BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|206597541 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] (540 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|206597541 solute carrier family 39 (metal ion transporter), m... 1093 0.0 gi|206597539 solute carrier family 39 (metal ion transporter), m... 1093 0.0 gi|187936949 solute carrier family 39 (zinc transporter), member... 235 9e-62 gi|55741750 solute carrier family 39 (zinc transporter), member ... 235 9e-62 gi|115430259 solute carrier family 39 (zinc transporter), member... 201 1e-51 gi|115430255 solute carrier family 39 (zinc transporter), member... 201 1e-51 gi|223633939 solute carrier family 39 (zinc transporter), member... 168 1e-41 gi|223633937 solute carrier family 39 (zinc transporter), member... 162 6e-40 gi|153252201 solute carrier family 39 (zinc transporter), member... 156 5e-38 gi|205830407 solute carrier family 39 (zinc transporter), member... 142 8e-34 gi|24586665 solute carrier family 39 (zinc transporter), member ... 141 1e-33 gi|205830403 solute carrier family 39 (zinc transporter), member... 141 1e-33 gi|153252214 solute carrier family 39 (zinc transporter), member... 139 9e-33 gi|205830405 solute carrier family 39 (zinc transporter), member... 139 9e-33 gi|190358541 solute carrier family 39 (zinc transporter), member... 137 2e-32 gi|205830424 solute carrier family 39 (zinc transporter), member... 136 6e-32 gi|190360568 solute carrier family 39 (zinc transporter), member... 136 6e-32 gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 130 4e-30 gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 130 4e-30 gi|205830426 solute carrier family 39 (zinc transporter), member... 129 9e-30 gi|190014617 solute carrier family 39 (zinc transporter), member... 105 1e-22 gi|40255101 solute carrier family 39 (zinc transporter), member ... 103 4e-22 gi|156415986 solute carrier family 39 (zinc transporter), member... 50 5e-06 gi|40254928 solute carrier family 39 (zinc transporter), member ... 45 1e-04 gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 44 5e-04 gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 44 5e-04 gi|58761544 amine oxidase (flavin containing) domain 2 isoform a... 38 0.021 gi|58761546 amine oxidase (flavin containing) domain 2 isoform b... 35 0.13 gi|21361423 solute carrier family 39 (zinc transporter), member ... 35 0.13 gi|123173757 RAVER1 [Homo sapiens] 35 0.13 >gi|206597541 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] Length = 540 Score = 1093 bits (2827), Expect = 0.0 Identities = 540/540 (100%), Positives = 540/540 (100%) Query: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR Sbjct: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60 Query: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL Sbjct: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120 Query: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ Sbjct: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180 Query: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR Sbjct: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240 Query: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV Sbjct: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300 Query: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ Sbjct: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360 Query: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420 Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480 Query: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG Sbjct: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540 >gi|206597539 solute carrier family 39 (metal ion transporter), member 5 [Homo sapiens] Length = 540 Score = 1093 bits (2827), Expect = 0.0 Identities = 540/540 (100%), Positives = 540/540 (100%) Query: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR Sbjct: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60 Query: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL Sbjct: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120 Query: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ Sbjct: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180 Query: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR Sbjct: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240 Query: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV Sbjct: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300 Query: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ Sbjct: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360 Query: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420 Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480 Query: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG Sbjct: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540 >gi|187936949 solute carrier family 39 (zinc transporter), member 10 [Homo sapiens] Length = 831 Score = 235 bits (599), Expect = 9e-62 Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%) Query: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168 L P G+L ++ APH+ S L D + DH +E CLN +QLL + Sbjct: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347 Query: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213 G +P++ F LCPALLYQIDSR+CI D+ SA Sbjct: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407 Query: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272 + +++ ++SL S L ++L+ ++ + LL FL ALAVGT+ GDALLHLLPH+Q G Sbjct: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467 Query: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313 +HA G L E D + GL LGG++LLF++E+ + + +H RG Sbjct: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527 Query: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353 + ++ R L L + + + L+PL + +G Sbjct: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587 Query: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375 Q+E KN +H A H G H H Sbjct: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647 Query: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421 H G +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF Sbjct: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707 Query: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481 CHELPHELGDFA+LL++G++ ++ ++ +L+S + G ++G + +T W+F VT Sbjct: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767 Query: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534 AG+FLYVALVDMLP +L P +LQ LGLL G +ML I L E++++ Sbjct: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826 Score = 42.7 bits (99), Expect = 8e-04 Identities = 20/37 (54%), Positives = 27/37 (72%) Query: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68 AE E+ +Y+ +LF YGENG L+ GL +LL +LGLG Sbjct: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92 >gi|55741750 solute carrier family 39 (zinc transporter), member 10 [Homo sapiens] Length = 831 Score = 235 bits (599), Expect = 9e-62 Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%) Query: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168 L P G+L ++ APH+ S L D + DH +E CLN +QLL + Sbjct: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347 Query: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213 G +P++ F LCPALLYQIDSR+CI D+ SA Sbjct: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407 Query: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272 + +++ ++SL S L ++L+ ++ + LL FL ALAVGT+ GDALLHLLPH+Q G Sbjct: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467 Query: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313 +HA G L E D + GL LGG++LLF++E+ + + +H RG Sbjct: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527 Query: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353 + ++ R L L + + + L+PL + +G Sbjct: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587 Query: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375 Q+E KN +H A H G H H Sbjct: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647 Query: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421 H G +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF Sbjct: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707 Query: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481 CHELPHELGDFA+LL++G++ ++ ++ +L+S + G ++G + +T W+F VT Sbjct: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767 Query: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534 AG+FLYVALVDMLP +L P +LQ LGLL G +ML I L E++++ Sbjct: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826 Score = 42.7 bits (99), Expect = 8e-04 Identities = 20/37 (54%), Positives = 27/37 (72%) Query: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68 AE E+ +Y+ +LF YGENG L+ GL +LL +LGLG Sbjct: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92 >gi|115430259 solute carrier family 39 (zinc transporter), member 4 isoform 1 [Homo sapiens] Length = 622 Score = 201 bits (512), Expect = 1e-51 Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%) Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214 CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L Sbjct: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 303 Query: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273 +LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P Sbjct: 304 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 363 Query: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330 GL + L++L GL+ F+ EN+ LL R L C + + Sbjct: 364 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 422 Query: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388 +G + L P + P+P +G R + ++ P L P + S + + +M+ Sbjct: 423 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 476 Query: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448 LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL Sbjct: 477 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 536 Query: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506 +L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P Sbjct: 537 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 593 Query: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531 LL +GLL G ++L ++L E+ Sbjct: 594 LLFLLHNVGLLGGWTVLLLLSLYED 618 >gi|115430255 solute carrier family 39 (zinc transporter), member 4 isoform 2 [Homo sapiens] Length = 647 Score = 201 bits (512), Expect = 1e-51 Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%) Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214 CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L Sbjct: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 328 Query: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273 +LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P Sbjct: 329 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 388 Query: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330 GL + L++L GL+ F+ EN+ LL R L C + + Sbjct: 389 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 447 Query: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388 +G + L P + P+P +G R + ++ P L P + S + + +M+ Sbjct: 448 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 501 Query: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448 LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL Sbjct: 502 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 561 Query: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506 +L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P Sbjct: 562 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 618 Query: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531 LL +GLL G ++L ++L E+ Sbjct: 619 LLFLLHNVGLLGGWTVLLLLSLYED 643 >gi|223633939 solute carrier family 39 (zinc transporter), member 12 isoform 1 [Homo sapiens] Length = 691 Score = 168 bits (425), Expect = 1e-41 Identities = 128/398 (32%), Positives = 191/398 (47%), Gaps = 34/398 (8%) Query: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211 ++ C + QL+ F + ++ F + P ++ Q+ S C A PP L Sbjct: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365 Query: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267 S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P Sbjct: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425 Query: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325 H QE G + + + ++GG+ F++E LL + P Sbjct: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPN--------- 472 Query: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH--GHQGGTD- 382 + + L NG L E Q R K++ +P Q G ++ Sbjct: 473 DKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNR 532 Query: 383 -------ITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAML 435 + M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+L Sbjct: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592 Query: 436 LQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495 L SGLS + +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP Sbjct: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLP 651 Query: 496 ALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERL 533 + P LLQ GL+LG +L + + E+ + Sbjct: 652 EMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689 >gi|223633937 solute carrier family 39 (zinc transporter), member 12 isoform 2 [Homo sapiens] Length = 654 Score = 162 bits (411), Expect = 6e-40 Identities = 125/388 (32%), Positives = 188/388 (48%), Gaps = 51/388 (13%) Query: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211 ++ C + QL+ F + ++ F + P ++ Q+ S C A PP L Sbjct: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365 Query: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267 S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P Sbjct: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425 Query: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325 H QE G + + + ++GG+ F++E LL + P + Sbjct: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475 Query: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDITW 385 PE+ QAA P G +++ A++ + Sbjct: 476 -----SPEDS--------QAAEMP--IGSMTASNRKCKAISL---------------LAI 505 Query: 386 MVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRL 445 M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+LL SGLS + Sbjct: 506 MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTA 565 Query: 446 LLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLP 505 +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP + P Sbjct: 566 ILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRP 624 Query: 506 TPHVLLQGLGLLLGGGLMLAITLLEERL 533 LLQ GL+LG +L + + E+ + Sbjct: 625 WMMFLLQNFGLILGWLSLLLLAIYEQNI 652 >gi|153252201 solute carrier family 39 (zinc transporter), member 6 isoform 1 [Homo sapiens] Length = 755 Score = 156 bits (394), Expect = 5e-38 Identities = 79/178 (44%), Positives = 116/178 (65%), Gaps = 13/178 (7%) Query: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420 H HSH + G + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV Sbjct: 573 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 632 Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480 FCHELPHELGDFA+LL++G++ ++ +L + +S L G G+ + ++ W+F + Sbjct: 633 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 692 Query: 481 TAGVFLYVALVDMLPALLRPPEP----LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534 TAG+F+YVALVDM+P +L + LQ G+LLG G+ML I++ E +++ Sbjct: 693 TAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIV 750 Score = 95.5 bits (236), Expect = 1e-19 Identities = 70/240 (29%), Positives = 113/240 (47%), Gaps = 33/240 (13%) Query: 156 EDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDL 209 ++C N S+LL + G+ PL +F LCPA++ QID+R C+ A P L Sbjct: 262 QECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL 321 Query: 210 LSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269 A + +A+ ++S S L ++L+ L+ + LL FL ALAVGTL GDA LHLLPH+ Sbjct: 322 QIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHS 381 Query: 270 QEGRHAGPGG---LPEKDLGP---------------------GLSVLGGLFLLFVLENML 305 H E GP GL+ LGGL+ +F++E++L Sbjct: 382 HASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVL 441 Query: 306 GLLRHRGLRPRCCRRKRRN---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362 L++ + + ++K N +E + + S ++ + + +G +SQ P Sbjct: 442 TLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 501 Score = 36.2 bits (82), Expect = 0.078 Identities = 15/48 (31%), Positives = 30/48 (62%) Query: 28 NLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRL 75 N+ A + ++L QLF YGEN +L+ G +LL ++G+ +++ + + Sbjct: 45 NVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHI 92 >gi|205830407 solute carrier family 39 (zinc transporter), member 8 isoform c [Homo sapiens] Length = 393 Score = 142 bits (358), Expect = 8e-34 Identities = 119/407 (29%), Positives = 179/407 (43%), Gaps = 54/407 (13%) Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212 H + CL ++ G S A +T +F+++CPA+L Q++ C P Sbjct: 2 HQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 61 Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272 L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A Sbjct: 62 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 119 Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323 G P+ D + ++V GG +LLF E ML +L H + + Sbjct: 120 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 174 Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367 + + L NG P A E G++E +S P L+ Sbjct: 175 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 232 Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427 G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH Sbjct: 233 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 280 Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487 ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY Sbjct: 281 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 338 Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528 ++L DM P +LR ++Q G+L G +L ITL Sbjct: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 385 >gi|24586665 solute carrier family 39 (zinc transporter), member 8 isoform a [Homo sapiens] Length = 460 Score = 141 bits (356), Expect = 1e-33 Identities = 120/407 (29%), Positives = 180/407 (44%), Gaps = 55/407 (13%) Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212 H N+ CL ++ G S A +T +F+++CPA+L Q++ C P Sbjct: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128 Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272 L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186 Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323 G P+ D + ++V GG +LLF E ML +L H + + Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241 Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367 + + L NG P A E G++E +S P L+ Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299 Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427 G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347 Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487 ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405 Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528 ++L DM P +LR ++Q G+L G +L ITL Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 452 >gi|205830403 solute carrier family 39 (zinc transporter), member 8 isoform a [Homo sapiens] Length = 460 Score = 141 bits (356), Expect = 1e-33 Identities = 120/407 (29%), Positives = 180/407 (44%), Gaps = 55/407 (13%) Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212 H N+ CL ++ G S A +T +F+++CPA+L Q++ C P Sbjct: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128 Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272 L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186 Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323 G P+ D + ++V GG +LLF E ML +L H + + Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241 Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367 + + L NG P A E G++E +S P L+ Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299 Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427 G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347 Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487 ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405 Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528 ++L DM P +LR ++Q G+L G +L ITL Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 452 >gi|153252214 solute carrier family 39 (zinc transporter), member 6 isoform 2 [Homo sapiens] Length = 433 Score = 139 bits (349), Expect = 9e-33 Identities = 66/134 (49%), Positives = 94/134 (70%), Gaps = 9/134 (6%) Query: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420 H HSH + G + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV Sbjct: 298 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 357 Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480 FCHELPHELGDFA+LL++G++ ++ +L + +S L G G+ + ++ W+F + Sbjct: 358 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 417 Query: 481 TAGVFLYVALVDML 494 TAG+F+YVALVDM+ Sbjct: 418 TAGLFMYVALVDMV 431 Score = 81.6 bits (200), Expect = 2e-15 Identities = 64/221 (28%), Positives = 102/221 (46%), Gaps = 33/221 (14%) Query: 175 PLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDLLSALLQSALAVLLLSLPSP 228 PL +F LCPA++ QID+R C+ A P L A + +A+ ++S S Sbjct: 6 PLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSL 65 Query: 229 LSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGG---LPEKDL 285 L ++L+ L+ + LL FL ALAVGTL GDA LHLLPH+ H E Sbjct: 66 LGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKR 125 Query: 286 GP---------------------GLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRN 324 GP GL+ LGGL+ +F++E++L L++ + + ++K N Sbjct: 126 GPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPEN 185 Query: 325 ---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362 +E + + S ++ + + +G +SQ P Sbjct: 186 DDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 226 >gi|205830405 solute carrier family 39 (zinc transporter), member 8 isoform b [Homo sapiens] Length = 444 Score = 139 bits (349), Expect = 9e-33 Identities = 110/370 (29%), Positives = 166/370 (44%), Gaps = 49/370 (13%) Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212 H N+ CL ++ G S A +T +F+++CPA+L Q++ C P Sbjct: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128 Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272 L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186 Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323 G P+ D + ++V GG +LLF E ML +L H + + Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241 Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367 + + L NG P A E G++E +S P L+ Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299 Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427 G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347 Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487 ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405 Query: 488 VALVDMLPAL 497 ++L DM P + Sbjct: 406 ISLADMFPEM 415 >gi|190358541 solute carrier family 39 (zinc transporter), member 14 isoform b [Homo sapiens] Length = 492 Score = 137 bits (346), Expect = 2e-32 Identities = 111/404 (27%), Positives = 173/404 (42%), Gaps = 43/404 (10%) Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217 C + L S + + + CP +L Q+DSR C + SA Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150 Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269 L+V L++L S L +L+L +L + AL++GTL +AL L+P A Sbjct: 151 VEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEA 210 Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313 G L + + V GG +L F E +L +L H G Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265 Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370 + K +N + ++ P++ S E G A Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325 Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430 +G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383 Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490 DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441 Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528 DM P + + + P + +Q LGLL G +M+ +T+ Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484 >gi|205830424 solute carrier family 39 (zinc transporter), member 14 isoform a [Homo sapiens] Length = 492 Score = 136 bits (342), Expect = 6e-32 Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%) Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217 C + L S + + + CP +L Q+DSR C + SA Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150 Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269 L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210 Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313 G L + + V GG +L F E +L +L H G Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265 Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370 + K +N + ++ P++ S E G A Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325 Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430 +G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383 Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490 DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441 Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528 DM P + + + P + +Q LGLL G +M+ +T+ Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484 >gi|190360568 solute carrier family 39 (zinc transporter), member 14 isoform a [Homo sapiens] Length = 492 Score = 136 bits (342), Expect = 6e-32 Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%) Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217 C + L S + + + CP +L Q+DSR C + SA Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150 Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269 L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210 Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313 G L + + V GG +L F E +L +L H G Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265 Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370 + K +N + ++ P++ S E G A Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325 Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430 +G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383 Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490 DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441 Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528 DM P + + + P + +Q LGLL G +M+ +T+ Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484 >gi|117553619 solute carrier family 39, member 7 [Homo sapiens] Length = 469 Score = 130 bits (326), Expect = 4e-30 Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%) Query: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257 AP DL + L + AL +L +P +L L + PR R LL L + A G L Sbjct: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180 Query: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304 GDA LHL+PHA E H+G G + L GL VL G+ V+E Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236 Query: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360 + RH +G + TR + + Q++ E + Q+ + Sbjct: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293 Query: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417 P P Q ++ + G D+ ++ L D HN TDGLAIGA+F G G+ TT Sbjct: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352 Query: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470 + V HE+PHE+GDFA+L+QSG S + RL LL+ V G A+L VG + Sbjct: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412 Query: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530 WV TAG F+YVA V +LP LLR PL + LL+ LGLL G +M+ I LE Sbjct: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469 >gi|117553608 solute carrier family 39, member 7 [Homo sapiens] Length = 469 Score = 130 bits (326), Expect = 4e-30 Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%) Query: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257 AP DL + L + AL +L +P +L L + PR R LL L + A G L Sbjct: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180 Query: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304 GDA LHL+PHA E H+G G + L GL VL G+ V+E Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236 Query: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360 + RH +G + TR + + Q++ E + Q+ + Sbjct: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293 Query: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417 P P Q ++ + G D+ ++ L D HN TDGLAIGA+F G G+ TT Sbjct: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352 Query: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470 + V HE+PHE+GDFA+L+QSG S + RL LL+ V G A+L VG + Sbjct: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412 Query: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530 WV TAG F+YVA V +LP LLR PL + LL+ LGLL G +M+ I LE Sbjct: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469 >gi|205830426 solute carrier family 39 (zinc transporter), member 14 isoform c [Homo sapiens] Length = 481 Score = 129 bits (323), Expect = 9e-30 Identities = 101/364 (27%), Positives = 154/364 (42%), Gaps = 36/364 (9%) Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217 C + L S + + + CP +L Q+DSR C + SA Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150 Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269 L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210 Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313 G L + + V GG +L F E +L +L H G Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265 Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370 + K +N + ++ P++ S E G A Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325 Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430 +G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383 Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490 DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441 Query: 491 VDML 494 DM+ Sbjct: 442 ADMM 445 >gi|190014617 solute carrier family 39 (zinc transporter), member 13 isoform a [Homo sapiens] Length = 371 Score = 105 bits (262), Expect = 1e-22 Identities = 103/332 (31%), Positives = 147/332 (44%), Gaps = 52/332 (15%) Query: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267 LL +L+ V LL +P + +L G L+ LL F A+G L G+ LHLLP Sbjct: 72 LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127 Query: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323 A A PGG + + GL V+ G+ LE M + G Sbjct: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178 Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383 + N DP + AL +P A+ P L G+ Sbjct: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219 Query: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440 + LL + + N T GLA+ A+F GL TT+A+ HE+PHE+GDFA+LL++G Sbjct: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277 Query: 441 SFRRLLLLSLVSGALGLGGAVLG------VGLSLGPVPLTPWVFGVTAGVFLYVALVDML 494 S +L L + + G LG G A+ VG S WV T+G FLY+ALV++L Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVL 337 Query: 495 PALLRPPEPLPTPHVLLQGLGLLLGGGLMLAI 526 P LL +P + LQ L LL G +++ + Sbjct: 338 PDLLEEEDPWRS----LQQLLLLCAGIVVMVL 365 >gi|40255101 solute carrier family 39 (zinc transporter), member 13 isoform b [Homo sapiens] Length = 364 Score = 103 bits (257), Expect = 4e-22 Identities = 101/326 (30%), Positives = 145/326 (44%), Gaps = 47/326 (14%) Query: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267 LL +L+ V LL +P + +L G L+ LL F A+G L G+ LHLLP Sbjct: 72 LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127 Query: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323 A A PGG + + GL V+ G+ LE M + G Sbjct: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178 Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383 + N DP + AL +P A+ P L G+ Sbjct: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219 Query: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440 + LL + + N T GLA+ A+F GL TT+A+ HE+PHE+GDFA+LL++G Sbjct: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277 Query: 441 SFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRP 500 S +L L + + G LG G A+ G WV T+G FLY+ALV++LP LL Sbjct: 278 SAAKLQLSTALGGLLGAGFAIC-TQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEE 336 Query: 501 PEPLPTPHVLLQGLGLLLGGGLMLAI 526 +P + LQ L LL G +++ + Sbjct: 337 EDPWRS----LQQLLLLCAGIVVMVL 358 >gi|156415986 solute carrier family 39 (zinc transporter), member 2 [Homo sapiens] Length = 309 Score = 50.1 bits (118), Expect = 5e-06 Identities = 50/140 (35%), Positives = 68/140 (48%), Gaps = 13/140 (9%) Query: 373 HSHGH----QGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHE 428 HSHGH G ++LL H++ +GLA+G ++ + LAV H+ Sbjct: 150 HSHGHLPSPSKGPLRALVLLLSLSFHSVFEGLAVG--LQPTVAATVQLCLAVLAHKGLVV 207 Query: 429 LGDFAMLLQSGLSFR----RLLLLSLVSG-ALGLGGAVLGVGLSLGPVPLTPWVF-GVTA 482 G L+ G S R +LLL+L+S L +G AV G G S G L V GV A Sbjct: 208 FGVGMRLVHLGTSSRWAVFSILLLALMSPLGLAVGLAVTG-GDSEGGRGLAQAVLEGVAA 266 Query: 483 GVFLYVALVDMLPALLRPPE 502 G FLYV +++LP L PE Sbjct: 267 GTFLYVTFLEILPRELASPE 286 >gi|40254928 solute carrier family 39 (zinc transporter), member 9 [Homo sapiens] Length = 307 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 14/118 (11%) Query: 389 LGDGLHNLTDGLAIGAAFSDGFSS-GLSTTLAVFCHELPHELGDFAMLLQSGLSFRR--- 444 LG +H DG+A+GAA S +S L +A+ H+ P G + L+ +GL R Sbjct: 150 LGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRK 209 Query: 445 -LLLLSLVSGALGLGGAVLGVGLS------LGPVPLTPWVFGVTAGVFLYVALVDMLP 495 LL+ +L + + + V +GLS L V T +AG FLYVA V +LP Sbjct: 210 HLLVFALAAPVMSM---VTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLP 264 >gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo sapiens] Length = 342 Score = 43.5 bits (101), Expect = 5e-04 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%) Query: 386 MVLLGDGLHNLTDGLAIGAAF-------SDGFSSGLSTTLAVFCHELPHELGDFAMLLQS 438 +++L +HN+ +GLA+G F S F S + + + P L L + Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255 Query: 439 GLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495 G S R +SG + V G + P+ P+ AG +YV + D++P Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 312 >gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo sapiens] Length = 335 Score = 43.5 bits (101), Expect = 5e-04 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%) Query: 386 MVLLGDGLHNLTDGLAIGAAF-------SDGFSSGLSTTLAVFCHELPHELGDFAMLLQS 438 +++L +HN+ +GLA+G F S F S + + + P L L + Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248 Query: 439 GLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495 G S R +SG + V G + P+ P+ AG +YV + D++P Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 305 >gi|58761544 amine oxidase (flavin containing) domain 2 isoform a [Homo sapiens] Length = 876 Score = 38.1 bits (87), Expect = 0.021 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 15/113 (13%) Query: 316 RCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH 375 R RRKR +E R +D E+ + ++ + E A+ ++EK PP APP + S Sbjct: 109 RTSRRKRAKVEYREMD-ESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESE 167 Query: 376 GHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHE 428 + GL + + G + DG +SG+ A F LPH+ Sbjct: 168 PEEPSGQ-------AGGLQDDSSG-----GYGDGQASGVEG--AAFQSRLPHD 206 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 333 ENGSGMALQPL----QAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQG 379 ENGS +A QP A PGA G+R + PP +PPG G G Sbjct: 32 ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAG 82 >gi|58761546 amine oxidase (flavin containing) domain 2 isoform b [Homo sapiens] Length = 852 Score = 35.4 bits (80), Expect = 0.13 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 333 ENGSGMALQPL----QAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQG 379 ENGS +A QP A PGA G+R + PP +PPG G G Sbjct: 32 ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAG 82 Score = 33.9 bits (76), Expect = 0.39 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Query: 316 RCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHS 374 R RRKR +E R +D E+ + ++ + E A+ ++EK PP APP + S Sbjct: 109 RTSRRKRAKVEYREMD-ESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENES 166 >gi|21361423 solute carrier family 39 (zinc transporter), member 1 [Homo sapiens] Length = 324 Score = 35.4 bits (80), Expect = 0.13 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Query: 393 LHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVS 452 LH++ +GLA+G + + LA+ H+ + LLQS L + + ++ Sbjct: 189 LHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILF 246 Query: 453 GALGLGGAVLGVGLSLGPVPLTPW----VFGVTAGVFLYVALVDMLPALLRPPEP-LPTP 507 + G LG L+ PL + G+ AG FLY+ +++LP L E + Sbjct: 247 SCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKV 306 Query: 508 HVLLQGLGLLLG 519 +LL G LL G Sbjct: 307 ILLLAGFALLTG 318 >gi|123173757 RAVER1 [Homo sapiens] Length = 756 Score = 35.4 bits (80), Expect = 0.13 Identities = 63/192 (32%), Positives = 66/192 (34%), Gaps = 49/192 (25%) Query: 202 APAPPGDLLSALLQSALAVLLLS----LPSPLSLLLLRLLGPR-----LLRPLL------ 246 AP PPG + A L +A A L LP P L LL LGP LL PLL Sbjct: 315 APGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGG 374 Query: 247 --GFLGA-----LAVGTLCGDALLHLLPHAQEGRHAG-PGGLPEKDLGPGLSVLGGLFLL 298 G LGA L G ALL L Q + G G P L PG L Sbjct: 375 KQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPL--- 431 Query: 299 FVLENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKN 358 LG L G P L P G L P P A G RE Sbjct: 432 ------LGELPAGGGLP------------PELPPRRGKPPPLLPSVLGP---AGGDREAL 470 Query: 359 SQHPPA--LAPP 368 PPA L PP Sbjct: 471 GLGPPAAQLTPP 482 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.143 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,546,861 Number of Sequences: 37866 Number of extensions: 1464179 Number of successful extensions: 5275 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 55 Number of HSP's that attempted gapping in prelim test: 5085 Number of HSP's gapped (non-prelim): 192 length of query: 540 length of database: 18,247,518 effective HSP length: 107 effective length of query: 433 effective length of database: 14,195,856 effective search space: 6146805648 effective search space used: 6146805648 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.