Guide to the Human Genome
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Search of human proteins with 212720861

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212720861 tubulin tyrosine ligase-like family, member 11 a
[Homo sapiens]
         (800 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...  1614   0.0  
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...  1037   0.0  
gi|239755159 PREDICTED: similar to tubulin tyrosine ligase-like ...   447   e-125
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...   225   1e-58
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...   218   2e-56
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...   205   1e-52
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...   164   3e-40
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...   161   2e-39
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...   138   2e-32
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...   123   8e-28
gi|24308516 tubulin tyrosine ligase [Homo sapiens]                     81   4e-15
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...    79   2e-14
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    72   2e-12
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...    71   5e-12
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    62   2e-09
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...    62   3e-09
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             52   3e-06
gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]             47   5e-05
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    47   9e-05
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t...    44   5e-04
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    44   6e-04
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo...    44   6e-04
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       43   0.001
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]     41   0.004
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        41   0.005
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       41   0.005
gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]            40   0.009
gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]            40   0.009
gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]            40   0.009
gi|24497554 homeobox A13 [Homo sapiens]                                40   0.011

>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score = 1614 bits (4179), Expect = 0.0
 Identities = 800/800 (100%), Positives = 800/800 (100%)

Query: 1   MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60
           MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG
Sbjct: 1   MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60

Query: 61  CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120
           CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA
Sbjct: 61  CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120

Query: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180
           EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP
Sbjct: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180

Query: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240
           SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL
Sbjct: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240

Query: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300
           KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE
Sbjct: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300

Query: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360
           EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL
Sbjct: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360

Query: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420
           AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP
Sbjct: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420

Query: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480
           TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII
Sbjct: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480

Query: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRI 540
           SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRI
Sbjct: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRI 540

Query: 541 EHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALD 600
           EHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALD
Sbjct: 541 EHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALD 600

Query: 601 GELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGP 660
           GELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGP
Sbjct: 601 GELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGP 660

Query: 661 TGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQR 720
           TGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQR
Sbjct: 661 TGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQR 720

Query: 721 KFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGD 780
           KFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGD
Sbjct: 721 KFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGD 780

Query: 781 NPPPRTSCANKLSHPRHTLS 800
           NPPPRTSCANKLSHPRHTLS
Sbjct: 781 NPPPRTSCANKLSHPRHTLS 800


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score = 1037 bits (2681), Expect = 0.0
 Identities = 513/514 (99%), Positives = 514/514 (100%)

Query: 1   MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60
           MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG
Sbjct: 1   MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSG 60

Query: 61  CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120
           CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA
Sbjct: 61  CSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEA 120

Query: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180
           EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP
Sbjct: 121 EATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPP 180

Query: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240
           SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL
Sbjct: 181 SKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQL 240

Query: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300
           KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE
Sbjct: 241 KWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPE 300

Query: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360
           EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL
Sbjct: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360

Query: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420
           AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP
Sbjct: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420

Query: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480
           TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII
Sbjct: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480

Query: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQI 514
           SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQ+
Sbjct: 481 SVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQV 514


>gi|239755159 PREDICTED: similar to tubulin tyrosine ligase-like
           family, member 11 a [Homo sapiens]
          Length = 259

 Score =  447 bits (1149), Expect = e-125
 Identities = 216/219 (98%), Positives = 219/219 (100%)

Query: 582 ENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDR 641
           +++SQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDR
Sbjct: 41  QSRSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDR 100

Query: 642 MANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQR 701
           MANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQR
Sbjct: 101 MANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQR 160

Query: 702 DSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGR 761
           DSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGR
Sbjct: 161 DSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGR 220

Query: 762 PPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS 800
           PPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS
Sbjct: 221 PPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS 259


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score =  225 bits (574), Expect = 1e-58
 Identities = 130/329 (39%), Positives = 190/329 (57%), Gaps = 34/329 (10%)

Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDP 330
           ++N FPGMTE+ RK  L+R +  M  L+P EYN +PR+W LP ++  F +  +  K    
Sbjct: 140 KINHFPGMTEICRKDLLARNLNRMYKLYPSEYNIFPRTWCLPADYGDFQSYGRQRK---- 195

Query: 331 SWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRL 390
               T+I KPD GCQG GI++ ++P +I+          + Q+YI KPLLID  KFD+R+
Sbjct: 196 --ARTYICKPDSGCQGRGIFITRNPREIK-----PGEHMICQQYISKPLLIDGFKFDMRV 248

Query: 391 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSA 450
           YVL+ S DPL I+  ++GL+RF T PY EP+  NL  + MHLTNY++N H+ NF+     
Sbjct: 249 YVLITSCDPLRIFTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVR--DG 306

Query: 451 STGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPT 510
           + GSKR  S++   L     +  ++W DI  ++IKT+I+    L+  Y++  P    G T
Sbjct: 307 AVGSKRKLSTLNIWLQEHSYNPGELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGT 366

Query: 511 --CFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIR 568
             CF+ILGFDILL   LKP LLEVN +PS   +              S +D+EVK A++ 
Sbjct: 367 CACFEILGFDILLDHKLKPWLLEVNHSPSFTTD--------------SCLDQEVKDALLC 412

Query: 569 DTLRLM-----DPLKKKRENQSQQLEKPF 592
           D + L+     D  K   E++ +  E+ F
Sbjct: 413 DAMTLVNLRGCDKRKVMEEDKRRVKERLF 441


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score =  218 bits (554), Expect = 2e-56
 Identities = 121/305 (39%), Positives = 175/305 (57%), Gaps = 27/305 (8%)

Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDP 330
           ++N FPGM+E+ RK  L+R +  M  +FP+++ F+PR+W LP ++       +  K+   
Sbjct: 161 KINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPADWGDLQTYSRSRKNK-- 218

Query: 331 SWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRL 390
               T+I KPD GCQG GI++ +   +I+          + Q YI KP +ID  KFD+R+
Sbjct: 219 ----TYICKPDSGCQGKGIFITRTVKEIK-----PGEDMICQLYISKPFIIDGFKFDLRI 269

Query: 391 YVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSA 450
           YVL+ S DPL I++  +GL+RF T  Y  P   NL  I MHLTNYS+N HS NF  S  A
Sbjct: 270 YVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNF--SRDA 327

Query: 451 STGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPT 510
            +GSKR  S+    L     +++++W DI  V+IKT+I+  P ++  Y +  P       
Sbjct: 328 HSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSA 387

Query: 511 CFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDT 570
           CF+ILGFDILL   LKP LLEVN +PS               +  S +D+EVK  ++ DT
Sbjct: 388 CFEILGFDILLDHKLKPWLLEVNHSPSF--------------STDSRLDKEVKDGLLYDT 433

Query: 571 LRLMD 575
           L L++
Sbjct: 434 LVLIN 438


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score =  205 bits (522), Expect = 1e-52
 Identities = 136/410 (33%), Positives = 209/410 (50%), Gaps = 29/410 (7%)

Query: 185 PVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKE 244
           P +G+     P D        S         ++  T+ ++ A T  + +++ I ++ + +
Sbjct: 5   PQEGVIQGPSPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMK 64

Query: 245 FPFGRRLPCDIYWHGVSFHDNDIFSGQ----VNKFPGMTEMVRKITLSRAVRTMQNLFPE 300
            P       ++ W   +     I   Q    +N FPGM E+ RK  L+R +  M    P 
Sbjct: 65  TP-DEDETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPL 123

Query: 301 EYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRL 360
           +Y F PR+WI P E+  F   V+ +K      + TFIVKP  G  G GI LI++   +  
Sbjct: 124 DYTFVPRTWIFPAEYTQFQNYVKELKKKRK--QKTFIVKPANGAMGHGISLIRNGDKLPS 181

Query: 361 AGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEP 420
              L     +VQEYI KP L++  KFD+R+Y+L+ S DPL+I++  DGL R  TE Y  P
Sbjct: 182 QDHL-----IVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPP 236

Query: 421 TPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDII 480
              NL +++MHLTNYS+N H+ +F   ++ + GSKR+       L +   D+ K WSDI 
Sbjct: 237 NESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDIS 296

Query: 481 SVVIKTVIALTPELKVFYQSDIPTGRPG--PTCFQILGFDILLMKNLKPILLEVNANPSM 538
            +V+KT+I   P +   Y+   P   PG    CF++LGFDILL + LKP LLE+N  PS 
Sbjct: 297 ELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSF 356

Query: 539 RIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMD-PLKKKRENQSQQ 587
             + +              +D +VK  V+ + L+L++     KR N ++Q
Sbjct: 357 GTDQK--------------IDYDVKRGVLLNALKLLNIRTSDKRRNLAKQ 392


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
           sapiens]
          Length = 1199

 Score =  164 bits (415), Expect = 3e-40
 Identities = 112/306 (36%), Positives = 169/306 (55%), Gaps = 32/306 (10%)

Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLF-PEEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329
           ++N FPG  ++ RK  L R +  MQ+ F  +E++F+P+S+ILP + +L      + K  +
Sbjct: 658 KLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKL------LRKAWE 711

Query: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389
            S +  +IVKP    +G GI +I   S +      + RP +VQ Y+ KP LI   KFD+R
Sbjct: 712 SSSRQKWIVKPPASARGIGIQVIHKWSQLP-----KRRPLLVQRYLHKPYLISGSKFDLR 766

Query: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHS-- 447
           +YV + S DPL IY+  DGL RF +  Y  P+ K+L   FMHLTNYS+N  +  +  +  
Sbjct: 767 IYVYVTSYDPLRIYLFSDGLVRFASCKY-SPSMKSLGNKFMHLTNYSVNKKNAEYQANAD 825

Query: 448 DSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRP 507
           + A  G K    ++   LS KGV+   +W  I  VV+KT+I+  P +    +  +   R 
Sbjct: 826 EMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYV---RR 882

Query: 508 GPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVI 567
             +C ++ GFDI+L +NLKP +LEVN +PS+     H  SP         +D  +K  +I
Sbjct: 883 PYSCHELFGFDIMLDENLKPWVLEVNISPSL-----HSSSP---------LDISIKGQMI 928

Query: 568 RDTLRL 573
           RD L L
Sbjct: 929 RDLLNL 934


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
           sapiens]
          Length = 1281

 Score =  161 bits (408), Expect = 2e-39
 Identities = 100/272 (36%), Positives = 155/272 (56%), Gaps = 20/272 (7%)

Query: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLFP-EEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329
           +VN FP   E+ RK  L + +  MQ+    + ++  P++++LP E+  F       KD  
Sbjct: 118 KVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYS--KDRG 175

Query: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389
           P     +IVKP    +G G+YLI +P+ I L   +     +V  YI  PLLID  KFD+R
Sbjct: 176 P-----WIVKPVASSRGRGVYLINNPNQISLEENI-----LVSRYINNPLLIDDFKFDVR 225

Query: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDS 449
           LYVL+ S DPL IY+ ++GL+RF T  Y +   KN+   FMHLTNYS+N  SG+++  D 
Sbjct: 226 LYVLVTSYDPLVIYLYEEGLARFATVRYDQGA-KNIRNQFMHLTNYSVNKKSGDYVSCDD 284

Query: 450 AST---GSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGR 506
                 G+K + S++L  L  +G D   + + +  ++IKT+I+    +    ++ +P   
Sbjct: 285 PEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVP--- 341

Query: 507 PGPTCFQILGFDILLMKNLKPILLEVNANPSM 538
              +CF++ GFD+L+   LKP LLEVN +PS+
Sbjct: 342 HRSSCFELYGFDVLIDSTLKPWLLEVNLSPSL 373


>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score =  138 bits (348), Expect = 2e-32
 Identities = 95/298 (31%), Positives = 149/298 (50%), Gaps = 33/298 (11%)

Query: 254 DIYWHGVSFHDNDIFS----GQVNKFPGMTEMVRKITLSRAVRTMQNLFPEE-YNFYPRS 308
           ++YW   SF   +  S     Q+N  PG T++ RK  L++ ++ M+ ++    Y F P +
Sbjct: 122 NLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLT 181

Query: 309 WILPDEFQLFVAQV----QMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTL 364
           +++P+++  FVA+     QM+      W    I KP    +G GI +  D  D      +
Sbjct: 182 FVMPNDYTKFVAEYFQERQMLGTKHSYW----ICKPAELSRGRGILIFSDFKDF-----I 232

Query: 365 QSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKN 424
                +VQ+YI  PLLI + K D+R+YV +    PL IY+ ++GL RF TE +      N
Sbjct: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSN 289

Query: 425 LHRIFMHLTNYSLNIHSGNFIH-SDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483
           L   + HLTN S+N    ++    +    G K T S     L S  VD   +W  I  +V
Sbjct: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349

Query: 484 IKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIE 541
           I T++A+ P +                CF++ GFDIL+  NLKP LLEVN +P++ ++
Sbjct: 350 ILTILAIAPSVPF-----------AANCFELFGFDILIDDNLKPWLLEVNYSPALTLD 396


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score =  123 bits (308), Expect = 8e-28
 Identities = 96/332 (28%), Positives = 155/332 (46%), Gaps = 63/332 (18%)

Query: 272 VNKFPGMTEMVRKITLSRAVRTMQNLFPEE---------------YNFYPRSWILPDEFQ 316
           VN FP   E+ RK  + + ++  +    +E                +F P +++LP ++ 
Sbjct: 62  VNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYN 121

Query: 317 LFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIR----------LAGTLQS 366
           LFV + +       S   T+I+KP G  QG GI+LI   S I+                 
Sbjct: 122 LFVEEFRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK 175

Query: 367 RPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426
              V+  YI  PLLI   KFD+RLYVL+ +  PL  Y+ K G  RFCT  Y  P+   L 
Sbjct: 176 EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKY-TPSTSELD 234

Query: 427 RIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRL-SSKGVDI-KKVWSDIISVVI 484
            +F+HLTN ++  H  ++ H      G K T S++   L S++G ++  K++ +I  +++
Sbjct: 235 NMFVHLTNVAIQKHGEDYNHIH----GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIV 290

Query: 485 KTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEH 544
           +++ A+ P +                CF+  G+DI++   LKP L+EVNA+PS+     +
Sbjct: 291 QSLKAVAPVM-----------NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTAN 339

Query: 545 ELSPGVFENVPSLVDEEVKVAVIRDTLRLMDP 576
                         D  +K  +I DTL +  P
Sbjct: 340 --------------DRILKYNLINDTLNIAVP 357


>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 78/310 (25%), Positives = 137/310 (44%), Gaps = 48/310 (15%)

Query: 272 VNKFPGMTEMVRKITLSRAVRTMQNL------FPEEYNFYPRSWILP------------- 312
           VN + G  ++ RK +L + ++T   L      FPE Y  YP +   P             
Sbjct: 62  VNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPIS 121

Query: 313 ----DEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRP 368
               DE + F+A     K+D       +I K   G +G+GI +  + S++      Q + 
Sbjct: 122 NSRTDEREFFLASYNRKKEDGEG--NVWIAKSSAGAKGEGILISSEASELLDFIDNQGQV 179

Query: 369 AVVQEYICKPLLIDK--LKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426
            V+Q+Y+  PLL++    KFDIR +VL+       IY+ ++G+ R  +EPY      N  
Sbjct: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVDH--QYNIYLYREGVLRTASEPYHVD---NFQ 234

Query: 427 RIFMHLTNYSLNI-HSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIK 485
               HLTN+ +   +S N+   +  +    + F+  L    +  ++   +   I  ++  
Sbjct: 235 DKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLE-SSILLQIKHIIRN 293

Query: 486 TVIALTPELKVF---YQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEH 542
            ++++ P +      YQS           FQ+ GFD ++ + LK  L+EVN  P+   + 
Sbjct: 294 CLLSVEPAISTKHLPYQS-----------FQLFGFDFMVDEELKVWLIEVNGAPACAQKL 342

Query: 543 EHELSPGVFE 552
             EL  G+ +
Sbjct: 343 YAELCQGIVD 352


>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 87/337 (25%), Positives = 153/337 (45%), Gaps = 65/337 (19%)

Query: 253 CDIYWHGVSF-HDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEY--------N 303
           CD+ W   +F H       +++ F    E+ RK  + + ++  +     E         +
Sbjct: 78  CDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCD 137

Query: 304 FYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDI----- 358
           F+P+++ +P E+ LFV + +  K+   +W    I+KP    QG GI+L +   DI     
Sbjct: 138 FFPKTFEMPCEYHLFVEEFR--KNPGITW----IMKPVARSQGKGIFLFRRLKDIVDWRK 191

Query: 359 ------RLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRF 412
                      +     V Q YI  P LI   KFD+R+YVL+ S+               
Sbjct: 192 DTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSV--------------- 236

Query: 413 CTEPYQEPTPKNLHRIF-MHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSK-GV 470
               + E    + HR   +HLTN ++   S ++        G K T       L+SK G 
Sbjct: 237 ----FAECLLWSGHRRQDVHLTNVAVQKTSPDY----HPKKGCKWTLQRFRQYLASKHGP 288

Query: 471 D-IKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPIL 529
           + ++ ++ DI ++ +K++ ++    KV              CF++ G+DIL+ ++LKP L
Sbjct: 289 EAVETLFRDIDNIFVKSLQSVQ---KVIISDK--------HCFELYGYDILIDQDLKPWL 337

Query: 530 LEVNANPSMRI--EHEHELSPGVFENVPSLVDEEVKV 564
           LEVNA+PS+    + ++EL   + E+   +VD E ++
Sbjct: 338 LEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARL 374


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 43/120 (35%), Positives = 64/120 (53%), Gaps = 14/120 (11%)

Query: 456 RTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQIL 515
           R  S+    L     +++++W DI  V+IKT+I+  P ++  Y +  P       CF+IL
Sbjct: 26  RKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEIL 85

Query: 516 GFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMD 575
           GFDILL   LKP LLEVN +PS               +  S +D+EVK  ++ DTL L++
Sbjct: 86  GFDILLDHKLKPWLLEVNHSPSF--------------STDSRLDKEVKDGLLYDTLVLIN 131


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 63/230 (27%), Positives = 106/230 (46%), Gaps = 21/230 (9%)

Query: 314 EFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSD-IRLAG----TLQSRP 368
           + Q  V Q+ M  D     +  +IVKP    +G GI  +    + ++L       ++   
Sbjct: 263 QLQAVVPQIDMEGD-----RNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGK 317

Query: 369 AVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRI 428
            VVQ+YI +PLLI   KFD+R + L+   +PL ++  +D   RF T+P+   + KNL   
Sbjct: 318 WVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF---SLKNLDN- 373

Query: 429 FMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVI 488
            +HL N S+  H  N  H           +SS   +   + +     WS II   +K  +
Sbjct: 374 SVHLCNNSIQKHLENSCHRHPL-LPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAV 432

Query: 489 ALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSM 538
                     Q+   T +     F++ G D +  ++ +P L+E+NA+P+M
Sbjct: 433 IHA------LQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTM 476


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 76/294 (25%), Positives = 117/294 (39%), Gaps = 53/294 (18%)

Query: 291 VRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIY 350
           V  M+  FPE Y        L  E + F      + D+   W    I KP    QG GI+
Sbjct: 278 VLRMEEFFPETYRLD-----LKHEREAFFT----LFDETQIW----ICKPTASNQGKGIF 324

Query: 351 LIKDPSDIRL----AGTLQSRPA------------VVQEYICKPLLIDKLKFDIRLYVLL 394
           L+++  ++        +++  P             VVQ YI  PLL+D  KFD+R Y+L+
Sbjct: 325 LLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLI 384

Query: 395 KSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGS 454
               P  I+    G +R     Y +P   +L     HLTN  +   S  ++     +  S
Sbjct: 385 ACTTPYMIFFG-HGYARLTLSLY-DPHSSDLGG---HLTNQFMQKKSPLYMLLKEHTVWS 439

Query: 455 KRTFSSILCRLSSKGVDIKKVW------SDIISVVIKTVIALTPELKVFYQSDIPTGRPG 508
               +  +     K   + K W        +  ++    +A  P+L      D   G   
Sbjct: 440 MEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLAAKPKL------DCKLG--- 490

Query: 509 PTCFQILGFDILLMKNLKPILLEVNANPSMRIEHE--HELSPGVFENVPSLVDE 560
              F ++G D L+  N K  LLE+N+NP++    E   E+ PGV      LV E
Sbjct: 491 --YFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLVLE 542


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 56/205 (27%), Positives = 98/205 (47%), Gaps = 28/205 (13%)

Query: 370 VVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRI- 428
           VVQ+YI  PLLI   KFDIR + L+   +PL I+  K+   RF T+ +      +L ++ 
Sbjct: 374 VVQKYIETPLLICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRF------SLDKLD 427

Query: 429 -FMHLTNYSLNIHSGNFIHSD----SASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483
             +HL N ++  +  N +       + +  +   F   L R   +G     VW  +I   
Sbjct: 428 SAIHLCNNAVQKYLKNDVGRSPLLPAHNMWTSTRFQEYLQR-QGRGA----VWGSVIYPS 482

Query: 484 IKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHE 543
           +K  IA   ++    Q  +    P    F++ G D +L ++ +P L+E+N++P+M     
Sbjct: 483 MKKAIAHAMKVA---QDHV---EPRKNSFELYGADFVLGRDFRPWLIEINSSPTM----- 531

Query: 544 HELSPGVFENVPSLVDEEVKVAVIR 568
           H  +P   +    + ++ +KVAV R
Sbjct: 532 HPSTPVTAQLCAQVQEDTIKVAVDR 556


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 60/182 (32%), Positives = 73/182 (40%), Gaps = 32/182 (17%)

Query: 32  PRLDAVTAAVNPSLSDHGNGLGRGT-------------RGSGCSGGSLVADWG----GGA 74
           P L A      P     G G G G               G+G  GG++   WG    G A
Sbjct: 368 PVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMF--WGHQPSGAA 425

Query: 75  AAAAAVALALAPA-------LSTMRRGSSE--SELAARWEAEAVAAAKAAAKAEAEATAE 125
             AAAVA A A A       +     GS    S  AA+ +A+AVAAA AAA A A A A 
Sbjct: 426 KDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAG 485

Query: 126 TVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185
           + A +    A  A E    A E  P  L+  P      E+G  + L  P   LPP  P P
Sbjct: 486 SGAPEPLDGAEPAKESGLGAEERCPSALSRGPLD----EDGTDEALPPPLAPLPPPPPPP 541

Query: 186 VQ 187
            +
Sbjct: 542 AR 543


>gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]
          Length = 496

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 15/176 (8%)

Query: 30  PGPRLDAVTAA------VNPSLSDHGNGLGRGTRGSGCSGGSLVADWG-GGAAAAAAVAL 82
           PGP L A++A       V P     G+G G G    G   G  +  WG   AAAAAA +L
Sbjct: 140 PGPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAG--LGSWGLAEAAAAAAASL 197

Query: 83  ALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRV--DAGAAGE 140
                 +  RR     ELAA W A          + E +  A  + E+ ++  D    G 
Sbjct: 198 PPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFNAPALLERHKLTHDLQGPGA 257

Query: 141 PECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPS---KPKPVQGLCPHG 193
           P  +A    P        + +AAE G+  +       L P+    PK + GL P G
Sbjct: 258 PPAQAWAAGPGAGPETAGEGTAAEAGDAPLASDRRLLLGPAGGGVPK-LGGLLPEG 312


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 34/160 (21%)

Query: 291 VRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIY 350
           V  M+  FPE Y        L  E + F      + D+   W    I KP    QG GI+
Sbjct: 205 VLRMEEFFPETYRLD-----LKHEREAFFT----LFDETQIW----ICKPTASNQGKGIF 251

Query: 351 LIKDPSDIRL----AGTLQSRPA------------VVQEYICKPLLIDKLKFDIRLYVLL 394
           L+++  ++        +++  P             VVQ YI  PLL+D  KFD+R Y+L+
Sbjct: 252 LLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLI 311

Query: 395 KSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTN 434
               P  I+    G +R     Y +P   +L     HLTN
Sbjct: 312 ACTTPYMIFFG-HGYARLTLSLY-DPHSSDLGG---HLTN 346


>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
           transporters), member 2 [Homo sapiens]
          Length = 1212

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 49/168 (29%), Positives = 66/168 (39%), Gaps = 24/168 (14%)

Query: 2   AAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGC 61
           A ++   G      +P  +     R+ LPG  + +V     P+  D G     G R  G 
Sbjct: 7   APSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGG-----GVRDEG- 60

Query: 62  SGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAE 121
                       AAA   +   L P  S  R    + +L +     A AAA AAA A A 
Sbjct: 61  -----------PAAAGDGLGRPLGPTPSQSR---FQVDLVSENAGRAAAAAAAAAAAAAA 106

Query: 122 ATAETVAEQVRVDAGAAGEPECKAGEEQPK----VLAPAPAQPSAAEE 165
           A A   A+Q   D  A+GE E   G E+ K    V    PA  S+AE+
Sbjct: 107 AGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAED 154


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 51/187 (27%), Positives = 73/187 (39%), Gaps = 37/187 (19%)

Query: 34   LDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAP-----AL 88
            L+A+T+ +    +  G G G G+ GSG  GGS     GGG A +     +  P     A 
Sbjct: 2277 LNALTSPIEYQRNHSGGGGGGGSGGSGGGGGS-----GGGGAPSGGSGHSGGPSSCGGAP 2331

Query: 89   STMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEE 148
            ST R   S      R     + ++ A+++AEA+  + T         G +  P   A E 
Sbjct: 2332 STSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGTST------PGPSLPPPGAAPEA 2385

Query: 149  QPKVLAPAPAQPSAAEEGN---------TQVLQRP----------PPTLPPSKPKPVQGL 189
             P   AP+   P A  EG+          +VL+ P           P  P    +   G 
Sbjct: 2386 GPS--APSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGT 2443

Query: 190  CPHGKPR 196
             P GKPR
Sbjct: 2444 LPLGKPR 2450


>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
           sapiens]
          Length = 644

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 15/140 (10%)

Query: 272 VNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVK--DDD 329
           +N+FP    +  K  L+   R      PE   + PR++ L  E   FV+  Q  +   +D
Sbjct: 356 LNQFPCENLLTVKDCLASIARRAGG--PEGPPWLPRTFNLRTELPQFVSYFQQRERWGED 413

Query: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLL-----IDKL 384
             W    I KP    +    ++ K    I      +S P VV +YI  P+L     + K+
Sbjct: 414 NHW----ICKPWNLARSLDTHVTKSLHSI--IRHRESTPKVVSKYIESPVLFLREDVGKV 467

Query: 385 KFDIRLYVLLKSLDPLEIYI 404
           KFDIR  VLL+S+ PL +++
Sbjct: 468 KFDIRYIVLLRSVRPLRLFV 487


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 53/183 (28%), Positives = 65/183 (35%), Gaps = 33/183 (18%)

Query: 29  LPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPAL 88
           LPG  L A  + V+   +  G G G G  G G   G        G+AA  + A    P+ 
Sbjct: 10  LPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSS 69

Query: 89  STM------------RRGSSESELAARWEA---EAVAAAKAAAKAEAEATAETVAEQVRV 133
             M              G      A +W      A AAA AAA A  EA++      V  
Sbjct: 70  VKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAV-- 127

Query: 134 DAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEG--------NTQVLQRPPPTLPPSKPKP 185
             G AG P      +QP    P P Q    + G         T +  R PP L P  P P
Sbjct: 128 --GMAGSP------QQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPP 179

Query: 186 VQG 188
            QG
Sbjct: 180 HQG 182


>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
          Length = 651

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 49/154 (31%), Positives = 56/154 (36%), Gaps = 17/154 (11%)

Query: 47  DHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARW-- 104
           D G G G G  G G +G     D G G A     A   APA     R   E + AA    
Sbjct: 9   DGGGGGGGGGGGVGAAG----EDPGPGPAPPPEGAQEAAPA----PRPPPEPDDAAAALR 60

Query: 105 ----EAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEEQ--PKVLAPAPA 158
               +  A+    A    E  A  +  A     D GAA EP    G E   P  LAPA A
Sbjct: 61  LALDQLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVA 120

Query: 159 QPSAAEEGNTQVLQRPPPTLPPSKPKPVQGLCPH 192
            P +    +      PPP   PS P    G  PH
Sbjct: 121 -PGSLPLLDPNASPPPPPPPRPSPPDVFAGFAPH 153


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 39/119 (32%), Positives = 48/119 (40%), Gaps = 11/119 (9%)

Query: 74  AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRV 133
           AA AAA+    A   +TM        +AA   A A AAA AAA A + ATA   A    V
Sbjct: 481 AATAAAITATAATITTTM--------VAAAPVAVAAAAAPAAAAAPSPATAAATA--AAV 530

Query: 134 DAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTL-PPSKPKPVQGLCP 191
              AAG+    A       +AP+ A  +A +         P P L P   P   Q   P
Sbjct: 531 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAP 589



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 39/113 (34%), Positives = 45/113 (39%), Gaps = 4/113 (3%)

Query: 74  AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAK-AEAEATAETVAEQVR 132
           AAA  AVA A APA +     ++ +  AA     A     AAA  A A A A + A    
Sbjct: 500 AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAA 559

Query: 133 VDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185
           V    A      A    P V APA AQ SA  +  TQ     P   P   P P
Sbjct: 560 VQVAPAAPAPVPAPALVP-VPAPAAAQASAPAQ--TQAPTSAPAVAPTPAPTP 609



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 37/111 (33%), Positives = 45/111 (40%), Gaps = 5/111 (4%)

Query: 75  AAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVD 134
           AAA A A++ A A       S  S  A    A A AA + A  A A   A  +   V V 
Sbjct: 523 AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL---VPVP 579

Query: 135 AGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185
           A AA +    A  + P   APA A P+ A      V Q   P  P + P P
Sbjct: 580 APAAAQASAPAQTQAP-TSAPAVA-PTPAPTPTPAVAQAEVPASPATGPGP 628


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 39/119 (32%), Positives = 48/119 (40%), Gaps = 11/119 (9%)

Query: 74  AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRV 133
           AA AAA+    A   +TM        +AA   A A AAA AAA A + ATA   A    V
Sbjct: 890 AATAAAITATAATITTTM--------VAAAPVAVAAAAAPAAAAAPSPATAAATA--AAV 939

Query: 134 DAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTL-PPSKPKPVQGLCP 191
              AAG+    A       +AP+ A  +A +         P P L P   P   Q   P
Sbjct: 940 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAP 998



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 39/113 (34%), Positives = 45/113 (39%), Gaps = 4/113 (3%)

Query: 74   AAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAK-AEAEATAETVAEQVR 132
            AAA  AVA A APA +     ++ +  AA     A     AAA  A A A A + A    
Sbjct: 909  AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAA 968

Query: 133  VDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185
            V    A      A    P V APA AQ SA  +  TQ     P   P   P P
Sbjct: 969  VQVAPAAPAPVPAPALVP-VPAPAAAQASAPAQ--TQAPTSAPAVAPTPAPTP 1018



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 37/111 (33%), Positives = 45/111 (40%), Gaps = 5/111 (4%)

Query: 75   AAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVD 134
            AAA A A++ A A       S  S  A    A A AA + A  A A   A  +   V V 
Sbjct: 932  AAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPAL---VPVP 988

Query: 135  AGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKP 185
            A AA +    A  + P   APA A P+ A      V Q   P  P + P P
Sbjct: 989  APAAAQASAPAQTQAP-TSAPAVA-PTPAPTPTPAVAQAEVPASPATGPGP 1037


>gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 499

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 41/223 (18%)

Query: 17  PMRS---LGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADW--- 70
           P+RS   LG G R     PR  A+  A  PS +    G GRGT G+G     L+  +   
Sbjct: 262 PLRSGPPLGAGSR-----PR--ALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLITYRVL 313

Query: 71  --------GGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEA 122
                    GG  A+  +++        +R G    +  + W+      A     +    
Sbjct: 314 SNLRRTLCSGGGVASMRISVGRG-----LRAGPRAPDAGSFWDPNPQTLAPHPQASRRPR 368

Query: 123 TAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLP--- 179
              +++ Q     G        AG   P + AP+P + +       +V +RP P  P   
Sbjct: 369 AGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 428

Query: 180 ---PSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPV 219
               S P+P+  L P        R+  +SSGH      S RP+
Sbjct: 429 NPATSSPRPLGPLRP--------RAGGQSSGHPDRTVTSPRPI 463


>gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 499

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 41/223 (18%)

Query: 17  PMRS---LGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADW--- 70
           P+RS   LG G R     PR  A+  A  PS +    G GRGT G+G     L+  +   
Sbjct: 262 PLRSGPPLGAGSR-----PR--ALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLITYRVL 313

Query: 71  --------GGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEA 122
                    GG  A+  +++        +R G    +  + W+      A     +    
Sbjct: 314 SNLRRTLCSGGGVASMRISVGRG-----LRAGPRAPDAGSFWDPNPQTLAPHPQASRRPR 368

Query: 123 TAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLP--- 179
              +++ Q     G        AG   P + AP+P + +       +V +RP P  P   
Sbjct: 369 AGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 428

Query: 180 ---PSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPV 219
               S P+P+  L P        R+  +SSGH      S RP+
Sbjct: 429 NPATSSPRPLGPLRP--------RAGGQSSGHPDRTVTSPRPI 463


>gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 536

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 54/223 (24%), Positives = 83/223 (37%), Gaps = 41/223 (18%)

Query: 17  PMRS---LGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADW--- 70
           P+RS   LG G R     PR  A+  A  PS +    G GRGT G+G     L+  +   
Sbjct: 299 PLRSGPPLGAGSR-----PR--ALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLITYRVL 350

Query: 71  --------GGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEA 122
                    GG  A+  +++        +R G    +  + W+      A     +    
Sbjct: 351 SNLRRTLCSGGGVASMRISVGRG-----LRAGPRAPDAGSFWDPNPQTLAPHPQASRRPR 405

Query: 123 TAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLP--- 179
              +++ Q     G        AG   P + AP+P + +       +V +RP P  P   
Sbjct: 406 AGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 465

Query: 180 ---PSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPV 219
               S P+P+  L P        R+  +SSGH      S RP+
Sbjct: 466 NPATSSPRPLGPLRP--------RAGGQSSGHPDRTVTSPRPI 500


>gi|24497554 homeobox A13 [Homo sapiens]
          Length = 388

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 39/107 (36%), Positives = 45/107 (42%), Gaps = 6/107 (5%)

Query: 62  SGGSLVAD-----WGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAA 116
           +GG LVAD       G AAAAAA A A A A +        +  AA       AAA AAA
Sbjct: 22  NGGGLVADELNKNMEGAAAAAAAAA-AAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAA 80

Query: 117 KAEAEATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAA 163
            A A      +A    +  GAA       GE  P   A A A  +AA
Sbjct: 81  AAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAA 127



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 6/131 (4%)

Query: 28  SLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPA 87
           ++ G    A  AA   +    G G       +     S+ A     AAAAA     L   
Sbjct: 34  NMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAH 93

Query: 88  LSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGE 147
            + +  G++ +  +A  EA   AAA AAA A A A A   +      +G  G P   AG 
Sbjct: 94  PAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAAS-----SSGGPG-PAGPAGA 147

Query: 148 EQPKVLAPAPA 158
           E  K  +P  A
Sbjct: 148 EAAKQCSPCSA 158



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 28/90 (31%), Positives = 34/90 (37%), Gaps = 8/90 (8%)

Query: 94  GSSESELAARWEAEAVAAAKAAAKAEAEA--------TAETVAEQVRVDAGAAGEPECKA 145
           G    EL    E  A AAA AAA A A A         A        V A AA      A
Sbjct: 25  GLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAA 84

Query: 146 GEEQPKVLAPAPAQPSAAEEGNTQVLQRPP 175
            + +  +  PAP  P AA   ++   + PP
Sbjct: 85  NQCRNLMAHPAPLAPGAASAYSSAPGEAPP 114


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,625,944
Number of Sequences: 37866
Number of extensions: 1874043
Number of successful extensions: 16314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 13792
Number of HSP's gapped (non-prelim): 2612
length of query: 800
length of database: 18,247,518
effective HSP length: 110
effective length of query: 690
effective length of database: 14,082,258
effective search space: 9716758020
effective search space used: 9716758020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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