Guide to the Human Genome
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Search of human proteins with 206597541

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|206597541 solute carrier family 39 (metal ion transporter), m...  1093   0.0  
gi|206597539 solute carrier family 39 (metal ion transporter), m...  1093   0.0  
gi|187936949 solute carrier family 39 (zinc transporter), member...   235   9e-62
gi|55741750 solute carrier family 39 (zinc transporter), member ...   235   9e-62
gi|115430259 solute carrier family 39 (zinc transporter), member...   201   1e-51
gi|115430255 solute carrier family 39 (zinc transporter), member...   201   1e-51
gi|223633939 solute carrier family 39 (zinc transporter), member...   168   1e-41
gi|223633937 solute carrier family 39 (zinc transporter), member...   162   6e-40
gi|153252201 solute carrier family 39 (zinc transporter), member...   156   5e-38
gi|205830407 solute carrier family 39 (zinc transporter), member...   142   8e-34
gi|24586665 solute carrier family 39 (zinc transporter), member ...   141   1e-33
gi|205830403 solute carrier family 39 (zinc transporter), member...   141   1e-33
gi|153252214 solute carrier family 39 (zinc transporter), member...   139   9e-33
gi|205830405 solute carrier family 39 (zinc transporter), member...   139   9e-33
gi|190358541 solute carrier family 39 (zinc transporter), member...   137   2e-32
gi|205830424 solute carrier family 39 (zinc transporter), member...   136   6e-32
gi|190360568 solute carrier family 39 (zinc transporter), member...   136   6e-32
gi|117553619 solute carrier family 39, member 7 [Homo sapiens]        130   4e-30
gi|117553608 solute carrier family 39, member 7 [Homo sapiens]        130   4e-30
gi|205830426 solute carrier family 39 (zinc transporter), member...   129   9e-30
gi|190014617 solute carrier family 39 (zinc transporter), member...   105   1e-22
gi|40255101 solute carrier family 39 (zinc transporter), member ...   103   4e-22
gi|156415986 solute carrier family 39 (zinc transporter), member...    50   5e-06
gi|40254928 solute carrier family 39 (zinc transporter), member ...    45   1e-04
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo...    44   5e-04
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo...    44   5e-04
gi|58761544 amine oxidase (flavin containing) domain 2 isoform a...    38   0.021
gi|58761546 amine oxidase (flavin containing) domain 2 isoform b...    35   0.13 
gi|21361423 solute carrier family 39 (zinc transporter), member ...    35   0.13 
gi|123173757 RAVER1 [Homo sapiens]                                     35   0.13 

>gi|206597541 solute carrier family 39 (metal ion transporter),
           member 5 [Homo sapiens]
          Length = 540

 Score = 1093 bits (2827), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60
           MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR
Sbjct: 1   MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60

Query: 61  LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120
           LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL
Sbjct: 61  LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120

Query: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180
           EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ
Sbjct: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180

Query: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240
           FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR
Sbjct: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240

Query: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300
           LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV
Sbjct: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300

Query: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360
           LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ
Sbjct: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360

Query: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
           HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420

Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
           FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV
Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480

Query: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540
           TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG
Sbjct: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540


>gi|206597539 solute carrier family 39 (metal ion transporter),
           member 5 [Homo sapiens]
          Length = 540

 Score = 1093 bits (2827), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60
           MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR
Sbjct: 1   MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60

Query: 61  LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120
           LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL
Sbjct: 61  LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120

Query: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180
           EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ
Sbjct: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180

Query: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240
           FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR
Sbjct: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240

Query: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300
           LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV
Sbjct: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300

Query: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360
           LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ
Sbjct: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360

Query: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
           HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420

Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
           FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV
Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480

Query: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540
           TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG
Sbjct: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540


>gi|187936949 solute carrier family 39 (zinc transporter), member 10
           [Homo sapiens]
          Length = 831

 Score =  235 bits (599), Expect = 9e-62
 Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%)

Query: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168
           L P   G+L  ++   APH+      S        L  D +  DH +E CLN +QLL  +
Sbjct: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347

Query: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213
           G    +P++   F  LCPALLYQIDSR+CI         D+                SA 
Sbjct: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407

Query: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272
           +   +++ ++SL S L ++L+ ++     + LL FL ALAVGT+ GDALLHLLPH+Q G 
Sbjct: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467

Query: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313
               +HA   G          L E D +  GL  LGG++LLF++E+ + + +H    RG 
Sbjct: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527

Query: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353
           +    ++        R L    L +  +   + L+PL    +                +G
Sbjct: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587

Query: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375
           Q+E   KN                      +H    A   H G              H H
Sbjct: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647

Query: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421
            H               G  +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF
Sbjct: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707

Query: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481
           CHELPHELGDFA+LL++G++ ++ ++ +L+S  +   G ++G  +      +T W+F VT
Sbjct: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767

Query: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
           AG+FLYVALVDMLP +L            P    +LQ LGLL G  +ML I L E++++
Sbjct: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 20/37 (54%), Positives = 27/37 (72%)

Query: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68
          AE E+ +Y+ +LF  YGENG L+  GL +LL +LGLG
Sbjct: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92


>gi|55741750 solute carrier family 39 (zinc transporter), member 10
           [Homo sapiens]
          Length = 831

 Score =  235 bits (599), Expect = 9e-62
 Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%)

Query: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168
           L P   G+L  ++   APH+      S        L  D +  DH +E CLN +QLL  +
Sbjct: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347

Query: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213
           G    +P++   F  LCPALLYQIDSR+CI         D+                SA 
Sbjct: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407

Query: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272
           +   +++ ++SL S L ++L+ ++     + LL FL ALAVGT+ GDALLHLLPH+Q G 
Sbjct: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467

Query: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313
               +HA   G          L E D +  GL  LGG++LLF++E+ + + +H    RG 
Sbjct: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527

Query: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353
           +    ++        R L    L +  +   + L+PL    +                +G
Sbjct: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587

Query: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375
           Q+E   KN                      +H    A   H G              H H
Sbjct: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647

Query: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421
            H               G  +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF
Sbjct: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707

Query: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481
           CHELPHELGDFA+LL++G++ ++ ++ +L+S  +   G ++G  +      +T W+F VT
Sbjct: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767

Query: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
           AG+FLYVALVDMLP +L            P    +LQ LGLL G  +ML I L E++++
Sbjct: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 20/37 (54%), Positives = 27/37 (72%)

Query: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68
          AE E+ +Y+ +LF  YGENG L+  GL +LL +LGLG
Sbjct: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92


>gi|115430259 solute carrier family 39 (zinc transporter), member 4
           isoform 1 [Homo sapiens]
          Length = 622

 Score =  201 bits (512), Expect = 1e-51
 Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)

Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
           CL+   ++  +GLS  A +TP  +A L PALL Q  S  C     P P  D LS     L
Sbjct: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 303

Query: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
             +LA LL+ L +   LLLL   G R +   +L    +LAVG L GDA+LHL P      
Sbjct: 304 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 363

Query: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
                GL  +     L++L GL+  F+ EN+  LL  R    L    C     +    + 
Sbjct: 364 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 422

Query: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
              +G  + L P +   P+P  +G R +  ++  P L  P  +  S   +    + +M+ 
Sbjct: 423 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 476

Query: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
           LGD +HN  DGLA+GAAF+  + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 477 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 536

Query: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
           +L S      G    L VG+S        W+  V  G+FLYVAL DMLPA+L+  +P P 
Sbjct: 537 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 593

Query: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
              LL  +GLL G  ++L ++L E+
Sbjct: 594 LLFLLHNVGLLGGWTVLLLLSLYED 618


>gi|115430255 solute carrier family 39 (zinc transporter), member 4
           isoform 2 [Homo sapiens]
          Length = 647

 Score =  201 bits (512), Expect = 1e-51
 Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)

Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
           CL+   ++  +GLS  A +TP  +A L PALL Q  S  C     P P  D LS     L
Sbjct: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 328

Query: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
             +LA LL+ L +   LLLL   G R +   +L    +LAVG L GDA+LHL P      
Sbjct: 329 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 388

Query: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
                GL  +     L++L GL+  F+ EN+  LL  R    L    C     +    + 
Sbjct: 389 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 447

Query: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
              +G  + L P +   P+P  +G R +  ++  P L  P  +  S   +    + +M+ 
Sbjct: 448 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 501

Query: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
           LGD +HN  DGLA+GAAF+  + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 502 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 561

Query: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
           +L S      G    L VG+S        W+  V  G+FLYVAL DMLPA+L+  +P P 
Sbjct: 562 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 618

Query: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
              LL  +GLL G  ++L ++L E+
Sbjct: 619 LLFLLHNVGLLGGWTVLLLLSLYED 643


>gi|223633939 solute carrier family 39 (zinc transporter), member 12
           isoform 1 [Homo sapiens]
          Length = 691

 Score =  168 bits (425), Expect = 1e-41
 Identities = 128/398 (32%), Positives = 191/398 (47%), Gaps = 34/398 (8%)

Query: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
           ++ C +  QL+  F     + ++   F  + P ++ Q+ S  C       A  PP   L 
Sbjct: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365

Query: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
               S +AV LL+L S L   L+         R +L     LAVGTL GDALLHL+P   
Sbjct: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425

Query: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
             H QE    G     +  +   + ++GG+   F++E    LL    + P          
Sbjct: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPN--------- 472

Query: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH--GHQGGTD- 382
           + + L   NG       L    E   Q  R K++      +P   Q      G    ++ 
Sbjct: 473 DKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNR 532

Query: 383 -------ITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAML 435
                  +  M+L+GD LHN  DGLAIGAAFS    SG++TT+A+ CHE+PHE+GDFA+L
Sbjct: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592

Query: 436 LQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
           L SGLS +  +L++ +S      G  +G+ +S  P  +  W+F VTAG+FLY++LV+MLP
Sbjct: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLP 651

Query: 496 ALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERL 533
            +       P    LLQ  GL+LG   +L + + E+ +
Sbjct: 652 EMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689


>gi|223633937 solute carrier family 39 (zinc transporter), member 12
           isoform 2 [Homo sapiens]
          Length = 654

 Score =  162 bits (411), Expect = 6e-40
 Identities = 125/388 (32%), Positives = 188/388 (48%), Gaps = 51/388 (13%)

Query: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
           ++ C +  QL+  F     + ++   F  + P ++ Q+ S  C       A  PP   L 
Sbjct: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365

Query: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
               S +AV LL+L S L   L+         R +L     LAVGTL GDALLHL+P   
Sbjct: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425

Query: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
             H QE    G     +  +   + ++GG+   F++E    LL    + P   +      
Sbjct: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475

Query: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDITW 385
                 PE+         QAA  P   G    +++   A++                +  
Sbjct: 476 -----SPEDS--------QAAEMP--IGSMTASNRKCKAISL---------------LAI 505

Query: 386 MVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRL 445
           M+L+GD LHN  DGLAIGAAFS    SG++TT+A+ CHE+PHE+GDFA+LL SGLS +  
Sbjct: 506 MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTA 565

Query: 446 LLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLP 505
           +L++ +S      G  +G+ +S  P  +  W+F VTAG+FLY++LV+MLP +       P
Sbjct: 566 ILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRP 624

Query: 506 TPHVLLQGLGLLLGGGLMLAITLLEERL 533
               LLQ  GL+LG   +L + + E+ +
Sbjct: 625 WMMFLLQNFGLILGWLSLLLLAIYEQNI 652


>gi|153252201 solute carrier family 39 (zinc transporter), member 6
           isoform 1 [Homo sapiens]
          Length = 755

 Score =  156 bits (394), Expect = 5e-38
 Identities = 79/178 (44%), Positives = 116/178 (65%), Gaps = 13/178 (7%)

Query: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
           H  HSH  +         G   + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV
Sbjct: 573 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 632

Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
           FCHELPHELGDFA+LL++G++ ++ +L + +S  L   G   G+ +      ++ W+F +
Sbjct: 633 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 692

Query: 481 TAGVFLYVALVDMLPALLRPPEP----LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
           TAG+F+YVALVDM+P +L             +  LQ  G+LLG G+ML I++ E +++
Sbjct: 693 TAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIV 750



 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 70/240 (29%), Positives = 113/240 (47%), Gaps = 33/240 (13%)

Query: 156 EDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDL 209
           ++C N S+LL + G+    PL   +F  LCPA++ QID+R C+       A  P     L
Sbjct: 262 QECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL 321

Query: 210 LSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
             A +   +A+ ++S  S L ++L+ L+     + LL FL ALAVGTL GDA LHLLPH+
Sbjct: 322 QIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHS 381

Query: 270 QEGRHAGPGG---LPEKDLGP---------------------GLSVLGGLFLLFVLENML 305
               H          E   GP                     GL+ LGGL+ +F++E++L
Sbjct: 382 HASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVL 441

Query: 306 GLLRHRGLRPRCCRRKRRN---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362
            L++    + +  ++K  N   +E +    +  S ++    +   +   +G    +SQ P
Sbjct: 442 TLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 501



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 15/48 (31%), Positives = 30/48 (62%)

Query: 28 NLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRL 75
          N+  A   + ++L QLF  YGEN +L+  G  +LL ++G+ +++ + +
Sbjct: 45 NVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHI 92


>gi|205830407 solute carrier family 39 (zinc transporter), member 8
           isoform c [Homo sapiens]
          Length = 393

 Score =  142 bits (358), Expect = 8e-34
 Identities = 119/407 (29%), Positives = 179/407 (43%), Gaps = 54/407 (13%)

Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
           H +  CL   ++    G S A  +T  +F+++CPA+L Q++   C   P           
Sbjct: 2   HQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 61

Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
                L+V +++L S L L+L  L+       +L F   LA+GTL  +A+  L+P A   
Sbjct: 62  WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 119

Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
                G  P+ D  +   ++V GG +LLF  E ML +L        H          + +
Sbjct: 120 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 174

Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
             + + L   NG      P  A  E                 G++E +S      P L+ 
Sbjct: 175 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 232

Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
            G             I WM+ L D LHN  DGLAIGA+ +     GLST++A+ C E PH
Sbjct: 233 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 280

Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
           ELGDF +LL +G+S R+ LL + +S      G   G+ +     P    +F +  G+FLY
Sbjct: 281 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 338

Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
           ++L DM P    +LR             ++Q  G+L G   +L ITL
Sbjct: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 385


>gi|24586665 solute carrier family 39 (zinc transporter), member 8
           isoform a [Homo sapiens]
          Length = 460

 Score =  141 bits (356), Expect = 1e-33
 Identities = 120/407 (29%), Positives = 180/407 (44%), Gaps = 55/407 (13%)

Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
           H N+ CL   ++    G S A  +T  +F+++CPA+L Q++   C   P           
Sbjct: 70  HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128

Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
                L+V +++L S L L+L  L+       +L F   LA+GTL  +A+  L+P A   
Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186

Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
                G  P+ D  +   ++V GG +LLF  E ML +L        H          + +
Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241

Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
             + + L   NG      P  A  E                 G++E +S      P L+ 
Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299

Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
            G             I WM+ L D LHN  DGLAIGA+ +     GLST++A+ C E PH
Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347

Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
           ELGDF +LL +G+S R+ LL + +S      G   G+ +     P    +F +  G+FLY
Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405

Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
           ++L DM P    +LR             ++Q  G+L G   +L ITL
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 452


>gi|205830403 solute carrier family 39 (zinc transporter), member 8
           isoform a [Homo sapiens]
          Length = 460

 Score =  141 bits (356), Expect = 1e-33
 Identities = 120/407 (29%), Positives = 180/407 (44%), Gaps = 55/407 (13%)

Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
           H N+ CL   ++    G S A  +T  +F+++CPA+L Q++   C   P           
Sbjct: 70  HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128

Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
                L+V +++L S L L+L  L+       +L F   LA+GTL  +A+  L+P A   
Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186

Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
                G  P+ D  +   ++V GG +LLF  E ML +L        H          + +
Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241

Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
             + + L   NG      P  A  E                 G++E +S      P L+ 
Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299

Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
            G             I WM+ L D LHN  DGLAIGA+ +     GLST++A+ C E PH
Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347

Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
           ELGDF +LL +G+S R+ LL + +S      G   G+ +     P    +F +  G+FLY
Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405

Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
           ++L DM P    +LR             ++Q  G+L G   +L ITL
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 452


>gi|153252214 solute carrier family 39 (zinc transporter), member 6
           isoform 2 [Homo sapiens]
          Length = 433

 Score =  139 bits (349), Expect = 9e-33
 Identities = 66/134 (49%), Positives = 94/134 (70%), Gaps = 9/134 (6%)

Query: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
           H  HSH  +         G   + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV
Sbjct: 298 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 357

Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
           FCHELPHELGDFA+LL++G++ ++ +L + +S  L   G   G+ +      ++ W+F +
Sbjct: 358 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 417

Query: 481 TAGVFLYVALVDML 494
           TAG+F+YVALVDM+
Sbjct: 418 TAGLFMYVALVDMV 431



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 64/221 (28%), Positives = 102/221 (46%), Gaps = 33/221 (14%)

Query: 175 PLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDLLSALLQSALAVLLLSLPSP 228
           PL   +F  LCPA++ QID+R C+       A  P     L  A +   +A+ ++S  S 
Sbjct: 6   PLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSL 65

Query: 229 LSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGG---LPEKDL 285
           L ++L+ L+     + LL FL ALAVGTL GDA LHLLPH+    H          E   
Sbjct: 66  LGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKR 125

Query: 286 GP---------------------GLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRN 324
           GP                     GL+ LGGL+ +F++E++L L++    + +  ++K  N
Sbjct: 126 GPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPEN 185

Query: 325 ---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362
              +E +    +  S ++    +   +   +G    +SQ P
Sbjct: 186 DDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 226


>gi|205830405 solute carrier family 39 (zinc transporter), member 8
           isoform b [Homo sapiens]
          Length = 444

 Score =  139 bits (349), Expect = 9e-33
 Identities = 110/370 (29%), Positives = 166/370 (44%), Gaps = 49/370 (13%)

Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
           H N+ CL   ++    G S A  +T  +F+++CPA+L Q++   C   P           
Sbjct: 70  HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128

Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
                L+V +++L S L L+L  L+       +L F   LA+GTL  +A+  L+P A   
Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186

Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
                G  P+ D  +   ++V GG +LLF  E ML +L        H          + +
Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241

Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
             + + L   NG      P  A  E                 G++E +S      P L+ 
Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299

Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
            G             I WM+ L D LHN  DGLAIGA+ +     GLST++A+ C E PH
Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347

Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
           ELGDF +LL +G+S R+ LL + +S      G   G+ +     P    +F +  G+FLY
Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405

Query: 488 VALVDMLPAL 497
           ++L DM P +
Sbjct: 406 ISLADMFPEM 415


>gi|190358541 solute carrier family 39 (zinc transporter), member 14
           isoform b [Homo sapiens]
          Length = 492

 Score =  137 bits (346), Expect = 2e-32
 Identities = 111/404 (27%), Positives = 173/404 (42%), Gaps = 43/404 (10%)

Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
           C +   L      S  + +   +    CP +L Q+DSR C          +       SA
Sbjct: 91  CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150

Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
                   L+V L++L S L +L+L          +L +  AL++GTL  +AL  L+P A
Sbjct: 151 VEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEA 210

Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
                 G   L +  +     V GG +L F  E +L +L       H G           
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265

Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
              +      K +N +  ++ P++ S           E    G            A    
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325

Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
           +G  +   G   + WM+ L DGLHN  DGLAIGA+F+     G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383

Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
           DF +LL +G+S ++ L  + +S      G  L  G+  G      W+F +  G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441

Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
            DM P +    +       +  P + +Q LGLL G  +M+ +T+
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484


>gi|205830424 solute carrier family 39 (zinc transporter), member 14
           isoform a [Homo sapiens]
          Length = 492

 Score =  136 bits (342), Expect = 6e-32
 Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%)

Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
           C +   L      S  + +   +    CP +L Q+DSR C          +       SA
Sbjct: 91  CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150

Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
                   L V ++SL S L   ++  +     + LL +  ALA+GTL  +AL  L+P A
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210

Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
                 G   L +  +     V GG +L F  E +L +L       H G           
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265

Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
              +      K +N +  ++ P++ S           E    G            A    
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325

Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
           +G  +   G   + WM+ L DGLHN  DGLAIGA+F+     G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383

Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
           DF +LL +G+S ++ L  + +S      G  L  G+  G      W+F +  G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441

Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
            DM P +    +       +  P + +Q LGLL G  +M+ +T+
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484


>gi|190360568 solute carrier family 39 (zinc transporter), member 14
           isoform a [Homo sapiens]
          Length = 492

 Score =  136 bits (342), Expect = 6e-32
 Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%)

Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
           C +   L      S  + +   +    CP +L Q+DSR C          +       SA
Sbjct: 91  CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150

Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
                   L V ++SL S L   ++  +     + LL +  ALA+GTL  +AL  L+P A
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210

Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
                 G   L +  +     V GG +L F  E +L +L       H G           
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265

Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
              +      K +N +  ++ P++ S           E    G            A    
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325

Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
           +G  +   G   + WM+ L DGLHN  DGLAIGA+F+     G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383

Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
           DF +LL +G+S ++ L  + +S      G  L  G+  G      W+F +  G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441

Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
            DM P +    +       +  P + +Q LGLL G  +M+ +T+
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484


>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
          Length = 469

 Score =  130 bits (326), Expect = 4e-30
 Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)

Query: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257
           AP    DL +  L + AL   +L   +P  +L L  +    PR  R LL  L + A G L
Sbjct: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180

Query: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304
            GDA LHL+PHA E               H+G G +    L  GL VL G+    V+E  
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236

Query: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360
           +   RH +G           +  TR          + +  Q++ E   +    Q+ +   
Sbjct: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293

Query: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417
             P   P   Q ++   + G D+    ++ L  D  HN TDGLAIGA+F  G   G+ TT
Sbjct: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352

Query: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470
           + V  HE+PHE+GDFA+L+QSG S +   RL LL+ V    G   A+L     VG  +  
Sbjct: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412

Query: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530
                WV   TAG F+YVA V +LP LLR   PL +   LL+ LGLL G  +M+ I  LE
Sbjct: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469


>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
          Length = 469

 Score =  130 bits (326), Expect = 4e-30
 Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)

Query: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257
           AP    DL +  L + AL   +L   +P  +L L  +    PR  R LL  L + A G L
Sbjct: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180

Query: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304
            GDA LHL+PHA E               H+G G +    L  GL VL G+    V+E  
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236

Query: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360
           +   RH +G           +  TR          + +  Q++ E   +    Q+ +   
Sbjct: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293

Query: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417
             P   P   Q ++   + G D+    ++ L  D  HN TDGLAIGA+F  G   G+ TT
Sbjct: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352

Query: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470
           + V  HE+PHE+GDFA+L+QSG S +   RL LL+ V    G   A+L     VG  +  
Sbjct: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412

Query: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530
                WV   TAG F+YVA V +LP LLR   PL +   LL+ LGLL G  +M+ I  LE
Sbjct: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469


>gi|205830426 solute carrier family 39 (zinc transporter), member 14
           isoform c [Homo sapiens]
          Length = 481

 Score =  129 bits (323), Expect = 9e-30
 Identities = 101/364 (27%), Positives = 154/364 (42%), Gaps = 36/364 (9%)

Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
           C +   L      S  + +   +    CP +L Q+DSR C          +       SA
Sbjct: 91  CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150

Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
                   L V ++SL S L   ++  +     + LL +  ALA+GTL  +AL  L+P A
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210

Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
                 G   L +  +     V GG +L F  E +L +L       H G           
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265

Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
              +      K +N +  ++ P++ S           E    G            A    
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325

Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
           +G  +   G   + WM+ L DGLHN  DGLAIGA+F+     G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383

Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
           DF +LL +G+S ++ L  + +S      G  L  G+  G      W+F +  G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441

Query: 491 VDML 494
            DM+
Sbjct: 442 ADMM 445


>gi|190014617 solute carrier family 39 (zinc transporter), member 13
           isoform a [Homo sapiens]
          Length = 371

 Score =  105 bits (262), Expect = 1e-22
 Identities = 103/332 (31%), Positives = 147/332 (44%), Gaps = 52/332 (15%)

Query: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267
           LL +L+     V  LL +P  +  +L    G   L+ LL F    A+G L G+  LHLLP
Sbjct: 72  LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127

Query: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323
            A      A PGG  +   +    GL V+ G+     LE M    +  G           
Sbjct: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178

Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383
             +  N DP   +  AL       +P A+          P L          G+      
Sbjct: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219

Query: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440
             + LL + + N T GLA+ A+F      GL TT+A+  HE+PHE+GDFA+LL++G    
Sbjct: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277

Query: 441 SFRRLLLLSLVSGALGLGGAVLG------VGLSLGPVPLTPWVFGVTAGVFLYVALVDML 494
           S  +L L + + G LG G A+        VG S        WV   T+G FLY+ALV++L
Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVL 337

Query: 495 PALLRPPEPLPTPHVLLQGLGLLLGGGLMLAI 526
           P LL   +P  +    LQ L LL  G +++ +
Sbjct: 338 PDLLEEEDPWRS----LQQLLLLCAGIVVMVL 365


>gi|40255101 solute carrier family 39 (zinc transporter), member 13
           isoform b [Homo sapiens]
          Length = 364

 Score =  103 bits (257), Expect = 4e-22
 Identities = 101/326 (30%), Positives = 145/326 (44%), Gaps = 47/326 (14%)

Query: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267
           LL +L+     V  LL +P  +  +L    G   L+ LL F    A+G L G+  LHLLP
Sbjct: 72  LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127

Query: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323
            A      A PGG  +   +    GL V+ G+     LE M    +  G           
Sbjct: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178

Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383
             +  N DP   +  AL       +P A+          P L          G+      
Sbjct: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219

Query: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440
             + LL + + N T GLA+ A+F      GL TT+A+  HE+PHE+GDFA+LL++G    
Sbjct: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277

Query: 441 SFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRP 500
           S  +L L + + G LG G A+       G      WV   T+G FLY+ALV++LP LL  
Sbjct: 278 SAAKLQLSTALGGLLGAGFAIC-TQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEE 336

Query: 501 PEPLPTPHVLLQGLGLLLGGGLMLAI 526
            +P  +    LQ L LL  G +++ +
Sbjct: 337 EDPWRS----LQQLLLLCAGIVVMVL 358


>gi|156415986 solute carrier family 39 (zinc transporter), member 2
           [Homo sapiens]
          Length = 309

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 50/140 (35%), Positives = 68/140 (48%), Gaps = 13/140 (9%)

Query: 373 HSHGH----QGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHE 428
           HSHGH      G     ++LL    H++ +GLA+G       ++ +   LAV  H+    
Sbjct: 150 HSHGHLPSPSKGPLRALVLLLSLSFHSVFEGLAVG--LQPTVAATVQLCLAVLAHKGLVV 207

Query: 429 LGDFAMLLQSGLSFR----RLLLLSLVSG-ALGLGGAVLGVGLSLGPVPLTPWVF-GVTA 482
            G    L+  G S R     +LLL+L+S   L +G AV G G S G   L   V  GV A
Sbjct: 208 FGVGMRLVHLGTSSRWAVFSILLLALMSPLGLAVGLAVTG-GDSEGGRGLAQAVLEGVAA 266

Query: 483 GVFLYVALVDMLPALLRPPE 502
           G FLYV  +++LP  L  PE
Sbjct: 267 GTFLYVTFLEILPRELASPE 286


>gi|40254928 solute carrier family 39 (zinc transporter), member 9
           [Homo sapiens]
          Length = 307

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 14/118 (11%)

Query: 389 LGDGLHNLTDGLAIGAAFSDGFSS-GLSTTLAVFCHELPHELGDFAMLLQSGLSFRR--- 444
           LG  +H   DG+A+GAA S   +S  L   +A+  H+ P   G  + L+ +GL   R   
Sbjct: 150 LGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRK 209

Query: 445 -LLLLSLVSGALGLGGAVLGVGLS------LGPVPLTPWVFGVTAGVFLYVALVDMLP 495
            LL+ +L +  + +   V  +GLS      L  V  T      +AG FLYVA V +LP
Sbjct: 210 HLLVFALAAPVMSM---VTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLP 264


>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
           sapiens]
          Length = 342

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%)

Query: 386 MVLLGDGLHNLTDGLAIGAAF-------SDGFSSGLSTTLAVFCHELPHELGDFAMLLQS 438
           +++L   +HN+ +GLA+G  F       S  F S  +  + +     P  L     L  +
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255

Query: 439 GLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
           G S  R      +SG +     V G    +   P+ P+     AG  +YV + D++P
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 312


>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
           sapiens]
          Length = 335

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%)

Query: 386 MVLLGDGLHNLTDGLAIGAAF-------SDGFSSGLSTTLAVFCHELPHELGDFAMLLQS 438
           +++L   +HN+ +GLA+G  F       S  F S  +  + +     P  L     L  +
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248

Query: 439 GLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
           G S  R      +SG +     V G    +   P+ P+     AG  +YV + D++P
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 305


>gi|58761544 amine oxidase (flavin containing) domain 2 isoform a
           [Homo sapiens]
          Length = 876

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 15/113 (13%)

Query: 316 RCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH 375
           R  RRKR  +E R +D E+ + ++     +  E  A+ ++EK    PP  APP  +  S 
Sbjct: 109 RTSRRKRAKVEYREMD-ESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESE 167

Query: 376 GHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHE 428
             +             GL + + G      + DG +SG+    A F   LPH+
Sbjct: 168 PEEPSGQ-------AGGLQDDSSG-----GYGDGQASGVEG--AAFQSRLPHD 206



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 333 ENGSGMALQPL----QAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQG 379
           ENGS +A QP      A   PGA G+R    + PP  +PPG      G  G
Sbjct: 32  ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAG 82


>gi|58761546 amine oxidase (flavin containing) domain 2 isoform b
           [Homo sapiens]
          Length = 852

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 333 ENGSGMALQPL----QAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQG 379
           ENGS +A QP      A   PGA G+R    + PP  +PPG      G  G
Sbjct: 32  ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAG 82



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)

Query: 316 RCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHS 374
           R  RRKR  +E R +D E+ + ++     +  E  A+ ++EK    PP  APP  +  S
Sbjct: 109 RTSRRKRAKVEYREMD-ESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENES 166


>gi|21361423 solute carrier family 39 (zinc transporter), member 1
           [Homo sapiens]
          Length = 324

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 7/132 (5%)

Query: 393 LHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVS 452
           LH++ +GLA+G       +  +   LA+  H+    +     LLQS L  + +    ++ 
Sbjct: 189 LHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILF 246

Query: 453 GALGLGGAVLGVGLSLGPVPLTPW----VFGVTAGVFLYVALVDMLPALLRPPEP-LPTP 507
             +   G  LG  L+    PL       + G+ AG FLY+  +++LP  L   E  +   
Sbjct: 247 SCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKV 306

Query: 508 HVLLQGLGLLLG 519
            +LL G  LL G
Sbjct: 307 ILLLAGFALLTG 318


>gi|123173757 RAVER1 [Homo sapiens]
          Length = 756

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 63/192 (32%), Positives = 66/192 (34%), Gaps = 49/192 (25%)

Query: 202 APAPPGDLLSALLQSALAVLLLS----LPSPLSLLLLRLLGPR-----LLRPLL------ 246
           AP PPG  + A L +A A  L      LP P  L LL  LGP      LL PLL      
Sbjct: 315 APGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGG 374

Query: 247 --GFLGA-----LAVGTLCGDALLHLLPHAQEGRHAG-PGGLPEKDLGPGLSVLGGLFLL 298
             G LGA     L  G     ALL L    Q  +  G  G  P   L PG      L   
Sbjct: 375 KQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPL--- 431

Query: 299 FVLENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKN 358
                 LG L   G  P              L P  G    L P    P   A G RE  
Sbjct: 432 ------LGELPAGGGLP------------PELPPRRGKPPPLLPSVLGP---AGGDREAL 470

Query: 359 SQHPPA--LAPP 368
              PPA  L PP
Sbjct: 471 GLGPPAAQLTPP 482


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.143    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,546,861
Number of Sequences: 37866
Number of extensions: 1464179
Number of successful extensions: 5275
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 5085
Number of HSP's gapped (non-prelim): 192
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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