Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 209413752

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209413752 synapsin III isoform IIIa [Homo sapiens]
         (580 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209413752 synapsin III isoform IIIa [Homo sapiens]                1164   0.0  
gi|209413756 synapsin III isoform IIIg [Homo sapiens]                1158   0.0  
gi|209413754 synapsin III isoform IIIc [Homo sapiens]                 886   0.0  
gi|19924103 synapsin II isoform IIa [Homo sapiens]                    652   0.0  
gi|19924099 synapsin I isoform Ia [Homo sapiens]                      611   e-175
gi|19924097 synapsin I isoform Ib [Homo sapiens]                      595   e-170
gi|19924101 synapsin II isoform IIb [Homo sapiens]                    573   e-163
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    62   1e-09
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     59   9e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    59   1e-08
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    58   3e-08
gi|58530845 zyxin [Homo sapiens]                                       57   5e-08
gi|4508047 zyxin [Homo sapiens]                                        57   5e-08
gi|40353727 synaptopodin isoform A [Homo sapiens]                      56   1e-07
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    56   1e-07
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...    55   2e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    55   2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          54   4e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          54   4e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    54   4e-07
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]          53   7e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         53   7e-07
gi|119943102 CREB binding protein isoform b [Homo sapiens]             53   9e-07
gi|119943104 CREB binding protein isoform a [Homo sapiens]             53   9e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   1e-06
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 52   1e-06
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                   52   2e-06
gi|41281612 zinc finger protein 828 [Homo sapiens]                     52   2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   3e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    51   3e-06

>gi|209413752 synapsin III isoform IIIa [Homo sapiens]
          Length = 580

 Score = 1164 bits (3011), Expect = 0.0
 Identities = 580/580 (100%), Positives = 580/580 (100%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF 60
           MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF
Sbjct: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF 60

Query: 61  SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR 120
           SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR
Sbjct: 61  SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR 120

Query: 121 VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL 180
           VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL
Sbjct: 121 VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL 180

Query: 181 VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA 240
           VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA
Sbjct: 181 VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA 240

Query: 241 PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS 300
           PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS
Sbjct: 241 PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS 300

Query: 301 NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR 360
           NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR
Sbjct: 301 NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR 360

Query: 361 DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP 420
           DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP
Sbjct: 361 DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP 420

Query: 421 GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR 480
           GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR
Sbjct: 421 GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR 480

Query: 481 SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 540
           SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ
Sbjct: 481 SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 540

Query: 541 SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD 580
           SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD
Sbjct: 541 SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD 580


>gi|209413756 synapsin III isoform IIIg [Homo sapiens]
          Length = 579

 Score = 1158 bits (2995), Expect = 0.0
 Identities = 579/580 (99%), Positives = 579/580 (99%), Gaps = 1/580 (0%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF 60
           MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF
Sbjct: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF 60

Query: 61  SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR 120
           SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR
Sbjct: 61  SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR 120

Query: 121 VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL 180
           VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVV RSFKPDFILVRQHAYSMALGEDYRSL
Sbjct: 121 VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVV-RSFKPDFILVRQHAYSMALGEDYRSL 179

Query: 181 VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA 240
           VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA
Sbjct: 180 VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA 239

Query: 241 PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS 300
           PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS
Sbjct: 240 PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS 299

Query: 301 NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR 360
           NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR
Sbjct: 300 NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR 359

Query: 361 DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP 420
           DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP
Sbjct: 360 DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP 419

Query: 421 GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR 480
           GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR
Sbjct: 420 GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQR 479

Query: 481 SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 540
           SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ
Sbjct: 480 SPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 539

Query: 541 SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD 580
           SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD
Sbjct: 540 SLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASLFSD 579


>gi|209413754 synapsin III isoform IIIc [Homo sapiens]
          Length = 444

 Score =  886 bits (2290), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF 60
           MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF
Sbjct: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLF 60

Query: 61  SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR 120
           SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR
Sbjct: 61  SSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIR 120

Query: 121 VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL 180
           VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL
Sbjct: 121 VEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSL 180

Query: 181 VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA 240
           VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA
Sbjct: 181 VIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMVTA 240

Query: 241 PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS 300
           PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS
Sbjct: 241 PHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGS 300

Query: 301 NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR 360
           NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR
Sbjct: 301 NYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGR 360

Query: 361 DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP 420
           DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP
Sbjct: 361 DYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP 420

Query: 421 GQAQLGPQLGQPQPRPPPQ 439
           GQAQLGPQLGQPQPRPPPQ
Sbjct: 421 GQAQLGPQLGQPQPRPPPQ 439


>gi|19924103 synapsin II isoform IIa [Homo sapiens]
          Length = 582

 Score =  652 bits (1682), Expect = 0.0
 Identities = 350/605 (57%), Positives = 429/605 (70%), Gaps = 49/605 (8%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD---------------SSTSSP--ASPAMERR 43
           MNFLRRRLSDSSF+ANLPNGYMTDLQRP+               S++++P  ASP  ERR
Sbjct: 2   MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61

Query: 44  HPQ-----PLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVID 98
            P      P  A   S GSS FSSLS A+KQ   A++GL++ P P+    ++ ++LLV+D
Sbjct: 62  PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTA-ASAGLVDAPAPAPAAARKAKVLLVVD 120

Query: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158
           + H DW+K F GKKV G+ +I+VEQAEFSELNL A+  G   VDMQV+RNGTKVV RSF+
Sbjct: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFR 179

Query: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218
           PDF+L+RQHA+ MA  ED+R L+IG+QY GLP++NSL S+YNFC KPWVF+QL+ I+ +L
Sbjct: 180 PDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTL 239

Query: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278
           G EKFPL+EQT++PNHK M+T P FPVVVK+GHAH+GMGK+KVEN  DFQDI SVVA+ +
Sbjct: 240 GGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQ 299

Query: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338
           TYAT E FIDSKYDIR+QKIG+NYKAYMRTSISGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 300 TYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDT 359

Query: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQL-- 396
           CSEMFGGLDICAVKAVH KDG+DYI EVMD SMPLIGEH  EDRQL+ +LV+SKM+QL  
Sbjct: 360 CSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLS 419

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 456
             P  +   PL    PQ  + K P  ++  PQ      RPPPQGGP Q Q  QP     P
Sbjct: 420 RTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQ------RPPPQGGPGQPQGMQPPGKVLP 473

Query: 457 SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQG 516
             +RL P    P S  S S     +P  P     + G +P+ +S       ++ +PP+  
Sbjct: 474 -PRRLPPGPSLPPSSSSSSSSSSSAPQRPG-GPTTHGDAPSSSSS-----LAEAQPPLAA 526

Query: 517 RSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTS-QRGTPSEDEAKAETIRNLRKSFA 575
                Q         PHP LNKSQSLTN+ S S++S  R + +EDEAKAETIR+LRKSFA
Sbjct: 527 PPQKPQ---------PHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRKSFA 577

Query: 576 SLFSD 580
           SLFSD
Sbjct: 578 SLFSD 582


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score =  611 bits (1576), Expect = e-175
 Identities = 358/707 (50%), Positives = 444/707 (62%), Gaps = 129/707 (18%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49
           MN+LRRRLSDS+FMANLPNGYMTDLQRP             +T  P +   ER      A
Sbjct: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60

Query: 50  ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98
           AS ++P      G   FSSLS+A+KQ   A +    E  G  +    R     R+LLVID
Sbjct: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120

Query: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158
           + HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+  GG  VDM+V+RNG KVV RS K
Sbjct: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLK 179

Query: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218
           PDF+L+RQHA+SMA   DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++   L
Sbjct: 180 PDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKL 239

Query: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278
           G E+FPL++QTF+PNHK M+++  +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ K
Sbjct: 240 GTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTK 299

Query: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338
           TYAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 300 TYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDT 359

Query: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQ-LP 397
           CSE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+Q LP
Sbjct: 360 CSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALP 419

Query: 398 M-------PG----GTAPSP-LRPWAPQIKS--AKSPGQAQLGPQLGQPQP--------- 434
                   PG    G  PSP   P   Q     A  P Q +  PQ G PQP         
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479

Query: 435 ----RPPPQG-------GPRQAQSPQPQRSGSPSQQRLSP----------QGQQ------ 467
               RPPPQG       GP  A SP PQR  SP+     P          QG+Q      
Sbjct: 480 PLQQRPPPQGQQHLSGLGP-PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG 538

Query: 468 -----PLSPQSGSPQQQRSPGSPQLSRASSGSSP-------------------------- 496
                P +    SP  QR  G PQ +R +S S P                          
Sbjct: 539 GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA 598

Query: 497 ---NQASKPGAT------LASQPRPPVQGRSTSQQGEESKKPA-------------PPHP 534
               QAS+ G           QPRP   G +   + + ++KP+             PPHP
Sbjct: 599 GPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658

Query: 535 HLNKSQSLTNSLSTSDTSQ-RGTPSEDEAKAETIRNLRKSFASLFSD 580
            LNKSQSLTN+ +  + +  R + S+DE KAETIR+LRKSFASLFSD
Sbjct: 659 QLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD 705


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score =  595 bits (1533), Expect = e-170
 Identities = 337/629 (53%), Positives = 412/629 (65%), Gaps = 76/629 (12%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49
           MN+LRRRLSDS+FMANLPNGYMTDLQRP             +T  P +   ER      A
Sbjct: 1   MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60

Query: 50  ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98
           AS ++P      G   FSSLS+A+KQ   A +    E  G  +    R     R+LLVID
Sbjct: 61  ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120

Query: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158
           + HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+  GG  VDM+V+RNG KVV RS K
Sbjct: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLK 179

Query: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218
           PDF+L+RQHA+SMA   DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++   L
Sbjct: 180 PDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKL 239

Query: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278
           G E+FPL++QTF+PNHK M+++  +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ K
Sbjct: 240 GTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTK 299

Query: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338
           TYAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 300 TYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDT 359

Query: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQ-LP 397
           CSE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+Q LP
Sbjct: 360 CSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALP 419

Query: 398 MPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQ------PQPRPPPQGGPRQAQSPQPQ 451
                  SP R    Q     SPG   LG Q  Q       Q RPPPQGGP Q   P PQ
Sbjct: 420 RQRQRDASPGRGSHGQ---TPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ-PGPGPQ 475

Query: 452 RSGSPSQQRLSPQGQQPLS---PQSGSPQQQR--SPGSPQLSRASSGSSPNQ-------- 498
           R G P QQR  PQGQQ LS   P +GSP  QR  SP S     AS  + P Q        
Sbjct: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535

Query: 499 -ASKPGATLASQP----------RPPVQGRSTS------------------QQGEESKKP 529
            A  PGA  A++P           PP   R TS                  +QG   K P
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595

Query: 530 APPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
            P  P    SQ+     +   T+Q+  PS
Sbjct: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPS 624



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 5/90 (5%)

Query: 399 PGGTAPS--PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 456
           PGG      P +P  P     +   QA   P+ G P  + P   GP  A  P+PQ +  P
Sbjct: 582 PGGQQRQGPPQKPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP 640

Query: 457 SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQ 486
           SQ    P       P    PQ + SP   Q
Sbjct: 641 SQDVPPPATAAAGGPP--HPQLKASPAQAQ 668



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 6/102 (5%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 456
           P P   + +P      Q    K PG A  GP     Q  P P+ GP   Q P+P  SG  
Sbjct: 572 PAPPKASGAPPGGQQRQGPPQKPPGPA--GPTRQASQAGPVPRTGPPTTQQPRP--SGPG 627

Query: 457 SQQRLSPQGQQPLSPQSGSPQQQRS--PGSPQLSRASSGSSP 496
              R  PQ  Q  S     P    +  P  PQL  + + + P
Sbjct: 628 PAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669


>gi|19924101 synapsin II isoform IIb [Homo sapiens]
          Length = 478

 Score =  573 bits (1478), Expect = e-163
 Identities = 295/484 (60%), Positives = 360/484 (74%), Gaps = 45/484 (9%)

Query: 1   MNFLRRRLSDSSFMANLPNGYMTDLQRPD---------------SSTSSP--ASPAMERR 43
           MNFLRRRLSDSSF+ANLPNGYMTDLQRP+               S++++P  ASP  ERR
Sbjct: 2   MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61

Query: 44  HPQ-----PLAASFSSPGSSLFSSLSSAMKQAPQATSGLMEPPGPSTPIVQRPRILLVID 98
            P      P  A   S GSS FSSLS A+KQ   A++GL++ P P+    ++ ++LLV+D
Sbjct: 62  PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTA-ASAGLVDAPAPAPAAARKAKVLLVVD 120

Query: 99  DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158
           + H DW+K F GKKV G+ +I+VEQAEFSELNL A+  G   VDMQV+RNGTKVV RSF+
Sbjct: 121 EPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV-RSFR 179

Query: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218
           PDF+L+RQHA+ MA  ED+R L+IG+QY GLP++NSL S+YNFC KPWVF+QL+ I+ +L
Sbjct: 180 PDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTL 239

Query: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278
           G EKFPL+EQT++PNHK M+T P FPVVVK+GHAH+GMGK+KVEN  DFQDI SVVA+ +
Sbjct: 240 GGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQ 299

Query: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338
           TYAT E FIDSKYDIR+QKIG+NYKAYMRTSISGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 300 TYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDT 359

Query: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQL-- 396
           CSEMFGGLDICAVKAVH KDG+DYI EVMD SMPLIGEH  EDRQL+ +LV+SKM+QL  
Sbjct: 360 CSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLS 419

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQG-------------GPR 443
             P  +   PL    PQ  + K P  ++  PQ      RPPPQG             GP+
Sbjct: 420 RTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQ------RPPPQGCLQYILDCNGIAVGPK 473

Query: 444 QAQS 447
           Q Q+
Sbjct: 474 QVQA 477



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 9/86 (10%)

Query: 427 PQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQ 486
           P+  QP P PPP  G   A +  P  + SP  +R  P    P S  +  P    S GS  
Sbjct: 29  PEPQQPPPPPPPGPGAASASAAPP--TASPGPERRPP----PASAPAPQPAPTPSVGSSF 82

Query: 487 LSRASSGSSPNQASKPGATLASQPRP 512
            S  S       AS   A L   P P
Sbjct: 83  FSSLSQAVKQTAAS---AGLVDAPAP 105



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 12/78 (15%)

Query: 381 DRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKS-PGQAQLGPQLGQPQPRPPPQ 439
           D   +A+L    M+ L  P    P P  P  P   SA + P  A  GP+      RPPP 
Sbjct: 11  DSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-----RPPP- 64

Query: 440 GGPRQAQSPQPQRSGSPS 457
                A +P PQ + +PS
Sbjct: 65  -----ASAPAPQPAPTPS 77


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 56/175 (32%), Positives = 73/175 (41%), Gaps = 27/175 (15%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLG--PQLGQPQPRPPPQGGPRQAQSP 448
           S+ S  P P   A +PL+   P   S   P QA LG  P L  P P  PP   P + QS 
Sbjct: 752 SQASPAPAPQIPAAAPLKGPGPS-SSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV 810

Query: 449 QPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSS-PNQASKPGATLA 507
                         P  + PL P    P  Q  P  P +    +    P  AS P  T  
Sbjct: 811 S------------RPPSEPPLHP---CPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAP 855

Query: 508 SQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQR---GTPSE 559
             P+PP++ +S   +G     P PP PHL  S + +   S+S+TS R    TPS+
Sbjct: 856 GPPQPPLRPQSQPPEG-----PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 25/179 (13%)

Query: 369 SSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQ 428
           ++ PL G        L     +     LP P  T P    P  PQ  S + P +  L P 
Sbjct: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS-RPPSEPPLHPC 822

Query: 429 LGQPQPRPPPQ-----------GGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQ 477
              P P+ PP            G P  A +P P   G P         Q PL PQS  P+
Sbjct: 823 ---PPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPP---------QPPLRPQSQPPE 870

Query: 478 QQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHL 536
               P +P L  +S+ S+   +S+  + L +      Q +    QG       PP  HL
Sbjct: 871 GPLPP-APHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 45/161 (27%), Positives = 59/161 (36%), Gaps = 24/161 (14%)

Query: 409 PWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGG-PRQAQSPQPQRSGSPSQQR------- 460
           P AP   S   P   Q  PQ  QP   P PQ   P QA +PQP    + S ++       
Sbjct: 625 PQAPPAVSTPLPLGLQQ-PQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPP 683

Query: 461 -------LSPQGQQPLSPQSGSPQQQRSPGSPQLSRASS--GSSPNQASKPGATLASQPR 511
                  L+    Q   PQ  S QQ  S   P LS  +S   S+P  A  P     +   
Sbjct: 684 SATPTAILTQDSLQMFLPQERS-QQPLSAEGPHLSVPASVIVSAPPPAQDP-----APAT 737

Query: 512 PPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTS 552
           P  +G     Q  +S+    P P +  +  L     +S  S
Sbjct: 738 PVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPS 778


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 49/144 (34%), Positives = 60/144 (41%), Gaps = 23/144 (15%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGG--PRQAQSPQPQRSGSP 456
           P G  P P +P  P  +    P   Q  P  G+PQ  PPPQGG   R ++SP  +  G P
Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQG-PPPQGGSKSRSSRSPPGKPQGPP 308

Query: 457 SQQRLSPQGQQP-------LSPQSGS-PQQQRSPGSPQLSRASSGSSPNQASKPGATLAS 508
            Q    PQG  P         PQ G+ PQ    PG PQ      GS    A  P      
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP----PG 364

Query: 509 QPRPPVQGRSTSQQGEESKKPAPP 532
           +P+ P Q     Q+G   + P PP
Sbjct: 365 KPQGPPQ-----QEGNNPQGPPPP 383



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 55/171 (32%), Positives = 66/171 (38%), Gaps = 30/171 (17%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQLGQPQPR-----------PPPQGG- 441
           Q P P G    P      + +SA+SP G+ Q  P  G  QP+           PPPQGG 
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 272

Query: 442 -------PRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ---RSPGSPQLSRAS 491
                  P + Q P PQ  GS S+   SP G+    P  G  Q Q     PG PQ     
Sbjct: 273 KPQGPPPPGKPQGPPPQ-GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331

Query: 492 SGSSPNQASKPGATLASQPRPPVQG--RSTSQQGEESKKPAPPHPHLNKSQ 540
            G+ P     PG        PP QG  +S S +    K   PP    N  Q
Sbjct: 332 GGNKPQGPPPPG----KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQ 378



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 55/182 (30%), Positives = 70/182 (38%), Gaps = 24/182 (13%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGG--PRQAQSPQPQRSGSP 456
           P G  P P +P  P  +    P   Q  P  G+PQ  PPPQG    + A+SP  +  G P
Sbjct: 191 PQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQG-PPPQGDNKSQSARSPPGKPQGPP 246

Query: 457 SQQRLSPQGQQP-------LSPQSGS-PQQQRSPGSPQ-------LSRASSGSSPNQASK 501
            Q    PQG  P         PQ G+ PQ    PG PQ           SS S P +   
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG 306

Query: 502 PGATLASQPR--PPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSE 559
           P     +QP+  PP  G+      +   KP  P P   K Q       +   S R  P +
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGGSKSRSARSPPGK 365

Query: 560 DE 561
            +
Sbjct: 366 PQ 367



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 53/170 (31%), Positives = 63/170 (37%), Gaps = 30/170 (17%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPP-------PQGGPRQAQSPQPQ 451
           P G  P P +P  P  +    P   Q  P  G+PQ  PP       P+  P + Q P PQ
Sbjct: 68  PQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 124

Query: 452 RSGSPSQQRLSPQGQQPLSPQSGS-PQQQRSPGSPQ-------LSRASSGSSPNQASKPG 503
               P      P   Q   PQ G+ PQ    PG PQ           SS S P +   P 
Sbjct: 125 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184

Query: 504 ATLASQPR-----------PPVQGRSTSQQGEESKKP-APPHPHLNKSQS 541
               +QP+           PP QG +  Q      KP  PP    NKSQS
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 52/183 (28%), Positives = 65/183 (35%), Gaps = 15/183 (8%)

Query: 369 SSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPS--PLRPWAPQIKSAKSPGQAQ-L 425
           SS   + E V ++      L+       P  GG  P   P  P  PQ    +   Q Q  
Sbjct: 14  SSAQNLNEDVSQEES--PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP 71

Query: 426 GPQLGQPQPRPP-----PQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ- 479
            P  G+PQ  PP     PQG P   +   P   G  S+   SP G+    P  G  Q Q 
Sbjct: 72  PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131

Query: 480 --RSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLN 537
               PG PQ      G+ P     PG      P P    +S S +    K   PP    N
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189

Query: 538 KSQ 540
           + Q
Sbjct: 190 QPQ 192



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 53/171 (30%), Positives = 66/171 (38%), Gaps = 30/171 (17%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQLGQPQPR-----------PPPQGG- 441
           Q P P G    P      + +S++SP G+ Q  P  G  QP+           PPPQGG 
Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210

Query: 442 -------PRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ---RSPGSPQLSRAS 491
                  P + Q P PQ   + SQ   SP G+    P  G  Q Q     PG PQ     
Sbjct: 211 KPQGPPPPGKPQGPPPQ-GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269

Query: 492 SGSSPNQASKPGATLASQPRPPVQG--RSTSQQGEESKKPAPPHPHLNKSQ 540
            G+ P     PG        PP QG  +S S +    K   PP    N+ Q
Sbjct: 270 GGNKPQGPPPPG----KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 50/144 (34%), Positives = 64/144 (44%), Gaps = 29/144 (20%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQLGQPQPR-----------PPPQGG- 441
           Q P P G    P      + +S++SP G+ Q  P  G  QP+           PPPQGG 
Sbjct: 275 QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 334

Query: 442 -------PRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGS 494
                  P + Q P PQ  GS S+   SP G+    PQ G PQQ+ +  +PQ     +G 
Sbjct: 335 KPQGPPPPGKPQGPPPQ-GGSKSRSARSPPGK----PQ-GPPQQEGN--NPQGPPPPAGG 386

Query: 495 SPNQASKPGA-TLASQPRPPVQGR 517
           +P Q   P A      PRPP  GR
Sbjct: 387 NPQQPQAPPAGQPQGPPRPPQGGR 410



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQL--GQPQPRPPPQGGPRQAQSPQPQ 451
           Q P P G    P      + +SA+SP G+ Q  PQ     PQ  PPP GG    Q PQ  
Sbjct: 337 QGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG--NPQQPQAP 394

Query: 452 RSGSPSQQRLSPQGQQPLSP 471
            +G P      PQG +P  P
Sbjct: 395 PAGQPQGPPRPPQGGRPSRP 414



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 4/87 (4%)

Query: 455 SPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
           SPS    +PQG    +P  G  + Q  P  P   +       NQ   P         PP 
Sbjct: 28  SPSLIAGNPQG----APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 83

Query: 515 QGRSTSQQGEESKKPAPPHPHLNKSQS 541
           QG +  Q      KP  P P  +KS+S
Sbjct: 84  QGGNKPQGPPPPGKPQGPPPQGDKSRS 110


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 55/177 (31%), Positives = 66/177 (37%), Gaps = 22/177 (12%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGG-PRQAQSPQPQRSGSPS 457
           P G  P P +P  P  +    P   Q  P  G+PQ  PPPQG   R  +SP  +  G P 
Sbjct: 47  PQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQ-GPPPQGDKSRSPRSPPGKPQGPPP 102

Query: 458 QQRLSPQGQQP-------LSPQSGS-PQQQRSPGSPQLSRASSGSSPNQASKPGATLASQ 509
           Q    PQG  P         PQ G+ PQ    PG PQ        S +  S PG      
Sbjct: 103 QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 162

Query: 510 PR--------PPVQGRSTSQQGEESKKP-APPHPHLNKSQSLTNSLSTSDTSQRGTP 557
           P+        PP  G+      +  KKP  PP P   +        S S  S  G P
Sbjct: 163 PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 49/144 (34%), Positives = 59/144 (40%), Gaps = 24/144 (16%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGG--PRQAQSPQPQRSGSP 456
           P G  P P +P  P  +  K P   Q  P  G+PQ   PP  G   R +QSP  +  G P
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKP---QGPPPPGKPQG--PPPQGDKSRSSQSPPGKPQGPP 223

Query: 457 SQQRLSPQGQQP-------LSPQSGS-PQQQRSPGSPQLSRASSGSSPNQASKPGATLAS 508
            Q    PQG  P         PQ G+ PQ    PG PQ   A  GS    A  P      
Sbjct: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP----PG 279

Query: 509 QPRPPVQGRSTSQQGEESKKPAPP 532
           +P+ P Q     Q+G   + P PP
Sbjct: 280 KPQGPPQ-----QEGNNPQGPPPP 298



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 52/147 (35%), Positives = 66/147 (44%), Gaps = 30/147 (20%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQLGQPQPR-----------PPPQ 439
           K  Q P P G    P  P   + +S++SP G+ Q  P  G  QP+           PPPQ
Sbjct: 188 KKPQGPPPPGKPQGP-PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246

Query: 440 GG--------PRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRAS 491
           GG        P + Q P P + GS SQ   SP G+    PQ G PQQ+ +  +PQ     
Sbjct: 247 GGNKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGK----PQ-GPPQQEGN--NPQGPPPP 298

Query: 492 SGSSPNQASKPGA-TLASQPRPPVQGR 517
           +G +P Q   P A      PRPP  GR
Sbjct: 299 AGGNPQQPQAPPAGQPQGPPRPPQGGR 325



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 51/155 (32%), Positives = 59/155 (38%), Gaps = 20/155 (12%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG 454
           Q P P G    P     PQ   ++SP      PQ   PQ    PQG P     PQ    G
Sbjct: 69  QGPPPPGKPQGP----PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ----G 120

Query: 455 SPSQQRLSPQGQQPL-SPQSGSPQQQRS------PGSPQLSRASSGSSPNQASKPGATLA 507
            P Q    PQG  P   PQ   PQ  +S      PG PQ      G+ P     P     
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP----P 176

Query: 508 SQPR-PPVQGRSTSQQGEESKKPAPPHPHLNKSQS 541
            +P+ PP QG    Q      KP  P P  +KS+S
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRS 211



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 53/176 (30%), Positives = 60/176 (34%), Gaps = 36/176 (20%)

Query: 397 PMPGGTAPS----PLRPWAPQIKSAKS------PGQAQLGPQLG--QPQPRPP------- 437
           P  GG  P     P +P  P  +  KS      PG+ Q  P  G  QPQ  PP       
Sbjct: 122 PPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 181

Query: 438 --------PQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ---RSPGSPQ 486
                   PQG P   +   P   G  S+   SP G+    P  G  Q Q     PG PQ
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241

Query: 487 LSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEE--SKKPAPPHPHLNKSQ 540
                 G+ P     PG        PP QG S SQ       K   PP    N  Q
Sbjct: 242 GPPPQGGNKPQGPPPPG----KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 52/174 (29%), Positives = 60/174 (34%), Gaps = 33/174 (18%)

Query: 397 PMPGGTAPS----PLRPWAPQIKSAKS------PGQAQLGPQLG--QPQPRPP------- 437
           P  GG  P     P +P  P  +  KS      PG+ Q  P  G  QPQ  PP       
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120

Query: 438 --------PQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ---RSPGSPQ 486
                   PQG P   +   P   G  S+   SP G+    P  G  Q Q     PG PQ
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180

Query: 487 LSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQ 540
                 G  P     PG     Q  PP   +S S Q    K   PP    N+ Q
Sbjct: 181 GPPPQGGKKPQGPPPPG---KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ 231



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 44/136 (32%), Positives = 53/136 (38%), Gaps = 16/136 (11%)

Query: 414 IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPL-SPQ 472
           +   +SP      PQ   PQ    PQG P     PQ    G P Q    PQG  P   PQ
Sbjct: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ----GPPPQGGNKPQGPPPPGKPQ 78

Query: 473 SGSPQQQRS------PGSPQLSRASSGSSPNQASKPGATLASQPR-PPVQGRSTSQQGEE 525
              PQ  +S      PG PQ      G+ P     P      +P+ PP QG +  Q    
Sbjct: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGNRPQGPPP 134

Query: 526 SKKPAPPHPHLNKSQS 541
             KP  P P  +KS+S
Sbjct: 135 PGKPQGPPPQGDKSRS 150



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQL--GQPQPRPPPQGGPRQAQSPQPQ 451
           Q P P G    P      + +SA+SP G+ Q  PQ     PQ  PPP GG    Q PQ  
Sbjct: 252 QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG--NPQQPQAP 309

Query: 452 RSGSPSQQRLSPQGQQPLSP 471
            +G P      PQG +P  P
Sbjct: 310 PAGQPQGPPRPPQGGRPSRP 329



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 8/65 (12%)

Query: 391 SKMSQLPMPGGTAPSPLR-----PWAPQIKSAKSPGQAQLGPQLGQPQ-PRPPPQGGPRQ 444
           SK      P G    P +     P  P   +  +P Q Q  P  GQPQ P  PPQGG R 
Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ-APPAGQPQGPPRPPQGG-RP 326

Query: 445 AQSPQ 449
           ++ PQ
Sbjct: 327 SRPPQ 331


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 44/140 (31%), Positives = 59/140 (42%), Gaps = 16/140 (11%)

Query: 401 GTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ--------- 451
           GT P P +P  P  +      +    P  G+P+ RPPPQGG  Q+Q P P          
Sbjct: 112 GTPPPPGKPERPPPQGGNQSHRPP--PPPGKPE-RPPPQGG-NQSQGPPPHPGKPEGPPP 167

Query: 452 RSGSPSQQRLSPQG--QQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQ 509
           + G+ S+   SP G  Q P   +   PQ    PG PQ     +G +P Q   P A     
Sbjct: 168 QEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQ-GPPPAGGNPQQPQAPPAGKPQG 226

Query: 510 PRPPVQGRSTSQQGEESKKP 529
           P PP QG    +  +  + P
Sbjct: 227 PPPPPQGGRPPRPAQGQQPP 246



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 51/184 (27%), Positives = 64/184 (34%), Gaps = 14/184 (7%)

Query: 369 SSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPS--PLRPWAPQIKSAKSPGQAQ-L 425
           SS     E V ++  L   L+  K       GG  P   P  P  PQ    +   Q+Q  
Sbjct: 14  SSAESSSEDVSQEESLF--LISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGP 71

Query: 426 GPQLGQPQPRPPPQGGPRQAQSPQPQR-------SGSPSQQRLSPQGQQPLSPQSGSPQQ 478
            P  G+P+ RPP  G   Q   P P +        G+ SQ    P G+    P  G  Q 
Sbjct: 72  PPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS 131

Query: 479 QRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQ--GRSTSQQGEESKKPAPPHPHL 536
            R P  P           NQ+  P         PP Q   +S S +    K   PP    
Sbjct: 132 HRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEG 191

Query: 537 NKSQ 540
           NK Q
Sbjct: 192 NKPQ 195



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 13/126 (10%)

Query: 427 PQLGQPQPRPPPQGGPRQAQSPQP---QRSGSPSQQRLSPQGQQP------LSPQSGSPQ 477
           P  G+PQ  PPPQGG  Q+Q P P   +  G P Q     QG  P        P  G  Q
Sbjct: 52  PPPGKPQG-PPPQGG-NQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQ 109

Query: 478 QQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQ--QGEESKKPAPPHPH 535
            Q +P  P           NQ+ +P        RPP QG + SQ       K   PP   
Sbjct: 110 SQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQE 169

Query: 536 LNKSQS 541
            NKS+S
Sbjct: 170 GNKSRS 175



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 47/156 (30%), Positives = 60/156 (38%), Gaps = 26/156 (16%)

Query: 397 PMPGGTAPS--PLRPWAPQIKSAKSPGQAQ-LGPQLGQPQPRPPPQGGPRQAQSPQPQRS 453
           P  GG      P  P  P+    +   Q+Q   P  G+P+ RPPPQGG +  + P P   
Sbjct: 82  PPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPE-RPPPQGGNQSHRPPPP--P 138

Query: 454 GSPSQQRLSPQG--------QQPLSPQSGSPQQ-------QRSPGSPQLSRASSGSSPNQ 498
           G P  +R  PQG          P  P+   PQ+       +  PG PQ      G+ P  
Sbjct: 139 GKP--ERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQG 196

Query: 499 ASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHP 534
              PG     Q  PP  G     Q   + KP  P P
Sbjct: 197 PPPPG---KPQGPPPAGGNPQQPQAPPAGKPQGPPP 229



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 46/154 (29%), Positives = 64/154 (41%), Gaps = 27/154 (17%)

Query: 395 QLPMPGGTAPS---PLRPWAPQIKSAKSPGQAQ-LGPQLGQPQPRPPPQGG--------- 441
           Q P P G   S   P  P  P+ +  +   Q+Q   P  G+P+ RPPPQGG         
Sbjct: 58  QGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPE-RPPPQGGNQSQGTPPP 116

Query: 442 PRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ---RSPGSPQLSRASSGSSPNQ 498
           P + + P PQ  G+ S +   P G+    P  G  Q Q     PG P+      G+    
Sbjct: 117 PGKPERPPPQ-GGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRS 175

Query: 499 ASKPGATLASQPRPPVQGRSTSQQGEESKKPAPP 532
           A  P      +P+ P Q     Q+G + + P PP
Sbjct: 176 ARSP----PGKPQGPPQ-----QEGNKPQGPPPP 200



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 21/97 (21%)

Query: 401 GTAPSPLRPWAP------QIKSAKSP-GQAQLGPQL-----------GQPQPRPPPQGGP 442
           G  P P +P  P      + +SA+SP G+ Q  PQ            G+PQ  PP  G P
Sbjct: 154 GPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP 213

Query: 443 RQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQ 479
           +Q Q+P    +G P      PQG +P  P  G    Q
Sbjct: 214 QQPQAP---PAGKPQGPPPPPQGGRPPRPAQGQQPPQ 247



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 23/55 (41%), Positives = 25/55 (45%), Gaps = 15/55 (27%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQ-PRPPPQGG--PRQAQSPQP 450
           P G  P+   P  PQ             P  G+PQ P PPPQGG  PR AQ  QP
Sbjct: 203 PQGPPPAGGNPQQPQ------------APPAGKPQGPPPPPQGGRPPRPAQGQQP 245


>gi|58530845 zyxin [Homo sapiens]
          Length = 572

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 56/173 (32%), Positives = 70/173 (40%), Gaps = 37/173 (21%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLG-----------QPQPRPPPQ 439
           SK S  P  GGTAP P  PW       KSP  +Q  PQ+            QPQP+P PQ
Sbjct: 183 SKSSTKPAAGGTAPLP--PW-------KSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQ 233

Query: 440 GGPRQAQSPQP------QRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSG 493
                    QP      Q  G P+          P++P+      + SPG+P      SG
Sbjct: 234 VQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAP----GGSG 289

Query: 494 SSPNQ-ASKPGATLASQPRPPVQGRSTSQQGE-----ESKKPAPPHPHLNKSQ 540
           S PNQ    P A  A    P     + +QQ E     E + P PP P  N++Q
Sbjct: 290 SQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPP-PAQNQNQ 341



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 51/203 (25%), Positives = 73/203 (35%), Gaps = 37/203 (18%)

Query: 400 GGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ-------- 451
           GG  P P  P       A  P + ++ P    P P P  +GGP     P PQ        
Sbjct: 90  GGAFPPPPPPIEESFPPA--PLEEEIFPS---PPPPPEEEGGPEAPIPPPPQPREKVSSI 144

Query: 452 --------------RSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPN 497
                             P + R+S  G  P  P   +P   +S   P    A+ G++P 
Sbjct: 145 DLEIDSLSSLLDDMTKNDPFKARVS-SGYVP--PPVATPFSSKSSTKP----AAGGTAPL 197

Query: 498 QASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLN-KSQSLTNSLSTSDTSQRGT 556
              K  +  +SQP P V   + SQ     +    P P +    QS T  +S ++T  RG 
Sbjct: 198 PPWK--SPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGP 255

Query: 557 PSEDEAKAETIRNLRKSFASLFS 579
           P+   A A     +   F  + S
Sbjct: 256 PASSPAPAPKFSPVTPKFTPVAS 278



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 15/123 (12%)

Query: 372 PLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAP----SPLRPWAPQIKSAKSPGQ----- 422
           P +  HV+   Q ++  + +   + P     AP    SP+ P    + S  SPG      
Sbjct: 232 PQVQLHVQSQTQPVS--LANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSG 289

Query: 423 AQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSP 482
           +Q   +LG P+      G P+       Q+   P  Q    + Q P+ P + +  Q RSP
Sbjct: 290 SQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQ----EKQHPVPPPAQNQNQVRSP 345

Query: 483 GSP 485
           G+P
Sbjct: 346 GAP 348


>gi|4508047 zyxin [Homo sapiens]
          Length = 572

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 56/173 (32%), Positives = 70/173 (40%), Gaps = 37/173 (21%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLG-----------QPQPRPPPQ 439
           SK S  P  GGTAP P  PW       KSP  +Q  PQ+            QPQP+P PQ
Sbjct: 183 SKSSTKPAAGGTAPLP--PW-------KSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQ 233

Query: 440 GGPRQAQSPQP------QRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSG 493
                    QP      Q  G P+          P++P+      + SPG+P      SG
Sbjct: 234 VQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAP----GGSG 289

Query: 494 SSPNQ-ASKPGATLASQPRPPVQGRSTSQQGE-----ESKKPAPPHPHLNKSQ 540
           S PNQ    P A  A    P     + +QQ E     E + P PP P  N++Q
Sbjct: 290 SQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPP-PAQNQNQ 341



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 51/203 (25%), Positives = 73/203 (35%), Gaps = 37/203 (18%)

Query: 400 GGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ-------- 451
           GG  P P  P       A  P + ++ P    P P P  +GGP     P PQ        
Sbjct: 90  GGAFPPPPPPIEESFPPA--PLEEEIFPS---PPPPPEEEGGPEAPIPPPPQPREKVSSI 144

Query: 452 --------------RSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPN 497
                             P + R+S  G  P  P   +P   +S   P    A+ G++P 
Sbjct: 145 DLEIDSLSSLLDDMTKNDPFKARVS-SGYVP--PPVATPFSSKSSTKP----AAGGTAPL 197

Query: 498 QASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLN-KSQSLTNSLSTSDTSQRGT 556
              K  +  +SQP P V   + SQ     +    P P +    QS T  +S ++T  RG 
Sbjct: 198 PPWK--SPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGP 255

Query: 557 PSEDEAKAETIRNLRKSFASLFS 579
           P+   A A     +   F  + S
Sbjct: 256 PASSPAPAPKFSPVTPKFTPVAS 278



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 15/123 (12%)

Query: 372 PLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAP----SPLRPWAPQIKSAKSPGQ----- 422
           P +  HV+   Q ++  + +   + P     AP    SP+ P    + S  SPG      
Sbjct: 232 PQVQLHVQSQTQPVS--LANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSG 289

Query: 423 AQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSP 482
           +Q   +LG P+      G P+       Q+   P  Q    + Q P+ P + +  Q RSP
Sbjct: 290 SQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQ----EKQHPVPPPAQNQNQVRSP 345

Query: 483 GSP 485
           G+P
Sbjct: 346 GAP 348


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 47/163 (28%), Positives = 67/163 (41%), Gaps = 14/163 (8%)

Query: 402 TAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ------RSGS 455
           ++P PL P  P   S      + L P+    + RPP     RQ Q+   +      R  S
Sbjct: 717 SSPPPLPPPPPMSPSWSERSVSPLRPET---EARPPS----RQLQALLARNIINAARRKS 769

Query: 456 PSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQ 515
            S +    +  +P SP    P     P  P   R+   + P  A+ PGA  A  PR P+ 
Sbjct: 770 ASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLP 829

Query: 516 GRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
              +S     S  PAPP P L + +S T+S  + D+   G  S
Sbjct: 830 AGPSSCTSPRSPLPAPPRPFLYR-RSPTDSDVSLDSEDSGAKS 871



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 56/212 (26%), Positives = 80/212 (37%), Gaps = 45/212 (21%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQ--------PRPPPQGGPRQAQSP 448
           P P    P  LRP    +   K P  A++ P+   P         P  P    P     P
Sbjct: 557 PEPTKQPPYQLRPSLFVLSPIKEP--AKVSPRAASPAKPSSLDLVPNLPKGALPPSPALP 614

Query: 449 QPQRSG-----SPSQQRLSPQGQQP-----LSP----QSGSPQQQRSPGSPQLSRASSG- 493
           +P RS      SP Q  L P    P     +SP    ++ SP+ +++P  P  S  ++G 
Sbjct: 615 RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAP-RPSFSTRNAGI 673

Query: 494 -------SSPNQ------ASKPGATLAS--QPRPPVQGRSTSQQGEESKKPAPPHPHLNK 538
                  S P        AS+P ++L     P P   GR +S     S  P PP P ++ 
Sbjct: 674 EAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSM---SSPPPLPPPPPMSP 730

Query: 539 SQSLTNSLSTSDTSQRGTPSEDEAKAETIRNL 570
           S S   S+S         P   + +A   RN+
Sbjct: 731 SWS-ERSVSPLRPETEARPPSRQLQALLARNI 761


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 46/137 (33%), Positives = 55/137 (40%), Gaps = 18/137 (13%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSP 463
           PSP     PQ      PG+ Q  P  G  +P+ PP  G  Q   PQ  +S SP      P
Sbjct: 39  PSPQGGNKPQ-GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97

Query: 464 QGQQPLS-------PQSGS-PQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQ 515
           QG  P         PQ G+ PQ    PG PQ   A  GS    A  P      +P+ P Q
Sbjct: 98  QGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP----PGKPQGPPQ 153

Query: 516 GRSTSQQGEESKKPAPP 532
                Q+G   + P PP
Sbjct: 154 -----QEGNNPQGPPPP 165



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 50/140 (35%), Positives = 61/140 (43%), Gaps = 27/140 (19%)

Query: 397 PMPGGTAPS----PLRPWAPQIKSAKS------PGQAQLGPQLGQPQPRPPPQGG----- 441
           P  GG  P     P +P  P  +  KS      PG+ Q  P  G     PPPQGG     
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQG 120

Query: 442 ---PRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQ 498
              P + Q P P + GS SQ   SP G+    PQ G PQQ+ +  +PQ     +G +P Q
Sbjct: 121 PPPPGKPQGP-PAQGGSKSQSARSPPGK----PQ-GPPQQEGN--NPQGPPPPAGGNPQQ 172

Query: 499 ASKPGA-TLASQPRPPVQGR 517
              P A      PRPP  GR
Sbjct: 173 PQAPPAGQPQGPPRPPQGGR 192



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 28/155 (18%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSP------GQAQLGPQLGQP--QPRPP---PQGGPRQAQS 447
           P G  P P +P  P  +    P      G+ Q  P  G     PR P   PQG P Q   
Sbjct: 47  PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGK 106

Query: 448 PQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRS--------PGSPQLSRASSGSSPNQA 499
           PQ    G P Q    PQG  P     G P Q  S        PG PQ      G++P   
Sbjct: 107 PQ----GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 162

Query: 500 SKPGATLASQPRPPVQGRSTS-----QQGEESKKP 529
             P      QP+ P  G+        Q G  S+ P
Sbjct: 163 PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 42/157 (26%), Positives = 51/157 (32%), Gaps = 12/157 (7%)

Query: 414 IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQS 473
           +   +SP      PQ   PQ    PQG P     PQ    G P Q    PQG  P     
Sbjct: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ----GPPPQGGNKPQGPPPPGKPQ 78

Query: 474 GSPQQQRSPGSPQLSRASSGSSPNQASKP------GATLASQPRPPVQGRSTSQQGEESK 527
           G P Q     SP+         P Q  KP      G      P PP + +    QG    
Sbjct: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKS 138

Query: 528 KPA--PPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEA 562
           + A  PP       Q   N+         G P + +A
Sbjct: 139 QSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 175



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQL--GQPQPRPPPQGGPRQAQSPQPQ 451
           Q P P G    P      + +SA+SP G+ Q  PQ     PQ  PPP GG    Q PQ  
Sbjct: 119 QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG--NPQQPQAP 176

Query: 452 RSGSPSQQRLSPQGQQPLSP 471
            +G P      PQG +P  P
Sbjct: 177 PAGQPQGPPRPPQGGRPSRP 196



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 8/65 (12%)

Query: 391 SKMSQLPMPGGTAPSPLR-----PWAPQIKSAKSPGQAQLGPQLGQPQ-PRPPPQGGPRQ 444
           SK      P G    P +     P  P   +  +P Q Q  P  GQPQ P  PPQGG R 
Sbjct: 136 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ-APPAGQPQGPPRPPQGG-RP 193

Query: 445 AQSPQ 449
           ++ PQ
Sbjct: 194 SRPPQ 198


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 48/136 (35%), Positives = 58/136 (42%), Gaps = 27/136 (19%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPP--------------PQGGPRQ 444
           P G  P P +P  P  +    P   Q  P  G+PQ  PP              PQG P Q
Sbjct: 47  PQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 103

Query: 445 AQSPQ--PQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKP 502
              PQ  P + GS SQ   SP G+    PQ G PQQ+ +  +PQ     +G +P Q   P
Sbjct: 104 GGKPQGPPAQGGSKSQSARSPPGK----PQ-GPPQQEGN--NPQGPPPPAGGNPQQPQAP 156

Query: 503 GA-TLASQPRPPVQGR 517
            A      PRPP  GR
Sbjct: 157 PAGQPQGPPRPPQGGR 172



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 41/117 (35%), Positives = 54/117 (46%), Gaps = 17/117 (14%)

Query: 397 PMPGGTAPS----PLRPWAPQIKSAKS------PGQAQLGPQLGQPQPRPPPQGGPRQ-- 444
           P  GG  P     P +P  P  +  KS      PG+ Q  P  G     PP QGG +   
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQS 120

Query: 445 AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSP--GSPQ-LSRASSGSSPNQ 498
           A+SP  +  G P Q+  +PQG  P  P  G+PQQ ++P  G PQ   R   G  P++
Sbjct: 121 ARSPPGKPQGPPQQEGNNPQGPPP--PAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 175



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 45/140 (32%), Positives = 56/140 (40%), Gaps = 15/140 (10%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP-----SQ 458
           PSP     PQ      PG+ Q  P  G  +P+ PP  G  Q   PQ  +S SP       
Sbjct: 39  PSPQGGNKPQ-GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97

Query: 459 QRLSPQGQQPLSP--QSGSPQQ--QRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
           Q   PQG +P  P  Q GS  Q  +  PG PQ      G++P     P      QP+ P 
Sbjct: 98  QGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 157

Query: 515 QGRSTS-----QQGEESKKP 529
            G+        Q G  S+ P
Sbjct: 158 AGQPQGPPRPPQGGRPSRPP 177



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 37/110 (33%), Positives = 46/110 (41%), Gaps = 9/110 (8%)

Query: 427 PQLG-QPQPRPPPQGGPRQAQSPQPQRSGSPS--QQRLSPQGQQPLSPQSGSPQQQRSPG 483
           PQ G +PQ  PPP G P   Q P PQ    P        PQG  P   +S SP+    PG
Sbjct: 41  PQGGNKPQGPPPPPGKP---QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS--PPG 95

Query: 484 SPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQ-GEESKKPAPP 532
            PQ      G      ++ G+   S   PP + +   QQ G   + P PP
Sbjct: 96  KPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 145



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 40/134 (29%), Positives = 44/134 (32%), Gaps = 24/134 (17%)

Query: 414 IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQS 473
           +   +SP      PQ   PQ    PQG P     PQ    G P Q    PQG  P     
Sbjct: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ----GPPPQGGNKPQGPPPPGKPQ 78

Query: 474 GSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQ------------ 521
           G P Q     SP+         P Q  KP         PP QG S SQ            
Sbjct: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGKPQG-------PPAQGGSKSQSARSPPGKPQGP 131

Query: 522 -QGEESKKPAPPHP 534
            Q E +    PP P
Sbjct: 132 PQQEGNNPQGPPPP 145



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/78 (37%), Positives = 35/78 (44%), Gaps = 5/78 (6%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSP-GQAQLGPQL--GQPQPRPPPQGGPRQAQSPQPQRS 453
           P  GG    P      + +SA+SP G+ Q  PQ     PQ  PPP GG    Q PQ   +
Sbjct: 101 PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG--NPQQPQAPPA 158

Query: 454 GSPSQQRLSPQGQQPLSP 471
           G P      PQG +P  P
Sbjct: 159 GQPQGPPRPPQGGRPSRP 176



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 9/109 (8%)

Query: 455 SPSQQRLSPQGQQPLSPQSGSPQQ--QRSPGSPQLSRASSGSSPNQASKPGATLASQPRP 512
           SPS    +PQG    SPQ G+  Q     PG PQ      G+ P     PG        P
Sbjct: 28  SPSLIAGNPQGP---SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG----P 80

Query: 513 PVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDE 561
           P QG  +        KP  P P   K Q       +   S R  P + +
Sbjct: 81  PPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQ 129



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 8/65 (12%)

Query: 391 SKMSQLPMPGGTAPSPLR-----PWAPQIKSAKSPGQAQLGPQLGQPQ-PRPPPQGGPRQ 444
           SK      P G    P +     P  P   +  +P Q Q  P  GQPQ P  PPQGG R 
Sbjct: 116 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ-APPAGQPQGPPRPPQGG-RP 173

Query: 445 AQSPQ 449
           ++ PQ
Sbjct: 174 SRPPQ 178


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 47/128 (36%), Positives = 58/128 (45%), Gaps = 18/128 (14%)

Query: 401 GTAPSPLRPWAPQIKSA-KSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRS---GSP 456
           G  P P +P  P  +   +S G     P+ G+P+  PPPQGG  Q+Q P P+     G P
Sbjct: 175 GPPPHPGKPEGPPPQGGNQSQGPP---PRPGKPEG-PPPQGG-NQSQGPPPRPGKPEGPP 229

Query: 457 SQQRLSPQGQQPLS-------PQSGS-PQQQRSPGSPQLSRASSGSSPNQASKPGATLAS 508
           SQ    PQG  P         PQ G+ PQ+   PG PQ      G +P Q   P A    
Sbjct: 230 SQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ-GPPPPGGNPQQPLPPPAGKPQ 288

Query: 509 QPRPPVQG 516
            P PP QG
Sbjct: 289 GPPPPPQG 296



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 52/168 (30%), Positives = 65/168 (38%), Gaps = 26/168 (15%)

Query: 397 PMPGGTAPS--PLRPWAPQIKSAKSPGQAQ-LGPQLGQPQPRPPPQGGPRQAQSPQPQRS 453
           P  GG      P RP  P+ +  +   Q+Q   P+ G+P+  PPPQGG  Q+Q P P+  
Sbjct: 82  PPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEG-PPPQGG-NQSQGPPPRPG 139

Query: 454 ---GSPSQQRLSPQGQQPLS------PQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGA 504
              G P Q     QG  P        P  G  Q Q  P  P           NQ+  P  
Sbjct: 140 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP 199

Query: 505 TLASQPRPPVQGRSTSQ---------QGEESK---KPAPPHPHLNKSQ 540
                  PP QG + SQ         +G  S+   KP  P PH  K Q
Sbjct: 200 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQ 247



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQ 458
           P G  P P +P  P  +    P   Q  P  G+PQ  PPP G P+Q   P P  +G P  
Sbjct: 236 PQGPPPHPGKPQGPPPQEGNKP---QRPPPPGRPQGPPPPGGNPQQ---PLPPPAGKPQG 289

Query: 459 QRLSPQGQQPLSPQSGSPQQ 478
               PQG +P  P  G P Q
Sbjct: 290 PPPPPQGGRPHRPPQGQPPQ 309



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 46/147 (31%), Positives = 61/147 (41%), Gaps = 21/147 (14%)

Query: 400 GGTAP--SPLRPWAPQIKSAKSPGQAQ-LGPQLGQPQPRPPPQGGPRQAQSP-------- 448
           GG  P  +P  P  P+ +  +   Q+Q   P+ G+P+  PPPQGG  Q+Q P        
Sbjct: 43  GGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEG-PPPQGG-NQSQGPPPRPGKPE 100

Query: 449 -QPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLA 507
            QP + G+ SQ      G+    P  G  Q Q  P  P           NQ+  P     
Sbjct: 101 GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 160

Query: 508 SQPRPPVQGRSTSQQGEESKKPAPPHP 534
               PP QG      G +S+ P PPHP
Sbjct: 161 KPEGPPPQG------GNQSQGP-PPHP 180



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 46/161 (28%), Positives = 62/161 (38%), Gaps = 19/161 (11%)

Query: 397 PMPGGTAPS--PLRPWAPQIKSAKSPGQAQ-LGPQLGQPQPRPPPQGGPRQAQSPQPQ-- 451
           P  GG      P RP  P+    +   Q+Q   P+ G+P+  PPPQGG  Q+Q P P   
Sbjct: 124 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGG-NQSQGPPPHPG 181

Query: 452 -------RSGSPSQQRLSPQGQQPLSPQSGSPQQQ---RSPGSPQLSRASSGSSPNQASK 501
                  + G+ SQ      G+    P  G  Q Q     PG P+   +  G+ P     
Sbjct: 182 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQ--GP 239

Query: 502 PGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSL 542
           P      Q  PP +G    +     +   PP P  N  Q L
Sbjct: 240 PPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPL 280



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 26/61 (42%), Positives = 27/61 (44%), Gaps = 10/61 (16%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPG---QAQLGPQLGQPQ-PRPPPQGG----PRQAQSP 448
           P  G     P  P  PQ      PG   Q  L P  G+PQ P PPPQGG    P Q Q P
Sbjct: 251 PQEGNKPQRPPPPGRPQ--GPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308

Query: 449 Q 449
           Q
Sbjct: 309 Q 309



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 29/132 (21%)

Query: 411 APQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLS 470
           +P + S K  G+   G    QPQ  PPP G P           G P Q     QG  P  
Sbjct: 28  SPSVISGKPEGRRPQGGN--QPQRTPPPPGKPE----------GRPPQGGNQSQGPPP-- 73

Query: 471 PQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQ--QGEESKK 528
            + G P+     G P      S   P +  KP      + +PP QG + SQ       K 
Sbjct: 74  -RPGKPE-----GPPPQGGNQSQGPPPRPGKP------EGQPP-QGGNQSQGPPPRPGKP 120

Query: 529 PAPPHPHLNKSQ 540
             PP    N+SQ
Sbjct: 121 EGPPPQGGNQSQ 132



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 6/83 (7%)

Query: 457 SQQRLSPQGQQPLSPQ--SGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
           S Q L+    Q  SP   SG P+ +R  G  Q  R        +   P     SQ  PP 
Sbjct: 15  SAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPR 74

Query: 515 QGRSTS---QQGEESKKPAPPHP 534
            G+      Q G +S+ P PP P
Sbjct: 75  PGKPEGPPPQGGNQSQGP-PPRP 96


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 45/144 (31%), Positives = 62/144 (43%), Gaps = 15/144 (10%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRP---PPQGGPRQAQSPQPQRSGS 455
           P GT   P +P  P    A+  G  +  P   QP P+    PP  G   AQ P P +   
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEK--PSSEQPGPKALAQPPGVGKTPAQQPGPAKP-- 410

Query: 456 PSQQRLSPQGQQPLSPQSG--SPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQ---P 510
           P+QQ  +P+   PL+ Q G  SP +   P    + +   G  P Q + PG T A Q    
Sbjct: 411 PTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467

Query: 511 RPPVQGRSTSQQGEESKKPAPPHP 534
           +PP Q    ++   +   PA P P
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPP 491



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 16/141 (11%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG 454
           Q P PG     P +   P   SA+  G  +   QL  P   PP Q GP +   P PQ+ G
Sbjct: 442 QQPGPGKI---PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK---PPPQQPG 495

Query: 455 SPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQ---ASKPGATLASQPR 511
           S       P  QQP S +   P QQ  P  P   +  S   P+Q   ++KP A   S  +
Sbjct: 496 SAK-----PPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548

Query: 512 PPVQGRSTSQQGEESKKPAPP 532
           P  Q  +       S KP  P
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQP 569



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 12/180 (6%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQR--L 461
           P PL         AK+PG  +   Q   P   P  Q GP +  + Q   +  PSQ     
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477

Query: 462 SPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQ 521
            P  QQP  P    PQQ   PGS +      GS+     +PG    S P+ P   +  SQ
Sbjct: 478 KPPPQQP-GPAKPPPQQ---PGSAKPPSQQPGSTKPPPQQPGPAKPS-PQQPGSTKPPSQ 532

Query: 522 QGEESK----KPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASL 577
           Q   +K    +P+P  P   +S    +   +    Q  T S   AK    + L K+   L
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-PSAKQPPSQGLPKTICPL 591



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 41/131 (31%), Positives = 53/131 (40%), Gaps = 16/131 (12%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQ 458
           PG T+     P  P    ++ PG A+  PQ   P   PP Q G  +  S QP  +  P Q
Sbjct: 456 PGKTSAQQTGPTKPP---SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 459 QR--LSPQGQQPLSPQSGSPQ--------QQRSPGSPQLSRASSGSSPNQASK---PGAT 505
           Q     P  QQP S +  S Q        QQ SP  P   +++   S   + K   P   
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572

Query: 506 LASQPRPPVQG 516
             S  +PP QG
Sbjct: 573 SPSAKQPPSQG 583



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 51/183 (27%), Positives = 72/183 (39%), Gaps = 27/183 (14%)

Query: 393 MSQLPMPGGTA---PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSP- 448
           ++Q P  G T    P P +P   Q+ + K   Q    P L  P   P P   P Q   P 
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ---PGLQSPAKAPGPTKTPVQQPGPG 447

Query: 449 ----QPQRSGSPSQQRLSP-QGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPG 503
               Q    G  S Q+  P +    L   +  P QQ  P  P   +  S   P+Q  +PG
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ--QPG 505

Query: 504 ATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAK 563
           +T     +PP Q     Q G    KP+P  P   K  S     S   ++Q+ +P++  A+
Sbjct: 506 ST-----KPPPQ-----QPG--PAKPSPQQPGSTKPPSQQPG-SAKPSAQQPSPAKPSAQ 552

Query: 564 AET 566
             T
Sbjct: 553 QST 555



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 52/170 (30%), Positives = 68/170 (40%), Gaps = 37/170 (21%)

Query: 399 PGGTAPSPLRPWAPQ-IKSAKSPGQAQLGPQLGQP------QP-----RPPPQGGPRQA- 445
           P G    PL+   P+ I   + PG+  L  Q G P      QP     +PP  G P Q  
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPL-QQDGTPKSISSQQPEKIKSQPPGTGKPIQGP 261

Query: 446 -QSPQPQRSGSPSQQRLS-PQGQQP-----------LSPQSGSPQQQRSPGSPQLSRASS 492
            Q+PQ   +  P Q+  S PQ +Q            L   S  P QQ +PG P   +   
Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH 321

Query: 493 GSSPNQASKPGAT-------LASQP---RPPVQGRSTSQQGEESKKPAPP 532
             S    +KP A        LA QP   +PPVQ   T++   +   PA P
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP 371



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 8/151 (5%)

Query: 400 GGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQ 459
           G  AP P  P  P++K+A     + +     QPQ     Q  P++  +P+   S +P  +
Sbjct: 648 GDLAPVPSSP-QPKLKTAPVTTTSAVSKSSPQPQ-----QTSPKKDAAPKQDLSKAPEPK 701

Query: 460 RLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASK--PGATLASQPRPPVQGR 517
           +  P  +QP    S S + ++ P +  LS+ +    P+  S+         +P+ P   +
Sbjct: 702 KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761

Query: 518 STSQQGEESKKPAPPHPHLNKSQSLTNSLST 548
            T+     S     P    +K QS     +T
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 40/148 (27%), Positives = 59/148 (39%), Gaps = 21/148 (14%)

Query: 401 GTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGS--PSQ 458
           G A  P +P       A+ PG  +  P +  P    PP   P     P  Q++GS  PS 
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVK--PPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSS 383

Query: 459 QRLSPQGQQPLSPQSGSPQQQRSPGSP---------QLSRASSGSSPNQASKPGATLASQ 509
           ++  P+          +P QQ  P  P          L++     SP +A  P  T   Q
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443

Query: 510 PRP---PVQ----GRSTSQQGEESKKPA 530
           P P   P Q    G++++QQ   +K P+
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPS 471



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 38/150 (25%), Positives = 53/150 (35%), Gaps = 16/150 (10%)

Query: 412 PQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSP 471
           PQ K A       + P L  P P  PP       Q P P +   P+QQ    + Q   + 
Sbjct: 281 PQTKQADIVRGESVKPSL--PSPSKPP------IQQPTPGK--PPAQQPGHEKSQPGPAK 330

Query: 472 QSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAP 531
               P     P + Q         P   +KP A      +PP Q   T  +   S++P P
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ--QTGSEKPSSEQPGP 388

Query: 532 ----PHPHLNKSQSLTNSLSTSDTSQRGTP 557
                 P + K+ +     +   T Q GTP
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 42/191 (21%), Positives = 65/191 (34%), Gaps = 26/191 (13%)

Query: 375  GEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPG--QAQLGPQLGQP 432
            G   E   Q   D V  K  + P    T  SP     P  K + +P   +   G  +  P
Sbjct: 835  GPSSESKGQKQVDPVQKK--EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892

Query: 433  QPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQ----------GQQPLSPQSG-------- 474
            Q  P PQ   R+        + +P  Q  +PQ          G    S  S         
Sbjct: 893  QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952

Query: 475  SPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRP----PVQGRSTSQQGEESKKPA 530
             P  Q  PG+P     +    P     P +T  + P P    PV+  + +   E+ +  A
Sbjct: 953  GPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012

Query: 531  PPHPHLNKSQS 541
               P + ++++
Sbjct: 1013 EQAPTVKRTET 1023



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 45/177 (25%), Positives = 65/177 (36%), Gaps = 22/177 (12%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ 451
           K+   P+   +A S   P   Q    K     Q   +  +P+ +PPP          QP 
Sbjct: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK-KPPP-------LVKQPT 711

Query: 452 RSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQAS--KPGATLASQ 509
             GSPS +   P     LS    +P ++ S  S Q     +   P Q    KP   L S 
Sbjct: 712 LHGSPSAKAKQPPEADSLS--KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769

Query: 510 ----PRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEA 562
                +P +       Q EE  K  PP     K+ S   S S   T ++ +P + +A
Sbjct: 770 SSATTKPDIPSSKVQSQAEE--KTTPP----LKTDSAKPSQSFPPTGEKVSPFDSKA 820



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 35/174 (20%), Positives = 62/174 (35%), Gaps = 19/174 (10%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPR------Q 444
           S  ++ P    +   P  P  P +     P +    P +   +P+ P    P        
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSV-----PSEQDKAP-VADDKPKQPKMVKPTTDLVSSS 770

Query: 445 AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGA 504
           + + +P    S  Q +   +   PL   S  P Q   P   ++S   S + P  AS   +
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS--DS 828

Query: 505 TLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
            + S P P  + +   Q     KK  P      K+Q+  +    +    +G+P+
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEP-----KKAQTKMSPKPDAKPMPKGSPT 877



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 40/194 (20%), Positives = 77/194 (39%), Gaps = 21/194 (10%)

Query: 367  MDSSMPLIG-EHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQL 425
            M+   P++  +  +E+ +L  D   +   + P+P       L P   +I+S +       
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLP---EEKKLIPEEEKIRSEEKK----- 1233

Query: 426  GPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP---SQQRLSPQGQQ----PLSPQSGSPQQ 478
             P L + +P P  +    +A++  P+        SQ +++ +  +    P + Q G   Q
Sbjct: 1234 -PLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ 1292

Query: 479  QRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTS-QQGEESKKPAPPHPHLN 537
             +  G P     +  S P +  K   T+  QP+PP   +    + G+E  +        +
Sbjct: 1293 TKMEGLPS---GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349

Query: 538  KSQSLTNSLSTSDT 551
             SQ   +    SDT
Sbjct: 1350 SSQQPKSPQGLSDT 1363



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 30/190 (15%)

Query: 394  SQLPMPGGTAPS-PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
            SQLP    +  S P +P  P  +S+     AQ  P    P P PPP   P     P P  
Sbjct: 2374 SQLPSGSPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT- 2431

Query: 453  SGSPSQQRLSPQGQQPLSPQS------------GSPQQQRSPGSPQLSRASSGSSPNQAS 500
              SP    L  +     SP +             +    RS G P ++R  + + P    
Sbjct: 2432 --SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLP-VTRICTTAPPPVPP 2488

Query: 501  KP-----GATLASQP---RPPVQGRST-SQQGEESKKPAPPHPH---LNKSQSLTNSLST 548
            KP     G     +P   +PP+  +    Q    ++KP   HP    L+ + S+T +L T
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548

Query: 549  SDTSQRGTPS 558
            S   +  +P+
Sbjct: 2549 SADYKLPSPT 2558


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 45/144 (31%), Positives = 62/144 (43%), Gaps = 15/144 (10%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRP---PPQGGPRQAQSPQPQRSGS 455
           P GT   P +P  P    A+  G  +  P   QP P+    PP  G   AQ P P +   
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEK--PSSEQPGPKALAQPPGVGKTPAQQPGPAKP-- 410

Query: 456 PSQQRLSPQGQQPLSPQSG--SPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQ---P 510
           P+QQ  +P+   PL+ Q G  SP +   P    + +   G  P Q + PG T A Q    
Sbjct: 411 PTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467

Query: 511 RPPVQGRSTSQQGEESKKPAPPHP 534
           +PP Q    ++   +   PA P P
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPP 491



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 16/141 (11%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG 454
           Q P PG     P +   P   SA+  G  +   QL  P   PP Q GP +   P PQ+ G
Sbjct: 442 QQPGPGKI---PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK---PPPQQPG 495

Query: 455 SPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQ---ASKPGATLASQPR 511
           S       P  QQP S +   P QQ  P  P   +  S   P+Q   ++KP A   S  +
Sbjct: 496 SAK-----PPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548

Query: 512 PPVQGRSTSQQGEESKKPAPP 532
           P  Q  +       S KP  P
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQP 569



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 12/180 (6%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQR--L 461
           P PL         AK+PG  +   Q   P   P  Q GP +  + Q   +  PSQ     
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477

Query: 462 SPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQ 521
            P  QQP  P    PQQ   PGS +      GS+     +PG    S P+ P   +  SQ
Sbjct: 478 KPPPQQP-GPAKPPPQQ---PGSAKPPSQQPGSTKPPPQQPGPAKPS-PQQPGSTKPPSQ 532

Query: 522 QGEESK----KPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKSFASL 577
           Q   +K    +P+P  P   +S    +   +    Q  T S   AK    + L K+   L
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-PSAKQPPSQGLPKTICPL 591



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 41/131 (31%), Positives = 53/131 (40%), Gaps = 16/131 (12%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQ 458
           PG T+     P  P    ++ PG A+  PQ   P   PP Q G  +  S QP  +  P Q
Sbjct: 456 PGKTSAQQTGPTKPP---SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 459 QR--LSPQGQQPLSPQSGSPQ--------QQRSPGSPQLSRASSGSSPNQASK---PGAT 505
           Q     P  QQP S +  S Q        QQ SP  P   +++   S   + K   P   
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572

Query: 506 LASQPRPPVQG 516
             S  +PP QG
Sbjct: 573 SPSAKQPPSQG 583



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 51/183 (27%), Positives = 72/183 (39%), Gaps = 27/183 (14%)

Query: 393 MSQLPMPGGTA---PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSP- 448
           ++Q P  G T    P P +P   Q+ + K   Q    P L  P   P P   P Q   P 
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ---PGLQSPAKAPGPTKTPVQQPGPG 447

Query: 449 ----QPQRSGSPSQQRLSP-QGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPG 503
               Q    G  S Q+  P +    L   +  P QQ  P  P   +  S   P+Q  +PG
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ--QPG 505

Query: 504 ATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAK 563
           +T     +PP Q     Q G    KP+P  P   K  S     S   ++Q+ +P++  A+
Sbjct: 506 ST-----KPPPQ-----QPG--PAKPSPQQPGSTKPPSQQPG-SAKPSAQQPSPAKPSAQ 552

Query: 564 AET 566
             T
Sbjct: 553 QST 555



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 52/170 (30%), Positives = 68/170 (40%), Gaps = 37/170 (21%)

Query: 399 PGGTAPSPLRPWAPQ-IKSAKSPGQAQLGPQLGQP------QP-----RPPPQGGPRQA- 445
           P G    PL+   P+ I   + PG+  L  Q G P      QP     +PP  G P Q  
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPL-QQDGTPKSISSQQPEKIKSQPPGTGKPIQGP 261

Query: 446 -QSPQPQRSGSPSQQRLS-PQGQQP-----------LSPQSGSPQQQRSPGSPQLSRASS 492
            Q+PQ   +  P Q+  S PQ +Q            L   S  P QQ +PG P   +   
Sbjct: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH 321

Query: 493 GSSPNQASKPGAT-------LASQP---RPPVQGRSTSQQGEESKKPAPP 532
             S    +KP A        LA QP   +PPVQ   T++   +   PA P
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP 371



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 8/151 (5%)

Query: 400 GGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQ 459
           G  AP P  P  P++K+A     + +     QPQ     Q  P++  +P+   S +P  +
Sbjct: 648 GDLAPVPSSP-QPKLKTAPVTTTSAVSKSSPQPQ-----QTSPKKDAAPKQDLSKAPEPK 701

Query: 460 RLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASK--PGATLASQPRPPVQGR 517
           +  P  +QP    S S + ++ P +  LS+ +    P+  S+         +P+ P   +
Sbjct: 702 KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761

Query: 518 STSQQGEESKKPAPPHPHLNKSQSLTNSLST 548
            T+     S     P    +K QS     +T
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 40/148 (27%), Positives = 59/148 (39%), Gaps = 21/148 (14%)

Query: 401 GTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGS--PSQ 458
           G A  P +P       A+ PG  +  P +  P    PP   P     P  Q++GS  PS 
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVK--PPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSS 383

Query: 459 QRLSPQGQQPLSPQSGSPQQQRSPGSP---------QLSRASSGSSPNQASKPGATLASQ 509
           ++  P+          +P QQ  P  P          L++     SP +A  P  T   Q
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443

Query: 510 PRP---PVQ----GRSTSQQGEESKKPA 530
           P P   P Q    G++++QQ   +K P+
Sbjct: 444 PGPGKIPAQQAGPGKTSAQQTGPTKPPS 471



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 38/150 (25%), Positives = 53/150 (35%), Gaps = 16/150 (10%)

Query: 412 PQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSP 471
           PQ K A       + P L  P P  PP       Q P P +   P+QQ    + Q   + 
Sbjct: 281 PQTKQADIVRGESVKPSL--PSPSKPP------IQQPTPGK--PPAQQPGHEKSQPGPAK 330

Query: 472 QSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAP 531
               P     P + Q         P   +KP A      +PP Q   T  +   S++P P
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ--QTGSEKPSSEQPGP 388

Query: 532 ----PHPHLNKSQSLTNSLSTSDTSQRGTP 557
                 P + K+ +     +   T Q GTP
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 42/191 (21%), Positives = 65/191 (34%), Gaps = 26/191 (13%)

Query: 375  GEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPG--QAQLGPQLGQP 432
            G   E   Q   D V  K  + P    T  SP     P  K + +P   +   G  +  P
Sbjct: 835  GPSSESKGQKQVDPVQKK--EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892

Query: 433  QPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQ----------GQQPLSPQSG-------- 474
            Q  P PQ   R+        + +P  Q  +PQ          G    S  S         
Sbjct: 893  QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952

Query: 475  SPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRP----PVQGRSTSQQGEESKKPA 530
             P  Q  PG+P     +    P     P +T  + P P    PV+  + +   E+ +  A
Sbjct: 953  GPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012

Query: 531  PPHPHLNKSQS 541
               P + ++++
Sbjct: 1013 EQAPTVKRTET 1023



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 45/177 (25%), Positives = 65/177 (36%), Gaps = 22/177 (12%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ 451
           K+   P+   +A S   P   Q    K     Q   +  +P+ +PPP          QP 
Sbjct: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK-KPPP-------LVKQPT 711

Query: 452 RSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQAS--KPGATLASQ 509
             GSPS +   P     LS    +P ++ S  S Q     +   P Q    KP   L S 
Sbjct: 712 LHGSPSAKAKQPPEADSLS--KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769

Query: 510 ----PRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEA 562
                +P +       Q EE  K  PP     K+ S   S S   T ++ +P + +A
Sbjct: 770 SSATTKPDIPSSKVQSQAEE--KTTPP----LKTDSAKPSQSFPPTGEKVSPFDSKA 820



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 35/174 (20%), Positives = 62/174 (35%), Gaps = 19/174 (10%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPR------Q 444
           S  ++ P    +   P  P  P +     P +    P +   +P+ P    P        
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSV-----PSEQDKAP-VADDKPKQPKMVKPTTDLVSSS 770

Query: 445 AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGA 504
           + + +P    S  Q +   +   PL   S  P Q   P   ++S   S + P  AS   +
Sbjct: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS--DS 828

Query: 505 TLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
            + S P P  + +   Q     KK  P      K+Q+  +    +    +G+P+
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEP-----KKAQTKMSPKPDAKPMPKGSPT 877



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 40/194 (20%), Positives = 77/194 (39%), Gaps = 21/194 (10%)

Query: 367  MDSSMPLIG-EHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQL 425
            M+   P++  +  +E+ +L  D   +   + P+P       L P   +I+S +       
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLP---EEKKLIPEEEKIRSEEKK----- 1233

Query: 426  GPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP---SQQRLSPQGQQ----PLSPQSGSPQQ 478
             P L + +P P  +    +A++  P+        SQ +++ +  +    P + Q G   Q
Sbjct: 1234 -PLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ 1292

Query: 479  QRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTS-QQGEESKKPAPPHPHLN 537
             +  G P     +  S P +  K   T+  QP+PP   +    + G+E  +        +
Sbjct: 1293 TKMEGLPS---GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349

Query: 538  KSQSLTNSLSTSDT 551
             SQ   +    SDT
Sbjct: 1350 SSQQPKSPQGLSDT 1363



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 30/190 (15%)

Query: 394  SQLPMPGGTAPS-PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
            SQLP    +  S P +P  P  +S+     AQ  P    P P PPP   P     P P  
Sbjct: 2374 SQLPSGSPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT- 2431

Query: 453  SGSPSQQRLSPQGQQPLSPQS------------GSPQQQRSPGSPQLSRASSGSSPNQAS 500
              SP    L  +     SP +             +    RS G P ++R  + + P    
Sbjct: 2432 --SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLP-VTRICTTAPPPVPP 2488

Query: 501  KP-----GATLASQP---RPPVQGRST-SQQGEESKKPAPPHPH---LNKSQSLTNSLST 548
            KP     G     +P   +PP+  +    Q    ++KP   HP    L+ + S+T +L T
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548

Query: 549  SDTSQRGTPS 558
            S   +  +P+
Sbjct: 2549 SADYKLPSPT 2558


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 46/146 (31%), Positives = 55/146 (37%), Gaps = 15/146 (10%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQP-RPPPQGGPRQAQSPQPQRSGS 455
           P PG + P P  P  P  +  + P   Q  PQ  QP P +PPP   P Q Q P P     
Sbjct: 49  PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQ--QPPPHQPPPHPQPHQQQQPPP----- 101

Query: 456 PSQQRLSP---QGQQPLSPQSGSPQQQRS--PGSPQLSRASSGSSPNQASKPGATLASQP 510
           P Q    P   QG  P      +P    S  P +P  S A  GS P     P   + S P
Sbjct: 102 PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161

Query: 511 --RPPVQGRSTSQQGEESKKPAPPHP 534
              PP    S+       +   PP P
Sbjct: 162 PGAPPPTPPSSGVPTTPPQAGGPPPP 187



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 42/125 (33%), Positives = 52/125 (41%), Gaps = 17/125 (13%)

Query: 413 QIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQ 472
           Q +    PG  Q GP+   P P PPP    +Q Q P PQ+   P QQ   P  Q P  PQ
Sbjct: 42  QNRGPMGPGPGQSGPK--PPIPPPPPH---QQQQQPPPQQ--PPPQQ--PPPHQPPPHPQ 92

Query: 473 SGSPQQQRSPGSPQLS-----RASSGSSPNQASKPGATLASQP-RPPVQGRSTSQQGEES 526
               QQQ+ P  PQ S         G +P   S P A+ ++ P  PP  G         +
Sbjct: 93  --PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT 150

Query: 527 KKPAP 531
             P P
Sbjct: 151 PTPPP 155



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/140 (27%), Positives = 49/140 (35%), Gaps = 28/140 (20%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPR---QAQSPQPQRSGS 455
           P G+ P P     P + SA            G P P PP  G P    QA  P P  +  
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPP----------GAPPPTPPSSGVPTTPPQAGGPPPPPAAV 191

Query: 456 PSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQ 515
           P       QG  P  P+ G     + PG P+      G  P   S PG      P+PP +
Sbjct: 192 PGPGPGPKQGPGPGGPKGG-----KMPGGPK-----PGGGPG-LSTPG----GHPKPPHR 236

Query: 516 GRSTSQQGEESKKPAPPHPH 535
           G    + G +   P     H
Sbjct: 237 GGGEPRGGRQHHPPYHQQHH 256



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 47/160 (29%), Positives = 57/160 (35%), Gaps = 29/160 (18%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPR----QAQSPQP 450
           Q   P    P P +P   Q      P Q        Q QP PPPQ   +    Q   P P
Sbjct: 68  QQQQPPPQQPPPQQPPPHQPPPHPQPHQ--------QQQPPPPPQDSSKPVVAQGPGPAP 119

Query: 451 QRSGSPSQQRLSPQGQQPLS---PQSG------SPQQQRS--PGSPQLSRASSG--SSPN 497
               +P     +P    P S   P SG       P    S  PG+P  +  SSG  ++P 
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP 179

Query: 498 QASKPGATLASQPRP---PVQGRSTSQQGEESKKPAPPHP 534
           QA  P    A+ P P   P QG       +  K P  P P
Sbjct: 180 QAGGPPPPPAAVPGPGPGPKQGPGPGGP-KGGKMPGGPKP 218


>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
          Length = 845

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 53/185 (28%), Positives = 67/185 (36%), Gaps = 33/185 (17%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQL----GQPQPRPPP-----------QGG 441
           P  GGT      PW         P +   GP      G   P PP             GG
Sbjct: 465 PEAGGTTG----PWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGG 520

Query: 442 PRQAQ---SPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQ 498
           P  A+   S QP   G  + Q   P   QP+ P  G+    + P +P     S G++  Q
Sbjct: 521 PPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQ-PATP-----SGGTA--Q 572

Query: 499 ASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
             +PG    SQP PP  G STS Q           P    SQ +   + TS + Q  TP 
Sbjct: 573 TPEPGT---SQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPG 629

Query: 559 EDEAK 563
              A+
Sbjct: 630 GGTAQ 634



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 53/192 (27%), Positives = 68/192 (35%), Gaps = 58/192 (30%)

Query: 400 GGTAPSP-----LRP-------WAPQIKSAKSPGQAQLG------PQLGQPQPRPP---- 437
           GGT P P     LRP         P  +++ S   A  G      P+ G  QP PP    
Sbjct: 498 GGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGT 557

Query: 438 --------PQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSR 489
                   P GG   AQ+P+P  S        +    QP +P  G+ Q   +  S  +  
Sbjct: 558 STSHQPATPSGGT--AQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPP 615

Query: 490 ASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTS 549
               S+ +Q + PG   A  P P      TSQ       P P              LS S
Sbjct: 616 GMGTSTSHQPTTPGGGTAQTPEP-----GTSQ-------PMP--------------LSKS 649

Query: 550 DTSQRGTPSEDE 561
             S  G PSED+
Sbjct: 650 TPSSGGGPSEDK 661


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 50/183 (27%), Positives = 77/183 (42%), Gaps = 28/183 (15%)

Query: 409 PWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQP 468
           P  P  +  +SP  A   P   +  P PPP+   R+  SP P+R  SPS +R SP  Q+ 
Sbjct: 550 PSPPPTRRRRSPSPAP--PPRRRRTPTPPPR---RRTPSPPPRRR-SPSPRRYSPPIQRR 603

Query: 469 LSPQ----------SGSPQQQRSPGSPQLSRASSGSSPNQASKP-----GATLASQPRPP 513
            SP              P+++ SP  P   R S    P Q S P       +L+S+ R  
Sbjct: 604 YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHR-- 661

Query: 514 VQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQR----GTPSEDEAKAETIRN 569
            +G S S+   E++ P P   H    +      S+S    R     +P   ++ + + R 
Sbjct: 662 -KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720

Query: 570 LRK 572
           +R+
Sbjct: 721 IRR 723



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 11/150 (7%)

Query: 403 APSPLR--PWAPQIKSAKSPGQAQLGPQLGQPQPR-PPPQGGPRQAQSPQPQRSGSPSQQ 459
           +P P R    +P  K   SP   +  P L     +   P    R+A+SPQP +  SPS +
Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR 687

Query: 460 RLSPQGQQPLSP----QSGSPQQQRSPG--SPQLSRASSGSSPNQASKPGATLASQPRPP 513
             +PQ      P     S SPQ+++SP   +  + R S    P +  K  +      R  
Sbjct: 688 PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRV 747

Query: 514 VQGRSTSQQGEESKK--PAPPHPHLNKSQS 541
              RS S   E + K  PAPP P  ++S S
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 22/171 (12%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKS----AKSPGQAQLGPQLGQPQPRPPPQGGPRQAQ- 446
           ++S  P P   +    +  +P + S      SP ++    +  QP  R  P   PR  Q 
Sbjct: 634 RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQT 693

Query: 447 --SPQPQRSGSPS--QQRLSPQ-GQQPLSPQSGSPQQQR-----SPGSPQLSRASSGSSP 496
             SP P R G+ S  Q+R SP    +P+   S +P+ ++     SP    + R SS  S 
Sbjct: 694 SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSV 753

Query: 497 NQASKPGATLASQPRPPVQGRSTSQQG------EESKKPAP-PHPHLNKSQ 540
           + + +P A     P  PVQ +S S         +++K P P P P  N  Q
Sbjct: 754 SGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQ 804



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/142 (30%), Positives = 62/142 (43%), Gaps = 16/142 (11%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQ-------AQLGPQLGQPQPRPPPQGGPRQAQSPQ 449
           P P   +PSP R ++P I+   SP         +   P   +  P PPP+   R + SP 
Sbjct: 584 PPPRRRSPSPRR-YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR--RVSHSPP 640

Query: 450 PQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQ 509
           P++  SP  +R SP         S   +  R   SPQ ++  S S      +P A   S 
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS-----PRPRAPQTSS 695

Query: 510 PRPPV-QGRSTSQQGEESKKPA 530
             PPV +G S+S Q  +S  P+
Sbjct: 696 SPPPVRRGASSSPQRRQSPSPS 717



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/156 (24%), Positives = 57/156 (36%), Gaps = 16/156 (10%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSP 463
           P P R         +SP   +  P + +     PP      +  P P+R  SPS      
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR 634

Query: 464 QGQQPLSPQSGSPQQQRSPGSPQL-SRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQ 522
               P   Q  SP  +R   SP L S+   GSSP+++++             + RS    
Sbjct: 635 VSHSPPPKQRSSPVTKRR--SPSLSSKHRKGSSPSRSTR-------------EARSPQPN 679

Query: 523 GEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
              S  P P  P  + S       ++S   +R +PS
Sbjct: 680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS 715



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 11/138 (7%)

Query: 408 RPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPS----QQRLSP 463
           R +  Q + + S   +    +  +P+      G   + +   P RS SPS    Q+  SP
Sbjct: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP 542

Query: 464 QGQQPLSPQSGSPQQQRSPG-SPQLSRASSGSSP---NQASKPGATLASQPR---PPVQG 516
           +G++  SP     +++RSP  +P   R  + + P      S P    +  PR   PP+Q 
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR 602

Query: 517 RSTSQQGEESKKPAPPHP 534
           R +     + +  +PP P
Sbjct: 603 RYSPSPPPKRRTASPPPP 620



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 432 PQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRAS 491
           P+ RP P+  P   +   P+R   P + R           +S SP ++R   S  LS +S
Sbjct: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHR-----------RSRSPVRRRRRSSASLSGSS 359

Query: 492 SGSSPNQA----SKPGATLASQPRPPVQGRSTSQQGEESKKPAPP 532
           S SS +++     KP    +S PR   +   ++       +P+PP
Sbjct: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 41/198 (20%), Positives = 68/198 (34%), Gaps = 29/198 (14%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSP------GQAQLG---PQLGQPQPRPPPQGGPRQAQS 447
           P P    P    P  P+ + ++SP        A L          + R PP+  P++  S
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380

Query: 448 PQ------------PQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSS 495
           P             P+R   PS     P    P +  S +PQQ       ++S +   +S
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPP----PKTRHSPTPQQSNRTRKSRVSVSPGRTS 436

Query: 496 PNQASKPGATLASQPRPPVQGR----STSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDT 551
                  G      P P  + R    S S++ +  K  A       +     N  S+SD+
Sbjct: 437 GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496

Query: 552 SQRGTPSEDEAKAETIRN 569
               +  ++  K   ++N
Sbjct: 497 GSSSSSEDERPKRSHVKN 514



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 32/126 (25%), Positives = 53/126 (42%), Gaps = 15/126 (11%)

Query: 443 RQAQSPQPQRSGSP-------SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSS 495
           R+++SP P+R  SP       S  R      +  SP     +++++P  P+ S      S
Sbjct: 175 RKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234

Query: 496 PNQASK-------PGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLST 548
             +A+        P      +P+ P      S++ +E +K  P     +KS+S T S S 
Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEP-SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSP 293

Query: 549 SDTSQR 554
           S T  R
Sbjct: 294 SHTRPR 299



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 38/186 (20%), Positives = 66/186 (35%), Gaps = 26/186 (13%)

Query: 403 APSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQP---------QRS 453
           +PSP R  +P  +  K         +     P P P+   +  + P+P         Q +
Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA 238

Query: 454 GSPSQQRLSPQGQQPLSPQSGSPQQQ-RSPGSPQLSRASSGSSPNQASKPGATLASQPRP 512
            S S     P+ +    P+  SP++  +     + +R  S S     S+  +   S  RP
Sbjct: 239 TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP 298

Query: 513 PVQGRSTSQQGEESKKPA----------------PPHPHLNKSQSLTNSLSTSDTSQRGT 556
             + RS S+     ++P+                PP P   +S+S       S  S  G+
Sbjct: 299 RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358

Query: 557 PSEDEA 562
            S   +
Sbjct: 359 SSSSSS 364



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 33/165 (20%), Positives = 64/165 (38%), Gaps = 23/165 (13%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 456
           P P  T P   R  +P  + +    ++++    G+   +     G  + +SP P  +  P
Sbjct: 401 PSPPATPPPKTRH-SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP--APKP 457

Query: 457 SQQRLSP----QGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKP---------- 502
            +  LS     +G +  +  S   ++Q    + Q S  S  SS ++  +P          
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV 517

Query: 503 ------GATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQS 541
                   + ++ P P  + + TS +G   + P+PP     +S S
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 47/170 (27%), Positives = 64/170 (37%), Gaps = 23/170 (13%)

Query: 393 MSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
           +SQ  +PG   P+PL    PQ      P   Q         P PPP              
Sbjct: 781 VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQ-----SPLHPTPPPAS----------TA 825

Query: 453 SGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRP 512
           +G PS Q  +P G  P  PQ  +P Q  +P    +S +    +P   S P AT  +Q  P
Sbjct: 826 AGMPSLQHTTPPGMTP--PQPAAPTQPSTP----VSSSGQTPTPTPGSVPSAT-QTQSTP 878

Query: 513 PVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEA 562
            VQ  + +Q   + + P  P P +   QS     +       GTP    A
Sbjct: 879 TVQAAAQAQVTPQPQTPVQP-PSVATPQSSQQQPTPVHAQPPGTPLSQAA 927



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 48/217 (22%)

Query: 394  SQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQ--LGPQLGQPQPRPPPQGGP---RQAQSP 448
            SQLP P  T  SPL P  P   +A      Q    P +  PQP  P Q         Q+P
Sbjct: 803  SQLPCPPVTQ-SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 861

Query: 449  QPQRSGSPS--------------QQRLSPQGQQPLSP----------QSGSPQQQRSPGS 484
             P     PS              Q +++PQ Q P+ P          Q  +P   + PG+
Sbjct: 862  TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGT 921

Query: 485  PQLSRASSGSSPNQASKPGA-----TLASQPRP--PVQGRSTSQQGEESKKPAPPHPHLN 537
            P LS+A++ S  N+   P +     T + QP P  PV    T  Q E+++          
Sbjct: 922  P-LSQAAA-SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEP 979

Query: 538  KSQSLTNSL--------STSDTSQRGTPSE-DEAKAE 565
            +S+ +   L         T    Q+  P E DE K E
Sbjct: 980  RSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPE 1016



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 42/192 (21%), Positives = 74/192 (38%), Gaps = 21/192 (10%)

Query: 351  VKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPG-----GTAPS 405
            +K+  S   +  ++ ++ S+  L+   +   +Q  A  V ++    P PG     G  P 
Sbjct: 2036 LKSPSSPQQQQQVLNILKSNPQLMAAFI---KQRTAKYVANQPGMQPQPGLQSQPGMQPQ 2092

Query: 406  PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG------SPSQQ 459
            P     P +++  +        Q G P+P  PPQ       +PQ Q         +P+  
Sbjct: 2093 PGMHQQPSLQNLNAM-------QAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMA 2145

Query: 460  RLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRST 519
             ++PQ ++ L  Q    QQQ+     Q  +   GS+       G     QP+ P      
Sbjct: 2146 SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPA 2205

Query: 520  SQQGEESKKPAP 531
             QQ +  ++  P
Sbjct: 2206 MQQQQRMQQHLP 2217



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/172 (26%), Positives = 68/172 (39%), Gaps = 28/172 (16%)

Query: 383  QLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQ-------LGPQL------ 429
            Q  A +   +M  +  P   +PS L+     +KS  SP Q Q         PQL      
Sbjct: 2005 QAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIK 2064

Query: 430  --------GQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRS 481
                     QP  +P P    +    PQP     PS Q L+    Q   P+ G P QQ++
Sbjct: 2065 QRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLN--AMQAGVPRPGVPPQQQA 2122

Query: 482  PG--SPQ---LSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKK 528
             G  +PQ   L+  + G +PN AS          R  +Q +   QQ ++ ++
Sbjct: 2123 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQ 2174



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 4/122 (3%)

Query: 442  PRQA-QSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQAS 500
            P+Q+  SP     G+P+QQ  +PQ  QP +    SP      G P ++R    ++ +   
Sbjct: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS-TG 1898

Query: 501  KPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSED 560
            KP + + + P P     +  +   + ++ A    HL +  ++ NS+    T   GTP   
Sbjct: 1899 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYR-VNINNSMPPGRTGM-GTPGSQ 1956

Query: 561  EA 562
             A
Sbjct: 1957 MA 1958



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 18/174 (10%)

Query: 399  PGGTAPSPLRPWAPQIK-SAKSPGQAQLGPQLGQ-PQPRPPPQGGPRQAQSPQPQRSGSP 456
            PGG  P+  +    Q     +     Q+  Q+GQ  Q   P  G        Q  +    
Sbjct: 2199 PGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRIL 2258

Query: 457  SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLS----RASSGSSPNQASKPGATLASQPRP 512
             QQ++  Q   P  P   SPQQ    G PQ S    +  + S  NQ   P       PRP
Sbjct: 2259 QQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAP--VQSPRP 2316

Query: 513  PVQGRSTSQQGEESKKPAPPH-------PHLNKSQSLTNSLSTSDTSQRGTPSE 559
              Q   +S       +P+P H       PH   + ++ +S+   D    G P +
Sbjct: 2317 QSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSI---DQGHLGNPEQ 2367



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 40/187 (21%), Positives = 65/187 (34%), Gaps = 12/187 (6%)

Query: 397  PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQ-PQPRPPPQGGPRQAQSPQPQRSGS 455
            P P   + SP     P +   + P     G    Q P P PP Q  P   ++ +     +
Sbjct: 1871 PQPSPVSMSPAG--FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1928

Query: 456  PSQQRLSP----QGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPR 511
              QQ L          P     G+P  Q +P S  + R +  S P   S P       P 
Sbjct: 1929 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPL 1988

Query: 512  P---PVQG--RSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAET 566
            P   P+ G  R       ++    P  P +   +S++ S          +PS  + + + 
Sbjct: 1989 PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQV 2048

Query: 567  IRNLRKS 573
            +  L+ +
Sbjct: 2049 LNILKSN 2055



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 11/64 (17%)

Query: 427  PQLGQPQPRPPPQGGPRQA----QSPQPQRSGSPSQQRLSPQG-------QQPLSPQSGS 475
            PQ   P P   P G P Q     Q+PQP     PS   +SP G       Q P +  +G 
Sbjct: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1899

Query: 476  PQQQ 479
            P  Q
Sbjct: 1900 PTSQ 1903



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 40/141 (28%), Positives = 53/141 (37%), Gaps = 38/141 (26%)

Query: 367  MDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLG 426
            M   +PL G  + +    M  L      Q+  PG  A S   P   Q    +   Q Q+ 
Sbjct: 2212 MQQHLPLQGSSMGQMAAQMGQL-----GQMGQPGLGADST--PNIQQALQQRILQQQQMK 2264

Query: 427  PQLG---QPQPRPPPQ----GGPR---------------QAQSPQPQRSGSPSQQ----- 459
             Q+G   QP P  P Q    G P+               Q +SP P +S  P  Q     
Sbjct: 2265 QQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSS 2324

Query: 460  ---RLSPQ-GQQPLSPQSGSP 476
               R+ PQ     +SPQ+GSP
Sbjct: 2325 PSPRIQPQPSPHHVSPQTGSP 2345



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 36/123 (29%), Positives = 45/123 (36%), Gaps = 17/123 (13%)

Query: 438 PQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQL-SRASSGSSP 496
           P  G   A SP  Q  G  +Q + +      LS    SP  Q    +P L  +A+S S P
Sbjct: 84  PGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGP 143

Query: 497 NQASKPGATLASQPRPPVQ-GRSTSQQGEESKKPA--------PPHPHL---NKSQSLTN 544
                P A+ A  P+   Q G +TS        P           HP L   N   SL N
Sbjct: 144 T----PAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLIN 199

Query: 545 SLS 547
             S
Sbjct: 200 QAS 202



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 12/81 (14%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLG-PQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLS 462
           P+P+ P      S+     A LG P + QPQ +  PQ   +Q   PQ  +      + L+
Sbjct: 435 PNPIDP------SSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQ----QMRTLN 484

Query: 463 PQGQQPLS-PQSGSPQQQRSP 482
           P G  P++ P  G    Q+ P
Sbjct: 485 PLGNNPMNIPAGGITTDQQPP 505


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 47/170 (27%), Positives = 64/170 (37%), Gaps = 23/170 (13%)

Query: 393 MSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
           +SQ  +PG   P+PL    PQ      P   Q         P PPP              
Sbjct: 819 VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQ-----SPLHPTPPPAS----------TA 863

Query: 453 SGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRP 512
           +G PS Q  +P G  P  PQ  +P Q  +P    +S +    +P   S P AT  +Q  P
Sbjct: 864 AGMPSLQHTTPPGMTP--PQPAAPTQPSTP----VSSSGQTPTPTPGSVPSAT-QTQSTP 916

Query: 513 PVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEA 562
            VQ  + +Q   + + P  P P +   QS     +       GTP    A
Sbjct: 917 TVQAAAQAQVTPQPQTPVQP-PSVATPQSSQQQPTPVHAQPPGTPLSQAA 965



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 48/217 (22%)

Query: 394  SQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQ--LGPQLGQPQPRPPPQGGP---RQAQSP 448
            SQLP P  T  SPL P  P   +A      Q    P +  PQP  P Q         Q+P
Sbjct: 841  SQLPCPPVTQ-SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 899

Query: 449  QPQRSGSPS--------------QQRLSPQGQQPLSP----------QSGSPQQQRSPGS 484
             P     PS              Q +++PQ Q P+ P          Q  +P   + PG+
Sbjct: 900  TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGT 959

Query: 485  PQLSRASSGSSPNQASKPGA-----TLASQPRP--PVQGRSTSQQGEESKKPAPPHPHLN 537
            P LS+A++ S  N+   P +     T + QP P  PV    T  Q E+++          
Sbjct: 960  P-LSQAAA-SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEP 1017

Query: 538  KSQSLTNSL--------STSDTSQRGTPSE-DEAKAE 565
            +S+ +   L         T    Q+  P E DE K E
Sbjct: 1018 RSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPE 1054



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 42/192 (21%), Positives = 74/192 (38%), Gaps = 21/192 (10%)

Query: 351  VKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPG-----GTAPS 405
            +K+  S   +  ++ ++ S+  L+   +   +Q  A  V ++    P PG     G  P 
Sbjct: 2074 LKSPSSPQQQQQVLNILKSNPQLMAAFI---KQRTAKYVANQPGMQPQPGLQSQPGMQPQ 2130

Query: 406  PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG------SPSQQ 459
            P     P +++  +        Q G P+P  PPQ       +PQ Q         +P+  
Sbjct: 2131 PGMHQQPSLQNLNAM-------QAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMA 2183

Query: 460  RLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRST 519
             ++PQ ++ L  Q    QQQ+     Q  +   GS+       G     QP+ P      
Sbjct: 2184 SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPA 2243

Query: 520  SQQGEESKKPAP 531
             QQ +  ++  P
Sbjct: 2244 MQQQQRMQQHLP 2255



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/172 (26%), Positives = 68/172 (39%), Gaps = 28/172 (16%)

Query: 383  QLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQ-------LGPQL------ 429
            Q  A +   +M  +  P   +PS L+     +KS  SP Q Q         PQL      
Sbjct: 2043 QAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIK 2102

Query: 430  --------GQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRS 481
                     QP  +P P    +    PQP     PS Q L+    Q   P+ G P QQ++
Sbjct: 2103 QRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLN--AMQAGVPRPGVPPQQQA 2160

Query: 482  PG--SPQ---LSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKK 528
             G  +PQ   L+  + G +PN AS          R  +Q +   QQ ++ ++
Sbjct: 2161 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQ 2212



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 4/122 (3%)

Query: 442  PRQA-QSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQAS 500
            P+Q+  SP     G+P+QQ  +PQ  QP +    SP      G P ++R    ++ +   
Sbjct: 1878 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS-TG 1936

Query: 501  KPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSED 560
            KP + + + P P     +  +   + ++ A    HL +  ++ NS+    T   GTP   
Sbjct: 1937 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYR-VNINNSMPPGRTGM-GTPGSQ 1994

Query: 561  EA 562
             A
Sbjct: 1995 MA 1996



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 18/174 (10%)

Query: 399  PGGTAPSPLRPWAPQIK-SAKSPGQAQLGPQLGQ-PQPRPPPQGGPRQAQSPQPQRSGSP 456
            PGG  P+  +    Q     +     Q+  Q+GQ  Q   P  G        Q  +    
Sbjct: 2237 PGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRIL 2296

Query: 457  SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLS----RASSGSSPNQASKPGATLASQPRP 512
             QQ++  Q   P  P   SPQQ    G PQ S    +  + S  NQ   P       PRP
Sbjct: 2297 QQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAP--VQSPRP 2354

Query: 513  PVQGRSTSQQGEESKKPAPPH-------PHLNKSQSLTNSLSTSDTSQRGTPSE 559
              Q   +S       +P+P H       PH   + ++ +S+   D    G P +
Sbjct: 2355 QSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSI---DQGHLGNPEQ 2405



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 40/187 (21%), Positives = 65/187 (34%), Gaps = 12/187 (6%)

Query: 397  PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQ-PQPRPPPQGGPRQAQSPQPQRSGS 455
            P P   + SP     P +   + P     G    Q P P PP Q  P   ++ +     +
Sbjct: 1909 PQPSPVSMSPAG--FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1966

Query: 456  PSQQRLSP----QGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPR 511
              QQ L          P     G+P  Q +P S  + R +  S P   S P       P 
Sbjct: 1967 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPL 2026

Query: 512  P---PVQG--RSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAET 566
            P   P+ G  R       ++    P  P +   +S++ S          +PS  + + + 
Sbjct: 2027 PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQV 2086

Query: 567  IRNLRKS 573
            +  L+ +
Sbjct: 2087 LNILKSN 2093



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 11/64 (17%)

Query: 427  PQLGQPQPRPPPQGGPRQA----QSPQPQRSGSPSQQRLSPQG-------QQPLSPQSGS 475
            PQ   P P   P G P Q     Q+PQP     PS   +SP G       Q P +  +G 
Sbjct: 1878 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1937

Query: 476  PQQQ 479
            P  Q
Sbjct: 1938 PTSQ 1941



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 40/141 (28%), Positives = 53/141 (37%), Gaps = 38/141 (26%)

Query: 367  MDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLG 426
            M   +PL G  + +    M  L      Q+  PG  A S   P   Q    +   Q Q+ 
Sbjct: 2250 MQQHLPLQGSSMGQMAAQMGQL-----GQMGQPGLGADST--PNIQQALQQRILQQQQMK 2302

Query: 427  PQLG---QPQPRPPPQ----GGPR---------------QAQSPQPQRSGSPSQQ----- 459
             Q+G   QP P  P Q    G P+               Q +SP P +S  P  Q     
Sbjct: 2303 QQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSS 2362

Query: 460  ---RLSPQ-GQQPLSPQSGSP 476
               R+ PQ     +SPQ+GSP
Sbjct: 2363 PSPRIQPQPSPHHVSPQTGSP 2383



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 36/123 (29%), Positives = 45/123 (36%), Gaps = 17/123 (13%)

Query: 438 PQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQL-SRASSGSSP 496
           P  G   A SP  Q  G  +Q + +      LS    SP  Q    +P L  +A+S S P
Sbjct: 84  PGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGP 143

Query: 497 NQASKPGATLASQPRPPVQ-GRSTSQQGEESKKPA--------PPHPHL---NKSQSLTN 544
                P A+ A  P+   Q G +TS        P           HP L   N   SL N
Sbjct: 144 T----PAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLIN 199

Query: 545 SLS 547
             S
Sbjct: 200 QAS 202



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 12/81 (14%)

Query: 404 PSPLRPWAPQIKSAKSPGQAQLG-PQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLS 462
           P+P+ P      S+     A LG P + QPQ +  PQ   +Q   PQ  +      + L+
Sbjct: 473 PNPIDP------SSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQ----QMRTLN 522

Query: 463 PQGQQPLS-PQSGSPQQQRSP 482
           P G  P++ P  G    Q+ P
Sbjct: 523 PLGNNPMNIPAGGITTDQQPP 543


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 48/171 (28%), Positives = 66/171 (38%), Gaps = 14/171 (8%)

Query: 397 PMPGGTAPSPLRP---WAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRS 453
           PM     P P  P    AP ++   SP  +     L +P P+ PP       Q+     +
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 454 GSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPP 513
             P Q   SP    P+SP +  P Q      P L+       P+  + P  TL +  RPP
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQ----APPVLAAPLLQVPPSPPASP--TLQAPRRPP 859

Query: 514 VQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSD-----TSQRGTPSE 559
             G  TS  G        P P    S+S +++LS  D     +S   TP E
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 8/141 (5%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQP--QPRPPPQGGPRQAQSPQ--PQR 452
           P P    PSPL    P+  S+ +    Q  P L  P  Q  P P   P     PQ  P  
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 453 SGSPSQQRLSPQGQQPLSP-QSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPR 511
           +  P Q   SP    PLSP  + SPQ   +P +  +    +  SP  +    A  +    
Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQ---APNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 512 PPVQGRSTSQQGEESKKPAPP 532
           PPV   +T          APP
Sbjct: 683 PPVSPSATPPSQAPPSLAAPP 703



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 40/179 (22%), Positives = 63/179 (35%), Gaps = 10/179 (5%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQ--PRPPPQGGPR-QAQSP 448
           K ++ P     +    R  +       SP  A+     G     PRP P   PR   + P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 449 QPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLAS 508
           +   S +       P       P +G   Q+  P S  LS  SS +  +  ++ G +   
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQR--PASRSLS--SSATPLSSPARSGPSARG 261

Query: 509 QPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAETI 567
            PR P        +G ++ +P    P    +      LS+S  +   TPS    KA  +
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSGTKARPV 317



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 20/157 (12%)

Query: 393 MSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
           +S L  P   AP  L    P +++  SP  +     L  P P+ P        Q+P    
Sbjct: 611 LSPLATPPPQAPPXLA--LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668

Query: 453 SGSPSQQRLSPQGQQPLSPQSGSPQQQ---------RSPGSPQLS--RASSGSSPNQASK 501
              P Q   SP    P+SP +  P Q          + P SP  S   + S + P QA  
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728

Query: 502 PGAT--LASQPRPPVQGRSTSQQGEESKKPAPPHPHL 536
           P A   L   P PP      S     S  P P  P L
Sbjct: 729 PLAAPPLQVPPSPP-----ASPPMSPSATPPPRVPPL 760



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/165 (25%), Positives = 55/165 (33%), Gaps = 8/165 (4%)

Query: 372 PLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQ 431
           PL     +    L   L+ +  S  P P   AP       P   SA  P QA   P L  
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLAA 701

Query: 432 P--QPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSR 489
           P  Q  P P   P  + S  P     P     +P  Q P SP +  P    +   P++  
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLA--APPLQVPPSPPASPPMSPSATPPPRVPP 759

Query: 490 ASSGSSPNQASKPGATLASQP--RPPVQGRSTSQQGEESKKPAPP 532
             +         P A+L   P  +PP Q             P+PP
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 9/145 (6%)

Query: 422 QAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRL----SPQGQQPLSPQSGSPQ 477
           +A+ G     P  R P    PR   SP+P    +P+  R+       G++PL+ ++G   
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 478 QQRSPGSPQLS---RASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHP 534
               P S   +   R++  SS N AS+P A+   +  PP +  S        +      P
Sbjct: 67  GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 535 HLNKSQSLTNSLSTSDTSQRGTPSE 559
                + L   +S  +T  RG  +E
Sbjct: 127 GPLGQKGL--RISAEETVARGKATE 149



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 48/177 (27%), Positives = 62/177 (35%), Gaps = 38/177 (21%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQG------GPRQ 444
           S  + LPM     P P  P        + P      P L  P+ RPP  G      GPR 
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR-RPPTPGPDTSVSGPRL 872

Query: 445 ----AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRS-------------PGSPQL 487
               A  P P  S SPS     P      S  + +P++ R              P   +L
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 932

Query: 488 SRA-----SSGSSPNQASKPGATLASQPRPPVQGRSTSQ--------QGEESKKPAP 531
           +       S G +P  A + GA  A  P PP  G  ++         +G ES  PAP
Sbjct: 933 AACHPAAWSRGPAPPLAFR-GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 397  PMPGGTAPSPLRPWAPQ-----------IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQA 445
            P+    AP    PW P            I   + P  A   P    P P P   GG   A
Sbjct: 947  PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 1006

Query: 446  QSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRA-----SSGSSPNQAS 500
             +     S SP Q RL   G+ PL     S  Q     +  L+ A      SG  P  A 
Sbjct: 1007 GAGAGASSRSPKQARL---GELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 1063

Query: 501  KPGAT 505
              G T
Sbjct: 1064 GGGVT 1068



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 55/208 (26%), Positives = 84/208 (40%), Gaps = 36/208 (17%)

Query: 408 RPWAPQIKSAKSP--GQAQLGPQL-GQPQ-PRPPPQGGPRQAQSPQPQRSGSPSQQR--- 460
           RP +  + S+ +P    A+ GP   G P+ P  P Q  P+  Q+ +P +   P +     
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 461 LSPQGQQPLSPQSGSPQQQRS---------------PGSPQLSRASSGSSPNQASKPG-A 504
           L P    PL+  S S  + R                P SP L+     + P+ ++ P   
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355

Query: 505 TLASQP-RPPVQG----RSTSQQGEESKKPAPP--HPHLNKSQSL---TNSLSTSD---T 551
           TL S P  PP Q      +   Q   S +  PP   PH   S SL    + L+ S    T
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415

Query: 552 SQRGTPSEDEAKAETIRNLRKSFASLFS 579
           +  G+P+     +    + R++ ASL S
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLTS 443



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 44/132 (33%), Positives = 50/132 (37%), Gaps = 26/132 (19%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRP---PPQGGPRQAQSPQPQRS 453
           P+P    PSP  P A  +  A  P      P L Q  P P   PP   P    +P  Q  
Sbjct: 326 PLPATLPPSP--PLATPLPLA--PPSPSAPPSL-QTLPSPPATPPSQAPPSMTTPPMQ-- 378

Query: 454 GSPSQQRL----------SPQGQQPLSPQS-GSPQQQRSPGSPQLSRASS--GSSPNQAS 500
             PS Q +          SP  Q P SP +  S Q   S GSP L    S    SP Q  
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438

Query: 501 KPGATLASQPRP 512
              A+L S  RP
Sbjct: 439 ---ASLTSPSRP 447


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 53/200 (26%), Positives = 80/200 (40%), Gaps = 25/200 (12%)

Query: 396 LPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQ------------GGPR 443
           LP+ GG+AP PL+   P      +P  A L     QP P  PPQ                
Sbjct: 228 LPVGGGSAPGPLQSKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQN 287

Query: 444 QAQSPQPQRSG-SPSQQRLSPQGQQPLS---PQSGSPQQQRSPGSPQLSRASSGSSPNQA 499
             ++ + Q++G  P    ++P  Q       P S +P  Q  PG P   +    S P+  
Sbjct: 288 AVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLV 347

Query: 500 S--KPGATLA--SQPRPPVQGRSTSQQGEESKKPAP-PHPHLNKSQSLTNSL----STSD 550
           S   PG+ LA  +QP  P    + +  G     PA    P L   QS++N L       +
Sbjct: 348 STVAPGSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLE 407

Query: 551 TSQRGTPSEDEAKAETIRNL 570
             ++  P+  +A  +  R+L
Sbjct: 408 WQEKPKPASVDANTKLTRSL 427



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/142 (29%), Positives = 46/142 (32%), Gaps = 22/142 (15%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQ-------GGPRQAQSPQ 449
           P P GTA  P  P APQ     + G    GP L    P   PQ         P Q   P 
Sbjct: 605 PQPQGTAQPP--PGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPP 662

Query: 450 PQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQ 509
           PQ     S   L P G   L P       Q   G P L    + S P Q           
Sbjct: 663 PQ----ASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQL---------P 709

Query: 510 PRPPVQGRSTSQQGEESKKPAP 531
           PR P+ G+     G     P P
Sbjct: 710 PRAPLPGQMLLSGGPRGPVPQP 731



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 41/129 (31%), Positives = 46/129 (35%), Gaps = 17/129 (13%)

Query: 407 LRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQ 466
           LRP  PQ +       A      GQPQP+   Q  P   Q P    SG P      P G 
Sbjct: 585 LRPPQPQPQGTVGASGAT-----GQPQPQGTAQPPPGAPQGPPGAASGPP------PPGP 633

Query: 467 QPLSPQSGSPQQQRS----PGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQ 522
                  G+  Q RS    P  PQ       +S +    PGA  A  P PP QG    Q 
Sbjct: 634 ILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAP-ALLP-PPHQGLGQPQL 691

Query: 523 GEESKKPAP 531
           G     P P
Sbjct: 692 GPPLLHPPP 700



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 19/129 (14%)

Query: 425 LGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQ------Q 478
           LGP L + Q RP       +   PQPQ +   S     PQ Q    P  G+PQ       
Sbjct: 568 LGPIL-EDQARPSQNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGAAS 626

Query: 479 QRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKP-------AP 531
              P  P L   + G++P   S     L   P PP  G    Q      +P        P
Sbjct: 627 GPPPPGPILRPQNPGANPQLRS-----LLLNPPPPQTGVPPPQASLHHLQPPGAPALLPP 681

Query: 532 PHPHLNKSQ 540
           PH  L + Q
Sbjct: 682 PHQGLGQPQ 690


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 49/150 (32%), Positives = 64/150 (42%), Gaps = 35/150 (23%)

Query: 388 LVVSKMSQLPM---PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQ 444
           L  +++S LP    PGG +   +  W       + P Q Q      QPQ   PPQ  P Q
Sbjct: 339 LTSAELSSLPAFSSPGGLSLGNVTAW-------QQPQQPQ------QPQQPQPPQQQPPQ 385

Query: 445 AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGA 504
            Q PQPQ+   P Q +  PQ Q  L P S S      PGSP       G++    + P  
Sbjct: 386 PQQPQPQQ---PQQPQQPPQQQSHLVPVSLS---NLIPGSP---LPHVGAALTVTTHPHI 436

Query: 505 TLASQPRPPVQGRSTSQQGEESKKPAPPHP 534
           ++ S+P  P + RS          PAPP P
Sbjct: 437 SIKSEPVSPSRERS----------PAPPPP 456



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 36/146 (24%), Positives = 49/146 (33%), Gaps = 45/146 (30%)

Query: 419 SPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQ 478
           SPG   LG      QP+ P Q  P+Q Q PQ                QQP  PQ   PQQ
Sbjct: 352 SPGGLSLGNVTAWQQPQQPQQ--PQQPQPPQ----------------QQPPQPQQPQPQQ 393

Query: 479 QRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNK 538
            + P                            +PP Q          +  P  P PH+  
Sbjct: 394 PQQP---------------------------QQPPQQQSHLVPVSLSNLIPGSPLPHVGA 426

Query: 539 SQSLTNSLSTSDTSQRGTPSEDEAKA 564
           + ++T     S  S+  +PS + + A
Sbjct: 427 ALTVTTHPHISIKSEPVSPSRERSPA 452


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 45/158 (28%), Positives = 66/158 (41%), Gaps = 28/158 (17%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQ 451
           K+  +  P    P+PL P  PQ      PG   + P+L  P P P P   P    SP+P 
Sbjct: 136 KLGSVLSPESPKPTPLTPLEPQ-----KPGSV-VSPELQTPLPSPEPSK-PASVSSPEPP 188

Query: 452 RS------------GSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQL---SRASSGSSP 496
           +S             SP  Q+ +P   + +     +P+ Q+    P+      ASS  SP
Sbjct: 189 KSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESP 248

Query: 497 NQASKP---GATLASQPRPPVQGRSTSQQGEESKKPAP 531
             A+ P   G + A+ P      R+TS    E +KP+P
Sbjct: 249 VLAASPEPWGPSPAASPESRKSARTTS---PEPRKPSP 283



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 50/211 (23%), Positives = 79/211 (37%), Gaps = 29/211 (13%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQ--IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQ 449
           K++ +P P    P+P+ P + +  + + K   Q+     LG P    P    P  A SP+
Sbjct: 198 KLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPES--PVLAASPE 255

Query: 450 P---QRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATL 506
           P     + SP + R S +   P  P+  SP +   P  P  + +     P  A  PG+  
Sbjct: 256 PWGPSPAASP-ESRKSARTTSP-EPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWK 313

Query: 507 ASQPRPPVQGRSTSQQGEESKKPAPPHPHLNK--------------------SQSLTNSL 546
              P  P   +S         KPA P P ++                     S +   S 
Sbjct: 314 PGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSS 373

Query: 547 STSDTSQRGTPSEDEAKAETIRNLRKSFASL 577
           S S +S +  P+  E+       LRK+  +L
Sbjct: 374 SVSPSSWKSPPASPESWKSGPPELRKTAPTL 404



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 12/144 (8%)

Query: 389 VVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSP 448
           VVS   Q P+P   +P P +P      S  SP   +  P     +  P P   P   Q P
Sbjct: 162 VVSPELQTPLP---SPEPSKP-----ASVSSPEPPKSVPVCESQKLAPVPSPEP---QKP 210

Query: 449 QPQRSGSPSQQRLSPQGQ-QPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLA 507
            P    S      +P+ Q Q   P++  P    SP SP L+ +     P+ A+ P +  +
Sbjct: 211 APVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKS 270

Query: 508 SQPRPPVQGRSTSQQGEESKKPAP 531
           ++   P   + +  +  E  KP P
Sbjct: 271 ARTTSPEPRKPSPSESPEPWKPFP 294



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 47/159 (29%), Positives = 62/159 (38%), Gaps = 18/159 (11%)

Query: 392 KMSQLPMPGGTAPSPLR---PWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSP 448
           K ++   P    PSP     PW P    A SP   +  P +     +P P G PR  +S 
Sbjct: 269 KSARTTSPEPRKPSPSESPEPWKPF--PAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSN 326

Query: 449 QPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPG----SPQLSRAS---SGSSPNQASK 501
               SG     + +P     +SP    P    SPG    +P +S AS   S  SP+    
Sbjct: 327 PSASSGPWKPAKPAPS----VSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKS 382

Query: 502 PGATLASQPRPPVQGRSTSQQ-GEESKKPAPP-HPHLNK 538
           P A+  S    P + R T+     E  K  PP  P L K
Sbjct: 383 PPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK 421



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 25/159 (15%)

Query: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPP--QGGPRQAQ------SP 448
           P+P   +P P +P  P + SA S   + + P   +  P  P   + GP + +      SP
Sbjct: 350 PIPS-VSPGPWKP-TPSVSSA-SWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSP 406

Query: 449 QPQRSGSPSQQRLSPQGQQPLSPQ----SGSPQQQRSPGSPQLSRASSG---SSPNQASK 501
           +  ++  P    L   G  PLSP+    +GSP+ ++  GSP L + S     +SP     
Sbjct: 407 EHWKAVPPVSPELRKPGP-PLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDF 465

Query: 502 PGATLASQPRPPVQGRST------SQQGEESKKPAPPHP 534
           P +  +S+   P   +S+           E++KP P  P
Sbjct: 466 PESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGP 504


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 50/170 (29%), Positives = 67/170 (39%), Gaps = 13/170 (7%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG 454
           Q+P P   A  P+ P A     A  P  A    QL +P P+ PP       Q+     + 
Sbjct: 480 QVP-PSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPSPPAS 537

Query: 455 SPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
            P Q   SP    P+SP +  P Q      P L+       P+  + P  TL +  RPP 
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQ----APPVLAAPLLQVPPSPPASP--TLQAPRRPPT 591

Query: 515 QGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSD-----TSQRGTPSE 559
            G  TS  G        P P    S+S +++LS  D     +S   TP E
Sbjct: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 14/152 (9%)

Query: 393 MSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
           +S L  P   AP  L    P +++  SP  +     L  P P+ P        Q+P    
Sbjct: 386 LSPLATPPPQAPPALA--LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443

Query: 453 SGSPSQQRLSPQGQQPLSPQSGSPQQQ---------RSPGSPQLS--RASSGSSPNQASK 501
              P Q   SP    P+SP +  P Q          + P SP  S   + S + P QA  
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503

Query: 502 PGATLASQ-PRPPVQGRSTSQQGEESKKPAPP 532
           P A    Q  +PP Q             P+PP
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 9/145 (6%)

Query: 422 QAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRL----SPQGQQPLSPQSGSPQ 477
           +A+ G     P  R P    PR   SP+P    +P+  R+       G++PL+ ++G   
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 478 QQRSPGSPQLS---RASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHP 534
               P S   +   R++  SS N AS+P A+   +  PP +  S        +      P
Sbjct: 67  GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 535 HLNKSQSLTNSLSTSDTSQRGTPSE 559
                + L   +S  +T  RG  +E
Sbjct: 127 GPLGQKGL--RISAEETVARGKATE 149



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 39/174 (22%), Positives = 61/174 (35%), Gaps = 10/174 (5%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQ--PRPPPQGGPR-QAQSP 448
           K ++ P     +    R  +       SP  A+     G     PRP P   PR   + P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 449 QPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLAS 508
           +   S +       P       P +G   Q+  P S  LS  SS +  +  ++ G +   
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQR--PASRSLS--SSATPLSSPARSGPSARG 261

Query: 509 QPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEA 562
            PR P        +G ++ +P    P    +      LS+S  +   TPS   A
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSAA 312



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 48/177 (27%), Positives = 62/177 (35%), Gaps = 38/177 (21%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQG------GPRQ 444
           S  + LPM     P P  P        + P      P L  P+ RPP  G      GPR 
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR-RPPTPGPDTSVSGPRL 603

Query: 445 ----AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRS-------------PGSPQL 487
               A  P P  S SPS     P      S  + +P++ R              P   +L
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663

Query: 488 SRA-----SSGSSPNQASKPGATLASQPRPPVQGRSTSQ--------QGEESKKPAP 531
           +       S G +P  A + GA  A  P PP  G  ++         +G ES  PAP
Sbjct: 664 AACHPAAWSRGPAPPLAFR-GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 36/149 (24%), Positives = 46/149 (30%), Gaps = 4/149 (2%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQ 458
           P   A  PL P A     A +     L      P P PP Q       SP    S +P  
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468

Query: 459 QR----LSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
           Q      +P  Q P SP +  P    +   PQ     +      A  P     +   PP+
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 528

Query: 515 QGRSTSQQGEESKKPAPPHPHLNKSQSLT 543
           Q   +       + P  P   L  S   T
Sbjct: 529 QALPSPPASFPGQAPFSPSASLPMSPLAT 557



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 43/150 (28%), Positives = 61/150 (40%), Gaps = 25/150 (16%)

Query: 408 RPWAPQIKSAKSP--GQAQLGPQL-GQPQ-PRPPPQGGPRQAQSPQPQRSGSPSQQR--- 460
           RP +  + S+ +P    A+ GP   G P+ P  P Q  P+  Q+ +P +   P +     
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 461 LSPQGQQPLSPQSGSP--QQQRSPGSPQLSRASSGS---------SPNQASKPGA--TLA 507
           L P    PL+  S S   Q Q  P  P    +SS +         +P   S P +  TL 
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355

Query: 508 SQPRPPVQGRSTS-----QQGEESKKPAPP 532
           S P  P    +TS      Q   S  P+PP
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPP 385



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 397 PMPGGTAPSPLRPWAPQ-----------IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQA 445
           P+    AP    PW P            I   + P  A   P    P P P   GG   A
Sbjct: 678 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737

Query: 446 QSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRA-----SSGSSPNQAS 500
            +     S SP Q RL   G+ PL     S  Q     +  L+ A      SG  P  A 
Sbjct: 738 GAGAGASSRSPKQARL---GELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 794

Query: 501 KPGAT 505
             G T
Sbjct: 795 GGGVT 799


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 50/170 (29%), Positives = 67/170 (39%), Gaps = 13/170 (7%)

Query: 395 QLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSG 454
           Q+P P   A  P+ P A     A  P  A    QL +P P+ PP       Q+     + 
Sbjct: 441 QVP-PSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPSPPAS 498

Query: 455 SPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
            P Q   SP    P+SP +  P Q      P L+       P+  + P  TL +  RPP 
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQ----APPVLAAPLLQVPPSPPASP--TLQAPRRPPT 552

Query: 515 QGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSD-----TSQRGTPSE 559
            G  TS  G        P P    S+S +++LS  D     +S   TP E
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 602



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 14/152 (9%)

Query: 393 MSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQR 452
           +S L  P   AP  L    P +++  SP  +     L  P P+ P        Q+P    
Sbjct: 347 LSPLATPPPQAPPALA--LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404

Query: 453 SGSPSQQRLSPQGQQPLSPQSGSPQQQ---------RSPGSPQLS--RASSGSSPNQASK 501
              P Q   SP    P+SP +  P Q          + P SP  S   + S + P QA  
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464

Query: 502 PGATLASQ-PRPPVQGRSTSQQGEESKKPAPP 532
           P A    Q  +PP Q             P+PP
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 46/182 (25%), Positives = 74/182 (40%), Gaps = 20/182 (10%)

Query: 408 RPWAPQIKSAKSP--GQAQLGPQL-GQPQ-PRPPPQGGPRQAQSPQPQRSGSPSQQR--- 460
           RP +  + S+ +P    A+ GP   G P+ P  P Q  P+  Q+ +P +   P +     
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286

Query: 461 LSPQGQQPL-SPQSGSPQQQRSPGSPQLSRASSGSSPNQASKP------GATLASQPRPP 513
           L P    PL +P   +P    +P S Q   +   + P+QA+         AT +  P PP
Sbjct: 287 LGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346

Query: 514 VQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSEDEAKAETIRNLRKS 573
           +   +T          APP   L   Q+  +  ++   S   TPS     A  +  L+  
Sbjct: 347 LSPLAT------PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400

Query: 574 FA 575
           F+
Sbjct: 401 FS 402



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 48/177 (27%), Positives = 62/177 (35%), Gaps = 38/177 (21%)

Query: 391 SKMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQG------GPRQ 444
           S  + LPM     P P  P        + P      P L  P+ RPP  G      GPR 
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR-RPPTPGPDTSVSGPRL 564

Query: 445 ----AQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRS-------------PGSPQL 487
               A  P P  S SPS     P      S  + +P++ R              P   +L
Sbjct: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624

Query: 488 SRA-----SSGSSPNQASKPGATLASQPRPPVQGRSTSQ--------QGEESKKPAP 531
           +       S G +P  A + GA  A  P PP  G  ++         +G ES  PAP
Sbjct: 625 AACHPAAWSRGPAPPLAFR-GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 680



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 38/170 (22%), Positives = 60/170 (35%), Gaps = 10/170 (5%)

Query: 392 KMSQLPMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQ--PRPPPQGGPR-QAQSP 448
           K ++ P     +    R  +       SP  A+     G     PRP P   PR   + P
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196

Query: 449 QPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLAS 508
           +   S +       P       P +G   Q+  P S  LS  SS +  +  ++ G +   
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQR--PASRSLS--SSATPLSSPARSGPSARG 252

Query: 509 QPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
            PR P        +G ++ +P    P    +      LS+S  +   TPS
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPS 299



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 36/149 (24%), Positives = 46/149 (30%), Gaps = 4/149 (2%)

Query: 399 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQ 458
           P   A  PL P A     A +     L      P P PP Q       SP    S +P  
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429

Query: 459 QR----LSPQGQQPLSPQSGSPQQQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPV 514
           Q      +P  Q P SP +  P    +   PQ     +      A  P     +   PP+
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489

Query: 515 QGRSTSQQGEESKKPAPPHPHLNKSQSLT 543
           Q   +       + P  P   L  S   T
Sbjct: 490 QALPSPPASFPGQAPFSPSASLPMSPLAT 518



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 31/142 (21%), Positives = 56/142 (39%), Gaps = 12/142 (8%)

Query: 422 QAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRL----SPQGQQPLSPQSGSPQ 477
           +A+ G     P  R P    PR   SP+P    +P+  R+       G++PL+ ++G   
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG--- 63

Query: 478 QQRSPGSPQLSRASSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLN 537
                G   +  ++  + P + S+P A+   +  PP +  S        +      P   
Sbjct: 64  ---GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 120

Query: 538 KSQSLTNSLSTSDTSQRGTPSE 559
             + L   +S  +T  RG  +E
Sbjct: 121 GQKGL--RISAEETVARGKATE 140



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 397 PMPGGTAPSPLRPWAPQ-----------IKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQA 445
           P+    AP    PW P            I   + P  A   P    P P P   GG   A
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698

Query: 446 QSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRA-----SSGSSPNQAS 500
            +     S SP Q RL   G+ PL     S  Q     +  L+ A      SG  P  A 
Sbjct: 699 GAGAGASSRSPKQARL---GELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 755

Query: 501 KPGAT 505
             G T
Sbjct: 756 GGGVT 760


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.128    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,111,376
Number of Sequences: 37866
Number of extensions: 1608577
Number of successful extensions: 21060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 309
Number of HSP's successfully gapped in prelim test: 1914
Number of HSP's that attempted gapping in prelim test: 10745
Number of HSP's gapped (non-prelim): 8012
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press