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Search of human proteins with 206597509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens] 1037 0.0
gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens] 1018 0.0
gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens] 1009 0.0
gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens] 846 0.0
gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens] 297 2e-80
gi|113204622 stromal membrane-associated GTPase-activating prote... 72 1e-12
gi|21264558 stromal membrane-associated GTPase-activating protei... 71 3e-12
gi|23943872 small ArfGAP2 [Homo sapiens] 70 6e-12
gi|33946327 nucleoporin 214kDa [Homo sapiens] 68 2e-11
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i... 66 7e-11
gi|6806913 centaurin, alpha 1 [Homo sapiens] 66 9e-11
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ... 65 2e-10
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 59 8e-09
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 59 8e-09
gi|24430146 nucleoporin 153kDa [Homo sapiens] 57 5e-08
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 56 9e-08
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 55 1e-07
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 55 1e-07
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 55 1e-07
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 55 2e-07
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 54 3e-07
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 54 3e-07
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 54 3e-07
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 54 5e-07
gi|161016767 mucin 21 [Homo sapiens] 54 5e-07
gi|214829714 ADP-ribosylation factor GTPase activating protein 3... 53 8e-07
gi|19111150 angiomotin isoform 2 [Homo sapiens] 53 8e-07
gi|166064029 angiomotin isoform 1 [Homo sapiens] 53 8e-07
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 53 8e-07
gi|187608516 centaurin, beta 2 [Homo sapiens] 52 2e-06
>gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]
Length = 522
Score = 1037 bits (2682), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNA 240
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNA
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNA 240
Query: 241 NFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAG 300
NFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAG
Sbjct: 241 NFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAG 300
Query: 301 QGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNA 360
QGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNA
Sbjct: 301 QGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNA 360
Query: 361 SSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA 420
SSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA
Sbjct: 361 SSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA 420
Query: 421 ATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFG 480
ATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFG
Sbjct: 421 ATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFG 480
Query: 481 QTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
QTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
Sbjct: 481 QTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
>gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]
Length = 562
Score = 1018 bits (2631), Expect = 0.0
Identities = 522/562 (92%), Positives = 522/562 (92%), Gaps = 40/562 (7%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA--------- 231
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
Query: 232 -------------------------------GGSAASVNANFAHFDNFPKSSSADFGTFN 260
GGSAASVNANFAHFDNFPKSSSADFGTFN
Sbjct: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN 300
Query: 261 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 320
TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
Sbjct: 301 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 360
Query: 321 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 380
VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
Sbjct: 361 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 420
Query: 381 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 440
SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
Sbjct: 421 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 480
Query: 441 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN 500
SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN
Sbjct: 481 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN 540
Query: 501 PFMTGAPTGQFPTGSSSTNPFL 522
PFMTGAPTGQFPTGSSSTNPFL
Sbjct: 541 PFMTGAPTGQFPTGSSSTNPFL 562
>gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]
Length = 560
Score = 1009 bits (2608), Expect = 0.0
Identities = 520/562 (92%), Positives = 520/562 (92%), Gaps = 42/562 (7%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA--------- 231
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF 240
Query: 232 -------------------------------GGSAASVNANFAHFDNFPKSSSADFGTFN 260
GGSAASVNANFAHFDNFPKSSSADFGTFN
Sbjct: 241 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN 300
Query: 261 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 320
TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
Sbjct: 301 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 360
Query: 321 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 380
VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
Sbjct: 361 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 420
Query: 381 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 440
SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
Sbjct: 421 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY 480
Query: 441 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN 500
SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN GFAAFGQTKPVVTPFGQVAAAGVSSN
Sbjct: 481 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN--GFAAFGQTKPVVTPFGQVAAAGVSSN 538
Query: 501 PFMTGAPTGQFPTGSSSTNPFL 522
PFMTGAPTGQFPTGSSSTNPFL
Sbjct: 539 PFMTGAPTGQFPTGSSSTNPFL 560
>gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]
Length = 584
Score = 846 bits (2186), Expect = 0.0
Identities = 464/590 (78%), Positives = 477/590 (80%), Gaps = 74/590 (12%)
Query: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
Sbjct: 1 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN 60
Query: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
Sbjct: 61 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK 120
Query: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
Sbjct: 121 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ 180
Query: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNA 240
SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA ++A NA
Sbjct: 181 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSA--NA 238
Query: 241 NFAHFDNFPKSS-SADFGTFNTS-----QSHQTASAVSKVS------TNKAGLQ------ 282
+FA+FD F +SS S++FG F T+ Q TA + S T+ LQ
Sbjct: 239 DFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGS 298
Query: 283 TADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVS-------------------- 322
A A A+ DN F D G+ F T+ S VS
Sbjct: 299 AASVNANFAHFDN-FPKSSSADFGT-FNTSQSHQTASAVSKVSTNKAGLQTADKYAALAN 356
Query: 323 ------------------------------VPSQSSASSDKYAALAELDSVFSSAATSSN 352
VPSQSSASSDKYAALAELDSVFSSAATSSN
Sbjct: 357 LDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSN 416
Query: 353 AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ 412
AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ
Sbjct: 417 AYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQ 476
Query: 413 TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN 472
TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN
Sbjct: 477 TNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPN 536
Query: 473 GAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
GFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
Sbjct: 537 --GFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 584
>gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]
Length = 481
Score = 297 bits (760), Expect = 2e-80
Identities = 211/510 (41%), Positives = 250/510 (49%), Gaps = 85/510 (16%)
Query: 26 NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHG 85
NR CF+C QRG TYV++TVGSFVCT+CSG LRGLNPPHRVKSISMTTFT+ E+ FLQ G
Sbjct: 44 NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRG 103
Query: 86 NEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISG 145
NEVC++IWLGLFD R+S +PD RDPQKVKEFLQEKYEKKRWYVPP+Q K S
Sbjct: 104 NEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS--- 160
Query: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQ-----------EK 194
+S S PE KPL++LLGD AP+L + T SQ ++ Q +K
Sbjct: 161 ASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKK 220
Query: 195 KQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFPKS-SS 253
DLL+D+G D FAAP FA F F GG S FA+FD F SS
Sbjct: 221 ASTDLLADIGGDPFAAPQMAPA----FAAFPAF----GGQTPS-QGGFANFDAFSSGPSS 271
Query: 254 ADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTG 313
+ FG+ + +A Q A G QG+ FG T
Sbjct: 272 SVFGSLPPA--------------GQASFQAQPTPA-------------GSSQGTPFGATP 304
Query: 314 KAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVAS 373
AP S+ S A S+F A G VP + S
Sbjct: 305 LAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMA------------------GQVPPLQS 346
Query: 374 AQTQPAS-SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPT 432
SS FGA TNPF A A S STNPFQ N A FG +S
Sbjct: 347 VTMGGGGGSSTGLAFGAF--TNPFTAPAAQSPLPSTNPFQPNGL-APGPGFGMSS----A 399
Query: 433 GFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQV 492
G G P +F+ SF P FP Q T QQ NG+ F G K P Q
Sbjct: 400 GPGFPQAVPPTGAFASSFPAPLFPPQ------TPLVQQQNGSSFGDLGSAKLGQRPLSQ- 452
Query: 493 AAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
AG+S+NPFMTG + F + +TNPFL
Sbjct: 453 -PAGISTNPFMTGPSSSPFASKPPTTNPFL 481
>gi|113204622 stromal membrane-associated GTPase-activating protein
1 isoform A [Homo sapiens]
Length = 467
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/156 (27%), Positives = 81/156 (51%), Gaps = 14/156 (8%)
Query: 7 RKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRV 65
+K E+H +L + N+ C DC+ +GP + + +G F+C C+G R L RV
Sbjct: 11 QKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRV 70
Query: 66 KSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDP---QKVKEFLQEKYE 122
KS+++ +T ++I+ +Q GN + ++ ++ +FR P Q V+ F+++KYE
Sbjct: 71 KSVNLDQWTAEQIQCMQDMGNTKARLLY------EANLPENFRRPQTDQAVEFFIRDKYE 124
Query: 123 KKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVK 158
KK++Y +A + S S + S+P ++
Sbjct: 125 KKKYY----DKNAIAITNISSSDAPLQPLVSSPSLQ 156
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 70.9 bits (172), Expect = 3e-12
Identities = 38/125 (30%), Positives = 70/125 (56%), Gaps = 10/125 (8%)
Query: 7 RKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRV 65
+K E+H +L + N+ C DC+ +GP + + +G F+C C+G R L RV
Sbjct: 11 QKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRV 70
Query: 66 KSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDP---QKVKEFLQEKYE 122
KS+++ +T ++I+ +Q GN + ++ ++ +FR P Q V+ F+++KYE
Sbjct: 71 KSVNLDQWTAEQIQCMQDMGNTKARLLY------EANLPENFRRPQTDQAVEFFIRDKYE 124
Query: 123 KKRWY 127
KK++Y
Sbjct: 125 KKKYY 129
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 69.7 bits (169), Expect = 6e-12
Identities = 65/275 (23%), Positives = 118/275 (42%), Gaps = 47/275 (17%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
K +++ +L ++ N+ C DC +GP + + +G F+C C+G R L RVK
Sbjct: 7 KDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVK 66
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPD-FRDPQ---KVKEFLQEKYE 122
S+++ +TQ++I+ +Q+ GN +++ + +P+ FR PQ V+ F+++KYE
Sbjct: 67 SVNLDQWTQEQIQCMQEMGNGKANRLY-------EAYLPETFRRPQIDPAVEGFIRDKYE 119
Query: 123 KKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVK--------------------PLKS 162
KK++ +++ + + + PE K P KS
Sbjct: 120 KKKYM---DRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKS 176
Query: 163 LLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFA 222
+AP + L + + S+ +K DLL+ + P+P S+ +
Sbjct: 177 SPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLA-------SVPSPSSSGSRKVV 229
Query: 223 NFAHFNSHAGGSAASVNANFAHFDNFPKSSSADFG 257
+ GSA SV N F P S S + G
Sbjct: 230 G----SMPTAGSAGSVPENLNLFPE-PGSKSEEIG 259
Score = 30.8 bits (68), Expect = 3.1
Identities = 37/157 (23%), Positives = 55/157 (35%), Gaps = 20/157 (12%)
Query: 357 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 416
+S+ S V G++P SA + P + ++ G+ + S+ S QT
Sbjct: 221 SSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGS-QTPQM 279
Query: 417 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGF 476
A A M+ PT + + + P S GS P A QP +G
Sbjct: 280 PTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVA----------QPGASGM 329
Query: 477 AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPT 513
A P+ P G + S M G P G T
Sbjct: 330 VA-----PMAMPAGYMGGMQAS----MMGVPNGMMTT 357
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 67.8 bits (164), Expect = 2e-11
Identities = 100/374 (26%), Positives = 138/374 (36%), Gaps = 54/374 (14%)
Query: 130 PEQAKVVASVHASISGS---SASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGR 186
P + +S S SGS +ASSTSS+ G S+P S +P G+
Sbjct: 1754 PAFGQPASSTPTSTSGSVFGAASSTSSSSSFS-----FGQSSPNTGGGLFGQSNAPAFGQ 1808
Query: 187 SQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSA---ASVNANFA 243
S G Q F S AA +T+ +F + F S GS A+
Sbjct: 1809 SPGFGQGGSVFGGTS-------AATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIV 1861
Query: 244 HFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGG 303
SS + FG+ NT + S + K A+K N FS+ GG
Sbjct: 1862 FGQQSSSSSGSVFGSGNTGRGGGFFSGLG----GKPSQDAANK--------NPFSSASGG 1909
Query: 304 DQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELD--SVFSSAATS--SNAYTSTSN 359
FG+T + ++ + ++ E FSS S S + +S
Sbjct: 1910 -----FGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSP 1964
Query: 360 ASSNVFGTVPVVASAQT---QPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR 416
+ FG PV S T P VPA FG+ P+ + + G V F
Sbjct: 1965 NKTGGFGAAPVFGSPPTFGGSPGFGGVPA-FGSAPAFTSPLGSTGGKV------FGEGTA 2017
Query: 417 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGF 476
A+A FG S S T FGT A + PT S S Q F Q+ + FS +G G
Sbjct: 2018 AASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQS-----SGFSGFGSGTGG 2072
Query: 477 AAFGQTKPVVTPFG 490
+FG V FG
Sbjct: 2073 FSFGSNNSSVQGFG 2086
Score = 58.5 bits (140), Expect = 1e-08
Identities = 101/404 (25%), Positives = 143/404 (35%), Gaps = 61/404 (15%)
Query: 130 PEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQG 189
P +V AS S+ G ST+ST P S G S+P GT + V G++
Sbjct: 1672 PVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAF----GTTAPG-VFGQTT- 1725
Query: 190 QQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFP 249
F S G +A + S + F++ F A + S
Sbjct: 1726 -------FGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTS------------ 1766
Query: 250 KSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQG---GDQG 306
+S + FG AS+ S S+ G + + L N + GQ G G
Sbjct: 1767 -TSGSVFGA---------ASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGG 1816
Query: 307 SGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAY--TSTSNASSNV 364
S FG T A + S S AS + SVF AA++ +S++S +V
Sbjct: 1817 SVFGGTSAATTTAATSGFSFCQASG---FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSV 1873
Query: 365 FGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFG 424
FG+ P+ A + NPF +A+G +++T+ + A TFG
Sbjct: 1874 FGSGNTGRGGGFFSGLGGKPSQDAA--NKNPFSSASGGFGSTATSNTSNLFGNSGAKTFG 1931
Query: 425 TASMSMPTGFGTPAPYSLPTSFSGS-------FQQP----AFPAQAAFPQQTAFSQQPNG 473
+ S FG P +S GS F P F A F F P
Sbjct: 1932 GFASS---SFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGF 1988
Query: 474 AGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSS 517
G AFG +P G + G A G F GSSS
Sbjct: 1989 GGVPAFGSAPAFTSPLG--STGGKVFGEGTAAASAGGFGFGSSS 2030
Score = 55.1 bits (131), Expect = 2e-07
Identities = 54/174 (31%), Positives = 77/174 (44%), Gaps = 16/174 (9%)
Query: 312 TGKAPVGSVVS--VPSQSSASSDKYAALAELDSVFSS--AATSSNAYTSTSNASSNVFGT 367
T P+ S + V SA + + + SVF+ AA+SS+A+ +N ++
Sbjct: 1611 TSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSA 1670
Query: 368 VPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA-ATFGTA 426
PV Q A+S+ P+ FG + AAA P V+SS F + A G TA FG
Sbjct: 1671 TPVFG----QVAASTAPSLFGQQTGSTASTAAATPQVSSS--GFSSPAFGTTAPGVFGQT 1724
Query: 427 SMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFG 480
+ + FG A S + F SF QP F + AF Q S P + FG
Sbjct: 1725 TFGQASVFGQSAS-SAASVF--SFSQPGFSSVPAFGQPA--SSTPTSTSGSVFG 1773
Score = 53.5 bits (127), Expect = 5e-07
Identities = 79/322 (24%), Positives = 127/322 (39%), Gaps = 37/322 (11%)
Query: 213 PQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTA---- 268
P +T+T++ A F + GS+ ++ F S+ +F + Q++ T
Sbjct: 1400 PAATSTSSTAVFGSLPVTSAGSSGVIS-----FGGTSLSAGKTSFSFGSQQTNSTVPPSA 1454
Query: 269 ----SAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVP 324
+A + + T+ L ++ SAG+ ++ + K P S VS
Sbjct: 1455 PPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEK-PGDSEVSAS 1513
Query: 325 SQSSASSDKYAALAELDSVFSSAATSSN--AYTSTSNASSNVFGTVPVVASAQTQPASSS 382
+ S + A L + S + A + SN+ + T V SA+ PA++
Sbjct: 1514 AASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTG 1573
Query: 383 VP-APFGATPSTNPF----VAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTP 437
VP A A P + F A + SS P +T T S+ P
Sbjct: 1574 VPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVET-SSTPIASSTTSIVAPGPSAEA 1632
Query: 438 APYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTP-FGQVAAAG 496
A + TS S F QP PA ++ +AF+Q N T P TP FGQVAA
Sbjct: 1633 AAFGTVTSGSSVFAQP--PAASS---SSAFNQLTNNTA------TAPSATPVFGQVAA-- 1679
Query: 497 VSSNPFMTGAPTGQFPTGSSST 518
S+ P + G TG + +++T
Sbjct: 1680 -STAPSLFGQQTGSTASTAAAT 1700
Score = 38.9 bits (89), Expect = 0.012
Identities = 69/268 (25%), Positives = 102/268 (38%), Gaps = 43/268 (16%)
Query: 203 LGSDIFAAPA--PQSTATANFANFA-----------HFNSHAGGSAASVNANFAHFDNFP 249
L + AAPA P S+ A A F+ F S + S+A+V + +
Sbjct: 447 LDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGS 506
Query: 250 KSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGF 309
SS A G S S V +KA L + +A FS G G + +
Sbjct: 507 DSSKAAPGP--------GPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLE 558
Query: 310 GTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVP 369
T P S ++ + S A L F++AATS+ +S S + F
Sbjct: 559 STP--VPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPF---- 612
Query: 370 VVASAQTQPASS---SVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTA 426
S+ ++PA+S S P P A PS+ P ++ PS + R A ++
Sbjct: 613 ---SSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPS---------PSGRSAQGSSSPVP 660
Query: 427 SMSMPTGFGTPAPYSLPTSFSGSFQQPA 454
SM + TP P + P S QPA
Sbjct: 661 SMVQKSPRITP-PAAKPGSPQAKSLQPA 687
Score = 38.5 bits (88), Expect = 0.015
Identities = 75/295 (25%), Positives = 109/295 (36%), Gaps = 44/295 (14%)
Query: 197 FDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNA--NFAHFDNFPKSSSA 254
F +++ S F A + +T + F+S GGS S A + +S+
Sbjct: 1225 FGIITPTPSSNFTAAQGATPSTKESSQPDAFSS-GGGSKPSYEAIPESSPPSGITSASNT 1283
Query: 255 DFGTFNTSQSHQTASAVSKVSTNKAGLQTA-DKYAALANLDNI-------FSAGQGGDQG 306
G S S A + + +ST + L+T K L ++ FS + G
Sbjct: 1284 TPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQAD 1343
Query: 307 SGFGTTGKAPVGSVVS--------VPSQSSASSDKYAALAELDSVFSSAATSSNAY-TST 357
T KA S+ S VPS + ++ V SSA T+S A +T
Sbjct: 1344 DSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAAT 1403
Query: 358 SNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARG 417
S +S+ VFG++PV T SS V + G + S + G +ST P
Sbjct: 1404 STSSTAVFGSLPV-----TSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVP------- 1451
Query: 418 ATAATFGTASMSMPTGFGTPAPYSLPT----SFSGSFQQPAFPAQAAFPQQTAFS 468
S PT TP P S PT S S P+ P A + A S
Sbjct: 1452 --------PSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATS 1498
>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
isoform a [Homo sapiens]
Length = 406
Score = 66.2 bits (160), Expect = 7e-11
Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 23/242 (9%)
Query: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
Query: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
Query: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
Query: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVN 239
+ VG +KK+ D L++ S +++ + +T + FA+ A + GS AS
Sbjct: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQASQK 239
Query: 240 AN 241
A+
Sbjct: 240 AS 241
>gi|6806913 centaurin, alpha 1 [Homo sapiens]
Length = 374
Score = 65.9 bits (159), Expect = 9e-11
Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 14/116 (12%)
Query: 24 PHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQK 83
P N +C DC P + + T+G F+C SCSG R + +VKS+ + + + ++EF+
Sbjct: 16 PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMAS 75
Query: 84 HGNEVCKQIWLGLFDDRSSAIPDF------RDPQKVKE-FLQEKYEKKRWYVPPEQ 132
HGN+ + + S +P F D Q ++E +++ KYE++ + P +Q
Sbjct: 76 HGNDAARARF-------ESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQ 124
>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
isoform b [Homo sapiens]
Length = 414
Score = 65.1 bits (157), Expect = 2e-10
Identities = 61/238 (25%), Positives = 106/238 (44%), Gaps = 23/238 (9%)
Query: 15 KMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTF 73
K+L+++ N CF+C P +V++T G ++C CSG RGL V+S++M +
Sbjct: 8 KVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKW 67
Query: 74 TQQEIEFLQKHGNEVCKQI----------WLGLFDDRSSAIPDFRDP----QKVKEFLQE 119
E+E ++ GN ++ W S A FRD + +E+ E
Sbjct: 68 KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127
Query: 120 KYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPS 179
+ W PP+ + + VH +SG S T+S+ K + L D + +G
Sbjct: 128 SSPAQNW-TPPQPRTLPSMVH-RVSGQPQSVTASSD--KAFEDWLNDDLGSYQGAQG--- 180
Query: 180 QSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAAS 237
+ VG +KK+ D L++ S +++ + +T + FA+ A + GS AS
Sbjct: 181 -NRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEGATKFGSQAS 237
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 59.3 bits (142), Expect = 8e-09
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +R+M G H C DC+ + P + ++ +G+ +C CSG R L RV+
Sbjct: 553 QSEAMALQSIRNMRGNSH---CVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 609
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRW 126
S+ + + + I+ + GNE+ +W R+ D +K + +++ KYE+K +
Sbjct: 610 SLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEK-ERWIRAKYEQKLF 668
Query: 127 YVP 129
P
Sbjct: 669 LAP 671
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 59.3 bits (142), Expect = 8e-09
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +R+M G H C DC+ + P + ++ +G+ +C CSG R L RV+
Sbjct: 606 QSEAMALQSIRNMRGNSH---CVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 662
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRW 126
S+ + + + I+ + GNE+ +W R+ D +K + +++ KYE+K +
Sbjct: 663 SLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEK-ERWIRAKYEQKLF 721
Query: 127 YVP 129
P
Sbjct: 722 LAP 724
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 56.6 bits (135), Expect = 5e-08
Identities = 76/275 (27%), Positives = 102/275 (37%), Gaps = 50/275 (18%)
Query: 256 FGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKA 315
F N S S + A S G T+ +A +F S FG T ++
Sbjct: 1190 FSFLNNSSSSSSTPATS-AGGGIFGSSTSSSNPPVATF--VFGQSSNPVSSSAFGNTAES 1246
Query: 316 PVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS----------TSNASSNVF 365
+ S ++ A VF A+S+N TS +S SS VF
Sbjct: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVF 1306
Query: 366 GTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGT 425
GT P SA PA FGA T F + G AS NP + ++ A F T
Sbjct: 1307 GTGPSAPSAS--------PA-FGAN-QTPTFGQSQG---ASQPNPPGFGSISSSTALFPT 1353
Query: 426 ASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPV 485
S P FGT + S P F QQ P+Q+AF T PN + FG +
Sbjct: 1354 GSQPAPPTFGTVSSSSQPPVFG---QQ---PSQSAFGSGTT----PNSSSAFQFGSS--- 1400
Query: 486 VTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 520
T F F +P+G F G++S+ P
Sbjct: 1401 TTNFN-----------FTNNSPSGVFTFGANSSTP 1424
Score = 38.9 bits (89), Expect = 0.012
Identities = 74/304 (24%), Positives = 110/304 (36%), Gaps = 37/304 (12%)
Query: 246 DNFPKSSSADFGTFNTSQSHQTASAVSKVST--NKAGLQTADKYAALANLDNIFSAGQGG 303
+ PKSSSA F +F T + T + + + T NK+ A++
Sbjct: 1012 EELPKSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEA 1070
Query: 304 DQGSGFGTTGKAPVGSV--VSVPSQS-----SASSDKYAALAELDSVFSSAATS------ 350
+ T G G+V S+PS S + + VF A +
Sbjct: 1071 KKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQ 1130
Query: 351 ------SNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSV 404
++ T N+S + F S + + FGA ST AA P
Sbjct: 1131 PVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF 1190
Query: 405 ASSTNPFQTNARGATAATFG-----TASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQA 459
+ N +++ AT+A G T+S + P S P S S +F A++
Sbjct: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS-SSAFGN---TAES 1246
Query: 460 AFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMT-GAPTGQFPTGSSST 518
+ Q FSQ + A T VTPF V G SSN T G G T SS+
Sbjct: 1247 STSQSLLFSQD---SKLATTSSTGTAVTPF--VFGPGASSNNTTTSGFGFGATTTSSSAG 1301
Query: 519 NPFL 522
+ F+
Sbjct: 1302 SSFV 1305
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 55.8 bits (133), Expect = 9e-08
Identities = 77/286 (26%), Positives = 114/286 (39%), Gaps = 40/286 (13%)
Query: 249 PKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSG 308
PK S FGT NTS S A A S S + TA + + G G
Sbjct: 435 PKQSFL-FGTQNTSPSSPAAPAASSASPMFKPIFTAPP-----------KSEKEGPTPPG 482
Query: 309 FGTTGKAPVGSVVSVPSQSSASSDKY----------AALAELDSVFSSAATSSNAYTSTS 358
T AP S S+P+ +S ++ + A++ F T + A T+T+
Sbjct: 483 PSVTATAPSSS--SLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA 540
Query: 359 ---NASSNVFGTVPVVASAQTQPASSSVPA-PFGATPSTNPFVAAAGPSVASSTNPFQTN 414
++ V + SA S+S PA FG ++ V+ + +++ PF
Sbjct: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
Query: 415 ARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGA 474
A A+AA+F T +M FG P +LPT+ + + + P A P T+ S A
Sbjct: 601 APQASAASF-TPAMGSIFQFGKPP--ALPTTTTVTTFSQSLP--TAVPTATSSS----AA 651
Query: 475 GFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP 520
F+ FG T P SN T PT P GSS+ +P
Sbjct: 652 DFSGFGSTLATSAPATSSQPTLTFSN---TSTPTFNIPFGSSAKSP 694
Score = 55.8 bits (133), Expect = 9e-08
Identities = 61/211 (28%), Positives = 93/211 (44%), Gaps = 23/211 (10%)
Query: 312 TGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSN--VFGTVP 369
TG A S V+ + +S S+D + A + S +++S + TST+ A+S +FG P
Sbjct: 544 TGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-AP 602
Query: 370 VVASAQTQPASSSV-----PAPFGATPSTNPFVAAAGPSV--ASSTNPFQTNARGATAAT 422
++A PA S+ P T + F + +V A+S++ + G+T AT
Sbjct: 603 QASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLAT 662
Query: 423 FGTASMSMPT----GFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAA 478
A+ S PT TP +++P S P++P P A QP GA
Sbjct: 663 SAPATSSQPTLTFSNTSTPT-FNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGA---- 717
Query: 479 FGQTKPVVTP-FGQVAAAGVSSNPFMTGAPT 508
KP +TP FG G S+ P APT
Sbjct: 718 ---AKPALTPSFGSSFTFGNSAAPAPATAPT 745
Score = 49.3 bits (116), Expect = 9e-06
Identities = 97/398 (24%), Positives = 140/398 (35%), Gaps = 55/398 (13%)
Query: 129 PPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQS-PVVGRS 187
PP + A + + + T++ P L S AP + T S S P G
Sbjct: 515 PPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG-- 572
Query: 188 QGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDN 247
F + S S + +T+TA A+ SAAS
Sbjct: 573 ---------FGINSVSSSSVST-----TTSTATAASQPFLFGAPQASAASFTPAMGSIFQ 618
Query: 248 FPKSSSADFGTFNTSQSHQTASAVSKVSTNKA------GLQTADKYAALANLDNI-FSAG 300
F K + T T+ S +AV +++ A G A A ++ + FS
Sbjct: 619 FGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNT 678
Query: 301 QGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNA 360
FG++ K+P+ PS A+ AE ++ + S
Sbjct: 679 STPTFNIPFGSSAKSPL------PSYPGANPQPAFGAAE-----GQPPGAAKPALTPSFG 727
Query: 361 SSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATA 420
SS FG SA PA++ PAP ST V A P+ P Q GAT
Sbjct: 728 SSFTFGN-----SAAPAPATAPTPAP----ASTIKIVPAHVPT------PIQPTFGGATH 772
Query: 421 ATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFG 480
+ FG + + + FG PA S +F GS +F A + +G+ + FG
Sbjct: 773 SAFGLKATA--SAFGAPA--SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFG 828
Query: 481 QTKPVVTPFGQVAA-AGVSSNPFMTGAPTGQFPTGSSS 517
T P FG AA AG S P TG+ S
Sbjct: 829 STTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFS 866
Score = 43.1 bits (100), Expect = 6e-04
Identities = 57/216 (26%), Positives = 81/216 (37%), Gaps = 29/216 (13%)
Query: 320 VVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 379
++ PS A+ K + ++ ATS+ S + S +FGT S+ PA
Sbjct: 399 LIPAPSMVPATDTKAPPTLQAETATKPQATSA---PSPAPKQSFLFGTQNTSPSSPAAPA 455
Query: 380 SSSVPAPF-------------GATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTA 426
+SS F G TP P V A PS SS+ P T+ TA TF
Sbjct: 456 ASSASPMFKPIFTAPPKSEKEGPTPP-GPSVTATAPS--SSSLPTTTST---TAPTFQPV 509
Query: 427 SMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVV 486
SM G PA LP F F+Q PA A F+ + A +
Sbjct: 510 FSSM----GPPASVPLPAPF---FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPS 562
Query: 487 TPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
T A G N + + + T ++++ PFL
Sbjct: 563 TDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R RV+
Sbjct: 461 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVR 517
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GNE+ IW G + P + ++ KE +++ KYE+K
Sbjct: 518 SLELDDWPVELRKVMSSIGNELANSIWEG--SSQGQTKPSIKSTREEKEWWIRSKYEEKL 575
Query: 126 WYVP 129
+ P
Sbjct: 576 FLAP 579
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 55.5 bits (132), Expect = 1e-07
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R RV+
Sbjct: 461 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVR 517
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GNE+ IW G + P + ++ KE +++ KYE+K
Sbjct: 518 SLELDDWPVELRKVMSSIGNELANSIWEG--SSQGQTKPSIKSTREEKEWWIRSKYEEKL 575
Query: 126 WYVP 129
+ P
Sbjct: 576 FLAP 579
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/124 (26%), Positives = 63/124 (50%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R L RV+
Sbjct: 438 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 494
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GN++ IW G R+ P + ++ KE +++ KYE+K
Sbjct: 495 SLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTK--PTEKSTREEKERWIRSKYEEKL 552
Query: 126 WYVP 129
+ P
Sbjct: 553 FLAP 556
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 54.7 bits (130), Expect = 2e-07
Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 26 NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTTFTQQEIEFLQKH 84
N C DCD P + ++ +G+ +C CSG R L RV+S+ + + + + +
Sbjct: 674 NSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAM 733
Query: 85 GNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVP 129
GN + +W G S PD +K + +++ KYE+K + P
Sbjct: 734 GNALANSVWEGALGGYSKPGPDACREEK-ERWIRAKYEQKLFLAP 777
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 54.3 bits (129), Expect = 3e-07
Identities = 32/124 (25%), Positives = 60/124 (48%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R L RV+
Sbjct: 325 QSEAMALQSIQNMRGNSH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVR 381
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GN++ IW G + P ++ KE +++ KYE K
Sbjct: 382 SLELDDWPVELRKVMSSIGNDLANSIWEG--SSQGQTKPSIESTREEKERWIRSKYEHKL 439
Query: 126 WYVP 129
+ P
Sbjct: 440 FLAP 443
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 54.3 bits (129), Expect = 3e-07
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG R L P RV+
Sbjct: 461 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVR 517
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + N++ IW G + P + ++ KE +++ KYE+K
Sbjct: 518 SLELDDWPVELRKVMSSIVNDLANSIWEG--SSQGQTKPSEKSTREEKERWIRSKYEEKL 575
Query: 126 WYVP 129
+ P
Sbjct: 576 FLAP 579
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 53.9 bits (128), Expect = 3e-07
Identities = 31/118 (26%), Positives = 60/118 (50%), Gaps = 7/118 (5%)
Query: 14 LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISMTT 72
L+ +++M G H C DC+ + P + ++ +G +C CSG R L RV+S+ +
Sbjct: 444 LQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDD 500
Query: 73 FTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKRWYVP 129
+ + + + GN++ IW G + P + ++ KE +++ KYE+K + P
Sbjct: 501 WPVELRKVMSSIGNDLANSIWEG--SSQGQTKPSEKSTREEKERWIRSKYEEKLFLAP 556
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 53.5 bits (127), Expect = 5e-07
Identities = 62/216 (28%), Positives = 95/216 (43%), Gaps = 25/216 (11%)
Query: 312 TGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSN--VFGTVP 369
TG A S V+ + +S S+D + A + S +++S + TST+ A+S +FG P
Sbjct: 393 TGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-AP 451
Query: 370 VVASAQTQPASSSV-----PAPFGATPSTNPFVAAAGPSV--ASSTNPFQTNARGATAAT 422
++A PA S+ P T + F + +V A+S++ + G+T AT
Sbjct: 452 QASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLAT 511
Query: 423 FGTASMSMPT----GFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAA 478
A+ S PT TP +++P S P++P P A QP GA
Sbjct: 512 SAPATSSQPTLTFSNTSTPT-FNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGA---- 566
Query: 479 FGQTKPVVTP-FGQVAAAGVSSNPFMTGAPTGQFPT 513
KP +TP FG G S+ P APT P+
Sbjct: 567 ---AKPALTPSFGSSFTFGNSAAP--AAAPTPAPPS 597
Score = 48.5 bits (114), Expect = 1e-05
Identities = 102/440 (23%), Positives = 157/440 (35%), Gaps = 62/440 (14%)
Query: 130 PEQAKVVASVHASISGSSASSTSS-TPEVKPL------KSLLGDSAPTLHLNKGTPSQSP 182
P+Q+ + + + S S +A + SS +P KP+ G + P ++ PS S
Sbjct: 284 PKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSS 343
Query: 183 V-VGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQST---ATANFANFAHFNSHAGGSAASV 238
+ S + F + S AP + T ATA F A ++A
Sbjct: 344 LPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVA 403
Query: 239 NANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFS 298
A P + SA F + ++S+VS ++ + A F+
Sbjct: 404 PITSAS----PSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFT 459
Query: 299 AGQGGDQGSGFGTTGKAPVGSVVSVPSQS------SASSDKYAALAELDSVF--SSAATS 350
G FG P + V+ SQS +A+S A + S S+ ATS
Sbjct: 460 PAMGSI--FQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATS 517
Query: 351 SNAYTSTSNASSNVFGTV------------------PVVASAQTQPASSSVPAPFGATPS 392
S + SN S+ F P +A+ QP ++ PA + S
Sbjct: 518 SQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGS 577
Query: 393 TNPFVAAAGPSVASST--------------NPFQTNARGATAATFGTASMSMPTGFGTPA 438
+ F +A P+ A + P Q GAT + FG + + + FG PA
Sbjct: 578 SFTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATA--SAFGAPA 635
Query: 439 PYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAA-AGV 497
S +F GS +F A + +G+ + FG T P FG AA AG
Sbjct: 636 --SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGS 693
Query: 498 SSNPFMTGAPTGQFPTGSSS 517
S P TG+ S
Sbjct: 694 GSFGINVATPGSSATTGAFS 713
Score = 43.5 bits (101), Expect = 5e-04
Identities = 57/216 (26%), Positives = 82/216 (37%), Gaps = 29/216 (13%)
Query: 320 VVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 379
++ PS A+ K + ++ ATS+ S + S +FGT S+ PA
Sbjct: 248 LIPAPSMVPATDTKAPPTLQAETTTKPQATSA---PSPAPKQSFLFGTQNTSPSSPAAPA 304
Query: 380 SSSVPAPF-------------GATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTA 426
+SS F G TP P V+A PS SS+ P T+ TA TF
Sbjct: 305 ASSASPMFKPIFTAPPKSEKEGPTPP-GPSVSATAPS--SSSLPTTTST---TAPTFQPV 358
Query: 427 SMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVV 486
SM G PA LP F F+Q PA A F+ + A +
Sbjct: 359 FSSM----GPPASVPLPAPF---FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPS 411
Query: 487 TPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522
T A G N + + + T ++++ PFL
Sbjct: 412 TDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 447
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 53.5 bits (127), Expect = 5e-07
Identities = 69/311 (22%), Positives = 126/311 (40%), Gaps = 14/311 (4%)
Query: 138 SVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQF 197
S AS + +S SST+S+ S + T+ T + S S G
Sbjct: 159 SSEASTATNSESSTTSSGASTATNS----ESSTVSSRASTATNSESSTTSSGASTATNSE 214
Query: 198 DLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFPKSSSADFG 257
+ G+ A + ST ++ + + S S A N + ++S+ G
Sbjct: 215 SRTTSNGAGT-ATNSESSTTSSGASTATNSESSTPSSGAGTATN-----SESSTTSSGAG 268
Query: 258 TFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTT--GKA 315
T S+S +S +S V+ +++ ++ A + + S+G S TT G +
Sbjct: 269 TATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328
Query: 316 PVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQ 375
+ S + S AS+ + + S S+A S ++ TS+ +++ + V + A
Sbjct: 329 TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAS 388
Query: 376 TQPASSSVPAPFGATPSTNPFVAAAGPSVASSTN-PFQTNARGATAATFGTASMSMPTGF 434
T S S GA+ +TN + +++TN T + GA AT +S++ G
Sbjct: 389 TATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVT-SAGS 447
Query: 435 GTPAPYSLPTS 445
GT A + T+
Sbjct: 448 GTAALTGMHTT 458
Score = 52.0 bits (123), Expect = 1e-06
Identities = 74/359 (20%), Positives = 144/359 (40%), Gaps = 23/359 (6%)
Query: 137 ASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQ 196
+S +S + ++ +S SSTP + DS+ T + S+ +
Sbjct: 110 SSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSE 169
Query: 197 FDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFPKSSSADF 256
S S + + ++ A+ A + ++ + G++ + N+ +++S
Sbjct: 170 SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSE-------SRTTSNGA 222
Query: 257 GTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAP 316
GT S+S T+S S + +++ ++ A + + S+G G S T
Sbjct: 223 GTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSG- 281
Query: 317 VGSVVSVPSQSSASSDKYAALAELDSVFSSAAT---SSNAYTST--SNASSNVFGTVPVV 371
+ +V + S + +S A +E + S A T S ++ TS+ S A+++ T
Sbjct: 282 ISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSG 341
Query: 372 ASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT---AATFGTASM 428
AS T SS+ + GA+ +TN +G S SS TN+ +T A+ T S
Sbjct: 342 ASTATNSESSTTSS--GASTATN-----SGSSTTSSGTSTATNSESSTVSSGASTATTSE 394
Query: 429 SMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVT 487
S T G + +S S A ++++ A + +G+ + G +T
Sbjct: 395 SSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALT 453
Score = 43.5 bits (101), Expect = 5e-04
Identities = 60/252 (23%), Positives = 113/252 (44%), Gaps = 18/252 (7%)
Query: 201 SDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFPKSSSADFGTFN 260
++ GS + ++ A STAT N + +G S A+++ + + ++++F T +
Sbjct: 31 ANTGSSVISSGA--STAT----NSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTS 84
Query: 261 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 320
+ S T S S VS+ + T + + ++ + + + SG T + S
Sbjct: 85 SGISTATNSEFSTVSSG-ISIATNSESSTTSSGASTATNSESSTPSSGASTATNSD-SST 142
Query: 321 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTST--SNASSNVFGTVPVVASAQTQP 378
S + ++ +SD +E S+A S ++ TS+ S A+++ TV AS T
Sbjct: 143 TSSGASTATNSDSSTTSSEA----STATNSESSTTSSGASTATNSESSTVSSRASTATNS 198
Query: 379 ASSSVPAPFGATPSTNPFVAAAGPSVASSTN-PFQTNARGATAATFGTASMSMPTGFGTP 437
SS+ + GA+ +TN ++TN T + GA+ AT + S + +G GT
Sbjct: 199 ESSTTSS--GASTATNSESRTTSNGAGTATNSESSTTSSGASTAT-NSESSTPSSGAGTA 255
Query: 438 APYSLPTSFSGS 449
T+ SG+
Sbjct: 256 TNSESSTTSSGA 267
Score = 30.8 bits (68), Expect = 3.1
Identities = 36/175 (20%), Positives = 68/175 (38%), Gaps = 10/175 (5%)
Query: 347 AATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVAS 406
AAT+SN ++++N S+V + AS T SS + + V + G S+ +
Sbjct: 20 AATNSNETSTSANTGSSVISS---GASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 407 STNPFQTNARGATAAT---FGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQ 463
++ F T + G + AT F T S + + + + + + + + + P+ A
Sbjct: 77 NSE-FHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGA--- 132
Query: 464 QTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSST 518
TA + + A T + A+ +S T + SST
Sbjct: 133 STATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESST 187
>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
isoform 2 [Homo sapiens]
Length = 472
Score = 52.8 bits (125), Expect = 8e-07
Identities = 46/173 (26%), Positives = 74/173 (42%), Gaps = 31/173 (17%)
Query: 14 LKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVKSISM-T 71
L + + + +P N+ CFDC + P++ ++T G F+C CSGS R L ++S + +
Sbjct: 10 LTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDS 69
Query: 72 TFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPE 131
++ ++ +Q GN +WL S +P P K ++F +V PE
Sbjct: 70 NWSWFQLRCMQVGGN--ASALWLD-----SCVVPPLSPPPKEEDFFAS-------HVSPE 115
Query: 132 QAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVV 184
V + AS +S TS E TL N+G Q P V
Sbjct: 116 ---VSDTAWASAIAEPSSLTSRPVET------------TLENNEGGQEQGPSV 153
>gi|19111150 angiomotin isoform 2 [Homo sapiens]
Length = 675
Score = 52.8 bits (125), Expect = 8e-07
Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 322 SVPSQSSASSDKYAALAELD--SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 379
S ++ S+K AA+A + + ++AAT++ + + ++ + PV +A PA
Sbjct: 454 STQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPA 513
Query: 380 SSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAP 439
+++ P+P A + AA P+ A + A A A A+ ++ PAP
Sbjct: 514 AAAAPSPATAAAT----AAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 569
Query: 440 YSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSS 499
P PA AQA+ P QT Q P A A P TP VA A V +
Sbjct: 570 VPAPALV--PVPAPA-AAQASAPAQT---QAPTSAPAVA---PTPAPTPTPAVAQAEVPA 620
Query: 500 NPFMTGAPTGQFPTGSSSTNP 520
+P TG + S + NP
Sbjct: 621 SP-ATGPGPHRLSIPSLTCNP 640
Score = 33.9 bits (76), Expect = 0.37
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 315 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 374
APV + + + ++ ++ + V +AA + A + S A++ A+A
Sbjct: 476 APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 535
Query: 375 QTQPASSSVPAPFGATPSTNPFV------AAAGPSVASSTNPFQTNARGATAATFGT-AS 427
PA++SV + PS AA P A + P A +A T A
Sbjct: 536 GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 595
Query: 428 MSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQ 464
S P TPAP PT + PA PA P +
Sbjct: 596 TSAPAVAPTPAP--TPTPAVAQAEVPASPATGPGPHR 630
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 52.8 bits (125), Expect = 8e-07
Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 322 SVPSQSSASSDKYAALAELD--SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPA 379
S ++ S+K AA+A + + ++AAT++ + + ++ + PV +A PA
Sbjct: 863 STQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPA 922
Query: 380 SSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAP 439
+++ P+P A + AA P+ A + A A A A+ ++ PAP
Sbjct: 923 AAAAPSPATAAAT----AAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAP 978
Query: 440 YSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSS 499
P PA AQA+ P QT Q P A A P TP VA A V +
Sbjct: 979 VPAPALV--PVPAPA-AAQASAPAQT---QAPTSAPAVA---PTPAPTPTPAVAQAEVPA 1029
Query: 500 NPFMTGAPTGQFPTGSSSTNP 520
+P TG + S + NP
Sbjct: 1030 SP-ATGPGPHRLSIPSLTCNP 1049
Score = 33.9 bits (76), Expect = 0.37
Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 315 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 374
APV + + + ++ ++ + V +AA + A + S A++ A+A
Sbjct: 885 APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAA 944
Query: 375 QTQPASSSVPAPFGATPSTNPFV------AAAGPSVASSTNPFQTNARGATAATFGT-AS 427
PA++SV + PS AA P A + P A +A T A
Sbjct: 945 GQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 1004
Query: 428 MSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQ 464
S P TPAP PT + PA PA P +
Sbjct: 1005 TSAPAVAPTPAP--TPTPAVAQAEVPASPATGPGPHR 1039
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 52.8 bits (125), Expect = 8e-07
Identities = 31/124 (25%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 8 KQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-HRVK 66
+ E L+ +++M G H C DC+ + P + ++ +G +C CSG L RV+
Sbjct: 438 QSEAMALQSIQNMRGNAH---CVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVR 494
Query: 67 SISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKE-FLQEKYEKKR 125
S+ + + + + + GN++ IW G + P + ++ KE +++ KYE+K
Sbjct: 495 SLELDDWPVELRKVMSSIGNDLANSIWEG--SSQGQTKPSEKSTREEKERWIRSKYEEKL 552
Query: 126 WYVP 129
+ P
Sbjct: 553 FLAP 556
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/190 (22%), Positives = 84/190 (44%), Gaps = 17/190 (8%)
Query: 8 KQEEKHLK---MLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPP-H 63
+ +EK LK L+ + +P N C DC P + ++ +G +C CSG R L
Sbjct: 390 ESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFS 449
Query: 64 RVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEK 123
+V+S+++ T+ + ++ + + GN+V +++ + P Q+ + +++ KY +
Sbjct: 450 KVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVE 509
Query: 124 KRW-------YVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKG 176
+++ PPEQ K +S SS S + P + + ++ N
Sbjct: 510 RKFVDKYSISLSPPEQQK------KFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDS 563
Query: 177 TPSQSPVVGR 186
QS GR
Sbjct: 564 GIQQSSDDGR 573
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.123 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,632,218
Number of Sequences: 37866
Number of extensions: 991017
Number of successful extensions: 5292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 336
Number of HSP's that attempted gapping in prelim test: 3950
Number of HSP's gapped (non-prelim): 1175
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.