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Search of human proteins with 21264355
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264355 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin e1 [Homo sapiens]
(411 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264355 SWI/SNF-related matrix-associated actin-dependent re... 825 0.0
gi|83715964 high-mobility group 20B [Homo sapiens] 66 5e-11
gi|8922633 high-mobility group 20A [Homo sapiens] 62 7e-10
gi|226246533 TOX high mobility group box family member 3 isoform... 61 2e-09
gi|226054295 TOX high mobility group box family member 3 isoform... 61 2e-09
gi|7662274 epidermal Langerhans cell protein LCP1 [Homo sapiens] 59 6e-09
gi|7662322 thymus high mobility group box protein TOX [Homo sapi... 59 8e-09
gi|149408144 TOX high mobility group box family member 2 isoform... 59 8e-09
gi|149408141 TOX high mobility group box family member 2 isoform... 59 8e-09
gi|14249636 TOX high mobility group box family member 2 isoform ... 59 8e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|115529449 upstream binding transcription factor, RNA polymera... 57 3e-08
gi|115529451 upstream binding transcription factor, RNA polymera... 57 3e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 9e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 9e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 55 9e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 55 9e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 55 9e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 55 9e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 55 1e-07
gi|169168462 PREDICTED: similar to high mobility group box 3 [Ho... 55 2e-07
gi|169168166 PREDICTED: similar to high mobility group box 3 [Ho... 55 2e-07
gi|239742753 PREDICTED: similar to high mobility group box 3 iso... 55 2e-07
gi|113416897 PREDICTED: similar to high mobility group box 3 iso... 55 2e-07
gi|71143137 high-mobility group box 3 [Homo sapiens] 55 2e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 54 3e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 54 3e-07
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 54 3e-07
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 54 3e-07
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 53 4e-07
>gi|21264355 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin e1 [Homo sapiens]
Length = 411
Score = 825 bits (2130), Expect = 0.0
Identities = 411/411 (100%), Positives = 411/411 (100%)
Query: 1 MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIP 60
MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIP
Sbjct: 1 MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIP 60
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE
Sbjct: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPD 180
AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPD
Sbjct: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPD 180
Query: 181 DYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRK 240
DYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRK
Sbjct: 181 DYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRK 240
Query: 241 LEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQ 300
LEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQ
Sbjct: 241 LEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQ 300
Query: 301 EEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEG 360
EEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEG
Sbjct: 301 EEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEG 360
Query: 361 TSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
TSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE
Sbjct: 361 TSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
>gi|83715964 high-mobility group 20B [Homo sapiens]
Length = 317
Score = 66.2 bits (160), Expect = 5e-11
Identities = 50/192 (26%), Positives = 82/192 (42%), Gaps = 18/192 (9%)
Query: 63 PKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAE 122
P P P+ Y+R+ + +Q++ +PDL EI K++G W L EKQ YL+E E E
Sbjct: 67 PNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAERE 126
Query: 123 KIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRM---EKGEPYMSIQPAEDP 179
K +Y + ++AY S AY + E+ S + + KG + P
Sbjct: 127 KQQYMKELRAYQQSEAYKMCTEKIQEKKIKKEDSSSGLMNTLLNGHKGGDCDGFSTFDVP 186
Query: 180 DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQR 239
++ A +R ++ +V + VL+R QS+ +
Sbjct: 187 IFTEEFLDQNKAREAELRRLRKM--------------NVAFEEQNAVLQRHTQSMSSARE 232
Query: 240 KLEAELLQIEER 251
+LE E L +EER
Sbjct: 233 RLEQE-LALEER 243
>gi|8922633 high-mobility group 20A [Homo sapiens]
Length = 347
Score = 62.4 bits (150), Expect = 7e-10
Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 31/211 (14%)
Query: 66 PDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIE 125
P PL Y+R+ + +Q++A P++ EI +++G W L EEKQ YL+E + +K
Sbjct: 103 PKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKER 162
Query: 126 YNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDG 185
Y + ++ Y + AY + SR+ Q R +KG+ + + D++
Sbjct: 163 YMKELEQYQKTEAYKVF--------------SRKTQDR-QKGKSHRQDAARQATHDHEKE 207
Query: 186 FSMKHTATARFQRNHRLISEILSESVVPDVR-------SVVTTARMQVLKRQVQSLMVHQ 238
+K + E L+ S + ++ R L++ V+S+
Sbjct: 208 TEVKERSVFDIP---IFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAV 264
Query: 239 RKLEAELLQ------IEERHQEKKRKFLEST 263
KLE +++Q + ++H E R+ L S+
Sbjct: 265 EKLEVDVIQERSRNTVLQQHLETLRQVLTSS 295
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P KP+ Y + R +K NP+ E+ KI+ MW L +E+KQ Y + E
Sbjct: 245 KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTE 304
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRM 164
A K EY +++ AY A + +K+ AE+A + R Q +
Sbjct: 305 AAKKEYLKALAAYR------ASLVSKAAAESAEAQTIRSVQQTL 342
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P KP+ Y + R +K NP+ E+ KI+ MW L +E+KQ Y + E
Sbjct: 250 KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTE 309
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRM 164
A K EY +++ AY A + +K+ AE+A + R Q +
Sbjct: 310 AAKKEYLKALAAYR------ASLVSKAAAESAEAQTIRSVQQTL 347
>gi|7662274 epidermal Langerhans cell protein LCP1 [Homo sapiens]
Length = 621
Score = 59.3 bits (142), Expect = 6e-09
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 8/116 (6%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P KP+ Y + R +K NP+ E+ KI+ MW L +E+KQ Y + E
Sbjct: 218 KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTE 277
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPA 176
A K EY +++ AY + N + +A E S+ P ++ PA
Sbjct: 278 AAKKEYLKALAAYKD--------NQECQATVETVELDPAPPSQTPSPPPMATVDPA 325
>gi|7662322 thymus high mobility group box protein TOX [Homo
sapiens]
Length = 526
Score = 58.9 bits (141), Expect = 8e-09
Identities = 29/82 (35%), Positives = 41/82 (50%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P KP+ Y + R +K NP+ E+ KI+ MW L +E+KQ Y + E
Sbjct: 256 KDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTE 315
Query: 121 AEKIEYNESMKAYHNSPAYLAY 142
A K EY + + AY S +Y
Sbjct: 316 AAKKEYLKQLAAYRASLVSKSY 337
>gi|149408144 TOX high mobility group box family member 2 isoform a
[Homo sapiens]
Length = 506
Score = 58.9 bits (141), Expect = 8e-09
Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 3/127 (2%)
Query: 10 PPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKP 69
PP AT PS+ + R +PG ++ K P P KP
Sbjct: 193 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKK---KKDPNEPQKP 249
Query: 70 LMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNES 129
+ Y + R +K NP ++ KI+ MW L +E+KQ Y + EA K EY ++
Sbjct: 250 VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKA 309
Query: 130 MKAYHNS 136
+ AY S
Sbjct: 310 LAAYRAS 316
>gi|149408141 TOX high mobility group box family member 2 isoform c
[Homo sapiens]
Length = 464
Score = 58.9 bits (141), Expect = 8e-09
Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 3/127 (2%)
Query: 10 PPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKP 69
PP AT PS+ + R +PG ++ K P P KP
Sbjct: 151 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKK---KKDPNEPQKP 207
Query: 70 LMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNES 129
+ Y + R +K NP ++ KI+ MW L +E+KQ Y + EA K EY ++
Sbjct: 208 VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKA 267
Query: 130 MKAYHNS 136
+ AY S
Sbjct: 268 LAAYRAS 274
>gi|14249636 TOX high mobility group box family member 2 isoform c
[Homo sapiens]
Length = 464
Score = 58.9 bits (141), Expect = 8e-09
Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 3/127 (2%)
Query: 10 PPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKP 69
PP AT PS+ + R +PG ++ K P P KP
Sbjct: 151 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKK---KKDPNEPQKP 207
Query: 70 LMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNES 129
+ Y + R +K NP ++ KI+ MW L +E+KQ Y + EA K EY ++
Sbjct: 208 VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKA 267
Query: 130 MKAYHNS 136
+ AY S
Sbjct: 268 LAAYRAS 274
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 58.5 bits (140), Expect = 1e-08
Identities = 65/313 (20%), Positives = 127/313 (40%), Gaps = 25/313 (7%)
Query: 79 KVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQ-----EYLNEYEAEKIEYNESMKAY 133
K+W Q + +LWE K + + + D+E++ E L E E E++ E M
Sbjct: 332 KMWRQEE------RLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQ 384
Query: 134 HNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAED------PDDYDDGFS 187
I + + EE R+++ +M+K E M Q ++ P+ + +
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 188 MKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQ 247
+ + Q I E E + D + + + +++ + E ++
Sbjct: 445 QE-----KMQEQEEKIWE--QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 248 IEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEA 307
E++ +++ + E + + +R+ K E+ E + +EQ +K ++ EK
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 308 AEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDK 367
E+ R + + EEE+ + EEK ++ M +E + E E Q EE E+K
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 368 ESGQEGVDSMAEE 380
QE D M E+
Sbjct: 618 MWEQEEEDKMQEQ 630
Score = 56.6 bits (135), Expect = 4e-08
Identities = 71/344 (20%), Positives = 132/344 (38%), Gaps = 48/344 (13%)
Query: 79 KVWDQVKASNPDLKLWEIGKIIGG---MWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHN 135
K+W+Q K + K+WE + I MW +QE + E E + E E M+
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 136 SPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATAR 195
+ E E++ R R+ E Q E M+ +
Sbjct: 501 K--------MWDQEERMWEQDERLREKEERMREQKKMWQQEE---------KMREEKKTQ 543
Query: 196 FQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEK 255
Q E + RM+ +++++ R+ E ++ + EE+ +E+
Sbjct: 544 EQEKKTWDQE----------EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 256 KRKFLESTDSFNNELKRLCGLKVEV----DMEKIAAEIAQAEEQARKRQEEREKE-AAEQ 310
+ K E + + +++ + ++ + +K+ + EQ K QE+ EK E+
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 311 AERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESG 370
R Q + E+E+ EEK ++ M+ +E + E E + EE E+K G
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713
Query: 371 QE----GVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKK 410
QE G + M E+ E +E + +PE E++
Sbjct: 714 QEEKMWGQEEMREK---------EERIRDQKEKMQERLPEHEER 748
Score = 53.1 bits (126), Expect = 4e-07
Identities = 75/343 (21%), Positives = 133/343 (38%), Gaps = 51/343 (14%)
Query: 79 KVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPA 138
K W Q + KLWE K+ +E++E + E E EKI E M
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKM----------QEQEEKIWEQE-EKIRDQEEMWG------ 470
Query: 139 YLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQR 198
+E+ RQ +M + E M Q + D + + +++
Sbjct: 471 ---------------QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM---WEQ 512
Query: 199 NHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKL--EAELLQIEERHQEKK 256
+ RL + +R + + R+ + ++K + E ++ EER +E++
Sbjct: 513 DERLREK------EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 257 RKFLESTDSFNNELKRLCGL--KVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAE-- 312
+K E + + +++ K+ EK+ + + +EQ K E+ EK ++ E
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
Query: 313 -RSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQ 371
+ Q ++ E+E+ + EEK ++ M +E + E E Q EE E+K GQ
Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686
Query: 372 EGVDSMAEE---GTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
E EE G + G E EE EK+E
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE 729
Score = 48.9 bits (115), Expect = 8e-06
Identities = 43/178 (24%), Positives = 81/178 (45%), Gaps = 15/178 (8%)
Query: 218 VVTTARMQVLKRQVQSLMVHQRKL---EAELLQIEERHQEKKRKFLESTDSFNNELKRLC 274
V T + + RQ + L ++K+ E ++ + EER +E++ K E + + KRL
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Query: 275 GLKVEV--------DMEKIAAEIAQAEEQARK--RQEEREKEAAEQAERSQSSIVPEEEQ 324
+ E+ + +K+ + Q +EQ K QEE+ +E E+ R + + +E+Q
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 325 AANKGEEKKDDENIPMETEE--THLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEE 380
+ ++ +D E E +E EE Q+ E +++E +E M EE
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Score = 40.0 bits (92), Expect = 0.004
Identities = 41/185 (22%), Positives = 78/185 (42%), Gaps = 19/185 (10%)
Query: 201 RLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFL 260
R I E+ E + T + LK++ L R E+E +I+ +E KRK
Sbjct: 159 RYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRK-- 216
Query: 261 ESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARK-----RQEEREKEAAEQAERSQ 315
L+R L +V + E+ + EE+ R+ R++E + E+ R Q
Sbjct: 217 ---------LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267
Query: 316 SSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVD 375
+ E+E+ + E++ ++ + +E L E + ++ E+ E +E E +
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ---MQEQEEKMWEQEE 324
Query: 376 SMAEE 380
M E+
Sbjct: 325 KMREQ 329
Score = 33.1 bits (74), Expect = 0.47
Identities = 62/331 (18%), Positives = 127/331 (38%), Gaps = 42/331 (12%)
Query: 103 MWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQS 162
MWR ++E L E E + E E M+ + E +++ R+++
Sbjct: 257 MWR------QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE 310
Query: 163 RMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTA 222
+M++ E M Q + + + + + R + + E + + R
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEE----RLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 223 RMQVLKRQVQSLMVHQRKL--EAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEV 280
R+ R+ + M Q K+ + E +Q EER +E+++K E ++ + +++ + +
Sbjct: 367 RL----REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 281 ---------------------DMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIV 319
+ EK+ + + EQ K +++ E E+ Q +
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Query: 320 PEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAE 379
+E+Q + EEK D+ M +E + E E + EE E K+ Q+ E
Sbjct: 483 EQEDQMWEQ-EEKMRDQEQKMWDQEERMWEQDERLREKEE--RMREQKKMWQQEEKMREE 539
Query: 380 EGTSDSNTGSESNSATVEEPPTDPIPEDEKK 410
+ T + + + E + + E EKK
Sbjct: 540 KKTQEQEKKTWDQEEKMRE--EERMREREKK 568
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 57.0 bits (136), Expect = 3e-08
Identities = 58/313 (18%), Positives = 145/313 (46%), Gaps = 32/313 (10%)
Query: 56 GITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEY 115
G + K P P KPL PY R+ + + +P++ ++ KI+ +++L +++K +Y
Sbjct: 102 GKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKY 161
Query: 116 LNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQP 175
+ +++ EK E+ ++ + L NAK +++ + ++ Q+ + + Y+ ++P
Sbjct: 162 IQDFQREKQEFERNLARFREDHPDLIQ-NAK-KSDIPEKPKTPQQLWYTHEKKVYLKVRP 219
Query: 176 AEDPDDY----------DDGFSMKHTATARFQRNHRLIS----------EILSESVVPDV 215
E DY ++G + A Q + + ++ ++
Sbjct: 220 DEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANM 279
Query: 216 RSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSF-NNELKRLC 274
+ V +T RM + +Q + ++ Q++ +A + +++ ++ + + L +S E +R+
Sbjct: 280 KDVPSTERMVLCSQQWK--LLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVL 337
Query: 275 GLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKD 334
G + +++ K A ++K +E K +E+ +R S++ E+ + +E++
Sbjct: 338 GEEKMLNINKKQA----TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERP 393
Query: 335 DENIPMETEETHL 347
+ + E+E T L
Sbjct: 394 ELS---ESELTRL 403
Score = 53.1 bits (126), Expect = 4e-07
Identities = 72/366 (19%), Positives = 147/366 (40%), Gaps = 48/366 (13%)
Query: 66 PDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIE 125
P +P+ +S + Q++ P+L E+ +++ MW DL++++K +Y A K +
Sbjct: 370 PKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQ 429
Query: 126 -------YNESMKAYHNSPA-------------YLA-YINAKSRAEAALEEESRQRQSRM 164
E SP YLA + N + +A A+E + M
Sbjct: 430 SERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAME----MTWNNM 485
Query: 165 EKGEPYMSI-QPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTAR 223
EK E M I + AED Y+ S A + ++ + E P + ++
Sbjct: 486 EKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKM--KFQGEPKKPPMNGYQKFSQ 543
Query: 224 MQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDME 283
+ ++ L + +R +++I R Q + E E ++ + +++ ++
Sbjct: 544 ELLSNGELNHLPLKER-----MVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVK 598
Query: 284 KIAAE--IAQAEEQARKRQ--------EEREKEAAEQAERSQSSIVPEEEQAANKGEEKK 333
++ + A E + KR+ + Q++ E+E ++ EE++
Sbjct: 599 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
Query: 334 DDENIPM-----ETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTG 388
DDEN ++ E+ E+ +E EE +D E E D+ +E +S S++
Sbjct: 659 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Query: 389 SESNSA 394
+S+ +
Sbjct: 719 GDSSDS 724
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 57.0 bits (136), Expect = 3e-08
Identities = 58/313 (18%), Positives = 145/313 (46%), Gaps = 32/313 (10%)
Query: 56 GITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEY 115
G + K P P KPL PY R+ + + +P++ ++ KI+ +++L +++K +Y
Sbjct: 102 GKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKY 161
Query: 116 LNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQP 175
+ +++ EK E+ ++ + L NAK +++ + ++ Q+ + + Y+ ++P
Sbjct: 162 IQDFQREKQEFERNLARFREDHPDLIQ-NAK-KSDIPEKPKTPQQLWYTHEKKVYLKVRP 219
Query: 176 AEDPDDY----------DDGFSMKHTATARFQRNHRLIS----------EILSESVVPDV 215
E DY ++G + A Q + + ++ ++
Sbjct: 220 DEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANM 279
Query: 216 RSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSF-NNELKRLC 274
+ V +T RM + +Q + ++ Q++ +A + +++ ++ + + L +S E +R+
Sbjct: 280 KDVPSTERMVLCSQQWK--LLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVL 337
Query: 275 GLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKD 334
G + +++ K A ++K +E K +E+ +R S++ E+ + +E++
Sbjct: 338 GEEKMLNINKKQA----TSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERP 393
Query: 335 DENIPMETEETHL 347
+ + E+E T L
Sbjct: 394 ELS---ESELTRL 403
Score = 53.1 bits (126), Expect = 4e-07
Identities = 72/366 (19%), Positives = 147/366 (40%), Gaps = 48/366 (13%)
Query: 66 PDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIE 125
P +P+ +S + Q++ P+L E+ +++ MW DL++++K +Y A K +
Sbjct: 370 PKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQ 429
Query: 126 -------YNESMKAYHNSPA-------------YLA-YINAKSRAEAALEEESRQRQSRM 164
E SP YLA + N + +A A+E + M
Sbjct: 430 SERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAME----MTWNNM 485
Query: 165 EKGEPYMSI-QPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTAR 223
EK E M I + AED Y+ S A + ++ + E P + ++
Sbjct: 486 EKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKM--KFQGEPKKPPMNGYQKFSQ 543
Query: 224 MQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDME 283
+ ++ L + +R +++I R Q + E E ++ + +++ ++
Sbjct: 544 ELLSNGELNHLPLKER-----MVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVK 598
Query: 284 KIAAE--IAQAEEQARKRQ--------EEREKEAAEQAERSQSSIVPEEEQAANKGEEKK 333
++ + A E + KR+ + Q++ E+E ++ EE++
Sbjct: 599 SLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEE 658
Query: 334 DDENIPM-----ETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTG 388
DDEN ++ E+ E+ +E EE +D E E D+ +E +S S++
Sbjct: 659 DDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Query: 389 SESNSA 394
+S+ +
Sbjct: 719 GDSSDS 724
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 55.5 bits (132), Expect = 9e-08
Identities = 65/311 (20%), Positives = 118/311 (37%), Gaps = 19/311 (6%)
Query: 79 KVWDQVKASNPDLKLWEIGKIIGG---MWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHN 135
K+W+Q K + K+WE + I MW +QE + E E + E E M+
Sbjct: 499 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 558
Query: 136 SPAYLAYINAKSRAEAAL-----------EEESRQRQSRMEKGEPYMSIQPAEDPDDYDD 184
K E EE R+R+ +M + E M Q E + ++
Sbjct: 559 KMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEE 617
Query: 185 GFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAE 244
+ + + E + E Q L Q + L H++ E E
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 245 LLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEERE 304
+Q +E ++ K + T + ++ E M + ++ + EE R QEE+
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR-EQEEKM 736
Query: 305 KEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQ---NGEEGT 361
+E E+ + + + +EE+ + E+ + + +P + E+ E + Q+ EE
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM 796
Query: 362 STPEDKESGQE 372
E+K GQE
Sbjct: 797 RDQEEKMRGQE 807
Score = 49.3 bits (116), Expect = 6e-06
Identities = 67/349 (19%), Positives = 129/349 (36%), Gaps = 39/349 (11%)
Query: 78 RKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSP 137
+K+W Q K + ++WE + D+E++ + E EK + K +
Sbjct: 531 KKMWRQEKMREQEDQMWE-------QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 138 AYLAYINAKSRAEAALEEES--RQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATAR 195
+ R + EEE R+++ +M++ E M Q + + + + +
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 196 FQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEK 255
++ ++ + +P+ + + K Q Q M Q + E ++E++ QE+
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHE----KMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 256 KRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQE------EREKEAAE 309
++K + E R K+ + E + + + +EQ K QE E+E++ E
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 310 QAER--------------------SQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEE 349
Q E+ + + E+E+ EEK + M +E +
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 350 TTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEE 398
E EE E+K GQE EE + G E EE
Sbjct: 820 QEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868
Score = 45.8 bits (107), Expect = 7e-05
Identities = 56/297 (18%), Positives = 126/297 (42%), Gaps = 18/297 (6%)
Query: 79 KVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPA 138
K+W Q + +LWE K + + + D+E++ + E + E E M+
Sbjct: 370 KMWRQEE------RLWEQEKQMREQEQKMRDQEERMW--EQDERLREKEERMREQEKMWE 421
Query: 139 YLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQR 198
+ K R E ++E+ ++ + + EK + I+ E ++ + + Q
Sbjct: 422 QVE----KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477
Query: 199 NHRLISEILS--ESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKL-EAELLQIEERHQEK 255
+ E + +P+ + + + ++ Q + + + K+ + E + +E+ +
Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLW--EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 535
Query: 256 KRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQ 315
+ K E D + +++ + ++ ++ E + +EQ +K ++ EK E+ R +
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERME-KKTQEQEKKTWDQEEKMREEERMRER 594
Query: 316 SSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQE 372
+ EEE+ + EEK ++ M+ +E + E E Q EE E+K QE
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651
Score = 43.9 bits (102), Expect = 3e-04
Identities = 61/294 (20%), Positives = 116/294 (39%), Gaps = 58/294 (19%)
Query: 79 KVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPA 138
K+W+Q + KLWE K+ ++QE + E E EKI E M+
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKM-----------QEQEKMQEQE-EKIWEQEKMEKKTQEQE 700
Query: 139 YLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQR 198
+ K R E E R+R+ +M + E M Q + + + M+ +++
Sbjct: 701 KKTWDQEKMREE----ESMREREKKMREEEEMMREQEEKMQEQEE---KMQEQEEEMWEQ 753
Query: 199 NHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRK 258
++ + E + R L Q + L H++ +Q +E+ E++ K
Sbjct: 754 EEKMWEQ--EEKMWEQQR----------LPEQKEKLWEHEK------MQEQEKIWEQEEK 795
Query: 259 FLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSI 318
+ + + +++ G +E+ + QEE+ E+ + +
Sbjct: 796 MRDQEEKMRGQEEKMRG-----------------QEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 319 VPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQE 372
+EE+ G+E+K +E M+ +E + E E + EE E+K GQE
Sbjct: 839 WGQEEKMW--GQEEKMEEK--MQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 43.5 bits (101), Expect = 3e-04
Identities = 43/200 (21%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 218 VVTTARMQVLKRQVQSLMVHQRKL---EAELLQIEERHQEKKRKFLESTDSFNNELKRLC 274
V T + + RQ + L ++K+ E ++ + EER +E++ K E + + KRL
Sbjct: 265 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLR 324
Query: 275 GLKVEV-DMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKK 333
+ E+ + EK + EQ R++E + + E+ Q + E+E+ + EE+
Sbjct: 325 EQEKELREQEK------ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 334 DDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNS 393
++ M +E + + E +E E++ QE + E+ + +
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 394 ATVEE---PPTDPIPEDEKK 410
+E + I E EKK
Sbjct: 439 TRDQEEKMQEEERIREREKK 458
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/164 (23%), Positives = 78/164 (47%), Gaps = 4/164 (2%)
Query: 207 LSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSF 266
L+ES +++ V + ++ + + V L+ E+ + EE +E+++K + +
Sbjct: 236 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 295
Query: 267 NNELKRLCGL--KVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAE-RSQSSIVPEEE 323
+ +RL K+ EK+ + + EQ ++ +E+ EKE EQ E R Q + E+E
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ-EKELREQKELREQEEQMQEQE 354
Query: 324 QAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDK 367
+ + EEK ++ M +E L E + + E+ E++
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Score = 40.0 bits (92), Expect = 0.004
Identities = 45/186 (24%), Positives = 80/186 (43%), Gaps = 12/186 (6%)
Query: 193 TARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERH 252
+ R ++ R I E+ E + T + LK++ L E+E +I+
Sbjct: 189 STRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNV 248
Query: 253 QEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARK------RQEEREKE 306
+E KRK LE L ++ ++ +M + E+ + E++ RK RQEER +E
Sbjct: 249 KELKRK-LERAKFL---LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLRE 304
Query: 307 AAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPED 366
+ + + +E++ + +E ++ E E +E L E E Q EE E+
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE--LREQEEQMQEQEEKMWEQEE 362
Query: 367 KESGQE 372
K QE
Sbjct: 363 KMREQE 368
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 55.5 bits (132), Expect = 9e-08
Identities = 62/304 (20%), Positives = 119/304 (39%), Gaps = 33/304 (10%)
Query: 110 EEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEP 169
EE EY + +++ IE + L+ I + + + +++ Q+ +G
Sbjct: 315 EEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTK 374
Query: 170 YMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLIS--EILSESVVPDVRSVVTTARMQVL 227
+ + A +Y D ++K +L+ E + + + T R +
Sbjct: 375 W---EMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPI- 430
Query: 228 KRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAA 287
S + + K+EA L+++ + E+ +E T KVE + ++
Sbjct: 431 ---TISSKIQKPKVEAPKLKVQHKFVEE---IIEET-------------KVEDEKSEMEE 471
Query: 288 EIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHL 347
+ E+ +E +KEAAE+ E + EEE AA K K + E E
Sbjct: 472 ALTAITEELAVSMKEEKKEAAEEKEEEPEA--EEEEVAAKKSPVKATAPEVKEEEGEKEE 529
Query: 348 EETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPED 407
EE E ++ +EG + + +E G E +EG+S+ G + T E +
Sbjct: 530 EEGQEEEEEEDEGAKSDQAEEGGSE------KEGSSEKEEGEQEEGETEAEAEGEEAEAK 583
Query: 408 EKKE 411
E+K+
Sbjct: 584 EEKK 587
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/218 (22%), Positives = 93/218 (42%), Gaps = 10/218 (4%)
Query: 200 HRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKF 259
H+ + EI+ E+ V D +S + A + + S+ +++ E + E +E+
Sbjct: 450 HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAK 509
Query: 260 LESTDSFNNELKRLCGLKVEVD------MEKIAAEIAQAEEQARKRQEEREKEAAEQAER 313
+ E+K G K E + E A+ QAEE +++ EKE EQ E
Sbjct: 510 KSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ-EE 568
Query: 314 SQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEG 373
++ E E+A K E+K ++++ + T+E E +++ E +P K +E
Sbjct: 569 GETEAEAEGEEAEAKEEKKVEEKSEEVATKE---ELVADAKVEKPEKAKSPVPKSPVEEK 625
Query: 374 VDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
S + + S + VEE P+P+ +E
Sbjct: 626 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE 663
Score = 43.1 bits (100), Expect = 5e-04
Identities = 86/386 (22%), Positives = 149/386 (38%), Gaps = 53/386 (13%)
Query: 51 VTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDE 110
+T SS I PK P L ++ ++ ++ K + ++ E I E
Sbjct: 430 ITISSKIQKPKVEAPK---LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKE 486
Query: 111 EKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPY 170
EK+E E E E E E A SP K EEE ++ + ++G
Sbjct: 487 EKKEAAEEKEEEP-EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA-- 543
Query: 171 MSIQPAEDPDDYDDGFSMKHT----------------ATARFQRNHRLISEILS--ESVV 212
AE+ +G S K A A+ ++ SE ++ E +V
Sbjct: 544 -KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 602
Query: 213 PDVR-SVVTTARMQVLKRQVQ---------SLMVHQRKLEAELLQIEERHQ--------E 254
D + A+ V K V+ S + + K +EE+ + E
Sbjct: 603 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 662
Query: 255 KKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERS 314
+K K S + K K V+ K AE+ + E++ + +E +E E+ E+
Sbjct: 663 EKGKSPVSKSPVEEKAKSPVP-KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 721
Query: 315 QSSI--VPEEEQAANKGEEKKDDENIPM-ETEETHLEETTESQQNGEEGTSTPEDKESGQ 371
+ VPE+++A + +E+ E + + ++ + HLE+ T+ EEG ++KE +
Sbjct: 722 EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK-----EEGKPLQQEKEKEK 776
Query: 372 EGVDSMAEEGTSDSNT-GSESNSATV 396
G + +EE SD GS V
Sbjct: 777 AGGEGGSEEEGSDKGAKGSRKEDIAV 802
Score = 34.7 bits (78), Expect = 0.16
Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 16/104 (15%)
Query: 278 VEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDEN 337
V+V +EK + +E+ + Q+E+EKE A S EE+ ++KG + E+
Sbjct: 753 VKVHLEK------ETKEEGKPLQQEKEKEKAGGEGGS-------EEEGSDKGAKGSRKED 799
Query: 338 IPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVD-SMAEE 380
I + E EE Q+ E+G+ E+K G+D S A+E
Sbjct: 800 IAVNGEVEGKEEV--EQETKEKGSGREEEKGVVTNGLDLSPADE 841
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 55.5 bits (132), Expect = 9e-08
Identities = 58/282 (20%), Positives = 131/282 (46%), Gaps = 34/282 (12%)
Query: 105 RDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEA-----ALEEESRQ 159
R+ +++K++ E EA K E +++ +S A + AK E AL+EE+R
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQEVTVLKKALDEETRS 1189
Query: 160 RQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVV 219
++++++ M + A+ ++ + A A +N + + + +
Sbjct: 1190 HEAQVQE----MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK----------ENAD 1235
Query: 220 TTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTD---SFNNELKRLCGL 276
++VL + Q + ++KLEA++ +++ + + +R E D NE++ + G+
Sbjct: 1236 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295
Query: 277 KVEVDME--KIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKD 334
E + + K+A ++A Q + QE ++E ++ S EEE+ N +++ D
Sbjct: 1296 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER--NSLQDQLD 1353
Query: 335 DENIPMETEETHLE----ETTESQQNGEEGTSTPEDKESGQE 372
+E + E H+ + ++S++ ++ ST E E G++
Sbjct: 1354 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1395
Score = 46.6 bits (109), Expect = 4e-05
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 34/267 (12%)
Query: 110 EEKQEYLNEYEA---EKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEK 166
+E +E L+E EA E+ + + ++A A ++ + + E EEE+ +++ ++EK
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQ-QMLDLEEQLE---EEEAARQKLQLEK 973
Query: 167 GEPYMSIQPAEDP----DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTA 222
I+ ED DD ++ S + +L+ E +S+
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLS----------KERKLLEERISDLTTNLAEEEEKAK 1023
Query: 223 RMQVLKRQVQSLMVHQRKLEAELLQIEERHQEK---KRKFLESTDSFNNELKRLCGLKVE 279
+ LK + +S++ +LE L + E+ QE KRK F+ ++ L E
Sbjct: 1024 NLTKLKNKHESMI---SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
Query: 280 VDM------EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAA-NKGEEK 332
+ M E++ A +A+ +++ ++ +K + S + E+AA NK E++
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 333 KDDENIPMETEETHLEETTESQQNGEE 359
K D +E +T LE+T +S +E
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQE 1167
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/307 (23%), Positives = 123/307 (40%), Gaps = 57/307 (18%)
Query: 108 TDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKG 167
T +E ++ EA+ ++ E + A + A + + AE S + + EK
Sbjct: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQ-ADLEKEELAEELASSLSGRNALQDEKR 1732
Query: 168 EPYMSIQPAEDPDDYDDGF--SMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQ 225
I E+ + + G +M Q+ +L +E+ +E +AR Q
Sbjct: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE---SARQQ 1789
Query: 226 VLKRQVQSLM--VHQRK-------------LEAELLQIEERHQEKKRKFLESTDSFNNEL 270
L+RQ + L +H+ + LEA++ Q+EE+ +++ R+ +T S +
Sbjct: 1790 -LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 271 KRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGE 330
K+L + ++V+ E+ AE Q +EQA K R K+ Q E ++ EE Q N
Sbjct: 1849 KKLKEILLQVEDERKMAE--QYKEQAEK-GNARVKQLKRQLEEAE-----EESQRINANR 1900
Query: 331 EKKDDENIPMETEETHLEETTESQQ--------------NGEEGTSTPEDKESGQ---EG 373
K E L+E TES + G E + P + G+ E
Sbjct: 1901 RKLQRE----------LDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIEN 1950
Query: 374 VDSMAEE 380
D EE
Sbjct: 1951 ADGSEEE 1957
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 18/138 (13%)
Query: 224 MQVLKRQVQSLMVHQRKLEAELLQIEERHQE--KKRKFLESTDSFNNEL--------KRL 273
MQ + ++Q Q+K E EL ++E++H + +++ L+ EL RL
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 274 CGLKVEVD--MEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEE 331
K E++ + ++ A + + E++ ++ Q ER+K A + + + EEE+AA +
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL---EEEEAA---RQ 967
Query: 332 KKDDENIPMETEETHLEE 349
K E + E + LE+
Sbjct: 968 KLQLEKVTAEAKIKKLED 985
Score = 33.5 bits (75), Expect = 0.36
Identities = 49/259 (18%), Positives = 108/259 (41%), Gaps = 25/259 (9%)
Query: 110 EEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEP 169
++ QE L E +K+ + ++ ++ + L+EE +Q+ +E+
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEE---------RNSLQDQLDEEMEAKQN-LERHIS 1367
Query: 170 YMSIQPAEDP---DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQV 226
++IQ ++ D+ RFQ+ +++ E + T R+Q
Sbjct: 1368 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ- 1426
Query: 227 LKRQVQSLMV---HQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEV-DM 282
+++ L+V +QR+L + L + + + + + + + +E R + E +
Sbjct: 1427 --QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA---EAEAREK 1481
Query: 283 EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMET 342
E A +A+A E+A + +EE E+ + + +++ N E +K + +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 343 EE--THLEETTESQQNGEE 359
EE T LEE + Q E+
Sbjct: 1542 EEMKTQLEELEDELQATED 1560
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 55.5 bits (132), Expect = 9e-08
Identities = 58/282 (20%), Positives = 131/282 (46%), Gaps = 34/282 (12%)
Query: 105 RDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEA-----ALEEESRQ 159
R+ +++K++ E EA K E +++ +S A + AK E AL+EE+R
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQEVTVLKKALDEETRS 1196
Query: 160 RQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVV 219
++++++ M + A+ ++ + A A +N + + + +
Sbjct: 1197 HEAQVQE----MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK----------ENAD 1242
Query: 220 TTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTD---SFNNELKRLCGL 276
++VL + Q + ++KLEA++ +++ + + +R E D NE++ + G+
Sbjct: 1243 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1302
Query: 277 KVEVDME--KIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKD 334
E + + K+A ++A Q + QE ++E ++ S EEE+ N +++ D
Sbjct: 1303 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER--NSLQDQLD 1360
Query: 335 DENIPMETEETHLE----ETTESQQNGEEGTSTPEDKESGQE 372
+E + E H+ + ++S++ ++ ST E E G++
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402
Score = 46.6 bits (109), Expect = 4e-05
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 34/267 (12%)
Query: 110 EEKQEYLNEYEA---EKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEK 166
+E +E L+E EA E+ + + ++A A ++ + + E EEE+ +++ ++EK
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQ-QMLDLEEQLE---EEEAARQKLQLEK 980
Query: 167 GEPYMSIQPAEDP----DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTA 222
I+ ED DD ++ S + +L+ E +S+
Sbjct: 981 VTAEAKIKKLEDEILVMDDQNNKLS----------KERKLLEERISDLTTNLAEEEEKAK 1030
Query: 223 RMQVLKRQVQSLMVHQRKLEAELLQIEERHQEK---KRKFLESTDSFNNELKRLCGLKVE 279
+ LK + +S++ +LE L + E+ QE KRK F+ ++ L E
Sbjct: 1031 NLTKLKNKHESMI---SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1087
Query: 280 VDM------EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAA-NKGEEK 332
+ M E++ A +A+ +++ ++ +K + S + E+AA NK E++
Sbjct: 1088 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1147
Query: 333 KDDENIPMETEETHLEETTESQQNGEE 359
K D +E +T LE+T +S +E
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQE 1174
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/307 (23%), Positives = 123/307 (40%), Gaps = 57/307 (18%)
Query: 108 TDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKG 167
T +E ++ EA+ ++ E + A + A + + AE S + + EK
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQ-ADLEKEELAEELASSLSGRNALQDEKR 1739
Query: 168 EPYMSIQPAEDPDDYDDGF--SMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQ 225
I E+ + + G +M Q+ +L +E+ +E +AR Q
Sbjct: 1740 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE---SARQQ 1796
Query: 226 VLKRQVQSLM--VHQRK-------------LEAELLQIEERHQEKKRKFLESTDSFNNEL 270
L+RQ + L +H+ + LEA++ Q+EE+ +++ R+ +T S +
Sbjct: 1797 -LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 271 KRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGE 330
K+L + ++V+ E+ AE Q +EQA K R K+ Q E ++ EE Q N
Sbjct: 1856 KKLKEILLQVEDERKMAE--QYKEQAEK-GNARVKQLKRQLEEAE-----EESQRINANR 1907
Query: 331 EKKDDENIPMETEETHLEETTESQQ--------------NGEEGTSTPEDKESGQ---EG 373
K E L+E TES + G E + P + G+ E
Sbjct: 1908 RKLQRE----------LDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIEN 1957
Query: 374 VDSMAEE 380
D EE
Sbjct: 1958 ADGSEEE 1964
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 18/138 (13%)
Query: 224 MQVLKRQVQSLMVHQRKLEAELLQIEERHQE--KKRKFLESTDSFNNEL--------KRL 273
MQ + ++Q Q+K E EL ++E++H + +++ L+ EL RL
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 274 CGLKVEVD--MEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEE 331
K E++ + ++ A + + E++ ++ Q ER+K A + + + EEE+AA +
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL---EEEEAA---RQ 974
Query: 332 KKDDENIPMETEETHLEE 349
K E + E + LE+
Sbjct: 975 KLQLEKVTAEAKIKKLED 992
Score = 33.5 bits (75), Expect = 0.36
Identities = 49/259 (18%), Positives = 108/259 (41%), Gaps = 25/259 (9%)
Query: 110 EEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEP 169
++ QE L E +K+ + ++ ++ + L+EE +Q+ +E+
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEE---------RNSLQDQLDEEMEAKQN-LERHIS 1374
Query: 170 YMSIQPAEDP---DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQV 226
++IQ ++ D+ RFQ+ +++ E + T R+Q
Sbjct: 1375 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ- 1433
Query: 227 LKRQVQSLMV---HQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEV-DM 282
+++ L+V +QR+L + L + + + + + + + +E R + E +
Sbjct: 1434 --QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA---EAEAREK 1488
Query: 283 EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMET 342
E A +A+A E+A + +EE E+ + + +++ N E +K + +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 343 EE--THLEETTESQQNGEE 359
EE T LEE + Q E+
Sbjct: 1549 EEMKTQLEELEDELQATED 1567
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 55.5 bits (132), Expect = 9e-08
Identities = 58/282 (20%), Positives = 131/282 (46%), Gaps = 34/282 (12%)
Query: 105 RDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEA-----ALEEESRQ 159
R+ +++K++ E EA K E +++ +S A + AK E AL+EE+R
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQEVTVLKKALDEETRS 1196
Query: 160 RQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVV 219
++++++ M + A+ ++ + A A +N + + + +
Sbjct: 1197 HEAQVQE----MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK----------ENAD 1242
Query: 220 TTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTD---SFNNELKRLCGL 276
++VL + Q + ++KLEA++ +++ + + +R E D NE++ + G+
Sbjct: 1243 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1302
Query: 277 KVEVDME--KIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKD 334
E + + K+A ++A Q + QE ++E ++ S EEE+ N +++ D
Sbjct: 1303 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER--NSLQDQLD 1360
Query: 335 DENIPMETEETHLE----ETTESQQNGEEGTSTPEDKESGQE 372
+E + E H+ + ++S++ ++ ST E E G++
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402
Score = 46.6 bits (109), Expect = 4e-05
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 34/267 (12%)
Query: 110 EEKQEYLNEYEA---EKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEK 166
+E +E L+E EA E+ + + ++A A ++ + + E EEE+ +++ ++EK
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQ-QMLDLEEQLE---EEEAARQKLQLEK 980
Query: 167 GEPYMSIQPAEDP----DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTA 222
I+ ED DD ++ S + +L+ E +S+
Sbjct: 981 VTAEAKIKKLEDEILVMDDQNNKLS----------KERKLLEERISDLTTNLAEEEEKAK 1030
Query: 223 RMQVLKRQVQSLMVHQRKLEAELLQIEERHQEK---KRKFLESTDSFNNELKRLCGLKVE 279
+ LK + +S++ +LE L + E+ QE KRK F+ ++ L E
Sbjct: 1031 NLTKLKNKHESMI---SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1087
Query: 280 VDM------EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAA-NKGEEK 332
+ M E++ A +A+ +++ ++ +K + S + E+AA NK E++
Sbjct: 1088 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1147
Query: 333 KDDENIPMETEETHLEETTESQQNGEE 359
K D +E +T LE+T +S +E
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQE 1174
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/265 (23%), Positives = 112/265 (42%), Gaps = 40/265 (15%)
Query: 108 TDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKG 167
T +E ++ EA+ ++ E + A + A + + AE S + + EK
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQ-ADLEKEELAEELASSLSGRNALQDEKR 1739
Query: 168 EPYMSIQPAEDPDDYDDGF--SMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQ 225
I E+ + + G +M Q+ +L +E+ +E +AR Q
Sbjct: 1740 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE---SARQQ 1796
Query: 226 VLKRQVQSLM--VHQRK-------------LEAELLQIEERHQEKKRKFLESTDSFNNEL 270
L+RQ + L +H+ + LEA++ Q+EE+ +++ R+ +T S +
Sbjct: 1797 -LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
Query: 271 KRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGE 330
K+L + ++V+ E+ AE Q +EQA K R K+ Q E ++ EE Q N
Sbjct: 1856 KKLKEILLQVEDERKMAE--QYKEQAEK-GNARVKQLKRQLEEAE-----EESQRINANR 1907
Query: 331 EKKDDENIPMETEETHLEETTESQQ 355
K E L+E TES +
Sbjct: 1908 RKLQRE----------LDEATESNE 1922
Score = 40.4 bits (93), Expect = 0.003
Identities = 42/198 (21%), Positives = 84/198 (42%), Gaps = 19/198 (9%)
Query: 197 QRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKK 256
+R R ++ + + D++ + A + R+ + RKL+A++ + ++ +
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE--EAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 257 RKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQS 316
E + K+ L E D+ ++ ++A AE +ARK+ + ++E AE+ S S
Sbjct: 1673 ASRDEIFATAKENEKKAKSL--EADLMQLQEDLAAAE-RARKQADLEKEELAEELASSLS 1729
Query: 317 SIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDS 376
G DE +E LEE E +Q E S K + Q +
Sbjct: 1730 ------------GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ--AEQ 1775
Query: 377 MAEEGTSDSNTGSESNSA 394
++ E ++ +T ++ SA
Sbjct: 1776 LSNELATERSTAQKNESA 1793
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 18/138 (13%)
Query: 224 MQVLKRQVQSLMVHQRKLEAELLQIEERHQE--KKRKFLESTDSFNNEL--------KRL 273
MQ + ++Q Q+K E EL ++E++H + +++ L+ EL RL
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 274 CGLKVEVD--MEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEE 331
K E++ + ++ A + + E++ ++ Q ER+K A + + + EEE+AA +
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL---EEEEAA---RQ 974
Query: 332 KKDDENIPMETEETHLEE 349
K E + E + LE+
Sbjct: 975 KLQLEKVTAEAKIKKLED 992
Score = 33.5 bits (75), Expect = 0.36
Identities = 49/259 (18%), Positives = 108/259 (41%), Gaps = 25/259 (9%)
Query: 110 EEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEP 169
++ QE L E +K+ + ++ ++ + L+EE +Q+ +E+
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEE---------RNSLQDQLDEEMEAKQN-LERHIS 1374
Query: 170 YMSIQPAEDP---DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQV 226
++IQ ++ D+ RFQ+ +++ E + T R+Q
Sbjct: 1375 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ- 1433
Query: 227 LKRQVQSLMV---HQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEV-DM 282
+++ L+V +QR+L + L + + + + + + + +E R + E +
Sbjct: 1434 --QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA---EAEAREK 1488
Query: 283 EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMET 342
E A +A+A E+A + +EE E+ + + +++ N E +K + +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 343 EE--THLEETTESQQNGEE 359
EE T LEE + Q E+
Sbjct: 1549 EEMKTQLEELEDELQATED 1567
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 55.5 bits (132), Expect = 9e-08
Identities = 58/282 (20%), Positives = 131/282 (46%), Gaps = 34/282 (12%)
Query: 105 RDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEA-----ALEEESRQ 159
R+ +++K++ E EA K E +++ +S A + AK E AL+EE+R
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTL----DSTATQQELRAKREQEVTVLKKALDEETRS 1189
Query: 160 RQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVV 219
++++++ M + A+ ++ + A A +N + + + +
Sbjct: 1190 HEAQVQE----MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK----------ENAD 1235
Query: 220 TTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTD---SFNNELKRLCGL 276
++VL + Q + ++KLEA++ +++ + + +R E D NE++ + G+
Sbjct: 1236 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295
Query: 277 KVEVDME--KIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKD 334
E + + K+A ++A Q + QE ++E ++ S EEE+ N +++ D
Sbjct: 1296 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER--NSLQDQLD 1353
Query: 335 DENIPMETEETHLE----ETTESQQNGEEGTSTPEDKESGQE 372
+E + E H+ + ++S++ ++ ST E E G++
Sbjct: 1354 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1395
Score = 46.6 bits (109), Expect = 4e-05
Identities = 60/267 (22%), Positives = 118/267 (44%), Gaps = 34/267 (12%)
Query: 110 EEKQEYLNEYEA---EKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEK 166
+E +E L+E EA E+ + + ++A A ++ + + E EEE+ +++ ++EK
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQ-QMLDLEEQLE---EEEAARQKLQLEK 973
Query: 167 GEPYMSIQPAEDP----DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTA 222
I+ ED DD ++ S + +L+ E +S+
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLS----------KERKLLEERISDLTTNLAEEEEKAK 1023
Query: 223 RMQVLKRQVQSLMVHQRKLEAELLQIEERHQEK---KRKFLESTDSFNNELKRLCGLKVE 279
+ LK + +S++ +LE L + E+ QE KRK F+ ++ L E
Sbjct: 1024 NLTKLKNKHESMI---SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
Query: 280 VDM------EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAA-NKGEEK 332
+ M E++ A +A+ +++ ++ +K + S + E+AA NK E++
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 333 KDDENIPMETEETHLEETTESQQNGEE 359
K D +E +T LE+T +S +E
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQE 1167
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/265 (23%), Positives = 112/265 (42%), Gaps = 40/265 (15%)
Query: 108 TDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKG 167
T +E ++ EA+ ++ E + A + A + + AE S + + EK
Sbjct: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQ-ADLEKEELAEELASSLSGRNALQDEKR 1732
Query: 168 EPYMSIQPAEDPDDYDDGF--SMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQ 225
I E+ + + G +M Q+ +L +E+ +E +AR Q
Sbjct: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE---SARQQ 1789
Query: 226 VLKRQVQSLM--VHQRK-------------LEAELLQIEERHQEKKRKFLESTDSFNNEL 270
L+RQ + L +H+ + LEA++ Q+EE+ +++ R+ +T S +
Sbjct: 1790 -LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1848
Query: 271 KRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGE 330
K+L + ++V+ E+ AE Q +EQA K R K+ Q E ++ EE Q N
Sbjct: 1849 KKLKEILLQVEDERKMAE--QYKEQAEK-GNARVKQLKRQLEEAE-----EESQRINANR 1900
Query: 331 EKKDDENIPMETEETHLEETTESQQ 355
K E L+E TES +
Sbjct: 1901 RKLQRE----------LDEATESNE 1915
Score = 40.4 bits (93), Expect = 0.003
Identities = 42/198 (21%), Positives = 84/198 (42%), Gaps = 19/198 (9%)
Query: 197 QRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKK 256
+R R ++ + + D++ + A + R+ + RKL+A++ + ++ +
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE--EAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 257 RKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQS 316
E + K+ L E D+ ++ ++A AE +ARK+ + ++E AE+ S S
Sbjct: 1666 ASRDEIFATAKENEKKAKSL--EADLMQLQEDLAAAE-RARKQADLEKEELAEELASSLS 1722
Query: 317 SIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDS 376
G DE +E LEE E +Q E S K + Q +
Sbjct: 1723 ------------GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ--AEQ 1768
Query: 377 MAEEGTSDSNTGSESNSA 394
++ E ++ +T ++ SA
Sbjct: 1769 LSNELATERSTAQKNESA 1786
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/138 (24%), Positives = 67/138 (48%), Gaps = 18/138 (13%)
Query: 224 MQVLKRQVQSLMVHQRKLEAELLQIEERHQE--KKRKFLESTDSFNNEL--------KRL 273
MQ + ++Q Q+K E EL ++E++H + +++ L+ EL RL
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 274 CGLKVEVD--MEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEE 331
K E++ + ++ A + + E++ ++ Q ER+K A + + + EEE+AA +
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL---EEEEAA---RQ 967
Query: 332 KKDDENIPMETEETHLEE 349
K E + E + LE+
Sbjct: 968 KLQLEKVTAEAKIKKLED 985
Score = 33.5 bits (75), Expect = 0.36
Identities = 49/259 (18%), Positives = 108/259 (41%), Gaps = 25/259 (9%)
Query: 110 EEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEP 169
++ QE L E +K+ + ++ ++ + L+EE +Q+ +E+
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEE---------RNSLQDQLDEEMEAKQN-LERHIS 1367
Query: 170 YMSIQPAEDP---DDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQV 226
++IQ ++ D+ RFQ+ +++ E + T R+Q
Sbjct: 1368 TLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ- 1426
Query: 227 LKRQVQSLMV---HQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEV-DM 282
+++ L+V +QR+L + L + + + + + + + +E R + E +
Sbjct: 1427 --QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA---EAEAREK 1481
Query: 283 EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMET 342
E A +A+A E+A + +EE E+ + + +++ N E +K + +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 343 EE--THLEETTESQQNGEE 359
EE T LEE + Q E+
Sbjct: 1542 EEMKTQLEELEDELQATED 1560
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 55.1 bits (131), Expect = 1e-07
Identities = 39/154 (25%), Positives = 77/154 (50%), Gaps = 6/154 (3%)
Query: 230 QVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEI 289
QV+ R+ E ++ + E + +E++ + E + +++ + E M+K ++
Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMG--EQEEQMQKQEEQM 222
Query: 290 AQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHL-- 347
+ EEQ R +QEE+ E EQ ++ + + +EEQ + E+ ++ E E EE L
Sbjct: 223 GEQEEQMR-KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ 281
Query: 348 -EETTESQQNGEEGTSTPEDKESGQEGVDSMAEE 380
E+T + +Q GE+ E +E +E + M E+
Sbjct: 282 KEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Score = 45.8 bits (107), Expect = 7e-05
Identities = 45/247 (18%), Positives = 103/247 (41%), Gaps = 25/247 (10%)
Query: 111 EKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPY 170
E++E + + E + E E M+ + + EE+ ++++ +M K E
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQ------MGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 171 MSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQ 230
M Q + + + K Q + E + E +M+ + Q
Sbjct: 264 MREQEEQMREQEEQMLKQKEQTEQEEQTGEQ--EEQMREQ----------EEQMREQEEQ 311
Query: 231 VQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIA 290
++ R+ E ++ + EE+ E+K + E + + +++ + E M+K ++
Sbjct: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG--EQEEQMQKQEEQVR 369
Query: 291 QAEEQARKRQEEREKEAAEQAER-----SQSSIVPEEEQAANKGEEKKDDENIPMETEET 345
+ EEQ RK++E+ K+ + ++ Q + E+++ + EE+ ++ M +E
Sbjct: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Query: 346 HLEETTE 352
H+ E E
Sbjct: 430 HMGEQKE 436
Score = 45.1 bits (105), Expect = 1e-04
Identities = 48/253 (18%), Positives = 103/253 (40%), Gaps = 16/253 (6%)
Query: 111 EKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPY 170
E++ + E E + E E M + + E E+E + R+ + GE
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQ--------MQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 171 MSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEIL----SESVVPDVRSVVTTARMQV 226
+Q E+ + K R Q E E + ++ +M+
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 227 LKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIA 286
+ Q++ R+ E ++ + EE+ +++ + E + + +++ K E M +
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMW--KQEEQMGEQE 358
Query: 287 AEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETH 346
++ + EEQ R +QEE+ ++ EQ + + + +EEQ + +E+ ++ M +E
Sbjct: 359 EQMQKQEEQVR-KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ-KEQMGEQKEQMREQEEQ 416
Query: 347 LEETTESQQNGEE 359
+ E E + EE
Sbjct: 417 MGEQKEQMRKQEE 429
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 12/150 (8%)
Query: 223 RMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDM 282
++Q + QVQ RK E ++ + EE+ +E++ + L+ + E + G + E
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ--TEQEEQTGEQEE--- 296
Query: 283 EKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMET 342
++ + EEQ R+ QEE+ +E EQ + + +EEQ + E+ + + M
Sbjct: 297 -----QMREQEEQMRE-QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE-QMWK 349
Query: 343 EETHLEETTESQQNGEEGTSTPEDKESGQE 372
+E + E E Q EE E++ QE
Sbjct: 350 QEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Score = 38.5 bits (88), Expect = 0.011
Identities = 31/173 (17%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 239 RKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARK 298
+K E ++ + EE+ ++++ + E + + ++ V+ E++ + Q EQ +
Sbjct: 216 QKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQ-----VQKQEEQMRKQEEQMREQEEQ 270
Query: 299 RQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGE 358
+E+ E+ ++ + Q E+E+ + EE+ ++ M +E + E + +Q G+
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE--QEEQMGK 328
Query: 359 EGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
+ E KE E + M ++ + G + +E E +K+
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQ---EEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
Score = 35.8 bits (81), Expect = 0.073
Identities = 24/119 (20%), Positives = 46/119 (38%)
Query: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352
E++ + R++E + E R Q + E+E + EE+ ++ M+ +E + E E
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 353 SQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
+ EE E++ QE EE + E + + E+ E
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
Score = 35.4 bits (80), Expect = 0.095
Identities = 21/106 (19%), Positives = 44/106 (41%)
Query: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352
+E QEE+ E EQ ++ + + +EEQ + E+ + E + EE ++ +
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Query: 353 SQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEE 398
++ E+ E +E + E+ + TG + +E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
>gi|169168462 PREDICTED: similar to high mobility group box 3 [Homo
sapiens]
Length = 204
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P +P + +S ++ ++K++NP + + ++ K +G MW +L D EKQ Y+ +
Sbjct: 83 KDPSAPKRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTA 142
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAAL------EEESRQRQSRMEKGEPYMS 172
K +Y + + +S + + +K A+ A +E+ + + RM K Y+S
Sbjct: 143 KLKEKYEKDVA---DSKSKGKFDGSKRPAKVAWKKVEEEDEDEEEMRRRMNKQSVYLS 197
Score = 30.0 bits (66), Expect = 4.0
Identities = 15/69 (21%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 63 PKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAE 122
PK P + Y+ + + ++ K NP + E K W+ ++ +EK ++ + +
Sbjct: 6 PKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMAKTD 64
Query: 123 KIEYNESMK 131
K+ + MK
Sbjct: 65 KVHCDREMK 73
>gi|169168166 PREDICTED: similar to high mobility group box 3 [Homo
sapiens]
Length = 204
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P +P + +S ++ ++K++NP + + ++ K +G MW +L D EKQ Y+ +
Sbjct: 83 KDPSAPKRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTA 142
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAAL------EEESRQRQSRMEKGEPYMS 172
K +Y + + +S + + +K A+ A +E+ + + RM K Y+S
Sbjct: 143 KLKEKYEKDVA---DSKSKGKFDGSKRPAKVAWKKVEEEDEDEEEMRRRMNKQSVYLS 197
Score = 30.0 bits (66), Expect = 4.0
Identities = 15/69 (21%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 63 PKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAE 122
PK P + Y+ + + ++ K NP + E K W+ ++ +EK ++ + +
Sbjct: 6 PKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMAKTD 64
Query: 123 KIEYNESMK 131
K+ + MK
Sbjct: 65 KVHCDREMK 73
>gi|239742753 PREDICTED: similar to high mobility group box 3
isoform 2 [Homo sapiens]
Length = 183
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P +P + +S ++ ++K++NP + + ++ K +G MW +L D EKQ Y+ +
Sbjct: 65 KDPSAPKRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTA 124
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAAL------EEESRQRQSRMEKGEPYMS 172
K +Y + + +S + + +K A+ A +E+ + + RM K Y+S
Sbjct: 125 KLKEKYEKDVA---DSKSKGKFDGSKRPAKVAWKKVEEEDEDEEEMRRRMNKQSVYLS 179
>gi|113416897 PREDICTED: similar to high mobility group box 3
isoform 1 [Homo sapiens]
Length = 201
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P +P + +S ++ ++K++NP + + ++ K +G MW +L D EKQ Y+ +
Sbjct: 83 KDPSAPKRPPSGFFLFSSEIRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKTA 142
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAAL------EEESRQRQSRMEKGEPYMS 172
K +Y + + +S + + +K A+ A +E+ + + RM K Y+S
Sbjct: 143 KLKEKYEKDVA---DSKSKGKFDGSKRPAKVAWKKVEEEDEDEEEMRRRMNKQSVYLS 197
Score = 30.0 bits (66), Expect = 4.0
Identities = 15/69 (21%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 63 PKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAE 122
PK P + Y+ + + ++ K NP + E K W+ ++ +EK ++ + +
Sbjct: 6 PKKPKGKMSAYVFFVQTCREECKKKNP-VNFAEFSKKCSERWKTMSGKEKSKFDEMAKTD 64
Query: 123 KIEYNESMK 131
K+ + MK
Sbjct: 65 KVHCDREMK 73
>gi|71143137 high-mobility group box 3 [Homo sapiens]
Length = 200
Score = 54.7 bits (130), Expect = 2e-07
Identities = 26/108 (24%), Positives = 51/108 (47%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P +P + + + ++K++NP + + ++ K +G MW +L D EKQ Y+ +
Sbjct: 88 KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYITKAA 147
Query: 121 AEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGE 168
K +Y + + Y + + A +EEE + + E+ E
Sbjct: 148 KLKEKYEKDVADYKSKGKFDGAKGPAKVARKKVEEEDEEEEEEEEEEE 195
Score = 35.8 bits (81), Expect = 0.073
Identities = 18/73 (24%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 63 PKPPDKPLMPYMRYSRKVWDQVKASNPDLKL--WEIGKIIGGMWRDLTDEEKQEYLNEYE 120
PK P + Y + + ++ K NP++ + E K W+ ++ +EK ++ +
Sbjct: 6 PKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAK 65
Query: 121 AEKIEYNESMKAY 133
A+K+ Y+ MK Y
Sbjct: 66 ADKVRYDREMKDY 78
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 24/179 (13%)
Query: 233 SLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQA 292
S + + K+EA L+++ + E+ +E T KVE + ++ +
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEE---IIEET-------------KVEDEKSEMEEALTAI 100
Query: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352
E+ +E +KEAAE+ E + EEE AA K K + E E EE E
Sbjct: 101 TEELAVSMKEEKKEAAEEKEEEPEA--EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE 158
Query: 353 SQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
++ +EG + + +E G E +EG+S+ G + T E + E+K+
Sbjct: 159 EEEEEDEGAKSDQAEEGGSE------KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKK 211
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/218 (22%), Positives = 93/218 (42%), Gaps = 10/218 (4%)
Query: 200 HRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKF 259
H+ + EI+ E+ V D +S + A + + S+ +++ E + E +E+
Sbjct: 74 HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAK 133
Query: 260 LESTDSFNNELKRLCGLKVEVD------MEKIAAEIAQAEEQARKRQEEREKEAAEQAER 313
+ E+K G K E + E A+ QAEE +++ EKE EQ E
Sbjct: 134 KSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ-EE 192
Query: 314 SQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEG 373
++ E E+A K E+K ++++ + T+E E +++ E +P K +E
Sbjct: 193 GETEAEAEGEEAEAKEEKKVEEKSEEVATKE---ELVADAKVEKPEKAKSPVPKSPVEEK 249
Query: 374 VDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
S + + S + VEE P+P+ +E
Sbjct: 250 GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE 287
Score = 44.7 bits (104), Expect = 2e-04
Identities = 47/210 (22%), Positives = 90/210 (42%), Gaps = 18/210 (8%)
Query: 218 VVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNEL------- 270
+ ++++Q K + L V Q K E+++ E + +++K + E+ + EL
Sbjct: 54 ITISSKIQKPKVEAPKLKV-QHKFVEEIIE-ETKVEDEKSEMEEALTAITEELAVSMKEE 111
Query: 271 KRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAA--NK 328
K+ + E + E E+A + + E ++E E+ E EE++ A ++
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171
Query: 329 GEEKKDDENIPMETEETHLEE-TTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNT 387
EE ++ E EE EE TE++ GEE + E K + + EE +D+
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231
Query: 388 GSESNS------ATVEEPPTDPIPEDEKKE 411
+ + VEE P+P+ +E
Sbjct: 232 EKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 261
Score = 43.1 bits (100), Expect = 5e-04
Identities = 86/386 (22%), Positives = 149/386 (38%), Gaps = 53/386 (13%)
Query: 51 VTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDE 110
+T SS I PK P L ++ ++ ++ K + ++ E I E
Sbjct: 54 ITISSKIQKPKVEAPK---LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKE 110
Query: 111 EKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPY 170
EK+E E E E E E A SP K EEE ++ + ++G
Sbjct: 111 EKKEAAEEKEEEP-EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA-- 167
Query: 171 MSIQPAEDPDDYDDGFSMKHT----------------ATARFQRNHRLISEILS--ESVV 212
AE+ +G S K A A+ ++ SE ++ E +V
Sbjct: 168 -KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 226
Query: 213 PDVR-SVVTTARMQVLKRQVQ---------SLMVHQRKLEAELLQIEERHQ--------E 254
D + A+ V K V+ S + + K +EE+ + E
Sbjct: 227 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 255 KKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERS 314
+K K S + K K V+ K AE+ + E++ + +E +E E+ E+
Sbjct: 287 EKGKSPVSKSPVEEKAKSPVP-KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 345
Query: 315 QSSI--VPEEEQAANKGEEKKDDENIPM-ETEETHLEETTESQQNGEEGTSTPEDKESGQ 371
+ VPE+++A + +E+ E + + ++ + HLE+ T+ EEG ++KE +
Sbjct: 346 EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK-----EEGKPLQQEKEKEK 400
Query: 372 EGVDSMAEEGTSDSNT-GSESNSATV 396
G + +EE SD GS V
Sbjct: 401 AGGEGGSEEEGSDKGAKGSRKEDIAV 426
Score = 34.7 bits (78), Expect = 0.16
Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 16/104 (15%)
Query: 278 VEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDEN 337
V+V +EK + +E+ + Q+E+EKE A S EE+ ++KG + E+
Sbjct: 377 VKVHLEK------ETKEEGKPLQQEKEKEKAGGEGGS-------EEEGSDKGAKGSRKED 423
Query: 338 IPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVD-SMAEE 380
I + E EE Q+ E+G+ E+K G+D S A+E
Sbjct: 424 IAVNGEVEGKEEV--EQETKEKGSGREEEKGVVTNGLDLSPADE 465
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 53.5 bits (127), Expect = 3e-07
Identities = 71/326 (21%), Positives = 128/326 (39%), Gaps = 60/326 (18%)
Query: 107 LTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEK 166
+ D E++ L + E++ AY N EAA E R RQ R+ +
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQR--------NDDDEEEAARERRRRARQERLRQ 52
Query: 167 GEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQV 226
+ S+ D E+ +++ VPD + TT QV
Sbjct: 53 KQEEESLGQVTDQ------------------------VEVNAQNSVPDEEAKTTTTNTQV 88
Query: 227 LKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIA 286
+ + L + EER Q++ ++ LE F+ + M+
Sbjct: 89 EGDDEAAFL-------ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 141
Query: 287 AE--IAQAEEQARKRQEEREKEAAEQAERS-QSSIVPEEEQAANKGEEKKDDE------- 336
AE + EE++ RQE E E E +S Q + + E+ + +EK+++E
Sbjct: 142 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 337 NIPMETEETHLEE-TTESQQ--------NGEEGTSTPEDKESGQEGVDSMA--EEGTSDS 385
+I E +EE TTESQ+ NG+ + P+ +E ++G D ++ E+ +
Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 386 NTGSESNSATVEEPPTDPIPEDEKKE 411
+E+ A +E + I ++ K+
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKK 287
Score = 50.8 bits (120), Expect = 2e-06
Identities = 62/269 (23%), Positives = 112/269 (41%), Gaps = 33/269 (12%)
Query: 108 TDEEKQEYLNEYEAEKIEYNESM-KAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEK 166
T E++++ + E +IE E++ K+Y + A N K E EEE ++ R
Sbjct: 146 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK--EEEEEEKPKRGSI 203
Query: 167 GEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQV 226
GE + + E + S + T +N ++ SE + +
Sbjct: 204 GENQVEVMVEEKTTE-----SQEETVVMSL-KNGQISSE---------------EPKQEE 242
Query: 227 LKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNEL-KRLCGLKVEVDMEKI 285
+ Q + H K+E E E E+ R E + E K++ + ++ E+
Sbjct: 243 EREQGSDEISHHEKMEEE--DKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK 300
Query: 286 AA--EIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETE 343
AA E + E + R+R E EK AAE+ +R I EE++AA + + K++E E
Sbjct: 301 AAAQERERREAEERERMREEEKRAAEERQR----IKEEEKRAAEERQRIKEEEKRAAEER 356
Query: 344 ETHLEETTESQQNGEEGTSTPEDKESGQE 372
+ EE + + + + E+K +E
Sbjct: 357 QRIKEEEKRAAEERQRARAEEEEKAKVEE 385
Score = 47.8 bits (112), Expect = 2e-05
Identities = 58/273 (21%), Positives = 114/273 (41%), Gaps = 45/273 (16%)
Query: 104 WRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSR 163
WRD + +K++ E E E+ S+ +++ E +EE++ + Q
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSI--------------GENQVEVMVEEKTTESQEE 222
Query: 164 ME----KGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVV 219
K S +P ++ + + H H + E E + +
Sbjct: 223 TVVMSLKNGQISSEEPKQEEEREQGSDEISH---------HEKMEEEDKERAEAERARLE 273
Query: 220 TTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVE 279
R ++ Q + + + ++EAE + QE++R+ E + E KR
Sbjct: 274 AEERERIKAEQDKKIADERARIEAEE---KAAAQERERREAEERERMREEEKRAAE---- 326
Query: 280 VDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIP 339
+ ++I E +A E+ R+R +E EK AAE+ +R I EE++AA + + + +E
Sbjct: 327 -ERQRIKEEEKRAAEE-RQRIKEEEKRAAEERQR----IKEEEKRAAEERQRARAEEE-- 378
Query: 340 METEETHLEETTESQQNGEEGTSTPEDKESGQE 372
E+ +EE ++Q E+ + E K G++
Sbjct: 379 ---EKAKVEEQKRNKQLEEKKHAMQETKIKGEK 408
Score = 39.3 bits (90), Expect = 0.007
Identities = 64/309 (20%), Positives = 121/309 (39%), Gaps = 38/309 (12%)
Query: 108 TDEEKQEYLNEYEAEKIEYNESMKAY--HNSPAYLAYINAKSRAEAALEEESR--QRQSR 163
++E KQE E +++I ++E M+ + A A + A+ R E++ + ++R
Sbjct: 235 SEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERAR 294
Query: 164 MEKGEPYMSIQ----PAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVV 219
+E E + + AE+ + + R + + +E + R+
Sbjct: 295 IEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354
Query: 220 TTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVE 279
R++ +++ R E E ++EE +K+ K LE E K + G KVE
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEE---QKRNKQLEEKKHAMQETK-IKGEKVE 410
Query: 280 VDME--------------KIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQA 325
+E + A Q EE+ K Q +REK ++ + I +++
Sbjct: 411 QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEI---KDEK 467
Query: 326 ANKGEEKKDDENIPMETEETHLEETTESQQNGE------EGTSTPEDKESGQEGVDSMAE 379
K +E K++ M+ ++ T QNGE + T + G+ VD+
Sbjct: 468 IKKDKEPKEEVKSFMDRKKGF---TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA 524
Query: 380 EGTSDSNTG 388
EG G
Sbjct: 525 EGAPQVEAG 533
Score = 37.4 bits (85), Expect = 0.025
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 11/103 (10%)
Query: 269 ELKRLCGLKVEVDMEKIAAEIAQAE---EQARKRQEEREKEAAEQAERSQSSIVPEEEQA 325
EL+R G + EK+ + +A E+ +K++EER K E+ +R + +E+A
Sbjct: 538 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK------QEEA 591
Query: 326 ANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKE 368
K E+++ + E E E + Q+ E+G S +DK+
Sbjct: 592 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLS--DDKK 632
Score = 34.3 bits (77), Expect = 0.21
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 288 EIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKK-----DDENIPMET 342
E + E+ R+R+ E E E E+ ++ Q E E+ K EE++ +++ E
Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE 590
Query: 343 EETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSD 384
+ L E E ++ EE + E M E+G SD
Sbjct: 591 ADRKLREEEEKRRLKEE---IERRRAEAAEKRQKMPEDGLSD 629
Score = 33.5 bits (75), Expect = 0.36
Identities = 41/176 (23%), Positives = 75/176 (42%), Gaps = 11/176 (6%)
Query: 236 VHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKI--AAEIAQAE 293
+ +R+ E E + E+ Q+++ LE + +R L+ E K A + E
Sbjct: 539 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598
Query: 294 EQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTES 353
E+ R+ +EE E+ AE AE+ Q +PE+ ++KK + + +EE E
Sbjct: 599 EEKRRLKEEIERRRAEAAEKRQK--MPED----GLSDDKKPFKCFTPKGSSLKIEERAEF 652
Query: 354 QQNGEEGTSTPEDKESGQ--EGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPED 407
+ +S + +DS E+ TS + G++S T P+P +
Sbjct: 653 LNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTS-AIEGTKSAKPTKPAASDLPVPAE 707
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 53.5 bits (127), Expect = 3e-07
Identities = 88/453 (19%), Positives = 161/453 (35%), Gaps = 74/453 (16%)
Query: 1 MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSH-----------------LAYNNYRLGG 43
M ++P + PP P MP TPG + P S NN+ GG
Sbjct: 96 MHQQPPHPPPDQP----WMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGG 151
Query: 44 NP-----GTNSRVTASSGITIPKP----------PKPPDKPLMPYMRYSRK--------- 79
P G ++ G P P PP P P R R
Sbjct: 152 PPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRS 211
Query: 80 -VWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPA 138
+ VK P + + + + R+ ++ ++E + E E++E S + A
Sbjct: 212 PIALPVKQEPPQIDAVK-RRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKA 270
Query: 139 YL-------AYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHT 191
+ +S+ ++ EEE + G+ S P + D + +
Sbjct: 271 TEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEK 330
Query: 192 ATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIE-- 249
L++EIL + ++ V A + K + L Q A L +
Sbjct: 331 EYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLA--QSSALASLTGLGGL 388
Query: 250 ------ERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEER 303
+ E+ + ES+D+ + EL+ K E K + ++ +Q E
Sbjct: 389 GGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRK-----EKEQQLLHDKQMEE 443
Query: 304 EKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTST 363
EK+ E+ + + + +E+ + + E ++ D ++ E + T E T+ + E
Sbjct: 444 EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEH---- 499
Query: 364 PEDKESGQEGVDSMAEEGTSDSNTGSESNSATV 396
++KE + G+S SN+ + S S+TV
Sbjct: 500 -KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTV 531
Score = 36.2 bits (82), Expect = 0.056
Identities = 34/180 (18%), Positives = 78/180 (43%), Gaps = 8/180 (4%)
Query: 237 HQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGL-KVEVDMEKIAAEIAQAEEQ 295
++ +E E + +E++R S D N R + ++D ++ + +
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 296 ARKRQEEREKEAAE--QAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTES 353
+++ER+KE + +R + E EQ K ++K+++++ +++ L+ ES
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRES 717
Query: 354 QQNGEEGTSTPED---KESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKK 410
++ S +S Q+ S ++ S ++GS+S+ + E P + KK
Sbjct: 718 ERTFSRSGSISVKIIRHDSRQDSKKSTTKD--SKKHSGSDSSGRSSSESPGSSKEKKAKK 775
Score = 32.0 bits (71), Expect = 1.0
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 28/119 (23%)
Query: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352
E+ R++Q++ EKE EQ +RSQ S ++E+ A + E D +P ++ EE
Sbjct: 241 EKMEREKQKKLEKERMEQ-QRSQLS---KKEKKATEDAEGGDGPRLPQRSKFDSDEE--- 293
Query: 353 SQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
EE T E SG+ + S S +E +DP +E+KE
Sbjct: 294 -----EEDTENVEAASSGKV----------------TRSPSPVPQEEHSDPEMTEEEKE 331
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 53.5 bits (127), Expect = 3e-07
Identities = 88/453 (19%), Positives = 161/453 (35%), Gaps = 74/453 (16%)
Query: 1 MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSH-----------------LAYNNYRLGG 43
M ++P + PP P MP TPG + P S NN+ GG
Sbjct: 96 MHQQPPHPPPDQP----WMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGG 151
Query: 44 NP-----GTNSRVTASSGITIPKP----------PKPPDKPLMPYMRYSRK--------- 79
P G ++ G P P PP P P R R
Sbjct: 152 PPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRS 211
Query: 80 -VWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPA 138
+ VK P + + + + R+ ++ ++E + E E++E S + A
Sbjct: 212 PIALPVKQEPPQIDAVK-RRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKA 270
Query: 139 YL-------AYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHT 191
+ +S+ ++ EEE + G+ S P + D + +
Sbjct: 271 TEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEK 330
Query: 192 ATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIE-- 249
L++EIL + ++ V A + K + L Q A L +
Sbjct: 331 EYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLA--QSSALASLTGLGGL 388
Query: 250 ------ERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEER 303
+ E+ + ES+D+ + EL+ K E K + ++ +Q E
Sbjct: 389 GGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRK-----EKEQQLLHDKQMEE 443
Query: 304 EKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTST 363
EK+ E+ + + + +E+ + + E ++ D ++ E + T E T+ + E
Sbjct: 444 EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEH---- 499
Query: 364 PEDKESGQEGVDSMAEEGTSDSNTGSESNSATV 396
++KE + G+S SN+ + S S+TV
Sbjct: 500 -KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTV 531
Score = 36.2 bits (82), Expect = 0.056
Identities = 34/180 (18%), Positives = 78/180 (43%), Gaps = 8/180 (4%)
Query: 237 HQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGL-KVEVDMEKIAAEIAQAEEQ 295
++ +E E + +E++R S D N R + ++D ++ + +
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 296 ARKRQEEREKEAAE--QAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTES 353
+++ER+KE + +R + E EQ K ++K+++++ +++ L+ ES
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRES 717
Query: 354 QQNGEEGTSTPED---KESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKK 410
++ S +S Q+ S ++ S ++GS+S+ + E P + KK
Sbjct: 718 ERTFSRSGSISVKIIRHDSRQDSKKSTTKD--SKKHSGSDSSGRSSSESPGSSKEKKAKK 775
Score = 32.0 bits (71), Expect = 1.0
Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 28/119 (23%)
Query: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352
E+ R++Q++ EKE EQ +RSQ S ++E+ A + E D +P ++ EE
Sbjct: 241 EKMEREKQKKLEKERMEQ-QRSQLS---KKEKKATEDAEGGDGPRLPQRSKFDSDEE--- 293
Query: 353 SQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE 411
EE T E SG+ + S S +E +DP +E+KE
Sbjct: 294 -----EEDTENVEAASSGKV----------------TRSPSPVPQEEHSDPEMTEEEKE 331
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 53.1 bits (126), Expect = 4e-07
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 3/128 (2%)
Query: 61 KPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYE 120
K P P +P + Y + ++K P L ++ K +G MW + ++KQ Y
Sbjct: 226 KDPNAPKRPPSAFFLYFSEYGPKIKGERPGLSFGDVAKKLGEMWNNTAADDKQPYEKRSA 285
Query: 121 AEKIEYNESMKAYHNSPAYLAYINA---KSRAEAALEEESRQRQSRMEKGEPYMSIQPAE 177
K +Y + + AY + A N ++++ EEE + E+ E + E
Sbjct: 286 KLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEEDEDEE 345
Query: 178 DPDDYDDG 185
D +D +DG
Sbjct: 346 DDEDEEDG 353
Score = 32.0 bits (71), Expect = 1.0
Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Query: 293 EEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTE 352
E+++ K +E+ EK+ A + + A K ++KK++E E EE +E E
Sbjct: 281 EKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEE----ENEEDEEDEEEE 336
Query: 353 SQQNGEEGTSTPEDKESGQEGVDSMA 378
+ E+ ED E ++G D +
Sbjct: 337 KDEEDED----EEDDEDEEDGDDEQS 358
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.123 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,890,042
Number of Sequences: 37866
Number of extensions: 936927
Number of successful extensions: 17347
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 557
Number of HSP's successfully gapped in prelim test: 1140
Number of HSP's that attempted gapping in prelim test: 7288
Number of HSP's gapped (non-prelim): 6150
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.