BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo sapiens] (800 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H... 1614 0.0 gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho... 1037 0.0 gi|239755159 PREDICTED: similar to tubulin tyrosine ligase-like ... 447 e-125 gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo... 225 1e-58 gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo... 218 2e-56 gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ... 205 1e-52 gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo... 164 3e-40 gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ... 161 2e-39 gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ... 138 2e-32 gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ... 123 8e-28 gi|24308516 tubulin tyrosine ligase [Homo sapiens] 81 4e-15 gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ... 79 2e-14 gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo... 72 2e-12 gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo... 71 5e-12 gi|194239681 tubulin tyrosine ligase-like family, member 10 isof... 62 2e-09 gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo... 62 3e-09 gi|73476377 LBXCOR1 homolog [Homo sapiens] 52 3e-06 gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens] 47 5e-05 gi|194239678 tubulin tyrosine ligase-like family, member 10 isof... 47 9e-05 gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 44 5e-04 gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 44 6e-04 gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo... 44 6e-04 gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 43 0.001 gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 41 0.004 gi|19111150 angiomotin isoform 2 [Homo sapiens] 41 0.005 gi|166064029 angiomotin isoform 1 [Homo sapiens] 41 0.005 gi|239755810 PREDICTED: hypothetical protein [Homo sapiens] 40 0.009 gi|239750310 PREDICTED: hypothetical protein [Homo sapiens] 40 0.009 gi|239744621 PREDICTED: hypothetical protein [Homo sapiens] 40 0.009 gi|24497554 homeobox A13 [Homo sapiens] 40 0.011 >gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo sapiens] Length = 800 Score = 1614 bits (4179), Expect = 0.0 Identities = 800/800 (100%), Positives = 800/800 (100%) Query: 1 MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60 MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG Sbjct: 1 MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60 Query: 61 CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120 CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA Sbjct: 61 CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120 Query: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP Sbjct: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180 Query: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL Sbjct: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240 Query: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE Sbjct: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300 Query: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL Sbjct: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360 Query: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP Sbjct: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420 Query: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII Sbjct: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480 Query: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRI 540 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRI Sbjct: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRI 540 Query: 541 EHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALD 600 EHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALD Sbjct: 541 EHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALD 600 Query: 601 GELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGP 660 GELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGP Sbjct: 601 GELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGP 660 Query: 661 TGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQR 720 TGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQR Sbjct: 661 TGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQR 720 Query: 721 KFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGD 780 KFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGD Sbjct: 721 KFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGD 780 Query: 781 NPPPRTSCANKLSHPRHTLS 800 NPPPRTSCANKLSHPRHTLS Sbjct: 781 NPPPRTSCANKLSHPRHTLS 800 >gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo sapiens] Length = 538 Score = 1037 bits (2681), Expect = 0.0 Identities = 513/514 (99%), Positives = 514/514 (100%) Query: 1 MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60 MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG Sbjct: 1 MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60 Query: 61 CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120 CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA Sbjct: 61 CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120 Query: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP Sbjct: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180 Query: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL Sbjct: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240 Query: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE Sbjct: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300 Query: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL Sbjct: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360 Query: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP Sbjct: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420 Query: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII Sbjct: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480 Query: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQI 514 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQ+ Sbjct: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQV 514 >gi|239755159 PREDICTED: similar to tubulin tyrosine ligase-like family, member 11 a [Homo sapiens] Length = 259 Score = 447 bits (1149), Expect = e-125 Identities = 216/219 (98%), Positives = 219/219 (100%) Query: 582 ENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDR 641 +++SQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDR Sbjct: 41 QSRSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDR 100 Query: 642 MANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQR 701 MANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQR Sbjct: 101 MANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQR 160 Query: 702 DSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGR 761 DSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGR Sbjct: 161 DSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGR 220 Query: 762 PPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS 800 PPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS Sbjct: 221 PPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS 259 >gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo sapiens] Length = 459 Score = 225 bits (574), Expect = 1e-58 Identities = 130/329 (39%), Positives = 190/329 (57%), Gaps = 34/329 (10%) Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDP 330 ++N FPGMTE+ RK L+R + M L+P EYN +PR+W LP ++ F + + K Sbjct: 140 KINHFPGMTEICRKDLLARNLNRMYKLYPSEYNIFPRTWCLPADYGDFQSYGRQRK---- 195 Query: 331 SWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRL 390 T+I KPD GCQG GI++ ++P +I+ + Q+YI KPLLID KFD+R+ Sbjct: 196 --ARTYICKPDSGCQGRGIFITRNPREIK-----PGEHMICQQYISKPLLIDGFKFDMRV 248 Query: 391 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSA 450 YVL+ S DPL I+ ++GL+RF T PY EP+ NL + MHLTNY++N H+ NF+ Sbjct: 249 YVLITSCDPLRIFTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVR--DG 306 Query: 451 STGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPT 510 + GSKR S++ L + ++W DI ++IKT+I+ L+ Y++ P G T Sbjct: 307 AVGSKRKLSTLNIWLQEHSYNPGELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGT 366 Query: 511 --CFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIR 568 CF+ILGFDILL LKP LLEVN +PS + S +D+EVK A++ Sbjct: 367 CACFEILGFDILLDHKLKPWLLEVNHSPSFTTD--------------SCLDQEVKDALLC 412 Query: 569 DTLRLM-----DPLKKKRENQSQQLEKPF 592 D + L+ D K E++ + E+ F Sbjct: 413 DAMTLVNLRGCDKRKVMEEDKRRVKERLF 441 >gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform 1 [Homo sapiens] Length = 891 Score = 218 bits (554), Expect = 2e-56 Identities = 121/305 (39%), Positives = 175/305 (57%), Gaps = 27/305 (8%) Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDP 330 ++N FPGM+E+ RK L+R + M +FP+++ F+PR+W LP ++ + K+ Sbjct: 161 KINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNK-- 218 Query: 331 SWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRL 390 T+I KPD GCQG GI++ + +I+ + Q YI KP +ID KFD+R+ Sbjct: 219 ----TYICKPDSGCQGKGIFITRTVKEIK-----PGEDMICQLYISKPFIIDGFKFDLRI 269 Query: 391 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSA 450 YVL+ S DPL I++ +GL+RF T Y P NL I MHLTNYS+N HS NF S A Sbjct: 270 YVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNF--SRDA 327 Query: 451 STGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPT 510 +GSKR S+ L +++++W DI V+IKT+I+ P ++ Y + P Sbjct: 328 HSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSA 387 Query: 511 CFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDT 570 CF+ILGFDILL LKP LLEVN +PS + S +D+EVK ++ DT Sbjct: 388 CFEILGFDILLDHKLKPWLLEVNHSPSF--------------STDSRLDKEVKDGLLYDT 433 Query: 571 LRLMD 575 L L++ Sbjct: 434 LVLIN 438 >gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo sapiens] Length = 887 Score = 205 bits (522), Expect = 1e-52 Identities = 136/410 (33%), Positives = 209/410 (50%), Gaps = 29/410 (7%) Query: 185 PVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKE 244 P +G+ P D S ++ T+ ++ A T + +++ I ++ + + Sbjct: 5 PQEGVIQGPSPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMK 64 Query: 245 FPFGRRLPCDIYWHGVSFHDNDIFSGQ----VNKFPGMTEMVRKITLSRAVRTMQNLFPE 300 P ++ W + I Q +N FPGM E+ RK L+R + M P Sbjct: 65 TP-DEDETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPL 123 Query: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360 +Y F PR+WI P E+ F V+ +K + TFIVKP G G GI LI++ + Sbjct: 124 DYTFVPRTWIFPAEYTQFQNYVKELKKKRK--QKTFIVKPANGAMGHGISLIRNGDKLPS 181 Query: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420 L +VQEYI KP L++ KFD+R+Y+L+ S DPL+I++ DGL R TE Y P Sbjct: 182 QDHL-----IVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPP 236 Query: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480 NL +++MHLTNYS+N H+ +F ++ + GSKR+ L + D+ K WSDI Sbjct: 237 NESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDIS 296 Query: 481 SVVIKTVIALTPELKVFYQSDIPTGRPG--PTCFQILGFDILLMKNLKPILLEVNANPSM 538 +V+KT+I P + Y+ P PG CF++LGFDILL + LKP LLE+N PS Sbjct: 297 ELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSF 356 Query: 539 RIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMD-PLKKKRENQSQQ 587 + + +D +VK V+ + L+L++ KR N ++Q Sbjct: 357 GTDQK--------------IDYDVKRGVLLNALKLLNIRTSDKRRNLAKQ 392 >gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo sapiens] Length = 1199 Score = 164 bits (415), Expect = 3e-40 Identities = 112/306 (36%), Positives = 169/306 (55%), Gaps = 32/306 (10%) Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLF-PEEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329 ++N FPG ++ RK L R + MQ+ F +E++F+P+S+ILP + +L + K + Sbjct: 658 KLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKL------LRKAWE 711 Query: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389 S + +IVKP +G GI +I S + + RP +VQ Y+ KP LI KFD+R Sbjct: 712 SSSRQKWIVKPPASARGIGIQVIHKWSQLP-----KRRPLLVQRYLHKPYLISGSKFDLR 766 Query: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHS-- 447 +YV + S DPL IY+ DGL RF + Y P+ K+L FMHLTNYS+N + + + Sbjct: 767 IYVYVTSYDPLRIYLFSDGLVRFASCKY-SPSMKSLGNKFMHLTNYSVNKKNAEYQANAD 825 Query: 448 DSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRP 507 + A G K ++ LS KGV+ +W I VV+KT+I+ P + + + R Sbjct: 826 EMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYV---RR 882 Query: 508 GPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVI 567 +C ++ GFDI+L +NLKP +LEVN +PS+ H SP +D +K +I Sbjct: 883 PYSCHELFGFDIMLDENLKPWVLEVNISPSL-----HSSSP---------LDISIKGQMI 928 Query: 568 RDTLRL 573 RD L L Sbjct: 929 RDLLNL 934 >gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo sapiens] Length = 1281 Score = 161 bits (408), Expect = 2e-39 Identities = 100/272 (36%), Positives = 155/272 (56%), Gaps = 20/272 (7%) Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFP-EEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329 +VN FP E+ RK L + + MQ+ + ++ P++++LP E+ F KD Sbjct: 118 KVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYS--KDRG 175 Query: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389 P +IVKP +G G+YLI +P+ I L + +V YI PLLID KFD+R Sbjct: 176 P-----WIVKPVASSRGRGVYLINNPNQISLEENI-----LVSRYINNPLLIDDFKFDVR 225 Query: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDS 449 LYVL+ S DPL IY+ ++GL+RF T Y + KN+ FMHLTNYS+N SG+++ D Sbjct: 226 LYVLVTSYDPLVIYLYEEGLARFATVRYDQGA-KNIRNQFMHLTNYSVNKKSGDYVSCDD 284 Query: 450 AST---GSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGR 506 G+K + S++L L +G D + + + ++IKT+I+ + ++ +P Sbjct: 285 PEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVP--- 341 Query: 507 PGPTCFQILGFDILLMKNLKPILLEVNANPSM 538 +CF++ GFD+L+ LKP LLEVN +PS+ Sbjct: 342 HRSSCFELYGFDVLIDSTLKPWLLEVNLSPSL 373 >gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo sapiens] Length = 592 Score = 138 bits (348), Expect = 2e-32 Identities = 95/298 (31%), Positives = 149/298 (50%), Gaps = 33/298 (11%) Query: 254 DIYWHGVSFHDNDIFS----GQVNKFPGMTEMVRKITLSRAVRTMQNLFPEE-YNFYPRS 308 ++YW SF + S Q+N PG T++ RK L++ ++ M+ ++ Y F P + Sbjct: 122 NLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLT 181 Query: 309 WILPDEFQLFVAQV----QMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTL 364 +++P+++ FVA+ QM+ W I KP +G GI + D D + Sbjct: 182 FVMPNDYTKFVAEYFQERQMLGTKHSYW----ICKPAELSRGRGILIFSDFKDF-----I 232 Query: 365 QSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKN 424 +VQ+YI PLLI + K D+R+YV + PL IY+ ++GL RF TE + N Sbjct: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSN 289 Query: 425 LHRIFMHLTNYSLNIHSGNFIH-SDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483 L + HLTN S+N ++ + G K T S L S VD +W I +V Sbjct: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349 Query: 484 IKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIE 541 I T++A+ P + CF++ GFDIL+ NLKP LLEVN +P++ ++ Sbjct: 350 ILTILAIAPSVPF-----------AANCFELFGFDILIDDNLKPWLLEVNYSPALTLD 396 >gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo sapiens] Length = 423 Score = 123 bits (308), Expect = 8e-28 Identities = 96/332 (28%), Positives = 155/332 (46%), Gaps = 63/332 (18%) Query: 272 VNKFPGMTEMVRKITLSRAVRTMQNLFPEE---------------YNFYPRSWILPDEFQ 316 VN FP E+ RK + + ++ + +E +F P +++LP ++ Sbjct: 62 VNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYN 121 Query: 317 LFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIR----------LAGTLQS 366 LFV + + S T+I+KP G QG GI+LI S I+ Sbjct: 122 LFVEEFRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK 175 Query: 367 RPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426 V+ YI PLLI KFD+RLYVL+ + PL Y+ K G RFCT Y P+ L Sbjct: 176 EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKY-TPSTSELD 234 Query: 427 RIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRL-SSKGVDI-KKVWSDIISVVI 484 +F+HLTN ++ H ++ H G K T S++ L S++G ++ K++ +I +++ Sbjct: 235 NMFVHLTNVAIQKHGEDYNHIH----GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIV 290 Query: 485 KTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEH 544 +++ A+ P + CF+ G+DI++ LKP L+EVNA+PS+ + Sbjct: 291 QSLKAVAPVM-----------NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTAN 339 Query: 545 ELSPGVFENVPSLVDEEVKVAVIRDTLRLMDP 576 D +K +I DTL + P Sbjct: 340 --------------DRILKYNLINDTLNIAVP 357 >gi|24308516 tubulin tyrosine ligase [Homo sapiens] Length = 377 Score = 80.9 bits (198), Expect = 4e-15 Identities = 78/310 (25%), Positives = 137/310 (44%), Gaps = 48/310 (15%) Query: 272 VNKFPGMTEMVRKITLSRAVRTMQNL------FPEEYNFYPRSWILP------------- 312 VN + G ++ RK +L + ++T L FPE Y YP + P Sbjct: 62 VNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPIS 121 Query: 313 ----DEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRP 368 DE + F+A K+D +I K G +G+GI + + S++ Q + Sbjct: 122 NSRTDEREFFLASYNRKKEDGEG--NVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179 Query: 369 AVVQEYICKPLLIDK--LKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426 V+Q+Y+ PLL++ KFDIR +VL+ IY+ ++G+ R +EPY N Sbjct: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYHVD---NFQ 234 Query: 427 RIFMHLTNYSLNI-HSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIK 485 HLTN+ + +S N+ + + + F+ L + ++ + I ++ Sbjct: 235 DKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLE-SSILLQIKHIIRN 293 Query: 486 TVIALTPELKVF---YQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEH 542 ++++ P + YQS FQ+ GFD ++ + LK L+EVN P+ + Sbjct: 294 CLLSVEPAISTKHLPYQS-----------FQLFGFDFMVDEELKVWLIEVNGAPACAQKL 342 Query: 543 EHELSPGVFE 552 EL G+ + Sbjct: 343 YAELCQGIVD 352 >gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo sapiens] Length = 439 Score = 79.0 bits (193), Expect = 2e-14 Identities = 87/337 (25%), Positives = 153/337 (45%), Gaps = 65/337 (19%) Query: 253 CDIYWHGVSF-HDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEY--------N 303 CD+ W +F H +++ F E+ RK + + ++ + E + Sbjct: 78 CDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCD 137 Query: 304 FYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDI----- 358 F+P+++ +P E+ LFV + + K+ +W I+KP QG GI+L + DI Sbjct: 138 FFPKTFEMPCEYHLFVEEFR--KNPGITW----IMKPVARSQGKGIFLFRRLKDIVDWRK 191 Query: 359 ------RLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRF 412 + V Q YI P LI KFD+R+YVL+ S+ Sbjct: 192 DTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSV--------------- 236 Query: 413 CTEPYQEPTPKNLHRIF-MHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSK-GV 470 + E + HR +HLTN ++ S ++ G K T L+SK G Sbjct: 237 ----FAECLLWSGHRRQDVHLTNVAVQKTSPDY----HPKKGCKWTLQRFRQYLASKHGP 288 Query: 471 D-IKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPIL 529 + ++ ++ DI ++ +K++ ++ KV CF++ G+DIL+ ++LKP L Sbjct: 289 EAVETLFRDIDNIFVKSLQSVQ---KVIISDK--------HCFELYGYDILIDQDLKPWL 337 Query: 530 LEVNANPSMRI--EHEHELSPGVFENVPSLVDEEVKV 564 LEVNA+PS+ + ++EL + E+ +VD E ++ Sbjct: 338 LEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARL 374 >gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform 2 [Homo sapiens] Length = 584 Score = 72.4 bits (176), Expect = 2e-12 Identities = 43/120 (35%), Positives = 64/120 (53%), Gaps = 14/120 (11%) Query: 456 RTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQIL 515 R S+ L +++++W DI V+IKT+I+ P ++ Y + P CF+IL Sbjct: 26 RKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEIL 85 Query: 516 GFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMD 575 GFDILL LKP LLEVN +PS + S +D+EVK ++ DTL L++ Sbjct: 86 GFDILLDHKLKPWLLEVNHSPSF--------------STDSRLDKEVKDGLLYDTLVLIN 131 >gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo sapiens] Length = 772 Score = 70.9 bits (172), Expect = 5e-12 Identities = 63/230 (27%), Positives = 106/230 (46%), Gaps = 21/230 (9%) Query: 314 EFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSD-IRLAG----TLQSRP 368 + Q V Q+ M D + +IVKP +G GI + + ++L ++ Sbjct: 263 QLQAVVPQIDMEGD-----RNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGK 317 Query: 369 AVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRI 428 VVQ+YI +PLLI KFD+R + L+ +PL ++ +D RF T+P+ + KNL Sbjct: 318 WVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF---SLKNLDN- 373 Query: 429 FMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVI 488 +HL N S+ H N H +SS + + + WS II +K + Sbjct: 374 SVHLCNNSIQKHLENSCHRHPL-LPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAV 432 Query: 489 ALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSM 538 Q+ T + F++ G D + ++ +P L+E+NA+P+M Sbjct: 433 IHA------LQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTM 476 >gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform 1 [Homo sapiens] Length = 673 Score = 62.4 bits (150), Expect = 2e-09 Identities = 76/294 (25%), Positives = 117/294 (39%), Gaps = 53/294 (18%) Query: 291 VRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIY 350 V M+ FPE Y L E + F + D+ W I KP QG GI+ Sbjct: 278 VLRMEEFFPETYRLD-----LKHEREAFFT----LFDETQIW----ICKPTASNQGKGIF 324 Query: 351 LIKDPSDIRL----AGTLQSRPA------------VVQEYICKPLLIDKLKFDIRLYVLL 394 L+++ ++ +++ P VVQ YI PLL+D KFD+R Y+L+ Sbjct: 325 LLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLI 384 Query: 395 KSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGS 454 P I+ G +R Y +P +L HLTN + S ++ + S Sbjct: 385 ACTTPYMIFFG-HGYARLTLSLY-DPHSSDLGG---HLTNQFMQKKSPLYMLLKEHTVWS 439 Query: 455 KRTFSSILCRLSSKGVDIKKVW------SDIISVVIKTVIALTPELKVFYQSDIPTGRPG 508 + + K + K W + ++ +A P+L D G Sbjct: 440 MEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLAAKPKL------DCKLG--- 490 Query: 509 PTCFQILGFDILLMKNLKPILLEVNANPSMRIEHE--HELSPGVFENVPSLVDE 560 F ++G D L+ N K LLE+N+NP++ E E+ PGV LV E Sbjct: 491 --YFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLVLE 542 >gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo sapiens] Length = 834 Score = 61.6 bits (148), Expect = 3e-09 Identities = 56/205 (27%), Positives = 98/205 (47%), Gaps = 28/205 (13%) Query: 370 VVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRI- 428 VVQ+YI PLLI KFDIR + L+ +PL I+ K+ RF T+ + +L ++ Sbjct: 374 VVQKYIETPLLICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRF------SLDKLD 427 Query: 429 -FMHLTNYSLNIHSGNFIHSD----SASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483 +HL N ++ + N + + + + F L R +G VW +I Sbjct: 428 SAIHLCNNAVQKYLKNDVGRSPLLPAHNMWTSTRFQEYLQR-QGRGA----VWGSVIYPS 482 Query: 484 IKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHE 543 +K IA ++ Q + P F++ G D +L ++ +P L+E+N++P+M Sbjct: 483 MKKAIAHAMKVA---QDHV---EPRKNSFELYGADFVLGRDFRPWLIEINSSPTM----- 531 Query: 544 HELSPGVFENVPSLVDEEVKVAVIR 568 H +P + + ++ +KVAV R Sbjct: 532 HPSTPVTAQLCAQVQEDTIKVAVDR 556 >gi|73476377 LBXCOR1 homolog [Homo sapiens] Length = 921 Score = 51.6 bits (122), Expect = 3e-06 Identities = 60/182 (32%), Positives = 73/182 (40%), Gaps = 32/182 (17%) Query: 32 PRLDAVTAAVNPSLSDHGNGLGRGT-------------RGSGCSGGSLVADWG----GGA 74 P L A P G G G G G+G GG++ WG G A Sbjct: 368 PVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMF--WGHQPSGAA 425 Query: 75 AAAAAVALALAPA-------LSTMRRGSSE--SELAARWEAEAVAAAKAAAKAEAEATAE 125 AAAVA A A A + GS S AA+ +A+AVAAA AAA A A A A Sbjct: 426 KDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAG 485 Query: 126 TVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185 + A + A A E A E P L+ P E+G + L P LPP P P Sbjct: 486 SGAPEPLDGAEPAKESGLGAEERCPSALSRGPLD----EDGTDEALPPPLAPLPPPPPPP 541 Query: 186 VQ 187 + Sbjct: 542 AR 543 >gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens] Length = 496 Score = 47.4 bits (111), Expect = 5e-05 Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 15/176 (8%) Query: 30 PGPRLDAVTAA------VNPSLSDHGNGLGRGTRGSGCSGGSLVADWG-GGAAAAAAVAL 82 PGP L A++A V P G+G G G G G + WG AAAAAA +L Sbjct: 140 PGPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAG--LGSWGLAEAAAAAAASL 197 Query: 83 ALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRV--DAGAAGE 140 + RR ELAA W A + E + A + E+ ++ D G Sbjct: 198 PPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFNAPALLERHKLTHDLQGPGA 257 Query: 141 PECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPS---KPKPVQGLCPHG 193 P +A P + +AAE G+ + L P+ PK + GL P G Sbjct: 258 PPAQAWAAGPGAGPETAGEGTAAEAGDAPLASDRRLLLGPAGGGVPK-LGGLLPEG 312 >gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform 2 [Homo sapiens] Length = 404 Score = 46.6 bits (109), Expect = 9e-05 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 34/160 (21%) Query: 291 VRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIY 350 V M+ FPE Y L E + F + D+ W I KP QG GI+ Sbjct: 205 VLRMEEFFPETYRLD-----LKHEREAFFT----LFDETQIW----ICKPTASNQGKGIF 251 Query: 351 LIKDPSDIRL----AGTLQSRPA------------VVQEYICKPLLIDKLKFDIRLYVLL 394 L+++ ++ +++ P VVQ YI PLL+D KFD+R Y+L+ Sbjct: 252 LLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLI 311 Query: 395 KSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTN 434 P I+ G +R Y +P +L HLTN Sbjct: 312 ACTTPYMIFFG-HGYARLTLSLY-DPHSSDLGG---HLTN 346 >gi|4506975 solute carrier family 12 (sodium/potassium/chloride transporters), member 2 [Homo sapiens] Length = 1212 Score = 44.3 bits (103), Expect = 5e-04 Identities = 49/168 (29%), Positives = 66/168 (39%), Gaps = 24/168 (14%) Query: 2 AAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGC 61 A ++ G +P + R+ LPG + +V P+ D G G R G Sbjct: 7 APSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGG-----GVRDEG- 60 Query: 62 SGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAE 121 AAA + L P S R + +L + A AAA AAA A A Sbjct: 61 -----------PAAAGDGLGRPLGPTPSQSR---FQVDLVSENAGRAAAAAAAAAAAAAA 106 Query: 122 ATAETVAEQVRVDAGAAGEPECKAGEEQPK----VLAPAPAQPSAAEE 165 A A A+Q D A+GE E G E+ K V PA S+AE+ Sbjct: 107 AGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAED 154 >gi|45439359 triple functional domain (PTPRF interacting) [Homo sapiens] Length = 3097 Score = 43.9 bits (102), Expect = 6e-04 Identities = 51/187 (27%), Positives = 73/187 (39%), Gaps = 37/187 (19%) Query: 34 LDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAP-----AL 88 L+A+T+ + + G G G G+ GSG GGS GGG A + + P A Sbjct: 2277 LNALTSPIEYQRNHSGGGGGGGSGGSGGGGGS-----GGGGAPSGGSGHSGGPSSCGGAP 2331 Query: 89 STMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEE 148 ST R S R + ++ A+++AEA+ + T G + P A E Sbjct: 2332 STSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGTST------PGPSLPPPGAAPEA 2385 Query: 149 QPKVLAPAPAQPSAAEEGN---------TQVLQRP----------PPTLPPSKPKPVQGL 189 P AP+ P A EG+ +VL+ P P P + G Sbjct: 2386 GPS--APSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGT 2443 Query: 190 CPHGKPR 196 P GKPR Sbjct: 2444 LPLGKPR 2450 >gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo sapiens] Length = 644 Score = 43.9 bits (102), Expect = 6e-04 Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 15/140 (10%) Query: 272 VNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVK--DDD 329 +N+FP + K L+ R PE + PR++ L E FV+ Q + +D Sbjct: 356 LNQFPCENLLTVKDCLASIARRAGG--PEGPPWLPRTFNLRTELPQFVSYFQQRERWGED 413 Query: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLL-----IDKL 384 W I KP + ++ K I +S P VV +YI P+L + K+ Sbjct: 414 NHW----ICKPWNLARSLDTHVTKSLHSI--IRHRESTPKVVSKYIESPVLFLREDVGKV 467 Query: 385 KFDIRLYVLLKSLDPLEIYI 404 KFDIR VLL+S+ PL +++ Sbjct: 468 KFDIRYIVLLRSVRPLRLFV 487 >gi|5453936 POU class 3 homeobox 3 [Homo sapiens] Length = 500 Score = 43.1 bits (100), Expect = 0.001 Identities = 53/183 (28%), Positives = 65/183 (35%), Gaps = 33/183 (18%) Query: 29 LPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPAL 88 LPG L A + V+ + G G G G G G G G+AA + A P+ Sbjct: 10 LPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSS 69 Query: 89 STM------------RRGSSESELAARWEA---EAVAAAKAAAKAEAEATAETVAEQVRV 133 M G A +W A AAA AAA A EA++ V Sbjct: 70 VKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAV-- 127 Query: 134 DAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEG--------NTQVLQRPPPTLPPSKPKP 185 G AG P +QP P P Q + G T + R PP L P P P Sbjct: 128 --GMAGSP------QQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPP 179 Query: 186 VQG 188 QG Sbjct: 180 HQG 182 >gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] Length = 651 Score = 41.2 bits (95), Expect = 0.004 Identities = 49/154 (31%), Positives = 56/154 (36%), Gaps = 17/154 (11%) Query: 47 DHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARW-- 104 D G G G G G G +G D G G A A APA R E + AA Sbjct: 9 DGGGGGGGGGGGVGAAG----EDPGPGPAPPPEGAQEAAPA----PRPPPEPDDAAAALR 60 Query: 105 ----EAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEEQ--PKVLAPAPA 158 + A+ A E A + A D GAA EP G E P LAPA A Sbjct: 61 LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120 Query: 159 QPSAAEEGNTQVLQRPPPTLPPSKPKPVQGLCPH 192 P + + PPP PS P G PH Sbjct: 121 -PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPH 153 >gi|19111150 angiomotin isoform 2 [Homo sapiens] Length = 675 Score = 40.8 bits (94), Expect = 0.005 Identities = 39/119 (32%), Positives = 48/119 (40%), Gaps = 11/119 (9%) Query: 74 AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRV 133 AA AAA+ A +TM +AA A A AAA AAA A + ATA A V Sbjct: 481 AATAAAITATAATITTTM--------VAAAPVAVAAAAAPAAAAAPSPATAAATA--AAV 530 Query: 134 DAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTL-PPSKPKPVQGLCP 191 AAG+ A +AP+ A +A + P P L P P Q P Sbjct: 531 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAP 589 Score = 39.3 bits (90), Expect = 0.015 Identities = 39/113 (34%), Positives = 45/113 (39%), Gaps = 4/113 (3%) Query: 74 AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAK-AEAEATAETVAEQVR 132 AAA AVA A APA + ++ + AA A AAA A A A A + A Sbjct: 500 AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAA 559 Query: 133 VDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185 V A A P V APA AQ SA + TQ P P P P Sbjct: 560 VQVAPAAPAPVPAPALVP-VPAPAAAQASAPAQ--TQAPTSAPAVAPTPAPTP 609 Score = 34.7 bits (78), Expect = 0.36 Identities = 37/111 (33%), Positives = 45/111 (40%), Gaps = 5/111 (4%) Query: 75 AAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVD 134 AAA A A++ A A S S A A A AA + A A A A + V V Sbjct: 523 AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL---VPVP 579 Query: 135 AGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185 A AA + A + P APA A P+ A V Q P P + P P Sbjct: 580 APAAAQASAPAQTQAP-TSAPAVA-PTPAPTPTPAVAQAEVPASPATGPGP 628 >gi|166064029 angiomotin isoform 1 [Homo sapiens] Length = 1084 Score = 40.8 bits (94), Expect = 0.005 Identities = 39/119 (32%), Positives = 48/119 (40%), Gaps = 11/119 (9%) Query: 74 AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRV 133 AA AAA+ A +TM +AA A A AAA AAA A + ATA A V Sbjct: 890 AATAAAITATAATITTTM--------VAAAPVAVAAAAAPAAAAAPSPATAAATA--AAV 939 Query: 134 DAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTL-PPSKPKPVQGLCP 191 AAG+ A +AP+ A +A + P P L P P Q P Sbjct: 940 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAP 998 Score = 39.3 bits (90), Expect = 0.015 Identities = 39/113 (34%), Positives = 45/113 (39%), Gaps = 4/113 (3%) Query: 74 AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAK-AEAEATAETVAEQVR 132 AAA AVA A APA + ++ + AA A AAA A A A A + A Sbjct: 909 AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAA 968 Query: 133 VDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185 V A A P V APA AQ SA + TQ P P P P Sbjct: 969 VQVAPAAPAPVPAPALVP-VPAPAAAQASAPAQ--TQAPTSAPAVAPTPAPTP 1018 Score = 34.7 bits (78), Expect = 0.36 Identities = 37/111 (33%), Positives = 45/111 (40%), Gaps = 5/111 (4%) Query: 75 AAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVD 134 AAA A A++ A A S S A A A AA + A A A A + V V Sbjct: 932 AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL---VPVP 988 Query: 135 AGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185 A AA + A + P APA A P+ A V Q P P + P P Sbjct: 989 APAAAQASAPAQTQAP-TSAPAVA-PTPAPTPTPAVAQAEVPASPATGPGP 1037 >gi|239755810 PREDICTED: hypothetical protein [Homo sapiens] Length = 499 Score = 40.0 bits (92), Expect = 0.009 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 41/223 (18%) Query: 17 PMRS---LGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADW--- 70 P+RS LG G R PR A+ A PS + G GRGT G+G L+ + Sbjct: 262 PLRSGPPLGAGSR-----PR--ALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLITYRVL 313 Query: 71 --------GGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEA 122 GG A+ +++ +R G + + W+ A + Sbjct: 314 SNLRRTLCSGGGVASMRISVGRG-----LRAGPRAPDAGSFWDPNPQTLAPHPQASRRPR 368 Query: 123 TAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLP--- 179 +++ Q G AG P + AP+P + + +V +RP P P Sbjct: 369 AGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 428 Query: 180 ---PSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPV 219 S P+P+ L P R+ +SSGH S RP+ Sbjct: 429 NPATSSPRPLGPLRP--------RAGGQSSGHPDRTVTSPRPI 463 >gi|239750310 PREDICTED: hypothetical protein [Homo sapiens] Length = 499 Score = 40.0 bits (92), Expect = 0.009 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 41/223 (18%) Query: 17 PMRS---LGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADW--- 70 P+RS LG G R PR A+ A PS + G GRGT G+G L+ + Sbjct: 262 PLRSGPPLGAGSR-----PR--ALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLITYRVL 313 Query: 71 --------GGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEA 122 GG A+ +++ +R G + + W+ A + Sbjct: 314 SNLRRTLCSGGGVASMRISVGRG-----LRAGPRAPDAGSFWDPNPQTLAPHPQASRRPR 368 Query: 123 TAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLP--- 179 +++ Q G AG P + AP+P + + +V +RP P P Sbjct: 369 AGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 428 Query: 180 ---PSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPV 219 S P+P+ L P R+ +SSGH S RP+ Sbjct: 429 NPATSSPRPLGPLRP--------RAGGQSSGHPDRTVTSPRPI 463 >gi|239744621 PREDICTED: hypothetical protein [Homo sapiens] Length = 536 Score = 40.0 bits (92), Expect = 0.009 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 41/223 (18%) Query: 17 PMRS---LGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADW--- 70 P+RS LG G R PR A+ A PS + G GRGT G+G L+ + Sbjct: 299 PLRSGPPLGAGSR-----PR--ALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLITYRVL 350 Query: 71 --------GGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEA 122 GG A+ +++ +R G + + W+ A + Sbjct: 351 SNLRRTLCSGGGVASMRISVGRG-----LRAGPRAPDAGSFWDPNPQTLAPHPQASRRPR 405 Query: 123 TAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLP--- 179 +++ Q G AG P + AP+P + + +V +RP P P Sbjct: 406 AGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 465 Query: 180 ---PSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPV 219 S P+P+ L P R+ +SSGH S RP+ Sbjct: 466 NPATSSPRPLGPLRP--------RAGGQSSGHPDRTVTSPRPI 500 >gi|24497554 homeobox A13 [Homo sapiens] Length = 388 Score = 39.7 bits (91), Expect = 0.011 Identities = 39/107 (36%), Positives = 45/107 (42%), Gaps = 6/107 (5%) Query: 62 SGGSLVAD-----WGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAA 116 +GG LVAD G AAAAAA A A A A + + AA AAA AAA Sbjct: 22 NGGGLVADELNKNMEGAAAAAAAAA-AAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAA 80 Query: 117 KAEAEATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAA 163 A A +A + GAA GE P A A A +AA Sbjct: 81 AAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAA 127 Score = 35.4 bits (80), Expect = 0.21 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 6/131 (4%) Query: 28 SLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPA 87 ++ G A AA + G G + S+ A AAAAA L Sbjct: 34 NMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAH 93 Query: 88 LSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGE 147 + + G++ + +A EA AAA AAA A A A A + +G G P AG Sbjct: 94 PAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAAS-----SSGGPG-PAGPAGA 147 Query: 148 EQPKVLAPAPA 158 E K +P A Sbjct: 148 EAAKQCSPCSA 158 Score = 31.2 bits (69), Expect = 4.0 Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 8/90 (8%) Query: 94 GSSESELAARWEAEAVAAAKAAAKAEAEA--------TAETVAEQVRVDAGAAGEPECKA 145 G EL E A AAA AAA A A A A V A AA A Sbjct: 25 GLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAA 84 Query: 146 GEEQPKVLAPAPAQPSAAEEGNTQVLQRPP 175 + + + PAP P AA ++ + PP Sbjct: 85 NQCRNLMAHPAPLAPGAASAYSSAPGEAPP 114 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,625,944 Number of Sequences: 37866 Number of extensions: 1874043 Number of successful extensions: 16314 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 93 Number of HSP's successfully gapped in prelim test: 396 Number of HSP's that attempted gapping in prelim test: 13792 Number of HSP's gapped (non-prelim): 2612 length of query: 800 length of database: 18,247,518 effective HSP length: 110 effective length of query: 690 effective length of database: 14,082,258 effective search space: 9716758020 effective search space used: 9716758020 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.