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Search of human proteins with 208610000
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]
(579 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens] 1171 0.0
gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] 1109 0.0
gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens] 771 0.0
gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens] 771 0.0
gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens] 764 0.0
gi|45827806 atlastin 3 [Homo sapiens] 705 0.0
gi|14149631 ring finger protein 112 [Homo sapiens] 86 7e-17
gi|31377634 guanylate binding protein 4 [Homo sapiens] 74 3e-13
gi|148234215 guanylate binding protein 4-like [Homo sapiens] 73 8e-13
gi|197333737 guanylate-binding protein 5 [Homo sapiens] 72 2e-12
gi|16418425 guanylate-binding protein 5 [Homo sapiens] 72 2e-12
gi|112382372 guanylate binding protein 3 [Homo sapiens] 70 5e-12
gi|38327558 guanylate binding protein 2, interferon-inducible [H... 68 2e-11
gi|157671915 guanylate binding protein family, member 6 [Homo sa... 67 6e-11
gi|166706903 guanylate binding protein 1, interferon-inducible, ... 63 8e-10
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 36 0.085
gi|4758942 septin 4 isoform 1 [Homo sapiens] 32 1.2
gi|17986247 septin 4 isoform 3 [Homo sapiens] 32 1.2
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 32 1.2
gi|21729876 ATP-binding cassette, sub-family C, member 11 isofor... 31 2.7
gi|21729873 ATP-binding cassette, sub-family C, member 11 isofor... 31 2.7
gi|15149474 ATP-binding cassette, sub-family C, member 11 isofor... 31 2.7
gi|225543474 myotubularin related protein 7 [Homo sapiens] 30 4.7
gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a ... 30 4.7
gi|32967591 phosducin isoform a [Homo sapiens] 30 6.1
gi|12408668 phosducin isoform b [Homo sapiens] 30 6.1
gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ... 30 6.1
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 30 7.9
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 30 7.9
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 30 7.9
>gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]
Length = 579
Score = 1171 bits (3030), Expect = 0.0
Identities = 579/579 (100%), Positives = 579/579 (100%)
Query: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60
MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP
Sbjct: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60
Query: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120
VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN
Sbjct: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120
Query: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180
KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS
Sbjct: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180
Query: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240
QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM
Sbjct: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240
Query: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300
FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG
Sbjct: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300
Query: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360
LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI
Sbjct: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360
Query: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420
KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD
Sbjct: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420
Query: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480
LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA
Sbjct: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480
Query: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540
VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET
Sbjct: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540
Query: 541 LWEQVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKKKN 579
LWEQVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKKKN
Sbjct: 541 LWEQVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKKKN 579
>gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens]
Length = 583
Score = 1109 bits (2868), Expect = 0.0
Identities = 547/571 (95%), Positives = 557/571 (97%)
Query: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60
MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP
Sbjct: 1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCP 60
Query: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120
VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN
Sbjct: 61 VQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYN 120
Query: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180
KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS
Sbjct: 121 KDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDS 180
Query: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240
QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM
Sbjct: 181 QSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLM 240
Query: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300
FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG
Sbjct: 241 FLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPG 300
Query: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360
LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI
Sbjct: 301 LKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYI 360
Query: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420
KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD
Sbjct: 361 KIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLD 420
Query: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480
LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA
Sbjct: 421 LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAARTPATLFA 480
Query: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540
VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET
Sbjct: 481 VMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIGTVIDQIAET 540
Query: 541 LWEQVFSKLFEVTRRRMVHRALSSAQRQRLS 571
LWEQV L + + ++++++ + L+
Sbjct: 541 LWEQVLKPLGDNLMEENIRQSVTNSIKAGLT 571
>gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 771 bits (1990), Expect = 0.0
Identities = 363/528 (68%), Positives = 447/528 (84%), Gaps = 3/528 (0%)
Query: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111
+E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+
Sbjct: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84
Query: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171
DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL
Sbjct: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144
Query: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231
MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE
Sbjct: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204
Query: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291
+ KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+
Sbjct: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264
Query: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR
Sbjct: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324
Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411
LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP
Sbjct: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384
Query: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471
+DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A
Sbjct: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444
Query: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531
ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G
Sbjct: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504
Query: 532 TVIDQIAETLWEQVFSKLFE--VTRRRMVHRALSSAQRQRLSSNNNKK 577
VIDQ+A LW+Q KL+ T R + H+A + + + + KK
Sbjct: 505 AVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKK 552
>gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 771 bits (1990), Expect = 0.0
Identities = 363/528 (68%), Positives = 447/528 (84%), Gaps = 3/528 (0%)
Query: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111
+E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+
Sbjct: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84
Query: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171
DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL
Sbjct: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144
Query: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231
MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE
Sbjct: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204
Query: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291
+ KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+
Sbjct: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264
Query: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR
Sbjct: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324
Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411
LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP
Sbjct: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384
Query: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471
+DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A
Sbjct: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444
Query: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531
ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G
Sbjct: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504
Query: 532 TVIDQIAETLWEQVFSKLFE--VTRRRMVHRALSSAQRQRLSSNNNKK 577
VIDQ+A LW+Q KL+ T R + H+A + + + + KK
Sbjct: 505 AVIDQVAAALWDQALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKK 552
>gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens]
Length = 558
Score = 764 bits (1974), Expect = 0.0
Identities = 363/533 (68%), Positives = 447/533 (83%), Gaps = 8/533 (1%)
Query: 52 DEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLL 111
+E +KK PVQ+++ +DDH+FELDE AL +ILL E +RD +V VSVAGAFRKGKSFL+
Sbjct: 26 EEPVKKAGPVQVLIV-KDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLM 84
Query: 112 DFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLL 171
DFMLRYMYN++S W+G NEPLTGF+WRGG ERETTGIQ+W+E+F+I++P+G KVAVLL
Sbjct: 85 DFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIFLINKPDGKKVAVLL 144
Query: 172 MDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEI 231
MDTQG FDSQST++D ATVFALSTM SS+QVYNLSQN+QEDDLQHLQLFTEYGRLAMEE
Sbjct: 145 MDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEET 204
Query: 232 YQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNL 291
+ KPFQ+L+FL+RDWS+PYE SYG +GG +FLEKRL+V NQHEELQNVRKHIH+CF+N+
Sbjct: 205 FLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNI 264
Query: 292 GCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
CFLLPHPGLKVATNP+FDG+LK+ID++F + L+ L+P LL+PE+L KEI+G+K+TCR
Sbjct: 265 SCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRG 324
Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAP 411
LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVA A+DTY K ME++CGGDKP++AP
Sbjct: 325 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAP 384
Query: 412 SDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYA 471
+DL+ KHL LKE ++K FR VKKMGG+EF RRY QLE+EI+E Y +IKHND KNIF+A
Sbjct: 385 NDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHA 444
Query: 472 ARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG 531
ARTPATLF V+F Y+I+G+TGFIGL+ IA LCN++MGL LI LCTWAY++YSGE+RE+G
Sbjct: 445 ARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELG 504
Query: 532 TVIDQIAETLWEQ-----VFSKLFE--VTRRRMVHRALSSAQRQRLSSNNNKK 577
VIDQ+A LW+Q KL+ T R + H+A + + + + KK
Sbjct: 505 AVIDQVAAALWDQGSTNEALYKLYSAAATHRHLYHQAFPTPKSESTEQSEKKK 557
>gi|45827806 atlastin 3 [Homo sapiens]
Length = 541
Score = 705 bits (1820), Expect = 0.0
Identities = 337/509 (66%), Positives = 417/509 (81%), Gaps = 5/509 (0%)
Query: 51 SDEVMK--KPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKS 108
+D+ M+ KP PVQ+VL +D H+FELDE+AL ILLQ+HIRDL++VVVSVAGAFRKGKS
Sbjct: 15 ADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKS 74
Query: 109 FLLDFMLRYMYNKDSQ---SWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGT 165
F+LDFMLRY+Y++ +W+G EPLTGF+WRGG + ETTGIQ+W+EVF +++P G
Sbjct: 75 FILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGK 134
Query: 166 KVAVLLMDTQGAFDSQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGR 225
KVAV+LMDTQGAFDSQST+KDCAT+FALSTMTSSVQ+YNLSQNIQEDDLQ LQLFTEYGR
Sbjct: 135 KVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGR 194
Query: 226 LAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKHIH 285
LAM+EI+QKPFQTLMFL+RDWS+PYE+SYGL+GG FL+KRLQVK++QHEE+QNVR HIH
Sbjct: 195 LAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIH 254
Query: 286 NCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGS 345
+CFS++ CFLLPHPGL+VAT+P FDG+LKDI +FK +L+ L+P +L P L+EKEI+GS
Sbjct: 255 SCFSDVTCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGS 314
Query: 346 KVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCGGD 405
KVTCR L+EYFKAYIKIYQGE+LPHPKSMLQATAEANNLAA A A+D Y +ME+VCGG+
Sbjct: 315 KVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGE 374
Query: 406 KPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDG 465
KPY++P LE KH + K++A+ F+ KKMGG +F RYQ +LE EI+E Y NF KHN
Sbjct: 375 KPYLSPDILEEKHCEFKQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGS 434
Query: 466 KNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSG 525
KN+F RTPA LF + A+YI SGLTGFIGL +A L N ++GL LI L TW Y++YSG
Sbjct: 435 KNVFSTFRTPAVLFTGIVALYIASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSG 494
Query: 526 EFREIGTVIDQIAETLWEQVFSKLFEVTR 554
++RE+G ID A + EQ S + T+
Sbjct: 495 QYRELGGAIDFGAAYVLEQASSHIGNSTQ 523
>gi|14149631 ring finger protein 112 [Homo sapiens]
Length = 632
Score = 86.3 bits (212), Expect = 7e-17
Identities = 71/248 (28%), Positives = 116/248 (46%), Gaps = 17/248 (6%)
Query: 79 ALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSW--IGGNNEPLTG 136
A+ + L RD + +++V G GKSFLL+ +L+ + +S G L G
Sbjct: 154 AINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLESGEGGRPRGGEASLQG 213
Query: 137 FTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALSTM 196
W G GI +W+ F++ + G KVAV L+DT A + + + + AL+TM
Sbjct: 214 CRW--GANGLARGIWMWSHPFLLGK-EGKKVAVFLVDTGDAMSPELSRETRIKLCALTTM 270
Query: 197 TSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGL 256
SS Q+ + SQ +++ DL +L++F + + P Q L L+RD S+P + G
Sbjct: 271 LSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPNKAGQGH 330
Query: 257 EGGKQFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDI 316
G + +RL + + +EL ++ C LLP PG + N D
Sbjct: 331 VGN---IFQRLSGRYPKVQELLQGKR--------ARCCLLPAPGRR-RMNQGHASPGGDT 378
Query: 317 DEDFKREL 324
D+DF+ L
Sbjct: 379 DDDFRHLL 386
>gi|31377634 guanylate binding protein 4 [Homo sapiens]
Length = 640
Score = 74.3 bits (181), Expect = 3e-13
Identities = 101/438 (23%), Positives = 181/438 (41%), Gaps = 53/438 (12%)
Query: 51 SDEVMKKPCPVQIVLAHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFL 110
S+ +M P I L + ++ +ALE + + I +VVV++ G +R GKS+L
Sbjct: 18 SESIMMAP----ICLVENQEEQLTVNSKALE---ILDKISQ-PVVVVAIVGLYRTGKSYL 69
Query: 111 LDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVL 170
++ + G N GF + ET GI +W V + +PN T V
Sbjct: 70 MNRLA------------GKRN----GFPLGSTVQSETKGIWMWC-VPHLSKPNHTLV--- 109
Query: 171 LMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAME 229
L+DT+G D +S K+ + +FAL+ + SS VYN I L+ L TE L
Sbjct: 110 LLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRA 169
Query: 230 EIYQKP------------FQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEEL 277
+ +P F ++ +RD++ + ++LE L++ ++ ++
Sbjct: 170 KSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKI 229
Query: 278 QN---VRKHIHNCFSNLGCFLLPHP-GLKVATNPSFDGRLKDIDEDFKRELRNLVPLLLA 333
QN R+ I + F CF+ P K N + ++++ F + N +
Sbjct: 230 QNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFT 289
Query: 334 PENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDT 393
+ G VT + L Y+ +P ++ + A A+ N AAV A D
Sbjct: 290 HAK-TKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADH 348
Query: 394 YCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KKMGGDEFCRRYQDQLEAEI 452
Y + M Q P+D ++ LD+ ++ +V + + +Q +L I
Sbjct: 349 YSQQMAQ------QLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTI 402
Query: 453 EETYANFIKHNDGKNIFY 470
E+ +F+ N+ + Y
Sbjct: 403 EKKKGDFVLQNEEASAKY 420
>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
Length = 638
Score = 72.8 bits (177), Expect = 8e-13
Identities = 89/395 (22%), Positives = 163/395 (41%), Gaps = 45/395 (11%)
Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
+VVV++ G +R GKS+L+ NK + G N+ GF + ET GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFPLGCTVKSETKGIWMW 81
Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFDSQ-STIKDCATVFALSTMTSSVQVYNLSQNIQED 212
+ P+ ++L+DT+G D + S K + +FAL+ + SS VYN I
Sbjct: 82 ----CVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAVLLSSSFVYNSMGTINHQ 137
Query: 213 DLQHLQLFTEYGRLAMEEIYQKP------------FQTLMFLIRDWSYPYEHSYGLEGGK 260
L+ L TE L + +P F ++ +RD++ +
Sbjct: 138 ALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTVRDFTLELKLDGHPITED 197
Query: 261 QFLEKRLQVKQNQHEELQN---VRKHIHNCFSNLGCFLLPHP-GLKVATNPSFDGRLKDI 316
++LE L++ ++ ++QN R+ I + F CF+ P K + R +
Sbjct: 198 EYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPINDKKLLLHVEEVREDQL 257
Query: 317 DEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQ 376
D +F+ + N + + G VT L + Y+ P ++ +
Sbjct: 258 DSNFQMQSENFCSYIFTHAK-TKTLREGILVTGNRLGMLVETYLDAINSGATPCLENAMA 316
Query: 377 ATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KKM 435
A+ N AAV A + Y + M Q P+D ++ LD+ V ++ +V +
Sbjct: 317 VLAQCENSAAVQRAANHYSQQMAQ------QVRFPTDTLQELLDVHAVCEREAIAVFMEY 370
Query: 436 GGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFY 470
+ + +Q +L +E+ +F+ N+ + Y
Sbjct: 371 SFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKY 405
>gi|197333737 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 71.6 bits (174), Expect = 2e-12
Identities = 92/389 (23%), Positives = 163/389 (41%), Gaps = 48/389 (12%)
Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
+VVV++ G +R GKS+L+ NK + G N+ GF+ + T GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFSVASTVQSHTKGIWIW 81
Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
+ PN ++L+DT+G D ++ K+ +FAL+ + SS VYN I +
Sbjct: 82 ----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQG 137
Query: 213 DLQHLQLFTEYGRLAME------EIYQKP------FQTLMFLIRDWSYPYEHSYGLEGGK 260
+ L TE L + + P F L++ +RD+ E L
Sbjct: 138 AIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPD 197
Query: 261 QFLEKRLQVKQNQHEELQNV---RKHIHNCFSNLGCFL--LPHPGLKVATNPSFDGRLKD 315
++LE L+ KQ + +QN R I F CF+ LP K+A + +
Sbjct: 198 EYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD--DE 255
Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSML 375
++ +F +++ + + ++ + G V L Y+ +LP ++ +
Sbjct: 256 LEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAV 314
Query: 376 QATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KK 434
A A+ N AAV A Y + M G K + P + ++ LDL + ++ V K
Sbjct: 315 LALAQRENSAAVQKAIAHYDQQM-----GQKVQL-PMETLQELLDLHRTSEREAIEVFMK 368
Query: 435 MGGDEFCRRYQDQLEAEIEETYANFIKHN 463
+ + +Q +LE ++ + K N
Sbjct: 369 NSFKDVDQSFQKELETLLDAKQNDICKRN 397
>gi|16418425 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 71.6 bits (174), Expect = 2e-12
Identities = 92/389 (23%), Positives = 163/389 (41%), Gaps = 48/389 (12%)
Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
+VVV++ G +R GKS+L+ NK + G N+ GF+ + T GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFSVASTVQSHTKGIWIW 81
Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
+ PN ++L+DT+G D ++ K+ +FAL+ + SS VYN I +
Sbjct: 82 ----CVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQG 137
Query: 213 DLQHLQLFTEYGRLAME------EIYQKP------FQTLMFLIRDWSYPYEHSYGLEGGK 260
+ L TE L + + P F L++ +RD+ E L
Sbjct: 138 AIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPD 197
Query: 261 QFLEKRLQVKQNQHEELQNV---RKHIHNCFSNLGCFL--LPHPGLKVATNPSFDGRLKD 315
++LE L+ KQ + +QN R I F CF+ LP K+A + +
Sbjct: 198 EYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPD--DE 255
Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSML 375
++ +F +++ + + ++ + G V L Y+ +LP ++ +
Sbjct: 256 LEPEFVQQVTEFCSYIFS-HSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAV 314
Query: 376 QATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-KK 434
A A+ N AAV A Y + M G K + P + ++ LDL + ++ V K
Sbjct: 315 LALAQRENSAAVQKAIAHYDQQM-----GQKVQL-PMETLQELLDLHRTSEREAIEVFMK 368
Query: 435 MGGDEFCRRYQDQLEAEIEETYANFIKHN 463
+ + +Q +LE ++ + K N
Sbjct: 369 NSFKDVDQSFQKELETLLDAKQNDICKRN 397
>gi|112382372 guanylate binding protein 3 [Homo sapiens]
Length = 595
Score = 70.1 bits (170), Expect = 5e-12
Identities = 92/390 (23%), Positives = 166/390 (42%), Gaps = 50/390 (12%)
Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
+VVV++ G +R GKS+L+ NK + G N+ GF+ + T GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLM--------NK-----LAGKNK---GFSLGSTVKSHTKGIWMW 81
Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
+ P + ++L+DT+G D + ++ + +F L+ + SS VYN I +
Sbjct: 82 ----CVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTINQQ 137
Query: 213 DLQHLQLFTEYGRLAMEEI------------YQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260
+ L TE + + F ++ +RD+S E
Sbjct: 138 AMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPD 197
Query: 261 QFLEKRLQVKQNQHEELQNV---RKHIHNCFSNLGCFL--LPHPGLKVATNPSFDGRLKD 315
++LE L++ Q ++ +N R I F CF+ LP K+A ++
Sbjct: 198 EYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQD--EE 255
Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSM 374
+D +F +++ + + + N K +SG KV L YI +LP ++
Sbjct: 256 LDPEFVQQVADFCSYIFS--NSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENA 313
Query: 375 LQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSV-K 433
+ A A+ N AAV A Y + M G K + P++ ++ LDL V+ ++ V
Sbjct: 314 VLALAQIENSAAVQKAIAHYDQQM-----GQKVQL-PAETLQELLDLHRVSEREATEVYM 367
Query: 434 KMGGDEFCRRYQDQLEAEIEETYANFIKHN 463
K + +Q +L A++++ +F K N
Sbjct: 368 KNSFKDVDHLFQKKLAAQLDKKRDDFCKQN 397
>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
sapiens]
Length = 591
Score = 68.2 bits (165), Expect = 2e-11
Identities = 87/387 (22%), Positives = 160/387 (41%), Gaps = 44/387 (11%)
Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
+VVV++ G +R GKS+L++ + G N GF+ + T GI +W
Sbjct: 38 VVVVAIVGLYRTGKSYLMNKL------------AGKKN----GFSLGSTVKSHTKGIWMW 81
Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
+ P + ++L+DT+G D + ++ + +FAL+ + SS VYN I +
Sbjct: 82 ----CVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQ 137
Query: 213 DLQHLQLFTEY----------GRLAMEEI--YQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260
+ L TE G ++++ + F ++ +RD++ E
Sbjct: 138 AMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITAD 197
Query: 261 QFLEKRLQVKQ---NQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDID 317
+LE L++++ + + + R I F CF+ P K + ++++
Sbjct: 198 DYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELN 257
Query: 318 EDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSMLQ 376
DF ++ +L+ N+ K +SG V L Y+ +LP ++ +
Sbjct: 258 PDFIEQVAEFCSYILSHSNV--KTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVL 315
Query: 377 ATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMG 436
A A+ N AAV A Y + M Q P +L H D + AI+ F K
Sbjct: 316 ALAQIENSAAVEKAIAHYEQQMGQKV--QLPTETLQELLDLHRDSEREAIEVF---MKNS 370
Query: 437 GDEFCRRYQDQLEAEIEETYANFIKHN 463
+ + +Q +L A++E +F K N
Sbjct: 371 FKDVDQMFQRKLGAQLEARRDDFCKQN 397
>gi|157671915 guanylate binding protein family, member 6 [Homo
sapiens]
Length = 633
Score = 66.6 bits (161), Expect = 6e-11
Identities = 82/349 (23%), Positives = 141/349 (40%), Gaps = 44/349 (12%)
Query: 75 LDEEALEQILL-QEHIRDLN-----IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIG 128
L E EQ+L+ Q+ I+ L +VVV++ G +R GKS+L++ +
Sbjct: 13 LVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHL-------------A 59
Query: 129 GNNEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDC 187
G N GF + ET GI +W + P+ ++L+DT+G D + K+
Sbjct: 60 GQNH---GFPLGSTVQSETKGIWMW----CVPHPSKPNHTLVLLDTEGLGDVEKGDPKND 112
Query: 188 ATVFALSTMTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKP------------ 235
+ +FAL+ + S VYN I L+ L TE L + +P
Sbjct: 113 SWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSF 172
Query: 236 FQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQN---VRKHIHNCFSNLG 292
F ++ +RD++ + + ++LE L++ Q + +Q R+ I F
Sbjct: 173 FPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRK 232
Query: 293 CFLLPHPGLKVATNPSFDG-RLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRD 351
CF+ P + + K +D F +E N+ + + G VT
Sbjct: 233 CFVFDRPTNDKDLLANIEKVSEKQLDPKF-QEQTNIFCSYIFTHARTKTLREGITVTGNR 291
Query: 352 LVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQ 400
L Y++ +P ++ + A+ N AAV A D Y + M Q
Sbjct: 292 LGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQ 340
>gi|166706903 guanylate binding protein 1, interferon-inducible,
67kDa [Homo sapiens]
Length = 592
Score = 62.8 bits (151), Expect = 8e-10
Identities = 91/390 (23%), Positives = 162/390 (41%), Gaps = 48/390 (12%)
Query: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
+VVV++ G +R GKS+L+ NK + G + GF+ + T GI +W
Sbjct: 38 MVVVAIVGLYRTGKSYLM--------NK-----LAGKKK---GFSLGSTVQSHTKGIWMW 81
Query: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
+ P ++L+DT+G D + ++ + +FAL+ + SS VYN I +
Sbjct: 82 ----CVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
Query: 213 DLQHLQLFTEY--------------GRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258
+ L TE + + F ++ +RD+S E
Sbjct: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLT 197
Query: 259 GKQFLEKRLQVKQ--NQHEELQNV-RKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKD 315
++L L++K+ +Q +E N+ R I F CF+ P + + ++
Sbjct: 198 PDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEE 257
Query: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSM 374
+D +F +++ + + + N K +SG +V L Y+ +LP ++
Sbjct: 258 LDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENA 315
Query: 375 LQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQF-RSVK 433
+ A A+ N AAV A Y + M Q P +L H D + AI+ F RS
Sbjct: 316 VLALAQIENSAAVQKAIAHYEQQMGQKV--QLPTETLQELLDLHRDSEREAIEVFIRSSF 373
Query: 434 KMGGDEFCRRYQDQLEAEIEETYANFIKHN 463
K + +Q +L A++E+ +F K N
Sbjct: 374 K----DVDHLFQKELAAQLEKKRDDFCKQN 399
>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
Length = 625
Score = 36.2 bits (82), Expect = 0.085
Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Query: 224 GRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGKQFLEKRLQVKQNQHEELQNVRKH 283
G++ E+ + +TL + + + ++G K + E+RL+ + + EELQ+VR
Sbjct: 436 GQIREEKARTRELETLQQTVEELQ---AQVHSMDGAKGWFERRLKEAEGKEEELQDVRDQ 492
Query: 284 IHNCFSNLGCFLLPHPGLKVATNPSFDGR 312
+ C L LK + DG+
Sbjct: 493 LEQAQEERDCHLKTISSLKQEVKDTVDGQ 521
>gi|4758942 septin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 309 FDGRLKDIDEDFKRELR---NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQ 364
F L+ +D +F + L N+VP+L + L E+ K R+ +E+F IKIYQ
Sbjct: 263 FGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFG--IKIYQ 319
>gi|17986247 septin 4 isoform 3 [Homo sapiens]
Length = 459
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 309 FDGRLKDIDEDFKRELR---NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQ 364
F L+ +D +F + L N+VP+L + L E+ K R+ +E+F IKIYQ
Sbjct: 244 FGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFG--IKIYQ 300
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 32.3 bits (72), Expect = 1.2
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 415 ERKHLD--LKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANFIKHNDGKNIFYAA 472
ER+ LD KEVA+ + KM +E CR+Y + + A I DG N
Sbjct: 18 ERRDLDDLKKEVAMTEH----KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNAL--T 71
Query: 473 RTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGL 510
P T V F + G + + + A+LC L G+
Sbjct: 72 PPPTTPEWVKFCRQLFGGFSILLWIG--AILCFLAYGI 107
>gi|21729876 ATP-binding cassette, sub-family C, member 11 isoform b
[Homo sapiens]
Length = 1344
Score = 31.2 bits (69), Expect = 2.7
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 474 TPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG-- 531
T A+L + Y I G T FI A+LC L++ +F+ A VK E+
Sbjct: 284 TCASLVICSISSYFIIGYTAFI-----AILCYLLVFPLAVFMTRMA-VKAQHHTSEVSDQ 337
Query: 532 ---------TVIDQIAETLWEQVFSKLFEVTRRR 556
T I I WE+ F+K+ E RR+
Sbjct: 338 RIRVTSEVLTCIKLIKMYTWEKPFAKIIEDLRRK 371
>gi|21729873 ATP-binding cassette, sub-family C, member 11 isoform a
[Homo sapiens]
Length = 1382
Score = 31.2 bits (69), Expect = 2.7
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 474 TPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG-- 531
T A+L + Y I G T FI A+LC L++ +F+ A VK E+
Sbjct: 284 TCASLVICSISSYFIIGYTAFI-----AILCYLLVFPLAVFMTRMA-VKAQHHTSEVSDQ 337
Query: 532 ---------TVIDQIAETLWEQVFSKLFEVTRRR 556
T I I WE+ F+K+ E RR+
Sbjct: 338 RIRVTSEVLTCIKLIKMYTWEKPFAKIIEDLRRK 371
>gi|15149474 ATP-binding cassette, sub-family C, member 11 isoform a
[Homo sapiens]
Length = 1382
Score = 31.2 bits (69), Expect = 2.7
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 474 TPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAYVKYSGEFREIG-- 531
T A+L + Y I G T FI A+LC L++ +F+ A VK E+
Sbjct: 284 TCASLVICSISSYFIIGYTAFI-----AILCYLLVFPLAVFMTRMA-VKAQHHTSEVSDQ 337
Query: 532 ---------TVIDQIAETLWEQVFSKLFEVTRRR 556
T I I WE+ F+K+ E RR+
Sbjct: 338 RIRVTSEVLTCIKLIKMYTWEKPFAKIIEDLRRK 371
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 30.4 bits (67), Expect = 4.7
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 520 YVKYSGEFREIGTVIDQIAETLWE--QVFSKLFEVTRRRMVH--RALSSAQRQRLSSNNN 575
Y G+ +EI VIDQ E +W+ + F FE R ++H + S Q N+
Sbjct: 385 YGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQ 444
Query: 576 KKK 578
K++
Sbjct: 445 KER 447
>gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a
[Homo sapiens]
Length = 1701
Score = 30.4 bits (67), Expect = 4.7
Identities = 13/29 (44%), Positives = 19/29 (65%)
Query: 357 KAYIKIYQGEELPHPKSMLQATAEANNLA 385
+ Y+ QG ELP+PKS+L A + + LA
Sbjct: 695 RCYLASLQGGELPNPKSLLAAASRPSKLA 723
>gi|32967591 phosducin isoform a [Homo sapiens]
Length = 246
Score = 30.0 bits (66), Expect = 6.1
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 16/107 (14%)
Query: 199 SVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258
S+Q Y L +ED+ +Y R M++++QK L F R Y Y LE
Sbjct: 73 SIQEYELIHKEKEDE----NCLRKYRRQCMQDMHQK----LSFGPR-----YGFVYELET 119
Query: 259 GKQFL---EKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLK 302
GKQFL EK L++ ++ K S+L C +P +K
Sbjct: 120 GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVK 166
>gi|12408668 phosducin isoform b [Homo sapiens]
Length = 194
Score = 30.0 bits (66), Expect = 6.1
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 16/107 (14%)
Query: 199 SVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258
S+Q Y L +ED+ +Y R M++++QK L F R Y Y LE
Sbjct: 21 SIQEYELIHKEKEDE----NCLRKYRRQCMQDMHQK----LSFGPR-----YGFVYELET 67
Query: 259 GKQFL---EKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLK 302
GKQFL EK L++ ++ K S+L C +P +K
Sbjct: 68 GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVK 114
>gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor [Homo
sapiens]
Length = 1419
Score = 30.0 bits (66), Expect = 6.1
Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 25/163 (15%)
Query: 306 NPSFDGRLKDIDEDFKRELRNLVPLLLAPENLVEKEISGSKVTCRDL--VEYFKAYIKIY 363
+P D L ++ED R L VPLL AP++ E + KV D V K +++
Sbjct: 1081 DPDDDLTLLILEED--RLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEAL 1138
Query: 364 QGEELPHPKSMLQATAEANNLAAVAGARDTYCKSMEQVCG----GDKPYIAPSDLERK-- 417
G+E P + +VA DT K M G ++ + D E
Sbjct: 1139 CGQEEP------LLAFKGGKYVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSE 1192
Query: 418 ------HLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEE 454
D++E+ K+ +K+ + R Q++++A +E+
Sbjct: 1193 AEGSGGEDDIRELRAKKLALARKIAEQQ---RRQEKIQAVLED 1232
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 29.6 bits (65), Expect = 7.9
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 6/58 (10%)
Query: 402 CGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANF 459
C +I P D DL+++ K K GDE RR+ DQ ++E A F
Sbjct: 836 CDAVASWINPKD------DLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAF 887
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 29.6 bits (65), Expect = 7.9
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 6/58 (10%)
Query: 402 CGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEETYANF 459
C +I P D DL+++ K K GDE RR+ DQ ++E A F
Sbjct: 844 CDAVASWINPKD------DLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAF 895
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 29.6 bits (65), Expect = 7.9
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Query: 438 DEFCRRYQDQ--LEAEIEETYANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFI 495
D C+ YQ + ++ I + Y +F+ + ++ YA++ TLF F +Y++ + +
Sbjct: 690 DLHCKFYQLERLMQEYIPDLYNHFLDISLEAHM-YASQWFLTLFTAKFPLYMVFHIIDLL 748
Query: 496 GLNSIAVLCNLVMGL 510
I+V+ N+ +GL
Sbjct: 749 LCEGISVIFNVALGL 763
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,439,264
Number of Sequences: 37866
Number of extensions: 944154
Number of successful extensions: 2409
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2369
Number of HSP's gapped (non-prelim): 36
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.