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Search of human proteins with 205830473
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2
[Homo sapiens]
(602 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 1233 0.0
gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 930 0.0
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 730 0.0
gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] 340 2e-93
gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 288 1e-77
gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] 273 3e-73
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 271 1e-72
gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ... 264 2e-70
gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] 250 3e-66
gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec... 248 9e-66
gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec... 244 2e-64
gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 239 7e-63
gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec... 225 8e-59
gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] 214 1e-55
gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom... 181 2e-45
gi|11225258 myelin associated glycoprotein isoform a precursor [... 139 1e-32
gi|18104957 myelin associated glycoprotein isoform b precursor [... 139 1e-32
gi|13489095 sialoadhesin precursor [Homo sapiens] 99 9e-21
gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] 96 7e-20
gi|157168355 CD22 molecule [Homo sapiens] 89 1e-17
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 77 6e-14
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 77 6e-14
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 77 6e-14
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 75 2e-13
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 75 2e-13
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 75 2e-13
gi|118572606 hemicentin 1 [Homo sapiens] 74 3e-13
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 74 4e-13
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 74 5e-13
gi|109150416 peroxidasin [Homo sapiens] 74 5e-13
>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
sapiens]
Length = 602
Score = 1233 bits (3190), Expect = 0.0
Identities = 602/602 (100%), Positives = 602/602 (100%)
Query: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR
Sbjct: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
Query: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD
Sbjct: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
Query: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN
Sbjct: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
Query: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ
Sbjct: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
Query: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV
Sbjct: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV
Sbjct: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
Query: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV
Sbjct: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
Query: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAGVAALLAFC 480
LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAGVAALLAFC
Sbjct: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAGVAALLAFC 480
Query: 481 SCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGK 540
SCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGK
Sbjct: 481 SCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGK 540
Query: 541 GEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIHTGQPLRGPGFGLQLEREMSGMV 600
GEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIHTGQPLRGPGFGLQLEREMSGMV
Sbjct: 541 GEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIHTGQPLRGPGFGLQLEREMSGMV 600
Query: 601 PK 602
PK
Sbjct: 601 PK 602
>gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo
sapiens]
Length = 698
Score = 930 bits (2404), Expect = 0.0
Identities = 454/455 (99%), Positives = 455/455 (100%)
Query: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR
Sbjct: 1 MVPGQAQPQSPEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPR 60
Query: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD
Sbjct: 61 DGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRD 120
Query: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN
Sbjct: 121 AQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFN 180
Query: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ
Sbjct: 181 WAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQ 240
Query: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV
Sbjct: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV
Sbjct: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRV 360
Query: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV
Sbjct: 361 MVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGV 420
Query: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHW 455
LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH+
Sbjct: 421 LELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHY 455
Score = 382 bits (982), Expect = e-106
Identities = 220/390 (56%), Positives = 251/390 (64%), Gaps = 38/390 (9%)
Query: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
TC + +R G S Q+ + L V Y P++L + +S N + LE GN L V +GQ LRL+
Sbjct: 333 TCRAE-NRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Query: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
C S PPA LSW + + S P P L EL ++ G +TC A++ LGSQ +
Sbjct: 391 CVTHSSPPARLSWTRWGQTVGPSQPSDPGVL--ELPPIQMEHEGEFTCHAQHPLGSQHVS 448
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L LSV YPP+ L S E + L C + +SP L W
Sbjct: 449 LSLSVHYPPQLLGPSCSW------------------EAEGLHCSCSSQASPAPSLRWWLG 490
Query: 407 GQTVGPSQPSDPGVLELPPIQME---------HEG-----EFTCHAQHPLGSQHVSLSLS 452
+ + + S G E+ P H G C A + G+Q S+
Sbjct: 491 EELLEGN--SSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQL 548
Query: 453 VHWKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPI 512
+ KLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPI
Sbjct: 549 LPGKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPI 608
Query: 513 SQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEY 572
SQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEY
Sbjct: 609 SQGHQHECSAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEY 668
Query: 573 SEIKIHTGQPLRGPGFGLQLEREMSGMVPK 602
SEIKIHTGQPLRGPGFGLQLEREMSGMVPK
Sbjct: 669 SEIKIHTGQPLRGPGFGLQLEREMSGMVPK 698
Score = 82.4 bits (202), Expect = 1e-15
Identities = 51/131 (38%), Positives = 72/131 (54%), Gaps = 4/131 (3%)
Query: 333 TCRAE-NRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
TC + +R G S Q+ + L V Y P++L + +S N + LE GN L V +GQ LRL+
Sbjct: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
Query: 391 CVTHSSPPARLSWTRWGQTVGPSQPSDPGVL--ELPPIQMEHEGEFTCHAQHPLGSQHVS 448
C S PPA LSW + + S P P L EL ++ G +TC A++ LGSQ +
Sbjct: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
Query: 449 LSLSVHWKLEH 459
L LSV + E+
Sbjct: 347 LDLSVQYPPEN 357
>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
Length = 697
Score = 730 bits (1885), Expect = 0.0
Identities = 360/444 (81%), Positives = 393/444 (88%), Gaps = 2/444 (0%)
Query: 14 LLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
+LLPLLL L GS D + ++VQ V VPEGLC+ V C+ SYPR W ST AYGYW
Sbjct: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
Query: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
FK T GAPVATN+QSREVEMSTR RFQLTGDP KG+CSLVIRDAQ +DE+ YFFRV
Sbjct: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
Query: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
ERGS VR++F+++ FFLKVTALT+KPDVYIPETLEPGQPVTVICVFNWAF++CP PSFSW
Sbjct: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
Query: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
TGAALS + T+P+TSHFSVLSFTP PQDH+TDLTCHVDFSRKGVSAQRTVRLRVAYAP+D
Sbjct: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
Query: 254 LIISISHDNTSALE--LQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
L+ISIS DNT ALE QGNV YLE QKGQFLRLLCAADSQPPATLSWVLQ+RVLSSSHP
Sbjct: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
Query: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
WGPR LGLEL GV+AGDSGRYTCRAENRLGSQQ+ALDLSVQYPPENLRVMVSQANRTVLE
Sbjct: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE 360
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHE 431
NLGNGTSLPVLEGQSL LVCVTHSSPPARLSWT+ GQ + PSQPSDPGVLELP +Q+EHE
Sbjct: 361 NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE 420
Query: 432 GEFTCHAQHPLGSQHVSLSLSVHW 455
GEFTCHA+HPLGSQHVSLSLSVH+
Sbjct: 421 GEFTCHARHPLGSQHVSLSLSVHY 444
Score = 122 bits (307), Expect = 7e-28
Identities = 116/397 (29%), Positives = 165/397 (41%), Gaps = 70/397 (17%)
Query: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
TC + +R G S QR + L V Y P++L + +S N + LE GN L V +GQ L L+
Sbjct: 322 TCRAE-NRLG-SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
Query: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
C S PPA LSW + +VLS S P P L EL V+ G +TC A + LGSQ +
Sbjct: 380 CVTHSSPPARLSWTQRGQVLSPSQPSDPGVL--ELPRVQVEHEGEFTCHARHPLGSQHVS 437
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L LSV Y P+ L S E + L C + +SP L W
Sbjct: 438 LSLSVHYSPKLLGPSCSW------------------EAEGLHCSCSSQASPAPSLRWWLG 479
Query: 407 GQTVGPSQ--------PSDPGVLELPPIQMEHEG-----EFTCHAQHPLGSQHVSLSLSV 453
+ + + PS G + + H G C A + G+Q S+
Sbjct: 480 EELLEGNSSQDSFEVTPSSAGPWANSSLSL-HGGLSSGLRLRCEAWNVHGAQSGSILQLP 538
Query: 454 HWKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEA----RKRAAAEQ------ 503
K GA LG G+ ALL C L++ ++ R+ R R +
Sbjct: 539 DKKGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYI 598
Query: 504 DVPSTLGPISQGHQHECSAGSSQDHPPPGA-----------------------ATYTPGK 540
+V T GP++Q + + S + PPGA +T P
Sbjct: 599 NVVPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPES 658
Query: 541 GEEQ-ELHYASLSFQGLRLWEPADQEAPSTTEYSEIK 576
E Q ELHYA+L+F G+R A + +Y+E+K
Sbjct: 659 QESQEELHYATLNFPGVRPRPEARMPKGTQADYAEVK 695
Score = 80.9 bits (198), Expect = 3e-15
Identities = 62/194 (31%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 277 VQKGQFLRLLC----AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRY 332
++ GQ + ++C A + PP + SW + P L +
Sbjct: 154 LEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDL 213
Query: 333 TCRAE-NRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE---GQSL 387
TC + +R G S Q+ + L V Y P +L + +S+ N LE G ++P LE GQ L
Sbjct: 214 TCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQG-NVPYLEAQKGQFL 272
Query: 388 RLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVL--ELPPIQMEHEGEFTCHAQHPLGSQ 445
RL+C S PPA LSW + + S P P L ELP ++ G +TC A++ LGSQ
Sbjct: 273 RLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQ 332
Query: 446 HVSLSLSVHWKLEH 459
+L LSV + E+
Sbjct: 333 QRALDLSVQYPPEN 346
>gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens]
Length = 551
Score = 340 bits (873), Expect = 2e-93
Identities = 234/577 (40%), Positives = 305/577 (52%), Gaps = 44/577 (7%)
Query: 15 LLPLLL-PVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
+LPLLL P+L GSL + P Y LQVQ+ V V EGLCV+V C+ SYP W S Y YW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
F+ P VATNN R V+ T+ RF+L GD K +CSL I DA+ ED YFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
ERG V++S+ N L+VTAL +KPD++ E LE G+P + C + + P +FSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
TG ALSP P T+ S L+ TP P+DH T+LTC + V+ +RTV+L V+YAP+
Sbjct: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQT 238
Query: 254 LIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG 313
+ I N ALE+ N YL V +GQ LRLLC A S PPA LSW L+++
Sbjct: 239 ITI---FRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPI-- 293
Query: 314 PRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENL 373
T LELR VR+ + G +TCRA++ LG Q L+LSV P+ L S
Sbjct: 294 SNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCS---------- 343
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSW----------TRWGQTVGPSQPSDPGVLEL 423
E + L C + P L W + G S + P
Sbjct: 344 --------WEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSS 395
Query: 424 PPIQ--MEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAGVAALLAFCS 481
+ + + + +C A + GSQ S+ L + + G G+ A GAGV ALL C
Sbjct: 396 LILHGGLSSDLKVSCKAWNIYGSQSGSV-LLLQGRSNLGTGVVPAALGGAGVMALLCICL 454
Query: 482 CLVVFR-VKICRKEARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDH-PPPGAATYTPG 539
CL+ F VK RK+A R D +G I+ G + + S D PPG A P
Sbjct: 455 CLIFFLIVKARRKQAAGRPEKMDDEDPIMGTITSGSRKKPWPDSPGDQASPPGDA---PP 511
Query: 540 KGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIK 576
E++ELHYASLSF ++ EP DQEAPSTTEYSEIK
Sbjct: 512 LEEQKELHYASLSFSEMKSREPKDQEAPSTTEYSEIK 548
>gi|16506828 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform a precursor [Homo sapiens]
Length = 595
Score = 288 bits (736), Expect = 1e-77
Identities = 219/603 (36%), Positives = 304/603 (50%), Gaps = 48/603 (7%)
Query: 13 MLLLPLLLPVLGAGSLN--KDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAY 70
MLLL LLLP L G + + Y L +Q+ V V EGLCV V C+ SYP++GW S +
Sbjct: 1 MLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVH 60
Query: 71 GYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYF 130
GYWF+ PVATNN +R V+ TRDRF L GDP C+L IRD + D Y
Sbjct: 61 GYWFRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYV 120
Query: 131 FRVERGSRVRHSFLSNAFFLKVTA---LTKKPDVYIPE--TLEPGQPVTVICV-----FN 180
F VERG+ ++ ++ + + VTA L + + +PE T++ G V+V C +N
Sbjct: 121 FCVERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYN 179
Query: 181 WAFKKCPAPSFSWTGAAL---------SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVD 231
W S+ GA + +P +H L PQ ++ L+ +
Sbjct: 180 WTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFL-LLGDPQTNNCSLS--IR 236
Query: 232 FSRKGVSAQRTVRLRVAYAPKDLIIS-ISHDNTSALELQGNVIYLEVQKGQFLRLLC--- 287
+RKG S + ++ + I +S T+ + I ++ G L C
Sbjct: 237 DARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVP 296
Query: 288 -AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQ 344
A + P T++W+ +SS P R+ L L TC+ +
Sbjct: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354
Query: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404
+A+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT
Sbjct: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414
Query: 405 RWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH----WKLEHG 460
T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+ K+
Sbjct: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPI 474
Query: 461 GGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRA-----AAEQDVPSTLGPISQG 515
G+ LGA GAG AL+ C++ V+ CRK++ + A +D + G SQG
Sbjct: 475 SGVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQG 534
Query: 516 HQHECSAGSS-QDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSE 574
E A S H PP AT +P EE E+ YASLSF R P +QEA EYSE
Sbjct: 535 PLIESPADDSPPHHAPPALATPSP---EEGEIQYASLSFHKARPQYPQEQEAIG-YEYSE 590
Query: 575 IKI 577
I I
Sbjct: 591 INI 593
>gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens]
Length = 396
Score = 273 bits (699), Expect = 3e-73
Identities = 156/341 (45%), Positives = 206/341 (60%), Gaps = 7/341 (2%)
Query: 15 LLPLLL-PVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
+LPLLL P+L GSL + P Y LQVQ+ V V EGLCV+V C+ SYP W S Y YW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
F+ P VATNN R V+ T+ RF+L GD K +CSL I DA+ ED YFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
ERG V++S+ N L+VTAL +KPD++ E LE G+P + C + + P +FSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
TG ALSP P T+ S L+ TP P+DH T+LTC V V+ +RTV+L V+YAP++
Sbjct: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
Query: 254 LIISISHDN--TSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
L ISI N +AL + N + + +Q+GQ L L C DS PPA+LSW + + L+ S
Sbjct: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
Query: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
T LEL + A + G +TCR ++ LGSQ + LSVQ
Sbjct: 299 SMSGT--LELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
Score = 123 bits (309), Expect = 4e-28
Identities = 81/200 (40%), Positives = 109/200 (54%), Gaps = 13/200 (6%)
Query: 264 SALELQGNVIYLE-VQKGQFLRLLCA----ADSQPPATLSWVLQDRVLSSSHPWGPRTLG 318
+AL + ++ +LE ++ G+ RL C+ ++ PP T SW LS P R+
Sbjct: 140 TALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSE 197
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQ---QQALDLSVQYPPENLRVMVSQANRT--VLENL 373
L L TC+ + R G+Q ++ + L+V Y P+NL + + N T L L
Sbjct: 198 LTLTPRPEDHGTNLTCQVK-RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRIL 256
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGE 433
NG S+P+ EGQSL L C S+PPA LSW R G+ + PSQ S G LELP I GE
Sbjct: 257 SNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGE 316
Query: 434 FTCHAQHPLGSQHVSLSLSV 453
FTC QHPLGSQH+S LSV
Sbjct: 317 FTCRVQHPLGSQHLSFILSV 336
>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
Length = 499
Score = 271 bits (694), Expect = 1e-72
Identities = 165/379 (43%), Positives = 208/379 (54%), Gaps = 33/379 (8%)
Query: 13 MLLLPLLLPVL-GAGSLNKDPSYS----LQVQRQVPVPEGLCVIVSCNLSYPRDGWDEST 67
MLLL LLLP+L G + D Y LQVQ V V EGLCV V C+ SYP+DGW +S
Sbjct: 1 MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSD 60
Query: 68 AAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEA 127
+GYWF+ P APVATNN REV+ T+ RFQL GD CSL IRDA++ D+
Sbjct: 61 PVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKG 120
Query: 128 WYFFRVERGS-----RVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWA 182
YFFR+ERGS + + ++ + + VTALT +PD+ I TLE G + C WA
Sbjct: 121 SYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWA 180
Query: 183 FKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRT 242
K+ P SW GA++S P+T+ SVL+ TP PQDH T LTC V GV+ T
Sbjct: 181 CKQGTPPMISWIGASVS--SPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTST 238
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQ 302
VRL V+Y P +L +++ + +A GN L V +GQ LRL+CA +S PPA LSW
Sbjct: 239 VRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRG 298
Query: 303 DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMV 362
L S P LEL V D G +TCRA+N GSQ +L LS
Sbjct: 299 SLTLCPSRSSNPGL--LELPRVHVRDEGEFTCRAQNAQGSQHISLSLS------------ 344
Query: 363 SQANRTVLENLGNGTSLPV 381
L+N G GTS PV
Sbjct: 345 -------LQNEGTGTSRPV 356
Score = 191 bits (484), Expect = 2e-48
Identities = 137/361 (37%), Positives = 188/361 (52%), Gaps = 34/361 (9%)
Query: 238 SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYL-EVQKGQFLRLLC----AADSQ 292
S + + + ++ Y K L + ++ AL + +++ L ++ G L C A
Sbjct: 130 SMKWSYKSQLNYKTKQLSVFVT-----ALTHRPDILILGTLESGHSRNLTCSVPWACKQG 184
Query: 293 PPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQQALDLS 350
P +SW+ +SS P R+ L L TC+ + + L
Sbjct: 185 TPPMISWI--GASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLD 242
Query: 351 VQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV 410
V YPP NL + V Q + T LGNG+SL VLEGQSLRLVC +S+PPARLSWTR T+
Sbjct: 243 VSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTL 302
Query: 411 GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGG-------L 463
PS+ S+PG+LELP + + EGEFTC AQ+ GSQH+SLSLS+ G G +
Sbjct: 303 CPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQ---NEGTGTSRPVSQV 359
Query: 464 GLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAA-----AEQDVPSTLGPISQGHQH 518
L A GAG AL C++ V+ CRK++ + AA +D + G SQG
Sbjct: 360 TLAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLT 419
Query: 519 EC-SAGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 577
E G+ PPP A P GEE ELHYA+LSF ++ +P QEA + +EYSEIKI
Sbjct: 420 ESWKDGNPLKKPPPAVA---PSSGEEGELHYATLSFHKVKPQDPQGQEA-TDSEYSEIKI 475
Query: 578 H 578
H
Sbjct: 476 H 476
>gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo
sapiens]
Length = 467
Score = 264 bits (675), Expect = 2e-70
Identities = 147/344 (42%), Positives = 199/344 (57%), Gaps = 11/344 (3%)
Query: 14 LLLPLLLPVLGA-----GSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTA 68
+LL LLLP+L G + YSL +Q V V EG+CV V C+ SYP D +S
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128
+GYWF+ APVATNN + V+ TRDRF L GDP +C+L IRDA+ D
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA 188
YFFR+E+G+ ++ ++ + + VTALT +P++ IP TLE G + C WA ++
Sbjct: 121 YFFRMEKGN-IKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTP 179
Query: 189 PSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVA 248
P SW G ++SP PST+ SVL+ P PQ H T LTC V GV+ RT++L V+
Sbjct: 180 PMISWMGTSVSP--LHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVS 237
Query: 249 YAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSS 308
Y P++L +++ +A GN L V +GQ LRL+CA DS PPA LSW + L
Sbjct: 238 YPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYP 297
Query: 309 SHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q
Sbjct: 298 SQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 338
Score = 177 bits (449), Expect = 2e-44
Identities = 131/332 (39%), Positives = 177/332 (53%), Gaps = 24/332 (7%)
Query: 262 NTSALELQGNVIYL-EVQKGQFLRLLC----AADSQPPATLSWVLQDRVLSSSHPWGPRT 316
N +AL + N++ ++ G F L C A + P +SW+ +S HP R+
Sbjct: 142 NVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWM--GTSVSPLHPSTTRS 199
Query: 317 LGLELRGVRAGDSGRYTCRAE--NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLG 374
L L TC+ + + + L+V YPP+NL V V Q T LG
Sbjct: 200 SVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALG 259
Query: 375 NGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEF 434
N +SL VLEGQSLRLVC S+PPARLSWT T+ PSQPS+P VLEL + + EGEF
Sbjct: 260 NSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEF 318
Query: 435 TCHAQHPLGSQHVSLSLSVH----WKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKI 490
TC AQ+ LGSQHVSL+LS+ K+ G+ LGA GAG AL+ C++ V+
Sbjct: 319 TCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRS 378
Query: 491 CRKEARKRAA-----AEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQE 545
CRK++ + AA +D + G SQG+ E A + H G A ++ GEE+E
Sbjct: 379 CRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRH--HGLAAHS--SGEERE 434
Query: 546 LHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 577
+ YA LSF + + QEA + EYSEIKI
Sbjct: 435 IQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKI 465
>gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens]
Length = 463
Score = 250 bits (638), Expect = 3e-66
Identities = 147/343 (42%), Positives = 197/343 (57%), Gaps = 10/343 (2%)
Query: 15 LLPLLLPVL-GAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGW-DESTAAYGY 72
+L LLLP+L G S L +Q V V EGLCV V C+ SYP GW +GY
Sbjct: 1 MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGY 60
Query: 73 WFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFR 132
WF+ + APVATNN +R V TRDRF L GDP +C+L IRDA+R D YFFR
Sbjct: 61 WFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFR 120
Query: 133 VERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFS 192
+E+GS ++ ++ + + VTALT +P++ IP TLE G P + C WA ++ P S
Sbjct: 121 MEKGS-IKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMIS 179
Query: 193 WTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPK 252
W G ++SP PST+ SVL+ P PQDH T LTC V F V+ +TV L V+Y P+
Sbjct: 180 WIGTSVSP--LDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQ 237
Query: 253 DLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC---AADSQPPATLSWVLQDRVLSSS 309
+L +++ + + + GN L + +GQ LRL+C A DS PPA LS + L S
Sbjct: 238 NLTMTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPS 297
Query: 310 HPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
P P LEL V D+ +TCRA+N LGSQQ L++S+Q
Sbjct: 298 QPSNPGV--LELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQ 338
Score = 179 bits (455), Expect = 5e-45
Identities = 131/333 (39%), Positives = 179/333 (53%), Gaps = 24/333 (7%)
Query: 262 NTSALELQGNVIYL-EVQKGQFLRLLC----AADSQPPATLSWVLQDRVLSSSHPWGPRT 316
N +AL + N++ ++ G L C A + P +SW+ +S P R+
Sbjct: 138 NVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWI--GTSVSPLDPSTTRS 195
Query: 317 LGLELRGVRAGDSGRYTCRAENRLGS--QQQALDLSVQYPPENLRVMVSQANRTVLENLG 374
L L TC+ S + + L+V YPP+NL + V Q + TV LG
Sbjct: 196 SVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLG 255
Query: 375 NGTSLPVLEGQSLRLVCVTH---SSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHE 431
NG+SL + EGQSLRLVC S+PPARLS + G T+ PSQPS+PGVLELP + +
Sbjct: 256 NGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDA 315
Query: 432 GEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKIC 491
EFTC AQ+PLGSQ V L++S+ K G+ G GAG AL+ C++ V+ C
Sbjct: 316 AEFTCRAQNPLGSQQVYLNVSLQSKAT--SGVTQGVVGGAGATALVFLSFCVIFVVVRSC 373
Query: 492 RKEARKRAAAE-----QDVPSTLGPISQGHQHE-CSAGSSQDHPPPGAATYTPGKGEEQE 545
RK++ + AA +D + G SQG E + S D PPP +A + G+G E
Sbjct: 374 RKKSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARSSVGEG---E 430
Query: 546 LHYASLSFQGLRLWEPADQEAPSTTEYSEIKIH 578
L YASLSFQ ++ W+ QEA + TEYSEIKIH
Sbjct: 431 LQYASLSFQMVKPWDSRGQEA-TDTEYSEIKIH 462
>gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1
precursor [Homo sapiens]
Length = 453
Score = 248 bits (634), Expect = 9e-66
Identities = 145/342 (42%), Positives = 199/342 (58%), Gaps = 12/342 (3%)
Query: 15 LLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWF 74
+LPLLLP+L AG+L ++ + L+ + V EGLCV+V C L S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPA---SYYGYGYWF 68
Query: 75 KGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVE 134
PVATN+ EV+ TR RF L DP + +CSL IRDA+R D A YFFR+
Sbjct: 69 LEGAD----VPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 135 RGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
+ +++ + S+ ++V ALT +P++ IP TLE G P + C W ++ P FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 195 GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL 254
AA P P T+ SVL+ TP PQDH T+LTC V F GV+ +RT++L V+YAP+ +
Sbjct: 184 SAA--PTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 255 IISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
ISI N++A ++ N L V +GQ LRLLC AD PPA LSW L+++
Sbjct: 242 AISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPI--S 299
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPE 356
T LEL V + + G +TCRA++ LGS Q +L L V + PE
Sbjct: 300 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 341
Score = 182 bits (462), Expect = 8e-46
Identities = 103/237 (43%), Positives = 136/237 (57%), Gaps = 9/237 (3%)
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
+ ++ + L+V Y P+ + + + Q N + L N +SLPVLEGQ+LRL+C +PPA L
Sbjct: 225 TMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHL 284
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGG 461
SW + + + S+ GVLELP + EG+FTC AQHPLGS +SLSL VHWK E
Sbjct: 285 SWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPEGRA 344
Query: 462 GLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECS 521
G LGA GA + L+ C C +FRVK RK+A + DV + S+GHQH+
Sbjct: 345 GGVLGAVWGASITTLVFLCVCF-IFRVKTRRKKAAQPVQNTDDVNPVMVSGSRGHQHQFQ 403
Query: 522 AGSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIH 578
G DHP A P +EQELHYA L F ++ EP + TEYSEIKIH
Sbjct: 404 TGIVSDHP----AEAGPISEDEQELHYAVLHFHKVQPQEP----KVTDTEYSEIKIH 452
>gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3
precursor [Homo sapiens]
Length = 353
Score = 244 bits (623), Expect = 2e-64
Identities = 143/339 (42%), Positives = 197/339 (58%), Gaps = 12/339 (3%)
Query: 15 LLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWF 74
+LPLLLP+L AG+L ++ + L+ + V EGLCV+V C L S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPA---SYYGYGYWF 68
Query: 75 KGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVE 134
PVATN+ EV+ TR RF L DP + +CSL IRDA+R D A YFFR+
Sbjct: 69 LEGAD----VPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 135 RGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
+ +++ + S+ ++V ALT +P++ IP TLE G P + C W ++ P FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 195 GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL 254
AA P P T+ SVL+ TP PQDH T+LTC V F GV+ +RT++L V+YAP+ +
Sbjct: 184 SAA--PTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 255 IISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
ISI N++A ++ N L V +GQ LRLLC AD PPA LSW L+++
Sbjct: 242 AISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPI--S 299
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQY 353
T LEL V + + G +TCRA++ LGS Q +L L V +
Sbjct: 300 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHW 338
Score = 110 bits (276), Expect = 3e-24
Identities = 52/114 (45%), Positives = 73/114 (64%)
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
+ ++ + L+V Y P+ + + + Q N + L N +SLPVLEGQ+LRL+C +PPA L
Sbjct: 225 TMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHL 284
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHW 455
SW + + + S+ GVLELP + EG+FTC AQHPLGS +SLSL VHW
Sbjct: 285 SWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHW 338
>gi|16506826 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform b precursor [Homo sapiens]
Length = 477
Score = 239 bits (609), Expect = 7e-63
Identities = 137/320 (42%), Positives = 180/320 (56%), Gaps = 7/320 (2%)
Query: 34 YSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSR 93
Y L+V V V EGLCV V C++ YP W S+ YG WFK PVATN S
Sbjct: 33 YRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGADIPWDIPVATNTPSG 92
Query: 94 EVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVT 153
+V+ T RF L GDP +CSL IRDA++ D Y+F+VERGSR + +++ + + VT
Sbjct: 93 KVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR-KWNYIYDKLSVHVT 151
Query: 154 ALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVL 213
ALT P IP TLE G P + C WA ++ P+ +W GA++S P+ + S+L
Sbjct: 152 ALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVS--SLDPTITRSSML 209
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
S P PQDH T LTC V GV+ R VRL ++Y P++L +++ + +A N
Sbjct: 210 SLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGS 269
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332
L V +GQ L L+CA DS PPA LSW LS S LG LEL V D G +
Sbjct: 270 ALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQ---SSNLGVLELPRVHVKDEGEF 326
Query: 333 TCRAENRLGSQQQALDLSVQ 352
TCRA+N LGSQ +L LS+Q
Sbjct: 327 TCRAQNPLGSQHISLSLSLQ 346
Score = 184 bits (468), Expect = 2e-46
Identities = 125/302 (41%), Positives = 165/302 (54%), Gaps = 18/302 (5%)
Query: 288 AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE--NRLGSQQQ 345
A + P T++W+ +SS P R+ L L TC+ + +
Sbjct: 180 ACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTR 237
Query: 346 ALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTR 405
A+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT
Sbjct: 238 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTW 297
Query: 406 WGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH----WKLEHGG 461
T+ PSQ S+ GVLELP + ++ EGEFTC AQ+PLGSQH+SLSLS+ K+
Sbjct: 298 GSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPIS 357
Query: 462 GLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRA-----AAEQDVPSTLGPISQGH 516
G+ LGA GAG AL+ C++ V+ CRK++ + A +D + G SQG
Sbjct: 358 GVTLGAFGGAGATALVFLYFCIIFVVVRSCRKKSARPAVGVGDTGMEDANAVRGSASQGP 417
Query: 517 QHECSAGSS-QDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEI 575
E A S H PP AT +P EE E+ YASLSF R P +QEA EYSEI
Sbjct: 418 LIESPADDSPPHHAPPALATPSP---EEGEIQYASLSFHKARPQYPQEQEAIG-YEYSEI 473
Query: 576 KI 577
I
Sbjct: 474 NI 475
>gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2
precursor [Homo sapiens]
Length = 437
Score = 225 bits (574), Expect = 8e-59
Identities = 138/342 (40%), Positives = 188/342 (54%), Gaps = 28/342 (8%)
Query: 15 LLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWF 74
+LPLLLP+L AG+L ++ + L+ + V EGLCV+V C L S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPA---SYYGYGYWF 68
Query: 75 KGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVE 134
PVATN+ EV+ TR RF L DP + +CSL IRDA+R D A YFFR+
Sbjct: 69 LEGAD----VPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 135 RGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
+ +++ + S+ ++V ALT +P++ IP TLE G P + C W ++ P FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 195 GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL 254
AA P P T+ SVL+ TP PQDH T+LTC V F GV+ +RT++L
Sbjct: 184 SAA--PTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQL--------- 232
Query: 255 IISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
N S+ ++ N L V +GQ LRLLC AD PPA LSW L+++
Sbjct: 233 -------NVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPI--S 283
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPE 356
T LEL V + + G +TCRA++ LGS Q +L L V + PE
Sbjct: 284 NTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 325
Score = 168 bits (425), Expect = 1e-41
Identities = 99/215 (46%), Positives = 124/215 (57%), Gaps = 9/215 (4%)
Query: 364 QANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLEL 423
Q N + + L N +SLPVLEGQ+LRL+C +PPA LSW + + + S+ GVLEL
Sbjct: 231 QLNVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLEL 290
Query: 424 PPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAALGAGVAALLAFCSCL 483
P + EG+FTC AQHPLGS +SLSL VHWK E G LGA GA + L+ C C
Sbjct: 291 PQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPEGRAGGVLGAVWGASITTLVFLCVCF 350
Query: 484 VVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEE 543
+FRVK RK+A + DV + S+GHQH+ G DHP A P +E
Sbjct: 351 -IFRVKTRRKKAAQPVQNTDDVNPVMVSGSRGHQHQFQTGIVSDHP----AEAGPISEDE 405
Query: 544 QELHYASLSFQGLRLWEPADQEAPSTTEYSEIKIH 578
QELHYA L F ++ EP + TEYSEIKIH
Sbjct: 406 QELHYAVLHFHKVQPQEP----KVTDTEYSEIKIH 436
>gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens]
Length = 364
Score = 214 bits (546), Expect = 1e-55
Identities = 114/260 (43%), Positives = 158/260 (60%), Gaps = 4/260 (1%)
Query: 16 LPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYWFK 75
L LLLP+L AG+L DP++ LQVQ V V EGLCV+V C +P +D+++ +GYWF+
Sbjct: 3 LLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYWFR 62
Query: 76 GRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVER 135
+PVATN +EV+ T+ RF+L GDP + +CSL I DA+R D YFFR+ER
Sbjct: 63 EGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRMER 122
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTG 195
GS ++S+ S + VT LT +P + IP TLEPG + C +WA ++ P FSW
Sbjct: 123 GS-TKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLS 181
Query: 196 AALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLI 255
AA P P T+H SVL TP PQDH T+LTC V F+ GV+ +RT++L V Y P++
Sbjct: 182 AA--PTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPT 239
Query: 256 ISI-SHDNTSALELQGNVIY 274
I D + E + V++
Sbjct: 240 TGIFPGDGSGKQETRAGVVH 259
Score = 72.8 bits (177), Expect = 9e-13
Identities = 80/281 (28%), Positives = 113/281 (40%), Gaps = 44/281 (15%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L + R D+G Y R E GS + + Y L V V+ + L GT
Sbjct: 103 LSIVDARRRDNGSYFFRMER--GSTKYS------YKSPQLSVHVTDLTHRP-KILIPGTL 153
Query: 379 LPVLEGQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEF 434
P G S L C P SW T + + VL + P +H
Sbjct: 154 EP---GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNL 210
Query: 435 TCHAQHPLG--SQHVSLSLSVHW----------------KLEHGGGLGLGAALGAGVAAL 476
TC + + ++ L+V + K E G+ GA GAGV AL
Sbjct: 211 TCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTAL 270
Query: 477 LAFCSCLVVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSA-GSSQDHPPPGAAT 535
LA C CL+ F VK R++A + A D T G S HQ + G ++ GAA
Sbjct: 271 LALCLCLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAA- 329
Query: 536 YTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIK 576
P ++ELHYASL+F G+ + ++TEYSE++
Sbjct: 330 --PTVEMDEELHYASLNFHGM------NPSKDTSTEYSEVR 362
>gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo
sapiens]
Length = 374
Score = 181 bits (458), Expect = 2e-45
Identities = 125/295 (42%), Positives = 165/295 (55%), Gaps = 21/295 (7%)
Query: 298 SWVLQDRVLSSSHPWG-PRTLG--LELRGVRAGDSGRYTCRAEN---RLGSQQQALDLSV 351
+W +Q+ H G P+T L +R R D+GRY R E + + L ++V
Sbjct: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNV 143
Query: 352 QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVG 411
PP+NL V V Q T LGN +SL VLEGQSLRLVC S+PPARLSWT T+
Sbjct: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203
Query: 412 PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH----WKLEHGGGLGLGA 467
PSQPS+P VLEL + + EGEFTC AQ+ LGSQHVSL+LS+ K+ G+ LGA
Sbjct: 204 PSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGA 262
Query: 468 ALGAGVAALLAFCSCLVVFRVKICRKEARKRAA-----AEQDVPSTLGPISQGHQHECSA 522
GAG AL+ C++ V+ CRK++ + AA +D + G SQG+ E A
Sbjct: 263 VGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWA 322
Query: 523 GSSQDHPPPGAATYTPGKGEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIKI 577
+ H G A ++ GEE+E+ YA LSF + + QEA + EYSEIKI
Sbjct: 323 DDNPRH--HGLAAHS--SGEEREIQYAPLSFHKGEPQDLSGQEA-TNNEYSEIKI 372
Score = 112 bits (281), Expect = 7e-25
Identities = 73/213 (34%), Positives = 108/213 (50%), Gaps = 25/213 (11%)
Query: 14 LLLPLLLPVLGA-----GSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTA 68
+LL LLLP+L G + YSL +Q V V EG+CV V C+ SYP D +S
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128
+GYWF+ APVATNN + V+ TRDRF L GDP +C+L IRDA+ D
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE---------------TLEPGQPV 173
YFFR+E+G+ ++ ++ + + VT + V + + ++ GQ +
Sbjct: 121 YFFRMEKGN-IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179
Query: 174 TVICVFNWAFKKCPAPSFSWTGAALSPRRTRPS 206
++C A P SWT +L+ ++PS
Sbjct: 180 RLVC----AVDSNPPARLSWTWRSLTLYPSQPS 208
Score = 83.6 bits (205), Expect = 5e-16
Identities = 46/108 (42%), Positives = 62/108 (57%), Gaps = 3/108 (2%)
Query: 245 LRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDR 304
+ V P++L +++ +A GN L V +GQ LRL+CA DS PPA LSW +
Sbjct: 141 VNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSL 200
Query: 305 VLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
L S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q
Sbjct: 201 TLYPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 139 bits (349), Expect = 1e-32
Identities = 116/422 (27%), Positives = 182/422 (43%), Gaps = 56/422 (13%)
Query: 46 EGLCVIVSCNLSYPRDGWDESTAA--YGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRF 103
EG CV + C +P DE A +G W+ PK PV ++++ V S + R
Sbjct: 34 EGTCVSIPCRFDFP----DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRS 89
Query: 104 QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI 163
+L GD G +C+L++ + E Y+FR + G +++F ++ V + P++ +
Sbjct: 90 RLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHS----VLDIVNTPNIVV 145
Query: 164 PETLEPGQPVTVICVFNWAFKKCP--APSFSWTG-------AALSPRRTRPST-SHFSVL 213
P + G V V C+ CP P SW G A L R T S+L
Sbjct: 146 PPEVVAGTEVEVSCMVP---DNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLL 202
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
F P+ + + L C F + + + V Y P +I + + A+E
Sbjct: 203 HFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPP---VIVEMNSSVEAIE------ 253
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYT 333
G + LLC ADS PP L+W+ VL + +L LEL V + G Y
Sbjct: 254 ------GSHVSLLCGADSNPPPLLTWMRDGTVLREA---VAESLLLELEEVTPAEDGVYA 304
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C AEN G + + LSV Y P V NGT + V EG+++ ++C T
Sbjct: 305 CLAENAYGQDNRTVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCST 349
Query: 394 HSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
S+P L+ + Q + LELP + E +GE+ C A++ G + + +LSV
Sbjct: 350 QSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSV 409
Query: 454 HW 455
+
Sbjct: 410 EF 411
Score = 47.8 bits (112), Expect = 3e-05
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 17/115 (14%)
Query: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
RTV L V YAP ++ G ++ +E G+ + +LC+ S P L+
Sbjct: 316 RTVGLSVMYAPWKPTVN------------GTMVAVE---GETVSILCSTQSNPDPILTIF 360
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPP 355
+ ++LS+ L LEL V D G Y C AEN+ G + A +LSV++ P
Sbjct: 361 KEKQILSTVIY--ESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAP 413
>gi|18104957 myelin associated glycoprotein isoform b precursor
[Homo sapiens]
Length = 582
Score = 139 bits (349), Expect = 1e-32
Identities = 116/422 (27%), Positives = 182/422 (43%), Gaps = 56/422 (13%)
Query: 46 EGLCVIVSCNLSYPRDGWDESTAA--YGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRF 103
EG CV + C +P DE A +G W+ PK PV ++++ V S + R
Sbjct: 34 EGTCVSIPCRFDFP----DELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRS 89
Query: 104 QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI 163
+L GD G +C+L++ + E Y+FR + G +++F ++ V + P++ +
Sbjct: 90 RLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHS----VLDIVNTPNIVV 145
Query: 164 PETLEPGQPVTVICVFNWAFKKCP--APSFSWTG-------AALSPRRTRPST-SHFSVL 213
P + G V V C+ CP P SW G A L R T S+L
Sbjct: 146 PPEVVAGTEVEVSCMVP---DNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLL 202
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
F P+ + + L C F + + + V Y P +I + + A+E
Sbjct: 203 HFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPP---VIVEMNSSVEAIE------ 253
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYT 333
G + LLC ADS PP L+W+ VL + +L LEL V + G Y
Sbjct: 254 ------GSHVSLLCGADSNPPPLLTWMRDGTVLREA---VAESLLLELEEVTPAEDGVYA 304
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C AEN G + + LSV Y P V NGT + V EG+++ ++C T
Sbjct: 305 CLAENAYGQDNRTVGLSVMYAPWKPTV--------------NGTMVAV-EGETVSILCST 349
Query: 394 HSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
S+P L+ + Q + LELP + E +GE+ C A++ G + + +LSV
Sbjct: 350 QSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSV 409
Query: 454 HW 455
+
Sbjct: 410 EF 411
Score = 47.8 bits (112), Expect = 3e-05
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 17/115 (14%)
Query: 241 RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV 300
RTV L V YAP ++ G ++ +E G+ + +LC+ S P L+
Sbjct: 316 RTVGLSVMYAPWKPTVN------------GTMVAVE---GETVSILCSTQSNPDPILTIF 360
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPP 355
+ ++LS+ L LEL V D G Y C AEN+ G + A +LSV++ P
Sbjct: 361 KEKQILSTVIY--ESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAP 413
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 99.4 bits (246), Expect = 9e-21
Identities = 114/450 (25%), Positives = 182/450 (40%), Gaps = 70/450 (15%)
Query: 11 PEMLLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGW--DESTA 68
P++LLL P A S+ + + V +G C+++ C S+P D D TA
Sbjct: 5 PKLLLLASFFPAGQA-------SWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITA 57
Query: 69 AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAW 128
+ Y + G+ V+ + + VE R R + G+P C+L+++D Q ED
Sbjct: 58 IWYYDYSGQRQV-----VSHSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGS 112
Query: 129 YFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICV---------- 178
Y FR E R S + + VT + P + P L G V C
Sbjct: 113 YNFRFEISEVNRWSDVKGT-LVTVTEEPRVPTIASPVELLEGTEVDFNCSTPYVCLQEQV 171
Query: 179 -FNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGV 237
W + PA S ++ P H L S QDH L C + +
Sbjct: 172 RLQWQGQD-PARSVTFNSQKFEP----TGVGHLETLHMAMSWQDHGRILRCQLSVANH-- 224
Query: 238 SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPA-- 295
AQ + L+V YAPK + I +S + L G+ + L C +S PA
Sbjct: 225 RAQSEIHLQVKYAPKGVKILLSPSGRNIL------------PGELVTLTCQVNSSYPAVS 272
Query: 296 TLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPP 355
++ W L+D V + +T L L D+G YTC+AEN +G S+ PP
Sbjct: 273 SIKW-LKDGVRLQT-----KTGVLHLPQAAWSDAGVYTCQAENGVG--------SLVSPP 318
Query: 356 ENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP 415
+L + +++ + + P+LE Q++ LVC T + P+ L ++ W + +
Sbjct: 319 ISLHIFMAEVQVS--------PAGPILENQTVTLVCNTPNEAPSDLRYS-WYKNHVLLED 369
Query: 416 SDPGVLELPPIQMEHEGEFTCHAQHPLGSQ 445
+ L L G + C Q+ GS+
Sbjct: 370 AHSHTLRLHLATRADTGFYFCEVQNVHGSE 399
Score = 67.4 bits (163), Expect = 4e-11
Identities = 61/224 (27%), Positives = 93/224 (41%), Gaps = 37/224 (16%)
Query: 224 TDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFL 283
T C V + R + L V YAP++L ++ LE GQ
Sbjct: 1145 TSYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTY---------------LLESHGGQLA 1189
Query: 284 RLLCAADSQPPATLSWVLQDRVLSSSHPWG-PRTLGLELRGVRAGDSGRYTCRAENRLGS 342
+LC DS+PPA L+ R+L+SS P TL LELRG + D G Y+C A + LG
Sbjct: 1190 LVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQ 1249
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS-PPARL 401
+L+L + E +RV+++ V EG + + C ++ P
Sbjct: 1250 ANTSLELRL----EGVRVILA-------------PEAAVPEGAPITVTCADPAAHAPTLY 1292
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQ 445
+W G+ + Q L H G ++C AQ G++
Sbjct: 1293 TWYHNGRWL---QEGPAASLSFLVATRAHAGAYSCQAQDAQGTR 1333
Score = 65.1 bits (157), Expect = 2e-10
Identities = 100/399 (25%), Positives = 148/399 (37%), Gaps = 92/399 (23%)
Query: 95 VEMSTRDRFQLTGDPGKGSCS-------------------LVIRDAQREDEAWYFFRVER 135
+++ +DR T P G CS + I + E+E Y E
Sbjct: 634 LQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEEEGLYL--CEA 691
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW-- 193
+ + ++ S F + T L P TL+ G + C + PA +FSW
Sbjct: 692 SNALGNASTSATFNGQATVLAIAPS----HTLQEGTEANLTCNVSREAAGSPA-NFSWFR 746
Query: 194 TGA--ALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAP 251
G A P T ++ P + C + + G V L V Y P
Sbjct: 747 NGVLWAQGPLET---------VTLLPVARTDAALYACRI-LTEAGAQLSTPVLLSVLYPP 796
Query: 252 KDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
SAL L++ +G +C DS+P A L+ + +L++S
Sbjct: 797 -------DRPKLSAL--------LDMGQGHMALFICTVDSRPLALLALFHGEHLLATS-- 839
Query: 312 WGPR--------------TLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPEN 357
GP+ +L LE+R + GDSG Y C A N LGS +L V+
Sbjct: 840 LGPQVPSHGRFQAKAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVR----G 895
Query: 358 LRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSD 417
V VS S + EGQ++ L C H+ P S+ RW + P Q S
Sbjct: 896 AWVQVS-------------PSPELQEGQAVVLSCQVHTGVPEGTSY-RWYRDGQPLQEST 941
Query: 418 PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLS--LSVH 454
L I + G + C AQ P GS SL+ +S+H
Sbjct: 942 SATLRFAAITLTQAGAYHCQAQAP-GSATTSLAAPISLH 979
Score = 64.7 bits (156), Expect = 2e-10
Identities = 93/398 (23%), Positives = 148/398 (37%), Gaps = 78/398 (19%)
Query: 96 EMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTAL 155
++ + RFQ + S L +R+ D Y R E + + S S F ++ +
Sbjct: 843 QVPSHGRFQAKAEAN--SLKLEVRELGLGDSGSY--RCEATNVLGSSNTSLFFQVRGAWV 898
Query: 156 TKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSF 215
P PE L+ GQ V + C + + S+ W + + +T F+ ++
Sbjct: 899 QVSPS---PE-LQEGQAVVLSCQVHTGVPE--GTSYRWYRDGQPLQESTSATLRFAAITL 952
Query: 216 TPSPQDHDTDLTCHVDFSRKGV-SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIY 274
T + H C S + L V+YAP+ + ++
Sbjct: 953 TQAGAYH-----CQAQAPGSATTSLAAPISLHVSYAPRHVTLTT---------------L 992
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWG----------PRTLGL 319
++ G+ LLC DS PPA L + DR+++S+ P G P TL L
Sbjct: 993 MDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRL 1052
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
E+ G D G Y C A N LG + D Q N+
Sbjct: 1053 EIHGAMLEDEGVYICEASNTLGQASASADFDAQ-----------------AVNVQVWPGA 1095
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQ 439
V EGQ + L C+ ++ PA+L++T W Q Q D + LP + + + C
Sbjct: 1096 TVREGQLVNLTCLVWTTHPAQLTYT-WYQ--DGQQRLDAHSIPLPNVTVRDATSYRCGVG 1152
Query: 440 HP-----------LGSQHVSLSLSVHWKLE-HGGGLGL 465
P L + +L + + LE HGG L L
Sbjct: 1153 PPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLAL 1190
Score = 56.6 bits (135), Expect = 6e-08
Identities = 54/179 (30%), Positives = 74/179 (41%), Gaps = 33/179 (18%)
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSS-----------SHPWGPRTLGLELR 322
+LE Q G L C+ S+P ATL +L+S S GP +L LE+R
Sbjct: 420 FLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIR 479
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ DSG Y C A N LG+ LD + R+++S A V+
Sbjct: 480 DLEETDSGEYKCSATNSLGNATSTLD----FHANAARLLISPA-------------AEVV 522
Query: 383 EGQSLRLVCVTHSS--PPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQ 439
EGQ++ L C + S P AR SW G + S L LP G + C A+
Sbjct: 523 EGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSS---LLLPAASSTDAGSYHCRAR 578
Score = 54.7 bits (130), Expect = 2e-07
Identities = 87/345 (25%), Positives = 128/345 (37%), Gaps = 67/345 (19%)
Query: 116 LVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTV 175
L +R Q DE F+ S + + S L+ + P+ +PE G P+TV
Sbjct: 1226 LELRGPQPRDEG--FYSCSARSPLGQANTSLELRLEGVRVILAPEAAVPE----GAPITV 1279
Query: 176 ICVFNWAFKKCPAPS-FSW--TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDF 232
C A AP+ ++W G L + P+ S LSF + + H +C
Sbjct: 1280 TC----ADPAAHAPTLYTWYHNGRWL---QEGPAAS----LSFLVATRAHAGAYSCQAQ- 1327
Query: 233 SRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQ 292
+G + R L+V YAP+D ++S D+ + + C DS+
Sbjct: 1328 DAQGTRSSRPAALQVLYAPQDAVLSSFRDSRAR---------------SMAVIQCTVDSE 1372
Query: 293 PPATLSWVLQDRVLSSS---HPWGPRT---------LGLELRGVRAGDSGRYTCRAENRL 340
PPA L+ +VL++S H T L L+++ V AGD Y C A+N L
Sbjct: 1373 PPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDD-TYVCTAQNLL 1431
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP-PA 399
GS L V E RV+ L V EG +L L C P P
Sbjct: 1432 GSISTIGRLQV----EGARVVAE-------------PGLDVPEGAALNLSCRLLGGPGPV 1474
Query: 400 RLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
S W L + G + C A+ P G+
Sbjct: 1475 GNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGA 1519
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 29/182 (15%)
Query: 277 VQKGQFLRLLCAADSQPPA--TLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTC 334
V++GQ + L C + PA T +W + +H + L V D+ Y C
Sbjct: 1097 VREGQLVNLTCLVWTTHPAQLTYTWYQDGQQRLDAH-------SIPLPNVTVRDATSYRC 1149
Query: 335 RA--ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
R + + L V Y P NLR+ +LE+ G GQ ++C
Sbjct: 1150 GVGPPGRAPRLSRPITLDVLYAPRNLRLTY------LLESHG---------GQLALVLCT 1194
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD-PGVL--ELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
S PPA+L+ + G+ + S + P L EL Q EG ++C A+ PLG + SL
Sbjct: 1195 VDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSL 1254
Query: 450 SL 451
L
Sbjct: 1255 EL 1256
Score = 50.1 bits (118), Expect = 6e-06
Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 27/119 (22%)
Query: 236 GVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPA 295
G +A V LRV Y PK + ++++E + G L C DS+P A
Sbjct: 1518 GAAASAPVMLRVLYPPKTPTM---------------MVFVEPEGGLRGILDCRVDSEPLA 1562
Query: 296 TLSWVLQDRVLSSSHPWG------------PRTLGLELRGVRAGDSGRYTCRAENRLGS 342
+L+ L R+++SS P G P L +++ +R D G Y C A N LGS
Sbjct: 1563 SLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLGS 1621
Score = 48.9 bits (115), Expect = 1e-05
Identities = 89/372 (23%), Positives = 125/372 (33%), Gaps = 82/372 (22%)
Query: 104 QLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI 163
+ +G G S L IRD + D Y + + + ++ + F L P +
Sbjct: 464 RFSGTSGPNSLRLEIRDLEETDSGEY--KCSATNSLGNATSTLDFHANAARLLISPAAEV 521
Query: 164 PETLEPGQPVTVICVFNWAFKKCPAPSFSW--TGAALSPRRTRPSTSHFSVLSFTPSPQD 221
E GQ VT+ C P FSW GA L H S P
Sbjct: 522 VE----GQAVTLSC--RSGLSPTPDARFSWYLNGALL----------HEGPGSSLLLPAA 565
Query: 222 HDTDLTCHVDFSRKGVSAQ---RTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQ 278
TD + +R G SA L V Y P+ + D +A
Sbjct: 566 SSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAA----------GAG 615
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG------------------PRTLGLE 320
G+ LLC DS PPA L + +DRV+++S P G P L +E
Sbjct: 616 AGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVE 675
Query: 321 LRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 380
+ + G Y C A N LG+ + + Q TVL + T
Sbjct: 676 IHNPLLEEEGLYLCEASNALGNASTSATFNGQ--------------ATVLAIAPSHT--- 718
Query: 381 VLEGQSLRLVCVTH---SSPPARLSWTR----WGQTVGPSQPSDPGVLELPPIQMEHEGE 433
+ EG L C + PA SW R W Q GP + + L P+
Sbjct: 719 LQEGTEANLTCNVSREAAGSPANFSWFRNGVLWAQ--GPLE-----TVTLLPVARTDAAL 771
Query: 434 FTCHAQHPLGSQ 445
+ C G+Q
Sbjct: 772 YACRILTEAGAQ 783
Score = 38.1 bits (87), Expect = 0.023
Identities = 50/198 (25%), Positives = 71/198 (35%), Gaps = 39/198 (19%)
Query: 275 LEVQKGQFLRLLCAADSQPP----ATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSG 330
L+V +G L L C P +T +W DR L + L V +G
Sbjct: 1453 LDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEP-----VPTLAFTHVARAQAG 1507
Query: 331 RYTCRAENRLGSQQQA-LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
Y C AE G+ A + L V YPP+ +MV L + L
Sbjct: 1508 MYHCLAELPTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGI---------------L 1552
Query: 390 VCVTHSSPPARLSWTRWGQTVGPSQP------------SDPGVL--ELPPIQMEHEGEFT 435
C S P A L+ + V SQP + P L ++ ++ +GE+
Sbjct: 1553 DCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYI 1612
Query: 436 CHAQHPLGSQHVSLSLSV 453
C A + LGS S V
Sbjct: 1613 CSASNVLGSASTSTYFGV 1630
Score = 32.3 bits (72), Expect = 1.3
Identities = 45/184 (24%), Positives = 71/184 (38%), Gaps = 36/184 (19%)
Query: 277 VQKGQFLRLLCAADSQPPATL--SWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTC 334
+ + Q + L+C ++ P+ L SW +L +H TL L L D+G Y C
Sbjct: 336 ILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHS---HTLRLHL--ATRADTGFYFC 390
Query: 335 RAENRLGSQQQA-LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
+N GS++ + + V +PP ++ LE + L C
Sbjct: 391 EVQNVHGSERSGPVSVVVNHPP------LTPVLTAFLETQAGLVGI---------LHCSV 435
Query: 394 HSSPPARLSWTRWG----QTVGPS--QPSDPGV-------LELPPIQMEHEGEFTCHAQH 440
S P A L + G T G S P G LE+ ++ GE+ C A +
Sbjct: 436 VSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATN 495
Query: 441 PLGS 444
LG+
Sbjct: 496 SLGN 499
>gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens]
Length = 237
Score = 96.3 bits (238), Expect = 7e-20
Identities = 50/121 (41%), Positives = 69/121 (57%), Gaps = 3/121 (2%)
Query: 155 LTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS 214
LT +P + IP TLEPG + C +WA ++ P FSW AA P P T+H SVL
Sbjct: 14 LTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAA--PTSLGPRTTHSSVLI 71
Query: 215 FTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISI-SHDNTSALELQGNVI 273
TP PQDH T+LTC V F+ GV+ +RT++L V Y P++ I D + E + V+
Sbjct: 72 ITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVV 131
Query: 274 Y 274
+
Sbjct: 132 H 132
Score = 72.4 bits (176), Expect = 1e-12
Identities = 63/216 (29%), Positives = 90/216 (41%), Gaps = 32/216 (14%)
Query: 384 GQSLRLVC----VTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQ 439
G S L C P SW T + + VL + P +H TC +
Sbjct: 29 GHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVK 88
Query: 440 HPLG--SQHVSLSLSVHW----------------KLEHGGGLGLGAALGAGVAALLAFCS 481
+ ++ L+V + K E G+ GA GAGV ALLA C
Sbjct: 89 FAGAGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCL 148
Query: 482 CLVVFRVKICRKEARKRAAAEQDVPSTLGPISQGHQHECSA-GSSQDHPPPGAATYTPGK 540
CL+ F VK R++A + A D T G S HQ + G ++ GAA P
Sbjct: 149 CLIFFIVKTHRRKAARTAVGRNDTHPTTGSASPKHQKKSKLHGPTETSSCSGAA---PTV 205
Query: 541 GEEQELHYASLSFQGLRLWEPADQEAPSTTEYSEIK 576
++ELHYASL+F G+ + ++TEYSE++
Sbjct: 206 EMDEELHYASLNFHGM------NPSKDTSTEYSEVR 235
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 89.0 bits (219), Expect = 1e-17
Identities = 95/411 (23%), Positives = 158/411 (38%), Gaps = 54/411 (13%)
Query: 46 EGLCVIVSCNLSYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQL 105
EG CV + C + + + TS G + + + +V S + R Q
Sbjct: 36 EGACVWIPCTYRALDGDLESFILFHNPEYNKNTSKFDGTRLYESTKDGKVP-SEQKRVQF 94
Query: 106 TGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE 165
GD K +C+L I D R+E + L V+ P + +P
Sbjct: 95 LGDKNK-NCTLSIHPVHLNDSGQLGLRMESKTEK----WMERIHLNVSERPFPPHIQLPP 149
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWT--------GAALSPRRTRPSTSHFSVLSFTP 217
++ Q VT+ C+ N++ P W A S T S S L F+P
Sbjct: 150 EIQESQEVTLTCLLNFSCYGYPI-QLQWLLEGVPMRQAAVTSTSLTIKSVFTRSELKFSP 208
Query: 218 SPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEV 277
H +TC + + + TV+L V + PK LE++ V
Sbjct: 209 QWSHHGKIVTCQLQDADGKFLSNDTVQLNVKHTPK-------------LEIKVTPSDAIV 255
Query: 278 QKGQFLRLLCAADSQPP--ATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCR 335
++G + + C S P T+SW+ L + T L LR V SG+Y C+
Sbjct: 256 REGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQN-----TFTLNLREVTKDQSGKYCCQ 310
Query: 336 AENRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
N +G + + + L VQY PE V + + P +EG + +C++
Sbjct: 311 VSNDVGPGRSEEVFLQVQYAPEPSTVQILHS--------------PAVEGSQVEFLCMSL 356
Query: 395 SSP-PARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
++P P +W G+ + Q + +P I H G ++C A++ LG+
Sbjct: 357 ANPLPTNYTWYHNGKEM---QGRTEEKVHIPKILPWHAGTYSCVAENILGT 404
Score = 71.6 bits (174), Expect = 2e-12
Identities = 78/332 (23%), Positives = 130/332 (39%), Gaps = 56/332 (16%)
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLS--WV 300
V L V YAP+D+ + + E+ G + L C S P + W
Sbjct: 497 VALNVQYAPRDVRVRKIKPLS------------EIHSGNSVSLQCDFSSSHPKEVQFFWE 544
Query: 301 LQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLG-SQQQALDLSVQYPPENLR 359
R+L L + D+G Y+C N +G + +A L V Y P LR
Sbjct: 545 KNGRLLGKESQ-------LNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLR 597
Query: 360 VMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP-ARLSWTRWGQTVGPSQPSDP 418
V +S ++ V+EG+S L C + ++PP + +W W S P
Sbjct: 598 VSMSPGDQ-------------VMEGKSATLTCESDANPPVSHYTWFDWNNQ---SLPYHS 641
Query: 419 GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLS-LSVHWKLEHGGGLGLGAALGAGVAALL 477
L L P++++H G + C + +G LS L+V++ E +G A+G G
Sbjct: 642 QKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTLTVYYSPE---TIGRRVAVGLG----- 693
Query: 478 AFCSCLVVFRVKICRKEAR---KRAAAEQDVPSTLGPISQGHQHECSAGSSQDHPPPGAA 534
SCL + + IC + + KR ++Q + S +++ + P
Sbjct: 694 ---SCLAILILAICGLKLQRRWKRTQSQQGLQENSSGQSFFVRNKKVRRAPLSEGPHSLG 750
Query: 535 TYTPGKGEEQELHYASLSFQGLRLWEPADQEA 566
Y P E + Y +L F + + D E+
Sbjct: 751 CYNPMM--EDGISYTTLRFPEMNIPRTGDAES 780
Score = 34.3 bits (77), Expect = 0.34
Identities = 43/187 (22%), Positives = 75/187 (40%), Gaps = 31/187 (16%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYT 333
+ +++G + L C +S P+ + + W +LG L+++ V D+
Sbjct: 430 MPIREGDTVTLSCNYNSSNPSVTRYEWKPH-----GAWEEPSLGVLKIQNV-GWDNTTIA 483
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N S + L+VQY P ++RV + + + E + G S+ L C
Sbjct: 484 CAACNSWCSWASPVALNVQYAPRDVRV---RKIKPLSE---------IHSGNSVSLQCDF 531
Query: 394 HSSPPARLS--WTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
SS P + W + G+ +G L I E G ++C + +G +
Sbjct: 532 SSSHPKEVQFFWEKNGRLLGKESQ-----LNFDSISPEDAGSYSCWVNNSIGQ-----TA 581
Query: 452 SVHWKLE 458
S W LE
Sbjct: 582 SKAWTLE 588
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 76.6 bits (187), Expect = 6e-14
Identities = 91/364 (25%), Positives = 146/364 (40%), Gaps = 66/364 (18%)
Query: 111 KGSCSLVIRDAQREDEAWYFFRVER--GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLE 168
+G L I++AQ D+ Y +V G VR L+ ++V + P ET+
Sbjct: 1892 RGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT----VQVPPTFENPKT---ETVS 1944
Query: 169 P--GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS-------FTPSP 219
G P+ + C + PAP+ +W L R S++ V+S P
Sbjct: 1945 QVAGSPLVLTCDVSGV----PAPTVTW----LKDRMPVESSAVHGVVSRGGRLQLSRLQP 1996
Query: 220 QDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQK 279
T TC + ++ A++ + V AP+ ++ ++ V +
Sbjct: 1997 AQAGT-YTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH-------------HVLE 2040
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL------GLELRGVRAGDSGRYT 333
GQ +RL C AD QPP ++W+ L GP L L+G+RA D+G YT
Sbjct: 2041 GQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAGAYT 2098
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G + ++V PP T+ + +L G+ + +VC
Sbjct: 2099 CVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMVCPV 2146
Query: 394 HSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
SPP +SW + G + SQ + L + +Q+ G FTC A P G +
Sbjct: 2147 RGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNF 2206
Query: 450 SLSV 453
+L V
Sbjct: 2207 TLQV 2210
Score = 73.9 bits (180), Expect = 4e-13
Identities = 81/315 (25%), Positives = 126/315 (40%), Gaps = 39/315 (12%)
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSP-QDHDTDLT 227
PG+ VT++C + P SW L ++ + H S + S Q D +
Sbjct: 2136 PGELVTMVC----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 2191
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
V S GV A R L+V P +E Q +V+ V +G + L C
Sbjct: 2192 TCVAASPAGV-ADRNFTLQVQVPPV----------LEPVEFQNDVV---VVRGSLVELPC 2237
Query: 288 AADSQPPATLSWVLQ-DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
A P +SW+ + +LS S GP L+L V AGDSG Y+C A + G ++
Sbjct: 2238 EARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEARRH 2294
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L+V PP +E+ G T L + G + L+C +P ++W +
Sbjct: 2295 FQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 2341
Query: 407 GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLG 466
GQ + + + L ++ G +TC A+ P G+ S + V G G
Sbjct: 2342 GQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 2398
Query: 467 AALGAGVAALLAFCS 481
+G L+ CS
Sbjct: 2399 FVVGLAPGQLVLECS 2413
Score = 71.6 bits (174), Expect = 2e-12
Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG----PRTLGLELRGVRAGDSGRYTCRAEN 338
+RL C A P TL W+ +S + G P L L RA DSGRY+C A +
Sbjct: 804 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 863
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
+G +Q + L V PP LG ++ V+ +S+ L C +H+ PP
Sbjct: 864 AVGEDRQDVVLQVHMPP---------------SILGEELNVSVVANESVALECQSHAMPP 908
Query: 399 ARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
LSW + G+ + P +D +L++ + G +TC A + G +L+V
Sbjct: 909 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967
Score = 66.6 bits (161), Expect = 6e-11
Identities = 53/191 (27%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGD- 328
G ++ G+ + L C A P TLSW + ++ S+ T G LR G+
Sbjct: 410 GRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEA 469
Query: 329 -SGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSL 387
SG Y+C A + G + VQ PP+ L V E LG T++ GQ L
Sbjct: 470 SSGLYSCVASSPAGEAVLQYSVEVQVPPQLL----------VAEGLGQVTTIV---GQPL 516
Query: 388 RLVCVTHSSPPARLSWTRWG----QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
L C SP + W + G + G S L + ++++H G F C A + G
Sbjct: 517 ELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 576
Query: 444 SQHVSLSLSVH 454
+ + +SVH
Sbjct: 577 TAGAEVEVSVH 587
Score = 66.2 bits (160), Expect = 8e-11
Identities = 86/337 (25%), Positives = 141/337 (41%), Gaps = 40/337 (11%)
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
G + +H LS L T L D E T+ P+++IC AF P+P+ +W
Sbjct: 1332 GEKTKHFQLS--VLLAPTILGGAEDSADEEVTVTVNNPISLICEA-LAF---PSPNITWM 1385
Query: 195 --GAALSPRRT---RPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAY 249
GA R P T +L+ + ++ TC V + + A + + V
Sbjct: 1386 KDGAPFEASRNIQLLPGTHGLQILN---AQKEDAGQYTCVV--TNELGEAVKNYHVEVLI 1440
Query: 250 APKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS 309
P SIS D+ + V ++ + L L C + + PP T+ W + ++ S
Sbjct: 1441 PP-----SISKDDPLG---EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPS 1492
Query: 310 HPWGPRTLG----LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQA 365
+ LG L+++ + DSGRY C A N G Q ++ +Q PP +V A
Sbjct: 1493 SRL--QVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSA 1550
Query: 366 NRTVL----ENLGNGTSL-PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGP----SQPS 416
+L E G T ++E L C T++ PP L+W R Q + S
Sbjct: 1551 AFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1610
Query: 417 DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
VL++P ++ E+ G ++C A + +G + L V
Sbjct: 1611 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1647
Score = 63.2 bits (152), Expect = 7e-10
Identities = 51/185 (27%), Positives = 77/185 (41%), Gaps = 22/185 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS----HPWGPRTLGLELRGVRAGDSGRY 332
V + ++LLC A P ++W +L +S + G R L +L ++ D+G Y
Sbjct: 323 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVY 380
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC+A N +G+ ++A L V PP T+ G + + G+ + L CV
Sbjct: 381 TCKASNAVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECV 428
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P LSW G V S S D VL L G ++C A P G +
Sbjct: 429 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 488
Query: 449 LSLSV 453
S+ V
Sbjct: 489 YSVEV 493
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 22/196 (11%)
Query: 267 ELQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP----WGPRTLGLEL 321
E +G V Y E+ + L C ++ PP L+W +D+ LS+ G R L + L
Sbjct: 1560 EARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPL 1619
Query: 322 RGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 381
VRA ++GRY+C+A N +G +L V PP V++ V E N +S
Sbjct: 1620 --VRAENAGRYSCKASNEVGEDWLHYELLVLTPP----VILGDTEELVEEVTVNASS--- 1670
Query: 382 LEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCH 437
++ L C +P +SW + G PS D VL++ ++ + C
Sbjct: 1671 ----TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCV 1726
Query: 438 AQHPLGSQHVSLSLSV 453
A++ GS +L V
Sbjct: 1727 AENQAGSAEKLFTLRV 1742
Score = 60.5 bits (145), Expect = 4e-09
Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 24/194 (12%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS---HPWGPRTLGLELRGVRA 326
G + + V + + L C + + PP LSW R L H + L L++
Sbjct: 884 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVDRADV 942
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G YTC A N+ G ++ +L+V P + L +L V EG
Sbjct: 943 WDAGHYTCEALNQAGRSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHP 988
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPG-VLELPPIQMEHEGEFTCHAQH 440
L C P ++SW + GQ + G S G +L L Q+ EG +TC +
Sbjct: 989 TSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN 1048
Query: 441 PLGSQHVSLSLSVH 454
+G+ L L VH
Sbjct: 1049 VVGNSSQDLQLEVH 1062
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/175 (24%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGS 342
L C A +PP T++W + + + + G L + +A +GRY+C AEN G
Sbjct: 1087 LECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 1146
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
++ +LSV PPE ++ +L T++ L L+C PP +
Sbjct: 1147 AERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1194
Query: 403 WTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
W R + V P + + +L++ Q + G ++C A + G + S+ V
Sbjct: 1195 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1249
Score = 58.9 bits (141), Expect = 1e-08
Identities = 79/318 (24%), Positives = 123/318 (38%), Gaps = 41/318 (12%)
Query: 149 FLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA-----PSFSW--TGAALSPR 201
+L L P V + +T E + VTV + + CPA P+ SW G SP
Sbjct: 1640 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 1698
Query: 202 RTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHD 261
VL + + C + + SA++ LRV P+ I + +
Sbjct: 1699 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPR--IAGLDLE 1754
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGL 319
+A+ L +V L C + P ++W + LS P T L
Sbjct: 1755 QVTAI-LNSSV-----------SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1802
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
+L R DSG YTC A N G Q+ + LSV PP QA R G ++
Sbjct: 1803 QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQDAV 1851
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFT 435
V G L C T + P ++W + GQ + +Q + LE+ Q+ +G ++
Sbjct: 1852 LVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1911
Query: 436 CHAQHPLGSQHVSLSLSV 453
C + G + +L+V
Sbjct: 1912 CKVSNVAGEAVRTFTLTV 1929
Score = 57.0 bits (136), Expect = 5e-08
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 22/193 (11%)
Query: 266 LELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVR 325
+E G L + G + LLC A P ++W + L+ T R +R
Sbjct: 2305 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRAT-----RVLR 2359
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+G YTC AE+ G+ +++ + VQ PP +V + L G
Sbjct: 2360 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPN----IVGPRGPRFVVGLAPG--------- 2406
Query: 386 SLRLVCVTHSSPPARLSWTRWG----QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHP 441
L L C + P +++W R G + P L+L + G+++C A++
Sbjct: 2407 QLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA 2466
Query: 442 LGSQHVSLSLSVH 454
GS V+ + +H
Sbjct: 2467 AGSTSVAFRVEIH 2479
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 19/177 (10%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRL 340
L LLC A PP + W + +S G L++ + DSG Y+C A N
Sbjct: 1179 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1238
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G ++ + V PP +EN + VL+GQ+ L+C P +
Sbjct: 1239 GEARRNFSVEVLVPPS-------------IENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1285
Query: 401 LSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
L+W + G+ + D +L++ + G ++C A + +G + LSV
Sbjct: 1286 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1342
Score = 54.7 bits (130), Expect = 2e-07
Identities = 90/387 (23%), Positives = 132/387 (34%), Gaps = 61/387 (15%)
Query: 83 GAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 142
G PVA +N+SR + R + G+ G S V E Y V+ V
Sbjct: 443 GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPPQ 498
Query: 143 FLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRR 202
L +VT + +P + +P G PV I W PA + G ++ +
Sbjct: 499 LLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWLQNGRPAEELA--GVQVASQG 551
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
T H + DH C A+ V + +AP L + I +
Sbjct: 552 TTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYH 603
Query: 263 TSALELQGNVIYLE--VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT---- 316
+ V +G A +PP W S WG T
Sbjct: 604 WGXEHHSSFPAACDPPVHRGW------GAHPKPPLVEGWC------SPGSLWGEPTGIPV 651
Query: 317 -----LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
L++ V D G YTC A N G ++ + L V PP + N+ VLE
Sbjct: 652 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEPGPVNKAVLE 708
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQ 427
N S+ L C+ PP +SW + Q V G + D VL + Q
Sbjct: 709 N------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 756
Query: 428 MEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ G + C A + GS + L V+
Sbjct: 757 LSDAGSYRCVASNVAGSTELRYGLRVN 783
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/183 (28%), Positives = 70/183 (38%), Gaps = 32/183 (17%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA-----GDSGRYTCRAENR 339
L C A PP +SW + +SS W T+ ++ R +R D+G Y C A N
Sbjct: 714 LECLASGVPPPDVSWFKGHQPVSS---WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 770
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
GS + L V PP R L G PVL +RL C +P
Sbjct: 771 AGSTELRYGLRVNVPP-----------RITLPPSLPG---PVLVNTPVRLTCNATGAPSP 816
Query: 400 RLSWTRWGQTVGPSQPSDPG--------VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
L W + G V P+ PG VL L + G ++C A +G + L
Sbjct: 817 TLMWLKDGNPVSPA--GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 874
Query: 452 SVH 454
VH
Sbjct: 875 QVH 877
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 16/175 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLS--SSHPWGPRTLGLELRGVRAGDSGRY 332
++V GQ L+C P L+W R L+ +H P + L++ +G Y
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1323
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N +G + + LSV P L A+ V + N S L+C
Sbjct: 1324 SCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS----------LICE 1373
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD--PGV--LELPPIQMEHEGEFTCHAQHPLG 443
+ P ++W + G S+ PG L++ Q E G++TC + LG
Sbjct: 1374 ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1428
Score = 53.5 bits (127), Expect = 5e-07
Identities = 79/309 (25%), Positives = 120/309 (38%), Gaps = 52/309 (16%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V++P T+ Q + + C PAP+ SW+ GA L R + S L
Sbjct: 2662 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 2721
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
+ H TC S GV A + V L V +P ++ +V+
Sbjct: 2722 EIGQALPIHAGRYTCSARNSA-GV-AHKHVFLTVQASP-------------VVKPLPSVV 2766
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-GLELRGVRAG--DSG 330
++ L C A P T++W Q L+ + + L G +LR A D+G
Sbjct: 2767 RAVAEEEVLLP--CEASGIPRPTITW--QKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2822
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 2823 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 2867
Query: 391 CVTHSSPPARLSWTRWGQTVGPS------QPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C SP ++W + GQ V + QPS G L + ++ + G +TC A++ +G
Sbjct: 2868 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 2925
Query: 445 QHVSLSLSV 453
+ L++
Sbjct: 2926 ARRRVHLTI 2934
Score = 53.1 bits (126), Expect = 7e-07
Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENR 339
G L L CAA P + W + DR ++ L+ V DSG Y C AENR
Sbjct: 2952 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 3011
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
+G Q + V+ P V+ +A ++E +G S++L CV P
Sbjct: 3012 VGRTQAVSFVHVKEAP----VLQGEAFSYLVEPVGG----------SIQLDCVVRGDPVP 3057
Query: 400 RLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
+ W + G + S G L + + + G + C A++ +G
Sbjct: 3058 DIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 3104
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 23/175 (13%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSG 330
L +G L C A P ++W + +S + G T+ L ++ + D+G
Sbjct: 2856 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE--GKFTIQPSGELLVKNLEGQDAG 2913
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
YTC AEN +G ++ + L++ P V L SL + G L L
Sbjct: 2914 TYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL--GDRLWLR 2958
Query: 391 CVTHSSPPARLSWTRWGQ--TVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
C SP R+ WT + T G S+ L+ + E G + C A++ +G
Sbjct: 2959 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013
Score = 50.4 bits (119), Expect = 5e-06
Identities = 53/194 (27%), Positives = 75/194 (38%), Gaps = 35/194 (18%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL--------GLELRGVRA 326
+ V Q L C AD P +SW +DRV P PR+ L ++ V A
Sbjct: 2491 VNVSVNQTALLPCQADGVPAPLVSW-RKDRV-----PLDPRSPRFEILPEGSLRIQPVLA 2544
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G Y C A N GS +Q DL V PP + S +N T+ + P L
Sbjct: 2545 QDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TPAL---- 2591
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV------GPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
L C SP + W + GQ + G + L L + +F C +
Sbjct: 2592 --LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2649
Query: 441 PLGSQHVSLSLSVH 454
+G H ++VH
Sbjct: 2650 EVGEAHRLYQVTVH 2663
Score = 50.1 bits (118), Expect = 6e-06
Identities = 56/216 (25%), Positives = 79/216 (36%), Gaps = 22/216 (10%)
Query: 268 LQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVR 325
LQG YL G ++L C P + W+ L SH G L +
Sbjct: 3029 LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTE 3088
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+GRY C AEN +G ++ + L +Q P V Q + V G
Sbjct: 3089 RDDAGRYQCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGD 3133
Query: 386 SLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPL 442
+ L C P + W + GQ + S + G L L ++ G + C A + L
Sbjct: 3134 DVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLL 3193
Query: 443 GSQHVSLSLSVHWKLEHGGGLGLGAALGA--GVAAL 476
GS L V + + G G G GVA L
Sbjct: 3194 GSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATL 3229
Score = 49.7 bits (117), Expect = 8e-06
Identities = 49/188 (26%), Positives = 69/188 (36%), Gaps = 22/188 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWGPRTLGLELRGVRAGDS 329
L V++G L C P +SW + L H L L L +
Sbjct: 981 LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 1039
Query: 330 GRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
G YTC N +G+ Q L L V PP+ + T + V++ L
Sbjct: 1040 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 1087
Query: 390 VCVTHSSPPARLSWTRWGQTVGPS---QPSDPG-VLELPPIQMEHEGEFTCHAQHPLGSQ 445
C PP ++W R GQ VG Q + G L + Q H G ++C A++ G
Sbjct: 1088 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1147
Query: 446 HVSLSLSV 453
LSV
Sbjct: 1148 ERKFELSV 1155
Score = 49.3 bits (116), Expect = 1e-05
Identities = 65/294 (22%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTD 225
+L PG P+ ++C + P P+ +W + R ++ VL D
Sbjct: 2315 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVLRV------RDAG 2364
Query: 226 LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRL 285
L + S G + +++ R+RV P + + +G + + GQ + L
Sbjct: 2365 LYTCLAESPAG-AIEKSFRVRVQAPP------------NIVGPRGPRFVVGLAPGQLV-L 2410
Query: 286 LCAADSQPPATLSWVLQDRVLSS-SHPWGP-RTLGLELRGVRAGDSGRYTCRAENRLGSQ 343
C+ +++P ++W VL +H P R L+L+ + DSG Y+C A N GS
Sbjct: 2411 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 2470
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
A + + P +R N +V Q+ L C P +SW
Sbjct: 2471 SVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLVSW 2515
Query: 404 TRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+ + P P G L + P+ + G + C A + GS L V
Sbjct: 2516 RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 2569
Score = 46.6 bits (109), Expect = 7e-05
Identities = 71/320 (22%), Positives = 110/320 (34%), Gaps = 55/320 (17%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWTG--AALSPRRTRP 205
T++ + +++ T+ G P + V A C PAP SW L PR R
Sbjct: 2470 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRL----RVAYAPKDLIISISHD 261
L P C S R +R+ +A +P +L ++
Sbjct: 2530 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA--- 2586
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---- 317
+T AL L C A P + W + L G L
Sbjct: 2587 HTPAL------------------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2628
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377
L L DS ++ C N +G + ++V PP + Q + TV
Sbjct: 2629 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT---IADDQTDFTVT------M 2679
Query: 378 SLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGE 433
PV+ L C + P +SW++ G +G + S G LE+ H G
Sbjct: 2680 MAPVV------LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 2733
Query: 434 FTCHAQHPLGSQHVSLSLSV 453
+TC A++ G H + L+V
Sbjct: 2734 YTCSARNSAGVAHKHVFLTV 2753
Score = 46.2 bits (108), Expect = 9e-05
Identities = 43/170 (25%), Positives = 66/170 (38%), Gaps = 20/170 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTC 334
V+ G L C D+ P T++W + L + G LE++ + D G Y+C
Sbjct: 1853 VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSC 1912
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
+ N G + L+VQ PP EN T + + G L L C
Sbjct: 1913 KVSNVAGEAVRTFTLTVQVPP-------------TFENPKTET-VSQVAGSPLVLTCDVS 1958
Query: 395 SSPPARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQH 440
P ++W + V S S G L+L +Q G +TC A++
Sbjct: 1959 GVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 2008
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 26/185 (14%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG------LELRGVRAGDSGRYT 333
G + L C P + W +DR P GP L + G GD GRY
Sbjct: 232 GADVELQCWTSGVPTPQVEWT-KDR--QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQ 288
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A + G Q + L V PP + +N T + V+E ++L+C
Sbjct: 289 CVAFSPAGQQARDFQLRVHAPP-----TIWGSNET--------GEVAVMEDHLVQLLCEA 335
Query: 394 HSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
P ++W + G + S L+L Q G +TC A + +G+ +
Sbjct: 336 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 395
Query: 450 SLSVH 454
L V+
Sbjct: 396 RLDVY 400
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 24/141 (17%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---GLELRGVRAGDSGR 331
+ V+ G + L C A +P T+ W+ + L +S RTL L L V GD+G
Sbjct: 3127 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL--RTLPDGSLWLENVETGDAGT 3184
Query: 332 YTCRAENRLGSQQQALDLSVQYPPE-----------NLRVMVSQANRTVLENLGNGTS-- 378
Y C A N LGS L V+ P+ + V+ N +V++ +G S
Sbjct: 3185 YDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEAHSGVSSI 3244
Query: 379 ------LPVLEGQSLRLVCVT 393
+P G +R++ VT
Sbjct: 3245 HSSIRHVPANVGPLMRVLVVT 3265
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 13/93 (13%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L L V DSG Y C+A N +GS + L V PP + G +
Sbjct: 59 LFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPS-------------IREDGRKAN 105
Query: 379 LPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVG 411
+ + GQSL L C + P + W + Q VG
Sbjct: 106 VSGMAGQSLTLECDANGFPVPEIVWLKDAQLVG 138
Score = 40.8 bits (94), Expect = 0.004
Identities = 74/304 (24%), Positives = 103/304 (33%), Gaps = 62/304 (20%)
Query: 187 PAPSFSWT-GAALSPRRTRPSTSHF---SVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRT 242
P P +W G + P +P + S+ + SP D D C + + S R
Sbjct: 30 PKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSG-DYECQA--TNEVGSTSRR 86
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQ 302
+L V Y P SI D A + GQ L L C A+ P + W+
Sbjct: 87 AKL-VVYVPP----SIREDGRKA--------NVSGMAGQSLTLECDANGFPVPEIVWLKD 133
Query: 303 DRVLSSSHPW-------------GPRTL--GLEL------------RGVRAGDSGRYTCR 335
+++ W G R L G L RG +AG S +
Sbjct: 134 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAP 193
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
L +Q PP V+ + A + VL L G + L C T
Sbjct: 194 WXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLG----------LAGADVELQCWTSG 243
Query: 396 SPPARLSWTRWGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLS 450
P ++ WT+ Q V P P D VL + + EG + C A P G Q
Sbjct: 244 VPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQ 303
Query: 451 LSVH 454
L VH
Sbjct: 304 LRVH 307
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 76.6 bits (187), Expect = 6e-14
Identities = 91/364 (25%), Positives = 146/364 (40%), Gaps = 66/364 (18%)
Query: 111 KGSCSLVIRDAQREDEAWYFFRVER--GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLE 168
+G L I++AQ D+ Y +V G VR L+ ++V + P ET+
Sbjct: 3083 RGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT----VQVPPTFENPKT---ETVS 3135
Query: 169 P--GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS-------FTPSP 219
G P+ + C + PAP+ +W L R S++ V+S P
Sbjct: 3136 QVAGSPLVLTCDVSGV----PAPTVTW----LKDRMPVESSAVHGVVSRGGRLQLSRLQP 3187
Query: 220 QDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQK 279
T TC + ++ A++ + V AP+ ++ ++ V +
Sbjct: 3188 AQAGT-YTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH-------------HVLE 3231
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL------GLELRGVRAGDSGRYT 333
GQ +RL C AD QPP ++W+ L GP L L+G+RA D+G YT
Sbjct: 3232 GQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAGAYT 3289
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G + ++V PP T+ + +L G+ + +VC
Sbjct: 3290 CVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMVCPV 3337
Query: 394 HSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
SPP +SW + G + SQ + L + +Q+ G FTC A P G +
Sbjct: 3338 RGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNF 3397
Query: 450 SLSV 453
+L V
Sbjct: 3398 TLQV 3401
Score = 73.9 bits (180), Expect = 4e-13
Identities = 81/315 (25%), Positives = 126/315 (40%), Gaps = 39/315 (12%)
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSP-QDHDTDLT 227
PG+ VT++C + P SW L ++ + H S + S Q D +
Sbjct: 3327 PGELVTMVC----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 3382
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
V S GV A R L+V P +E Q +V+ V +G + L C
Sbjct: 3383 TCVAASPAGV-ADRNFTLQVQVPPV----------LEPVEFQNDVV---VVRGSLVELPC 3428
Query: 288 AADSQPPATLSWVLQ-DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
A P +SW+ + +LS S GP L+L V AGDSG Y+C A + G ++
Sbjct: 3429 EARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEARRH 3485
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L+V PP +E+ G T L + G + L+C +P ++W +
Sbjct: 3486 FQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 3532
Query: 407 GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLG 466
GQ + + + L ++ G +TC A+ P G+ S + V G G
Sbjct: 3533 GQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 3589
Query: 467 AALGAGVAALLAFCS 481
+G L+ CS
Sbjct: 3590 FVVGLAPGQLVLECS 3604
Score = 73.6 bits (179), Expect = 5e-13
Identities = 51/177 (28%), Positives = 78/177 (44%), Gaps = 17/177 (9%)
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAE 337
+G +++ C+A P +SW + + L G L ++GV D+G Y+C+A
Sbjct: 621 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
N +G+ Q+ + L PP VS N VL V G+ LVC P
Sbjct: 681 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 725
Query: 398 PARLSWTRWG-QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
P R+ W R G + + + S G L +P Q G +TC A + LG + L+V
Sbjct: 726 PPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 71.6 bits (174), Expect = 2e-12
Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG----PRTLGLELRGVRAGDSGRYTCRAEN 338
+RL C A P TL W+ +S + G P L L RA DSGRY+C A +
Sbjct: 1995 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 2054
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
+G +Q + L V PP LG ++ V+ +S+ L C +H+ PP
Sbjct: 2055 AVGEDRQDVVLQVHMPP---------------SILGEELNVSVVANESVALECQSHAMPP 2099
Query: 399 ARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
LSW + G+ + P +D +L++ + G +TC A + G +L+V
Sbjct: 2100 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 2158
Score = 69.7 bits (169), Expect = 7e-12
Identities = 81/294 (27%), Positives = 111/294 (37%), Gaps = 55/294 (18%)
Query: 187 PAPSFSWT-GAALSPRRTRPSTSHF---SVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRT 242
P P +W G + P +P + S+ + SP D D C + + S R
Sbjct: 1234 PKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSG-DYECQA--TNEVGSTSRR 1290
Query: 243 VRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQ 302
+L V Y P SI D A + GQ L L C A+ P + W+
Sbjct: 1291 AKL-VVYVPP----SIREDGRKA--------NVSGMAGQSLTLECDANGFPVPEIVWLKD 1337
Query: 303 DRVLSSSHPW-------------GPRTL----GLELRGVRAGDSGRYTCRAENRLGSQQQ 345
+++ W G R L L ++ GDSG Y+CRAEN+ G+ Q+
Sbjct: 1338 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQR 1397
Query: 346 ALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTR 405
L V PP L +Q E LG L G + L C T P ++ WT+
Sbjct: 1398 DFHLLVLTPPSVLGAGAAQ------EVLG-------LAGADVELQCWTSGVPTPQVEWTK 1444
Query: 406 WGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
Q V P P D VL + + EG + C A P G Q L VH
Sbjct: 1445 DRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVH 1498
Score = 66.6 bits (161), Expect = 6e-11
Identities = 53/191 (27%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGD- 328
G ++ G+ + L C A P TLSW + ++ S+ T G LR G+
Sbjct: 1601 GRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEA 1660
Query: 329 -SGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSL 387
SG Y+C A + G + VQ PP+ L V E LG T++ GQ L
Sbjct: 1661 SSGLYSCVASSPAGEAVLQYSVEVQVPPQLL----------VAEGLGQVTTIV---GQPL 1707
Query: 388 RLVCVTHSSPPARLSWTRWG----QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
L C SP + W + G + G S L + ++++H G F C A + G
Sbjct: 1708 ELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 1767
Query: 444 SQHVSLSLSVH 454
+ + +SVH
Sbjct: 1768 TAGAEVEVSVH 1778
Score = 66.2 bits (160), Expect = 8e-11
Identities = 86/337 (25%), Positives = 141/337 (41%), Gaps = 40/337 (11%)
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
G + +H LS L T L D E T+ P+++IC AF P+P+ +W
Sbjct: 2523 GEKTKHFQLS--VLLAPTILGGAEDSADEEVTVTVNNPISLICEA-LAF---PSPNITWM 2576
Query: 195 --GAALSPRRT---RPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAY 249
GA R P T +L+ + ++ TC V + + A + + V
Sbjct: 2577 KDGAPFEASRNIQLLPGTHGLQILN---AQKEDAGQYTCVV--TNELGEAVKNYHVEVLI 2631
Query: 250 APKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS 309
P SIS D+ + V ++ + L L C + + PP T+ W + ++ S
Sbjct: 2632 PP-----SISKDDPLG---EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPS 2683
Query: 310 HPWGPRTLG----LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQA 365
+ LG L+++ + DSGRY C A N G Q ++ +Q PP +V A
Sbjct: 2684 SRL--QVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSA 2741
Query: 366 NRTVL----ENLGNGTSL-PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGP----SQPS 416
+L E G T ++E L C T++ PP L+W R Q + S
Sbjct: 2742 AFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 2801
Query: 417 DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
VL++P ++ E+ G ++C A + +G + L V
Sbjct: 2802 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 2838
Score = 63.2 bits (152), Expect = 7e-10
Identities = 51/185 (27%), Positives = 77/185 (41%), Gaps = 22/185 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS----HPWGPRTLGLELRGVRAGDSGRY 332
V + ++LLC A P ++W +L +S + G R L +L ++ D+G Y
Sbjct: 1514 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVY 1571
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC+A N +G+ ++A L V PP T+ G + + G+ + L CV
Sbjct: 1572 TCKASNAVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECV 1619
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P LSW G V S S D VL L G ++C A P G +
Sbjct: 1620 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 1679
Query: 449 LSLSV 453
S+ V
Sbjct: 1680 YSVEV 1684
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/169 (29%), Positives = 68/169 (40%), Gaps = 25/169 (14%)
Query: 303 DRVLSSSHPWGPRTL----GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENL 358
+R+ S + W L L L V+ GDSG Y C A N GS L VQ PP+
Sbjct: 1064 NRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQ-- 1121
Query: 359 RVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP 418
V R L VL G++L L CV +P +LSW++ G + P
Sbjct: 1122 ---VQPGPRV----------LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQ-- 1166
Query: 419 GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV----HWKLEHGGGL 463
G + I+ G + C A + G + L V HW + GL
Sbjct: 1167 GSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGL 1215
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 22/196 (11%)
Query: 267 ELQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP----WGPRTLGLEL 321
E +G V Y E+ + L C ++ PP L+W +D+ LS+ G R L + L
Sbjct: 2751 EARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPL 2810
Query: 322 RGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 381
VRA ++GRY+C+A N +G +L V PP V++ V E N +S
Sbjct: 2811 --VRAENAGRYSCKASNEVGEDWLHYELLVLTPP----VILGDTEELVEEVTVNASS--- 2861
Query: 382 LEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCH 437
++ L C +P +SW + G PS D VL++ ++ + C
Sbjct: 2862 ----TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCV 2917
Query: 438 AQHPLGSQHVSLSLSV 453
A++ GS +L V
Sbjct: 2918 AENQAGSAEKLFTLRV 2933
Score = 60.5 bits (145), Expect = 4e-09
Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 24/194 (12%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS---HPWGPRTLGLELRGVRA 326
G + + V + + L C + + PP LSW R L H + L L++
Sbjct: 2075 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVDRADV 2133
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G YTC A N+ G ++ +L+V P + L +L V EG
Sbjct: 2134 WDAGHYTCEALNQAGHSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHP 2179
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPG-VLELPPIQMEHEGEFTCHAQH 440
L C P ++SW + GQ + G S G +L L Q+ EG +TC +
Sbjct: 2180 TSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN 2239
Query: 441 PLGSQHVSLSLSVH 454
+G+ L L VH
Sbjct: 2240 VVGNSSQDLQLEVH 2253
Score = 59.7 bits (143), Expect = 8e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 24/186 (12%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTC 334
L+V G+ L L C A+ P LSW VL P G + +R D+GRY C
Sbjct: 1129 LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQG----SVHFAAIRTSDAGRYRC 1184
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G ++L V PP + +LE + G++ L C
Sbjct: 1185 EASNSAGVDAWEVELRVLEPPH----WGADETSGLLERVA---------GENASLPCPAR 1231
Query: 395 SSPPARLSWTRWGQTVGP--SQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+P +++W R G + P QP + G L L + G++ C A + +GS
Sbjct: 1232 GTPKPQVTW-RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRR 1290
Query: 449 LSLSVH 454
L V+
Sbjct: 1291 AKLVVY 1296
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/175 (24%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGS 342
L C A +PP T++W + + + + G L + +A +GRY+C AEN G
Sbjct: 2278 LECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 2337
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
++ +LSV PPE ++ +L T++ L L+C PP +
Sbjct: 2338 AERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 2385
Query: 403 WTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
W R + V P + + +L++ Q + G ++C A + G + S+ V
Sbjct: 2386 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 2440
Score = 58.9 bits (141), Expect = 1e-08
Identities = 79/318 (24%), Positives = 123/318 (38%), Gaps = 41/318 (12%)
Query: 149 FLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA-----PSFSW--TGAALSPR 201
+L L P V + +T E + VTV + + CPA P+ SW G SP
Sbjct: 2831 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 2889
Query: 202 RTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHD 261
VL + + C + + SA++ LRV P+ I + +
Sbjct: 2890 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPR--IAGLDLE 2945
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGL 319
+A+ L +V L C + P ++W + LS P T L
Sbjct: 2946 QVTAI-LNSSV-----------SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 2993
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
+L R DSG YTC A N G Q+ + LSV PP QA R G ++
Sbjct: 2994 QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQDAV 3042
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFT 435
V G L C T + P ++W + GQ + +Q + LE+ Q+ +G ++
Sbjct: 3043 LVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 3102
Query: 436 CHAQHPLGSQHVSLSLSV 453
C + G + +L+V
Sbjct: 3103 CKVSNVAGEAVRTFTLTV 3120
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/187 (26%), Positives = 75/187 (40%), Gaps = 26/187 (13%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V G+ L+C A PP + W + + P G + L + + D+G YTCRA
Sbjct: 709 VAVGEEAVLVCEASGVPPPRVIWYRGGLEMILA-PEGSSSGKLRIPAAQERDAGTYTCRA 767
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
N LG + L+V + P+ +++ R V L G+S L C
Sbjct: 768 VNELGDASAEIQLAVGHAPQ-----LTELPRDVTVEL----------GRSALLACRATGR 812
Query: 397 PPARLSWTRW-GQTVG---------PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
PP ++W R GQ +G S+ D GVL + E + + C A++ G
Sbjct: 813 PPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ 872
Query: 447 VSLSLSV 453
L V
Sbjct: 873 AEARLIV 879
Score = 57.0 bits (136), Expect = 5e-08
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 22/193 (11%)
Query: 266 LELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVR 325
+E G L + G + LLC A P ++W + L+ T R +R
Sbjct: 3496 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRAT-----RVLR 3550
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+G YTC AE+ G+ +++ + VQ PP +V + L G
Sbjct: 3551 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPN----IVGPRGPRFVVGLAPG--------- 3597
Query: 386 SLRLVCVTHSSPPARLSWTRWG----QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHP 441
L L C + P +++W R G + P L+L + G+++C A++
Sbjct: 3598 QLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA 3657
Query: 442 LGSQHVSLSLSVH 454
GS V+ + +H
Sbjct: 3658 AGSTSVAFRVEIH 3670
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 19/177 (10%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRL 340
L LLC A PP + W + +S G L++ + DSG Y+C A N
Sbjct: 2370 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 2429
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G ++ + V PP +EN + VL+GQ+ L+C P +
Sbjct: 2430 GEARRNFSVEVLVPPS-------------IENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 2476
Query: 401 LSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
L+W + G+ + D +L++ + G ++C A + +G + LSV
Sbjct: 2477 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 2533
Score = 54.7 bits (130), Expect = 2e-07
Identities = 90/387 (23%), Positives = 132/387 (34%), Gaps = 61/387 (15%)
Query: 83 GAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 142
G PVA +N+SR + R + G+ G S V E Y V+ V
Sbjct: 1634 GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPPQ 1689
Query: 143 FLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRR 202
L +VT + +P + +P G PV I W PA + G ++ +
Sbjct: 1690 LLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWLQNGRPAEELA--GVQVASQG 1742
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
T H + DH C A+ V + +AP L + I +
Sbjct: 1743 TTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYH 1794
Query: 263 TSALELQGNVIYLE--VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT---- 316
+ V +G A +PP W S WG T
Sbjct: 1795 WGXEHHSSFPAACDPPVHRGW------GAHPKPPLVEGWC------SPGSLWGEPTGIPV 1842
Query: 317 -----LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
L++ V D G YTC A N G ++ + L V PP + N+ VLE
Sbjct: 1843 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEPGPVNKAVLE 1899
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQ 427
N S+ L C+ PP +SW + Q V G + D VL + Q
Sbjct: 1900 N------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 1947
Query: 428 MEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ G + C A + GS + L V+
Sbjct: 1948 LSDAGSYRCVASNVAGSTELRYGLRVN 1974
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/183 (28%), Positives = 70/183 (38%), Gaps = 32/183 (17%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA-----GDSGRYTCRAENR 339
L C A PP +SW + +SS W T+ ++ R +R D+G Y C A N
Sbjct: 1905 LECLASGVPPPDVSWFKGHQPVSS---WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 1961
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
GS + L V PP R L G PVL +RL C +P
Sbjct: 1962 AGSTELRYGLRVNVPP-----------RITLPPSLPG---PVLVNTPVRLTCNATGAPSP 2007
Query: 400 RLSWTRWGQTVGPSQPSDPG--------VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
L W + G V P+ PG VL L + G ++C A +G + L
Sbjct: 2008 TLMWLKDGNPVSPA--GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 2065
Query: 452 SVH 454
VH
Sbjct: 2066 QVH 2068
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 16/175 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLS--SSHPWGPRTLGLELRGVRAGDSGRY 332
++V GQ L+C P L+W R L+ +H P + L++ +G Y
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 2514
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N +G + + LSV P L A+ V + N S L+C
Sbjct: 2515 SCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS----------LICE 2564
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD--PGV--LELPPIQMEHEGEFTCHAQHPLG 443
+ P ++W + G S+ PG L++ Q E G++TC + LG
Sbjct: 2565 ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 2619
Score = 53.5 bits (127), Expect = 5e-07
Identities = 79/309 (25%), Positives = 120/309 (38%), Gaps = 52/309 (16%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V++P T+ Q + + C PAP+ SW+ GA L R + S L
Sbjct: 3853 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 3912
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
+ H TC S GV A + V L V +P ++ +V+
Sbjct: 3913 EIGQALPIHAGRYTCSARNSA-GV-AHKHVFLTVQASP-------------VVKPLPSVV 3957
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-GLELRGVRAG--DSG 330
++ L C A P T++W Q L+ + + L G +LR A D+G
Sbjct: 3958 RAVAEEEVLLP--CEASGIPRPTITW--QKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 4013
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 4014 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 4058
Query: 391 CVTHSSPPARLSWTRWGQTVGPS------QPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C SP ++W + GQ V + QPS G L + ++ + G +TC A++ +G
Sbjct: 4059 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 4116
Query: 445 QHVSLSLSV 453
+ L++
Sbjct: 4117 ARRRVHLTI 4125
Score = 53.1 bits (126), Expect = 7e-07
Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENR 339
G L L CAA P + W + DR ++ L+ V DSG Y C AENR
Sbjct: 4143 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 4202
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
+G Q + V+ P V+ +A ++E +G S++L CV P
Sbjct: 4203 VGRTQAVSFVHVKEAP----VLQGEAFSYLVEPVGG----------SIQLDCVVRGDPVP 4248
Query: 400 RLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
+ W + G + S G L + + + G + C A++ +G
Sbjct: 4249 DIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 4295
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 23/175 (13%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSG 330
L +G L C A P ++W + +S + G T+ L ++ + D+G
Sbjct: 4047 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE--GKFTIQPSGELLVKNLEGQDAG 4104
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
YTC AEN +G ++ + L++ P V L SL + G L L
Sbjct: 4105 TYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL--GDRLWLR 4149
Query: 391 CVTHSSPPARLSWTRWGQ--TVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
C SP R+ WT + T G S+ L+ + E G + C A++ +G
Sbjct: 4150 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 20/180 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT--LGLELRGVRAGDSGRYTC 334
V G+ L C + P L+WV RVL +S + L LE+ G+ D GRY C
Sbjct: 528 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQC 587
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G + ++ L V+ P+ V + + +S +G +++ C
Sbjct: 588 VASNANGVTRASVWLLVREAPQ---VSI------------HTSSQHFSQGVEVKVSCSAS 632
Query: 395 SSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
P +SW+R Q + G L + + E G ++C A + +G+ +++L
Sbjct: 633 GYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 692
Score = 50.4 bits (119), Expect = 5e-06
Identities = 53/194 (27%), Positives = 75/194 (38%), Gaps = 35/194 (18%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL--------GLELRGVRA 326
+ V Q L C AD P +SW +DRV P PR+ L ++ V A
Sbjct: 3682 VNVSVNQTALLPCQADGVPAPLVSW-RKDRV-----PLDPRSPRFEILPEGSLRIQPVLA 3735
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G Y C A N GS +Q DL V PP + S +N T+ + P L
Sbjct: 3736 QDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TPAL---- 3782
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV------GPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
L C SP + W + GQ + G + L L + +F C +
Sbjct: 3783 --LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 3840
Query: 441 PLGSQHVSLSLSVH 454
+G H ++VH
Sbjct: 3841 EVGEAHRLYQVTVH 3854
Score = 50.1 bits (118), Expect = 6e-06
Identities = 56/216 (25%), Positives = 79/216 (36%), Gaps = 22/216 (10%)
Query: 268 LQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVR 325
LQG YL G ++L C P + W+ L SH G L +
Sbjct: 4220 LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTE 4279
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+GRY C AEN +G ++ + L +Q P V Q + V G
Sbjct: 4280 RDDAGRYQCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGD 4324
Query: 386 SLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPL 442
+ L C P + W + GQ + S + G L L ++ G + C A + L
Sbjct: 4325 DVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLL 4384
Query: 443 GSQHVSLSLSVHWKLEHGGGLGLGAALGA--GVAAL 476
GS L V + + G G G GVA L
Sbjct: 4385 GSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATL 4420
Score = 49.7 bits (117), Expect = 8e-06
Identities = 49/188 (26%), Positives = 69/188 (36%), Gaps = 22/188 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWGPRTLGLELRGVRAGDS 329
L V++G L C P +SW + L H L L L +
Sbjct: 2172 LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 2230
Query: 330 GRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
G YTC N +G+ Q L L V PP+ + T + V++ L
Sbjct: 2231 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 2278
Query: 390 VCVTHSSPPARLSWTRWGQTVGPS---QPSDPG-VLELPPIQMEHEGEFTCHAQHPLGSQ 445
C PP ++W R GQ VG Q + G L + Q H G ++C A++ G
Sbjct: 2279 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 2338
Query: 446 HVSLSLSV 453
LSV
Sbjct: 2339 ERKFELSV 2346
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/186 (25%), Positives = 73/186 (39%), Gaps = 21/186 (11%)
Query: 275 LEVQKGQFLRLLCAA-DSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332
+ V +GQ + L C +P W+ R L R G L L +GRY
Sbjct: 894 VRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRY 953
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N GSQ + ++L VQ PP + + T ++ N EG L CV
Sbjct: 954 SCVATNTAGSQHRDVELVVQVPP--------RIHPTATHHITN-------EGVPASLPCV 998
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P ++WT+ + P S G L + + G + C A + +G
Sbjct: 999 ASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQE 1058
Query: 449 LSLSVH 454
+ LSV+
Sbjct: 1059 MRLSVN 1064
Score = 49.3 bits (116), Expect = 1e-05
Identities = 65/294 (22%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTD 225
+L PG P+ ++C + P P+ +W + R ++ VL D
Sbjct: 3506 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVLRV------RDAG 3555
Query: 226 LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRL 285
L + S G + +++ R+RV P + + +G + + GQ + L
Sbjct: 3556 LYTCLAESPAG-AIEKSFRVRVQAPP------------NIVGPRGPRFVVGLAPGQLV-L 3601
Query: 286 LCAADSQPPATLSWVLQDRVLSS-SHPWGP-RTLGLELRGVRAGDSGRYTCRAENRLGSQ 343
C+ +++P ++W VL +H P R L+L+ + DSG Y+C A N GS
Sbjct: 3602 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 3661
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
A + + P +R N +V Q+ L C P +SW
Sbjct: 3662 SVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLVSW 3706
Query: 404 TRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+ + P P G L + P+ + G + C A + GS L V
Sbjct: 3707 RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 3760
Score = 46.6 bits (109), Expect = 7e-05
Identities = 71/320 (22%), Positives = 110/320 (34%), Gaps = 55/320 (17%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWTG--AALSPRRTRP 205
T++ + +++ T+ G P + V A C PAP SW L PR R
Sbjct: 3661 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRL----RVAYAPKDLIISISHD 261
L P C S R +R+ +A +P +L ++
Sbjct: 3721 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA--- 3777
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---- 317
+T AL L C A P + W + L G L
Sbjct: 3778 HTPAL------------------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 3819
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377
L L DS ++ C N +G + ++V PP + Q + TV
Sbjct: 3820 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT---IADDQTDFTVT------M 3870
Query: 378 SLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGE 433
PV+ L C + P +SW++ G +G + S G LE+ H G
Sbjct: 3871 MAPVV------LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 3924
Query: 434 FTCHAQHPLGSQHVSLSLSV 453
+TC A++ G H + L+V
Sbjct: 3925 YTCSARNSAGVAHKHVFLTV 3944
Score = 46.2 bits (108), Expect = 9e-05
Identities = 43/170 (25%), Positives = 66/170 (38%), Gaps = 20/170 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTC 334
V+ G L C D+ P T++W + L + G LE++ + D G Y+C
Sbjct: 3044 VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSC 3103
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
+ N G + L+VQ PP EN T + + G L L C
Sbjct: 3104 KVSNVAGEAVRTFTLTVQVPP-------------TFENPKTET-VSQVAGSPLVLTCDVS 3149
Query: 395 SSPPARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQH 440
P ++W + V S S G L+L +Q G +TC A++
Sbjct: 3150 GVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 26/185 (14%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG------LELRGVRAGDSGRYT 333
G + L C P + W +DR P GP L + G GD GRY
Sbjct: 1423 GADVELQCWTSGVPTPQVEWT-KDR--QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQ 1479
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A + G Q + L V PP + +N T + V+E ++L+C
Sbjct: 1480 CVAFSPAGQQARDFQLRVHAPP-----TIWGSNET--------GEVAVMEDHLVQLLCEA 1526
Query: 394 HSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
P ++W + G + S L+L Q G +TC A + +G+ +
Sbjct: 1527 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 1586
Query: 450 SLSVH 454
L V+
Sbjct: 1587 RLDVY 1591
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 24/141 (17%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---GLELRGVRAGDSGR 331
+ V+ G + L C A +P T+ W+ + L +S RTL L L V GD+G
Sbjct: 4318 MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL--RTLPDGSLWLENVETGDAGT 4375
Query: 332 YTCRAENRLGSQQQALDLSVQYPPE-----------NLRVMVSQANRTVLENLGNGTS-- 378
Y C A N LGS L V+ P+ + V+ N +V++ +G S
Sbjct: 4376 YDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEAHSGVSSI 4435
Query: 379 ------LPVLEGQSLRLVCVT 393
+P G +R++ VT
Sbjct: 4436 HSSIRHVPANVGPLMRVLVVT 4456
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 76.6 bits (187), Expect = 6e-14
Identities = 91/364 (25%), Positives = 146/364 (40%), Gaps = 66/364 (18%)
Query: 111 KGSCSLVIRDAQREDEAWYFFRVER--GSRVRHSFLSNAFFLKVTALTKKPDVYIPETLE 168
+G L I++AQ D+ Y +V G VR L+ ++V + P ET+
Sbjct: 1801 RGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLT----VQVPPTFENPKT---ETVS 1853
Query: 169 P--GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLS-------FTPSP 219
G P+ + C + PAP+ +W L R S++ V+S P
Sbjct: 1854 QVAGSPLVLTCDVSGV----PAPTVTW----LKDRMPVESSAVHGVVSRGGRLQLSRLQP 1905
Query: 220 QDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQK 279
T TC + ++ A++ + V AP+ ++ ++ V +
Sbjct: 1906 AQAGT-YTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH-------------HVLE 1949
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL------GLELRGVRAGDSGRYT 333
GQ +RL C AD QPP ++W+ L GP L L+G+RA D+G YT
Sbjct: 1950 GQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAGAYT 2007
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G + ++V PP T+ + +L G+ + +VC
Sbjct: 2008 CVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMVCPV 2055
Query: 394 HSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
SPP +SW + G + SQ + L + +Q+ G FTC A P G +
Sbjct: 2056 RGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNF 2115
Query: 450 SLSV 453
+L V
Sbjct: 2116 TLQV 2119
Score = 73.9 bits (180), Expect = 4e-13
Identities = 81/315 (25%), Positives = 126/315 (40%), Gaps = 39/315 (12%)
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSP-QDHDTDLT 227
PG+ VT++C + P SW L ++ + H S + S Q D +
Sbjct: 2045 PGELVTMVC----PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 2100
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
V S GV A R L+V P +E Q +V+ V +G + L C
Sbjct: 2101 TCVAASPAGV-ADRNFTLQVQVPPV----------LEPVEFQNDVV---VVRGSLVELPC 2146
Query: 288 AADSQPPATLSWVLQ-DRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
A P +SW+ + +LS S GP L+L V AGDSG Y+C A + G ++
Sbjct: 2147 EARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEARRH 2203
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
L+V PP +E+ G T L + G + L+C +P ++W +
Sbjct: 2204 FQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD 2250
Query: 407 GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLG 466
GQ + + + L ++ G +TC A+ P G+ S + V G G
Sbjct: 2251 GQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 2307
Query: 467 AALGAGVAALLAFCS 481
+G L+ CS
Sbjct: 2308 FVVGLAPGQLVLECS 2322
Score = 71.6 bits (174), Expect = 2e-12
Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG----PRTLGLELRGVRAGDSGRYTCRAEN 338
+RL C A P TL W+ +S + G P L L RA DSGRY+C A +
Sbjct: 713 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 772
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
+G +Q + L V PP LG ++ V+ +S+ L C +H+ PP
Sbjct: 773 AVGEDRQDVVLQVHMPP---------------SILGEELNVSVVANESVALECQSHAMPP 817
Query: 399 ARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
LSW + G+ + P +D +L++ + G +TC A + G +L+V
Sbjct: 818 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 876
Score = 68.2 bits (165), Expect = 2e-11
Identities = 59/197 (29%), Positives = 79/197 (40%), Gaps = 35/197 (17%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPW-------------GPRTL----GLELR 322
GQ L L C A+ P + W+ +++ W G R L L
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
++ GDSG Y+CRAEN+ G+ Q+ L V PP L +Q E LG L
Sbjct: 93 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQ------EVLG-------L 139
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCH 437
G + L C T P ++ WT+ Q V P P D VL + + EG + C
Sbjct: 140 AGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCV 199
Query: 438 AQHPLGSQHVSLSLSVH 454
A P G Q L VH
Sbjct: 200 AFSPAGQQARDFQLRVH 216
Score = 67.8 bits (164), Expect = 3e-11
Identities = 87/337 (25%), Positives = 142/337 (42%), Gaps = 40/337 (11%)
Query: 136 GSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLEPGQPVTVICVFNWAFKKCPAPSFSWT 194
G + +H LS L T L D E T+ P+++IC AF P+P+ +W
Sbjct: 1241 GEKTKHFQLS--VLLAPTILGGAEDSADEEVTVTVNNPISLICEA-LAF---PSPNITWM 1294
Query: 195 --GAALSPRRT---RPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAY 249
GA R P T +L+ + ++ TC V + + A + + V
Sbjct: 1295 KDGAPFEASRNIQLLPGTHGLQILN---AQKEDAGQYTCVV--TNELGEAVKNYHVEVLI 1349
Query: 250 APKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS 309
P SIS D+ A + V ++ + L L C + + PP T+ W + ++ S
Sbjct: 1350 PP-----SISKDDPLA---EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPS 1401
Query: 310 HPWGPRTLG----LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQA 365
+ LG L+++ + DSGRY C A N G Q ++ +Q PP +V A
Sbjct: 1402 SRL--QVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSA 1459
Query: 366 NRTVL----ENLGNGTSL-PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGP----SQPS 416
+L E G T ++E L C T++ PP L+W R Q + S
Sbjct: 1460 AFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1519
Query: 417 DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
VL++P ++ E+ G ++C A + +G + L V
Sbjct: 1520 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1556
Score = 66.6 bits (161), Expect = 6e-11
Identities = 53/191 (27%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGD- 328
G ++ G+ + L C A P TLSW + ++ S+ T G LR G+
Sbjct: 319 GRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEA 378
Query: 329 -SGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSL 387
SG Y+C A + G + VQ PP+ L V E LG T++ GQ L
Sbjct: 379 SSGLYSCVASSPAGEAVLQYSVEVQVPPQLL----------VAEGLGQVTTIV---GQPL 425
Query: 388 RLVCVTHSSPPARLSWTRWG----QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
L C SP + W + G + G S L + ++++H G F C A + G
Sbjct: 426 ELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 485
Query: 444 SQHVSLSLSVH 454
+ + +SVH
Sbjct: 486 TAGAEVEVSVH 496
Score = 63.2 bits (152), Expect = 7e-10
Identities = 51/185 (27%), Positives = 77/185 (41%), Gaps = 22/185 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS----HPWGPRTLGLELRGVRAGDSGRY 332
V + ++LLC A P ++W +L +S + G R L +L ++ D+G Y
Sbjct: 232 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVY 289
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC+A N +G+ ++A L V PP T+ G + + G+ + L CV
Sbjct: 290 TCKASNAVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECV 337
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P LSW G V S S D VL L G ++C A P G +
Sbjct: 338 ARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQ 397
Query: 449 LSLSV 453
S+ V
Sbjct: 398 YSVEV 402
Score = 62.8 bits (151), Expect = 9e-10
Identities = 53/194 (27%), Positives = 80/194 (41%), Gaps = 24/194 (12%)
Query: 270 GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS---HPWGPRTLGLELRGVRA 326
G + + V + + L C + + PP LSW R L H + L L++
Sbjct: 793 GEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVDRADV 851
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G YTC A N+ G ++ +L+V P + L +L V EG
Sbjct: 852 WDAGHYTCEALNQAGHSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHP 897
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPG-VLELPPIQMEHEGEFTCHAQH 440
RL C P ++SW + GQ + G S G +L L Q+ EG +TC +
Sbjct: 898 TRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN 957
Query: 441 PLGSQHVSLSLSVH 454
+G+ L L VH
Sbjct: 958 VVGNSSQDLQLEVH 971
Score = 62.0 bits (149), Expect = 2e-09
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 22/196 (11%)
Query: 267 ELQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP----WGPRTLGLEL 321
E +G V Y E+ + L C ++ PP L+W +D+ LS+ G R L + L
Sbjct: 1469 EARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPL 1528
Query: 322 RGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 381
VRA ++GRY+C+A N +G +L V PP V++ V E N +S
Sbjct: 1529 --VRAENAGRYSCKASNEVGEDWLHYELLVLTPP----VILGDTEELVEEVTVNASS--- 1579
Query: 382 LEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCH 437
++ L C +P +SW + G PS D VL++ ++ + C
Sbjct: 1580 ----TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCV 1635
Query: 438 AQHPLGSQHVSLSLSV 453
A++ GS +L V
Sbjct: 1636 AENQAGSAEKLFTLRV 1651
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/175 (24%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGS 342
L C A +PP T++W + + + + G L + +A +GRY+C AEN G
Sbjct: 996 LECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 1055
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
++ +LSV PPE ++ +L T++ L L+C PP +
Sbjct: 1056 AERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1103
Query: 403 WTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
W R + V P + + +L++ Q + G ++C A + G + S+ V
Sbjct: 1104 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1158
Score = 58.9 bits (141), Expect = 1e-08
Identities = 79/318 (24%), Positives = 123/318 (38%), Gaps = 41/318 (12%)
Query: 149 FLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPA-----PSFSW--TGAALSPR 201
+L L P V + +T E + VTV + + CPA P+ SW G SP
Sbjct: 1549 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 1607
Query: 202 RTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHD 261
VL + + C + + SA++ LRV P+ I + +
Sbjct: 1608 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPR--IAGLDLE 1663
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGL 319
+A+ L +V L C + P ++W + LS P T L
Sbjct: 1664 QVTAI-LNSSV-----------SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1711
Query: 320 ELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 379
+L R DSG YTC A N G Q+ + LSV PP QA R G ++
Sbjct: 1712 QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQDAV 1760
Query: 380 PVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDP----GVLELPPIQMEHEGEFT 435
V G L C T + P ++W + GQ + +Q + LE+ Q+ +G ++
Sbjct: 1761 LVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYS 1820
Query: 436 CHAQHPLGSQHVSLSLSV 453
C + G + +L+V
Sbjct: 1821 CKVSNVAGEAVRTFTLTV 1838
Score = 57.0 bits (136), Expect = 5e-08
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 22/193 (11%)
Query: 266 LELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVR 325
+E G L + G + LLC A P ++W + L+ T R +R
Sbjct: 2214 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRAT-----RVLR 2268
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+G YTC AE+ G+ +++ + VQ PP +V + L G
Sbjct: 2269 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPN----IVGPRGPRFVVGLAPG--------- 2315
Query: 386 SLRLVCVTHSSPPARLSWTRWG----QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHP 441
L L C + P +++W R G + P L+L + G+++C A++
Sbjct: 2316 QLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA 2375
Query: 442 LGSQHVSLSLSVH 454
GS V+ + +H
Sbjct: 2376 AGSTSVAFRVEIH 2388
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 19/177 (10%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRL 340
L LLC A PP + W + +S G L++ + DSG Y+C A N
Sbjct: 1088 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1147
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G ++ + V PP +EN + VL+GQ+ L+C P +
Sbjct: 1148 GEARRNFSVEVLVPPS-------------IENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1194
Query: 401 LSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
L+W + G+ + D +L++ + G ++C A + +G + LSV
Sbjct: 1195 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1251
Score = 54.7 bits (130), Expect = 2e-07
Identities = 90/387 (23%), Positives = 132/387 (34%), Gaps = 61/387 (15%)
Query: 83 GAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHS 142
G PVA +N+SR + R + G+ G S V E Y V+ V
Sbjct: 352 GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPPQ 407
Query: 143 FLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRR 202
L +VT + +P + +P G PV I W PA + G ++ +
Sbjct: 408 LLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWLQNGRPAEELA--GVQVASQG 460
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
T H + DH C A+ V + +AP L + I +
Sbjct: 461 TTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYH 512
Query: 263 TSALELQGNVIYLE--VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT---- 316
+ V +G A +PP W S WG T
Sbjct: 513 WGXEHHSSFPAACDPPVHRGW------GAHPKPPLVEGWC------SPGSLWGEPTGIPV 560
Query: 317 -----LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
L++ V D G YTC A N G ++ + L V PP + N+ VLE
Sbjct: 561 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEPGPVNKAVLE 617
Query: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQ 427
N S+ L C+ PP +SW + Q V G + D VL + Q
Sbjct: 618 N------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQ 665
Query: 428 MEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ G + C A + GS + L V+
Sbjct: 666 LSDAGSYRCVASNVAGSTELRYGLRVN 692
Score = 54.7 bits (130), Expect = 2e-07
Identities = 52/183 (28%), Positives = 70/183 (38%), Gaps = 32/183 (17%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA-----GDSGRYTCRAENR 339
L C A PP +SW + +SS W T+ ++ R +R D+G Y C A N
Sbjct: 623 LECLASGVPPPDVSWFKGHQPVSS---WMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNV 679
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
GS + L V PP R L G PVL +RL C +P
Sbjct: 680 AGSTELRYGLRVNVPP-----------RITLPPSLPG---PVLVNTPVRLTCNATGAPSP 725
Query: 400 RLSWTRWGQTVGPSQPSDPG--------VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
L W + G V P+ PG VL L + G ++C A +G + L
Sbjct: 726 TLMWLKDGNPVSPA--GTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVL 783
Query: 452 SVH 454
VH
Sbjct: 784 QVH 786
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 16/175 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLS--SSHPWGPRTLGLELRGVRAGDSGRY 332
++V GQ L+C P L+W R L+ +H P + L++ +G Y
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N +G + + LSV P L A+ V + N S L+C
Sbjct: 1233 SCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS----------LICE 1282
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD--PGV--LELPPIQMEHEGEFTCHAQHPLG 443
+ P ++W + G S+ PG L++ Q E G++TC + LG
Sbjct: 1283 ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1337
Score = 53.5 bits (127), Expect = 5e-07
Identities = 79/309 (25%), Positives = 120/309 (38%), Gaps = 52/309 (16%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V++P T+ Q + + C PAP+ SW+ GA L R + S L
Sbjct: 2571 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 2630
Query: 214 SFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVI 273
+ H TC S GV A + V L V +P ++ +V+
Sbjct: 2631 EIGQALPIHAGRYTCSARNSA-GV-AHKHVFLTVQASP-------------VVKPLPSVV 2675
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-GLELRGVRAG--DSG 330
++ L C A P T++W Q L+ + + L G +LR A D+G
Sbjct: 2676 RAVAEEEVLLP--CEASGIPRPTITW--QKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2731
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 2732 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 2776
Query: 391 CVTHSSPPARLSWTRWGQTVGPS------QPSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
C SP ++W + GQ V + QPS G L + ++ + G +TC A++ +G
Sbjct: 2777 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 2834
Query: 445 QHVSLSLSV 453
+ L++
Sbjct: 2835 ARRRVHLTI 2843
Score = 53.1 bits (126), Expect = 7e-07
Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENR 339
G L L CAA P + W + DR ++ L+ V DSG Y C AENR
Sbjct: 2861 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 2920
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
+G Q + V+ P V+ +A ++E +G S++L CV P
Sbjct: 2921 VGRTQAVSFVHVKEAP----VLQGEAFSYLVEPVGG----------SIQLDCVVRGDPVP 2966
Query: 400 RLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
+ W + G + S G L + + + G + C A++ +G
Sbjct: 2967 DIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMG 3013
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/188 (26%), Positives = 70/188 (37%), Gaps = 22/188 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSS-----HPWGPRTLGLELRGVRAGDS 329
L V++G RL C P +SW + L H L L L +
Sbjct: 890 LTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 948
Query: 330 GRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRL 389
G YTC N +G+ Q L L V PP+ + T + V++ L
Sbjct: 949 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 996
Query: 390 VCVTHSSPPARLSWTRWGQTVGPS---QPSDPG-VLELPPIQMEHEGEFTCHAQHPLGSQ 445
C PP ++W R GQ VG Q + G L + Q H G ++C A++ G
Sbjct: 997 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1056
Query: 446 HVSLSLSV 453
LSV
Sbjct: 1057 ERKFELSV 1064
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/216 (26%), Positives = 80/216 (37%), Gaps = 22/216 (10%)
Query: 268 LQGNVI-YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVR 325
LQG YL G ++L C P + W+ L SH G L +R
Sbjct: 2938 LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTE 2997
Query: 326 AGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 385
D+GRY C AEN +G ++ + L +Q P V Q + V G
Sbjct: 2998 RDDAGRYQCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGD 3042
Query: 386 SLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPL 442
+ L C P + W + GQ + S + G L L ++ G + C A + L
Sbjct: 3043 DVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLL 3102
Query: 443 GSQHVSLSLSVHWKLEHGGGLGLGAALGA--GVAAL 476
GS L V + + G G G GVA L
Sbjct: 3103 GSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATL 3138
Score = 51.6 bits (122), Expect = 2e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 23/175 (13%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSG 330
L +G L C A P ++W + +S + G T+ L ++ + D+G
Sbjct: 2765 LSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE--GKFTIQPSGELLVKNLEGQDAG 2822
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
YTC AEN +G ++ + L++ P V L SL + G L L
Sbjct: 2823 TYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL--GDRLWLR 2867
Query: 391 CVTHSSPPARLSWTRWGQ--TVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
C SP R+ WT + T G S+ L+ + E G + C A++ +G
Sbjct: 2868 CAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922
Score = 50.4 bits (119), Expect = 5e-06
Identities = 53/194 (27%), Positives = 75/194 (38%), Gaps = 35/194 (18%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL--------GLELRGVRA 326
+ V Q L C AD P +SW +DRV P PR+ L ++ V A
Sbjct: 2400 VNVSVNQTALLPCQADGVPAPLVSW-RKDRV-----PLDPRSPRFEILPEGSLRIQPVLA 2453
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+G Y C A N GS +Q DL V PP + S +N T+ + P L
Sbjct: 2454 QDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TPAL---- 2500
Query: 387 LRLVCVTHSSPPARLSWTRWGQTV------GPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
L C SP + W + GQ + G + L L + +F C +
Sbjct: 2501 --LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2558
Query: 441 PLGSQHVSLSLSVH 454
+G H ++VH
Sbjct: 2559 EVGEAHRLYQVTVH 2572
Score = 49.3 bits (116), Expect = 1e-05
Identities = 65/294 (22%), Positives = 111/294 (37%), Gaps = 45/294 (15%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTD 225
+L PG P+ ++C + P P+ +W + R ++ VL D
Sbjct: 2224 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVLRV------RDAG 2273
Query: 226 LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRL 285
L + S G + +++ R+RV P + + +G + + GQ + L
Sbjct: 2274 LYTCLAESPAG-AIEKSFRVRVQAPP------------NIVGPRGPRFVVGLAPGQLV-L 2319
Query: 286 LCAADSQPPATLSWVLQDRVLSS-SHPWGP-RTLGLELRGVRAGDSGRYTCRAENRLGSQ 343
C+ +++P ++W VL +H P R L+L+ + DSG Y+C A N GS
Sbjct: 2320 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 2379
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
A + + P +R N +V Q+ L C P +SW
Sbjct: 2380 SVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLVSW 2424
Query: 404 TRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+ + P P G L + P+ + G + C A + GS L V
Sbjct: 2425 RKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 2478
Score = 46.6 bits (109), Expect = 7e-05
Identities = 71/320 (22%), Positives = 110/320 (34%), Gaps = 55/320 (17%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWTG--AALSPRRTRP 205
T++ + +++ T+ G P + V A C PAP SW L PR R
Sbjct: 2379 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2438
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRL----RVAYAPKDLIISISHD 261
L P C S R +R+ +A +P +L ++
Sbjct: 2439 EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA--- 2495
Query: 262 NTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL---- 317
+T AL L C A P + W + L G L
Sbjct: 2496 HTPAL------------------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2537
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGT 377
L L DS ++ C N +G + ++V PP + Q + TV
Sbjct: 2538 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT---IADDQTDFTVT------M 2588
Query: 378 SLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGE 433
PV+ L C + P +SW++ G +G + S G LE+ H G
Sbjct: 2589 MAPVV------LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGR 2642
Query: 434 FTCHAQHPLGSQHVSLSLSV 453
+TC A++ G H + L+V
Sbjct: 2643 YTCSARNSAGVAHKHVFLTV 2662
Score = 46.2 bits (108), Expect = 9e-05
Identities = 43/170 (25%), Positives = 66/170 (38%), Gaps = 20/170 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTC 334
V+ G L C D+ P T++W + L + G LE++ + D G Y+C
Sbjct: 1762 VRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSC 1821
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
+ N G + L+VQ PP EN T + + G L L C
Sbjct: 1822 KVSNVAGEAVRTFTLTVQVPP-------------TFENPKTET-VSQVAGSPLVLTCDVS 1867
Query: 395 SSPPARLSWTRWGQTVGPSQ----PSDPGVLELPPIQMEHEGEFTCHAQH 440
P ++W + V S S G L+L +Q G +TC A++
Sbjct: 1868 GVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 26/185 (14%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG------LELRGVRAGDSGRYT 333
G + L C P + W +DR P GP L + G GD GRY
Sbjct: 141 GADVELQCWTSGVPTPQVEWT-KDR--QPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQ 197
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A + G Q + L V PP + +N T + V+E ++L+C
Sbjct: 198 CVAFSPAGQQARDFQLRVHAPP-----TIWGSNET--------GEVAVMEDHLVQLLCEA 244
Query: 394 HSSPPARLSWTRWGQTVGPS----QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
P ++W + G + S L+L Q G +TC A + +G+ +
Sbjct: 245 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 304
Query: 450 SLSVH 454
L V+
Sbjct: 305 RLDVY 309
Score = 33.1 bits (74), Expect = 0.75
Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 22/114 (19%)
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTR-------------------WGQTVGPSQ 414
G ++ + GQSL L C + P + W + WGQ G
Sbjct: 23 GRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 82
Query: 415 PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLEHGGGLGLGAA 468
+ L P IQ G ++C A++ G+ L V L LG GAA
Sbjct: 83 LDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLV---LTPPSVLGAGAA 133
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 75.1 bits (183), Expect = 2e-13
Identities = 79/358 (22%), Positives = 131/358 (36%), Gaps = 59/358 (16%)
Query: 116 LVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTV 175
L IR ++ DE Y +R +F + V + + T GQ VT+
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTL 233
Query: 176 ICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHF-----SVLSFTPSPQDHDTDLTCHV 230
+C + P P+ SWT + + S L+ ++ + + C
Sbjct: 234 VC----DAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIA 289
Query: 231 DFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAAD 290
+ K T+ L+V PK + +N +A+EL+ V L C A
Sbjct: 290 E--NKAGEQDATIHLKVFAKPKITYV----ENQTAMELEEQVT-----------LTCEAS 332
Query: 291 SQPPATLSWVLQDRVLSSSHPW---------GPRTLGLELRGVRAGDSGRYTCRAENRLG 341
P +++W R +SS R L L+ ++ D+G Y C A N +G
Sbjct: 333 GDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 392
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
Q++ L VQY P+ L ++ EG + + C + P A +
Sbjct: 393 QDSQSMYLEVQYAPK----------------LQGPVAVYTWEGNQVNITCEVFAYPSATI 436
Query: 402 SWTRWGQTVGPSQPSD--------PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
SW R GQ + S S+ LE+ P G + C A + +G + + L
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/220 (22%), Positives = 87/220 (39%), Gaps = 33/220 (15%)
Query: 252 KDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV-----LQDRVL 306
KD+ + ++ T ++ + N++ GQ + L+C A+ P T+SW ++
Sbjct: 202 KDIQVIVNVPPT--IQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED 259
Query: 307 SSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQAN 366
+ + + L ++ V D Y C AEN+ G Q + L V P+ V N
Sbjct: 260 DEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYV----EN 315
Query: 367 RTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPG------- 419
+T +E LE Q + L C P ++W + + + + G
Sbjct: 316 QTAME----------LEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSH 364
Query: 420 ----VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHW 455
L L IQ GE+ C A + +G S+ L V +
Sbjct: 365 ARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQY 404
Score = 53.5 bits (127), Expect = 5e-07
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 41/201 (20%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDR-----------VLSSSHPWGPRTLGLELRGV 324
E ++G+ ++C S P T+ W + R VLS+++ L++RG+
Sbjct: 128 EFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY--------LQIRGI 179
Query: 325 RAGDSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ D G Y C + D+ V PP QA + ++ N
Sbjct: 180 KKTDEGTYRCEGRILARGEINFKDIQVIVNVPP------TIQARQNIVNATAN------- 226
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPS-------DPGVLELPPIQMEHEGEFT 435
GQS+ LVC P +SWT+ G+ + + D L + + E E+
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 436 CHAQHPLGSQHVSLSLSVHWK 456
C A++ G Q ++ L V K
Sbjct: 287 CIAENKAGEQDATIHLKVFAK 307
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 75.1 bits (183), Expect = 2e-13
Identities = 79/358 (22%), Positives = 131/358 (36%), Gaps = 59/358 (16%)
Query: 116 LVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTV 175
L IR ++ DE Y +R +F + V + + T GQ VT+
Sbjct: 174 LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTL 233
Query: 176 ICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHF-----SVLSFTPSPQDHDTDLTCHV 230
+C + P P+ SWT + + S L+ ++ + + C
Sbjct: 234 VC----DAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIA 289
Query: 231 DFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAAD 290
+ K T+ L+V PK + +N +A+EL+ V L C A
Sbjct: 290 E--NKAGEQDATIHLKVFAKPKITYV----ENQTAMELEEQVT-----------LTCEAS 332
Query: 291 SQPPATLSWVLQDRVLSSSHPW---------GPRTLGLELRGVRAGDSGRYTCRAENRLG 341
P +++W R +SS R L L+ ++ D+G Y C A N +G
Sbjct: 333 GDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 392
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
Q++ L VQY P+ L ++ EG + + C + P A +
Sbjct: 393 QDSQSMYLEVQYAPK----------------LQGPVAVYTWEGNQVNITCEVFAYPSATI 436
Query: 402 SWTRWGQTVGPSQPSD--------PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
SW R GQ + S S+ LE+ P G + C A + +G + + L
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/220 (22%), Positives = 87/220 (39%), Gaps = 33/220 (15%)
Query: 252 KDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWV-----LQDRVL 306
KD+ + ++ T ++ + N++ GQ + L+C A+ P T+SW ++
Sbjct: 202 KDIQVIVNVPPT--IQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED 259
Query: 307 SSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQAN 366
+ + + L ++ V D Y C AEN+ G Q + L V P+ V N
Sbjct: 260 DEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYV----EN 315
Query: 367 RTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPG------- 419
+T +E LE Q + L C P ++W + + + + G
Sbjct: 316 QTAME----------LEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSH 364
Query: 420 ----VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHW 455
L L IQ GE+ C A + +G S+ L V +
Sbjct: 365 ARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQY 404
Score = 53.5 bits (127), Expect = 5e-07
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 41/201 (20%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDR-----------VLSSSHPWGPRTLGLELRGV 324
E ++G+ ++C S P T+ W + R VLS+++ L++RG+
Sbjct: 128 EFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY--------LQIRGI 179
Query: 325 RAGDSGRYTCRAENRLGSQQQALDLSV--QYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ D G Y C + D+ V PP QA + ++ N
Sbjct: 180 KKTDEGTYRCEGRILARGEINFKDIQVIVNVPP------TIQARQNIVNATAN------- 226
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPS-------DPGVLELPPIQMEHEGEFT 435
GQS+ LVC P +SWT+ G+ + + D L + + E E+
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 436 CHAQHPLGSQHVSLSLSVHWK 456
C A++ G Q ++ L V K
Sbjct: 287 CIAENKAGEQDATIHLKVFAK 307
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 74.7 bits (182), Expect = 2e-13
Identities = 81/352 (23%), Positives = 138/352 (39%), Gaps = 56/352 (15%)
Query: 116 LVIRDAQREDEAWY------FFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPE-TLE 168
L IR+ Q D Y F +++G+ H S V + ++ P+ T++
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVS------IHPPQLTVQ 1878
Query: 169 PGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTS--HFSVLSFTPSPQDHDTDL 226
PGQ + F + P P+ WTG P P+ + H +L
Sbjct: 1879 PGQ----LAEFRCSATGSPTPTLEWTGG---PGGQLPAKAQIHGGILRLPAVEPTDQAQY 1931
Query: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
C S A+ + + P+ + +S + T +V G+ +RL
Sbjct: 1932 LCRAHSSAGQQVARAVLHVHGGGGPR---VQVSPERT------------QVHAGRTVRLY 1976
Query: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRT-----LGLELRGVRAGDSGRYTCRAENRLG 341
C A P AT++W R S P R+ L + + D+G Y C A + G
Sbjct: 1977 CRAAGVPSATITW----RKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAG 2032
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
+ Q + + V++S ++ + +S V EGQ+L L CV S A++
Sbjct: 2033 TAQARIQV----------VVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQV 2082
Query: 402 SWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+W R G ++ P L LP + GE+ C ++ G + S+++SV
Sbjct: 2083 TWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSV 2134
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/186 (30%), Positives = 75/186 (40%), Gaps = 15/186 (8%)
Query: 274 YLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGR 331
+ VQ G+ ++L C A PP T W RV SS P L RA DSGR
Sbjct: 3307 HASVQAGETVQLQCLAHGTPPLTFQW---SRV-GSSLPGRATARNELLHFERAAPEDSGR 3362
Query: 332 YTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE----GQSL 387
Y CR N++GS + L VQ PP +L A T + P LE G S+
Sbjct: 3363 YRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQV-----TPQLETKSIGASV 3417
Query: 388 RLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHV 447
C S +L W + G + P GVL + + +G + C A P G
Sbjct: 3418 EFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477
Query: 448 SLSLSV 453
S L +
Sbjct: 3478 SAQLVI 3483
Score = 70.5 bits (171), Expect = 4e-12
Identities = 55/200 (27%), Positives = 88/200 (44%), Gaps = 12/200 (6%)
Query: 256 ISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPR 315
+S SH A ++ + G L L C SQ P T++W + L S H +
Sbjct: 2524 LSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRH----Q 2579
Query: 316 TLGLELR--GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENL 373
+G LR V DSG Y C N GS++ +L +++Q + VS R
Sbjct: 2580 IVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI----- 2634
Query: 374 GNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGE 433
+S V+EGQ+L L CV P A ++W + G ++ + L L + + GE
Sbjct: 2635 -ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGE 2693
Query: 434 FTCHAQHPLGSQHVSLSLSV 453
+ C A + + + S+ +SV
Sbjct: 2694 YVCRANNNIDALEASIVISV 2713
Score = 69.7 bits (169), Expect = 7e-12
Identities = 73/298 (24%), Positives = 117/298 (39%), Gaps = 44/298 (14%)
Query: 164 PETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPST-----SHFSVLSFTPS 218
P ++ G+ VT+ CV P S WT + +P + T SH + +
Sbjct: 3121 PVWVKVGKAVTLECVSAGE----PRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAK 3176
Query: 219 PQDHDTDLTCHVDFSRKGV-SAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEV 277
P D T +V ++ + +AQ+ V ++I+ A ++Q L V
Sbjct: 3177 PSDAGT----YVCLAQNALGTAQKQV---------EVIVDTGAMAPGAPQVQAEEAELTV 3223
Query: 278 QKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCR 335
+ G L C+A P T+ W L S PW R G L + V DSG+Y C
Sbjct: 3224 EAGHTATLRCSATGSPAPTIHW----SKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICN 3279
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
A + G + + L V+ PP TV E+ V G++++L C+ H
Sbjct: 3280 ATSPAGHAEATIILHVESPPYAT---------TVPEHAS------VQAGETVQLQCLAHG 3324
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+PP W+R G ++ + +L E G + C + +GS L V
Sbjct: 3325 TPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLV 3382
Score = 60.8 bits (146), Expect = 3e-09
Identities = 63/261 (24%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 200 PRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISIS 259
P R + S + TP+ + CHV G ++ T LI++I
Sbjct: 2575 PSRHQIVGSRLRIPQVTPADSG---EYVCHVS---NGAGSRET----------SLIVTIQ 2618
Query: 260 HDNTSALELQGNVIYLE-----VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP 314
+S + I +E V +GQ L L C QP A ++W + L S H
Sbjct: 2619 GSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRH---- 2674
Query: 315 RTLG--LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLEN 372
+T G L L + DSG Y CRA N + + + ++ +SV P + +E+
Sbjct: 2675 QTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVS-PSAGSPSAPGSSMPIRIES 2733
Query: 373 LGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEG 432
+S V EG++L L CV A+++W + G ++ + L L + G
Sbjct: 2734 ----SSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSG 2789
Query: 433 EFTCHAQHPLGSQHVSLSLSV 453
E+ C G S+ +++
Sbjct: 2790 EYVCRVMGSSGPLEASVLVTI 2810
Score = 56.6 bits (135), Expect = 6e-08
Identities = 51/210 (24%), Positives = 85/210 (40%), Gaps = 26/210 (12%)
Query: 256 ISISHDNTSALELQGNVIYLE-----VQKGQFLRLLCAA-DSQPPATLSWVLQDRVLSSS 309
+++ S+ L+ VI ++ VQ+GQ C D P +L W +++ L +
Sbjct: 3007 VTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDN 3066
Query: 310 HPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTV 369
P + + G R + G Y C A N G Q ++LSV PP
Sbjct: 3067 VHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPP-------------T 3113
Query: 370 LENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPG------VLEL 423
+ L G + V G+++ L CV+ P + WTR T + G VL++
Sbjct: 3114 VSVLPEG-PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQI 3172
Query: 424 PPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+ G + C AQ+ LG+ + + V
Sbjct: 3173 SSAKPSDAGTYVCLAQNALGTAQKQVEVIV 3202
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/178 (25%), Positives = 75/178 (42%), Gaps = 5/178 (2%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSS-SHPWGPRTLGLELRGVRAGDSGRYTCR 335
V +GQ L L C A ++W + L + G R L L V DSG Y CR
Sbjct: 2062 VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR---LRLPQVSPADSGEYVCR 2118
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
EN G ++ ++ +SV + + T + +S V EGQ+L L CV
Sbjct: 2119 VENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSS-HVAEGQTLDLNCVVPG 2177
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
A+++W + G ++ + +L L + GE+ CH G S+ +++
Sbjct: 2178 QAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/191 (27%), Positives = 71/191 (37%), Gaps = 24/191 (12%)
Query: 277 VQKGQFLRLLCAADSQPPA-TLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYT 333
V+ G + +C A S+ PA TL W R+ + P L +R V+ D+G Y
Sbjct: 1783 VRPGADVTFICTAKSKSPAYTLVWT---RLHNGKLPTRAMDFNGILTIRNVQLSDAGTYV 1839
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C N Q L VQ +VS + L V GQ C
Sbjct: 1840 CTGSNMFAMDQGTATLHVQASGTLSAPVVSI----------HPPQLTVQPGQLAEFRCSA 1889
Query: 394 HSSPPARLSWTRW--GQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
SP L WT GQ +Q G+L LP ++ + ++ C A G Q L
Sbjct: 1890 TGSPTPTLEWTGGPGGQLPAKAQIHG-GILRLPAVEPTDQAQYLCRAHSSAGQQVARAVL 1948
Query: 452 SVHWKLEHGGG 462
V HGGG
Sbjct: 1949 HV-----HGGG 1954
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/179 (25%), Positives = 76/179 (42%), Gaps = 9/179 (5%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP-WGPRTLGLELRGVRAGDSGRYTCR 335
V +GQ L L C Q A ++W + L + H GP L L V DSG Y+C+
Sbjct: 2838 VAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPL---LRLNQVSPADSGEYSCQ 2894
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
G+ + ++ ++++ A +E +S V EGQ+L L CV
Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIE----ASSSHVTEGQTLDLNCVVPG 2950
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCH-AQHPLGSQHVSLSLSV 453
A+++W + G ++ + L L + GE+ C A P Q S +++V
Sbjct: 2951 QAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTV 3009
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/177 (23%), Positives = 73/177 (41%), Gaps = 4/177 (2%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V +G+ L L C Q A ++W + L S H R L L V DSG Y CR
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQ--TRGSRLRLHHVSPADSGEYVCRV 2795
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
G + ++ ++++ + + + + +S V EGQ+L L CV
Sbjct: 2796 MGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRI--EPSSSRVAEGQTLDLKCVVPGQ 2853
Query: 397 PPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
A+++W + G + +L L + GE++C G+ S+ +++
Sbjct: 2854 AHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTI 2910
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/294 (21%), Positives = 118/294 (40%), Gaps = 34/294 (11%)
Query: 163 IPE--TLEPGQPVTVICVFNWAFKKCPAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPS 218
+PE +++ G+ V + C+ + P +F W+ G++L R +T+ +L F +
Sbjct: 3304 VPEHASVQAGETVQLQCLAHGT----PPLTFQWSRVGSSLPGR----ATARNELLHFERA 3355
Query: 219 PQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDL-IISISHDNTSALELQGNVIYLEV 277
+ C V + K SA+ +L V P L SI +T +++ + +
Sbjct: 3356 APEDSGRYRCRV--TNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSI 3413
Query: 278 QKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAE 337
G + CA S L W + L H L ++ + G Y C+A
Sbjct: 3414 --GASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVL--RIQNLDQSCQGTYICQAH 3469
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
G Q + L +Q P +VL N+ V+ G ++ C+ P
Sbjct: 3470 GPWGKAQASAQLVIQALP------------SVLINIRTSVQTVVV-GHAVEFECLALGDP 3516
Query: 398 PARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGS--QHVSL 449
+++W++ G + P GV+ + +++ G++ C A + G+ HV L
Sbjct: 3517 KPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLL 3570
Score = 50.1 bits (118), Expect = 6e-06
Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 28/212 (13%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGRYT 333
+V +GQ L L C Q A ++W + L H +T G LR +A DSG Y
Sbjct: 2351 QVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRH----QTHGSLLRLYQASPADSGEYV 2406
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLG-------NGTSLPVLEGQS 386
CR LGS P V+V+ + LG +S V EGQ+
Sbjct: 2407 CRV---LGSSV----------PLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT 2453
Query: 387 LRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
L L C+ A+++W + G ++ L L + GE+ C G+Q
Sbjct: 2454 LDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQE 2513
Query: 447 VSLSLSVHWKL--EHGGGLGLGAALGAGVAAL 476
S+ +++ +L H G+ + + A+L
Sbjct: 2514 ASVLVTIQQRLSGSHSQGVAYPVRIESSSASL 2545
Score = 49.3 bits (116), Expect = 1e-05
Identities = 50/187 (26%), Positives = 74/187 (39%), Gaps = 12/187 (6%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V +GQ L L C Q A ++W + L + H R L + D+G+Y CRA
Sbjct: 2256 VAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ--VRGSRLYIFQASPADAGQYVCRA 2313
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
N + + Q NL +E +S V EGQ+L L CV
Sbjct: 2314 SNGMEASITVTVTGTQ--GANLAYPAGSTQPIRIEP----SSSQVAEGQTLDLNCVVPGQ 2367
Query: 397 PPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWK 456
A+++W + G ++ + +L L GE+ C LGS V L SV
Sbjct: 2368 SHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRV---LGSS-VPLEASVLVT 2423
Query: 457 LEHGGGL 463
+E G +
Sbjct: 2424 IEPAGSV 2430
Score = 43.9 bits (102), Expect = 4e-04
Identities = 48/217 (22%), Positives = 86/217 (39%), Gaps = 27/217 (12%)
Query: 238 SAQRTVRLRVAYAPKDLIISIS-----HDNTSALELQGNVIYLEVQ-------KGQFLRL 285
S + R+ PK+ I++S H S + G+ + ++ +GQ L L
Sbjct: 2112 SGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDL 2171
Query: 286 LCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRYTCRAENRLGSQ 343
C Q A ++W + L + H +T G L L V DSG Y C G
Sbjct: 2172 NCVVPGQAHAQVTWHKRGGSLPARH----QTHGSLLRLHQVTPADSGEYVCHVVGTSGPL 2227
Query: 344 QQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSW 403
+ ++ ++++ V+ +E+ +S V EGQ+L L CV A+++W
Sbjct: 2228 EASVLVTIE-----ASVIPGPIPPVRIES----SSSTVAEGQTLDLSCVVAGQAHAQVTW 2278
Query: 404 TRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQH 440
+ G ++ L + G++ C A +
Sbjct: 2279 YKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASN 2315
Score = 43.1 bits (100), Expect = 7e-04
Identities = 42/180 (23%), Positives = 63/180 (35%), Gaps = 13/180 (7%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQD-RVLSSSHPWGPRTLGLELRGVRAGDSGRYTCR 335
V +G L C PP W +D R + S + L V+ D+G Y C
Sbjct: 1688 VPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICT 1747
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
N S +L V P + + R S V G + +C S
Sbjct: 1748 CRNLHQSNTSRAELLVTEAPSKPITVTVEEQR----------SQSVRPGADVTFICTAKS 1797
Query: 396 SPPA-RLSWTRWGQTVGPSQPSD-PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
PA L WTR P++ D G+L + +Q+ G + C + + +L V
Sbjct: 1798 KSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHV 1857
Score = 43.1 bits (100), Expect = 7e-04
Identities = 39/175 (22%), Positives = 68/175 (38%), Gaps = 20/175 (11%)
Query: 280 GQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGL-ELRGVRAGDSGRYTCRAEN 338
G + C A P ++W +V P ++ G+ + V D+G+Y C A N
Sbjct: 3503 GHAVEFECLALGDPKPQVTW---SKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATN 3559
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
G+ Q + L VQ P+ + + Q R V G + C+ P
Sbjct: 3560 AAGTTQSHVLLLVQALPQ---ISMPQEVR-------------VPAGSAAVFPCIASGYPT 3603
Query: 399 ARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+SW++ ++ P + +L LP ++ + G + C A + G L V
Sbjct: 3604 PDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 31.6 bits (70), Expect = 2.2
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-----LELRGVRAGDS 329
++ +GQ + C A P ++W L + S HP T L +R V+ D
Sbjct: 416 IQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPS-HPRVTVTSEGGRGTLIIRDVKESDQ 474
Query: 330 GRYTCRAENRLG 341
G YTC A N G
Sbjct: 475 GAYTCEAMNARG 486
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 74.3 bits (181), Expect = 3e-13
Identities = 53/188 (28%), Positives = 89/188 (47%), Gaps = 15/188 (7%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRY 332
++++ L L C A + P A+LSW + L S G L+++ + D+GRY
Sbjct: 2684 VKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRY 2743
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC A N G + D+++Q PP ++ +L+ NG + V+ + L C
Sbjct: 2744 TCVASNIAGEDELDFDVNIQVPPSFQKLW---EIGNMLDTGRNGEAKDVIINNPISLYCE 2800
Query: 393 THSSPPARLSWTRWGQTVGPSQPSD-----PG--VLELPPIQMEHEGEFTCHAQHPLGSQ 445
T+++PP L+W + G P SD PG VL++P ++E G +TC A + G
Sbjct: 2801 TNAAPPPTLTWYKDGH---PLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857
Query: 446 HVSLSLSV 453
+ + V
Sbjct: 2858 SLQYDVRV 2865
Score = 71.6 bits (174), Expect = 2e-12
Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 25/188 (13%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRYTCRAEN 338
+RL C A P +L+W L+D SS G + L L L + D+GRYTC A N
Sbjct: 2029 VRLECEARGIPAPSLTW-LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
G +Q+ +DL V PP +G ++ VL Q++ L+C + + PP
Sbjct: 2088 AAGEKQRDIDLRVYVPP---------------NIMGEEQNVSVLISQAVELLCQSDAIPP 2132
Query: 399 ARLSWTRWGQTV----GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
L+W + G + G S + VL++ Q++ G +TC A + G + ++++
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI- 2191
Query: 455 WKLEHGGG 462
W + GG
Sbjct: 2192 WVPPNIGG 2199
Score = 67.0 bits (162), Expect = 5e-11
Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 22/185 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRY 332
V +G+ + L C PP T++W+ L + G L L+L+ + D+GRY
Sbjct: 2304 VTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAK--GVEILDEGHILQLKNIHVSDTGRY 2361
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
C A N G + DLSV PP +++ N + ++ V+E S+ L C
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP------------SIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P ++W + G V S S +L L ME G++TC ++ G +
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query: 449 LSLSV 453
LSV
Sbjct: 2470 FGLSV 2474
Score = 67.0 bits (162), Expect = 5e-11
Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 20/177 (11%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAENRLG 341
+ L C AD PP ++W R + S + G L++ V+ GD+G YTC A N G
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAG 4155
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
S + L+V PP R+ ++ + TV EN Q++ L CV P +
Sbjct: 4156 SSSTSTKLTVHVPP---RIRSTEGHYTVNEN-----------SQAI-LPCVADGIPTPAI 4200
Query: 402 SWTR----WGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+W + +G G L L + +E G +TC A + G ++SL+VH
Sbjct: 4201 NWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVH 4257
Score = 66.6 bits (161), Expect = 6e-11
Identities = 74/302 (24%), Positives = 120/302 (39%), Gaps = 43/302 (14%)
Query: 163 IPETLEPGQPVTVICVFNWAFKKCPAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPSPQ 220
I T+E G PVT+ C + P PS W+ G +S + S L
Sbjct: 989 ILSTIE-GIPVTLPCKASGN----PKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG 1043
Query: 221 DHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKG 280
+ + C + A+R V+L V P+ + D Q + + V G
Sbjct: 1044 EESGEYVCTA--TNTAGYAKRKVQLTVYVRPR-----VFGDQRGLS--QDKPVEISVLAG 1094
Query: 281 QFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-----GLELRGVRAGDSGRYTCR 335
+ + L C S PP ++W + +++S P+ PR +++ R DSG Y C
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLIS---PFSPRHTFLPSGSMKITETRTSDSGMYLCV 1151
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
A N G+ QA+ L+V PP+ R L V GQ + + C
Sbjct: 1152 ATNIAGNVTQAVKLNVHVPPKIQR---------------GPKHLKVQVGQRVDIPCNAQG 1196
Query: 396 SPPARLSWTRWGQTV---GPSQPSDP-GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
+P ++W++ G T+ G S+P G L + G +TC A + G+ ++L
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 452 SV 453
V
Sbjct: 1257 HV 1258
Score = 65.9 bits (159), Expect = 1e-10
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 17/178 (9%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWG--PRTLGLELRGVRAGDSGRYTCRAENRL 340
+ L C ++ PP TL+W L+SS P L++ + D+GRYTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G D+ V PP ++ AN + E + VL +S + C++ SP R
Sbjct: 2855 GEDSLQYDVRVLVPP-----IIKGANSDLPE------EVTVLVNKSALIECLSSGSPAPR 2903
Query: 401 LSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
SW + GQ + S+ +L++ Q+ G + C A++ GS +L+VH
Sbjct: 2904 NSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH 2961
Score = 64.3 bits (155), Expect = 3e-10
Identities = 68/276 (24%), Positives = 105/276 (38%), Gaps = 56/276 (20%)
Query: 153 TALTKKPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRP 205
T L V++ ++ + + V N +C PAPS +W G+ +S
Sbjct: 2000 TELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGL 2059
Query: 206 STSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSA 265
+ S Q DT V + G QR + LRV Y P +++
Sbjct: 2060 QVLSGGRILALTSAQISDTGRYTCVAVNAAG-EKQRDIDLRV-YVPPNIM---------- 2107
Query: 266 LELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPW--------GPRTL 317
G + V Q + LLC +D+ PP TL+W L HP
Sbjct: 2108 ----GEEQNVSVLISQAVELLCQSDAIPPPTLTW------LKDGHPLLKKPGLSISENRS 2157
Query: 318 GLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNG- 376
L++ + D+GRYTC A N G ++ ++++ PP N+G
Sbjct: 2158 VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP----------------NIGGSD 2201
Query: 377 --TSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV 410
T L V+EG + L+C + PP L W + G V
Sbjct: 2202 ELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPV 2237
Score = 62.8 bits (151), Expect = 9e-10
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 23/180 (12%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRYTCRAENRL 340
L C A PP T++W+ + + +S R L L++ + DSG YTC A N
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G Q+ LS+Q PP S A + + + VL G+++ LVC + P
Sbjct: 3231 GKAQKYYFLSIQVPP-------SVAGAEI------PSDVSVLLGENVELVCNANGIPTPL 3277
Query: 401 LSWTRWGQTVGPSQ------PSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ W + G+ + + ++ L + G++TC A +P G + +L+V+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337
Score = 62.8 bits (151), Expect = 9e-10
Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 21/177 (11%)
Query: 283 LRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA--GDSGRYTCRAENRL 340
+ + C A PP ++W+ L S G +R VRA D YTC A NR
Sbjct: 3360 INIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRA 3419
Query: 341 GSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPAR 400
G + +L V PP ++N + VL+G S + C+T +P
Sbjct: 3420 GVDNKHYNLQVFAPPN-------------MDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 401 LSWTRWGQTVG----PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG--SQHVSLSL 451
++W R GQ +G + + VL+L + E G++TC A + G S+H L +
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 62.8 bits (151), Expect = 9e-10
Identities = 68/284 (23%), Positives = 107/284 (37%), Gaps = 52/284 (18%)
Query: 187 PAPSFSWTGAALSPRRTRPSTSHFSVLSFTP-----SPQDHDTDLTCHVDFSRKGVSAQR 241
P P +W L P +SH +L+ Q D + V +R GV +
Sbjct: 3370 PPPQINWLKNGLP----LPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVD-NK 3424
Query: 242 TVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVL 301
L+V +AP ++ DN+ E + V KG + C D P +++W+
Sbjct: 3425 HYNLQV-FAPPNM------DNSMGTE------EITVLKGSSTSMACITDGTPAPSMAWLR 3471
Query: 302 QDRVLSSSHPWGPRTLGLELRGVRAG--DSGRYTCRAENRLGSQQQALDLSVQYPPENLR 359
+ L T G+ L+ ++A DSG+YTC A N G + L V PP
Sbjct: 3472 DGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH--- 3528
Query: 360 VMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWG---------QTV 410
+ + V+ L L C+ P +++W + G QT+
Sbjct: 3529 ----------INGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL 3578
Query: 411 GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
G + VL + Q+E G +TC A P G + VH
Sbjct: 3579 GGGE-----VLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 19/185 (10%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAG--DSGRY 332
+ V + + L C A P +++W +S S+ + G LR ++ D+G+Y
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQY 2455
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC N G +++ LSV PP + LE+ + V E QS+ L C
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIV-------GENTLED------VKVKEKQSVTLTCE 2502
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+P ++W + GQ + + S L++ +Q+ H G +TC A P G + S
Sbjct: 2503 VTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRS 2562
Query: 449 LSLSV 453
SL+V
Sbjct: 2563 FSLNV 2567
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/186 (24%), Positives = 85/186 (45%), Gaps = 17/186 (9%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRV--LSSSHPWGPRTLGLELRGVRAGDSGRY 332
L V F+ L C PP LSW+ ++ L+++ P L++ + D G Y
Sbjct: 2974 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEY 3033
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC A N+ G ++ L+V PP +++ S++ V V EG S+ L C
Sbjct: 3034 TCIAINQAGESKKKFSLTVYVPP-SIKDHDSESLSVV----------NVREGTSVSLECE 3082
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
+++ PP ++W + G+ + S +D +L + ++ G++ C A + G +
Sbjct: 3083 SNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKN 3142
Query: 449 LSLSVH 454
L+V+
Sbjct: 3143 FHLNVY 3148
Score = 58.2 bits (139), Expect = 2e-08
Identities = 88/384 (22%), Positives = 137/384 (35%), Gaps = 54/384 (14%)
Query: 81 KTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVR 140
K G PV+ +N R + R T G + V+R+A E+ +
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFG---------- 2471
Query: 141 HSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW--TGAAL 198
LS + DV + E Q VT+ C P P +W G L
Sbjct: 2472 ---LSVLVPPHIVGENTLEDVKVKEK----QSVTLTCEVTGN----PVPEITWHKDGQPL 2520
Query: 199 SPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISI 258
S L T H TC S R+ L V +P I +
Sbjct: 2521 QEDEAHHIISGGRFLQITNVQVPHTGRYTCLA--SSPAGHKSRSFSLNVFVSPT--IAGV 2576
Query: 259 SHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPW----GP 314
D GN + V L+C A S PPAT++W L S+ G
Sbjct: 2577 GSD--------GNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 315 RTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLG 374
RTL ++ + ++GRY+C A N G + ++ V PP N+ L G
Sbjct: 2629 RTL--QILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP--------IINKGDLWGPG 2678
Query: 375 -NGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQ----PSDPGVLELPPIQME 429
+ + + +L L C ++ P A LSW + GQ + ++ L++ Q+
Sbjct: 2679 LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQIS 2738
Query: 430 HEGEFTCHAQHPLGSQHVSLSLSV 453
G +TC A + G + +++
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNI 2762
Score = 58.2 bits (139), Expect = 2e-08
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 21/186 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRY 332
+ V + + + L C +D+ PP ++W+ L ++ + G L++ GD+ Y
Sbjct: 3631 ITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANY 3690
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
TC A N G + L+V PP N++ G SL +L +S L C+
Sbjct: 3691 TCVASNIAGKTTREFILTVNVPP-NIK--------------GGPQSLVILLNKSTVLECI 3735
Query: 393 THSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P R++W + G + + + G L + + G + C A + G+
Sbjct: 3736 AEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRR 3795
Query: 449 LSLSVH 454
+ L VH
Sbjct: 3796 IDLQVH 3801
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/301 (23%), Positives = 112/301 (37%), Gaps = 54/301 (17%)
Query: 170 GQPVTVICVFNWAFKKCPAPSFSWTG-----AALSPRRTRPSTSHFSVLSFTPSPQDHDT 224
G+ VT+ C K P P +W + SPR T + + S D+
Sbjct: 1094 GEEVTLPC----EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS----DS 1145
Query: 225 DLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLR 284
+ V + G + + V+L V PK +Q +L+VQ GQ +
Sbjct: 1146 GMYLCVATNIAG-NVTQAVKLNVHVPPK---------------IQRGPKHLKVQVGQRVD 1189
Query: 285 LLCAADSQPPATLSW------VLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAEN 338
+ C A P ++W +L D S+P G L + D+G YTC A N
Sbjct: 1190 IPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT----LSIDQATPSDAGIYTCVATN 1245
Query: 339 RLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPP 398
G+ + + L VQ PP + + N T E + N Q + C +P
Sbjct: 1246 IAGTDETEITLHVQEPP-TVEDLEPPYNTTFQERVAN---------QRIEFPCPAKGTPK 1295
Query: 399 ARLSWTRWGQTVGPSQP-----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
+ W G+ + +P D +L + + GE+ C A + G+ +L V
Sbjct: 1296 PTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV 1355
Query: 454 H 454
H
Sbjct: 1356 H 1356
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 17/140 (12%)
Query: 319 LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 378
L L+ R D GRY C N G Q + + L++ PP + N T T
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS-----IKGGNVT--------TD 1556
Query: 379 LPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPS---DPG-VLELPPIQMEHEGEF 434
+ VL ++L C T P ++W + GQ + S + D G L +P Q+ +
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATY 1616
Query: 435 TCHAQHPLGSQHVSLSLSVH 454
TCH + G+ S + V+
Sbjct: 1617 TCHVANVAGTAEKSFHVDVY 1636
Score = 57.8 bits (138), Expect = 3e-08
Identities = 51/195 (26%), Positives = 79/195 (40%), Gaps = 34/195 (17%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSW------VLQD-----RVLSSSHPWGPRTLGLELRG 323
L V +G + LLC + PP L W VL D R+LS G R L + +
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILS-----GGRQLQISI-- 2258
Query: 324 VRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 383
D+ Y+C A N G+ ++ +L V P T+ + + T + V
Sbjct: 2259 AEKSDAALYSCVASNVAGTAKKEYNLQVYIRP------------TITNSGSHPTEIIVTR 2306
Query: 384 GQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQMEHEGEFTCHAQ 439
G+S+ L C PP ++W + G + G + +L+L I + G + C A
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAV 2366
Query: 440 HPLGSQHVSLSLSVH 454
+ G LSVH
Sbjct: 2367 NVAGMTDKKYDLSVH 2381
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 21/197 (10%)
Query: 265 ALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
A+E Y V L L C PP T+ W+ +++ + G L +
Sbjct: 1734 AIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIA 1793
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ ++G Y C A N G ++ +++V PP + S + V V+
Sbjct: 1794 QAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP---TIKSSGLSERV-----------VV 1839
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQ-----PSDPGVLELPPIQMEHEGEFTCH 437
+ + + L C+ + P ++W + Q V +Q S VL++ +E G +TC
Sbjct: 1840 KYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCV 1899
Query: 438 AQHPLGSQHVSLSLSVH 454
A + G + L VH
Sbjct: 1900 ATNAAGETQQHIQLHVH 1916
Score = 54.7 bits (130), Expect = 2e-07
Identities = 71/312 (22%), Positives = 115/312 (36%), Gaps = 53/312 (16%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSWT--GAALSPRRTRPSTSHFSVL 213
V +P ++ G VI + +C P P +W GA L+ R +S+L
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHAR-----YSIL 3763
Query: 214 S--FTPSPQDHDTDLTCHVDFSRKGVSA-QRTVRLRVAYAPKDLIISISHDNTSALELQG 270
F H TD ++ + +R + L+V P SI+ T+
Sbjct: 3764 ENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP-----SIAPGPTNM----- 3813
Query: 271 NVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL----GLELRGVRA 326
+ + VQ L C A P +++W +L+ L L +
Sbjct: 3814 -TVIVNVQT----TLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSV 3868
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
D+ Y C N G ++ +DL+VQ PP S A+ T V +
Sbjct: 3869 DDTATYECTVTNGAGDDKRTVDLTVQVPP-------SIADEP--------TDFLVTKHAP 3913
Query: 387 LRLVCVTHSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPL 442
+ C P + WT+ G + P G +E+ Q+ H G +TC A++
Sbjct: 3914 AVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAA 3973
Query: 443 GSQHVSLSLSVH 454
GS H ++L VH
Sbjct: 3974 GSAHRHVTLHVH 3985
Score = 53.1 bits (126), Expect = 7e-07
Identities = 68/315 (21%), Positives = 118/315 (37%), Gaps = 51/315 (16%)
Query: 160 DVYIPETLE-PGQPVTVICVFNWAFKKC-----PAPSFSWTGAALSPRRTRPSTS----- 208
+VY+P ++E P + V V + N C P P+ +W + +R S S
Sbjct: 3146 NVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK---NHKRIENSDSLEVRI 3202
Query: 209 --HFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSAL 266
S L S + TC S AQ+ L + P + +
Sbjct: 3203 LSGGSKLQIARSQHSDSGNYTCIA--SNMEGKAQKYYFLSIQVPP----------SVAGA 3250
Query: 267 ELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELR 322
E+ +V V G+ + L+C A+ P + W+ + ++S R L +
Sbjct: 3251 EIPSDV---SVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIY 3307
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
G D+G+YTC A N G + + +L+V P T+ N L L
Sbjct: 3308 GALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP------------TIRGNKDEAEKLMTL 3355
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHA 438
S+ + C +PP +++W + G + S + V+ + Q+ +TC A
Sbjct: 3356 VDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVA 3415
Query: 439 QHPLGSQHVSLSLSV 453
+ G + +L V
Sbjct: 3416 SNRAGVDNKHYNLQV 3430
Score = 53.1 bits (126), Expect = 7e-07
Identities = 76/309 (24%), Positives = 120/309 (38%), Gaps = 49/309 (15%)
Query: 161 VYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSW--TGAALSPRRTRPS---TSHF 210
V++P ++ PG + V C P PS +W G L+ + + S S
Sbjct: 3800 VHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSG 3859
Query: 211 SVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQG 270
S++ +PS D T C V + +RTV L V P SI+ + T L
Sbjct: 3860 SLVIISPSVDDTAT-YECTV--TNGAGDDKRTVDLTVQVPP-----SIADEPTDFL---- 3907
Query: 271 NVIYLEVQKGQFLRLLCAADSQPPATLSWVLQD-RVLSSSHPWGPRTLG-LELRGVRAGD 328
V K + C A P ++ W R+L + + G +E+ +
Sbjct: 3908 ------VTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNH 3961
Query: 329 SGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLR 388
+GRYTC A N GS + + L V PP V+ Q + L V+ +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPP----VIQPQP-----------SELHVILNNPIL 4006
Query: 389 LVCVTHSSPPARLSWTRWGQTVGPSQPS----DPGVLELPPIQMEHEGEFTCHAQHPLGS 444
L C +P ++W + G V S + G L++ E G + C AQ+P G+
Sbjct: 4007 LPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT 4066
Query: 445 QHVSLSLSV 453
+ L+V
Sbjct: 4067 ALGKIKLNV 4075
Score = 52.8 bits (125), Expect = 9e-07
Identities = 44/185 (23%), Positives = 82/185 (44%), Gaps = 20/185 (10%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP-WGPRTLG--LELRGVRAGDSGRYT 333
V K + + L C A+ P +++W+ D+ ++++ ++ G L++ D+GRYT
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYT 1897
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C A N G QQ + L V PP LE+ G + VL ++L C
Sbjct: 1898 CVATNAAGETQQHIQLHVHEPPS-------------LEDAGKMLNETVLVSNPVQLECKA 1944
Query: 394 HSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSL 449
+P ++W + + + S + ++++ Q+ G + C A + G+ +
Sbjct: 1945 AGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFY 2004
Query: 450 SLSVH 454
SL VH
Sbjct: 2005 SLQVH 2009
Score = 52.8 bits (125), Expect = 9e-07
Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 22/197 (11%)
Query: 265 ALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
+LE G ++ V ++L C A P ++W +R+LS S G +++
Sbjct: 1920 SLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIE 1979
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ D+G Y C A N G+ + L V P +S +N V V+
Sbjct: 1980 SAQISDAGIYKCVAINSAGATELFYSLQVHVAPS-----ISGSNNMV----------AVV 2024
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTV-----GPSQPSDPGVLELPPIQMEHEGEFTCH 437
+RL C P L+W + G V G S +L L Q+ G +TC
Sbjct: 2025 VNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCV 2084
Query: 438 AQHPLGSQHVSLSLSVH 454
A + G + + L V+
Sbjct: 2085 AVNAAGEKQRDIDLRVY 2101
Score = 52.8 bits (125), Expect = 9e-07
Identities = 68/276 (24%), Positives = 103/276 (37%), Gaps = 41/276 (14%)
Query: 187 PAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVR 244
P PS WT G L PR + + +H TC V + G SA R V
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTC-VARNAAG-SAHRHVT 3981
Query: 245 LRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDR 304
L V P +Q L V + L C A P ++W +
Sbjct: 3982 LHVHEPPV---------------IQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGI 4026
Query: 305 VLSSS---HPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVM 361
+++S H P GL++ D+G Y C A+N G+ + L+VQ PP V+
Sbjct: 4027 NVNTSGRNHAVLPSG-GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPP----VI 4081
Query: 362 VSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDP 418
V + + + L C PP ++W + G+ + S +
Sbjct: 4082 SPHLKEYV-----------IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSS 4130
Query: 419 GVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
G L++ +Q G +TC A + GS S L+VH
Sbjct: 4131 GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVH 4166
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/201 (24%), Positives = 81/201 (40%), Gaps = 31/201 (15%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGP------RTLGLELRGVRAGD 328
+ ++ G + L C P T+ W D + S P+ RT L + + A D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 329 SGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP-VLEGQSL 387
G Y C AEN+ G Q ++V V +G S+ V+EGQ L
Sbjct: 862 KGTYICEAENQFGKIQSETTVTV--------------TGLVAPLIGISPSVANVIEGQQL 907
Query: 388 RLVCVTHSSPPARLSWTRWGQTVGPSQPS------DPGVLELPPIQMEHEGEFTCHAQHP 441
L C + P + RW + + G L + +Q++ GE+TC A +
Sbjct: 908 TLPCTLLAGNP--IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNV 965
Query: 442 LGSQHVSLSLSVHW--KLEHG 460
G+ + + S+ VH ++HG
Sbjct: 966 AGTNNKTTSVVVHVLPTIQHG 986
Score = 52.0 bits (123), Expect = 2e-06
Identities = 74/309 (23%), Positives = 115/309 (37%), Gaps = 57/309 (18%)
Query: 153 TALTK-KPDVYIPETLEPGQPVTVICVFNWAFKKC-----PAPSFSW--TGAAL--SPRR 202
TAL K K +V +P + P VI V C P P +W G A+ S R+
Sbjct: 4066 TALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125
Query: 203 TRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDN 262
S+ + P H T + +V S+ + +L V P+
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANV-----AGSSSTSTKLTVHVPPR---------- 4170
Query: 263 TSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSS------SHPWGPRT 316
++ + V + L C AD P ++W + +L++ + P+G
Sbjct: 4171 -----IRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE-- 4223
Query: 317 LGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNG 376
L L V DSG YTC A N G + L+V P T E G+
Sbjct: 4224 --LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP------------TFTELPGD- 4268
Query: 377 TSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLEL--PPIQMEHEGEF 434
+ + +G+ LRL C P +L+WT + S G EL + E G +
Sbjct: 4269 --VSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTY 4326
Query: 435 TCHAQHPLG 443
C A++ +G
Sbjct: 4327 VCTAENSVG 4335
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 20/190 (10%)
Query: 267 ELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRA 326
EL G+V + KG+ LRL C A P L+W + ++ + L + V
Sbjct: 4264 ELPGDV---SLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSK 4320
Query: 327 GDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQS 386
DSG Y C AEN +G + + V+ PP V +E LG L
Sbjct: 4321 EDSGTYVCTAENSVGFVKAIGFVYVKEPP----VFKGDYPSNWIEPLGGNAILN------ 4370
Query: 387 LRLVCVTHSSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLG 443
C P + W R G + S + G L + E G++TC A + G
Sbjct: 4371 ----CEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426
Query: 444 SQHVSLSLSV 453
S+SL++
Sbjct: 4427 VVERSMSLTL 4436
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/187 (21%), Positives = 74/187 (39%), Gaps = 22/187 (11%)
Query: 275 LEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELRGVRAGDSGRY 332
+ V++G + L C +++ PP ++W R+++ S G L ++ D+G+Y
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQY 3128
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
CRA N G + L+V PP + ++E + N + L C
Sbjct: 3129 VCRAINVAGRDDKNFHLNVYVPPS----IEGPEREVIVETISN----------PVTLTCD 3174
Query: 393 THSSPPARLSWTRWGQTVGPSQP------SDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
PP ++W + + + S S L++ Q G +TC A + G
Sbjct: 3175 ATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ 3234
Query: 447 VSLSLSV 453
LS+
Sbjct: 3235 KYYFLSI 3241
Score = 50.8 bits (120), Expect = 3e-06
Identities = 62/256 (24%), Positives = 100/256 (39%), Gaps = 43/256 (16%)
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG---LELRGVRAGDSGRYTCRAENRLG 341
L C P T+ W + + SH R LG L + G D+G YTC A N G
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426
Query: 342 SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARL 401
++++ L++Q PP ++ + TV+ G + L C P +
Sbjct: 4427 VVERSMSLTLQSPP----IITLEPVETVIN-----------AGGKIILNCQATGEPQPTI 4471
Query: 402 SWTRWGQTVGPSQPSD---PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWKLE 458
+W+R G ++ + L + Q E EF C A++ +GS V + + V
Sbjct: 4472 TWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ---V 4528
Query: 459 HGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEARKRA-AAEQDVPSTLGPISQGHQ 517
HG G + A+ +C V C K +KR+ Q +P+ G QG
Sbjct: 4529 HG-----------GFSQWSAWRACSVT-----CGKGIQKRSRLCNQPLPANGGKPCQGSD 4572
Query: 518 HECSAGSSQDHPPPGA 533
E ++ P G+
Sbjct: 4573 LEMRNCQNKPCPVDGS 4588
Score = 50.1 bits (118), Expect = 6e-06
Identities = 43/174 (24%), Positives = 68/174 (39%), Gaps = 20/174 (11%)
Query: 287 CAADSQPPATLSWVLQDRVL--SSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQ 344
C + P SW + L H + L++ + D GRY C AEN GS +
Sbjct: 2894 CLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAK 2953
Query: 345 QALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWT 404
+ +L+V PP + +L V+ + L C PP LSW
Sbjct: 2954 KYFNLNVHVPPSVIG--------------PKSENLTVVVNNFISLTCEVSGFPPPDLSWL 2999
Query: 405 RWGQTV--GPSQPSDPG--VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ Q + + PG L++ ++ GE+TC A + G SL+V+
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Score = 49.3 bits (116), Expect = 1e-05
Identities = 62/284 (21%), Positives = 106/284 (37%), Gaps = 44/284 (15%)
Query: 184 KKCPAPSFSW--TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQR 241
K P P+ W G L+ R S L S +D V + G + +R
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTT-ER 1349
Query: 242 TVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVL 301
L+V P ++ + V + V Q L C + P + W
Sbjct: 1350 KYNLKVHVPP-------------VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK 1396
Query: 302 QDRVLSSSHPWGPRTLGLELRGVRAG--DSGRYTCRAENRLGSQQQALDLSVQYPPENLR 359
+ ++ S G L+ RA D+GRY+C+A N G+ Q+ ++ V PP
Sbjct: 1397 DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP---- 1452
Query: 360 VMVSQANRTVLENLGNGTSLP----VLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQP 415
T++ GT+ P V+ + + L C +P + W + G+ + P
Sbjct: 1453 --------TII-----GTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 416 S----DPG-VLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
+ D G VL L + +G + C + G Q + L+++
Sbjct: 1500 NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY 1543
Score = 48.1 bits (113), Expect = 2e-05
Identities = 64/299 (21%), Positives = 108/299 (36%), Gaps = 44/299 (14%)
Query: 166 TLEPGQPVTVICVFNWAFKKCPAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPSPQDHD 223
T+ G ++ C+ + PAPS +W G L ++H VL + +
Sbjct: 3446 TVLKGSSTSMACITDGT----PAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDS 3501
Query: 224 TDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFL 283
TC S + + L+V P H N S + +VI L
Sbjct: 3502 GKYTCIA--SNEAGEVSKHFILKVLEPP--------HINGSEEHEEISVIV-----NNPL 3546
Query: 284 RLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG----LELRGVRAGDSGRYTCRAENR 339
L C A P ++W+ R L + +TLG L + + D+GRYTC A +
Sbjct: 3547 ELTCIASGIPAPKMTWMKDGRPLPQTDQ--VQTLGGGEVLRISTAQVEDTGRYTCLASSP 3604
Query: 340 LGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPA 399
G + + V PP + + VL + + L C + + PP
Sbjct: 3605 AGDDDKEYLVRVHVPPN-------------IAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 400 RLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
++W R G+ + + S L++ + +TC A + G L+V+
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN 3710
Score = 47.8 bits (112), Expect = 3e-05
Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 18/131 (13%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG---LELRGVRAGDSGRYT 333
V G+ L C S L+W DR + + P RTL LEL+ V+ D+G Y
Sbjct: 531 VTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYH 590
Query: 334 CRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVT 393
C + GS ++ L+VQ PP +V V N++ G + ++C
Sbjct: 591 CMVSSEGGSSAASVFLTVQEPP---KVTVMPKNQS------------FTGGSEVSIMCSA 635
Query: 394 HSSPPARLSWT 404
P +++WT
Sbjct: 636 TGYPKPKIAWT 646
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 24/183 (13%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLS-SSHPWGPRTLGLELRGVRAGDSGRYTCR 335
+Q GQ + C+ DS P TLS+V L + ++ L++ V D G Y C
Sbjct: 444 LQPGQ---IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECI 500
Query: 336 AENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHS 395
A + G+ + V PP ++V ++ V G+ L C+ S
Sbjct: 501 AVSSAGTGRAQTFFDVSEPPPVIQV---------------PNNVTVTPGERAVLTCLIIS 545
Query: 396 SPPARLSWTRWGQTVGPSQPSDPGV-----LELPPIQMEHEGEFTCHAQHPLGSQHVSLS 450
+ L+W R + V ++P+ LEL ++ GE+ C GS S+
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 451 LSV 453
L+V
Sbjct: 606 LTV 608
Score = 43.1 bits (100), Expect = 7e-04
Identities = 64/316 (20%), Positives = 114/316 (36%), Gaps = 50/316 (15%)
Query: 158 KPDVYIPETLEPGQPVTVICVFNWAFKKC-------PAPSFSWTGAALSPRRTRPSTSHF 210
K +YIP +++ G T I V + K P P+ +W P + +
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDG-QPIMSSSQALYI 1597
Query: 211 SVLSFTPSPQDHDTD---LTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALE 267
+ P+ +D TCHV + +A+++ + V P
Sbjct: 1598 DKGQYLHIPRAQVSDSATYTCHV--ANVAGTAEKSFHVDVYVPPM--------------- 1640
Query: 268 LQGNV---IYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG--LELR 322
++GN+ + +V L L C A P L+W+ + ++ G LE+
Sbjct: 1641 IEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIM 1700
Query: 323 GVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 382
+ D G+Y C A + G ++ ++ V PP +E + V+
Sbjct: 1701 SAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP-------------AIEGGDETSYFIVM 1747
Query: 383 EGQSLRLVCVTHSSPPARLSWTRWGQTV----GPSQPSDPGVLELPPIQMEHEGEFTCHA 438
L L C SPP + W + GQ + G + L + Q+ + G + C A
Sbjct: 1748 VNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMA 1807
Query: 439 QHPLGSQHVSLSLSVH 454
+ G ++VH
Sbjct: 1808 ANTAGDHKKEFEVTVH 1823
Score = 39.7 bits (91), Expect = 0.008
Identities = 75/355 (21%), Positives = 123/355 (34%), Gaps = 61/355 (17%)
Query: 115 SLVIRDAQREDEAWYFFRV--ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQP 172
SL ++ + D Y V E GS FL+ KVT + K ++ G
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKN------QSFTGGSE 628
Query: 173 VTVICVFNWAFKKCPAPSFSWTGAAL----SPRRTRPSTSHFSVLSFTPSPQDHDTDLTC 228
V+++C + P P +WT + S R S + + P D +
Sbjct: 629 VSIMC----SATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPK----DAGIYG 680
Query: 229 HVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCA 288
+ + G Q + LR APK +++ + L G++ +E C
Sbjct: 681 CLASNSAGTDKQNST-LRYIEAPKLMVVQ-----SELLVALGDITVME----------CK 724
Query: 289 ADSQPPATLSWVLQDRVLSSSHPW--GPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
PP + W D L S P L+++ + D+G YTC A N G
Sbjct: 725 TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK 784
Query: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
+ L V PP + Q V +G+ +LP C P + W R
Sbjct: 785 ITLDVGSPP-----VFIQEPADVSMEIGSNVTLP----------CYVQGYPEPTIKWRRL 829
Query: 407 GQTVGPSQPSD--------PGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
S+P G L + + +G + C A++ G +++V
Sbjct: 830 DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884
Score = 29.6 bits (65), Expect = 8.3
Identities = 57/253 (22%), Positives = 92/253 (36%), Gaps = 38/253 (15%)
Query: 108 DPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETL 167
D G LVI +ED Y E F+ F+ V K+P V+ +
Sbjct: 4305 DSVNGHSELVIERVSKEDSGTYVCTAENSV----GFVKAIGFVYV----KEPPVFKGDYP 4356
Query: 168 EPG-QPVTVICVFNWAFKKCPAPSFSWT--GAALSPRRTRPSTSHFSVLSFTPSPQDHDT 224
+P+ + N K P P+ W G + + S+ + +D
Sbjct: 4357 SNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAG- 4415
Query: 225 DLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLR 284
D TC V + GV +R++ L + P II++ T + G +I
Sbjct: 4416 DYTC-VATNEAGV-VERSMSLTLQSPP---IITLEPVET-VINAGGKII----------- 4458
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHPWGPR-----TLGLELRGVRAGDSGRYTCRAENR 339
L C A +P T++W Q +S W R L + + D+ + C A N
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSIS----WDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 340 LGSQQQALDLSVQ 352
+GS + + VQ
Sbjct: 4515 MGSVLVRVPVIVQ 4527
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 73.9 bits (180), Expect = 4e-13
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 21/186 (11%)
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAE 337
+G +++ C+A P +SW + + L G L ++GV D+G Y+C+A
Sbjct: 620 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 679
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
N +G+ Q+ + L PP VS N VL V G+ LVC P
Sbjct: 680 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 724
Query: 398 PARLSWTRWG-QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVHWK 456
P R+ W R G + + + S G L +P Q G +TC A + LG + L+V
Sbjct: 725 PPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV--- 781
Query: 457 LEHGGG 462
GGG
Sbjct: 782 -GRGGG 786
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 20/180 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT--LGLELRGVRAGDSGRYTC 334
V G+ L C + P L+WV RVL +S + L LE+ G+ D GRY C
Sbjct: 527 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQC 586
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G + ++ L V+ P+ V + + +S +G +++ C
Sbjct: 587 VASNANGVTRASVWLLVREAPQ---VSI------------HTSSQHFSQGVEVKVSCSAS 631
Query: 395 SSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
P +SW+R Q + G L + + E G ++C A + +G+ +++L
Sbjct: 632 GYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 691
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 73.6 bits (179), Expect = 5e-13
Identities = 51/177 (28%), Positives = 78/177 (44%), Gaps = 17/177 (9%)
Query: 279 KGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAE 337
+G +++ C+A P +SW + + L G L ++GV D+G Y+C+A
Sbjct: 504 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 563
Query: 338 NRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSP 397
N +G+ Q+ + L PP VS N VL V G+ LVC P
Sbjct: 564 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 608
Query: 398 PARLSWTRWG-QTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSV 453
P R+ W R G + + + S G L +P Q G +TC A + LG + L+V
Sbjct: 609 PPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665
Score = 62.0 bits (149), Expect = 2e-09
Identities = 74/288 (25%), Positives = 112/288 (38%), Gaps = 47/288 (16%)
Query: 170 GQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSV-----LSFTPSPQDHDT 224
GQPV++ C+ P P W L R P S S+ L + Q+H
Sbjct: 782 GQPVSLPCI---VLAGRPLPERHW----LKDGRPLPPGSRHSIRADGSLHLDRALQEHAG 834
Query: 225 DLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLR 284
+C + S R V L V P+ + + +H T+ +G
Sbjct: 835 RYSCVA--TNTAGSQHRDVELVVQVPPR-IHPTATHHITN--------------EGVPAS 877
Query: 285 LLCAADSQPPATLSWVLQDRVLSSSHP-WGPRTLG-LELRGVRAGDSGRYTCRAENRLGS 342
L C A P T++W + L+S P + G L + A D+G Y C A N +G
Sbjct: 878 LPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGF 937
Query: 343 QQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLS 402
Q + LSV P R+ ++ + N + G+ + L C SPP ++
Sbjct: 938 SSQEMRLSVNTKP---RIHMNGSR-----NANVPLQVTAKAGEEVTLDCEAKGSPPPLVT 989
Query: 403 WTRWGQTVGPSQ------PSDPGVLELPPIQMEHEGEFTCHAQHPLGS 444
WT+ + V P PS G L L +Q+ G + C A +P GS
Sbjct: 990 WTKDSRPVPPITNRYGLLPS--GSLRLAQVQVGDSGHYECTASNPAGS 1035
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/187 (26%), Positives = 75/187 (40%), Gaps = 26/187 (13%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRA 336
V G+ L+C A PP + W + + P G + L + + D+G YTCRA
Sbjct: 592 VAVGEEAVLVCEASGVPPPRVIWYRGGLEMILA-PEGSSSGKLRIPAAQERDAGTYTCRA 650
Query: 337 ENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSS 396
N LG + L+V + P+ +++ R V L G+S L C
Sbjct: 651 VNELGDASAEIQLAVGHAPQ-----LTELPRDVTVEL----------GRSALLACRATGR 695
Query: 397 PPARLSWTRW-GQTVG---------PSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQH 446
PP ++W R GQ +G S+ D GVL + E + + C A++ G
Sbjct: 696 PPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ 755
Query: 447 VSLSLSV 453
L V
Sbjct: 756 AEARLIV 762
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 20/180 (11%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRT--LGLELRGVRAGDSGRYTC 334
V G+ L C + P L+WV RVL +S + L LE+ G+ D GRY C
Sbjct: 411 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQC 470
Query: 335 RAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH 394
A N G + ++ L V+ P+ V + + +S +G +++ C
Sbjct: 471 VASNANGVTRASVWLLVREAPQ---VSI------------HTSSQHFSQGVEVKVSCSAS 515
Query: 395 SSPPARLSWTRWGQTVGPS---QPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSL 451
P +SW+R Q + G L + + E G ++C A + +G+ +++L
Sbjct: 516 GYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 575
Score = 50.4 bits (119), Expect = 5e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 21/188 (11%)
Query: 275 LEVQKGQFLRLLCAA-DSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRY 332
+ V +GQ + L C +P W+ R L R G L L +GRY
Sbjct: 777 VRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRY 836
Query: 333 TCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCV 392
+C A N GSQ + ++L VQ PP + + T ++ N EG L CV
Sbjct: 837 SCVATNTAGSQHRDVELVVQVPP--------RIHPTATHHITN-------EGVPASLPCV 881
Query: 393 THSSPPARLSWTRWGQTVGPSQP----SDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVS 448
P ++WT+ + P S G L + + G + C A + +G
Sbjct: 882 ASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQE 941
Query: 449 LSLSVHWK 456
+ LSV+ K
Sbjct: 942 MRLSVNTK 949
Score = 50.1 bits (118), Expect = 6e-06
Identities = 65/238 (27%), Positives = 102/238 (42%), Gaps = 31/238 (13%)
Query: 170 GQPVTVICVFNWAFKKCPAPSFSWTGA--ALSPRRTRPSTSHFSVLSFTPSPQDHDTDLT 227
G P ++ CV + PAP+ +WT AL+ R + S L P D
Sbjct: 873 GVPASLPCVASGV----PAPTITWTKETNALTSRGPHYNVSKEGTLLIA-QPSAQDAGAY 927
Query: 228 CHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLC 287
+ G S+Q +RL V P+ I ++ + + LQ + + G+ + L C
Sbjct: 928 VCTATNTVGFSSQE-MRLSVNTKPR---IHMNGSRNANVPLQ-----VTAKAGEEVTLDC 978
Query: 288 AADSQPPATLSWVLQDR-VLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAENRLGSQQQ 345
A PP ++W R V ++ +G G L L V+ GDSG Y C A N GS
Sbjct: 979 EAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASH 1038
Query: 346 ALDLSVQ----YPPENLRVMVSQANRTVLENLGNGTSLPVLE--GQSLRLVCVTHSSP 397
L VQ + P++L V A +G S+P+L+ +S+RL ++ +P
Sbjct: 1039 RYVLGVQGRTSWQPQSLPVPHHPA-------CLSGLSVPLLQPTPRSVRLCHLSLRAP 1089
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 73.6 bits (179), Expect = 5e-13
Identities = 53/186 (28%), Positives = 83/186 (44%), Gaps = 26/186 (13%)
Query: 276 EVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTL-----GLELRGVRAGDSG 330
EV G+ + L C+A PP +SW DR + P PR GL ++ V GDSG
Sbjct: 352 EVLVGESVTLECSATGHPPPRISWTRGDR---TPLPVDPRVNITPSGGLYIQNVVQGDSG 408
Query: 331 RYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLV 390
Y C A N + S + VQ P+ V+ +R V+EGQ++
Sbjct: 409 EYACSATNNIDSVHATAFIIVQALPQ---FTVTPQDRV------------VIEGQTVDFQ 453
Query: 391 CVTHSSPPARLSWTRWGQTVGPSQPS---DPGVLELPPIQMEHEGEFTCHAQHPLGSQHV 447
C +PP ++WT+ G + + G L + + + +G++ C A + +GSQ V
Sbjct: 454 CEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKV 513
Query: 448 SLSLSV 453
L+V
Sbjct: 514 VAHLTV 519
Score = 67.8 bits (164), Expect = 3e-11
Identities = 97/405 (23%), Positives = 157/405 (38%), Gaps = 49/405 (12%)
Query: 57 SYPRDGWDESTAAYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSL 116
S P+D + T+ +F R + + E+ M T R L D +L
Sbjct: 250 SEPQDA--DVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-----TL 302
Query: 117 VIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTKKPDVYI-PETLEP--GQPV 173
+I++ Q D+ Y + V + L+ +P I P+ E G+ V
Sbjct: 303 MIQNTQETDQGIYQCMAKN---VAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 359
Query: 174 TVICVFNWAFKKCPAPSFSWTGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFS 233
T+ C + P P SWT +P P ++ TPS + ++ D
Sbjct: 360 TLEC----SATGHPPPRISWTRGDRTPLPVDPR------VNITPSGGLYIQNVV-QGDSG 408
Query: 234 RKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLLCAADSQP 293
SA T + +A +I+ T + Q V+ +GQ + C A P
Sbjct: 409 EYACSA--TNNIDSVHATAFIIVQALPQFT--VTPQDRVVI----EGQTVDFQCEAKGNP 460
Query: 294 PATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQ 352
P ++W LS + G L + GV D G+Y C+A N +GSQ+ L+VQ
Sbjct: 461 PPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 520
Query: 353 YPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTV-- 410
P V S + T +E G +++L C + P ++W + G V
Sbjct: 521 --PRVTPVFASIPSDTTVE-----------VGANVQLPCSSQGEPEPAITWNKDGVQVTE 567
Query: 411 -GPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLGSQHVSLSLSVH 454
G S G L + + G + C A++ +GS VS+ LSV+
Sbjct: 568 SGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVN 612
Score = 38.9 bits (89), Expect = 0.014
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 277 VQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLG-LELRGVRAGDSGRYTCR 335
V+ G ++L C++ +P ++W ++ S + G L + V D+GRY C
Sbjct: 536 VEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECV 595
Query: 336 AENRLGSQQQALDLSVQYP 354
A N +GS ++ LSV P
Sbjct: 596 ARNTIGSASVSMVLSVNVP 614
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,296,590
Number of Sequences: 37866
Number of extensions: 1407888
Number of successful extensions: 6867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 223
Number of HSP's that attempted gapping in prelim test: 4297
Number of HSP's gapped (non-prelim): 1647
length of query: 602
length of database: 18,247,518
effective HSP length: 108
effective length of query: 494
effective length of database: 14,157,990
effective search space: 6994047060
effective search space used: 6994047060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.