKTLKLWDVRSGKCLKTLK 122
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 90.9 bits (224), Expect = 4e-18
Identities = 74/271 (27%), Positives = 129/271 (47%), Gaps = 23/271 (8%)
Query: 405 VRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVY-EYDTVIQDAVDIHYP 463
V+P L + L + VSS++F + ++ A + K IK++ YD + + H
Sbjct: 31 VKPNYALKFT--LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH-- 86
Query: 464 ENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNL 523
IS ++WSS NLL S+ + T+ +WD +G+ K + H + +FN
Sbjct: 87 ------KLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNP 139
Query: 524 MDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHY 582
L+ SGS D V++W + ++ A ++ V V F+ + D
Sbjct: 140 QS-NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSL-IVSSSYDGLCRI 197
Query: 583 YDLRNTKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHIN 641
+D + + + VS+ KF +G+ I++A+ D+ LKLW+ K CL+++ GH N
Sbjct: 198 WDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKN 257
Query: 642 EK-----NFVGLASNGDYIACGSENNSLYLY 667
EK NF + G +I GSE+N +Y++
Sbjct: 258 EKYCIFANF--SVTGGKWIVSGSEDNLVYIW 286
Score = 74.7 bits (182), Expect = 3e-13
Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 6/196 (3%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
LASS + + +W + G+ K H+ V ++ D LL S SDD +K+W +
Sbjct: 60 LASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLLVSASDDKTLKIWDVSS 118
Query: 546 DNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSY 604
+ +++ +N V C F+P S + G D V +D++ T + + H VS
Sbjct: 119 GKCLKTLKGHSNYVFCCNFNPQSNL-IVSGSFDESVRIWDVK-TGKCLKTLPAHSDPVSA 176
Query: 605 AKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEK-NFVGLASNGDYIACGSENN 662
F G IVS+S D ++W+ CL++ N +FV + NG YI + +N
Sbjct: 177 VHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDN 236
Query: 663 SLYLYYKGLSKTLLTF 678
+L L+ K L T+
Sbjct: 237 TLKLWDYSKGKCLKTY 252
Score = 49.7 bits (117), Expect = 1e-05
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%)
Query: 558 VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEI-VSA 616
V VKFSP+ + LA AD + + + K + GH+ +S + S + VSA
Sbjct: 48 VSSVKFSPNGEW-LASSSADKLIKIWGAYDGKFEKTI-SGHKLGISDVAWSSDSNLLVSA 105
Query: 617 STDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLL 676
S D LK+W+V CL++ KGH N + I GS + S+ ++ K L
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 677 T 677
T
Sbjct: 166 T 166
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/140 (25%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 421 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 480
S VS++ F+RD + +++ DT + ++ N +S + +S
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIW--DTASGQCLKTLIDDD----NPPVSFVKFSP 224
Query: 481 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEH--EKRCWSVDFNLMDPKLLASGSDDAKV 538
K +LA++ + T+ LWD G+ K Y H EK C +F++ K + SGS+D V
Sbjct: 225 NGKYILAAT-LDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLV 283
Query: 539 KLWSTNLDNSVASIEAKANV 558
+W+ V ++ +V
Sbjct: 284 YIWNLQTKEIVQKLQGHTDV 303
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 597 GHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYI 655
GH KAVS KF +GE + S+S D +K+W ++ GH + V +S+ + +
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102
Query: 656 ACGSENNSLYLYYKGLSKTLLTFK 679
S++ +L ++ K L T K
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLK 126
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 90.9 bits (224), Expect = 4e-18
Identities = 74/271 (27%), Positives = 129/271 (47%), Gaps = 23/271 (8%)
Query: 405 VRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVY-EYDTVIQDAVDIHYP 463
V+P L + L + VSS++F + ++ A + K IK++ YD + + H
Sbjct: 31 VKPNYALKFT--LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH-- 86
Query: 464 ENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNL 523
IS ++WSS NLL S+ + T+ +WD +G+ K + H + +FN
Sbjct: 87 ------KLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNP 139
Query: 524 MDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHY 582
L+ SGS D V++W + ++ A ++ V V F+ + D
Sbjct: 140 QS-NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSL-IVSSSYDGLCRI 197
Query: 583 YDLRNTKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHIN 641
+D + + + VS+ KF +G+ I++A+ D+ LKLW+ K CL+++ GH N
Sbjct: 198 WDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKN 257
Query: 642 EK-----NFVGLASNGDYIACGSENNSLYLY 667
EK NF + G +I GSE+N +Y++
Sbjct: 258 EKYCIFANF--SVTGGKWIVSGSEDNLVYIW 286
Score = 74.7 bits (182), Expect = 3e-13
Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 6/196 (3%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
LASS + + +W + G+ K H+ V ++ D LL S SDD +K+W +
Sbjct: 60 LASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLLVSASDDKTLKIWDVSS 118
Query: 546 DNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSY 604
+ +++ +N V C F+P S + G D V +D++ T + + H VS
Sbjct: 119 GKCLKTLKGHSNYVFCCNFNPQSNL-IVSGSFDESVRIWDVK-TGKCLKTLPAHSDPVSA 176
Query: 605 AKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEK-NFVGLASNGDYIACGSENN 662
F G IVS+S D ++W+ CL++ N +FV + NG YI + +N
Sbjct: 177 VHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDN 236
Query: 663 SLYLYYKGLSKTLLTF 678
+L L+ K L T+
Sbjct: 237 TLKLWDYSKGKCLKTY 252
Score = 49.7 bits (117), Expect = 1e-05
Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 3/121 (2%)
Query: 558 VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEI-VSA 616
V VKFSP+ + LA AD + + + K + GH+ +S + S + VSA
Sbjct: 48 VSSVKFSPNGEW-LASSSADKLIKIWGAYDGKFEKTI-SGHKLGISDVAWSSDSNLLVSA 105
Query: 617 STDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLL 676
S D LK+W+V CL++ KGH N + I GS + S+ ++ K L
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 677 T 677
T
Sbjct: 166 T 166
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/140 (25%), Positives = 64/140 (45%), Gaps = 9/140 (6%)
Query: 421 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 480
S VS++ F+RD + +++ DT + ++ N +S + +S
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIW--DTASGQCLKTLIDDD----NPPVSFVKFSP 224
Query: 481 YHKNLLASSDYEGTVILWDGFTGQRSKVYQEH--EKRCWSVDFNLMDPKLLASGSDDAKV 538
K +LA++ + T+ LWD G+ K Y H EK C +F++ K + SGS+D V
Sbjct: 225 NGKYILAAT-LDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLV 283
Query: 539 KLWSTNLDNSVASIEAKANV 558
+W+ V ++ +V
Sbjct: 284 YIWNLQTKEIVQKLQGHTDV 303
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 597 GHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYI 655
GH KAVS KF +GE + S+S D +K+W ++ GH + V +S+ + +
Sbjct: 43 GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102
Query: 656 ACGSENNSLYLYYKGLSKTLLTFK 679
S++ +L ++ K L T K
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLK 126
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 89.0 bits (219), Expect = 1e-17
Identities = 173/800 (21%), Positives = 307/800 (38%), Gaps = 124/800 (15%)
Query: 7 AGSGSAGTS---PGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGG 63
AG GS GT+ P + S+S+ P+VAVSAAA AA
Sbjct: 32 AGEGSGGTTNNGPNGGGGNVAASSSTGGDGGTPKPTVAVSAAAPAGAAPVPAAAPDAGAP 91
Query: 64 PVRPVLVA-------------------------PAVSGSG--------GGAVSTGLSRHS 90
R L+A AV+GSG G V++ L
Sbjct: 92 HDRQTLLAVLQFLRQSKLREAEEALRREAGLLEEAVAGSGAPGEVDSAGAEVTSALLSRV 151
Query: 91 CAARPSA------GVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIE 144
A+ P G G S +++ SGS P AP G + + ED+ + ++
Sbjct: 152 TASAPGPAAPDPPGTGASGATVVSGSASGPA-APGKVGSV-AVEDQPDVSAVLSAYNQQG 209
Query: 145 EAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELILKQKQRFE--- 201
+ M + +S I SL D +R H+Y + N+ + K FE
Sbjct: 210 DPTMYEEYYSGLKHFIECSL-DCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFH 268
Query: 202 ---EKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQK----KKQLEA 254
E ++ D V S+ + + + ++ LD +L + K+ L+
Sbjct: 269 GDQECYYQDDLRVLSSLTKK-----EHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQE 323
Query: 255 ESHAAQLQILMEFLKV-----ARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSED 309
+ + I+ E L + R+K +QI + L + KR S ++ + ++
Sbjct: 324 KQNNQIWNIVQEHLYIDIFDGMPRSK----QQIDAMVGSLAGEAKREANKSKVFFGLLKE 379
Query: 310 STVPQFEAPSPSHSSIIDSTE----YSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFE 365
P+ E P ++ E +P S S++KKQ A + R+
Sbjct: 380 ---PEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQ----DPNAPPQNRIP---- 428
Query: 366 DLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVS 425
L + S ++ +I + T ++ +CL Y + L+ A D+ + SS+++
Sbjct: 429 -LPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLT-AVDVTDDSSLIA 486
Query: 426 SIEFDRDCDYFAIAGVTKKIKVY-----------EYDTVIQDAVDIHYPENEMTCNSKIS 474
D +++ KK++ E D V++ +D
Sbjct: 487 GGFADSTVRVWSVT--PKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSG 544
Query: 475 CISWSSYH--KNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
+ +S+ +N L SS +GTV LW T Y+ H W F+ SG
Sbjct: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYG-YYFVSG 603
Query: 533 SDDAKVKLWSTNLDNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQP 591
D +LW+T+ + A+V C +F P+S Y +A G AD V +D+ N
Sbjct: 604 GHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNY-VATGSADRTVRLWDVLNGNC- 661
Query: 592 IMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLAS 650
+ +F GH+ + F +G + + +TD ++ LW++G + KGH + + +
Sbjct: 662 VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR 721
Query: 651 NGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPD 710
+G+ +A GS +N++ L+ D +K+ D +T++F +A LP+
Sbjct: 722 DGEILASGSMDNTVRLW-------------DAIKAFEDL-----ETDDFTTATGHINLPE 763
Query: 711 GESNVLIAANSQGTIKVLEL 730
+L+ + V+ L
Sbjct: 764 NSQELLLGTYMTKSTPVVHL 783
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 74.7 bits (182), Expect = 3e-13
Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 13/167 (7%)
Query: 476 ISWSSYHKNLLASSDYEGTVILWD-------GFTGQRSKVYQEHEKRCWSVDFNLMDPKL 528
+SW+ L S+ + T+ LWD G ++ H V ++L+ L
Sbjct: 148 LSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESL 207
Query: 529 LASGSDDAKVKLWSTNLDNSVA---SIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYD 584
S +DD K+ +W T +N+ S++A A V C+ F+P S + LA G AD V +D
Sbjct: 208 FGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWD 267
Query: 585 LRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSAS--TDSQLKLWNVGK 629
LRN K + F+ H+ + ++ E + AS TD +L +W++ K
Sbjct: 268 LRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSK 314
Score = 38.5 bits (88), Expect = 0.022
Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKV--YQEHEKRCWSVDFNLMDPKL 528
++++C+S++ Y + +LA+ + TV LWD + K+ ++ H+ + V ++ + +
Sbjct: 239 AEVNCLSFNPYSEFILATGSADKTVALWD-LRNLKLKLHSFESHKDEIFQVQWSPHNETI 297
Query: 529 LASGSDDAKVKLW 541
LAS D ++ +W
Sbjct: 298 LASSGTDRRLNVW 310
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 74.7 bits (182), Expect = 3e-13
Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 13/167 (7%)
Query: 476 ISWSSYHKNLLASSDYEGTVILWD-------GFTGQRSKVYQEHEKRCWSVDFNLMDPKL 528
+SW+ L S+ + T+ LWD G ++ H V ++L+ L
Sbjct: 182 LSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESL 241
Query: 529 LASGSDDAKVKLWSTNLDNSVA---SIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYD 584
S +DD K+ +W T +N+ S++A A V C+ F+P S + LA G AD V +D
Sbjct: 242 FGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWD 301
Query: 585 LRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSAS--TDSQLKLWNVGK 629
LRN K + F+ H+ + ++ E + AS TD +L +W++ K
Sbjct: 302 LRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSK 348
Score = 38.5 bits (88), Expect = 0.022
Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKV--YQEHEKRCWSVDFNLMDPKL 528
++++C+S++ Y + +LA+ + TV LWD + K+ ++ H+ + V ++ + +
Sbjct: 273 AEVNCLSFNPYSEFILATGSADKTVALWD-LRNLKLKLHSFESHKDEIFQVQWSPHNETI 331
Query: 529 LASGSDDAKVKLW 541
LAS D ++ +W
Sbjct: 332 LASSGTDRRLNVW 344
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 74.7 bits (182), Expect = 3e-13
Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 13/167 (7%)
Query: 476 ISWSSYHKNLLASSDYEGTVILWD-------GFTGQRSKVYQEHEKRCWSVDFNLMDPKL 528
+SW+ L S+ + T+ LWD G ++ H V ++L+ L
Sbjct: 183 LSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESL 242
Query: 529 LASGSDDAKVKLWSTNLDNSVA---SIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYD 584
S +DD K+ +W T +N+ S++A A V C+ F+P S + LA G AD V +D
Sbjct: 243 FGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWD 302
Query: 585 LRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSAS--TDSQLKLWNVGK 629
LRN K + F+ H+ + ++ E + AS TD +L +W++ K
Sbjct: 303 LRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSK 349
Score = 38.5 bits (88), Expect = 0.022
Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKV--YQEHEKRCWSVDFNLMDPKL 528
++++C+S++ Y + +LA+ + TV LWD + K+ ++ H+ + V ++ + +
Sbjct: 274 AEVNCLSFNPYSEFILATGSADKTVALWD-LRNLKLKLHSFESHKDEIFQVQWSPHNETI 332
Query: 529 LASGSDDAKVKLW 541
LAS D ++ +W
Sbjct: 333 LASSGTDRRLNVW 345
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 74.7 bits (182), Expect = 3e-13
Identities = 60/191 (31%), Positives = 93/191 (48%), Gaps = 13/191 (6%)
Query: 480 SYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVK 539
S H NLLAS+ + TV LW + ++ H SVDF+ D + LA+ S+D +K
Sbjct: 69 SPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFS-ADGQFLATASEDKSIK 127
Query: 540 LWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCA-DHCVHYYDLRNTKQPIMVFKG 597
+WS + S+ + V C KFSP R L C+ D + +D N KQ + F
Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSPDGR--LIVSCSEDKTIKIWDTTN-KQCVNNFS- 183
Query: 598 HRKAVSYAKFV----SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGD 653
+V +A FV SG I SA +D +K+W+V L+ ++ H N + +G+
Sbjct: 184 --DSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGN 241
Query: 654 YIACGSENNSL 664
Y+ S + +L
Sbjct: 242 YLITASSDGTL 252
Score = 67.4 bits (163), Expect = 5e-11
Identities = 64/248 (25%), Positives = 109/248 (43%), Gaps = 24/248 (9%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
LA++ ++ ++LW+ R+ Y H+ SV F+ LLAS S D V+LW +
Sbjct: 33 LATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFS-PHGNLLASASRDRTVRLWIPDK 91
Query: 546 DNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSY 604
+ +A A V V FS ++ LA D + + + + +++ H V
Sbjct: 92 RGKFSEFKAHTAPVRSVDFSADGQF-LATASEDKSIKVWSMYRQRFLYSLYR-HTHWVRC 149
Query: 605 AKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNS 663
AKF G IVS S D +K+W+ C+ +F + NFV +G IA + +
Sbjct: 150 AKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQT 209
Query: 664 LYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQG 723
+ ++ ++K L ++ + C P G N LI A+S G
Sbjct: 210 VKVWDVRVNKLLQHYQVHS-----------------GGVNCISFHPSG--NYLITASSDG 250
Query: 724 TIKVLELV 731
T+K+L+L+
Sbjct: 251 TLKILDLL 258
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 17/227 (7%)
Query: 424 VSSIEFDRDCDYFAIAGVTKKIKVYE-YDTVIQDAVDIHYPENEMTCNSKISCISWSSYH 482
V S++F D + A A K IKV+ Y ++ H + C +S
Sbjct: 105 VRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRH--------THWVRCAKFSP-D 155
Query: 483 KNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWS 542
L+ S + T+ +WD Q + + VDFN + ++GSD VK+W
Sbjct: 156 GRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQT-VKVWD 214
Query: 543 TNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKA 601
++ + + V C+ F PS Y L +D + DL + I +GH
Sbjct: 215 VRVNKLLQHYQVHSGGVNCISFHPSGNY-LITASSDGTLKILDLLEGRL-IYTLQGHTGP 272
Query: 602 VSYAKFVSGEEI-VSASTDSQLKLW--NVGKPYCLRSFKGHINEKNF 645
V F G E+ S D+Q+ LW N + +C K ++ +F
Sbjct: 273 VFTVSFSKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHF 319
Score = 38.1 bits (87), Expect = 0.029
Identities = 31/106 (29%), Positives = 57/106 (53%), Gaps = 9/106 (8%)
Query: 588 TKQPIM--VFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFK--GHINE 642
T+ P++ FKGH+ A++ +G+++ +AS D+ L LWN KP+ R+++ GH +
Sbjct: 5 TEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNF-KPHA-RAYRYVGHKDV 62
Query: 643 KNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDT--VKSV 686
V + +G+ +A S + ++ L+ FK T V+SV
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSV 108
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 72.8 bits (177), Expect = 1e-12
Identities = 49/167 (29%), Positives = 80/167 (47%), Gaps = 13/167 (7%)
Query: 476 ISWSSYHKNLLASSDYEGTVILWDGFTGQRS-------KVYQEHEKRCWSVDFNLMDPKL 528
+SW+S L S+ + TV LWD G + ++ H V ++L+ L
Sbjct: 182 LSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESL 241
Query: 529 LASGSDDAKVKLWSTNLDNSVAS---IEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYD 584
S +DD K+ +W T + + ++A A V C+ F+P S + LA G AD V +D
Sbjct: 242 FGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWD 301
Query: 585 LRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSAS--TDSQLKLWNVGK 629
LRN K + F+ H+ + + E + AS TD +L +W++ K
Sbjct: 302 LRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSK 348
Score = 38.1 bits (87), Expect = 0.029
Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKV--YQEHEKRCWSVDFNLMDPKL 528
++++C+S++ Y + +LA+ + TV LWD + K+ ++ H+ + V ++ + +
Sbjct: 273 AEVNCLSFNPYSEFILATGSADKTVALWD-LRNLKLKLHTFESHKDEIFQVHWSPHNETI 331
Query: 529 LASGSDDAKVKLW 541
LAS D ++ +W
Sbjct: 332 LASSGTDRRLNVW 344
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 71.2 bits (173), Expect = 3e-12
Identities = 53/184 (28%), Positives = 86/184 (46%), Gaps = 5/184 (2%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
L S + ++ WD + + +YQ H W +D + ASGS D +LWS +
Sbjct: 357 LLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYS-LYFASGSHDRTARLWSFDR 415
Query: 546 DNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAV-S 603
+ A+V CVKF P+S Y LA G D V + + + +F GHR V S
Sbjct: 416 TYPLRIYAGHLADVDCVKFHPNSNY-LATGSTDKTVRLWSAQQGNS-VRLFTGHRGPVLS 473
Query: 604 YAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNS 663
A +G+ + SA D +LKLW++ + +GH + + + + IA S +NS
Sbjct: 474 LAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNS 533
Query: 664 LYLY 667
+ ++
Sbjct: 534 VRVW 537
Score = 52.4 bits (124), Expect = 1e-06
Identities = 43/158 (27%), Positives = 70/158 (44%), Gaps = 5/158 (3%)
Query: 487 ASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLD 546
AS ++ T LW ++Y H V F+ + LA+GS D V+LWS
Sbjct: 400 ASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFH-PNSNYLATGSTDKTVRLWSAQQG 458
Query: 547 NSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYA 605
NSV + V + FSP+ +Y LA D + +DL + +GH ++
Sbjct: 459 NSVRLFTGHRGPVLSLAFSPNGKY-LASAGEDQRLKLWDLASGTL-YKELRGHTDNITSL 516
Query: 606 KFVSGEEIV-SASTDSQLKLWNVGKPYCLRSFKGHINE 642
F ++ SAS D+ +++W++ YC G +E
Sbjct: 517 TFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSE 554
Score = 46.6 bits (109), Expect = 8e-05
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
+ C+ + + N LA+ + TV LW G +++ H S+ F+ + K LAS
Sbjct: 429 VDCVKFHP-NSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFS-PNGKYLASA 486
Query: 533 SDDAKVKLWSTNLDNSVASIEAKA-NVCCVKFSPSSRYHLAFGCADHCVHYYDLRNT 588
+D ++KLW + N+ + FSP S +A D+ V +D+RNT
Sbjct: 487 GEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGL-IASASMDNSVRVWDIRNT 542
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/181 (22%), Positives = 72/181 (39%), Gaps = 44/181 (24%)
Query: 525 DPKLLASGSDDAKVKLWSTNL-----------------------------DNSVASIEAK 555
D KLLA+G D++ +KLWS DN+ ++
Sbjct: 279 DSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDEDDNAGTEMKIL 338
Query: 556 ANVCCVKFSP---SSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAV------SYAK 606
C +S + L D + Y+DL + ++ ++GH V Y+
Sbjct: 339 RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVL-YQGHAYPVWDLDISPYSL 397
Query: 607 FVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYL 666
+ S S D +LW+ + Y LR + GH+ + + V N +Y+A GS + ++ L
Sbjct: 398 Y-----FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRL 452
Query: 667 Y 667
+
Sbjct: 453 W 453
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 67.0 bits (162), Expect = 6e-11
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 4/175 (2%)
Query: 472 KISCISWSSYH-KNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLA 530
++ + WS + L+ S ++ TV LWD G+ ++ HE +S ++ P A
Sbjct: 113 EVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFA 172
Query: 531 SGSDDAKVKLWSTNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTK 589
S S D +++W I A +A + + + L G D + +DLRN +
Sbjct: 173 SASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVR 232
Query: 590 QPIMVFKGHRKAVSYAKF--VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINE 642
QP+ GH A+ KF + S S D ++ WN KP L H E
Sbjct: 233 QPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTE 287
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 63.9 bits (154), Expect = 5e-10
Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 4/199 (2%)
Query: 470 NSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLL 529
+++I +S+++ ++ S ++ TV++WD TG++ + H S FN D L+
Sbjct: 219 SAEIISLSFNTSGDRIITGS-FDHTVVVWDADTGRKVNILIGHCAEISSASFN-WDCSLI 276
Query: 530 ASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTK 589
+GS D KLW VA++ + + +A AD + T+
Sbjct: 277 LTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAA-TR 335
Query: 590 QPIMVFKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGL 648
+ I +GH +S F G +++ S+D ++W+ CL+ +GH +E
Sbjct: 336 KCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Query: 649 ASNGDYIACGSENNSLYLY 667
G+ + GS++N+ ++
Sbjct: 396 NYKGNIVITGSKDNTCRIW 414
Score = 61.6 bits (148), Expect = 2e-09
Identities = 53/242 (21%), Positives = 96/242 (39%), Gaps = 11/242 (4%)
Query: 488 SSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDN 547
+ Y+ T LWD +G+ + H +++ FN +A+GS D KLWS
Sbjct: 109 TGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGK 168
Query: 548 SVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAK 606
+ A + C+ F+P S +A G D +D++N ++ + +GH +
Sbjct: 169 CYHTFRGHTAEIVCLSFNPQSTL-VATGSMDTTAKLWDIQNGEE-VYTLRGHSAEIISLS 226
Query: 607 F-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLY 665
F SG+ I++ S D + +W+ + GH E + + I GS + +
Sbjct: 227 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCK 286
Query: 666 LYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTI 725
L+ K + T D D ++ + A DG + + AA +
Sbjct: 287 LWDATNGKCVATL-------TGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIA 339
Query: 726 KV 727
K+
Sbjct: 340 KL 341
Score = 57.0 bits (136), Expect = 6e-08
Identities = 48/205 (23%), Positives = 88/205 (42%), Gaps = 5/205 (2%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
+ I++++ + + +A+ ++ T LW TG+ ++ H + FN L+A+G
Sbjct: 137 VYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFN-PQSTLVATG 195
Query: 533 SDDAKVKLWSTNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQP 591
S D KLW V ++ A + + F+ S + G DH V +D +T +
Sbjct: 196 SMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGD-RIITGSFDHTVVVWD-ADTGRK 253
Query: 592 IMVFKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLAS 650
+ + GH +S A F I++ S D KLW+ C+ + GH +E
Sbjct: 254 VNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDY 313
Query: 651 NGDYIACGSENNSLYLYYKGLSKTL 675
G IA S + + ++ K +
Sbjct: 314 TGKLIATASADGTARIFSAATRKCI 338
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/199 (22%), Positives = 85/199 (42%), Gaps = 6/199 (3%)
Query: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLA 530
++I C+S++ L+A+ + T LWD G+ + H S+ FN +++
Sbjct: 178 AEIVCLSFNP-QSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRII- 235
Query: 531 SGSDDAKVKLWSTNLDNSV-ASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTK 589
+GS D V +W + V I A + F+ L G D +D N K
Sbjct: 236 TGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT-GSMDKTCKLWDATNGK 294
Query: 590 QPIMVFKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGL 648
+ GH + + F +G+ I +AS D ++++ C+ +GH E + +
Sbjct: 295 -CVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISF 353
Query: 649 ASNGDYIACGSENNSLYLY 667
G+++ GS + + ++
Sbjct: 354 NPQGNHLLTGSSDKTARIW 372
Score = 31.6 bits (70), Expect = 2.7
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 609 SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLAS-NGDYIACGSENNSLYLY 667
SG ++ S D KLW+ L + +GH N + + GD IA GS + + L+
Sbjct: 103 SGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLW 162
Query: 668 YKGLSKTLLTFKFDTVKSV 686
K TF+ T + V
Sbjct: 163 SVETGKCYHTFRGHTAEIV 181
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 63.5 bits (153), Expect = 7e-10
Identities = 59/238 (24%), Positives = 101/238 (42%), Gaps = 46/238 (19%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
++C+++S +LLAS + TV +W S V++ H SV F D + +
Sbjct: 26 VTCVNFSP-SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF-CSDGQSFVTA 83
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSR----------------------- 568
SDD VK+W+T+ + S+ N V C KFSP R
Sbjct: 84 SDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 143
Query: 569 -------------YHLAFGCA-----DHCVHYYDLRNTKQPIMVFKGHRKAVSYAKF-VS 609
+H + C D+ V +D+R T + + ++ H AV+ F S
Sbjct: 144 SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR-THRLLQHYQLHSAAVNGLSFHPS 202
Query: 610 GEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLY 667
G +++AS+DS LK+ ++ + L + GH V + G+Y A G + + ++
Sbjct: 203 GNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 260
Score = 44.7 bits (104), Expect = 3e-04
Identities = 50/209 (23%), Positives = 86/209 (41%), Gaps = 17/209 (8%)
Query: 421 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSS 480
++ V S+ F D F A K +KV+ H + + + I+ + +
Sbjct: 65 TATVRSVHFCSDGQSFVTASDDKTVKVWA----------THRQKFLFSLSQHINWVRCAK 114
Query: 481 YHKN--LLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKV 538
+ + L+ S+ + TV LWD + + Y EH VDF+ + A+G D+ V
Sbjct: 115 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNT-V 173
Query: 539 KLWSTNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKG 597
K+W + + A V + F PS Y L +D + DL + + G
Sbjct: 174 KVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY-LITASSDSTLKILDLMEGRL-LYTLHG 231
Query: 598 HR-KAVSYAKFVSGEEIVSASTDSQLKLW 625
H+ A + A +GE S +D Q+ +W
Sbjct: 232 HQGPATTVAFSRTGEYFASGGSDEQVMVW 260
Score = 31.2 bits (69), Expect = 3.6
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 17/127 (13%)
Query: 424 VSSIEFDRDCDYFAIAGVTKKIKVYEYDT--VIQDAVDIHYPENEMTCNSKISCISWSSY 481
V+ ++F A AG+ +KV++ T ++Q HY + N S+
Sbjct: 152 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ-----HYQLHSAAVNGL-------SF 199
Query: 482 HK--NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVK 539
H N L ++ + T+ + D G+ H+ +V F+ + ASG D +V
Sbjct: 200 HPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG-EYFASGGSDEQVM 258
Query: 540 LWSTNLD 546
+W +N D
Sbjct: 259 VWKSNFD 265
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 63.5 bits (153), Expect = 7e-10
Identities = 59/238 (24%), Positives = 101/238 (42%), Gaps = 46/238 (19%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
++C+++S +LLAS + TV +W S V++ H SV F D + +
Sbjct: 64 VTCVNFSP-SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF-CSDGQSFVTA 121
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSR----------------------- 568
SDD VK+W+T+ + S+ N V C KFSP R
Sbjct: 122 SDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 181
Query: 569 -------------YHLAFGCA-----DHCVHYYDLRNTKQPIMVFKGHRKAVSYAKF-VS 609
+H + C D+ V +D+R T + + ++ H AV+ F S
Sbjct: 182 SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR-THRLLQHYQLHSAAVNGLSFHPS 240
Query: 610 GEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLY 667
G +++AS+DS LK+ ++ + L + GH V + G+Y A G + + ++
Sbjct: 241 GNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 595 FKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGD 653
FKGHR AV+ F ++ +++ S S DS L +W++ F GH + V + +G
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 654 YIACGSENNSLYLYYKGLSKTLLTFKFD--TVKSV 686
+A GS + ++ ++ + F+ TV+SV
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSV 109
Score = 31.2 bits (69), Expect = 3.6
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 17/127 (13%)
Query: 424 VSSIEFDRDCDYFAIAGVTKKIKVYEYDT--VIQDAVDIHYPENEMTCNSKISCISWSSY 481
V+ ++F A AG+ +KV++ T ++Q HY + N S+
Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ-----HYQLHSAAVNGL-------SF 237
Query: 482 HK--NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVK 539
H N L ++ + T+ + D G+ H+ +V F+ + ASG D +V
Sbjct: 238 HPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG-EYFASGGSDEQVM 296
Query: 540 LWSTNLD 546
+W +N D
Sbjct: 297 VWKSNFD 303
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 63.5 bits (153), Expect = 7e-10
Identities = 59/238 (24%), Positives = 101/238 (42%), Gaps = 46/238 (19%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
++C+++S +LLAS + TV +W S V++ H SV F D + +
Sbjct: 64 VTCVNFSP-SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF-CSDGQSFVTA 121
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSR----------------------- 568
SDD VK+W+T+ + S+ N V C KFSP R
Sbjct: 122 SDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVH 181
Query: 569 -------------YHLAFGCA-----DHCVHYYDLRNTKQPIMVFKGHRKAVSYAKF-VS 609
+H + C D+ V +D+R T + + ++ H AV+ F S
Sbjct: 182 SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR-THRLLQHYQLHSAAVNGLSFHPS 240
Query: 610 GEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLY 667
G +++AS+DS LK+ ++ + L + GH V + G+Y A G + + ++
Sbjct: 241 GNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 595 FKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGD 653
FKGHR AV+ F ++ +++ S S DS L +W++ F GH + V + +G
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 654 YIACGSENNSLYLYYKGLSKTLLTFKFD--TVKSV 686
+A GS + ++ ++ + F+ TV+SV
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSV 109
Score = 31.2 bits (69), Expect = 3.6
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 17/127 (13%)
Query: 424 VSSIEFDRDCDYFAIAGVTKKIKVYEYDT--VIQDAVDIHYPENEMTCNSKISCISWSSY 481
V+ ++F A AG+ +KV++ T ++Q HY + N S+
Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQ-----HYQLHSAAVNGL-------SF 237
Query: 482 HK--NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVK 539
H N L ++ + T+ + D G+ H+ +V F+ + ASG D +V
Sbjct: 238 HPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTG-EYFASGGSDEQVM 296
Query: 540 LWSTNLD 546
+W +N D
Sbjct: 297 VWKSNFD 303
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/196 (25%), Positives = 86/196 (43%), Gaps = 5/196 (2%)
Query: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLA 530
S +S + LLA+ + V LW H SV N + +L+
Sbjct: 21 SNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPE-ELIV 79
Query: 531 SGSDDAKVKLWSTNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTK 589
+GS +++W + ++ KAN+C + F P + +A G D + +D+R K
Sbjct: 80 AGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEF-VASGSQDTNIKLWDIRR-K 137
Query: 590 QPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGL 648
+ ++GH +AV +F G+ + SA+ D +KLW++ + F GH N V
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 649 ASNGDYIACGSENNSL 664
N +A GS + ++
Sbjct: 198 HPNEYLLASGSSDRTI 213
Score = 60.8 bits (146), Expect = 4e-09
Identities = 39/154 (25%), Positives = 75/154 (48%), Gaps = 4/154 (2%)
Query: 527 KLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHYYDL 585
+LLA+G DD +V LWS N N + S+ + V V+ + +A G + +DL
Sbjct: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVA-GSQSGSIRVWDL 92
Query: 586 RNTKQPIMVFKGHRKAVSYAKFVS-GEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKN 644
K + GH+ + F GE + S S D+ +KLW++ + C+ ++GH
Sbjct: 93 EAAKI-LRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVR 151
Query: 645 FVGLASNGDYIACGSENNSLYLYYKGLSKTLLTF 678
+ + +G ++A ++++++ L+ K + F
Sbjct: 152 CLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF 185
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/69 (28%), Positives = 36/69 (52%)
Query: 609 SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYY 668
SG + + D ++ LW++ KP C+ S GH + V L + + I GS++ S+ ++
Sbjct: 32 SGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWD 91
Query: 669 KGLSKTLLT 677
+K L T
Sbjct: 92 LEAAKILRT 100
Score = 38.1 bits (87), Expect = 0.029
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
+ C+ +S K L +++D + TV LWD G+ + H V+F+ + LLASG
Sbjct: 150 VRCLRFSPDGKWLASAAD-DHTVKLWDLTAGKMMSEFPGHTGPVNVVEFH-PNEYLLASG 207
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCAD 577
S D ++ W V+ IE + V V F+P L GC D
Sbjct: 208 SSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDG-CCLYSGCQD 252
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 62.0 bits (149), Expect = 2e-09
Identities = 52/227 (22%), Positives = 94/227 (41%), Gaps = 56/227 (24%)
Query: 503 GQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCV 561
G +K+Y H W D +LL S S D K+ +W + N V +I +++ V
Sbjct: 53 GHLAKIYAMH----WGTD-----SRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC 103
Query: 562 KFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFK---GHRKAVSYAKFVSGEEIVSAS- 617
++PS Y +A G D+ Y+L+ + + V + GH +S +F+ +IV++S
Sbjct: 104 AYAPSGNY-VACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG 162
Query: 618 -----------------------------------------TDSQLKLWNVGKPYCLRSF 636
D+ KLW+V + C ++F
Sbjct: 163 DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF 222
Query: 637 KGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTV 683
GH ++ N + NG+ A GS++ + L+ + L+T+ D +
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNI 269
Score = 54.7 bits (130), Expect = 3e-07
Identities = 50/192 (26%), Positives = 82/192 (42%), Gaps = 15/192 (7%)
Query: 484 NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWST 543
N + +S + T LWD TGQ++ + H S+ D +L SG+ DA KLW
Sbjct: 155 NQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSL-APDTRLFVSGACDASAKLWDV 213
Query: 544 N---LDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHR- 599
+ E+ N C F P+ A G D +DLR Q +M +
Sbjct: 214 REGMCRQTFTGHESDINAIC--FFPNGNA-FATGSDDATCRLFDLR-ADQELMTYSHDNI 269
Query: 600 ----KAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYI 655
+VS++K SG +++ D +W+ K GH N + +G+ +G +
Sbjct: 270 ICGITSVSFSK--SGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAV 327
Query: 656 ACGSENNSLYLY 667
A GS ++ L ++
Sbjct: 328 ATGSWDSFLKIW 339
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 62.0 bits (149), Expect = 2e-09
Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 7/150 (4%)
Query: 484 NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAK--VKLW 541
N A+ +GTV +WD ++ + H VD++ L+ SGS D++ +K W
Sbjct: 215 NKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWH-PTKGLVVSGSKDSQQPIKFW 273
Query: 542 STNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRK 600
S+A++ A N V VK + + + L DH +D+RN K+ + VF+GH+K
Sbjct: 274 DPKTGQSLATLHAHKNTVMEVKLNLNGNWLLT-ASRDHLCKLFDIRNLKEELQVFRGHKK 332
Query: 601 AVSYAKFVSGEE--IVSASTDSQLKLWNVG 628
+ + E S +D L W+VG
Sbjct: 333 EATAVAWHPVHEGLFASGGSDGSLLFWHVG 362
Score = 45.1 bits (105), Expect = 2e-04
Identities = 49/220 (22%), Positives = 89/220 (40%), Gaps = 12/220 (5%)
Query: 468 TCNSKISC----ISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNL 523
T +K+ C + W+ + L+ + G LW+G T + Q H+ ++ ++
Sbjct: 113 TSTNKVKCPVFVVRWTPEGRRLVTGAS-SGEFTLWNGLTFNFETILQAHDSPVRAMTWSH 171
Query: 524 MDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYY 583
D +L + VK W +N++N K + FSP+ A D V +
Sbjct: 172 NDMWMLTA-DHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDN-KFATCSDDGTVRIW 229
Query: 584 DLRNTKQPIMVFKGHRKAVSYAKFVSGEE-IVSASTDS--QLKLWNVGKPYCLRSFKGHI 640
D + + +GH V + + +VS S DS +K W+ L + H
Sbjct: 230 DFLRCHEE-RILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHK 288
Query: 641 NEKNFVGLASNGDYIACGSENNSLYLY-YKGLSKTLLTFK 679
N V L NG+++ S ++ L+ + L + L F+
Sbjct: 289 NTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFR 328
Score = 40.0 bits (92), Expect = 0.008
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 474 SCISWSSYHKNLLASSDYEGTVILWD-GFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
+ ++W H+ L AS +G+++ W G + + HE WS+ ++ + +L SG
Sbjct: 335 TAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLG-HILCSG 393
Query: 533 SDDAKVKLWSTN 544
S+D K W+ N
Sbjct: 394 SNDHTSKFWTRN 405
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/183 (26%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
LAS ++ V+LWD +GQ ++ H S DF+ LA+GS D+ V +W +
Sbjct: 120 LASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFS-PTVNCLATGSWDSTVHIWDLRM 178
Query: 546 DNSVASIEA----KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKA 601
S +A AN+ C+ +S S LA G D +H + T ++ KGH
Sbjct: 179 VTPAVSHQALEGHSANISCLCYSASGL--LASGSWDKTIHIWK-PTTSSLLIQLKGHVTW 235
Query: 602 VSYAKFVSGEE-IVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 660
V F E + SA +K+W+ CL + KG ++ + +G + G+
Sbjct: 236 VKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAA 295
Query: 661 NNS 663
+ +
Sbjct: 296 DQT 298
Score = 61.2 bits (147), Expect = 3e-09
Identities = 52/208 (25%), Positives = 91/208 (43%), Gaps = 10/208 (4%)
Query: 484 NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWST 543
+L AS+ + TV LWD + +V + H++ +V F+ D + LASG D +V LW
Sbjct: 76 HLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFS-PDSRQLASGGWDKRVMLWDV 134
Query: 544 NLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPI--MVFKGHRK 600
+ + + ++ FSP+ LA G D VH +DLR + +GH
Sbjct: 135 QSGQMLRLLVGHRDSIQSSDFSPTVNC-LATGSWDSTVHIWDLRMVTPAVSHQALEGHSA 193
Query: 601 AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 660
+S + + + S S D + +W L KGH+ + + + ++A
Sbjct: 194 NISCLCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGY 253
Query: 661 NNSLYLYYKGLSKTLLTFKFDTVKSVLD 688
+ + ++ K L +T+K VLD
Sbjct: 254 SRMVKVWDCNTGKCL-----ETLKGVLD 276
Score = 49.3 bits (116), Expect = 1e-05
Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
Query: 563 FSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQ 621
FSP + L G D CV+ ++ R+ Q + GH V + +F G SAS D
Sbjct: 29 FSPDGQMLLT-GSEDGCVYGWETRSG-QLLWRLGGHTGPVKFCRFSPDGHLFASASCDCT 86
Query: 622 LKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLY--YKGLSKTLLTFK 679
++LW+V + CLR KGH V + + +A G + + L+ G LL
Sbjct: 87 VRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGH 146
Query: 680 FDTVKS 685
D+++S
Sbjct: 147 RDSIQS 152
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 61.6 bits (148), Expect = 2e-09
Identities = 54/193 (27%), Positives = 87/193 (45%), Gaps = 11/193 (5%)
Query: 480 SYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFN-----LMDPK--LLASG 532
S + +LA++ + G LW + H ++ F+ +DPK LAS
Sbjct: 240 SPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASC 299
Query: 533 SDDAKVKLWSTNLDNSVASIEAKA-NVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQP 591
+ D VKLWS + D VA IE V V + PS R+ L C D +DL ++
Sbjct: 300 AADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRF-LGTTCYDRSWRLWDLE-AQEE 357
Query: 592 IMVFKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLAS 650
I+ +GH V F G + D+ ++W++ C+ +GH+ E + +
Sbjct: 358 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSP 417
Query: 651 NGDYIACGSENNS 663
NG +IA GS +N+
Sbjct: 418 NGYHIATGSGDNT 430
Score = 31.6 bits (70), Expect = 2.7
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
++ + + H N L + Y+ T +W K HE + +D + D +L+A+
Sbjct: 452 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDIS-SDGQLIATC 510
Query: 533 SDDAKVKLW 541
S D KLW
Sbjct: 511 SYDRTFKLW 519
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 61.2 bits (147), Expect = 3e-09
Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 12/195 (6%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
I+C+ + N + S + T+ +W TG+ + H WS + M ++ SG
Sbjct: 266 ITCLQFCG---NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS---SQMRDNIIISG 319
Query: 533 SDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPI 592
S D +K+W+ + ++ + V+ + G D + +D+ T Q +
Sbjct: 320 STDRTLKVWNAETGECIHTLYGHTST--VRCMHLHEKRVVSGSRDATLRVWDIE-TGQCL 376
Query: 593 MVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNG 652
V GH AV ++ G +VS + D +K+W+ CL + +GH N L +G
Sbjct: 377 HVLMGHVAAVRCVQY-DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN--RVYSLQFDG 433
Query: 653 DYIACGSENNSLYLY 667
++ GS + S+ ++
Sbjct: 434 IHVVSGSLDTSIRVW 448
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/257 (21%), Positives = 107/257 (41%), Gaps = 34/257 (13%)
Query: 478 WSSYHK-NLLASSDYEGTVILWDGFTGQRSKVYQEHEK--RCWSVDFNLMDPKLLASGSD 534
WSS + N++ S + T+ +W+ TG+ H RC + K + SGS
Sbjct: 307 WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMH-----LHEKRVVSGSR 361
Query: 535 DAKVKLWSTNLDNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIM 593
DA +++W + + A V CV++ + G D V +D T+ +
Sbjct: 362 DATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR---RVVSGAYDFMVKVWD-PETETCLH 417
Query: 594 VFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGD 653
+GH V +F G +VS S D+ +++W+V C+ + GH + G+ +
Sbjct: 418 TLQGHTNRVYSLQF-DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH--QSLTSGMELKDN 474
Query: 654 YIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGES 713
+ G+ ++++ ++ + L T + N+ SAV
Sbjct: 475 ILVSGNADSTVKIWDIKTGQCLQTLQ---------------GPNKHQSAVTCLQF---NK 516
Query: 714 NVLIAANSQGTIKVLEL 730
N +I ++ GT+K+ +L
Sbjct: 517 NFVITSSDDGTVKLWDL 533
Score = 36.6 bits (83), Expect = 0.085
Identities = 19/46 (41%), Positives = 23/46 (50%)
Query: 594 VFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639
V KGH V G IVS S D+ LK+W+ CLR+ GH
Sbjct: 257 VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH 302
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 61.2 bits (147), Expect = 3e-09
Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 12/195 (6%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
I+C+ + N + S + T+ +W TG+ + H WS + M ++ SG
Sbjct: 384 ITCLQFCG---NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS---SQMRDNIIISG 437
Query: 533 SDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPI 592
S D +K+W+ + ++ + V+ + G D + +D+ T Q +
Sbjct: 438 STDRTLKVWNAETGECIHTLYGHTST--VRCMHLHEKRVVSGSRDATLRVWDIE-TGQCL 494
Query: 593 MVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNG 652
V GH AV ++ G +VS + D +K+W+ CL + +GH N L +G
Sbjct: 495 HVLMGHVAAVRCVQY-DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN--RVYSLQFDG 551
Query: 653 DYIACGSENNSLYLY 667
++ GS + S+ ++
Sbjct: 552 IHVVSGSLDTSIRVW 566
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/257 (21%), Positives = 107/257 (41%), Gaps = 34/257 (13%)
Query: 478 WSSYHK-NLLASSDYEGTVILWDGFTGQRSKVYQEHEK--RCWSVDFNLMDPKLLASGSD 534
WSS + N++ S + T+ +W+ TG+ H RC + K + SGS
Sbjct: 425 WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMH-----LHEKRVVSGSR 479
Query: 535 DAKVKLWSTNLDNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIM 593
DA +++W + + A V CV++ + G D V +D T+ +
Sbjct: 480 DATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR---RVVSGAYDFMVKVWD-PETETCLH 535
Query: 594 VFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGD 653
+GH V +F G +VS S D+ +++W+V C+ + GH + G+ +
Sbjct: 536 TLQGHTNRVYSLQF-DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH--QSLTSGMELKDN 592
Query: 654 YIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGES 713
+ G+ ++++ ++ + L T + N+ SAV
Sbjct: 593 ILVSGNADSTVKIWDIKTGQCLQTLQ---------------GPNKHQSAVTCLQF---NK 634
Query: 714 NVLIAANSQGTIKVLEL 730
N +I ++ GT+K+ +L
Sbjct: 635 NFVITSSDDGTVKLWDL 651
Score = 36.6 bits (83), Expect = 0.085
Identities = 19/46 (41%), Positives = 23/46 (50%)
Query: 594 VFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639
V KGH V G IVS S D+ LK+W+ CLR+ GH
Sbjct: 375 VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH 420
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 61.2 bits (147), Expect = 3e-09
Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 12/195 (6%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
I+C+ + N + S + T+ +W TG+ + H WS + M ++ SG
Sbjct: 304 ITCLQFCG---NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS---SQMRDNIIISG 357
Query: 533 SDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPI 592
S D +K+W+ + ++ + V+ + G D + +D+ T Q +
Sbjct: 358 STDRTLKVWNAETGECIHTLYGHTST--VRCMHLHEKRVVSGSRDATLRVWDIE-TGQCL 414
Query: 593 MVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNG 652
V GH AV ++ G +VS + D +K+W+ CL + +GH N L +G
Sbjct: 415 HVLMGHVAAVRCVQY-DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN--RVYSLQFDG 471
Query: 653 DYIACGSENNSLYLY 667
++ GS + S+ ++
Sbjct: 472 IHVVSGSLDTSIRVW 486
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/257 (21%), Positives = 107/257 (41%), Gaps = 34/257 (13%)
Query: 478 WSSYHK-NLLASSDYEGTVILWDGFTGQRSKVYQEHEK--RCWSVDFNLMDPKLLASGSD 534
WSS + N++ S + T+ +W+ TG+ H RC + K + SGS
Sbjct: 345 WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMH-----LHEKRVVSGSR 399
Query: 535 DAKVKLWSTNLDNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIM 593
DA +++W + + A V CV++ + G D V +D T+ +
Sbjct: 400 DATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR---RVVSGAYDFMVKVWD-PETETCLH 455
Query: 594 VFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGD 653
+GH V +F G +VS S D+ +++W+V C+ + GH + G+ +
Sbjct: 456 TLQGHTNRVYSLQF-DGIHVVSGSLDTSIRVWDVETGNCIHTLTGH--QSLTSGMELKDN 512
Query: 654 YIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGES 713
+ G+ ++++ ++ + L T + N+ SAV
Sbjct: 513 ILVSGNADSTVKIWDIKTGQCLQTLQ---------------GPNKHQSAVTCLQF---NK 554
Query: 714 NVLIAANSQGTIKVLEL 730
N +I ++ GT+K+ +L
Sbjct: 555 NFVITSSDDGTVKLWDL 571
Score = 36.6 bits (83), Expect = 0.085
Identities = 19/46 (41%), Positives = 23/46 (50%)
Query: 594 VFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639
V KGH V G IVS S D+ LK+W+ CLR+ GH
Sbjct: 295 VLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGH 340
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 61.2 bits (147), Expect = 3e-09
Identities = 64/271 (23%), Positives = 106/271 (39%), Gaps = 40/271 (14%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
I + W+ N + S+ + T I+WD TG+ + + H VD+ + AS
Sbjct: 279 IFALKWNK-KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ--NNMTFASC 335
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADH------------C 579
S D + + D+ V + + N V +K+ PS L C+D C
Sbjct: 336 STDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM--LLASCSDDMTLKIWSMKQDAC 393
Query: 580 VHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639
VH DL+ + I K + + S + SAS DS ++LW+V + C + H
Sbjct: 394 VH--DLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH 451
Query: 640 INEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEF 699
V + +G Y+A GS + Y++ L + + +
Sbjct: 452 QEPVYSVAFSPDGKYLASGSFDK--YVHIWNTQSGSLVHSYQGTGGIFE----------- 498
Query: 700 VSAVCWRALPDGESNVLIAANSQGTIKVLEL 730
VCW A D A+ S G++ VL+L
Sbjct: 499 ---VCWNARGDKVG----ASASDGSVCVLDL 522
Score = 30.4 bits (67), Expect = 6.1
Identities = 51/245 (20%), Positives = 92/245 (37%), Gaps = 52/245 (21%)
Query: 505 RSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS 564
++ V + HE + +N + LLASGS D+ ++W+ N +++ S + C +
Sbjct: 171 KATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 229
Query: 565 ---PSSR-----------YHLAFGCADHCVHYY--------DLRNTKQPIMVFKGHRKAV 602
PS++ LA G D + L K PI K ++K
Sbjct: 230 HDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKK-- 287
Query: 603 SYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENN 662
G ++SA D +W+ + F H V +N + +C S +
Sbjct: 288 -------GNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASC-STDM 339
Query: 663 SLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQ 722
+++ G + TF + TNE V+A+ W D +L + +
Sbjct: 340 CIHVCRLGCDHPVKTF--------------QGHTNE-VNAIKW----DPSGMLLASCSDD 380
Query: 723 GTIKV 727
T+K+
Sbjct: 381 MTLKI 385
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 61.2 bits (147), Expect = 3e-09
Identities = 64/271 (23%), Positives = 106/271 (39%), Gaps = 40/271 (14%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
I + W+ N + S+ + T I+WD TG+ + + H VD+ + AS
Sbjct: 279 IFALKWNK-KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ--NNMTFASC 335
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADH------------C 579
S D + + D+ V + + N V +K+ PS L C+D C
Sbjct: 336 STDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM--LLASCSDDMTLKIWSMKQDAC 393
Query: 580 VHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639
VH DL+ + I K + + S + SAS DS ++LW+V + C + H
Sbjct: 394 VH--DLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH 451
Query: 640 INEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEF 699
V + +G Y+A GS + Y++ L + + +
Sbjct: 452 QEPVYSVAFSPDGKYLASGSFDK--YVHIWNTQSGSLVHSYQGTGGIFE----------- 498
Query: 700 VSAVCWRALPDGESNVLIAANSQGTIKVLEL 730
VCW A D A+ S G++ VL+L
Sbjct: 499 ---VCWNARGDKVG----ASASDGSVCVLDL 522
Score = 30.4 bits (67), Expect = 6.1
Identities = 51/245 (20%), Positives = 92/245 (37%), Gaps = 52/245 (21%)
Query: 505 RSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS 564
++ V + HE + +N + LLASGS D+ ++W+ N +++ S + C +
Sbjct: 171 KATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 229
Query: 565 ---PSSR-----------YHLAFGCADHCVHYY--------DLRNTKQPIMVFKGHRKAV 602
PS++ LA G D + L K PI K ++K
Sbjct: 230 HDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKK-- 287
Query: 603 SYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENN 662
G ++SA D +W+ + F H V +N + +C S +
Sbjct: 288 -------GNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASC-STDM 339
Query: 663 SLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQ 722
+++ G + TF + TNE V+A+ W D +L + +
Sbjct: 340 CIHVCRLGCDHPVKTF--------------QGHTNE-VNAIKW----DPSGMLLASCSDD 380
Query: 723 GTIKV 727
T+K+
Sbjct: 381 MTLKI 385
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 61.2 bits (147), Expect = 3e-09
Identities = 64/271 (23%), Positives = 106/271 (39%), Gaps = 40/271 (14%)
Query: 473 ISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 532
I + W+ N + S+ + T I+WD TG+ + + H VD+ + AS
Sbjct: 279 IFALKWNK-KGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ--NNMTFASC 335
Query: 533 SDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYHLAFGCADH------------C 579
S D + + D+ V + + N V +K+ PS L C+D C
Sbjct: 336 STDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGM--LLASCSDDMTLKIWSMKQDAC 393
Query: 580 VHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639
VH DL+ + I K + + S + SAS DS ++LW+V + C + H
Sbjct: 394 VH--DLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH 451
Query: 640 INEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEF 699
V + +G Y+A GS + Y++ L + + +
Sbjct: 452 QEPVYSVAFSPDGKYLASGSFDK--YVHIWNTQSGSLVHSYQGTGGIFE----------- 498
Query: 700 VSAVCWRALPDGESNVLIAANSQGTIKVLEL 730
VCW A D A+ S G++ VL+L
Sbjct: 499 ---VCWNARGDKVG----ASASDGSVCVLDL 522
Score = 30.4 bits (67), Expect = 6.1
Identities = 51/245 (20%), Positives = 92/245 (37%), Gaps = 52/245 (21%)
Query: 505 RSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS 564
++ V + HE + +N + LLASGS D+ ++W+ N +++ S + C +
Sbjct: 171 KATVLRGHESEVFICAWNPVSD-LLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGG 229
Query: 565 ---PSSR-----------YHLAFGCADHCVHYY--------DLRNTKQPIMVFKGHRKAV 602
PS++ LA G D + L K PI K ++K
Sbjct: 230 HDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNKK-- 287
Query: 603 SYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENN 662
G ++SA D +W+ + F H V +N + +C S +
Sbjct: 288 -------GNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASC-STDM 339
Query: 663 SLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQ 722
+++ G + TF + TNE V+A+ W D +L + +
Sbjct: 340 CIHVCRLGCDHPVKTF--------------QGHTNE-VNAIKW----DPSGMLLASCSDD 380
Query: 723 GTIKV 727
T+K+
Sbjct: 381 MTLKI 385
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 60.8 bits (146), Expect = 4e-09
Identities = 52/227 (22%), Positives = 92/227 (40%), Gaps = 56/227 (24%)
Query: 503 GQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCV 561
G +K+Y H W D +LL S S D K+ +W + N + +I +++ V
Sbjct: 53 GHLAKIYAMH----WGYD-----SRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC 103
Query: 562 KFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFK---GHRKAVSYAKFVSGEEIVSAS- 617
++PS Y +A G D+ Y+L+ + + V + GH +S +F+ +IV++S
Sbjct: 104 AYAPSGNY-VACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSG 162
Query: 618 -----------------------------------------TDSQLKLWNVGKPYCLRSF 636
D+ KLW++ C +SF
Sbjct: 163 DTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSF 222
Query: 637 KGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTV 683
GH+++ N V NG A GS++ + L+ + LL + D +
Sbjct: 223 TGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNI 269
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 9/187 (4%)
Query: 486 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNL 545
+ +S + T LWD T Q++ + H S+ + D + SG+ DA KLW
Sbjct: 157 IVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLS-PDMRTFVSGACDASSKLWDIRD 215
Query: 546 DNSVASIEAK-ANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAV-- 602
S +++ V F P+ Y A G D +DLR ++ ++ H +
Sbjct: 216 GMCRQSFTGHVSDINAVSFFPNG-YAFATGSDDATCRLFDLRADQE--LLLYSHDNIICG 272
Query: 603 --SYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSE 660
S A SG +++ D +W+ K GH N + +G+ +G +A GS
Sbjct: 273 ITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 661 NNSLYLY 667
++ L ++
Sbjct: 333 DSFLRIW 339
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 60.8 bits (146), Expect = 4e-09
Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 32/222 (14%)
Query: 430 DRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISC-------------- 475
D +Y A+ +T I+V++ D V D++ E T SK+S
Sbjct: 202 DSTGNYIAVGNMTPVIEVWDLDIV--DSL-----EPVFTLGSKLSKKKKKKGKKSSSAEG 254
Query: 476 -------ISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKL 528
+SW+ +N+LAS+ + TVILWD G+ + H + ++ F+ + +
Sbjct: 255 HTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQT 314
Query: 529 LASGSDDAKVKLWS-TNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRN 587
L SGS D V L+ + D S + V ++ S H D V+ D R+
Sbjct: 315 LISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARS 374
Query: 588 TKQPIMVFKGHRKAVSYAKFVSGEE--IVSASTDSQLKLWNV 627
K PI H +S S + +V+AS D +K+W++
Sbjct: 375 DK-PIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,972,840
Number of Sequences: 37866
Number of extensions: 1342079
Number of successful extensions: 14284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 419
Number of HSP's successfully gapped in prelim test: 622
Number of HSP's that attempted gapping in prelim test: 9972
Number of HSP's gapped (non-prelim): 3517
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.