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Search of human proteins with 21264602
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264602 laminin alpha 5 [Homo sapiens]
(3695 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264602 laminin alpha 5 [Homo sapiens] 7752 0.0
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 1419 0.0
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 1419 0.0
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 760 0.0
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 709 0.0
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 677 0.0
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 673 0.0
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 673 0.0
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 513 e-144
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 475 e-133
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 469 e-131
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 469 e-131
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 402 e-111
gi|219842266 usherin isoform B [Homo sapiens] 394 e-108
gi|219842259 usherin isoform A [Homo sapiens] 394 e-108
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 385 e-106
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 324 1e-87
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 323 1e-87
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 323 1e-87
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 323 1e-87
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 293 2e-78
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 293 2e-78
gi|143770880 laminin, beta 4 [Homo sapiens] 285 4e-76
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 283 2e-75
gi|148613884 netrin 1 [Homo sapiens] 254 8e-67
gi|93204871 netrin 4 [Homo sapiens] 236 4e-61
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 223 3e-57
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 216 3e-55
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 208 7e-53
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 204 1e-51
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 7752 bits (20115), Expect = 0.0
Identities = 3695/3695 (100%), Positives = 3695/3695 (100%)
Query: 1 MAKRLCAGSALCVRGPRGPAPLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAA 60
MAKRLCAGSALCVRGPRGPAPLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAA
Sbjct: 1 MAKRLCAGSALCVRGPRGPAPLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAA 60
Query: 61 SATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNA 120
SATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNA
Sbjct: 61 SATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNA 120
Query: 121 IDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGR 180
IDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGR
Sbjct: 121 IDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGR 180
Query: 181 TYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG 240
TYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG
Sbjct: 181 TYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG 240
Query: 241 AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRC 300
AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRC
Sbjct: 241 AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRC 300
Query: 301 VCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
VCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN
Sbjct: 301 VCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
Query: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL
Sbjct: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
Query: 421 DSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSND 480
DSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSND
Sbjct: 421 DSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSND 480
Query: 481 TREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQP 540
TREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQP
Sbjct: 481 TREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQP 540
Query: 541 CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD 600
CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD
Sbjct: 541 CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD 600
Query: 601 EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA
Sbjct: 601 EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
Query: 661 CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC 720
CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC
Sbjct: 661 CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC 720
Query: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDL 780
EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDL
Sbjct: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDL 780
Query: 781 RGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS 840
RGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS
Sbjct: 781 RGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS 840
Query: 841 CEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFEN 900
CEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFEN
Sbjct: 841 CEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFGFNPLEFEN 900
Query: 901 FSWRGYAQMAPVQPRIVARLNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANC 960
FSWRGYAQMAPVQPRIVARLNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANC
Sbjct: 901 FSWRGYAQMAPVQPRIVARLNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANC 960
Query: 961 TAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPGTWALRVEAEGVLLDYVVLLPSAYYEA 1020
TAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPGTWALRVEAEGVLLDYVVLLPSAYYEA
Sbjct: 961 TAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPGTWALRVEAEGVLLDYVVLLPSAYYEA 1020
Query: 1021 ALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQL 1080
ALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQL
Sbjct: 1021 ALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDGFPSAAGLEALCRQDNSLPRPCPTEQL 1080
Query: 1081 SPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQEVGVAVHTPQRAPQQGLL 1140
SPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQEVGVAVHTPQRAPQQGLL
Sbjct: 1081 SPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVEYANEDARQEVGVAVHTPQRAPQQGLL 1140
Query: 1141 SLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQARFFLHGVTLVPIEEFSPEFV 1200
SLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQARFFLHGVTLVPIEEFSPEFV
Sbjct: 1141 SLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVRLTAEQARFFLHGVTLVPIEEFSPEFV 1200
Query: 1201 EPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSP 1260
EPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSP
Sbjct: 1201 EPRVSCISSHGAFGPNSAACLPSRFPKPPQPIILRDCQVIPLPPGLPLTHAQDLTPAMSP 1260
Query: 1261 AGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLIN 1320
AGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLIN
Sbjct: 1261 AGPRPRPPTAVDPDAEPTLLREPQATVVFTTHVPTLGRYAFLLHGYQPAHPTFPVEVLIN 1320
Query: 1321 AGRVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVP 1380
AGRVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVP
Sbjct: 1321 AGRVWQGHANASFCPHGYGCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVP 1380
Query: 1381 ENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGC 1440
ENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGC
Sbjct: 1381 ENVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGC 1440
Query: 1441 HEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCIC 1500
HEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCIC
Sbjct: 1441 HEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCIC 1500
Query: 1501 PPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRR 1560
PPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRR
Sbjct: 1501 PPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRR 1560
Query: 1561 CDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAA 1620
CDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAA
Sbjct: 1561 CDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAA 1620
Query: 1621 NPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRH 1680
NPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRH
Sbjct: 1621 NPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRH 1680
Query: 1681 VPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGN 1740
VPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGN
Sbjct: 1681 VPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGN 1740
Query: 1741 QMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFS 1800
QMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFS
Sbjct: 1741 QMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFS 1800
Query: 1801 QISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR 1860
QISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR
Sbjct: 1801 QISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR 1860
Query: 1861 CVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVP 1920
CVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVP
Sbjct: 1861 CVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVP 1920
Query: 1921 SNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL 1980
SNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL
Sbjct: 1921 SNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL 1980
Query: 1981 FSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHC 2040
FSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHC
Sbjct: 1981 FSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHC 2040
Query: 2041 LCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR 2100
LCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR
Sbjct: 2041 LCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR 2100
Query: 2101 ECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGH 2160
ECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGH
Sbjct: 2101 ECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGH 2160
Query: 2161 SIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLR 2220
SIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLR
Sbjct: 2161 SIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLR 2220
Query: 2221 SPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLA 2280
SPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLA
Sbjct: 2221 SPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLA 2280
Query: 2281 AIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEA 2340
AIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEA
Sbjct: 2281 AIRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEA 2340
Query: 2341 ELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQE 2400
ELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQE
Sbjct: 2341 ELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQE 2400
Query: 2401 LNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAAS 2460
LNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAAS
Sbjct: 2401 LNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAAS 2460
Query: 2461 LDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIE 2520
LDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIE
Sbjct: 2461 LDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIE 2520
Query: 2521 ASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQ 2580
ASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQ
Sbjct: 2521 ASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQ 2580
Query: 2581 QRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQ 2640
QRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQ
Sbjct: 2581 QRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQ 2640
Query: 2641 DTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSIL 2700
DTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSIL
Sbjct: 2641 DTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSIL 2700
Query: 2701 ENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYT 2760
ENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYT
Sbjct: 2701 ENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYT 2760
Query: 2761 ALKFYLQGPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSI 2820
ALKFYLQGPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSI
Sbjct: 2761 ALKFYLQGPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSI 2820
Query: 2821 DEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGG 2880
DEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGG
Sbjct: 2821 DEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGG 2880
Query: 2881 YPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWL 2940
YPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWL
Sbjct: 2881 YPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWL 2940
Query: 2941 TDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVL 3000
TDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVL
Sbjct: 2941 TDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVL 3000
Query: 3001 LYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELA 3060
LYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELA
Sbjct: 3001 LYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELA 3060
Query: 3061 DAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL 3120
DAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL
Sbjct: 3061 DAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL 3120
Query: 3121 VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR 3180
VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR
Sbjct: 3121 VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR 3180
Query: 3181 VSLQLLRTEVKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQPEG 3240
VSLQLLRTEVKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQPEG
Sbjct: 3181 VSLQLLRTEVKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQPEG 3240
Query: 3241 PPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAPALQAQT 3300
PPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAPALQAQT
Sbjct: 3241 PPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAPALQAQT 3300
Query: 3301 PGLGPRGLQATARKASRRSRQPARHPACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARH 3360
PGLGPRGLQATARKASRRSRQPARHPACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARH
Sbjct: 3301 PGLGPRGLQATARKASRRSRQPARHPACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARH 3360
Query: 3361 RNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRS 3420
RNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRS
Sbjct: 3361 RNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRS 3420
Query: 3421 RPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSK 3480
RPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSK
Sbjct: 3421 RPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSK 3480
Query: 3481 LPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATL 3540
LPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATL
Sbjct: 3481 LPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATL 3540
Query: 3541 PDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVL 3600
PDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVL
Sbjct: 3541 PDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVL 3600
Query: 3601 CDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA 3660
CDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA
Sbjct: 3601 CDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA 3660
Query: 3661 YCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA 3695
YCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA
Sbjct: 3661 YCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA 3695
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 1419 bits (3674), Expect = 0.0
Identities = 704/1598 (44%), Positives = 932/1598 (58%), Gaps = 128/1598 (8%)
Query: 429 CNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPA 488
CN ++ + + RC C+ + GE CD C G+ + + PA
Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYN---------------QRRWRPA 345
Query: 489 GQIVNCDCSAAGTQGNA--CRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSP 546
+ +C A G+A C DP V R N QG + G C CQ ++
Sbjct: 346 AWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAG-------GGVCINCQHNTA 398
Query: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFH---FPLCQLCGCSPAGTLPE---GCD 600
GV C++CA GY+ P+ GC P PE GC+
Sbjct: 399 GV---------------------NCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE 437
Query: 601 E-AGRCLCQPEFAGPHCDRCRPGYHGFPNC---------------------QACTCDPRG 638
+ +GRC C+P F G +C++C GY+ FP C + C C+ G
Sbjct: 438 QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEG 497
Query: 639 ALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSC 698
L ++C A G C CRPG G C C GF+ FP C C CSA GS C +GQC C
Sbjct: 498 VLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCEC 557
Query: 699 RPRVTGLRCDTCVPGAYNFPYCEAGS--CHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756
RP VTG RCD C+ GAY+FP+C+ S C PAG + C C+ HVEGP+C
Sbjct: 558 RPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGY------CQCKLHVEGPTCS 611
Query: 757 RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFF 816
RCK +W L NP GC+ C C GT+ G EC+ G G C CK HV G +C +C+DG+F
Sbjct: 612 RCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Query: 817 GLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRL 876
L++++YFGC+ C+CDIGGAL C +GVC+CR + G C P ++Y PDLHH++
Sbjct: 672 ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKY 731
Query: 877 ELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNL--TSPDLFWLVFRY 934
E+E+ +TP G +RFGF+PL F FSWRGYAQM VQ + LN+ +S LF ++ RY
Sbjct: 732 EIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRY 791
Query: 935 VNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPG 994
VN G +VSG +++ +A QS+ + F PS EPAF+TVP GF +PF + PG
Sbjct: 792 VNPGTEAVSGHITIYPSWGAA-------QSKEIIFLPSKEPAFVTVPGNGFADPFSITPG 844
Query: 995 TWALRVEAEGVLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDG 1054
W ++AEGVLLDY+VLLP YYEA++LQL VTE C Y Q+ NCLLY HLP+
Sbjct: 845 IWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQE---NCLLYQHLPVTR 901
Query: 1055 FPSAAGLEALCRQDNSLPRPCPTEQLSPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVE 1114
FP EA + PRP Q +P+HP ++ +G +V++ L++ +PQ G Y +VVE
Sbjct: 902 FPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVE 961
Query: 1115 YANEDARQEVGVAVHTPQRAPQQGLLSLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVR 1174
Y+ E A+ V + G ++++ C YS LCR D +A++ L ++A ++
Sbjct: 962 YSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADIQ 1021
Query: 1175 LTAEQARFFLHGVTLVPIEEFSPEFVEPRVSCISSHGAFGPNSAACLPSRFPKPPQPIIL 1234
L ARF LH V ++PIEEFS E+V P+V CI+S+G F SA C+ PP +IL
Sbjct: 1022 LKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALIL 1081
Query: 1235 RDCQVIPLPPGLPLTHAQDLTPAMSPAGPRPRPPTAVDPDAEPTL-LREPQATVVFTTHV 1293
+ G P H P+ P+ D P + L+ PQ V V
Sbjct: 1082 ------DVLSGRPFPHL-----------PQQSSPSV---DVLPGVTLKAPQNQVTLRGRV 1121
Query: 1294 PTLGRYAFLLHGYQPAHPTFPVEVLINAGRVWQGHANASFCPHGYGCRTLVVCEGQALLD 1353
P LGRY F++H YQ AHPTFP +V ++ G G +ASFCPH GCR V+ EGQ D
Sbjct: 1122 PHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFD 1181
Query: 1354 VTHSELTVTVRVPKGRWLWLDYVLVVPENVYSFGYLREEPLDKSYDFISHCAAQGYHISP 1413
++ E+ TV+VP+G+ L L VLVVP Y + L ++ +DKS +FI++C +++ P
Sbjct: 1182 ISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDP 1241
Query: 1414 SSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCAT 1473
++S FC+N+A SL FY+ GA PC CH GATGP C P GGQCPC +VIGR C+RCAT
Sbjct: 1242 QTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCAT 1301
Query: 1474 GYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGP 1533
G++GFP C+PC CG RLC+E+TGQC CPPRT+ P C +C+ +F HP+ GCE CNCS
Sbjct: 1302 GHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRR 1361
Query: 1534 GIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLT 1593
G E P CD DSGQC+C+P +TGR+CD C+ GF+ +P C PC+C+ GT PGVCDP T
Sbjct: 1362 GTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGT 1421
Query: 1594 GQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGW 1653
G C CKENV+G +C+ C G+F LD AN KGCT CFCFG +C SS R +FVDM GW
Sbjct: 1422 GACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGW 1481
Query: 1654 VLLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLR 1713
L + DR +P PG+ + ADL+ +P + A W AP SYLGD+VSSYGG L
Sbjct: 1482 HLETADRVDIPVSFNPGSNSMVADLQELPATIHSA----SWVAPTSYLGDKVSSYGGYLT 1537
Query: 1714 YELHSETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTE 1773
Y+ S GD+ V +E +PDV L G MSI + E P P +H G++ +VEGNFRH
Sbjct: 1538 YQAKSFGLPGDM-VLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHAS 1596
Query: 1774 TRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLC 1833
+R VSREELM VL+ L ++I+ L+ + + L V LE AS G G +A VE+C C
Sbjct: 1597 SRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICAC 1656
Query: 1834 PASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCE 1893
P +Y GDSCQ C+PG+YRD KGL+ GRCVPC C+GHS++C GSG+CV+CQHNT G HCE
Sbjct: 1657 PPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCE 1716
Query: 1894 RCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAP 1953
RCQ G+ + S C +CPCP +N+FA GCV+ GG +C CK GY G CERCAP
Sbjct: 1717 RCQEGYYGNAVHGS--CRACPCP---HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAP 1771
Query: 1954 GFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGAC 1991
G+FGNP G SCQPC C+ NG C PLTG C
Sbjct: 1772 GYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDC 1805
Score = 781 bits (2018), Expect = 0.0
Identities = 381/709 (53%), Positives = 461/709 (65%), Gaps = 32/709 (4%)
Query: 19 PAPLLLVGLALLGA--ARAREE-AGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPR 75
P PLLL+ L +L A A AR+ A G SLHP YFNLAE ARI A+ATCGE P G P+
Sbjct: 18 PTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQ 77
Query: 76 PTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAIDGTERWWQSPPLSR 135
P +LYCKLVGGP A G TI+GQ+CD C + + KAHP +NAIDG+ERWWQSPPLS
Sbjct: 78 P--ELYCKLVGGPTAPGS-GHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSS 134
Query: 136 GLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDC 195
G +YN VN+TLDLGQ+FHVAY+LIKFANSPRPDLWVLERS+DFG TY PWQ+FA SK DC
Sbjct: 135 GTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDC 194
Query: 196 LERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTK 255
L+ FG + +TRDD +C TEYSRIVPLENGE+VVSL+NGRPGA NF++S LREFTK
Sbjct: 195 LKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTK 254
Query: 256 ATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPT 315
ATN+RLRFLRTNTLLGHL+ KA RDPTVTRRYYYSIKDISIGG+CVC+GHA+ C+ +P
Sbjct: 255 ATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE 314
Query: 316 DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVD 375
FR C CQH+TCG TCDRCC G+NQ+ W+PA ++EC++CNC+GHA++CYYDP+V+
Sbjct: 315 KLFR--CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVE 372
Query: 376 RRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDF 435
R++AS + G Y GGGVCI+CQH+T GVNCE+C G+YR P+D+P C C+C+ +
Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
Query: 436 TDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP-AGQIVNC 494
DG CE +GRC+C+PNF G+ C+ CA G+ FP C P T P AG I C
Sbjct: 433 ADG-CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
Query: 495 DCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG-PGCQPCQCSSPGVADDRC 553
DC+ G C GRCLC+P +G C+ C GFY P CQ C CS+ G C
Sbjct: 492 DCNLEGVLPEICDAH---GRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPC 548
Query: 554 DPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQ--LCGCSPAGTLPEGCDEAGRCLCQPEF 611
TGQC CR G G CDRC G + FP CQ C PAGT+ G C C+
Sbjct: 549 SSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTIN---SNLGYCQCKLHV 605
Query: 612 AGPHCDRCRPGYHGF-----PNCQACTCDPRGALDQL--CGAG-GLCRCRPGYTGTACQE 663
GP C RC+ Y C C C G + C G G C C+ G +C
Sbjct: 606 EGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665
Query: 664 CSPGF-----HGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
C G+ + C C C G+L + C SG C CR V G C
Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVC 714
Score = 770 bits (1988), Expect = 0.0
Identities = 563/1793 (31%), Positives = 865/1793 (48%), Gaps = 151/1793 (8%)
Query: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSS-CQPCDCSGNGDPNLLFSDCDPLTGACRGCL 1995
C C P YAG SC+ C+PG++ + L + C PC+C+G+ + C +G C C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN------QCQDGSGICVNCQ 1707
Query: 1996 RHTTGPRCEICAPGFYGNALLPGNCTRCDC--TPCGTEACDPHSG--HCLCKAGVTGRRC 2051
+T G CE C G+YGNA + G+C C C T C + G C CKAG TG +C
Sbjct: 1708 HNTAGEHCERCQEGYYGNA-VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC 1766
Query: 2052 DRCQEGHFGFDG--CGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 2109
+RC G+FG G C+PC+C + CHP +G C + + ++ +P
Sbjct: 1767 ERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC------INQEPKDSSP----- 1815
Query: 2110 PEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDH 2169
E CD C D
Sbjct: 1816 -----------------------------AEECDDC----------------------DS 1824
Query: 2170 CVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHET 2229
CV+ LL+DL G L + QL+G++AS+ ++ + DL++QL +
Sbjct: 1825 CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNH 1884
Query: 2230 AQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTL 2289
++E LE++ T L Q+ L +A +A L AK L I+ V R +
Sbjct: 1885 GSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNV 1944
Query: 2290 SELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLL 2349
L+ Q + PSG+ R AE +R++ E+R R+ G AEA+ +Q LL
Sbjct: 1945 HILLKQISGTDGEGNNVPSGD-FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLL 2003
Query: 2350 ARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERL 2409
R++ + EN LA RD L ++EA L DLR L A ++A LN N+ L
Sbjct: 2004 NRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERAL 2063
Query: 2410 EEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLL 2469
++ +E++ + L A +L L ++++++E E+LAASL+ AR L
Sbjct: 2064 GAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELS 2123
Query: 2470 QRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRIL 2529
+++ S + K LVE AE HA+ L +LA L I + + D L + A++A+ AY IL
Sbjct: 2124 DKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENIL 2183
Query: 2530 QAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWA 2588
A++AAEDAA +A ++ TV+++ L +A+ L +NS L EA + +++ V
Sbjct: 2184 NAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSP 2243
Query: 2589 ALQGARTQLRDVRAKKDQLEAHIQAAQ-AMLAMDTDETSKKIAHAKAVAAEAQDTATRVQ 2647
AL + L V +K+ ++ ++ + + + + I+ AK++ +A D V
Sbjct: 2244 ALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVL 2303
Query: 2648 SQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHN 2707
L +Q +VER + Y + +D +A+ DA +SV+ L LP L K+ + + +
Sbjct: 2304 DGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPL 2363
Query: 2708 ASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQ 2767
+ +S ++ R+RELI QAR AASKV VPM+FNG+SGV++R P DL DL YT+L +LQ
Sbjct: 2364 GN--ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQ 2421
Query: 2768 GPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQ 2827
P GTE+ FVMY+G++ A+ DY+G+++ D ++ VY LG+ A L +D+ + +
Sbjct: 2422 RPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR-EAELQVDQILTKS 2480
Query: 2828 ------FAAVSLDRTLQFGHMSVTVERQMIQ-ETKG--DTVAPGAEGLLNLRPDDFVFYV 2878
V R QF ++ T + ET G D + LLNL P++ VFYV
Sbjct: 2481 ETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYV 2540
Query: 2879 GGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDP 2938
GGYP F P L FP Y+GCIE+D LNE V+SLYNF++TF L+T PC R K
Sbjct: 2541 GGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE--- 2597
Query: 2939 WLTDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSL 2998
+D +Y +GTG+AR+ + F Q ++ G+LFF + +F+ L +++G L
Sbjct: 2598 --SDKNYFEGTGYARVPTQPH-APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKL 2654
Query: 2999 VLLYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLE 3058
++ Y + L K + +IQ+ +G +KR+ + V+ V + D ++
Sbjct: 2655 MVRYKLNSELPKERGVGDAIN-NGRDHSIQI-KIGKLQKRMWINVD---VQNTIIDGEVF 2709
Query: 3059 LADAYYLGGVPPDQLPPSLRRLFP-TGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTA 3117
YYLGG+ P ++R F + + RGC+K +K V L +T GV+ C+
Sbjct: 2710 DFSTYYLGGI-----PIAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVGVTKKCSE 2762
Query: 3118 DLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQ 3177
D + R+ +F G L + P T ++ + FGF + Q S +L + QV+L+
Sbjct: 2763 DWKLVRSASFSRGGQLSFTDLGLPP-TDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLE 2821
Query: 3178 QGRVSLQLLRTE---VKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPEL 3234
G + L + K+ + DG HYV+ S+ +G+ L +DDQL + L
Sbjct: 2822 DGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS------KRL 2875
Query: 3235 QPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST-GCA 3293
+ L LGG NF GCISNVFVQRL V DL N +VS GC+
Sbjct: 2876 KHISSSRQSLRLGG-------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCS 2928
Query: 3294 ---PALQAQTPGLGPRGLQATARKASRRSRQPARHP--------ACMLPPHLRTTRDSYQ 3342
P G T R P P AC P + + Q
Sbjct: 2929 LNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQ 2988
Query: 3343 FGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFV 3402
FG +SHL F + ++ + SSRGL+ T + +AL+LS G V
Sbjct: 2989 FGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG---TKNSFMALYLSKGRLV 3045
Query: 3403 AQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHP 3462
+ G +LR +S+++ G+WH V + + LV DG RA +EG +
Sbjct: 3046 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRA--REGSLPGNSTISIR 3103
Query: 3463 QPHTLFVGGLPASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGL 3522
P L G P S LP T F GC+K +L +PL P+ GV+ C+ GPLE G+
Sbjct: 3104 APVYL---GSPPSGKPKSLP-TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGI 3159
Query: 3523 FFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLR 3582
+F GG + L P+ L +RP ++TG++ H+G ++ +L + + +V
Sbjct: 3160 YFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG-SQPGKHLCVYLEAGKVTAS 3218
Query: 3583 ADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAP 3642
D GAG STSVT LCDGQWH +AV ++L LE+D S++T G + A P
Sbjct: 3219 MDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEP 3278
Query: 3643 LYLGGLPEPMAVQPWP--PAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCP 3693
L+LGG P + P ++ GC+R + VN PV +T ++EV G V +GCP
Sbjct: 3279 LHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 3331
Score = 188 bits (478), Expect = 7e-47
Identities = 116/364 (31%), Positives = 153/364 (42%), Gaps = 65/364 (17%)
Query: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRCL------------ 1874
C C G++C C G+ +R C C CHGH+ C
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 1875 ------PGSGVCVDCQHNTEGAHCERCQAGFVSSRDDP-SAP--CVSCPCPLSVPSNNFA 1925
G GVC++CQHNT G +CE+C G+ P AP C+ C C A
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC-----DPEHA 433
Query: 1926 EGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDP---NLLFS 1982
+GC GR C CKP + G +CE+CA G++ P L P + DP ++
Sbjct: 434 DGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
Query: 1983 DCD---------PLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA- 2032
DC+ G C C GPRC+ C GFY + C C C+ G+
Sbjct: 492 DCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQM 546
Query: 2033 -CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCR 2091
C +G C C+ GVTG+RCDRC G + F C G AC PA + G C C+
Sbjct: 547 PCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQG-SSSACDPA---GTINSNLGYCQCK 602
Query: 2092 PGTMGPQCRECAPGYWGLPEQ---GCRRCQC-------PGGRCDPHTGRCNCPPGLSGER 2141
GP C C YW L ++ GC C+C G C G C+C + G+
Sbjct: 603 LHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDS 662
Query: 2142 CDTC 2145
CDTC
Sbjct: 663 CDTC 666
Score = 128 bits (322), Expect = 9e-29
Identities = 79/270 (29%), Positives = 109/270 (40%), Gaps = 48/270 (17%)
Query: 1922 NNFAEGCVLRGGRT--QCLCKPGYAGASCERCAPGFFGN---PLVLGSS--CQPCDCSGN 1974
N AE C + +C C+ G +C+RC G+ P S C+ C+C G+
Sbjct: 302 NGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGH 361
Query: 1975 G-----DPNLLFSDCDPLT-------GACRGCLRHTTGPRCEICAPGFYGNALLP----G 2018
DP++ T G C C +T G CE CA G+Y +P
Sbjct: 362 ASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPD 421
Query: 2019 NCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGC-------------- 2064
C C C P + C+ SG C CK G C++C G++ F C
Sbjct: 422 GCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
Query: 2065 ----GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCP 2120
G + C C E G+C CRPG GP+C C G++ P C+ C C
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCS 539
Query: 2121 G-----GRCDPHTGRCNCPPGLSGERCDTC 2145
C TG+C C PG++G+RCD C
Sbjct: 540 ALGSYQMPCSSVTGQCECRPGVTGQRCDRC 569
Score = 125 bits (315), Expect = 6e-28
Identities = 79/244 (32%), Positives = 102/244 (41%), Gaps = 35/244 (14%)
Query: 1887 TEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGA 1946
T C+ V+ + PC P + P C GG QC C+P G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH------CSPEGG--QCPCQPNVIGR 1294
Query: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
C RCA G +G P C+PC C C+ +TG CR C T P+CE+C
Sbjct: 1295 QCTRCATGHYGFP-----RCKPCSCGRRL--------CEEMTGQCR-CPPRTVRPQCEVC 1340
Query: 2007 APGFYGNALLPGNCTRCDCTPCGT-----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGF 2061
+ + G C C+C+ GT CD SG C CK +TGR+CDRC G + F
Sbjct: 1341 ETHSFSFHPMAG-CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRF 1399
Query: 2062 DGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRC 2117
C PC C E C P +G C C+ G +C C G + L +GC C
Sbjct: 1400 P---ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
Query: 2118 QCPG 2121
C G
Sbjct: 1457 FCFG 1460
Score = 116 bits (291), Expect = 4e-25
Identities = 77/228 (33%), Positives = 93/228 (40%), Gaps = 32/228 (14%)
Query: 1862 VPCQCH---GHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLS 1918
+PC+CH C P G C CQ N G C RC G C C C
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQC-PCQPNVIGRQCTRCATGHYGF-----PRCKPCSCGRR 1317
Query: 1919 VPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
+ C G QC C P CE C F + G C+ C+CS G
Sbjct: 1318 L--------CEEMTG--QCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGTIE 1365
Query: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE--ACDPH 2036
+CD +G CR C TG +C+ CA GFY C C+C GTE CDP
Sbjct: 1366 AAMPECDRDSGQCR-CKPRITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPG 1420
Query: 2037 SGHCLCKAGVTGRRCDRCQEGHFGFDGCG--GCRPCACGPAAEGSECH 2082
+G CLCK V G C+ C+EG F D GC C C ++CH
Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC--FGVNNQCH 1466
Score = 115 bits (288), Expect = 8e-25
Identities = 75/238 (31%), Positives = 96/238 (40%), Gaps = 37/238 (15%)
Query: 369 YYDPEVDRR---RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
Y DP+ R +++SL Y G + C+ H TG C P + P P
Sbjct: 1238 YLDPQTASRFCKNSARSLVAFYHKGA--LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQ 1295
Query: 426 CRRC--------NCE-SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPS 476
C RC C+ CE++TG+C C P +C+VC F
Sbjct: 1296 CTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFH------- 1348
Query: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNA---CRKDPRVGRCLCKPNFQGTHCELCAPGF 533
P C+CS GT A C +D G+C CKP G C+ CA GF
Sbjct: 1349 ----------PMAGCEGCNCSRRGTIEAAMPECDRDS--GQCRCKPRITGRQCDRCASGF 1396
Query: 534 YG-PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCS 590
Y P C PC C+ G CDP TG C C+ EG C+ C G FH L GC+
Sbjct: 1397 YRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
Score = 114 bits (284), Expect = 2e-24
Identities = 63/189 (33%), Positives = 77/189 (40%), Gaps = 22/189 (11%)
Query: 1968 PCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTP 2027
PC+C G C P G C C + G +C CA G YG RC
Sbjct: 1265 PCECHPTGATG---PHCSPEGGQCP-CQPNVIGRQCTRCATGHYG-------FPRCKPCS 1313
Query: 2028 CGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPA----AEGSECHP 2083
CG C+ +G C C +C+ C+ F F GC C C A EC
Sbjct: 1314 CGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
Query: 2084 QSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLS 2138
SGQC C+P G QC CA G++ PE C C C G CDP TG C C +
Sbjct: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVE 1431
Query: 2139 GERCDTCSQ 2147
G C+ C +
Sbjct: 1432 GTECNVCRE 1440
Score = 99.0 bits (245), Expect = 8e-20
Identities = 67/233 (28%), Positives = 86/233 (36%), Gaps = 68/233 (29%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
QC CQ N G C RC G P C+ C+C RR
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSC--------------GRRLC 1319
Query: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT- 439
+ + G + C T CE C + HP+ C CNC T
Sbjct: 1320 EEMTGQCR-------CPPRTVRPQCEVCETHSFSF--HPMAG---CEGCNCSRRGTIEAA 1367
Query: 440 ---CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDC 496
C+ +G+C C+P +G +CD CA GF FP C P C+C
Sbjct: 1368 MPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP--------------------CNC 1407
Query: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG------PGCQPCQC 543
+ GT+ C DP G CLCK N +GT C +C G + GC C C
Sbjct: 1408 NRDGTEPGVC--DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 93.6 bits (231), Expect = 3e-18
Identities = 51/169 (30%), Positives = 74/169 (43%), Gaps = 22/169 (13%)
Query: 515 CLCKPNFQGTHCELCAPGFYGPG-------CQPCQCSSPGVADDRCDPDTGQC-RCRVGF 566
C C P + G C+ C+PG+Y C PC C+ ++C +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHS---NQCQDGSGICVNCQHNT 1710
Query: 567 EGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDEAG---RCLCQPEFAGPHCDRCR 620
G C+RC GY+ + C+ C C + GC G RC C+ + G C+RC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 621 PGYHGFP-----NCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
PGY G P +CQ C+C+ G L G C + + +EC
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEEC 1819
Score = 90.9 bits (224), Expect = 2e-17
Identities = 50/166 (30%), Positives = 71/166 (42%), Gaps = 35/166 (21%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
C C G +C C PG+ ++ C CNC GH+ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------ 1697
Query: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCE 441
G G+C++CQH+T G +CERC G+Y + H CR C C + T
Sbjct: 1698 ------DGSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGC 1746
Query: 442 DLTG---RCYCRPNFSGERCDVCAEGFTGFP-----SCYPTPSSSN 479
+ G RC C+ ++G +C+ CA G+ G P SC P +SN
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN 1792
Score = 89.0 bits (219), Expect = 8e-17
Identities = 62/209 (29%), Positives = 83/209 (39%), Gaps = 29/209 (13%)
Query: 373 EVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE 432
EV AS + G C G +C+ C PG+YR +H C CNC
Sbjct: 1633 EVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYR--DHKGLYTGRCVPCNCN 1690
Query: 433 SDFTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQI 491
C+D +G C C+ N +GE C+ C EG+ G N G
Sbjct: 1691 GH--SNQCQDGSGICVNCQHNTAGEHCERCQEGYYG-----------NAVH------GSC 1731
Query: 492 VNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGF------YGPGCQPCQCSS 545
C C + C + RC CK + GT CE CAPG+ +G CQPC C+S
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNS 1791
Query: 546 PGVADDRCDPDTGQCRCRVGFEGATCDRC 574
G C P TG C + + + + C
Sbjct: 1792 NGQLGS-CHPLTGDCINQEPKDSSPAEEC 1819
Score = 86.3 bits (212), Expect = 5e-16
Identities = 66/254 (25%), Positives = 88/254 (34%), Gaps = 88/254 (34%)
Query: 1454 GGQCPCHA--------------------HVIGRDCSRCATGYWGFPNCRPC------DCG 1487
GGQC C+ H G C RC TGY RP +C
Sbjct: 296 GGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY-NQRRWRPAAWEQSHECE 354
Query: 1488 ARLCDELTGQCICPPRTIPPD--------------CLLCQPQTFGCHPLVGCEEC----- 1528
A C C P C+ CQ T G V CE+C
Sbjct: 355 ACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAG----VNCEQCAKGYY 410
Query: 1529 -------NCSGPGIQELTDPT----CDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRC--- 1574
+ I DP C+ SG+C C+PN G C+ C+ G++ +P C
Sbjct: 411 RPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRI 470
Query: 1575 ------------------RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFS 1616
+ CDC+ G P +CD G+C C+ V+GP+CD C G +S
Sbjct: 471 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYS 529
Query: 1617 LDAANPKGCTRCFC 1630
C C+C
Sbjct: 530 FPI-----CQACWC 538
Score = 84.3 bits (207), Expect = 2e-15
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 23/173 (13%)
Query: 1457 CPCHAHVIGRDCSRCATGYWG------FPNCRPCDCG--ARLCDELTGQCI-CPPRTIPP 1507
C C G C C+ GY+ C PC+C + C + +G C+ C T
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 1508 DCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCS 1565
C CQ +G C C C P C + G +C C+ TG +C+ C+
Sbjct: 1714 HCERCQEGYYGNAVHGSCRACPC--PHTNSFATG-CVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 1566 PGFHGYPR-----CRPCDCHEAGTAPGVCDPLTGQCY---CKENVQGPKCDQC 1610
PG+ G P+ C+PC C+ G G C PLTG C K++ +CD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 83.6 bits (205), Expect = 3e-15
Identities = 34/81 (41%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 2066 GCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRC 2124
G PC C P A G C P+ GQC C+P +G QC CA G++G P C+ C C C
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGRRLC 1319
Query: 2125 DPHTGRCNCPPGLSGERCDTC 2145
+ TG+C CPP +C+ C
Sbjct: 1320 EEMTGQCRCPPRTVRPQCEVC 1340
Score = 39.3 bits (90), Expect = 0.073
Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 2092 PGTMGPQCRECAPGYWGLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCS 2146
P T C+ A +G C+C G C P G+C C P + G +C C+
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 2147 QQH 2149
H
Sbjct: 1301 TGH 1303
Score = 35.8 bits (81), Expect = 0.81
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 320 LQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCY 369
++C+C+ G C+RC PG+ P K S C SCN G C+
Sbjct: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQK--FGGSCQPC-SCNSNGQLGSCH 1799
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 1419 bits (3674), Expect = 0.0
Identities = 704/1598 (44%), Positives = 932/1598 (58%), Gaps = 128/1598 (8%)
Query: 429 CNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPA 488
CN ++ + + RC C+ + GE CD C G+ + + PA
Sbjct: 301 CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYN---------------QRRWRPA 345
Query: 489 GQIVNCDCSAAGTQGNA--CRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSP 546
+ +C A G+A C DP V R N QG + G C CQ ++
Sbjct: 346 AWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAG-------GGVCINCQHNTA 398
Query: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFH---FPLCQLCGCSPAGTLPE---GCD 600
GV C++CA GY+ P+ GC P PE GC+
Sbjct: 399 GV---------------------NCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE 437
Query: 601 E-AGRCLCQPEFAGPHCDRCRPGYHGFPNC---------------------QACTCDPRG 638
+ +GRC C+P F G +C++C GY+ FP C + C C+ G
Sbjct: 438 QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEG 497
Query: 639 ALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSC 698
L ++C A G C CRPG G C C GF+ FP C C CSA GS C +GQC C
Sbjct: 498 VLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCEC 557
Query: 699 RPRVTGLRCDTCVPGAYNFPYCEAGS--CHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756
RP VTG RCD C+ GAY+FP+C+ S C PAG + C C+ HVEGP+C
Sbjct: 558 RPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGY------CQCKLHVEGPTCS 611
Query: 757 RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFF 816
RCK +W L NP GC+ C C GT+ G EC+ G G C CK HV G +C +C+DG+F
Sbjct: 612 RCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Query: 817 GLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRL 876
L++++YFGC+ C+CDIGGAL C +GVC+CR + G C P ++Y PDLHH++
Sbjct: 672 ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKY 731
Query: 877 ELEEAATPEGHAVRFGFNPLEFENFSWRGYAQMAPVQPRIVARLNL--TSPDLFWLVFRY 934
E+E+ +TP G +RFGF+PL F FSWRGYAQM VQ + LN+ +S LF ++ RY
Sbjct: 732 EIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRY 791
Query: 935 VNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAFPPSTEPAFITVPQRGFGEPFVLNPG 994
VN G +VSG +++ +A QS+ + F PS EPAF+TVP GF +PF + PG
Sbjct: 792 VNPGTEAVSGHITIYPSWGAA-------QSKEIIFLPSKEPAFVTVPGNGFADPFSITPG 844
Query: 995 TWALRVEAEGVLLDYVVLLPSAYYEAALLQLRVTEACTYRPSAQQSGDNCLLYTHLPLDG 1054
W ++AEGVLLDY+VLLP YYEA++LQL VTE C Y Q+ NCLLY HLP+
Sbjct: 845 IWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQE---NCLLYQHLPVTR 901
Query: 1055 FPSAAGLEALCRQDNSLPRPCPTEQLSPSHPPLITCTGSDVDVQLQVAVPQPGRYALVVE 1114
FP EA + PRP Q +P+HP ++ +G +V++ L++ +PQ G Y +VVE
Sbjct: 902 FPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVE 961
Query: 1115 YANEDARQEVGVAVHTPQRAPQQGLLSLHPCLYSTLCRGTARDTQDHLAVFHLDSEASVR 1174
Y+ E A+ V + G ++++ C YS LCR D +A++ L ++A ++
Sbjct: 962 YSTEAAQLFVVDVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADIQ 1021
Query: 1175 LTAEQARFFLHGVTLVPIEEFSPEFVEPRVSCISSHGAFGPNSAACLPSRFPKPPQPIIL 1234
L ARF LH V ++PIEEFS E+V P+V CI+S+G F SA C+ PP +IL
Sbjct: 1022 LKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALIL 1081
Query: 1235 RDCQVIPLPPGLPLTHAQDLTPAMSPAGPRPRPPTAVDPDAEPTL-LREPQATVVFTTHV 1293
+ G P H P+ P+ D P + L+ PQ V V
Sbjct: 1082 ------DVLSGRPFPHL-----------PQQSSPSV---DVLPGVTLKAPQNQVTLRGRV 1121
Query: 1294 PTLGRYAFLLHGYQPAHPTFPVEVLINAGRVWQGHANASFCPHGYGCRTLVVCEGQALLD 1353
P LGRY F++H YQ AHPTFP +V ++ G G +ASFCPH GCR V+ EGQ D
Sbjct: 1122 PHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFD 1181
Query: 1354 VTHSELTVTVRVPKGRWLWLDYVLVVPENVYSFGYLREEPLDKSYDFISHCAAQGYHISP 1413
++ E+ TV+VP+G+ L L VLVVP Y + L ++ +DKS +FI++C +++ P
Sbjct: 1182 ISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDP 1241
Query: 1414 SSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCAT 1473
++S FC+N+A SL FY+ GA PC CH GATGP C P GGQCPC +VIGR C+RCAT
Sbjct: 1242 QTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCAT 1301
Query: 1474 GYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGP 1533
G++GFP C+PC CG RLC+E+TGQC CPPRT+ P C +C+ +F HP+ GCE CNCS
Sbjct: 1302 GHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRR 1361
Query: 1534 GIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLT 1593
G E P CD DSGQC+C+P +TGR+CD C+ GF+ +P C PC+C+ GT PGVCDP T
Sbjct: 1362 GTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGT 1421
Query: 1594 GQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGW 1653
G C CKENV+G +C+ C G+F LD AN KGCT CFCFG +C SS R +FVDM GW
Sbjct: 1422 GACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGW 1481
Query: 1654 VLLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLR 1713
L + DR +P PG+ + ADL+ +P + A W AP SYLGD+VSSYGG L
Sbjct: 1482 HLETADRVDIPVSFNPGSNSMVADLQELPATIHSA----SWVAPTSYLGDKVSSYGGYLT 1537
Query: 1714 YELHSETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTE 1773
Y+ S GD+ V +E +PDV L G MSI + E P P +H G++ +VEGNFRH
Sbjct: 1538 YQAKSFGLPGDM-VLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHAS 1596
Query: 1774 TRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLC 1833
+R VSREELM VL+ L ++I+ L+ + + L V LE AS G G +A VE+C C
Sbjct: 1597 SRAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICAC 1656
Query: 1834 PASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCE 1893
P +Y GDSCQ C+PG+YRD KGL+ GRCVPC C+GHS++C GSG+CV+CQHNT G HCE
Sbjct: 1657 PPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCE 1716
Query: 1894 RCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAP 1953
RCQ G+ + S C +CPCP +N+FA GCV+ GG +C CK GY G CERCAP
Sbjct: 1717 RCQEGYYGNAVHGS--CRACPCP---HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAP 1771
Query: 1954 GFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGAC 1991
G+FGNP G SCQPC C+ NG C PLTG C
Sbjct: 1772 GYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDC 1805
Score = 781 bits (2018), Expect = 0.0
Identities = 381/709 (53%), Positives = 461/709 (65%), Gaps = 32/709 (4%)
Query: 19 PAPLLLVGLALLGA--ARAREE-AGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPR 75
P PLLL+ L +L A A AR+ A G SLHP YFNLAE ARI A+ATCGE P G P+
Sbjct: 18 PTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQ 77
Query: 76 PTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAIDGTERWWQSPPLSR 135
P +LYCKLVGGP A G TI+GQ+CD C + + KAHP +NAIDG+ERWWQSPPLS
Sbjct: 78 P--ELYCKLVGGPTAPGS-GHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSS 134
Query: 136 GLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDC 195
G +YN VN+TLDLGQ+FHVAY+LIKFANSPRPDLWVLERS+DFG TY PWQ+FA SK DC
Sbjct: 135 GTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDC 194
Query: 196 LERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTK 255
L+ FG + +TRDD +C TEYSRIVPLENGE+VVSL+NGRPGA NF++S LREFTK
Sbjct: 195 LKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTK 254
Query: 256 ATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPT 315
ATN+RLRFLRTNTLLGHL+ KA RDPTVTRRYYYSIKDISIGG+CVC+GHA+ C+ +P
Sbjct: 255 ATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPE 314
Query: 316 DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVD 375
FR C CQH+TCG TCDRCC G+NQ+ W+PA ++EC++CNC+GHA++CYYDP+V+
Sbjct: 315 KLFR--CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVE 372
Query: 376 RRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDF 435
R++AS + G Y GGGVCI+CQH+T GVNCE+C G+YR P+D+P C C+C+ +
Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
Query: 436 TDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP-AGQIVNC 494
DG CE +GRC+C+PNF G+ C+ CA G+ FP C P T P AG I C
Sbjct: 433 ADG-CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
Query: 495 DCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG-PGCQPCQCSSPGVADDRC 553
DC+ G C GRCLC+P +G C+ C GFY P CQ C CS+ G C
Sbjct: 492 DCNLEGVLPEICDAH---GRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPC 548
Query: 554 DPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQ--LCGCSPAGTLPEGCDEAGRCLCQPEF 611
TGQC CR G G CDRC G + FP CQ C PAGT+ G C C+
Sbjct: 549 SSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTIN---SNLGYCQCKLHV 605
Query: 612 AGPHCDRCRPGYHGF-----PNCQACTCDPRGALDQL--CGAG-GLCRCRPGYTGTACQE 663
GP C RC+ Y C C C G + C G G C C+ G +C
Sbjct: 606 EGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665
Query: 664 CSPGF-----HGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
C G+ + C C C G+L + C SG C CR V G C
Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVC 714
Score = 713 bits (1840), Expect = 0.0
Identities = 536/1736 (30%), Positives = 826/1736 (47%), Gaps = 164/1736 (9%)
Query: 2000 GPRCEICAPGFYGN--ALLPGNCTRCDCTPCGTEACDPHSGHCL-CKAGVTGRRCDRCQE 2056
G C+ C+PG+Y + L G C C+C + C SG C+ C+ G C+RCQE
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ-CQDGSGICVNCQHNTAGEHCERCQE 1720
Query: 2057 GHFGFDGCGGCRPCAC---GPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ- 2112
G++G G CR C C A G + +C C+ G G QC CAPGY+G P++
Sbjct: 1721 GYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 1780
Query: 2113 --GCRRCQCPG----GRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEV 2166
C+ C C G C P TG C +Q P P C+
Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCI----------------NQEPKDSSPAEE---CDD 1821
Query: 2167 CDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPR 2226
CD CV+ LL+DL G L + QL+G++AS+ ++ + DL++QL +
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
Query: 2227 HETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVD 2286
++E LE++ T L Q T + +Q+ + TL +
Sbjct: 1882 SNHGSKIEGLERELTDLN--------QEFETLQEKAQVNSRKAQTLNNN----------- 1922
Query: 2287 RTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQ 2346
N + S ++L + V R +
Sbjct: 1923 ---------------VNRATQSAKELDVKIKNVIRNV----------------------- 1944
Query: 2347 RLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQ 2406
+L R++ + EN LA RD L ++EA L DLR L A ++A LN N+
Sbjct: 1945 HMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENE 2004
Query: 2407 ERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGART 2466
L ++ +E++ + L A +L L ++++++E E+LAASL+ AR
Sbjct: 2005 RALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ 2064
Query: 2467 PLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYS 2526
L +++ S + K LVE AE HA+ L +LA L I + + D L + A++A+ AY
Sbjct: 2065 ELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYE 2124
Query: 2527 RILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGL 2585
IL A++AAEDAA +A ++ TV+++ L +A+ L +NS L EA + +++
Sbjct: 2125 NILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQE 2184
Query: 2586 VWAALQGARTQLRDVRAKKDQLEAHIQAAQ-AMLAMDTDETSKKIAHAKAVAAEAQDTAT 2644
V AL + L V +K+ ++ ++ + + + + I+ AK++ +A D
Sbjct: 2185 VSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITD 2244
Query: 2645 RVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRG 2704
V L +Q +VER + Y + +D +A+ DA +SV+ L LP L K+ + +
Sbjct: 2245 EVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQL 2304
Query: 2705 VHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKF 2764
+ + +S ++ R+RELI QAR AASKV VPM+FNG+SGV++R P DL DL YT+L
Sbjct: 2305 LPLGN--ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSL 2362
Query: 2765 YLQGPEPEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDI 2824
+LQ P GTE+ FVMY+G++ A+ DY+G+++ D ++ VY LG+ A L +D+ +
Sbjct: 2363 FLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR-EAELQVDQIL 2421
Query: 2825 GEQ------FAAVSLDRTLQFGHMSVTVERQMIQ-ETKG--DTVAPGAEGLLNLRPDDFV 2875
+ V R QF ++ T + ET G D + LLNL P++ V
Sbjct: 2422 TKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVV 2481
Query: 2876 FYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKST 2935
FYVGGYP F P L FP Y+GCIE+D LNE V+SLYNF++TF L+T PC R K
Sbjct: 2482 FYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE 2541
Query: 2936 GDPWLTDGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQE 2995
+D +Y +GTG+AR+ + F Q ++ G+LFF + +F+ L +++
Sbjct: 2542 -----SDKNYFEGTGYARVPTQPH-APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIED 2595
Query: 2996 GSLVLLYDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDN 3055
G L++ Y + L K + +IQ+ +G +KR+ + V+ V + D
Sbjct: 2596 GKLMVRYKLNSELPKERGVGDAIN-NGRDHSIQI-KIGKLQKRMWINVD---VQNTIIDG 2650
Query: 3056 DLELADAYYLGGVPPDQLPPSLRRLFP-TGGSVRGCVKGIKALGKYVDLKRLNTTGVSAG 3114
++ YYLGG+ P ++R F + + RGC+K +K V L +T GV+
Sbjct: 2651 EVFDFSTYYLGGI-----PIAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVGVTKK 2703
Query: 3115 CTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQV 3174
C+ D + R+ +F G L + P T ++ + FGF + Q S +L + QV
Sbjct: 2704 CSEDWKLVRSASFSRGGQLSFTDLGLPP-TDHLQASFGFQTFQPSGILLDHQTWTRNLQV 2762
Query: 3175 SLQQGRVSLQLLRTE---VKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPP 3231
+L+ G + L + K+ + DG HYV+ S+ +G+ L +DDQL +
Sbjct: 2763 TLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS------ 2816
Query: 3232 PELQPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST- 3290
L+ L LGG NF GCISNVFVQRL V DL N +VS
Sbjct: 2817 KRLKHISSSRQSLRLGG-------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 2869
Query: 3291 GCA---PALQAQTPGLGPRGLQATARKASRRSRQPARHP--------ACMLPPHLRTTRD 3339
GC+ P G T R P P AC P +
Sbjct: 2870 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 2929
Query: 3340 SYQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNG 3399
+ QFG +SHL F + ++ + SSRGL+ T + +AL+LS G
Sbjct: 2930 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG---TKNSFMALYLSKG 2986
Query: 3400 HFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGA 3459
V + G +LR +S+++ G+WH V + + LV DG RA +EG +
Sbjct: 2987 RLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRA--REGSLPGNSTI 3044
Query: 3460 EHPQPHTLFVGGLPASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLE 3519
P L G P S LP T F GC+K +L +PL P+ GV+ C+ GPLE
Sbjct: 3045 SIRAPVYL---GSPPSGKPKSLP-TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLE 3100
Query: 3520 AGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQV 3579
G++F GG + L P+ L +RP ++TG++ H+G ++ +L + + +V
Sbjct: 3101 KGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG-SQPGKHLCVYLEAGKV 3159
Query: 3580 LLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGA 3639
D GAG STSVT LCDGQWH +AV ++L LE+D S++T G + A
Sbjct: 3160 TASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAST 3219
Query: 3640 PAPLYLGGLPEPMAVQPWP--PAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCP 3693
PL+LGG P + P ++ GC+R + VN PV +T ++EV G V +GCP
Sbjct: 3220 QEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 3275
Score = 188 bits (478), Expect = 7e-47
Identities = 116/364 (31%), Positives = 153/364 (42%), Gaps = 65/364 (17%)
Query: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRCL------------ 1874
C C G++C C G+ +R C C CHGH+ C
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 1875 ------PGSGVCVDCQHNTEGAHCERCQAGFVSSRDDP-SAP--CVSCPCPLSVPSNNFA 1925
G GVC++CQHNT G +CE+C G+ P AP C+ C C A
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC-----DPEHA 433
Query: 1926 EGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDP---NLLFS 1982
+GC GR C CKP + G +CE+CA G++ P L P + DP ++
Sbjct: 434 DGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
Query: 1983 DCD---------PLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA- 2032
DC+ G C C GPRC+ C GFY + C C C+ G+
Sbjct: 492 DCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQM 546
Query: 2033 -CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCR 2091
C +G C C+ GVTG+RCDRC G + F C G AC PA + G C C+
Sbjct: 547 PCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQG-SSSACDPA---GTINSNLGYCQCK 602
Query: 2092 PGTMGPQCRECAPGYWGLPEQ---GCRRCQC-------PGGRCDPHTGRCNCPPGLSGER 2141
GP C C YW L ++ GC C+C G C G C+C + G+
Sbjct: 603 LHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDS 662
Query: 2142 CDTC 2145
CDTC
Sbjct: 663 CDTC 666
Score = 128 bits (322), Expect = 9e-29
Identities = 79/270 (29%), Positives = 109/270 (40%), Gaps = 48/270 (17%)
Query: 1922 NNFAEGCVLRGGRT--QCLCKPGYAGASCERCAPGFFGN---PLVLGSS--CQPCDCSGN 1974
N AE C + +C C+ G +C+RC G+ P S C+ C+C G+
Sbjct: 302 NGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGH 361
Query: 1975 G-----DPNLLFSDCDPLT-------GACRGCLRHTTGPRCEICAPGFYGNALLP----G 2018
DP++ T G C C +T G CE CA G+Y +P
Sbjct: 362 ASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPD 421
Query: 2019 NCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGC-------------- 2064
C C C P + C+ SG C CK G C++C G++ F C
Sbjct: 422 GCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSE 481
Query: 2065 ----GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCP 2120
G + C C E G+C CRPG GP+C C G++ P C+ C C
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--CQACWCS 539
Query: 2121 G-----GRCDPHTGRCNCPPGLSGERCDTC 2145
C TG+C C PG++G+RCD C
Sbjct: 540 ALGSYQMPCSSVTGQCECRPGVTGQRCDRC 569
Score = 125 bits (315), Expect = 6e-28
Identities = 79/244 (32%), Positives = 102/244 (41%), Gaps = 35/244 (14%)
Query: 1887 TEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGA 1946
T C+ V+ + PC P + P C GG QC C+P G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH------CSPEGG--QCPCQPNVIGR 1294
Query: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
C RCA G +G P C+PC C C+ +TG CR C T P+CE+C
Sbjct: 1295 QCTRCATGHYGFP-----RCKPCSCGRRL--------CEEMTGQCR-CPPRTVRPQCEVC 1340
Query: 2007 APGFYGNALLPGNCTRCDCTPCGT-----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGF 2061
+ + G C C+C+ GT CD SG C CK +TGR+CDRC G + F
Sbjct: 1341 ETHSFSFHPMAG-CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRF 1399
Query: 2062 DGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRC 2117
C PC C E C P +G C C+ G +C C G + L +GC C
Sbjct: 1400 P---ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
Query: 2118 QCPG 2121
C G
Sbjct: 1457 FCFG 1460
Score = 116 bits (291), Expect = 4e-25
Identities = 77/228 (33%), Positives = 93/228 (40%), Gaps = 32/228 (14%)
Query: 1862 VPCQCH---GHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLS 1918
+PC+CH C P G C CQ N G C RC G C C C
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQC-PCQPNVIGRQCTRCATGHYGF-----PRCKPCSCGRR 1317
Query: 1919 VPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
+ C G QC C P CE C F + G C+ C+CS G
Sbjct: 1318 L--------CEEMTG--QCRCPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGTIE 1365
Query: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE--ACDPH 2036
+CD +G CR C TG +C+ CA GFY C C+C GTE CDP
Sbjct: 1366 AAMPECDRDSGQCR-CKPRITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPG 1420
Query: 2037 SGHCLCKAGVTGRRCDRCQEGHFGFDGCG--GCRPCACGPAAEGSECH 2082
+G CLCK V G C+ C+EG F D GC C C ++CH
Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC--FGVNNQCH 1466
Score = 115 bits (288), Expect = 8e-25
Identities = 75/238 (31%), Positives = 96/238 (40%), Gaps = 37/238 (15%)
Query: 369 YYDPEVDRR---RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
Y DP+ R +++SL Y G + C+ H TG C P + P P
Sbjct: 1238 YLDPQTASRFCKNSARSLVAFYHKGA--LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQ 1295
Query: 426 CRRC--------NCE-SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPS 476
C RC C+ CE++TG+C C P +C+VC F
Sbjct: 1296 CTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFH------- 1348
Query: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNA---CRKDPRVGRCLCKPNFQGTHCELCAPGF 533
P C+CS GT A C +D G+C CKP G C+ CA GF
Sbjct: 1349 ----------PMAGCEGCNCSRRGTIEAAMPECDRDS--GQCRCKPRITGRQCDRCASGF 1396
Query: 534 YG-PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCS 590
Y P C PC C+ G CDP TG C C+ EG C+ C G FH L GC+
Sbjct: 1397 YRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCT 1454
Score = 114 bits (284), Expect = 2e-24
Identities = 63/189 (33%), Positives = 77/189 (40%), Gaps = 22/189 (11%)
Query: 1968 PCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTP 2027
PC+C G C P G C C + G +C CA G YG RC
Sbjct: 1265 PCECHPTGATG---PHCSPEGGQCP-CQPNVIGRQCTRCATGHYG-------FPRCKPCS 1313
Query: 2028 CGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPA----AEGSECHP 2083
CG C+ +G C C +C+ C+ F F GC C C A EC
Sbjct: 1314 CGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
Query: 2084 QSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLS 2138
SGQC C+P G QC CA G++ PE C C C G CDP TG C C +
Sbjct: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACLCKENVE 1431
Query: 2139 GERCDTCSQ 2147
G C+ C +
Sbjct: 1432 GTECNVCRE 1440
Score = 99.0 bits (245), Expect = 8e-20
Identities = 67/233 (28%), Positives = 86/233 (36%), Gaps = 68/233 (29%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
QC CQ N G C RC G P C+ C+C RR
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSC--------------GRRLC 1319
Query: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT- 439
+ + G + C T CE C + HP+ C CNC T
Sbjct: 1320 EEMTGQCR-------CPPRTVRPQCEVCETHSFSF--HPMAG---CEGCNCSRRGTIEAA 1367
Query: 440 ---CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDC 496
C+ +G+C C+P +G +CD CA GF FP C P C+C
Sbjct: 1368 MPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP--------------------CNC 1407
Query: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG------PGCQPCQC 543
+ GT+ C DP G CLCK N +GT C +C G + GC C C
Sbjct: 1408 NRDGTEPGVC--DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 93.6 bits (231), Expect = 3e-18
Identities = 51/169 (30%), Positives = 74/169 (43%), Gaps = 22/169 (13%)
Query: 515 CLCKPNFQGTHCELCAPGFYGPG-------CQPCQCSSPGVADDRCDPDTGQC-RCRVGF 566
C C P + G C+ C+PG+Y C PC C+ ++C +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHS---NQCQDGSGICVNCQHNT 1710
Query: 567 EGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDEAG---RCLCQPEFAGPHCDRCR 620
G C+RC GY+ + C+ C C + GC G RC C+ + G C+RC
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 621 PGYHGFP-----NCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
PGY G P +CQ C+C+ G L G C + + +EC
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEEC 1819
Score = 90.9 bits (224), Expect = 2e-17
Identities = 50/166 (30%), Positives = 71/166 (42%), Gaps = 35/166 (21%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
C C G +C C PG+ ++ C CNC GH+ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------ 1697
Query: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCE 441
G G+C++CQH+T G +CERC G+Y + H CR C C + T
Sbjct: 1698 ------DGSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGC 1746
Query: 442 DLTG---RCYCRPNFSGERCDVCAEGFTGFP-----SCYPTPSSSN 479
+ G RC C+ ++G +C+ CA G+ G P SC P +SN
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN 1792
Score = 89.0 bits (219), Expect = 8e-17
Identities = 62/209 (29%), Positives = 83/209 (39%), Gaps = 29/209 (13%)
Query: 373 EVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE 432
EV AS + G C G +C+ C PG+YR +H C CNC
Sbjct: 1633 EVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYR--DHKGLYTGRCVPCNCN 1690
Query: 433 SDFTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQI 491
C+D +G C C+ N +GE C+ C EG+ G N G
Sbjct: 1691 GH--SNQCQDGSGICVNCQHNTAGEHCERCQEGYYG-----------NAVH------GSC 1731
Query: 492 VNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGF------YGPGCQPCQCSS 545
C C + C + RC CK + GT CE CAPG+ +G CQPC C+S
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNS 1791
Query: 546 PGVADDRCDPDTGQCRCRVGFEGATCDRC 574
G C P TG C + + + + C
Sbjct: 1792 NGQLGS-CHPLTGDCINQEPKDSSPAEEC 1819
Score = 86.3 bits (212), Expect = 5e-16
Identities = 66/254 (25%), Positives = 88/254 (34%), Gaps = 88/254 (34%)
Query: 1454 GGQCPCHA--------------------HVIGRDCSRCATGYWGFPNCRPC------DCG 1487
GGQC C+ H G C RC TGY RP +C
Sbjct: 296 GGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY-NQRRWRPAAWEQSHECE 354
Query: 1488 ARLCDELTGQCICPPRTIPPD--------------CLLCQPQTFGCHPLVGCEEC----- 1528
A C C P C+ CQ T G V CE+C
Sbjct: 355 ACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAG----VNCEQCAKGYY 410
Query: 1529 -------NCSGPGIQELTDPT----CDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRC--- 1574
+ I DP C+ SG+C C+PN G C+ C+ G++ +P C
Sbjct: 411 RPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRI 470
Query: 1575 ------------------RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFS 1616
+ CDC+ G P +CD G+C C+ V+GP+CD C G +S
Sbjct: 471 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYS 529
Query: 1617 LDAANPKGCTRCFC 1630
C C+C
Sbjct: 530 FPI-----CQACWC 538
Score = 84.3 bits (207), Expect = 2e-15
Identities = 52/173 (30%), Positives = 73/173 (42%), Gaps = 23/173 (13%)
Query: 1457 CPCHAHVIGRDCSRCATGYWG------FPNCRPCDCG--ARLCDELTGQCI-CPPRTIPP 1507
C C G C C+ GY+ C PC+C + C + +G C+ C T
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 1508 DCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCS 1565
C CQ +G C C C P C + G +C C+ TG +C+ C+
Sbjct: 1714 HCERCQEGYYGNAVHGSCRACPC--PHTNSFATG-CVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 1566 PGFHGYPR-----CRPCDCHEAGTAPGVCDPLTGQCY---CKENVQGPKCDQC 1610
PG+ G P+ C+PC C+ G G C PLTG C K++ +CD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 83.6 bits (205), Expect = 3e-15
Identities = 34/81 (41%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 2066 GCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRC 2124
G PC C P A G C P+ GQC C+P +G QC CA G++G P C+ C C C
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGRRLC 1319
Query: 2125 DPHTGRCNCPPGLSGERCDTC 2145
+ TG+C CPP +C+ C
Sbjct: 1320 EEMTGQCRCPPRTVRPQCEVC 1340
Score = 39.3 bits (90), Expect = 0.073
Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 2092 PGTMGPQCRECAPGYWGLPEQGCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCS 2146
P T C+ A +G C+C G C P G+C C P + G +C C+
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 2147 QQH 2149
H
Sbjct: 1301 TGH 1303
Score = 35.8 bits (81), Expect = 0.81
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 320 LQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCY 369
++C+C+ G C+RC PG+ P K S C SCN G C+
Sbjct: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQK--FGGSCQPC-SCNSNGQLGSCH 1799
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 760 bits (1962), Expect = 0.0
Identities = 553/1730 (31%), Positives = 846/1730 (48%), Gaps = 108/1730 (6%)
Query: 2006 CAPGFYGN--ALLPGNCTRCDCTPCGTEACDPHSGHCL-CKAGVTGRRCDRCQEGHFGFD 2062
C+PG+Y + L G C C+C + C SG C+ C+ G C+RCQEG++G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ-CQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
Query: 2063 GCGGCRPCAC---GPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRR 2116
G CR C C A G + +C C+ G G QC CAPGY+G P++ C+
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
Query: 2117 CQCPG----GRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVV 2172
C C G C P TG C +Q P P C+ CD CV+
Sbjct: 178 CSCNSNGQLGSCHPLTGDCI----------------NQEPKDSSPAEE---CDDCDSCVM 218
Query: 2173 LLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQ 2232
LL+DL G L + QL+G++AS+ ++ + DL++QL + +
Sbjct: 219 TLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSK 278
Query: 2233 LEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSEL 2292
+E LE++ T L Q+ L +A +A L AK L I+ V R + L
Sbjct: 279 IEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHIL 338
Query: 2293 MSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARV 2352
+ Q + PSG+ R AE +R++ E+R R+ G AEA+ +Q LL R+
Sbjct: 339 LKQISGTDGEGNNVPSGD-FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRI 397
Query: 2353 QEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEA 2412
+ + EN LA RD L ++EA L DLR L A ++A LN N+ L
Sbjct: 398 RTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAI 457
Query: 2413 LQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRM 2472
++ +E++ + L A +L L ++++++E E+LAASL+ AR L ++
Sbjct: 458 QRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKV 517
Query: 2473 QTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAV 2532
+ S + K LVE AE HA+ L +LA L I + + D L + A++A+ AY IL A+
Sbjct: 518 RELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAI 577
Query: 2533 QAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQ 2591
+AAEDAA +A ++ TV+++ L +A+ L +NS L EA + +++ V AL
Sbjct: 578 KAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALN 637
Query: 2592 GARTQLRDVRAKKDQLEAHIQAAQ-AMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQL 2650
+ L V +K+ ++ ++ + + + + I+ AK++ +A D V L
Sbjct: 638 NLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGL 697
Query: 2651 QAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASL 2710
+Q +VER + Y + +D +A+ DA +SV+ L LP L K+ + + + +
Sbjct: 698 NPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGN- 756
Query: 2711 ALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPE 2770
+S ++ R+RELI QAR AASKV VPM+FNG+SGV++R P DL DL YT+L +LQ P
Sbjct: 757 -ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPN 815
Query: 2771 PEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQ--- 2827
GTE+ FVMY+G++ A+ DY+G+++ D ++ VY LG+ A L +D+ + +
Sbjct: 816 SRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR-EAELQVDQILTKSETK 874
Query: 2828 ---FAAVSLDRTLQFGHMSVTVERQMIQ-ETKG--DTVAPGAEGLLNLRPDDFVFYVGGY 2881
V R QF ++ T + ET G D + LLNL P++ VFYVGGY
Sbjct: 875 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 934
Query: 2882 PSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLT 2941
P F P L FP Y+GCIE+D LNE V+SLYNF++TF L+T PC R K +
Sbjct: 935 PPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE-----S 989
Query: 2942 DGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLL 3001
D +Y +GTG+AR+ + F Q ++ G+LFF + +F+ L +++G L++
Sbjct: 990 DKNYFEGTGYARVPTQPH-APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVR 1048
Query: 3002 YDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELAD 3061
Y + L K + +IQ+ +G +KR+ + V+ V + D ++
Sbjct: 1049 YKLNSELPKERGVGDAIN-NGRDHSIQI-KIGKLQKRMWINVD---VQNTIIDGEVFDFS 1103
Query: 3062 AYYLGGVPPDQLPPSLRRLFP-TGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL 3120
YYLGG+ P ++R F + + RGC+K +K V L +T GV+ C+ D
Sbjct: 1104 TYYLGGI-----PIAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVGVTKKCSEDWK 1156
Query: 3121 VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR 3180
+ R+ +F G L + P T ++ + FGF + Q S +L + QV+L+ G
Sbjct: 1157 LVRSASFSRGGQLSFTDLGLPP-TDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGY 1215
Query: 3181 VSLQLLRTE---VKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQ 3237
+ L + K+ + DG HYV+ S+ +G+ L +DDQL + L+
Sbjct: 1216 IELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS------KRLKHI 1269
Query: 3238 PEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST-GCA--- 3293
L LGG NF GCISNVFVQRL V DL N +VS GC+
Sbjct: 1270 SSSRQSLRLGG-------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNK 1322
Query: 3294 PALQAQTPGLGPRGLQATARKASRRSRQPARHP--------ACMLPPHLRTTRDSYQFGG 3345
P G T R P P AC P + + QFG
Sbjct: 1323 PPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGD 1382
Query: 3346 SLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQM 3405
+SHL F + ++ + SSRGL+ T + +AL+LS G V +
Sbjct: 1383 IPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG---TKNSFMALYLSKGRLVFAL 1439
Query: 3406 EGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPH 3465
G +LR +S+++ G+WH V + + LV DG RA +EG + P
Sbjct: 1440 GTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRA--REGSLPGNSTISIRAPV 1497
Query: 3466 TLFVGGLPASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFP 3525
L G P S LP T F GC+K +L +PL P+ GV+ C+ GPLE G++F
Sbjct: 1498 YL---GSPPSGKPKSLP-TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFS 1553
Query: 3526 GSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADD 3585
GG + L P+ L +RP ++TG++ H+G ++ +L + + +V D
Sbjct: 1554 EEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG-SQPGKHLCVYLEAGKVTASMDS 1612
Query: 3586 GAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYL 3645
GAG STSVT LCDGQWH +AV ++L LE+D S++T G + A PL+L
Sbjct: 1613 GAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHL 1672
Query: 3646 GGLPEPMAVQPWP--PAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCP 3693
GG P + P ++ GC+R + VN PV +T ++EV G V +GCP
Sbjct: 1673 GGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1722
Score = 198 bits (503), Expect = 9e-50
Identities = 85/149 (57%), Positives = 102/149 (68%), Gaps = 9/149 (6%)
Query: 1843 QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSS 1902
Q C+PG+YRD KGL+ GRCVPC C+GHS++C GSG+CV+CQHNT G HCERCQ G+ +
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 1903 RDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVL 1962
S C +CPCP +N+FA GCV+ GG +C CK GY G CERCAPG+FGNP
Sbjct: 117 AVHGS--CRACPCP---HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 171
Query: 1963 GSSCQPCDCSGNGDPNLLFSDCDPLTGAC 1991
G SCQPC C+ NG C PLTG C
Sbjct: 172 GGSCQPCSCNSNGQ----LGSCHPLTGDC 196
Score = 98.2 bits (243), Expect = 1e-19
Identities = 57/162 (35%), Positives = 79/162 (48%), Gaps = 27/162 (16%)
Query: 574 CAPGYF------HFPLCQLCGCSPAGTLPEGCDEAGRCL-CQPEFAGPHCDRCRPGYHG- 625
C+PGY+ + C C C+ G + D +G C+ CQ AG HC+RC+ GY+G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 626 --FPNCQACTCDPRGALDQLCGAGG---LCRCRPGYTGTACQECSPGFHGFP-----SCV 675
+C+AC C + C G C C+ GYTGT C+ C+PG+ G P SC
Sbjct: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
Query: 676 PCHCSAEGSLHAACDPRSGQC------SCRPRVTGLRCDTCV 711
PC C++ G L +C P +G C P CD+CV
Sbjct: 177 PCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDCDSCV 217
Score = 82.8 bits (203), Expect = 6e-15
Identities = 54/174 (31%), Positives = 72/174 (41%), Gaps = 29/174 (16%)
Query: 408 CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFT 466
C PG+YR +H C CNC C+D +G C C+ N +GE C+ C EG+
Sbjct: 59 CSPGYYR--DHKGLYTGRCVPCNCNGH--SNQCQDGSGICVNCQHNTAGEHCERCQEGYY 114
Query: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC 526
G N G C C + C + RC CK + GT C
Sbjct: 115 G-----------NAVH------GSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC 157
Query: 527 ELCAPGF------YGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRC 574
E CAPG+ +G CQPC C+S G C P TG C + + + + C
Sbjct: 158 ERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEEC 210
Score = 81.6 bits (200), Expect = 1e-14
Identities = 46/152 (30%), Positives = 66/152 (43%), Gaps = 35/152 (23%)
Query: 336 CCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCID 395
C PG+ ++ C CNC GH+ C G G+C++
Sbjct: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
Query: 396 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTG---RCYCRPN 452
CQH+T G +CERC G+Y + H CR C C + T + G RC C+
Sbjct: 97 CQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 151
Query: 453 FSGERCDVCAEGFTGFP-----SCYPTPSSSN 479
++G +C+ CA G+ G P SC P +SN
Sbjct: 152 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN 183
Score = 80.1 bits (196), Expect = 4e-14
Identities = 51/149 (34%), Positives = 68/149 (45%), Gaps = 20/149 (13%)
Query: 486 LPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG----CQP 540
L G+ V C+C+ N C+ G C+ C+ N G HCE C G+YG C+
Sbjct: 70 LYTGRCVPCNCNG---HSNQCQDGS--GICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA 124
Query: 541 CQCSSPGVADDRCDPDTG--QCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAG 593
C C C + G +C C+ G+ G C+RCAPGYF P CQ C C+ G
Sbjct: 125 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG 184
Query: 594 TLPEGCDEAGRCLCQ-PEFAGP--HCDRC 619
L G C+ Q P+ + P CD C
Sbjct: 185 QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 79.3 bits (194), Expect = 6e-14
Identities = 53/170 (31%), Positives = 71/170 (41%), Gaps = 35/170 (20%)
Query: 298 GRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN 354
GRCV C+GH++ C D + CQHNT G C+RC G+ + A S
Sbjct: 73 GRCVPCNCNGHSNQCQ-----DGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCR 123
Query: 355 ECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR 414
C + AT C GG V C+ TG CERC PG++
Sbjct: 124 ACPCPHTNSFATGC-----------------VVNGGDVRCSCKAGYTGTQCERCAPGYFG 166
Query: 415 SPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY---CRPNFSGERCDVC 461
+P S C+ C+C S+ G+C LTG C + + E CD C
Sbjct: 167 NPQKFGGS---CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 78.2 bits (191), Expect = 1e-13
Identities = 48/162 (29%), Positives = 63/162 (38%), Gaps = 16/162 (9%)
Query: 662 QECSPGFHGFPS------CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGA 714
Q CSPG++ CVPC+C+ + C SG C +C+ G C+ C G
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSN---QCQDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 715 YNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPE 771
Y C A C + V C C+A G C+RC PG++G
Sbjct: 114 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 173
Query: 772 GCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKD 813
C CSC+ G LG C P TG C + C D
Sbjct: 174 SCQPCSCNSNGQLG---SCHPLTGDCINQEPKDSSPAEECDD 212
Score = 77.8 bits (190), Expect = 2e-13
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 1448 PTCEPFGGQCPCHAHVIGRDCSRCATGYWG------FPNCRPCDCG--ARLCDELTGQCI 1499
P +P G ++V R C+ GY+ C PC+C + C + +G C+
Sbjct: 36 PFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICV 95
Query: 1500 -CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG--QCKCRPNV 1556
C T C CQ +G C C C P C + G +C C+
Sbjct: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPC--PHTNSFATG-CVVNGGDVRCSCKAGY 152
Query: 1557 TGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPGVCDPLTGQCY---CKENVQGPKCD 1608
TG +C+ C+PG+ G P+ C+PC C+ G G C PLTG C K++ +CD
Sbjct: 153 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECD 211
Query: 1609 QC 1610
C
Sbjct: 212 DC 213
Score = 69.3 bits (168), Expect = 7e-11
Identities = 46/158 (29%), Positives = 62/158 (39%), Gaps = 9/158 (5%)
Query: 710 CVPGAY-NFPYCEAGSCHPAGLAPVDPALPEAQVPCM-CRAHVEGPSCDRCKPGFWGLSP 767
C PG Y + G C P + C+ C+ + G C+RC+ G++G +
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
Query: 768 SNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCR 827
C C C + G +C CK G C C G+FG Q C+
Sbjct: 119 HG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
Query: 828 SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
C C+ G LG SC P TG C Q P S PA +
Sbjct: 177 PCSCNSNGQLG-SCHPLTGDC----INQEPKDSSPAEE 209
Score = 61.2 bits (147), Expect = 2e-08
Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 1525 CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHG---YPRCRPCDCH 1580
C CNC+G Q C SG C C+ N G C+ C G++G + CR C C
Sbjct: 75 CVPCNCNGHSNQ------CQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
Query: 1581 EAGTAPGVCDPLTG--QCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
+ C G +C CK G +C++C+ G F C C C
Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
Score = 53.5 bits (127), Expect = 4e-06
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 11/79 (13%)
Query: 1432 NNGARPCGCHEVGATGPTCEPFGG--QCPCHAHVIGRDCSRCATGYWGFP-----NCRPC 1484
+ R C C + C GG +C C A G C RCA GY+G P +C+PC
Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
Query: 1485 DCGAR----LCDELTGQCI 1499
C + C LTG CI
Sbjct: 179 SCNSNGQLGSCHPLTGDCI 197
Score = 49.7 bits (117), Expect = 5e-05
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC--HGHSDRCLPGSGVCVDCQHNTE 1888
C C A Y G C+ CAPG++ + + F G C PC C +G C P +G C++ Q +
Sbjct: 146 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCIN-QEPKD 203
Query: 1889 GAHCERC 1895
+ E C
Sbjct: 204 SSPAEEC 210
Score = 43.1 bits (100), Expect = 0.005
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 7/87 (8%)
Query: 1833 CPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC---HGHSDRCLPGSG-VCVDCQHNTE 1888
C + G+ C+ C G+Y + G C C C + + C+ G V C+
Sbjct: 97 CQHNTAGEHCERCQEGYYGNA---VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 1889 GAHCERCQAGFVSSRDDPSAPCVSCPC 1915
G CERC G+ + C C C
Sbjct: 154 GTQCERCAPGYFGNPQKFGGSCQPCSC 180
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 709 bits (1829), Expect = 0.0
Identities = 534/1730 (30%), Positives = 823/1730 (47%), Gaps = 164/1730 (9%)
Query: 2006 CAPGFYGN--ALLPGNCTRCDCTPCGTEACDPHSGHCL-CKAGVTGRRCDRCQEGHFGFD 2062
C+PG+Y + L G C C+C + C SG C+ C+ G C+RCQEG++G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ-CQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
Query: 2063 GCGGCRPCAC---GPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRR 2116
G CR C C A G + +C C+ G G QC CAPGY+G P++ C+
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
Query: 2117 CQCPG----GRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVV 2172
C C G C P TG C +Q P P C+ CD CV+
Sbjct: 178 CSCNSNGQLGSCHPLTGDCI----------------NQEPKDSSPAEE---CDDCDSCVM 218
Query: 2173 LLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQ 2232
LL+DL G L + QL+G++AS+ ++ + DL++QL + +
Sbjct: 219 TLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSK 278
Query: 2233 LEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSEL 2292
+E LE++ T L Q T + +Q+ + TL +
Sbjct: 279 IEGLERELTDLN--------QEFETLQEKAQVNSRKAQTLNNN----------------- 313
Query: 2293 MSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARV 2352
N + S ++L + V R + +L R+
Sbjct: 314 ---------VNRATQSAKELDVKIKNVIRNV-----------------------HMLNRI 341
Query: 2353 QEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEA 2412
+ + EN LA RD L ++EA L DLR L A ++A LN N+ L
Sbjct: 342 RTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAI 401
Query: 2413 LQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRM 2472
++ +E++ + L A +L L ++++++E E+LAASL+ AR L ++
Sbjct: 402 QRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKV 461
Query: 2473 QTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAV 2532
+ S + K LVE AE HA+ L +LA L I + + D L + A++A+ AY IL A+
Sbjct: 462 RELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAI 521
Query: 2533 QAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQ 2591
+AAEDAA +A ++ TV+++ L +A+ L +NS L EA + +++ V AL
Sbjct: 522 KAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALN 581
Query: 2592 GARTQLRDVRAKKDQLEAHIQAAQ-AMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQL 2650
+ L V +K+ ++ ++ + + + + I+ AK++ +A D V L
Sbjct: 582 NLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGL 641
Query: 2651 QAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASL 2710
+Q +VER + Y + +D +A+ DA +SV+ L LP L K+ + + + +
Sbjct: 642 NPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGN- 700
Query: 2711 ALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPE 2770
+S ++ R+RELI QAR AASKV VPM+FNG+SGV++R P DL DL YT+L +LQ P
Sbjct: 701 -ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPN 759
Query: 2771 PEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQ--- 2827
GTE+ FVMY+G++ A+ DY+G+++ D ++ VY LG+ A L +D+ + +
Sbjct: 760 SRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR-EAELQVDQILTKSETK 818
Query: 2828 ---FAAVSLDRTLQFGHMSVTVERQMIQ-ETKG--DTVAPGAEGLLNLRPDDFVFYVGGY 2881
V R QF ++ T + ET G D + LLNL P++ VFYVGGY
Sbjct: 819 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 878
Query: 2882 PSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLT 2941
P F P L FP Y+GCIE+D LNE V+SLYNF++TF L+T PC R K +
Sbjct: 879 PPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE-----S 933
Query: 2942 DGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLL 3001
D +Y +GTG+AR+ + F Q ++ G+LFF + +F+ L +++G L++
Sbjct: 934 DKNYFEGTGYARVPTQPH-APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVR 992
Query: 3002 YDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELAD 3061
Y + L K + +IQ+ +G +KR+ + V+ V + D ++
Sbjct: 993 YKLNSELPKERGVGDAIN-NGRDHSIQI-KIGKLQKRMWINVD---VQNTIIDGEVFDFS 1047
Query: 3062 AYYLGGVPPDQLPPSLRRLFP-TGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL 3120
YYLGG+ P ++R F + + RGC+K +K V L +T GV+ C+ D
Sbjct: 1048 TYYLGGI-----PIAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVGVTKKCSEDWK 1100
Query: 3121 VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR 3180
+ R+ +F G L + P T ++ + FGF + Q S +L + QV+L+ G
Sbjct: 1101 LVRSASFSRGGQLSFTDLGLPP-TDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGY 1159
Query: 3181 VSLQLLRTE---VKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQ 3237
+ L + K+ + DG HYV+ S+ +G+ L +DDQL + L+
Sbjct: 1160 IELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS------KRLKHI 1213
Query: 3238 PEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST-GCA--- 3293
L LGG NF GCISNVFVQRL V DL N +VS GC+
Sbjct: 1214 SSSRQSLRLGG-------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNK 1266
Query: 3294 PALQAQTPGLGPRGLQATARKASRRSRQPARHP--------ACMLPPHLRTTRDSYQFGG 3345
P G T R P P AC P + + QFG
Sbjct: 1267 PPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGD 1326
Query: 3346 SLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQM 3405
+SHL F + ++ + SSRGL+ T + +AL+LS G V +
Sbjct: 1327 IPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG---TKNSFMALYLSKGRLVFAL 1383
Query: 3406 EGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPH 3465
G +LR +S+++ G+WH V + + LV DG RA +EG + P
Sbjct: 1384 GTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRA--REGSLPGNSTISIRAPV 1441
Query: 3466 TLFVGGLPASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFP 3525
L G P S LP T F GC+K +L +PL P+ GV+ C+ GPLE G++F
Sbjct: 1442 YL---GSPPSGKPKSLP-TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFS 1497
Query: 3526 GSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADD 3585
GG + L P+ L +RP ++TG++ H+G ++ +L + + +V D
Sbjct: 1498 EEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG-SQPGKHLCVYLEAGKVTASMDS 1556
Query: 3586 GAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYL 3645
GAG STSVT LCDGQWH +AV ++L LE+D S++T G + A PL+L
Sbjct: 1557 GAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHL 1616
Query: 3646 GGLPEPMAVQPWP--PAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCP 3693
GG P + P ++ GC+R + VN PV +T ++EV G V +GCP
Sbjct: 1617 GGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1666
Score = 198 bits (503), Expect = 9e-50
Identities = 85/149 (57%), Positives = 102/149 (68%), Gaps = 9/149 (6%)
Query: 1843 QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSS 1902
Q C+PG+YRD KGL+ GRCVPC C+GHS++C GSG+CV+CQHNT G HCERCQ G+ +
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 1903 RDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVL 1962
S C +CPCP +N+FA GCV+ GG +C CK GY G CERCAPG+FGNP
Sbjct: 117 AVHGS--CRACPCP---HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 171
Query: 1963 GSSCQPCDCSGNGDPNLLFSDCDPLTGAC 1991
G SCQPC C+ NG C PLTG C
Sbjct: 172 GGSCQPCSCNSNGQ----LGSCHPLTGDC 196
Score = 98.2 bits (243), Expect = 1e-19
Identities = 57/162 (35%), Positives = 79/162 (48%), Gaps = 27/162 (16%)
Query: 574 CAPGYF------HFPLCQLCGCSPAGTLPEGCDEAGRCL-CQPEFAGPHCDRCRPGYHG- 625
C+PGY+ + C C C+ G + D +G C+ CQ AG HC+RC+ GY+G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 626 --FPNCQACTCDPRGALDQLCGAGG---LCRCRPGYTGTACQECSPGFHGFP-----SCV 675
+C+AC C + C G C C+ GYTGT C+ C+PG+ G P SC
Sbjct: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
Query: 676 PCHCSAEGSLHAACDPRSGQC------SCRPRVTGLRCDTCV 711
PC C++ G L +C P +G C P CD+CV
Sbjct: 177 PCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDCDSCV 217
Score = 82.8 bits (203), Expect = 6e-15
Identities = 54/174 (31%), Positives = 72/174 (41%), Gaps = 29/174 (16%)
Query: 408 CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFT 466
C PG+YR +H C CNC C+D +G C C+ N +GE C+ C EG+
Sbjct: 59 CSPGYYR--DHKGLYTGRCVPCNCNGH--SNQCQDGSGICVNCQHNTAGEHCERCQEGYY 114
Query: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC 526
G N G C C + C + RC CK + GT C
Sbjct: 115 G-----------NAVH------GSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC 157
Query: 527 ELCAPGF------YGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRC 574
E CAPG+ +G CQPC C+S G C P TG C + + + + C
Sbjct: 158 ERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEEC 210
Score = 81.6 bits (200), Expect = 1e-14
Identities = 46/152 (30%), Positives = 66/152 (43%), Gaps = 35/152 (23%)
Query: 336 CCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCID 395
C PG+ ++ C CNC GH+ C G G+C++
Sbjct: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
Query: 396 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTG---RCYCRPN 452
CQH+T G +CERC G+Y + H CR C C + T + G RC C+
Sbjct: 97 CQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 151
Query: 453 FSGERCDVCAEGFTGFP-----SCYPTPSSSN 479
++G +C+ CA G+ G P SC P +SN
Sbjct: 152 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN 183
Score = 80.1 bits (196), Expect = 4e-14
Identities = 51/149 (34%), Positives = 68/149 (45%), Gaps = 20/149 (13%)
Query: 486 LPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG----CQP 540
L G+ V C+C+ N C+ G C+ C+ N G HCE C G+YG C+
Sbjct: 70 LYTGRCVPCNCNG---HSNQCQDGS--GICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA 124
Query: 541 CQCSSPGVADDRCDPDTG--QCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAG 593
C C C + G +C C+ G+ G C+RCAPGYF P CQ C C+ G
Sbjct: 125 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG 184
Query: 594 TLPEGCDEAGRCLCQ-PEFAGP--HCDRC 619
L G C+ Q P+ + P CD C
Sbjct: 185 QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 79.3 bits (194), Expect = 6e-14
Identities = 53/170 (31%), Positives = 71/170 (41%), Gaps = 35/170 (20%)
Query: 298 GRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN 354
GRCV C+GH++ C D + CQHNT G C+RC G+ + A S
Sbjct: 73 GRCVPCNCNGHSNQCQ-----DGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCR 123
Query: 355 ECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR 414
C + AT C GG V C+ TG CERC PG++
Sbjct: 124 ACPCPHTNSFATGC-----------------VVNGGDVRCSCKAGYTGTQCERCAPGYFG 166
Query: 415 SPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY---CRPNFSGERCDVC 461
+P S C+ C+C S+ G+C LTG C + + E CD C
Sbjct: 167 NPQKFGGS---CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 78.2 bits (191), Expect = 1e-13
Identities = 48/162 (29%), Positives = 63/162 (38%), Gaps = 16/162 (9%)
Query: 662 QECSPGFHGFPS------CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGA 714
Q CSPG++ CVPC+C+ + C SG C +C+ G C+ C G
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSN---QCQDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 715 YNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPE 771
Y C A C + V C C+A G C+RC PG++G
Sbjct: 114 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 173
Query: 772 GCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKD 813
C CSC+ G LG C P TG C + C D
Sbjct: 174 SCQPCSCNSNGQLG---SCHPLTGDCINQEPKDSSPAEECDD 212
Score = 77.8 bits (190), Expect = 2e-13
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 1448 PTCEPFGGQCPCHAHVIGRDCSRCATGYWG------FPNCRPCDCG--ARLCDELTGQCI 1499
P +P G ++V R C+ GY+ C PC+C + C + +G C+
Sbjct: 36 PFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICV 95
Query: 1500 -CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG--QCKCRPNV 1556
C T C CQ +G C C C P C + G +C C+
Sbjct: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPC--PHTNSFATG-CVVNGGDVRCSCKAGY 152
Query: 1557 TGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPGVCDPLTGQCY---CKENVQGPKCD 1608
TG +C+ C+PG+ G P+ C+PC C+ G G C PLTG C K++ +CD
Sbjct: 153 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECD 211
Query: 1609 QC 1610
C
Sbjct: 212 DC 213
Score = 69.3 bits (168), Expect = 7e-11
Identities = 46/158 (29%), Positives = 62/158 (39%), Gaps = 9/158 (5%)
Query: 710 CVPGAY-NFPYCEAGSCHPAGLAPVDPALPEAQVPCM-CRAHVEGPSCDRCKPGFWGLSP 767
C PG Y + G C P + C+ C+ + G C+RC+ G++G +
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
Query: 768 SNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCR 827
C C C + G +C CK G C C G+FG Q C+
Sbjct: 119 HG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
Query: 828 SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
C C+ G LG SC P TG C Q P S PA +
Sbjct: 177 PCSCNSNGQLG-SCHPLTGDC----INQEPKDSSPAEE 209
Score = 61.2 bits (147), Expect = 2e-08
Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 1525 CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHG---YPRCRPCDCH 1580
C CNC+G Q C SG C C+ N G C+ C G++G + CR C C
Sbjct: 75 CVPCNCNGHSNQ------CQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
Query: 1581 EAGTAPGVCDPLTG--QCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
+ C G +C CK G +C++C+ G F C C C
Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
Score = 53.5 bits (127), Expect = 4e-06
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 11/79 (13%)
Query: 1432 NNGARPCGCHEVGATGPTCEPFGG--QCPCHAHVIGRDCSRCATGYWGFP-----NCRPC 1484
+ R C C + C GG +C C A G C RCA GY+G P +C+PC
Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
Query: 1485 DCGAR----LCDELTGQCI 1499
C + C LTG CI
Sbjct: 179 SCNSNGQLGSCHPLTGDCI 197
Score = 49.7 bits (117), Expect = 5e-05
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC--HGHSDRCLPGSGVCVDCQHNTE 1888
C C A Y G C+ CAPG++ + + F G C PC C +G C P +G C++ Q +
Sbjct: 146 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCIN-QEPKD 203
Query: 1889 GAHCERC 1895
+ E C
Sbjct: 204 SSPAEEC 210
Score = 43.1 bits (100), Expect = 0.005
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 7/87 (8%)
Query: 1833 CPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC---HGHSDRCLPGSG-VCVDCQHNTE 1888
C + G+ C+ C G+Y + G C C C + + C+ G V C+
Sbjct: 97 CQHNTAGEHCERCQEGYYGNA---VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 1889 GAHCERCQAGFVSSRDDPSAPCVSCPC 1915
G CERC G+ + C C C
Sbjct: 154 GTQCERCAPGYFGNPQKFGGSCQPCSC 180
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 677 bits (1746), Expect = 0.0
Identities = 514/1834 (28%), Positives = 863/1834 (47%), Gaps = 158/1834 (8%)
Query: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
+ E+C GFF L C PCDC+GN + +C +G C C R+TTG CE C
Sbjct: 63 AAEKCNAGFFHT---LSGECVPCDCNGNSN------ECLDGSGYCVHCQRNTTGEHCEKC 113
Query: 2007 APGFYGNAL--LPGNCTRCDCT----PCGTEACDPHSG--HCLCKAGVTGRRCDRCQEGH 2058
G+ G+++ P C C C E+C +G C+C G C+RC G+
Sbjct: 114 LDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
Query: 2059 FGFDGCGG--CRPCACGPAAEGS----ECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE 2111
+G G C+ C C ++ + +C +GQC +C T G +C CAPGY+G
Sbjct: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 2112 --QGCRRCQCPGGRCDPHTGRCNC----PPGLSGERCDTCSQQHQVPVPGGPVGHSIHCE 2165
+ C C C GG CD TG C PP +G C T S
Sbjct: 234 IAKNCAVCNCGGGPCDSVTGECLEEGFEPP--TGMDCPTIS------------------- 272
Query: 2166 VCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGP 2225
CD CV L D L A + + +++ + A ++ +NA+I L+++L
Sbjct: 273 -CDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQ 331
Query: 2226 RHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQL--LAGTEA--TLGHAKTLLAA 2281
Q+ E SL D L V +QAS+ L E+ T+ HA L+
Sbjct: 332 YALRKIQINNAENTMKSLLSDVEEL----VEKENQASRKGQLVQKESMDTINHASQLVEQ 387
Query: 2282 IRAVDRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARD-LGAPQAAAEA 2340
+ + E+ ++ + G + +P +++ L +++L E+R+R + +
Sbjct: 388 AHDMRDKIQEINNKMLYYGEEHELSP--KEISEKLVLAQKMLEEIRSRQPFFTQRELVDE 445
Query: 2341 ELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQE 2400
E A LL++ E L E + L ++L + A L DL+EAL++A++ R+A++
Sbjct: 446 EADEAYELLSQA-ESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAED 504
Query: 2401 LNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAAS 2460
+N R + ++++ + + +L + D+L + L LD + + A
Sbjct: 505 MNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAE 564
Query: 2461 LDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIE 2520
+DGA++ L ++ S L V+ A HAQ L Q A LS + + + L Q+A++
Sbjct: 565 IDGAKSELQVKLSNLSNLSHDL--VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALD 622
Query: 2521 ASNAYSRILQAVQAAEDAAGQALQQADHTWATVV------------RQGLVDRAQQLLAN 2568
ASN Y I+ V A + A AL D + V + L+++A++L A
Sbjct: 623 ASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAK 682
Query: 2569 S-TALEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSK 2627
+ ++ +EA+ +R+G A +T+L D A + + A + + +
Sbjct: 683 AESSSDEAVADTSRRVGGALARKSALKTRLSD-------------AVKQLQAAERGDAQQ 729
Query: 2628 KIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLE 2687
++ ++ + EA T VQ M N+ W + AV A +V L
Sbjct: 730 RLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLT 789
Query: 2688 KTLPQLLAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQL 2747
+ +PQLL +L +E + + +SASI R+RELIAQ R ASK++V M F+G+S V++
Sbjct: 790 EVVPQLLDQLRTVEQK---RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 846
Query: 2748 RTPRDLADLAAYTALKFYLQGPEPEPG-QGTEDRFVMYMGSRQATGDYMGVSLRDKKVHW 2806
+ + DL A+T+L Y++ P P T D+F++Y+GS+ A +YMG+++++ + +
Sbjct: 847 HSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVY 906
Query: 2807 VYQLGEAGPAVLSIDEDIGE---QFAAVSLDRTLQFGHMSVTV-------ERQMIQETKG 2856
VY LG + + + F+ V ++R + G + +TV E + I+ KG
Sbjct: 907 VYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIK--KG 964
Query: 2857 DTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFE 2916
+ G + LL+L P+D VFYVGG PS F P L PG+ GC+E+ TLN +V+SLYNF+
Sbjct: 965 EF--SGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFK 1022
Query: 2917 RTFQLDTAVDRPCARSKSTGDPWLTDGSYLDGTGFA---RISFDSQISTTKRFEQELRLV 2973
+ +D + PCAR K + DG+G+A I+ + RF+ E+R
Sbjct: 1023 HIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTP 1082
Query: 2974 SYSGVLFFLKQQSQFLCLAVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSA----SKAIQV 3029
+ +G++ + S F L ++ G L + YDFG P+ L A +K ++
Sbjct: 1083 ADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGF---SGGPVHLEDTLKKAQINDAKYHEI 1139
Query: 3030 FLLGGSRKRVLVRVERATVYSVEQDNDLELADAYYLGGVPPDQLPP-SLRRLFPTGGSVR 3088
++ + K++++ V+R V S++ + Y+GG PP+ L +LR P + R
Sbjct: 1140 SIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFR 1199
Query: 3089 GCVKGIKALGKYVD-LKRLNTTGVSAGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNV 3147
GC+KG + K + L++ T GV GC D L+ R F+G F+ ++ ++ G
Sbjct: 1200 GCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFI-ASIQKISFFDG-F 1257
Query: 3148 YSGFGFHSAQDSALLYYRASPDGLCQVSLQQGRVSLQLLRTEVKT-QAGFADGAPHYVAF 3206
GF F + Q + LL+Y AS + +SL G V + + +V++ + DG H+V
Sbjct: 1258 EGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVIS 1317
Query: 3207 YSNATGVWLYVD-DQLQQMKPHRGPPPELQPQPEGPPRLLLGGLPESGTIYNFSGCISNV 3265
+ T L VD ++ P +G + Q + + GG P S NF+GCISN
Sbjct: 1318 SVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEK---KFYFGGSPISAQYANFTGCISNA 1374
Query: 3266 FVQRLLGPQRVFDLQQNLGSVNVSTGCAPALQAQTPGLGPRGLQATARKASRRSR----- 3320
+ R+ V D Q+ V+ S P + L +G + KAS+ +
Sbjct: 1375 YFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSK 1434
Query: 3321 -QPARHPACMLPPHLRTTRDS--------------YQFGGSLSSHLEFVGILARHRNWPS 3365
P+ P + P T R+S YQ+GG+ +S EF +
Sbjct: 1435 DAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQ 1494
Query: 3366 LSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRW 3425
S+ + RSS G++ + + + + + LFL++G V +L+ +S+++ G W
Sbjct: 1495 FSIRLRTRSSHGMIFYVSD-QEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLW 1553
Query: 3426 HKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSKLPVT- 3484
H V E++ LV DG R + P + A +++GG+ + +
Sbjct: 1554 HDVIFIRERSSGRLVIDGLRVLEESLPPTE---ATWKIKGPIYLGGVAPGKAVKNVQINS 1610
Query: 3485 -VGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDV 3543
FSGC+ L+L+G + + ++ VTPC GP+E G +F GG + LD
Sbjct: 1611 IYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKF 1670
Query: 3544 GLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVLCDG 3603
+ EVRP + +G + H G + YL + + QV+++ ++G +FSTSVT LCDG
Sbjct: 1671 EIAFEVRPRSSSGTLVH-GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDG 1729
Query: 3604 QWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA--Y 3661
+WHR+ V++ NV++L+VD++ NH VGPL P+++GG+PE + P+ +
Sbjct: 1730 RWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPF 1789
Query: 3662 CGCMRRLAVNRSPVAMTRSVEVHGAVGASGCPAA 3695
GC+R ++ PV+ +++ V GAV + CPAA
Sbjct: 1790 TGCIRHFVIDGHPVSFSKAALVSGAVSINSCPAA 1823
Score = 237 bits (605), Expect = 1e-61
Identities = 105/203 (51%), Positives = 136/203 (66%), Gaps = 11/203 (5%)
Query: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900
+ ++C GF+ + G CVPC C+G+S+ CL GSG CV CQ NT G HCE+C G++
Sbjct: 63 AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
Query: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958
S R P C CPCPL +N FAE C + G +C+C YAG +CERCAPG++GN
Sbjct: 119 GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018
PL++GS+C+ CDCSGN DPNL+F DCD +TG CR CLR+TTG +CE CAPG+YG+A +
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 2019 NCTRCDCTPCGTEACDPHSGHCL 2041
NC C+ CG CD +G CL
Sbjct: 237 NCAVCN---CGGGPCDSVTGECL 256
Score = 100 bits (249), Expect = 3e-20
Identities = 71/238 (29%), Positives = 98/238 (41%), Gaps = 53/238 (22%)
Query: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412
+ EC C+C G++ +C LDG+ G C+ CQ +TTG +CE+CL G+
Sbjct: 76 SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117
Query: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466
+P C+ C C ++F + +C G RC C N++G C+ CA G+
Sbjct: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524
G P +L CDCS D G+C C N G
Sbjct: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
Query: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT--------CDRC 574
CE CAPG+YG C+ CD TG+C GFE T CD+C
Sbjct: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGMDCPTISCDKC 276
Score = 99.8 bits (247), Expect = 5e-20
Identities = 74/245 (30%), Positives = 100/245 (40%), Gaps = 46/245 (18%)
Query: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553
SA G Q +PRV P E C GF+ C PC C+ + C
Sbjct: 40 SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91
Query: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601
+G C C+ G C++C GY + CQ C C E C +
Sbjct: 92 LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651
A RC+C +AGP+C+RC PGY+G P C+ C C DP + G CR
Sbjct: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
Query: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQC---SCRPRVTG 704
C TG C+ C+PG++G +C C+C CD +G+C P TG
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEP-PTG 265
Query: 705 LRCDT 709
+ C T
Sbjct: 266 MDCPT 270
Score = 98.6 bits (244), Expect = 1e-19
Identities = 66/205 (32%), Positives = 90/205 (43%), Gaps = 40/205 (19%)
Query: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487
PC C+ C G C C + G C +C GY G P C+PC C
Sbjct: 81 PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538
A C G +CIC P+C C P +G L+G C++C+CSG L
Sbjct: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
Query: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593
CD +GQC+ C N TG +C+ C+PG++G R C C+C G CD +T
Sbjct: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252
Query: 1594 GQCYCKENVQGP--------KCDQC 1610
G+C +E + P CD+C
Sbjct: 253 GEC-LEEGFEPPTGMDCPTISCDKC 276
Score = 83.2 bits (204), Expect = 4e-15
Identities = 59/202 (29%), Positives = 82/202 (40%), Gaps = 22/202 (10%)
Query: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716
A ++C+ GF S CVPC C+ + C SG C C+ TG C+ C+ G
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768
+C+ C LA + V C+C + GP+C+RC PG++G
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826
C +C C + E C TGQC C + G C C G++G D C
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 827 RSCRCDIGGALGQSCEPRTGVC 848
C C G C+ TG C
Sbjct: 239 AVCNCG-----GGPCDSVTGEC 255
Score = 83.2 bits (204), Expect = 4e-15
Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%)
Query: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533
C PCDC C + +G C+ C T C C G + G C+ C C P
Sbjct: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137
Query: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586
+ + +C +G +C C N G C+ C+PG++G P C+ CDC + P
Sbjct: 138 HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195
Query: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
+ CD +TGQC C N G KC++C+ G + DA K C C C G
Sbjct: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
Score = 75.9 bits (185), Expect = 7e-13
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 46/188 (24%)
Query: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
++ G CV C+G+++ C D CQ NT G C++C G+ +
Sbjct: 74 TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124
Query: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406
+ CQ C C A CY + G V C + G NCE
Sbjct: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167
Query: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459
RC PG+Y +PL C++C+C + F D C+++TG+C C N +G +C+
Sbjct: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222
Query: 460 VCAEGFTG 467
CA G+ G
Sbjct: 223 RCAPGYYG 230
Score = 68.9 bits (167), Expect = 9e-11
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 29/142 (20%)
Query: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365
A++C K+ ++C C N G C+RC PG+ P + C+ C+C G++
Sbjct: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193
Query: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
DP + + + G C +C +TTG CERC PG+Y +
Sbjct: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237
Query: 426 CRRCNCESDFTDGTCEDLTGRC 447
C CNC G C+ +TG C
Sbjct: 238 CAVCNCGG----GPCDSVTGEC 255
Score = 65.9 bits (159), Expect = 7e-10
Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%)
Query: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562
+PP C F H L G C C+C+G + C SG C C+ N TG C+
Sbjct: 60 LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111
Query: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611
C G+ G P+ C+PC C H A A C G +C C EN GP C++C+
Sbjct: 112 KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170
Query: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635
G + C +C C G ++
Sbjct: 171 PGYYGNPLLIGSTCKKCDCSGNSD 194
Score = 62.8 bits (151), Expect = 6e-09
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883
C+C +Y G +C+ CAPG+Y + L +G C C C G+SD C +G C +C
Sbjct: 155 CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
Query: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915
NT G CERC G+ + C C C
Sbjct: 213 LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243
Score = 59.3 bits (142), Expect = 7e-08
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765
C G N FP+ GS + + DP PE P + + P+ ++C GF+
Sbjct: 21 CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74
Query: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822
C C C+ G EC G+G C C+ + G+ C C DG+ G + A
Sbjct: 75 LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867
F C+ C C + +SC + G C C N GP C A +Y
Sbjct: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Score = 54.7 bits (130), Expect = 2e-06
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 27/122 (22%)
Query: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478
L + + C C G + P C+ GQC C + G C RCA GY+G
Sbjct: 178 LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538
NC C+CG CD +TG+C+ PP + C P + C++C + +L
Sbjct: 236 KNCAVCNCGGGPCDSVTGECL-EEGFEPPTGMDC--------PTISCDKC------VWDL 280
Query: 1539 TD 1540
TD
Sbjct: 281 TD 282
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 673 bits (1737), Expect = 0.0
Identities = 510/1830 (27%), Positives = 859/1830 (46%), Gaps = 157/1830 (8%)
Query: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
+ E+C GFF L C PCDC+GN + +C +G C C R+TTG CE C
Sbjct: 63 AAEKCNAGFFHT---LSGECVPCDCNGNSN------ECLDGSGYCVHCQRNTTGEHCEKC 113
Query: 2007 APGFYGNAL--LPGNCTRCDCT----PCGTEACDPHSG--HCLCKAGVTGRRCDRCQEGH 2058
G+ G+++ P C C C E+C +G C+C G C+RC G+
Sbjct: 114 LDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
Query: 2059 FGFDGCGG--CRPCACGPAAEGS----ECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE 2111
+G G C+ C C ++ + +C +GQC +C T G +C CAPGY+G
Sbjct: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 2112 --QGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDH 2169
+ C C C GG CD TG C + P G CD
Sbjct: 234 IAKNCAVCNCGGGPCDSVTGEC---------------LEEGFEPPTG----------CDK 268
Query: 2170 CVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHET 2229
CV L D L A + + +++ + A ++ +NA+I L+++L
Sbjct: 269 CVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALR 328
Query: 2230 AQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQL--LAGTEA--TLGHAKTLLAAIRAV 2285
Q+ E SL D L V +QAS+ L E+ T+ HA L+ +
Sbjct: 329 KIQINNAENTMKSLLSDVEEL----VEKENQASRKGQLVQKESMDTINHASQLVEQAHDM 384
Query: 2286 DRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAA 2344
+ E+ ++ + G + +P +++ L +++L E+R+R + + E
Sbjct: 385 RDKIQEINNKMLYYGEEHELSP--KEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADE 442
Query: 2345 AQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSR 2404
A LL++ E L E + L ++L + A L DL+EAL++A++ R+A+++N
Sbjct: 443 AYELLSQA-ESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRA 501
Query: 2405 NQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGA 2464
R + ++++ + + +L + D+L + L LD + + A +DGA
Sbjct: 502 TAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
Query: 2465 RTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNA 2524
++ L ++ S L V+ A HAQ L Q A LS + + + L Q+A++ASN
Sbjct: 562 KSELQVKLSNLSNLSHDL--VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNV 619
Query: 2525 YSRILQAVQAAEDAAGQALQQADHTWATVV------------RQGLVDRAQQLLANS-TA 2571
Y I+ V A + A AL D + V + L+++A++L A + ++
Sbjct: 620 YENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESS 679
Query: 2572 LEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAH 2631
+EA+ +R+G A +T+L D A + + A + + +++
Sbjct: 680 SDEAVADTSRRVGGALARKSALKTRLSD-------------AVKQLQAAERGDAQQRLGQ 726
Query: 2632 AKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLP 2691
++ + EA T VQ M N+ W + AV A +V L + +P
Sbjct: 727 SRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVP 786
Query: 2692 QLLAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPR 2751
QLL +L +E + + +SASI R+RELIAQ R ASK++V M F+G+S V++ +
Sbjct: 787 QLLDQLRTVEQK---RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRT 843
Query: 2752 DLADLAAYTALKFYLQGPEPEPG-QGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQL 2810
+ DL A+T+L Y++ P P T D+F++Y+GS+ A +YMG+++++ + +VY L
Sbjct: 844 SMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNL 903
Query: 2811 GEAGPAVLSIDEDIGE---QFAAVSLDRTLQFGHMSVTV-------ERQMIQETKGDTVA 2860
G + + + F+ V ++R + G + +TV E + I+ KG+
Sbjct: 904 GTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIK--KGEF-- 959
Query: 2861 PGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQ 2920
G + LL+L P+D VFYVGG PS F P L PG+ GC+E+ TLN +V+SLYNF+ +
Sbjct: 960 SGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYN 1019
Query: 2921 LDTAVDRPCARSKSTGDPWLTDGSYLDGTGFA---RISFDSQISTTKRFEQELRLVSYSG 2977
+D + PCAR K + DG+G+A I+ + RF+ E+R + +G
Sbjct: 1020 MDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNG 1079
Query: 2978 VLFFLKQQSQFLCLAVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSA----SKAIQVFLLG 3033
++ + S F L ++ G L + YDFG P+ L A +K ++ ++
Sbjct: 1080 LILLMVNGSMFFRLEMRNGYLHVFYDFGF---SGGPVHLEDTLKKAQINDAKYHEISIIY 1136
Query: 3034 GSRKRVLVRVERATVYSVEQDNDLELADAYYLGGVPPDQLPP-SLRRLFPTGGSVRGCVK 3092
+ K++++ V+R V S++ + Y+GG PP+ L +LR P + RGC+K
Sbjct: 1137 HNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
Query: 3093 GIKALGKYVD-LKRLNTTGVSAGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGF 3151
G + K + L++ T GV GC D L+ R F+G F+ ++ ++ G GF
Sbjct: 1197 GFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFI-ASIQKISFFDG-FEGGF 1254
Query: 3152 GFHSAQDSALLYYRASPDGLCQVSLQQGRVSLQLLRTEVKT-QAGFADGAPHYVAFYSNA 3210
F + Q + LL+Y AS + +SL G V + + +V++ + DG H+V +
Sbjct: 1255 NFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSP 1314
Query: 3211 TGVWLYVD-DQLQQMKPHRGPPPELQPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQR 3269
T L VD ++ P +G + Q + + GG P S NF+GCISN + R
Sbjct: 1315 TRYELIVDKSRVGSKNPTKGKIEQTQASEK---KFYFGGSPISAQYANFTGCISNAYFTR 1371
Query: 3270 LLGPQRVFDLQQNLGSVNVSTGCAPALQAQTPGLGPRGLQATARKASRRSR------QPA 3323
+ V D Q+ V+ S P + L +G + KAS+ + P+
Sbjct: 1372 VDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPS 1431
Query: 3324 RHPACMLPPHLRTTRDS--------------YQFGGSLSSHLEFVGILARHRNWPSLSMH 3369
P + P T R+S YQ+GG+ +S EF + S+
Sbjct: 1432 WDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIR 1491
Query: 3370 VLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVS 3429
+ RSS G++ + + + + + LFL++G V +L+ +S+++ G WH V
Sbjct: 1492 LRTRSSHGMIFYVSD-QEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVI 1550
Query: 3430 VRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSKLPVT--VGF 3487
E++ LV DG R + P + A +++GG+ + + F
Sbjct: 1551 FIRERSSGRLVIDGLRVLEESLPPTE---ATWKIKGPIYLGGVAPGKAVKNVQINSIYSF 1607
Query: 3488 SGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLEL 3547
SGC+ L+L+G + + ++ VTPC GP+E G +F GG + LD +
Sbjct: 1608 SGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAF 1667
Query: 3548 EVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHR 3607
EVRP + +G + H G + YL + + QV+++ ++G +FSTSVT LCDG+WHR
Sbjct: 1668 EVRPRSSSGTLVH-GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHR 1726
Query: 3608 LAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA--YCGCM 3665
+ V++ NV++L+VD++ NH VGPL P+++GG+PE + P+ + GC+
Sbjct: 1727 ITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCI 1786
Query: 3666 RRLAVNRSPVAMTRSVEVHGAVGASGCPAA 3695
R ++ PV+ +++ V GAV + CPAA
Sbjct: 1787 RHFVIDGHPVSFSKAALVSGAVSINSCPAA 1816
Score = 242 bits (617), Expect = 6e-63
Identities = 108/216 (50%), Positives = 141/216 (65%), Gaps = 11/216 (5%)
Query: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900
+ ++C GF+ + G CVPC C+G+S+ CL GSG CV CQ NT G HCE+C G++
Sbjct: 63 AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
Query: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958
S R P C CPCPL +N FAE C + G +C+C YAG +CERCAPG++GN
Sbjct: 119 GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018
PL++GS+C+ CDCSGN DPNL+F DCD +TG CR CLR+TTG +CE CAPG+YG+A +
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 2019 NCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRC 2054
NC C+ CG CD +G CL + CD+C
Sbjct: 237 NCAVCN---CGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 103 bits (256), Expect = 4e-21
Identities = 71/231 (30%), Positives = 98/231 (42%), Gaps = 46/231 (19%)
Query: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412
+ EC C+C G++ +C LDG+ G C+ CQ +TTG +CE+CL G+
Sbjct: 76 SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117
Query: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466
+P C+ C C ++F + +C G RC C N++G C+ CA G+
Sbjct: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524
G P +L CDCS D G+C C N G
Sbjct: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
Query: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT-CDRC 574
CE CAPG+YG C+ CD TG+C GFE T CD+C
Sbjct: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGCDKC 269
Score = 102 bits (254), Expect = 7e-21
Identities = 73/244 (29%), Positives = 98/244 (40%), Gaps = 42/244 (17%)
Query: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553
SA G Q +PRV P E C GF+ C PC C+ + C
Sbjct: 40 SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91
Query: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601
+G C C+ G C++C GY + CQ C C E C +
Sbjct: 92 LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651
A RC+C +AGP+C+RC PGY+G P C+ C C DP + G CR
Sbjct: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
Query: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
C TG C+ C+PG++G +C C+C CD +G+C C
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGC 266
Query: 708 DTCV 711
D CV
Sbjct: 267 DKCV 270
Score = 100 bits (250), Expect = 2e-20
Identities = 66/198 (33%), Positives = 90/198 (45%), Gaps = 33/198 (16%)
Query: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487
PC C+ C G C C + G C +C GY G P C+PC C
Sbjct: 81 PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538
A C G +CIC P+C C P +G L+G C++C+CSG L
Sbjct: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
Query: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593
CD +GQC+ C N TG +C+ C+PG++G R C C+C G CD +T
Sbjct: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252
Query: 1594 GQCYCKENVQGPK-CDQC 1610
G+C +E + P CD+C
Sbjct: 253 GEC-LEEGFEPPTGCDKC 269
Score = 84.3 bits (207), Expect = 2e-15
Identities = 61/211 (28%), Positives = 85/211 (40%), Gaps = 24/211 (11%)
Query: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716
A ++C+ GF S CVPC C+ + C SG C C+ TG C+ C+ G
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768
+C+ C LA + V C+C + GP+C+RC PG++G
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826
C +C C + E C TGQC C + G C C G++G D C
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 827 RSCRCD-------IGGALGQSCEPRTGVCRC 850
C C G L + EP TG +C
Sbjct: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 83.2 bits (204), Expect = 4e-15
Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%)
Query: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533
C PCDC C + +G C+ C T C C G + G C+ C C P
Sbjct: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137
Query: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586
+ + +C +G +C C N G C+ C+PG++G P C+ CDC + P
Sbjct: 138 HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195
Query: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
+ CD +TGQC C N G KC++C+ G + DA K C C C G
Sbjct: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
Score = 77.0 bits (188), Expect = 3e-13
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 69/250 (27%)
Query: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
++ G CV C+G+++ C D CQ NT G C++C G+ +
Sbjct: 74 TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124
Query: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406
+ CQ C C A CY + G V C + G NCE
Sbjct: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167
Query: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459
RC PG+Y +PL C++C+C + F D C+++TG+C C N +G +C+
Sbjct: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222
Query: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
CA G+ G D R + +C+ G C D G CL +
Sbjct: 223 RCAPGYYG------------DAR---------IAKNCAVCNCGGGPC--DSVTGECLEEG 259
Query: 520 NFQGTHCELC 529
T C+ C
Sbjct: 260 FEPPTGCDKC 269
Score = 70.5 bits (171), Expect = 3e-11
Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 29/161 (18%)
Query: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365
A++C K+ ++C C N G C+RC PG+ P + C+ C+C G++
Sbjct: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193
Query: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
DP + + + G C +C +TTG CERC PG+Y +
Sbjct: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237
Query: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFT 466
C CNC G C+ +TG C CD C T
Sbjct: 238 CAVCNCGG----GPCDSVTGECLEEGFEPPTGCDKCVWDLT 274
Score = 65.9 bits (159), Expect = 7e-10
Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%)
Query: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562
+PP C F H L G C C+C+G + C SG C C+ N TG C+
Sbjct: 60 LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111
Query: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611
C G+ G P+ C+PC C H A A C G +C C EN GP C++C+
Sbjct: 112 KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170
Query: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635
G + C +C C G ++
Sbjct: 171 PGYYGNPLLIGSTCKKCDCSGNSD 194
Score = 62.8 bits (151), Expect = 6e-09
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883
C+C +Y G +C+ CAPG+Y + L +G C C C G+SD C +G C +C
Sbjct: 155 CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
Query: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915
NT G CERC G+ + C C C
Sbjct: 213 LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243
Score = 59.3 bits (142), Expect = 7e-08
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765
C G N FP+ GS + + DP PE P + + P+ ++C GF+
Sbjct: 21 CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74
Query: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822
C C C+ G EC G+G C C+ + G+ C C DG+ G + A
Sbjct: 75 LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867
F C+ C C + +SC + G C C N GP C A +Y
Sbjct: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Score = 53.5 bits (127), Expect = 4e-06
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 34/122 (27%)
Query: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478
L + + C C G + P C+ GQC C + G C RCA GY+G
Sbjct: 178 LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538
NC C+CG CD +TG+C+ G P GC++C + +L
Sbjct: 236 KNCAVCNCGGGPCDSVTGECL----------------EEGFEPPTGCDKC------VWDL 273
Query: 1539 TD 1540
TD
Sbjct: 274 TD 275
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 673 bits (1737), Expect = 0.0
Identities = 510/1830 (27%), Positives = 859/1830 (46%), Gaps = 157/1830 (8%)
Query: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
+ E+C GFF L C PCDC+GN + +C +G C C R+TTG CE C
Sbjct: 63 AAEKCNAGFFHT---LSGECVPCDCNGNSN------ECLDGSGYCVHCQRNTTGEHCEKC 113
Query: 2007 APGFYGNAL--LPGNCTRCDCT----PCGTEACDPHSG--HCLCKAGVTGRRCDRCQEGH 2058
G+ G+++ P C C C E+C +G C+C G C+RC G+
Sbjct: 114 LDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
Query: 2059 FGFDGCGG--CRPCACGPAAEGS----ECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE 2111
+G G C+ C C ++ + +C +GQC +C T G +C CAPGY+G
Sbjct: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 2112 --QGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDH 2169
+ C C C GG CD TG C + P G CD
Sbjct: 234 IAKNCAVCNCGGGPCDSVTGEC---------------LEEGFEPPTG----------CDK 268
Query: 2170 CVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHET 2229
CV L D L A + + +++ + A ++ +NA+I L+++L
Sbjct: 269 CVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALR 328
Query: 2230 AQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQL--LAGTEA--TLGHAKTLLAAIRAV 2285
Q+ E SL D L V +QAS+ L E+ T+ HA L+ +
Sbjct: 329 KIQINNAENTMKSLLSDVEEL----VEKENQASRKGQLVQKESMDTINHASQLVEQAHDM 384
Query: 2286 DRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAA 2344
+ E+ ++ + G + +P +++ L +++L E+R+R + + E
Sbjct: 385 RDKIQEINNKMLYYGEEHELSP--KEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADE 442
Query: 2345 AQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSR 2404
A LL++ E L E + L ++L + A L DL+EAL++A++ R+A+++N
Sbjct: 443 AYELLSQA-ESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRA 501
Query: 2405 NQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGA 2464
R + ++++ + + +L + D+L + L LD + + A +DGA
Sbjct: 502 TAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
Query: 2465 RTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNA 2524
++ L ++ S L V+ A HAQ L Q A LS + + + L Q+A++ASN
Sbjct: 562 KSELQVKLSNLSNLSHDL--VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNV 619
Query: 2525 YSRILQAVQAAEDAAGQALQQADHTWATVV------------RQGLVDRAQQLLANS-TA 2571
Y I+ V A + A AL D + V + L+++A++L A + ++
Sbjct: 620 YENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESS 679
Query: 2572 LEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAH 2631
+EA+ +R+G A +T+L D A + + A + + +++
Sbjct: 680 SDEAVADTSRRVGGALARKSALKTRLSD-------------AVKQLQAAERGDAQQRLGQ 726
Query: 2632 AKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLP 2691
++ + EA T VQ M N+ W + AV A +V L + +P
Sbjct: 727 SRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVP 786
Query: 2692 QLLAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPR 2751
QLL +L +E + + +SASI R+RELIAQ R ASK++V M F+G+S V++ +
Sbjct: 787 QLLDQLRTVEQK---RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRT 843
Query: 2752 DLADLAAYTALKFYLQGPEPEPG-QGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQL 2810
+ DL A+T+L Y++ P P T D+F++Y+GS+ A +YMG+++++ + +VY L
Sbjct: 844 SMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNL 903
Query: 2811 GEAGPAVLSIDEDIGE---QFAAVSLDRTLQFGHMSVTV-------ERQMIQETKGDTVA 2860
G + + + F+ V ++R + G + +TV E + I+ KG+
Sbjct: 904 GTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIK--KGEF-- 959
Query: 2861 PGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQ 2920
G + LL+L P+D VFYVGG PS F P L PG+ GC+E+ TLN +V+SLYNF+ +
Sbjct: 960 SGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYN 1019
Query: 2921 LDTAVDRPCARSKSTGDPWLTDGSYLDGTGFA---RISFDSQISTTKRFEQELRLVSYSG 2977
+D + PCAR K + DG+G+A I+ + RF+ E+R + +G
Sbjct: 1020 MDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNG 1079
Query: 2978 VLFFLKQQSQFLCLAVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSA----SKAIQVFLLG 3033
++ + S F L ++ G L + YDFG P+ L A +K ++ ++
Sbjct: 1080 LILLMVNGSMFFRLEMRNGYLHVFYDFGF---SGGPVHLEDTLKKAQINDAKYHEISIIY 1136
Query: 3034 GSRKRVLVRVERATVYSVEQDNDLELADAYYLGGVPPDQLPP-SLRRLFPTGGSVRGCVK 3092
+ K++++ V+R V S++ + Y+GG PP+ L +LR P + RGC+K
Sbjct: 1137 HNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
Query: 3093 GIKALGKYVD-LKRLNTTGVSAGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGF 3151
G + K + L++ T GV GC D L+ R F+G F+ ++ ++ G GF
Sbjct: 1197 GFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFI-ASIQKISFFDG-FEGGF 1254
Query: 3152 GFHSAQDSALLYYRASPDGLCQVSLQQGRVSLQLLRTEVKT-QAGFADGAPHYVAFYSNA 3210
F + Q + LL+Y AS + +SL G V + + +V++ + DG H+V +
Sbjct: 1255 NFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSP 1314
Query: 3211 TGVWLYVD-DQLQQMKPHRGPPPELQPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQR 3269
T L VD ++ P +G + Q + + GG P S NF+GCISN + R
Sbjct: 1315 TRYELIVDKSRVGSKNPTKGKIEQTQASEK---KFYFGGSPISAQYANFTGCISNAYFTR 1371
Query: 3270 LLGPQRVFDLQQNLGSVNVSTGCAPALQAQTPGLGPRGLQATARKASRRSR------QPA 3323
+ V D Q+ V+ S P + L +G + KAS+ + P+
Sbjct: 1372 VDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPS 1431
Query: 3324 RHPACMLPPHLRTTRDS--------------YQFGGSLSSHLEFVGILARHRNWPSLSMH 3369
P + P T R+S YQ+GG+ +S EF + S+
Sbjct: 1432 WDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIR 1491
Query: 3370 VLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVS 3429
+ RSS G++ + + + + + LFL++G V +L+ +S+++ G WH V
Sbjct: 1492 LRTRSSHGMIFYVSD-QEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVI 1550
Query: 3430 VRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSKLPVT--VGF 3487
E++ LV DG R + P + A +++GG+ + + F
Sbjct: 1551 FIRERSSGRLVIDGLRVLEESLPPTE---ATWKIKGPIYLGGVAPGKAVKNVQINSIYSF 1607
Query: 3488 SGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLEL 3547
SGC+ L+L+G + + ++ VTPC GP+E G +F GG + LD +
Sbjct: 1608 SGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAF 1667
Query: 3548 EVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHR 3607
EVRP + +G + H G + YL + + QV+++ ++G +FSTSVT LCDG+WHR
Sbjct: 1668 EVRPRSSSGTLVH-GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHR 1726
Query: 3608 LAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA--YCGCM 3665
+ V++ NV++L+VD++ NH VGPL P+++GG+PE + P+ + GC+
Sbjct: 1727 ITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCI 1786
Query: 3666 RRLAVNRSPVAMTRSVEVHGAVGASGCPAA 3695
R ++ PV+ +++ V GAV + CPAA
Sbjct: 1787 RHFVIDGHPVSFSKAALVSGAVSINSCPAA 1816
Score = 242 bits (617), Expect = 6e-63
Identities = 108/216 (50%), Positives = 141/216 (65%), Gaps = 11/216 (5%)
Query: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900
+ ++C GF+ + G CVPC C+G+S+ CL GSG CV CQ NT G HCE+C G++
Sbjct: 63 AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
Query: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958
S R P C CPCPL +N FAE C + G +C+C YAG +CERCAPG++GN
Sbjct: 119 GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
Query: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018
PL++GS+C+ CDCSGN DPNL+F DCD +TG CR CLR+TTG +CE CAPG+YG+A +
Sbjct: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
Query: 2019 NCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRC 2054
NC C+ CG CD +G CL + CD+C
Sbjct: 237 NCAVCN---CGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 103 bits (256), Expect = 4e-21
Identities = 71/231 (30%), Positives = 98/231 (42%), Gaps = 46/231 (19%)
Query: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412
+ EC C+C G++ +C LDG+ G C+ CQ +TTG +CE+CL G+
Sbjct: 76 SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117
Query: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466
+P C+ C C ++F + +C G RC C N++G C+ CA G+
Sbjct: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524
G P +L CDCS D G+C C N G
Sbjct: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
Query: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT-CDRC 574
CE CAPG+YG C+ CD TG+C GFE T CD+C
Sbjct: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGCDKC 269
Score = 102 bits (254), Expect = 7e-21
Identities = 73/244 (29%), Positives = 98/244 (40%), Gaps = 42/244 (17%)
Query: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553
SA G Q +PRV P E C GF+ C PC C+ + C
Sbjct: 40 SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91
Query: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601
+G C C+ G C++C GY + CQ C C E C +
Sbjct: 92 LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651
A RC+C +AGP+C+RC PGY+G P C+ C C DP + G CR
Sbjct: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
Query: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
C TG C+ C+PG++G +C C+C CD +G+C C
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGC 266
Query: 708 DTCV 711
D CV
Sbjct: 267 DKCV 270
Score = 100 bits (250), Expect = 2e-20
Identities = 66/198 (33%), Positives = 90/198 (45%), Gaps = 33/198 (16%)
Query: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487
PC C+ C G C C + G C +C GY G P C+PC C
Sbjct: 81 PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538
A C G +CIC P+C C P +G L+G C++C+CSG L
Sbjct: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
Query: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593
CD +GQC+ C N TG +C+ C+PG++G R C C+C G CD +T
Sbjct: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252
Query: 1594 GQCYCKENVQGPK-CDQC 1610
G+C +E + P CD+C
Sbjct: 253 GEC-LEEGFEPPTGCDKC 269
Score = 84.3 bits (207), Expect = 2e-15
Identities = 61/211 (28%), Positives = 85/211 (40%), Gaps = 24/211 (11%)
Query: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716
A ++C+ GF S CVPC C+ + C SG C C+ TG C+ C+ G
Sbjct: 63 AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768
+C+ C LA + V C+C + GP+C+RC PG++G
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
Query: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826
C +C C + E C TGQC C + G C C G++G D C
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
Query: 827 RSCRCD-------IGGALGQSCEPRTGVCRC 850
C C G L + EP TG +C
Sbjct: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 83.2 bits (204), Expect = 4e-15
Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%)
Query: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533
C PCDC C + +G C+ C T C C G + G C+ C C P
Sbjct: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137
Query: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586
+ + +C +G +C C N G C+ C+PG++G P C+ CDC + P
Sbjct: 138 HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195
Query: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
+ CD +TGQC C N G KC++C+ G + DA K C C C G
Sbjct: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
Score = 77.0 bits (188), Expect = 3e-13
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 69/250 (27%)
Query: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
++ G CV C+G+++ C D CQ NT G C++C G+ +
Sbjct: 74 TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124
Query: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406
+ CQ C C A CY + G V C + G NCE
Sbjct: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167
Query: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459
RC PG+Y +PL C++C+C + F D C+++TG+C C N +G +C+
Sbjct: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222
Query: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
CA G+ G D R + +C+ G C D G CL +
Sbjct: 223 RCAPGYYG------------DAR---------IAKNCAVCNCGGGPC--DSVTGECLEEG 259
Query: 520 NFQGTHCELC 529
T C+ C
Sbjct: 260 FEPPTGCDKC 269
Score = 70.5 bits (171), Expect = 3e-11
Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 29/161 (18%)
Query: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365
A++C K+ ++C C N G C+RC PG+ P + C+ C+C G++
Sbjct: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193
Query: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
DP + + + G C +C +TTG CERC PG+Y +
Sbjct: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237
Query: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFT 466
C CNC G C+ +TG C CD C T
Sbjct: 238 CAVCNCGG----GPCDSVTGECLEEGFEPPTGCDKCVWDLT 274
Score = 65.9 bits (159), Expect = 7e-10
Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%)
Query: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562
+PP C F H L G C C+C+G + C SG C C+ N TG C+
Sbjct: 60 LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111
Query: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611
C G+ G P+ C+PC C H A A C G +C C EN GP C++C+
Sbjct: 112 KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170
Query: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635
G + C +C C G ++
Sbjct: 171 PGYYGNPLLIGSTCKKCDCSGNSD 194
Score = 62.8 bits (151), Expect = 6e-09
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883
C+C +Y G +C+ CAPG+Y + L +G C C C G+SD C +G C +C
Sbjct: 155 CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
Query: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915
NT G CERC G+ + C C C
Sbjct: 213 LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243
Score = 59.3 bits (142), Expect = 7e-08
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765
C G N FP+ GS + + DP PE P + + P+ ++C GF+
Sbjct: 21 CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74
Query: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822
C C C+ G EC G+G C C+ + G+ C C DG+ G + A
Sbjct: 75 LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867
F C+ C C + +SC + G C C N GP C A +Y
Sbjct: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Score = 53.5 bits (127), Expect = 4e-06
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 34/122 (27%)
Query: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478
L + + C C G + P C+ GQC C + G C RCA GY+G
Sbjct: 178 LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538
NC C+CG CD +TG+C+ G P GC++C + +L
Sbjct: 236 KNCAVCNCGGGPCDSVTGECL----------------EEGFEPPTGCDKC------VWDL 273
Query: 1539 TD 1540
TD
Sbjct: 274 TD 275
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 513 bits (1320), Expect = e-144
Identities = 282/752 (37%), Positives = 386/752 (51%), Gaps = 66/752 (8%)
Query: 1456 QCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCG--ARLC--DELT------ 1495
QC C + G C+RC GY P C C+C A+ C DE
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 1496 ----------GQCI-CPPRTIPPDCLLC-----QPQTFGCHPLVGCEECNCSGPGIQELT 1539
G CI C T+ +C C +P + C CNC G
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 1540 DPTCDTDS--------GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDP 1591
D S GQC C+ TG +CD C G+ YP C C C+ G+A +P
Sbjct: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD--EP 466
Query: 1592 LTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDME 1651
TG C CKENV+G CD+C G ++L NP+GC+ CFCFG ++ C S S+ + M
Sbjct: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMS 526
Query: 1652 GWV---LLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSY 1708
GW+ L+S + + G + + V + + P+ YW AP +YLG++++++
Sbjct: 527 GWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLA---PKYYWAAPEAYLGNKLTAF 583
Query: 1709 GGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMSI-TFLEPAYPTPGHVHRGQLQLVEG 1767
GG L+Y + + V + S DV+++GN +++ T E P + ++LV
Sbjct: 584 GGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPE 643
Query: 1768 NFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVF-LRRVALEVASP-AGQGALA 1825
NF+ ++ + R++LM VLA++ L IRA ++ A++ L V+L++AS A +A
Sbjct: 644 NFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVA 703
Query: 1826 SNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQH 1885
++VE C CP Y G SC+ C G+YR LF G C PC+CHGH+ C GVC+ C H
Sbjct: 704 ADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV-HGVCIACAH 762
Query: 1886 NTEGAHCERCQAGFVS--SRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGG-RTQC-LCKP 1941
NT G HCE+C GF SR P C C CPL++ SNNF+ C L G C C P
Sbjct: 763 NTTGVHCEQCLPGFYGEPSRGTPG-DCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
Query: 1942 GYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGP 2001
GY+GA CERCA G++GNP V G SC PCDCSGN DP+ CD +TG C CL +T G
Sbjct: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEA-GHCDSVTGECLKCLGNTDGA 880
Query: 2002 RCEICAPGFYGNALLPGNCTRCDCTPCGTEA--CDPHSGHCLCKAGVTGRRCDRCQEGHF 2059
CE CA GFYG+A+ NC C+C G+ + C +G C CK VTG++CD+C G++
Sbjct: 881 HCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940
Query: 2060 GFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC 2119
G D GCRPC C A S+ GQCHC PG G +C CA G++ + C C C
Sbjct: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDC 1000
Query: 2120 P--GGRCDPHTGRCNCPPGLSGERCDTCSQQH 2149
P CDP TG C CPP G +C+ C H
Sbjct: 1001 PHTQNTCDPETGECVCPPHTQGVKCEECEDGH 1032
Score = 451 bits (1160), Expect = e-126
Identities = 241/562 (42%), Positives = 321/562 (57%), Gaps = 90/562 (16%)
Query: 23 LLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYC 82
+L+ L L AA+ R+ L P NLA A I+ +ATCGE+ P +++C
Sbjct: 5 VLLVLLLCVAAQCRQRG-----LFPAILNLASNAHISTNATCGEKGP---------EMFC 50
Query: 83 KLVGGPVAGGDPNQTIRGQYCDIC--TAANSNKAHPASNAIDGTERWWQSPPLSRGLEYN 140
KLV P + +R C IC +AN + HP S+AIDGT WWQSP + G EY+
Sbjct: 51 KLVEHV-----PGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYH 105
Query: 141 EVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERF- 199
V +TLDL QVF VAYV+IK AN+PRP W+LERS+D G T+ PWQ++A S +CL R+
Sbjct: 106 WVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYN 164
Query: 200 -----GPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFT 254
GP T DD ICT+ YSR+VPLE+GEI SL+NGRP A + S P L EFT
Sbjct: 165 ITPRRGPPTYRA---DDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLS--PKLLEFT 219
Query: 255 KATNVRLRFLRTNTLLGHLMGKALR-----DPTVTRRYYYSIKDISIGGRCVCHGHADAC 309
A +RLR R TL LM + R DP VTRRYYYSIKDIS+GG C+C+GHA +C
Sbjct: 220 SARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC 279
Query: 310 DAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCY 369
+ T +LQC C+HNTCG +C+RCCPG++QQPW+P T +S N C++CNC+ A DCY
Sbjct: 280 PWDETTK--KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCY 337
Query: 370 YDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRC 429
YD V +++ S + G ++GGGVCI+C +T G+NCE C+ G+YR CR C
Sbjct: 338 YDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPC 397
Query: 430 NCE---------------SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPT 474
NC+ SD +G G+C C+ ++GE+CD C G+ +P+C
Sbjct: 398 NCDPVGSLSSVCIKDDLHSDLHNG---KQPGQCPCKEGYTGEKCDRCQLGYKDYPTC--- 451
Query: 475 PSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY 534
V+C C+ G+ + +P G C+CK N +G C+ C PGFY
Sbjct: 452 -----------------VSCGCNPVGSASD----EPCTGPCVCKENVEGKACDRCKPGFY 490
Query: 535 G------PGCQPCQCSSPGVAD 550
GC C C GV+D
Sbjct: 491 NLKEKNPRGCSECFCF--GVSD 510
Score = 365 bits (937), Expect = e-100
Identities = 215/640 (33%), Positives = 315/640 (49%), Gaps = 76/640 (11%)
Query: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN--CRPCDCG--A 1488
+G RPC C G+ C GQC C V G+ C RCA G++ + + C PCDC
Sbjct: 946 HGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQ 1004
Query: 1489 RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG 1548
CD TG+C+CPP T C C+ +G VGC+ CNCS G T CD +G
Sbjct: 1005 NTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGS---THHRCDVVTG 1061
Query: 1549 QCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCD---------PLTGQCYCK 1599
C+C+ GR CD CS G+ +P C PCDC GT+ C+ TG C CK
Sbjct: 1062 HCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCK 1121
Query: 1600 ENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRS-SSYTRQEFVDMEGWVLLST 1658
ENV GP+C++C GTF+L A NP GC+ CFC G + C Y R V L +
Sbjct: 1122 ENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTP-------VTLGS 1174
Query: 1659 DRQVVPHERQPGTEMLRADLRHVPEAVPEAFPEL----------------YWQAPPSYLG 1702
D+ ++ Q ++LR E V P+ YW+ P + G
Sbjct: 1175 DQPLLRVVSQ-------SNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQG 1227
Query: 1703 DRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQM--SITFLEPAYPTPGHVHRG 1760
D++ +YGG L+Y + + G E P V+++G ++ + +++ P G
Sbjct: 1228 DQLMAYGGKLKYSVAFYSLDGVGTSNFE--PQVLIKGGRIRKQVIYMDAPAPENGVRQEQ 1285
Query: 1761 QLQLVEGNFRH--TETRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASP 1818
++ + E +++ + + V+RE+ M VL+ +E + I+A + Q + +++EV
Sbjct: 1286 EVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRK 1345
Query: 1819 AG----QGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR--------CVPCQC 1866
A + +AS +E C+CP G SCQ+CAPG++R R CVPC C
Sbjct: 1346 AEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSC 1405
Query: 1867 HGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAE 1926
+ HSD C P +G C++C NT G HC+ C +G+ ++ C C CP S P+ +F+
Sbjct: 1406 NNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA-SFSP 1464
Query: 1927 GCVLRGGRT-QC-LCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDC 1984
CVL G +C C GY G CERC+ ++GNP G SCQ CDC+ +G + DC
Sbjct: 1465 TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGS---VHGDC 1521
Query: 1985 DPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCD 2024
D +G C C +G RC+ C P + L+ +C CD
Sbjct: 1522 DRTSGQC-VCRLGASGLRCDECEP---RHILMETDCVSCD 1557
Score = 281 bits (718), Expect = 1e-74
Identities = 159/484 (32%), Positives = 214/484 (44%), Gaps = 67/484 (13%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
C C G +C+ C G+ ++ CQ C C+GHA +C
Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
Query: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE----SDFTD 437
GVCI C H+TTGV+CE+CLPGFY P+ +P C+ C C S+
Sbjct: 755 ---------GVCIACAHNTTGVHCEQCLPGFYGEPSR--GTPGDCQPCACPLTIASNNFS 803
Query: 438 GTCEDLTGR---C-YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVN 493
TC G C +C P +SG C+ CA+G+ G P+ +P V
Sbjct: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT---------------VPGESCVP 848
Query: 494 CDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG-----CQPCQCSSPG 547
CDCS A D G CL C N G HCE CA GFYG C+ C+C G
Sbjct: 849 CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKG 908
Query: 548 VADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDEAGR 604
C +TG C C+ G CD+C GY+ C+ C CS AG++ +GC + G+
Sbjct: 909 SHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQ 968
Query: 605 CLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
C C P AG CDRC G++ + + CD + G C C P G C+EC
Sbjct: 969 CHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEEC 1028
Query: 665 SPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCE 721
G G+ + C C+CS GS H CD +G C C+ + G CD C G +FP C
Sbjct: 1029 EDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCV 1088
Query: 722 AGSCHPAGLAPVDPALPEAQVPCM-------CRAHVEGPSCDRCKPGFWGLSPSNPEGCT 774
C G + L + C+ C+ +V GP C+ C+ G + L NP GC+
Sbjct: 1089 PCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCS 1148
Query: 775 RCSC 778
C C
Sbjct: 1149 PCFC 1152
Score = 277 bits (709), Expect = 1e-73
Identities = 416/1822 (22%), Positives = 746/1822 (40%), Gaps = 236/1822 (12%)
Query: 1994 CLRHTTGPRCEICAPGFYGNALLPGN----------CTRCDCTPCGTEACDPHSGHCL-C 2042
C T G C+ CAPG++ L G+ C C C ++ CDP++G CL C
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN-HSDTCDPNTGKCLNC 1422
Query: 2043 KAGVTGRRCDRCQEGHFG--FDGCGGCRPCACG---PAAEGSECHPQSG---QCH-CRPG 2093
G CD C G++G C CAC PA+ C + +C C G
Sbjct: 1423 GDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLG 1482
Query: 2094 TMGPQCRECAPGYWGLPEQ---GCRRCQCPG-----GRCDPHTGRCNCPPGLSGERCDTC 2145
G C C+ Y+G P+ C++C C G CD +G+C C G SG RCD C
Sbjct: 1483 YEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
Query: 2146 SQQHQVPVPGGPVGHSIHCEVC-DHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWAR 2204
+H + C C D CV +LL+DL+ G + +++ L GI + +
Sbjct: 1543 EPRH--------ILMETDCVSCDDECVGVLLNDLDEIGDAVLSLN--LTGI--IPVPYGI 1590
Query: 2205 LHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQL 2264
L L + LQ L + +LE + +++ +L + R+ ++
Sbjct: 1591 LSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRM-------LASTQKV 1643
Query: 2265 LAGTEATLGHAKTLLAAIRAVDRTLSELMSQT-------GHLGLANASAPSGEQLLRTLA 2317
TE ++ L AI + +++E+M +T L N++ + +Q +L
Sbjct: 1644 NRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLL 1703
Query: 2318 EVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQH 2377
E+ M+ RD A EL AA+ LL+++QE EE + L L++H
Sbjct: 1704 EI------MQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKH 1757
Query: 2378 EAGLMDLREALNRAVDATREAQE-----LNSRNQERLEEALQRKQELSRDNATL---QAT 2429
L EAL R +A + +N+ +E ++ L ++E + + + +
Sbjct: 1758 NNEL-KAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGL 1816
Query: 2430 LHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAE 2489
+ AA +V L L+ +++L +A + L+ M + + LV AE
Sbjct: 1817 IDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMS----QRNAVDLVYRAE 1872
Query: 2490 AHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHT 2549
HA + +LA L S + ++ ++ A A+ + I ++ +E+ A A + T
Sbjct: 1873 DHAAEFQRLADVLYSGLENIR--NVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTET 1930
Query: 2550 WATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLG--LVWAALQGARTQLRDVRAKKDQL 2607
+++ + LV + + S+ L+E L L AL+ + + + R +++ +
Sbjct: 1931 --SLLSESLVSNGKAAVQRSS----RFLKEGNNLSRKLPGIALELSELRNKTNRFQENAV 1984
Query: 2608 EAHIQAAQAMLAMDT--DETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYE 2665
E Q +++L + K A K +A A +A + + + +
Sbjct: 1985 EITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLS 2044
Query: 2666 GLRG---------QDLGQAVLDAGHSVSTLE---KTLPQLLAKLSILENRGVHNASLALS 2713
+ QD A L AG V +E L L L +LE LS
Sbjct: 2045 RVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEEN--------LS 2096
Query: 2714 ASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEP 2773
++ ++ LI+QAR A+ +KV + + R ++ P+ Y L ++ EP
Sbjct: 2097 RNLSEIKLLISQARKQAASIKVAVSAD-RDCIRAYQPQ--ISSTNYNTLTLNVKTQEP-- 2151
Query: 2774 GQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGE-QFAAVS 2832
D + Y+GS A+ D++ V +R +V +++ LG + D I + ++ ++
Sbjct: 2152 -----DNLLFYLGSSTAS-DFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIH 2205
Query: 2833 LDRTLQFGHMSVTVERQMIQETKGDT---VAPGAEGLLNLRPDDFVFYVGGYPSTFTPPP 2889
+ R G +SV ++M K T +PG +L++ +F VGG P
Sbjct: 2206 VARFGNIGSLSV---KEMSSNQKSPTKTSKSPGTANVLDVNNSTLMF-VGGLGGQIKKSP 2261
Query: 2890 LLRFPGYRGCIEMDTLNEEVVSLYNF-ERTFQLDTAVDRPCARSKSTGDPWLTDGSYLDG 2948
++ ++GC+ LN + + L+N+ ER + R C S DP + DG
Sbjct: 2262 AVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKC-----RGCFGSSQNEDP----SFHFDG 2312
Query: 2949 TGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQ--QSQFLCLAVQEGSLVLLYDFGA 3006
+G++ + S +T + S +G+L +L FL + + G + ++ D G+
Sbjct: 2313 SGYSVVE-KSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGS 2371
Query: 3007 GLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLEL------- 3059
G P+ + +RK+ ++ V A S ++ E
Sbjct: 2372 G-----PITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDL 2426
Query: 3060 ----ADAYYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGC 3115
D Y+GG+P ++ +RR T V GC+K ++ DL R N+ GV GC
Sbjct: 2427 NRLDKDPIYVGGLPRSRV---VRRGVTTKSFV-GCIKNLEISRSTFDLLR-NSYGVRKGC 2481
Query: 3116 TADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVS 3175
+ + R+++F G++ L +++P + + + F + S ++ D +
Sbjct: 2482 LLEPI--RSVSFLKGGYIELPPKSLSPESEWLVT---FATTNSSGIILAALGGDVEKRGD 2536
Query: 3176 LQQGRV---SLQLLRTEVKTQAGFADG---------APHYVAFYSNATGVWLYVDDQLQQ 3223
++ V S+ L+ ++ DG AP A + L + ++
Sbjct: 2537 REEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIIT 2596
Query: 3224 MKPHRGPPPEL------QPQPEGPPRLLLGGLPE-SGTIY-----NFSGCISNVFVQRLL 3271
++ P E+ + + L +GG+PE GT +F GCI N+
Sbjct: 2597 VQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNL------ 2650
Query: 3272 GPQRVFDLQQNLGSVNVSTGCAPALQAQTPGLGPRGLQATARKASRRSRQPARHP-ACML 3330
+F+L+ L N + G + T L R A + S+ +P P C++
Sbjct: 2651 ----IFNLE--LLDFNSAVG-HEQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQCVV 2703
Query: 3331 PPHLRTTRDSYQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSP 3390
L ++QFG + +SH + R S+ + + +S GL+ + A
Sbjct: 2704 DAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQADY 2763
Query: 3391 S-LALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQ 3449
+ L L HF+ + G G R + G+WH V + K + + DG +
Sbjct: 2764 AVLQLHGGRLHFMFDL-GKG-RTKVSHPALLSDGKWHTVKTDYVKRKGFITVDG-----R 2816
Query: 3450 EGPHRQ--HQGAEHPQPHTLFVGGLPASSHSSKL-PVTVGFSGCVKRLRLHGRPL--GAP 3504
E P G ++GGLP+ + K+ +T C+ + ++ + L +P
Sbjct: 2817 ESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSP 2876
Query: 3505 TRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQA 3564
V C + G +F GSG + DV + LE R + G++ + A
Sbjct: 2877 VSAFTVNRC-YAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTA 2935
Query: 3565 RTPPYLQLQVTEKQVLLRADDGAGEFSTSV--TRPSVLCDGQWHRLAVMKSGNVLRLEVD 3622
+ + L++ + +VL ++GAG + + +VLCDG+WH L KS + + L VD
Sbjct: 2936 KVDA-IGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVD 2994
Query: 3623 -----AQSNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQ--PWPPAYCGCMRRLAVNRSPV 3675
A+S HT + + P+Y+GG P + + ++ GC+R+LA+ +SP
Sbjct: 2995 GNAVGAESPHT----QSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQ 3050
Query: 3676 A----MTRSVEVHGAVGASGCP 3693
+R+ E+HG V CP
Sbjct: 3051 VQSFDFSRAFELHG-VFLHSCP 3071
Score = 242 bits (618), Expect = 4e-63
Identities = 154/479 (32%), Positives = 208/479 (43%), Gaps = 78/479 (16%)
Query: 395 DCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY-CRPNF 453
+C TG +CE CL G+YR +C+ C C + C ++ G C C N
Sbjct: 710 ECPQGYTGTSCESCLSGYYRVDGILFGG--ICQPCECHGHAAE--C-NVHGVCIACAHNT 764
Query: 454 SGERCDVCAEGFTGFPS------CYP-----TPSSSNDTREQVLPAGQIVNCDCSAAGTQ 502
+G C+ C GF G PS C P T +S+N + L G V CD
Sbjct: 765 TGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDW------ 818
Query: 503 GNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG----PG--CQPCQCSS---PGVADDRC 553
C P + G CE CA G+YG PG C PC CS P A C
Sbjct: 819 --------------CAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAG-HC 863
Query: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL----CQLCGCSPAGTLPEGCD-EAGRCLC 607
D TG+C +C +GA C+RCA G++ + C+ C C G+ C E G C C
Sbjct: 864 DSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDC 923
Query: 608 QPEFAGPHCDRCRPGYHGFPN---CQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
+P G CD+C GY+G + C+ C C G++ C G C C PG G C C
Sbjct: 924 KPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRC 983
Query: 665 SPGFHGFP--SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPY--- 719
+ GF+ + SC PC C + CDP +G+C C P G++C+ C G + +
Sbjct: 984 AHGFYAYQDGSCTPCDCPHTQN---TCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVG 1040
Query: 720 CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCD 779
C+A +C G C C++ G +CD+C G+ C C CD
Sbjct: 1041 CQACNCSLVG--STHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD-----CVPCDCD 1093
Query: 780 LRGTLG-------GVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
LRGT G G+ C TG C CK +V G C C++G F L + GC C C
Sbjct: 1094 LRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC 1152
Score = 239 bits (610), Expect = 4e-62
Identities = 152/456 (33%), Positives = 195/456 (42%), Gaps = 74/456 (16%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C ++G C+ C G+ + +L G C+C + N
Sbjct: 709 CECPQGYTGTSCESCLSGYYRV--------------DGILFGGICQPCECHGHAAECNVH 754
Query: 507 RKDPRVGRCL-CKPNFQGTHCELCAPGFYG------PG-CQPCQCSSPGVADD---RC-- 553
G C+ C N G HCE C PGFYG PG CQPC C +++ C
Sbjct: 755 ------GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHL 808
Query: 554 -DPDTGQCR-CRVGFEGATCDRCAPGYFHFPL-----CQLCGCSPAGTLPEG--CDEA-G 603
D D C C G+ GA C+RCA GY+ P C C CS E CD G
Sbjct: 809 NDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868
Query: 604 RCL-CQPEFAGPHCDRCRPGYHG----FPNCQACTCDPRGALDQLCGAG-GLCRCRPGYT 657
CL C G HC+RC G++G NC+AC C +G+ +C GLC C+P T
Sbjct: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
Query: 658 GTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGA 714
G C +C G++G S C PC+CS GS+ C GQC C P V G RCD C G
Sbjct: 929 GQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGF 987
Query: 715 YNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCT 774
Y + + GSC P C+C H +G C+ C+ G WG GC
Sbjct: 988 YAY---QDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQ 1042
Query: 775 RCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIG 834
C+C L G+ C TG C CK G+AC C G+ D+ C C CD+
Sbjct: 1043 ACNCSLVGSTHH--RCDVVTGHCQCKSKFGGRACDQCSLGY-----RDFPDCVPCDCDLR 1095
Query: 835 GALGQSCE---------PRTGVCRCRPNTQGPTCSE 861
G G +C TG C C+ N GP C+E
Sbjct: 1096 GTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNE 1131
Score = 203 bits (517), Expect = 2e-51
Identities = 125/388 (32%), Positives = 163/388 (42%), Gaps = 55/388 (14%)
Query: 512 VGRCLCKPNFQGTHCELCAPGFY-------GPGCQPCQCSSPGVADDRCDPDTGQCRCRV 564
V C C + GT CE C G+Y G CQPC+C C+ C
Sbjct: 706 VEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAA---ECNVHGVCIACAH 762
Query: 565 GFEGATCDRCAPGYFHFPL------CQLCGC---------SPAGTLPEGCDEAGRCLCQP 609
G C++C PG++ P CQ C C SP L +G DE C P
Sbjct: 763 NTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDG-DEVVCDWCAP 821
Query: 610 EFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCRCRPGYTGTA 660
++G C+RC GY+G P +C C C DP A G +C G
Sbjct: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
Query: 661 CQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYN 716
C+ C+ GF+G +C C C +GS A C +G C C+P VTG +CD C+ G Y
Sbjct: 882 CERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYG 941
Query: 717 FPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGC 773
C +C AG D E Q C C V G CDRC GF+ + C
Sbjct: 942 LDSGHGCRPCNCSVAGSVS-DGCTDEGQ--CHCVPGVAGKRCDRCAHGFYAYQDGS---C 995
Query: 774 TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI 833
T C C C P TG+C C PH G C C+DG +G D GC++C C +
Sbjct: 996 TPCDCPHTQNT-----CDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQACNCSL 1048
Query: 834 GGALGQSCEPRTGVCRCRPNTQGPTCSE 861
G+ C+ TG C+C+ G C +
Sbjct: 1049 VGSTHHRCDVVTGHCQCKSKFGGRACDQ 1076
Score = 196 bits (499), Expect = 3e-49
Identities = 127/391 (32%), Positives = 176/391 (45%), Gaps = 45/391 (11%)
Query: 1833 CPASYRGDSCQECAPGFYRD--VKGLFLGRCVPCQCHGHSD-----RCLPGSGVCVDCQH 1885
C Y G C+ CA G+Y + V G CVPC C G+ D C +G C+ C
Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPG---ESCVPCDCSGNVDPSEAGHCDSVTGECLKCLG 875
Query: 1886 NTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAG 1945
NT+GAHCERC GF + C +C C + + + C L G C CKP G
Sbjct: 876 NTDGAHCERCADGFYGDAVT-AKNCRACECHVK---GSHSAVCHLETGL--CDCKPNVTG 929
Query: 1946 ASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C++C G++G L G C+PC+CS G SD G C C+ G RC+
Sbjct: 930 QQCDQCLHGYYG--LDSGHGCRPCNCSVAGS----VSDGCTDEGQCH-CVPGVAGKRCDR 982
Query: 2006 CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG 2065
CA GFY A G+CT CDC P CDP +G C+C G +C+ C++GH+G+D
Sbjct: 983 CAHGFY--AYQDGSCTPCDC-PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV 1039
Query: 2066 GCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC----- 2119
GC+ C C + C +G C C+ G C +C+ GY P+ C C C
Sbjct: 1040 GCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD--CVPCDCDLRGT 1097
Query: 2120 PGGRCD---------PHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHS-IHCEVCDH 2169
G C+ TG C C + G +C+ C + P+G S C H
Sbjct: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
Query: 2170 CVVLLLDDLERAGALLPAIHEQLRGINASSM 2200
+ L+D R L + LR ++ S++
Sbjct: 1158 -LCSELEDYVRTPVTLGSDQPLLRVVSQSNL 1187
Score = 194 bits (494), Expect = 1e-48
Identities = 124/370 (33%), Positives = 160/370 (43%), Gaps = 84/370 (22%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C C G+ D +A D +C C NT G C+RC GF A +A C++
Sbjct: 849 CDCSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGFY------GDAVTAKNCRA 901
Query: 359 CNCY---GHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRS 415
C C+ H+ C+ + G+C DC+ + TG C++CL G+Y
Sbjct: 902 CECHVKGSHSAVCHLET------------------GLC-DCKPNVTGQQCDQCLHGYYG- 941
Query: 416 PNHPLDSPHVCRRCNCE--SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYP 473
LDS H CR CNC +DG ++ G+C+C P +G+RCD CA GF +
Sbjct: 942 ----LDSGHGCRPCNCSVAGSVSDGCTDE--GQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
Query: 474 TPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGF 533
TP CDC TQ N C DP G C+C P+ QG CE C G
Sbjct: 996 TP------------------CDCPH--TQ-NTC--DPETGECVCPPHTQGVKCEECEDGH 1032
Query: 534 YG----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGC 589
+G GCQ C CS G RCD TG C+C+ F G CD+C+ GY FP C C C
Sbjct: 1033 WGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDC 1092
Query: 590 SPAGTLPEGC----------DEAGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC 634
GT + C +E G C C+ GP C+ CR G C C C
Sbjct: 1093 DLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC 1152
Query: 635 DPRGALDQLC 644
L LC
Sbjct: 1153 ---SGLSHLC 1159
Score = 177 bits (450), Expect = 1e-43
Identities = 111/345 (32%), Positives = 151/345 (43%), Gaps = 49/345 (14%)
Query: 556 DTGQCRCRVGFEGATCDRCAPGYFHFP------LCQLCGCSPAGTLPEGCDEAGRCL-CQ 608
D C C G+ G +C+ C GY+ +CQ C C G E C+ G C+ C
Sbjct: 705 DVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECH--GHAAE-CNVHGVCIACA 761
Query: 609 PEFAGPHCDRCRPGYHGFPN------CQACTCDPRGALDQLC-------GAGGLCR-CRP 654
G HC++C PG++G P+ CQ C C A + G +C C P
Sbjct: 762 HNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
Query: 655 GYTGTACQECSPGFHGFP-----SCVPCHCSA--EGSLHAACDPRSGQC-SCRPRVTGLR 706
GY+G C+ C+ G++G P SCVPC CS + S CD +G+C C G
Sbjct: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
Query: 707 CDTCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGF 762
C+ C G Y C A CH G L C C+ +V G CD+C G+
Sbjct: 882 CERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGL--CDCKPNVTGQQCDQCLHGY 939
Query: 763 WGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQAD 822
+GL + GC C+C + G+ V++ GQC C P V G+ C C GF+
Sbjct: 940 YGLDSGH--GCRPCNCSVAGS---VSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGS 994
Query: 823 YFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
C C C +C+P TG C C P+TQG C E H+
Sbjct: 995 ---CTPCDCP---HTQNTCDPETGECVCPPHTQGVKCEECEDGHW 1033
Score = 129 bits (323), Expect = 7e-29
Identities = 69/221 (31%), Positives = 93/221 (42%), Gaps = 50/221 (22%)
Query: 604 RCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRG--------------- 638
+C C+ G C+RC PGYH P C+AC C +
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 639 --ALDQLCGAGGLCRCRPGYTGTACQECSPGFHG--------FPSCVPCHCSAEGSLHAA 688
Q G G C G C+ C G++ C PC+C GSL +
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 689 C-----------DPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPAL 737
C + GQC C+ TG +CD C G ++P C + C+P G A +P
Sbjct: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCT 468
Query: 738 PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
PC+C+ +VEG +CDRCKPGF+ L NP GC+ C C
Sbjct: 469 G----PCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 128 bits (322), Expect = 9e-29
Identities = 74/245 (30%), Positives = 100/245 (40%), Gaps = 28/245 (11%)
Query: 650 CRCRPGYTGTACQECSPGFHGFPS------CVPCHC---SAEGSLHAACDPRSGQCSCRP 700
C C GYTGT+C+ C G++ C PC C +AE ++H C +C
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVC------IACAH 762
Query: 701 RVTGLRCDTCVPGAYNFPYCEA-GSCHPAG---------LAPVDPALPEAQVPC-MCRAH 749
TG+ C+ C+PG Y P G C P +P +V C C
Sbjct: 763 NTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPG 822
Query: 750 VEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQAC 808
G C+RC G++G E C C C C TG+C C + G C
Sbjct: 823 YSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
Query: 809 ASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
C DGF+G D CR+C C + G+ C TG+C C+PN G C + +Y
Sbjct: 883 ERCADGFYG-DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYG 941
Query: 869 PDLHH 873
D H
Sbjct: 942 LDSGH 946
Score = 115 bits (288), Expect = 8e-25
Identities = 72/225 (32%), Positives = 98/225 (43%), Gaps = 41/225 (18%)
Query: 1934 RTQCLCKPGYAGASCERCAPGFFGNP-----LVLGSSCQPCDCSGNG-----DPNLLFSD 1983
+ QC C+ G SC RC PG+ P + G++C+ C+C D ++
Sbjct: 287 KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQK 346
Query: 1984 CDPLT-------GACRGCLRHTTGPRCEICAPGFY-GNALLPGN---CTRCDCTPCG--T 2030
T G C CL++T G CE C G+Y + + P C C+C P G +
Sbjct: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLS 406
Query: 2031 EAC---DPHS--------GHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGS 2079
C D HS G C CK G TG +CDRCQ G+ + C C C P S
Sbjct: 407 SVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVS---CGCNPVGSAS 463
Query: 2080 ECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRCQCPG 2121
+ P +G C C+ G C C PG++ L E +GC C C G
Sbjct: 464 D-EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFG 507
Score = 111 bits (277), Expect = 2e-23
Identities = 74/232 (31%), Positives = 99/232 (42%), Gaps = 35/232 (15%)
Query: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNC--DCSAAGTQG 503
+C C N GE C+ C G+ P P SS +T E + +C D S A +
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQP-WRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKK 347
Query: 504 --NACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG---------CQPCQCSSPGVADD 551
N + G C+ C N G +CE C G+Y P C+PC C G
Sbjct: 348 SLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSS 407
Query: 552 RCDPDT-----------GQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTL-PEGC 599
C D GQC C+ G+ G CDRC GY +P C CGC+P G+ E C
Sbjct: 408 VCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPC 467
Query: 600 DEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLC-GAGGLC 650
G C+C+ G CDRC+PG++ +PRG + C G +C
Sbjct: 468 --TGPCVCKENVEGKACDRCKPGFYNLKE-----KNPRGCSECFCFGVSDVC 512
Score = 107 bits (268), Expect = 2e-22
Identities = 66/186 (35%), Positives = 79/186 (42%), Gaps = 36/186 (19%)
Query: 560 CRCRVGFEGATCDRCAPGYFHFPL--------------CQLCGCSPAGTLPEGCD-EAGR 604
C C G G +C CAPGY L C C C+ + CD G+
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHS---DTCDPNTGK 1418
Query: 605 CL-CQPEFAGPHCDRCRPGYHG-----FPNCQACTC--DPRGALDQLCGAGG-----LCR 651
CL C AG HCD C GY+G +C C C P + C G
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 652 CRPGYTGTACQECSPGFHGFP-----SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLR 706
C GY G C+ CS ++G P SC C C+ GS+H CD SGQC CR +GLR
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
Query: 707 CDTCVP 712
CD C P
Sbjct: 1539 CDECEP 1544
Score = 107 bits (266), Expect = 3e-22
Identities = 70/206 (33%), Positives = 89/206 (43%), Gaps = 38/206 (18%)
Query: 515 CLCKPNFQGTHCELCAPGFY----------GP-----GCQPCQCSSPGVADDRCDPDTGQ 559
C+C P G C+ CAPG++ GP C PC C++ D CDP+TG+
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN---HSDTCDPNTGK 1418
Query: 560 C-RCRVGFEGATCDRCAPGYF-----HFPLCQLCGC--SPAGTLPEGC----DEAGRC-L 606
C C G CD C GY+ C LC C SP + C D RC
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 607 CQPEFAGPHCDRCRPGYHGFP-----NCQACTCDPRGALDQLCG-AGGLCRCRPGYTGTA 660
C + G HC+RC Y+G P +CQ C C+P G++ C G C CR G +G
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
Query: 661 CQECSPGFHGFPS-CVPCHCSAEGSL 685
C EC P + CV C G L
Sbjct: 1539 CDECEPRHILMETDCVSCDDECVGVL 1564
Score = 106 bits (264), Expect = 5e-22
Identities = 74/238 (31%), Positives = 97/238 (40%), Gaps = 39/238 (16%)
Query: 396 CQHHTTGVNCERCLPGFYRSP--------NHPLDSPHVCRRCNCESDFTDGTCEDLTGRC 447
C T G +C+ C PG++R PL +P V CN SD TC+ TG+C
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD----TCDPNTGKC 1419
Query: 448 Y-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C N +G+ CDVC G+ G S++D + C S + C
Sbjct: 1420 LNCGDNTAGDHCDVCTSGYYG-----KVTGSASDCA--------LCACPHSPPASFSPTC 1466
Query: 507 ----RKDPRVGRCLCKPNFQGTHCELCAPGFYG----PG--CQPCQCSSPGVADDRCDPD 556
D R CL ++G HCE C+ +YG PG CQ C C+ G CD
Sbjct: 1467 VLEGDHDFRCDACLL--GYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
Query: 557 TGQCRCRVGFEGATCDRCAPGYFHFPL-CQLCGCSPAGTLPEGCDEAGRCLCQPEFAG 613
+GQC CR+G G CD C P + C C G L DE G + G
Sbjct: 1525 SGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTG 1582
Score = 98.2 bits (243), Expect = 1e-19
Identities = 68/214 (31%), Positives = 90/214 (42%), Gaps = 35/214 (16%)
Query: 443 LTGRCYCRPNFSGERCDVCAEGF--TGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAG 500
L C C P G C CA G+ P+ S R V P V C C+
Sbjct: 1358 LLENCVCPPGTVGFSCQDCAPGYHRGKLPA-----GSDRGPRPLVAPC---VPCSCN--- 1406
Query: 501 TQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG------PGCQPCQC--SSPGVADD 551
+ C DP G+CL C N G HC++C G+YG C C C S P
Sbjct: 1407 NHSDTC--DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSP 1464
Query: 552 RC----DPDTGQCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAGTLPEGCDE- 601
C D D C +G+EG C+RC+ Y+ P CQ C C+P G++ CD
Sbjct: 1465 TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCD 635
+G+C+C+ +G CD C P H +CD
Sbjct: 1525 SGQCVCRLGASGLRCDECEP-RHILMETDCVSCD 1557
Score = 93.6 bits (231), Expect = 3e-18
Identities = 64/225 (28%), Positives = 90/225 (40%), Gaps = 52/225 (23%)
Query: 650 CRCRPGYTGTACQECSPGFHGFP----------SCVPCHCSAEG--------------SL 685
C+C G +C C PG+H P +C C+C + SL
Sbjct: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSL 349
Query: 686 HAACDPRSGQC--SCRPRVTGLRCDTCVPGAYN----FPY----CEAGSCHPAGLAP--- 732
+ A R G +C G+ C+TC+ G Y PY C +C P G
Sbjct: 350 NTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVC 409
Query: 733 ----VDPALPEAQVP--CMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGG 786
+ L + P C C+ G CDRC+ G+ + C C C+ G+
Sbjct: 410 IKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGY-----KDYPTCVSCGCNPVGS--- 461
Query: 787 VAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
A +P TG C CK +V G+AC CK GF+ L + + GC C C
Sbjct: 462 -ASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 77.8 bits (190), Expect = 2e-13
Identities = 57/225 (25%), Positives = 75/225 (33%), Gaps = 44/225 (19%)
Query: 650 CRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACD--PRSGQCSCRPRVTGLRC 707
C C PG G +CQ+C+PG+H G L A D PR C P
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYH------------RGKLPAGSDRGPRPLVAPCVPCSCNNHS 1409
Query: 708 DTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSP 767
DTC P G C C + G CD C G++G
Sbjct: 1410 DTCDPNT--------GKC------------------LNCGDNTAGDHCDVCTSGYYGKVT 1443
Query: 768 SNPEGCTRCSCDLRGTLGGVAECQPGTGQCF----CKPHVCGQACASCKDGFFGLDQADY 823
+ C C+C C F C G+ C C ++G Q
Sbjct: 1444 GSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPG 1503
Query: 824 FGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
C+ C C+ G++ C+ +G C CR G C E H L
Sbjct: 1504 GSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHIL 1548
Score = 77.0 bits (188), Expect = 3e-13
Identities = 51/164 (31%), Positives = 72/164 (43%), Gaps = 26/164 (15%)
Query: 300 CVCHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C C+ H+D C DP +C C NT G CD C G+ + SA++C
Sbjct: 1403 CSCNNHSDTC------DPNTGKCLNCGDNTAGDHCDVCTSGYYGK-----VTGSASDCAL 1451
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C H+ + P + L+G + C C G +CERC +Y +P
Sbjct: 1452 CAC-PHSPPASFSP-------TCVLEGDHDFR--CDACLLGYEGKHCERCSSSYYGNPQT 1501
Query: 419 PLDSPHVCRRCNCE-SDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
P S C++C+C G C+ +G+C CR SG RCD C
Sbjct: 1502 PGGS---CQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
Score = 74.7 bits (182), Expect = 2e-12
Identities = 55/222 (24%), Positives = 81/222 (36%), Gaps = 51/222 (22%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANE----CQSCNCYGHATDCYYDPEVDRR 377
C C T G +C C PG+++ + C C+C H+ C DP
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--DPNT--- 1416
Query: 378 RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC----ES 433
G C++C +T G +C+ C G+Y S C C C +
Sbjct: 1417 -------------GKCLNCGDNTAGDHCDVCTSGYY---GKVTGSASDCALCACPHSPPA 1460
Query: 434 DFTDGTC---EDLTGRC-YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAG 489
F+ TC D RC C + G+ C+ C+ + G P P G
Sbjct: 1461 SFSP-TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ---------------TPGG 1504
Query: 490 QIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAP 531
CDC+ G+ C D G+C+C+ G C+ C P
Sbjct: 1505 SCQKCDCNPHGSVHGDC--DRTSGQCVCRLGASGLRCDECEP 1544
Score = 67.0 bits (162), Expect = 3e-10
Identities = 38/124 (30%), Positives = 49/124 (39%), Gaps = 20/124 (16%)
Query: 1427 LSLFYNNGARPCGCHEVGATGPTC-------------EPFGGQCPCHAHVIGRDCSRCAT 1473
+S + + RPC C VG+ C +P GQCPC G C RC
Sbjct: 386 VSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQP--GQCPCKEGYTGEKCDRCQL 443
Query: 1474 GYWGFPNCRPCDC---GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPL--VGCEEC 1528
GY +P C C C G+ + TG C+C C C+P + GC EC
Sbjct: 444 GYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC 503
Query: 1529 NCSG 1532
C G
Sbjct: 504 FCFG 507
Score = 62.0 bits (149), Expect = 1e-08
Identities = 124/524 (23%), Positives = 194/524 (37%), Gaps = 82/524 (15%)
Query: 2088 CHCRPGTMGPQCRECAPGY--WGLP---EQG-------CRRCQC--PGGRCDPHTGRC-N 2132
C C PGT+G C++CAPGY LP ++G C C C CDP+TG+C N
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 2133 CPPGLSGERCDTCSQQHQVPVPGG-------PVGHSIHCEVCDHCVVLLLDDLERAGALL 2185
C +G+ CD C+ + V G HS CV+ D LL
Sbjct: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLL 1481
Query: 2186 PAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQ 2245
+E SS + S +P G H + + GQ
Sbjct: 1482 G--YEGKHCERCSSSYYGNPQTPGGSCQKCDC---NPHGSVHGDCDR---------TSGQ 1527
Query: 2246 DARRLGGQAVGTRD-QASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMS--QTGHLGLA 2302
RLG + + + +L T+ + + + +D ++S TG + +
Sbjct: 1528 CVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVP 1587
Query: 2303 NASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAE-----LAAAQRLLA---RVQE 2354
+ E + L E LL E +DLG + AE R+LA +V
Sbjct: 1588 YGILSNLENTTKYLQ--ESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNR 1645
Query: 2355 QLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVD-----ATREAQELNSRNQERL 2409
+++E+Q LA +RL +M+ + LN+ +D Q + L
Sbjct: 1646 ATERIFKESQDLAIAI-ERLQMSITEIME-KTTLNQTLDEDFLLPNSTLQNMQQNGTSLL 1703
Query: 2410 EEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLL 2469
E R NATL+ L AA D L+ + + ++ LE L + A L
Sbjct: 1704 EIMQIRDFTQLHQNATLE--LKAAEDLLSQI------QENYQKPLEELEVLKEAASHVLS 1755
Query: 2470 QRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSR-- 2527
+ A + LV AEA Q+ L L +++ + + + +L E N S
Sbjct: 1756 KHNNELKAAEA---LVREAEAKMQESNHLLLMVNANLREFSDKKL--HVQEEQNLTSELI 1810
Query: 2528 -----ILQAVQAAEDAAGQALQQ-ADH-----TWATVVRQGLVD 2560
++ A A DA AL+ DH W+ +R + D
Sbjct: 1811 VQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDD 1854
Score = 47.4 bits (111), Expect = 3e-04
Identities = 44/175 (25%), Positives = 64/175 (36%), Gaps = 43/175 (24%)
Query: 719 YCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGF----WGL-SPSNPEGC 773
Y A SC P D + Q C C + G SC+RC PG+ W + S+ C
Sbjct: 273 YGHASSC------PWDETTKKLQ--CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTC 324
Query: 774 TRCSCDLRG--------------TLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFGL 818
C+C + +L + + G G C C + G C +C DG++
Sbjct: 325 EACNCHNKAKDCYYDESVAKQKKSLNTAGQFR-GGGVCINCLQNTMGINCETCIDGYYRP 383
Query: 819 DQADYF---GCRSCRCDIGGALGQSC-----------EPRTGVCRCRPNTQGPTC 859
+ + CR C CD G+L C + G C C+ G C
Sbjct: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKC 438
Score = 44.7 bits (104), Expect = 0.002
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQ 1497
CGC+ VG+ EP G C C +V G+ C RC G++ P C C ++
Sbjct: 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
Query: 1498 C 1498
C
Sbjct: 512 C 512
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 475 bits (1222), Expect = e-133
Identities = 395/1306 (30%), Positives = 540/1306 (41%), Gaps = 160/1306 (12%)
Query: 1457 CPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGARLCDELT----------- 1495
C C + G DC RC + P C PC+C R +E T
Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGR-SEECTFDRELFRSTGH 348
Query: 1496 -GQCI-CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCR 1553
G+C C T P C CQ + P + C+ C+C G L CD D+G C C+
Sbjct: 349 GGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQ---CD-DTGTCACK 404
Query: 1554 PNVTGRRCDTCSPGFHGYPR--CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCS 1611
P VTG +CD C PGFH CRPC C+ AG+ CDP +G+C CKENV+G CD+C
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 1612 LGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFV------DMEGWVLLSTDRQVVPH 1665
GTF+L NP GC+ CFC+G ++ C S++ + + EGW S P
Sbjct: 464 PGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPP 523
Query: 1666 ERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDV 1725
+ P +L PE EL AP +LGD+ SYG L L GD
Sbjct: 524 QWSPNGVLLS----------PEDEEEL--TAPEKFLGDQRFSYGQPLI--LTFRVPPGDS 569
Query: 1726 FVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSRE---- 1781
+P++ R L+G ++++ + P G + VE F ET V+
Sbjct: 570 PLPVQLR----LEGTGLALSLRHSSLSGPQDA--GHPREVELRFHLQETSEDVAPPLPPF 623
Query: 1782 ELMMVLASLEQLQIRALFSQISSA-VFLRRVALEVASPAGQGALASNVELCLCPASYRGD 1840
+LA+L L++R + VFL V L A P G AS VE+C CP Y G
Sbjct: 624 HFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARP-GLSPPASWVEICSCPTGYTGQ 682
Query: 1841 SCQECAPGFYRDV-KGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGF 1899
C+ CAPG+ R++ +G CVPC C+ H C P +G+CV C H+TEG CERC GF
Sbjct: 683 FCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGF 740
Query: 1900 VSSRDDPSAP-CVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKPGYAGASCERCAPGFFG 1957
+ A C CPCP E C C PG G CE C GFFG
Sbjct: 741 YGNPFAGQADDCQPCPCPGQSACTTIPES-----REVVCTHCPPGQRGRRCEVCDDGFFG 795
Query: 1958 NPLVLGSSCQPC---DCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNA 2014
+PL L QPC CSGN DPN + +CDPL+G C CL +TTG CE C GFYG+A
Sbjct: 796 DPLGLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSA 854
Query: 2015 LLP---GNCTRCDCTPCGTEA----CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGC 2067
L P C C C P G+ + CDP +G C C VT R C RC G F GC
Sbjct: 855 LAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGC 914
Query: 2068 RPCACGP-AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-PGGRCD 2125
R C C P ++ +CHP++GQC CRPG G C C G++G +GCR C+C P G
Sbjct: 915 RSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAAS 974
Query: 2126 PH---TGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAG 2182
G C C PG G +CD C + G HC+ C C L+ ++ +
Sbjct: 975 AQCHENGTCVCRPGFEGYKCDRCHDNFFLTADG------THCQQCPSCYALVKEEAAKLK 1028
Query: 2183 ALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTS 2242
A L L+G + S W L L PR + Q +L +
Sbjct: 1029 ARLTLTEGWLQGSDCGS-PWGPLDILLGE------------APRGDVYQGHHLLPGAREA 1075
Query: 2243 LGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLA 2302
+ L G R+Q +L G ++ + ++ L + H
Sbjct: 1076 FLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAI 1135
Query: 2303 NASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQ--LSSLW 2360
AS ++ + L E RA A + A + LLA L +L
Sbjct: 1136 LASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLL 1195
Query: 2361 EENQALATQT--RDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQE 2418
E AL TQ DR + +A LR A+ + E L Q+
Sbjct: 1196 EGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEA--------------ESVLATVQQ 1241
Query: 2419 LSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPA 2478
+ D A A L A+ L R L + LE+ AS T + +QT + A
Sbjct: 1242 VGADTAPYLALL-ASPGALPQKSRA-EDLGLKAKALEKTVASWQHMATEAARTLQTAAQA 1299
Query: 2479 GSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDA 2538
LR E Q+ + LTQ + A ++ A D
Sbjct: 1300 --TLRQTEPLTKLHQEA---------------RAALTQASSSVQAATVTVMGARTLLADL 1342
Query: 2539 AGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLR 2598
G LQ +++ + +LLA++ + Q ++ LG A L +
Sbjct: 1343 EGMKLQFPRPKDQAALQRKADSVSDRLLADT---RKKTKQAERMLGNA-APLSSS----- 1393
Query: 2599 DVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVE 2658
AKK EA + A + +K AH +A +Q AT Q+ Q +
Sbjct: 1394 ---AKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEAR 1450
Query: 2659 RWQGQYEGLRGQDLGQAVLDAGHSVSTLEK---TLPQLLAKLSILE 2701
R + + G L + S +LEK TL +LLA+L L+
Sbjct: 1451 RQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLD 1496
Score = 297 bits (760), Expect = 1e-79
Identities = 188/543 (34%), Positives = 255/543 (46%), Gaps = 82/543 (15%)
Query: 20 APLLLVGLALL-------GAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARG 72
A LL+GLALL G + AG P + N A G AS TCG
Sbjct: 3 AAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGS------ 56
Query: 73 SPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAID----GTERWW 128
P ED +C VG AG +C C AA+ + H AS D WW
Sbjct: 57 ---PPED-FCPHVGAAGAGA---------HCQRCDAADPQRHHNASYLTDFHSQDESTWW 103
Query: 129 QSPPLSRGLEY-NEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
QSP ++ G++Y VN+TL LG+ + + YV +KF S RP+ + + + ++P+QF
Sbjct: 104 QSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTS-RPESFAIYKRSRADGPWEPYQF 162
Query: 188 FASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYS 247
+++S + R Q L + A CT+E+S I PL G + S + GRP A NF S
Sbjct: 163 YSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEES 222
Query: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHAD 307
P L+E+ +T + + R NT + +DP V + YYY++ D S+GGRC C+GHA
Sbjct: 223 PGLQEWVTSTELLISLDRLNTFGDDIF----KDPKVLQSYYYAVSDFSVGGRCKCNGHAS 278
Query: 308 ACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATD 367
C P +L C CQHNT G C+RC P F +PW TA +A+EC CNC G + +
Sbjct: 279 ECG---PDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEE 335
Query: 368 CYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR-SPNHPLDSPHVC 426
C +D E+ R GG C C+ HT G +CERC FY P P C
Sbjct: 336 CTFDRELFRSTGH---------GGRCHHCRDHTAGPHCERCQENFYHWDPRMP------C 380
Query: 427 RRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVL 486
+ C+C+S + D TG C C+P +G +CD C GF P + N
Sbjct: 381 QPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN------- 433
Query: 487 PAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG------PGCQP 540
PAG + C DPR GRC CK N +G C+ C PG + GC
Sbjct: 434 PAGSLDTC--------------DPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
Query: 541 CQC 543
C C
Sbjct: 480 CFC 482
Score = 208 bits (529), Expect = 9e-53
Identities = 133/404 (32%), Positives = 166/404 (41%), Gaps = 64/404 (15%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
C+C G C+ C PG+ ++ P A+ C C C H T DP
Sbjct: 673 CSCPTGYTGQFCESCAPGYKRE--MPQGGPYAS-CVPCTCNQHGT---CDPNT------- 719
Query: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTC- 440
G+C+ C HHT G +CERCLPGFY +P C+ C C T
Sbjct: 720 ---------GICV-CSHHTEGPSCERCLPGFYGNPF--AGQADDCQPCPCPGQSACTTIP 767
Query: 441 EDLTGRC-YCRPNFSGERCDVCAEGFTGFP---SCYPTPSSSNDTREQVLPAGQIVNCDC 496
E C +C P G RC+VC +GF G P +P P C C
Sbjct: 768 ESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCH---------------QCQC 812
Query: 497 SAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG--------CQPCQCSSPG 547
S DP G CL C N G HCE C GFYG C PC C G
Sbjct: 813 SGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQG 872
Query: 548 VADDR--CDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGC-DE 601
++ CDP TGQC C C RC PG+F C+ C C P G+ + C +
Sbjct: 873 SVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPK 932
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGF--PNCQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
G+C C+P G CDRC+ G+ GF C+AC C P GA C G C CRPG+ G
Sbjct: 933 TGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGY 992
Query: 660 ACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVT 703
C C F F + HC S +A + + R +T
Sbjct: 993 KCDRCHDNF--FLTADGTHCQQCPSCYALVKEEAAKLKARLTLT 1034
Score = 207 bits (526), Expect = 2e-52
Identities = 119/346 (34%), Positives = 155/346 (44%), Gaps = 52/346 (15%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
C C+ H DP C C H+T G +C+RC PGF P+ A A++CQ C
Sbjct: 707 CTCNQHGTC-------DPNTGICVCSHHTEGPSCERCLPGFYGNPF----AGQADDCQPC 755
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
C G + C PE S+ + VC C G CE C GF+ P
Sbjct: 756 PCPGQSA-CTTIPE------SREV--------VCTHCPPGQRGRRCEVCDDGFFGDPLGL 800
Query: 420 LDSPHVCRRCNCESDFTD---GTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTP 475
P C +C C + G C+ L+G C C N +G+ C+ C EGF G
Sbjct: 801 FGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG-------- 852
Query: 476 SSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY- 534
S+ R PA + + C C G+ DP G+C C P+ C C PGF+
Sbjct: 853 -SALAPR----PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
Query: 535 ---GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL--CQLCGC 589
G GC+ C+C G +D+C P TGQC CR G G CDRC G+F F + C+ C C
Sbjct: 908 LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRC 967
Query: 590 SPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYH---GFPNCQAC 632
SP G C E G C+C+P F G CDRC + +CQ C
Sbjct: 968 SPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 200 bits (508), Expect = 2e-50
Identities = 122/338 (36%), Positives = 146/338 (43%), Gaps = 54/338 (15%)
Query: 560 CRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEF 611
C C G+ G C+ CAPGY + C C C+ GT CD G C+C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 612 AGPHCDRCRPGYHGFP------NCQACTCDPRGALDQLCGAGGLC--RCRPGYTGTACQE 663
GP C+RC PG++G P +CQ C C + A + + + C PG G C+
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Query: 664 CSPGFHGFP--------SCVPCHCSAEGSLHAA--CDPRSGQC-SCRPRVTGLRCDTCVP 712
C GF G P C C CS +A CDP SG C C TG C+ C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
Query: 713 GAYNFPY-------CEAGSCHPAGLA----PVDPALPEAQVPCMCRAHVEGPSCDRCKPG 761
G Y C SCHP G P DP + C C HV C RC PG
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQ----CSCLPHVTARDCSRCYPG 904
Query: 762 FWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQA 821
F+ L P GC C C G+ +C P TGQC C+P V GQAC C+ GFFG
Sbjct: 905 FFDLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF--- 957
Query: 822 DYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
GCR+CRC GA C G C CRP +G C
Sbjct: 958 SIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKC 994
Score = 194 bits (493), Expect = 1e-48
Identities = 132/391 (33%), Positives = 167/391 (42%), Gaps = 60/391 (15%)
Query: 515 CLCKPNFQGTHCELCAPGFY------GP--GCQPCQCSSPGVADDRCDPDTGQCRCRVGF 566
C C + G CE CAPG+ GP C PC C+ G CDP+TG C C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 567 EGATCDRCAPGYFHFPL------CQLCGC---SPAGTLPEGCDEAGRCLCQPEFAGPHCD 617
EG +C+RC PG++ P CQ C C S T+PE E C P G C+
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPES-REVVCTHCPPGQRGRRCE 787
Query: 618 RCRPGYHGFP--------NCQACTC----DPR--GALDQLCGAGGLCRCRPGYTGTACQE 663
C G+ G P C C C DP G D L +G RC TG C+
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPL--SGHCLRCLHNTTGDHCEH 845
Query: 664 CSPGFHGFP-------SCVPCHCSAEGSL--HAACDPRSGQCSCRPRVTGLRCDTCVPGA 714
C GF+G C+PC C +GS+ CDP +GQCSC P VT C C PG
Sbjct: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
Query: 715 YNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPE 771
++ C + CHP G + D P+ C CR V G +CDRC+ GF+G S +
Sbjct: 906 FDLQPGRGCRSCKCHPLG-SQEDQCHPKTG-QCTCRPGVTGQACDRCQLGFFGFSI---K 960
Query: 772 GCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
GC C C G A+C G C C+P G C C D FF AD C+ C
Sbjct: 961 GCRACRCSPLGAAS--AQCHEN-GTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQCPS 1015
Query: 832 DIGGALGQSCEPRTGVCRCRPNTQGPTCSEP 862
++ + + + QG C P
Sbjct: 1016 CYALVKEEAAKLKARLTLTEGWLQGSDCGSP 1046
Score = 177 bits (448), Expect = 2e-43
Identities = 116/356 (32%), Positives = 148/356 (41%), Gaps = 65/356 (18%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C ++G+ C+ CA G+ Q P V C C+ GT C
Sbjct: 673 CSCPTGYTGQFCESCAPGY-------------KREMPQGGPYASCVPCTCNQHGT----C 715
Query: 507 RKDPRVGRCLCKPNFQGTHCELCAPGFYG-------PGCQPCQCSSPGVADDRCDPDTGQ 559
DP G C+C + +G CE C PGFYG CQPC C PG + P++ +
Sbjct: 716 --DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC--PGQSACTTIPESRE 771
Query: 560 C---RCRVGFEGATCDRCAPGYFHFPL--------CQLCGCSPAGTLPEG----CDE-AG 603
C G G C+ C G+F PL C C CS G + CD +G
Sbjct: 772 VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGNCDPLSG 829
Query: 604 RCL-CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAG---GLCRC 652
CL C G HC+ C+ G++G C C+C P+G++ + G C C
Sbjct: 830 HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSC 889
Query: 653 RPGYTGTACQECSPGFHGFP---SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT 709
P T C C PGF C C C GS C P++GQC+CRP VTG CD
Sbjct: 890 LPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 949
Query: 710 CVPGAYNFPY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFW 763
C G + F C A C P G A A C+CR EG CDRC F+
Sbjct: 950 CQLGFFGFSIKGCRACRCSPLGAA---SAQCHENGTCVCRPGFEGYKCDRCHDNFF 1002
Score = 138 bits (348), Expect = 9e-32
Identities = 77/203 (37%), Positives = 93/203 (45%), Gaps = 18/203 (8%)
Query: 1933 GRTQCLCKPGYAGASCERCAPGFFGNPLVLGSS-----CQPCDCSGNGDPNLLFSDCDPL 1987
G+ C C+ G CERC P F P G++ C PC+CSG + +
Sbjct: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
Query: 1988 T---GACRGCLRHTTGPRCEICAPGFY-GNALLPGNCTRCDCTPCGT--EACDPHSGHCL 2041
T G C C HT GP CE C FY + +P C CDC G+ CD +G C
Sbjct: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCD-DTGTCA 402
Query: 2042 CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE 2101
CK VTG +CDRC G GGCRPC C PA C P+SG+C C+ G C
Sbjct: 403 CKPTVTGWKCDRCLPGFHSLSE-GGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDR 461
Query: 2102 CAPGYWGLPEQ---GCRRCQCPG 2121
C PG + L GC C C G
Sbjct: 462 CRPGTFNLQPHNPAGCSSCFCYG 484
Score = 136 bits (342), Expect = 4e-31
Identities = 88/284 (30%), Positives = 112/284 (39%), Gaps = 81/284 (28%)
Query: 649 LCRCRPGYTGTACQECSPGFH-------GFPSCVPCHCSAEGSLHAACDPRSGQCSCRPR 701
+C C GYTG C+ C+PG+ + SCVPC C+ H CDP +G C C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ----HGTCDPNTGICVCSHH 727
Query: 702 VTGLRCDTCVPGAYNFPYC-EAGSCHPAGLAPVDPA---LPEA-QVPCM-CRAHVEGPSC 755
G C+ C+PG Y P+ +A C P P A +PE+ +V C C G C
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCP-CPGQSACTTIPESREVVCTHCPPGQRGRRC 786
Query: 756 DRCKPGFWGLSP----SNPEGCTRCSCD---------------------LRGTLGGVAE- 789
+ C GF+G P +P+ C +C C L T G E
Sbjct: 787 EVCDDGFFG-DPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
Query: 790 ----------------------------------CQPGTGQCFCKPHVCGQACASCKDGF 815
C P TGQC C PHV + C+ C GF
Sbjct: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
Query: 816 FGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
F L GCRSC+C G+ C P+TG C CRP G C
Sbjct: 906 FDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC 947
Score = 135 bits (340), Expect = 7e-31
Identities = 77/207 (37%), Positives = 99/207 (47%), Gaps = 31/207 (14%)
Query: 598 GCDEAGR--CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA------ 639
G D AG+ C CQ G C+RC P + P C C C R
Sbjct: 281 GPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDR 340
Query: 640 -LDQLCGAGGLCR-CRPGYTGTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSG 694
L + G GG C CR G C+ C F+ + C PC C + GSLH CD +G
Sbjct: 341 ELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDD-TG 399
Query: 695 QCSCRPRVTGLRCDTCVPGAYNFPY--CEAGSCHPAG-LAPVDPALPEAQVPCMCRAHVE 751
C+C+P VTG +CD C+PG ++ C +C+PAG L DP C C+ +VE
Sbjct: 400 TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR----CPCKENVE 455
Query: 752 GPSCDRCKPGFWGLSPSNPEGCTRCSC 778
G CDRC+PG + L P NP GC+ C C
Sbjct: 456 GNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 131 bits (329), Expect = 1e-29
Identities = 82/229 (35%), Positives = 103/229 (44%), Gaps = 37/229 (16%)
Query: 1864 CQCHGHSDRCLP--GSGVCVDCQHNTEGAHCERCQAGF-----VSSRDDPSAPCVSCPCP 1916
C+C+GH+ C P + CQHNT G CERC F + + C+ C C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC- 329
Query: 1917 LSVPSNNFAEGCVL---------RGGRTQCLCKPGYAGASCERCAPGFF-GNPLVLGSSC 1966
+ +E C GGR C+ AG CERC F+ +P + C
Sbjct: 330 -----SGRSEECTFDRELFRSTGHGGRCH-HCRDHTAGPHCERCQENFYHWDPRM---PC 380
Query: 1967 QPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCT 2026
QPCDC G +L CD TG C C TG +C+ C PGF+ +L G C C C
Sbjct: 381 QPCDCQSAGSLHL---QCDD-TGTC-ACKPTVTGWKCDRCLPGFH--SLSEGGCRPCTCN 433
Query: 2027 PCGT-EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFD--GCGGCRPCAC 2072
P G+ + CDP SG C CK V G CDRC+ G F GC C C
Sbjct: 434 PAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 124 bits (311), Expect = 2e-27
Identities = 77/222 (34%), Positives = 97/222 (43%), Gaps = 36/222 (16%)
Query: 1437 PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP------NCRPCDC-GAR 1489
PC C++ G TC+P G C C H G C RC G++G P +C+PC C G
Sbjct: 706 PCTCNQHG----TCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQS 761
Query: 1490 LCDELTGQ----CI-CPPRTIPPDCLLCQPQTFG------CHPLVGCEECNCSGPGIQEL 1538
C + C CPP C +C FG HP C +C CSG +
Sbjct: 762 ACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHP-QPCHQCQCSG-NVDPN 819
Query: 1539 TDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHG-------YPRCRPCDCHEAGTAPG--V 1588
CD SG C +C N TG C+ C GF+G +C PC CH G+
Sbjct: 820 AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP 879
Query: 1589 CDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
CDP+TGQC C +V C +C G F L +GC C C
Sbjct: 880 CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG--RGCRSCKC 919
Score = 122 bits (307), Expect = 5e-27
Identities = 74/229 (32%), Positives = 93/229 (40%), Gaps = 42/229 (18%)
Query: 494 CDCSAAGTQGNACRKDPRVG---RCLCKPNFQGTHCELCAPGFY-----------GPGCQ 539
C C+ G+A P V C C+ N GT CE C P F C
Sbjct: 271 CKCN-----GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECL 325
Query: 540 PCQCSSPGVADDRCDPDT---------GQCR-CRVGFEGATCDRCAPGYFHFPL---CQL 586
PC CS + C D G+C CR G C+RC ++H+ CQ
Sbjct: 326 PCNCSG---RSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQP 382
Query: 587 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFP--NCQACTCDPRGALDQLC 644
C C AG+L CD+ G C C+P G CDRC PG+H C+ CTC+P G+LD
Sbjct: 383 CDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
Query: 645 GAGGLCRCRPGYTGTACQECSPGF-----HGFPSCVPCHCSAEGSLHAA 688
G C C+ G C C PG H C C C + A+
Sbjct: 443 PRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCAS 491
Score = 106 bits (264), Expect = 5e-22
Identities = 72/213 (33%), Positives = 92/213 (43%), Gaps = 35/213 (16%)
Query: 644 CG---AGGL-CRCRPGYTGTACQECSPGFHGFP----------SCVPCHCSAEGSLHAAC 689
CG AG L CRC+ TGT C+ C P F P C+PC+CS S
Sbjct: 280 CGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGR-SEECTF 338
Query: 690 DPR-------SGQCS-CRPRVTGLRCDTCVPGAYNFPY---CEAGSCHPAGLAPVDPALP 738
D G+C CR G C+ C Y++ C+ C AG +
Sbjct: 339 DRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQC--- 395
Query: 739 EAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF 798
+ C C+ V G CDRC PGF LS GC C+C+ G+L C P +G+C
Sbjct: 396 DDTGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSLD---TCDPRSGRCP 449
Query: 799 CKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
CK +V G C C+ G F L + GC SC C
Sbjct: 450 CKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 95.5 bits (236), Expect = 9e-19
Identities = 54/142 (38%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 1437 PCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWGFP---NCRPCDC---GA 1488
PC CH G+ C+P GQC C HV RDCSRC G++ CR C C G+
Sbjct: 865 PCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGS 924
Query: 1489 R--LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTD 1546
+ C TGQC C P C CQ FG + GC C CS G C +
Sbjct: 925 QEDQCHPKTGQCTCRPGVTGQACDRCQLGFFG-FSIKGCRACRCSPLG---AASAQCH-E 979
Query: 1547 SGQCKCRPNVTGRRCDTCSPGF 1568
+G C CRP G +CD C F
Sbjct: 980 NGTCVCRPGFEGYKCDRCHDNF 1001
Score = 67.0 bits (162), Expect = 3e-10
Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 1434 GARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF--PNCRPCDC----- 1486
G R C CH +G+ C P GQC C V G+ C RC G++GF CR C C
Sbjct: 913 GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA 972
Query: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEEC 1528
+ C E G C+C P C C F C++C
Sbjct: 973 ASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 63.5 bits (153), Expect = 4e-09
Identities = 35/105 (33%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Query: 1436 RPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP--NCRPCDCGAR---- 1489
+PC C G+ C+ G C C V G C RC G+ CRPC C
Sbjct: 381 QPCDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD 439
Query: 1490 LCDELTGQCICPPRTIPPDCLLCQPQTFGCHP--LVGCEECNCSG 1532
CD +G+C C C C+P TF P GC C C G
Sbjct: 440 TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484
Score = 56.6 bits (135), Expect = 4e-07
Identities = 38/97 (39%), Positives = 44/97 (45%), Gaps = 21/97 (21%)
Query: 281 PTVTR----RYYYSIKDISIGG--RCVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGT 332
PTVT R +S GG C C+ G D CD + +C C+ N G
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG------RCPCKENVEGNL 458
Query: 333 CDRCCPG-FNQQPWKPATANSANECQSCNCYGHATDC 368
CDRC PG FN QP PA C SC CYGH+ C
Sbjct: 459 CDRCRPGTFNLQPHNPAG------CSSCFCYGHSKVC 489
Score = 52.8 bits (125), Expect = 6e-06
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Query: 1413 PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCA 1472
P+ + C G RPC C+ G+ TC+P G+CPC +V G C RC
Sbjct: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
Query: 1473 TGYWGFPNCRPCDCGARLC 1491
G + P C + C
Sbjct: 464 PGTFNLQPHNPAGCSSCFC 482
Score = 32.7 bits (73), Expect = 6.8
Identities = 22/85 (25%), Positives = 30/85 (35%), Gaps = 5/85 (5%)
Query: 1413 PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCA 1472
P + C F G R C C +GA C G C C G C RC
Sbjct: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCH 998
Query: 1473 TGYW---GFPNCRPC-DCGARLCDE 1493
++ +C+ C C A + +E
Sbjct: 999 DNFFLTADGTHCQQCPSCYALVKEE 1023
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 469 bits (1207), Expect = e-131
Identities = 275/781 (35%), Positives = 377/781 (48%), Gaps = 77/781 (9%)
Query: 1456 QCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGARL----CDELT------ 1495
+C C + G C +C G+ P C C+C + DE
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 1496 ----------GQCI-CPPRTIPPDCLLCQPQTF---GCHPLVG--CEECNCSGPGIQELT 1539
G CI C T +C C F G P C+ C+C G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGS---L 422
Query: 1540 DPTCDTDS---------GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCD 1590
+ C D G C C+ G CD C+ G+ GYP C+ C+C G+ D
Sbjct: 423 NEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--D 480
Query: 1591 PLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDM 1650
P G C CKENV+G C +C G F+L N KGC CFC G + RC+SS +T + DM
Sbjct: 481 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM 540
Query: 1651 EGWVLLSTDRQVVPHERQP---GTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSS 1707
GW L ++ +Q + + +A+P ++ YW AP YLG+++ +
Sbjct: 541 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSY---YWSAPAPYLGNKLPA 597
Query: 1708 YGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMSI-TFLEPAYPTPGHVHRGQLQLVE 1766
GG L + + + + + + ++L+GN +SI T + Y P H L L E
Sbjct: 598 VGGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKE 657
Query: 1767 GNFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVF-LRRVALEVA-SPAGQGAL 1824
+F T V R+E M VLA+L+++ ++ +S A+F L V LE A S G++
Sbjct: 658 ESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSI 717
Query: 1825 ASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQ 1884
A+ VE+C CP Y G SC+ C P R +F G C PCQC GH++ C +G C++C+
Sbjct: 718 AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCK 777
Query: 1885 HNTEGAHCERCQAGFVSS-RDDPSAPCVSCPCPLSVPSNNFAEGCVLRG--GRTQCLCKP 1941
+T G +C++C GF S C C CPL++PSNNF+ C L G C
Sbjct: 778 DHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPV 837
Query: 1942 GYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGP 2001
GY G CERCA G+FG P V G SCQPC C+ N D ++ S CD L+G+C C TTG
Sbjct: 838 GYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGR 896
Query: 2002 RCEICAPGFYGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRCQEGHF 2059
CE+CA G++G+A+ NC C C G+ E C +G C C+A V G+RCD+C+ G F
Sbjct: 897 YCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTF 956
Query: 2060 GFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC 2119
G GC PC C S +SGQC C+PG G +C CA GY+ E GC C+C
Sbjct: 957 GLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 2120 P--GGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSI--HCEVCDHCVVLLL 2175
G CDP TGRC CPP GE+C C+ GHSI C+ C+ V L
Sbjct: 1017 SHLGNNCDPKTGRCICPPNTIGEKCSKCAP--------NTWGHSITTGCKACNCSTVGSL 1068
Query: 2176 D 2176
D
Sbjct: 1069 D 1069
Score = 440 bits (1131), Expect = e-122
Identities = 241/574 (41%), Positives = 314/574 (54%), Gaps = 84/574 (14%)
Query: 15 GPRGPAPLLLVGLALLGAARAR------EEAGGGFSLHPPYFNLAEGARIAASATCGEEA 68
G G LLL+ L G R +A L P NLA A I +ATCGE+
Sbjct: 3 GAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKG 62
Query: 69 PARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICT--AANSNKAHPASNAIDGTER 126
P ++YCKLV P Q +R C IC ++N N+ HP +NAIDG
Sbjct: 63 P---------EMYCKLVEHV-----PGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNT 108
Query: 127 WWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQ 186
WWQSP + G+EY+ V +TLDL QVF +AYV++K ANSPRP W+LERS+D Y+PWQ
Sbjct: 109 WWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQ 167
Query: 187 FFASSKRDCLE------RFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG 240
+ A + +CL R GP + +DD ICT+ YS+I PLENGEI +SL+NGRP
Sbjct: 168 YHAVTDTECLTLYNIYPRTGPPSY---AKDDEVICTSFYSKIHPLENGEIHISLINGRPS 224
Query: 241 AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT-----VTRRYYYSIKDIS 295
A + SP L EFT A +RLRF R TL LM A +DP VTRRYYYS+KDIS
Sbjct: 225 ADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDIS 282
Query: 296 IGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANE 355
+GG C+C+GHA AC T+ R C C+HNTCG +CD+CCPGF+Q+PW+ T + E
Sbjct: 283 VGGMCICYGHARACPLDPATNKSR--CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTE 340
Query: 356 CQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRS 415
C++CNC+G A +CYYD V RR S ++ G Y GGGVCI+C +T G+NCE C GF+R
Sbjct: 341 CEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400
Query: 416 PNHPLDSPHVCRRCNCE--SDFTDGTCED--------LTGRCYCRPNFSGERCDVCAEGF 465
+ P C+ C+C+ + +D G C+C+ F G CD CA G+
Sbjct: 401 KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Query: 466 TGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTH 525
TG+P C C+CS G++ +DP G C+CK N +G
Sbjct: 461 TGYPDCKA--------------------CNCSGLGSK----NEDPCFGPCICKENVEGGD 496
Query: 526 CELCAPGFYG------PGCQPCQCSSPGVADDRC 553
C C GF+ GC C CS +RC
Sbjct: 497 CSRCKSGFFNLQEDNWKGCDECFCSG---VSNRC 527
Score = 394 bits (1011), Expect = e-108
Identities = 225/634 (35%), Positives = 303/634 (47%), Gaps = 77/634 (12%)
Query: 1424 AASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN--C 1481
A + L G PC C+ G+ CE GQC C V G+ C RCA GY+ F C
Sbjct: 953 AGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGC 1011
Query: 1482 RPCDCG--ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELT 1539
C+C CD TG+CICPP TI C C P T+G GC+ CNCS G
Sbjct: 1012 TACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS---L 1068
Query: 1540 DPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDP-------- 1591
D C+ ++GQC C P +G +C CS G YPRC CDC GT CD
Sbjct: 1069 DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCS 1128
Query: 1592 -LTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDM 1650
TGQC CK NV+G CD+C G F LDA NP GC+ C+CFG T +C + +
Sbjct: 1129 DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGL------I 1182
Query: 1651 EGWVLLSTDRQVVP-------HERQPGT-----------EMLRADLRHVPEAVPEAFPEL 1692
WV L ++ ++P H G +++R DL P
Sbjct: 1183 RTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEP---------F 1233
Query: 1693 YWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMS---ITFLEP 1749
YW+ P + G ++ +YGG L+Y ++ E + F P V+++G + I
Sbjct: 1234 YWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYN--PQVIIRGGTPTHARIIVRHM 1291
Query: 1750 AYPTPGHVHRGQLQLVEGNFRH----TETRNTVSREELMMVLASLEQLQIRALFSQISSA 1805
A P G + R ++++ E +++ TV+RE+ + +L + + I+A +
Sbjct: 1292 AAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQ 1351
Query: 1806 VFLRRVALEVASPAGQGAL----ASNVELCLCPASYRGDSCQECAPGFYR-------DVK 1854
+ +++EVA G+G A +E C CP Y G SC+ C PGFYR
Sbjct: 1352 SRISEISMEVAEQ-GRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTP 1410
Query: 1855 GLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCP 1914
G LG CVPCQC+GHS C P + +C +CQH+T G CERC G+ C C
Sbjct: 1411 GPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCA 1470
Query: 1915 CPLSVPSNNFAEGCVLRG-GRTQC-LCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCS 1972
CPL SNNF+ CV G +C C GY G CERCAPG+ G+P G SCQ C+C
Sbjct: 1471 CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD 1530
Query: 1973 GNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
G L CDP+TG C C TG +C+ C
Sbjct: 1531 PYGS---LPVPCDPVTGFCT-CRPGATGRKCDGC 1560
Score = 347 bits (890), Expect = 1e-94
Identities = 440/1899 (23%), Positives = 741/1899 (39%), Gaps = 300/1899 (15%)
Query: 1936 QCLCKPGYAGASCERCAPGFFG--------NPLVLGSSCQPCDCSGNGDPNLLFSDCDPL 1987
+C C GY+G SCE C PGF+ P +C PC C+G+ S CDP
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHS------SLCDPE 1432
Query: 1988 TGACRGCLRHTTGPRCEICAPGFYGNAL-LPGNCTRCDC----------TPCGTEACDPH 2036
T C+ C HT G CE CA G+YG LP +C +C C C E D +
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 2037 SGHC-LCKAGVTGRRCDRCQEGHFGFDG--CGGCRPCACGP-AAEGSECHPQSGQCHCRP 2092
C C G G+ C+RC G+ G G G C+ C C P + C P +G C CRP
Sbjct: 1493 --RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRP 1550
Query: 2093 GTMGPQCRECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVP 2152
G G +C C +W E G C C
Sbjct: 1551 GATGRKCDGCK--HWHARE---------------------------GWECVFCG------ 1575
Query: 2153 VPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASI 2212
D C LLL DL R + + + IN + A +++ +
Sbjct: 1576 ---------------DECTGLLLGDLAR-------LEQMVMSINLTGPLPAP-YKMLYGL 1612
Query: 2213 ADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATL 2272
++ +L+ L P+ + +++ E +L + L +A Q E T
Sbjct: 1613 ENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTN 1672
Query: 2273 GHAKTLLAAIRAVDRTLSELMSQTGHLG--LANASAPSGEQLLRTLAEVERLLWEMRARD 2330
AK+L I+ + R + + L L L E+++++ E+R ++
Sbjct: 1673 TRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKN 1732
Query: 2331 LGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNR 2390
L + AE EL AA+ LL +V++ EN+ + R++LA ++ + D + L
Sbjct: 1733 LETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLRE 1792
Query: 2391 AVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQA 2450
A D REA L + NQ+ + ++K+ + ++ TL D L RL ++
Sbjct: 1793 ATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSI 1852
Query: 2451 KEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVE---AAEAHAQQLGQLALNLSSIIL 2507
+ +E + L L ++ S +L E AE+HA QL + L I+
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILD 1912
Query: 2508 DVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHT--WATVVR-------QGL 2558
+ ++ A A AYS I + AE A +A A AT R +G
Sbjct: 1913 EAK--NISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGC 1970
Query: 2559 VDRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAML 2618
+ ++ ++L + L + + + L G +T++ + A+ L + L
Sbjct: 1971 LQKSFRILNEAKKLANDVKENEDH-------LNGLKTRIENADARNGDLLRTLNDTLGKL 2023
Query: 2619 AMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGL----------- 2667
+ ++T+ K+ K A +A DTA V +Q+ + +N++ + Y L
Sbjct: 2024 SAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVV 2083
Query: 2668 RGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASIGRVRELIAQAR 2727
+ + + DA +V LE+ +L+ KL + + L +I ++ELI QAR
Sbjct: 2084 KDPSKNKIIADADATVKNLEQEADRLIDKL-----KPIKELEDNLKKNISEIKELINQAR 2138
Query: 2728 GAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPGQGTEDRFVMYMGS 2787
A+ +KV + G +RT + +Y + ++ D + Y+GS
Sbjct: 2139 KQANSIKVSVSSGGDC---IRTYKPEIKKGSYNNIVVNVK-------TAVADNLLFYLGS 2188
Query: 2788 RQATGDYMGVSLRDKKVHWVYQLGEAGPAV----LSIDEDIGEQFAAVSLDRTLQFGHMS 2843
+ D++ + +R KV +++ +G V L+ID+ + A RT + G +S
Sbjct: 2189 AKFI-DFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVA---SRTGRNGTIS 2244
Query: 2844 VTV----ERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGC 2899
V + ++ T T PG +L++ + +F VGG +R + GC
Sbjct: 2245 VRALDGPKASIVPSTHHSTSPPGYT-ILDVDANAMLF-VGGLTGKLKKADAVRVITFTGC 2302
Query: 2900 IEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGS-YLDGTGFARIS--- 2955
+ + + + L+NF R + D + C S D ++G+ DG G+A +S
Sbjct: 2303 MGETYFDNKPIGLWNF-REKEGDC---KGCTVSPQVED---SEGTIQFDGEGYALVSRPI 2355
Query: 2956 -FDSQISTTKRFEQELRLVSYSGVLFFL--KQQSQFLCLAVQEGSLVLLYDFGAGLKKAV 3012
+ IST + R S S +L +L + F+ + + +G + + YD G+G+ V
Sbjct: 2356 RWYPNISTVM---FKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVV 2412
Query: 3013 PLQPPPPLTSASKAIQVFLLGGSRKRVLVRV-------ERATVYSVEQDN---DLELADA 3062
Q + F L +K+ + + E S +N DL+ D
Sbjct: 2413 SNQ-----NHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDK 2467
Query: 3063 YYLGGVPPDQLPPSLRRLFPTGG--SVRGCVKGIK-ALGKYVDLKRLNTTGVSAGCTADL 3119
Y GG+ P+LR L P GC+K I+ + Y L + GV+ GC+ +
Sbjct: 2468 IYFGGL------PTLRNLRPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLEN 2521
Query: 3120 LVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYY-------------RA 3166
+ ++F GF+ L + P+ F + +S ++ R
Sbjct: 2522 VY--TVSFPKPGFVEL---SPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ 2576
Query: 3167 SPDGLCQVSLQQGRVSLQLLRTEVKTQAG---------FADGAPHYVAFYSNATGVWLYV 3217
+ + L +GR+ + L T +T F DG H V + V
Sbjct: 2577 TGQAYYVILLNRGRLEVH-LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQV 2635
Query: 3218 DDQLQQMKPHR-------------GPPPELQPQPEGPPRLLLGGLPESGTIYNFSGCISN 3264
D+ + M+ G PPE QP P L +P F GCI N
Sbjct: 2636 DENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSP-------LRNIPP------FEGCIWN 2682
Query: 3265 VFVQRLLGPQRVFDLQQNLGSVNVSTG-CA-PALQAQTPGLGPRGL----QATARKASRR 3318
+ + + D + + N G CA L+ G P + + A
Sbjct: 2683 LVINSV-----PMDFARPVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPT 2737
Query: 3319 SRQPARHPACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGL 3378
H C S QFG S +SH+ + +N ++ + V + GL
Sbjct: 2738 PTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGL 2797
Query: 3379 LLFTAR----------LRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKV 3428
L + AR LR G P + L +G + G+WHK+
Sbjct: 2798 LFYMARINHADFATVQLRNGLPYFSYDLGSGD-----------THTMIPTKINDGQWHKI 2846
Query: 3429 SVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSKL-PVTVGF 3487
+ K +L DGA + L+VGGLP + + ++ PVT
Sbjct: 2847 KIMRSKQEGILYVDGA----SNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSI 2902
Query: 3488 SGCVKRLRLHGRP--LGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGL 3545
GCV+ L + P L PT V C + G +F G+G + L D+ +
Sbjct: 2903 DGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDGTGFAKAVGGFKVGL-DLLV 2960
Query: 3546 ELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFST--SVTRPSVLCDG 3603
E E R TG++ + + + +++ +++++ D+GAG F+ P LCDG
Sbjct: 2961 EFEFRTTTTTGVLLGISSQKMDG-MGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDG 3019
Query: 3604 QWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAA-AAGAPAPLYLGGLPEPMAVQPWPPA-- 3660
QWH++ K + + L VD P A+ +A P+++GG P+ + +
Sbjct: 3020 QWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIP 3079
Query: 3661 YCGCMRRLAVNRS-----PVAMTRSVEVHGAVGASGCPA 3694
+ GC+R L + + V +++E+ G S CPA
Sbjct: 3080 FRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS-CPA 3117
Score = 276 bits (707), Expect = 2e-73
Identities = 160/509 (31%), Positives = 216/509 (42%), Gaps = 87/509 (17%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
C C G +C+ C P + C+ C C+GHA C
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD------------ 767
Query: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCE 441
D T G C++C+ HT G C++CLPGFY P C+ C C +
Sbjct: 768 --DVT----GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSN--- 816
Query: 442 DLTGRCY-----------CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQ 490
+ + C+ C ++G RC+ CAEG+ G PS +P G
Sbjct: 817 NFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS---------------VPGGS 861
Query: 491 IVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG-----CQPCQCS 544
C C+ D G CL CKP G +CELCA G++G CQPC+C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCN 921
Query: 545 SPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDE 601
+ G + C TGQC CR +G CD+C G F C C C+ G+ C+E
Sbjct: 922 AGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE 981
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGFPN--CQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
+G+C CQP G CDRC GY F C AC C G + G C C P G
Sbjct: 982 SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG--NNCDPKTGRCICPPNTIGE 1039
Query: 660 ACQECSPGFHGFP---SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYN 716
C +C+P G C C+CS GSL C+ +GQC+C P+ +G +C C G +N
Sbjct: 1040 KCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWN 1099
Query: 717 FPYCEAGSCHPAGLAPVDPALPEAQV----------PCMCRAHVEGPSCDRCKPGFWGLS 766
+P C C G D +++ C C+ +VEG CDRC+PG +GL
Sbjct: 1100 YPRCNLCDCFLPG---TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLD 1156
Query: 767 PSNPEGCTRCSCDLRGTLGGVAECQPGTG 795
NP GC+ C C G +C G
Sbjct: 1157 AKNPLGCSSCYC-----FGTTTQCSEAKG 1180
Score = 261 bits (666), Expect = 1e-68
Identities = 150/439 (34%), Positives = 208/439 (47%), Gaps = 65/439 (14%)
Query: 300 CVCHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C C GHA++CD D T +C C+ +T G CD+C PGF +P T ++ +CQ
Sbjct: 757 CQCFGHAESCD--DVTG----ECLNCKDHTGGPYCDKCLPGFYGEP----TKGTSEDCQP 806
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C + + P R+ G +C C TG CERC G++ P+
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSL---------GLICDGCPVGYTGPRCERCAEGYFGQPSV 857
Query: 419 PLDSPHVCRRCNCESDFT-DGTCEDLTGRC-YCRPNFSGERCDVCAEGFTGFPSCYPTPS 476
P S C +CN DF+ G+C+ L+G C C+P +G C++CA+G+ G
Sbjct: 858 PGGSCQPC-QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFG--------- 907
Query: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG- 535
+ A C C+A G+ C + G+C C+ N QG C+ C G +G
Sbjct: 908 -------DAVDAKNCQPCRCNAGGSFSEVCHS--QTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 536 ---PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL--CQLCGCS 590
GC PC C+S G C+ ++GQC C+ G G CDRCA GYF+F C C CS
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECS 1017
Query: 591 PAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRP---GYHGFPNCQACTCDPRGALDQLCGA 646
G CD + GRC+C P G C +C P G+ C+AC C G+LD C
Sbjct: 1018 HLG---NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNV 1074
Query: 647 G-GLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACD---------PRSGQC 696
G C C P ++G C ECS G +P C C C G+ CD ++GQC
Sbjct: 1075 NTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQC 1134
Query: 697 SCRPRVTGLRCDTCVPGAY 715
+C+ V G+ CD C PG +
Sbjct: 1135 TCKVNVEGIHCDRCRPGKF 1153
Score = 239 bits (610), Expect = 4e-62
Identities = 158/491 (32%), Positives = 204/491 (41%), Gaps = 71/491 (14%)
Query: 380 SQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT 439
S DG+ C TG +CE C P +R N + +C C C +
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPR-HRRVNGTIFGG-ICEPCQCFGHAE--S 765
Query: 440 CEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSA 498
C+D+TG C C+ + G CD C GF G PT +S D + C C
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYG----EPTKGTSEDCQP----------CACPL 811
Query: 499 AGTQGN---ACRKDPRVGRCL--CKPNFQGTHCELCAPGFYG----PG--CQPCQC---- 543
N C D +G C + G CE CA G++G PG CQPCQC
Sbjct: 812 NIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNL 871
Query: 544 --SSPGVADDRCDPDTGQCR-CRVGFEGATCDRCAPGYFHFPL----CQLCGCSPAGTLP 596
S PG CD +G C C+ G G C+ CA GYF + CQ C C+ G+
Sbjct: 872 DFSIPG----SCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFS 927
Query: 597 EGC-DEAGRCLCQPEFAGPHCDRCRPGYHGFPN---CQACTCDPRGALDQLCGAGGLCRC 652
E C + G+C C+ G CD+C+ G G + C C C+ G+ C G C C
Sbjct: 928 EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWC 987
Query: 653 RPGYTGTACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC 710
+PG TG C C+ G+ F C C CS G+ CDP++G+C C P G +C C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN---NCDPKTGRCICPPNTIGEKCSKC 1044
Query: 711 VPGAYNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSP 767
P + C+A +C G + Q C C G C C G W
Sbjct: 1045 APNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ--CNCHPKFSGAKCTECSRGHW---- 1098
Query: 768 SNPEGCTRCSCDLRGTLGGVAE-------CQPGTGQCFCKPHVCGQACASCKDGFFGLDQ 820
N C C C L GT + C TGQC CK +V G C C+ G FGLD
Sbjct: 1099 -NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA 1157
Query: 821 ADYFGCRSCRC 831
+ GC SC C
Sbjct: 1158 KNPLGCSSCYC 1168
Score = 234 bits (598), Expect = 9e-61
Identities = 157/464 (33%), Positives = 201/464 (43%), Gaps = 80/464 (17%)
Query: 436 TDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCD 495
TDG+ C C P ++G C+ SC+P N T + G C
Sbjct: 713 TDGSIAAAVEVCQCPPGYTGSSCE----------SCWPRHRRVNGT----IFGGICEPCQ 758
Query: 496 CSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGP-------GCQPCQCS--- 544
C G+A D G CL CK + G +C+ C PGFYG CQPC C
Sbjct: 759 CF-----GHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 545 -----SPGVADDR-----CDPDTGQCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGC 589
SP DR CD C VG+ G C+RCA GYF P CQ C C
Sbjct: 814 PSNNFSPTCHLDRSLGLICDG------CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQC 867
Query: 590 SPA--GTLPEGCDE-AGRCL-CQPEFAGPHCDRCRPGYHG----FPNCQACTCDPRGALD 641
+ ++P CD +G CL C+P G +C+ C GY G NCQ C C+ G+
Sbjct: 868 NDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFS 927
Query: 642 QLCGAG-GLCRCRPGYTGTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCS 697
++C + G C CR G C +C G G S CVPC+C++ GS C+ SGQC
Sbjct: 928 EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW 986
Query: 698 CRPRVTGLRCDTCVPGAYNFPY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC 755
C+P VTG +CD C G +NF C A C G DP C+C + G C
Sbjct: 987 CQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG-NNCDPKTGR----CICPPNTIGEKC 1041
Query: 756 DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGF 815
+C P WG S + GC C+C G+L +C TGQC C P G C C G
Sbjct: 1042 SKCAPNTWGHSITT--GCKACNCSTVGSLD--FQCNVNTGQCNCHPKFSGAKCTECSRGH 1097
Query: 816 FGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
+ +Y C C C + G +C+ T C C T TC
Sbjct: 1098 W-----NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTC 1136
Score = 226 bits (577), Expect = 2e-58
Identities = 130/394 (32%), Positives = 173/394 (43%), Gaps = 60/394 (15%)
Query: 515 CLCKPNFQGTHCELCAPG-------FYGPGCQPCQCSSPGVADDRCDPDTGQC-RCRVGF 566
C C P + G+ CE C P +G C+PCQC + CD TG+C C+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHA---ESCDDVTGECLNCKDHT 780
Query: 567 EGATCDRCAPGYFHFPL------CQLCGCS---PAGTLPEGCDEAGRCL------CQPEF 611
G CD+C PG++ P CQ C C P+ C R L C +
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTC-HLDRSLGLICDGCPVGY 839
Query: 612 AGPHCDRCRPGYHGFPN-----CQACTCDPR------GALDQLCGAGGLCRCRPGYTGTA 660
GP C+RC GY G P+ CQ C C+ G+ D L +G C+PG TG
Sbjct: 840 TGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSL--SGSCLICKPGTTGRY 897
Query: 661 CQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYN 716
C+ C+ G+ G +C PC C+A GS C ++GQC CR V G RCD C G +
Sbjct: 898 CELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFG 957
Query: 717 FPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGC 773
C +C+ G D E C C+ V G CDRC G++ GC
Sbjct: 958 LQSARGCVPCNCNSFGSKSFDC---EESGQCWCQPGVTGKKCDRCAHGYFNFQEG---GC 1011
Query: 774 TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI 833
T C C G C P TG+C C P+ G+ C+ C +G + GC++C C
Sbjct: 1012 TACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNCST 1064
Query: 834 GGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
G+L C TG C C P G C+E +R H+
Sbjct: 1065 VGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 167 bits (422), Expect = 2e-40
Identities = 119/414 (28%), Positives = 171/414 (41%), Gaps = 88/414 (21%)
Query: 1833 CPASYRGDSCQECAPGFYRD--VKGLFLGRCVPCQCHGHSDRCLPGS-----GVCVDCQH 1885
CP Y G C+ CA G++ V G G C PCQC+ + D +PGS G C+ C+
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPG---GSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP 891
Query: 1886 NTEGAHCERCQAGFVSSRDDPS--APCV----------------SCPCPLSVPSNNF--- 1924
T G +CE C G+ D PC C C +V
Sbjct: 892 GTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951
Query: 1925 ---------AEGCV-----LRGGRT-------QCLCKPGYAGASCERCAPGFFGNPLVLG 1963
A GCV G ++ QC C+PG G C+RCA G+F
Sbjct: 952 KAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFN---FQE 1008
Query: 1964 SSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRC 2023
C C+CS G+ +CDP TG C C +T G +C CAP +G+++ G C C
Sbjct: 1009 GGCTACECSHLGN------NCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITTG-CKAC 1060
Query: 2024 DCTPCGTE--ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCR-------PCACGP 2074
+C+ G+ C+ ++G C C +G +C C GH+ + C C C
Sbjct: 1061 NCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDS 1120
Query: 2075 AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRRCQCPGGRCDPHTGRC 2131
+ C Q+GQC C+ G C C PG +GL + GC C C G T +C
Sbjct: 1121 ETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFG-----TTTQC 1175
Query: 2132 NCPPGLSGERCDTCSQQHQVPVPGGPVGHSI-------HCEVCDHCVVLLLDDL 2178
+ GL ++Q +P+ + H+ H E+ H + L+ +DL
Sbjct: 1176 SEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAH-MDLMREDL 1228
Score = 136 bits (343), Expect = 3e-31
Identities = 80/242 (33%), Positives = 107/242 (44%), Gaps = 31/242 (12%)
Query: 643 LCGAGGLCRCRPGYTGTACQECSPG--------FHGFPSCVPCHCSAEGSLHAACDPRSG 694
+ A +C+C PGYTG++C+ C P F G C PC C +CD +G
Sbjct: 717 IAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGI--CEPCQCFGHAE---SCDDVTG 771
Query: 695 QC-SCRPRVTGLRCDTCVPGAYNFPYCEAGS-CHPAGLAPVDPALPEAQVPCM------- 745
+C +C+ G CD C+PG Y P C P P++ C
Sbjct: 772 ECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCA-CPLNIPSNNFSPTCHLDRSLGL 830
Query: 746 ----CRAHVEGPSCDRCKPGFWGLSPSNPEG-CTRCSCDLRGTLGGVAECQPGTGQCF-C 799
C GP C+RC G++G PS P G C C C+ C +G C C
Sbjct: 831 ICDGCPVGYTGPRCERCAEGYFG-QPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 800 KPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
KP G+ C C DG+FG D D C+ CRC+ GG+ + C +TG C CR N QG C
Sbjct: 890 KPGTTGRYCELCADGYFG-DAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 860 SE 861
+
Sbjct: 949 DK 950
Score = 117 bits (293), Expect = 2e-25
Identities = 85/269 (31%), Positives = 112/269 (41%), Gaps = 67/269 (24%)
Query: 1825 ASNVELCLCPASYRGDSCQECAPGFYRDV--KGLFLGR--CVPCQCHGHSDRC------- 1873
A+N C C + GDSC +C PGF++ G FL + C C CHG ++ C
Sbjct: 301 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA 360
Query: 1874 -----------LPGSGVCVDCQHNTEGAHCERCQAGFVSSR---DDPSAPCVSCPCPLSV 1919
G GVC++C NT G +CE C GF + + PC C C
Sbjct: 361 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCD--- 417
Query: 1920 PSNNFAEGCV-----LRGGRT--QCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCS 1972
P + E CV R G C CK G+ G SC+RCA G+ G P C+ C+CS
Sbjct: 418 PIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP-----DCKACNCS 472
Query: 1973 GNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA 2032
G G N DP G C C + G C C GF+ L N CD
Sbjct: 473 GLGSKNE-----DPCFGPCI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCD-------- 516
Query: 2033 CDPHSGHCLCKAGVTGRRCDRCQEGHFGF 2061
C C +GV+ +RCQ ++ +
Sbjct: 517 ------ECFC-SGVS----NRCQSSYWTY 534
Score = 116 bits (290), Expect = 5e-25
Identities = 67/219 (30%), Positives = 88/219 (40%), Gaps = 48/219 (21%)
Query: 604 RCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA-------------- 639
RC C+ G CD+C PG+H P C+AC C +
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 640 ---LDQLCGAGGLCRCRPGYTGTACQECSPGFH-------GFPS-CVPCHCSAEGSLHAA 688
+ G G C G C+ C+ GF +P C PCHC GSL+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 689 C--DPRS-------GQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPE 739
C D + G C C+ G+ CD C G +P C+A +C G DP
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFG- 484
Query: 740 AQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
PC+C+ +VEG C RCK GF+ L N +GC C C
Sbjct: 485 ---PCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 113 bits (283), Expect = 3e-24
Identities = 68/188 (36%), Positives = 85/188 (45%), Gaps = 39/188 (20%)
Query: 512 VGRCLCKPNFQGTHCELCAPGFY-----------GP---GCQPCQCSSPGVADDRCDPDT 557
+ +C C + G CE C PGFY GP C PCQC+ CDP+T
Sbjct: 1377 IEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG---HSSLCDPET 1433
Query: 558 GQCR-CRVGFEGATCDRCAPGYFHFPL-----CQLCGC---------SPAGTLPEGCDEA 602
C+ C+ G C+RCA GY+ CQ C C SP+ + EG D+
Sbjct: 1434 SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPS-CVAEGLDDY 1492
Query: 603 GRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTCDPRGALDQLCG-AGGLCRCRPGY 656
C + G +C+RC PGY G P +CQ C CDP G+L C G C CRPG
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 657 TGTACQEC 664
TG C C
Sbjct: 1553 TGRKCDGC 1560
Score = 110 bits (276), Expect = 2e-23
Identities = 66/185 (35%), Positives = 85/185 (45%), Gaps = 36/185 (19%)
Query: 559 QCRCRVGFEGATCDRCAPGYFHFP-------------LCQLCGCSPAGTLPEGCD-EAGR 604
+C C +G+ G +C+ C PG++ C C C+ +L CD E
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 605 CL-CQPEFAGPHCDRCRPGYHGF----PN-CQACTCDPRGALDQL---CGAGGL-----C 650
C CQ AG C+RC GY+G PN CQ C C + + C A GL
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 651 RCRPGYTGTACQECSPGFHGFP-----SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGL 705
C GY G C+ C+PG+ G P SC C C GSL CDP +G C+CRP TG
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 706 RCDTC 710
+CD C
Sbjct: 1556 KCDGC 1560
Score = 108 bits (270), Expect = 1e-22
Identities = 73/247 (29%), Positives = 98/247 (39%), Gaps = 52/247 (21%)
Query: 1915 CPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLG-----SSCQPC 1969
CPL +N +++C C+ G SC++C PGF P G + C+ C
Sbjct: 296 CPLDPATN-----------KSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC 344
Query: 1970 DCSGNG-----DPNLLFSDCDPLT-------GACRGCLRHTTGPRCEICAPGFYG----N 2013
+C G D N+ + G C C ++T G CE C GF+ +
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404
Query: 2014 ALLPGNCTRCDCTPCGT--EAC---DPHS------GHCLCKAGVTGRRCDRCQEGHFGFD 2062
P C C C P G+ E C + H+ G C CK G G CDRC G+ G+
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 2063 GCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRCQC 2119
C C G E P G C C+ G C C G++ L E +GC C C
Sbjct: 465 DCKACNCSGLGSKNE----DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Query: 2120 PG--GRC 2124
G RC
Sbjct: 521 SGVSNRC 527
Score = 108 bits (269), Expect = 1e-22
Identities = 71/259 (27%), Positives = 101/259 (38%), Gaps = 62/259 (23%)
Query: 321 QCTCQHNTCGGTCDRCCPG-FNQQPWKPATANSANECQSCNCYGHAT---------DCYY 370
QC C+ N G CD+C G F Q SA C CNC + C+
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQ--------SARGCVPCNCNSFGSKSFDCEESGQCWC 987
Query: 371 DPEVDRRRASQSLDGTY---QGGGVCIDCQH----------------HTTGVNCERCLPG 411
P V ++ + G + +GG +C H +T G C +C P
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPN 1047
Query: 412 FYRSPNHPLDSPHVCRRCNCES-DFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPS 470
+ H + + C+ CNC + D C TG+C C P FSG +C C+ G +P
Sbjct: 1048 TW---GHSITTG--CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR 1102
Query: 471 CYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCA 530
C + + LP CD ++ C + G+C CK N +G HC+ C
Sbjct: 1103 C--------NLCDCFLPGTDATTCD-----SETKKCSCSDQTGQCTCKVNVEGIHCDRCR 1149
Query: 531 PGFYG------PGCQPCQC 543
PG +G GC C C
Sbjct: 1150 PGKFGLDAKNPLGCSSCYC 1168
Score = 107 bits (266), Expect = 3e-22
Identities = 70/233 (30%), Positives = 90/233 (38%), Gaps = 62/233 (26%)
Query: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQ-IVNCDCSAAGTQGN 504
RC C N G+ CD C GF ++ AG + +C A G
Sbjct: 306 RCECEHNTCGDSCDQCCPGF----------------HQKPWRAGTFLTKTECEACNCHGK 349
Query: 505 A--CRKDPRVGR----------------CL-CKPNFQGTHCELCAPGFYGPG-------- 537
A C D V R C+ C N G +CE C GF+ P
Sbjct: 350 AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPR 409
Query: 538 -CQPCQCSSPGVADDRCDPDT---------GQCRCRVGFEGATCDRCAPGYFHFPLCQLC 587
CQPC C G ++ C D G C C+ GF G +CDRCA GY +P C+ C
Sbjct: 410 PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKAC 469
Query: 588 GCSPAGTLPEG-CDEAGRCLCQPEFAGPHCDRCRPGY-----HGFPNCQACTC 634
CS G+ E C G C+C+ G C RC+ G+ + C C C
Sbjct: 470 NCSGLGSKNEDPC--FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 100 bits (250), Expect = 2e-20
Identities = 62/189 (32%), Positives = 79/189 (41%), Gaps = 33/189 (17%)
Query: 650 CRCRPGYTGTACQECSPGFHGFPS-------------CVPCHCSAEGSLHAACDPRSGQC 696
C C GY+G +C+ C PGF+ S CVPC C+ SL CDP + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSIC 1436
Query: 697 -SCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCM---------- 745
+C+ G C+ C G Y C P+ + C+
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCA-CPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 746 -CRAHVEGPSCDRCKPGFWGLSPSNPEG-CTRCSCDLRGTLGGVAECQPGTGQCFCKPHV 803
C EG C+RC PG+ G SP NP G C C CD G+L C P TG C C+P
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLP--VPCDPVTGFCTCRPGA 1552
Query: 804 CGQACASCK 812
G+ C CK
Sbjct: 1553 TGRKCDGCK 1561
Score = 99.8 bits (247), Expect = 5e-20
Identities = 69/217 (31%), Positives = 94/217 (43%), Gaps = 31/217 (14%)
Query: 395 DCQHHTTGVNCERCLPGFYRSPNHP---LDSPHVCRRCNCESDFTDGTCEDLTGRCY-CR 450
DC +G++CE CLPGFYR + P P + C+ + C+ T C C+
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ 1440
Query: 451 PNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP---AGQIVNCDCSAAGTQGNACR 507
+ +G+ C+ CA G+ G P ND ++ P + + C A G C
Sbjct: 1441 HHTAGDFCERCALGYYGIVKGLP-----NDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 508 KDPRVGRCLCKPNFQGTHCELCAPGFYG----PG--CQPCQCSSPGVADDRCDPDTGQCR 561
PR ++G +CE CAPG+ G PG CQ C+C G CDP TG C
Sbjct: 1496 ACPR--------GYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCT 1547
Query: 562 CRVGFEGATCDRCAPGYFHFP---LCQLCGCSPAGTL 595
CR G G CD C ++H C CG G L
Sbjct: 1548 CRPGATGRKCDGCK--HWHAREGWECVFCGDECTGLL 1582
Score = 98.6 bits (244), Expect = 1e-19
Identities = 68/231 (29%), Positives = 87/231 (37%), Gaps = 59/231 (25%)
Query: 505 ACRKDPRVG--RCLCKPNFQGTHCELCAPGFYGPG-----------CQPCQCSSPGVADD 551
AC DP RC C+ N G C+ C PGF+ C+ C C +
Sbjct: 295 ACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKA---E 351
Query: 552 RCDPDTGQCR-------------------CRVGFEGATCDRCAPGYF-------HFPL-C 584
C D R C G C+ C G+F ++P C
Sbjct: 352 ECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPC 411
Query: 585 QLCGCSPAGTLPEGC--DEA--------GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTC 634
Q C C P G+L E C DE G C C+ F G CDRC GY G+P+C+AC C
Sbjct: 412 QPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC 471
Query: 635 DPRGALDQLCGAGGLCRCRPGYTGTACQECSPGF-----HGFPSCVPCHCS 680
G+ ++ G C C+ G C C GF + C C CS
Sbjct: 472 SGLGSKNE-DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 97.4 bits (241), Expect = 2e-19
Identities = 68/200 (34%), Positives = 84/200 (42%), Gaps = 34/200 (17%)
Query: 442 DLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGT 501
DL +C C +SG C+ C GF S P + T G V C C+
Sbjct: 1375 DLIEKCDCPLGYSGLSCEACLPGFYRLRS-QPGGRTPGPT------LGTCVPCQCN---- 1423
Query: 502 QGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG------PGCQPCQCS--------SP 546
G++ DP C C+ + G CE CA G+YG CQ C C SP
Sbjct: 1424 -GHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSP 1482
Query: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAGTLPEGCDE 601
+ D D C G+EG C+RCAPGY P CQ C C P G+LP CD
Sbjct: 1483 SCVAEGLD-DYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDP 1541
Query: 602 -AGRCLCQPEFAGPHCDRCR 620
G C C+P G CD C+
Sbjct: 1542 VTGFCTCRPGATGRKCDGCK 1561
Score = 95.5 bits (236), Expect = 9e-19
Identities = 65/220 (29%), Positives = 88/220 (40%), Gaps = 49/220 (22%)
Query: 321 QCTCQHNTCGGTCDRCCPGF---NQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRR 377
+C C G +C+ C PGF QP + C C C GH++ C DPE
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC--DPETS-- 1434
Query: 378 RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC-----E 432
+C +CQHHT G CERC G+Y P+ C++C C
Sbjct: 1435 --------------ICQNCQHHTAGDFCERCALGYYGIVK---GLPNDCQQCACPLISSS 1477
Query: 433 SDFTDG-TCEDLTG-RC-YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAG 489
++F+ E L RC C + G+ C+ CA G+TG P P G
Sbjct: 1478 NNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG---------------NPGG 1522
Query: 490 QIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
C+C G+ C DP G C C+P G C+ C
Sbjct: 1523 SCQECECDPYGSLPVPC--DPVTGFCTCRPGATGRKCDGC 1560
Score = 92.0 bits (227), Expect = 1e-17
Identities = 54/179 (30%), Positives = 72/179 (40%), Gaps = 14/179 (7%)
Query: 695 QCSCRPRVTGLRCDTCVPGAYNF--------PYCEAGSCHPAGLAPVDPAL-PEAQVPCM 745
+C C +GL C+ C+PG Y P G+C P PE +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 746 CRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGG-----VAECQPGTGQCFCK 800
C+ H G C+RC G++G+ P C +C+C L + VAE C
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 801 PHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
GQ C C G+ G C+ C CD G+L C+P TG C CRP G C
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Score = 90.1 bits (222), Expect = 4e-17
Identities = 70/247 (28%), Positives = 92/247 (37%), Gaps = 57/247 (23%)
Query: 626 FPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFP----------SCV 675
+ + +AC DP + C C G +C +C PGFH P C
Sbjct: 290 YGHARACPLDPATNKSR-------CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECE 342
Query: 676 PCHC--SAEGSLHAACDPR-------------SGQC-SCRPRVTGLRCDTCVPGAY---- 715
C+C AE + R G C +C G+ C+TC G +
Sbjct: 343 ACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKG 402
Query: 716 ---NFPY-CEAGSCHPAGLAPVDPALPE-------AQVPCMCRAHVEGPSCDRCKPGFWG 764
N+P C+ C P G E A C C+ G SCDRC G+ G
Sbjct: 403 VSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG 462
Query: 765 LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYF 824
C C+C LG E P G C CK +V G C+ CK GFF L + ++
Sbjct: 463 YPD-----CKACNCS---GLGSKNE-DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWK 513
Query: 825 GCRSCRC 831
GC C C
Sbjct: 514 GCDECFC 520
Score = 85.5 bits (210), Expect = 9e-16
Identities = 51/163 (31%), Positives = 73/163 (44%), Gaps = 23/163 (14%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
C C+GH+ CD + + CQH+T G C+RC G+ N+CQ C
Sbjct: 1420 CQCNGHSSLCDPET-----SICQNCQHHTAGDFCERCALGY-----YGIVKGLPNDCQQC 1469
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
C ++ + P ++ LD Y+ C C G CERC PG+ SP +P
Sbjct: 1470 ACPLISSSNNFSPSC----VAEGLD-DYR----CTACPRGYEGQYCERCAPGYTGSPGNP 1520
Query: 420 LDSPHVCRRCNCES-DFTDGTCEDLTGRCYCRPNFSGERCDVC 461
S C+ C C+ C+ +TG C CRP +G +CD C
Sbjct: 1521 GGS---CQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 78.6 bits (192), Expect = 1e-13
Identities = 57/200 (28%), Positives = 80/200 (40%), Gaps = 41/200 (20%)
Query: 695 QCSCRPRVTGLRCDTCVPGAYNFPY----------CEAGSCH-PAGLAPVDPALPEAQVP 743
+C C G CD C PG + P+ CEA +CH A D + +
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 744 ------------CM-CRAHVEGPSCDRCKPGFW---GLSPSNPEGCTRCSCDLRGTLGGV 787
C+ C + G +C+ C GF+ G+SP+ P C C CD G+L V
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 788 -------AECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS 840
A G C CK G +C C G+ G Y C++C C G+ +
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG-----YPDCKACNCSGLGSKNE- 479
Query: 841 CEPRTGVCRCRPNTQGPTCS 860
+P G C C+ N +G CS
Sbjct: 480 -DPCFGPCICKENVEGGDCS 498
Score = 71.2 bits (173), Expect = 2e-11
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 14/116 (12%)
Query: 1431 YNNGARPCGCHEVGATGPTCEP---------FGGQCPCHAHVIGRDCSRCATGYWGFPNC 1481
Y +PC C +G+ C G C C G C RCA GY G+P+C
Sbjct: 407 YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDC 466
Query: 1482 RPCDC---GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHP--LVGCEECNCSG 1532
+ C+C G++ D G CIC DC C+ F GC+EC CSG
Sbjct: 467 KACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Score = 62.4 bits (150), Expect = 8e-09
Identities = 49/189 (25%), Positives = 62/189 (32%), Gaps = 47/189 (24%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
C C + CD K +C C NT G C +C P W + C++C
Sbjct: 1014 CECSHLGNNCDPKTG------RCICPPNTIGEKCSKCAP----NTWGHSITTG---CKAC 1060
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
NC SLD +C +G C C G + P
Sbjct: 1061 NC----------------STVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-- 1102
Query: 420 LDSPHVCRRCNCESDFTDGT----------CEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
C C+C TD T C D TG+C C+ N G CD C G G
Sbjct: 1103 ------CNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLD 1156
Query: 470 SCYPTPSSS 478
+ P SS
Sbjct: 1157 AKNPLGCSS 1165
Score = 50.4 bits (119), Expect = 3e-05
Identities = 36/138 (26%), Positives = 45/138 (32%), Gaps = 43/138 (31%)
Query: 1528 CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP----------RCRPC 1577
C C G DP T+ +C+C N G CD C PGFH P C C
Sbjct: 287 CICYGHARACPLDPA--TNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC 344
Query: 1578 DCHEAG----------------------TAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1615
+CH GVC C +N G C+ C+ G F
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVC------INCTQNTAGINCETCTDGFF 398
Query: 1616 ---SLDAANPKGCTRCFC 1630
+ P+ C C C
Sbjct: 399 RPKGVSPNYPRPCQPCHC 416
Score = 43.9 bits (102), Expect = 0.003
Identities = 36/125 (28%), Positives = 47/125 (37%), Gaps = 19/125 (15%)
Query: 1399 DFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCP 1458
DF CA GY+ C+ A L NN + C + T P G +
Sbjct: 1446 DFCERCAL-GYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE-- 1502
Query: 1459 CHAHVIGRDCSRCATGYWGFP-----NCRPCDCGAR-----LCDELTGQCICPPRTIPPD 1508
G+ C RCA GY G P +C+ C+C CD +TG C C P
Sbjct: 1503 ------GQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 1509 CLLCQ 1513
C C+
Sbjct: 1557 CDGCK 1561
Score = 43.5 bits (101), Expect = 0.004
Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%)
Query: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPG-FNQQPWKPATANSANECQSCN 360
C C D T QCTC+ N G CDRC PG F P C SC
Sbjct: 1118 CDSETKKCSCSDQTG----QCTCKVNVEGIHCDRCRPGKFGLDAKNPL------GCSSCY 1167
Query: 361 CYGHATDC 368
C+G T C
Sbjct: 1168 CFGTTTQC 1175
Score = 39.7 bits (91), Expect = 0.056
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 1436 RPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELT 1495
+ C C +G+ +P G C C +V G DCSRC +G++ C C ++
Sbjct: 467 KACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVS 524
Query: 1496 GQC 1498
+C
Sbjct: 525 NRC 527
Score = 38.9 bits (89), Expect = 0.096
Identities = 35/135 (25%), Positives = 45/135 (33%), Gaps = 38/135 (28%)
Query: 2065 GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGY----WG----LPEQGCRR 2116
G R C PA S +C C T G C +C PG+ W L + C
Sbjct: 291 GHARACPLDPATNKS-------RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 2117 CQCPG--GRC--DPHTGR-----------------CNCPPGLSGERCDTCSQQHQVPVPG 2155
C C G C D + R NC +G C+TC+ P
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGV 403
Query: 2156 GPVGHSIHCEVCDHC 2170
P + C+ C HC
Sbjct: 404 SP-NYPRPCQPC-HC 416
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 469 bits (1207), Expect = e-131
Identities = 275/781 (35%), Positives = 377/781 (48%), Gaps = 77/781 (9%)
Query: 1456 QCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGARL----CDELT------ 1495
+C C + G C +C G+ P C C+C + DE
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 1496 ----------GQCI-CPPRTIPPDCLLCQPQTF---GCHPLVG--CEECNCSGPGIQELT 1539
G CI C T +C C F G P C+ C+C G
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGS---L 422
Query: 1540 DPTCDTDS---------GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCD 1590
+ C D G C C+ G CD C+ G+ GYP C+ C+C G+ D
Sbjct: 423 NEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNE--D 480
Query: 1591 PLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDM 1650
P G C CKENV+G C +C G F+L N KGC CFC G + RC+SS +T + DM
Sbjct: 481 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM 540
Query: 1651 EGWVLLSTDRQVVPHERQP---GTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSS 1707
GW L ++ +Q + + +A+P ++ YW AP YLG+++ +
Sbjct: 541 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSY---YWSAPAPYLGNKLPA 597
Query: 1708 YGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMSI-TFLEPAYPTPGHVHRGQLQLVE 1766
GG L + + + + + + ++L+GN +SI T + Y P H L L E
Sbjct: 598 VGGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKE 657
Query: 1767 GNFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVF-LRRVALEVA-SPAGQGAL 1824
+F T V R+E M VLA+L+++ ++ +S A+F L V LE A S G++
Sbjct: 658 ESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSI 717
Query: 1825 ASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQ 1884
A+ VE+C CP Y G SC+ C P R +F G C PCQC GH++ C +G C++C+
Sbjct: 718 AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCK 777
Query: 1885 HNTEGAHCERCQAGFVSS-RDDPSAPCVSCPCPLSVPSNNFAEGCVLRG--GRTQCLCKP 1941
+T G +C++C GF S C C CPL++PSNNF+ C L G C
Sbjct: 778 DHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPV 837
Query: 1942 GYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGP 2001
GY G CERCA G+FG P V G SCQPC C+ N D ++ S CD L+G+C C TTG
Sbjct: 838 GYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS-CDSLSGSCLICKPGTTGR 896
Query: 2002 RCEICAPGFYGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRCQEGHF 2059
CE+CA G++G+A+ NC C C G+ E C +G C C+A V G+RCD+C+ G F
Sbjct: 897 YCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTF 956
Query: 2060 GFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC 2119
G GC PC C S +SGQC C+PG G +C CA GY+ E GC C+C
Sbjct: 957 GLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACEC 1016
Query: 2120 P--GGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSI--HCEVCDHCVVLLL 2175
G CDP TGRC CPP GE+C C+ GHSI C+ C+ V L
Sbjct: 1017 SHLGNNCDPKTGRCICPPNTIGEKCSKCAP--------NTWGHSITTGCKACNCSTVGSL 1068
Query: 2176 D 2176
D
Sbjct: 1069 D 1069
Score = 440 bits (1131), Expect = e-122
Identities = 241/574 (41%), Positives = 314/574 (54%), Gaps = 84/574 (14%)
Query: 15 GPRGPAPLLLVGLALLGAARAR------EEAGGGFSLHPPYFNLAEGARIAASATCGEEA 68
G G LLL+ L G R +A L P NLA A I +ATCGE+
Sbjct: 3 GAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKG 62
Query: 69 PARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICT--AANSNKAHPASNAIDGTER 126
P ++YCKLV P Q +R C IC ++N N+ HP +NAIDG
Sbjct: 63 P---------EMYCKLVEHV-----PGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNT 108
Query: 127 WWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQ 186
WWQSP + G+EY+ V +TLDL QVF +AYV++K ANSPRP W+LERS+D Y+PWQ
Sbjct: 109 WWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQ 167
Query: 187 FFASSKRDCLE------RFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG 240
+ A + +CL R GP + +DD ICT+ YS+I PLENGEI +SL+NGRP
Sbjct: 168 YHAVTDTECLTLYNIYPRTGPPSY---AKDDEVICTSFYSKIHPLENGEIHISLINGRPS 224
Query: 241 AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT-----VTRRYYYSIKDIS 295
A + SP L EFT A +RLRF R TL LM A +DP VTRRYYYS+KDIS
Sbjct: 225 ADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDIS 282
Query: 296 IGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANE 355
+GG C+C+GHA AC T+ R C C+HNTCG +CD+CCPGF+Q+PW+ T + E
Sbjct: 283 VGGMCICYGHARACPLDPATNKSR--CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTE 340
Query: 356 CQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRS 415
C++CNC+G A +CYYD V RR S ++ G Y GGGVCI+C +T G+NCE C GF+R
Sbjct: 341 CEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400
Query: 416 PNHPLDSPHVCRRCNCE--SDFTDGTCED--------LTGRCYCRPNFSGERCDVCAEGF 465
+ P C+ C+C+ + +D G C+C+ F G CD CA G+
Sbjct: 401 KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Query: 466 TGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTH 525
TG+P C C+CS G++ +DP G C+CK N +G
Sbjct: 461 TGYPDCKA--------------------CNCSGLGSK----NEDPCFGPCICKENVEGGD 496
Query: 526 CELCAPGFYG------PGCQPCQCSSPGVADDRC 553
C C GF+ GC C CS +RC
Sbjct: 497 CSRCKSGFFNLQEDNWKGCDECFCSG---VSNRC 527
Score = 394 bits (1011), Expect = e-108
Identities = 225/634 (35%), Positives = 303/634 (47%), Gaps = 77/634 (12%)
Query: 1424 AASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN--C 1481
A + L G PC C+ G+ CE GQC C V G+ C RCA GY+ F C
Sbjct: 953 AGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGC 1011
Query: 1482 RPCDCG--ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELT 1539
C+C CD TG+CICPP TI C C P T+G GC+ CNCS G
Sbjct: 1012 TACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGS---L 1068
Query: 1540 DPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDP-------- 1591
D C+ ++GQC C P +G +C CS G YPRC CDC GT CD
Sbjct: 1069 DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCS 1128
Query: 1592 -LTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDM 1650
TGQC CK NV+G CD+C G F LDA NP GC+ C+CFG T +C + +
Sbjct: 1129 DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGL------I 1182
Query: 1651 EGWVLLSTDRQVVP-------HERQPGT-----------EMLRADLRHVPEAVPEAFPEL 1692
WV L ++ ++P H G +++R DL P
Sbjct: 1183 RTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEP---------F 1233
Query: 1693 YWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMS---ITFLEP 1749
YW+ P + G ++ +YGG L+Y ++ E + F P V+++G + I
Sbjct: 1234 YWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYN--PQVIIRGGTPTHARIIVRHM 1291
Query: 1750 AYPTPGHVHRGQLQLVEGNFRH----TETRNTVSREELMMVLASLEQLQIRALFSQISSA 1805
A P G + R ++++ E +++ TV+RE+ + +L + + I+A +
Sbjct: 1292 AAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQ 1351
Query: 1806 VFLRRVALEVASPAGQGAL----ASNVELCLCPASYRGDSCQECAPGFYR-------DVK 1854
+ +++EVA G+G A +E C CP Y G SC+ C PGFYR
Sbjct: 1352 SRISEISMEVAEQ-GRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTP 1410
Query: 1855 GLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCP 1914
G LG CVPCQC+GHS C P + +C +CQH+T G CERC G+ C C
Sbjct: 1411 GPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCA 1470
Query: 1915 CPLSVPSNNFAEGCVLRG-GRTQC-LCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCS 1972
CPL SNNF+ CV G +C C GY G CERCAPG+ G+P G SCQ C+C
Sbjct: 1471 CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD 1530
Query: 1973 GNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEIC 2006
G L CDP+TG C C TG +C+ C
Sbjct: 1531 PYGS---LPVPCDPVTGFCT-CRPGATGRKCDGC 1560
Score = 344 bits (882), Expect = 1e-93
Identities = 437/1897 (23%), Positives = 738/1897 (38%), Gaps = 292/1897 (15%)
Query: 1936 QCLCKPGYAGASCERCAPGFFG--------NPLVLGSSCQPCDCSGNGDPNLLFSDCDPL 1987
+C C GY+G SCE C PGF+ P +C PC C+G+ S CDP
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHS------SLCDPE 1432
Query: 1988 TGACRGCLRHTTGPRCEICAPGFYGNAL-LPGNCTRCDC----------TPCGTEACDPH 2036
T C+ C HT G CE CA G+YG LP +C +C C C E D +
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 2037 SGHC-LCKAGVTGRRCDRCQEGHFGFDG--CGGCRPCACGP-AAEGSECHPQSGQCHCRP 2092
C C G G+ C+RC G+ G G G C+ C C P + C P +G C CRP
Sbjct: 1493 --RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRP 1550
Query: 2093 GTMGPQCRECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVP 2152
G G +C C +W E G C C
Sbjct: 1551 GATGRKCDGCK--HWHARE---------------------------GWECVFCG------ 1575
Query: 2153 VPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASI 2212
D C LLL DL R + + + IN + A +++ +
Sbjct: 1576 ---------------DECTGLLLGDLAR-------LEQMVMSINLTGPLPAP-YKMLYGL 1612
Query: 2213 ADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATL 2272
++ +L+ L P+ + +++ E +L + L +A Q E T
Sbjct: 1613 ENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTN 1672
Query: 2273 GHAKTLLAAIRAVDRTLSELMSQTGHLG--LANASAPSGEQLLRTLAEVERLLWEMRARD 2330
AK+L I+ + R + + L L L E+++++ E+R ++
Sbjct: 1673 TRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKN 1732
Query: 2331 LGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNR 2390
L + AE EL AA+ LL +V++ EN+ + R++LA ++ + D + L
Sbjct: 1733 LETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLRE 1792
Query: 2391 AVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQA 2450
A D REA L + NQ+ + ++K+ + ++ TL D L RL ++
Sbjct: 1793 ATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSI 1852
Query: 2451 KEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVE---AAEAHAQQLGQLALNLSSIIL 2507
+ +E + L L ++ S +L E AE+HA QL + L I+
Sbjct: 1853 IDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILD 1912
Query: 2508 DVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHT--WATVVR-------QGL 2558
+ ++ A A AYS I + AE A +A A AT R +G
Sbjct: 1913 EAK--NISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGC 1970
Query: 2559 VDRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAML 2618
+ ++ ++L + L + + + L G +T++ + A+ L + L
Sbjct: 1971 LQKSFRILNEAKKLANDVKENEDH-------LNGLKTRIENADARNGDLLRTLNDTLGKL 2023
Query: 2619 AMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGL----------- 2667
+ ++T+ K+ K A +A DTA V +Q+ + +N++ + Y L
Sbjct: 2024 SAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVV 2083
Query: 2668 RGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASIGRVRELIAQAR 2727
+ + + DA +V LE+ +L+ KL + + L +I ++ELI QAR
Sbjct: 2084 KDPSKNKIIADADATVKNLEQEADRLIDKL-----KPIKELEDNLKKNISEIKELINQAR 2138
Query: 2728 GAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPGQGTEDRFVMYMGS 2787
A+ +KV + G +RT + +Y + ++ D + Y+GS
Sbjct: 2139 KQANSIKVSVSSGGDC---IRTYKPEIKKGSYNNIVVNVK-------TAVADNLLFYLGS 2188
Query: 2788 RQATGDYMGVSLRDKKVHWVYQLGEAGPAV----LSIDEDIGEQFAAVSLDRTLQFGHMS 2843
+ D++ + +R KV +++ +G V L+ID+ + A RT + G +S
Sbjct: 2189 AKFI-DFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVA---SRTGRNGTIS 2244
Query: 2844 VTV----ERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGC 2899
V + ++ T T PG +L++ + +F VGG +R + GC
Sbjct: 2245 VRALDGPKASIVPSTHHSTSPPGYT-ILDVDANAMLF-VGGLTGKLKKADAVRVITFTGC 2302
Query: 2900 IEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGS-YLDGTGFARIS--- 2955
+ + + + L+NF R + D + C S D ++G+ DG G+A +S
Sbjct: 2303 MGETYFDNKPIGLWNF-REKEGDC---KGCTVSPQVED---SEGTIQFDGEGYALVSRPI 2355
Query: 2956 -FDSQISTTKRFEQELRLVSYSGVLFFL--KQQSQFLCLAVQEGSLVLLYDFGAGLKKAV 3012
+ IST + R S S +L +L + F+ + + +G + + YD G+G+ V
Sbjct: 2356 RWYPNISTVM---FKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVV 2412
Query: 3013 PLQPPPPLTSASKAIQVFLLGGSRKRVLVRV-------ERATVYSVEQDN---DLELADA 3062
Q + F L +K+ + + E S +N DL+ D
Sbjct: 2413 SNQ-----NHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDK 2467
Query: 3063 YYLGGVPPDQLPPSLRRLFPTGGSVRGCVKGIK-ALGKYVDLKRLNTTGVSAGCTADLLV 3121
Y GG+P + R GC+K I+ + Y L + GV+ GC+ + +
Sbjct: 2468 IYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVY 2527
Query: 3122 GRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYY-------------RASP 3168
++F GF+ L + P+ F + +S ++ R +
Sbjct: 2528 --TVSFPKPGFVEL---SPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTG 2582
Query: 3169 DGLCQVSLQQGRVSLQLLRTEVKTQAG---------FADGAPHYVAFYSNATGVWLYVDD 3219
+ L +GR+ + L T +T F DG H V + VD+
Sbjct: 2583 QAYYVILLNRGRLEVH-LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDE 2641
Query: 3220 QLQQMKPHR-------------GPPPELQPQPEGPPRLLLGGLPESGTIYNFSGCISNVF 3266
+ M+ G PPE QP P L +P F GCI N+
Sbjct: 2642 NRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSP-------LRNIPP------FEGCIWNLV 2688
Query: 3267 VQRLLGPQRVFDLQQNLGSVNVSTG-CA-PALQAQTPGLGPRGL----QATARKASRRSR 3320
+ + D + + N G CA L+ G P + + A
Sbjct: 2689 INSV-----PMDFARPVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPT 2743
Query: 3321 QPARHPACMLPPHLRTTRDSYQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLL 3380
H C S QFG S +SH+ + +N ++ + V + GLL
Sbjct: 2744 PVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLF 2803
Query: 3381 FTAR----------LRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSV 3430
+ AR LR G P + L +G + G+WHK+ +
Sbjct: 2804 YMARINHADFATVQLRNGLPYFSYDLGSGD-----------THTMIPTKINDGQWHKIKI 2852
Query: 3431 RWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSKL-PVTVGFSG 3489
K +L DGA + L+VGGLP + + ++ PVT G
Sbjct: 2853 MRSKQEGILYVDGA----SNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDG 2908
Query: 3490 CVKRLRLHGRP--LGAPTRMAGVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLEL 3547
CV+ L + P L PT V C + G +F G+G + L D+ +E
Sbjct: 2909 CVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDGTGFAKAVGGFKVGL-DLLVEF 2966
Query: 3548 EVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFST--SVTRPSVLCDGQW 3605
E R TG++ + + + +++ +++++ D+GAG F+ P LCDGQW
Sbjct: 2967 EFRTTTTTGVLLGISSQKMDG-MGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQW 3025
Query: 3606 HRLAVMKSGNVLRLEVDAQSNHTVGPLLAA-AAGAPAPLYLGGLPEPMAVQPWPPA--YC 3662
H++ K + + L VD P A+ +A P+++GG P+ + + +
Sbjct: 3026 HKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFR 3085
Query: 3663 GCMRRLAVNRS-----PVAMTRSVEVHGAVGASGCPA 3694
GC+R L + + V +++E+ G S CPA
Sbjct: 3086 GCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS-CPA 3121
Score = 276 bits (707), Expect = 2e-73
Identities = 160/509 (31%), Positives = 216/509 (42%), Gaps = 87/509 (17%)
Query: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
C C G +C+ C P + C+ C C+GHA C
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD------------ 767
Query: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCE 441
D T G C++C+ HT G C++CLPGFY P C+ C C +
Sbjct: 768 --DVT----GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSN--- 816
Query: 442 DLTGRCY-----------CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQ 490
+ + C+ C ++G RC+ CAEG+ G PS +P G
Sbjct: 817 NFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS---------------VPGGS 861
Query: 491 IVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG-----CQPCQCS 544
C C+ D G CL CKP G +CELCA G++G CQPC+C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCN 921
Query: 545 SPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDE 601
+ G + C TGQC CR +G CD+C G F C C C+ G+ C+E
Sbjct: 922 AGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE 981
Query: 602 AGRCLCQPEFAGPHCDRCRPGYHGFPN--CQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
+G+C CQP G CDRC GY F C AC C G + G C C P G
Sbjct: 982 SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG--NNCDPKTGRCICPPNTIGE 1039
Query: 660 ACQECSPGFHGFP---SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYN 716
C +C+P G C C+CS GSL C+ +GQC+C P+ +G +C C G +N
Sbjct: 1040 KCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWN 1099
Query: 717 FPYCEAGSCHPAGLAPVDPALPEAQV----------PCMCRAHVEGPSCDRCKPGFWGLS 766
+P C C G D +++ C C+ +VEG CDRC+PG +GL
Sbjct: 1100 YPRCNLCDCFLPG---TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLD 1156
Query: 767 PSNPEGCTRCSCDLRGTLGGVAECQPGTG 795
NP GC+ C C G +C G
Sbjct: 1157 AKNPLGCSSCYC-----FGTTTQCSEAKG 1180
Score = 261 bits (666), Expect = 1e-68
Identities = 150/439 (34%), Positives = 208/439 (47%), Gaps = 65/439 (14%)
Query: 300 CVCHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C C GHA++CD D T +C C+ +T G CD+C PGF +P T ++ +CQ
Sbjct: 757 CQCFGHAESCD--DVTG----ECLNCKDHTGGPYCDKCLPGFYGEP----TKGTSEDCQP 806
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C + + P R+ G +C C TG CERC G++ P+
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSL---------GLICDGCPVGYTGPRCERCAEGYFGQPSV 857
Query: 419 PLDSPHVCRRCNCESDFT-DGTCEDLTGRC-YCRPNFSGERCDVCAEGFTGFPSCYPTPS 476
P S C +CN DF+ G+C+ L+G C C+P +G C++CA+G+ G
Sbjct: 858 PGGSCQPC-QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFG--------- 907
Query: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG- 535
+ A C C+A G+ C + G+C C+ N QG C+ C G +G
Sbjct: 908 -------DAVDAKNCQPCRCNAGGSFSEVCHS--QTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 536 ---PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL--CQLCGCS 590
GC PC C+S G C+ ++GQC C+ G G CDRCA GYF+F C C CS
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECS 1017
Query: 591 PAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRP---GYHGFPNCQACTCDPRGALDQLCGA 646
G CD + GRC+C P G C +C P G+ C+AC C G+LD C
Sbjct: 1018 HLG---NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNV 1074
Query: 647 G-GLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACD---------PRSGQC 696
G C C P ++G C ECS G +P C C C G+ CD ++GQC
Sbjct: 1075 NTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQC 1134
Query: 697 SCRPRVTGLRCDTCVPGAY 715
+C+ V G+ CD C PG +
Sbjct: 1135 TCKVNVEGIHCDRCRPGKF 1153
Score = 239 bits (610), Expect = 4e-62
Identities = 158/491 (32%), Positives = 204/491 (41%), Gaps = 71/491 (14%)
Query: 380 SQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT 439
S DG+ C TG +CE C P +R N + +C C C +
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPR-HRRVNGTIFGG-ICEPCQCFGHAE--S 765
Query: 440 CEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSA 498
C+D+TG C C+ + G CD C GF G PT +S D + C C
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYG----EPTKGTSEDCQP----------CACPL 811
Query: 499 AGTQGN---ACRKDPRVGRCL--CKPNFQGTHCELCAPGFYG----PG--CQPCQC---- 543
N C D +G C + G CE CA G++G PG CQPCQC
Sbjct: 812 NIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNL 871
Query: 544 --SSPGVADDRCDPDTGQCR-CRVGFEGATCDRCAPGYFHFPL----CQLCGCSPAGTLP 596
S PG CD +G C C+ G G C+ CA GYF + CQ C C+ G+
Sbjct: 872 DFSIPG----SCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFS 927
Query: 597 EGC-DEAGRCLCQPEFAGPHCDRCRPGYHGFPN---CQACTCDPRGALDQLCGAGGLCRC 652
E C + G+C C+ G CD+C+ G G + C C C+ G+ C G C C
Sbjct: 928 EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWC 987
Query: 653 RPGYTGTACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC 710
+PG TG C C+ G+ F C C CS G+ CDP++G+C C P G +C C
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN---NCDPKTGRCICPPNTIGEKCSKC 1044
Query: 711 VPGAYNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSP 767
P + C+A +C G + Q C C G C C G W
Sbjct: 1045 APNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ--CNCHPKFSGAKCTECSRGHW---- 1098
Query: 768 SNPEGCTRCSCDLRGTLGGVAE-------CQPGTGQCFCKPHVCGQACASCKDGFFGLDQ 820
N C C C L GT + C TGQC CK +V G C C+ G FGLD
Sbjct: 1099 -NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA 1157
Query: 821 ADYFGCRSCRC 831
+ GC SC C
Sbjct: 1158 KNPLGCSSCYC 1168
Score = 234 bits (598), Expect = 9e-61
Identities = 157/464 (33%), Positives = 201/464 (43%), Gaps = 80/464 (17%)
Query: 436 TDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCD 495
TDG+ C C P ++G C+ SC+P N T + G C
Sbjct: 713 TDGSIAAAVEVCQCPPGYTGSSCE----------SCWPRHRRVNGT----IFGGICEPCQ 758
Query: 496 CSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGP-------GCQPCQCS--- 544
C G+A D G CL CK + G +C+ C PGFYG CQPC C
Sbjct: 759 CF-----GHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 545 -----SPGVADDR-----CDPDTGQCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGC 589
SP DR CD C VG+ G C+RCA GYF P CQ C C
Sbjct: 814 PSNNFSPTCHLDRSLGLICDG------CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQC 867
Query: 590 SPA--GTLPEGCDE-AGRCL-CQPEFAGPHCDRCRPGYHG----FPNCQACTCDPRGALD 641
+ ++P CD +G CL C+P G +C+ C GY G NCQ C C+ G+
Sbjct: 868 NDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFS 927
Query: 642 QLCGAG-GLCRCRPGYTGTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCS 697
++C + G C CR G C +C G G S CVPC+C++ GS C+ SGQC
Sbjct: 928 EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE-ESGQCW 986
Query: 698 CRPRVTGLRCDTCVPGAYNFPY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC 755
C+P VTG +CD C G +NF C A C G DP C+C + G C
Sbjct: 987 CQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG-NNCDPKTGR----CICPPNTIGEKC 1041
Query: 756 DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGF 815
+C P WG S + GC C+C G+L +C TGQC C P G C C G
Sbjct: 1042 SKCAPNTWGHSITT--GCKACNCSTVGSLD--FQCNVNTGQCNCHPKFSGAKCTECSRGH 1097
Query: 816 FGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
+ +Y C C C + G +C+ T C C T TC
Sbjct: 1098 W-----NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTC 1136
Score = 226 bits (577), Expect = 2e-58
Identities = 130/394 (32%), Positives = 173/394 (43%), Gaps = 60/394 (15%)
Query: 515 CLCKPNFQGTHCELCAPG-------FYGPGCQPCQCSSPGVADDRCDPDTGQC-RCRVGF 566
C C P + G+ CE C P +G C+PCQC + CD TG+C C+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHA---ESCDDVTGECLNCKDHT 780
Query: 567 EGATCDRCAPGYFHFPL------CQLCGCS---PAGTLPEGCDEAGRCL------CQPEF 611
G CD+C PG++ P CQ C C P+ C R L C +
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTC-HLDRSLGLICDGCPVGY 839
Query: 612 AGPHCDRCRPGYHGFPN-----CQACTCDPR------GALDQLCGAGGLCRCRPGYTGTA 660
GP C+RC GY G P+ CQ C C+ G+ D L +G C+PG TG
Sbjct: 840 TGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSL--SGSCLICKPGTTGRY 897
Query: 661 CQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYN 716
C+ C+ G+ G +C PC C+A GS C ++GQC CR V G RCD C G +
Sbjct: 898 CELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFG 957
Query: 717 FPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGC 773
C +C+ G D E C C+ V G CDRC G++ GC
Sbjct: 958 LQSARGCVPCNCNSFGSKSFDC---EESGQCWCQPGVTGKKCDRCAHGYFNFQEG---GC 1011
Query: 774 TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI 833
T C C G C P TG+C C P+ G+ C+ C +G + GC++C C
Sbjct: 1012 TACECSHLGN-----NCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKACNCST 1064
Query: 834 GGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
G+L C TG C C P G C+E +R H+
Sbjct: 1065 VGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHW 1098
Score = 167 bits (422), Expect = 2e-40
Identities = 119/414 (28%), Positives = 171/414 (41%), Gaps = 88/414 (21%)
Query: 1833 CPASYRGDSCQECAPGFYRD--VKGLFLGRCVPCQCHGHSDRCLPGS-----GVCVDCQH 1885
CP Y G C+ CA G++ V G G C PCQC+ + D +PGS G C+ C+
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPG---GSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP 891
Query: 1886 NTEGAHCERCQAGFVSSRDDPS--APCV----------------SCPCPLSVPSNNF--- 1924
T G +CE C G+ D PC C C +V
Sbjct: 892 GTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951
Query: 1925 ---------AEGCV-----LRGGRT-------QCLCKPGYAGASCERCAPGFFGNPLVLG 1963
A GCV G ++ QC C+PG G C+RCA G+F
Sbjct: 952 KAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFN---FQE 1008
Query: 1964 SSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRC 2023
C C+CS G+ +CDP TG C C +T G +C CAP +G+++ G C C
Sbjct: 1009 GGCTACECSHLGN------NCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITTG-CKAC 1060
Query: 2024 DCTPCGTE--ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCR-------PCACGP 2074
+C+ G+ C+ ++G C C +G +C C GH+ + C C C
Sbjct: 1061 NCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDS 1120
Query: 2075 AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRRCQCPGGRCDPHTGRC 2131
+ C Q+GQC C+ G C C PG +GL + GC C C G T +C
Sbjct: 1121 ETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFG-----TTTQC 1175
Query: 2132 NCPPGLSGERCDTCSQQHQVPVPGGPVGHSI-------HCEVCDHCVVLLLDDL 2178
+ GL ++Q +P+ + H+ H E+ H + L+ +DL
Sbjct: 1176 SEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAH-MDLMREDL 1228
Score = 136 bits (343), Expect = 3e-31
Identities = 80/242 (33%), Positives = 107/242 (44%), Gaps = 31/242 (12%)
Query: 643 LCGAGGLCRCRPGYTGTACQECSPG--------FHGFPSCVPCHCSAEGSLHAACDPRSG 694
+ A +C+C PGYTG++C+ C P F G C PC C +CD +G
Sbjct: 717 IAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGI--CEPCQCFGHAE---SCDDVTG 771
Query: 695 QC-SCRPRVTGLRCDTCVPGAYNFPYCEAGS-CHPAGLAPVDPALPEAQVPCM------- 745
+C +C+ G CD C+PG Y P C P P++ C
Sbjct: 772 ECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCA-CPLNIPSNNFSPTCHLDRSLGL 830
Query: 746 ----CRAHVEGPSCDRCKPGFWGLSPSNPEG-CTRCSCDLRGTLGGVAECQPGTGQCF-C 799
C GP C+RC G++G PS P G C C C+ C +G C C
Sbjct: 831 ICDGCPVGYTGPRCERCAEGYFG-QPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 800 KPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
KP G+ C C DG+FG D D C+ CRC+ GG+ + C +TG C CR N QG C
Sbjct: 890 KPGTTGRYCELCADGYFG-DAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 860 SE 861
+
Sbjct: 949 DK 950
Score = 117 bits (293), Expect = 2e-25
Identities = 85/269 (31%), Positives = 112/269 (41%), Gaps = 67/269 (24%)
Query: 1825 ASNVELCLCPASYRGDSCQECAPGFYRDV--KGLFLGR--CVPCQCHGHSDRC------- 1873
A+N C C + GDSC +C PGF++ G FL + C C CHG ++ C
Sbjct: 301 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA 360
Query: 1874 -----------LPGSGVCVDCQHNTEGAHCERCQAGFVSSR---DDPSAPCVSCPCPLSV 1919
G GVC++C NT G +CE C GF + + PC C C
Sbjct: 361 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCD--- 417
Query: 1920 PSNNFAEGCV-----LRGGRT--QCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCS 1972
P + E CV R G C CK G+ G SC+RCA G+ G P C+ C+CS
Sbjct: 418 PIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP-----DCKACNCS 472
Query: 1973 GNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA 2032
G G N DP G C C + G C C GF+ L N CD
Sbjct: 473 GLGSKNE-----DPCFGPCI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCD-------- 516
Query: 2033 CDPHSGHCLCKAGVTGRRCDRCQEGHFGF 2061
C C +GV+ +RCQ ++ +
Sbjct: 517 ------ECFC-SGVS----NRCQSSYWTY 534
Score = 116 bits (290), Expect = 5e-25
Identities = 67/219 (30%), Positives = 88/219 (40%), Gaps = 48/219 (21%)
Query: 604 RCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA-------------- 639
RC C+ G CD+C PG+H P C+AC C +
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 640 ---LDQLCGAGGLCRCRPGYTGTACQECSPGFH-------GFPS-CVPCHCSAEGSLHAA 688
+ G G C G C+ C+ GF +P C PCHC GSL+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 689 C--DPRS-------GQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPE 739
C D + G C C+ G+ CD C G +P C+A +C G DP
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFG- 484
Query: 740 AQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
PC+C+ +VEG C RCK GF+ L N +GC C C
Sbjct: 485 ---PCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 113 bits (283), Expect = 3e-24
Identities = 68/188 (36%), Positives = 85/188 (45%), Gaps = 39/188 (20%)
Query: 512 VGRCLCKPNFQGTHCELCAPGFY-----------GP---GCQPCQCSSPGVADDRCDPDT 557
+ +C C + G CE C PGFY GP C PCQC+ CDP+T
Sbjct: 1377 IEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG---HSSLCDPET 1433
Query: 558 GQCR-CRVGFEGATCDRCAPGYFHFPL-----CQLCGC---------SPAGTLPEGCDEA 602
C+ C+ G C+RCA GY+ CQ C C SP+ + EG D+
Sbjct: 1434 SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPS-CVAEGLDDY 1492
Query: 603 GRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTCDPRGALDQLCG-AGGLCRCRPGY 656
C + G +C+RC PGY G P +CQ C CDP G+L C G C CRPG
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 657 TGTACQEC 664
TG C C
Sbjct: 1553 TGRKCDGC 1560
Score = 110 bits (276), Expect = 2e-23
Identities = 66/185 (35%), Positives = 85/185 (45%), Gaps = 36/185 (19%)
Query: 559 QCRCRVGFEGATCDRCAPGYFHFP-------------LCQLCGCSPAGTLPEGCD-EAGR 604
+C C +G+ G +C+ C PG++ C C C+ +L CD E
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSI 1435
Query: 605 CL-CQPEFAGPHCDRCRPGYHGF----PN-CQACTCDPRGALDQL---CGAGGL-----C 650
C CQ AG C+RC GY+G PN CQ C C + + C A GL
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 651 RCRPGYTGTACQECSPGFHGFP-----SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGL 705
C GY G C+ C+PG+ G P SC C C GSL CDP +G C+CRP TG
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 706 RCDTC 710
+CD C
Sbjct: 1556 KCDGC 1560
Score = 108 bits (270), Expect = 1e-22
Identities = 73/247 (29%), Positives = 98/247 (39%), Gaps = 52/247 (21%)
Query: 1915 CPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLG-----SSCQPC 1969
CPL +N +++C C+ G SC++C PGF P G + C+ C
Sbjct: 296 CPLDPATN-----------KSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC 344
Query: 1970 DCSGNG-----DPNLLFSDCDPLT-------GACRGCLRHTTGPRCEICAPGFYG----N 2013
+C G D N+ + G C C ++T G CE C GF+ +
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404
Query: 2014 ALLPGNCTRCDCTPCGT--EAC---DPHS------GHCLCKAGVTGRRCDRCQEGHFGFD 2062
P C C C P G+ E C + H+ G C CK G G CDRC G+ G+
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Query: 2063 GCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRCQC 2119
C C G E P G C C+ G C C G++ L E +GC C C
Sbjct: 465 DCKACNCSGLGSKNE----DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Query: 2120 PG--GRC 2124
G RC
Sbjct: 521 SGVSNRC 527
Score = 108 bits (269), Expect = 1e-22
Identities = 71/259 (27%), Positives = 101/259 (38%), Gaps = 62/259 (23%)
Query: 321 QCTCQHNTCGGTCDRCCPG-FNQQPWKPATANSANECQSCNCYGHAT---------DCYY 370
QC C+ N G CD+C G F Q SA C CNC + C+
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQ--------SARGCVPCNCNSFGSKSFDCEESGQCWC 987
Query: 371 DPEVDRRRASQSLDGTY---QGGGVCIDCQH----------------HTTGVNCERCLPG 411
P V ++ + G + +GG +C H +T G C +C P
Sbjct: 988 QPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPN 1047
Query: 412 FYRSPNHPLDSPHVCRRCNCES-DFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPS 470
+ H + + C+ CNC + D C TG+C C P FSG +C C+ G +P
Sbjct: 1048 TW---GHSITTG--CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR 1102
Query: 471 CYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCA 530
C + + LP CD ++ C + G+C CK N +G HC+ C
Sbjct: 1103 C--------NLCDCFLPGTDATTCD-----SETKKCSCSDQTGQCTCKVNVEGIHCDRCR 1149
Query: 531 PGFYG------PGCQPCQC 543
PG +G GC C C
Sbjct: 1150 PGKFGLDAKNPLGCSSCYC 1168
Score = 107 bits (266), Expect = 3e-22
Identities = 70/233 (30%), Positives = 90/233 (38%), Gaps = 62/233 (26%)
Query: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQ-IVNCDCSAAGTQGN 504
RC C N G+ CD C GF ++ AG + +C A G
Sbjct: 306 RCECEHNTCGDSCDQCCPGF----------------HQKPWRAGTFLTKTECEACNCHGK 349
Query: 505 A--CRKDPRVGR----------------CL-CKPNFQGTHCELCAPGFYGPG-------- 537
A C D V R C+ C N G +CE C GF+ P
Sbjct: 350 AEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPR 409
Query: 538 -CQPCQCSSPGVADDRCDPDT---------GQCRCRVGFEGATCDRCAPGYFHFPLCQLC 587
CQPC C G ++ C D G C C+ GF G +CDRCA GY +P C+ C
Sbjct: 410 PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKAC 469
Query: 588 GCSPAGTLPEG-CDEAGRCLCQPEFAGPHCDRCRPGY-----HGFPNCQACTC 634
CS G+ E C G C+C+ G C RC+ G+ + C C C
Sbjct: 470 NCSGLGSKNEDPC--FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 100 bits (250), Expect = 2e-20
Identities = 62/189 (32%), Positives = 79/189 (41%), Gaps = 33/189 (17%)
Query: 650 CRCRPGYTGTACQECSPGFHGFPS-------------CVPCHCSAEGSLHAACDPRSGQC 696
C C GY+G +C+ C PGF+ S CVPC C+ SL CDP + C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL---CDPETSIC 1436
Query: 697 -SCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCM---------- 745
+C+ G C+ C G Y C P+ + C+
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCA-CPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 746 -CRAHVEGPSCDRCKPGFWGLSPSNPEG-CTRCSCDLRGTLGGVAECQPGTGQCFCKPHV 803
C EG C+RC PG+ G SP NP G C C CD G+L C P TG C C+P
Sbjct: 1496 ACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGSLP--VPCDPVTGFCTCRPGA 1552
Query: 804 CGQACASCK 812
G+ C CK
Sbjct: 1553 TGRKCDGCK 1561
Score = 99.8 bits (247), Expect = 5e-20
Identities = 69/217 (31%), Positives = 94/217 (43%), Gaps = 31/217 (14%)
Query: 395 DCQHHTTGVNCERCLPGFYRSPNHP---LDSPHVCRRCNCESDFTDGTCEDLTGRCY-CR 450
DC +G++CE CLPGFYR + P P + C+ + C+ T C C+
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ 1440
Query: 451 PNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP---AGQIVNCDCSAAGTQGNACR 507
+ +G+ C+ CA G+ G P ND ++ P + + C A G C
Sbjct: 1441 HHTAGDFCERCALGYYGIVKGLP-----NDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 508 KDPRVGRCLCKPNFQGTHCELCAPGFYG----PG--CQPCQCSSPGVADDRCDPDTGQCR 561
PR ++G +CE CAPG+ G PG CQ C+C G CDP TG C
Sbjct: 1496 ACPR--------GYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCT 1547
Query: 562 CRVGFEGATCDRCAPGYFHFP---LCQLCGCSPAGTL 595
CR G G CD C ++H C CG G L
Sbjct: 1548 CRPGATGRKCDGCK--HWHAREGWECVFCGDECTGLL 1582
Score = 98.6 bits (244), Expect = 1e-19
Identities = 68/231 (29%), Positives = 87/231 (37%), Gaps = 59/231 (25%)
Query: 505 ACRKDPRVG--RCLCKPNFQGTHCELCAPGFYGPG-----------CQPCQCSSPGVADD 551
AC DP RC C+ N G C+ C PGF+ C+ C C +
Sbjct: 295 ACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKA---E 351
Query: 552 RCDPDTGQCR-------------------CRVGFEGATCDRCAPGYF-------HFPL-C 584
C D R C G C+ C G+F ++P C
Sbjct: 352 ECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPC 411
Query: 585 QLCGCSPAGTLPEGC--DEA--------GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTC 634
Q C C P G+L E C DE G C C+ F G CDRC GY G+P+C+AC C
Sbjct: 412 QPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC 471
Query: 635 DPRGALDQLCGAGGLCRCRPGYTGTACQECSPGF-----HGFPSCVPCHCS 680
G+ ++ G C C+ G C C GF + C C CS
Sbjct: 472 SGLGSKNE-DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 97.4 bits (241), Expect = 2e-19
Identities = 68/200 (34%), Positives = 84/200 (42%), Gaps = 34/200 (17%)
Query: 442 DLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGT 501
DL +C C +SG C+ C GF S P + T G V C C+
Sbjct: 1375 DLIEKCDCPLGYSGLSCEACLPGFYRLRS-QPGGRTPGPT------LGTCVPCQCN---- 1423
Query: 502 QGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG------PGCQPCQCS--------SP 546
G++ DP C C+ + G CE CA G+YG CQ C C SP
Sbjct: 1424 -GHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSP 1482
Query: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAGTLPEGCDE 601
+ D D C G+EG C+RCAPGY P CQ C C P G+LP CD
Sbjct: 1483 SCVAEGLD-DYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDP 1541
Query: 602 -AGRCLCQPEFAGPHCDRCR 620
G C C+P G CD C+
Sbjct: 1542 VTGFCTCRPGATGRKCDGCK 1561
Score = 95.5 bits (236), Expect = 9e-19
Identities = 65/220 (29%), Positives = 88/220 (40%), Gaps = 49/220 (22%)
Query: 321 QCTCQHNTCGGTCDRCCPGF---NQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRR 377
+C C G +C+ C PGF QP + C C C GH++ C DPE
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC--DPETS-- 1434
Query: 378 RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC-----E 432
+C +CQHHT G CERC G+Y P+ C++C C
Sbjct: 1435 --------------ICQNCQHHTAGDFCERCALGYYGIVK---GLPNDCQQCACPLISSS 1477
Query: 433 SDFTDG-TCEDLTG-RC-YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAG 489
++F+ E L RC C + G+ C+ CA G+TG P P G
Sbjct: 1478 NNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG---------------NPGG 1522
Query: 490 QIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
C+C G+ C DP G C C+P G C+ C
Sbjct: 1523 SCQECECDPYGSLPVPC--DPVTGFCTCRPGATGRKCDGC 1560
Score = 92.0 bits (227), Expect = 1e-17
Identities = 54/179 (30%), Positives = 72/179 (40%), Gaps = 14/179 (7%)
Query: 695 QCSCRPRVTGLRCDTCVPGAYNF--------PYCEAGSCHPAGLAPVDPAL-PEAQVPCM 745
+C C +GL C+ C+PG Y P G+C P PE +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 746 CRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGG-----VAECQPGTGQCFCK 800
C+ H G C+RC G++G+ P C +C+C L + VAE C
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 801 PHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
GQ C C G+ G C+ C CD G+L C+P TG C CRP G C
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKC 1557
Score = 90.1 bits (222), Expect = 4e-17
Identities = 70/247 (28%), Positives = 92/247 (37%), Gaps = 57/247 (23%)
Query: 626 FPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFP----------SCV 675
+ + +AC DP + C C G +C +C PGFH P C
Sbjct: 290 YGHARACPLDPATNKSR-------CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECE 342
Query: 676 PCHC--SAEGSLHAACDPR-------------SGQC-SCRPRVTGLRCDTCVPGAY---- 715
C+C AE + R G C +C G+ C+TC G +
Sbjct: 343 ACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKG 402
Query: 716 ---NFPY-CEAGSCHPAGLAPVDPALPE-------AQVPCMCRAHVEGPSCDRCKPGFWG 764
N+P C+ C P G E A C C+ G SCDRC G+ G
Sbjct: 403 VSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG 462
Query: 765 LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYF 824
C C+C LG E P G C CK +V G C+ CK GFF L + ++
Sbjct: 463 YPD-----CKACNCS---GLGSKNE-DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWK 513
Query: 825 GCRSCRC 831
GC C C
Sbjct: 514 GCDECFC 520
Score = 85.5 bits (210), Expect = 9e-16
Identities = 51/163 (31%), Positives = 73/163 (44%), Gaps = 23/163 (14%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
C C+GH+ CD + + CQH+T G C+RC G+ N+CQ C
Sbjct: 1420 CQCNGHSSLCDPET-----SICQNCQHHTAGDFCERCALGY-----YGIVKGLPNDCQQC 1469
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
C ++ + P ++ LD Y+ C C G CERC PG+ SP +P
Sbjct: 1470 ACPLISSSNNFSPSC----VAEGLD-DYR----CTACPRGYEGQYCERCAPGYTGSPGNP 1520
Query: 420 LDSPHVCRRCNCES-DFTDGTCEDLTGRCYCRPNFSGERCDVC 461
S C+ C C+ C+ +TG C CRP +G +CD C
Sbjct: 1521 GGS---CQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 78.6 bits (192), Expect = 1e-13
Identities = 57/200 (28%), Positives = 80/200 (40%), Gaps = 41/200 (20%)
Query: 695 QCSCRPRVTGLRCDTCVPGAYNFPY----------CEAGSCH-PAGLAPVDPALPEAQVP 743
+C C G CD C PG + P+ CEA +CH A D + +
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 744 ------------CM-CRAHVEGPSCDRCKPGFW---GLSPSNPEGCTRCSCDLRGTLGGV 787
C+ C + G +C+ C GF+ G+SP+ P C C CD G+L V
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 788 -------AECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS 840
A G C CK G +C C G+ G Y C++C C G+ +
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG-----YPDCKACNCSGLGSKNE- 479
Query: 841 CEPRTGVCRCRPNTQGPTCS 860
+P G C C+ N +G CS
Sbjct: 480 -DPCFGPCICKENVEGGDCS 498
Score = 71.2 bits (173), Expect = 2e-11
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 14/116 (12%)
Query: 1431 YNNGARPCGCHEVGATGPTCEP---------FGGQCPCHAHVIGRDCSRCATGYWGFPNC 1481
Y +PC C +G+ C G C C G C RCA GY G+P+C
Sbjct: 407 YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDC 466
Query: 1482 RPCDC---GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHP--LVGCEECNCSG 1532
+ C+C G++ D G CIC DC C+ F GC+EC CSG
Sbjct: 467 KACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSG 522
Score = 62.4 bits (150), Expect = 8e-09
Identities = 49/189 (25%), Positives = 62/189 (32%), Gaps = 47/189 (24%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
C C + CD K +C C NT G C +C P W + C++C
Sbjct: 1014 CECSHLGNNCDPKTG------RCICPPNTIGEKCSKCAP----NTWGHSITTG---CKAC 1060
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
NC SLD +C +G C C G + P
Sbjct: 1061 NC----------------STVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR-- 1102
Query: 420 LDSPHVCRRCNCESDFTDGT----------CEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
C C+C TD T C D TG+C C+ N G CD C G G
Sbjct: 1103 ------CNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLD 1156
Query: 470 SCYPTPSSS 478
+ P SS
Sbjct: 1157 AKNPLGCSS 1165
Score = 50.4 bits (119), Expect = 3e-05
Identities = 36/138 (26%), Positives = 45/138 (32%), Gaps = 43/138 (31%)
Query: 1528 CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP----------RCRPC 1577
C C G DP T+ +C+C N G CD C PGFH P C C
Sbjct: 287 CICYGHARACPLDPA--TNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC 344
Query: 1578 DCHEAG----------------------TAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1615
+CH GVC C +N G C+ C+ G F
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVC------INCTQNTAGINCETCTDGFF 398
Query: 1616 ---SLDAANPKGCTRCFC 1630
+ P+ C C C
Sbjct: 399 RPKGVSPNYPRPCQPCHC 416
Score = 43.9 bits (102), Expect = 0.003
Identities = 36/125 (28%), Positives = 47/125 (37%), Gaps = 19/125 (15%)
Query: 1399 DFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCP 1458
DF CA GY+ C+ A L NN + C + T P G +
Sbjct: 1446 DFCERCAL-GYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE-- 1502
Query: 1459 CHAHVIGRDCSRCATGYWGFP-----NCRPCDCGAR-----LCDELTGQCICPPRTIPPD 1508
G+ C RCA GY G P +C+ C+C CD +TG C C P
Sbjct: 1503 ------GQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 1509 CLLCQ 1513
C C+
Sbjct: 1557 CDGCK 1561
Score = 43.5 bits (101), Expect = 0.004
Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%)
Query: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPG-FNQQPWKPATANSANECQSCN 360
C C D T QCTC+ N G CDRC PG F P C SC
Sbjct: 1118 CDSETKKCSCSDQTG----QCTCKVNVEGIHCDRCRPGKFGLDAKNPL------GCSSCY 1167
Query: 361 CYGHATDC 368
C+G T C
Sbjct: 1168 CFGTTTQC 1175
Score = 39.7 bits (91), Expect = 0.056
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 1436 RPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELT 1495
+ C C +G+ +P G C C +V G DCSRC +G++ C C ++
Sbjct: 467 KACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVS 524
Query: 1496 GQC 1498
+C
Sbjct: 525 NRC 527
Score = 38.9 bits (89), Expect = 0.096
Identities = 35/135 (25%), Positives = 45/135 (33%), Gaps = 38/135 (28%)
Query: 2065 GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGY----WG----LPEQGCRR 2116
G R C PA S +C C T G C +C PG+ W L + C
Sbjct: 291 GHARACPLDPATNKS-------RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 2117 CQCPG--GRC--DPHTGR-----------------CNCPPGLSGERCDTCSQQHQVPVPG 2155
C C G C D + R NC +G C+TC+ P
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGV 403
Query: 2156 GPVGHSIHCEVCDHC 2170
P + C+ C HC
Sbjct: 404 SP-NYPRPCQPC-HC 416
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 402 bits (1032), Expect = e-111
Identities = 372/1343 (27%), Positives = 567/1343 (42%), Gaps = 217/1343 (16%)
Query: 1457 CPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGARLCD-----ELT------ 1495
C C + G DC +C + P C PCDC R + EL
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364
Query: 1496 GQCI-CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
G C C T C C+ F C C+CS G CD+ G+C C+P
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGS---LSTQCDS-YGRCSCKP 420
Query: 1555 NVTGRRCDTCSPGFHGYPR--CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
V G +CD C PGFH CRPC C +G+ C+ TG+C CK+NV+G C++C
Sbjct: 421 GVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKP 479
Query: 1613 GTFSLDAANPKGCTRCFCFGATERCRSS------SYTRQEFVDMEGWVLLSTDRQVVPHE 1666
G F+L+++NP+GCT CFCFG + C ++ S + +D +GW E
Sbjct: 480 GFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGW----------RAE 529
Query: 1667 RQPGTE--MLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGD 1724
++ G+E + + R + +++ Y+ AP +LG +V SYG L + R D
Sbjct: 530 QRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSF--RVDRRD 587
Query: 1725 VFVPMESRPDVVLQGN--QMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTET-----RNT 1777
+ E D+VL+G ++S+ + P V+ FR E R
Sbjct: 588 TRLSAE---DLVLEGAGLRVSVPLIAQGNSYPSET------TVKYVFRLHEATDYPWRPA 638
Query: 1778 VSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPASY 1837
++ E +L +L ++IR +S+ SA +L V L A P G G A+ VE C CP Y
Sbjct: 639 LTPFEFQKLLNNLTSIKIRGTYSE-RSAGYLDDVTLASARP-GPGVPATWVESCTCPVGY 696
Query: 1838 RGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQ 1896
G C+ C G+ R+ L CV C C+GHS+ C P +GVC +C+ NT G HCE+C
Sbjct: 697 GGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCS 755
Query: 1897 AGFV-SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKPGYAGASCERCAPG 1954
G+ S S+ C CPCP + V + C C G G CE C G
Sbjct: 756 DGYYGDSTAGTSSDCQPCPCP-----GGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDG 810
Query: 1955 FFGNPLVLGSS---CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+FG+PL C+ C CS N DPN + +C+ LTG C C+ +T G C+ C GF+
Sbjct: 811 YFGDPLGRNGPVRLCRLCQCSDNIDPNAV-GNCNRLTGECLKCIYNTAGFYCDRCKDGFF 869
Query: 2012 GNALLPG---NCTRCDCTPCGT----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGC 2064
GN L P C C+C GT +C+P +G C C VTG+ C C G +
Sbjct: 870 GNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSG 929
Query: 2065 GGCRPCAC-GPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-PGG 2122
GC C C + +C ++GQC C+PG G C C ++G +GC+ C C P G
Sbjct: 930 QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEG 989
Query: 2123 RCD---PHTGRCNCPPGLSGERCDTCSQQ--HQVPVPGGPVGHSIHCEVCDHCVVLLLDD 2177
GRC C G G RCD C + + PG C+ C C L+ D
Sbjct: 990 SLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPG--------CQECPACYRLVKDK 1041
Query: 2178 LERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLE 2237
+ A H +L L + IA+L + G T Q E
Sbjct: 1042 V--------ADHR------------VKLQELESLIANLGT------GDEMVTDQAFEDRL 1075
Query: 2238 QQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTG 2297
+++ D R +A +D L+ + + ++ ++ + T+ E TG
Sbjct: 1076 KEAEREVMDLLR---EAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE----TG 1128
Query: 2298 HLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLS 2357
+L EQ + ERL+ E+ +R+L + AA A ++ Q ++
Sbjct: 1129 NL---------AEQARAHVENTERLI-EIASRELEKAKVAA-ANVSVTQPESTGDPNNMT 1177
Query: 2358 SLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSR-----NQERLE-E 2411
L EE + LA +H+ D+ A D + EA L R NQ E E
Sbjct: 1178 LLAEEARKLA-------ERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIE 1230
Query: 2412 ALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQR 2471
L RK E ++ + ++D R+ +A ++ + AS
Sbjct: 1231 ELNRKYEQAK---------NISQDLEKQAARVHEEAKRAGDKAVEIYAS----------- 1270
Query: 2472 MQTFSPAGSKLRLVEA--AEAHAQQLGQLALNLSSIILDVNQD---------RLTQRAIE 2520
+ SP S+ EA + A+ L QL D+ +D L ++
Sbjct: 1271 VAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKT 1330
Query: 2521 ASNAYSRILQAVQAAEDAAGQALQQADHTW--ATVVRQGLVDRAQQLLANSTALEEAMLQ 2578
++L AA+ A +A ++ T A + L D +++ N TA EEA+
Sbjct: 1331 EQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEAL-- 1388
Query: 2579 EQQRLGLVWAALQGARTQLRDVR-----AKKDQLEAHIQAAQA---MLAMDTDETSKKIA 2630
+++ + + A + R+ + A D EA +A +A A+ + TS K A
Sbjct: 1389 --RKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTK-A 1445
Query: 2631 HAKAVAAEAQDTATRVQSQLQAMQE---NVERWQGQYE------GLRGQDLGQAVLD--- 2678
A+ AE D V + L+ +QE ++R Q + G+ Q +A ++
Sbjct: 1446 EAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARK 1505
Query: 2679 AGHSVSTLEKTLPQLLAKLSILE 2701
A +SV++L + LL +L L+
Sbjct: 1506 AKNSVTSLLSIINDLLEQLGQLD 1528
Score = 301 bits (772), Expect = 6e-81
Identities = 184/553 (33%), Positives = 264/553 (47%), Gaps = 78/553 (14%)
Query: 7 AGSALCVRGPRGPAPLLLVGLALLGAARAR-----EEAGGGFSLHPPYFNLAEGARIAAS 61
A AL RG P +L A G A+A +E G P + N A + A+
Sbjct: 7 AAPALRPRGRLWPVLAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNVTVVAT 66
Query: 62 ATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAI 121
TCG P E+ YC G V G + C +C A + H A+
Sbjct: 67 NTCGT---------PPEE-YCVQTG--VTGVTKS-------CHLCDAGQPHLQHGAAFLT 107
Query: 122 DGTER----WWQSPPLSRGLEY-NEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSM 176
D + WWQS + G++Y + +N+TL LG+ F + YV +KF S + +R+
Sbjct: 108 DYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTR 167
Query: 177 DFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVN 236
+ G + P+Q+++ S + + + + A+CT E+S I PL G + S +
Sbjct: 168 EDG-PWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLE 226
Query: 237 GRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISI 296
GRP A NF SP+L+E+ AT++R+ R NT + DP V + YYY+I D ++
Sbjct: 227 GRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTF----GDEVFNDPKVLKSYYYAISDFAV 282
Query: 297 GGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANEC 356
GGRC C+GHA C K+ D +L C C+HNT G C++C P FN +PW+ ATA SA+EC
Sbjct: 283 GGRCKCNGHASEC-MKNEFD--KLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASEC 339
Query: 357 QSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSP 416
C+C G + +CY+DPE+ R GG C +CQ +T G +CERC F+R
Sbjct: 340 LPCDCNGRSQECYFDPELYRSTGH---------GGHCTNCQDNTDGAHCERCRENFFRLG 390
Query: 417 NHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPS 476
N+ C C+C + T D GRC C+P G++CD C GF P
Sbjct: 391 NN-----EACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 445
Query: 477 SSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG- 535
S + P+G I C+ GRC+CK N +G +CE C PGF+
Sbjct: 446 SCD-------PSGSIDECNI--------------ETGRCVCKDNVEGFNCERCKPGFFNL 484
Query: 536 -----PGCQPCQC 543
GC PC C
Sbjct: 485 ESSNPRGCTPCFC 497
Score = 205 bits (521), Expect = 8e-52
Identities = 114/346 (32%), Positives = 157/346 (45%), Gaps = 51/346 (14%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
C C+GH++ CD + C C+ NT G C++C G+ + +TA ++++CQ C
Sbjct: 724 CACNGHSETCDPETGV------CNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQPC 773
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
C G + C P+ VC +C TTG CE C G++ P
Sbjct: 774 PCPG-GSSCAVVPKTKEV--------------VCTNCPTGTTGKRCELCDDGYFGDPLGR 818
Query: 420 LDSPHVCRRCNCESDFTD---GTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTP 475
+CR C C + G C LTG C C N +G CD C +GF G P
Sbjct: 819 NGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFG------NP 872
Query: 476 SSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY- 534
+ N PA + C+C+ GT +P G+C C P+ G C C PGFY
Sbjct: 873 LAPN-------PADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 535 ---GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF--PLCQLCGC 589
G GC+ C C + G + +CD TGQC C+ G G C+RC +F F C+ C C
Sbjct: 926 LQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDC 985
Query: 590 SPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGY---HGFPNCQAC 632
P G+L C + GRC C+ F G CD+C Y +P CQ C
Sbjct: 986 HPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 179 bits (454), Expect = 5e-44
Identities = 122/380 (32%), Positives = 161/380 (42%), Gaps = 62/380 (16%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C + G+ C++C G+ TP+ P V C C+ G++
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRR-----ETPNLG--------PYSPCVLCACN-----GHSE 731
Query: 507 RKDPRVGRCLCKPNFQGTHCELCAPGFYGPG-------CQPCQCSSPGVADDRCDPDTGQ 559
DP G C C+ N G HCE C+ G+YG CQPC C PG + P T +
Sbjct: 732 TCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPC--PGGSSCAVVPKTKE 789
Query: 560 C---RCRVGFEGATCDRCAPGYFHFPL--------CQLCGCSPA--GTLPEGCDE-AGRC 605
C G G C+ C GYF PL C+LC CS C+ G C
Sbjct: 790 VVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGEC 849
Query: 606 L-CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAG---GLCRCRP 654
L C AG +CDRC+ G+ G P C+AC C+ G + Q G C C P
Sbjct: 850 LKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLP 909
Query: 655 GYTGTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCV 711
TG C C PGF+ S C C C A GS + CD R+GQC C+P +TG C+ C
Sbjct: 910 HVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCE 969
Query: 712 PGAYNF--PYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSN 769
+ F C+ CHP G + + C CR G CD+C+ ++ + S
Sbjct: 970 VNHFGFGPEGCKPCDCHPEGSLSLQ---CKDDGRCECREGFVGNRCDQCEENYF-YNRSW 1025
Query: 770 PEGCTRCSCDLRGTLGGVAE 789
P GC C R VA+
Sbjct: 1026 P-GCQECPACYRLVKDKVAD 1044
Score = 167 bits (424), Expect = 1e-40
Identities = 108/343 (31%), Positives = 145/343 (42%), Gaps = 47/343 (13%)
Query: 560 CRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEF 611
C C VG+ G C+ C GY + C LC C+ E CD E G C C+
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS---ETCDPETGVCNCRDNT 746
Query: 612 AGPHCDRCRPGYHG------FPNCQACTCDPRGALDQLCGAGG--LC-RCRPGYTGTACQ 662
AGPHC++C GY+G +CQ C C P G+ + +C C G TG C+
Sbjct: 747 AGPHCEKCSDGYYGDSTAGTSSDCQPCPC-PGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 663 ECSPGFHGFPS--------CVPCHCSAEGSLHAA--CDPRSGQC-SCRPRVTGLRCDTCV 711
C G+ G P C C CS +A C+ +G+C C G CD C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Query: 712 PGAYNFPY-------CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWG 764
G + P C+A +C+ G + C C HV G C C PGF+
Sbjct: 866 DGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 765 LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYF 824
L +GC RC C G+ G +C TGQC C+P + GQ C C+ FG
Sbjct: 926 LQSG--QGCERCDCHALGSTNG--QCDIRTGQCECQPGITGQHCERCEVNHFGFGPE--- 978
Query: 825 GCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
GC+ C C G+L C+ G C CR G C + +++
Sbjct: 979 GCKPCDCHPEGSLSLQCKD-DGRCECREGFVGNRCDQCEENYF 1020
Score = 162 bits (411), Expect = 4e-39
Identities = 107/360 (29%), Positives = 147/360 (40%), Gaps = 57/360 (15%)
Query: 512 VGRCLCKPNFQGTHCELCAPGF---------YGPGCQPCQCSSPGVADDRCDPDTGQCRC 562
V C C + G CE+C G+ Y P C C C+ + CDP+TG C C
Sbjct: 687 VESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSP-CVLCACNG---HSETCDPETGVCNC 742
Query: 563 RVGFEGATCDRCAPGYFHFPL------CQLCGC---SPAGTLPEGCDEAGRCLCQPEFAG 613
R G C++C+ GY+ CQ C C S +P+ E C G
Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPK-TKEVVCTNCPTGTTG 801
Query: 614 PHCDRCRPGYHGFP--------NCQACTC----DPRGALDQLCGAGGLCRCRPGYTGTAC 661
C+ C GY G P C+ C C DP + G +C G C
Sbjct: 802 KRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYC 861
Query: 662 QECSPGFHGFP-------SCVPCHCSAEGSL--HAACDPRSGQCSCRPRVTGLRCDTCVP 712
C GF G P C C+C+ G++ ++C+P +GQC C P VTG C C P
Sbjct: 862 DRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDP 921
Query: 713 GAYNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSN 769
G YN CE CH G + Q C C+ + G C+RC+ +G
Sbjct: 922 GFYNLQSGQGCERCDCHALGSTNGQCDIRTGQ--CECQPGITGQHCERCEVNHFGF---G 976
Query: 770 PEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSC 829
PEGC C C G+L +C+ G+C C+ G C C++ +F + GC+ C
Sbjct: 977 PEGCKPCDCHPEGSLS--LQCK-DDGRCECREGFVGNRCDQCEENYF--YNRSWPGCQEC 1031
Score = 131 bits (330), Expect = 1e-29
Identities = 74/223 (33%), Positives = 95/223 (42%), Gaps = 36/223 (16%)
Query: 494 CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY-----------GPGCQPCQ 542
C C+ ++ D V C CK N G CE C P F C PC
Sbjct: 286 CKCNGHASECMKNEFDKLV--CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCD 343
Query: 543 CSSPGVADDRC--DPDT-------GQC-RCRVGFEGATCDRCAPGYFHF---PLCQLCGC 589
C+ C DP+ G C C+ +GA C+RC +F C C C
Sbjct: 344 CNG---RSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHC 400
Query: 590 SPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGF--PNCQACTCDPRGALDQLCGAG 647
SP G+L CD GRC C+P G CDRC+PG+H C+ C+CDP G++D+
Sbjct: 401 SPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIET 460
Query: 648 GLCRCRPGYTGTACQECSPGFHGFPS-----CVPCHCSAEGSL 685
G C C+ G C+ C PGF S C PC C S+
Sbjct: 461 GRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSV 503
Score = 124 bits (311), Expect = 2e-27
Identities = 80/247 (32%), Positives = 109/247 (44%), Gaps = 44/247 (17%)
Query: 541 CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD 600
C+C+ + + D C C+ G C++C P + P + S + LP CD
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLP--CD 343
Query: 601 EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC-RCRPGYTGT 659
GR Q C DP L + G GG C C+ G
Sbjct: 344 CNGRS------------------------QECYFDPE--LYRSTGHGGHCTNCQDNTDGA 377
Query: 660 ACQECSPGFHGF---PSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYN 716
C+ C F +C CHCS GSL CD G+CSC+P V G +CD C PG ++
Sbjct: 378 HCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHS 436
Query: 717 FPY--CEAGSCHPAGLAPVDPALPEAQVP---CMCRAHVEGPSCDRCKPGFWGLSPSNPE 771
C SC P+G ++ E + C+C+ +VEG +C+RCKPGF+ L SNP
Sbjct: 437 LTEAGCRPCSCDPSG------SIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPR 490
Query: 772 GCTRCSC 778
GCT C C
Sbjct: 491 GCTPCFC 497
Score = 122 bits (306), Expect = 7e-27
Identities = 72/210 (34%), Positives = 96/210 (45%), Gaps = 30/210 (14%)
Query: 1830 LCLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRC---------LPG 1876
+C C + G C++C P F +R C+PC C+G S C
Sbjct: 304 VCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGH 363
Query: 1877 SGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQ 1936
G C +CQ NT+GAHCERC+ F R + C SC C P + + C G +
Sbjct: 364 GGHCTNCQDNTDGAHCERCRENFF--RLGNNEACSSCHCS---PVGSLSTQCDSYG---R 415
Query: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLR 1996
C CKPG G C+RC PGF + + C+PC C DP+ +C+ TG C C
Sbjct: 416 CSCKPGVMGDKCDRCQPGFHS---LTEAGCRPCSC----DPSGSIDECNIETGRC-VCKD 467
Query: 1997 HTTGPRCEICAPGFYG-NALLPGNCTRCDC 2025
+ G CE C PGF+ + P CT C C
Sbjct: 468 NVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 117 bits (292), Expect = 3e-25
Identities = 76/270 (28%), Positives = 105/270 (38%), Gaps = 80/270 (29%)
Query: 1437 PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWG------FPNCRPCDC---- 1486
PC TC+P G C C + G C +C+ GY+G +C+PC C
Sbjct: 720 PCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGS 779
Query: 1487 ---------------------GAR--LCDE------------------------------ 1493
G R LCD+
Sbjct: 780 SCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAV 839
Query: 1494 -----LTGQCI-CPPRTIPPDCLLCQPQTFG----CHPLVGCEECNCSGPGIQELTDPTC 1543
LTG+C+ C T C C+ FG +P C+ CNC+ G + +C
Sbjct: 840 GNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMK-QQSSC 898
Query: 1544 DTDSGQCKCRPNVTGRRCDTCSPGFHGYPR---CRPCDCHEAGTAPGVCDPLTGQCYCKE 1600
+ +GQC+C P+VTG+ C C PGF+ C CDCH G+ G CD TGQC C+
Sbjct: 899 NPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQP 958
Query: 1601 NVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
+ G C++C + F P+GC C C
Sbjct: 959 GITGQHCERCEVNHFGF---GPEGCKPCDC 985
Score = 115 bits (289), Expect = 6e-25
Identities = 72/229 (31%), Positives = 102/229 (44%), Gaps = 37/229 (16%)
Query: 1864 CQCHGHSDRCLPG--SGVCVDCQHNTEGAHCERCQAGFVS-----SRDDPSAPCVSCPCP 1916
C+C+GH+ C+ + +C+HNT G CE+C F + + ++ C+ C C
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC- 344
Query: 1917 LSVPSNNFAEGCVL-------RGGRTQCL-CKPGYAGASCERCAPGFF--GNPLVLGSSC 1966
N ++ C G C C+ GA CERC FF GN +C
Sbjct: 345 -----NGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEAC 395
Query: 1967 QPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCT 2026
C CS G L + CD G C C G +C+ C PGF+ +L C C C
Sbjct: 396 SSCHCSPVGS---LSTQCDSY-GRC-SCKPGVMGDKCDRCQPGFH--SLTEAGCRPCSCD 448
Query: 2027 PCGT-EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG--GCRPCAC 2072
P G+ + C+ +G C+CK V G C+RC+ G F + GC PC C
Sbjct: 449 PSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 113 bits (283), Expect = 3e-24
Identities = 66/196 (33%), Positives = 83/196 (42%), Gaps = 23/196 (11%)
Query: 1969 CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY------GNALLPGNCTR 2022
C C+G+ + ++ D L C+ +T G CE C P F A C
Sbjct: 286 CKCNGHAS-ECMKNEFDKLVCNCK---HNTYGVDCEKCLPFFNDRPWRRATAESASECLP 341
Query: 2023 CDCTPCGTEAC-DP-------HSGHCL-CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACG 2073
CDC E DP H GHC C+ G C+RC+E F C C C
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCS 401
Query: 2074 PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-PGG---RCDPHTG 2129
P S G+C C+PG MG +C C PG+ L E GCR C C P G C+ TG
Sbjct: 402 PVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETG 461
Query: 2130 RCNCPPGLSGERCDTC 2145
RC C + G C+ C
Sbjct: 462 RCVCKDNVEGFNCERC 477
Score = 109 bits (273), Expect = 4e-23
Identities = 65/202 (32%), Positives = 92/202 (45%), Gaps = 27/202 (13%)
Query: 649 LCRCRPGYTGTACQECSPGFHGFP----------SCVPCHCSAEGSLHAACDPR------ 692
+C C+ G C++C P F+ P C+PC C+ S DP
Sbjct: 304 VCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGR-SQECYFDPELYRSTG 362
Query: 693 -SGQCS-CRPRVTGLRCDTCVPGAYNFPYCEA-GSCHPAGLAPVDPALPEAQVPCMCRAH 749
G C+ C+ G C+ C + EA SCH + + + ++ C C+
Sbjct: 363 HGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQC-DSYGRCSCKPG 421
Query: 750 VEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA 809
V G CDRC+PGF L+ + GC CSCD G++ EC TG+C CK +V G C
Sbjct: 422 VMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSID---ECNIETGRCVCKDNVEGFNCE 475
Query: 810 SCKDGFFGLDQADYFGCRSCRC 831
CK GFF L+ ++ GC C C
Sbjct: 476 RCKPGFFNLESSNPRGCTPCFC 497
Score = 97.4 bits (241), Expect = 2e-19
Identities = 54/155 (34%), Positives = 69/155 (44%), Gaps = 18/155 (11%)
Query: 1436 RPCGCHEVGATGP--TCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN---CRPCDCGA-- 1488
+ C C+ G +C P GQC C HV G+DC C G++ + C CDC A
Sbjct: 882 KACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALG 941
Query: 1489 ---RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545
CD TGQC C P C C+ FG P GC+ C+C G L C
Sbjct: 942 STNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGP-EGCKPCDCHPEGSLSL---QC-K 996
Query: 1546 DSGQCKCRPNVTGRRCDTCSPGF---HGYPRCRPC 1577
D G+C+CR G RCD C + +P C+ C
Sbjct: 997 DDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 69.7 bits (169), Expect = 5e-11
Identities = 36/109 (33%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 1430 FYN----NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF--PNCRP 1483
FYN G C CH +G+T C+ GQC C + G+ C RC ++GF C+P
Sbjct: 923 FYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKP 982
Query: 1484 CDC----GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEEC 1528
CDC L + G+C C + C C+ F GC+EC
Sbjct: 983 CDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 62.0 bits (149), Expect = 1e-08
Identities = 34/109 (31%), Positives = 45/109 (41%), Gaps = 9/109 (8%)
Query: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF--PNCRPCDC--- 1486
N C C VG+ C+ +G +C C V+G C RC G+ CRPC C
Sbjct: 392 NEACSSCHCSPVGSLSTQCDSYG-RCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPS 450
Query: 1487 -GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPL--VGCEECNCSG 1532
C+ TG+C+C +C C+P F GC C C G
Sbjct: 451 GSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFG 499
Score = 45.4 bits (106), Expect = 0.001
Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 1413 PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCA 1472
P + C + F G +PC CH G+ C+ G+C C +G C +C
Sbjct: 958 PGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKD-DGRCECREGFVGNRCDQCE 1016
Query: 1473 TGYW---GFPNCRPCDCGARL 1490
Y+ +P C+ C RL
Sbjct: 1017 ENYFYNRSWPGCQECPACYRL 1037
Score = 41.2 bits (95), Expect = 0.019
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 8/64 (12%)
Query: 308 ACDAKDPTDPFRLQ---CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGH 364
+CD D ++ C C+ N G C+RC PGF +++ C C C+GH
Sbjct: 446 SCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFN-----LESSNPRGCTPCFCFGH 500
Query: 365 ATDC 368
++ C
Sbjct: 501 SSVC 504
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 394 bits (1011), Expect = e-108
Identities = 247/756 (32%), Positives = 351/756 (46%), Gaps = 85/756 (11%)
Query: 113 KAHPASNAID---GTERWWQSPPLSRGLEYNE---VNVTLDLGQVFHVAYVLIKFANSPR 166
+AHP S D GT W S + + N+ ++V L+ GQ + V Y++I+F SP+
Sbjct: 338 EAHPLSFVNDNDVGTS--WVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQ 393
Query: 167 PDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLE 226
P ++R + ++ WQ+FA R+C FG + + + D+ C + S P
Sbjct: 394 PTEIRIQRKKENSLDWEDWQYFA---RNC-GAFGMKNNGDLEKPDSVNCL-QLSNFTPYS 448
Query: 227 NGEIVVSLV----NGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282
G + S++ N RPG NF +P L+EF KAT +R F H
Sbjct: 449 RGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAV 500
Query: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQ 342
R YY++ +I+I GRC CHGHAD CD + P+R C+ + T G CDRC P +N
Sbjct: 501 NLRHRYYAVDEITISGRCQCHGHADNCDTT--SQPYRCLCSQESFTEGLHCDRCLPLYND 558
Query: 343 QPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTG 402
+P++ A C+ C C H+ C+Y+ VD + GGGVC DC+H+TTG
Sbjct: 559 KPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTG 614
Query: 403 VNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDG---TCEDLTGRCYCRPNFSGERCD 459
NCE C F+R + VC+ C+C++ T C+ + G+C C+ + SG +C+
Sbjct: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN 674
Query: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
C GF P S C+C+ +GT G+C CK
Sbjct: 675 QCQNGFYNLQELDPDGCSP---------------CNCNTSGTVDGDITCHQNSGQCKCKA 719
Query: 520 NFQGTHCELCAPG------FYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR 573
N G C+ C G F GC+PCQC+ G + C+P +GQC C+ +G CD
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779
Query: 574 CAPGYFHFPL--CQLCGCSPAGTLP-EGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPN- 628
C ++ + C+ C C AG+LP C+ + G+C+C+P G C++C G
Sbjct: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 629 ----CQACTCDPRGALD--QLCG-AGGLCRCRPGYTGTACQECSP-----GFHGFPSCVP 676
C C CD G ++ LC + G C C+ G TG C +C P F C
Sbjct: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899
Query: 677 CHCSAEGSLHAA-CDPRSGQCSCRPRVTGLRCDTCVPGAY----NFPYCEAGSCHPAGLA 731
C C + G+L CDP SGQC C P G RC+ C PG Y N C SCH G
Sbjct: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTG-- 957
Query: 732 PVDPALPEAQVPCMCR-AHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAEC 790
V+ C+C+ A + G CD+CK ++G P C C+C L G L C
Sbjct: 958 AVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSGALN--ETC 1014
Query: 791 QPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 826
TGQCFCK V G C +C LD + GC
Sbjct: 1015 HLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Score = 288 bits (737), Expect = 7e-77
Identities = 185/617 (29%), Positives = 270/617 (43%), Gaps = 114/617 (18%)
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C+GHA +C + R SQ + T G++C+RCLP + P
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQ---------------ESFTEGLHCDRCLPLYNDKPFR 562
Query: 419 PLDSPHV--CRRCNCESDFTD-------------------GTCEDLTGRCYCRPNFSGER 457
D + C+ C C S G C+D C N +G
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD------CEHNTTGRN 616
Query: 458 CDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLC 517
C++C + F F PS+ + + CDC GT+ + D G+C C
Sbjct: 617 CELCKDYF--FRQVGADPSAIDVCKP----------CDCDTVGTRNGSILCDQIGGQCNC 664
Query: 518 KPNFQGTHCELCAPGFYG------PGCQPCQCSSPGVADD--RCDPDTGQCRCRVGFEGA 569
K + G C C GFY GC PC C++ G D C ++GQC+C+ G
Sbjct: 665 KRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGL 724
Query: 570 TCDRCAPGY-----FHFPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRPGY 623
CD C G+ F+ C+ C C+ G++ + C+ +G+C C+ E G CD CR +
Sbjct: 725 RCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENF 784
Query: 624 HGFP--NCQACTCDPRGALD-QLCGAG-GLCRCRPGYTGTACQECSPGFHGFPS-----C 674
+G NC+AC CD G+L +C A G C C+P G C +C G C
Sbjct: 785 YGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 675 VPCHCSAEGSLHAA--CDPRSGQCSCRPRVTGLRCDTCVPGAYN-----FPYCEAGSCHP 727
+PC+C G+++ + C+ +GQC C+ VTGLRC+ C P YN F +C+ C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Query: 728 AGLAP---VDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTL 784
G P DP + C+C + +G C++C+PGF+ +SP N GC CSC G +
Sbjct: 905 LGTLPGTICDPISGQ----CLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAV 959
Query: 785 GGVAECQPGTGQCFCKP-HVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEP 843
+ C TGQC C+ + GQ C CKD +FG D C+ C C + GAL ++C
Sbjct: 960 NHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNETCHL 1016
Query: 844 RTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLE--LEEAATP-----------EGHAVR 890
TG C C+ G C D +P HL + L + TP A+
Sbjct: 1017 VTGQCFCKQFVTGSKC-----DACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAIN 1071
Query: 891 FGFNPLEFENFSWRGYA 907
++P + N W Y+
Sbjct: 1072 LSWSPPDSPNAHWLTYS 1088
Score = 212 bits (540), Expect = 5e-54
Identities = 136/454 (29%), Positives = 196/454 (43%), Gaps = 55/454 (12%)
Query: 468 FPSCYPTPSSSNDTREQVLPAGQI-VNCDCSAAGTQGNACRKDPRVGRCLCKPNF--QGT 524
F Y T ++ + R + +I ++ C G N C + RCLC +G
Sbjct: 489 FHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN-CDTTSQPYRCLCSQESFTEGL 547
Query: 525 HCELCAPGF-----------YGPGCQPCQCSSPGVA---DDRCDP--------DTGQCR- 561
HC+ C P + Y C+PCQC+S + + DP G C
Sbjct: 548 HCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD 607
Query: 562 CRVGFEGATCDRCAPGYFH--------FPLCQLCGCSPAGTLPEG--CDE-AGRCLCQPE 610
C G C+ C +F +C+ C C GT CD+ G+C C+
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667
Query: 611 FAGPHCDRCRPGYHGFPN-----CQACTCDPRGALDQ--LCGAG-GLCRCRPGYTGTACQ 662
+G C++C+ G++ C C C+ G +D C G C+C+ G C
Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 663 ECSPGFHGFPS-----CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF 717
C+ GF S C PC C+ GS++ C+P SGQC C+ GL+CDTC Y
Sbjct: 728 HCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL 787
Query: 718 PY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTR 775
C+A C AG P + C+C+ +VEG C++C G + L +N C
Sbjct: 788 DVTNCKACDCDTAGSLPGTVCNAKTG-QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLP 846
Query: 776 CSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGG 835
C+CD GT+ G C TGQC CK V G C C+ + L ++ C+ C CD G
Sbjct: 847 CNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906
Query: 836 AL-GQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
L G C+P +G C C PN QG C++ Y+
Sbjct: 907 TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Score = 187 bits (474), Expect = 2e-46
Identities = 121/377 (32%), Positives = 173/377 (45%), Gaps = 50/377 (13%)
Query: 1831 CLCPASY--RGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRC----------- 1873
CLC G C C P + +R ++ C PCQC+ HS C
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595
Query: 1874 ---LPGSGVCVDCQHNTEGAHCERCQAGFVSS-RDDPSAPCVSCPCPL-SVPSNNFAEGC 1928
G GVC DC+HNT G +CE C+ F DPSA V PC +V + N + C
Sbjct: 596 EHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILC 655
Query: 1929 VLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDC--SGNGDPNLLFSDCDP 1986
GG QC CK +G C +C GF+ + C PC+C SG D ++ C
Sbjct: 656 DQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDI---TCHQ 710
Query: 1987 LTGACRGCLRHTTGPRCEICAPGF-YGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCK 2043
+G C+ C + G RC+ C GF + + C C C G+ + C+PHSG C CK
Sbjct: 711 NSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK 769
Query: 2044 AGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE--GSECHPQSGQCHCRPGTMGPQCRE 2101
G +CD C+E +G D C+ C C A G+ C+ ++GQC C+P G QC +
Sbjct: 770 KEAKGLQCDTCRENFYGLD-VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828
Query: 2102 CAPGYWGLPEQG---CRRCQCP-------GGRCDPHTGRCNCPPGLSGERCDTCSQQHQV 2151
C G + L + C C C C+ TG+C C G++G RC+ C + H+
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQC-EPHRY 887
Query: 2152 PVPGGPVGHSIHCEVCD 2168
+ + + HC++C+
Sbjct: 888 NL---TIDNFQHCQMCE 901
Score = 174 bits (440), Expect = 2e-42
Identities = 111/324 (34%), Positives = 143/324 (44%), Gaps = 54/324 (16%)
Query: 1864 CQCHGHSDRCLPGSGV--CVDCQHN-TEGAHCERC-----QAGFVSSRDDPSAPCVSCPC 1915
CQCHGH+D C S C+ Q + TEG HC+RC F + C C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1916 PLSVPSNNFAEGCV------------LRGGRTQCL-CKPGYAGASCERCAPGFF----GN 1958
N+ ++ C RGG C C+ G +CE C FF +
Sbjct: 578 ------NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYG-NALLP 2017
P + C+PCDC G N CD + G C C RH +G +C C GFY L P
Sbjct: 632 PSAI-DVCKPCDCDTVGTRNGSIL-CDQIGGQCN-CKRHVSGRQCNQCQNGFYNLQELDP 688
Query: 2018 GNCTRCDCTPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG-----GCR 2068
C+ C+C GT C +SG C CKA V G RCD C +FGF GC
Sbjct: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCE 745
Query: 2069 PCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC------PG 2121
PC C ++ C+P SGQC C+ G QC C ++GL C+ C C PG
Sbjct: 746 PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPG 805
Query: 2122 GRCDPHTGRCNCPPGLSGERCDTC 2145
C+ TG+C C P + G +C+ C
Sbjct: 806 TVCNAKTGQCICKPNVEGRQCNKC 829
Score = 167 bits (422), Expect = 2e-40
Identities = 113/344 (32%), Positives = 151/344 (43%), Gaps = 41/344 (11%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCH--GHSD---RCLPGSGVCVDCQH 1885
C C G C +C GFY +++ L C PC C+ G D C SG C C+
Sbjct: 662 CNCKRHVSGRQCNQCQNGFY-NLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKA 719
Query: 1886 NTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAG 1945
N G C+ C GF R C C C L N F C G QC CK G
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKF---CNPHSG--QCECKKEAKG 774
Query: 1946 ASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C+ C F+G + ++C+ CDC G +L + C+ TG C C + G +C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAG--SLPGTVCNAKTGQCI-CKPNVEGRQCNK 828
Query: 2006 CAPG-FY---GNALLPGNCTRCDCTPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEG 2057
C G FY N+ L C C+C GT C+ +G C CK GVTG RC++C+
Sbjct: 829 CLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPH 885
Query: 2058 HFGF--DGCGGCRPCACGPAAE--GSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP--E 2111
+ D C+ C C G+ C P SGQC C P G +C +C PG++ P
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNA 945
Query: 2112 QGCRRCQC-----PGGRCDPHTGRCNC-PPGLSGERCDTCSQQH 2149
GC C C C+ TG+C C ++G+RCD C +
Sbjct: 946 TGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHY 989
Score = 165 bits (417), Expect = 9e-40
Identities = 112/335 (33%), Positives = 150/335 (44%), Gaps = 34/335 (10%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC--HGHSDR-CLPGSGVCVDCQHNT 1887
C C A+ G C C GF + ++ C PCQC HG ++ C P SG C +C+
Sbjct: 715 CKCKANVIGLRCDHCNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1888 EGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
+G C+ C+ F C +C C + G V QC+CKP G
Sbjct: 773 KGLQCDTCRENFYGL---DVTNCKACDCDTA----GSLPGTVCNAKTGQCICKPNVEGRQ 825
Query: 1948 CERCAPGFFGNPLVLGSSCQPCDCSGNGDPN--LLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C +C G F C PC+C G N LL C+ TG C C TG RC
Sbjct: 826 CNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQCP-CKLGVTGLRCNQ 881
Query: 2006 CAPGFYGNALLPG--NCTRCDCTPCGT---EACDPHSGHCLCKAGVTGRRCDRCQEGHFG 2060
C P Y N + +C C+C GT CDP SG CLC GRRC++CQ G +
Sbjct: 882 CEPHRY-NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Query: 2061 FDG-CGGCRPCACGPA-AEGSECHPQSGQCHCRPGTM-GPQCRECAPGYWGL-PEQG-CR 2115
G GC PC+C A C+ +GQC C+ ++ G +C +C Y+G P+ G C+
Sbjct: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000
Query: 2116 RCQCP-----GGRCDPHTGRCNCPPGLSGERCDTC 2145
C C C TG+C C ++G +CD C
Sbjct: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 159 bits (401), Expect = 6e-38
Identities = 99/289 (34%), Positives = 135/289 (46%), Gaps = 32/289 (11%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGS------GVCVDCQ 1884
C C +G C C FY GL + C C C LPG+ G C+ C+
Sbjct: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGS--LPGTVCNAKTGQCI-CK 818
Query: 1885 HNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRT-QCLCKPGY 1943
N EG C +C G R + S C+ C C + N G +L T QC CK G
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN----GSLLCNKSTGQCPCKLGV 874
Query: 1944 AGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC 2003
G C +C P + + CQ C+C G L + CDP++G C C+ + G RC
Sbjct: 875 TGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG--TLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTEA-----CDPHSGHCLCK-AGVTGRRCDRCQEG 2057
C PGFY + PGN T C C T C+ +G C+C+ A + G+RCD+C++
Sbjct: 932 NQCQPGFY---ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDH 988
Query: 2058 HFGFDG-CGGCRPCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAP 2104
+FGFD G C+PC C + +E CH +GQC C+ G +C C P
Sbjct: 989 YFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVP 1037
Score = 149 bits (377), Expect = 4e-35
Identities = 82/217 (37%), Positives = 106/217 (48%), Gaps = 28/217 (12%)
Query: 1436 RPCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWGFPN-----CRPCDC-- 1486
+PC C VG + C+ GGQC C HV GR C++C G++ C PC+C
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1487 -----GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPL-----VGCEECNCSGPGIQ 1536
G C + +GQC C I C C FG L VGCE C C+ G
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN---FGFKFLRSFNDVGCEPCQCNLHGS- 754
Query: 1537 ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPG-VCDPLT 1593
+ C+ SGQC+C+ G +CDTC F+G C+ CDC AG+ PG VC+ T
Sbjct: 755 --VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKT 812
Query: 1594 GQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
GQC CK NV+G +C++C G F L N C C C
Sbjct: 813 GQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 147 bits (372), Expect = 1e-34
Identities = 80/233 (34%), Positives = 102/233 (43%), Gaps = 30/233 (12%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF- 1478
C L F + G PC C+ G+ C P GQC C G C C ++G
Sbjct: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788
Query: 1479 -PNCRPCDCG------ARLCDELTGQCICPPRTIPPDCLLC--------QPQTFGCHPLV 1523
NC+ CDC +C+ TGQCIC P C C Q +F C P
Sbjct: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLP-- 846
Query: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSP-----GFHGYPRCRPCD 1578
CNC G C+ +GQC C+ VTG RC+ C P + C+ C+
Sbjct: 847 ----CNCDKTGTIN-GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCE 901
Query: 1579 CHEAGTAPG-VCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
C GT PG +CDP++GQC C N QG +C+QC G F + N GC C C
Sbjct: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSC 953
Score = 137 bits (344), Expect = 3e-31
Identities = 77/231 (33%), Positives = 107/231 (46%), Gaps = 24/231 (10%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGP--TCEPFGGQCPCHAHVIGRDCSRCATGY-- 1475
C+N +L +G PC C+ G TC GQC C A+VIG C C G+
Sbjct: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKF 735
Query: 1476 ---WGFPNCRPCDCGA-----RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527
+ C PC C + C+ +GQC C C C+ +G + C+
Sbjct: 736 LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCKA 794
Query: 1528 CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR------CRPCDCHE 1581
C+C G L C+ +GQC C+PNV GR+C+ C G + Y R C PC+C +
Sbjct: 795 CDCDTAG--SLPGTVCNAKTGQCICKPNVEGRQCNKCLEG-NFYLRQNNSFLCLPCNCDK 851
Query: 1582 AGTAPG--VCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
GT G +C+ TGQC CK V G +C+QC ++L N + C C C
Sbjct: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 136 bits (342), Expect = 4e-31
Identities = 72/211 (34%), Positives = 104/211 (49%), Gaps = 24/211 (11%)
Query: 1437 PCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWG-----FPNCRPCDCGA- 1488
PC C + G + C GQCPC V G C++C + F +C+ C+C +
Sbjct: 846 PCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSL 905
Query: 1489 -----RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHP--LVGCEECNCSGPGIQELTDP 1541
+CD ++GQC+C P C CQP F P GC C+C G +
Sbjct: 906 GTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGA---VNH 961
Query: 1542 TCDTDSGQCKCRP-NVTGRRCDTCSPGFHGYP----RCRPCDCHEAGTAPGVCDPLTGQC 1596
C++ +GQC C+ ++ G+RCD C + G+ RC+PC+CH +G C +TGQC
Sbjct: 962 ICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQC 1021
Query: 1597 YCKENVQGPKCDQCSLGTFSLDAANPKGCTR 1627
+CK+ V G KCD C LD N GC++
Sbjct: 1022 FCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052
Score = 130 bits (327), Expect = 2e-29
Identities = 76/229 (33%), Positives = 103/229 (44%), Gaps = 35/229 (15%)
Query: 1431 YNNGARPCGCHEVGAT---GPTCEPF--------GGQCP-CHAHVIGRDCSRCATGYW-- 1476
Y +PC C+ + + +PF GG C C + GR+C C ++
Sbjct: 568 YAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627
Query: 1477 ------GFPNCRPCDC-------GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLV 1523
C+PCDC G+ LCD++ GQC C C CQ + L
Sbjct: 628 VGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELD 687
Query: 1524 --GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRP 1576
GC CNC+ G + D TC +SGQCKC+ NV G RCD C+ GF C P
Sbjct: 688 PDGCSPCNCNTSGTVD-GDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEP 746
Query: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGC 1625
C C+ G+ C+P +GQC CK+ +G +CD C + LD N K C
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795
Score = 123 bits (309), Expect = 3e-27
Identities = 89/329 (27%), Positives = 129/329 (39%), Gaps = 62/329 (18%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGF---NQQPWKPATANSANEC 356
C C+ H +P QC C+ G CD C F + K ++A
Sbjct: 747 CQCNLHGSV---NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSL 803
Query: 357 QSCNCYGHATDCYYDPEVDRRRASQSLDG---------------------TYQGGGVC-- 393
C C P V+ R+ ++ L+G T G +C
Sbjct: 804 PGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK 863
Query: 394 ----IDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFT-DGT-CEDLTGRC 447
C+ TG+ C +C P Y N +D+ C+ C C+S T GT C+ ++G+C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRY---NLTIDNFQHCQMCECDSLGTLPGTICDPISGQC 920
Query: 448 YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACR 507
C PN G RC+ C GF Y +P ++ LP C C G + C
Sbjct: 921 LCVPNRQGRRCNQCQPGF------YISPGNATGC----LP------CSCHTTGAVNHICN 964
Query: 508 KDPRVGRCLCKP-NFQGTHCELCAPGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCR 561
G+C+C+ + G C+ C ++G CQPC C G ++ C TGQC
Sbjct: 965 S--LTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCF 1022
Query: 562 CRVGFEGATCDRCAPGYFHFPLCQLCGCS 590
C+ G+ CD C P H + L GCS
Sbjct: 1023 CKQFVTGSKCDACVPSASHLDVNNLLGCS 1051
Score = 115 bits (289), Expect = 6e-25
Identities = 76/247 (30%), Positives = 99/247 (40%), Gaps = 21/247 (8%)
Query: 1831 CLCPASYRGDSCQECAPG-FYRDVKGLFLGRCVPCQCH-----GHSDRCLPGSGVCVDCQ 1884
C+C + G C +C G FY FL C+PC C S C +G C C+
Sbjct: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFL--CLPCNCDKTGTINGSLLCNKSTGQC-PCK 871
Query: 1885 HNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYA 1944
G C +C+ + D C C C S G + QCLC P
Sbjct: 872 LGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD----SLGTLPGTICDPISGQCLCVPNRQ 927
Query: 1945 GASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCE 2004
G C +C PGF+ +P + C PC C G N + C+ LTG C G RC+
Sbjct: 928 GRRCNQCQPGFYISP-GNATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCD 983
Query: 2005 ICAPGFYGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRC--QEGHFG 2060
C ++G G C C+C G E C +G C CK VTG +CD C H
Sbjct: 984 QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLD 1043
Query: 2061 FDGCGGC 2067
+ GC
Sbjct: 1044 VNNLLGC 1050
Score = 83.2 bits (204), Expect = 4e-15
Identities = 59/218 (27%), Positives = 79/218 (36%), Gaps = 64/218 (29%)
Query: 1438 CGCH-EVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDC 1486
C CH T +P+ C + G C RC Y P NC+PC C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCE----ECNCSGPGIQELTDPT 1542
+ + CH + + E G G+
Sbjct: 578 NSH--------------------------SKSCHYNISVDPFPFEHFRGGGGV------- 604
Query: 1543 CDTDSGQCKCRPNVTGRRCDTCSPGFH--------GYPRCRPCDCHEAGTAPG--VCDPL 1592
CD C N TGR C+ C F C+PCDC GT G +CD +
Sbjct: 605 CDD------CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQI 658
Query: 1593 TGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
GQC CK +V G +C+QC G ++L +P GC+ C C
Sbjct: 659 GGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC 696
Score = 68.6 bits (166), Expect = 1e-10
Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 28/132 (21%)
Query: 1408 GYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCH-AHVIGR 1466
G++ISP +++ G PC CH GA C GQC C A + G+
Sbjct: 937 GFYISPGNAT----------------GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980
Query: 1467 DCSRCATGYWGFP----NCRPCDC---GA--RLCDELTGQCICPPRTIPPDCLLCQPQT- 1516
C +C Y+GF C+PC+C GA C +TGQC C C C P
Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSAS 1040
Query: 1517 -FGCHPLVGCEE 1527
+ L+GC +
Sbjct: 1041 HLDVNNLLGCSK 1052
Score = 37.0 bits (84), Expect = 0.36
Identities = 32/159 (20%), Positives = 64/159 (40%), Gaps = 18/159 (11%)
Query: 3545 LELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQ 3604
+ + R + GL+ + P +L +++ + R + + C+G+
Sbjct: 1740 ISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNGK 1799
Query: 3605 WHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAG-----APAPLYLGGLPEPMAVQ---- 3655
W+++ + K G+ + V+ H A+ +G +P+Y+GG+P+ +
Sbjct: 1800 WNKVIIKKEGSFISASVNGLMKH------ASESGDQPLVVNSPVYVGGIPQELLNSYQHL 1853
Query: 3656 PWPPAYCGCMRRLAVNRSPVAMTRSVEVHGA--VGASGC 3692
+ GCM+ + R V SV GA V GC
Sbjct: 1854 CLEQGFGGCMKDVKFTRGAVVNLASVS-SGAVRVNLDGC 1891
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 394 bits (1011), Expect = e-108
Identities = 247/756 (32%), Positives = 351/756 (46%), Gaps = 85/756 (11%)
Query: 113 KAHPASNAID---GTERWWQSPPLSRGLEYNE---VNVTLDLGQVFHVAYVLIKFANSPR 166
+AHP S D GT W S + + N+ ++V L+ GQ + V Y++I+F SP+
Sbjct: 338 EAHPLSFVNDNDVGTS--WVSNVFTNITQLNQGVTISVDLENGQ-YQVFYIIIQFF-SPQ 393
Query: 167 PDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLE 226
P ++R + ++ WQ+FA R+C FG + + + D+ C + S P
Sbjct: 394 PTEIRIQRKKENSLDWEDWQYFA---RNC-GAFGMKNNGDLEKPDSVNCL-QLSNFTPYS 448
Query: 227 NGEIVVSLV----NGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT 282
G + S++ N RPG NF +P L+EF KAT +R F H
Sbjct: 449 RGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHF--------HGQYYTTETAV 500
Query: 283 VTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQ 342
R YY++ +I+I GRC CHGHAD CD + P+R C+ + T G CDRC P +N
Sbjct: 501 NLRHRYYAVDEITISGRCQCHGHADNCDTT--SQPYRCLCSQESFTEGLHCDRCLPLYND 558
Query: 343 QPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTG 402
+P++ A C+ C C H+ C+Y+ VD + GGGVC DC+H+TTG
Sbjct: 559 KPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVD----PFPFEHFRGGGGVCDDCEHNTTG 614
Query: 403 VNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDG---TCEDLTGRCYCRPNFSGERCD 459
NCE C F+R + VC+ C+C++ T C+ + G+C C+ + SG +C+
Sbjct: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN 674
Query: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
C GF P S C+C+ +GT G+C CK
Sbjct: 675 QCQNGFYNLQELDPDGCSP---------------CNCNTSGTVDGDITCHQNSGQCKCKA 719
Query: 520 NFQGTHCELCAPG------FYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR 573
N G C+ C G F GC+PCQC+ G + C+P +GQC C+ +G CD
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779
Query: 574 CAPGYFHFPL--CQLCGCSPAGTLP-EGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPN- 628
C ++ + C+ C C AG+LP C+ + G+C+C+P G C++C G
Sbjct: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 629 ----CQACTCDPRGALD--QLCG-AGGLCRCRPGYTGTACQECSP-----GFHGFPSCVP 676
C C CD G ++ LC + G C C+ G TG C +C P F C
Sbjct: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899
Query: 677 CHCSAEGSLHAA-CDPRSGQCSCRPRVTGLRCDTCVPGAY----NFPYCEAGSCHPAGLA 731
C C + G+L CDP SGQC C P G RC+ C PG Y N C SCH G
Sbjct: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTG-- 957
Query: 732 PVDPALPEAQVPCMCR-AHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAEC 790
V+ C+C+ A + G CD+CK ++G P C C+C L G L C
Sbjct: 958 AVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSGALN--ETC 1014
Query: 791 QPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 826
TGQCFCK V G C +C LD + GC
Sbjct: 1015 HLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Score = 288 bits (737), Expect = 7e-77
Identities = 185/617 (29%), Positives = 270/617 (43%), Gaps = 114/617 (18%)
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C+GHA +C + R SQ + T G++C+RCLP + P
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQ---------------ESFTEGLHCDRCLPLYNDKPFR 562
Query: 419 PLDSPHV--CRRCNCESDFTD-------------------GTCEDLTGRCYCRPNFSGER 457
D + C+ C C S G C+D C N +G
Sbjct: 563 QGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD------CEHNTTGRN 616
Query: 458 CDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLC 517
C++C + F F PS+ + + CDC GT+ + D G+C C
Sbjct: 617 CELCKDYF--FRQVGADPSAIDVCKP----------CDCDTVGTRNGSILCDQIGGQCNC 664
Query: 518 KPNFQGTHCELCAPGFYG------PGCQPCQCSSPGVADD--RCDPDTGQCRCRVGFEGA 569
K + G C C GFY GC PC C++ G D C ++GQC+C+ G
Sbjct: 665 KRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGL 724
Query: 570 TCDRCAPGY-----FHFPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRPGY 623
CD C G+ F+ C+ C C+ G++ + C+ +G+C C+ E G CD CR +
Sbjct: 725 RCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENF 784
Query: 624 HGFP--NCQACTCDPRGALD-QLCGAG-GLCRCRPGYTGTACQECSPGFHGFPS-----C 674
+G NC+AC CD G+L +C A G C C+P G C +C G C
Sbjct: 785 YGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLC 844
Query: 675 VPCHCSAEGSLHAA--CDPRSGQCSCRPRVTGLRCDTCVPGAYN-----FPYCEAGSCHP 727
+PC+C G+++ + C+ +GQC C+ VTGLRC+ C P YN F +C+ C
Sbjct: 845 LPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDS 904
Query: 728 AGLAP---VDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTL 784
G P DP + C+C + +G C++C+PGF+ +SP N GC CSC G +
Sbjct: 905 LGTLPGTICDPISGQ----CLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAV 959
Query: 785 GGVAECQPGTGQCFCKP-HVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEP 843
+ C TGQC C+ + GQ C CKD +FG D C+ C C + GAL ++C
Sbjct: 960 NHI--CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTG-RCQPCNCHLSGALNETCHL 1016
Query: 844 RTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLE--LEEAATP-----------EGHAVR 890
TG C C+ G C D +P HL + L + TP A+
Sbjct: 1017 VTGQCFCKQFVTGSKC-----DACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAIN 1071
Query: 891 FGFNPLEFENFSWRGYA 907
++P + N W Y+
Sbjct: 1072 LSWSPPDSPNAHWLTYS 1088
Score = 212 bits (540), Expect = 5e-54
Identities = 136/454 (29%), Positives = 196/454 (43%), Gaps = 55/454 (12%)
Query: 468 FPSCYPTPSSSNDTREQVLPAGQI-VNCDCSAAGTQGNACRKDPRVGRCLCKPNF--QGT 524
F Y T ++ + R + +I ++ C G N C + RCLC +G
Sbjct: 489 FHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN-CDTTSQPYRCLCSQESFTEGL 547
Query: 525 HCELCAPGF-----------YGPGCQPCQCSSPGVA---DDRCDP--------DTGQCR- 561
HC+ C P + Y C+PCQC+S + + DP G C
Sbjct: 548 HCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDD 607
Query: 562 CRVGFEGATCDRCAPGYFH--------FPLCQLCGCSPAGTLPEG--CDE-AGRCLCQPE 610
C G C+ C +F +C+ C C GT CD+ G+C C+
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667
Query: 611 FAGPHCDRCRPGYHGFPN-----CQACTCDPRGALDQ--LCGAG-GLCRCRPGYTGTACQ 662
+G C++C+ G++ C C C+ G +D C G C+C+ G C
Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 663 ECSPGFHGFPS-----CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF 717
C+ GF S C PC C+ GS++ C+P SGQC C+ GL+CDTC Y
Sbjct: 728 HCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL 787
Query: 718 PY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTR 775
C+A C AG P + C+C+ +VEG C++C G + L +N C
Sbjct: 788 DVTNCKACDCDTAGSLPGTVCNAKTG-QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLP 846
Query: 776 CSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGG 835
C+CD GT+ G C TGQC CK V G C C+ + L ++ C+ C CD G
Sbjct: 847 CNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906
Query: 836 AL-GQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
L G C+P +G C C PN QG C++ Y+
Sbjct: 907 TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Score = 187 bits (474), Expect = 2e-46
Identities = 121/377 (32%), Positives = 173/377 (45%), Gaps = 50/377 (13%)
Query: 1831 CLCPASY--RGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRC----------- 1873
CLC G C C P + +R ++ C PCQC+ HS C
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595
Query: 1874 ---LPGSGVCVDCQHNTEGAHCERCQAGFVSS-RDDPSAPCVSCPCPL-SVPSNNFAEGC 1928
G GVC DC+HNT G +CE C+ F DPSA V PC +V + N + C
Sbjct: 596 EHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILC 655
Query: 1929 VLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDC--SGNGDPNLLFSDCDP 1986
GG QC CK +G C +C GF+ + C PC+C SG D ++ C
Sbjct: 656 DQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDI---TCHQ 710
Query: 1987 LTGACRGCLRHTTGPRCEICAPGF-YGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCK 2043
+G C+ C + G RC+ C GF + + C C C G+ + C+PHSG C CK
Sbjct: 711 NSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECK 769
Query: 2044 AGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE--GSECHPQSGQCHCRPGTMGPQCRE 2101
G +CD C+E +G D C+ C C A G+ C+ ++GQC C+P G QC +
Sbjct: 770 KEAKGLQCDTCRENFYGLD-VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828
Query: 2102 CAPGYWGLPEQG---CRRCQCP-------GGRCDPHTGRCNCPPGLSGERCDTCSQQHQV 2151
C G + L + C C C C+ TG+C C G++G RC+ C + H+
Sbjct: 829 CLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQC-EPHRY 887
Query: 2152 PVPGGPVGHSIHCEVCD 2168
+ + + HC++C+
Sbjct: 888 NL---TIDNFQHCQMCE 901
Score = 174 bits (440), Expect = 2e-42
Identities = 111/324 (34%), Positives = 143/324 (44%), Gaps = 54/324 (16%)
Query: 1864 CQCHGHSDRCLPGSGV--CVDCQHN-TEGAHCERC-----QAGFVSSRDDPSAPCVSCPC 1915
CQCHGH+D C S C+ Q + TEG HC+RC F + C C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1916 PLSVPSNNFAEGCV------------LRGGRTQCL-CKPGYAGASCERCAPGFF----GN 1958
N+ ++ C RGG C C+ G +CE C FF +
Sbjct: 578 ------NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYG-NALLP 2017
P + C+PCDC G N CD + G C C RH +G +C C GFY L P
Sbjct: 632 PSAI-DVCKPCDCDTVGTRNGSIL-CDQIGGQCN-CKRHVSGRQCNQCQNGFYNLQELDP 688
Query: 2018 GNCTRCDCTPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG-----GCR 2068
C+ C+C GT C +SG C CKA V G RCD C +FGF GC
Sbjct: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC---NFGFKFLRSFNDVGCE 745
Query: 2069 PCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC------PG 2121
PC C ++ C+P SGQC C+ G QC C ++GL C+ C C PG
Sbjct: 746 PCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPG 805
Query: 2122 GRCDPHTGRCNCPPGLSGERCDTC 2145
C+ TG+C C P + G +C+ C
Sbjct: 806 TVCNAKTGQCICKPNVEGRQCNKC 829
Score = 167 bits (422), Expect = 2e-40
Identities = 113/344 (32%), Positives = 151/344 (43%), Gaps = 41/344 (11%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCH--GHSD---RCLPGSGVCVDCQH 1885
C C G C +C GFY +++ L C PC C+ G D C SG C C+
Sbjct: 662 CNCKRHVSGRQCNQCQNGFY-NLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKA 719
Query: 1886 NTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAG 1945
N G C+ C GF R C C C L N F C G QC CK G
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKF---CNPHSG--QCECKKEAKG 774
Query: 1946 ASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C+ C F+G + ++C+ CDC G +L + C+ TG C C + G +C
Sbjct: 775 LQCDTCRENFYGLDV---TNCKACDCDTAG--SLPGTVCNAKTGQCI-CKPNVEGRQCNK 828
Query: 2006 CAPG-FY---GNALLPGNCTRCDCTPCGTE----ACDPHSGHCLCKAGVTGRRCDRCQEG 2057
C G FY N+ L C C+C GT C+ +G C CK GVTG RC++C+
Sbjct: 829 CLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPH 885
Query: 2058 HFGF--DGCGGCRPCACGPAAE--GSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP--E 2111
+ D C+ C C G+ C P SGQC C P G +C +C PG++ P
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNA 945
Query: 2112 QGCRRCQC-----PGGRCDPHTGRCNC-PPGLSGERCDTCSQQH 2149
GC C C C+ TG+C C ++G+RCD C +
Sbjct: 946 TGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHY 989
Score = 165 bits (417), Expect = 9e-40
Identities = 112/335 (33%), Positives = 150/335 (44%), Gaps = 34/335 (10%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC--HGHSDR-CLPGSGVCVDCQHNT 1887
C C A+ G C C GF + ++ C PCQC HG ++ C P SG C +C+
Sbjct: 715 CKCKANVIGLRCDHCNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEA 772
Query: 1888 EGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
+G C+ C+ F C +C C + G V QC+CKP G
Sbjct: 773 KGLQCDTCRENFYGL---DVTNCKACDCDTA----GSLPGTVCNAKTGQCICKPNVEGRQ 825
Query: 1948 CERCAPGFFGNPLVLGSSCQPCDCSGNGDPN--LLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C +C G F C PC+C G N LL C+ TG C C TG RC
Sbjct: 826 CNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQCP-CKLGVTGLRCNQ 881
Query: 2006 CAPGFYGNALLPG--NCTRCDCTPCGT---EACDPHSGHCLCKAGVTGRRCDRCQEGHFG 2060
C P Y N + +C C+C GT CDP SG CLC GRRC++CQ G +
Sbjct: 882 CEPHRY-NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Query: 2061 FDG-CGGCRPCACGPA-AEGSECHPQSGQCHCRPGTM-GPQCRECAPGYWGL-PEQG-CR 2115
G GC PC+C A C+ +GQC C+ ++ G +C +C Y+G P+ G C+
Sbjct: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000
Query: 2116 RCQCP-----GGRCDPHTGRCNCPPGLSGERCDTC 2145
C C C TG+C C ++G +CD C
Sbjct: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 159 bits (401), Expect = 6e-38
Identities = 99/289 (34%), Positives = 135/289 (46%), Gaps = 32/289 (11%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGS------GVCVDCQ 1884
C C +G C C FY GL + C C C LPG+ G C+ C+
Sbjct: 766 CECKKEAKGLQCDTCRENFY----GLDVTNCKACDCDTAGS--LPGTVCNAKTGQCI-CK 818
Query: 1885 HNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRT-QCLCKPGY 1943
N EG C +C G R + S C+ C C + N G +L T QC CK G
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN----GSLLCNKSTGQCPCKLGV 874
Query: 1944 AGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC 2003
G C +C P + + CQ C+C G L + CDP++G C C+ + G RC
Sbjct: 875 TGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG--TLPGTICDPISGQCL-CVPNRQGRRC 931
Query: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTEA-----CDPHSGHCLCK-AGVTGRRCDRCQEG 2057
C PGFY + PGN T C C T C+ +G C+C+ A + G+RCD+C++
Sbjct: 932 NQCQPGFY---ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDH 988
Query: 2058 HFGFDG-CGGCRPCACGPAAEGSE-CHPQSGQCHCRPGTMGPQCRECAP 2104
+FGFD G C+PC C + +E CH +GQC C+ G +C C P
Sbjct: 989 YFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVP 1037
Score = 149 bits (377), Expect = 4e-35
Identities = 82/217 (37%), Positives = 106/217 (48%), Gaps = 28/217 (12%)
Query: 1436 RPCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWGFPN-----CRPCDC-- 1486
+PC C VG + C+ GGQC C HV GR C++C G++ C PC+C
Sbjct: 639 KPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 1487 -----GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPL-----VGCEECNCSGPGIQ 1536
G C + +GQC C I C C FG L VGCE C C+ G
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCN---FGFKFLRSFNDVGCEPCQCNLHGS- 754
Query: 1537 ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPG-VCDPLT 1593
+ C+ SGQC+C+ G +CDTC F+G C+ CDC AG+ PG VC+ T
Sbjct: 755 --VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKT 812
Query: 1594 GQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
GQC CK NV+G +C++C G F L N C C C
Sbjct: 813 GQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 147 bits (372), Expect = 1e-34
Identities = 80/233 (34%), Positives = 102/233 (43%), Gaps = 30/233 (12%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF- 1478
C L F + G PC C+ G+ C P GQC C G C C ++G
Sbjct: 729 CNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLD 788
Query: 1479 -PNCRPCDCG------ARLCDELTGQCICPPRTIPPDCLLC--------QPQTFGCHPLV 1523
NC+ CDC +C+ TGQCIC P C C Q +F C P
Sbjct: 789 VTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLP-- 846
Query: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSP-----GFHGYPRCRPCD 1578
CNC G C+ +GQC C+ VTG RC+ C P + C+ C+
Sbjct: 847 ----CNCDKTGTIN-GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCE 901
Query: 1579 CHEAGTAPG-VCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
C GT PG +CDP++GQC C N QG +C+QC G F + N GC C C
Sbjct: 902 CDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSC 953
Score = 137 bits (344), Expect = 3e-31
Identities = 77/231 (33%), Positives = 107/231 (46%), Gaps = 24/231 (10%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGP--TCEPFGGQCPCHAHVIGRDCSRCATGY-- 1475
C+N +L +G PC C+ G TC GQC C A+VIG C C G+
Sbjct: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKF 735
Query: 1476 ---WGFPNCRPCDCGA-----RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527
+ C PC C + C+ +GQC C C C+ +G + C+
Sbjct: 736 LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCKA 794
Query: 1528 CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR------CRPCDCHE 1581
C+C G L C+ +GQC C+PNV GR+C+ C G + Y R C PC+C +
Sbjct: 795 CDCDTAG--SLPGTVCNAKTGQCICKPNVEGRQCNKCLEG-NFYLRQNNSFLCLPCNCDK 851
Query: 1582 AGTAPG--VCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
GT G +C+ TGQC CK V G +C+QC ++L N + C C C
Sbjct: 852 TGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 136 bits (342), Expect = 4e-31
Identities = 72/211 (34%), Positives = 104/211 (49%), Gaps = 24/211 (11%)
Query: 1437 PCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWG-----FPNCRPCDCGA- 1488
PC C + G + C GQCPC V G C++C + F +C+ C+C +
Sbjct: 846 PCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSL 905
Query: 1489 -----RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHP--LVGCEECNCSGPGIQELTDP 1541
+CD ++GQC+C P C CQP F P GC C+C G +
Sbjct: 906 GTLPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCHTTGA---VNH 961
Query: 1542 TCDTDSGQCKCRP-NVTGRRCDTCSPGFHGYP----RCRPCDCHEAGTAPGVCDPLTGQC 1596
C++ +GQC C+ ++ G+RCD C + G+ RC+PC+CH +G C +TGQC
Sbjct: 962 ICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQC 1021
Query: 1597 YCKENVQGPKCDQCSLGTFSLDAANPKGCTR 1627
+CK+ V G KCD C LD N GC++
Sbjct: 1022 FCKQFVTGSKCDACVPSASHLDVNNLLGCSK 1052
Score = 130 bits (327), Expect = 2e-29
Identities = 76/229 (33%), Positives = 103/229 (44%), Gaps = 35/229 (15%)
Query: 1431 YNNGARPCGCHEVGAT---GPTCEPF--------GGQCP-CHAHVIGRDCSRCATGYW-- 1476
Y +PC C+ + + +PF GG C C + GR+C C ++
Sbjct: 568 YAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627
Query: 1477 ------GFPNCRPCDC-------GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLV 1523
C+PCDC G+ LCD++ GQC C C CQ + L
Sbjct: 628 VGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELD 687
Query: 1524 --GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRP 1576
GC CNC+ G + D TC +SGQCKC+ NV G RCD C+ GF C P
Sbjct: 688 PDGCSPCNCNTSGTVD-GDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEP 746
Query: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGC 1625
C C+ G+ C+P +GQC CK+ +G +CD C + LD N K C
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795
Score = 123 bits (309), Expect = 3e-27
Identities = 89/329 (27%), Positives = 129/329 (39%), Gaps = 62/329 (18%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGF---NQQPWKPATANSANEC 356
C C+ H +P QC C+ G CD C F + K ++A
Sbjct: 747 CQCNLHGSV---NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSL 803
Query: 357 QSCNCYGHATDCYYDPEVDRRRASQSLDG---------------------TYQGGGVC-- 393
C C P V+ R+ ++ L+G T G +C
Sbjct: 804 PGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNK 863
Query: 394 ----IDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFT-DGT-CEDLTGRC 447
C+ TG+ C +C P Y N +D+ C+ C C+S T GT C+ ++G+C
Sbjct: 864 STGQCPCKLGVTGLRCNQCEPHRY---NLTIDNFQHCQMCECDSLGTLPGTICDPISGQC 920
Query: 448 YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACR 507
C PN G RC+ C GF Y +P ++ LP C C G + C
Sbjct: 921 LCVPNRQGRRCNQCQPGF------YISPGNATGC----LP------CSCHTTGAVNHICN 964
Query: 508 KDPRVGRCLCKP-NFQGTHCELCAPGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCR 561
G+C+C+ + G C+ C ++G CQPC C G ++ C TGQC
Sbjct: 965 S--LTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCF 1022
Query: 562 CRVGFEGATCDRCAPGYFHFPLCQLCGCS 590
C+ G+ CD C P H + L GCS
Sbjct: 1023 CKQFVTGSKCDACVPSASHLDVNNLLGCS 1051
Score = 115 bits (289), Expect = 6e-25
Identities = 76/247 (30%), Positives = 99/247 (40%), Gaps = 21/247 (8%)
Query: 1831 CLCPASYRGDSCQECAPG-FYRDVKGLFLGRCVPCQCH-----GHSDRCLPGSGVCVDCQ 1884
C+C + G C +C G FY FL C+PC C S C +G C C+
Sbjct: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFL--CLPCNCDKTGTINGSLLCNKSTGQC-PCK 871
Query: 1885 HNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYA 1944
G C +C+ + D C C C S G + QCLC P
Sbjct: 872 LGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD----SLGTLPGTICDPISGQCLCVPNRQ 927
Query: 1945 GASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCE 2004
G C +C PGF+ +P + C PC C G N + C+ LTG C G RC+
Sbjct: 928 GRRCNQCQPGFYISP-GNATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCD 983
Query: 2005 ICAPGFYGNALLPGNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRC--QEGHFG 2060
C ++G G C C+C G E C +G C CK VTG +CD C H
Sbjct: 984 QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLD 1043
Query: 2061 FDGCGGC 2067
+ GC
Sbjct: 1044 VNNLLGC 1050
Score = 83.2 bits (204), Expect = 4e-15
Identities = 59/218 (27%), Positives = 79/218 (36%), Gaps = 64/218 (29%)
Query: 1438 CGCH-EVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDC 1486
C CH T +P+ C + G C RC Y P NC+PC C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCE----ECNCSGPGIQELTDPT 1542
+ + CH + + E G G+
Sbjct: 578 NSH--------------------------SKSCHYNISVDPFPFEHFRGGGGV------- 604
Query: 1543 CDTDSGQCKCRPNVTGRRCDTCSPGFH--------GYPRCRPCDCHEAGTAPG--VCDPL 1592
CD C N TGR C+ C F C+PCDC GT G +CD +
Sbjct: 605 CDD------CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQI 658
Query: 1593 TGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
GQC CK +V G +C+QC G ++L +P GC+ C C
Sbjct: 659 GGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC 696
Score = 68.6 bits (166), Expect = 1e-10
Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 28/132 (21%)
Query: 1408 GYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCH-AHVIGR 1466
G++ISP +++ G PC CH GA C GQC C A + G+
Sbjct: 937 GFYISPGNAT----------------GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980
Query: 1467 DCSRCATGYWGFP----NCRPCDC---GA--RLCDELTGQCICPPRTIPPDCLLCQPQT- 1516
C +C Y+GF C+PC+C GA C +TGQC C C C P
Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSAS 1040
Query: 1517 -FGCHPLVGCEE 1527
+ L+GC +
Sbjct: 1041 HLDVNNLLGCSK 1052
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 385 bits (988), Expect = e-106
Identities = 406/1480 (27%), Positives = 572/1480 (38%), Gaps = 282/1480 (19%)
Query: 1431 YNNGARPCGCH--------EVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWGFPN- 1480
+++ R C CH ++ + GG C C + GR C C ++ P
Sbjct: 340 HSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK 399
Query: 1481 -------CRPCDC-------GARLCDE--------LTGQCICPPRTIPPDCLLCQPQTFG 1518
CR CDC G R CD ++GQC C + C C+ FG
Sbjct: 400 DLRDPAVCRSCDCDPMGSQDGGR-CDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
Query: 1519 CH--PLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR--- 1573
+GC C C+ G + P CD +SG C C+ VTGR CD C PG G
Sbjct: 459 LSISDRLGCRRCQCNARGTVPGSTP-CDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLL 517
Query: 1574 -CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
CRPCDC G CD TGQC+C++++ G +C+Q G F R F
Sbjct: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF-----------RPFL-- 564
Query: 1633 ATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQ--PGTEMLRAD----LRHVPEAVP 1686
+ E D G VL +R V P E G+ +R L + +VP
Sbjct: 565 --------DHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVP 616
Query: 1687 EAFP-----ELYWQAPPSY--LGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQG 1739
+A L Q P + L V G + L VP + R LQ
Sbjct: 617 KAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGH------LVPKDDRIQGTLQP 670
Query: 1740 NQMSITFLEPAYPTPGHVHRGQLQLVE-GNFRHTETRNTVSREELMMVLASLEQLQIRAL 1798
+ + F P PG ++ L+LV G ET + L+ L L ++ + +
Sbjct: 671 HARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYS-GPGLLIDSLVLLPRVLVLEM 729
Query: 1799 FSQISSAVFLRRVALE------------VASPA------------------------GQG 1822
FS +A R+ E SP+ QG
Sbjct: 730 FSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQG 789
Query: 1823 ALASNVE----LCLCPASYRGDSCQECAPGFY----------------------RDVKGL 1856
+L+S CLC G C CAPG+Y G
Sbjct: 790 SLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQ 849
Query: 1857 FLGR--------------------CVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQ 1896
L R C PC C+GH+D C +G C+ C+ +T G HCERC
Sbjct: 850 CLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCI 909
Query: 1897 AGFVSSRDDPSAP----CVSCPCPLSVPS-NNFAEGCVLRGGRTQ--CLCKPGYAGASCE 1949
AGF DP P C CPCP S +FA C Q C C+ GY G CE
Sbjct: 910 AGF---HGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCE 966
Query: 1950 RCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPG 2009
CAPG FG+P G CQ C+CSGN DP + CDP TG C CL HT GP C C PG
Sbjct: 967 ACAPGHFGDPSRPGGRCQLCECSGNIDP-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025
Query: 2010 FYGNALLPGNCTRCDCTPCGTEA----------CDPHSGHCLCKAGVTGRRCDRCQEGHF 2059
F+G A +C RC C GT CDP SG C C V G CDRC +
Sbjct: 1026 FHGQAARQ-SCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
Query: 2060 GFDGCGGCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQ 2118
GC+PCAC P+ A G C+ +GQCHCR G G C EC +WG P C C
Sbjct: 1085 NLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACD 1144
Query: 2119 CPG-----GRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVL 2173
C +C TG C+C PG+SG RCD C++ P C C C
Sbjct: 1145 CDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPA--------CHPCHAC--- 1193
Query: 2174 LLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQL---RSPLGPRH--- 2227
D +R L A ++L L +S +Q +L + +G R+
Sbjct: 1194 -FGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSA 1252
Query: 2228 -ETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLA---AIR 2283
TAQ +E E+ +G+ L D + A G + LA +R
Sbjct: 1253 ASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLR 1312
Query: 2284 AVDRTLSELMSQTGHLG----LANASAPSGEQLLR----TLAEVERLLWEMRARD----- 2330
+D+ L +L+ + LG + +A + S E R LA + AR
Sbjct: 1313 QLDQHL-DLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEAL 1371
Query: 2331 LGAPQAAAEAELAAAQRLLARVQEQLS--SLWEENQAL---------------ATQTRDR 2373
+ A + ++ A QR L ++ SL + N+ + RD
Sbjct: 1372 MDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDE 1431
Query: 2374 LAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEA---LQRKQELSRDNATLQATL 2430
Q G + A A A A+ + Q L E L R E R + Q
Sbjct: 1432 DGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRA 1491
Query: 2431 HAARDTLASVFRLLHSLDQAKEELERLAASL------DGARTPLLQRMQTFSPAGSKLRL 2484
AA D A+ R ++QA +EL+ L S+ +GA ++ + T R+
Sbjct: 1492 QAALDK-ANASR--GQVEQANQELQELIQSVKDFLNQEGADPDSIEMVAT--------RV 1540
Query: 2485 VE-AAEAHAQQLGQLALNLSSIILDV-NQDRLTQRAIEASNAYSRILQAVQAAEDAAGQA 2542
+E + A A+Q+ LA ++ + + + D + R + ++LQ + A A
Sbjct: 1541 LELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDE 1600
Query: 2543 LQQADHTWATVVR----QGLVDRA-QQLLANSTALEEAMLQEQQRLGLVWAALQGARTQL 2597
Q+A+ A + QG+ A + +A++ E+ + Q Q+R+ AL A +
Sbjct: 1601 KQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERA 1660
Query: 2598 RDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAE------AQDTATRVQSQLQ 2651
R + A + L+ ++ A LA T E + A +A AE D V++ +
Sbjct: 1661 RQLDALLEALK--LKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAE 1718
Query: 2652 AMQENVERWQGQYEGLR--GQDLGQAVLDAGHSVSTLEKT 2689
+ V Q + E LR +DL QA D + LE T
Sbjct: 1719 RKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGT 1758
Score = 271 bits (692), Expect = 1e-71
Identities = 185/595 (31%), Positives = 267/595 (44%), Gaps = 94/595 (15%)
Query: 22 LLLVGLALLGAARAREEAG-GGFSLHPPYFNLAEGA--RIAASATCGEEAPARGSPRPTE 78
LL V A L A A + G S +P +L G R+ AS+TCG P+P
Sbjct: 23 LLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCG-----LNGPQP-- 75
Query: 79 DLYCKLVGGPVAGGDPNQTIRGQYCDIC------TAANSNKAHPASNAIDG-----TERW 127
YC + + + C +C +A ++ +H N + W
Sbjct: 76 --YCIV----------SHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAW 123
Query: 128 WQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
WQS G+ V + LDL FH ++++ F RP ++ERS DFGRT+ +++
Sbjct: 124 WQS---ENGIP--AVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLVERSADFGRTWHVYRY 177
Query: 188 FASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYS 247
F+ DC F L D +C + YS I P GE++ +++ + YS
Sbjct: 178 FSY---DCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPD-PYS 233
Query: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT--VTRRYYYSIKDISIGGRCVCHGH 305
++ K TN+R+ R +TL G L DP + +YYY++ ++ + G C C+GH
Sbjct: 234 SRIQNLLKITNLRVNLTRLHTL-----GDNLLDPRREIREKYYYALYELVVRGNCFCYGH 288
Query: 306 ADACDAKDPTDPFRLQ------CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
A C A P P + C C+HNT G C++C + PW+PA ++ C+ C
Sbjct: 289 ASEC-APAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKC 347
Query: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
C+GH C++D V + S GGVC CQH+T G +CE C P FYR P
Sbjct: 348 ECHGHTHSCHFDMAVYLASGNVS-------GGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 420 LDSPHVCRRCNCE--SDFTDGTCED--------LTGRCYCRPNFSGERCDVCAEGFTGFP 469
L P VCR C+C+ G C+ ++G+C C+ + G RC C +GF G
Sbjct: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL- 459
Query: 470 SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
+ S R C C+A GT + DP G C CK G C+ C
Sbjct: 460 ----SISDRLGCR----------RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRC 505
Query: 530 APGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYF 579
PG +G GC+PC C G D +CD TGQC CR G C++ PGYF
Sbjct: 506 LPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 259 bits (661), Expect = 4e-68
Identities = 150/410 (36%), Positives = 190/410 (46%), Gaps = 53/410 (12%)
Query: 494 CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGVAD 550
C C+ G+ + C +P G+CLCKP G C+LCAPG+YG GCQ CQCS G
Sbjct: 783 CQCNPQGSLSSEC--NPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS 840
Query: 551 DRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCL-CQP 609
C+ +GQC CR G G CDRC G + FP C+ C C+ G E G CL C+
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHADECNTHTGACLGCRD 898
Query: 610 EFAGPHCDRCRPGYHGFP------NCQACTCDPRGALDQLCGAGG----------LCRCR 653
G HC+RC G+HG P C+ C C P G Q A +C CR
Sbjct: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYSQQIVCHCR 957
Query: 654 PGYTGTACQECSPGFHGFPS-----CVPCHCSAEGSLHA----ACDPRSGQC-SCRPRVT 703
GYTG C+ C+PG G PS C C CS G++ ACDP +GQC C
Sbjct: 958 AGYTGLRCEACAPGHFGDPSRPGGRCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTE 1015
Query: 704 GLRCDTCVPGAYN---FPYCEAGSCHPAGLAPVDPALPE------AQVPCMCRAHVEGPS 754
G C C PG + C +C+ G P P+ + C C +V+GPS
Sbjct: 1016 GPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPS 1075
Query: 755 CDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDG 814
CDRC P FW L+ + GC C+C G C TGQC C+ G+ C+ C++
Sbjct: 1076 CDRCAPNFWNLTSGH--GCQPCACHPSRARG--PTCNEFTGQCHCRAGFGGRTCSECQEL 1131
Query: 815 FFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPAR 864
+G C +C CD G C TG C CRP G C + AR
Sbjct: 1132 HWG---DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCAR 1178
Score = 238 bits (608), Expect = 6e-62
Identities = 138/361 (38%), Positives = 173/361 (47%), Gaps = 36/361 (9%)
Query: 537 GCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF--PLCQLCGCSPAGT 594
G PCQC+ G C+P GQC C+ G G CD CAPGY+ F CQ C CS G
Sbjct: 779 GALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGA 838
Query: 595 LPEGCDE-AGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC-RC 652
L C++ +G+CLC+ G CDRC+ G GFP+C+ C C+ G D+ G C C
Sbjct: 839 LSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHADECNTHTGACLGC 896
Query: 653 RPGYTGTACQECSPGFHGFP------SCVPCHC----SAEGSLHAAC--DPRSGQ--CSC 698
R G C+ C GFHG P C PC C ++ +C D S Q C C
Sbjct: 897 RDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHC 956
Query: 699 RPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLA-PVDPALPEAQVP----CM-CRAHVEG 752
R TGLRC+ C PG + P G C + +DP P+A P C+ C H EG
Sbjct: 957 RAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
Query: 753 PSCDRCKPGFWGLSPSNPEGCTRCSCDLRGT------LGGVAECQPGTGQCFCKPHVCGQ 806
P C CKPGF G + + C RC+C+L GT C P +GQC C P+V G
Sbjct: 1017 PHCAHCKPGFHGQAAR--QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
Query: 807 ACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
+C C F+ L GC+ C C A G +C TG C CR G TCSE H
Sbjct: 1075 SCDRCAPNFWNLTSG--HGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELH 1132
Query: 867 Y 867
+
Sbjct: 1133 W 1133
Score = 206 bits (524), Expect = 3e-52
Identities = 148/448 (33%), Positives = 182/448 (40%), Gaps = 89/448 (19%)
Query: 316 DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVD 375
+P QC C+ G CD C PG+ CQ+C C
Sbjct: 796 NPHGGQCLCKPGVVGRRCDLCAPGYY--------GFGPTGCQACQC-------------S 834
Query: 376 RRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDF 435
A SL + G C+ C+ G+ C+RC G + P+ CR C C
Sbjct: 835 HEGALSSL--CEKTSGQCL-CRTGAFGLRCDRCQRGQWGFPS--------CRPCVCNGHA 883
Query: 436 TDGTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP-AGQIVN 493
+ C TG C CR + GE C+ C GF G P LP GQ
Sbjct: 884 DE--CNTHTGACLGCRDHTGGEHCERCIAGFHGDPR---------------LPYGGQCRP 926
Query: 494 CDC-SAAGTQ---GNACRKDPRVGR--CLCKPNFQGTHCELCAPGFYG----PG--CQPC 541
C C G+Q +C +D + C C+ + G CE CAPG +G PG CQ C
Sbjct: 927 CPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLC 986
Query: 542 QCSS--PGVADDRCDPDTGQC-RCRVGFEGATCDRCAPGYFHFPL----CQLCGCSPAGT 594
+CS + D CDP TGQC RC EG C C PG FH C C C+ GT
Sbjct: 987 ECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG-FHGQAARQSCHRCTCNLLGT 1045
Query: 595 LPEGCDE---------AGRCLCQPEFAGPHCDRCRPGYHGFPN---CQACTCDPRGALDQ 642
P+ C +G+C C P GP CDRC P + + CQ C C P A
Sbjct: 1046 NPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGP 1105
Query: 643 LCGA-GGLCRCRPGYTGTACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQCSCR 699
C G C CR G+ G C EC G P C C C + G C +G CSCR
Sbjct: 1106 TCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCR 1165
Query: 700 PRVTGLRCDTCVPGAYN-FPYCEAGSCH 726
P V+G+RCD C G FP C CH
Sbjct: 1166 PGVSGVRCDQCARGFSGIFPACH--PCH 1191
Score = 187 bits (476), Expect = 1e-46
Identities = 129/408 (31%), Positives = 165/408 (40%), Gaps = 72/408 (17%)
Query: 428 RCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGF--PSCYPTPSSSNDTREQV 485
+CN + + C G+C C+P G RCD+CA G+ GF C S +
Sbjct: 784 QCNPQGSLSS-ECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSL 842
Query: 486 L--PAGQI--------VNCD-----------CSAAGTQGNACRKDPRVGRCL-CKPNFQG 523
+GQ + CD C G+A + G CL C+ + G
Sbjct: 843 CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGG 902
Query: 524 THCELCAPGF-------YGPGCQPCQC-SSPGVA---DDRCDPDTGQ----CRCRVGFEG 568
HCE C GF YG C+PC C PG C D C CR G+ G
Sbjct: 903 EHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTG 962
Query: 569 ATCDRCAPGYFHFP-----LCQLCGCSPAGTL----PEGCD-EAGRCL-CQPEFAGPHCD 617
C+ CAPG+F P CQLC CS G + P+ CD G+CL C GPHC
Sbjct: 963 LRCEACAPGHFGDPSRPGGRCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCA 1020
Query: 618 RCRPGYHG---FPNCQACTCDPRGALDQLC---------GAGGLCRCRPGYTGTACQECS 665
C+PG+HG +C CTC+ G Q C + G C C P G +C C+
Sbjct: 1021 HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA 1080
Query: 666 PGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFP--YC 720
P F S C PC C + C+ +GQC CR G C C + P C
Sbjct: 1081 PNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC 1140
Query: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768
A C G+ P C CR V G CD+C GF G+ P+
Sbjct: 1141 HACDCDSRGID--TPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPA 1186
Score = 175 bits (443), Expect = 9e-43
Identities = 113/355 (31%), Positives = 144/355 (40%), Gaps = 63/355 (17%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
CVC+GHAD C+ C C+ +T G C+RC GF+ P P +C+
Sbjct: 877 CVCNGHADECNTHTGA------CLGCRDHTGGEHCERCIAGFHGDPRLP----YGGQCRP 926
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C P R A+ Y VC C+ TG+ CE C PG + P+
Sbjct: 927 C-------PCPEGPGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDPSR 978
Query: 419 PLDSPHVCRRCNCESD---FTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFTG---FPSC 471
P C+ C C + C+ TG+C C + G C C GF G SC
Sbjct: 979 PGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSC 1035
Query: 472 YPTPSSSNDTREQVLPAGQIVNCDCSAAGT------QGNACRKDPRVGRCLCKPNFQGTH 525
+ C C+ GT + C DP G+C C PN QG
Sbjct: 1036 H--------------------RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPS 1075
Query: 526 CELCAPGFY----GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF 581
C+ CAP F+ G GCQPC C C+ TGQC CR GF G TC C ++
Sbjct: 1076 CDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGD 1135
Query: 582 P--LCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYHG-FPNCQAC 632
P C C C G C G C C+P +G CD+C G+ G FP C C
Sbjct: 1136 PGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPC 1190
Score = 164 bits (415), Expect = 2e-39
Identities = 102/280 (36%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 1864 CQCHGHSDRCLPGSGV-----------CVDCQHNTEGAHCERCQAGFVS-----SRDDPS 1907
C C+GH+ C P G C+ C+HNT G +CE+CQ + + D S
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 1908 APCVSCPCPLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFFGNP---L 1960
C C C S +F L G C C+ AG CE C P F+ +P L
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDL 401
Query: 1961 VLGSSCQPCDCS--GNGDPNLLFSDCDP----LTGACRGCLRHTTGPRCEICAPGFYGNA 2014
+ C+ CDC G+ D S DP ++G CR C H G RC+ C GF+G +
Sbjct: 402 RDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLS 460
Query: 2015 LLPG-NCTRCDCTPCGT----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFD-GCGGCR 2068
+ C RC C GT CDP+SG C CK VTGR CDRC GH+G GCR
Sbjct: 461 ISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR 520
Query: 2069 PCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW 2107
PC C A +C +GQCHCR +G +C + PGY+
Sbjct: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 162 bits (411), Expect = 4e-39
Identities = 105/341 (30%), Positives = 145/341 (42%), Gaps = 50/341 (14%)
Query: 589 CSPAGTLPEGCDEA--GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGA 646
C+PA P + G C+C+ G +C++C+ Y P
Sbjct: 292 CAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLP------------------- 332
Query: 647 GGLCRCRPGYTGT--ACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCS-CRPRVT 703
RP G AC++C HG CH L A+ + G C C+
Sbjct: 333 -----WRPAEDGHSHACRKCE--CHGHTHS--CHFDMAVYL-ASGNVSGGVCDGCQHNTA 382
Query: 704 GLRCDTCVPGAYNFP--------YCEAGSCHPAGL-------APVDPALPEAQVPCMCRA 748
G C+ C P Y P C + C P G + DPAL C C+
Sbjct: 383 GRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKE 442
Query: 749 HVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC 808
HV G C +C+ GF+GLS S+ GC RC C+ RGT+ G C P +G C+CK V G+ C
Sbjct: 443 HVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502
Query: 809 ASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
C G +GL D GCR C CD+GGAL C+ TG C CR + G C + ++
Sbjct: 503 DRCLPGHWGLSH-DLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
Query: 869 PDLHHLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQM 909
P L HL E E+ V P E +++ G+ ++
Sbjct: 562 PFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFVRL 602
Score = 143 bits (360), Expect = 4e-33
Identities = 90/255 (35%), Positives = 116/255 (45%), Gaps = 39/255 (15%)
Query: 1404 CAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHV 1463
C +G S +S S C SLS NGA PC C+ G+ C P GGQC C V
Sbjct: 749 CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGV 808
Query: 1464 IGRDCSRCATGYWGF--PNCRPCDCG-----ARLCDELTGQCICPPRTIPPDCLLCQPQT 1516
+GR C CA GY+GF C+ C C + LC++ +GQC+C C CQ
Sbjct: 809 VGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQ 868
Query: 1517 FGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHGYPR-- 1573
+G C C C+G + C+T +G C CR + G C+ C GFHG PR
Sbjct: 869 WG---FPSCRPCVCNGHADE------CNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLP 919
Query: 1574 ----CRPCDCHEAGTAPG-------VC--DPLTGQ--CYCKENVQGPKCDQCSLGTFSLD 1618
CRPC C E PG C D + Q C+C+ G +C+ C+ G F D
Sbjct: 920 YGGQCRPCPCPE---GPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFG-D 975
Query: 1619 AANPKG-CTRCFCFG 1632
+ P G C C C G
Sbjct: 976 PSRPGGRCQLCECSG 990
Score = 141 bits (355), Expect = 1e-32
Identities = 109/344 (31%), Positives = 147/344 (42%), Gaps = 36/344 (10%)
Query: 1747 LEPAYPTPG-HVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSA 1805
L+PA P P + R Q L N R TR + L+ + + AL+ +
Sbjct: 222 LDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRG 281
Query: 1806 -VFLRRVALEVASPAGQGALASNVE--LCLCPASYRGDSCQECAPGFYRDV-----KGLF 1857
F A E A G A A + C+C + RG +C++C FYRD+ +
Sbjct: 282 NCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
Query: 1858 LGRCVPCQCHGHSDRC-----------LPGSGVCVDCQHNTEGAHCERCQAGF----VSS 1902
C C+CHGH+ C GVC CQHNT G HCE C+ F
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 1903 RDDPSAPCVSCPC-PLSVPSNNFAEG---CVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958
DP A C SC C P+ + L QC CK G C++C GFFG
Sbjct: 401 LRDP-AVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459
Query: 1959 PLVLGSSCQPCDCSGNGD-PNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLP 2017
+ C+ C C+ G P + CDP +G+C C R TG C+ C PG +G +
Sbjct: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLSHDL 516
Query: 2018 GNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRCQEGHF 2059
C CDC G CD +G C C+ + GRRC++ Q G+F
Sbjct: 517 LGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 125 bits (313), Expect = 1e-27
Identities = 83/265 (31%), Positives = 109/265 (41%), Gaps = 54/265 (20%)
Query: 445 GRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGN 504
G C C+ N G C+ C + + P S+ R+ C+C +
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRK----------CECHG---HTH 354
Query: 505 ACRKDPRV---------GRCL-CKPNFQGTHCELCAPGFYGPG---------CQPCQCSS 545
+C D V G C C+ N G HCELC P FY C+ C C
Sbjct: 355 SCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDP 414
Query: 546 PGVADD-RCDPD--------TGQCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGCSP 591
G D RCD +GQCRC+ G C +C G+F + C+ C C+
Sbjct: 415 MGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNA 474
Query: 592 AGTLPEG--CD-EAGRCLCQPEFAGPHCDRCRPGY----HGFPNCQACTCDPRGALDQLC 644
GT+P CD +G C C+ G CDRC PG+ H C+ C CD GALD C
Sbjct: 475 RGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQC 534
Query: 645 GAG-GLCRCRPGYTGTACQECSPGF 668
G G C CR G C++ PG+
Sbjct: 535 DEGTGQCHCRQHMVGRRCEQVQPGY 559
Score = 123 bits (309), Expect = 3e-27
Identities = 71/207 (34%), Positives = 90/207 (43%), Gaps = 20/207 (9%)
Query: 671 FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGL 730
+ +PC C+ +GSL + C+P GQC C+P V G RCD C PG Y F +C +
Sbjct: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHE 836
Query: 731 APVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAEC 790
+ + C+CR G CDRC+ G WG PS C C C+ G EC
Sbjct: 837 GALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-PS----CRPCVCN-----GHADEC 886
Query: 791 QPGTGQCF-CKPHVCGQACASCKDGFFGLDQADYFG-CRSCRCDIGGA----LGQSCE-- 842
TG C C+ H G+ C C GF G + Y G CR C C G SC
Sbjct: 887 NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQD 946
Query: 843 --PRTGVCRCRPNTQGPTCSEPARDHY 867
+ VC CR G C A H+
Sbjct: 947 EYSQQIVCHCRAGYTGLRCEACAPGHF 973
Score = 115 bits (289), Expect = 6e-25
Identities = 86/290 (29%), Positives = 109/290 (37%), Gaps = 45/290 (15%)
Query: 1397 SYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCG----CHEVGATGP---- 1448
S + HC A GY + L C A + + +RP G C G P
Sbjct: 949 SQQIVCHCRA-GY------TGLRCEACAPG---HFGDPSRPGGRCQLCECSGNIDPMDPD 998
Query: 1449 TCEPFGGQC-PCHAHVIGRDCSRCATGYWGFP---NCRPCDCGAR-------------LC 1491
C+P GQC C H G C+ C G+ G +C C C C
Sbjct: 999 ACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHC 1058
Query: 1492 DELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCK 1551
D +GQC C P P C C P + GC+ C C PTC+ +GQC
Sbjct: 1059 DPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHP---SRARGPTCNEFTGQCH 1115
Query: 1552 CRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ 1609
CR GR C C G P +C CDC G C TG C C+ V G +CDQ
Sbjct: 1116 CRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
Query: 1610 CSLGTFSLDAANPKGCTRCF-CFGATERCRSSSYTRQEFVDMEGWVLLST 1658
C+ G + A C C CFG +R R + ++ L T
Sbjct: 1176 CARGFSGIFPA----CHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQT 1221
Score = 102 bits (254), Expect = 7e-21
Identities = 70/237 (29%), Positives = 95/237 (40%), Gaps = 61/237 (25%)
Query: 1937 CLCKPGYAGASCERCAPGFFG---NPLVLGSS--CQPCDCSGNG-----DPNLLFSDCDP 1986
C+CK G +CE+C + P G S C+ C+C G+ D + + +
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
Query: 1987 LTGACRGCLRHTTGPRCEICAPGFYGNALL----PGNCTRCDCTPCGTEACDPHSGHCLC 2042
G C GC +T G CE+C P FY + P C CD CDP
Sbjct: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCD--------CDPMGSQ--- 418
Query: 2043 KAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCREC 2102
G RCD + G SGQC C+ +G +C++C
Sbjct: 419 ----DGGRCDSHDDPALGL----------------------VSGQCRCKEHVVGTRCQQC 452
Query: 2103 APGYWGLP---EQGCRRCQC------PGGR-CDPHTGRCNCPPGLSGERCDTCSQQH 2149
G++GL GCRRCQC PG CDP++G C C ++G CD C H
Sbjct: 453 RDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH 509
Score = 82.4 bits (202), Expect = 8e-15
Identities = 48/147 (32%), Positives = 61/147 (41%), Gaps = 22/147 (14%)
Query: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDL 780
E CH GL P + EA C P LS G C C+
Sbjct: 745 ERYQCHEEGLVPSKTSPSEA-----------------CAPLLISLSTLIYNGALPCQCNP 787
Query: 781 RGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS 840
+G+L +EC P GQC CKP V G+ C C G++G GC++C+C GAL
Sbjct: 788 QGSLS--SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPT---GCQACQCSHEGALSSL 842
Query: 841 CEPRTGVCRCRPNTQGPTCSEPARDHY 867
CE +G C CR G C R +
Sbjct: 843 CEKTSGQCLCRTGAFGLRCDRCQRGQW 869
Score = 78.6 bits (192), Expect = 1e-13
Identities = 63/206 (30%), Positives = 78/206 (37%), Gaps = 44/206 (21%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQP 1514
G C C+ H S CA G P A + G CIC T +C CQ
Sbjct: 281 GNCFCYGHA-----SECAPAP-GAP--------AHAEGMVHGACICKHNTRGLNCEQCQD 326
Query: 1515 --QTFGCHPLV-----GCEECNCSGPGIQELTDPTCDTDSGQCK------CRPNVTGRRC 1561
+ P C +C C G D SG C+ N GR C
Sbjct: 327 FYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHC 386
Query: 1562 DTCSPGFHGYPR--------CRPCDCHEAGTAPGV-CDP--------LTGQCYCKENVQG 1604
+ C P F+ P CR CDC G+ G CD ++GQC CKE+V G
Sbjct: 387 ELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVG 446
Query: 1605 PKCDQCSLGTFSLDAANPKGCTRCFC 1630
+C QC G F L ++ GC RC C
Sbjct: 447 TRCQQCRDGFFGLSISDRLGCRRCQC 472
Score = 76.3 bits (186), Expect = 5e-13
Identities = 45/109 (41%), Positives = 52/109 (47%), Gaps = 11/109 (10%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGAT-GPT-CEPFGGQCPCHAHVIGRDCSRCATGYWG 1477
CR+ LS+ G R C C+ G G T C+P G C C V GR C RC G+WG
Sbjct: 452 CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Query: 1478 FPN----CRPCDC--GARL---CDELTGQCICPPRTIPPDCLLCQPQTF 1517
+ CRPCDC G L CDE TGQC C + C QP F
Sbjct: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 45.4 bits (106), Expect = 0.001
Identities = 94/396 (23%), Positives = 153/396 (38%), Gaps = 78/396 (19%)
Query: 2226 RHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAV 2285
RH A+ L + + L + A TR QAS+ +A L A +
Sbjct: 1457 RHTQAELQRALAEGGSILSRVAE--------TRRQASEAQQRAQAALDKANASRGQVEQA 1508
Query: 2286 DRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAA 2345
++ L EL+ + P +++ T R +L P +A +
Sbjct: 1509 NQELQELIQSVKDFLNQEGADPDSIEMVAT-----------RVLELSIPASAEQI----- 1552
Query: 2346 QRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRN 2405
Q L + E++ SL + + LA D + + E L D R A + A D ++A+ +
Sbjct: 1553 QHLAGAIAERVRSLADVDAILARTVGD-VRRAEQLLQDARRARSWAEDEKQKAETV---- 1607
Query: 2406 QERLEEALQRKQELSR--------DNATLQATLHAARDTLASVFRLLHSLDQAKEELERL 2457
Q LEEA QR Q +++ D + TL+ ++ +A R L S + +L+ L
Sbjct: 1608 QAALEEA-QRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDAL 1666
Query: 2458 AASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQR 2517
+L L+R A + +A+ AQ+ QL L + D Q T +
Sbjct: 1667 LEALK------LKRAGNSLAASTAEETAGSAQGRAQEAEQL---LRGPLGDQYQ---TVK 1714
Query: 2518 AIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAML 2577
A+ A Q V AA+ A Q +A + L+ AQ L LE
Sbjct: 1715 ALAERKA-----QGVLAAQARAEQLRDEA---------RDLLQAAQDKLQRLQELE-GTY 1759
Query: 2578 QEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQA 2613
+E +R AL+ QL D LEA +++
Sbjct: 1760 EENER------ALESKAAQL-------DGLEARMRS 1782
Score = 39.3 bits (90), Expect = 0.073
Identities = 90/397 (22%), Positives = 149/397 (37%), Gaps = 60/397 (15%)
Query: 2114 CRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVL 2173
C C G C G+ C G C+ + + + G + H +
Sbjct: 1418 CATSPCGGAGCRDEDGQPRC----GGLSCNGAAATADLAL-----GRARHTQA------- 1461
Query: 2174 LLDDLERA----GALLPAIHEQLRGIN-ASSMAWARLHRLNAS----------IADLQSQ 2218
+L+RA G++L + E R + A A A L + NAS + +L
Sbjct: 1462 ---ELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQS 1518
Query: 2219 LRSPLGPRHETAQQLE-----VLEQQSTSLGQDARRLGG---QAVGTRDQASQLLAGTEA 2270
++ L +E VLE + + + L G + V + +LA T
Sbjct: 1519 VKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVG 1578
Query: 2271 TLGHAKTLLAAIRAVDRTLSE---LMSQTGHLGLANASAPSG------EQLLRTLAEVER 2321
+ A+ LL R R+ +E ++T L A G + + E+
Sbjct: 1579 DVRRAEQLLQDARRA-RSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQ 1637
Query: 2322 LLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGL 2381
L++++ R GA +A + A A Q L + E L L +LA T + A G
Sbjct: 1638 TLYQVQERMAGAERALSSAGERARQ--LDALLEALK-LKRAGNSLAASTAEETAGSAQGR 1694
Query: 2382 MDLREALNRAV--DATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLAS 2439
E L R D + + L R + + A R ++L RD A + L AA+D L
Sbjct: 1695 AQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQL-RDEA--RDLLQAAQDKLQR 1751
Query: 2440 VFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFS 2476
+ L + ++ + LE AA LDG + +Q +
Sbjct: 1752 LQELEGTYEENERALESKAAQLDGLEARMRSVLQAIN 1788
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 324 bits (830), Expect = 1e-87
Identities = 201/555 (36%), Positives = 259/555 (46%), Gaps = 51/555 (9%)
Query: 1456 QCPCHAHVIGRDCSRCATGYWGFPN------CRPCDCG--ARLCDELTGQCI-CPPRTIP 1506
QC C G C C TGY P+ C C C + C+ TG C C T
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 1507 PDCLLCQPQTFGCHPL---VGCEECNCSGPGIQELTDPTC--DTDSGQC--KCRPNVTGR 1559
P C CQP +G C+ C C G TC DTD C P +GR
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 1560 RCDTCSPGFHGYPR----CRP---------CDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
C+ C+PG++G P C+ C+C G+ CD GQC CK V+G
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQCKAQVEGLT 1303
Query: 1607 CDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFV------DMEGWVLLSTDR 1660
C C F L A+NP GC CFC G T++C SS+YTR D +G+ L++ R
Sbjct: 1304 CSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLISTHFAPGDFQGFALVNPQR 1363
Query: 1661 Q---VVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELH 1717
+P E + + + E+F YWQ P +Y GD+V++YGG LRY L
Sbjct: 1364 NSRLTGEFTVEPVPEGAQLSFGNFAQLGHESF---YWQLPETYQGDKVAAYGGKLRYTLS 1420
Query: 1718 SETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNT 1777
G P+ S PDV + GN + + +PA P R + F
Sbjct: 1421 YTA--GPQGSPL-SDPDVQITGNNIMLVASQPALQGPER--RSYEIMFREEFWRRPDGQP 1475
Query: 1778 VSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGA-LASNVELCLCPAS 1836
+RE L+M LA L++L IRA FS + A + V+LEVA P A VE C CP
Sbjct: 1476 ATREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRPRALEVEECRCPPG 1535
Query: 1837 YRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQ 1896
Y G SCQ+CAPG+ R GL+LG C C+C+GHSD C P +G C CQHN G CE C
Sbjct: 1536 YIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCA 1595
Query: 1897 AGFV-SSRDDPSAPCVSCPCPLSVPSNNFAEGC--VLRGGRTQCLCKPGYAGASCERCAP 1953
G+ + C C CPL+ P N F+ C + GG C+PGY G CE+C P
Sbjct: 1596 PGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGP 1655
Query: 1954 GFFGNPLVLGSSCQP 1968
G+ GNP V G C P
Sbjct: 1656 GYVGNPSVQGGQCLP 1670
Score = 311 bits (797), Expect = 8e-84
Identities = 210/629 (33%), Positives = 284/629 (45%), Gaps = 90/629 (14%)
Query: 1456 QCPCHAHVIGRDCSRCATGYWGFPN------CRPCDCG--ARLCDELTGQCI-CPPRTIP 1506
+C C G C C + P C C+C A CD + G C+ C T
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 1507 PDCLLCQPQTFGCH---PLVGCEECNCSGPGIQELTDPTC--DTDSGQCKC---RPNVTG 1558
P C C+ FG C C C TC DTD GQ C P TG
Sbjct: 790 PQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTD-GQATCDACAPGYTG 848
Query: 1559 RRCDTCSPGFHGYP-----RCRPCD-----CHEAGTAPGVCDPLTGQ-CYCKENVQGPKC 1607
RRC++C+PG+ G P +CRP + C E G+ +G+ C CK NV G C
Sbjct: 849 RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMG-----TSGEACRCKNNVVGRLC 903
Query: 1608 DQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHER 1667
++C+ G+F L NP GC +CFC G + C SSS++R Q+
Sbjct: 904 NECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRA---------------QLHGASE 948
Query: 1668 QPGTEMLR--ADLRHVPEAVPEAFP--------------ELYWQAPPSYLGDRVSSYGGT 1711
+PG L A E + P +W P +LGD+V+SYGG
Sbjct: 949 EPGHFSLTNAASTHTTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGE 1008
Query: 1712 LRYELHSETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRH 1771
LR+ + +Q G P+ +P VVLQGN + + P+PG + E ++
Sbjct: 1009 LRFTVTQRSQPGST--PLHGQPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQR 1066
Query: 1772 TETRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGA-LASNVEL 1830
+ + +RE L+M LA ++ L IRA ++Q + + ++++VA P G A VE
Sbjct: 1067 PDGQ-PATREHLLMALAGIDTLLIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQ 1125
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGA 1890
C CP YRG SCQ+C G+ R GL+LG C C CHGHS+ C P +G C CQH+TEG
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGP 1185
Query: 1891 HCERCQAGFV--SSRDDPSAPCVSCPCPLSVPSNNFAEGCVL-RGGRTQC-LCKPGYAGA 1946
CE+CQ G+ + R P C CPC + A C L G C C PG++G
Sbjct: 1186 RCEQCQPGYYGDAQRGTPQ-DCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 1947 SCERCAPGFFGNPLVLGSSCQ---------PCDCSGNGDPNLLFSDCDPLTGACRGCLRH 1997
CERCAPG++GNP G CQ C+C G + S CD G C+ C
Sbjct: 1245 HCERCAPGYYGNP-SQGQPCQRDSQVPGPIGCNCDPQGS---VSSQCD-AAGQCQ-CKAQ 1298
Query: 1998 TTGPRCEICAP-GFYGNALLPGNCTRCDC 2025
G C C P F+ +A P C C C
Sbjct: 1299 VEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 227 bits (579), Expect = 1e-58
Identities = 195/670 (29%), Positives = 274/670 (40%), Gaps = 108/670 (16%)
Query: 1437 PCGCHEVGATGPTCEP----FGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCD---CGAR 1489
PCG E C P GQ C G D C PN PC C +
Sbjct: 284 PCGPQEAACRNGHCIPRDYLCDGQEDCED---GSDELDCGPPPPCEPNEFPCGNGHCALK 340
Query: 1490 L--------CDELTGQCICPPRTIPPDC----------LLCQPQTFGCHPLVGC----EE 1527
L C++ T + CP + C +C P +F C C +E
Sbjct: 341 LWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDE 400
Query: 1528 CNCSGPGIQELTDPTCDTDSGQCKC---------RPNVTGR----------RCDTCSPGF 1568
C P + + GQ P + R R S G
Sbjct: 401 FGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGG 460
Query: 1569 HGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQG-----PKCDQCSLGTFSLDAANPK 1623
G R D E+ C+ + + G P+ C G F L+ +
Sbjct: 461 RGTLIIR--DVKESDQGAYTCEAMNARGMVFGIPDGVLELVPQRGPCPDGHFYLE--HSA 516
Query: 1624 GCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQV------VPHERQPGTEMLRAD 1677
C CFCFG T C+S+ R + + L D+ V QPGT L +
Sbjct: 517 ACLPCFCFGITSVCQSTRRFRDQ-------IRLRFDQPDDFKGVNVTMPAQPGTPPLSST 569
Query: 1678 LRHVPEAVPE----------AFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFV 1727
+ ++ E + +W P +LG++V SYGG+LRY + E RG +
Sbjct: 570 QLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYELARG-MLE 628
Query: 1728 PMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVL 1787
P++ RPDVVL G + PG +++ Q+Q E ++ H E+ V R EL+ VL
Sbjct: 629 PVQ-RPDVVLMGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVH-ESGRPVQRAELLQVL 686
Query: 1788 ASLEQLQIRALFSQISSAVFLRRVALEVA-SPAGQGALASNVELCLCPASYRGDSCQECA 1846
SLE + I+ +++ ++V L +A++ + A A +VE C CP Y G SC+ C
Sbjct: 687 QSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCD 746
Query: 1847 PGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDP 1906
F R G +LG C C C+GH+ C P G C++CQHNTEG C +C+AGF
Sbjct: 747 AHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKA 806
Query: 1907 SA-PCVSCPCPLSVPSNNFAEGCVL-RGGRTQC-LCKPGYAGASCERCAPGFFGNPLVLG 1963
+A C CPCP S F++ C L G+ C C PGY G CE CAPG+ GNP+ G
Sbjct: 807 TATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPG 866
Query: 1964 SSCQP-------CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPG-FYGNAL 2015
C+P CD G+ + ACR C + G C CA G F+ +
Sbjct: 867 GKCRPVNQEIVRCDERGSMGTS---------GEACR-CKNNVVGRLCNECADGSFHLSTR 916
Query: 2016 LPGNCTRCDC 2025
P C +C C
Sbjct: 917 NPDGCLKCFC 926
Score = 134 bits (336), Expect = 2e-30
Identities = 78/212 (36%), Positives = 100/212 (47%), Gaps = 33/212 (15%)
Query: 1936 QCLCKPGYAGASCERCAPGFFGNP--LVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRG 1993
QC C PGY G SC+ C G+ P L LG+ C+ C C G+ + C+P TGAC+G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGT-CERCSCHGHSEA------CEPETGACQG 1177
Query: 1994 CLRHTTGPRCEICAPGFYGNAL--LPGNCTRCDC--TPCGTEAC-------DPHSGHCLC 2042
C HT GPRCE C PG+YG+A P +C C C P +A D H C
Sbjct: 1178 CQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDAC 1237
Query: 2043 KAGVTGRRCDRCQEGHFGFDGCGG-CRPCACGPAAEGSECHPQ---------SGQCHCRP 2092
G +GR C+RC G++G G C+ + P G C PQ +GQC C+
Sbjct: 1238 SPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKA 1297
Query: 2093 GTMGPQCRECAPGYWGLP---EQGCRRCQCPG 2121
G C C P ++ L GC C C G
Sbjct: 1298 QVEGLTCSHCRPHHFHLSASNPDGCLPCFCMG 1329
Score = 129 bits (323), Expect = 7e-29
Identities = 161/621 (25%), Positives = 205/621 (33%), Gaps = 184/621 (29%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
+C C G +C+ C F + P P C CNC GHA+ C
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGT----CSGCNCNGHASSC------------ 773
Query: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC-----ESDF 435
D Y G C++CQH+T G C +C GF+ + CR C C F
Sbjct: 774 ---DPVY---GHCLNCQHNTEGPQCNKCKAGFFGDAMKATATS--CRPCPCPYIDASRRF 825
Query: 436 TDGTCEDLTGRC---YCRPNFSGERCDVCAEGFTGFP-----SCYPTPSSSNDTREQVLP 487
+D D G+ C P ++G RC+ CA G+ G P C P
Sbjct: 826 SDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQ----------- 874
Query: 488 AGQIVNCD-CSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY------GPGCQP 540
+IV CD + GT G ACR CK N G C CA G + GC
Sbjct: 875 --EIVRCDERGSMGTSGEACR---------CKNNVVGRLCNECADGSFHLSTRNPDGCLK 923
Query: 541 CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD 600
C C C T R GA+ + PG+F + G
Sbjct: 924 CFCMG---VSRHC---TSSSWSRAQLHGASEE---PGHFSLTNAASTHTTNEGIFSPTPG 974
Query: 601 EAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
E G F+ H P + P+ R D++ GG R T
Sbjct: 975 ELG-------FSSFHRLLSGPYFWSLPS--------RFLGDKVTSYGGELRF------TV 1013
Query: 661 CQECSPG---FHGFPSCVPCHCSAEGSLHAACDPRSGQCSC-----------RP------ 700
Q PG HG P V + H A +P GQ S RP
Sbjct: 1014 TQRSQPGSTPLHGQPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPAT 1073
Query: 701 ---------------------------RVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV 733
RV+G+ D VP E G
Sbjct: 1074 REHLLMALAGIDTLLIRASYAQQPAESRVSGISMDVAVPE-------ETGQ--------- 1117
Query: 734 DPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEG-----CTRCSCDLRGTLGGVA 788
DPAL Q C C GPSC C G+ P G C RCSC G
Sbjct: 1118 DPALEVEQ--CSCPPGYRGPSCQDCDTGY----TRTPSGLYLGTCERCSCH-----GHSE 1166
Query: 789 ECQPGTGQC-FCKPHVCGQACASCKDGFFG-LDQADYFGCRSCRCDIGGALGQSCEPRTG 846
C+P TG C C+ H G C C+ G++G + C+ C C A GQ+
Sbjct: 1167 ACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAH---- 1222
Query: 847 VCRCRPNTQG-PTCSEPARDH 866
C +T G PTC + H
Sbjct: 1223 --TCFLDTDGHPTCDACSPGH 1241
Score = 112 bits (281), Expect = 5e-24
Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 24/197 (12%)
Query: 1936 QCLCKPGYAGASCERCAPGFF--GNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRG 1993
+C C PGY G SC+ CAPG+ G+ L LG C+ C+C+G+ D C P TGAC
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECNGHSDL------CHPETGACSQ 1581
Query: 1994 CLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHC-LCKA-GVTGRRC 2051
C + G CE+CAPG+YG+A T DC PC +P + C++ G G RC
Sbjct: 1582 CQHNAAGEFCELCAPGYYGDATAG---TPEDCQPCACPLTNPENMFSRTCESLGAGGYRC 1638
Query: 2052 DRCQEGHFGFDGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 2110
C+ G+ G C C P G P+ +G +C P++ Q P E P +P
Sbjct: 1639 TACEPGYTG-QYCEQCGPGYVGNPSVQGGQCLPETNQ--------APLVVEVHPARSIVP 1689
Query: 2111 EQGCRRCQCPGGRCDPH 2127
+ G +C PH
Sbjct: 1690 QGGSHSLRCQVSGSPPH 1706
Score = 111 bits (277), Expect = 2e-23
Identities = 87/288 (30%), Positives = 118/288 (40%), Gaps = 48/288 (16%)
Query: 650 CRCRPGYTGTACQECSPGFHGFPS------CVPCHCSAEGSLHAACDPRSGQCS-CRPRV 702
C C PGY G +CQ+C G+ PS C C C AC+P +G C C+
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSE---ACEPETGACQGCQHHT 1182
Query: 703 TGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV--DPALPEAQVPCM-----------CRAH 749
G RC+ C PG Y + G+ L P DPA +A C C
Sbjct: 1183 EGPRCEQCQPGYYGD--AQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPG 1240
Query: 750 VEGPSCDRCKPGFWGLSPSNPEGCTR---------CSCDLRGTLGGVAECQPGTGQCFCK 800
G C+RC PG++G +PS + C R C+CD +G++ ++C GQC CK
Sbjct: 1241 HSGRHCERCAPGYYG-NPSQGQPCQRDSQVPGPIGCNCDPQGSVS--SQCD-AAGQCQCK 1296
Query: 801 PHVCGQACASCKDGFFGLDQADYFGCRSCRC-DIGGALGQSCEPRTGVCR--CRPNTQGP 857
V G C+ C+ F L ++ GC C C I S R + + QG
Sbjct: 1297 AQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLISTHFAPGDFQGF 1356
Query: 858 TCSEPARDHYLPDLHHLRLELEEAATPEGHAVRFG-FNPLEFENFSWR 904
P R+ L E PEG + FG F L E+F W+
Sbjct: 1357 ALVNPQRNSRLTG------EFTVEPVPEGAQLSFGNFAQLGHESFYWQ 1398
Score = 107 bits (266), Expect = 3e-22
Identities = 70/237 (29%), Positives = 95/237 (40%), Gaps = 48/237 (20%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
QC+C G +C C G+ + P + C+ C+C+GH+ C +PE
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTP----SGLYLGTCERCSCHGHSEAC--EPET------ 1172
Query: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDG-- 438
G C CQHHT G CE+C PG+Y +P C+ C C D G
Sbjct: 1173 ----------GACQGCQHHTEGPRCEQCQPGYYGDAQR--GTPQDCQLCPCYGDPAAGQA 1220
Query: 439 --TC---EDLTGRC-YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIV 492
TC D C C P SG C+ CA G+ G PS R+ +P +
Sbjct: 1221 AHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPS-----QGQPCQRDSQVPGP--I 1273
Query: 493 NCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY------GPGCQPCQC 543
C+C G+ + C G+C CK +G C C P + GC PC C
Sbjct: 1274 GCNCDPQGSVSSQC---DAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 105 bits (263), Expect = 6e-22
Identities = 68/210 (32%), Positives = 88/210 (41%), Gaps = 35/210 (16%)
Query: 1936 QCLCKPGYAGASCERCAPGFF---GNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACR 1992
+C C GY+G SCE C F G P + +C C+C+G+ S CDP+ G C
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYL--GTCSGCNCNGHA------SSCDPVYGHCL 781
Query: 1993 GCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPH-----------SGHCL 2041
C +T GP+C C GF+G+A+ T C PC D G
Sbjct: 782 NCQHNTEGPQCNKCKAGFFGDAM---KATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 838
Query: 2042 CKA---GVTGRRCDRCQEGHFG--FDGCGGCRPC--ACGPAAEGSECHPQSGQCHCRPGT 2094
C A G TGRRC+ C G+ G G CRP E C C+
Sbjct: 839 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNV 898
Query: 2095 MGPQCRECAPGYWGLPEQ---GCRRCQCPG 2121
+G C ECA G + L + GC +C C G
Sbjct: 899 VGRLCNECADGSFHLSTRNPDGCLKCFCMG 928
Score = 100 bits (249), Expect = 3e-20
Identities = 72/227 (31%), Positives = 89/227 (39%), Gaps = 52/227 (22%)
Query: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA 505
+C C P + G C C G+T PS L G C C A
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSG--------------LYLGTCERCSCHG---HSEA 1167
Query: 506 CRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG-------CQPCQC---SSPGVADDRCD 554
C +P G C C+ + +G CE C PG+YG CQ C C + G A C
Sbjct: 1168 C--EPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCF 1225
Query: 555 PDTG---QC-RCRVGFEGATCDRCAPGYFHFPL----CQL---------CGCSPAGTLPE 597
DT C C G G C+RCAPGY+ P CQ C C P G++
Sbjct: 1226 LDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSS 1285
Query: 598 GCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLC 644
CD AG+C C+ + G C CRP H F +P G L C
Sbjct: 1286 QCDAAGQCQCKAQVEGLTCSHCRP--HHF---HLSASNPDGCLPCFC 1327
Score = 96.7 bits (239), Expect = 4e-19
Identities = 63/214 (29%), Positives = 89/214 (41%), Gaps = 44/214 (20%)
Query: 601 EAGRCLCQPEFAGPHCDRCRPGYHGFPN------CQACTCDPRGALDQLCGAGGLCR-CR 653
E +C C P + GP C C GY P+ C+ C+C G + G C+ C+
Sbjct: 1122 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSC--HGHSEACEPETGACQGCQ 1179
Query: 654 PGYTGTACQECSPGFHGFPS--------CVPCH-----------CSAEGSLHAACDPRSG 694
G C++C PG++G PC+ C + H CD
Sbjct: 1180 HHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCD---- 1235
Query: 695 QCSCRPRVTGLRCDTCVPGAYNFPY----CEAGSCHPAGLA-PVDP-----ALPEAQVPC 744
+C P +G C+ C PG Y P C+ S P + DP + +A C
Sbjct: 1236 --ACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQC 1293
Query: 745 MCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
C+A VEG +C C+P + LS SNP+GC C C
Sbjct: 1294 QCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 95.9 bits (237), Expect = 7e-19
Identities = 64/193 (33%), Positives = 88/193 (45%), Gaps = 32/193 (16%)
Query: 542 QCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGY------FHFPLCQLCGCSPAGTL 595
+ + PG ++ + +CRC G+ G +C CAPGY + C+LC C+ L
Sbjct: 1512 EVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL 1571
Query: 596 PEGCDEAGRCL-CQPEFAGPHCDRCRPGYHGFP------NCQACTC---DPRGALDQLC- 644
E G C CQ AG C+ C PGY+G +CQ C C +P + C
Sbjct: 1572 CH--PETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCE 1629
Query: 645 --GAGGL--CRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGS-------LHAACD--P 691
GAGG C PGYTG C++C PG+ G PS C E + +H A P
Sbjct: 1630 SLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVP 1689
Query: 692 RSGQCSCRPRVTG 704
+ G S R +V+G
Sbjct: 1690 QGGSHSLRCQVSG 1702
Score = 94.0 bits (232), Expect = 3e-18
Identities = 63/179 (35%), Positives = 79/179 (44%), Gaps = 30/179 (16%)
Query: 2000 GPRCEICAPGFYG--NALLPGNCTRCDCTPCGTEACDPHSGHCL-CKAGVTGRRCDRCQE 2056
GP C+ C G+ + L G C RC C +EAC+P +G C C+ G RC++CQ
Sbjct: 1134 GPSCQDCDTGYTRTPSGLYLGTCERCSCHG-HSEACEPETGACQGCQHHTEGPRCEQCQP 1192
Query: 2057 GHFGFDGCG---GCRPCAC-GPAAEGSECHP------QSGQCH-CRPGTMGPQCRECAPG 2105
G++G G C+ C C G A G H C C PG G C CAPG
Sbjct: 1193 GYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPG 1252
Query: 2106 YWGLPEQG--CRR-CQCPGG---RCDPH---------TGRCNCPPGLSGERCDTCSQQH 2149
Y+G P QG C+R Q PG CDP G+C C + G C C H
Sbjct: 1253 YYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHH 1311
Score = 90.1 bits (222), Expect = 4e-17
Identities = 50/147 (34%), Positives = 69/147 (46%), Gaps = 25/147 (17%)
Query: 512 VGRCLCKPNFQGTHCELCAPGFYGPG-------CQPCQCSSPGVADDRCDPDTGQC-RCR 563
V C C P + G C+ CAPG+ G C+ C+C+ D C P+TG C +C+
Sbjct: 1527 VEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNG---HSDLCHPETGACSQCQ 1583
Query: 564 VGFEGATCDRCAPGYFHFPL------CQLCGC---SPAGTLPEGCDEAG----RC-LCQP 609
G C+ CAPGY+ CQ C C +P C+ G RC C+P
Sbjct: 1584 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 610 EFAGPHCDRCRPGYHGFPNCQACTCDP 636
+ G +C++C PGY G P+ Q C P
Sbjct: 1644 GYTGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 87.8 bits (216), Expect = 2e-16
Identities = 54/173 (31%), Positives = 77/173 (44%), Gaps = 33/173 (19%)
Query: 299 RCVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
RC CHGH++AC +P C CQH+T G C++C PG+ + A + +CQ
Sbjct: 1158 RCSCHGHSEAC------EPETGACQGCQHHTEGPRCEQCQPGY----YGDAQRGTPQDCQ 1207
Query: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
C CYG DP + + LD G C C +G +CERC PG+Y +P+
Sbjct: 1208 LCPCYG-------DPAAGQAAHTCFLD--TDGHPTCDACSPGHSGRHCERCAPGYYGNPS 1258
Query: 418 HPLDSPHVCRR---------CNCESDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
C+R CNC+ + + D G+C C+ G C C
Sbjct: 1259 ----QGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHC 1307
Score = 83.6 bits (205), Expect = 3e-15
Identities = 59/205 (28%), Positives = 78/205 (38%), Gaps = 43/205 (20%)
Query: 512 VGRCLCKPNFQGTHCELCAPGF-------YGPGCQPCQCSSPGVADDRCDPDTGQC-RCR 563
V C C + G CE C F Y C C C+ CDP G C C+
Sbjct: 728 VEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHA---SSCDPVYGHCLNCQ 784
Query: 564 VGFEGATCDRCAPGYFHFPL------CQLCGC---SPAGTLPEGC----DEAGRC-LCQP 609
EG C++C G+F + C+ C C + + C D C C P
Sbjct: 785 HNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 844
Query: 610 EFAGPHCDRCRPGYHGFP----------NCQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
+ G C+ C PGY G P N + CD RG++ +G CRC+ G
Sbjct: 845 GYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGT---SGEACRCKNNVVGR 901
Query: 660 ACQECSPG-FH----GFPSCVPCHC 679
C EC+ G FH C+ C C
Sbjct: 902 LCNECADGSFHLSTRNPDGCLKCFC 926
Score = 80.1 bits (196), Expect = 4e-14
Identities = 52/199 (26%), Positives = 77/199 (38%), Gaps = 42/199 (21%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
+C C G +C C PG+ + + C+ C C GH+ C+ PE
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLCH--PET------ 1576
Query: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC----ESDFT 436
G C CQH+ G CE C PG+Y +P C+ C C +
Sbjct: 1577 ----------GACSQCQHNAAGEFCELCAPGYYGDAT--AGTPEDCQPCACPLTNPENMF 1624
Query: 437 DGTCEDLTGRCY----CRPNFSGERCDVCAEGFTGFPS-----CYPTPSSSNDTRE---- 483
TCE L Y C P ++G+ C+ C G+ G PS C P + + E
Sbjct: 1625 SRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPA 1684
Query: 484 -QVLPAGQIVNCDCSAAGT 501
++P G + C +G+
Sbjct: 1685 RSIVPQGGSHSLRCQVSGS 1703
Score = 77.8 bits (190), Expect = 2e-13
Identities = 62/173 (35%), Positives = 77/173 (44%), Gaps = 32/173 (18%)
Query: 1991 CRGCLRHTTGPRCEICAPGFY---GNALLPGNCTRCDCTPCGTEACDPHSGHCL-CKAGV 2046
CR C +G CE C F G L G C+ C+C + +CDP GHCL C+
Sbjct: 731 CR-CPIGYSGLSCESCDAHFTRVPGGPYL-GTCSGCNCNGHAS-SCDPVYGHCLNCQHNT 787
Query: 2047 TGRRCDRCQEGHFGFD---GCGGCRPCACGPAAEGSECHPQS------GQCHC---RPGT 2094
G +C++C+ G FG CRPC C P + S + GQ C PG
Sbjct: 788 EGPQCNKCKAGFFGDAMKATATSCRPCPC-PYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 2095 MGPQCRECAPGYWGLPEQGCRRCQCPGGRCDP---HTGRCN--CPPGLSGERC 2142
G +C CAPGY G P Q PGG+C P RC+ G SGE C
Sbjct: 847 TGRRCESCAPGYEGNPIQ-------PGGKCRPVNQEIVRCDERGSMGTSGEAC 892
Score = 75.1 bits (183), Expect = 1e-12
Identities = 58/172 (33%), Positives = 73/172 (42%), Gaps = 33/172 (19%)
Query: 300 CVCHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C C+GHA +C DP C CQHNT G C++C GF K ATA S C+
Sbjct: 764 CNCNGHASSC------DPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMK-ATATS---CRP 813
Query: 359 CNCYGHATDCYYDPEVD-RRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
C C P +D RR S + G C C TG CE C PG+ +P
Sbjct: 814 CPC----------PYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPI 863
Query: 418 HPLDSPHVCRRCN-----CESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEG 464
P CR N C+ + GT + C C+ N G C+ CA+G
Sbjct: 864 QPGGK---CRPVNQEIVRCDERGSMGTSGE---ACRCKNNVVGRLCNECADG 909
Score = 70.9 bits (172), Expect = 2e-11
Identities = 51/166 (30%), Positives = 62/166 (37%), Gaps = 46/166 (27%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C P + G C CA G+T S L G C+C+ G++
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSG--------------LYLGHCELCECN-----GHSD 1570
Query: 507 RKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG-------CQPC-------------QCSS 545
P G C C+ N G CELCAPG+YG CQPC C S
Sbjct: 1571 LCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCES 1630
Query: 546 PGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSP 591
G RC C G+ G C++C PGY P Q C P
Sbjct: 1631 LGAGGYRC------TACEPGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 70.5 bits (171), Expect = 3e-11
Identities = 54/197 (27%), Positives = 78/197 (39%), Gaps = 24/197 (12%)
Query: 396 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRC-YCRPNFS 454
C G++C+ C PG+ R+ + L H C C C C TG C C+ N +
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSG-LYLGH-CELCECNGH--SDLCHPETGACSQCQHNAA 1587
Query: 455 GERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGR 514
GE C++CA G+ G + TP + + + C + G G C
Sbjct: 1588 GEFCELCAPGYYGDATA-GTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA------ 1640
Query: 515 CLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRC 574
C+P + G +CE C PG+ G +P V +C P+T Q V A
Sbjct: 1641 --CEPGYTGQYCEQCGPGYVG---------NPSVQGGQCLPETNQAPLVVEVHPAR-SIV 1688
Query: 575 APGYFHFPLCQLCGCSP 591
G H CQ+ G P
Sbjct: 1689 PQGGSHSLRCQVSGSPP 1705
Score = 68.9 bits (167), Expect = 9e-11
Identities = 50/149 (33%), Positives = 66/149 (44%), Gaps = 29/149 (19%)
Query: 2040 CLCKAGVTGRRCDRCQEGHF----GFDGCGGCRPCACGPAAEGSECHPQSGQC-HCRPGT 2094
C C G +G C+ C + HF G G C C C A S C P G C +C+ T
Sbjct: 731 CRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCNCNGHA--SSCDPVYGHCLNCQHNT 787
Query: 2095 MGPQCRECAPGYWG----LPEQGCRRCQCP--------GGRCDPHT---GRCN-CPPGLS 2138
GPQC +C G++G CR C CP C T C+ C PG +
Sbjct: 788 EGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYT 847
Query: 2139 GERCDTCSQQHQ-VPV-PGG---PVGHSI 2162
G RC++C+ ++ P+ PGG PV I
Sbjct: 848 GRRCESCAPGYEGNPIQPGGKCRPVNQEI 876
Score = 68.2 bits (165), Expect = 1e-10
Identities = 42/148 (28%), Positives = 59/148 (39%), Gaps = 24/148 (16%)
Query: 601 EAGRCLCQPEFAGPHCDRCRPGYHG------FPNCQACTCDPRGALDQLCG--AGGLCRC 652
E C C P + G C C PGY +C+ C C+ LC G +C
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS---DLCHPETGACSQC 1582
Query: 653 RPGYTGTACQECSPGFHGFPS------CVPCHC---SAEGSLHAACDPRSG---QCS-CR 699
+ G C+ C+PG++G + C PC C + E C+ +C+ C
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACE 1642
Query: 700 PRVTGLRCDTCVPGAYNFPYCEAGSCHP 727
P TG C+ C PG P + G C P
Sbjct: 1643 PGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 66.6 bits (161), Expect = 4e-10
Identities = 41/119 (34%), Positives = 56/119 (47%), Gaps = 20/119 (16%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C C+GH+D C P C+ CQHN G C+ C PG+ + ATA + +CQ
Sbjct: 1563 CECNGHSDLC------HPETGACSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQP 1612
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
C C +PE R +SL GG C C+ TG CE+C PG+ +P+
Sbjct: 1613 CAC------PLTNPENMFSRTCESLGA---GGYRCTACEPGYTGQYCEQCGPGYVGNPS 1662
Score = 61.2 bits (147), Expect = 2e-08
Identities = 39/135 (28%), Positives = 54/135 (40%), Gaps = 16/135 (11%)
Query: 695 QCSCRPRVTGLRCDTCVPG------AYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRA 748
+C C P GL C C PG +CE C+ D PE C+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHS----DLCHPETGACSQCQH 1584
Query: 749 HVEGPSCDRCKPGFWG-LSPSNPEGCTRCSCDLRGTLGGVAE-CQ---PGTGQC-FCKPH 802
+ G C+ C PG++G + PE C C+C L + C+ G +C C+P
Sbjct: 1585 NAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPG 1644
Query: 803 VCGQACASCKDGFFG 817
GQ C C G+ G
Sbjct: 1645 YTGQYCEQCGPGYVG 1659
Score = 57.0 bits (136), Expect = 3e-07
Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 2074 PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW----GLPEQGCRRCQCPG--GRCDPH 2127
P G + + QC C PG GP C++C GY GL C RC C G C+P
Sbjct: 1112 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPE 1171
Query: 2128 TGRC-NCPPGLSGERCDTC 2145
TG C C G RC+ C
Sbjct: 1172 TGACQGCQHHTEGPRCEQC 1190
Score = 48.9 bits (115), Expect = 9e-05
Identities = 45/171 (26%), Positives = 80/171 (46%), Gaps = 23/171 (13%)
Query: 3517 PLEAGLFFPGSGGVITLDLPG----ATLPDVG--LELEVRPLAVTGLIF----HLGQA-R 3565
P + G +F G L PG +LP+V +ELEVR +GL+ +G+A +
Sbjct: 4199 PGQYGAYFHDDG---FLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQ 4255
Query: 3566 TPPYLQLQVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQ- 3624
++ L + + ++ R G+GE P + DG+WHR+ ++ G ++VD +
Sbjct: 4256 GKDFISLGLQDGHLVFRYQLGSGEARLVSEDP--INDGEWHRVTALREGRRGSIQVDGEE 4313
Query: 3625 --SNHTVGPLLAAAAGAPAPLYLGGLPEPMAVQ--PWPPAYCGCMRRLAVN 3671
S + GP A A +Y+GG P+ + + GC++ L ++
Sbjct: 4314 LVSGRSPGP--NVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLH 4362
Score = 48.1 bits (113), Expect = 2e-04
Identities = 38/114 (33%), Positives = 43/114 (37%), Gaps = 17/114 (14%)
Query: 2036 HSGHCLCKAGVTGRRCDRCQE--GHFGFDGCGGCRPCACGPAAEGSECHPQSG---QCHC 2090
H C+ + V G+R D G G C PC P G+ C P QC C
Sbjct: 4072 HFRGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLC 4131
Query: 2091 RPGTMGPQCRECAPGYWGLPEQGCR-RCQC-PGGRCDPHTGRCNCPPGLSGERC 2142
R G G C E C+ R C GG C RC C PG SG RC
Sbjct: 4132 RDGFKGDLCEH--------EENPCQLREPCLHGGTCQGT--RCLCLPGFSGPRC 4175
Score = 46.6 bits (109), Expect = 5e-04
Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 7/144 (4%)
Query: 3365 SLSMHVLPRSSRGLLLF----TARLRPGSPSLALFLSNGHFVAQMEGLGTRLRAQSRQRS 3420
++ + V ++ GLLL+ G ++L L +GH V + + R S
Sbjct: 4229 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPI 4288
Query: 3421 RPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHTLFVGGLPASSHSSK 3480
G WH+V+ E R + DG S P ++++GG P + +
Sbjct: 4289 NDGEWHRVTALREGRRGSIQVDGEELVSGRSP---GPNVAVNAKGSVYIGGAPDVATLTG 4345
Query: 3481 LPVTVGFSGCVKRLRLHGRPLGAP 3504
+ G +GCVK L LH GAP
Sbjct: 4346 GRFSSGITGCVKNLVLHSARPGAP 4369
Score = 46.2 bits (108), Expect = 6e-04
Identities = 31/88 (35%), Positives = 36/88 (40%), Gaps = 13/88 (14%)
Query: 2019 NCTRCDCTPC--GTEACDPHSGH--CLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGP 2074
+C C PC G + D S C+C AG TG RC+ Q H C P ACGP
Sbjct: 3844 HCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH--------CHPEACGP 3895
Query: 2075 AAEGSECHPQSG-QCHCRPGTMGPQCRE 2101
A G C C G G +C E
Sbjct: 3896 DATCVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 44.7 bits (104), Expect = 0.002
Identities = 41/156 (26%), Positives = 50/156 (32%), Gaps = 38/156 (24%)
Query: 1438 CGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWGFPNC-RPCDCGARLCDELT 1495
C E C P G C C + G C CA GY+G P DC
Sbjct: 1560 CELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDC--------- 1610
Query: 1496 GQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPN 1555
C CP L P+ + C G G T C P
Sbjct: 1611 QPCACP---------LTNPEN------MFSRTCESLGAGGYRCT-----------ACEPG 1644
Query: 1556 VTGRRCDTCSPGFHGYPRCRPCDC-HEAGTAPGVCD 1590
TG+ C+ C PG+ G P + C E AP V +
Sbjct: 1645 YTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVE 1680
Score = 44.3 bits (103), Expect = 0.002
Identities = 29/98 (29%), Positives = 38/98 (38%), Gaps = 10/98 (10%)
Query: 1403 HC--AAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCH 1460
HC A GY+ +PS R++ G C C G+ C+ GQC C
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVP-------GPIGCNCDPQGSVSSQCDA-AGQCQCK 1296
Query: 1461 AHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQC 1498
A V G CS C ++ P C C +T QC
Sbjct: 1297 AQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQC 1334
Score = 43.5 bits (101), Expect = 0.004
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 796 QCFCKPHVCGQACASCKDGFFGLDQADYFG-CRSCRCDIGGALGQSCEPRTGVC-RCRPN 853
+C C P G +C C G+ Y G C C C+ L C P TG C +C+ N
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL---CHPETGACSQCQHN 1585
Query: 854 TQGPTCSEPARDHY 867
G C A +Y
Sbjct: 1586 AAGEFCELCAPGYY 1599
Score = 41.2 bits (95), Expect = 0.019
Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 28/140 (20%)
Query: 1973 GNGDPNLLFSDCDPLTGACRGCLRHTT--GPRCEICAPGFYGNALLPGNCTRCDCTPCGT 2030
G +P++ S ++ RGC+ + G R ++ F G+ + G C D +PC
Sbjct: 4055 GGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTY-SFLGSQGI-GQCY--DSSPCER 4110
Query: 2031 EACD---------PHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSEC 2081
+ C + CLC+ G G C+ + + C PC G +G+
Sbjct: 4111 QPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEE------NPCQLREPCLHGGTCQGT-- 4162
Query: 2082 HPQSGQCHCRPGTMGPQCRE 2101
+C C PG GP+C++
Sbjct: 4163 -----RCLCLPGFSGPRCQQ 4177
Score = 40.4 bits (93), Expect = 0.033
Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 4/89 (4%)
Query: 575 APGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTC 634
A G H P C+ C G + + C+C F G C+ + H P +AC
Sbjct: 3839 AHGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQ-ALHCHP--EACGP 3895
Query: 635 DPRGALDQLCGAGGLCRCRPGYTGTACQE 663
D +++ G G CRC G +G C+E
Sbjct: 3896 DAT-CVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 40.4 bits (93), Expect = 0.033
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 8/88 (9%)
Query: 624 HGFPNCQACT---CDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCS 680
HG +C C C G + +C C G+TG+ C+ S H C P C
Sbjct: 3840 HGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEH-SQALH----CHPEACG 3894
Query: 681 AEGSLHAACDPRSGQCSCRPRVTGLRCD 708
+ + D R C C +GLRC+
Sbjct: 3895 PDATCVNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 40.4 bits (93), Expect = 0.033
Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 14/114 (12%)
Query: 447 CYCRPNFSGERCDVCAE--GFTGFPSCYPTPSSSNDTREQ---VLPAGQI-VNCDCSAAG 500
C + +G+R D+ G G CY + + +PAG+ C C G
Sbjct: 4076 CVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRD-G 4134
Query: 501 TQGNACRKDPRVGR----CLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVAD 550
+G+ C + + CL QGT C LC PGF GP CQ Q S G+A+
Sbjct: 4135 FKGDLCEHEENPCQLREPCLHGGTCQGTRC-LCLPGFSGPRCQ--QGSGHGIAE 4185
Score = 38.5 bits (88), Expect = 0.12
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 18/166 (10%)
Query: 3526 GSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTP--PYLQLQVTEKQVLLRA 3583
G+G + L T ++ L++E +PLA G++ G P ++ L + + R
Sbjct: 3934 GAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRY 3993
Query: 3584 DDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAP--- 3640
+ G+G P L G+WHR++ + L V+ P+L ++ G
Sbjct: 3994 ELGSGLAVLRSAEPLAL--GRWHRVSAERLNKDGSLRVNGGR-----PVLRSSPGKSQGL 4046
Query: 3641 ---APLYLGGLPEPMAVQP---WPPAYCGCMRRLAVNRSPVAMTRS 3680
LYLGG+ + + P + GC+ ++VN + +T S
Sbjct: 4047 NLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYS 4092
Score = 37.7 bits (86), Expect = 0.21
Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 3366 LSMHVLPRSSRGLLLFTA-RLRPGSPSLALFLSNGHFVAQMEGLGTRLRA-QSRQRSRPG 3423
L + P + G+LLF+ + P ++L + GH + E LG+ L +S + G
Sbjct: 3953 LDVEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYE-LGSGLAVLRSAEPLALG 4011
Query: 3424 RWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPHT-LFVGGL-PASSHSSKL 3481
RWH+VS L +G R + P + QG HT L++GG+ P+ S
Sbjct: 4012 RWHRVSAERLNKDGSLRVNGGRPVLRSSPGKS-QGL---NLHTLLYLGGVEPSVPLSPAT 4067
Query: 3482 PVTVGFSGCVKRLRLHGRPL 3501
++ F GCV + ++G+ L
Sbjct: 4068 NMSAHFRGCVGEVSVNGKRL 4087
Score = 37.4 bits (85), Expect = 0.28
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 12/61 (19%)
Query: 559 QCRCRVGFEGATCDRCAPGYFHFPLCQLCG-CSPAGTLPEGCDEAGRCLCQPEFAGPHCD 617
QC CR GF+G C+ CQL C GT + RCLC P F+GP C
Sbjct: 4128 QCLCRDGFKGDLCEH------EENPCQLREPCLHGGTC-----QGTRCLCLPGFSGPRCQ 4176
Query: 618 R 618
+
Sbjct: 4177 Q 4177
Score = 36.6 bits (83), Expect = 0.47
Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 20/68 (29%)
Query: 2098 QCRECAPGYWGLPEQG----------------CRRCQCPG--GRCDPHTGRCN-CPPGLS 2138
+CR C PGY GL Q C C+C G C P TG C+ C +
Sbjct: 1529 ECR-CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAA 1587
Query: 2139 GERCDTCS 2146
GE C+ C+
Sbjct: 1588 GEFCELCA 1595
Score = 36.2 bits (82), Expect = 0.62
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 12/52 (23%)
Query: 2131 CNCPPGLSGERCDTCSQQHQVPVPGGPV----------GHSIHCE-VCDHCV 2171
C CP G SG C++C H VPGGP GH+ C+ V HC+
Sbjct: 731 CRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCL 781
Score = 33.9 bits (76), Expect = 3.1
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 1440 CHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQC 1498
C E G+ G + G C C +V+GR C+ CA G + P C C ++ C
Sbjct: 879 CDERGSMGTS----GEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHC 933
Score = 33.9 bits (76), Expect = 3.1
Identities = 39/180 (21%), Positives = 74/180 (41%), Gaps = 28/180 (15%)
Query: 3535 LPGATLPDVGLELEV----RPLAVTGLIFHLGQART-----------PPYLQLQVTEKQV 3579
LP T+ D + E+ RP + G++ + GQ R P ++ + +
Sbjct: 3674 LPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRP 3733
Query: 3580 LLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKS---GNVLRLEVDAQSNHTVGPLLAAA 3636
R D G+G ++ P+ L G +H + +++S G+++ ++ + + G
Sbjct: 3734 EFRFDAGSG--MATIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKF--QG 3789
Query: 3637 AGAPAPLYLGGLPEPMAVQP--WPPAYCGCMRRLAVNRSPVAM-TRSVEVHGAVGASGCP 3693
LYLGG P+ A+ + GC+R L + + ++ H G S CP
Sbjct: 3790 LDLNEELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAH---GISHCP 3846
Score = 33.9 bits (76), Expect = 3.1
Identities = 41/134 (30%), Positives = 48/134 (35%), Gaps = 39/134 (29%)
Query: 344 PWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTY-----QGGGVCID--- 395
P PAT SA H C + V+ +R LD TY QG G C D
Sbjct: 4062 PLSPATNMSA----------HFRGCVGEVSVNGKR----LDLTYSFLGSQGIGQCYDSSP 4107
Query: 396 -----CQHHTTGVNCER------CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLT 444
CQH T + C GF ++P R E GTC+
Sbjct: 4108 CERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLR----EPCLHGGTCQGT- 4162
Query: 445 GRCYCRPNFSGERC 458
RC C P FSG RC
Sbjct: 4163 -RCLCLPGFSGPRC 4175
Score = 33.5 bits (75), Expect = 4.0
Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 25/105 (23%)
Query: 2114 CRRCQCP-GGRCDPHTGR---CNCPPGLSGERCDTCSQQHQVPVPGGP----------VG 2159
CR C GG+C C CP G +G RC+ H P GP G
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRG 3907
Query: 2160 HSIHCEV------CDHCVVLLLDDLERAGA--LLPAI---HEQLR 2193
++ C + C+ V + L AG+ LPA+ H +LR
Sbjct: 3908 YTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELR 3952
Score = 33.5 bits (75), Expect = 4.0
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 42/115 (36%)
Query: 558 GQCRCRVGFEGATCDR--CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPH 615
GQC ++ + C+R C G C PAG + +CLC+ F G
Sbjct: 4100 GQC-----YDSSPCERQPCQHG---------ATCMPAG------EYEFQCLCRDGFKGDL 4139
Query: 616 CDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCR-----CRPGYTGTACQECS 665
C+ H CQ L + C GG C+ C PG++G CQ+ S
Sbjct: 4140 CE------HEENPCQ---------LREPCLHGGTCQGTRCLCLPGFSGPRCQQGS 4179
Score = 33.1 bits (74), Expect = 5.2
Identities = 23/90 (25%), Positives = 33/90 (36%), Gaps = 17/90 (18%)
Query: 536 PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTL 595
P C+ C + G D + + C C GF G+ C+ + H
Sbjct: 3846 PTCRDRPCQNGGQCHDS-ESSSYVCVCPAGFTGSRCEHSQALHCH--------------- 3889
Query: 596 PEGCDEAGRCLCQPEFAGPHCDRCRPGYHG 625
PE C C+ +P+ G C RC G G
Sbjct: 3890 PEACGPDATCVNRPDGRGYTC-RCHLGRSG 3918
Score = 33.1 bits (74), Expect = 5.2
Identities = 17/58 (29%), Positives = 22/58 (37%), Gaps = 4/58 (6%)
Query: 515 CLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD 572
C+C F G+ CE C P C +R D CRC +G G C+
Sbjct: 3869 CVCPAGFTGSRCEHSQ----ALHCHPEACGPDATCVNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 32.7 bits (73), Expect = 6.8
Identities = 27/92 (29%), Positives = 31/92 (33%), Gaps = 18/92 (19%)
Query: 2060 GFDGCGGCRPCACGPAAEGSECHPQSGQ---CHCRPGTMGPQCR-----ECAPGYWGLPE 2111
G C CR P G +CH C C G G +C C P G P+
Sbjct: 3841 GISHCPTCRD---RPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACG-PD 3896
Query: 2112 QGCRRCQCPGGRCDPHTGRCNCPPGLSGERCD 2143
C R D C C G SG RC+
Sbjct: 3897 ATC------VNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 32.3 bits (72), Expect = 8.9
Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 2793 DYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQ 2852
D++ + L+D + + YQLG ++S D ++ V+ R + G + V E +
Sbjct: 4258 DFISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSG 4317
Query: 2853 ETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIE 2901
+ G VA A+G + Y+GG P T G GC++
Sbjct: 4318 RSPGPNVAVNAKGSV---------YIGGAPDVATLTGGRFSSGITGCVK 4357
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 323 bits (829), Expect = 1e-87
Identities = 215/648 (33%), Positives = 304/648 (46%), Gaps = 105/648 (16%)
Query: 21 PLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGAR--IAASATCGEEAPARGSPRPTE 78
P L+ AL G A++ G + +PP +L G + AS+TCG P
Sbjct: 3 PFFLLCFALPGLLHAQQACSRG-ACYPPVGDLLVGRTRFLRASSTCGLTKP--------- 52
Query: 79 DLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASN-------AIDGTERWWQSP 131
+ YC T G++ C +S + H + + G RWWQS
Sbjct: 53 ETYC--------------TQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQ 98
Query: 132 PLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASS 191
+ N V++ LDL + F + V+++F P P ++ERS DFG+T++ +Q+ A+
Sbjct: 99 N-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQYLAA- 151
Query: 192 KRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIV----VSLVNGRPGAMNFSYS 247
DC F R C + R NG V + LV+G P S
Sbjct: 152 --DCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMDLVSGIPATQ----S 205
Query: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHAD 307
++E + TN+R+ F R L + + P+ YY++ + + G C CHGHAD
Sbjct: 206 QKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGHAD 257
Query: 308 ACDAKD-----PTDPFRLQ--CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
C K P+ ++ C CQHNT G C+RC P +N +PW+PA A+ECQ C+
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
C GH+ C++DP V ASQ G Y GGVC +C+ HT G NCERC ++R+
Sbjct: 318 CNGHSETCHFDPAV--FAASQ---GAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
Query: 421 DSPHVCRRCNCESD--FTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSS 478
C C C+ D C+ +TG+C C+ + GERCD+C GFTG Y P
Sbjct: 371 SIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL--TYANPQGC 428
Query: 479 NDTREQVLPAGQIVNCDCSAAGTQGN-ACRKDPRVGRCLCKPNFQGTHCELCAPGFY--- 534
+ CDC+ G++ + C D GRCLC PN G C+ CAP +
Sbjct: 429 H-------------RCDCNILGSRRDMPC--DEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
Query: 535 -GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCA----PGYFHFPL---CQL 586
G GC+PC C +C+ TGQC CR GF G C A P + + C+
Sbjct: 474 SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA 533
Query: 587 CGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGY-HGFPNCQAC 632
C C GT GCD+A GRCLC+P GP CD+C+ GY + +P C AC
Sbjct: 534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Score = 216 bits (550), Expect = 3e-55
Identities = 256/957 (26%), Positives = 363/957 (37%), Gaps = 176/957 (18%)
Query: 1864 CQCHGHSDRCLPGSG-------------VCVDCQHNTEGAHCERCQAGFVSSRD------ 1904
C CHGH+DRC P G VCV CQHNT G +CERC A F ++R
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERC-APFYNNRPWRPAEG 307
Query: 1905 DPSAPCVSCPCPLSVPSNNFAEGC--------VLRG--GRTQCLCKPGYAGASCERCAPG 1954
+ C C C N +E C +G G C+ G +CERC
Sbjct: 308 QDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 1955 FFGNP---LVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+F N + +C C+C +G + + CDP+TG C C H G RC++C PGF
Sbjct: 362 YFRNRRPGASIQETCISCECDPDGA--VPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
Query: 2012 GNALL-PGNCTRCDCTPCGTEA---CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGC 2067
G P C RCDC G+ CD SG CLC V G +CD+C H+ GC
Sbjct: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGC 478
Query: 2068 RPCACGPAAEGS-ECHPQSGQCHCRPGTMGPQC-----RECAPGYWGLPEQGCRRCQC-- 2119
PCAC P S +C+ +GQC CR G G C R+C +G GCR C C
Sbjct: 479 EPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
Query: 2120 ---PGGRCDPHTGRCNCPPGLSGERCDTCSQQH--QVPVPGGPVGHSIHCEVCDHCVVLL 2174
G CD +GRC C PGL+G RCD C + + + PV C C C
Sbjct: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPV----------CVACHPCFQTY 588
Query: 2175 LDDLE----RAGALLPAIHEQLRGINASSMAWA-RLHRLNASIADLQSQLRSPLGPRHET 2229
DL R G L A G A R+ + I +++ L SP E
Sbjct: 589 DADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEV 648
Query: 2230 AQ---------------QLEV-LEQQSTSLGQDARRLGGQAVG-------TRDQ------ 2260
AQ QL++ LE+++ SL +D L G R+Q
Sbjct: 649 AQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISS 708
Query: 2261 ------------ASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPS 2308
A + A + + LL +R R L+ Q G G +P
Sbjct: 709 ADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAG--GGGGTGSPK 766
Query: 2309 GEQLLRTLAEVERLLWEM-----RARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEEN 2363
L ++ + L +R + + EL A L
Sbjct: 767 LVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAG 826
Query: 2364 QA--LATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSR 2421
A +A Q ++L A L R+ + A ++ A ++ S Q + + ++
Sbjct: 827 GAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEES---ASQIQSSAQRLETQVSASRSQMEE 883
Query: 2422 DNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSK 2481
D + + RD L ++ + E + L D A +LQ+M
Sbjct: 884 DVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA--TVLQKMNEI------ 935
Query: 2482 LRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQ 2541
+A A +L + L LS D+ + R Q EA A SR ED G
Sbjct: 936 -------QAIAARLPNVDLVLSQTKQDIARARRLQ--AEAEEARSRAHAVEGQVEDVVGN 986
Query: 2542 ------ALQQADHTWATVVR-----QGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAAL 2590
ALQ+A T R Q V QQ+L + L +M ++ LG W +
Sbjct: 987 LRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQ---LGDFWTRM 1043
Query: 2591 QGARTQLRDVRAKKDQLEAHIQAA--QAMLAMDTDETSK-KIAHAK----------AVAA 2637
+ R Q R A+ Q + + A QA+ A + E K K A K A
Sbjct: 1044 EELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGA 1103
Query: 2638 EAQDTATRVQSQLQAMQENVERWQG-QYEGLRGQDLGQAVLDAGHSVSTLEKTLPQL 2693
Q T + E ++R + + E LRG QA++ ++ LEK + Q+
Sbjct: 1104 RIQSVKTEAEELFGETMEMMDRMKDMELELLRG---SQAIMLRSADLTGLEKRVEQI 1157
Score = 171 bits (434), Expect = 9e-42
Identities = 101/300 (33%), Positives = 132/300 (44%), Gaps = 45/300 (15%)
Query: 605 CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTC---------DPRGALDQLCG 645
C+CQ AGP+C+RC P Y+ P CQ C C DP
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 646 AGGLC-RCRPGYTGTACQECS--------PGFHGFPSCVPCHCSAEGSLHAA-CDPRSGQ 695
GG+C CR G C+ C PG +C+ C C +G++ A CDP +GQ
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 696 CSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV----DPALPEAQVPCMCRAHVE 751
C C+ V G RCD C PG Y CH + D E C+C +V
Sbjct: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
Query: 752 GPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS- 810
GP CD+C P W L+ +GC C+CD +L +C TGQC C+ G C++
Sbjct: 459 GPKCDQCAPYHWKLASG--QGCEPCACDPHNSLS--PQCNQFTGQCPCREGFGGLMCSAA 514
Query: 811 ----CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
C D +G D A GCR+C CD G G C+ +G C CRP GP C + R +
Sbjct: 515 AIRQCPDRTYG-DVAT--GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Score = 166 bits (420), Expect = 4e-40
Identities = 109/321 (33%), Positives = 140/321 (43%), Gaps = 56/321 (17%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C+ N +G C+ CA + P P+ D E CDC+ C
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPW---RPAEGQDAHE-------CQRCDCNG---HSETC 325
Query: 507 RKDPRV---------GRC-LCKPNFQGTHCELCAPGFYG---PG------CQPCQCSSPG 547
DP V G C C+ + +G +CE C ++ PG C C+C G
Sbjct: 326 HFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDG 385
Query: 548 -VADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGCSPAGTLPE-GCD 600
V CDP TGQC C+ +G CD C PG+ C C C+ G+ + CD
Sbjct: 386 AVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCD 445
Query: 601 E-AGRCLCQPEFAGPHCDRCRPGYH----GFPNCQACTCDPRGALDQLCGA-GGLCRCRP 654
E +GRCLC P GP CD+C P YH C+ C CDP +L C G C CR
Sbjct: 446 EESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 655 GYTGTAC-----QECSPGFHG--FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
G+ G C ++C +G C C C G+ CD SG+C CRP +TG RC
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 708 DTCVPGAYN-FPYCEAGSCHP 727
D C G N +P C A CHP
Sbjct: 565 DQCQRGYCNRYPVCVA--CHP 583
Score = 133 bits (335), Expect = 3e-30
Identities = 93/300 (31%), Positives = 118/300 (39%), Gaps = 49/300 (16%)
Query: 515 CLCKPNFQGTHCELCAPGF----YGPG-------CQPCQCSS--------PGVADDRCDP 555
C+C+ N G +CE CAP + + P CQ C C+ P V
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 556 DTGQC-RCRVGFEGATCDRCAPGYFHF--------PLCQLCGCSPAGTLPEG-CDEA-GR 604
G C CR EG C+RC YF C C C P G +P CD G+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 605 CLCQPEFAGPHCDRCRPGYHGFP-----NCQACTCDPRGAL-DQLCGA-GGLCRCRPGYT 657
C+C+ G CD C+PG+ G C C C+ G+ D C G C C P
Sbjct: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
Query: 658 GTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT----- 709
G C +C+P S C PC C SL C+ +GQC CR GL C
Sbjct: 459 GPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQ 518
Query: 710 CVPGAYN--FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSP 767
C Y C A C G P +A C+CR + GP CD+C+ G+ P
Sbjct: 519 CPDRTYGDVATGCRACDCDFRGTE--GPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYP 576
Score = 127 bits (318), Expect = 3e-28
Identities = 70/195 (35%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 1438 CGCHEVGAT-GPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP-----NCRPCDC---GA 1488
C C GA G C+P GQC C HV G C C G+ G C CDC G+
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1489 RL---CDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545
R CDE +G+C+C P + P C C P + GCE C C P C+
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDP---HNSLSPQCNQ 495
Query: 1546 DSGQCKCRPNVTGRRCDT-----CSPGFHG--YPRCRPCDCHEAGTAPGVCDPLTGQCYC 1598
+GQC CR G C C +G CR CDC GT CD +G+C C
Sbjct: 496 FTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLC 555
Query: 1599 KENVQGPKCDQCSLG 1613
+ + GP+CDQC G
Sbjct: 556 RPGLTGPRCDQCQRG 570
Score = 114 bits (285), Expect = 2e-24
Identities = 83/271 (30%), Positives = 105/271 (38%), Gaps = 54/271 (19%)
Query: 603 GRCLCQPEFAGPHCDRC--RPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
G C C H DRC +PG P+ D +C C+ G
Sbjct: 248 GSCFCHG-----HADRCAPKPGASAGPSTAVQVHD-------------VCVCQHNTAGPN 289
Query: 661 CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC 720
C+ C+P ++ P AEG C +C C D V A Y
Sbjct: 290 CERCAPFYNNRP-----WRPAEGQDAHECQ----RCDCNGHSETCHFDPAVFAASQGAY- 339
Query: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL---SPSNPEGCTRCS 777
G C CR H EG +C+RC+ ++ S E C C
Sbjct: 340 -GGVCDN------------------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCE 380
Query: 778 CDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI-GGA 836
CD G + G A C P TGQC CK HV G+ C CK GF GL A+ GC C C+I G
Sbjct: 381 CDPDGAVPG-APCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSR 439
Query: 837 LGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
C+ +G C C PN GP C + A H+
Sbjct: 440 RDMPCDEESGRCLCLPNVVGPKCDQCAPYHW 470
Score = 104 bits (260), Expect = 1e-21
Identities = 67/199 (33%), Positives = 83/199 (41%), Gaps = 36/199 (18%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRP-CDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513
G C CH H RCA +P G ++ C+C T P+C C
Sbjct: 248 GSCFCHGHA-----DRCAP--------KPGASAGPSTAVQVHDVCVCQHNTAGPNCERCA 294
Query: 1514 P--QTFGCHPLVG-----CEECNCSGPGIQELTDPTCDTDS-----GQC-KCRPNVTGRR 1560
P P G C+ C+C+G DP S G C CR + G+
Sbjct: 295 PFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKN 354
Query: 1561 CDTCS--------PGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKCDQCS 1611
C+ C PG C C+C G PG CDP+TGQC CKE+VQG +CD C
Sbjct: 355 CERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
Query: 1612 LGTFSLDAANPKGCTRCFC 1630
G L ANP+GC RC C
Sbjct: 415 PGFTGLTYANPQGCHRCDC 433
Score = 36.2 bits (82), Expect = 0.62
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 1569 HGYP-RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKG--- 1624
HG+ RC P AG P + C C+ N GP C++C+ + +G
Sbjct: 253 HGHADRCAPKPGASAG--PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
Query: 1625 --CTRCFCFGATERC 1637
C RC C G +E C
Sbjct: 311 HECQRCDCNGHSETC 325
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 323 bits (829), Expect = 1e-87
Identities = 215/648 (33%), Positives = 304/648 (46%), Gaps = 105/648 (16%)
Query: 21 PLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGAR--IAASATCGEEAPARGSPRPTE 78
P L+ AL G A++ G + +PP +L G + AS+TCG P
Sbjct: 3 PFFLLCFALPGLLHAQQACSRG-ACYPPVGDLLVGRTRFLRASSTCGLTKP--------- 52
Query: 79 DLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASN-------AIDGTERWWQSP 131
+ YC T G++ C +S + H + + G RWWQS
Sbjct: 53 ETYC--------------TQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQ 98
Query: 132 PLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASS 191
+ N V++ LDL + F + V+++F P P ++ERS DFG+T++ +Q+ A+
Sbjct: 99 N-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQYLAA- 151
Query: 192 KRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIV----VSLVNGRPGAMNFSYS 247
DC F R C + R NG V + LV+G P S
Sbjct: 152 --DCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMDLVSGIPATQ----S 205
Query: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHAD 307
++E + TN+R+ F R L + + P+ YY++ + + G C CHGHAD
Sbjct: 206 QKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGHAD 257
Query: 308 ACDAKD-----PTDPFRLQ--CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
C K P+ ++ C CQHNT G C+RC P +N +PW+PA A+ECQ C+
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
C GH+ C++DP V ASQ G Y GGVC +C+ HT G NCERC ++R+
Sbjct: 318 CNGHSETCHFDPAV--FAASQ---GAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
Query: 421 DSPHVCRRCNCESD--FTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSS 478
C C C+ D C+ +TG+C C+ + GERCD+C GFTG Y P
Sbjct: 371 SIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL--TYANPQGC 428
Query: 479 NDTREQVLPAGQIVNCDCSAAGTQGN-ACRKDPRVGRCLCKPNFQGTHCELCAPGFY--- 534
+ CDC+ G++ + C D GRCLC PN G C+ CAP +
Sbjct: 429 H-------------RCDCNILGSRRDMPC--DEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
Query: 535 -GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCA----PGYFHFPL---CQL 586
G GC+PC C +C+ TGQC CR GF G C A P + + C+
Sbjct: 474 SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA 533
Query: 587 CGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGY-HGFPNCQAC 632
C C GT GCD+A GRCLC+P GP CD+C+ GY + +P C AC
Sbjct: 534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Score = 216 bits (550), Expect = 3e-55
Identities = 256/957 (26%), Positives = 363/957 (37%), Gaps = 176/957 (18%)
Query: 1864 CQCHGHSDRCLPGSG-------------VCVDCQHNTEGAHCERCQAGFVSSRD------ 1904
C CHGH+DRC P G VCV CQHNT G +CERC A F ++R
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERC-APFYNNRPWRPAEG 307
Query: 1905 DPSAPCVSCPCPLSVPSNNFAEGC--------VLRG--GRTQCLCKPGYAGASCERCAPG 1954
+ C C C N +E C +G G C+ G +CERC
Sbjct: 308 QDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 1955 FFGNP---LVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+F N + +C C+C +G + + CDP+TG C C H G RC++C PGF
Sbjct: 362 YFRNRRPGASIQETCISCECDPDGA--VPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
Query: 2012 GNALL-PGNCTRCDCTPCGTEA---CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGC 2067
G P C RCDC G+ CD SG CLC V G +CD+C H+ GC
Sbjct: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGC 478
Query: 2068 RPCACGPAAEGS-ECHPQSGQCHCRPGTMGPQC-----RECAPGYWGLPEQGCRRCQC-- 2119
PCAC P S +C+ +GQC CR G G C R+C +G GCR C C
Sbjct: 479 EPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
Query: 2120 ---PGGRCDPHTGRCNCPPGLSGERCDTCSQQH--QVPVPGGPVGHSIHCEVCDHCVVLL 2174
G CD +GRC C PGL+G RCD C + + + PV C C C
Sbjct: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPV----------CVACHPCFQTY 588
Query: 2175 LDDLE----RAGALLPAIHEQLRGINASSMAWA-RLHRLNASIADLQSQLRSPLGPRHET 2229
DL R G L A G A R+ + I +++ L SP E
Sbjct: 589 DADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEV 648
Query: 2230 AQ---------------QLEV-LEQQSTSLGQDARRLGGQAVG-------TRDQ------ 2260
AQ QL++ LE+++ SL +D L G R+Q
Sbjct: 649 AQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISS 708
Query: 2261 ------------ASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPS 2308
A + A + + LL +R R L+ Q G G +P
Sbjct: 709 ADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAG--GGGGTGSPK 766
Query: 2309 GEQLLRTLAEVERLLWEM-----RARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEEN 2363
L ++ + L +R + + EL A L
Sbjct: 767 LVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAG 826
Query: 2364 QA--LATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSR 2421
A +A Q ++L A L R+ + A ++ A ++ S Q + + ++
Sbjct: 827 GAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEES---ASQIQSSAQRLETQVSASRSQMEE 883
Query: 2422 DNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSK 2481
D + + RD L ++ + E + L D A +LQ+M
Sbjct: 884 DVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA--TVLQKMNEI------ 935
Query: 2482 LRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQ 2541
+A A +L + L LS D+ + R Q EA A SR ED G
Sbjct: 936 -------QAIAARLPNVDLVLSQTKQDIARARRLQ--AEAEEARSRAHAVEGQVEDVVGN 986
Query: 2542 ------ALQQADHTWATVVR-----QGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAAL 2590
ALQ+A T R Q V QQ+L + L +M ++ LG W +
Sbjct: 987 LRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQ---LGDFWTRM 1043
Query: 2591 QGARTQLRDVRAKKDQLEAHIQAA--QAMLAMDTDETSK-KIAHAK----------AVAA 2637
+ R Q R A+ Q + + A QA+ A + E K K A K A
Sbjct: 1044 EELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGA 1103
Query: 2638 EAQDTATRVQSQLQAMQENVERWQG-QYEGLRGQDLGQAVLDAGHSVSTLEKTLPQL 2693
Q T + E ++R + + E LRG QA++ ++ LEK + Q+
Sbjct: 1104 RIQSVKTEAEELFGETMEMMDRMKDMELELLRG---SQAIMLRSADLTGLEKRVEQI 1157
Score = 171 bits (434), Expect = 9e-42
Identities = 101/300 (33%), Positives = 132/300 (44%), Gaps = 45/300 (15%)
Query: 605 CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTC---------DPRGALDQLCG 645
C+CQ AGP+C+RC P Y+ P CQ C C DP
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 646 AGGLC-RCRPGYTGTACQECS--------PGFHGFPSCVPCHCSAEGSLHAA-CDPRSGQ 695
GG+C CR G C+ C PG +C+ C C +G++ A CDP +GQ
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 696 CSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV----DPALPEAQVPCMCRAHVE 751
C C+ V G RCD C PG Y CH + D E C+C +V
Sbjct: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
Query: 752 GPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS- 810
GP CD+C P W L+ +GC C+CD +L +C TGQC C+ G C++
Sbjct: 459 GPKCDQCAPYHWKLASG--QGCEPCACDPHNSLS--PQCNQFTGQCPCREGFGGLMCSAA 514
Query: 811 ----CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
C D +G D A GCR+C CD G G C+ +G C CRP GP C + R +
Sbjct: 515 AIRQCPDRTYG-DVAT--GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Score = 166 bits (420), Expect = 4e-40
Identities = 109/321 (33%), Positives = 140/321 (43%), Gaps = 56/321 (17%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C+ N +G C+ CA + P P+ D E CDC+ C
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPW---RPAEGQDAHE-------CQRCDCNG---HSETC 325
Query: 507 RKDPRV---------GRC-LCKPNFQGTHCELCAPGFYG---PG------CQPCQCSSPG 547
DP V G C C+ + +G +CE C ++ PG C C+C G
Sbjct: 326 HFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDG 385
Query: 548 -VADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGCSPAGTLPE-GCD 600
V CDP TGQC C+ +G CD C PG+ C C C+ G+ + CD
Sbjct: 386 AVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCD 445
Query: 601 E-AGRCLCQPEFAGPHCDRCRPGYH----GFPNCQACTCDPRGALDQLCGA-GGLCRCRP 654
E +GRCLC P GP CD+C P YH C+ C CDP +L C G C CR
Sbjct: 446 EESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 655 GYTGTAC-----QECSPGFHG--FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
G+ G C ++C +G C C C G+ CD SG+C CRP +TG RC
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 708 DTCVPGAYN-FPYCEAGSCHP 727
D C G N +P C A CHP
Sbjct: 565 DQCQRGYCNRYPVCVA--CHP 583
Score = 133 bits (335), Expect = 3e-30
Identities = 93/300 (31%), Positives = 118/300 (39%), Gaps = 49/300 (16%)
Query: 515 CLCKPNFQGTHCELCAPGF----YGPG-------CQPCQCSS--------PGVADDRCDP 555
C+C+ N G +CE CAP + + P CQ C C+ P V
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 556 DTGQC-RCRVGFEGATCDRCAPGYFHF--------PLCQLCGCSPAGTLPEG-CDEA-GR 604
G C CR EG C+RC YF C C C P G +P CD G+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 605 CLCQPEFAGPHCDRCRPGYHGFP-----NCQACTCDPRGAL-DQLCGA-GGLCRCRPGYT 657
C+C+ G CD C+PG+ G C C C+ G+ D C G C C P
Sbjct: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
Query: 658 GTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT----- 709
G C +C+P S C PC C SL C+ +GQC CR GL C
Sbjct: 459 GPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQ 518
Query: 710 CVPGAYN--FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSP 767
C Y C A C G P +A C+CR + GP CD+C+ G+ P
Sbjct: 519 CPDRTYGDVATGCRACDCDFRGTE--GPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYP 576
Score = 127 bits (318), Expect = 3e-28
Identities = 70/195 (35%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 1438 CGCHEVGAT-GPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP-----NCRPCDC---GA 1488
C C GA G C+P GQC C HV G C C G+ G C CDC G+
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1489 RL---CDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545
R CDE +G+C+C P + P C C P + GCE C C P C+
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDP---HNSLSPQCNQ 495
Query: 1546 DSGQCKCRPNVTGRRCDT-----CSPGFHG--YPRCRPCDCHEAGTAPGVCDPLTGQCYC 1598
+GQC CR G C C +G CR CDC GT CD +G+C C
Sbjct: 496 FTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLC 555
Query: 1599 KENVQGPKCDQCSLG 1613
+ + GP+CDQC G
Sbjct: 556 RPGLTGPRCDQCQRG 570
Score = 114 bits (285), Expect = 2e-24
Identities = 83/271 (30%), Positives = 105/271 (38%), Gaps = 54/271 (19%)
Query: 603 GRCLCQPEFAGPHCDRC--RPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
G C C H DRC +PG P+ D +C C+ G
Sbjct: 248 GSCFCHG-----HADRCAPKPGASAGPSTAVQVHD-------------VCVCQHNTAGPN 289
Query: 661 CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC 720
C+ C+P ++ P AEG C +C C D V A Y
Sbjct: 290 CERCAPFYNNRP-----WRPAEGQDAHECQ----RCDCNGHSETCHFDPAVFAASQGAY- 339
Query: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL---SPSNPEGCTRCS 777
G C CR H EG +C+RC+ ++ S E C C
Sbjct: 340 -GGVCDN------------------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCE 380
Query: 778 CDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI-GGA 836
CD G + G A C P TGQC CK HV G+ C CK GF GL A+ GC C C+I G
Sbjct: 381 CDPDGAVPG-APCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSR 439
Query: 837 LGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
C+ +G C C PN GP C + A H+
Sbjct: 440 RDMPCDEESGRCLCLPNVVGPKCDQCAPYHW 470
Score = 104 bits (260), Expect = 1e-21
Identities = 67/199 (33%), Positives = 83/199 (41%), Gaps = 36/199 (18%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRP-CDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513
G C CH H RCA +P G ++ C+C T P+C C
Sbjct: 248 GSCFCHGHA-----DRCAP--------KPGASAGPSTAVQVHDVCVCQHNTAGPNCERCA 294
Query: 1514 P--QTFGCHPLVG-----CEECNCSGPGIQELTDPTCDTDS-----GQC-KCRPNVTGRR 1560
P P G C+ C+C+G DP S G C CR + G+
Sbjct: 295 PFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKN 354
Query: 1561 CDTCS--------PGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKCDQCS 1611
C+ C PG C C+C G PG CDP+TGQC CKE+VQG +CD C
Sbjct: 355 CERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
Query: 1612 LGTFSLDAANPKGCTRCFC 1630
G L ANP+GC RC C
Sbjct: 415 PGFTGLTYANPQGCHRCDC 433
Score = 36.2 bits (82), Expect = 0.62
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 1569 HGYP-RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKG--- 1624
HG+ RC P AG P + C C+ N GP C++C+ + +G
Sbjct: 253 HGHADRCAPKPGASAG--PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
Query: 1625 --CTRCFCFGATERC 1637
C RC C G +E C
Sbjct: 311 HECQRCDCNGHSETC 325
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 323 bits (829), Expect = 1e-87
Identities = 215/648 (33%), Positives = 304/648 (46%), Gaps = 105/648 (16%)
Query: 21 PLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGAR--IAASATCGEEAPARGSPRPTE 78
P L+ AL G A++ G + +PP +L G + AS+TCG P
Sbjct: 3 PFFLLCFALPGLLHAQQACSRG-ACYPPVGDLLVGRTRFLRASSTCGLTKP--------- 52
Query: 79 DLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASN-------AIDGTERWWQSP 131
+ YC T G++ C +S + H + + G RWWQS
Sbjct: 53 ETYC--------------TQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQ 98
Query: 132 PLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASS 191
+ N V++ LDL + F + V+++F P P ++ERS DFG+T++ +Q+ A+
Sbjct: 99 N-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQYLAA- 151
Query: 192 KRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIV----VSLVNGRPGAMNFSYS 247
DC F R C + R NG V + LV+G P S
Sbjct: 152 --DCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMDLVSGIPATQ----S 205
Query: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHAD 307
++E + TN+R+ F R L + + P+ YY++ + + G C CHGHAD
Sbjct: 206 QKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGHAD 257
Query: 308 ACDAKD-----PTDPFRLQ--CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
C K P+ ++ C CQHNT G C+RC P +N +PW+PA A+ECQ C+
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
C GH+ C++DP V ASQ G Y GGVC +C+ HT G NCERC ++R+
Sbjct: 318 CNGHSETCHFDPAV--FAASQ---GAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
Query: 421 DSPHVCRRCNCESD--FTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSS 478
C C C+ D C+ +TG+C C+ + GERCD+C GFTG Y P
Sbjct: 371 SIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL--TYANPQGC 428
Query: 479 NDTREQVLPAGQIVNCDCSAAGTQGN-ACRKDPRVGRCLCKPNFQGTHCELCAPGFY--- 534
+ CDC+ G++ + C D GRCLC PN G C+ CAP +
Sbjct: 429 H-------------RCDCNILGSRRDMPC--DEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
Query: 535 -GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCA----PGYFHFPL---CQL 586
G GC+PC C +C+ TGQC CR GF G C A P + + C+
Sbjct: 474 SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA 533
Query: 587 CGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGY-HGFPNCQAC 632
C C GT GCD+A GRCLC+P GP CD+C+ GY + +P C AC
Sbjct: 534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Score = 216 bits (550), Expect = 3e-55
Identities = 256/957 (26%), Positives = 363/957 (37%), Gaps = 176/957 (18%)
Query: 1864 CQCHGHSDRCLPGSG-------------VCVDCQHNTEGAHCERCQAGFVSSRD------ 1904
C CHGH+DRC P G VCV CQHNT G +CERC A F ++R
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERC-APFYNNRPWRPAEG 307
Query: 1905 DPSAPCVSCPCPLSVPSNNFAEGC--------VLRG--GRTQCLCKPGYAGASCERCAPG 1954
+ C C C N +E C +G G C+ G +CERC
Sbjct: 308 QDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 1955 FFGNP---LVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+F N + +C C+C +G + + CDP+TG C C H G RC++C PGF
Sbjct: 362 YFRNRRPGASIQETCISCECDPDGA--VPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
Query: 2012 GNALL-PGNCTRCDCTPCGTEA---CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGC 2067
G P C RCDC G+ CD SG CLC V G +CD+C H+ GC
Sbjct: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGC 478
Query: 2068 RPCACGPAAEGS-ECHPQSGQCHCRPGTMGPQC-----RECAPGYWGLPEQGCRRCQC-- 2119
PCAC P S +C+ +GQC CR G G C R+C +G GCR C C
Sbjct: 479 EPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
Query: 2120 ---PGGRCDPHTGRCNCPPGLSGERCDTCSQQH--QVPVPGGPVGHSIHCEVCDHCVVLL 2174
G CD +GRC C PGL+G RCD C + + + PV C C C
Sbjct: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPV----------CVACHPCFQTY 588
Query: 2175 LDDLE----RAGALLPAIHEQLRGINASSMAWA-RLHRLNASIADLQSQLRSPLGPRHET 2229
DL R G L A G A R+ + I +++ L SP E
Sbjct: 589 DADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEV 648
Query: 2230 AQ---------------QLEV-LEQQSTSLGQDARRLGGQAVG-------TRDQ------ 2260
AQ QL++ LE+++ SL +D L G R+Q
Sbjct: 649 AQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISS 708
Query: 2261 ------------ASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPS 2308
A + A + + LL +R R L+ Q G G +P
Sbjct: 709 ADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAG--GGGGTGSPK 766
Query: 2309 GEQLLRTLAEVERLLWEM-----RARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEEN 2363
L ++ + L +R + + EL A L
Sbjct: 767 LVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAG 826
Query: 2364 QA--LATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSR 2421
A +A Q ++L A L R+ + A ++ A ++ S Q + + ++
Sbjct: 827 GAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEES---ASQIQSSAQRLETQVSASRSQMEE 883
Query: 2422 DNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSK 2481
D + + RD L ++ + E + L D A +LQ+M
Sbjct: 884 DVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA--TVLQKMNEI------ 935
Query: 2482 LRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQ 2541
+A A +L + L LS D+ + R Q EA A SR ED G
Sbjct: 936 -------QAIAARLPNVDLVLSQTKQDIARARRLQ--AEAEEARSRAHAVEGQVEDVVGN 986
Query: 2542 ------ALQQADHTWATVVR-----QGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAAL 2590
ALQ+A T R Q V QQ+L + L +M ++ LG W +
Sbjct: 987 LRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQ---LGDFWTRM 1043
Query: 2591 QGARTQLRDVRAKKDQLEAHIQAA--QAMLAMDTDETSK-KIAHAK----------AVAA 2637
+ R Q R A+ Q + + A QA+ A + E K K A K A
Sbjct: 1044 EELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGA 1103
Query: 2638 EAQDTATRVQSQLQAMQENVERWQG-QYEGLRGQDLGQAVLDAGHSVSTLEKTLPQL 2693
Q T + E ++R + + E LRG QA++ ++ LEK + Q+
Sbjct: 1104 RIQSVKTEAEELFGETMEMMDRMKDMELELLRG---SQAIMLRSADLTGLEKRVEQI 1157
Score = 171 bits (434), Expect = 9e-42
Identities = 101/300 (33%), Positives = 132/300 (44%), Gaps = 45/300 (15%)
Query: 605 CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTC---------DPRGALDQLCG 645
C+CQ AGP+C+RC P Y+ P CQ C C DP
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 646 AGGLC-RCRPGYTGTACQECS--------PGFHGFPSCVPCHCSAEGSLHAA-CDPRSGQ 695
GG+C CR G C+ C PG +C+ C C +G++ A CDP +GQ
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 696 CSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV----DPALPEAQVPCMCRAHVE 751
C C+ V G RCD C PG Y CH + D E C+C +V
Sbjct: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
Query: 752 GPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS- 810
GP CD+C P W L+ +GC C+CD +L +C TGQC C+ G C++
Sbjct: 459 GPKCDQCAPYHWKLASG--QGCEPCACDPHNSLS--PQCNQFTGQCPCREGFGGLMCSAA 514
Query: 811 ----CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
C D +G D A GCR+C CD G G C+ +G C CRP GP C + R +
Sbjct: 515 AIRQCPDRTYG-DVAT--GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
Score = 166 bits (420), Expect = 4e-40
Identities = 109/321 (33%), Positives = 140/321 (43%), Gaps = 56/321 (17%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C C+ N +G C+ CA + P P+ D E CDC+ C
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPW---RPAEGQDAHE-------CQRCDCNG---HSETC 325
Query: 507 RKDPRV---------GRC-LCKPNFQGTHCELCAPGFYG---PG------CQPCQCSSPG 547
DP V G C C+ + +G +CE C ++ PG C C+C G
Sbjct: 326 HFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDG 385
Query: 548 -VADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGCSPAGTLPE-GCD 600
V CDP TGQC C+ +G CD C PG+ C C C+ G+ + CD
Sbjct: 386 AVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCD 445
Query: 601 E-AGRCLCQPEFAGPHCDRCRPGYH----GFPNCQACTCDPRGALDQLCGA-GGLCRCRP 654
E +GRCLC P GP CD+C P YH C+ C CDP +L C G C CR
Sbjct: 446 EESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCRE 504
Query: 655 GYTGTAC-----QECSPGFHG--FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
G+ G C ++C +G C C C G+ CD SG+C CRP +TG RC
Sbjct: 505 GFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 708 DTCVPGAYN-FPYCEAGSCHP 727
D C G N +P C A CHP
Sbjct: 565 DQCQRGYCNRYPVCVA--CHP 583
Score = 133 bits (335), Expect = 3e-30
Identities = 93/300 (31%), Positives = 118/300 (39%), Gaps = 49/300 (16%)
Query: 515 CLCKPNFQGTHCELCAPGF----YGPG-------CQPCQCSS--------PGVADDRCDP 555
C+C+ N G +CE CAP + + P CQ C C+ P V
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 556 DTGQC-RCRVGFEGATCDRCAPGYFHF--------PLCQLCGCSPAGTLPEG-CDEA-GR 604
G C CR EG C+RC YF C C C P G +P CD G+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 605 CLCQPEFAGPHCDRCRPGYHGFP-----NCQACTCDPRGAL-DQLCGA-GGLCRCRPGYT 657
C+C+ G CD C+PG+ G C C C+ G+ D C G C C P
Sbjct: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
Query: 658 GTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT----- 709
G C +C+P S C PC C SL C+ +GQC CR GL C
Sbjct: 459 GPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQ 518
Query: 710 CVPGAYN--FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSP 767
C Y C A C G P +A C+CR + GP CD+C+ G+ P
Sbjct: 519 CPDRTYGDVATGCRACDCDFRGTE--GPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYP 576
Score = 127 bits (318), Expect = 3e-28
Identities = 70/195 (35%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 1438 CGCHEVGAT-GPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP-----NCRPCDC---GA 1488
C C GA G C+P GQC C HV G C C G+ G C CDC G+
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 1489 RL---CDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545
R CDE +G+C+C P + P C C P + GCE C C P C+
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDP---HNSLSPQCNQ 495
Query: 1546 DSGQCKCRPNVTGRRCDT-----CSPGFHG--YPRCRPCDCHEAGTAPGVCDPLTGQCYC 1598
+GQC CR G C C +G CR CDC GT CD +G+C C
Sbjct: 496 FTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLC 555
Query: 1599 KENVQGPKCDQCSLG 1613
+ + GP+CDQC G
Sbjct: 556 RPGLTGPRCDQCQRG 570
Score = 114 bits (285), Expect = 2e-24
Identities = 83/271 (30%), Positives = 105/271 (38%), Gaps = 54/271 (19%)
Query: 603 GRCLCQPEFAGPHCDRC--RPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
G C C H DRC +PG P+ D +C C+ G
Sbjct: 248 GSCFCHG-----HADRCAPKPGASAGPSTAVQVHD-------------VCVCQHNTAGPN 289
Query: 661 CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC 720
C+ C+P ++ P AEG C +C C D V A Y
Sbjct: 290 CERCAPFYNNRP-----WRPAEGQDAHECQ----RCDCNGHSETCHFDPAVFAASQGAY- 339
Query: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL---SPSNPEGCTRCS 777
G C CR H EG +C+RC+ ++ S E C C
Sbjct: 340 -GGVCDN------------------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCE 380
Query: 778 CDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI-GGA 836
CD G + G A C P TGQC CK HV G+ C CK GF GL A+ GC C C+I G
Sbjct: 381 CDPDGAVPG-APCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSR 439
Query: 837 LGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
C+ +G C C PN GP C + A H+
Sbjct: 440 RDMPCDEESGRCLCLPNVVGPKCDQCAPYHW 470
Score = 104 bits (260), Expect = 1e-21
Identities = 67/199 (33%), Positives = 83/199 (41%), Gaps = 36/199 (18%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRP-CDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513
G C CH H RCA +P G ++ C+C T P+C C
Sbjct: 248 GSCFCHGHA-----DRCAP--------KPGASAGPSTAVQVHDVCVCQHNTAGPNCERCA 294
Query: 1514 P--QTFGCHPLVG-----CEECNCSGPGIQELTDPTCDTDS-----GQC-KCRPNVTGRR 1560
P P G C+ C+C+G DP S G C CR + G+
Sbjct: 295 PFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKN 354
Query: 1561 CDTCS--------PGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKCDQCS 1611
C+ C PG C C+C G PG CDP+TGQC CKE+VQG +CD C
Sbjct: 355 CERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
Query: 1612 LGTFSLDAANPKGCTRCFC 1630
G L ANP+GC RC C
Sbjct: 415 PGFTGLTYANPQGCHRCDC 433
Score = 36.2 bits (82), Expect = 0.62
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 1569 HGYP-RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKG--- 1624
HG+ RC P AG P + C C+ N GP C++C+ + +G
Sbjct: 253 HGHADRCAPKPGASAG--PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
Query: 1625 --CTRCFCFGATERC 1637
C RC C G +E C
Sbjct: 311 HECQRCDCNGHSETC 325
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 293 bits (751), Expect = 2e-78
Identities = 201/597 (33%), Positives = 271/597 (45%), Gaps = 78/597 (13%)
Query: 1509 CLLCQPQTFGCH------------PLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNV 1556
CL C T G H C CNC+ G CD +SG+C C+P V
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGS---LSARCD-NSGRCSCKPGV 108
Query: 1557 TGRRCDTCSPGFHGYPRC----------RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
TG RCD C PGFH CDC AG A G CD G+C CK V G +
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGER 165
Query: 1607 CDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSS------YTRQEFVDMEGWVLLSTDR 1660
CD+C G ++LD NP+GCT+CFC+G + CRSS+ T D++GW +
Sbjct: 166 CDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAV---- 221
Query: 1661 QVVPHERQPGTEMLRADLRHVPE-AVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSE 1719
+R L+ RH + + +Y+ AP +LG++ SYG +L ++
Sbjct: 222 -----QRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD---- 272
Query: 1720 TQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRN--- 1776
R D S DV+L+G + IT P P + G + + N
Sbjct: 273 -YRVDRGGRHPSAHDVILEGAGLRIT--APLMPLGKTLPCGLTKTYTFRLNEHPSNNWSP 329
Query: 1777 TVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPAS 1836
+S E +L +L L+IRA + + S+ ++ V L A P GA A VE C+CP
Sbjct: 330 QLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARPV-SGAPAPWVEQCICPVG 387
Query: 1837 YRGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERC 1895
Y+G CQ+CA G+ RD L G C+PC C G C P +G C N + C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECADC 445
Query: 1896 QAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQC-LCKPGYAGASCERCAPG 1954
GF + DP + C CPC N F+ + C C PG GA CE CA G
Sbjct: 446 PIGFYNDPHDPRS-CKPCPC-----HNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
Query: 1955 FFGNPLVLGS---SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+FG+P CQPC C+ N DP+ +CD LTG C C+ +T G C+ C G++
Sbjct: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPS-ASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 2012 GNALLPG---NCTRCDCTPCGTEACDPHS-GHCLCKAGVTGRRCDRCQEGHFGFDGC 2064
G+ L P C C+C P G+E S G C+CK G G C+ G F C
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG---PNCEHGAFSCPAC 612
Score = 125 bits (313), Expect = 1e-27
Identities = 88/273 (32%), Positives = 113/273 (41%), Gaps = 55/273 (20%)
Query: 393 CIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPN 452
CI C G C+ C G Y+ + L C CNC+ G C+ TG CY
Sbjct: 382 CI-CPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYSGDE 436
Query: 453 FSGERCDVCAEGFTGFP----SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK 508
C C GF P SC P P N V+P + V C+
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNN------------ 483
Query: 509 DPRVGRCLCKPNFQGTHCELCAPGFYGPG---------CQPCQCSS--PGVADDRCDPDT 557
C P G CELCA G++G CQPCQC++ A CD T
Sbjct: 484 --------CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLT 535
Query: 558 GQC-RCRVGFEGATCDRCAPGYFHFPL-------CQLCGCSPAGTLPEGCDEAGRCLCQP 609
G+C +C G CD+C GYF PL C+ C C+P G+ P GC G C+C+P
Sbjct: 536 GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKP 595
Query: 610 EFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQ 642
F GP+C+ HG +C AC + +DQ
Sbjct: 596 GFGGPNCE------HGAFSCPACYNQVKIQMDQ 622
Score = 115 bits (287), Expect = 1e-24
Identities = 64/173 (36%), Positives = 88/173 (50%), Gaps = 33/173 (19%)
Query: 630 QACTCDPRGA-------LDQLCGAGGLC-RCRPGYTGTACQECSPGFHGFPS---CVPCH 678
+ C C+ + L + G G C C G C++C GF+ C+PC+
Sbjct: 26 EVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
Query: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAG------------SCH 726
C+++GSL A CD SG+CSC+P VTG RCD C+PG + +AG C
Sbjct: 86 CNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLT--DAGCTQDQRLLDSKCDCD 142
Query: 727 PAGLA-PVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
PAG+A P D C+C+ V G CDRC+ G++ L NPEGCT+C C
Sbjct: 143 PAGIAGPCDAGR------CVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 114 bits (286), Expect = 1e-24
Identities = 79/260 (30%), Positives = 106/260 (40%), Gaps = 54/260 (20%)
Query: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA 505
+C C + G+ C CA G+ ++ P G + C+C G A
Sbjct: 381 QCICPVGYKGQFCQDCASGY-------------KRDSARLGPFGTCIPCNCQGGG----A 423
Query: 506 CRKDPRVGRCLCKPNFQGTHCELCAPGFYGP-----GCQPCQCSSPGVADDRCDPDTGQC 560
C DP G C C C GFY C+PC C + + + C
Sbjct: 424 C--DPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC 481
Query: 561 R-CRVGFEGATCDRCAPGYFHFPL--------CQLCGCS----PAGTLPEGCDE-AGRCL 606
C G GA C+ CA GYF P CQ C C+ P+ + CD GRCL
Sbjct: 482 NNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS--GNCDRLTGRCL 539
Query: 607 -CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAGGLCRCRPGYTG 658
C AG +CD+C+ GY G P C+AC C+P G+ C + G C C+PG+ G
Sbjct: 540 KCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG 599
Query: 659 TACQECSPGFHGFPSCVPCH 678
C+ HG SC C+
Sbjct: 600 PNCE------HGAFSCPACY 613
Score = 111 bits (277), Expect = 2e-23
Identities = 67/178 (37%), Positives = 82/178 (46%), Gaps = 31/178 (17%)
Query: 485 VLPAGQIVN----CDCSAAGTQ----GNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG 535
+LPA + + CDC+ Q R+ RCL C N G HCE C GFY
Sbjct: 15 LLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR 74
Query: 536 ----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFP--------- 582
C PC C+S G RCD ++G+C C+ G GA CDRC PG+
Sbjct: 75 HRERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQR 133
Query: 583 -LCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGF-----PNCQACTC 634
L C C PAG + CD AGRC+C+P G CDRCR GY+ C C C
Sbjct: 134 LLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 110 bits (276), Expect = 2e-23
Identities = 73/232 (31%), Positives = 94/232 (40%), Gaps = 25/232 (10%)
Query: 650 CRCRPGYTGTACQECSPGFHG-------FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRV 702
C C GY G CQ+C+ G+ F +C+PC+C G ACDP +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCYSGDEN 437
Query: 703 TGLRCDTCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRC 758
+ C C G YN P+ C+ CH V P E V C V G C+ C
Sbjct: 438 PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEV-VCNNCPPGVTGARCELC 496
Query: 759 KPGFWGLSPSNPEG----CTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKD 813
G++G P G C C C+ C TG+C C + G C CK
Sbjct: 497 ADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 814 GFFG--LDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPA 863
G+FG L CR+C C+ G+ C G C C+P GP C A
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 105 bits (263), Expect = 6e-22
Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 35/200 (17%)
Query: 350 ANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCL 409
A + + + C+C G + C +D E+ R+ + G C++C +T G++CE+C
Sbjct: 19 ARATSRREVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCEKCK 69
Query: 410 PGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
GFYR C CNC S + D +GRC C+P +G RCD C GF
Sbjct: 70 NGFYRHRERDR-----CLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHML- 123
Query: 470 SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
+ + T++Q L + CDC AG G GRC+CKP G C+ C
Sbjct: 124 ------TDAGCTQDQRLLDSK---CDCDPAGIAGPC-----DAGRCVCKPAVTGERCDRC 169
Query: 530 APGFYG------PGCQPCQC 543
G+Y GC C C
Sbjct: 170 RSGYYNLDGGNPEGCTQCFC 189
Score = 97.4 bits (241), Expect = 2e-19
Identities = 70/240 (29%), Positives = 92/240 (38%), Gaps = 51/240 (21%)
Query: 555 PDTGQCRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCL 606
P QC C VG++G C CA GY F C C C G CD + G C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCY 432
Query: 607 CQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC------------RCRP 654
E C C G++ P+ DPR C G C C P
Sbjct: 433 SGDENPDIECADCPIGFYNDPH------DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPP 486
Query: 655 GYTGTACQECSPGFHGFP--------SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVT 703
G TG C+ C+ G+ G P C PC C + + S CD +G+C C
Sbjct: 487 GVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA 546
Query: 704 GLRCDTCVPGAYNFPY-------CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756
G+ CD C G + P C A +C+P G PV + C+C+ GP+C+
Sbjct: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVG---CRSDGTCVCKPGFGGPNCE 603
Score = 95.9 bits (237), Expect = 7e-19
Identities = 173/759 (22%), Positives = 269/759 (35%), Gaps = 144/759 (18%)
Query: 2000 GPRCEICAPGFYGNA--LLP-GNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQE 2056
G C+ CA G+ ++ L P G C C+C G ACDP +G C C C
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNCQ--GGGACDPDTGDCYSGDENPDIECADCPI 447
Query: 2057 GHFGFD-GCGGCRPCACGPAAEGSECH--PQSGQC---HCRPGTMGPQCRECAPGYWGLP 2110
G + C+PC C G C P++ + +C PG G +C CA GY+G P
Sbjct: 448 GFYNDPHDPRSCKPCPCH---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDP 504
Query: 2111 --EQG----CRRCQC-------PGGRCDPHTGRC-NCPPGLSGERCDTCSQQH------- 2149
E G C+ CQC G CD TGRC C +G CD C +
Sbjct: 505 FGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
Query: 2150 ----------QVPVPGGPVG--------------------HSIHCEVCDHCVVLLLD--- 2176
P+ PVG + C C + V + +D
Sbjct: 565 NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFM 624
Query: 2177 -DLERAGALL-----------------------PAIHEQLRGINASSMAWARLHRLNASI 2212
L+R AL+ A+ + LR S A L A +
Sbjct: 625 QQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKV 684
Query: 2213 ADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATL 2272
++ +S L T +++ L Q + +D RL Q LA +EA+L
Sbjct: 685 RSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRL-------ITQMQLSLAESEASL 737
Query: 2273 GHAKTLLAAIRAVDRTLSELMSQTGHLGLANA-SAPSGEQLLRTLAEVER--LLWEMRAR 2329
G+ + L + L ++ SA + EQL R + + L +A
Sbjct: 738 GNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKAL 797
Query: 2330 DLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTR---DRLAQHEAGLMDLRE 2386
G + + A Q L+ ++ E+ SL ++ ATQ DR QH L+D
Sbjct: 798 HEGVGSGSGSPDGAVVQGLVEKL-EKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVS 856
Query: 2387 ALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHS 2446
L D + + +EEA + KQ+ D+ + T H + R +
Sbjct: 857 RLQGVSDQSFQ-----------VEEAKRIKQK--ADSLSSLVTRH-----MDEFKRTQKN 898
Query: 2447 LDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLR-LVEAAEAHAQQLGQLALNLSSI 2505
L KEE ++L + R Q + + A S+ + + A ++ + NL
Sbjct: 899 LGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREF 958
Query: 2506 ILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQL 2565
L V+ R EA A R+ Q DA+ + QQA+ + RA+
Sbjct: 959 DLQVD-----NRKAEAEEAMKRLSYISQKVSDASDKT-QQAERALGSAAAD--AQRAKNG 1010
Query: 2566 LANSTALEEAMLQEQQRLGL-----------VWAALQGARTQLRDVRAKKDQLEAHIQAA 2614
+ + + QE L L + L ++++R+V + ++ E
Sbjct: 1011 AGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTN 1070
Query: 2615 QAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAM 2653
+ M E K AK QDT + L M
Sbjct: 1071 MDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLM 1109
Score = 94.4 bits (233), Expect = 2e-18
Identities = 69/202 (34%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Query: 1452 PFGGQCPCHAHVIGRDCSRCATGY-------WGFPNCRPCDC-GARLCDELTGQCICPPR 1503
P+ QC C G+ C CA+GY F C PC+C G CD TG C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDE 436
Query: 1504 TIPPDCLLCQPQTFG-CHPLVGCEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRC 1561
+C C + H C+ C C G P +T+ C C P VTG RC
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHN-GFSCSVMP--ETEEVVCNNCPPGVTGARC 493
Query: 1562 DTCSPGFHGYP--------RCRPCDCHE--AGTAPGVCDPLTGQCY-CKENVQGPKCDQC 1610
+ C+ G+ G P C+PC C+ +A G CD LTG+C C N G CDQC
Sbjct: 494 ELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQC 553
Query: 1611 SLGTFSLD-AANPKG-CTRCFC 1630
G F A NP C C C
Sbjct: 554 KAGYFGDPLAPNPADKCRACNC 575
Score = 90.9 bits (224), Expect = 2e-17
Identities = 66/228 (28%), Positives = 89/228 (39%), Gaps = 29/228 (12%)
Query: 604 RCLCQPEFAGPHCDRCRPGYHG-------FPNCQACTCDPRGALDQLCGAGGLCRCRPGY 656
+C+C + G C C GY F C C C GA D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD---CYSGDEN 437
Query: 657 TGTACQECSPGFHGFP----SCVPCHCSAEGSLHAACDPRSGQCS-CRPRVTGLRCDTCV 711
C +C GF+ P SC PC C S + C+ C P VTG RC+ C
Sbjct: 438 PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 712 PGAYNFPYCEAGSCHPAGLAPVDPAL-PEAQVPC--------MCRAHVEGPSCDRCKPGF 762
G + P+ E G P + + P A C C + G CD+CK G+
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 763 WG--LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC 808
+G L+P+ + C C+C+ G+ C+ G C CKP G C
Sbjct: 558 FGDPLAPNPADKCRACNCNPMGS--EPVGCR-SDGTCVCKPGFGGPNC 602
Score = 90.1 bits (222), Expect = 4e-17
Identities = 49/152 (32%), Positives = 64/152 (42%), Gaps = 29/152 (19%)
Query: 562 CRVGFEGATCDRCAPGYFHF---PLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDR 618
C +G C++C G++ C C C+ G+L CD +GRC C+P G CDR
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDR 115
Query: 619 CRPGYHGFPNC----------QACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGF 668
C PG+H + C CDP G C A G C C+P TG C C G+
Sbjct: 116 CLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CDA-GRCVCKPAVTGERCDRCRSGY 173
Query: 669 HGF-----PSCVPCHC---------SAEGSLH 686
+ C C C SAE S+H
Sbjct: 174 YNLDGGNPEGCTQCFCYGHSASCRSSAEYSVH 205
Score = 85.5 bits (210), Expect = 9e-16
Identities = 48/144 (33%), Positives = 61/144 (42%), Gaps = 19/144 (13%)
Query: 2040 CL-CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQ 2098
CL C G C++C+ G + C PC C S SG+C C+PG G +
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGAR 112
Query: 2099 CRECAPGYWGLPEQGC--------RRCQC-PGGRCDP-HTGRCNCPPGLSGERCDTCSQQ 2148
C C PG+ L + GC +C C P G P GRC C P ++GERCD C
Sbjct: 113 CDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSG 172
Query: 2149 HQVPVPGGP--------VGHSIHC 2164
+ G P GHS C
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASC 196
Score = 78.6 bits (192), Expect = 1e-13
Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 22/164 (13%)
Query: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF---PYCEAGSCHPAGLAPVDP 735
C + LH +C G+ C+ C G Y C +C+ G
Sbjct: 37 CIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--- 93
Query: 736 ALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCT--------RCSCDLRGTLGGV 787
A + C C+ V G CDRC PGF L+ + GCT +C CD G G
Sbjct: 94 ARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIAG-- 148
Query: 788 AECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
C G+C CKP V G+ C C+ G++ LD + GC C C
Sbjct: 149 -PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 72.0 bits (175), Expect = 1e-11
Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 23/174 (13%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C CH + +C T+ + C C G C+ C G+ P+ CQ
Sbjct: 462 CPCH-NGFSCSVMPETE--EVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQP 516
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C + DP AS + D G C+ C H+T G+ C++C G++ P
Sbjct: 517 CQCNNNV-----DPS-----ASGNCDRLT---GRCLKCIHNTAGIYCDQCKAGYFGDPLA 563
Query: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCY 472
P + CR CNC ++ G C C+P F G C+ G P+CY
Sbjct: 564 P-NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPACY 613
Score = 58.9 bits (141), Expect = 9e-08
Identities = 53/187 (28%), Positives = 70/187 (37%), Gaps = 35/187 (18%)
Query: 695 QCSCRPRVTGLRCDTCVPG-----AYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAH 749
QC C G C C G A P+ C+ G DP + C +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD------CYSG 434
Query: 750 VEGPS--CDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCK---PHVC 804
E P C C GF+ P +P C C C G P T + C P V
Sbjct: 435 DENPDIECADCPIGFYN-DPHDPRSCKPCPCHN----GFSCSVMPETEEVVCNNCPPGVT 489
Query: 805 GQACASCKDGFFGLDQADYFG-------CRSCRC--DIGGALGQSCEPRTGVC-RCRPNT 854
G C C DG+FG D FG C+ C+C ++ + +C+ TG C +C NT
Sbjct: 490 GARCELCADGYFG----DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
Query: 855 QGPTCSE 861
G C +
Sbjct: 546 AGIYCDQ 552
Score = 50.4 bits (119), Expect = 3e-05
Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 25/124 (20%)
Query: 1430 FYNNGAR----PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNC---- 1481
FY + R PC C+ G+ C+ G+C C V G C RC G+ +
Sbjct: 72 FYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 1482 ------RPCDCG----ARLCDELTGQCICPPRTIPPDCLLCQPQTF---GCHPLVGCEEC 1528
CDC A CD G+C+C P C C+ + G +P GC +C
Sbjct: 131 DQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNP-EGCTQC 187
Query: 1529 NCSG 1532
C G
Sbjct: 188 FCYG 191
Score = 47.4 bits (111), Expect = 3e-04
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 791 QPGTG-QCF-CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVC 848
Q G G +C C + G C CK+GF+ + D C C C+ G+L C+ +G C
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARCD-NSGRC 102
Query: 849 RCRPNTQGPTCSEPARDHYLPDLHHL 874
C+P G C D LP H L
Sbjct: 103 SCKPGVTGARC-----DRCLPGFHML 123
Score = 46.6 bits (109), Expect = 5e-04
Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 26/113 (23%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC--YGHATDCYYDPEVDRRR 378
+C+C+ G CDRC PGF+ T + C+C G A C
Sbjct: 101 RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---------- 150
Query: 379 ASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC 431
G C+ C+ TG C+RC G+Y N +P C +C C
Sbjct: 151 ----------DAGRCV-CKPAVTGERCDRCRSGYY---NLDGGNPEGCTQCFC 189
Score = 45.1 bits (105), Expect = 0.001
Identities = 41/160 (25%), Positives = 49/160 (30%), Gaps = 68/160 (42%)
Query: 2068 RPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWG-----LPEQGCRRCQCP-G 2121
RP + PA P QC C G G C++CA GY P C C C G
Sbjct: 369 RPVSGAPA-------PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG 421
Query: 2122 GRCDPHTGRC-------------------------------------------------- 2131
G CDP TG C
Sbjct: 422 GACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC 481
Query: 2132 -NCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHC 2170
NCPPG++G RC+ C+ + G P G C C
Sbjct: 482 NNCPPGVTGARCELCADGYF----GDPFGEHGPVRPCQPC 517
Score = 41.2 bits (95), Expect = 0.019
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQ 1497
C C G GP C+ G+C C V G C RC +GY+ P C C +
Sbjct: 139 CDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Query: 1498 C 1498
C
Sbjct: 196 C 196
Score = 40.0 bits (92), Expect = 0.043
Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 19/96 (19%)
Query: 296 IGGRCVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSA 353
+ +C C G A CDA +C C+ G CDRC G+ +
Sbjct: 135 LDSKCDCDPAGIAGPCDAG--------RCVCKPAVTGERCDRCRSGYYN-----LDGGNP 181
Query: 354 NECQSCNCYGHATDCYYDPEVDRRRAS----QSLDG 385
C C CYGH+ C E + + Q +DG
Sbjct: 182 EGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDG 217
Score = 36.2 bits (82), Expect = 0.62
Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 792 PGTGQCFCKPHVCGQACASCKDGFFGLDQADY--FG-CRSCRCDIGGALGQSCEPRTGVC 848
P QC C GQ C C G + D A FG C C C GGA C+P TG C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDC 431
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 293 bits (751), Expect = 2e-78
Identities = 201/597 (33%), Positives = 271/597 (45%), Gaps = 78/597 (13%)
Query: 1509 CLLCQPQTFGCH------------PLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNV 1556
CL C T G H C CNC+ G CD +SG+C C+P V
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGS---LSARCD-NSGRCSCKPGV 108
Query: 1557 TGRRCDTCSPGFHGYPRC----------RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
TG RCD C PGFH CDC AG A G CD G+C CK V G +
Sbjct: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGER 165
Query: 1607 CDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSS------YTRQEFVDMEGWVLLSTDR 1660
CD+C G ++LD NP+GCT+CFC+G + CRSS+ T D++GW +
Sbjct: 166 CDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAV---- 221
Query: 1661 QVVPHERQPGTEMLRADLRHVPE-AVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSE 1719
+R L+ RH + + +Y+ AP +LG++ SYG +L ++
Sbjct: 222 -----QRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD---- 272
Query: 1720 TQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRN--- 1776
R D S DV+L+G + IT P P + G + + N
Sbjct: 273 -YRVDRGGRHPSAHDVILEGAGLRIT--APLMPLGKTLPCGLTKTYTFRLNEHPSNNWSP 329
Query: 1777 TVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPAS 1836
+S E +L +L L+IRA + + S+ ++ V L A P GA A VE C+CP
Sbjct: 330 QLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARPV-SGAPAPWVEQCICPVG 387
Query: 1837 YRGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERC 1895
Y+G CQ+CA G+ RD L G C+PC C G C P +G C N + C C
Sbjct: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECADC 445
Query: 1896 QAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQC-LCKPGYAGASCERCAPG 1954
GF + DP + C CPC N F+ + C C PG GA CE CA G
Sbjct: 446 PIGFYNDPHDPRS-CKPCPC-----HNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
Query: 1955 FFGNPLVLGS---SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+FG+P CQPC C+ N DP+ +CD LTG C C+ +T G C+ C G++
Sbjct: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPS-ASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 2012 GNALLPG---NCTRCDCTPCGTEACDPHS-GHCLCKAGVTGRRCDRCQEGHFGFDGC 2064
G+ L P C C+C P G+E S G C+CK G G C+ G F C
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG---PNCEHGAFSCPAC 612
Score = 125 bits (313), Expect = 1e-27
Identities = 88/273 (32%), Positives = 113/273 (41%), Gaps = 55/273 (20%)
Query: 393 CIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPN 452
CI C G C+ C G Y+ + L C CNC+ G C+ TG CY
Sbjct: 382 CI-CPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYSGDE 436
Query: 453 FSGERCDVCAEGFTGFP----SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK 508
C C GF P SC P P N V+P + V C+
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNN------------ 483
Query: 509 DPRVGRCLCKPNFQGTHCELCAPGFYGPG---------CQPCQCSS--PGVADDRCDPDT 557
C P G CELCA G++G CQPCQC++ A CD T
Sbjct: 484 --------CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLT 535
Query: 558 GQC-RCRVGFEGATCDRCAPGYFHFPL-------CQLCGCSPAGTLPEGCDEAGRCLCQP 609
G+C +C G CD+C GYF PL C+ C C+P G+ P GC G C+C+P
Sbjct: 536 GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKP 595
Query: 610 EFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQ 642
F GP+C+ HG +C AC + +DQ
Sbjct: 596 GFGGPNCE------HGAFSCPACYNQVKIQMDQ 622
Score = 115 bits (287), Expect = 1e-24
Identities = 64/173 (36%), Positives = 88/173 (50%), Gaps = 33/173 (19%)
Query: 630 QACTCDPRGA-------LDQLCGAGGLC-RCRPGYTGTACQECSPGFHGFPS---CVPCH 678
+ C C+ + L + G G C C G C++C GF+ C+PC+
Sbjct: 26 EVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
Query: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAG------------SCH 726
C+++GSL A CD SG+CSC+P VTG RCD C+PG + +AG C
Sbjct: 86 CNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLT--DAGCTQDQRLLDSKCDCD 142
Query: 727 PAGLA-PVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
PAG+A P D C+C+ V G CDRC+ G++ L NPEGCT+C C
Sbjct: 143 PAGIAGPCDAGR------CVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 114 bits (286), Expect = 1e-24
Identities = 79/260 (30%), Positives = 106/260 (40%), Gaps = 54/260 (20%)
Query: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA 505
+C C + G+ C CA G+ ++ P G + C+C G A
Sbjct: 381 QCICPVGYKGQFCQDCASGY-------------KRDSARLGPFGTCIPCNCQGGG----A 423
Query: 506 CRKDPRVGRCLCKPNFQGTHCELCAPGFYGP-----GCQPCQCSSPGVADDRCDPDTGQC 560
C DP G C C C GFY C+PC C + + + C
Sbjct: 424 C--DPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC 481
Query: 561 R-CRVGFEGATCDRCAPGYFHFPL--------CQLCGCS----PAGTLPEGCDE-AGRCL 606
C G GA C+ CA GYF P CQ C C+ P+ + CD GRCL
Sbjct: 482 NNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS--GNCDRLTGRCL 539
Query: 607 -CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAGGLCRCRPGYTG 658
C AG +CD+C+ GY G P C+AC C+P G+ C + G C C+PG+ G
Sbjct: 540 KCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG 599
Query: 659 TACQECSPGFHGFPSCVPCH 678
C+ HG SC C+
Sbjct: 600 PNCE------HGAFSCPACY 613
Score = 111 bits (277), Expect = 2e-23
Identities = 67/178 (37%), Positives = 82/178 (46%), Gaps = 31/178 (17%)
Query: 485 VLPAGQIVN----CDCSAAGTQ----GNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG 535
+LPA + + CDC+ Q R+ RCL C N G HCE C GFY
Sbjct: 15 LLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR 74
Query: 536 ----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFP--------- 582
C PC C+S G RCD ++G+C C+ G GA CDRC PG+
Sbjct: 75 HRERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQR 133
Query: 583 -LCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGF-----PNCQACTC 634
L C C PAG + CD AGRC+C+P G CDRCR GY+ C C C
Sbjct: 134 LLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 110 bits (276), Expect = 2e-23
Identities = 73/232 (31%), Positives = 94/232 (40%), Gaps = 25/232 (10%)
Query: 650 CRCRPGYTGTACQECSPGFHG-------FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRV 702
C C GY G CQ+C+ G+ F +C+PC+C G ACDP +G C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCYSGDEN 437
Query: 703 TGLRCDTCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRC 758
+ C C G YN P+ C+ CH V P E V C V G C+ C
Sbjct: 438 PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEV-VCNNCPPGVTGARCELC 496
Query: 759 KPGFWGLSPSNPEG----CTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKD 813
G++G P G C C C+ C TG+C C + G C CK
Sbjct: 497 ADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 814 GFFG--LDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPA 863
G+FG L CR+C C+ G+ C G C C+P GP C A
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
Score = 105 bits (263), Expect = 6e-22
Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 35/200 (17%)
Query: 350 ANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCL 409
A + + + C+C G + C +D E+ R+ + G C++C +T G++CE+C
Sbjct: 19 ARATSRREVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCEKCK 69
Query: 410 PGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
GFYR C CNC S + D +GRC C+P +G RCD C GF
Sbjct: 70 NGFYRHRERDR-----CLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHML- 123
Query: 470 SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
+ + T++Q L + CDC AG G GRC+CKP G C+ C
Sbjct: 124 ------TDAGCTQDQRLLDSK---CDCDPAGIAGPC-----DAGRCVCKPAVTGERCDRC 169
Query: 530 APGFYG------PGCQPCQC 543
G+Y GC C C
Sbjct: 170 RSGYYNLDGGNPEGCTQCFC 189
Score = 97.4 bits (241), Expect = 2e-19
Identities = 70/240 (29%), Positives = 92/240 (38%), Gaps = 51/240 (21%)
Query: 555 PDTGQCRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCL 606
P QC C VG++G C CA GY F C C C G CD + G C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCY 432
Query: 607 CQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC------------RCRP 654
E C C G++ P+ DPR C G C C P
Sbjct: 433 SGDENPDIECADCPIGFYNDPH------DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPP 486
Query: 655 GYTGTACQECSPGFHGFP--------SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVT 703
G TG C+ C+ G+ G P C PC C + + S CD +G+C C
Sbjct: 487 GVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA 546
Query: 704 GLRCDTCVPGAYNFPY-------CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756
G+ CD C G + P C A +C+P G PV + C+C+ GP+C+
Sbjct: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVG---CRSDGTCVCKPGFGGPNCE 603
Score = 96.7 bits (239), Expect = 4e-19
Identities = 173/761 (22%), Positives = 270/761 (35%), Gaps = 144/761 (18%)
Query: 2000 GPRCEICAPGFYGNA--LLP-GNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQE 2056
G C+ CA G+ ++ L P G C C+C G ACDP +G C C C
Sbjct: 390 GQFCQDCASGYKRDSARLGPFGTCIPCNCQ--GGGACDPDTGDCYSGDENPDIECADCPI 447
Query: 2057 GHFGFD-GCGGCRPCACGPAAEGSECH--PQSGQC---HCRPGTMGPQCRECAPGYWGLP 2110
G + C+PC C G C P++ + +C PG G +C CA GY+G P
Sbjct: 448 GFYNDPHDPRSCKPCPCH---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDP 504
Query: 2111 --EQG----CRRCQC-------PGGRCDPHTGRC-NCPPGLSGERCDTCSQQH------- 2149
E G C+ CQC G CD TGRC C +G CD C +
Sbjct: 505 FGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
Query: 2150 ----------QVPVPGGPVG--------------------HSIHCEVCDHCVVLLLD--- 2176
P+ PVG + C C + V + +D
Sbjct: 565 NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFM 624
Query: 2177 -DLERAGALL-----------------------PAIHEQLRGINASSMAWARLHRLNASI 2212
L+R AL+ A+ + LR S A L A +
Sbjct: 625 QQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKV 684
Query: 2213 ADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATL 2272
++ +S L T +++ L Q + +D RL Q LA +EA+L
Sbjct: 685 RSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRL-------ITQMQLSLAESEASL 737
Query: 2273 GHAKTLLAAIRAVDRTLSELMSQTGHLGLANA-SAPSGEQLLRTLAEVER--LLWEMRAR 2329
G+ + L + L ++ SA + EQL R + + L +A
Sbjct: 738 GNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKAL 797
Query: 2330 DLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTR---DRLAQHEAGLMDLRE 2386
G + + A Q L+ ++ E+ SL ++ ATQ DR QH L+D
Sbjct: 798 HEGVGSGSGSPDGAVVQGLVEKL-EKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVS 856
Query: 2387 ALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHS 2446
L D + + +EEA + KQ+ D+ + T H + R +
Sbjct: 857 RLQGVSDQSFQ-----------VEEAKRIKQK--ADSLSSLVTRH-----MDEFKRTQKN 898
Query: 2447 LDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLR-LVEAAEAHAQQLGQLALNLSSI 2505
L KEE ++L + R Q + + A S+ + + A ++ + NL
Sbjct: 899 LGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREF 958
Query: 2506 ILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQL 2565
L V+ R EA A R+ Q DA+ + QQA+ + RA+
Sbjct: 959 DLQVD-----NRKAEAEEAMKRLSYISQKVSDASDKT-QQAERALGSAAAD--AQRAKNG 1010
Query: 2566 LANSTALEEAMLQEQQRLGL-----------VWAALQGARTQLRDVRAKKDQLEAHIQAA 2614
+ + + QE L L + L ++++R+V + ++ E
Sbjct: 1011 AGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTN 1070
Query: 2615 QAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQE 2655
+ M E K AK QDT + L M +
Sbjct: 1071 MDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQ 1111
Score = 94.4 bits (233), Expect = 2e-18
Identities = 69/202 (34%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Query: 1452 PFGGQCPCHAHVIGRDCSRCATGY-------WGFPNCRPCDC-GARLCDELTGQCICPPR 1503
P+ QC C G+ C CA+GY F C PC+C G CD TG C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDE 436
Query: 1504 TIPPDCLLCQPQTFG-CHPLVGCEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRC 1561
+C C + H C+ C C G P +T+ C C P VTG RC
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHN-GFSCSVMP--ETEEVVCNNCPPGVTGARC 493
Query: 1562 DTCSPGFHGYP--------RCRPCDCHE--AGTAPGVCDPLTGQCY-CKENVQGPKCDQC 1610
+ C+ G+ G P C+PC C+ +A G CD LTG+C C N G CDQC
Sbjct: 494 ELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQC 553
Query: 1611 SLGTFSLD-AANPKG-CTRCFC 1630
G F A NP C C C
Sbjct: 554 KAGYFGDPLAPNPADKCRACNC 575
Score = 90.9 bits (224), Expect = 2e-17
Identities = 66/228 (28%), Positives = 89/228 (39%), Gaps = 29/228 (12%)
Query: 604 RCLCQPEFAGPHCDRCRPGYHG-------FPNCQACTCDPRGALDQLCGAGGLCRCRPGY 656
+C+C + G C C GY F C C C GA D G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD---CYSGDEN 437
Query: 657 TGTACQECSPGFHGFP----SCVPCHCSAEGSLHAACDPRSGQCS-CRPRVTGLRCDTCV 711
C +C GF+ P SC PC C S + C+ C P VTG RC+ C
Sbjct: 438 PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 712 PGAYNFPYCEAGSCHPAGLAPVDPAL-PEAQVPC--------MCRAHVEGPSCDRCKPGF 762
G + P+ E G P + + P A C C + G CD+CK G+
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 763 WG--LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC 808
+G L+P+ + C C+C+ G+ C+ G C CKP G C
Sbjct: 558 FGDPLAPNPADKCRACNCNPMGS--EPVGCR-SDGTCVCKPGFGGPNC 602
Score = 90.1 bits (222), Expect = 4e-17
Identities = 49/152 (32%), Positives = 64/152 (42%), Gaps = 29/152 (19%)
Query: 562 CRVGFEGATCDRCAPGYFHF---PLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDR 618
C +G C++C G++ C C C+ G+L CD +GRC C+P G CDR
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDR 115
Query: 619 CRPGYHGFPNC----------QACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGF 668
C PG+H + C CDP G C A G C C+P TG C C G+
Sbjct: 116 CLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CDA-GRCVCKPAVTGERCDRCRSGY 173
Query: 669 HGF-----PSCVPCHC---------SAEGSLH 686
+ C C C SAE S+H
Sbjct: 174 YNLDGGNPEGCTQCFCYGHSASCRSSAEYSVH 205
Score = 85.5 bits (210), Expect = 9e-16
Identities = 48/144 (33%), Positives = 61/144 (42%), Gaps = 19/144 (13%)
Query: 2040 CL-CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQ 2098
CL C G C++C+ G + C PC C S SG+C C+PG G +
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGAR 112
Query: 2099 CRECAPGYWGLPEQGC--------RRCQC-PGGRCDP-HTGRCNCPPGLSGERCDTCSQQ 2148
C C PG+ L + GC +C C P G P GRC C P ++GERCD C
Sbjct: 113 CDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSG 172
Query: 2149 HQVPVPGGP--------VGHSIHC 2164
+ G P GHS C
Sbjct: 173 YYNLDGGNPEGCTQCFCYGHSASC 196
Score = 78.6 bits (192), Expect = 1e-13
Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 22/164 (13%)
Query: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF---PYCEAGSCHPAGLAPVDP 735
C + LH +C G+ C+ C G Y C +C+ G
Sbjct: 37 CIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLS--- 93
Query: 736 ALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCT--------RCSCDLRGTLGGV 787
A + C C+ V G CDRC PGF L+ + GCT +C CD G G
Sbjct: 94 ARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGIAG-- 148
Query: 788 AECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
C G+C CKP V G+ C C+ G++ LD + GC C C
Sbjct: 149 -PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 72.0 bits (175), Expect = 1e-11
Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 23/174 (13%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C CH + +C T+ + C C G C+ C G+ P+ CQ
Sbjct: 462 CPCH-NGFSCSVMPETE--EVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQP 516
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
C C + DP AS + D G C+ C H+T G+ C++C G++ P
Sbjct: 517 CQCNNNV-----DPS-----ASGNCDRLT---GRCLKCIHNTAGIYCDQCKAGYFGDPLA 563
Query: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCY 472
P + CR CNC ++ G C C+P F G C+ G P+CY
Sbjct: 564 P-NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPACY 613
Score = 58.9 bits (141), Expect = 9e-08
Identities = 53/187 (28%), Positives = 70/187 (37%), Gaps = 35/187 (18%)
Query: 695 QCSCRPRVTGLRCDTCVPG-----AYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAH 749
QC C G C C G A P+ C+ G DP + C +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGD------CYSG 434
Query: 750 VEGPS--CDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCK---PHVC 804
E P C C GF+ P +P C C C G P T + C P V
Sbjct: 435 DENPDIECADCPIGFYN-DPHDPRSCKPCPCHN----GFSCSVMPETEEVVCNNCPPGVT 489
Query: 805 GQACASCKDGFFGLDQADYFG-------CRSCRC--DIGGALGQSCEPRTGVC-RCRPNT 854
G C C DG+FG D FG C+ C+C ++ + +C+ TG C +C NT
Sbjct: 490 GARCELCADGYFG----DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
Query: 855 QGPTCSE 861
G C +
Sbjct: 546 AGIYCDQ 552
Score = 50.4 bits (119), Expect = 3e-05
Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 25/124 (20%)
Query: 1430 FYNNGAR----PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNC---- 1481
FY + R PC C+ G+ C+ G+C C V G C RC G+ +
Sbjct: 72 FYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 1482 ------RPCDCG----ARLCDELTGQCICPPRTIPPDCLLCQPQTF---GCHPLVGCEEC 1528
CDC A CD G+C+C P C C+ + G +P GC +C
Sbjct: 131 DQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNP-EGCTQC 187
Query: 1529 NCSG 1532
C G
Sbjct: 188 FCYG 191
Score = 47.4 bits (111), Expect = 3e-04
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 791 QPGTG-QCF-CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVC 848
Q G G +C C + G C CK+GF+ + D C C C+ G+L C+ +G C
Sbjct: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARCD-NSGRC 102
Query: 849 RCRPNTQGPTCSEPARDHYLPDLHHL 874
C+P G C D LP H L
Sbjct: 103 SCKPGVTGARC-----DRCLPGFHML 123
Score = 46.6 bits (109), Expect = 5e-04
Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 26/113 (23%)
Query: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC--YGHATDCYYDPEVDRRR 378
+C+C+ G CDRC PGF+ T + C+C G A C
Sbjct: 101 RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---------- 150
Query: 379 ASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC 431
G C+ C+ TG C+RC G+Y N +P C +C C
Sbjct: 151 ----------DAGRCV-CKPAVTGERCDRCRSGYY---NLDGGNPEGCTQCFC 189
Score = 45.1 bits (105), Expect = 0.001
Identities = 41/160 (25%), Positives = 49/160 (30%), Gaps = 68/160 (42%)
Query: 2068 RPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWG-----LPEQGCRRCQCP-G 2121
RP + PA P QC C G G C++CA GY P C C C G
Sbjct: 369 RPVSGAPA-------PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG 421
Query: 2122 GRCDPHTGRC-------------------------------------------------- 2131
G CDP TG C
Sbjct: 422 GACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC 481
Query: 2132 -NCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHC 2170
NCPPG++G RC+ C+ + G P G C C
Sbjct: 482 NNCPPGVTGARCELCADGYF----GDPFGEHGPVRPCQPC 517
Score = 41.2 bits (95), Expect = 0.019
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQ 1497
C C G GP C+ G+C C V G C RC +GY+ P C C +
Sbjct: 139 CDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
Query: 1498 C 1498
C
Sbjct: 196 C 196
Score = 40.0 bits (92), Expect = 0.043
Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 19/96 (19%)
Query: 296 IGGRCVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSA 353
+ +C C G A CDA +C C+ G CDRC G+ +
Sbjct: 135 LDSKCDCDPAGIAGPCDAG--------RCVCKPAVTGERCDRCRSGYYN-----LDGGNP 181
Query: 354 NECQSCNCYGHATDCYYDPEVDRRRAS----QSLDG 385
C C CYGH+ C E + + Q +DG
Sbjct: 182 EGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDG 217
Score = 36.2 bits (82), Expect = 0.62
Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 792 PGTGQCFCKPHVCGQACASCKDGFFGLDQADY--FG-CRSCRCDIGGALGQSCEPRTGVC 848
P QC C GQ C C G + D A FG C C C GGA C+P TG C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDC 431
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 285 bits (730), Expect = 4e-76
Identities = 184/598 (30%), Positives = 273/598 (45%), Gaps = 93/598 (15%)
Query: 23 LLVGLALLGAARAREEAGGGFSLHPPYFNLAEG--ARIAASATCGEEAPARGSPRPTEDL 80
L + L L ++A+++ G + HP +L G ++ AS+TCG +
Sbjct: 7 LFLHLGWLSYSKAQDDCNRG-ACHPTTGDLLVGRNTQLMASSTCGLSRAQK--------- 56
Query: 81 YCKLVGGPVAGGDPNQTIRG-QYCDICTAA------NSNKAHPASNAI-----DGTERWW 128
YC L + G Q C IC + + +H N I D ++WW
Sbjct: 57 YCIL-----------SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWW 105
Query: 129 QSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFF 188
QS GL++ V++ LDL +F +++++ F RP ++ERS D+G ++ +++F
Sbjct: 106 QS---ENGLDH--VSIRLDLEALFRFSHLILTFKTF-RPAAMLVERSTDYGHNWKVFKYF 159
Query: 189 ASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSP 248
A +DC F T + +C ++YS I P GE+V+ +++ N YSP
Sbjct: 160 A---KDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIEN-PYSP 215
Query: 249 LLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADA 308
+++ TN+R+ F + +TL L+G+ D +YYY++ ++ + G C C+GHA
Sbjct: 216 YIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSL--DKYYYALYEMIVRGSCFCNGHASE 273
Query: 309 C--------DAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
C D P QC CQHNT G C+RC F PW+PA N C+SC+
Sbjct: 274 CRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCS 333
Query: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
C H++ C++D + AS L GGVC DCQH+T G +C+RC P FYR P +
Sbjct: 334 CNSHSSRCHFD--MTTYLASGGL-----SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTI 386
Query: 421 DSPHVCRRCNCESDFT----------DGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPS 470
P+ C C C+ D T D + G+C C+ N G +CD C G +
Sbjct: 387 SDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSA 446
Query: 471 CYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCA 530
P CDC+ G+ D G+CLC G HCE C
Sbjct: 447 TDPLGCQP---------------CDCNPLGSL-PFLTCDVDTGQCLCLSYVTGAHCEECT 490
Query: 531 PGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL 583
G++G GC PC C G + C P GQC CR G +C APGYF PL
Sbjct: 491 VGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPL 548
Score = 248 bits (632), Expect = 1e-64
Identities = 145/411 (35%), Positives = 186/411 (45%), Gaps = 48/411 (11%)
Query: 492 VNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGV 548
V C C G+ G++C + G+C CKP G C+ C+ G Y GC PC C G
Sbjct: 767 VACKCHPQGSVGSSCSR--LGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
Query: 549 ADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCL- 606
D CD TGQC C G CDRC GYF FP C C C+ E CD E G C
Sbjct: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCN---RFAELCDPETGSCFN 881
Query: 607 CQPEFAGPHCDRCRPGYHGFPN----CQACTC--DP-------RGALDQLCGAGGLCRCR 653
C G +C+RC GY+G P+ C+ C C DP L + +C C
Sbjct: 882 CGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCL 941
Query: 654 PGYTGTACQECSPGFHGFP-----SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVTGL 705
GYTGT C ECS GF+G P C PC C + + + +C +G+C C G
Sbjct: 942 QGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
Query: 706 RCDTCVPGAYNFPY---CEAGSCHPAGLAPVD-------PALPEAQVPCMCRAHVEGPSC 755
C C PG Y C SCH +G++P++ C C +V G +C
Sbjct: 1002 NCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC 1061
Query: 756 DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGF 815
DRC G+W L P GC C CD R + + C TGQC CK G+ C+ C++ +
Sbjct: 1062 DRCADGYWNLVPG--RGCQSCDCDPRTSQS--SHCDQLTGQCPCKLGYGGKRCSECQENY 1117
Query: 816 FGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
+G C C C+ G C+P TG+CRCR G C AR H
Sbjct: 1118 YGDPPG---RCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGH 1165
Score = 246 bits (627), Expect = 4e-64
Identities = 142/425 (33%), Positives = 191/425 (44%), Gaps = 53/425 (12%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGA 1890
C C G C C G++ C PC C+ ++ C P +G C +C T G
Sbjct: 836 CPCHGEVSGRRCDRCLAGYFG------FPSCHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
Query: 1891 HCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNN-FAEGCV--LRGGRTQCLCKPGYAGAS 1947
+CERC G+ + PC C CP SN FA C L C C GY G
Sbjct: 890 NCERCIDGYYGNPSS-GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQ 948
Query: 1948 CERCAPGFFGNPLVLGSSCQPCDCSGN---GDPNLLFSDCDPLTGACRGCLRHTTGPRCE 2004
C C+ GF+GNP + G+ CQPC C+ N DP C +TG C CL +T G C+
Sbjct: 949 CGECSTGFYGNPRISGAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQ 1004
Query: 2005 ICAPGFYGNALLPGNCTRCDCTPCGTE-----------ACDPHSGHCLCKAGVTGRRCDR 2053
+C PG YG+A L C RC C G CDP +G C C VTG CDR
Sbjct: 1005 LCKPGHYGSA-LNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDR 1063
Query: 2054 CQEGHFGFDGCGGCRPCACGP-AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ 2112
C +G++ GC+ C C P ++ S C +GQC C+ G G +C EC Y+G P
Sbjct: 1064 CADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPG 1123
Query: 2113 GCRRCQCPGGR-----CDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVC 2167
C C C CDP TG C C G+SG+RCD C++ H P + C +C
Sbjct: 1124 RCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFP-----TCLQCHLC 1178
Query: 2168 ----DHCVVLL---LDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLR 2220
DH + L + L R A + E L + A L ++++++ L+
Sbjct: 1179 FDQWDHTISSLSKAVQGLMRLAANMEDKRETL------PVCEADFKDLRGNVSEIERILK 1232
Query: 2221 SPLGP 2225
P+ P
Sbjct: 1233 HPVFP 1237
Score = 212 bits (539), Expect = 6e-54
Identities = 136/403 (33%), Positives = 170/403 (42%), Gaps = 77/403 (19%)
Query: 390 GGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFT-DGTCEDLTGRCY 448
GG C C+ G C+RC G Y +H C C+C + D C+ +TG+C
Sbjct: 785 GGQC-QCKPLVVGRCCDRCSTGSYDLGHHG------CHPCHCHPQGSKDTVCDQVTGQCP 837
Query: 449 CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP-AGQIVNCDCSAAG------- 500
C SG RCD C G+ GFPSC+P P N E P G NC G
Sbjct: 838 CHGEVSGRRCDRCLAGYFGFPSCHPCP--CNRFAELCDPETGSCFNCGGFTTGRNCERCI 895
Query: 501 -------TQGNACR-----KDPRVGR----------------CLCKPNFQGTHCELCAPG 532
+ G CR DP + C C + GT C C+ G
Sbjct: 896 DGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTG 955
Query: 533 FY------GPGCQPCQCSSP-GVAD-DRCDPDTGQC-RCRVGFEGATCDRCAPGYFHFPL 583
FY G CQPC C++ V D + C TG+C RC +GA C C PG++ L
Sbjct: 956 FYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSAL 1015
Query: 584 ---CQLCGCSPAGTLPEGCDE----------AGRCLCQPEFAGPHCDRCRPGYHGF---P 627
C+ C C +G P C G C C P G CDRC GY
Sbjct: 1016 NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR 1075
Query: 628 NCQACTCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFP--SCVPCHCSAEGS 684
CQ+C CDPR + C G C C+ GY G C EC ++G P C+PC C+ G+
Sbjct: 1076 GCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGT 1135
Query: 685 LHAACDPRSGQCSCRPRVTGLRCDTCVPG-AYNFPYCEAGSCH 726
CDP +G C CR V+G RCD C G + FP C CH
Sbjct: 1136 QKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCL--QCH 1176
Score = 197 bits (501), Expect = 2e-49
Identities = 132/418 (31%), Positives = 171/418 (40%), Gaps = 81/418 (19%)
Query: 293 DISIGGRCVCHGHADACDAKDPT-DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
D+ G CH H +KD D QC C G CDRC G+ P
Sbjct: 808 DLGHHGCHPCHCHPQG--SKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP------- 858
Query: 352 SANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPG 411
C C C A C DPE G C +C TTG NCERC+ G
Sbjct: 859 ---SCHPCPCNRFAELC--DPET----------------GSCFNCGGFTTGRNCERCIDG 897
Query: 412 FYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGR---CYCRPNFSGERCDVCA 462
+Y +P+ S CR C C D F ++L C C ++G +C C+
Sbjct: 898 YYGNPS----SGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECS 953
Query: 463 EGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNF 521
GF G P P Q C+ + T +C + G CL C N
Sbjct: 954 TGFYGNPRISGAPC-------------QPCACNNNIDVTDPESCSR--VTGECLRCLHNT 998
Query: 522 QGTHCELCAPGFYGPG----CQPCQCSSPGVADDR---------CDPDTGQCRCRVGFEG 568
QG +C+LC PG YG C+ C C + GV+ CDP TG C C G
Sbjct: 999 QGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTG 1058
Query: 569 ATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYH 624
CDRCA GY++ CQ C C P + CD+ G+C C+ + G C C+ Y+
Sbjct: 1059 LACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY 1118
Query: 625 GFP--NCQACTCDPRGALDQLCGAG-GLCRCRPGYTGTACQECSPGF-HGFPSCVPCH 678
G P C C C+ G +C G+CRCR G +G C C+ G FP+C+ CH
Sbjct: 1119 GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCH 1176
Score = 196 bits (499), Expect = 3e-49
Identities = 119/361 (32%), Positives = 157/361 (43%), Gaps = 37/361 (10%)
Query: 537 GCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL--CQLCGCSPAGT 594
G C+C G C GQC+C+ G CDRC+ G + C C C P G+
Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
Query: 595 LPEGCDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCG--AGGLCR 651
CD+ G+C C E +G CDRC GY GFP+C C C+ +LC G
Sbjct: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCN---RFAELCDPETGSCFN 881
Query: 652 CRPGYTGTACQECSPGFHGFPS----CVPCHCSAEGSLHAACDPRSGQ--------CSCR 699
C TG C+ C G++G PS C PC C + S + Q C+C
Sbjct: 882 CGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCL 941
Query: 700 PRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAP-VDPALPEA----QVPCM-CRAHVEGP 753
TG +C C G Y P C P +D PE+ C+ C + +G
Sbjct: 942 QGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
Query: 754 SCDRCKPGFWGLSPSNPEGCTRCSCDLRGTL-------GGVAECQPGTGQCFCKPHVCGQ 806
+C CKPG +G + + + C RCSC G GG C P TG C C P+V G
Sbjct: 1002 NCQLCKPGHYGSALN--QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGL 1059
Query: 807 ACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
AC C DG++ L GC+SC CD + C+ TG C C+ G CSE ++
Sbjct: 1060 ACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENY 1117
Query: 867 Y 867
Y
Sbjct: 1118 Y 1118
Score = 179 bits (455), Expect = 3e-44
Identities = 128/412 (31%), Positives = 175/412 (42%), Gaps = 62/412 (15%)
Query: 603 GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
G+C+CQ GP+C+RC+ + P R A D AC+
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPW--------RPAAD--------------LQDNACR 330
Query: 663 ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCS-CRPRVTGLRCDTCVPGAYNFPY-- 719
CS H CH L A+ G C C+ G CD C P Y P
Sbjct: 331 SCSCNSHSSR----CHFDMTTYL-ASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKT 385
Query: 720 ------CEAGSCHPAG-------LAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLS 766
C C P G ++ DPAL C+C+ +VEG CD+CKP +GLS
Sbjct: 386 ISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLS 445
Query: 767 PSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 826
++P GC C C+ G+L + C TGQC C +V G C C G++GL GC
Sbjct: 446 ATDPLGCQPCDCNPLGSLPFLT-CDVDTGQCLCLSYVTGAHCEECTVGYWGLGN-HLHGC 503
Query: 827 RSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEG 886
C CDIGGA C P+ G C CRP+ G +CSEPA ++ L+ E EEA T +G
Sbjct: 504 SPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQG 563
Query: 887 HA----VRFGFN---------PLEFENFSWR--GYAQMAPVQPRIVARLNLTSPDLFWLV 931
A FG + P+ +W G+A++ P A N+ P F +
Sbjct: 564 LAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNIPFPVDFTIA 623
Query: 932 FRYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAF--PPSTEPAFITVP 981
Y + A + ++ V G S C T QS+P +F P +T + P
Sbjct: 624 IHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQSFALPAATRIMLLPTP 675
Score = 165 bits (417), Expect = 9e-40
Identities = 96/261 (36%), Positives = 126/261 (48%), Gaps = 27/261 (10%)
Query: 1824 LASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD-----RCLPGSG 1878
L S+ +C C Y G C EC+ GFY + + + C PC C+ + D C +G
Sbjct: 931 LWSSDVICNCLQGYTGTQCGECSTGFYGNPR-ISGAPCQPCACNNNIDVTDPESCSRVTG 989
Query: 1879 VCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC------PLSVPSNNFAEGCVLRG 1932
C+ C HNT+GA+C+ C+ G S + + C C C P+ P A C+
Sbjct: 990 ECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGA--CLCDP 1045
Query: 1933 GRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACR 1992
C C P G +C+RCA G++ LV G CQ CDC + S CD LTG C
Sbjct: 1046 VTGACPCLPNVTGLACDRCADGYWN--LVPGRGCQSCDCDPRTSQS---SHCDQLTGQC- 1099
Query: 1993 GCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE--ACDPHSGHCLCKAGVTGRR 2050
C G RC C +YG+ PG C CDC GT+ CDP +G C C+ GV+G+R
Sbjct: 1100 PCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQR 1157
Query: 2051 CDRCQEGHF-GFDGCGGCRPC 2070
CDRC GH F C C C
Sbjct: 1158 CDRCARGHSQEFPTCLQCHLC 1178
Score = 160 bits (404), Expect = 3e-38
Identities = 100/284 (35%), Positives = 131/284 (46%), Gaps = 38/284 (13%)
Query: 1864 CQCHGHSDRCLPGS--------------GVCVDCQHNTEGAHCERCQAGFVSSRDDPSAP 1909
C C+GH+ C P G CV CQHNT+G +CERC+ F + P+A
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
Query: 1910 -----CVSCPCPLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFFGNPL 1960
C SC C +F L G C C+ G C+RC P F+ +PL
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
Query: 1961 VLGS---SCQPCDCSGNG--DPNLLFSDCDPLTGACRG---CLRHTTGPRCEICAPGFYG 2012
S +C PC+C +G + S DP G+ G C + G +C+ C P YG
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
Query: 2013 -NALLPGNCTRCDCTPCGTE---ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDG-CGGC 2067
+A P C CDC P G+ CD +G CLC + VTG C+ C G++G GC
Sbjct: 444 LSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGC 503
Query: 2068 RPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 2110
PC C A + C P++GQC CRP G C E APGY+ P
Sbjct: 504 SPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 159 bits (403), Expect = 4e-38
Identities = 114/347 (32%), Positives = 137/347 (39%), Gaps = 72/347 (20%)
Query: 1862 VPCQCHGHSD---RCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLS 1918
V C+CH C G C C+ G C+RC G S D C C C
Sbjct: 767 VACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG---SYDLGHHGCHPCHCH-- 820
Query: 1919 VPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
P + C G QC C +G C+RC G+FG P SC PC C N
Sbjct: 821 -PQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPC------N 866
Query: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSG 2038
CDP TG+C C TTG CE C G+YGN C C C DP S
Sbjct: 867 RFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD------DPSSN 920
Query: 2039 H----------------CLCKAGVTGRRCDRCQEGHFGFDGCGG--CRPCACG---PAAE 2077
C C G TG +C C G +G G C+PCAC +
Sbjct: 921 QYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
Query: 2078 GSECHPQSGQC-HCRPGTMGPQCRECAPGYWGLP-EQGCRRCQC-----------PGG-- 2122
C +G+C C T G C+ C PG++G Q CRRC C PGG
Sbjct: 981 PESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGA 1040
Query: 2123 -RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCD 2168
CDP TG C C P ++G CD C+ + VPG C+ CD
Sbjct: 1041 CLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR------GCQSCD 1081
Score = 155 bits (393), Expect = 5e-37
Identities = 95/258 (36%), Positives = 120/258 (46%), Gaps = 37/258 (14%)
Query: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRC------------L 1874
C+C + G +C+ C F +R L C C C+ HS RC L
Sbjct: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
Query: 1875 PGSGVCVDCQHNTEGAHCERCQAGF----VSSRDDPSAPCVSCPCPLSVPSNNFAEG-CV 1929
G GVC DCQHNTEG HC+RC+ F + + DP A C+ C C P + G CV
Sbjct: 355 SG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA-CIPCECD---PDGTISGGICV 409
Query: 1930 ------LRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSD 1983
L QCLCK GA C++C P +G CQPCDC+ G +L F
Sbjct: 410 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLG--SLPFLT 467
Query: 1984 CDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCG--TEACDPHSGHCL 2041
CD TG C CL + TG CE C G++G C+ CDC G + C P +G C
Sbjct: 468 CDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCE 526
Query: 2042 CKAGVTGRRCDRCQEGHF 2059
C+ VTGR C G+F
Sbjct: 527 CRPHVTGRSCSEPAPGYF 544
Score = 143 bits (360), Expect = 4e-33
Identities = 81/217 (37%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCG--AR 1489
++G PC CH G+ C+ GQCPCH V GR C RC GY+GFP+C PC C A
Sbjct: 811 HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAE 870
Query: 1490 LCDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG--CEECNC-SGPGIQELTDPTCDT 1545
LCD TG C C T +C C +G +P G C C C P + +C
Sbjct: 871 LCDPETGSCFNCGGFTTGRNCERCIDGYYG-NPSSGQPCRPCLCPDDPSSNQYFAHSCYQ 929
Query: 1546 DSGQ----CKCRPNVTGRRCDTCSPGFHGYPR-----CRPCDCHE--AGTAPGVCDPLTG 1594
+ C C TG +C CS GF+G PR C+PC C+ T P C +TG
Sbjct: 930 NLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTG 989
Query: 1595 QCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
+C C N QG C C G + +A + C RC C
Sbjct: 990 ECLRCLHNTQGANCQLCKPGHYG--SALNQTCRRCSC 1024
Score = 140 bits (353), Expect = 2e-32
Identities = 83/256 (32%), Positives = 107/256 (41%), Gaps = 43/256 (16%)
Query: 1936 QCLCKPGYAGASCERCAPGFFGNPL-----VLGSSCQPCDCSGNG-----DPNLLFSDCD 1985
QC+C+ G +CERC F P + ++C+ C C+ + D +
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353
Query: 1986 PLTGACRGCLRHTTGPRCEICAPGFYGNALL----PGNCTRCDCTPCGTEA---CDPHS- 2037
G C C +T G C+ C P FY + L P C C+C P GT + C HS
Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413
Query: 2038 -------GHCLCKAGVTGRRCDRCQEGHFGFDGCG--GCRPCACGPAAEGS--ECHPQSG 2086
G CLCK V G +CD+C+ H+G GC+PC C P C +G
Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473
Query: 2087 QCHCRPGTMGPQCRECAPGYWGLPEQ--GCRRCQCPGGR-----CDPHTGRCNCPPGLSG 2139
QC C G C EC GYWGL GC C C G C P G+C C P ++G
Sbjct: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
Query: 2140 ERCDTCSQQHQVPVPG 2155
C P PG
Sbjct: 534 RSCSE-------PAPG 542
Score = 136 bits (343), Expect = 3e-31
Identities = 87/273 (31%), Positives = 112/273 (41%), Gaps = 63/273 (23%)
Query: 445 GRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSA------ 498
G+C C+ N G C+ C + F P N R +C C++
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACR----------SCSCNSHSSRCH 342
Query: 499 ---------AGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGP---------GCQP 540
G G C C+ N +G HC+ C P FY C P
Sbjct: 343 FDMTTYLASGGLSGGVCED--------CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP 394
Query: 541 CQCS-----SPGVADDRCDPD----TGQCRCRVGFEGATCDRCAPGYFHF----PL-CQL 586
C+C S G+ DP GQC C+ EGA CD+C P ++ PL CQ
Sbjct: 395 CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQP 454
Query: 587 CGCSPAGTLP-EGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPN----CQACTCDPRGAL 640
C C+P G+LP CD + G+CLC G HC+ C GY G N C C CD GA
Sbjct: 455 CDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAY 514
Query: 641 DQLCG-AGGLCRCRPGYTGTACQECSPGFHGFP 672
+C G C CRP TG +C E +PG+ P
Sbjct: 515 SNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 133 bits (334), Expect = 4e-30
Identities = 80/228 (35%), Positives = 105/228 (46%), Gaps = 32/228 (14%)
Query: 1430 FYNN----GA--RPCGCHE-VGATGP-TCEPFGGQC-PCHAHVIGRDCSRCATGYWGFP- 1479
FY N GA +PC C+ + T P +C G+C C + G +C C G++G
Sbjct: 956 FYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSAL 1015
Query: 1480 --NCRPCDC--------------GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLV 1523
CR C C GA LCD +TG C C P C C + P
Sbjct: 1016 NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR 1075
Query: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHE 1581
GC+ C+C Q CD +GQC C+ G+RC C ++G P RC PCDC+
Sbjct: 1076 GCQSCDCDPRTSQS---SHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNR 1132
Query: 1582 AGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCF 1629
AGT +CDP TG C C+E V G +CD+C+ G S + C CF
Sbjct: 1133 AGTQKPICDPDTGMCRCREGVSGQRCDRCARG-HSQEFPTCLQCHLCF 1179
Score = 127 bits (318), Expect = 3e-28
Identities = 85/291 (29%), Positives = 125/291 (42%), Gaps = 57/291 (19%)
Query: 1373 LDYVLVVPENVYSFGYLREEPLDKS--YDFISHCAAQGYHISPSSSSLFCRNAAASLSLF 1430
+D + ++P+ + ++ LD+ ++ + +A G + P + C S+S
Sbjct: 706 VDSLGLIPQINSLENFCSKQDLDEYQLHNCVEIASAMGPQVLPGA----CERLIISMSAK 761
Query: 1431 YNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYW--GFPNCRPCDCGA 1488
++GA C CH G+ G +C GGQC C V+GR C RC+TG + G C PC C
Sbjct: 762 LHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHP 821
Query: 1489 R-----LCDELTGQCICPPRTIPPDCLLCQPQTFG---CHPLVGCEECNCSGPGIQELTD 1540
+ +CD++TGQC C C C FG CHP C C+ EL
Sbjct: 822 QGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHP------CPCN--RFAEL-- 871
Query: 1541 PTCDTDSGQC-KCRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLTGQ 1595
CD ++G C C TGR C+ C G++G P CRPC C + DP + Q
Sbjct: 872 --CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD--------DPSSNQ 921
Query: 1596 ----------------CYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
C C + G +C +CS G + + C C C
Sbjct: 922 YFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCAC 972
Score = 106 bits (265), Expect = 4e-22
Identities = 66/227 (29%), Positives = 91/227 (40%), Gaps = 51/227 (22%)
Query: 1432 NNGARPCGCHEV---------------GATGPTCEPFGGQCPCHAHVIGRDCSRCATGYW 1476
+N R C C+ G +G CE C + G+ C RC ++
Sbjct: 326 DNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED------CQHNTEGQHCDRCRPLFY 379
Query: 1477 GFP--------NCRPCDC------GARLC--------DELTGQCICPPRTIPPDCLLCQP 1514
P C PC+C +C + GQC+C C C+P
Sbjct: 380 RDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKP 439
Query: 1515 QTFGCHPL--VGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP 1572
+G +GC+ C+C+ G L TCD D+GQC C VTG C+ C+ G+ G
Sbjct: 440 NHYGLSATDPLGCQPCDCNPLG--SLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
Query: 1573 R----CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1615
C PCDC G VC P GQC C+ +V G C + + G F
Sbjct: 498 NHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 96.7 bits (239), Expect = 4e-19
Identities = 68/218 (31%), Positives = 92/218 (42%), Gaps = 44/218 (20%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGA---RLCDELT------ 1495
GQC C + G +C RC + P CR C C + R ++T
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 1496 ----GQCI-CPPRTIPPDCLLCQPQTFGCHPL------VGCEECNC------SGPGIQEL 1538
G C C T C C+P F PL C C C SG
Sbjct: 353 GLSGGVCEDCQHNTEGQHCDRCRP-LFYRDPLKTISDPYACIPCECDPDGTISGGICVSH 411
Query: 1539 TDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPGV-CDPL 1592
+DP + +GQC C+ NV G +CD C P +G C+PCDC+ G+ P + CD
Sbjct: 412 SDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVD 471
Query: 1593 TGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
TGQC C V G C++C++G + L + GC+ C C
Sbjct: 472 TGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSPCDC 508
Score = 93.2 bits (230), Expect = 4e-18
Identities = 52/138 (37%), Positives = 63/138 (45%), Gaps = 22/138 (15%)
Query: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFH--GYPRCRPCDCHE 1581
G C C G +C GQC+C+P V GR CD CS G + G+ C PC CH
Sbjct: 765 GAVACKCHPQGS---VGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHP 821
Query: 1582 AGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTR-----------CF- 1629
G+ VCD +TGQC C V G +CD+C G F + +P C R CF
Sbjct: 822 QGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFN 881
Query: 1630 CFGAT-----ERCRSSSY 1642
C G T ERC Y
Sbjct: 882 CGGFTTGRNCERCIDGYY 899
Score = 84.7 bits (208), Expect = 2e-15
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 26/176 (14%)
Query: 1418 LFCRNAAASLSLFYNNGARPCGCHEVGA---------TGPTCEPFGGQCPCHAHVIGRDC 1468
LF R+ ++S Y PC C G + P GQC C +V G C
Sbjct: 377 LFYRDPLKTISDPY--ACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKC 434
Query: 1469 SRCATGYWGFP-----NCRPCDCGAR------LCDELTGQCICPPRTIPPDCLLCQPQTF 1517
+C ++G C+PCDC CD TGQC+C C C +
Sbjct: 435 DQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYW 494
Query: 1518 GC-HPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP 1572
G + L GC C+C G C +GQC+CRP+VTGR C +PG+ P
Sbjct: 495 GLGNHLHGCSPCDCDIGGAYS---NVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 81.3 bits (199), Expect = 2e-14
Identities = 70/250 (28%), Positives = 96/250 (38%), Gaps = 59/250 (23%)
Query: 1964 SSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRC 2023
S C+P GD +FS + G C C +T GP CE C F P +
Sbjct: 272 SECRPMQ-KMRGD---VFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAADLQD 326
Query: 2024 DCTPCGTEACDPHSGHC-------LCKAGVTGRRCDRCQEGHFGFDGCGGCRP------- 2069
+ C + +C+ HS C L G++G C+ CQ G C CRP
Sbjct: 327 NA--CRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEG-QHCDRCRPLFYRDPL 383
Query: 2070 -----------CACGP--AAEGSECHPQS--------GQCHCRPGTMGPQCRECAPGYWG 2108
C C P G C S GQC C+ G +C +C P ++G
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
Query: 2109 LPEQ---GCRRCQC------PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVG 2159
L GC+ C C P CD TG+C C ++G C+ C+ V +G
Sbjct: 444 LSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECT------VGYWGLG 497
Query: 2160 HSIH-CEVCD 2168
+ +H C CD
Sbjct: 498 NHLHGCSPCD 507
Score = 69.3 bits (168), Expect = 7e-11
Identities = 47/142 (33%), Positives = 59/142 (41%), Gaps = 12/142 (8%)
Query: 1823 ALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD----RCLPGSG 1878
AL S CLC + G C +C P Y LG C PC C+ C +G
Sbjct: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTG 473
Query: 1879 VCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL 1938
C+ C GAHCE C G+ + C C C + +N C + G QC
Sbjct: 474 QCL-CLSYVTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNV---CSPKNG--QCE 526
Query: 1939 CKPGYAGASCERCAPGFFGNPL 1960
C+P G SC APG+F PL
Sbjct: 527 CRPHVTGRSCSEPAPGYFFAPL 548
Score = 63.2 bits (152), Expect = 5e-09
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 8/132 (6%)
Query: 744 CMCRAHVEGPSC--DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKP 801
C+ A GP C+ +S +G C C +G++G + C GQC CKP
Sbjct: 735 CVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVG--SSCSRLGGQCQCKP 792
Query: 802 HVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
V G+ C C G + L + GC C C G+ C+ TG C C G C
Sbjct: 793 LVVGRCCDRCSTGSYDL---GHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDR 849
Query: 862 PARDHY-LPDLH 872
++ P H
Sbjct: 850 CLAGYFGFPSCH 861
Score = 60.5 bits (145), Expect = 3e-08
Identities = 38/123 (30%), Positives = 47/123 (38%), Gaps = 15/123 (12%)
Query: 1413 PSSSSLFC-RNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRC 1471
P+ + L C R A +L G + C C + C+ GQCPC G+ CS C
Sbjct: 1054 PNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113
Query: 1472 ATGYWGFP--NCRPCDCGAR-----LCDELTGQCICPPRTIPPDCLLCQ-------PQTF 1517
Y+G P C PCDC +CD TG C C C C P
Sbjct: 1114 QENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCL 1173
Query: 1518 GCH 1520
CH
Sbjct: 1174 QCH 1176
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 283 bits (725), Expect = 2e-75
Identities = 159/478 (33%), Positives = 233/478 (48%), Gaps = 65/478 (13%)
Query: 127 WWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQ 186
WWQS G+E V + LDL FH ++++ F RP ++ERS DFG+T+ ++
Sbjct: 111 WWQS---ENGVE--NVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLIERSSDFGKTWGVYR 164
Query: 187 FFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSY 246
+FA DC F + + + D IC + YS I P GE++ ++ + Y
Sbjct: 165 YFAY---DCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPA-FKIEDPY 220
Query: 247 SPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHA 306
SP ++ K TN+R++F++ +TL +L+ + + +YYY++ D+ + G C C+GHA
Sbjct: 221 SPRIQNLLKITNLRIKFVKLHTLGDNLLDSRME---IREKYYYAVYDMVVRGNCFCYGHA 277
Query: 307 DACDAKDPTDPFRLQ--------CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
C P D F + C C+HNT G C+ C ++ PW+PA ++N C+
Sbjct: 278 SECA---PVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK 334
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
CNC H+ C++D V + S GGVC DCQH+T G NCE+C P +Y+ P
Sbjct: 335 CNCNEHSISCHFDMAVYLATGNVS-------GGVCDDCQHNTMGRNCEQCKPFYYQHPER 387
Query: 419 PLDSPHVCRRCNCE--SDFTDGTCEDLT--------GRCYCRPNFSGERCDVCAEGFTGF 468
+ P+ C RC C+ +G C+ T G+C C+ N GE CDVC EGF
Sbjct: 388 DIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
Query: 469 PSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGT--QGNACRKDPRVGRCLCKPNFQGTHC 526
S P S C C+ GT GN C D G C CK G HC
Sbjct: 448 SSEDPFGCKS---------------CACNPLGTIPGGNPC--DSETGHCYCKRLVTGQHC 490
Query: 527 ELCAPGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYF 579
+ C P +G GC+PC C G ++ C ++GQC CR G C+ PGY+
Sbjct: 491 DQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 279 bits (714), Expect = 3e-74
Identities = 259/982 (26%), Positives = 390/982 (39%), Gaps = 152/982 (15%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGA 1890
C C C C PG + C PCQC+GH+D C P +G C++CQ T G
Sbjct: 840 CHCFQGVYARQCDRCLPGHWG------FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGH 893
Query: 1891 HCERCQAGFVSSRDDPSAP-CVSCPCPLSVPSNN-FAEGCVLRGGRTQ--CLCKPGYAGA 1946
+CERC AG+ S C CPCP S FA C Q C+C PGY G+
Sbjct: 894 NCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGS 953
Query: 1947 SCERCAPGFFGNPLVLGSSCQPCDCSGN---GDPNLLFSDCDPLTGACRGCLRHTTGPRC 2003
C+ CA G+FGNP +G SCQPC C N DP CD TG C CL HT G C
Sbjct: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA----CDKETGRCLKCLYHTEGEHC 1009
Query: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTE---------ACDPHSGHCLCKAGVTGRRCDRC 2054
+ C G+YG+A L +C +C C GT CD +G CLC V G+ CDRC
Sbjct: 1010 QFCRFGYYGDA-LQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRC 1068
Query: 2055 QEGHFGFDGCGGCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQG 2113
+ GC PC C A + G C+ +GQC C PG G C EC +WG P+
Sbjct: 1069 APNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVE 1128
Query: 2114 CRRCQC-PGG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCD 2168
CR C C P G +CD TG+C C G+ G RCD C++ + P C C
Sbjct: 1129 CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFP--------DCTPCH 1180
Query: 2169 HCVVL---------------------------------LLDDLERAGALLPAI------H 2189
C L +D +ER + + I
Sbjct: 1181 QCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAA 1240
Query: 2190 EQLRGI-NASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDAR 2248
E L+ I N A + + +A ++ +L + TA++L+ L+ ++ SL +
Sbjct: 1241 EPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVK 1300
Query: 2249 RLGGQAV--------GTRDQASQLL------------AGTEATLGHAKTLLAAIRAVD-- 2286
L Q G D ++ + TE ++ L R D
Sbjct: 1301 ELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVM 1360
Query: 2287 ---------------RTLSELMSQTGHLGLANAS-----APSGEQLLRTLAEVERLLWEM 2326
R L EL + L L+ A+ P G T +
Sbjct: 1361 MERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDE 1420
Query: 2327 RARDLGAPQAAAEAELA--AAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDL 2384
R G P +A A Q+ + Q+ LS+L E Q + +L EA
Sbjct: 1421 GERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEA--KQS 1478
Query: 2385 REALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLL 2444
E + +AT+E +++ N+E Q + L++D+A L + A + L
Sbjct: 1479 AEDILLKTNATKE--KMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVL------- 1529
Query: 2445 HSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSS 2504
K E+ L + +R+++ S L+ A A A+ L + A S
Sbjct: 1530 ------KMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASK 1583
Query: 2505 IILD--VNQDRLTQRAIEASNAYSRILQAV-QAAEDAAG-QALQQADHTWATVVRQGLVD 2560
D V D + + EA A +A+ QA ED G Q L + + + L +
Sbjct: 1584 SATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFN 1643
Query: 2561 RAQQLLANSTALEEAMLQEQQRLG---LVWAALQGARTQLRDVRAKKD-QLEAHIQAAQA 2616
+Q++ +EE + Q G + + + DV+ D +L+ + +
Sbjct: 1644 ASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVEN 1703
Query: 2617 MLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAV 2676
++A T+E++ A+ + EA+ + S+LQ +++ +++ L +D Q +
Sbjct: 1704 LIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYEDNQRYL--EDKAQEL 1761
Query: 2677 LDAGHSVSTLEKTLPQLLAKLS 2698
V +L K + Q +A S
Sbjct: 1762 ARLEGEVRSLLKDISQKVAVYS 1783
Score = 240 bits (613), Expect = 2e-62
Identities = 139/409 (33%), Positives = 189/409 (46%), Gaps = 48/409 (11%)
Query: 494 CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGVAD 550
C+C G+ + C DP G+C C+PN G C CAPG +G GC+PC+C G +
Sbjct: 773 CECDPQGSLSSVC--DPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 551 DRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDE-AGRCL-CQ 608
C+P TGQC C G CDRC PG++ FP CQ C C+ + CD G CL CQ
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHA---DDCDPVTGECLNCQ 887
Query: 609 PEFAGPHCDRCRPGYHGFP------NCQACTC----DPRGALDQLCGAGGL-----CRCR 653
G +C+RC GY+G P +C+ C C D + C + C C
Sbjct: 888 DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
Query: 654 PGYTGTACQECSPGFHGFP-----SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVTGL 705
PGY G+ C +C+ G+ G P SC PC C + + + ACD +G+C C G
Sbjct: 948 PGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGE 1007
Query: 706 RCDTCVPGAYNFPY---CEAGSCHPAGLAP-----VDPALPEAQVPCMCRAHVEGPSCDR 757
C C G Y C C+ G D +A C+C +V G +CDR
Sbjct: 1008 HCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR 1067
Query: 758 CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFG 817
C P W L+ GC C+C+ + G C TGQC C P G+ C+ C++ F+G
Sbjct: 1068 CAPNTWQLASGT--GCDPCNCNAAHSFG--PSCNEFTGQCQCMPGFGGRTCSECQELFWG 1123
Query: 818 LDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
+ CR+C CD G C+ TG C C +GP C + R +
Sbjct: 1124 DPDVE---CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY 1169
Score = 234 bits (596), Expect = 2e-60
Identities = 214/827 (25%), Positives = 306/827 (37%), Gaps = 188/827 (22%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGAR--------------- 1489
G C C + G +C C Y P C+ C+C
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 1490 -----LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVG------CEECNCSGPGIQE- 1537
+CD+ C T+ +C C+P + HP CE C C G Q
Sbjct: 356 NVSGGVCDD------CQHNTMGRNCEQCKPFYYQ-HPERDIRDPNFCERCTCDPAGSQNE 408
Query: 1538 -----LTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPG 1587
TD + +GQC+C+ NV G CD C GF+ C+ C C+ GT PG
Sbjct: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPG 468
Query: 1588 --VCDPLTGQCYCKENVQGPKCDQCSLGTFSL----DAANPKGC-------TRCFCFGAT 1634
CD TG CYCK V G CDQC + L D P C CF
Sbjct: 469 GNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQ 528
Query: 1635 ERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQ---PGTEMLRADLRHVPEAVPEAFPE 1691
CR RQ G+ + D + E PG ++ + +++ + +P
Sbjct: 529 CSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIV--ERQYIQDRIPSWTGA 586
Query: 1692 LYWQAPP-SYLGDRVSSYGGTLRYEL--HSETQRGDVF------------VPMESRPDVV 1736
+ + P +YL + + ++ Y++ E Q D + +P SR
Sbjct: 587 GFVRVPEGAYLEFFIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNT 646
Query: 1737 LQGNQMSITFLEPA-----YPTPGHVHRGQLQLVEGNFRHTETRNTVSREELMMVLASLE 1791
+ + + L P P P +G N R EL +S
Sbjct: 647 IPDDDNQVVSLSPGSRYVVLPRPVCFEKGT--------------NYTVRLELPQYTSS-- 690
Query: 1792 QLQIRALFSQISSAVFL---RRVALEVASPAGQGALASNV----ELCLCPASYRG----- 1839
+ + ++ I S V + + + + +G G + ++ + C + R
Sbjct: 691 DSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTP 750
Query: 1840 --DSCQECAPGFYRDVKGLFLGRCVPCQCHGH---SDRCLPGSGVCVDCQHNTEGAHCER 1894
D C+ + L + C+C S C P G C C+ N G C R
Sbjct: 751 MTDVCRN----IIFSISALLHQTGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNR 805
Query: 1895 CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPG 1954
C G PS C C C L N F QC C G C+RC PG
Sbjct: 806 CAPGTFGF--GPSG-CKPCECHLQGSVNAFCNPVT-----GQCHCFQGVYARQCDRCLPG 857
Query: 1955 FFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNA 2014
+G P SCQPC C+G+ D DCDP+TG C C +T G CE C G+YG+
Sbjct: 858 HWGFP-----SCQPCQCNGHAD------DCDPVTGECLNCQDYTMGHNCERCLAGYYGDP 906
Query: 2015 LLPGNCTRCDCTPCGTEACDPHSGH----------------CLCKAGVTGRRCDRCQEGH 2058
++ G+ C PC P SG C+C G G RCD C G+
Sbjct: 907 II-GSGDHCRPCPCPD---GPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGY 962
Query: 2059 FG--FDGCGGCRPCACG---PAAEGSECHPQSGQC-HCRPGTMGPQCRECAPGYWG-LPE 2111
FG + G C+PC C + C ++G+C C T G C+ C GY+G +
Sbjct: 963 FGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQ 1022
Query: 2112 QGCRRCQC------------PGGRCDPHTGRCNCPPGLSGERCDTCS 2146
Q CR+C C +CD TG+C C P + G+ CD C+
Sbjct: 1023 QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCA 1069
Score = 215 bits (547), Expect = 7e-55
Identities = 141/410 (34%), Positives = 175/410 (42%), Gaps = 81/410 (19%)
Query: 300 CVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
C CH G +A +P QC C CDRC PG P CQ
Sbjct: 821 CECHLQGSVNAF-----CNPVTGQCHCFQGVYARQCDRCLPGHWGFP----------SCQ 865
Query: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
C C GHA DC DP G C++CQ +T G NCERCL G+Y P
Sbjct: 866 PCQCNGHADDC--DPVT----------------GECLNCQDYTMGHNCERCLAGYYGDP- 906
Query: 418 HPLDSPHVCRRCNCES------DFTDGTCED---LTGRCYCRPNFSGERCDVCAEGFTGF 468
+ S CR C C F +D L C C P + G RCD CA G+ G
Sbjct: 907 -IIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGN 965
Query: 469 PSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCE 527
PS +V + Q C + T AC D GRCL C + +G HC+
Sbjct: 966 PS-------------EVGGSCQPCQCHNNIDTTDPEAC--DKETGRCLKCLYHTEGEHCQ 1010
Query: 528 LCAPGFYGPG----CQPCQCSSPGV-------ADDRCDPDTGQCRCRVGFEGATCDRCAP 576
C G+YG C+ C C+ G +D +CD TGQC C G CDRCAP
Sbjct: 1011 FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAP 1070
Query: 577 GYFHFPL---CQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYHGFPN--CQ 630
+ C C C+ A + C+E G+C C P F G C C+ + G P+ C+
Sbjct: 1071 NTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECR 1130
Query: 631 ACTCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHG-FPSCVPCH 678
AC CDPRG C + G C C G G C +C+ G+ G FP C PCH
Sbjct: 1131 ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCH 1180
Score = 201 bits (510), Expect = 1e-50
Identities = 145/454 (31%), Positives = 188/454 (41%), Gaps = 97/454 (21%)
Query: 429 CNCESDFT-DGTCEDLTGRCYCRPNFSGERCDVCAEGFTGF-PS-CYPTPSSSNDTREQV 485
C C+ + C+ G+C CRPN G C+ CA G GF PS C P
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKP------------ 820
Query: 486 LPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG-PGCQPCQCS 544
C+C G+ C +P G+C C C+ C PG +G P CQPCQC+
Sbjct: 821 --------CECHLQGSVNAFC--NPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCN 870
Query: 545 SPGVADDRCDPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCSPAGTLPE 597
G ADD CDP TG+C C+ G C+RC GY+ P+ C+ C C P+
Sbjct: 871 --GHADD-CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPC------PD 921
Query: 598 GCDEAGR----------------CLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC-- 634
G D +GR C+C P + G CD C GY G P +CQ C C
Sbjct: 922 GPD-SGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
Query: 635 -----DPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHG---FPSCVPCHCSAEGSLH 686
DP A D+ G +C G CQ C G++G C C C+ G++
Sbjct: 981 NIDTTDPE-ACDK--ETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQ 1037
Query: 687 -------AACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPY---CEAGSCHPAGLAPVDPA 736
CD +GQC C P V G CD C P + C+ +C+ A P+
Sbjct: 1038 EHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAA--HSFGPS 1095
Query: 737 LPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPE-GCTRCSCDLRGTLGGVAECQPGTG 795
E C C G +C C+ FWG +P+ C C CD RG +C TG
Sbjct: 1096 CNEFTGQCQCMPGFGGRTCSECQELFWG----DPDVECRACDCDPRGI--ETPQCDQSTG 1149
Query: 796 QCFCKPHVCGQACASCKDGFFGLDQADYFGCRSC 829
QC C V G C C G+ G+ D C C
Sbjct: 1150 QCVCVEGVEGPRCDKCTRGYSGV-FPDCTPCHQC 1182
Score = 160 bits (405), Expect = 2e-38
Identities = 98/303 (32%), Positives = 129/303 (42%), Gaps = 44/303 (14%)
Query: 603 GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
G C+C+ G +C+ C YH P R G AC+
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLP----------------------WRPAEGRNSNACK 333
Query: 663 ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCS-CRPRVTGLRCDTCVPGAYNFP--- 718
+C+ H + CH L A + G C C+ G C+ C P Y P
Sbjct: 334 KCNCNEHS----ISCHFDMAVYL-ATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
Query: 719 -----YCEAGSCHPAGL-------APVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLS 766
+CE +C PAG + D + C C+ +VEG CD CK GF+ LS
Sbjct: 389 IRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLS 448
Query: 767 PSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGC 826
+P GC C+C+ GT+ G C TG C+CK V GQ C C +GL D GC
Sbjct: 449 SEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSN-DLDGC 507
Query: 827 RSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHLRLELEEAATPEG 886
R C CD+GGAL SC +G C CRP+ G C+E +Y L H E EEA G
Sbjct: 508 RPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPG 567
Query: 887 HAV 889
++
Sbjct: 568 VSI 570
Score = 148 bits (374), Expect = 9e-35
Identities = 94/281 (33%), Positives = 124/281 (44%), Gaps = 40/281 (14%)
Query: 1864 CQCHGHSDRCLPGSGVCVD----------CQHNTEGAHCERCQAGFVSSRDDP-----SA 1908
C C+GH+ C P G + C+HNT+G +CE C + P S
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSN 330
Query: 1909 PCVSCPCPLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFFGNP---LV 1961
C C C S +F L G C C+ G +CE+C P ++ +P +
Sbjct: 331 ACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIR 390
Query: 1962 LGSSCQPCDCSGNGDPNLLFSDCDPLT--------GACRGCLRHTTGPRCEICAPGFYG- 2012
+ C+ C C G N CD T G CR C + G C++C GFY
Sbjct: 391 DPNFCERCTCDPAGSQNE--GICDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGFYDL 447
Query: 2013 NALLPGNCTRCDCTPCGT----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDG-CGGC 2067
++ P C C C P GT CD +GHC CK VTG+ CD+C H+G GC
Sbjct: 448 SSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC 507
Query: 2068 RPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW 2107
RPC C A + C +SGQC CRP +G QC E PGY+
Sbjct: 508 RPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 145 bits (366), Expect = 7e-34
Identities = 80/231 (34%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP 1479
C A F +G +PC CH G+ C P GQC C V R C RC G+WGFP
Sbjct: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP 862
Query: 1480 NCRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNC-S 1531
+C+PC C CD +TG+C+ C T+ +C C +G P++G C C C
Sbjct: 863 SCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYG-DPIIGSGDHCRPCPCPD 921
Query: 1532 GPGIQELTDPTCDTD----SGQCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHE- 1581
GP +C D C C P G RCD C+ G+ G P C+PC CH
Sbjct: 922 GPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNN 981
Query: 1582 -AGTAPGVCDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
T P CD TG+C C + +G C C G + A + C +C C
Sbjct: 982 IDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYG--DALQQDCRKCVC 1030
Score = 141 bits (356), Expect = 1e-32
Identities = 78/214 (36%), Positives = 101/214 (47%), Gaps = 24/214 (11%)
Query: 1436 RPCGCHE-VGATGP-TCEPFGGQC-PCHAHVIGRDCSRCATGYWGFP---NCRPCDCGAR 1489
+PC CH + T P C+ G+C C H G C C GY+G +CR C C
Sbjct: 974 QPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYL 1033
Query: 1490 ------------LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQE 1537
CD+ TGQC+C P I +C C P T+ GC+ CNC+
Sbjct: 1034 GTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAA---H 1090
Query: 1538 LTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPGVCDPLTGQ 1595
P+C+ +GQC+C P GR C C F G P CR CDC G CD TGQ
Sbjct: 1091 SFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQ 1150
Query: 1596 CYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCF 1629
C C E V+GP+CD+C+ G +S + C +CF
Sbjct: 1151 CVCVEGVEGPRCDKCTRG-YSGVFPDCTPCHQCF 1183
Score = 132 bits (333), Expect = 5e-30
Identities = 84/242 (34%), Positives = 113/242 (46%), Gaps = 24/242 (9%)
Query: 1941 PGYAGASCERCAPGFFGNPLVLGSSCQPCDC---SGNGDPNLLFSDCDPLTGACRGCLRH 1997
P Y + + +P + LVL C+ D G+GD + S + T CL +
Sbjct: 685 PQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWE--TFQRYRCLEN 742
Query: 1998 TTG----PRCEICAPGFYG-NALLPGNCTRCDCTPCGT--EACDPHSGHCLCKAGVTGRR 2050
+ P ++C + +ALL C+C P G+ CDP+ G C C+ V GR
Sbjct: 743 SRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRT 802
Query: 2051 CDRCQEGHFGFDGCGGCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGL 2109
C+RC G FGF G GC+PC C + + C+P +GQCHC G QC C PG+WG
Sbjct: 803 CNRCAPGTFGF-GPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF 861
Query: 2110 PEQGCRRCQCPG--GRCDPHTGRC-NCPPGLSGERCDTCSQQHQVPVPGGP-VGHSIHCE 2165
P C+ CQC G CDP TG C NC G C+ C + G P +G HC
Sbjct: 862 P--SCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYY----GDPIIGSGDHCR 915
Query: 2166 VC 2167
C
Sbjct: 916 PC 917
Score = 132 bits (332), Expect = 6e-30
Identities = 86/266 (32%), Positives = 116/266 (43%), Gaps = 54/266 (20%)
Query: 445 GRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGN 504
G C CR N G C++C + + P +SN ++ C+C+
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKK----------CNCNEHSI--- 342
Query: 505 ACRKDPRV---------GRCL-CKPNFQGTHCELCAPGFY--------GPG-CQPCQCS- 544
+C D V G C C+ N G +CE C P +Y P C+ C C
Sbjct: 343 SCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDP 402
Query: 545 ----SPGVADDRCDPDTG----QCRCRVGFEGATCDRCAPGYFHFPL-----CQLCGCSP 591
+ G+ D D TG QCRC++ EG CD C G++ C+ C C+P
Sbjct: 403 AGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNP 462
Query: 592 AGTLPEG--CD-EAGRCLCQPEFAGPHCDRCRPGYHGFPN----CQACTCDPRGALDQLC 644
GT+P G CD E G C C+ G HCD+C P + G N C+ C CD GAL+ C
Sbjct: 463 LGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSC 522
Query: 645 GA-GGLCRCRPGYTGTACQECSPGFH 669
A G C CRP G C E PG++
Sbjct: 523 FAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 131 bits (330), Expect = 1e-29
Identities = 76/234 (32%), Positives = 103/234 (44%), Gaps = 33/234 (14%)
Query: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF- 1478
CRN S+S + C C G+ C+P GGQC C +V+GR C+RCA G +GF
Sbjct: 755 CRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFG 814
Query: 1479 -PNCRPCDCGAR-----LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSG 1532
C+PC+C + C+ +TGQC C C C P +G C+ C C+G
Sbjct: 815 PSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWG---FPSCQPCQCNG 871
Query: 1533 PGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHGYP------RCRPCDCHEAGTA 1585
CD +G+C C+ G C+ C G++G P CRPC C + G
Sbjct: 872 HA------DDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPD-GPD 924
Query: 1586 PG-------VCDPLTGQ--CYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
G DP+T Q C C G +CD C+ G F + C C C
Sbjct: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC 978
Score = 94.4 bits (233), Expect = 2e-18
Identities = 63/224 (28%), Positives = 91/224 (40%), Gaps = 44/224 (19%)
Query: 1432 NNGARPCGCHEVG-----------ATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWGFP 1479
+N + C C+E ATG GG C C + +GR+C +C Y+ P
Sbjct: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVS---GGVCDDCQHNTMGRNCEQCKPFYYQHP 385
Query: 1480 N--------CRPCDCGAR------LCDELT--------GQCICPPRTIPPDCLLCQPQTF 1517
C C C +CD T GQC C C +C+ +
Sbjct: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
Query: 1518 --GCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-- 1573
GC+ C C+ G +P CD+++G C C+ VTG+ CD C P G
Sbjct: 446 DLSSEDPFGCKSCACNPLGTIPGGNP-CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
Query: 1574 --CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1615
CRPCDC G C +GQC C+ ++ G +C++ G +
Sbjct: 505 DGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 85.1 bits (209), Expect = 1e-15
Identities = 60/207 (28%), Positives = 80/207 (38%), Gaps = 46/207 (22%)
Query: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELT-GQCICPPRTIPPDCLLCQ 1513
G C C+ H C P D + + G C+C T +C LC
Sbjct: 269 GNCFCYGHA---------------SECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCM 313
Query: 1514 P--QTFGCHPLVG-----CEECNCSGPGIQELTD-----PTCDTDSGQCK-CRPNVTGRR 1560
P G C++CNC+ I D T + G C C+ N GR
Sbjct: 314 DFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRN 373
Query: 1561 CDTCSPGFHGYPR--------CRPCDCHEAGTA-PGVCDPLT--------GQCYCKENVQ 1603
C+ C P ++ +P C C C AG+ G+CD T GQC CK NV+
Sbjct: 374 CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVE 433
Query: 1604 GPKCDQCSLGTFSLDAANPKGCTRCFC 1630
G CD C G + L + +P GC C C
Sbjct: 434 GEHCDVCKEGFYDLSSEDPFGCKSCAC 460
Score = 81.6 bits (200), Expect = 1e-14
Identities = 64/237 (27%), Positives = 87/237 (36%), Gaps = 66/237 (27%)
Query: 1969 CDCSGNGDPNLLFSDCDPLTGACRG----------CLRHTTGPRCEICAPGFYGNALLPG 2018
C C G+ S+C P+ G C +T G CE+C ++ P
Sbjct: 271 CFCYGHA------SECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPA 324
Query: 2019 NCTRCD-CTPCGTEACDPHSGHC-------LCKAGVTGRRCDRCQEGHFGFDGCGGCRP- 2069
+ C C C+ HS C L V+G CD CQ G + C C+P
Sbjct: 325 EGRNSNACKKCN---CNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRN-CEQCKPF 380
Query: 2070 -----------------CACGPAAEGSE--CHPQS--------GQCHCRPGTMGPQCREC 2102
C C PA +E C + GQC C+ G C C
Sbjct: 381 YYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVC 440
Query: 2103 APGYWGLPEQ---GCRRCQC------PGGR-CDPHTGRCNCPPGLSGERCDTCSQQH 2149
G++ L + GC+ C C PGG CD TG C C ++G+ CD C +H
Sbjct: 441 KEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEH 497
Score = 80.9 bits (198), Expect = 2e-14
Identities = 43/116 (37%), Positives = 52/116 (44%), Gaps = 8/116 (6%)
Query: 1421 RNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN 1480
R A + L G PC C+ + GP+C F GQC C GR CS C +WG P+
Sbjct: 1067 RCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPD 1126
Query: 1481 --CRPCDCGAR-----LCDELTGQCICPPRTIPPDCLLCQPQTFGCHP-LVGCEEC 1528
CR CDC R CD+ TGQC+C P C C G P C +C
Sbjct: 1127 VECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQC 1182
Score = 79.0 bits (193), Expect = 8e-14
Identities = 39/121 (32%), Positives = 56/121 (46%), Gaps = 5/121 (4%)
Query: 747 RAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQ 806
R+ V+ P D C+ + +S + C CD +G+L V C P GQC C+P+V G+
Sbjct: 744 RSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSV--CDPNGGQCQCRPNVVGR 801
Query: 807 ACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
C C G FG + GC+ C C + G++ C P TG C C C H
Sbjct: 802 TCNRCAPGTFGFGPS---GCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
Query: 867 Y 867
+
Sbjct: 859 W 859
Score = 32.3 bits (72), Expect = 8.9
Identities = 22/65 (33%), Positives = 24/65 (36%), Gaps = 14/65 (21%)
Query: 1488 ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDS 1547
ARL DEL G + D T G P C E C GP C TD
Sbjct: 1375 ARLLDELAG------KLQSLDLSAAAEMTCGTPPGASCSETECGGPN--------CRTDE 1420
Query: 1548 GQCKC 1552
G+ KC
Sbjct: 1421 GERKC 1425
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 254 bits (650), Expect = 8e-67
Identities = 149/427 (34%), Positives = 223/427 (52%), Gaps = 46/427 (10%)
Query: 47 PPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDIC 106
P + N A G + S+TCG PAR YC V + +R C +C
Sbjct: 53 PDFVNAAFGKDVRVSSTCGRP-PAR---------YC------VVSERGEERLRS--CHLC 94
Query: 107 TAANSNKAHPASNAIDGTE----RWWQSPPLSRGLEY-NEVNVTLDLGQVFHVAYVLIKF 161
A++ KAHP + D WQS L++ + V +TL LG+ F V YV ++F
Sbjct: 95 NASDPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNVTLTLSLGKKFEVTYVSLQF 151
Query: 162 ANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSR 221
SPRP+ + +SMD+GRT+ P+QF+++ R R + + + A+CT ++
Sbjct: 152 C-SPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITK-QNEQEAVCTDSHTD 209
Query: 222 IVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDP 281
+ PL G I S ++GRP A +F SP+L+++ AT++R+ F R H G D
Sbjct: 210 MRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----HTFGDENEDD 264
Query: 282 TVTRR--YYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPG 339
+ R Y+Y++ D+ +GGRC C+GHA C +D D L C C+HNT G CDRC P
Sbjct: 265 SELARDSYFYAVSDLQVGGRCKCNGHAARC-VRDRDDS--LVCDCRHNTAGPECDRCKPF 321
Query: 340 FNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHH 399
+PW+ ATA ANEC +CNC HA C ++ E+ + +S GGVC++C+H+
Sbjct: 322 HYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKS-------GGVCLNCRHN 374
Query: 400 TTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDG-TCEDLTGRCYCRPNFSGERC 458
T G +C C G+YR P+ C+ C+C G TC TG+C C+ +G C
Sbjct: 375 TAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITC 434
Query: 459 DVCAEGF 465
+ CA+G+
Sbjct: 435 NRCAKGY 441
Score = 81.3 bits (199), Expect = 2e-14
Identities = 60/199 (30%), Positives = 82/199 (41%), Gaps = 23/199 (11%)
Query: 1864 CQCHGHSDRCL---PGSGVCVDCQHNTEGAHCERCQ-----AGFVSSRDDPSAPCVSCPC 1915
C+C+GH+ RC+ S VC DC+HNT G C+RC+ + + + CV+C C
Sbjct: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
Query: 1916 PLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFF---GNPLVLGSSCQP 1968
L F GR CL C+ AG C C G++ G P+ +C+
Sbjct: 344 NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKA 403
Query: 1969 CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPC 2028
CDC G C+ TG C C TG C CA G+ + C + P
Sbjct: 404 CDCHPVGAAG---KTCNQTTGQC-PCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPP 459
Query: 2029 GTEAC---DPHSGHCLCKA 2044
T A +P CKA
Sbjct: 460 TTAASSVEEPEDCDSYCKA 478
Score = 79.7 bits (195), Expect = 5e-14
Identities = 50/151 (33%), Positives = 62/151 (41%), Gaps = 32/151 (21%)
Query: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
C CR N +G CD C P Y P RE A + V C+C+ C
Sbjct: 304 CDCRHNTAGPECDRCK------PFHYDRPWQRATARE----ANECVACNCNL---HARRC 350
Query: 507 RKDPRV---------GRCL-CKPNFQGTHCELCAPGFYGP---------GCQPCQCSSPG 547
R + + G CL C+ N G HC C G+Y C+ C C G
Sbjct: 351 RFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVG 410
Query: 548 VADDRCDPDTGQCRCRVGFEGATCDRCAPGY 578
A C+ TGQC C+ G G TC+RCA GY
Sbjct: 411 AAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 78.6 bits (192), Expect = 1e-13
Identities = 52/178 (29%), Positives = 75/178 (42%), Gaps = 29/178 (16%)
Query: 600 DEAGRCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA-------LDQ 642
D++ C C+ AGP CDRC+P ++ P C AC C+ L +
Sbjct: 299 DDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYK 358
Query: 643 LCG--AGGLC-RCRPGYTGTACQECSPGFH---GFP-----SCVPCHCSAEGSLHAACDP 691
L G +GG+C CR G C C G++ G P +C C C G+ C+
Sbjct: 359 LSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQ 418
Query: 692 RSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAH 749
+GQC C+ VTG+ C+ C G Y C +AP A + P C ++
Sbjct: 419 TTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSY 475
Score = 77.8 bits (190), Expect = 2e-13
Identities = 58/199 (29%), Positives = 76/199 (38%), Gaps = 33/199 (16%)
Query: 1830 LCLCPASYRGDSCQECAPGFY----RDVKGLFLGRCVPCQCHGHSDRC--------LPG- 1876
+C C + G C C P Y + CV C C+ H+ RC L G
Sbjct: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
Query: 1877 --SGVCVDCQHNTEGAHCERCQAGFVSSRDDP---SAPCVSCPCPLSVPSNNFAEGCVLR 1931
GVC++C+HNT G HC C+ G+ P C +C C P + C
Sbjct: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCH---PVGAAGKTCNQT 419
Query: 1932 GGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFS------DCD 1985
G QC CK G G +C RCA G+ + S PC P S DCD
Sbjct: 420 TG--QCPCKDGVTGITCNRCAKGYQQS----RSPIAPCIKIPVAPPTTAASSVEEPEDCD 473
Query: 1986 PLTGACRGCLRHTTGPRCE 2004
A +G L+ C+
Sbjct: 474 SYCKASKGKLKINMKKYCK 492
Score = 75.9 bits (185), Expect = 7e-13
Identities = 56/181 (30%), Positives = 72/181 (39%), Gaps = 43/181 (23%)
Query: 1454 GGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513
GG+C C+ H +RC R D D L C C T P+C C+
Sbjct: 282 GGRCKCNGHA-----ARCV---------RDRD------DSLV--CDCRHNTAGPECDRCK 319
Query: 1514 P-------QTFGCHPLVGCEECNCSGPGIQ-----ELTDPTCDTDSGQC-KCRPNVTGRR 1560
P Q C CNC+ + EL + G C CR N GR
Sbjct: 320 PFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRH 379
Query: 1561 CDTCSPGFH---GYP-----RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
C C G++ G P C+ CDCH G A C+ TGQC CK+ V G C++C+
Sbjct: 380 CHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAK 439
Query: 1613 G 1613
G
Sbjct: 440 G 440
Score = 73.9 bits (180), Expect = 3e-12
Identities = 51/167 (30%), Positives = 66/167 (39%), Gaps = 30/167 (17%)
Query: 541 CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL----------CQLCGCS 590
C+C+ R D+ C CR G CDRC P ++ P C C C+
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 591 PAGT---------LPEGCDEAGRCL-CQPEFAGPHCDRCRPGYH---GFP-----NCQAC 632
G G CL C+ AG HC C+ GY+ G P C+AC
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
Query: 633 TCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFPSCV-PC 677
C P GA + C G C C+ G TG C C+ G+ S + PC
Sbjct: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPC 451
Score = 70.9 bits (172), Expect = 2e-11
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 23/142 (16%)
Query: 744 CMCRAHVEGPSCDRCKPGFWG-----LSPSNPEGCTRCSCDLRGT----------LGGVA 788
C CR + GP CDRCKP + + C C+C+L L G
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG-- 361
Query: 789 ECQPGTGQCF-CKPHVCGQACASCKDGFF---GLDQADYFGCRSCRCDIGGALGQSCEPR 844
+ G C C+ + G+ C CK+G++ G C++C C GA G++C
Sbjct: 362 --RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQT 419
Query: 845 TGVCRCRPNTQGPTCSEPARDH 866
TG C C+ G TC+ A+ +
Sbjct: 420 TGQCPCKDGVTGITCNRCAKGY 441
Score = 69.7 bits (169), Expect = 5e-11
Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 29/162 (17%)
Query: 1969 CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY------GNALLPGNCTR 2022
C C+G+ + D D L CR +T GP C+ C P Y A C
Sbjct: 285 CKCNGHAARCVRDRD-DSLVCDCR---HNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
Query: 2023 CDCTPCGTEACD-----------PHSGHCL-CKAGVTGRRCDRCQEGHFGFDGCG----- 2065
C+C C G CL C+ GR C C+EG++ G
Sbjct: 341 CNCN-LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
Query: 2066 GCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGY 2106
C+ C C P A G C+ +GQC C+ G G C CA GY
Sbjct: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 61.2 bits (147), Expect = 2e-08
Identities = 42/163 (25%), Positives = 61/163 (37%), Gaps = 52/163 (31%)
Query: 2033 CDPHSGHCL----------CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSEC- 2081
C+ H+ C+ C+ G CDRC+ H+ RP A E +EC
Sbjct: 287 CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYD-------RPWQRATAREANECV 339
Query: 2082 ----------------------HPQSGQC-HCRPGTMGPQCRECAPGYW---GLP---EQ 2112
G C +CR T G C C GY+ G P +
Sbjct: 340 ACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
Query: 2113 GCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQ 2150
C+ C C G C+ TG+C C G++G C+ C++ +Q
Sbjct: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQ 442
Score = 55.1 bits (131), Expect = 1e-06
Identities = 22/45 (48%), Positives = 25/45 (55%)
Query: 1431 YNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGY 1475
+ + C CH VGA G TC GQCPC V G C+RCA GY
Sbjct: 397 HRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 52.8 bits (125), Expect = 6e-06
Identities = 47/178 (26%), Positives = 64/178 (35%), Gaps = 39/178 (21%)
Query: 1457 CPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCG--ARLCDELTGQCICPPRT 1504
C C + G +C RC ++ P C C+C AR C R
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 1505 IPPDCLLCQPQTFG--CH------------PLV---GCEECNCSGPGIQELTDPTCDTDS 1547
CL C+ T G CH P+ C+ C+C G TC+ +
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA---AGKTCNQTT 420
Query: 1548 GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAP------GVCDPLTGQCYCK 1599
GQC C+ VTG C+ C+ G+ R C + AP V +P YCK
Sbjct: 421 GQCPCKDGVTGITCNRCAKGYQ-QSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCK 477
Score = 33.9 bits (76), Expect = 3.1
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 15/79 (18%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQ----------PWKPAT 349
C CH A + T QC C+ G TC+RC G+ Q P P T
Sbjct: 404 CDCHPVGAAGKTCNQTTG---QCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPT 460
Query: 350 --ANSANECQSCNCYGHAT 366
A+S E + C+ Y A+
Sbjct: 461 TAASSVEEPEDCDSYCKAS 479
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 236 bits (601), Expect = 4e-61
Identities = 146/445 (32%), Positives = 212/445 (47%), Gaps = 60/445 (13%)
Query: 46 HPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDI 105
+P NLA G ++ A TCG+ A +LYC + + T R CD
Sbjct: 35 NPRMGNLALGRKLWADTTCGQNAT---------ELYC------FYSENTDLTCRQPKCDK 79
Query: 106 CTAANSNKAHPASNAIDGTER----WWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKF 161
C AA + AH S D + R WWQS + + + LDL F+ ++++ F
Sbjct: 80 CNAAYPHLAHLPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLIVMF 134
Query: 162 ANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSR 221
SPRP VL+RS DFG+T++P+++FA++ C FG LE AICT++YS
Sbjct: 135 -KSPRPAAMVLDRSQDFGKTWKPYKYFATN---CSATFG---LEDDVVKKGAICTSKYSS 187
Query: 222 IVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDP 281
P GE++ ++ N YS ++E K TN+R++ L+ +
Sbjct: 188 PFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQ 246
Query: 282 TVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRL---------QCTCQHNTCGGT 332
T +Y+I D + G C C+GHAD C P + +C C+HNT G
Sbjct: 247 HFT---HYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSH 303
Query: 333 CDRCCPGFNQQPWKPATANSA--NECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGG 390
C C P +N +PW+ A + NEC++C C GHA C++D V ++S G
Sbjct: 304 CQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRS-------G 356
Query: 391 GVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE-------SDFTDGTCEDL 443
GVC DCQH+T G C+RC PGFYR P +P C+ C+C + C+
Sbjct: 357 GVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPS 416
Query: 444 TGRCYCRPNFSGERCDVCAEGFTGF 468
G C C+P +G RCD C G+ GF
Sbjct: 417 NGDCPCKPGVAGRRCDRCMVGYWGF 441
Score = 117 bits (292), Expect = 3e-25
Identities = 63/177 (35%), Positives = 83/177 (46%), Gaps = 30/177 (16%)
Query: 1936 QCLCKPGYAGASCERCAPGFFGNPLVLG-------SSCQPCDCSGNGDP-----NLLFSD 1983
+C+CK AG+ C+ CAP + P + C+ C C+G+ D N+ +
Sbjct: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEAS 351
Query: 1984 CDPLTGACRGCLRHTTGPRCEICAPGFYGNA----LLPGNCTRCDCTPCGTEA------- 2032
+ G C C +T G C+ C PGFY + P C C C P G+
Sbjct: 352 GNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVT 411
Query: 2033 -CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQC 2088
CDP +G C CK GV GRRCDRC G++GF G GCRPC C C P +G C
Sbjct: 412 FCDPSNGDCPCKPGVAGRRCDRCMVGYWGF-GDYGCRPCDC-----AGSCDPITGDC 462
Score = 112 bits (281), Expect = 5e-24
Identities = 67/185 (36%), Positives = 84/185 (45%), Gaps = 39/185 (21%)
Query: 1831 CLCPASYRGDSCQECAPGFY------RDVKGLFLGRCVPCQCHGHSDRCL---------- 1874
C+C + G CQ CAP + D K C C+C+GH+D C
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
Query: 1875 -PGSGVCVDCQHNTEGAHCERCQAGFVS------SRDDPSAPCVSCPCPLSVPSNNFAEG 1927
GVC DCQHNTEG +C+RC+ GF S D PC P +V N
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 1928 CVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGS-SCQPCDCSGNGDPNLLFSDCDP 1986
C G C CKPG AG C+RC G++G G C+PCDC+G+ CDP
Sbjct: 413 CDPSNG--DCPCKPGVAGRRCDRCMVGYWG----FGDYGCRPCDCAGS---------CDP 457
Query: 1987 LTGAC 1991
+TG C
Sbjct: 458 ITGDC 462
Score = 99.8 bits (247), Expect = 5e-20
Identities = 61/203 (30%), Positives = 79/203 (38%), Gaps = 42/203 (20%)
Query: 1969 CDCSGNGDPNLLFSDCDPLT---------GACRGCLRHTTGPRCEICAPGFY-------- 2011
C C+G+ D + P+ G C C +T G C+ CAP +
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 2012 GNALLPGNCTRCDCTPCGT---------EACDPHSGHCL--CKAGVTGRRCDRCQEGHFG 2060
G P C C C EA SG C+ G+ C RC+ G +
Sbjct: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
Query: 2061 -----FDGCGGCRPCACGPAAEG-------SECHPQSGQCHCRPGTMGPQCRECAPGYWG 2108
F C+PC+C P + C P +G C C+PG G +C C GYWG
Sbjct: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG 440
Query: 2109 LPEQGCRRCQCPGGRCDPHTGRC 2131
+ GCR C C G CDP TG C
Sbjct: 441 FGDYGCRPCDC-AGSCDPITGDC 462
Score = 92.0 bits (227), Expect = 1e-17
Identities = 74/253 (29%), Positives = 101/253 (39%), Gaps = 57/253 (22%)
Query: 603 GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
G C C H D+C P HGF +A G + G C C+ G+ CQ
Sbjct: 260 GSCFCNG-----HADQCIP-VHGFRPVKA-----PGTFHMVHGK---CMCKHNTAGSHCQ 305
Query: 663 ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEA 722
C+P ++ P +A+G A + R+ +C+ DTC ++ EA
Sbjct: 306 HCAPLYNDRP-----WEAADGKTGAPNECRTCKCNGH-------ADTC---HFDVNVWEA 350
Query: 723 GSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWG---LSPSNPEGCTRCSCD 779
G+ C+ + EG C RCKPGF+ S P+ C CSC
Sbjct: 351 SGNRSGGVCDD------------CQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCH 398
Query: 780 LRGTL----GGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGG 835
G+ V C P G C CKP V G+ C C G++G +GCR C C
Sbjct: 399 PVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGD---YGCRPCDC---- 451
Query: 836 ALGQSCEPRTGVC 848
SC+P TG C
Sbjct: 452 --AGSCDPITGDC 462
Score = 90.5 bits (223), Expect = 3e-17
Identities = 67/232 (28%), Positives = 90/232 (38%), Gaps = 59/232 (25%)
Query: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
SC C GHA C V R ++ + G C+ C+H+T G +C+ C P + P
Sbjct: 261 SCFCNGHADQCI---PVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPW 316
Query: 418 HPLD----SPHVCRRCNCES----------------DFTDGTCEDLTGRCYCRPNFSGER 457
D +P+ CR C C + + G C+D C+ N G+
Sbjct: 317 EAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQY 370
Query: 458 CDVCAEGF---TGFPSCYPT---PSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPR 511
C C GF P P P S + VLPA + CD P
Sbjct: 371 CQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCD--------------PS 416
Query: 512 VGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGVADDRCDPDTGQC 560
G C CKP G C+ C G++G GC+PC C+ CDP TG C
Sbjct: 417 NGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAG------SCDPITGDC 462
Score = 90.5 bits (223), Expect = 3e-17
Identities = 75/275 (27%), Positives = 107/275 (38%), Gaps = 44/275 (16%)
Query: 1864 CQCHGHSDRCLPGSGV---------------CVDCQHNTEGAHCERC-----QAGFVSSR 1903
C C+GH+D+C+P G C+ C+HNT G+HC+ C + ++
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 1904 DDPSAP--CVSCPCPLSVPSNNFA----EGCVLRGGRTQCLCKPGYAGASCERCAPGFFG 1957
AP C +C C + +F E R G C+ G C+RC PGF+
Sbjct: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
Query: 1958 N---PLVLGSSCQPCDCSGNGD---PNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
+ P +C+PC C G P + CDP G C C G RC+ C G++
Sbjct: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYW 439
Query: 2012 GNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCA 2071
G C CDC +CDP +G C+ + D E P
Sbjct: 440 GFG--DYGCRPCDC----AGSCDPITGDCIS----SHTDIDWYHEVPDFRPVHNKSEPAW 489
Query: 2072 CGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGY 2106
A+G SG+C C+ T+G C Y
Sbjct: 490 EWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKY 524
Score = 86.3 bits (212), Expect = 5e-16
Identities = 68/238 (28%), Positives = 94/238 (39%), Gaps = 60/238 (25%)
Query: 513 GRCLCKPNFQGTHCELCAPGFY------------GPG-CQPCQCSSPGVADDRCDPDT-- 557
G+C+CK N G+HC+ CAP + P C+ C+C+ D C D
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHA---DTCHFDVNV 347
Query: 558 ---------GQCR-CRVGFEGATCDRCAPGYFHF--------PLCQLCGCSPAGT--LPE 597
G C C+ EG C RC PG++ C+ C C P G+ LP
Sbjct: 348 WEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPA 407
Query: 598 G----CDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRC 652
CD + G C C+P AG CDRC GY GF + CD G+ D + G C
Sbjct: 408 NSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITG-----DC 462
Query: 653 RPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLH------AACDPRSGQCSCRPRVTG 704
+T +H P P H +E + + SG+C C+ + G
Sbjct: 463 ISSHTDI------DWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLG 514
Score = 83.2 bits (204), Expect = 4e-15
Identities = 67/215 (31%), Positives = 81/215 (37%), Gaps = 59/215 (27%)
Query: 1428 SLFYNNGARPC----GCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGY----W--- 1476
S F N A C G V A G T G+C C + G C CA Y W
Sbjct: 261 SCFCNGHADQCIPVHGFRPVKAPG-TFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAA 319
Query: 1477 ----GFPN-CRPCDCGAR--------------------LCDELTGQCICPPRTIPPDCLL 1511
G PN CR C C +CD+ C T C
Sbjct: 320 DGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQR 373
Query: 1512 CQPQTFGC--HPLVG---CEECNCSGPGIQELTDPT---CDTDSGQCKCRPNVTGRRCDT 1563
C+P + P C+ C+C G L + CD +G C C+P V GRRCD
Sbjct: 374 CKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDR 433
Query: 1564 CSPGFHGYP--RCRPCDCHEAGTAPGVCDPLTGQC 1596
C G+ G+ CRPCDC G CDP+TG C
Sbjct: 434 CMVGYWGFGDYGCRPCDC------AGSCDPITGDC 462
Score = 81.6 bits (200), Expect = 1e-14
Identities = 53/165 (32%), Positives = 69/165 (41%), Gaps = 27/165 (16%)
Query: 1433 NGARPCGCHEVGA------TGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN--CRPC 1484
+ +PC CH VG+ + C+P G CPC V GR C RC GYWGF + CRPC
Sbjct: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
Query: 1485 DCGARLCDELTGQCICPPRTIP-----PDCLLCQPQTFGCHPLVGCEECNCSGPGIQELT 1539
DC A CD +TG CI I PD +P P E+ G L
Sbjct: 450 DC-AGSCDPITGDCISSHTDIDWYHEVPD---FRPVHNKSEPAWEWEDAQ----GFSAL- 500
Query: 1540 DPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGT 1584
SG+C+C+ G C + + + H+ GT
Sbjct: 501 -----LHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGT 540
Score = 65.1 bits (157), Expect = 1e-09
Identities = 45/147 (30%), Positives = 55/147 (37%), Gaps = 42/147 (28%)
Query: 2038 GHCLCKAGVTGRRCDRCQ--------EGHFGFDGCGG-CRPCACGPAAEGSECH------ 2082
G C+CK G C C E G G CR C C A+ CH
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHAD--TCHFDVNVW 348
Query: 2083 -----PQSGQCH-CRPGTMGPQCRECAPGYW-------GLPEQGCRRCQC-PGGR----- 2123
G C C+ T G C+ C PG++ P+ C+ C C P G
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPD-ACKPCSCHPVGSAVLPA 407
Query: 2124 -----CDPHTGRCNCPPGLSGERCDTC 2145
CDP G C C PG++G RCD C
Sbjct: 408 NSVTFCDPSNGDCPCKPGVAGRRCDRC 434
Score = 50.8 bits (120), Expect = 2e-05
Identities = 51/199 (25%), Positives = 67/199 (33%), Gaps = 51/199 (25%)
Query: 674 CVPCH----CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAG 729
C+P H A G+ H G+C C+ G C C P YN EA
Sbjct: 271 CIPVHGFRPVKAPGTFHMV----HGKCMCKHNTAGSHCQHCAP-LYNDRPWEA------- 318
Query: 730 LAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAE 789
A P C C H + D W S + G CD +
Sbjct: 319 -ADGKTGAPNECRTCKCNGHADTCHFD---VNVWEASGNRSGGV----CD---------D 361
Query: 790 CQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFG---CRSCRCD-IGGALGQS----- 840
CQ T GQ C CK GF+ + + C+ C C +G A+ +
Sbjct: 362 CQHNTE---------GQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 841 CEPRTGVCRCRPNTQGPTC 859
C+P G C C+P G C
Sbjct: 413 CDPSNGDCPCKPGVAGRRC 431
Score = 37.7 bits (86), Expect = 0.21
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 22/97 (22%)
Query: 1548 GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
G C C + D C P HG+ RP APG + G+C CK N G C
Sbjct: 260 GSCFCNGHA-----DQCIP-VHGF---RPVK------APGTFHMVHGKCMCKHNTAGSHC 304
Query: 1608 DQCS--LGTFSLDAAN-----PKGCTRCFCFGATERC 1637
C+ +AA+ P C C C G + C
Sbjct: 305 QHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTC 341
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 223 bits (568), Expect = 3e-57
Identities = 198/638 (31%), Positives = 243/638 (38%), Gaps = 132/638 (20%)
Query: 296 IGGRCVCHG--HADACDAKDPTDPFRLQCTCQHN-TCGGTCDRC-----CPGFNQQP--- 344
+ G C C C+ P F L C N T G CD CP + P
Sbjct: 928 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 987
Query: 345 -WKPATANSANECQSCNCYGHAT------DCYYDPEVDRRRASQSLD-GTY--------- 387
PA N Q+C C+ A+ C+ P Q+ G Y
Sbjct: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
Query: 388 -QGGGVC------IDCQHHTTGVNCER-CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT 439
Q GG C C G+ CE+ CLP R+ CR G
Sbjct: 1048 CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAG---------CRHSG--GCLNGGL 1096
Query: 440 CEDLTGRCYCRPNFSGERCDV-CAEGFTGFP-----SCYP-------------TPSSSND 480
C+ TGRC C ++G++C C G+ G SC P P +
Sbjct: 1097 CDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGS 1156
Query: 481 TREQVLPAGQIVN-----CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFY 534
EQ P G C C + AC P G C C + G C+ C PG Y
Sbjct: 1157 GCEQACPPGSFGEDCAQMCQCPG---ENPACH--PATGTCSCAAGYHGPSCQQRCPPGRY 1211
Query: 535 GPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD-RCAPGYFHFPLCQLCGCSPA 592
GPGC Q C C + G CD TG CRC GF G C+ C G F +CGC
Sbjct: 1212 GPGCEQLCGCLNGG----SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG 1267
Query: 593 GTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNCQ-ACTCDPRGALDQLCGAG-GL 649
CD G CLC P AG C+R P C+ C+C G LC A G
Sbjct: 1268 AA----CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG----LCHASNGS 1319
Query: 650 CRCRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCD 708
C C G+TG C+ C PG +G CH ++ C+P +G C C P G C+
Sbjct: 1320 CSCGLGWTGRHCELACPPGRYG----AACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Query: 709 TCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSP 767
P ++ C+ G C AP DP C+C A G C+R C+PG +G
Sbjct: 1376 HPCPPGFHGAGCQ-GLCWCQHGAPCDPISGR----CLCPAGFHGHFCERGCEPGSFG--- 1427
Query: 768 SNPEGC-TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFG 825
EGC RC CD G A C P TG C C P G C C+ G FG
Sbjct: 1428 ---EGCHQRCDCD------GGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG-------- 1470
Query: 826 CRSC--RCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
SC CD GG G C+P +G C C GPTC E
Sbjct: 1471 -PSCTLHCDCGG--GADCDPVSGQCHCVDGYMGPTCRE 1505
Score = 202 bits (513), Expect = 7e-51
Identities = 183/615 (29%), Positives = 224/615 (36%), Gaps = 121/615 (19%)
Query: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCP-GFNQQPWKPATANSANECQ 357
RC C H ACD CTC G C+ CP GF +C+
Sbjct: 916 RCQCQ-HGAACDHVSGA------CTCPAGWRGTFCEHACPAGF-----------FGLDCR 957
Query: 358 S-CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSP 416
S CNC A D S +G C HT G NC +
Sbjct: 958 SACNCTAGAA-------CDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQA-------- 1002
Query: 417 NHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFP---SCY 472
C C F +C+ + G+C+C P + G C C G G SC
Sbjct: 1003 ------------CAC---FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
Query: 473 PTPSSSNDT----------------REQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCL 516
+ D ++ LP C S G C DP GRCL
Sbjct: 1048 CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLC--DPHTGRCL 1105
Query: 517 CKPNFQGTHCEL-CAPGFYGPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR- 573
C + G C+ C G++G C Q C C PG A C TG CRC GF G+ C++
Sbjct: 1106 CPAGWTGDKCQSPCLRGWFGEACAQRCSCP-PGAA---CHHVTGACRCPPGFTGSGCEQA 1161
Query: 574 CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCD-RCRPGYHGFPNC-QA 631
C PG F Q+C C G P G C C + GP C RC PG +G P C Q
Sbjct: 1162 CPPGSFGEDCAQMCQCP--GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG-PGCEQL 1218
Query: 632 CTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDP 691
C C G+ D GA CRC G+ GT C P P+C +G AACDP
Sbjct: 1219 CGCLNGGSCDAATGA---CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQG---AACDP 1272
Query: 692 RSGQCSCRPRVTGLRCDTCVPGAYNFPYCE-AGSCHPAGLAPVDPALPEAQVPCMCRAHV 750
+G C C P G+RC+ P CE SC GL C C
Sbjct: 1273 VTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG------SCSCGLGW 1326
Query: 751 EGPSCD-RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA 809
G C+ C PG +G + CSC T C+P TG C C P GQAC
Sbjct: 1327 TGRHCELACPPGRYGAACH-----LECSCHNNST------CEPATGTCRCGPGFYGQACE 1375
Query: 810 S-CKDGFFGLDQADYFGCRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
C GF G GC+ C C G C+P +G C C G C
Sbjct: 1376 HPCPPGFHGA------GCQGLCWCQHGAP----CDPISGRCLCPAGFHGHFCERGCEPGS 1425
Query: 868 LPDLHHLRLELEEAA 882
+ H R + + A
Sbjct: 1426 FGEGCHQRCDCDGGA 1440
Score = 200 bits (508), Expect = 2e-50
Identities = 183/649 (28%), Positives = 232/649 (35%), Gaps = 141/649 (21%)
Query: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC 361
C AC DP C C G C CP P + AN+
Sbjct: 782 CQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPA 841
Query: 362 YGHAT--------DC-------YYDPEVDRRRASQSLDGTYQG-GGVCIDCQHHTTGVNC 405
GH + C ++ P+ + G+ G+C+ C+ G C
Sbjct: 842 TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL-CEAGYVGPRC 900
Query: 406 E-RCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAE 463
E +C G + P +RC C+ C+ ++G C C + G C+ C
Sbjct: 901 EQQCPQGHF--------GPGCEQRCQCQH---GAACDHVSGACTCPAGWRGTFCEHACPA 949
Query: 464 GFTGF---PSCYPTPSSSND--TREQVLPAGQ------------IVNCDCSAAGTQGNAC 506
GF G +C T ++ D + PAG+ +CS A N
Sbjct: 950 GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGA 1009
Query: 507 RKDPRVGRCLCKPNFQGTHC-ELCAPGFYGPGCQ-PCQCSSPGVADDRCDPDTGQCRCRV 564
DP G+C C P + G C + C G YG C+ C C + G CDP +G C C
Sbjct: 1010 SCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGT----CDPVSGHCACPE 1065
Query: 565 GFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEG--CD-EAGRCLCQPEFAGPHCDR-C 619
G+ G C++ C P GC +G G CD GRCLC + G C C
Sbjct: 1066 GWAGLACEKECLPRDVR------AGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPC 1119
Query: 620 RPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTAC-QECSPGFHGFPSCVPCH 678
G+ G Q C+C P A + GA CRC PG+TG+ C Q C PG G C
Sbjct: 1120 LRGWFGEACAQRCSCPPGAACHHVTGA---CRCPPGFTGSGCEQACPPGSFGEDCAQMCQ 1176
Query: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRC-DTCVPGAYNFPYCE-------AGSCHPAGL 730
C E + AC P +G CSC G C C PG Y P CE GSC A
Sbjct: 1177 CPGE---NPACHPATGTCSCAAGYHGPSCQQRCPPGRYG-PGCEQLCGCLNGGSCDAATG 1232
Query: 731 APVDPALPEAQVPCMCRAHVEGPSCD-RCKPGFWGLSPSNPEGCTR-CSCDLRGTLGGVA 788
A C C G C+ C G +G CT C C G A
Sbjct: 1233 A------------CRCPTGFLGTDCNLTCPQGRFG------PNCTHVCGC------GQGA 1268
Query: 789 ECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFGCR----------SCRCDIG--- 834
C P TG C C P G C C FG+ CR SC C +G
Sbjct: 1269 ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTG 1328
Query: 835 ---------GALG------------QSCEPRTGVCRCRPNTQGPTCSEP 862
G G +CEP TG CRC P G C P
Sbjct: 1329 RHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHP 1377
Score = 198 bits (503), Expect = 9e-50
Identities = 176/578 (30%), Positives = 221/578 (38%), Gaps = 125/578 (21%)
Query: 316 DPFRLQC--TCQHNTCGGTC----DRC-CPGFNQQPWKPATANSANECQSCNCYGHATDC 368
D F C TC GGTC D C CP + W N ++C +C
Sbjct: 514 DSFGHDCSLTCDDCRNGGTCLLGLDGCDCP----EGWTGLICN-----ETCPPDTFGKNC 564
Query: 369 YYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCER-CLPGFYRSPNHPLDSPHVCR 427
+ S+ G + C +G NCE C G+Y H +
Sbjct: 565 SFSCSCQNGGTCDSVTGACR-------CPPGVSGTNCEDGCPKGYY--------GKHCRK 609
Query: 428 RCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP 487
+CNC + G C L G C C P G C + + P C
Sbjct: 610 KCNCANR---GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSE-------------- 652
Query: 488 AGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGC-QPCQCSS 545
C C TQ +C D R G C CK F+G C+ C G++GPGC Q C C
Sbjct: 653 -----ECQCVQPHTQ--SC--DKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703
Query: 546 PGVADDRCDPDTGQC--RCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEA 602
GVA CD +G+C RC GF+G C + C G F C C G G
Sbjct: 704 -GVA---CDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG--GAPCHGV--T 755
Query: 603 GRCLCQPEFAGPHCDR-CRPGYHGF------PNCQ-ACTCDPRGALDQLCGAGGLCRCRP 654
G+C C P G C+ C G G P CQ A CDP G C C P
Sbjct: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPET---------GACLCLP 806
Query: 655 GYTGTACQE-CSPGFHGFPSC-VPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVP 712
G+ G+ CQ+ C G++G PSC C C+ +G C P +G CSC P TG C
Sbjct: 807 GFVGSRCQDVCPAGWYG-PSCQTRCSCANDGH----CHPATGHCSCAPGWTGFSCQRACD 861
Query: 713 GAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNPE 771
+ P C HP + + C+C A GP C++ C G +G
Sbjct: 862 TGHWGPDCS----HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG------P 911
Query: 772 GCT-RCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQADYFGCRS- 828
GC RC C A C +G C C G C +C GFFGLD CRS
Sbjct: 912 GCEQRCQCQHG------AACDHVSGACTCPAGWRGTFCEHACPAGFFGLD------CRSA 959
Query: 829 CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
C C G A C+ G C C +GP C+E H
Sbjct: 960 CNCTAGAA----CDAVNGSCLCPAGRRGPRCAETCPAH 993
Score = 185 bits (470), Expect = 6e-46
Identities = 169/598 (28%), Positives = 218/598 (36%), Gaps = 119/598 (19%)
Query: 309 CDAKDPTDPF----RLQCTCQHNTCGGTCD------RCCPGFNQQPWKPATANSANECQS 358
C+ P D F C+CQ+ GGTCD RC PG +
Sbjct: 551 CNETCPPDTFGKNCSFSCSCQN---GGTCDSVTGACRCPPGVS----------------G 591
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
NC YY ++ + ++ G C+ C G C P + P
Sbjct: 592 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL-CDPGLYGRFCHLTCPPWAFGPG- 649
Query: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGFTGFPSCY----- 472
C C T +C+ G C C+ F GERC C G+ G P C+
Sbjct: 650 ------CSEECQCVQPHTQ-SCDKRDGSCSCKAGFRGERCQAECELGYFG-PGCWQACTC 701
Query: 473 -----------------PTPSSSNDTREQVLPAGQI-VNCD--CSAAGTQGNACRKDPRV 512
P D ++ P G VNC CS G +
Sbjct: 702 PVGVACDSVSGECGKRCPAGFQGEDCGQEC-PVGTFGVNCSSSCSCGGAPCHGV-----T 755
Query: 513 GRCLCKPNFQGTHCEL-CAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATC 571
G+C C P G CE C G +G GCQ + A RCDP+TG C C GF G+ C
Sbjct: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA--RCDPETGACLCLPGFVGSRC 813
Query: 572 DRCAPGYFHFPLCQL-CGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGYHGFPNC 629
P ++ P CQ C C+ G C A G C C P + G C R H P+C
Sbjct: 814 QDVCPAGWYGPSCQTRCSCANDG----HCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC 869
Query: 630 -QACTCDP-RGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVP-CHCSAEGSLH 686
C C G+ D + GLC C GY G C++ P H P C C C
Sbjct: 870 SHPCNCSAGHGSCDAI---SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQH----G 922
Query: 687 AACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMC 746
AACD SG C+C G C+ P + C + AG A C+C
Sbjct: 923 AACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAG-----AACDAVNGSCLC 977
Query: 747 RAHVEGPSC-DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCG 805
A GP C + C +G C++ G A C P GQC C P G
Sbjct: 978 PAGRRGPRCAETCPAHTYG------HNCSQACACFNG-----ASCDPVHGQCHCAPGWMG 1026
Query: 806 QAC-ASCKDGFFGLDQADYFGCR-SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
+C +C G +G CR SC C GG +C+P +G C C G C +
Sbjct: 1027 PSCLQACPAGLYG------DNCRHSCLCQNGG----TCDPVSGHCACPEGWAGLACEK 1074
Score = 162 bits (411), Expect = 4e-39
Identities = 144/458 (31%), Positives = 175/458 (38%), Gaps = 95/458 (20%)
Query: 298 GRCVCHGH--ADACDAKDPTDPFRLQCT----------CQHNTCGGTCDRCCPGFNQQPW 345
GRC+C D C + F C C H T G C RC PGF
Sbjct: 1102 GRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVT--GAC-RCPPGFTGSGC 1158
Query: 346 KPAT--ANSANEC-QSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTG 402
+ A + +C Q C C G C+ G C C G
Sbjct: 1159 EQACPPGSFGEDCAQMCQCPGENPACH------------------PATGTC-SCAAGYHG 1199
Query: 403 VNCE-RCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV- 460
+C+ RC PG Y P + C C G+C+ TG C C F G C++
Sbjct: 1200 PSCQQRCPPGRY--------GPGCEQLCGC---LNGGSCDAATGACRCPTGFLGTDCNLT 1248
Query: 461 ---------------CAEGFTGFP---SCYPTPSSSNDTREQVLPAGQI-VNCDCSAAGT 501
C +G P +C P + E+ P + V C+ + +
Sbjct: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
Query: 502 QGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGCQ-PCQCSSPGVADDRCDPDTGQ 559
G C G C C + G HCEL C PG YG C C C + + C+P TG
Sbjct: 1309 NGGLCHASN--GSCSCGLGWTGRHCELACPPGRYGAACHLECSCHN----NSTCEPATGT 1362
Query: 560 CRCRVGFEGATCDRCAPGYFHFPLCQ-LCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCD 617
CRC GF G C+ P FH CQ LC C CD +GRCLC F G C+
Sbjct: 1363 CRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAP----CDPISGRCLCPAGFHGHFCE 1418
Query: 618 R-CRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCV 675
R C PG G Q C CD D + GLC C PG +G C +C G G PSC
Sbjct: 1419 RGCEPGSFGEGCHQRCDCDGGAPCDPVT---GLCLCPPGRSGATCNLDCRRGQFG-PSCT 1474
Query: 676 PCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPG 713
HC G A CDP SGQC C V G TC G
Sbjct: 1475 -LHCDCGGG--ADCDPVSGQCHC---VDGYMGPTCREG 1506
Score = 151 bits (382), Expect = 1e-35
Identities = 125/389 (32%), Positives = 155/389 (39%), Gaps = 88/389 (22%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C CP + G C++ P G F C CQC G + C P +G C C G
Sbjct: 1147 CRCPPGFTGSGCEQACP------PGSFGEDCAQMCQCPGENPACHPATGTC-SCAAGYHG 1199
Query: 1890 AHCE-RCQAGFVSSRDDPSAPCVS------------CP-------CPLSVPSNNFAEGCV 1929
C+ RC G + C++ CP C L+ P F C
Sbjct: 1200 PSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCT 1259
Query: 1930 LRGGRTQ----------CLCKPGYAGASCERCAPGFFGNPLVLGSSCQ-PCDCSGNGDPN 1978
G Q CLC PG AG CER P G C+ C C G
Sbjct: 1260 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP-----QNRFGVGCEHTCSCRNGGL-- 1312
Query: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHS 2037
C G+C C TG CE+ C PG YG A +C+ C+P +
Sbjct: 1313 -----CHASNGSC-SCGLGWTGRHCELACPPGRYGAAC------HLECSCHNNSTCEPAT 1360
Query: 2038 GHCLCKAGVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMG 2096
G C C G G+ C+ C G G GC G C C G+ C P SG+C C G G
Sbjct: 1361 GTCRCGPGFYGQACEHPCPPGFHGA-GCQGL--CWC---QHGAPCDPISGRCLCPAGFHG 1414
Query: 2097 PQC-RECAPGYWGLPEQGC-RRCQCPGGR-CDPHTGRCNCPPGLSGERCDTCSQQHQVPV 2153
C R C PG +G +GC +RC C GG CDP TG C CPPG SG C+ ++ Q
Sbjct: 1415 HFCERGCEPGSFG---EGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQF-- 1469
Query: 2154 PGGPVGHSIHCEV-----CD------HCV 2171
GP ++HC+ CD HCV
Sbjct: 1470 --GP-SCTLHCDCGGGADCDPVSGQCHCV 1495
Score = 144 bits (363), Expect = 2e-33
Identities = 129/449 (28%), Positives = 160/449 (35%), Gaps = 145/449 (32%)
Query: 1833 CPASYRGDSC-QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCL-----PGSGVCVDCQHN 1886
CPA ++G+ C QEC G + V C CHG + +C G DC
Sbjct: 718 CPAGFQGEDCGQECPVGTF-GVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEG 776
Query: 1887 TEGAHCER-CQAGFVSSRDDP-SAPCVSCP------CPLSVPSNNFAEGCVLR------- 1931
G C+ C A ++R DP + C+ P C P+ + C R
Sbjct: 777 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG 836
Query: 1932 ---GGRTQCLCKPGYAGASCER-CAPGFFGNPLVLGSSCQPCDCS-GNGDPNLLFSDCDP 1986
C C PG+ G SC+R C G +G PC+CS G+G CD
Sbjct: 837 HCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCSHPCNCSAGHGS-------CDA 884
Query: 1987 LTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAG 2045
++G C C GPRCE C G +G PG RC C ACD SG C C AG
Sbjct: 885 ISGLCL-CEAGYVGPRCEQQCPQGHFG----PGCEQRCQCQHGA--ACDHVSGACTCPAG 937
Query: 2046 VTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAE--------------------------- 2077
G C+ C G FG D C C G A +
Sbjct: 938 WRGTFCEHACPAGFFGLDCRSACN-CTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
Query: 2078 -----------GSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRR---------- 2116
G+ C P GQCHC PG MGP C + P GL CR
Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPA--GLYGDNCRHSCLCQNGGTC 1054
Query: 2117 ------CQCP-----------------------------GGRCDPHTGRCNCPPGLSGER 2141
C CP GG CDPHTGRC CP G +G++
Sbjct: 1055 DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDK 1114
Query: 2142 C----------DTCSQQHQVPVPGGPVGH 2160
C + C+Q+ P PG H
Sbjct: 1115 CQSPCLRGWFGEACAQRCSCP-PGAACHH 1142
Score = 138 bits (347), Expect = 1e-31
Identities = 128/446 (28%), Positives = 163/446 (36%), Gaps = 134/446 (30%)
Query: 1819 AGQGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGS 1877
AG G+ + LCLC A Y G C++ P +G F C CQC H C S
Sbjct: 877 AGHGSCDAISGLCLCEAGYVGPRCEQQCP------QGHFGPGCEQRCQCQ-HGAACDHVS 929
Query: 1878 GVCVDCQHNTEGAHCER-CQAGFVSSRDDPSAPCVS------------CP---------- 1914
G C C G CE C AGF + C + CP
Sbjct: 930 GACT-CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE 988
Query: 1915 -CPLSVPSNNFAEGCVLRGGRT------QCLCKPGYAGASC-ERCAPGFFGNPL------ 1960
CP +N ++ C G + QC C PG+ G SC + C G +G+
Sbjct: 989 TCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLC 1048
Query: 1961 VLGSSCQP----CDCSGNG-----DPNLLFSD----------------CDPLTGACRGCL 1995
G +C P C C + L D CDP TG C C
Sbjct: 1049 QNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCL-CP 1107
Query: 1996 RHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDR- 2053
TG +C+ C G++G A RC C P AC +G C C G TG C++
Sbjct: 1108 AGWTGDKCQSPCLRGWFGEAC----AQRCSCPPGA--ACHHVTGACRCPPGFTGSGCEQA 1161
Query: 2054 CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQ 2112
C G FG D C + C C E CHP +G C C G GP C++ C PG +G
Sbjct: 1162 CPPGSFGED-CA--QMCQC--PGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG---P 1213
Query: 2113 GCRR----------------CQCP-----------------------------GGRCDPH 2127
GC + C+CP G CDP
Sbjct: 1214 GCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPV 1273
Query: 2128 TGRCNCPPGLSGERCDTCSQQHQVPV 2153
TG C CPPG +G RC+ Q++ V
Sbjct: 1274 TGTCLCPPGRAGVRCERGCPQNRFGV 1299
Score = 125 bits (315), Expect = 6e-28
Identities = 100/308 (32%), Positives = 122/308 (39%), Gaps = 67/308 (21%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C CP + G C P +G F C C C G C P +G C+ C G
Sbjct: 1234 CRCPTGFLGTDCNLTCP------QGRFGPNCTHVCGC-GQGAACDPVTGTCL-CPPGRAG 1285
Query: 1890 AHCER----------------CQAGFVSSRDDPSAPC----VSCPCPLSVPSNNFAEGCV 1929
CER C+ G + + S C C L+ P + C
Sbjct: 1286 VRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACH 1345
Query: 1930 LR----------GGRTQCLCKPGYAGASCER-CAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
L C C PG+ G +CE C PGF G + CQ +G P
Sbjct: 1346 LECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHG------AGCQGLCWCQHGAP- 1398
Query: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHS 2037
CDP++G C C G CE C PG +G G RCDC G CDP +
Sbjct: 1399 -----CDPISGRCL-CPAGFHGHFCERGCEPGSFGE----GCHQRCDCD--GGAPCDPVT 1446
Query: 2038 GHCLCKAGVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMG 2096
G CLC G +G C+ C+ G FG C C CG G++C P SGQCHC G MG
Sbjct: 1447 GLCLCPPGRSGATCNLDCRRGQFG-PSC--TLHCDCGG---GADCDPVSGQCHCVDGYMG 1500
Query: 2097 PQCRECAP 2104
P CRE P
Sbjct: 1501 PTCREGGP 1508
Score = 122 bits (306), Expect = 7e-27
Identities = 119/405 (29%), Positives = 154/405 (38%), Gaps = 67/405 (16%)
Query: 1822 GALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD------RCLP 1875
G ++ C CP + G C E P D G CQ G D RC P
Sbjct: 531 GTCLLGLDGCDCPEGWTGLICNETCPP---DTFGKNCSFSCSCQNGGTCDSVTGACRCPP 587
Query: 1876 G-SGV-CVD-CQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSCP------CPLSVPSNNFA 1925
G SG C D C G HC ++C C+ P C L+ P F
Sbjct: 588 GVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFG 647
Query: 1926 EGCVLRGGRTQ------------CLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQPCDCS 1972
GC Q C CK G+ G C+ C G+FG Q C C
Sbjct: 648 PGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGP-----GCWQACTCP 702
Query: 1973 GNGDPNLLFSDCDPLTGAC-RGCLRHTTGPRC-EICAPGFYGNALLPGNCTRCDCTPCGT 2030
+ CD ++G C + C G C + C G +G NC+ C+ CG
Sbjct: 703 -------VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGV-----NCSS-SCS-CGG 748
Query: 2031 EACDPHSGHCLCKAGVTGRRCDR-CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCH 2089
C +G C C G TG C+ C EG +G GC+ C + C P++G C
Sbjct: 749 APCHGVTGQCRCPPGRTGEDCEADCPEGRWGL----GCQEI-CPACQHAARCDPETGACL 803
Query: 2090 CRPGTMGPQCRECAPGYWGLPEQGCR-RCQCPG-GRCDPHTGRCNCPPGLSGERCD-TCS 2146
C PG +G +C++ P W P C+ RC C G C P TG C+C PG +G C C
Sbjct: 804 CLPGFVGSRCQDVCPAGWYGPS--CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACD 861
Query: 2147 QQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQ 2191
H P P S CD L L + AG + P +Q
Sbjct: 862 TGHWGPDCSHPCNCSAGHGSCDAISGLCLCE---AGYVGPRCEQQ 903
Score = 110 bits (274), Expect = 3e-23
Identities = 77/231 (33%), Positives = 98/231 (42%), Gaps = 26/231 (11%)
Query: 1416 SSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATG 1474
+ L C N F N + C C G TC+ G C C V G +C C G
Sbjct: 547 TGLIC-NETCPPDTFGKNCSFSCSCQN----GGTCDSVTGACRCPPGVSGTNCEDGCPKG 601
Query: 1475 YWGFPNCRPCDCGAR-LCDELTGQCICPPRTIPPDC-LLCQPQTFGCHPLVGC-EECNCS 1531
Y+G + C+C R C L G C+C P C L C P FG GC EEC C
Sbjct: 602 YYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFG----PGCSEECQCV 657
Query: 1532 GPGIQELTDPTCDTDSGQCKCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCD 1590
P Q +CD G C C+ G RC C G+ G + C C G A CD
Sbjct: 658 QPHTQ-----SCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTC-PVGVA---CD 708
Query: 1591 PLTGQC--YCKENVQGPKCDQ-CSLGTFSLDAANPKGCTRCFCFGATERCR 1638
++G+C C QG C Q C +GTF ++ ++ C C G T +CR
Sbjct: 709 SVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCR 759
Score = 99.0 bits (245), Expect = 8e-20
Identities = 78/239 (32%), Positives = 99/239 (41%), Gaps = 63/239 (26%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNC-RPCDCG-ARLCDEL 1494
CGC G +C+ G C C +G DC+ C G +G PNC C CG CD +
Sbjct: 1219 CGC----LNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFG-PNCTHVCGCGQGAACDPV 1273
Query: 1495 TGQCICPPRTIPPDCLLCQPQT-FGCHPLVGCEE-CNCSGPGIQ---------------- 1536
TG C+CPP C PQ FG VGCE C+C G+
Sbjct: 1274 TGTCLCPPGRAGVRCERGCPQNRFG----VGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1329
Query: 1537 --ELTDP------------------TCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPRCR 1575
EL P TC+ +G C+C P G+ C+ C PGFHG
Sbjct: 1330 HCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQG 1389
Query: 1576 PCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGC-TRCFCFG 1632
C C AP CDP++G+C C G C++ C G+F +GC RC C G
Sbjct: 1390 LCWCQHG--AP--CDPISGRCLCPAGFHGHFCERGCEPGSFG------EGCHQRCDCDG 1438
Score = 97.8 bits (242), Expect = 2e-19
Identities = 73/242 (30%), Positives = 99/242 (40%), Gaps = 34/242 (14%)
Query: 1404 CAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGP------------TCE 1451
C+ + + P + S R+ + S + C E+G GP C+
Sbjct: 650 CSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAEC-ELGYFGPGCWQACTCPVGVACD 708
Query: 1452 PFGGQCP--CHAHVIGRDCSR-CATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPD 1508
G+C C A G DC + C G +G C CG C +TGQC CPP D
Sbjct: 709 SVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGED 768
Query: 1509 CLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSP 1566
C C +G +GC+E C P Q CD ++G C C P G RC D C
Sbjct: 769 CEADCPEGRWG----LGCQEI-C--PACQHAA--RCDPETGACLCLPGFVGSRCQDVCPA 819
Query: 1567 GFHGYPRCRP-CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKG 1624
G++G P C+ C C G C P TG C C G C + C G + D ++P
Sbjct: 820 GWYG-PSCQTRCSC----ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 874
Query: 1625 CT 1626
C+
Sbjct: 875 CS 876
Score = 91.3 bits (225), Expect = 2e-17
Identities = 73/247 (29%), Positives = 91/247 (36%), Gaps = 48/247 (19%)
Query: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCR-PCDC-GA 1488
+N ++ C C G +C+P GQC C +G C + C G +G NCR C C
Sbjct: 997 HNCSQACACFN----GASCDPVHGQCHCAPGWMGPSCLQACPAGLYG-DNCRHSCLCQNG 1051
Query: 1489 RLCDELTGQCICP-------------PRTIPPDCL---------LCQPQTFGCHPLVGCE 1526
CD ++G C CP PR + C LC P T C G
Sbjct: 1052 GTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWT 1111
Query: 1527 ECNCSGPGI---------QELTDP---TCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPR 1573
C P + Q + P C +G C+C P TG C+ C PG G
Sbjct: 1112 GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDC 1171
Query: 1574 CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCTR-CFCF 1631
+ C C A C P TG C C GP C Q C G + GC C
Sbjct: 1172 AQMCQCPGENPA---CHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1228
Query: 1632 GATERCR 1638
AT CR
Sbjct: 1229 AATGACR 1235
Score = 91.3 bits (225), Expect = 2e-17
Identities = 90/320 (28%), Positives = 112/320 (35%), Gaps = 81/320 (25%)
Query: 305 HADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ-SCNCYG 363
H C DP C C G C+R CP C+ +C+C
Sbjct: 1260 HVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP----------QNRFGVGCEHTCSC-- 1307
Query: 364 HATDCYYDPEVDRRRASQSLDGTYQGGGVC------IDCQHHTTGVNCE-RCLPGFYRSP 416
+ GG+C C TG +CE C PG Y +
Sbjct: 1308 ------------------------RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAA 1343
Query: 417 NHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAEGFTGFPS---CY 472
H C+C ++ TCE TG C C P F G+ C+ C GF G C+
Sbjct: 1344 CH--------LECSCHNN---STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCW 1392
Query: 473 PTPSSSND--TREQVLPAG---QIVNCDCSAAGTQGNACRK----------DPRVGRCLC 517
+ D + + PAG C G+ G C + DP G CLC
Sbjct: 1393 CQHGAPCDPISGRCLCPAGFHGHFCERGCEP-GSFGEGCHQRCDCDGGAPCDPVTGLCLC 1451
Query: 518 KPNFQGTHCEL-CAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAP 576
P G C L C G +GP C C G AD CDP +GQC C G+ G TC P
Sbjct: 1452 PPGRSGATCNLDCRRGQFGPSCT-LHCDCGGGAD--CDPVSGQCHCVDGYMGPTCREGGP 1508
Query: 577 GYFHFPLCQLCGCSPAGTLP 596
P AGTLP
Sbjct: 1509 --LRLPENPSLAQGSAGTLP 1526
Score = 89.4 bits (220), Expect = 6e-17
Identities = 61/178 (34%), Positives = 79/178 (44%), Gaps = 30/178 (16%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRP---CDCGARLCDE 1493
C CH TCEP G C C G+ C C G+ G C+ C GA CD
Sbjct: 1348 CSCHN----NSTCEPATGTCRCGPGFYGQACEHPCPPGFHG-AGCQGLCWCQHGAP-CDP 1401
Query: 1494 LTGQCICPPRTIPPDCLL-CQPQTFG--CHPLVGCEECNCSGPGIQELTDPTCDTDSGQC 1550
++G+C+CP C C+P +FG CH + C+C G CD +G C
Sbjct: 1402 ISGRCLCPAGFHGHFCERGCEPGSFGEGCH-----QRCDCDGGA-------PCDPVTGLC 1449
Query: 1551 KCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
C P +G C+ C G G CDC G A CDP++GQC+C + GP C
Sbjct: 1450 LCPPGRSGATCNLDCRRGQFGPSCTLHCDC--GGGAD--CDPVSGQCHCVDGYMGPTC 1503
Score = 88.2 bits (217), Expect = 1e-16
Identities = 74/278 (26%), Positives = 109/278 (39%), Gaps = 40/278 (14%)
Query: 1403 HCAAQGYHIS--PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCH 1460
HC H S P + C+ A + + + + PC C A +C+ G C C
Sbjct: 837 HCHPATGHCSCAPGWTGFSCQRACDT-GHWGPDCSHPCNC---SAGHGSCDAISGLCLCE 892
Query: 1461 AHVIGRDCSR-CATGYWGFPNCRP-CDCG-ARLCDELTGQCICPPRTIPPDCL-LCQPQT 1516
A +G C + C G++G P C C C CD ++G C CP C C
Sbjct: 893 AGYVGPRCEQQCPQGHFG-PGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF 951
Query: 1517 FGCHPLVGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFHGYPRC 1574
FG + C CNC+ CD +G C C G RC +TC +G+
Sbjct: 952 FG----LDCRSACNCTAGA-------ACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCS 1000
Query: 1575 RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCTR-CFCFG 1632
+ C C + CDP+ GQC+C GP C Q C G + + + C C
Sbjct: 1001 QACACFNGAS----CDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDP 1056
Query: 1633 ATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPG 1670
+ C EGW L+ +++ +P + + G
Sbjct: 1057 VSGHCACP----------EGWAGLACEKECLPRDVRAG 1084
Score = 86.7 bits (213), Expect = 4e-16
Identities = 68/224 (30%), Positives = 80/224 (35%), Gaps = 60/224 (26%)
Query: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRP-CDC- 1486
F + A+ C C P C P G C C A G C RC G +G P C C C
Sbjct: 1167 FGEDCAQMCQCP---GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYG-PGCEQLCGCL 1222
Query: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQ-TFG--------------CHPL--------- 1522
CD TG C CP + DC L PQ FG C P+
Sbjct: 1223 NGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPG 1282
Query: 1523 ----------------VGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCD-TC 1564
VGCE C+C G+ C +G C C TGR C+ C
Sbjct: 1283 RAGVRCERGCPQNRFGVGCEHTCSCRNGGL-------CHASNGSCSCGLGWTGRHCELAC 1335
Query: 1565 SPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD 1608
PG +G C CH T C+P TG C C G C+
Sbjct: 1336 PPGRYGAACHLECSCHNNST----CEPATGTCRCGPGFYGQACE 1375
Score = 85.1 bits (209), Expect = 1e-15
Identities = 67/235 (28%), Positives = 81/235 (34%), Gaps = 51/235 (21%)
Query: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGF---PNCRPCDCGA 1488
N + C C G C GQC C G DC C G WG C C A
Sbjct: 739 NCSSSCSCG-----GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA 793
Query: 1489 RLCDELTGQCICPPRTIPPDCL-LCQPQTFG--------------CHPLVGCEEC----- 1528
R CD TG C+C P + C +C +G CHP G C
Sbjct: 794 R-CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWT 852
Query: 1529 ---------------NCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR 1573
+CS P +CD SG C C G RC+ P H P
Sbjct: 853 GFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG 912
Query: 1574 C-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCT 1626
C + C C CD ++G C C +G C+ C G F LD + CT
Sbjct: 913 CEQRCQCQHG----AACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCT 963
Score = 79.0 bits (193), Expect = 8e-14
Identities = 66/226 (29%), Positives = 80/226 (35%), Gaps = 25/226 (11%)
Query: 1419 FCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF 1478
FC +A + F + C C G C+ G C C A G C+ +
Sbjct: 942 FCEHACPA-GFFGLDCRSACNC----TAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
Query: 1479 PNC-RPCDC-GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQ 1536
NC + C C CD + GQC C P + P CL P G + C C G
Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPA--GLYGDNCRHSCLCQNGG-- 1052
Query: 1537 ELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTA--PGVCDPLTG 1594
TCD SG C C G C+ PR C +G G+CDP TG
Sbjct: 1053 -----TCDPVSGHCACPEGWAGLACEK-----ECLPRDVRAGCRHSGGCLNGGLCDPHTG 1102
Query: 1595 QCYCKENVQGPKCDQ-CSLGTFSLDAANPKGC-TRCFCFGATERCR 1638
+C C G KC C G F A C C T CR
Sbjct: 1103 RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACR 1148
Score = 78.6 bits (192), Expect = 1e-13
Identities = 146/634 (23%), Positives = 197/634 (31%), Gaps = 151/634 (23%)
Query: 326 HNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCY-------GHATDCYYDPEVDRRR 378
+ T T RCC G+ QQP + ++ EC + C+ G A C+ P R
Sbjct: 100 YTTEARTVLRCCRGWMQQPDEEGCLSA--ECSASLCFHGGRCVPGSAQPCHCPPGFQGPR 157
Query: 379 ASQSLDG--TYQGGGVCIDCQH---HTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCES 433
+D T+ GG CQH +T G C PGF + + C +
Sbjct: 158 CQYDVDECRTHNGG-----CQHRCVNTPGSYLCECKPGFRLHTDS--RTCLAINSCALGN 210
Query: 434 DFTDGTCEDLT---GRCYCRPNF----SGERCDVCAEGFTGFPSCYPTPSSSNDTREQVL 486
C LT RC CRP F G C P + + +
Sbjct: 211 GGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC----------VRRSPCANRNGSCMHRCQ 260
Query: 487 PAGQIVNCDCSAA---GTQGNACR--KDPRVGRCLCKP---NFQGTHCELCAPGFY---- 534
+ C+C G AC + G C N QG+ +C G+
Sbjct: 261 VVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGAD 320
Query: 535 GPGC--------QPCQCSSPGVADDRCDPDTGQ-CRCRVGFE----GATC---DRCAPGY 578
G C C+ ++ G + G C C G+E TC D CA
Sbjct: 321 GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS- 379
Query: 579 FHFPLCQL----------CGCSPAGTLPE---GCDEAGRCLCQPEFAGPHCDR------- 618
P CQ CGC L GC++ C HC
Sbjct: 380 ---PCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQC 436
Query: 619 -CRPGYHGFPNCQACT------CDPRGAL----------------------DQLCGAGGL 649
C GY + + C+ D G L D +
Sbjct: 437 SCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEE 496
Query: 650 CRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC-D 708
R +T T C G + C G C C C TGL C +
Sbjct: 497 AELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNG---GTCLLGLDGCDCPEGWTGLICNE 553
Query: 709 TCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC-DRCKPGFWGLSP 767
TC P + + SC G C C V G +C D C G++G
Sbjct: 554 TCPPDTFGKNCSFSCSCQNGG------TCDSVTGACRCPPGVSGTNCEDGCPKGYYG--- 604
Query: 768 SNPEGC-TRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFG 825
+ C +C+C RG C G C C P + G+ C +C FG G
Sbjct: 605 ---KHCRKKCNCANRG------RCHRLYGACLCDPGLYGRFCHLTCPPWAFGP------G 649
Query: 826 CRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
C S C QSC+ R G C C+ +G C
Sbjct: 650 C-SEECQCVQPHTQSCDKRDGSCSCKAGFRGERC 682
Score = 67.4 bits (163), Expect = 3e-10
Identities = 45/132 (34%), Positives = 54/132 (40%), Gaps = 17/132 (12%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-GARLCDELT 1495
C C G C+P G+C C A G C R C G +G + CDC G CD +T
Sbjct: 1391 CWCQH----GAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVT 1446
Query: 1496 GQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
G C+CPP C L C+ FG + C+C G CD SGQC C
Sbjct: 1447 GLCLCPPGRSGATCNLDCRRGQFGPSCTL---HCDCGGGA-------DCDPVSGQCHCVD 1496
Query: 1555 NVTGRRCDTCSP 1566
G C P
Sbjct: 1497 GYMGPTCREGGP 1508
Score = 60.5 bits (145), Expect = 3e-08
Identities = 47/152 (30%), Positives = 58/152 (38%), Gaps = 28/152 (18%)
Query: 1459 CHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCL-LCQPQTF 1517
C G DCS C C G L G C CP C C P TF
Sbjct: 511 CLDDSFGHDCSL---------TCDDCRNGGTCLLGLDG-CDCPEGWTGLICNETCPPDTF 560
Query: 1518 GCHPLVGCE-ECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFHGYPRCR 1575
G + C C+C G TCD+ +G C+C P V+G C D C G++G +
Sbjct: 561 GKN----CSFSCSCQNGG-------TCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRK 609
Query: 1576 PCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
C+C G C L G C C + G C
Sbjct: 610 KCNCANRGR----CHRLYGACLCDPGLYGRFC 637
Score = 57.8 bits (138), Expect = 2e-07
Identities = 92/365 (25%), Positives = 116/365 (31%), Gaps = 89/365 (24%)
Query: 1831 CLCPASYR----GDSCQ---ECAPGFYRDVKG-LFLGRCVPCQCHGHSD----------- 1871
C C Y+ G +C+ ECA G + G L C CH +
Sbjct: 268 CECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRI 327
Query: 1872 ------RCLPGSGVCVD-CQHNTEGAHCERCQAGFVSSRDDPSA----PCVSCPCPLSVP 1920
C +G C C H + G C C G+ D + C PC V
Sbjct: 328 EMEIVNSCEANNGGCSHGCSHTSAGPLCT-CPRGYELDTDQRTCIDVDDCADSPCCQQVC 386
Query: 1921 SNNFAEGCVLRGGRTQCLCKPGYA----GASCE---RCAPGFFG---NPLVLGSSCQPCD 1970
+NN G +C C GY G CE CA G + L S Q C
Sbjct: 387 TNN--------PGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQ-CS 437
Query: 1971 CSGNGDPNLLFSDCDPLTGACRGC---------LRHTTGPRCEICAPGFYGNALLPGNCT 2021
C + C PL L H + E+ P + +
Sbjct: 438 CEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDEL--PQLFQD-------- 487
Query: 2022 RCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSEC 2081
D E + H L + V C + FG D C C G C
Sbjct: 488 --DDVGADEEEAELRGEHTLTEKFV-------CLDDSFGHDCSLTCDDCR-----NGGTC 533
Query: 2082 HPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQGCR-RCQCP-GGRCDPHTGRCNCPPGLS 2138
C C G G C E C P +G + C C C GG CD TG C CPPG+S
Sbjct: 534 LLGLDGCDCPEGWTGLICNETCPPDTFG---KNCSFSCSCQNGGTCDSVTGACRCPPGVS 590
Query: 2139 GERCD 2143
G C+
Sbjct: 591 GTNCE 595
Score = 51.6 bits (122), Expect = 1e-05
Identities = 39/132 (29%), Positives = 48/132 (36%), Gaps = 25/132 (18%)
Query: 1511 LCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFH 1569
+C +FG + C++C G TC C C TG C +TC P
Sbjct: 510 VCLDDSFGHDCSLTCDDCRNGG---------TCLLGLDGCDCPEGWTGLICNETCPPDTF 560
Query: 1570 GYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-DQCSLGTF------SLDAANP 1622
G C C GT CD +TG C C V G C D C G + + AN
Sbjct: 561 GKNCSFSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR 616
Query: 1623 KGCTR----CFC 1630
C R C C
Sbjct: 617 GRCHRLYGACLC 628
Score = 51.2 bits (121), Expect = 2e-05
Identities = 83/338 (24%), Positives = 113/338 (33%), Gaps = 73/338 (21%)
Query: 1820 GQGALASNVELCLCPASYRGDSCQ----ECAPGFYRDVKGLFLGRCVP------CQC--- 1866
G + + + C CP ++G CQ EC R G RCV C+C
Sbjct: 136 GGRCVPGSAQPCHCPPGFQGPRCQYDVDEC-----RTHNGGCQHRCVNTPGSYLCECKPG 190
Query: 1867 ---HGHSDRCLP------GSGVCV-DCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCP 1916
H S CL G+G C C T H +C+ GF D CV P
Sbjct: 191 FRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQED--GRHCVR-RSP 247
Query: 1917 LSVPSNNFAEGCVLRGGRTQCLCKPGYA----GASCE---RCAPGF--FGNPLVLGSSCQ 1967
+ + + C + G +C C GY G +CE CA G + +
Sbjct: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSF 307
Query: 1968 PCDCSGNGDPNL-----------LFSDCDPLTGAC-RGCLRHTTGPRCEICAPGFYGNAL 2015
C C + + + C+ G C GC + GP C C G+ +
Sbjct: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC-TCPRGYELDTD 366
Query: 2016 LPGNCTRCDC--TPCGTEAC--DPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCA 2071
DC +PC + C +P C C AG DGCG
Sbjct: 367 QRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGY-----------RLSADGCGCEDVDE 415
Query: 2072 CGPAAEGSECH----PQSGQCHCRPG-TMGPQCRECAP 2104
C + G E H S QC C G + R C+P
Sbjct: 416 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSP 453
Score = 44.7 bits (104), Expect = 0.002
Identities = 77/311 (24%), Positives = 103/311 (33%), Gaps = 79/311 (25%)
Query: 1845 CAPGFYR--DVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSS 1902
C G+ + D +G C C H RC+PGS C +G RCQ
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASLCF-HGGRCVPGSAQPCHCPPGFQG---PRCQYDVDEC 165
Query: 1903 RDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVL 1962
R + CV G C CKPG+ L
Sbjct: 166 R---------------THNGGCQHRCVNTPGSYLCECKPGFR-----------------L 193
Query: 1963 GSSCQPCDCSGNGDPNLLFSDCDPLTGACR-GCLRHT-TGPRCEICAPGFYGNALLPGNC 2020
+ + C L + C G C+ C++ T T RC+ C PGF L +
Sbjct: 194 HTDSRTC---------LAINSCALGNGGCQHHCVQLTITRHRCQ-CRPGFQ----LQEDG 239
Query: 2021 TRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGF----DG--CGGCRPCACGP 2074
C C +G C+ + V R RC E H G+ DG C CA G
Sbjct: 240 RHC----VRRSPCANRNGSCMHRCQVV-RGLARC-ECHVGYQLAADGKACEDVDECAAGL 293
Query: 2075 AAEGSECHPQSG--QCHCRPG-TMGPQCRECAPGYWGLPEQGCRRCQCPGGRCD---PHT 2128
A C G +C C G +G R+C + + + C+ G C HT
Sbjct: 294 AQCAHGCLNTQGSFKCVCHAGYELGADGRQC----YRIEMEIVNSCEANNGGCSHGCSHT 349
Query: 2129 GR---CNCPPG 2136
C CP G
Sbjct: 350 SAGPLCTCPRG 360
Score = 43.5 bits (101), Expect = 0.004
Identities = 64/267 (23%), Positives = 83/267 (31%), Gaps = 39/267 (14%)
Query: 618 RCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC--------RCRPGYTGTACQECSPGFH 669
RC G+ P+ + C A LC GG C C PG+ G CQ
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSA--SLCFHGGRCVPGSAQPCHCPPGFQGPRCQY------ 160
Query: 670 GFPSCVPCHCSAEGSLHAACD-PRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPA 728
C G H + P S C C+P G R T C G+
Sbjct: 161 ---DVDECRTHNGGCQHRCVNTPGSYLCECKP---GFRLHTDSRTCLAINSCALGN---G 211
Query: 729 GLAPVDPALPEAQVPCMCR----AHVEGPSCDRCKP-----GFWGLSPSNPEGCTRCSCD 779
G L + C CR +G C R P G G RC C
Sbjct: 212 GCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECH 271
Query: 780 LRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADY-FGCRSCRC-DIGGAL 837
+ L + +C C C + + F + A Y G +C I +
Sbjct: 272 VGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEI 331
Query: 838 GQSCEPRTGVCR--CRPNTQGPTCSEP 862
SCE G C C + GP C+ P
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPLCTCP 358
Score = 40.4 bits (93), Expect = 0.033
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 8/49 (16%)
Query: 2102 CAPGYWGLP-EQGCRRCQCP------GGRCDPHTGR-CNCPPGLSGERC 2142
C G+ P E+GC +C GGRC P + + C+CPPG G RC
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC 158
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 216 bits (550), Expect = 3e-55
Identities = 166/523 (31%), Positives = 207/523 (39%), Gaps = 114/523 (21%)
Query: 377 RRASQSLDGTYQGGGVCI-----DCQH-HTTGVNCERCLPGFYRSP-NHPLDS----PHV 425
RR SQ G Y+ G CI +C H + C PG+ + DS PH
Sbjct: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
Query: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAEGFTGFPSCYPTPSSSNDTREQ 484
RC C++ C +TG C C F G RC+ +CA G G
Sbjct: 143 SNRCQCQNG---ALCNPITGACVCAAGFRGWRCEELCAPGTHG----------------- 182
Query: 485 VLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE-LCAPGFYGPGCQ-PCQ 542
G + C C G +C DPR G CLC P + G +CE LC PG +G C+ C
Sbjct: 183 ---KGCQLPCQCR----HGASC--DPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCP 233
Query: 543 CSSPGVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDE 601
C + G C TG+C C G+ GA C + C PG F Q C C G CD
Sbjct: 234 CQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ----CDH 285
Query: 602 A-GRCLCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
G+C C + G C + C G GF Q C C G GA C C PGY G
Sbjct: 286 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA---CECEPGYKGP 342
Query: 660 ACQE--CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF 717
CQE C G HG +PC C A+ ++ +C P +G C+C+P +G C+ P Y
Sbjct: 343 RCQERLCPEGLHGPGCTLPCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVGYYG 400
Query: 718 PYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR------CKPGFWG------- 764
C Q+PC C+ G C C PGF G
Sbjct: 401 DGC--------------------QLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSC 437
Query: 765 -LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQAD 822
P + CSC+ GT C P G C CK G C C G +GL+ +
Sbjct: 438 AAGTYGPNCSSICSCNNGGT------CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNE 491
Query: 823 YFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
SC C A G +C P G C C P G TC P D
Sbjct: 492 -----SCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPD 525
Score = 199 bits (507), Expect = 3e-50
Identities = 176/592 (29%), Positives = 217/592 (36%), Gaps = 115/592 (19%)
Query: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCP--GFNQQPWKPATANSANECQ 357
C CH H CD QC C G C CP F Q + ++ +C
Sbjct: 275 CPCH-HGGQCDHVTG------QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCS 327
Query: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGT----------------YQGGGVCIDCQHHTT 401
Y P R + L G + G C CQ +
Sbjct: 328 PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACT-CQPGWS 386
Query: 402 GVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV- 460
G +C P Y L C C++ C +TG C C P F GE C V
Sbjct: 387 GHHCNESCPVGYYGDGCQLP-------CTCQNG---ADCHSITGGCTCAPGFMGEVCAVS 436
Query: 461 CAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPN 520
CA G G P+C C C+ GT C P G C CK
Sbjct: 437 CAAGTYG-PNCSSI-------------------CSCNNGGT----C--SPVDGSCTCKEG 470
Query: 521 FQGTHCEL-CAPGFYGPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD-RCAPG 577
+QG C L C G +G C + C C++ G A C P G C C G+ G TC+ C G
Sbjct: 471 WQGLDCTLPCPSGTWGLNCNESCTCAN-GAA---CSPIDGSCSCTPGWLGDTCELPCPDG 526
Query: 578 YFHFPLCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCD-RCRPGYHGFPNCQ-ACTC 634
F + C CS A +GCD G C C + G CD C PG G PNC +C+C
Sbjct: 527 TFGLNCSEHCDCSHA----DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSC 581
Query: 635 DPRGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFHGFPSCVPCHCSAEGSLHAACDPRS 693
+ G+ G C C PG+ G CQ C PGF+G PC S C S
Sbjct: 582 ENGGSCSP---EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSS--RPCHHIS 636
Query: 694 GQCSCRPRVTGLRCD-TCVPGAYNFPYCEAGSCHPAG-LAPVDPALPEAQVPCMCRAHVE 751
G C C P +G C+ C G + + SC G +P+D + C C
Sbjct: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS-------CQCFPGWI 689
Query: 752 GPSCDR-CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS 810
G C + C PGFWG P CSC A C G C C P G C
Sbjct: 690 GKDCSQACPPGFWG-----PACFHACSCH------NGASCSAEDGACHCTPGWTGLFCTQ 738
Query: 811 -CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
C FFG D R C+C G SC+ +G C CR G C +
Sbjct: 739 RCPAAFFGKDCG-----RVCQCQNGA----SCDHISGKCTCRTGFTGQHCEQ 781
Score = 199 bits (506), Expect = 4e-50
Identities = 185/630 (29%), Positives = 234/630 (37%), Gaps = 137/630 (21%)
Query: 296 IGGRCV----CHGH--------ADACDAKDPTDPFRLQCTCQH----NTCGGTCDRCCPG 339
+ GRCV CH + CD+ +C CQ+ N G C C G
Sbjct: 108 VHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACV-CAAG 166
Query: 340 FNQQPWKP----ATANSANECQ-SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCI 394
F + W+ A CQ C C H C DP G C+
Sbjct: 167 F--RGWRCEELCAPGTHGKGCQLPCQCR-HGASC--DPRA----------------GECL 205
Query: 395 DCQHHTTGVNCER-CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNF 453
C TGV CE C PG + + H RC C++ GTC +TG C C P +
Sbjct: 206 -CAPGYTGVYCEELCPPGSHGA--------HCELRCPCQNG---GTCHHITGECACPPGW 253
Query: 454 SGERC-DVCAEGFTG------------------FPSCYPTPSSSNDTREQVLPAGQI--- 491
+G C C G G C+ T D ++ P G
Sbjct: 254 TGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQ 313
Query: 492 --VNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE--LCAPGFYGPGCQ-PCQCSSP 546
+CDC G C P G C C+P ++G C+ LC G +GPGC PC C +
Sbjct: 314 CSQHCDCH----NGGQC--SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDAD 367
Query: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQL-CGCSPAGTLPEGCDE-AGR 604
C P TG C C+ G+ G C+ P ++ CQL C C C G
Sbjct: 368 NTIS--CHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD----CHSITGG 421
Query: 605 CLCQPEFAGPHCD-RCRPGYHGFPNCQA-CTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
C C P F G C C G +G PNC + C+C+ G + G+ C C+ G+ G C
Sbjct: 422 CTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCNNGGTCSPVDGS---CTCKEGWQGLDCT 477
Query: 663 -ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT-CVPGAYNFPYC 720
C G G C C A G AAC P G CSC P G C+ C G +
Sbjct: 478 LPCPSGTWGLNCNESCTC-ANG---AACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS 533
Query: 721 EAGSC-HPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNPEGCTRCSC 778
E C H G PV C C A G CD C PG WG P CSC
Sbjct: 534 EHCDCSHADGCDPVTGH-------CCCLAGWTGIRCDSTCPPGRWG-----PNCSVSCSC 581
Query: 779 DLRGTLGGVAECQPGTGQCFCKPHVCGQACAS-CKDGFFGLDQADYFGCRSCRCDIGGAL 837
+ G+ C P G C C P G C C GF+G GC C +
Sbjct: 582 ENGGS------CSPEDGSCECAPGFRGPLCQRICPPGFYG------HGCAQ-PCPLCVHS 628
Query: 838 GQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
+ C +G+C C P G C++ Y
Sbjct: 629 SRPCHHISGICECLPGFSGALCNQVCAGGY 658
Score = 160 bits (406), Expect = 2e-38
Identities = 125/376 (33%), Positives = 153/376 (40%), Gaps = 78/376 (20%)
Query: 1822 GALASNVE-LCLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGV 1879
GAL + + C+C A +RG C+E CAPG + G +PCQC H C P +G
Sbjct: 151 GALCNPITGACVCAAGFRGWRCEELCAPGTHGK------GCQLPCQCR-HGASCDPRAGE 203
Query: 1880 CVD------------CQHNTEGAHCE---RCQAGFVSSRDDPSAPC--------VSCPCP 1916
C+ C + GAHCE CQ G C + PCP
Sbjct: 204 CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP 263
Query: 1917 LSVPSNNFAEGCVLRGG------RTQCLCKPGYAGASC-ERCAPGFFGNPLVLGSSCQPC 1969
N ++ C G QC C GY G C E C G FG Q C
Sbjct: 264 PGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQHC 318
Query: 1970 DCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCE--ICAPGFYGNALLPGNCTRCDCTP 2027
DC G C P TGAC C GPRC+ +C G +G PG C C
Sbjct: 319 DCHNGG-------QCSPTTGACE-CEPGYKGPRCQERLCPEGLHG----PGCTLPCPCDA 366
Query: 2028 CGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSG 2086
T +C P +G C C+ G +G C + C G++G DGC PC C G++CH +G
Sbjct: 367 DNTISCHPVTGACTCQPGWSGHHCNESCPVGYYG-DGCQ--LPCTC---QNGADCHSITG 420
Query: 2087 QCHCRPGTMGPQCR-ECAPGYWGLPEQGCRR-CQC-PGGRCDPHTGRCNCPPGLSGERCD 2143
C C PG MG C CA G +G C C C GG C P G C C G G C
Sbjct: 421 GCTCAPGFMGEVCAVSCAAGTYG---PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC- 476
Query: 2144 TCSQQHQVPVPGGPVG 2159
+P P G G
Sbjct: 477 ------TLPCPSGTWG 486
Score = 142 bits (359), Expect = 5e-33
Identities = 113/326 (34%), Positives = 141/326 (43%), Gaps = 60/326 (18%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C C A Y GD CQE P G F +C C CH + +C P +G C +C+ +G
Sbjct: 290 CHCTAGYMGDRCQEECPF------GSFGFQCSQHCDCH-NGGQCSPTTGAC-ECEPGYKG 341
Query: 1890 AHCER--CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
C+ C G P + PCP ++N + G C C+PG++G
Sbjct: 342 PRCQERLCPEGL-------HGPGCTLPCPCD--ADNTISCHPVTGA---CTCQPGWSGHH 389
Query: 1948 C-ERCAPGFFGNPLVLGSSCQ-PCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C E C G++G+ CQ PC C NG +DC +TG C C G C +
Sbjct: 390 CNESCPVGYYGD------GCQLPCTCQ-NG------ADCHSITGGCT-CAPGFMGEVCAV 435
Query: 2006 -CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDR-CQEGHFGFDG 2063
CA G YG P + C C GT C P G C CK G G C C G +G +
Sbjct: 436 SCAAGTYG----PNCSSICSCNNGGT--CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLN- 488
Query: 2064 CGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLPEQGC-RRCQCP- 2120
C C C A G+ C P G C C PG +G C C G +GL C C C
Sbjct: 489 CN--ESCTC---ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGL---NCSEHCDCSH 540
Query: 2121 GGRCDPHTGRCNCPPGLSGERCD-TC 2145
CDP TG C C G +G RCD TC
Sbjct: 541 ADGCDPVTGHCCCLAGWTGIRCDSTC 566
Score = 142 bits (357), Expect = 8e-33
Identities = 112/321 (34%), Positives = 137/321 (42%), Gaps = 56/321 (17%)
Query: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRC-VPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C C A + G C P G + C V C C + C P G C +C G
Sbjct: 551 CCCLAGWTGIRCDSTCP------PGRWGPNCSVSCSCE-NGGSCSPEDGSC-ECAPGFRG 602
Query: 1890 AHCER-CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASC 1948
C+R C GF C PCPL V S+ C G +CL PG++GA C
Sbjct: 603 PLCQRICPPGFYGHG------CAQ-PCPLCVHSSR---PCHHISGICECL--PGFSGALC 650
Query: 1949 ER-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC-EIC 2006
+ CA G+FG Q C C+ NG C P+ G+C+ C G C + C
Sbjct: 651 NQVCAGGYFGQ-----DCAQLCSCANNGT-------CSPIDGSCQ-CFPGWIGKDCSQAC 697
Query: 2007 APGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCG 2065
PGF+G A C C +C G C C G TG C RC FG D CG
Sbjct: 698 PPGFWGPACFHA----CSCH--NGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD-CG 750
Query: 2066 GCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQGCRR-CQCPGGR 2123
R C C G+ C SG+C CR G G C + CAPG +G GC++ C+C
Sbjct: 751 --RVCQC---QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECMNNS 802
Query: 2124 -CDPHTGRCNCPPGLSGERCD 2143
CD TG C C PG G RCD
Sbjct: 803 TCDHVTGTCYCSPGFKGIRCD 823
Score = 140 bits (353), Expect = 2e-32
Identities = 113/360 (31%), Positives = 136/360 (37%), Gaps = 64/360 (17%)
Query: 529 CAPGFYGPG--CQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQ- 585
C PG+Y G C P C+ V PDT C C G+ G C P C
Sbjct: 88 CCPGYYESGDFCIPL-CTEECVHGRCVSPDT--CHCEPGWGGPDCSSGCDSDHWGPHCSN 144
Query: 586 LCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDR-CRPGYHGFPNCQ-------ACTCDP 636
C C C+ G C+C F G C+ C PG HG CQ +CDP
Sbjct: 145 RCQCQNGAL----CNPITGACVCAAGFRGWRCEELCAPGTHG-KGCQLPCQCRHGASCDP 199
Query: 637 RGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQ 695
R G C C PGYTG C+E C PG HG + C C G+ H +G+
Sbjct: 200 RA---------GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHI----TGE 246
Query: 696 CSCRPRVTGLRC-DTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPS 754
C+C P TG C C PG + + CH G C C A G
Sbjct: 247 CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCD------HVTGQCHCTAGYMGDR 300
Query: 755 C-DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS--C 811
C + C G +G S C C G +C P TG C C+P G C C
Sbjct: 301 CQEECPFGSFGFQCSQ-----HCDCHNGG------QCSPTTGACECEPGYKGPRCQERLC 349
Query: 812 KDGFFGLDQADYFGCR-SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPD 870
+G G GC C CD + SC P TG C C+P G C+E Y D
Sbjct: 350 PEGLHGP------GCTLPCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVGYYGD 401
Score = 140 bits (352), Expect = 3e-32
Identities = 115/363 (31%), Positives = 142/363 (39%), Gaps = 76/363 (20%)
Query: 1822 GALASNVELCLCPASYRGDSCQE--CAPGFYRDVKGLFLGRCVPCQCHGHSD-RCLPGSG 1878
G + C C Y+G CQE C G + G +PC C + C P +G
Sbjct: 324 GQCSPTTGACECEPGYKGPRCQERLCPEGLHGP------GCTLPCPCDADNTISCHPVTG 377
Query: 1879 VCVDCQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQC 1937
C CQ G HC E C G+ C L N A+ + GG C
Sbjct: 378 ACT-CQPGWSGHHCNESCPVGYYGDG-----------CQLPCTCQNGADCHSITGG---C 422
Query: 1938 LCKPGYAGASCE-RCAPGFFGNPLVL------GSSCQP----CDC--------------S 1972
C PG+ G C CA G +G G +C P C C S
Sbjct: 423 TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPS 482
Query: 1973 GNGDPNLLFS-------DCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTR-C 2023
G N S C P+ G+C C G CE+ C G +G NC+ C
Sbjct: 483 GTWGLNCNESCTCANGAACSPIDGSC-SCTPGWLGDTCELPCPDGTFGL-----NCSEHC 536
Query: 2024 DCTPCGTEACDPHSGHCLCKAGVTGRRCD-RCQEGHFGFDGCGGCRPCACGPAAEGSECH 2082
DC+ + CDP +GHC C AG TG RCD C G +G C C+C G C
Sbjct: 537 DCSHA--DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCS--VSCSC---ENGGSCS 588
Query: 2083 PQSGQCHCRPGTMGPQC-RECAPGYWGLP-EQGCRRCQCPGGRCDPHTGRCNCPPGLSGE 2140
P+ G C C PG GP C R C PG++G Q C C C +G C C PG SG
Sbjct: 589 PEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGA 648
Query: 2141 RCD 2143
C+
Sbjct: 649 LCN 651
Score = 131 bits (330), Expect = 1e-29
Identities = 112/339 (33%), Positives = 137/339 (40%), Gaps = 73/339 (21%)
Query: 1844 ECAPGFYRD--------VKGLFLGRCV-PCQCHGHSDRCLPGSG---VCVDCQHNTEGAH 1891
+C PG+Y + GRCV P CH C PG G C + G H
Sbjct: 87 QCCPGYYESGDFCIPLCTEECVHGRCVSPDTCH-----CEPGWGGPDCSSGCDSDHWGPH 141
Query: 1892 CE---RCQAGFVSSRDDPSAPCVS----CPCPLSVPSNNFAEGCVL----RGGRT----- 1935
C +CQ G + + + C + C +GC L R G +
Sbjct: 142 CSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA 201
Query: 1936 -QCLCKPGYAGASCER-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRG 1993
+CLC PGY G CE C PG G L CQ NG C +TG C
Sbjct: 202 GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQ------NG------GTCHHITGEC-A 248
Query: 1994 CLRHTTGPRC-EICAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRC 2051
C TG C + C PG +G NC++ C C G CD +G C C AG G RC
Sbjct: 249 CPPGWTGAVCAQPCPPGTFGQ-----NCSQDCPCHHGGQ--CDHVTGQCHCTAGYMGDRC 301
Query: 2052 -DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE--CAPGYWG 2108
+ C G FGF C + C C G +C P +G C C PG GP+C+E C G G
Sbjct: 302 QEECPFGSFGFQ-CS--QHCDCH---NGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG 355
Query: 2109 LPEQGCR-RCQCPGGR---CDPHTGRCNCPPGLSGERCD 2143
GC C C C P TG C C PG SG C+
Sbjct: 356 ---PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN 391
Score = 107 bits (267), Expect = 2e-22
Identities = 77/245 (31%), Positives = 99/245 (40%), Gaps = 35/245 (14%)
Query: 1378 VVPENVYSFGYLREEPLDKSYDFISHCAAQGYHIS------PSSSSLFCRNAAASLSLFY 1431
+ P Y G + PL H + +HIS P S C A F
Sbjct: 608 ICPPGFYGHGCAQPCPL------CVHSSRPCHHISGICECLPGFSGALCNQVCAG-GYFG 660
Query: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-GAR 1489
+ A+ C C A TC P G C C IG+DCS+ C G+WG C C
Sbjct: 661 QDCAQLCSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGA 716
Query: 1490 LCDELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG 1548
C G C C P C C FG ++C G Q +CD SG
Sbjct: 717 SCSAEDGACHCTPGWTGLFCTQRCPAAFFG-------KDC---GRVCQCQNGASCDHISG 766
Query: 1549 QCKCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
+C CR TG+ C+ C+PG GY + C+C T CD +TG CYC +G +C
Sbjct: 767 KCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNST----CDHVTGTCYCSPGFKGIRC 822
Query: 1608 DQCSL 1612
DQ +L
Sbjct: 823 DQAAL 827
Score = 100 bits (249), Expect = 3e-20
Identities = 67/195 (34%), Positives = 80/195 (41%), Gaps = 27/195 (13%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC--GARLCDEL 1494
C C G C P G C C A G C CA G G PC C GA CD
Sbjct: 146 CQCQN----GALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGAS-CDPR 200
Query: 1495 TGQCICPPRTIPPDC-LLCQPQTFGCHPLVGCE-ECNCSGPGIQELTDPTCDTDSGQCKC 1552
G+C+C P C LC P + G H CE C C G TC +G+C C
Sbjct: 201 AGECLCAPGYTGVYCEELCPPGSHGAH----CELRCPCQNGG-------TCHHITGECAC 249
Query: 1553 RPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-DQC 1610
P TG C C PG G + C CH G CD +TGQC+C G +C ++C
Sbjct: 250 PPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEEC 305
Query: 1611 SLGTFSLDAANPKGC 1625
G+F + C
Sbjct: 306 PFGSFGFQCSQHCDC 320
Score = 97.8 bits (242), Expect = 2e-19
Identities = 74/233 (31%), Positives = 91/233 (39%), Gaps = 30/233 (12%)
Query: 1403 HCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAH 1462
H G +P C + A+ + N + C C+ G TC P G C C
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAA-GTYGPNCSSICSCNN----GGTCSPVDGSCTCKEG 470
Query: 1463 VIGRDCSR-CATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTIPPDCLL-CQPQTFGC 1519
G DC+ C +G WG C C C + G C C P + C L C TFG
Sbjct: 471 WQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG- 529
Query: 1520 HPLVGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPRCR-P 1576
+ C E C+CS CD +G C C TG RCD TC PG G P C
Sbjct: 530 ---LNCSEHCDCSHAD-------GCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVS 578
Query: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCTRC 1628
C C G+ C P G C C +GP C + C G + A P C C
Sbjct: 579 CSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQP--CPLC 625
Score = 95.5 bits (236), Expect = 9e-19
Identities = 60/179 (33%), Positives = 77/179 (43%), Gaps = 26/179 (14%)
Query: 1437 PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCR---PCDCGARLCD 1492
PC C G +C+P G+C C G C C G G +C PC G C
Sbjct: 188 PCQCRH----GASCDPRAGECLCAPGYTGVYCEELCPPGSHG-AHCELRCPCQNGGT-CH 241
Query: 1493 ELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCK 1551
+TG+C CPP C C P TFG + ++C C G CD +GQC
Sbjct: 242 HITGECACPPGWTGAVCAQPCPPGTFGQNC---SQDCPCHHGG-------QCDHVTGQCH 291
Query: 1552 CRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ 1609
C G RC + C G G+ + CDCH G C P TG C C+ +GP+C +
Sbjct: 292 CTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQ----CSPTTGACECEPGYKGPRCQE 346
Score = 91.7 bits (226), Expect = 1e-17
Identities = 74/238 (31%), Positives = 92/238 (38%), Gaps = 51/238 (21%)
Query: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-G 1487
F N ++ C CH G C+ GQC C A +G C C G +GF + CDC
Sbjct: 267 FGQNCSQDCPCHH----GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHN 322
Query: 1488 ARLCDELTGQCICPP---------RTIP-----PDCLLCQP----QTFGCHPLVGCEEC- 1528
C TG C C P R P P C L P T CHP+ G C
Sbjct: 323 GGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQ 382
Query: 1529 ------NCS--------GPGIQE----LTDPTCDTDSGQCKCRPNVTGRRCD-TCSPGFH 1569
+C+ G G Q C + +G C C P G C +C+ G +
Sbjct: 383 PGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTY 442
Query: 1570 GYPRCRP-CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLGTFSLDAANPKGC 1625
G P C C C+ GT C P+ G C CKE QG C C GT+ L+ C
Sbjct: 443 G-PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTC 495
Score = 91.3 bits (225), Expect = 2e-17
Identities = 87/313 (27%), Positives = 115/313 (36%), Gaps = 40/313 (12%)
Query: 1325 WQGHANASFCPHGY---GCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVPE 1381
W GH CP GY GC+ C+ A HS P ++ V V
Sbjct: 385 WSGHHCNESCPVGYYGDGCQLPCTCQNGA---DCHSITGGCTCAPG----FMGEVCAVSC 437
Query: 1382 NVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASL--SLFYNNGARPCG 1439
++G + I C G SP S C+ L +L +G
Sbjct: 438 AAGTYG--------PNCSSICSCN-NGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLN 488
Query: 1440 CHE--VGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDCG-ARLCDELT 1495
C+E A G C P G C C +G C C G +G CDC A CD +T
Sbjct: 489 CNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVT 548
Query: 1496 GQCICPPRTIPPDC-LLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
G C C C C P +G + V C +C G +C + G C+C P
Sbjct: 549 GHCCCLAGWTGIRCDSTCPPGRWGPNCSVSC---SCENGG-------SCSPEDGSCECAP 598
Query: 1555 NVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSL 1612
G C C PGF+G+ +PC + P C ++G C C G C+Q C+
Sbjct: 599 GFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP--CHHISGICECLPGFSGALCNQVCAG 656
Query: 1613 GTFSLDAANPKGC 1625
G F D A C
Sbjct: 657 GYFGQDCAQLCSC 669
Score = 83.6 bits (205), Expect = 3e-15
Identities = 79/257 (30%), Positives = 94/257 (36%), Gaps = 60/257 (23%)
Query: 1831 CLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDR-CLPGSGVCVDCQHNTE 1888
C C +RG CQ C PGFY G PC HS R C SG+C +C
Sbjct: 594 CECAPGFRGPLCQRICPPGFYGH------GCAQPCPLCVHSSRPCHHISGIC-ECLPGFS 646
Query: 1889 GAHCERCQAGFVSSRD----------------DPSAPCV--------SCPCPLSVPSNNF 1924
GA C + AG +D D S C S CP
Sbjct: 647 GALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC 706
Query: 1925 AEGCVLRGGRT------QCLCKPGYAGASC-ERCAPGFFGNPLVLGSSCQPCDCSGNGDP 1977
C G + C C PG+ G C +RC FFG CQ NG
Sbjct: 707 FHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQ------NG-- 758
Query: 1978 NLLFSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPH 2036
+ CD ++G C C TG CE CAPG +G G C+C T CD
Sbjct: 759 ----ASCDHISGKCT-CRTGFTGQHCEQRCAPGTFGY----GCQQLCECMNNST--CDHV 807
Query: 2037 SGHCLCKAGVTGRRCDR 2053
+G C C G G RCD+
Sbjct: 808 TGTCYCSPGFKGIRCDQ 824
Score = 69.3 bits (168), Expect = 7e-11
Identities = 67/267 (25%), Positives = 85/267 (31%), Gaps = 77/267 (28%)
Query: 618 RCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVP- 676
+C PGY+ + C + C + C C PG+ G C H P C
Sbjct: 87 QCCPGYYESGDFCIPLCTEE-CVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 677 CHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT-CVPGAYNFPYCEAGSCHPAGLAPVDP 735
C C G+L C+P +G C C G RC+ C PG H G
Sbjct: 146 CQCQ-NGAL---CNPITGACVCAAGFRGWRCEELCAPGT-----------HGKG------ 184
Query: 736 ALPEAQVPCMCRAHVEGPSCDR------CKPGFWGLSPSN--PEGCTRCSCDLRGTLGGV 787
Q+PC CR G SCD C PG+ G+ P G C+LR
Sbjct: 185 ----CQLPCQCR---HGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNG 237
Query: 788 AECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGV 847
C TG+C C P G CA
Sbjct: 238 GTCHHITGECACPPGWTGAVCAQ------------------------------------- 260
Query: 848 CRCRPNTQGPTCSEPARDHYLPDLHHL 874
C P T G CS+ H+ H+
Sbjct: 261 -PCPPGTFGQNCSQDCPCHHGGQCDHV 286
Score = 66.6 bits (161), Expect = 4e-10
Identities = 67/246 (27%), Positives = 89/246 (36%), Gaps = 62/246 (25%)
Query: 1797 ALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSC-QECAPGFYRDVKG 1855
AL +Q+ + + + ++ S A G + C C + G C Q C PGF+
Sbjct: 648 ALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPA-- 705
Query: 1856 LFLGRCV-PCQCHGHSDRCLPGSGVCVDCQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSC 1913
C C CH + C G C C G C +RC A F
Sbjct: 706 -----CFHACSCHNGAS-CSAEDGAC-HCTPGWTGLFCTQRCPAAFFGK----------- 747
Query: 1914 PCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQP-CDC 1971
C N A + G +C C+ G+ G CE RCAPG F G CQ C+C
Sbjct: 748 DCGRVCQCQNGASCDHISG---KCTCRTGFTGQHCEQRCAPGTF------GYGCQQLCEC 798
Query: 1972 SGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE 2031
N S CD +TG C C+PGF G RCD E
Sbjct: 799 MNN-------STCDHVTGTC-------------YCSPGFKG--------IRCDQAALMME 830
Query: 2032 ACDPHS 2037
+P++
Sbjct: 831 ELNPYT 836
Score = 60.1 bits (144), Expect = 4e-08
Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 33/153 (21%)
Query: 1469 SRCATGYWGFPN-CRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527
S+C GY+ + C P LC E +C+ R + PD C+P G GC+
Sbjct: 86 SQCCPGYYESGDFCIP------LCTE---ECV-HGRCVSPDTCHCEPGWGGPDCSSGCDS 135
Query: 1528 ----------CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDT-CSPGFHGYPRCRP 1576
C C + C+ +G C C G RC+ C+PG HG P
Sbjct: 136 DHWGPHCSNRCQCQNGAL-------CNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLP 188
Query: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ 1609
C C + CDP G+C C G C++
Sbjct: 189 CQCRHGAS----CDPRAGECLCAPGYTGVYCEE 217
Score = 59.3 bits (142), Expect = 7e-08
Identities = 48/175 (27%), Positives = 66/175 (37%), Gaps = 36/175 (20%)
Query: 308 ACDAKDPTDPFRLQCTCQHNTCGGTCDRCCP-GFNQQPWKPATANSANECQSCNCYGHAT 366
+C P C C G C + CP GF W PA ++ + +C
Sbjct: 668 SCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGF----WGPACFHACSCHNGASCSAEDG 723
Query: 367 DCYYDPEVDRRRASQSLDGTYQG---GGVC-----IDCQHHT---------TGVNCE-RC 408
C+ P +Q + G G VC C H + TG +CE RC
Sbjct: 724 ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRC 783
Query: 409 LPGFYRSPNHPLDSPHVCRR-CNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCA 462
PG + + C++ C C + TC+ +TG CYC P F G RCD A
Sbjct: 784 APGTFG---------YGCQQLCEC---MNNSTCDHVTGTCYCSPGFKGIRCDQAA 826
Score = 43.9 bits (102), Expect = 0.003
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 6/78 (7%)
Query: 1550 CKCRPNVTGRRCDTCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD 1608
C C P G C + H P C C C +C+P+TG C C +G +C+
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGA----LCNPITGACVCAAGFRGWRCE 173
Query: 1609 Q-CSLGTFSLDAANPKGC 1625
+ C+ GT P C
Sbjct: 174 ELCAPGTHGKGCQLPCQC 191
Score = 34.7 bits (78), Expect = 1.8
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
Query: 2094 TMGPQCRECAPGYWGLPEQGCRRC--QCPGGRC-DPHTGRCNCPPGLSGERCDT-CSQQH 2149
TM + +C PGY+ + C +C GRC P T C+C PG G C + C H
Sbjct: 80 TMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDT--CHCEPGWGGPDCSSGCDSDH 137
Query: 2150 QVP 2152
P
Sbjct: 138 WGP 140
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 208 bits (530), Expect = 7e-53
Identities = 161/526 (30%), Positives = 203/526 (38%), Gaps = 120/526 (22%)
Query: 377 RRASQSLDGTYQGGGVCI------------------DCQHHTTGVNCERCLPGFYRSPNH 418
RR SQ G Y+ G +C+ C+ G NC G + P
Sbjct: 89 RRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGP-- 146
Query: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFPSCYPTPSS 477
H RC C++ C +TG C+C F G RC D C +G G
Sbjct: 147 -----HCTSRCQCKNG---ALCNPITGACHCAAGFRGWRCEDRCEQGTYG---------- 188
Query: 478 SNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE-LCAPGFYGP 536
ND ++ C C N D G C C P + G CE LC PG +GP
Sbjct: 189 -NDCHQR---------CQCQ------NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGP 232
Query: 537 GC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGT 594
C Q C C + GV C TG+C C G+ G C + C G F Q C C GT
Sbjct: 233 QCEQRCPCQNGGV----CHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGT 288
Query: 595 LPEGCDEA-GRCLCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRC 652
CD A G+C C P + G C D C G +G + C C G + GA C C
Sbjct: 289 ----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA---CLC 341
Query: 653 RPGYTGTACQE--CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC-DT 709
G+ G C+ C G +G C C E + +C P SG+C+C+P +GL C +T
Sbjct: 342 EAGFAGERCEARLCPEGLYGIKCDKRCPCHLENT--HSCHPMSGECACKPGWSGLYCNET 399
Query: 710 CVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR------CKPGFW 763
C PG Y Q C C+ G CD C PGF
Sbjct: 400 CSPGFYG---------------------EACQQICSCQ---NGADCDSVTGKCTCAPGFK 435
Query: 764 GLSPSNP--EGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQ 820
G+ S P G +C R A C P G C CK G C+ C G +G
Sbjct: 436 GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG--- 492
Query: 821 ADYFGCR-SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
FGC +C+C GGA C G C C P +G C P +D
Sbjct: 493 ---FGCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQD 531
Score = 204 bits (518), Expect = 2e-51
Identities = 173/589 (29%), Positives = 225/589 (38%), Gaps = 134/589 (22%)
Query: 335 RCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQG----- 389
+CCPGF + + + A++C C T C +P S + DG + G
Sbjct: 93 QCCPGFYESG-EMCVPHCADKCVHGRCIAPNT-CQCEPGWGGTNCSSACDGDHWGPHCTS 150
Query: 390 ------GGVC------IDCQHHTTGVNCE-RCLPGFYRSPNHPLDSPHVCRRCNCESDFT 436
G +C C G CE RC G Y + H +RC C++
Sbjct: 151 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCH--------QRCQCQNG-- 200
Query: 437 DGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCD 495
TC+ +TG C C P ++G C D+C G G P C EQ C
Sbjct: 201 -ATCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQC-----------EQ--------RCP 239
Query: 496 CSAAGTQGNACRKDPRVGRCLCKPNFQGTHC-ELCAPGFYGPGC-QPCQCSSPGVADDRC 553
C G + G C C + GT C + C G +G C Q CQC + G C
Sbjct: 240 CQNGGVCHHV------TGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGT----C 289
Query: 554 DPDTGQCRCRVGFEGATC-DRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFA 612
D TGQC C G+ G C D C G + + C C G +G CLC+ FA
Sbjct: 290 DAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH---VSGACLCEAGFA 346
Query: 613 GPHCDR--CRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFH 669
G C+ C G +G + C C G C C+PG++G C E CSPGF+
Sbjct: 347 GERCEARLCPEGLYGIKCDKRCPCHLENT-HSCHPMSGECACKPGWSGLYCNETCSPGFY 405
Query: 670 GFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT-CVPGAYNFPYCEAGSC-HP 727
G C C A CD +G+C+C P G+ C T C G Y C +
Sbjct: 406 GEACQQICSCQNG----ADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKND 461
Query: 728 AGLAPVDPALPEAQVPCMCRAHVEGPSCD-RCKPGFWGLSPSNPEGCT-RCSCDLRGTLG 785
A +PVD + C C+A G C RC G WG GC C C L
Sbjct: 462 AVCSPVDGS-------CTCKAGWHGVDCSIRCPSGTWGF------GCNLTCQC-----LN 503
Query: 786 GVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQADYFGCRS----------CRCDIG 834
G A C G C C P G+ C C+DG +GL+ A+ C CRC G
Sbjct: 504 GGA-CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPG 562
Query: 835 GA------------------------LGQSCEPRTGVCRCRPNTQGPTC 859
+ G SC P G+C C P +G TC
Sbjct: 563 WSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTC 611
Score = 201 bits (512), Expect = 9e-51
Identities = 181/621 (29%), Positives = 235/621 (37%), Gaps = 113/621 (18%)
Query: 301 VCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
+C+ AC +R + C+ T G C + C N T C
Sbjct: 159 LCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE-------CR 211
Query: 361 CYGHATDCY---------YDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPG 411
C T + + P+ ++R Q+ GGVC HH TG C C G
Sbjct: 212 CPPGYTGAFCEDLCPPGKHGPQCEQRCPCQN-------GGVC----HHVTG-ECS-CPSG 258
Query: 412 FYRSP-NHPLDSPHVCRRCNCESD-FTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGF 468
+ + P + C+ E GTC+ TG+C+C P ++GERC D C G G
Sbjct: 259 WMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGV 318
Query: 469 -----------PSCYPTPSS--------SNDTREQVLPAGQI-VNCDCSAAGTQGNACRK 508
CY + ++ P G + CD N
Sbjct: 319 LCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSC 378
Query: 509 DPRVGRCLCKPNFQGTHC-ELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFE 567
P G C CKP + G +C E C+PGFYG CQ CS AD CD TG+C C GF+
Sbjct: 379 HPMSGECACKPGWSGLYCNETCSPGFYGEACQQI-CSCQNGAD--CDSVTGKCTCAPGFK 435
Query: 568 GATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCD-RCRPGYH 624
G C C G + CGC C G C C+ + G C RC G
Sbjct: 436 GIDCSTPCPLGTYGINCSSRCGCKNDAV----CSPVDGSCTCKAGWHGVDCSIRCPSGTW 491
Query: 625 GFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEG 683
GF C C GA + L G C C PG+ G C+ C G +G C CS
Sbjct: 492 GFGCNLTCQCLNGGACNTL---DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCS--- 545
Query: 684 SLHA-ACDPRSGQCSCRPRVTGLRCDT-CVPGAY----NFP-YCEAG-SCHPAGLAPVDP 735
HA C P +G C C P +G+ CD+ C G + + P YC+ G SC P D
Sbjct: 546 --HADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSP------DD 597
Query: 736 ALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGT 794
+ C C G +C R C PGF+G RCS + C T
Sbjct: 598 GI------CECAPGFRGTTCQRICSPGFYG---------HRCSQTCPQCVHSSGPCHHIT 642
Query: 795 GQCFCKPHVCGQACAS-CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPN 853
G C C P G C C G FG + A C C G +C P C+C P
Sbjct: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGI-----CTCTNNG----TCNPIDRSCQCYPG 693
Query: 854 TQGPTCSEPARD-HYLPDLHH 873
G CS+P H+ P+ H
Sbjct: 694 WIGSDCSQPCPPAHWGPNCIH 714
Score = 182 bits (463), Expect = 4e-45
Identities = 177/639 (27%), Positives = 233/639 (36%), Gaps = 130/639 (20%)
Query: 296 IGGRCVCHGH--ADACDAKDPTDPFRLQCT--CQ-HNTCGGTCD------RCCPGFNQQP 344
+ G C C C P F C+ CQ HN GGTCD C PG+ +
Sbjct: 249 VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN--GGTCDAATGQCHCSPGYTGER 306
Query: 345 WK---PATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTT 401
+ P ++C C + CY+ G C+ C+
Sbjct: 307 CQDECPVGTYGVLCAETCQCV-NGGKCYHV------------------SGACL-CEAGFA 346
Query: 402 GVNCER--CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC- 458
G CE C G Y +RC C + T +C ++G C C+P +SG C
Sbjct: 347 GERCEARLCPEGLY--------GIKCDKRCPCHLENTH-SCHPMSGECACKPGWSGLYCN 397
Query: 459 DVCAEGFTGFPSCYPTPSSSN-----DTREQVLPAGQIVNCDCSAA---GTQGNACRK-- 508
+ C+ GF G +C S N + A DCS GT G C
Sbjct: 398 ETCSPGFYG-EACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
Query: 509 --------DPRVGRCLCKPNFQGTHCEL-CAPGFYGPGCQ-PCQCSSPGVADDRCDPDTG 558
P G C CK + G C + C G +G GC CQC + G C+ G
Sbjct: 457 GCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGA----CNTLDG 512
Query: 559 QCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEA-GRCLCQPEFAGPHC 616
C C G+ G C+ C G + + C CS A +GC G C C P ++G HC
Sbjct: 513 TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHA----DGCHPTTGHCRCLPGWSGVHC 568
Query: 617 DR-CRPGYHGFPNCQA-CTCDPRGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFHGFPS 673
D C G G PNC C C + G+C C PG+ GT CQ CSPGF+G
Sbjct: 569 DSVCAEGRWG-PNCSLPCYCKNGASCSP---DDGICECAPGFRGTTCQRICSPGFYGHRC 624
Query: 674 CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCD----------------TCVPGAYNF 717
C S C +G C C P TG C+ TC
Sbjct: 625 SQTCPQCVHSS--GPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCN 682
Query: 718 PYCEAGSCHPAGLA-----PVDPALPEAQVPCMCRAHVEGPSCD------RCKPGFWGLS 766
P + C+P + P PA C H G C +C PG+ GL
Sbjct: 683 PIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCH-NGAFCSAYDGECKCTPGWTGLY 741
Query: 767 PSN--PEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS-CKDGFFGLDQADY 823
+ P G C L A+C +GQC C+ G+ C C G +G
Sbjct: 742 CTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG------ 795
Query: 824 FGCRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
+GCR C C +C+ TG C C P +G C +
Sbjct: 796 YGCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 143 bits (360), Expect = 4e-33
Identities = 115/325 (35%), Positives = 136/325 (41%), Gaps = 61/325 (18%)
Query: 1831 CLCPASYRGDSCQ-ECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C C Y G+ CQ EC G Y G+ CQC + +C SG C+ C+ G
Sbjct: 296 CHCSPGYTGERCQDECPVGTY----GVLCAET--CQCV-NGGKCYHVSGACL-CEAGFAG 347
Query: 1890 AHCER--CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
CE C G + D CPC L C G +C CKPG++G
Sbjct: 348 ERCEARLCPEGLYGIKCDKR-----CPCHLEN-----THSCHPMSG--ECACKPGWSGLY 395
Query: 1948 C-ERCAPGFFGNPLVLGSSCQP-CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
C E C+PGF+G +CQ C C NG +DCD +TG C C G C
Sbjct: 396 CNETCSPGFYGE------ACQQICSCQ-NG------ADCDSVTGKCT-CAPGFKGIDCST 441
Query: 2006 -CAPGFYGNALLPGNCT-RCDCTPCGTEACDPHSGHCLCKAGVTGRRCD-RCQEGHFGFD 2062
C G YG NC+ RC C C P G C CKAG G C RC G +GF
Sbjct: 442 PCPLGTYGI-----NCSSRCGCK--NDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGF- 493
Query: 2063 GCGGCR-PCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLPEQGCRRCQCP 2120
GC C C G C+ G C C PG G +C C G +GL RC C
Sbjct: 494 ---GCNLTCQC---LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGL--NCAERCDCS 545
Query: 2121 -GGRCDPHTGRCNCPPGLSGERCDT 2144
C P TG C C PG SG CD+
Sbjct: 546 HADGCHPTTGHCRCLPGWSGVHCDS 570
Score = 141 bits (355), Expect = 1e-32
Identities = 138/481 (28%), Positives = 170/481 (35%), Gaps = 141/481 (29%)
Query: 295 SIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN 354
S+ G+C C D P C T G C C N P +
Sbjct: 423 SVTGKCTCAPGFKGIDCSTP---------CPLGTYGINCSSRCGCKNDAVCSPVDGSC-- 471
Query: 355 ECQSCNCYGHATDCYY-------------DPEVDRRRASQSLDGT------YQGGGVCID 395
+C H DC + A +LDGT ++G +
Sbjct: 472 ---TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP 528
Query: 396 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSG 455
CQ T G+NC RC+C DG C TG C C P +SG
Sbjct: 529 CQDGTYGLNC--------------------AERCDCSH--ADG-CHPTTGHCRCLPGWSG 565
Query: 456 ERCD-VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGR 514
CD VCAEG G P+C LP C C G +C D G
Sbjct: 566 VHCDSVCAEGRWG-PNCS-------------LP------CYCK----NGASCSPDD--GI 599
Query: 515 CLCKPNFQGTHCE-LCAPGFYGPGC-QPC-QCSSPGVADDRCDPDTGQCRCRVGFEGATC 571
C C P F+GT C+ +C+PGFYG C Q C QC + C TG C C GF GA C
Sbjct: 600 CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH---SSGPCHHITGLCDCLPGFTGALC 656
Query: 572 DR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGR-CLCQPEFAGPHCDRCRPGYHGFPNC 629
+ C G F +C C+ GT C+ R C C P + G C + P H PNC
Sbjct: 657 NEVCPSGRFGKNCAGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNC 712
Query: 630 -QACTCDPRGALDQLCGA-GGLCRCRPGYTGTAC-QECSPGFHGFPSCVPCHCSAEGSL- 685
C C GA C A G C+C PG+TG C Q C GF+G + C C
Sbjct: 713 IHTCNCH-NGAF---CSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCD 768
Query: 686 --------------------------------------HAACDPRSGQCSCRPRVTGLRC 707
++ CD +G C C P G RC
Sbjct: 769 HISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARC 828
Query: 708 D 708
D
Sbjct: 829 D 829
Score = 129 bits (325), Expect = 4e-29
Identities = 127/424 (29%), Positives = 159/424 (37%), Gaps = 114/424 (26%)
Query: 1822 GALASNVE-LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSD-------- 1871
GAL + + C C A +RG C++ R +G + C CQC +
Sbjct: 157 GALCNPITGACHCAAGFRGWRCED------RCEQGTYGNDCHQRCQCQNGATCDHVTGEC 210
Query: 1872 RCLPG--SGVCVD-CQHNTEGAHCER---CQAGFVSSRDDPSAPCVS------C--PCPL 1917
RC PG C D C G CE+ CQ G V C S C PCP
Sbjct: 211 RCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPE 270
Query: 1918 SVPSNNFAEGCVLRGGRT------QCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQPCD 1970
N ++ C G T QC C PGY G C+ C G +G VL + C
Sbjct: 271 GRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYG---VL--CAETCQ 325
Query: 1971 CSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCE--ICAPGFYGNALLPGNCT-RCDCTP 2027
C G C ++GAC C G RCE +C G YG C RC C
Sbjct: 326 CVNGGK-------CYHVSGACL-CEAGFAGERCEARLCPEGLYGI-----KCDKRCPCHL 372
Query: 2028 CGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCG---GCR----------PCACG 2073
T +C P SG C CK G +G C + C G +G + C C+ C C
Sbjct: 373 ENTHSCHPMSGECACKPGWSGLYCNETCSPGFYG-EACQQICSCQNGADCDSVTGKCTCA 431
Query: 2074 PAAEGSE-------------------------CHPQSGQCHCRPGTMGPQCR-ECAPGYW 2107
P +G + C P G C C+ G G C C G W
Sbjct: 432 PGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTW 491
Query: 2108 GLPEQGCR-RCQC-PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHC- 2164
G GC CQC GG C+ G C C PG GE+C ++P G G ++C
Sbjct: 492 GF---GCNLTCQCLNGGACNTLDGTCTCAPGWRGEKC-------ELPCQDGTYG--LNCA 539
Query: 2165 EVCD 2168
E CD
Sbjct: 540 ERCD 543
Score = 127 bits (319), Expect = 2e-28
Identities = 109/358 (30%), Positives = 140/358 (39%), Gaps = 87/358 (24%)
Query: 1831 CLCPASYRGDSCQ-ECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C C +RG+ C+ C G Y L C C H+D C P +G C C G
Sbjct: 514 CTCAPGWRGEKCELPCQDGTYG------LNCAERCDC-SHADGCHPTTGHC-RCLPGWSG 565
Query: 1890 AHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCE 1949
HC+ A + P S PC ++ + + C C PG+ G +C+
Sbjct: 566 VHCDSVCA------EGRWGPNCSLPCYCKNGASCSPDDGI-------CECAPGFRGTTCQ 612
Query: 1950 R-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC-EICA 2007
R C+PGF+G+ +C C S C +TG C CL TG C E+C
Sbjct: 613 RICSPGFYGHRC--SQTCPQCVHSSG--------PCHHITGLC-DCLPGFTGALCNEVCP 661
Query: 2008 PGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRCDR-CQEGHFG----- 2060
G +G NC C CT GT C+P C C G G C + C H+G
Sbjct: 662 SGRFGK-----NCAGICTCTNNGT--CNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIH 714
Query: 2061 ------------FDGCGGCRP----------CACG----------PAAEGSECHPQSGQC 2088
+DG C P C G G++C SGQC
Sbjct: 715 TCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQC 774
Query: 2089 HCRPGTMGPQC-RECAPGYWGLPEQGCRR-CQC-PGGRCDPHTGRCNCPPGLSGERCD 2143
CR G MG C ++C G +G GCR+ C C CD TG C C PG G RCD
Sbjct: 775 TCRTGFMGRHCEQKCPSGTYG---YGCRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
Score = 115 bits (288), Expect = 8e-25
Identities = 81/216 (37%), Positives = 98/216 (45%), Gaps = 35/216 (16%)
Query: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLR 1996
C C+PG+ G +C G P C C NG + C+P+TGAC C
Sbjct: 124 CQCEPGWGGTNCSSACDGDHWGP----HCTSRCQCK-NG------ALCNPITGACH-CAA 171
Query: 1997 HTTGPRCEI-CAPGFYGNALLPGNC-TRCDCTPCGTEACDPHSGHCLCKAGVTGRRC-DR 2053
G RCE C G YGN +C RC C T CD +G C C G TG C D
Sbjct: 172 GFRGWRCEDRCEQGTYGN-----DCHQRCQCQNGAT--CDHVTGECRCPPGYTGAFCEDL 224
Query: 2054 CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQ 2112
C G G C P G CH +G+C C G MG C + C G +G +
Sbjct: 225 CPPGKHGPQCEQRC------PCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG---K 275
Query: 2113 GC-RRCQCP-GGRCDPHTGRCNCPPGLSGERC-DTC 2145
C + CQC GG CD TG+C+C PG +GERC D C
Sbjct: 276 NCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDEC 311
Score = 99.4 bits (246), Expect = 6e-20
Identities = 77/254 (30%), Positives = 96/254 (37%), Gaps = 47/254 (18%)
Query: 1412 SPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-R 1470
+P + C + L + N + CGC C P G C C A G DCS R
Sbjct: 431 APGFKGIDC-STPCPLGTYGINCSSRCGCKN----DAVCSPVDGSCTCKAGWHGVDCSIR 485
Query: 1471 CATGYWGFPNCRPCDC-GARLCDELTGQCICPPRTIPPDCLL-CQPQTFG---------- 1518
C +G WGF C C C+ L G C C P C L CQ T+G
Sbjct: 486 CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCS 545
Query: 1519 ----CHPLVGCEEC--------------------NCSGPGIQELTDPTCDTDSGQCKCRP 1554
CHP G C NCS P + +C D G C+C P
Sbjct: 546 HADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCK-NGASCSPDDGICECAP 604
Query: 1555 NVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSL 1612
G C CSPGF+G+ RC C + + G C +TG C C G C++ C
Sbjct: 605 GFRGTTCQRICSPGFYGH-RCSQT-CPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPS 662
Query: 1613 GTFSLDAANPKGCT 1626
G F + A CT
Sbjct: 663 GRFGKNCAGICTCT 676
Score = 99.4 bits (246), Expect = 6e-20
Identities = 70/223 (31%), Positives = 88/223 (39%), Gaps = 35/223 (15%)
Query: 1403 HCAAQGYHIS------PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQ 1456
H + +HI+ P + C S F N A C C G TC P
Sbjct: 633 HSSGPCHHITGLCDCLPGFTGALCNEVCPS-GRFGKNCAGICTCTNNG----TCNPIDRS 687
Query: 1457 CPCHAHVIGRDCSR-CATGYWGFPNC-RPCDC-GARLCDELTGQCICPPRTIPPDCLLCQ 1513
C C+ IG DCS+ C +WG PNC C+C C G+C C P C
Sbjct: 688 CQCYPGWIGSDCSQPCPPAHWG-PNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRC 746
Query: 1514 PQTF---GCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDT-CSPGFH 1569
P F C + C+ CD SGQC CR GR C+ C G +
Sbjct: 747 PLGFYGKDCALICQCQN------------GADCDHISGQCTCRTGFMGRHCEQKCPSGTY 794
Query: 1570 GYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
GY + CDC T CD +TG CYC +G +CDQ +
Sbjct: 795 GYGCRQICDCLNNST----CDHITGTCYCSPGWKGARCDQAGV 833
Score = 97.4 bits (241), Expect = 2e-19
Identities = 68/211 (32%), Positives = 84/211 (39%), Gaps = 33/211 (15%)
Query: 1447 GPTCEPFGGQCPCHAHVIGRDC-SRCATGYWGFPNCRPCDC-GARLCDELTGQCICPPRT 1504
G C P G C C A G C RC G +G + C C CD +TG+C CPP
Sbjct: 157 GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGY 216
Query: 1505 IPPDCL-LCQPQTFGCHPLVGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC- 1561
C LC P G CE+ C C G+ C +G+C C G C
Sbjct: 217 TGAFCEDLCPPGKHGPQ----CEQRCPCQNGGV-------CHHVTGECSCPSGWMGTVCG 265
Query: 1562 DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-DQCSLGTFSLDAA 1620
C G G + C CH GT CD TGQC+C G +C D+C +GT+ + A
Sbjct: 266 QPCPEGRFGKNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCA 321
Query: 1621 NPKGCTR----------CFCFG--ATERCRS 1639
C C C A ERC +
Sbjct: 322 ETCQCVNGGKCYHVSGACLCEAGFAGERCEA 352
Score = 87.0 bits (214), Expect = 3e-16
Identities = 78/255 (30%), Positives = 101/255 (39%), Gaps = 54/255 (21%)
Query: 1830 LCLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCV----PCQCHGHSDRCLPG-------- 1876
+C C +RG +CQ C+PGFY +CV PC CLPG
Sbjct: 599 ICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNE 658
Query: 1877 -----------SGVCVDCQHNTEGAHCER---CQAGFVSSRDDPSAPCVSCPC-PLSVPS 1921
+G+C C +N +R C G++ S D S PC P + +
Sbjct: 659 VCPSGRFGKNCAGICT-CTNNGTCNPIDRSCQCYPGWIGS--DCSQPCPPAHWGPNCIHT 715
Query: 1922 NNFAEGCVLRGGRTQCLCKPGYAGASC-ERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL 1980
N G +C C PG+ G C +RC GF+G L CQ NG
Sbjct: 716 CNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ------NG----- 764
Query: 1981 FSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSG 2038
+DCD ++G C C G CE C G YG C + CDC T CD +G
Sbjct: 765 -ADCDHISGQCT-CRTGFMGRHCEQKCPSGTYGYG-----CRQICDCLNNST--CDHITG 815
Query: 2039 HCLCKAGVTGRRCDR 2053
C C G G RCD+
Sbjct: 816 TCYCSPGWKGARCDQ 830
Score = 83.2 bits (204), Expect = 4e-15
Identities = 69/221 (31%), Positives = 86/221 (38%), Gaps = 29/221 (13%)
Query: 1446 TGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTI 1505
+G C P H I + +C G WG NC G T +C C
Sbjct: 101 SGEMCVPHCADKCVHGRCIAPNTCQCEPG-WGGTNCSSACDGDHWGPHCTSRCQCK---- 155
Query: 1506 PPDCLLCQPQTFGCHPLVG-----CEE-CNCSGPG------IQELTDPTCDTDSGQCKCR 1553
+ LC P T CH G CE+ C G Q TCD +G+C+C
Sbjct: 156 --NGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCP 213
Query: 1554 PNVTGRRC-DTCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-C 1610
P TG C D C PG HG P+C + C C GVC +TG+C C G C Q C
Sbjct: 214 PGYTGAFCEDLCPPGKHG-PQCEQRCPCQNG----GVCHHVTGECSCPSGWMGTVCGQPC 268
Query: 1611 SLGTFSLDAANPKGC-TRCFCFGATERCR-SSSYTRQEFVD 1649
G F + + C C AT +C S YT + D
Sbjct: 269 PEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQD 309
Score = 79.0 bits (193), Expect = 8e-14
Identities = 64/229 (27%), Positives = 80/229 (34%), Gaps = 53/229 (23%)
Query: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDC-G 1487
F N ++ C CH G TC+ GQC C G C C G +G C C
Sbjct: 273 FGKNCSQECQCHN----GGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVN 328
Query: 1488 ARLCDELTGQCICPPRTIPPDC--LLCQPQTFG----------------CHPLVGCEECN 1529
C ++G C+C C LC +G CHP+ G EC
Sbjct: 329 GGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSG--ECA 386
Query: 1530 C----SGPGIQELTDP-----------------TCDTDSGQCKCRPNVTGRRCDT-CSPG 1567
C SG E P CD+ +G+C C P G C T C G
Sbjct: 387 CKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLG 446
Query: 1568 FHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLGTF 1615
+G C C VC P+ G C CK G C +C GT+
Sbjct: 447 TYGINCSSRCGCKN----DAVCSPVDGSCTCKAGWHGVDCSIRCPSGTW 491
Score = 54.3 bits (129), Expect = 2e-06
Identities = 42/131 (32%), Positives = 51/131 (38%), Gaps = 24/131 (18%)
Query: 2049 RRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPG-YW 2107
RR +C G + + C P G P + C C PG G C G +W
Sbjct: 89 RRKSQCCPGFY--ESGEMCVPHCADKCVHGRCIAPNT--CQCEPGWGGTNCSSACDGDHW 144
Query: 2108 GLPEQGCRRCQCPGGR-CDPHTGRCNCPPGLSGERC-DTCSQQHQVPVPGGPVGHSIH-- 2163
G RCQC G C+P TG C+C G G RC D C Q G G+ H
Sbjct: 145 G--PHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQ--------GTYGNDCHQR 194
Query: 2164 CE-----VCDH 2169
C+ CDH
Sbjct: 195 CQCQNGATCDH 205
Score = 40.4 bits (93), Expect = 0.033
Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 23/130 (17%)
Query: 757 RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFF 816
+C PGF+ C R +C+PG G G C+S DG
Sbjct: 93 QCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWG---------GTNCSSACDG-- 141
Query: 817 GLDQADYFG--CRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHH 873
D++G C S C+C GAL C P TG C C +G C + + H
Sbjct: 142 -----DHWGPHCTSRCQCK-NGAL---CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCH 192
Query: 874 LRLELEEAAT 883
R + + AT
Sbjct: 193 QRCQCQNGAT 202
Score = 40.0 bits (92), Expect = 0.043
Identities = 36/130 (27%), Positives = 48/130 (36%), Gaps = 24/130 (18%)
Query: 1831 CLCPASYRGDSC-QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
C C + G C Q C GFY L CQC +D C SG C C+ G
Sbjct: 731 CKCTPGWTGLYCTQRCPLGFYGKDCALI------CQCQNGAD-CDHISGQCT-CRTGFMG 782
Query: 1890 AHCE-RCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASC 1948
HCE +C +G C++ N+ + C C PG+ GA C
Sbjct: 783 RHCEQKCPSGTYGYGCRQICDCLN---------NSTCDHIT-----GTCYCSPGWKGARC 828
Query: 1949 ERCAPGFFGN 1958
++ GN
Sbjct: 829 DQAGVIIVGN 838
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 204 bits (519), Expect = 1e-51
Identities = 169/576 (29%), Positives = 211/576 (36%), Gaps = 126/576 (21%)
Query: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
RC CHG P DP C C G +CD C + P+T + CQ+
Sbjct: 190 RCQCHGA--------PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPST----HSCQN 237
Query: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
G +Q C G C P + PN
Sbjct: 238 -------------------------GGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPN- 271
Query: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFPSCYPTPSS 477
+ C C + G C+ TG+C C P ++G+RC + C G G C T
Sbjct: 272 ------CSQECRCHNG---GLCDRFTGQCRCAPGYTGDRCREECPVGRFG-QDCAET--- 318
Query: 478 SNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC--ELCAPGFYG 535
CDC+ R P G CLC+ F G C LC GFYG
Sbjct: 319 ----------------CDCAPDA------RCFPANGACLCEHGFTGDRCTDRLCPDGFYG 356
Query: 536 PGCQ-PCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQL-CGCSPAG 593
CQ PC C C P G+C C G+ G C+ P H P CQ C C G
Sbjct: 357 LSCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGG 414
Query: 594 TLPEGCDEAGRCLCQPEFAGPHC-DRCRPGYHGFPNCQA-CTCDPRGALDQLCGAGGLCR 651
+G C C P + GPHC C P +G NC A C+C+ A + G C
Sbjct: 415 VCQA---TSGLCQCAPGYTGPHCASLCPPDTYGV-NCSARCSCENAIACSPIDGE---CV 467
Query: 652 CRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT- 709
C+ G+ C C PG GF C C+ E A C P++G C+C P G C
Sbjct: 468 CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE----AVCSPQTGACTCTPGWHGAHCQLP 523
Query: 710 CVPGAYNFPYCEAGSC-HPAGLAPVDPALPEAQVPCMCRAHVEGPSCD-RCKPGFWGLSP 767
C G + C H G PV C C+A G C C G WG++
Sbjct: 524 CPKGQFGEGCASRCDCDHSDGCDPVHGR-------CQCQAGWMGARCHLSCPEGLWGVNC 576
Query: 768 SNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQADYFGC 826
SN C+C GT C P G C C P G +C SC+ G +G C
Sbjct: 577 SNT-----CTCKNGGT------CLPENGNCVCAPGFRGPSCQRSCQPGRYGKR------C 619
Query: 827 RSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEP 862
C+C A C P G C C GP CS+P
Sbjct: 620 VPCKC----ANHSFCHPSNGTCYCLAGWTGPDCSQP 651
Score = 182 bits (461), Expect = 7e-45
Identities = 154/514 (29%), Positives = 186/514 (36%), Gaps = 137/514 (26%)
Query: 407 RCLPGFYRSPNH--PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAE 463
+C GFY S PL C + G C +C C P + G+ C CA
Sbjct: 89 QCCHGFYESRGFCVPL----------CAQECVHGRCV-APNQCQCVPGWRGDDCSSECAP 137
Query: 464 GFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQG 523
G G P C C C GN DP+ G C C Q
Sbjct: 138 GMWG-PQCDKP-------------------CSC------GNNSSCDPKSGVCSCPSGLQP 171
Query: 524 THC-ELCAPGFYGPGCQ-PCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD--------- 572
+C + C PG+YGP CQ CQC CDP TG C C G +CD
Sbjct: 172 PNCLQPCTPGYYGPACQFRCQCHGAP-----CDPQTGACFCPAERTGPSCDVSCSQGTSG 226
Query: 573 ----------------------RCAPGY------------FHFPLC-QLCGCSPAGTLPE 597
C PG+ FH P C Q C C G
Sbjct: 227 FFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL--- 283
Query: 598 GCDE-AGRCLCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLC-GAGGLCRCRP 654
CD G+C C P + G C + C G G + C C P D C A G C C
Sbjct: 284 -CDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAP----DARCFPANGACLCEH 338
Query: 655 GYTGTACQE--CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVP 712
G+TG C + C GF+G PC C E SL +C P +G+CSC P GL C+ P
Sbjct: 339 GFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL--SCHPMNGECSCLPGWAGLHCNESCP 396
Query: 713 GAYNFPYC-EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC-DRCKPGFWGLSPSNP 770
+ P C E C G+ L C C GP C C P +G++ S
Sbjct: 397 QDTHGPGCQEHCLCLHGGVCQATSGL------CQCAPGYTGPHCASLCPPDTYGVNCS-- 448
Query: 771 EGCTRCSCDLRGTLGGVAECQPGTGQCFCKP-HVCGQACASCKDGFFGLDQADYFGCR-S 828
RCSC+ C P G+C CK G C G +G F C S
Sbjct: 449 ---ARCSCE------NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG------FSCNAS 493
Query: 829 CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEP 862
C+C A C P+TG C C P G C P
Sbjct: 494 CQC----AHEAVCSPQTGACTCTPGWHGAHCQLP 523
Score = 159 bits (403), Expect = 4e-38
Identities = 137/478 (28%), Positives = 178/478 (37%), Gaps = 87/478 (18%)
Query: 306 ADACDAKDPTDPFRLQ--CTCQHNTCGGTC-DRCCPG--FNQQPWKPATANSANECQSCN 360
A+ CD F C C+H G C DR CP + P T + + S +
Sbjct: 316 AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREH---SLS 372
Query: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTT---GVNCE------RCLPG 411
C+ +C P ++S G G CQ H G C+ +C PG
Sbjct: 373 CHPMNGECSCLPGWAGLHCNESCPQDTHGPG----CQEHCLCLHGGVCQATSGLCQCAPG 428
Query: 412 FYRSPNHPLDSP-----HVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGF 465
+ L P + RC+CE+ C + G C C+ + C V C G
Sbjct: 429 YTGPHCASLCPPDTYGVNCSARCSCENAIA---CSPIDGECVCKEGWQRGNCSVPCPPGT 485
Query: 466 TGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTH 525
GF +C+ S C P+ G C C P + G H
Sbjct: 486 WGF------------------------SCNASCQCAHEAVC--SPQTGACTCTPGWHGAH 519
Query: 526 CEL-CAPGFYGPGCQP-CQCSSPGVADDRCDPDTGQCRCRVGFEGATCD-RCAPGYFHFP 582
C+L C G +G GC C C D CDP G+C+C+ G+ GA C C G +
Sbjct: 520 CQLPCPKGQFGEGCASRCDCDH----SDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVN 575
Query: 583 LCQLCGCSPAGT-LPEGCDEAGRCLCQPEFAGPHCDR-CRPGYHGFPNCQACTCDPRGAL 640
C C GT LPE G C+C P F GP C R C+PG +G C C C A
Sbjct: 576 CSNTCTCKNGGTCLPEN----GNCVCAPGFRGPSCQRSCQPGRYG-KRCVPCKC----AN 626
Query: 641 DQLC-GAGGLCRCRPGYTGTAC-QECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSC 698
C + G C C G+TG C Q C PG G C C G+ C P+ G C C
Sbjct: 627 HSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCIC 682
Query: 699 RPRVTGLRC-DTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC 755
TG C + C G + A P P + PE C+C G C
Sbjct: 683 PLGWTGHHCLEGCPLGTFG-----ANCSQPCQCGPGEKCHPETGA-CVCPPGHSGAPC 734
Score = 145 bits (366), Expect = 7e-34
Identities = 114/350 (32%), Positives = 143/350 (40%), Gaps = 73/350 (20%)
Query: 1831 CLCPASYRGDSCQ-ECAPGFYRDVKGLFLGRC-VPCQCHGHSDRCLPGSGVCVDCQHNTE 1888
C C +RGD C ECAPG + +C PC C G++ C P SGVC C +
Sbjct: 120 CQCVPGWRGDDCSSECAPGMWGP-------QCDKPCSC-GNNSSCDPKSGVC-SCPSGLQ 170
Query: 1889 GAHC-ERCQAGFVS-----------SRDDPSAPCVSCPCPLSVPS--------------- 1921
+C + C G+ + DP CP + PS
Sbjct: 171 PPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
Query: 1922 --NNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNL 1979
++ G V + + C C PG+ G C P F P + Q C C G
Sbjct: 231 STHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGL--- 283
Query: 1980 LFSDCDPLTGACRGCLRHTTGPRC-EICAPGFYGNALLPGNCTR-CDCTPCGTEACDPHS 2037
CD TG CR C TG RC E C G +G +C CDC P C P +
Sbjct: 284 ----CDRFTGQCR-CAPGYTGDRCREECPVGRFGQ-----DCAETCDCAP--DARCFPAN 331
Query: 2038 GHCLCKAGVTGRRC-DR-CQEGHFGFDGCGGCR-PCACGPAAEGSECHPQSGQCHCRPGT 2094
G CLC+ G TG RC DR C +G +G C+ PC C CHP +G+C C PG
Sbjct: 332 GACLCEHGFTGDRCTDRLCPDGFYGLS----CQAPCTCD-REHSLSCHPMNGECSCLPGW 386
Query: 2095 MGPQCRECAPGYWGLPEQGCR-RCQC-PGGRCDPHTGRCNCPPGLSGERC 2142
G C E P P GC+ C C GG C +G C C PG +G C
Sbjct: 387 AGLHCNESCPQDTHGP--GCQEHCLCLHGGVCQATSGLCQCAPGYTGPHC 434
Score = 139 bits (350), Expect = 5e-32
Identities = 126/443 (28%), Positives = 163/443 (36%), Gaps = 135/443 (30%)
Query: 1831 CLCPASYRGDSCQE--CAPGFYRDVKGLFLGRCVPCQC-HGHSDRCLPGSGVCV------ 1881
CLC + GD C + C GFY L PC C HS C P +G C
Sbjct: 334 CLCEHGFTGDRCTDRLCPDGFYG------LSCQAPCTCDREHSLSCHPMNGECSCLPGWA 387
Query: 1882 ------DCQHNTEGAHCER---------CQA--GFVSSRDDPSAPCVSCPCPLSVPSNNF 1924
C +T G C+ CQA G + P + CP N
Sbjct: 388 GLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNC 447
Query: 1925 AEGCVLRGGRT------QCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQ---------- 1967
+ C +C+CK G+ +C C PG +G +SCQ
Sbjct: 448 SARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG--FSCNASCQCAHEAVCSPQ 505
Query: 1968 --PCDCS-----------------GNGDPNLLFSD----CDPLTGACRGCLRHTTGPRCE 2004
C C+ G G + D CDP+ G C+ C G RC
Sbjct: 506 TGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQ-CQAGWMGARCH 564
Query: 2005 I-CAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRCDR-CQEGHFGF 2061
+ C G +G NC+ C C GT C P +G+C+C G G C R CQ G +G
Sbjct: 565 LSCPEGLWGV-----NCSNTCTCKNGGT--CLPENGNCVCAPGFRGPSCQRSCQPGRYG- 616
Query: 2062 DGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGL----------- 2109
C PC C A S CHP +G C+C G GP C + C PG+WG
Sbjct: 617 ---KRCVPCKC---ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHG 670
Query: 2110 ----PE----------------QGC----------RRCQC-PGGRCDPHTGRCNCPPGLS 2138
P+ +GC + CQC PG +C P TG C CPPG S
Sbjct: 671 GTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHS 730
Query: 2139 GERCDTCSQQHQVPVPGGPVGHS 2161
G C Q+ +P PV ++
Sbjct: 731 GAPCRIGIQEPFTVMPTTPVAYN 753
Score = 138 bits (348), Expect = 9e-32
Identities = 118/395 (29%), Positives = 145/395 (36%), Gaps = 92/395 (23%)
Query: 1830 LCLCPASYRGDSC-QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVC-------- 1880
+C CP+ + +C Q C PG+Y CQCHG C P +G C
Sbjct: 162 VCSCPSGLQPPNCLQPCTPGYYGPACQF------RCQCHGAP--CDPQTGACFCPAERTG 213
Query: 1881 ----VDCQHNTEGAHC---ERCQAGFVSSRDDPSAPC--------VSCPCPLSVPSNNFA 1925
V C T G C CQ G V S C S PCP N +
Sbjct: 214 PSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCS 273
Query: 1926 EGCVLRGGRT------QCLCKPGYAGASC-ERCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
+ C G QC C PGY G C E C G FG + CDC+ +
Sbjct: 274 QECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQ-----DCAETCDCAPD---- 324
Query: 1979 LLFSDCDPLTGACRGCLRHTTGPRC--EICAPGFYGNALLPGNCTRCDCTPCGTEACDPH 2036
+ C P GAC C TG RC +C GFYG + C C + +C P
Sbjct: 325 ---ARCFPANGACL-CEHGFTGDRCTDRLCPDGFYGLSCQ----APCTCDREHSLSCHPM 376
Query: 2037 SGHCLCKAGVTGRRCDR-CQEGHFGFDGCGGCRP-CACGPAAEGSECHPQSGQCHCRPGT 2094
+G C C G G C+ C + G GC+ C C G C SG C C PG
Sbjct: 377 NGECSCLPGWAGLHCNESCPQDTHG----PGCQEHCLC---LHGGVCQATSGLCQCAPGY 429
Query: 2095 MGPQCRE-CAPGYWGLPEQGCRRCQCPGG-RCDPHTGRC-------------NCPPGLSG 2139
GP C C P +G+ RC C C P G C CPPG G
Sbjct: 430 TGPHCASLCPPDTYGV--NCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG 487
Query: 2140 ERCD-TCSQQHQV---PVPGG----PVGHSIHCEV 2166
C+ +C H+ P G P H HC++
Sbjct: 488 FSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQL 522
Score = 129 bits (324), Expect = 5e-29
Identities = 111/418 (26%), Positives = 154/418 (36%), Gaps = 95/418 (22%)
Query: 289 YSIKDISIGGRCVC-HGHADA-CDAKDPTDPF----RLQCTCQHNTCGGTCD------RC 336
+S+ + G C C G A C+ P D + C C H GG C +C
Sbjct: 369 HSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLH---GGVCQATSGLCQC 425
Query: 337 CPGFNQQPWKPATANSANECQS-CNCYGHATDCYYDPEVDRRRASQSLDGT------YQG 389
PG+ + C S C + +C + A +DG +Q
Sbjct: 426 APGY-----------TGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQR 474
Query: 390 GGVCIDCQHHTTGVNCER------------------CLPGFYRSPNH-PLDSPHVCRRC- 429
G + C T G +C C PG++ + P C
Sbjct: 475 GNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCA 534
Query: 430 -NCESDFTDGTCEDLTGRCYCRPNFSGERCDV-CAEGFTGFPSCYPTPSSSNDTREQVLP 487
C+ D +DG C+ + GRC C+ + G RC + C EG G
Sbjct: 535 SRCDCDHSDG-CDPVHGRCQCQAGWMGARCHLSCPEGLWG-------------------- 573
Query: 488 AGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGCQPCQCSSP 546
VNC + G C P G C+C P F+G C+ C PG YG C PC+C++
Sbjct: 574 ----VNCSNTCTCKNGGTCL--PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANH 627
Query: 547 GVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRC 605
C P G C C G+ G C + C PG++ Q C C GT + G C
Sbjct: 628 SF----CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHP---QDGSC 680
Query: 606 LCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ 662
+C + G HC + C G G Q C C P GA C C PG++G C+
Sbjct: 681 ICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA---CVCPPGHSGAPCR 735
Score = 121 bits (304), Expect = 1e-26
Identities = 80/214 (37%), Positives = 96/214 (44%), Gaps = 37/214 (17%)
Query: 1936 QCLCKPGYAGASCE-RCAPGFFGNPLVLGSSC-QPCDCSGNGDPNLLFSDCDPLTGACRG 1993
QC C PG+ G C CAPG +G C +PC C N S CDP +G C
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWG------PQCDKPCSCGNN-------SSCDPKSGVC-S 164
Query: 1994 CLRHTTGPRC-EICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCD 2052
C P C + C PG+YG P RC C CDP +G C C A TG CD
Sbjct: 165 CPSGLQPPNCLQPCTPGYYG----PACQFRCQCHGA---PCDPQTGACFCPAERTGPSCD 217
Query: 2053 -RCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLP 2110
C +G GF C C G + + G C C PG MG C C G+ G
Sbjct: 218 VSCSQGTSGFF-CPSTHSCQNGGVFQTPQ-----GSCSCPPGWMGTICSLPCPEGFHG-- 269
Query: 2111 EQGC-RRCQCP-GGRCDPHTGRCNCPPGLSGERC 2142
C + C+C GG CD TG+C C PG +G+RC
Sbjct: 270 -PNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRC 302
Score = 105 bits (261), Expect = 1e-21
Identities = 77/222 (34%), Positives = 88/222 (39%), Gaps = 60/222 (27%)
Query: 1456 QCPCHAHVIGRDCS-RCATGYWGFPNC-RPCDCGARL-CDELTGQCICPPRTIPPDCLL- 1511
QC C G DCS CA G WG P C +PC CG CD +G C CP PP+CL
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWG-PQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQP 177
Query: 1512 CQPQTFG-------------CHPLVGCEECNCSGPGIQELTDPTCD-------------- 1544
C P +G C P G C C E T P+CD
Sbjct: 178 CTPGYYGPACQFRCQCHGAPCDPQTGA--CFCPA----ERTGPSCDVSCSQGTSGFFCPS 231
Query: 1545 -----------TDSGQCKCRPNVTGRRCD-TCSPGFHGYPRC-RPCDCHEAGTAPGVCDP 1591
T G C C P G C C GFHG P C + C CH G+CD
Sbjct: 232 THSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-PNCSQECRCHNG----GLCDR 286
Query: 1592 LTGQCYCKENVQGPKC-DQCSLGTFSLDAANPKGC---TRCF 1629
TGQC C G +C ++C +G F D A C RCF
Sbjct: 287 FTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCF 328
Score = 95.1 bits (235), Expect = 1e-18
Identities = 66/209 (31%), Positives = 78/209 (37%), Gaps = 32/209 (15%)
Query: 1435 ARPCGC-HEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDC-GARLC 1491
A C C H G C+P G+C C A +G C C G WG C C C
Sbjct: 534 ASRCDCDHSDG-----CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC 588
Query: 1492 DELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC 1550
G C+C P P C CQP +G C C C+ C +G C
Sbjct: 589 LPENGNCVCAPGFRGPSCQRSCQPGRYGKR----CVPCKCANHSF-------CHPSNGTC 637
Query: 1551 KCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-D 1608
C TG C C PG G + C CH GT C P G C C G C +
Sbjct: 638 YCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLE 693
Query: 1609 QCSLGTFSLDAANPKGCTRCFCFGATERC 1637
C LGTF + + P C G E+C
Sbjct: 694 GCPLGTFGANCSQPCQC------GPGEKC 716
Score = 92.4 bits (228), Expect = 7e-18
Identities = 73/242 (30%), Positives = 90/242 (37%), Gaps = 34/242 (14%)
Query: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGF--PNCRPCDCGARLCDEL 1494
C CH G C+P G C C A G C C+ G GF P+ C G +
Sbjct: 191 CQCH-----GAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGG-VFQTP 244
Query: 1495 TGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
G C CPP + C L P+ F H +EC C G+ CD +GQC+C P
Sbjct: 245 QGSCSCPPGWMGTICSLPCPEGF--HGPNCSQECRCHNGGL-------CDRFTGQCRCAP 295
Query: 1555 NVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKCDQ--C 1610
TG RC + C G G CDC AP C P G C C+ G +C C
Sbjct: 296 GYTGDRCREECPVGRFGQDCAETCDC-----APDARCFPANGACLCEHGFTGDRCTDRLC 350
Query: 1611 SLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQPG 1670
G + L P C R E S E + GW L + PG
Sbjct: 351 PDGFYGLSCQAPCTCDR-------EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPG 403
Query: 1671 TE 1672
+
Sbjct: 404 CQ 405
Score = 87.0 bits (214), Expect = 3e-16
Identities = 56/146 (38%), Positives = 67/146 (45%), Gaps = 17/146 (11%)
Query: 2006 CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCD-RCQEGHFGFDGC 2064
C GFY + G C C C + C C G G C C G +G C
Sbjct: 90 CCHGFYESR---GFCVPLCAQECVHGRCVAPN-QCQCVPGWRGDDCSSECAPGMWG-PQC 144
Query: 2065 GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQGCR-RCQCPGG 2122
+PC+CG S C P+SG C C G P C + C PGY+G C+ RCQC G
Sbjct: 145 D--KPCSCG---NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYG---PACQFRCQCHGA 196
Query: 2123 RCDPHTGRCNCPPGLSGERCD-TCSQ 2147
CDP TG C CP +G CD +CSQ
Sbjct: 197 PCDPQTGACFCPAERTGPSCDVSCSQ 222
Score = 87.0 bits (214), Expect = 3e-16
Identities = 72/233 (30%), Positives = 90/233 (38%), Gaps = 55/233 (23%)
Query: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDC-SRCATGYWGFPNCRPCDC----- 1486
N ++ C CH G C+ F GQC C G C C G +G CDC
Sbjct: 271 NCSQECRCHN----GGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDAR 326
Query: 1487 -----GARLCDE-LTG-QC---ICPPR----TIPPDCLLCQPQTFGCHPLVGCEECNC-- 1530
GA LC+ TG +C +CP + C + + CHP+ G EC+C
Sbjct: 327 CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNG--ECSCLP 384
Query: 1531 ---------------SGPGIQE----LTDPTCDTDSGQCKCRPNVTGRRC-DTCSPGFHG 1570
GPG QE L C SG C+C P TG C C P +G
Sbjct: 385 GWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYG 444
Query: 1571 YPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLGT--FSLDAA 1620
C C A C P+ G+C CKE Q C C GT FS +A+
Sbjct: 445 VNCSARCSCENA----IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNAS 493
Score = 83.2 bits (204), Expect = 4e-15
Identities = 66/231 (28%), Positives = 82/231 (35%), Gaps = 47/231 (20%)
Query: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDCGAR-L 1490
N + C C A C P G+C C +CS C G WGF C C +
Sbjct: 446 NCSARCSCENAIA----CSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAV 501
Query: 1491 CDELTGQCICPPRTIPPDCLLCQPQ---------------TFGCHPLVGCEECNCSGPGI 1535
C TG C C P C L P+ + GC P+ G +C G
Sbjct: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
Query: 1536 Q-ELTDP------------------TCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPRCR 1575
+ L+ P TC ++G C C P G C +C PG +G RC
Sbjct: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG-KRCV 620
Query: 1576 PCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGC 1625
PC C C P G CYC GP C Q C G + + A C
Sbjct: 621 PCKCANHS----FCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQC 667
Score = 72.0 bits (175), Expect = 1e-11
Identities = 65/212 (30%), Positives = 84/212 (39%), Gaps = 40/212 (18%)
Query: 663 ECSPGFH---GFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT-CVPGAYNFP 718
+C GF+ GF CVP A+ +H C QC C P G C + C PG + P
Sbjct: 89 QCCHGFYESRGF--CVPL--CAQECVHGRC-VAPNQCQCVPGWRGDDCSSECAPGMWG-P 142
Query: 719 YCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC-DRCKPGFWGLSPSNPEGCTRCS 777
C+ P P++ V C C + ++ P+C C PG++G P RC
Sbjct: 143 QCDK----PCSCGNNSSCDPKSGV-CSCPSGLQPPNCLQPCTPGYYG-----PACQFRCQ 192
Query: 778 CDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFGCRSCR-CDIGG 835
C A C P TG CFC G +C SC G G F C S C GG
Sbjct: 193 CH-------GAPCDPQTGACFCPAERTGPSCDVSCSQGTSG------FFCPSTHSCQNGG 239
Query: 836 ALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
+ G C C P G CS P + +
Sbjct: 240 VF----QTPQGSCSCPPGWMGTICSLPCPEGF 267
Score = 53.5 bits (127), Expect = 4e-06
Identities = 56/245 (22%), Positives = 74/245 (30%), Gaps = 59/245 (24%)
Query: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC 361
C D CD D DP +C CQ G C CP + W +N+ C
Sbjct: 533 CASRCD-CDHSDGCDPVHGRCQCQAGWMGARCHLSCP---EGLWGVNCSNTCTCKNGGTC 588
Query: 362 YGHATDCYYDPEVDRRRASQSLD-GTYQGGGVCIDCQHHT---------------TGVNC 405
+C P +S G Y V C +H+ TG +C
Sbjct: 589 LPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDC 648
Query: 406 ER-CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAE 463
+ C PG + + + C C GTC G C C ++G C + C
Sbjct: 649 SQPCPPGHW--------GENCAQTCQCHHG---GTCHPQDGSCICPLGWTGHHCLEGCPL 697
Query: 464 GFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQG 523
G G P C C G C P G C+C P G
Sbjct: 698 GTFGANCSQP--------------------CQCGP----GEKCH--PETGACVCPPGHSG 731
Query: 524 THCEL 528
C +
Sbjct: 732 APCRI 736
Score = 53.5 bits (127), Expect = 4e-06
Identities = 31/91 (34%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDCG-ARL 1490
N A+ C CH G TC P G C C G C C G +G +PC CG
Sbjct: 660 NCAQTCQCHH----GGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEK 715
Query: 1491 CDELTGQCICPPRTIPPDCLLCQPQTFGCHP 1521
C TG C+CPP C + + F P
Sbjct: 716 CHPETGACVCPPGHSGAPCRIGIQEPFTVMP 746
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 169,739,596
Number of Sequences: 37866
Number of extensions: 9551165
Number of successful extensions: 51132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 901
Number of HSP's that attempted gapping in prelim test: 29724
Number of HSP's gapped (non-prelim): 8632
length of query: 3695
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3573
effective length of database: 13,627,866
effective search space: 48692365218
effective search space used: 48692365218
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.