Guide to the Human Genome
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Search of human proteins with 209693426

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
sapiens]
         (437 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   919   0.0  
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   903   0.0  
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    903   0.0  
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   825   0.0  
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   700   0.0  
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...   619   e-177
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]        560   e-159
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]        560   e-159
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]        560   e-159
gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              554   e-158
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]             552   e-157
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]              552   e-157
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]            542   e-154
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...   449   e-126
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]   168   8e-42
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]             142   8e-34
gi|5174517 SMAD family member 7 [Homo sapiens]                        132   6e-31
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            105   1e-22
gi|11276067 snail 2 [Homo sapiens]                                     35   0.13 
gi|146134388 YLP motif containing 1 [Homo sapiens]                     35   0.18 
gi|113865921 hypothetical protein LOC441457 [Homo sapiens]             34   0.23 
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          33   0.39 
gi|19923345 RNA binding motif protein 12 [Homo sapiens]                33   0.39 
gi|23510462 RNA binding motif protein 12 [Homo sapiens]                33   0.39 
gi|46094081 development and differentiation enhancing factor 1 [...    33   0.51 
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    33   0.67 
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     32   0.87 
gi|71274109 nuclear factor of kappa light polypeptide gene enhan...    32   1.1  
gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]                 32   1.1  
gi|70980547 FYVE-finger-containing Rab5 effector protein rabenos...    32   1.5  

>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  919 bits (2374), Expect = 0.0
 Identities = 437/437 (100%), Positives = 437/437 (100%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
           MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60

Query: 61  LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 120
           LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE
Sbjct: 61  LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 120

Query: 121 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI 180
           YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI
Sbjct: 121 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI 180

Query: 181 EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE 240
           EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE
Sbjct: 181 EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE 240

Query: 241 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 300
           PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR
Sbjct: 241 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 300

Query: 301 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 360
           HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF
Sbjct: 301 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 360

Query: 361 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 420
           AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
Sbjct: 361 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 420

Query: 421 KVLTQMGSPSVRCSSMS 437
           KVLTQMGSPSVRCSSMS
Sbjct: 421 KVLTQMGSPSVRCSSMS 437


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  903 bits (2333), Expect = 0.0
 Identities = 437/467 (93%), Positives = 437/467 (93%), Gaps = 30/467 (6%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
           MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60

Query: 61  LEKAITTQNCNTKCVTIP------------------------------RSLDGRLQVSHR 90
           LEKAITTQNCNTKCVTIP                              RSLDGRLQVSHR
Sbjct: 61  LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120

Query: 91  KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 150
           KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV
Sbjct: 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180

Query: 151 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 210
           PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS
Sbjct: 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240

Query: 211 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 270
           MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD
Sbjct: 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300

Query: 271 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 330
           GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct: 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360

Query: 331 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 390
           NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct: 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420

Query: 391 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS
Sbjct: 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  903 bits (2333), Expect = 0.0
 Identities = 437/467 (93%), Positives = 437/467 (93%), Gaps = 30/467 (6%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
           MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60

Query: 61  LEKAITTQNCNTKCVTIP------------------------------RSLDGRLQVSHR 90
           LEKAITTQNCNTKCVTIP                              RSLDGRLQVSHR
Sbjct: 61  LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120

Query: 91  KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 150
           KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV
Sbjct: 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180

Query: 151 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 210
           PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS
Sbjct: 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240

Query: 211 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 270
           MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD
Sbjct: 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300

Query: 271 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 330
           GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct: 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360

Query: 331 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 390
           NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct: 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420

Query: 391 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS
Sbjct: 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  825 bits (2130), Expect = 0.0
 Identities = 392/437 (89%), Positives = 411/437 (94%), Gaps = 12/437 (2%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
           MSSILPFTPP+VKRLLGWKK          GEQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct: 1   MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50

Query: 61  LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 120
           LEKAITTQN NTKC+TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE
Sbjct: 51  LEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE 110

Query: 121 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI 180
           +AFN+KKDEVCVNPYHYQRVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTNFPAGI
Sbjct: 111 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI 170

Query: 181 EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE 240
           EPQSN IPETPPPGY+SEDGETSD Q+N SMD GSP  LSP  +SP +++LDLQPVTY E
Sbjct: 171 EPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCE 228

Query: 241 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 300
           PAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRR
Sbjct: 229 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 288

Query: 301 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 360
           HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF
Sbjct: 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348

Query: 361 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 420
           AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
Sbjct: 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408

Query: 421 KVLTQMGSPSVRCSSMS 437
           KVLTQMGSPS+RCSS+S
Sbjct: 409 KVLTQMGSPSIRCSSVS 425


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  700 bits (1806), Expect = 0.0
 Identities = 328/359 (91%), Positives = 344/359 (95%), Gaps = 2/359 (0%)

Query: 79  RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQ 138
           RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQ
Sbjct: 25  RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84

Query: 139 RVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISE 198
           RVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SE
Sbjct: 85  RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSE 143

Query: 199 DGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGE 258
           DGETSD Q+N SMD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGE
Sbjct: 144 DGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGE 202

Query: 259 TFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 318
           TFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAE
Sbjct: 203 TFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAE 262

Query: 319 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 378
           CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL
Sbjct: 263 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 322

Query: 379 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 323 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score =  619 bits (1596), Expect = e-177
 Identities = 292/322 (90%), Positives = 307/322 (95%), Gaps = 2/322 (0%)

Query: 116 IENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTN 175
           +E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTN
Sbjct: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60

Query: 176 FPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQP 235
           FPAGIEPQSN IPETPPPGY+SEDGETSD Q+N SMD GSP  LSP  +SP +++LDLQP
Sbjct: 61  FPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQP 118

Query: 236 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 295
           VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct: 119 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 178

Query: 296 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 355
           E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct: 179 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 238

Query: 356 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 415
           NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct: 239 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298

Query: 416 LQWLDKVLTQMGSPSVRCSSMS 437
           LQWLDKVLTQMGSPS+RCSS+S
Sbjct: 299 LQWLDKVLTQMGSPSIRCSSVS 320


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  560 bits (1442), Expect = e-159
 Identities = 287/479 (59%), Positives = 337/479 (70%), Gaps = 59/479 (12%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           M+S+  FT P VKRLLGWK             Q  +EEKW EKAV +LVKKLKK  G ++
Sbjct: 4   MASLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 50

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELEKA+++    +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK ++ C
Sbjct: 51  ELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------ILTELPPLDDYTHSIPEN 173
           E+ F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH E      +L +   L      +P+N
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQN 170

Query: 174 TNFPAG----------IEPQSNYIP------------------------ETPPPGYISED 199
             FP            + P S Y P                        +TPPP Y+  D
Sbjct: 171 ATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPD 230

Query: 200 GETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGET 259
            +   Q  +Q MDT +   + P  +  ++ S D+QPV Y EP  WCSI YYELN RVGE 
Sbjct: 231 DQMG-QDNSQPMDTSN--NMIPQIMPSIS-SRDVQPVAYEEPKHWCSIVYYELNNRVGEA 286

Query: 260 FHASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 318
           FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AE
Sbjct: 287 FHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAE 346

Query: 319 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 378
           CLSDS+IFVQS NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+L
Sbjct: 347 CLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYEL 406

Query: 379 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           T+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 407 TKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  560 bits (1442), Expect = e-159
 Identities = 287/479 (59%), Positives = 337/479 (70%), Gaps = 59/479 (12%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           M+S+  FT P VKRLLGWK             Q  +EEKW EKAV +LVKKLKK  G ++
Sbjct: 4   MASLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 50

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELEKA+++    +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK ++ C
Sbjct: 51  ELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------ILTELPPLDDYTHSIPEN 173
           E+ F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH E      +L +   L      +P+N
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQN 170

Query: 174 TNFPAG----------IEPQSNYIP------------------------ETPPPGYISED 199
             FP            + P S Y P                        +TPPP Y+  D
Sbjct: 171 ATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPD 230

Query: 200 GETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGET 259
            +   Q  +Q MDT +   + P  +  ++ S D+QPV Y EP  WCSI YYELN RVGE 
Sbjct: 231 DQMG-QDNSQPMDTSN--NMIPQIMPSIS-SRDVQPVAYEEPKHWCSIVYYELNNRVGEA 286

Query: 260 FHASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 318
           FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AE
Sbjct: 287 FHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAE 346

Query: 319 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 378
           CLSDS+IFVQS NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+L
Sbjct: 347 CLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYEL 406

Query: 379 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           T+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 407 TKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  560 bits (1442), Expect = e-159
 Identities = 287/479 (59%), Positives = 337/479 (70%), Gaps = 59/479 (12%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           M+S+  FT P VKRLLGWK             Q  +EEKW EKAV +LVKKLKK  G ++
Sbjct: 4   MASLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 50

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELEKA+++    +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK ++ C
Sbjct: 51  ELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------ILTELPPLDDYTHSIPEN 173
           E+ F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH E      +L +   L      +P+N
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQN 170

Query: 174 TNFPAG----------IEPQSNYIP------------------------ETPPPGYISED 199
             FP            + P S Y P                        +TPPP Y+  D
Sbjct: 171 ATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPD 230

Query: 200 GETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGET 259
            +   Q  +Q MDT +   + P  +  ++ S D+QPV Y EP  WCSI YYELN RVGE 
Sbjct: 231 DQMG-QDNSQPMDTSN--NMIPQIMPSIS-SRDVQPVAYEEPKHWCSIVYYELNNRVGEA 286

Query: 260 FHASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 318
           FHAS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AE
Sbjct: 287 FHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAE 346

Query: 319 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 378
           CLSDS+IFVQS NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+L
Sbjct: 347 CLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYEL 406

Query: 379 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           T+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 407 TKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  554 bits (1427), Expect = e-158
 Identities = 281/447 (62%), Positives = 330/447 (73%), Gaps = 33/447 (7%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           +SS+  FT P VKRLLGWK             Q  +EEKW EKAV SLVKKLKK  G +D
Sbjct: 7   ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELE+A++     +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 54  ELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYT----HS---IPE 172
           E+ F  K+ EVC+NPYHY+RVETPVLPPVLVPRH+E   +L  L  +     HS   +P 
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPH 173

Query: 173 NTNFPAGIE-PQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSL 231
           N  +P   + P  + +P +P   +       S    +     GSP+E      SP  HS 
Sbjct: 174 NATYPDSFQQPPCSALPPSPSHAF-----SQSPCTASYPHSPGSPSEPE----SPYQHS- 223

Query: 232 DLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGLLSNVN 290
           D +PV Y EP  WCS+AYYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLSNVN
Sbjct: 224 DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVN 283

Query: 291 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 350
           RN+T+E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC
Sbjct: 284 RNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGC 343

Query: 351 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 410
           +LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+
Sbjct: 344 SLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 403

Query: 411 HLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 404 HLHGPLQWLDKVLTQMGSPHNPISSVS 430


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  552 bits (1422), Expect = e-157
 Identities = 283/477 (59%), Positives = 332/477 (69%), Gaps = 54/477 (11%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           ++S+  FT P VKRLLGWK             Q  +EEKW EKAV +LVKKLKK  G ++
Sbjct: 3   VTSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 49

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELEKA++     + CVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 50  ELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------ILTELPPLDDYTHSIPEN 173
           E+ F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH+E      +L +   L      +P N
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLN 169

Query: 174 TNFPAGIE-PQSNYIPETPPPGYISEDGETSDQQLNQ--SMDTGSPAEL----------- 219
             FP   + P S+  P +P   Y +  G +S    +   S D GSP ++           
Sbjct: 170 ATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLP 229

Query: 220 ------------------SPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFH 261
                             +P   S +N   D+Q V Y EP  WCSI YYELN RVGE FH
Sbjct: 230 PEDPMTQDGSQPMDTNMMAPPLPSEINRG-DVQAVAYEEPKHWCSIVYYELNNRVGEAFH 288

Query: 262 ASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECL 320
           AS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AECL
Sbjct: 289 ASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECL 348

Query: 321 SDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTR 380
           SDS+IFVQS NCN  +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+
Sbjct: 349 SDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTK 408

Query: 381 MCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 409 MCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  552 bits (1422), Expect = e-157
 Identities = 283/477 (59%), Positives = 332/477 (69%), Gaps = 54/477 (11%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           ++S+  FT P VKRLLGWK             Q  +EEKW EKAV +LVKKLKK  G ++
Sbjct: 3   VTSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKGAME 49

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELEKA++     + CVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 50  ELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTE------ILTELPPLDDYTHSIPEN 173
           E+ F  K+ EVC+NPYHY+RVE+PVLPPVLVPRH+E      +L +   L      +P N
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLN 169

Query: 174 TNFPAGIE-PQSNYIPETPPPGYISEDGETSDQQLNQ--SMDTGSPAEL----------- 219
             FP   + P S+  P +P   Y +  G +S    +   S D GSP ++           
Sbjct: 170 ATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLP 229

Query: 220 ------------------SPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFH 261
                             +P   S +N   D+Q V Y EP  WCSI YYELN RVGE FH
Sbjct: 230 PEDPMTQDGSQPMDTNMMAPPLPSEINRG-DVQAVAYEEPKHWCSIVYYELNNRVGEAFH 288

Query: 262 ASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECL 320
           AS  S+ VDGFTDPSN++ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AECL
Sbjct: 289 ASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECL 348

Query: 321 SDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTR 380
           SDS+IFVQS NCN  +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+
Sbjct: 349 SDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTK 408

Query: 381 MCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 409 MCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score =  542 bits (1397), Expect = e-154
 Identities = 282/474 (59%), Positives = 333/474 (70%), Gaps = 50/474 (10%)

Query: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
           +SS+  FT P VKRLLGWK             Q  +EEKW EKAV SLVKKLKK  G +D
Sbjct: 7   ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53

Query: 60  ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
           ELE+A++     +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 54  ELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113

Query: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYT----HS---IPE 172
           E+ F  K+ EVC+NPYHY+RVETPVLPPVLVPRH+E   +L  L  +     HS   +P 
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPH 173

Query: 173 NTNFPAGIE-PQSNYIPETPP---------------PGYISE---------DGETSDQQL 207
           N  +P   + P  + +P +P                PG  SE         D        
Sbjct: 174 NATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHA 233

Query: 208 NQSMDTGSPAELSPTTLSPVNHSL---DLQPVTYSEPAFWCSIAYYELNQRVGETFHASQ 264
            ++ +T S   +  T    V  S+   D +PV Y EP  WCS+AYYELN RVGETF AS 
Sbjct: 234 TEASETQSGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASS 293

Query: 265 PSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDS 323
            S+ +DGFTDPSN+  RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AEC+SDS
Sbjct: 294 RSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDS 353

Query: 324 AIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT 383
           +IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCT
Sbjct: 354 SIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCT 413

Query: 384 IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           IRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SS+S
Sbjct: 414 IRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score =  449 bits (1156), Expect = e-126
 Identities = 212/231 (91%), Positives = 222/231 (96%), Gaps = 1/231 (0%)

Query: 207 LNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPS 266
           +N SMD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS
Sbjct: 1   MNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPS 59

Query: 267 LTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIF 326
           +TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIF
Sbjct: 60  MTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 119

Query: 327 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 386
           VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM
Sbjct: 120 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 179

Query: 387 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
           SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 180 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score =  168 bits (426), Expect = 8e-42
 Identities = 101/241 (41%), Positives = 135/241 (56%), Gaps = 40/241 (16%)

Query: 226 PVNHSLDLQPVTYSEPA--FWCSIAYYELNQRVGETFH--ASQPSLTVDGFTDPSNSERF 281
           PV++ L  QP   + PA  +WCSIAY+E++ +VGETF   +S P +TVDG+ DPS  +RF
Sbjct: 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362

Query: 282 CLGLLSNVNRNATVEMTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 340
           CLG LSNV+R   +E  R HIG+GV+L   G G+V+  CLSD A+FVQS   ++  G  P
Sbjct: 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422

Query: 341 A-TVCKIPPGCNLKIFN--------NQEFAALLAQSVNQGFE------------------ 373
              V KI P   +K+F+         Q+ A   A +  Q                     
Sbjct: 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482

Query: 374 --------AVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQ 425
                    V  L R+C +RMSFVKGWG +Y RQ++  TPCWIE+HL+  LQ LD+VL  
Sbjct: 483 SLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHT 542

Query: 426 M 426
           M
Sbjct: 543 M 543



 Score =  142 bits (358), Expect = 6e-34
 Identities = 73/138 (52%), Positives = 96/138 (69%), Gaps = 3/138 (2%)

Query: 33  QNGQEEKWCEKAVKSLVKKLK-KTGRLDELEKAITTQNCN-TKCVTIPRSLDGRLQVSHR 90
           Q G+ E + ++A++SLVKKLK K   LD L  AITT   + +KCVTI R+LDGRLQV+ R
Sbjct: 28  QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87

Query: 91  KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 150
           KG PHVIY RLWRWPDLH  +ELK ++ C+YAF+LK D VCVNPYHY+RV +P +    +
Sbjct: 88  KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146

Query: 151 PRHTEILTELPPLDDYTH 168
              +   + +   D+Y H
Sbjct: 147 TLQSNAPSSMMVKDEYVH 164


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score =  142 bits (357), Expect = 8e-34
 Identities = 118/396 (29%), Positives = 178/396 (44%), Gaps = 61/396 (15%)

Query: 28  AGGGEQNGQE------EKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPRS 80
           AGGG            E+  +    SL+K+LK+   LD L +A+ ++      CV +PR+
Sbjct: 153 AGGGRSREARSRLLLLEQELKTVTYSLLKRLKERS-LDTLLEAVESRGGVPGGCVLVPRA 211

Query: 81  LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC-EYAFNLKKDEVCVNPYHYQR 139
               L++  +   P ++  RL+RWPDL    ELK +  C  +A       VC NPYH+ R
Sbjct: 212 ---DLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSR 268

Query: 140 VETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISED 199
           +  P  PP             PP   Y+   P +   P  +   +    ET         
Sbjct: 269 LCGPESPP-------------PP---YSRLSPRDEYKPLDLSDSTLSYTET--------- 303

Query: 200 GETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGET 259
                 +   S+ T +P E S  ++SP            ++P+ WCS+AY+E   RVG  
Sbjct: 304 ------EATNSLIT-APGEFSDASMSP----------DATKPSHWCSVAYWEHRTRVGRL 346

Query: 260 FHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAEC 319
           +     ++++  F D      FCLG L+   R+ +V  TR  IG G+ L      V+A  
Sbjct: 347 YAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYN 404

Query: 320 LSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLT 379
             +  IFV SP  +   G     V K+PPG ++K+F + E + L         +  Y   
Sbjct: 405 RGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVF-DFERSGLQHAPEPDAADGPYDPN 462

Query: 380 RMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 415
              ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 463 ---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495


>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score =  132 bits (332), Expect = 6e-31
 Identities = 117/404 (28%), Positives = 182/404 (45%), Gaps = 70/404 (17%)

Query: 22  AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPRS 80
           A G+G AGG E +       +    S++KKLK+  +L+ L +A+ ++    T C+ +P  
Sbjct: 79  AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131

Query: 81  LDGRL-----------QVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDE 129
           LD RL           Q      LP ++ C+++RWPDL    E+K +  CE    +  + 
Sbjct: 132 LDCRLGPGAPAGAQPAQPPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPEL 190

Query: 130 VCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPE 189
           VC NP+H  R+     PP             PP   Y                       
Sbjct: 191 VCCNPHHLSRLCELESPP-------------PPYSRY----------------------- 214

Query: 190 TPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAY 249
             P  ++    +  D  +  S +TG    L+P  LS  +  L L+P    + + WC +AY
Sbjct: 215 --PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQLLLEP---GDRSHWCVVAY 266

Query: 250 YELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLY 309
           +E   RVG  +   +PSL  D F D      FCLG L++ N++  V+  R  IG G++L 
Sbjct: 267 WEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLT 324

Query: 310 YIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVN 369
                V+    S   IF++S   +         V K+ PG ++K F+ ++  +L  Q  N
Sbjct: 325 REVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPN 381

Query: 370 QGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 413
              E + Q     T+++SFVKGWG  Y RQ ++S PCW+E+  N
Sbjct: 382 D-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 424


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score =  105 bits (261), Expect = 1e-22
 Identities = 72/217 (33%), Positives = 106/217 (48%), Gaps = 20/217 (9%)

Query: 212 DTGSPAELSPTTLS----PVNHSLDLQPVTYSE---------PAFWCSIAYYELNQRVGE 258
           D   P +LS +TLS       +SL   P  +S+         P+ WCS+AY+E   RVG 
Sbjct: 25  DEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGR 84

Query: 259 TFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 318
            +     ++++  F D      FCLG L+   R+ +V  TR  IG G+ L      V+A 
Sbjct: 85  LYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAY 142

Query: 319 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 378
              +  IFV SP  +   G     V K+PPG ++K+F+ +      A   +   +  Y  
Sbjct: 143 NRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAA-DGPYDP 200

Query: 379 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 415
               ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 201 N---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234


>gi|11276067 snail 2 [Homo sapiens]
          Length = 268

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 14/118 (11%)

Query: 130 VCVNPYHYQRVETPVLPPVLVPRHTEILTE--LPPLDDYTHSIPENTNFPAGIEPQSNY- 186
           V ++PY Y+    PV+P        EIL+     P+  +T + P +   P G+ P S Y 
Sbjct: 27  VIISPYLYESYSMPVIP------QPEILSSGAYSPITVWTTAAPFHAQLPNGLSPLSGYS 80

Query: 187 -----IPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYS 239
                +   PP    S+D   S+  ++   +        P  +       +L   TYS
Sbjct: 81  SSLGRVSPPPPSDTSSKDHSGSESPISDEEERLQSKLSDPHAIEAEKFQCNLCNKTYS 138


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 2/99 (2%)

Query: 146 PPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQ 205
           PP LVP   E   E PP+   ++  P  +  P    P S Y P +  P         S  
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194

Query: 206 QLNQS--MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPA 242
             +QS    T S +  S ++ S ++HS    P + + P+
Sbjct: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS 233


>gi|113865921 hypothetical protein LOC441457 [Homo sapiens]
          Length = 492

 Score = 34.3 bits (77), Expect = 0.23
 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 19/154 (12%)

Query: 126 KKDEVCVNPYHYQR-VETPV-LPPVLVPR--HTEILTELPP---------LDDYTHSIPE 172
           K    C+ P   QR  ET   LPP   PR   T++  E+PP         +++   S P 
Sbjct: 337 KAPTACLPPPRPQRPAETKAHLPPPRPPRPAETKVPEEIPPEVVQEYVDIMEELLGSHPG 396

Query: 173 NTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLD 232
           +T  P G   +     E P      EDG TSD  L   +D     E   T +  V H   
Sbjct: 397 DTGEPEGQREKGKV--EQPQ----EEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRF 450

Query: 233 LQPVTYSEPAFWCSIAYYELNQRVGETFHASQPS 266
           L+ +   +P         EL Q  G T     PS
Sbjct: 451 LEELLSPDPQMDFLALSQELEQEEGLTLAQGAPS 484


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 33.5 bits (75), Expect = 0.39
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 6/102 (5%)

Query: 169  SIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVN 228
            S P+  +   G +P    IPE+ PP  I+    T+  +   +  +  P   S T LS  +
Sbjct: 1250 SQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGE--PAASSSRPVAPSGTALSTTS 1307

Query: 229  HSLDLQPVTYSEPAFWCSIAYYELNQ----RVGETFHASQPS 266
              L+  P    E  F  S+A   L      RVG+   +++P+
Sbjct: 1308 SKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT 1349


>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 33.5 bits (75), Expect = 0.39
 Identities = 29/127 (22%), Positives = 50/127 (39%), Gaps = 12/127 (9%)

Query: 143 PVLPPVLVPRHTEILTELPPLDDY--THSIPENTNFPAGIEPQSNYIPETPPPGY---IS 197
           P +PP+ VP     L  +PP+       S+P  T  P    P S   P  PPP       
Sbjct: 203 PSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP----PMSGMPPLNPPPVAPLPAG 258

Query: 198 EDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSI---AYYELNQ 254
            +G  +   LN +++      L+P     +N    ++P+  +    + S+    +  +  
Sbjct: 259 MNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPINPDDLYVSVHGMPFSAMEN 318

Query: 255 RVGETFH 261
            V + FH
Sbjct: 319 DVRDFFH 325


>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 33.5 bits (75), Expect = 0.39
 Identities = 29/127 (22%), Positives = 50/127 (39%), Gaps = 12/127 (9%)

Query: 143 PVLPPVLVPRHTEILTELPPLDDY--THSIPENTNFPAGIEPQSNYIPETPPPGY---IS 197
           P +PP+ VP     L  +PP+       S+P  T  P    P S   P  PPP       
Sbjct: 203 PSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLP----PMSGMPPLNPPPVAPLPAG 258

Query: 198 EDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSI---AYYELNQ 254
            +G  +   LN +++      L+P     +N    ++P+  +    + S+    +  +  
Sbjct: 259 MNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPINPDDLYVSVHGMPFSAMEN 318

Query: 255 RVGETFH 261
            V + FH
Sbjct: 319 DVRDFFH 325


>gi|46094081 development and differentiation enhancing factor 1 [Homo
            sapiens]
          Length = 1129

 Score = 33.1 bits (74), Expect = 0.51
 Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 13/130 (10%)

Query: 124  NLKKDEVCVNPYHYQR----VETPVLPPV--LVPRHTEI-----LTELPPLDDYTHSIPE 172
            +L  D+  + P  +Q+     E P  PP   L P+ TE+     + +LPP        P+
Sbjct: 908  HLSLDKATIPPEIFQKSSQLAELPQKPPPGDLPPKPTELAPKPQIGDLPPKPGELPPKPQ 967

Query: 173  NTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLD 232
              + P   +PQ + +P  P    +    +  D          SP    P+ ++  +H LD
Sbjct: 968  LGDLPP--KPQLSDLPPKPQMKDLPPKPQLGDLLAKSQTGDVSPKAQQPSEVTLKSHPLD 1025

Query: 233  LQPVTYSEPA 242
            L P   S  A
Sbjct: 1026 LSPNVQSRDA 1035


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 32.7 bits (73), Expect = 0.67
 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 17/149 (11%)

Query: 105 PDLHSHHELKAIENCEYAFNLK----KDEVCVNPYHYQRVETPVLPPVLVPRHT-----E 155
           PD+ +HH L      E +F L+    ++   VN  H Q V   ++P  ++   +     E
Sbjct: 33  PDIDNHHALIEYNEAECSFVLQDFNSRNGTFVNECHIQNVAVKLIPGDILRFGSAGLTYE 92

Query: 156 ILTELPPLDDYTHSIPENTNFPAGIEPQSNYIP-ETPPPGYISEDGETSDQQLNQSMDTG 214
           ++ E PP   +   +     +P    P++   P + PPP +I          + +S    
Sbjct: 93  LVIENPPPVSFPW-MRGPAPWPGPQPPRATQQPNQAPPPSHIPFHQGVQPAPMQRSWSQA 151

Query: 215 SPAELSPTTLSPVNHSLDLQPVTYSEPAF 243
            P    PT + P +H    +PV+ ++  F
Sbjct: 152 FP---RPTVVLPASHR---RPVSANKEMF 174


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 32.3 bits (72), Expect = 0.87
 Identities = 58/234 (24%), Positives = 82/234 (35%), Gaps = 28/234 (11%)

Query: 50   KKLKKTGRLDELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPD-LH 108
            K+ +K  +  E+EK   T+N      + P + D  L+     G P V    L   P  L 
Sbjct: 1596 KEKEKDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGPPSVTVVTLESAPSALE 1655

Query: 109  SHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTH 168
                 K +E       L  +E  V P        P   P   P       +LPP  D   
Sbjct: 1656 KTTGDKTVE-----APLVTEEKTVEPATVSEEAKPASEPAPAPVEQLEQVDLPPGAD--- 1707

Query: 169  SIPENTNFPAGIEPQSN-----YIPETPP-PGYISEDGETS-DQQLNQSMDTGSPAELSP 221
               E    PAG+E  S+     Y+   PP PG      E++ D + + +     PA+ S 
Sbjct: 1708 PDKEAAMMPAGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSE 1767

Query: 222  TTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDP 275
                P     D      +EP         + NQ+  E    SQP  + D   DP
Sbjct: 1768 EANEPKAEKPD--ATADAEP---------DANQK-AEAAPESQPPASEDLEVDP 1809


>gi|71274109 nuclear factor of kappa light polypeptide gene enhancer
           in B-cells inhibitor, epsilon [Homo sapiens]
          Length = 500

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 13/80 (16%)

Query: 169 SIPENTNFPAGIEPQSNYIPETPPPGYISE-------DGETSDQQLNQSMDT------GS 215
           S+PE+T+ PA      +  P T PPG + E       DGE +D     S  T      G 
Sbjct: 167 SLPESTSAPASGPSDGSPQPCTHPPGPVKEPQEKEDADGERADSTYGSSSLTYTLSLLGG 226

Query: 216 PAELSPTTLSPVNHSLDLQP 235
           P    P    P+ H   L P
Sbjct: 227 PEAEDPAPRLPLPHVGALSP 246


>gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]
          Length = 863

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 150 VPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQ 209
           VP+  ++  ++P L D  H          G++P    +P+  PP  I +D  + D+ +NQ
Sbjct: 595 VPKKFDVSIDMPDLLDINHLRAR------GLQPGEEELPDISPPIVIPDD--SKDRLMNQ 646

Query: 210 SMDTGSPAELSPTTLSPVNHSLD 232
            +D     E S   L+ +   L+
Sbjct: 647 LIDPSDIDESSVMQLAEMGFPLE 669


>gi|70980547 FYVE-finger-containing Rab5 effector protein
           rabenosyn-5 [Homo sapiens]
          Length = 784

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 188 PETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQP 235
           P++P P   SE+ E   Q+L+  +  G+P E  PT ++P     D  P
Sbjct: 682 PDSPAPNPFSEEDEHPQQRLSSPLVPGNPFE-EPTCINPFEMDSDSGP 728


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,062,403
Number of Sequences: 37866
Number of extensions: 1037549
Number of successful extensions: 4437
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 4327
Number of HSP's gapped (non-prelim): 88
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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