Guide to the Human Genome
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Name: SMG6 Sequence: fasta or formatted (1419aa) NCBI GI: 115511020
Description:

Smg-6 homolog, nonsense mediated mRNA decay factor

Referenced in:

RNases and RNA Stability
Telomere Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.3         89           3
 C cysteine            1.4         20           2
 D aspartate           6.6         94           3
 E glutamate           8.7        124           4
 F phenylalanine       2.5         36           2
 G glycine             6.5         92           3
 H histidine           1.4         20           1
 I isoleucine          3.6         51           2
 K lysine              6.7         95           2
 L leucine            10.2        145           2
 M methionine          1.8         25           1
 N asparagine          3.9         55           2
 P proline             6.0         85           3
 Q glutamine           5.2         74           3
 R arginine            8.4        119           4
 S serine              7.9        112           2
 T threonine           4.1         58           2
 V valine              5.1         72           2
 W tryptophan          0.9         13           1
 Y tyrosine            2.8         40           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Smg-6 homolog, nonsense mediated mRNA decay factor ... 
SMG7                  0.027   SMG-7 homolog isoform 1 
SMG7                  0.027   SMG-7 homolog isoform 2 
SMG7                  0.024   SMG-7 homolog isoform 4 
SMG5                  0.018   SMG5 homolog nonsense mediated mRNA decay factor [H...
C1orf26               0.012   hypothetical protein LOC54823 
C1orf26               0.012   hypothetical protein LOC54823 
PPIG                  0.011   peptidylprolyl isomerase G 
HDGF2                 0.010   hepatoma-derived growth factor-related protein 2 iso...
HDGF2                 0.010   hepatoma-derived growth factor-related protein 2 iso...
PRPF38B               0.009   PRP38 pre-mRNA processing factor 38 (yeast) domain ...
THOC2                 0.009   THO complex 2 
LOC100286959          0.009   PREDICTED: hypothetical protein XP_002343921 
SUPT5H                0.009   suppressor of Ty 5 homolog isoform b 
SUPT5H                0.009   suppressor of Ty 5 homolog isoform a 
SUPT5H                0.009   suppressor of Ty 5 homolog isoform a 
SUPT5H                0.009   suppressor of Ty 5 homolog isoform a 
RPGR                  0.008   retinitis pigmentosa GTPase regulator isoform C [Hom...
RBM25                 0.008   RNA binding motif protein 25 
SFRS4                 0.008   splicing factor, arginine/serine-rich 4 
EPB41L2               0.008   erythrocyte membrane protein band 4.1-like 2 isofor...
EPB41L2               0.008   erythrocyte membrane protein band 4.1-like 2 isofor...
EPB41L2               0.008   erythrocyte membrane protein band 4.1-like 2 isoform ...
LOC100133599          0.007   PREDICTED: hypothetical protein 
SFRS12                0.007   splicing factor, arginine/serine-rich 12 isoform a ...
SFRS12                0.007   splicing factor, arginine/serine-rich 12 isoform b [...
ZNF469                0.007   zinc finger protein 469 
CALD1                 0.007   caldesmon 1 isoform 5 
MPHOSPH8              0.007   M-phase phosphoprotein 8 
ARID4B                0.007   AT rich interactive domain 4B isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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