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Search of human proteins with 206597539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
(540 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597541 solute carrier family 39 (metal ion transporter), m... 1093 0.0
gi|206597539 solute carrier family 39 (metal ion transporter), m... 1093 0.0
gi|187936949 solute carrier family 39 (zinc transporter), member... 235 9e-62
gi|55741750 solute carrier family 39 (zinc transporter), member ... 235 9e-62
gi|115430259 solute carrier family 39 (zinc transporter), member... 201 1e-51
gi|115430255 solute carrier family 39 (zinc transporter), member... 201 1e-51
gi|223633939 solute carrier family 39 (zinc transporter), member... 168 1e-41
gi|223633937 solute carrier family 39 (zinc transporter), member... 162 6e-40
gi|153252201 solute carrier family 39 (zinc transporter), member... 156 5e-38
gi|205830407 solute carrier family 39 (zinc transporter), member... 142 8e-34
gi|24586665 solute carrier family 39 (zinc transporter), member ... 141 1e-33
gi|205830403 solute carrier family 39 (zinc transporter), member... 141 1e-33
gi|153252214 solute carrier family 39 (zinc transporter), member... 139 9e-33
gi|205830405 solute carrier family 39 (zinc transporter), member... 139 9e-33
gi|190358541 solute carrier family 39 (zinc transporter), member... 137 2e-32
gi|205830424 solute carrier family 39 (zinc transporter), member... 136 6e-32
gi|190360568 solute carrier family 39 (zinc transporter), member... 136 6e-32
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 130 4e-30
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 130 4e-30
gi|205830426 solute carrier family 39 (zinc transporter), member... 129 9e-30
gi|190014617 solute carrier family 39 (zinc transporter), member... 105 1e-22
gi|40255101 solute carrier family 39 (zinc transporter), member ... 103 4e-22
gi|156415986 solute carrier family 39 (zinc transporter), member... 50 5e-06
gi|40254928 solute carrier family 39 (zinc transporter), member ... 45 1e-04
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 44 5e-04
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 44 5e-04
gi|58761544 amine oxidase (flavin containing) domain 2 isoform a... 38 0.021
gi|58761546 amine oxidase (flavin containing) domain 2 isoform b... 35 0.13
gi|21361423 solute carrier family 39 (zinc transporter), member ... 35 0.13
gi|123173757 RAVER1 [Homo sapiens] 35 0.13
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 1093 bits (2827), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60
MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR
Sbjct: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60
Query: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120
LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL
Sbjct: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120
Query: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180
EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ
Sbjct: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180
Query: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240
FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR
Sbjct: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240
Query: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300
LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV
Sbjct: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300
Query: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360
LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ
Sbjct: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360
Query: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV
Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
Query: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540
TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG
Sbjct: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 1093 bits (2827), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60
MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR
Sbjct: 1 MMGSPVSHLLAGFCVWVVLGWVGGSVPNLGPAEQEQNHYLAQLFGLYGENGTLTAGGLAR 60
Query: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120
LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL
Sbjct: 61 LLHSLGLGRVQGLRLGQHGPLTGRAASPAADNSTHRPQNPELSVDVWAGMPLGPSGWGDL 120
Query: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180
EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ
Sbjct: 121 EESKAPHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNFGLSPAAPLTPRQ 180
Query: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240
FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR
Sbjct: 181 FALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSALAVLLLSLPSPLSLLLLRLLGPR 240
Query: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300
LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV
Sbjct: 241 LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFV 300
Query: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360
LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ
Sbjct: 301 LENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQ 360
Query: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV
Sbjct: 361 HPPALAPPGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV
Sbjct: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
Query: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540
TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG
Sbjct: 481 TAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERLLPVTTEG 540
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 235 bits (599), Expect = 9e-62
Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%)
Query: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168
L P G+L ++ APH+ S L D + DH +E CLN +QLL +
Sbjct: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347
Query: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213
G +P++ F LCPALLYQIDSR+CI D+ SA
Sbjct: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407
Query: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272
+ +++ ++SL S L ++L+ ++ + LL FL ALAVGT+ GDALLHLLPH+Q G
Sbjct: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467
Query: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313
+HA G L E D + GL LGG++LLF++E+ + + +H RG
Sbjct: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527
Query: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353
+ ++ R L L + + + L+PL + +G
Sbjct: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587
Query: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375
Q+E KN +H A H G H H
Sbjct: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647
Query: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421
H G +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF
Sbjct: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707
Query: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481
CHELPHELGDFA+LL++G++ ++ ++ +L+S + G ++G + +T W+F VT
Sbjct: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767
Query: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
AG+FLYVALVDMLP +L P +LQ LGLL G +ML I L E++++
Sbjct: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826
Score = 42.7 bits (99), Expect = 8e-04
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68
AE E+ +Y+ +LF YGENG L+ GL +LL +LGLG
Sbjct: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 235 bits (599), Expect = 9e-62
Identities = 180/539 (33%), Positives = 262/539 (48%), Gaps = 125/539 (23%)
Query: 112 LGPSGWGDLEESK---APHLPRGPAPSGLDLLHRLLLLDHSLADHLNEDCLNGSQLLVNF 168
L P G+L ++ APH+ S L D + DH +E CLN +QLL +
Sbjct: 297 LDPDNEGELRHTRKREAPHVKNNAIIS--------LRKDLNEDDHHHE-CLNVTQLLKYY 347
Query: 169 GLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDL---------------LSAL 213
G +P++ F LCPALLYQIDSR+CI D+ SA
Sbjct: 348 GHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAW 407
Query: 214 LQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG- 272
+ +++ ++SL S L ++L+ ++ + LL FL ALAVGT+ GDALLHLLPH+Q G
Sbjct: 408 ICGIISITVISLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGH 467
Query: 273 ----RHAGPGG----------LPEKD-LGPGLSVLGGLFLLFVLENMLGLLRH----RGL 313
+HA G L E D + GL LGG++LLF++E+ + + +H RG
Sbjct: 468 DHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGK 527
Query: 314 RPRCCRRKR------RNLETRNL-DPENGSGMALQPLQAAPE-------------PGAQG 353
+ ++ R L L + + + L+PL + +G
Sbjct: 528 QKWFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEG 587
Query: 354 QRE---KN---------------------SQHPPALAPPGHQG--------------HSH 375
Q+E KN +H A H G H H
Sbjct: 588 QQESPPKNYLCIEEEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKH 647
Query: 376 GHQ--------------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVF 421
H G +I WMV++GDG+HN +DGLAIGAAFS G + G+ST++AVF
Sbjct: 648 SHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVF 707
Query: 422 CHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVT 481
CHELPHELGDFA+LL++G++ ++ ++ +L+S + G ++G + +T W+F VT
Sbjct: 708 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVT 767
Query: 482 AGVFLYVALVDMLPALLRPPEP------LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
AG+FLYVALVDMLP +L P +LQ LGLL G +ML I L E++++
Sbjct: 768 AGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIV 826
Score = 42.7 bits (99), Expect = 8e-04
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 32 AEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLG 68
AE E+ +Y+ +LF YGENG L+ GL +LL +LGLG
Sbjct: 56 AENEKKYYIEKLFERYGENGRLSFFGLEKLLTNLGLG 92
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 201 bits (512), Expect = 1e-51
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)
Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L
Sbjct: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 303
Query: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
+LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P
Sbjct: 304 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 363
Query: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
GL + L++L GL+ F+ EN+ LL R L C + +
Sbjct: 364 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 422
Query: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
+G + L P + P+P +G R + ++ P L P + S + + +M+
Sbjct: 423 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 476
Query: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 477 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 536
Query: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
+L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P
Sbjct: 537 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 593
Query: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
LL +GLL G ++L ++L E+
Sbjct: 594 LLFLLHNVGLLGGWTVLLLLSLYED 618
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 201 bits (512), Expect = 1e-51
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)
Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L
Sbjct: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 328
Query: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
+LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P
Sbjct: 329 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 388
Query: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
GL + L++L GL+ F+ EN+ LL R L C + +
Sbjct: 389 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 447
Query: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
+G + L P + P+P +G R + ++ P L P + S + + +M+
Sbjct: 448 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 501
Query: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 502 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 561
Query: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
+L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P
Sbjct: 562 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 618
Query: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
LL +GLL G ++L ++L E+
Sbjct: 619 LLFLLHNVGLLGGWTVLLLLSLYED 643
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 168 bits (425), Expect = 1e-41
Identities = 128/398 (32%), Positives = 191/398 (47%), Gaps = 34/398 (8%)
Query: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
++ C + QL+ F + ++ F + P ++ Q+ S C A PP L
Sbjct: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365
Query: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P
Sbjct: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425
Query: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
H QE G + + + ++GG+ F++E LL + P
Sbjct: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPN--------- 472
Query: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH--GHQGGTD- 382
+ + L NG L E Q R K++ +P Q G ++
Sbjct: 473 DKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNR 532
Query: 383 -------ITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAML 435
+ M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+L
Sbjct: 533 KCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVL 592
Query: 436 LQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
L SGLS + +L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP
Sbjct: 593 LSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLP 651
Query: 496 ALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLEERL 533
+ P LLQ GL+LG +L + + E+ +
Sbjct: 652 EMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 162 bits (411), Expect = 6e-40
Identities = 125/388 (32%), Positives = 188/388 (48%), Gaps = 51/388 (13%)
Query: 155 NEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI---GAPAPAPPGDLLS 211
++ C + QL+ F + ++ F + P ++ Q+ S C A PP L
Sbjct: 307 DQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPP-TTLE 365
Query: 212 ALLQSALAVLLLSLPSPLSLLLLRLLG-PRLLRPLLGFLGALAVGTLCGDALLHLLP--- 267
S +AV LL+L S L L+ R +L LAVGTL GDALLHL+P
Sbjct: 366 KYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVL 425
Query: 268 --HAQEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRNL 325
H QE G + + + ++GG+ F++E LL + P +
Sbjct: 426 GLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILL----VSPNDKK------ 475
Query: 326 ETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDITW 385
PE+ QAA P G +++ A++ +
Sbjct: 476 -----SPEDS--------QAAEMP--IGSMTASNRKCKAISL---------------LAI 505
Query: 386 MVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRL 445
M+L+GD LHN DGLAIGAAFS SG++TT+A+ CHE+PHE+GDFA+LL SGLS +
Sbjct: 506 MILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTA 565
Query: 446 LLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLP 505
+L++ +S G +G+ +S P + W+F VTAG+FLY++LV+MLP + P
Sbjct: 566 ILMNFISSLTAFMGLYIGLSVSADPC-VQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRP 624
Query: 506 TPHVLLQGLGLLLGGGLMLAITLLEERL 533
LLQ GL+LG +L + + E+ +
Sbjct: 625 WMMFLLQNFGLILGWLSLLLLAIYEQNI 652
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 156 bits (394), Expect = 5e-38
Identities = 79/178 (44%), Positives = 116/178 (65%), Gaps = 13/178 (7%)
Query: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
H HSH + G + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV
Sbjct: 573 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 632
Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
FCHELPHELGDFA+LL++G++ ++ +L + +S L G G+ + ++ W+F +
Sbjct: 633 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 692
Query: 481 TAGVFLYVALVDMLPALLRPPEP----LPTPHVLLQGLGLLLGGGLMLAITLLEERLL 534
TAG+F+YVALVDM+P +L + LQ G+LLG G+ML I++ E +++
Sbjct: 693 TAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIV 750
Score = 95.5 bits (236), Expect = 1e-19
Identities = 70/240 (29%), Positives = 113/240 (47%), Gaps = 33/240 (13%)
Query: 156 EDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDL 209
++C N S+LL + G+ PL +F LCPA++ QID+R C+ A P L
Sbjct: 262 QECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSL 321
Query: 210 LSALLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
A + +A+ ++S S L ++L+ L+ + LL FL ALAVGTL GDA LHLLPH+
Sbjct: 322 QIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHS 381
Query: 270 QEGRHAGPGG---LPEKDLGP---------------------GLSVLGGLFLLFVLENML 305
H E GP GL+ LGGL+ +F++E++L
Sbjct: 382 HASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVL 441
Query: 306 GLLRHRGLRPRCCRRKRRN---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362
L++ + + ++K N +E + + S ++ + + +G +SQ P
Sbjct: 442 TLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 501
Score = 36.2 bits (82), Expect = 0.078
Identities = 15/48 (31%), Positives = 30/48 (62%)
Query: 28 NLGPAEQEQNHYLAQLFGLYGENGTLTAGGLARLLHSLGLGRVQGLRL 75
N+ A + ++L QLF YGEN +L+ G +LL ++G+ +++ + +
Sbjct: 45 NVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHI 92
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 142 bits (358), Expect = 8e-34
Identities = 119/407 (29%), Positives = 179/407 (43%), Gaps = 54/407 (13%)
Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
H + CL ++ G S A +T +F+++CPA+L Q++ C P
Sbjct: 2 HQHAQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 61
Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A
Sbjct: 62 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 119
Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
G P+ D + ++V GG +LLF E ML +L H + +
Sbjct: 120 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 174
Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
+ + L NG P A E G++E +S P L+
Sbjct: 175 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 232
Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH
Sbjct: 233 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 280
Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY
Sbjct: 281 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 338
Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
++L DM P +LR ++Q G+L G +L ITL
Sbjct: 339 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 385
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 141 bits (356), Expect = 1e-33
Identities = 120/407 (29%), Positives = 180/407 (44%), Gaps = 55/407 (13%)
Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
H N+ CL ++ G S A +T +F+++CPA+L Q++ C P
Sbjct: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128
Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A
Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186
Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
G P+ D + ++V GG +LLF E ML +L H + +
Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241
Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
+ + L NG P A E G++E +S P L+
Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299
Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH
Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347
Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY
Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405
Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
++L DM P +LR ++Q G+L G +L ITL
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 452
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 141 bits (356), Expect = 1e-33
Identities = 120/407 (29%), Positives = 180/407 (44%), Gaps = 55/407 (13%)
Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
H N+ CL ++ G S A +T +F+++CPA+L Q++ C P
Sbjct: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128
Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A
Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186
Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
G P+ D + ++V GG +LLF E ML +L H + +
Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241
Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
+ + L NG P A E G++E +S P L+
Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299
Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH
Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347
Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY
Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405
Query: 488 VALVDMLPA---LLRPP---EPLPTPHVLLQGLGLLLGGGLMLAITL 528
++L DM P +LR ++Q G+L G +L ITL
Sbjct: 406 ISLADMFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITL 452
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 139 bits (349), Expect = 9e-33
Identities = 66/134 (49%), Positives = 94/134 (70%), Gaps = 9/134 (6%)
Query: 370 HQGHSHGHQ---------GGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAV 420
H HSH + G + WMV++GDGLHN +DGLAIGAAF++G SSGLST++AV
Sbjct: 298 HHPHSHSQRYSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAV 357
Query: 421 FCHELPHELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGV 480
FCHELPHELGDFA+LL++G++ ++ +L + +S L G G+ + ++ W+F +
Sbjct: 358 FCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFAL 417
Query: 481 TAGVFLYVALVDML 494
TAG+F+YVALVDM+
Sbjct: 418 TAGLFMYVALVDMV 431
Score = 81.6 bits (200), Expect = 2e-15
Identities = 64/221 (28%), Positives = 102/221 (46%), Gaps = 33/221 (14%)
Query: 175 PLTPRQFALLCPALLYQIDSRVCI------GAPAPAPPGDLLSALLQSALAVLLLSLPSP 228
PL +F LCPA++ QID+R C+ A P L A + +A+ ++S S
Sbjct: 6 PLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSL 65
Query: 229 LSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEGRHAGPGG---LPEKDL 285
L ++L+ L+ + LL FL ALAVGTL GDA LHLLPH+ H E
Sbjct: 66 LGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKR 125
Query: 286 GP---------------------GLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRRN 324
GP GL+ LGGL+ +F++E++L L++ + + ++K N
Sbjct: 126 GPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPEN 185
Query: 325 ---LETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHP 362
+E + + S ++ + + +G +SQ P
Sbjct: 186 DDDVEIKKQLSKYESQLSTNEEKVDTDDRTEGYLRADSQEP 226
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 139 bits (349), Expect = 9e-33
Identities = 110/370 (29%), Positives = 166/370 (44%), Gaps = 49/370 (13%)
Query: 153 HLNEDCLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA 212
H N+ CL ++ G S A +T +F+++CPA+L Q++ C P
Sbjct: 70 HFNQ-CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEV 128
Query: 213 LLQSALAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHAQEG 272
L+V +++L S L L+L L+ +L F LA+GTL +A+ L+P A
Sbjct: 129 WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAF-- 186
Query: 273 RHAGPGGLPEKD--LGPGLSVLGGLFLLFVLENMLGLLR-------HRGLRPRCCRRKRR 323
G P+ D + ++V GG +LLF E ML +L H + +
Sbjct: 187 -----GFDPKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEK 241
Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQ-------------GQREKNS---QHPPALAP 367
+ + L NG P A E G++E +S P L+
Sbjct: 242 THQPKALPAINGVTCYANP--AVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSE 299
Query: 368 PGHQGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPH 427
G I WM+ L D LHN DGLAIGA+ + GLST++A+ C E PH
Sbjct: 300 IG------------TIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPH 347
Query: 428 ELGDFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLY 487
ELGDF +LL +G+S R+ LL + +S G G+ + P +F + G+FLY
Sbjct: 348 ELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNI--IFALAGGMFLY 405
Query: 488 VALVDMLPAL 497
++L DM P +
Sbjct: 406 ISLADMFPEM 415
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 137 bits (346), Expect = 2e-32
Identities = 111/404 (27%), Positives = 173/404 (42%), Gaps = 43/404 (10%)
Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
C + L S + + + CP +L Q+DSR C + SA
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
L+V L++L S L +L+L +L + AL++GTL +AL L+P A
Sbjct: 151 VEVWGFGFLSVSLINLASLLGVLVLPCTEKAFFSRVLTYFIALSIGTLLSNALFQLIPEA 210
Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
G L + + V GG +L F E +L +L H G
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265
Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
+ K +N + ++ P++ S E G A
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325
Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
+G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383
Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441
Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
DM P + + + P + +Q LGLL G +M+ +T+
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 136 bits (342), Expect = 6e-32
Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%)
Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
C + L S + + + CP +L Q+DSR C + SA
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
G L + + V GG +L F E +L +L H G
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265
Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
+ K +N + ++ P++ S E G A
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325
Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
+G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383
Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441
Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
DM P + + + P + +Q LGLL G +M+ +T+
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 136 bits (342), Expect = 6e-32
Identities = 111/404 (27%), Positives = 172/404 (42%), Gaps = 43/404 (10%)
Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
C + L S + + + CP +L Q+DSR C + SA
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
G L + + V GG +L F E +L +L H G
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265
Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
+ K +N + ++ P++ S E G A
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325
Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
+G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383
Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441
Query: 491 VDMLPALLRPPE------PLPTPHVLLQGLGLLLGGGLMLAITL 528
DM P + + + P + +Q LGLL G +M+ +T+
Sbjct: 442 ADMFPEMNEVCQEDERKGSILIPFI-IQNLGLLTGFTIMVVLTM 484
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 130 bits (326), Expect = 4e-30
Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)
Query: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257
AP DL + L + AL +L +P +L L + PR R LL L + A G L
Sbjct: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180
Query: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304
GDA LHL+PHA E H+G G + L GL VL G+ V+E
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236
Query: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360
+ RH +G + TR + + Q++ E + Q+ +
Sbjct: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293
Query: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417
P P Q ++ + G D+ ++ L D HN TDGLAIGA+F G G+ TT
Sbjct: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352
Query: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470
+ V HE+PHE+GDFA+L+QSG S + RL LL+ V G A+L VG +
Sbjct: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412
Query: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530
WV TAG F+YVA V +LP LLR PL + LL+ LGLL G +M+ I LE
Sbjct: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 130 bits (326), Expect = 4e-30
Identities = 124/360 (34%), Positives = 169/360 (46%), Gaps = 43/360 (11%)
Query: 202 APAPPGDLLSALLQS-ALAVLLLSLPSPLSLLLLRLL---GPRLLRPLLGFLGALAVGTL 257
AP DL + L + AL +L +P +L L + PR R LL L + A G L
Sbjct: 122 APGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRH-RSLLQILLSFASGGL 180
Query: 258 CGDALLHLLPHAQEGR-------------HAGPGGLPEKDLGPGLSVLGGLFLLFVLENM 304
GDA LHL+PHA E H+G G + L GL VL G+ V+E
Sbjct: 181 LGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPI----LSVGLWVLSGIVAFLVVEKF 236
Query: 305 LGLLRH-RGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQG---QREKNSQ 360
+ RH +G + TR + + Q++ E + Q+ +
Sbjct: 237 V---RHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGS 293
Query: 361 HPPALAPPGHQGHSHGHQGGTDIT---WMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTT 417
P P Q ++ + G D+ ++ L D HN TDGLAIGA+F G G+ TT
Sbjct: 294 TVPKDGPVRPQ-NAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTT 352
Query: 418 LAVFCHELPHELGDFAMLLQSGLSFR---RLLLLSLVSGALGLGGAVL----GVGLSLGP 470
+ V HE+PHE+GDFA+L+QSG S + RL LL+ V G A+L VG +
Sbjct: 353 MTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAG 412
Query: 471 VPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPTPHVLLQGLGLLLGGGLMLAITLLE 530
WV TAG F+YVA V +LP LLR PL + LL+ LGLL G +M+ I LE
Sbjct: 413 GAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQS---LLEVLGLLGGVIMMVLIAHLE 469
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 129 bits (323), Expect = 9e-30
Identities = 101/364 (27%), Positives = 154/364 (42%), Gaps = 36/364 (9%)
Query: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSALLQSA 217
C + L S + + + CP +L Q+DSR C + SA
Sbjct: 91 CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA 150
Query: 218 --------LAVLLLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLPHA 269
L V ++SL S L ++ + + LL + ALA+GTL +AL L+P A
Sbjct: 151 VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEA 210
Query: 270 QEGRHAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLL------RHRGL---------- 313
G L + + V GG +L F E +L +L H G
Sbjct: 211 -----FGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPS 265
Query: 314 ---RPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGH 370
+ K +N + ++ P++ S E G A
Sbjct: 266 KKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWL 325
Query: 371 QGHSHGHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELG 430
+G + G + WM+ L DGLHN DGLAIGA+F+ G+ST++A+ C E PHELG
Sbjct: 326 KGVRYSDIG--TLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELG 383
Query: 431 DFAMLLQSGLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVAL 490
DF +LL +G+S ++ L + +S G L G+ G W+F + G+FLY++L
Sbjct: 384 DFVILLNAGMSIQQALFFNFLSACCCYLG--LAFGILAGSHFSANWIFALAGGMFLYISL 441
Query: 491 VDML 494
DM+
Sbjct: 442 ADMM 445
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 105 bits (262), Expect = 1e-22
Identities = 103/332 (31%), Positives = 147/332 (44%), Gaps = 52/332 (15%)
Query: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267
LL +L+ V LL +P + +L G L+ LL F A+G L G+ LHLLP
Sbjct: 72 LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127
Query: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323
A A PGG + + GL V+ G+ LE M + G
Sbjct: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178
Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383
+ N DP + AL +P A+ P L G+
Sbjct: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219
Query: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440
+ LL + + N T GLA+ A+F GL TT+A+ HE+PHE+GDFA+LL++G
Sbjct: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
Query: 441 SFRRLLLLSLVSGALGLGGAVLG------VGLSLGPVPLTPWVFGVTAGVFLYVALVDML 494
S +L L + + G LG G A+ VG S WV T+G FLY+ALV++L
Sbjct: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVL 337
Query: 495 PALLRPPEPLPTPHVLLQGLGLLLGGGLMLAI 526
P LL +P + LQ L LL G +++ +
Sbjct: 338 PDLLEEEDPWRS----LQQLLLLCAGIVVMVL 365
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 103 bits (257), Expect = 4e-22
Identities = 101/326 (30%), Positives = 145/326 (44%), Gaps = 47/326 (14%)
Query: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267
LL +L+ V LL +P + +L G L+ LL F A+G L G+ LHLLP
Sbjct: 72 LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127
Query: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323
A A PGG + + GL V+ G+ LE M + G
Sbjct: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178
Query: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383
+ N DP + AL +P A+ P L G+
Sbjct: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219
Query: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440
+ LL + + N T GLA+ A+F GL TT+A+ HE+PHE+GDFA+LL++G
Sbjct: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
Query: 441 SFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRP 500
S +L L + + G LG G A+ G WV T+G FLY+ALV++LP LL
Sbjct: 278 SAAKLQLSTALGGLLGAGFAIC-TQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEE 336
Query: 501 PEPLPTPHVLLQGLGLLLGGGLMLAI 526
+P + LQ L LL G +++ +
Sbjct: 337 EDPWRS----LQQLLLLCAGIVVMVL 358
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 50.1 bits (118), Expect = 5e-06
Identities = 50/140 (35%), Positives = 68/140 (48%), Gaps = 13/140 (9%)
Query: 373 HSHGH----QGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHE 428
HSHGH G ++LL H++ +GLA+G ++ + LAV H+
Sbjct: 150 HSHGHLPSPSKGPLRALVLLLSLSFHSVFEGLAVG--LQPTVAATVQLCLAVLAHKGLVV 207
Query: 429 LGDFAMLLQSGLSFR----RLLLLSLVSG-ALGLGGAVLGVGLSLGPVPLTPWVF-GVTA 482
G L+ G S R +LLL+L+S L +G AV G G S G L V GV A
Sbjct: 208 FGVGMRLVHLGTSSRWAVFSILLLALMSPLGLAVGLAVTG-GDSEGGRGLAQAVLEGVAA 266
Query: 483 GVFLYVALVDMLPALLRPPE 502
G FLYV +++LP L PE
Sbjct: 267 GTFLYVTFLEILPRELASPE 286
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 14/118 (11%)
Query: 389 LGDGLHNLTDGLAIGAAFSDGFSS-GLSTTLAVFCHELPHELGDFAMLLQSGLSFRR--- 444
LG +H DG+A+GAA S +S L +A+ H+ P G + L+ +GL R
Sbjct: 150 LGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRK 209
Query: 445 -LLLLSLVSGALGLGGAVLGVGLS------LGPVPLTPWVFGVTAGVFLYVALVDMLP 495
LL+ +L + + + V +GLS L V T +AG FLYVA V +LP
Sbjct: 210 HLLVFALAAPVMSM---VTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLP 264
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%)
Query: 386 MVLLGDGLHNLTDGLAIGAAF-------SDGFSSGLSTTLAVFCHELPHELGDFAMLLQS 438
+++L +HN+ +GLA+G F S F S + + + P L L +
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 439 GLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
G S R +SG + V G + P+ P+ AG +YV + D++P
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 312
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%)
Query: 386 MVLLGDGLHNLTDGLAIGAAF-------SDGFSSGLSTTLAVFCHELPHELGDFAMLLQS 438
+++L +HN+ +GLA+G F S F S + + + P L L +
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 439 GLSFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLP 495
G S R +SG + V G + P+ P+ AG +YV + D++P
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 305
>gi|58761544 amine oxidase (flavin containing) domain 2 isoform a
[Homo sapiens]
Length = 876
Score = 38.1 bits (87), Expect = 0.021
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 15/113 (13%)
Query: 316 RCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSH 375
R RRKR +E R +D E+ + ++ + E A+ ++EK PP APP + S
Sbjct: 109 RTSRRKRAKVEYREMD-ESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESE 167
Query: 376 GHQGGTDITWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHE 428
+ GL + + G + DG +SG+ A F LPH+
Sbjct: 168 PEEPSGQ-------AGGLQDDSSG-----GYGDGQASGVEG--AAFQSRLPHD 206
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
Query: 333 ENGSGMALQPL----QAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQG 379
ENGS +A QP A PGA G+R + PP +PPG G G
Sbjct: 32 ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAG 82
>gi|58761546 amine oxidase (flavin containing) domain 2 isoform b
[Homo sapiens]
Length = 852
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
Query: 333 ENGSGMALQPL----QAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQG 379
ENGS +A QP A PGA G+R + PP +PPG G G
Sbjct: 32 ENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAG 82
Score = 33.9 bits (76), Expect = 0.39
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 316 RCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHS 374
R RRKR +E R +D E+ + ++ + E A+ ++EK PP APP + S
Sbjct: 109 RTSRRKRAKVEYREMD-ESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENES 166
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 35.4 bits (80), Expect = 0.13
Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 7/132 (5%)
Query: 393 LHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLLSLVS 452
LH++ +GLA+G + + LA+ H+ + LLQS L + + ++
Sbjct: 189 LHSVFEGLAVG--LQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILF 246
Query: 453 GALGLGGAVLGVGLSLGPVPLTPW----VFGVTAGVFLYVALVDMLPALLRPPEP-LPTP 507
+ G LG L+ PL + G+ AG FLY+ +++LP L E +
Sbjct: 247 SCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKV 306
Query: 508 HVLLQGLGLLLG 519
+LL G LL G
Sbjct: 307 ILLLAGFALLTG 318
>gi|123173757 RAVER1 [Homo sapiens]
Length = 756
Score = 35.4 bits (80), Expect = 0.13
Identities = 63/192 (32%), Positives = 66/192 (34%), Gaps = 49/192 (25%)
Query: 202 APAPPGDLLSALLQSALAVLLLS----LPSPLSLLLLRLLGPR-----LLRPLL------ 246
AP PPG + A L +A A L LP P L LL LGP LL PLL
Sbjct: 315 APGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGG 374
Query: 247 --GFLGA-----LAVGTLCGDALLHLLPHAQEGRHAG-PGGLPEKDLGPGLSVLGGLFLL 298
G LGA L G ALL L Q + G G P L PG L
Sbjct: 375 KQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPL--- 431
Query: 299 FVLENMLGLLRHRGLRPRCCRRKRRNLETRNLDPENGSGMALQPLQAAPEPGAQGQREKN 358
LG L G P L P G L P P A G RE
Sbjct: 432 ------LGELPAGGGLP------------PELPPRRGKPPPLLPSVLGP---AGGDREAL 470
Query: 359 SQHPPA--LAPP 368
PPA L PP
Sbjct: 471 GLGPPAAQLTPP 482
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.143 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,546,861
Number of Sequences: 37866
Number of extensions: 1464179
Number of successful extensions: 5275
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 5085
Number of HSP's gapped (non-prelim): 192
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.