Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 205360956
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205360956 cysteine-rich with EGF-like domains 2 isoform a
[Homo sapiens]
(402 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205360956 cysteine-rich with EGF-like domains 2 isoform a [Ho... 886 0.0
gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Ho... 753 0.0
gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3 [Ho... 352 3e-97
gi|72534728 cysteine-rich with EGF-like domains 1 isoform 1 [Hom... 352 3e-97
gi|22095397 cysteine-rich with EGF-like domains 1 isoform 2 [Hom... 352 3e-97
gi|61743980 stabilin 2 precursor [Homo sapiens] 92 8e-19
gi|110347437 latent transforming growth factor beta binding prot... 83 4e-16
gi|110347412 latent transforming growth factor beta binding prot... 83 4e-16
gi|110347431 latent transforming growth factor beta binding prot... 83 4e-16
gi|24430141 fibrillin 1 precursor [Homo sapiens] 82 1e-15
gi|61743978 stabilin 1 precursor [Homo sapiens] 81 2e-15
gi|66346695 fibrillin 2 precursor [Homo sapiens] 79 6e-15
gi|56237021 fibrillin 3 precursor [Homo sapiens] 79 7e-15
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 79 7e-15
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 79 9e-15
gi|115298674 nidogen 1 precursor [Homo sapiens] 79 9e-15
gi|144953895 nidogen 2 precursor [Homo sapiens] 78 1e-14
gi|194328809 latent transforming growth factor beta binding prot... 77 2e-14
gi|18497288 latent transforming growth factor beta binding prote... 77 2e-14
gi|19743803 fibulin 5 precursor [Homo sapiens] 77 2e-14
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 77 3e-14
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 77 3e-14
gi|34734066 fibulin 1 isoform D [Homo sapiens] 77 3e-14
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 77 3e-14
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 76 5e-14
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 75 8e-14
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 74 2e-13
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 74 2e-13
gi|75709198 nephronectin [Homo sapiens] 74 2e-13
gi|88758613 CD93 antigen precursor [Homo sapiens] 74 2e-13
>gi|205360956 cysteine-rich with EGF-like domains 2 isoform a [Homo
sapiens]
Length = 402
Score = 886 bits (2290), Expect = 0.0
Identities = 402/402 (100%), Positives = 402/402 (100%)
Query: 1 MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAW 60
MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAW
Sbjct: 1 MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAW 60
Query: 61 EEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFC 120
EEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFC
Sbjct: 61 EEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFC 120
Query: 121 VKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDC 180
VKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDC
Sbjct: 121 VKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDC 180
Query: 181 MDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVW 240
MDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVW
Sbjct: 181 MDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVW 240
Query: 241 IAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNAN 300
IAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNAN
Sbjct: 241 IAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNAN 300
Query: 301 GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT 360
GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT
Sbjct: 301 GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT 360
Query: 361 PGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL 402
PGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL
Sbjct: 361 PGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL 402
>gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Homo
sapiens]
Length = 353
Score = 753 bits (1945), Expect = 0.0
Identities = 353/402 (87%), Positives = 353/402 (87%), Gaps = 49/402 (12%)
Query: 1 MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAW 60
MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAW
Sbjct: 1 MRLPRRAALGLLPLLLLLPPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAW 60
Query: 61 EEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFC 120
EEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFC
Sbjct: 61 EEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFC 120
Query: 121 VKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDC 180
VKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDC
Sbjct: 121 VKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDC 180
Query: 181 MDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVW 240
MDGYFSSLRNETHSICT
Sbjct: 181 MDGYFSSLRNETHSICT------------------------------------------- 197
Query: 241 IAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNAN 300
ACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNAN
Sbjct: 198 ------ACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNAN 251
Query: 301 GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT 360
GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT
Sbjct: 252 GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT 311
Query: 361 PGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL 402
PGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL
Sbjct: 312 PGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL 353
>gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3 [Homo
sapiens]
Length = 420
Score = 352 bits (903), Expect = 3e-97
Identities = 157/362 (43%), Positives = 202/362 (55%), Gaps = 51/362 (14%)
Query: 19 PPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEI 78
PP +P PCH CRGLVD FN+G+ T + NFGGGNTAWEE+ LSKY+ SE RL+E+
Sbjct: 34 PPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEV 93
Query: 79 LEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCL 138
LEG+C SDFEC+++LE EE +E+WW + E PDLF+W C +LK+CC GT+GP CL
Sbjct: 94 LEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCL 153
Query: 139 ACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTV 198
C GG++RPC G G C G+G+R G G C C GY G C C GYF + RN +H +C+
Sbjct: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCS- 212
Query: 199 RTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGL 258
AC C CSG
Sbjct: 213 ------------------------------------------------ACFGPCARCSGP 224
Query: 259 TNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGE 318
+C +C+ GW L CVD+DEC E C A QFC N GSY C +C +C+GC G
Sbjct: 225 EESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGA 284
Query: 319 GPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA 378
GPG CK+C GY + +C DVDEC + C +N+ C NT G Y C+C +G+++ E
Sbjct: 285 GPGRCKKCSPGYQQVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQMEGI 342
Query: 379 CV 380
CV
Sbjct: 343 CV 344
Score = 67.8 bits (164), Expect = 2e-11
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 38/174 (21%)
Query: 251 SCKTCSGLTNRDCG---ECEVGWVLDEGACVDVDECAAEPP-------PCSAAQFCKNAN 300
SC C G T R CG +CE EG C + C F N
Sbjct: 151 SCLPCPGGTERPCGGYGQCE-----GEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERN 205
Query: 301 GSY-TCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYN 359
S+ C C C C+G NC +C G+A H +C D+DEC C ++ C N
Sbjct: 206 ASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANC-GADQFCVN 264
Query: 360 TPGSYVC-------------------VCPDGFEETEDAC--VPPAEAEATEGES 392
T GSY C C G+++ C V E E GE+
Sbjct: 265 TEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGEN 318
>gi|72534728 cysteine-rich with EGF-like domains 1 isoform 1 [Homo
sapiens]
Length = 422
Score = 352 bits (903), Expect = 3e-97
Identities = 157/362 (43%), Positives = 202/362 (55%), Gaps = 51/362 (14%)
Query: 19 PPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEI 78
PP +P PCH CRGLVD FN+G+ T + NFGGGNTAWEE+ LSKY+ SE RL+E+
Sbjct: 34 PPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEV 93
Query: 79 LEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCL 138
LEG+C SDFEC+++LE EE +E+WW + E PDLF+W C +LK+CC GT+GP CL
Sbjct: 94 LEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCL 153
Query: 139 ACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTV 198
C GG++RPC G G C G+G+R G G C C GY G C C GYF + RN +H +C+
Sbjct: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCS- 212
Query: 199 RTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGL 258
AC C CSG
Sbjct: 213 ------------------------------------------------ACFGPCARCSGP 224
Query: 259 TNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGE 318
+C +C+ GW L CVD+DEC E C A QFC N GSY C +C +C+GC G
Sbjct: 225 EESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGA 284
Query: 319 GPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA 378
GPG CK+C GY + +C DVDEC + C +N+ C NT G Y C+C +G+++ E
Sbjct: 285 GPGRCKKCSPGYQQVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQMEGI 342
Query: 379 CV 380
CV
Sbjct: 343 CV 344
Score = 67.8 bits (164), Expect = 2e-11
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 38/174 (21%)
Query: 251 SCKTCSGLTNRDCG---ECEVGWVLDEGACVDVDECAAEPP-------PCSAAQFCKNAN 300
SC C G T R CG +CE EG C + C F N
Sbjct: 151 SCLPCPGGTERPCGGYGQCE-----GEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERN 205
Query: 301 GSY-TCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYN 359
S+ C C C C+G NC +C G+A H +C D+DEC C ++ C N
Sbjct: 206 ASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANC-GADQFCVN 264
Query: 360 TPGSYVC-------------------VCPDGFEETEDAC--VPPAEAEATEGES 392
T GSY C C G+++ C V E E GE+
Sbjct: 265 TEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGEN 318
>gi|22095397 cysteine-rich with EGF-like domains 1 isoform 2 [Homo
sapiens]
Length = 420
Score = 352 bits (903), Expect = 3e-97
Identities = 157/362 (43%), Positives = 202/362 (55%), Gaps = 51/362 (14%)
Query: 19 PPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEI 78
PP +P PCH CRGLVD FN+G+ T + NFGGGNTAWEE+ LSKY+ SE RL+E+
Sbjct: 34 PPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEV 93
Query: 79 LEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCL 138
LEG+C SDFEC+++LE EE +E+WW + E PDLF+W C +LK+CC GT+GP CL
Sbjct: 94 LEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCL 153
Query: 139 ACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTV 198
C GG++RPC G G C G+G+R G G C C GY G C C GYF + RN +H +C+
Sbjct: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCS- 212
Query: 199 RTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGL 258
AC C CSG
Sbjct: 213 ------------------------------------------------ACFGPCARCSGP 224
Query: 259 TNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGE 318
+C +C+ GW L CVD+DEC E C A QFC N GSY C +C +C+GC G
Sbjct: 225 EESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGA 284
Query: 319 GPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA 378
GPG CK+C GY + +C DVDEC + C +N+ C NT G Y C+C +G+++ E
Sbjct: 285 GPGRCKKCSPGYQQVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQMEGI 342
Query: 379 CV 380
CV
Sbjct: 343 CV 344
Score = 67.8 bits (164), Expect = 2e-11
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 38/174 (21%)
Query: 251 SCKTCSGLTNRDCG---ECEVGWVLDEGACVDVDECAAEPP-------PCSAAQFCKNAN 300
SC C G T R CG +CE EG C + C F N
Sbjct: 151 SCLPCPGGTERPCGGYGQCE-----GEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERN 205
Query: 301 GSY-TCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYN 359
S+ C C C C+G NC +C G+A H +C D+DEC C ++ C N
Sbjct: 206 ASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANC-GADQFCVN 264
Query: 360 TPGSYVC-------------------VCPDGFEETEDAC--VPPAEAEATEGES 392
T GSY C C G+++ C V E E GE+
Sbjct: 265 TEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGEN 318
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 92.0 bits (227), Expect = 8e-19
Identities = 77/270 (28%), Positives = 103/270 (38%), Gaps = 41/270 (15%)
Query: 119 FCVKTLKV--CCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL 176
+C T+K+ CC G YGPDC C GG PCSGNG C+ S G+G+C C G+QG
Sbjct: 718 YCNATVKIPKCCK-GFYGPDCNQCPGGFSNPCSGNGQCA--DSLGGNGTCICEEGFQGSQ 774
Query: 177 CTDCMDGYFSSLRNETHSICTVRT--GLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPG 234
C C D R +C T DS CL+ C G + + P
Sbjct: 775 CQFCSDPNKYGPRCNKKCLCVHGTCNNRIDS-DGACLTGTCRDGSAGRLCDKQTSACGP- 832
Query: 235 YSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAA-EPPPCSA- 292
V C+ S T S + C+ G+ D C ++D C P CS
Sbjct: 833 ---YVQFCHIHATCEYSNGTASCI-------CKAGYEGDGTLCSEMDPCTGLTPGGCSRN 882
Query: 293 AQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVR 352
A+ K G++TC C G+ C++++ C L
Sbjct: 883 AECIKTGTGTHTC-------------------VCQQGWTGNGRDCSEINNCLLPSAGGCH 923
Query: 353 KNENC-YNTPGSYVCVCPDGFEETEDACVP 381
N +C Y PG C C GF C P
Sbjct: 924 DNASCLYVGPGQNECECKKGFRGNGIDCEP 953
Score = 86.7 bits (213), Expect = 3e-17
Identities = 65/249 (26%), Positives = 95/249 (38%), Gaps = 39/249 (15%)
Query: 128 CSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSS 187
C PG +GPDC+ C GG+ PC+G G C+ +G+G+C C G+ G C C D
Sbjct: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCA--EGMEGNGTCSCQEGFGGTACETCAD----- 152
Query: 188 LRNETHSICTVRTGLSDSYPPCCLSL-GCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSP 246
+ + P C S+ C GV ++ + G T + A P
Sbjct: 153 ---------------DNLFGPSCSSVCNCVHGVCNSGLDGDGT-------CECYSAYTGP 190
Query: 247 ACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE 306
CD+ C+ L + C DE EC P ++C N
Sbjct: 191 KCDKPIPECAALLCPENSRCSPS-TEDENKL----ECKCLPNYRGDGKYCDPINP--CLR 243
Query: 307 ECDSSCVGCTGEGPG-NCKECISGYAREHGQCADVDECSLAEKTCVRKNENC-YNTPGSY 364
+ CT GP + C GY + C VD C + C K+ C Y+ PG
Sbjct: 244 KICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQS 303
Query: 365 VCVCPDGFE 373
C C + ++
Sbjct: 304 HCECKEHYQ 312
Score = 73.6 bits (179), Expect = 3e-13
Identities = 68/276 (24%), Positives = 88/276 (31%), Gaps = 81/276 (29%)
Query: 128 CSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSS 187
C G +G DC AC GG PC+ G C S G+ C+C+ G+ G C C G F
Sbjct: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGE--CKCNTGFNGTACEMCWPGRFG- 2006
Query: 188 LRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPA 247
P CL GC + H Q
Sbjct: 2007 --------------------PDCLPCGC------------SDHGQ--------------- 2019
Query: 248 CDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDEC--AAEPPPCSAAQFCKNAN----- 300
CD+ G+T CE GW G D A PPCSA CK N
Sbjct: 2020 CDD------GITGSGQCLCETGWT---GPSCDTQAVLPAVCTPPCSAHATCKENNTCECN 2070
Query: 301 -----GSYTCEECD---------SSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLA 346
TC D + C+ +G C GY + C ++D C+
Sbjct: 2071 LDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADG 2130
Query: 347 EKTCVRKNENCYNT-PGSYVCVCPDGFEETEDACVP 381
++ C T PG + C C + C P
Sbjct: 2131 LNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
Score = 72.0 bits (175), Expect = 9e-13
Identities = 71/272 (26%), Positives = 98/272 (36%), Gaps = 57/272 (20%)
Query: 120 CVKTL--KVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLC 177
CV+T+ + CC+ G +GP C C G +Q C GNG C DG G G C C G+ G C
Sbjct: 1327 CVRTVITRECCA-GFFGPQCQPCPGNAQNVCFGNGICL-DGV-NGTGVCECGEGFSGTAC 1383
Query: 178 TDCMDGYFSSLRNETHSICTVRTGLSDSYP----PCCLSLGCWRGVGHAWIRGRNTHTQP 233
C +G + C+ G + P C +G WRGV N T+
Sbjct: 1384 ETCTEGKYGI---HCDQACSCVHGRCNQGPLGDGSCDCDVG-WRGV-----HCDNATTED 1434
Query: 234 GYSSRVWIAAFSPACDESCKTCSG-LTNRD---CGECEVGWVLDEGACVDVDECAAEPPP 289
C+ +C T + LTN D +C G+ + C ++ C
Sbjct: 1435 N-------------CNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG 1481
Query: 290 CSAAQFCKNAN-GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEK 348
CSA CK G C C +GY + C +++ C
Sbjct: 1482 CSAKADCKRTTPGRRVC-------------------TCKAGYTGDGIVCLEINPCLENHG 1522
Query: 349 TCVRKNENCYNT-PGSYVCVCPDGFEETEDAC 379
C KN C T P C C + C
Sbjct: 1523 GC-DKNAECTQTGPNQAACNCLPAYTGDGKVC 1553
Score = 42.4 bits (98), Expect = 8e-04
Identities = 62/286 (21%), Positives = 91/286 (31%), Gaps = 69/286 (24%)
Query: 117 EWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL 176
E F + C P YGP C +++ +G C + DG+C L
Sbjct: 768 EGFQGSQCQFCSDPNKYGPRC------NKKCLCVHGTC--NNRIDSDGAC---------L 810
Query: 177 CTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYS 236
C DG L ++ S C + C S G + A G T
Sbjct: 811 TGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGT------- 863
Query: 237 SRVWIAAFSPACDESCKTCSGLTNRDCGE---------------CEVGWVLDEGACVDVD 281
C E C+GLT C C+ GW + C +++
Sbjct: 864 ----------LCSE-MDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEIN 912
Query: 282 ECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVD 341
C +A G + ++SC+ G G C EC G+ C +
Sbjct: 913 NC-----------LLPSAGGCHD----NASCL-YVGPGQNEC-ECKKGFRGNGIDCEPIT 955
Query: 342 ECSLAEKTCVRKNENCYNT-PGSYVCVCPDGFEETEDACVPPAEAE 386
C C +C +T G + CVC +G+E C A E
Sbjct: 956 SCLEQTGKC-HPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAAVE 1000
Score = 35.0 bits (79), Expect = 0.12
Identities = 39/150 (26%), Positives = 55/150 (36%), Gaps = 25/150 (16%)
Query: 252 CKTCSGLTNRDCGECEVGWVLDEGACVD------VDECAAEPPPCSAAQFCKNANGSYTC 305
C+ C G C G C+D V EC E +A + C C
Sbjct: 1345 CQPCPGNAQNVC--------FGNGICLDGVNGTGVCECG-EGFSGTACETCTEGKYGIHC 1395
Query: 306 EECDSSCVGCTGEGP---GNCKECISGYAREHGQCADV-DECSLAEKTCVRKNENCY-NT 360
++ S G +GP G+C +C G+ H A D C+ TC + NC N+
Sbjct: 1396 DQACSCVHGRCNQGPLGDGSC-DCDVGWRGVHCDNATTEDNCN---GTC-HTSANCLTNS 1450
Query: 361 PGSYVCVCPDGFEETEDACVPPAEAEATEG 390
G+ C C GF+ C E + G
Sbjct: 1451 DGTASCKCAAGFQGNGTICTAINACEISNG 1480
Score = 33.9 bits (76), Expect = 0.27
Identities = 40/165 (24%), Positives = 51/165 (30%), Gaps = 53/165 (32%)
Query: 248 CDESC-------KTCSGLTNRDCGECEVG---WVLDEGACVDVDECAAEPPPCSAAQFCK 297
C E C + C G RDC C G + G C+D E C C
Sbjct: 1937 CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGE---CK----CN 1989
Query: 298 NANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENC 357
CE C G +C+ +HGQC D
Sbjct: 1990 TGFNGTACEMCWPGRFG---------PDCLPCGCSDHGQCDD------------------ 2022
Query: 358 YNTPGSYVCVCPDGFE----ETE----DACVPPAEAEATEGESPT 394
GS C+C G+ +T+ C PP A AT E+ T
Sbjct: 2023 -GITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT 2066
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 83.2 bits (204), Expect = 4e-16
Identities = 89/325 (27%), Positives = 122/325 (37%), Gaps = 77/325 (23%)
Query: 140 CQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL-----CTD---CMDGYF-----S 186
C G+ PC +GHC+ + +G C C GY+ P C D C++G F
Sbjct: 771 CSSGAP-PCGPHGHCT---NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 826
Query: 187 SLRNETHSICTVRTGLSDSYPP-----CCLSLG-------CWRGVGHAWIRGRNTHTQPG 234
L + CT G Y P CL + C G+ PG
Sbjct: 827 CLNTDGSFACTCAPG----YRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 882
Query: 235 YSSRVWIAAF---------SPAC--DESCKTCSGLTNRDCGECEVGWVLD-EGACVDVDE 282
+ + +A+ PA + C+ G + R +C+ G+ EG C DVDE
Sbjct: 883 HRAGPDLASCLDVDECRERGPALCGSQRCENSPG-SYRCVRDCDPGYHAGPEGTCDDVDE 941
Query: 283 CAAEPPPCSAAQFCKNANGSYTC-EECDSSCVGCTGEGPGNCKECIS------------- 328
C P AQ C+N GSY C CD G G + EC +
Sbjct: 942 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
Query: 329 ----------GY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETE 376
GY AR+ C DV+EC + C C N GS++CVCP+ EE +
Sbjct: 1002 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC--GAALCENVEGSFLCVCPNSPEEFD 1059
Query: 377 ---DACVPPAEAEATEGESPTQLPS 398
CVPP + T S Q P+
Sbjct: 1060 PMTGRCVPPRTSAGTFPGSQPQAPA 1084
Score = 80.9 bits (198), Expect = 2e-15
Identities = 85/307 (27%), Positives = 115/307 (37%), Gaps = 67/307 (21%)
Query: 123 TLKVCCSPG-TYGPDCLACQGGSQ-----RPCSGNGHCSGDGSRQGDGSCRCHMGYQG-P 175
+ + C PG GP C + PC G C + G C C GYQ P
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD-LGRCE---NTPGSFLCVCPAGYQAAP 597
Query: 176 LCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSL-GCWRGVGHAWIRGRNTHTQPG 234
C D CT GL C +L G +R V A RG
Sbjct: 598 HGASCQDV----------DECTQSPGLCGR--GACKNLPGSFRCVCPAGFRGSACEEDVD 645
Query: 235 YSSRVWIAAFSPACDES-----CKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPP 289
++ CD + C +G +R G C DVDECA PPP
Sbjct: 646 ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG----------APCQDVDECARSPPP 695
Query: 290 CSAAQFCKNANGSYTC------------------EECDSSCVGCTGE----GPGN--CKE 325
C+ + C+N GS+ C +EC++ + C G+ PG+ C+
Sbjct: 696 CTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENH-LACPGQECVNSPGSFQCRT 753
Query: 326 CISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEA 385
C SG+ G+C DVDECS C + +C NT GS+ C C G+ P A+
Sbjct: 754 CPSGHHLHRGRCTDVDECSSGAPPC-GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 812
Query: 386 -EATEGE 391
E EG+
Sbjct: 813 NECLEGD 819
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/313 (26%), Positives = 107/313 (34%), Gaps = 71/313 (22%)
Query: 126 VCCSPGTY-----GPDCLACQGGSQRP-CSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTD 179
+C P Y G C +Q P G G C + G C C G++G C +
Sbjct: 586 LCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACK---NLPGSFRCVCPAGFRGSACEE 642
Query: 180 -----------CMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRN 228
C G + H C PC C R GR
Sbjct: 643 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRC 701
Query: 229 THTQPGYSSRVWIAAFSP-----ACDE--SCKT---CSGLT------NRDCGECEVGWVL 272
+T+ + V F P C++ C+ C G + C C G L
Sbjct: 702 ENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 760
Query: 273 DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC---KECISG 329
G C DVDEC++ PPC C N GS+ C C +G PG C EC+ G
Sbjct: 761 HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC-SCAPGYRAPSGR-PGPCADVNECLEG 818
Query: 330 -YAREHGQ------------------------CADVDECSLAEKTCVRKNENCYNTPGSY 364
+ HG+ C DVDECS E C ++ C NT GS+
Sbjct: 819 DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLC--QSGICTNTDGSF 875
Query: 365 VCVCPDGFEETED 377
C+CP G D
Sbjct: 876 ECICPPGHRAGPD 888
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/154 (35%), Positives = 68/154 (44%), Gaps = 43/154 (27%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTC------------------ 305
C+ G+ L C+DVDEC PPPC+ + C+N+ GS+ C
Sbjct: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECLDV 563
Query: 306 EECDSSCVGCTGEGPGNCKE--------CISGY-AREHG-QCADVDECSLAEKTCVRKNE 355
+EC C G C+ C +GY A HG C DVDEC+ + C R
Sbjct: 564 DECHRVPPPC---DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR--G 618
Query: 356 NCYNTPGSYVCVCPDGF-----EETEDACV--PP 382
C N PGS+ CVCP GF EE D C PP
Sbjct: 619 ACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP 652
Score = 57.8 bits (138), Expect = 2e-08
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query: 282 ECAAEPPPCSAAQFCKN----ANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQC 337
ECA+ P + C A G + C+ C S +G + C +G+ R +G C
Sbjct: 230 ECASPLPGLRTQEVCCRGAGLAWGVHDCQLC-SERLGNSERVSAPDGPCPTGFERVNGSC 288
Query: 338 ADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF--EETEDACV 380
DVDEC+ + ++ C NT G Y CVCPDGF + + +C+
Sbjct: 289 EDVDECATGGRC---QHGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 13/87 (14%)
Query: 306 EECD--SSCVG--CTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKT---CVRKNEN 356
EEC C C G C GY + + C D++EC AE CV N
Sbjct: 1468 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV--NAR 1525
Query: 357 CYNTPGSYVCVCPDGFEETEDA--CVP 381
C NT GS+ C+C GF T C P
Sbjct: 1526 CLNTDGSFRCICRPGFAPTHQPHHCAP 1552
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 315 CTGEGPGNCKECISGYA--REHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVC 368
C PG C +GY + +C D DEC+ E C + C NT GSY C C
Sbjct: 1203 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC--EGGRCVNTVGSYHCTC 1256
Score = 36.6 bits (83), Expect = 0.041
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 12/70 (17%)
Query: 264 GECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTC--------EECDSSCVG- 314
G C G+ G+C DVDECA C + C N G YTC + SSC+
Sbjct: 275 GPCPTGFERVNGSCEDVDECAT-GGRCQHGE-CANTRGGYTCVCPDGFLLDSSRSSCISQ 332
Query: 315 -CTGEGPGNC 323
E G C
Sbjct: 333 HVISEAKGPC 342
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 277 CVDVDECAAEPPPCSAAQFCKNANGSYTC 305
C+D DECA E P C + C N GSY C
Sbjct: 1227 CIDNDECADEEPACEGGR-CVNTVGSYHC 1254
Score = 33.9 bits (76), Expect = 0.27
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 14/69 (20%)
Query: 250 ESCKTCSGLTNRDCGE--------CEVGWVLD--EGACVDVDEC---AAEPPPCSAAQFC 296
E C G TN C C G+ LD ACVD++EC A P C A+ C
Sbjct: 1468 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR-C 1526
Query: 297 KNANGSYTC 305
N +GS+ C
Sbjct: 1527 LNTDGSFRC 1535
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Query: 329 GYAREHGQCA---DVDECSL-AEKTCVRKNENCYNTPGSYVCVCPDGF 372
GY G + DVDEC L ++ C K+ C NT Y C C +G+
Sbjct: 1173 GYLAPSGDLSLRRDVDECQLFRDQVC--KSGVCVNTAPGYSCYCSNGY 1218
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 83.2 bits (204), Expect = 4e-16
Identities = 89/325 (27%), Positives = 122/325 (37%), Gaps = 77/325 (23%)
Query: 140 CQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL-----CTD---CMDGYF-----S 186
C G+ PC +GHC+ + +G C C GY+ P C D C++G F
Sbjct: 801 CSSGAP-PCGPHGHCT---NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 856
Query: 187 SLRNETHSICTVRTGLSDSYPP-----CCLSLG-------CWRGVGHAWIRGRNTHTQPG 234
L + CT G Y P CL + C G+ PG
Sbjct: 857 CLNTDGSFACTCAPG----YRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 912
Query: 235 YSSRVWIAAF---------SPAC--DESCKTCSGLTNRDCGECEVGWVLD-EGACVDVDE 282
+ + +A+ PA + C+ G + R +C+ G+ EG C DVDE
Sbjct: 913 HRAGPDLASCLDVDECRERGPALCGSQRCENSPG-SYRCVRDCDPGYHAGPEGTCDDVDE 971
Query: 283 CAAEPPPCSAAQFCKNANGSYTC-EECDSSCVGCTGEGPGNCKECIS------------- 328
C P AQ C+N GSY C CD G G + EC +
Sbjct: 972 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1031
Query: 329 ----------GY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETE 376
GY AR+ C DV+EC + C C N GS++CVCP+ EE +
Sbjct: 1032 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC--GAALCENVEGSFLCVCPNSPEEFD 1089
Query: 377 ---DACVPPAEAEATEGESPTQLPS 398
CVPP + T S Q P+
Sbjct: 1090 PMTGRCVPPRTSAGTFPGSQPQAPA 1114
Score = 80.9 bits (198), Expect = 2e-15
Identities = 85/307 (27%), Positives = 115/307 (37%), Gaps = 67/307 (21%)
Query: 123 TLKVCCSPG-TYGPDCLACQGGSQ-----RPCSGNGHCSGDGSRQGDGSCRCHMGYQG-P 175
+ + C PG GP C + PC G C + G C C GYQ P
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD-LGRCE---NTPGSFLCVCPAGYQAAP 627
Query: 176 LCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSL-GCWRGVGHAWIRGRNTHTQPG 234
C D CT GL C +L G +R V A RG
Sbjct: 628 HGASCQDV----------DECTQSPGLCGR--GACKNLPGSFRCVCPAGFRGSACEEDVD 675
Query: 235 YSSRVWIAAFSPACDES-----CKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPP 289
++ CD + C +G +R G C DVDECA PPP
Sbjct: 676 ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG----------APCQDVDECARSPPP 725
Query: 290 CSAAQFCKNANGSYTC------------------EECDSSCVGCTGE----GPGN--CKE 325
C+ + C+N GS+ C +EC++ + C G+ PG+ C+
Sbjct: 726 CTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENH-LACPGQECVNSPGSFQCRT 783
Query: 326 CISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEA 385
C SG+ G+C DVDECS C + +C NT GS+ C C G+ P A+
Sbjct: 784 CPSGHHLHRGRCTDVDECSSGAPPC-GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 842
Query: 386 -EATEGE 391
E EG+
Sbjct: 843 NECLEGD 849
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/313 (26%), Positives = 107/313 (34%), Gaps = 71/313 (22%)
Query: 126 VCCSPGTY-----GPDCLACQGGSQRP-CSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTD 179
+C P Y G C +Q P G G C + G C C G++G C +
Sbjct: 616 LCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACK---NLPGSFRCVCPAGFRGSACEE 672
Query: 180 -----------CMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRN 228
C G + H C PC C R GR
Sbjct: 673 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRC 731
Query: 229 THTQPGYSSRVWIAAFSP-----ACDE--SCKT---CSGLT------NRDCGECEVGWVL 272
+T+ + V F P C++ C+ C G + C C G L
Sbjct: 732 ENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 790
Query: 273 DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC---KECISG 329
G C DVDEC++ PPC C N GS+ C C +G PG C EC+ G
Sbjct: 791 HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC-SCAPGYRAPSGR-PGPCADVNECLEG 848
Query: 330 -YAREHGQ------------------------CADVDECSLAEKTCVRKNENCYNTPGSY 364
+ HG+ C DVDECS E C ++ C NT GS+
Sbjct: 849 DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLC--QSGICTNTDGSF 905
Query: 365 VCVCPDGFEETED 377
C+CP G D
Sbjct: 906 ECICPPGHRAGPD 918
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/154 (35%), Positives = 68/154 (44%), Gaps = 43/154 (27%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTC------------------ 305
C+ G+ L C+DVDEC PPPC+ + C+N+ GS+ C
Sbjct: 535 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECLDV 593
Query: 306 EECDSSCVGCTGEGPGNCKE--------CISGY-AREHG-QCADVDECSLAEKTCVRKNE 355
+EC C G C+ C +GY A HG C DVDEC+ + C R
Sbjct: 594 DECHRVPPPC---DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR--G 648
Query: 356 NCYNTPGSYVCVCPDGF-----EETEDACV--PP 382
C N PGS+ CVCP GF EE D C PP
Sbjct: 649 ACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP 682
Score = 57.8 bits (138), Expect = 2e-08
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query: 282 ECAAEPPPCSAAQFCKN----ANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQC 337
ECA+ P + C A G + C+ C S +G + C +G+ R +G C
Sbjct: 260 ECASPLPGLRTQEVCCRGAGLAWGVHDCQLC-SERLGNSERVSAPDGPCPTGFERVNGSC 318
Query: 338 ADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF--EETEDACV 380
DVDEC+ + ++ C NT G Y CVCPDGF + + +C+
Sbjct: 319 EDVDECATGGRC---QHGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 13/87 (14%)
Query: 306 EECD--SSCVG--CTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKT---CVRKNEN 356
EEC C C G C GY + + C D++EC AE CV N
Sbjct: 1498 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV--NAR 1555
Query: 357 CYNTPGSYVCVCPDGFEETEDA--CVP 381
C NT GS+ C+C GF T C P
Sbjct: 1556 CLNTDGSFRCICRPGFAPTHQPHHCAP 1582
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 315 CTGEGPGNCKECISGYA--REHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVC 368
C PG C +GY + +C D DEC+ E C + C NT GSY C C
Sbjct: 1233 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC--EGGRCVNTVGSYHCTC 1286
Score = 36.6 bits (83), Expect = 0.041
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 12/70 (17%)
Query: 264 GECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTC--------EECDSSCVG- 314
G C G+ G+C DVDECA C + C N G YTC + SSC+
Sbjct: 305 GPCPTGFERVNGSCEDVDECAT-GGRCQHGE-CANTRGGYTCVCPDGFLLDSSRSSCISQ 362
Query: 315 -CTGEGPGNC 323
E G C
Sbjct: 363 HVISEAKGPC 372
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 277 CVDVDECAAEPPPCSAAQFCKNANGSYTC 305
C+D DECA E P C + C N GSY C
Sbjct: 1257 CIDNDECADEEPACEGGR-CVNTVGSYHC 1284
Score = 33.9 bits (76), Expect = 0.27
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 14/69 (20%)
Query: 250 ESCKTCSGLTNRDCGE--------CEVGWVLD--EGACVDVDEC---AAEPPPCSAAQFC 296
E C G TN C C G+ LD ACVD++EC A P C A+ C
Sbjct: 1498 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR-C 1556
Query: 297 KNANGSYTC 305
N +GS+ C
Sbjct: 1557 LNTDGSFRC 1565
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Query: 329 GYAREHGQCA---DVDECSL-AEKTCVRKNENCYNTPGSYVCVCPDGF 372
GY G + DVDEC L ++ C K+ C NT Y C C +G+
Sbjct: 1203 GYLAPSGDLSLRRDVDECQLFRDQVC--KSGVCVNTAPGYSCYCSNGY 1248
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 83.2 bits (204), Expect = 4e-16
Identities = 89/325 (27%), Positives = 122/325 (37%), Gaps = 77/325 (23%)
Query: 140 CQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL-----CTD---CMDGYF-----S 186
C G+ PC +GHC+ + +G C C GY+ P C D C++G F
Sbjct: 838 CSSGAP-PCGPHGHCT---NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 893
Query: 187 SLRNETHSICTVRTGLSDSYPP-----CCLSLG-------CWRGVGHAWIRGRNTHTQPG 234
L + CT G Y P CL + C G+ PG
Sbjct: 894 CLNTDGSFACTCAPG----YRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 949
Query: 235 YSSRVWIAAF---------SPAC--DESCKTCSGLTNRDCGECEVGWVLD-EGACVDVDE 282
+ + +A+ PA + C+ G + R +C+ G+ EG C DVDE
Sbjct: 950 HRAGPDLASCLDVDECRERGPALCGSQRCENSPG-SYRCVRDCDPGYHAGPEGTCDDVDE 1008
Query: 283 CAAEPPPCSAAQFCKNANGSYTC-EECDSSCVGCTGEGPGNCKECIS------------- 328
C P AQ C+N GSY C CD G G + EC +
Sbjct: 1009 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1068
Query: 329 ----------GY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETE 376
GY AR+ C DV+EC + C C N GS++CVCP+ EE +
Sbjct: 1069 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC--GAALCENVEGSFLCVCPNSPEEFD 1126
Query: 377 ---DACVPPAEAEATEGESPTQLPS 398
CVPP + T S Q P+
Sbjct: 1127 PMTGRCVPPRTSAGTFPGSQPQAPA 1151
Score = 80.9 bits (198), Expect = 2e-15
Identities = 85/307 (27%), Positives = 115/307 (37%), Gaps = 67/307 (21%)
Query: 123 TLKVCCSPG-TYGPDCLACQGGSQ-----RPCSGNGHCSGDGSRQGDGSCRCHMGYQG-P 175
+ + C PG GP C + PC G C + G C C GYQ P
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD-LGRCE---NTPGSFLCVCPAGYQAAP 664
Query: 176 LCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSL-GCWRGVGHAWIRGRNTHTQPG 234
C D CT GL C +L G +R V A RG
Sbjct: 665 HGASCQDV----------DECTQSPGLCGR--GACKNLPGSFRCVCPAGFRGSACEEDVD 712
Query: 235 YSSRVWIAAFSPACDES-----CKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPP 289
++ CD + C +G +R G C DVDECA PPP
Sbjct: 713 ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG----------APCQDVDECARSPPP 762
Query: 290 CSAAQFCKNANGSYTC------------------EECDSSCVGCTGE----GPGN--CKE 325
C+ + C+N GS+ C +EC++ + C G+ PG+ C+
Sbjct: 763 CTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENH-LACPGQECVNSPGSFQCRT 820
Query: 326 CISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEA 385
C SG+ G+C DVDECS C + +C NT GS+ C C G+ P A+
Sbjct: 821 CPSGHHLHRGRCTDVDECSSGAPPC-GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 879
Query: 386 -EATEGE 391
E EG+
Sbjct: 880 NECLEGD 886
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/313 (26%), Positives = 107/313 (34%), Gaps = 71/313 (22%)
Query: 126 VCCSPGTY-----GPDCLACQGGSQRP-CSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTD 179
+C P Y G C +Q P G G C + G C C G++G C +
Sbjct: 653 LCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACK---NLPGSFRCVCPAGFRGSACEE 709
Query: 180 -----------CMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRN 228
C G + H C PC C R GR
Sbjct: 710 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRC 768
Query: 229 THTQPGYSSRVWIAAFSP-----ACDE--SCKT---CSGLT------NRDCGECEVGWVL 272
+T+ + V F P C++ C+ C G + C C G L
Sbjct: 769 ENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 827
Query: 273 DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC---KECISG 329
G C DVDEC++ PPC C N GS+ C C +G PG C EC+ G
Sbjct: 828 HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC-SCAPGYRAPSGR-PGPCADVNECLEG 885
Query: 330 -YAREHGQ------------------------CADVDECSLAEKTCVRKNENCYNTPGSY 364
+ HG+ C DVDECS E C ++ C NT GS+
Sbjct: 886 DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLC--QSGICTNTDGSF 942
Query: 365 VCVCPDGFEETED 377
C+CP G D
Sbjct: 943 ECICPPGHRAGPD 955
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/154 (35%), Positives = 68/154 (44%), Gaps = 43/154 (27%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTC------------------ 305
C+ G+ L C+DVDEC PPPC+ + C+N+ GS+ C
Sbjct: 572 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECLDV 630
Query: 306 EECDSSCVGCTGEGPGNCKE--------CISGY-AREHG-QCADVDECSLAEKTCVRKNE 355
+EC C G C+ C +GY A HG C DVDEC+ + C R
Sbjct: 631 DECHRVPPPC---DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR--G 685
Query: 356 NCYNTPGSYVCVCPDGF-----EETEDACV--PP 382
C N PGS+ CVCP GF EE D C PP
Sbjct: 686 ACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP 719
Score = 57.8 bits (138), Expect = 2e-08
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query: 282 ECAAEPPPCSAAQFCKN----ANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQC 337
ECA+ P + C A G + C+ C S +G + C +G+ R +G C
Sbjct: 297 ECASPLPGLRTQEVCCRGAGLAWGVHDCQLC-SERLGNSERVSAPDGPCPTGFERVNGSC 355
Query: 338 ADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF--EETEDACV 380
DVDEC+ + ++ C NT G Y CVCPDGF + + +C+
Sbjct: 356 EDVDECATGGRC---QHGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 13/87 (14%)
Query: 306 EECD--SSCVG--CTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKT---CVRKNEN 356
EEC C C G C GY + + C D++EC AE CV N
Sbjct: 1535 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV--NAR 1592
Query: 357 CYNTPGSYVCVCPDGFEETEDA--CVP 381
C NT GS+ C+C GF T C P
Sbjct: 1593 CLNTDGSFRCICRPGFAPTHQPHHCAP 1619
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 315 CTGEGPGNCKECISGYA--REHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVC 368
C PG C +GY + +C D DEC+ E C + C NT GSY C C
Sbjct: 1270 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC--EGGRCVNTVGSYHCTC 1323
Score = 36.6 bits (83), Expect = 0.041
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 12/70 (17%)
Query: 264 GECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTC--------EECDSSCVG- 314
G C G+ G+C DVDECA C + C N G YTC + SSC+
Sbjct: 342 GPCPTGFERVNGSCEDVDECAT-GGRCQHGE-CANTRGGYTCVCPDGFLLDSSRSSCISQ 399
Query: 315 -CTGEGPGNC 323
E G C
Sbjct: 400 HVISEAKGPC 409
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 277 CVDVDECAAEPPPCSAAQFCKNANGSYTC 305
C+D DECA E P C + C N GSY C
Sbjct: 1294 CIDNDECADEEPACEGGR-CVNTVGSYHC 1321
Score = 33.9 bits (76), Expect = 0.27
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 14/69 (20%)
Query: 250 ESCKTCSGLTNRDCGE--------CEVGWVLD--EGACVDVDEC---AAEPPPCSAAQFC 296
E C G TN C C G+ LD ACVD++EC A P C A+ C
Sbjct: 1535 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR-C 1593
Query: 297 KNANGSYTC 305
N +GS+ C
Sbjct: 1594 LNTDGSFRC 1602
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Query: 329 GYAREHGQCA---DVDECSL-AEKTCVRKNENCYNTPGSYVCVCPDGF 372
GY G + DVDEC L ++ C K+ C NT Y C C +G+
Sbjct: 1240 GYLAPSGDLSLRRDVDECQLFRDQVC--KSGVCVNTAPGYSCYCSNGY 1285
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/295 (29%), Positives = 109/295 (36%), Gaps = 62/295 (21%)
Query: 117 EWFCVKTLKVCCSPGTYGPDCLACQGG-----SQRPCSGNGHCSGDGSRQGDGSCRCHMG 171
E FC S G+Y +C +CQ G QR C+ C + + G C G
Sbjct: 1209 ETFCTN------SEGSY--EC-SCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPG 1259
Query: 172 YQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHT 231
LC DG+ +S E C V D P CLS C G ++I H
Sbjct: 1260 EYRCLC---YDGFMAS---EDMKTC-VDVNECDLNPNICLSGTCENTKG-SFI----CHC 1307
Query: 232 QPGYSSRVWIAAFSPA--CDESCKTCS--GLTNRDCGE----CEVGWVLDEGACVDVDEC 283
GYS + + C+ C + G C GW+ D C D+DEC
Sbjct: 1308 DMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDEC 1367
Query: 284 AAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDEC 343
+ CS CKN GSY C CKE GY + C D+DEC
Sbjct: 1368 SNGTHMCSQHADCKNTMGSYRC----------------LCKE---GYTGDGFTCTDLDEC 1408
Query: 344 SLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPS 398
S C N C N PG Y C C GF VP A+ +A E LP+
Sbjct: 1409 SENLNLC--GNGQCLNAPGGYRCECDMGF-------VPSADGKACEDIDECSLPN 1454
Score = 79.3 bits (194), Expect = 6e-15
Identities = 76/259 (29%), Positives = 92/259 (35%), Gaps = 70/259 (27%)
Query: 161 QGDGSCRCHMGYQGPL----CTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCW 216
+G C C MGY G CTD + + H++CT G S+ C
Sbjct: 1300 KGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAG---SFKCSC------ 1350
Query: 217 RGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGE--------CEV 268
PG+ C CS + DC C+
Sbjct: 1351 ---------------SPGWIGDGIKCTDLDECSNGTHMCS--QHADCKNTMGSYRCLCKE 1393
Query: 269 GWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCV----GCTGEGPGNCK 324
G+ D C D+DEC+ C Q C NA G Y CE CD V G E C
Sbjct: 1394 GYTGDGFTCTDLDECSENLNLCGNGQ-CLNAPGGYRCE-CDMGFVPSADGKACEDIDECS 1451
Query: 325 -------------------ECISGYA--REHGQCADVDECSLAEKTCVRKNENCYNTPGS 363
EC GY R G C DV+EC L TC+ + NC NTPGS
Sbjct: 1452 LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCI--SGNCVNTPGS 1508
Query: 364 YVCVCPDGFE--ETEDACV 380
Y+C CP FE T CV
Sbjct: 1509 YICDCPPDFELNPTRVGCV 1527
Score = 72.0 bits (175), Expect = 9e-13
Identities = 75/292 (25%), Positives = 102/292 (34%), Gaps = 47/292 (16%)
Query: 119 FCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCT 178
FC + C G P C GS+ N C GS D C C GY G C
Sbjct: 93 FCSRPNMCTCPSGQIAPSC-----GSRSIQHCNIRCMNGGSCSDD-HCLCQKGYIGTHCG 146
Query: 179 D--CMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLG-CWRGVGHAWIRGRNTHTQPGY 235
C G + R + C G + G C+ + + +G+ +
Sbjct: 147 QPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIV--C 204
Query: 236 SSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWV--LDEGACVDVDECAAEPPPCSAA 293
+ + A A C+ C + C G++ + GAC DVDEC A P C
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPH----PCRRGFIPNIRTGACQDVDECQAIPGLCQGG 260
Query: 294 QFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH--GQCADVDECSLAEKTCV 351
C N GS+ C+ C +G+ +C D+DECS C
Sbjct: 261 N-CINTVGSFECK-------------------CPAGHKLNEVSQKCEDIDECSTIPGIC- 299
Query: 352 RKNENCYNTPGSYVCVCPDGFEETEDA--CVPP----AEAEATEGESPTQLP 397
+ C NT SY C CP GF + D C+ T G QLP
Sbjct: 300 -EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLP 350
Score = 70.9 bits (172), Expect = 2e-12
Identities = 44/116 (37%), Positives = 54/116 (46%), Gaps = 27/116 (23%)
Query: 265 ECEVGWVLD-EGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
EC G+ LD G C+DVDEC E PC+ + C N GSYTC+
Sbjct: 475 ECNKGFQLDLRGECIDVDEC--EKNPCAGGE-CINNQGSYTCQ----------------- 514
Query: 324 KECISGYARE--HGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETED 377
C +GY +C D+DEC + C N C NT GS+ CVC GF T D
Sbjct: 515 --CRAGYQSTLTRTECRDIDECLQNGRIC--NNGRCINTDGSFHCVCNAGFHVTRD 566
Score = 69.7 bits (169), Expect = 4e-12
Identities = 82/324 (25%), Positives = 116/324 (35%), Gaps = 78/324 (24%)
Query: 121 VKTLKVCCSPGTY----GPDCLACQGGSQRP--CSGNGHCSGDGSRQGDGSCRCHMGYQG 174
+ T C PG G C+ +P C NG C + +G +C C+ G+
Sbjct: 2269 IGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE-NGRCL---NTRGSYTCECNDGFTA 2324
Query: 175 -PLCTDCMDGYFSSLRNET-HSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQ 232
P +C+D E ++C + S + P S C G G W G +
Sbjct: 2325 SPNQDECLDNREGYCFTEVLQNMCQIG---SSNRNPVTKSECCCDG-GRGW--GPHCEIC 2378
Query: 233 PGYSSRVWIAAFSPACD------------ESCKTCSGLT-NRDCGE--------CEVGWV 271
P + AF C + CK + N +C C+ G+
Sbjct: 2379 PFQGT----VAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYT 2434
Query: 272 LD--EGACVDVDECAAEPPPCSAAQFCKNANGSYTCE----------------------- 306
D +CVD++EC P PC+ CKN GSY C
Sbjct: 2435 PDITGTSCVDLNECNQAPKPCNF--ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATK 2492
Query: 307 --ECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSY 364
C CV G G +C G+ + H C D +EC+ C K C NTPGS+
Sbjct: 2493 QHNCQFLCVNTIG---GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKG-ICQNTPGSF 2548
Query: 365 VCVCPDGF--EETEDACVPPAEAE 386
C C GF ++T +C E E
Sbjct: 2549 TCECQRGFSLDQTGSSCEDVDECE 2572
Score = 68.9 bits (167), Expect = 8e-12
Identities = 71/271 (26%), Positives = 94/271 (34%), Gaps = 76/271 (28%)
Query: 140 CQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSI---- 195
CQ G C N C G C C GY+ C D RNE I
Sbjct: 1812 CQNGPV--CQRNAECINTA---GSYRCDCKPGYRFTSTGQCND------RNECQEIPNIC 1860
Query: 196 -------------CTVRTGL--SDSYPPC-----CLSLGCWRGVGHAWIRGRNTHTQPGY 235
C TG +D C C C G I N G+
Sbjct: 1861 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGF 1920
Query: 236 SSRVWIAAFSPACDESCKTCSG----LTNRDC--------GECEVGWVL--DEGACVDVD 281
I + + C + + SG N C +C G+ + D CVD++
Sbjct: 1921 -----ILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDIN 1975
Query: 282 ECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVD 341
EC EP C A C+N +GSY C C GY+ ++ +C D+D
Sbjct: 1976 ECLLEPRKC-APGTCQNLDGSYRC-------------------ICPPGYSLQNEKCEDID 2015
Query: 342 ECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
EC + C C NT GS+ C+CP+GF
Sbjct: 2016 ECVEEPEICAL--GTCSNTEGSFKCLCPEGF 2044
Score = 68.2 bits (165), Expect = 1e-11
Identities = 47/154 (30%), Positives = 60/154 (38%), Gaps = 33/154 (21%)
Query: 265 ECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSY--TCEE--------------- 307
EC G++L CVD DEC+ P + CKN G + TCEE
Sbjct: 2152 ECPFGYILAGNECVDTDECSVGNPCGNGT--CKNVIGGFECTCEEGFEPGPMMTCEDINE 2209
Query: 308 -------CDSSCVGCTGEGPGNCKECISGYA--REHGQCADVDECSLAEKTCVRKNENCY 358
C CV G CK C GY + C D DEC + C K C
Sbjct: 2210 CAQNPLLCAFRCVNTYGSY--ECK-CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECK 2266
Query: 359 NTPGSYVCVCPDGFEETED--ACVPPAEAEATEG 390
N G+Y+C+C G++ D CV E + G
Sbjct: 2267 NLIGTYMCICGPGYQRRPDGEGCVDENECQTKPG 2300
Score = 66.2 bits (160), Expect = 5e-11
Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 26/132 (19%)
Query: 265 ECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE--------ECDSSCV--- 313
+C G+ +C+D +EC ++ C + C+N GS+TCE + SSC
Sbjct: 2510 KCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVD 2569
Query: 314 ----------GCTGEGPGNCKECISGYAREH--GQCADVDECSLAEKTCVRKNENCYNTP 361
GC G C GY + + QC D +EC A + +C+NT
Sbjct: 2570 ECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH---ICGGASCHNTL 2626
Query: 362 GSYVCVCPDGFE 373
GSY C+CP GF+
Sbjct: 2627 GSYKCMCPAGFQ 2638
Score = 65.5 bits (158), Expect = 8e-11
Identities = 87/347 (25%), Positives = 117/347 (33%), Gaps = 90/347 (25%)
Query: 127 CCSP--GTYGPDCLACQGGSQRPCSGNGHCSGDGSR----------------------QG 162
CCS +G C CQ P G G+ G++ +G
Sbjct: 875 CCSSLGAAWGSPCTLCQVD---PICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRG 931
Query: 163 DGSCRCHMGYQ----GPLCTDC-MDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGC-W 216
C+C G G +C D ++ F +E CT+ CC S+G W
Sbjct: 932 SFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEE---CTLPIAGRHRMDACCCSVGAAW 988
Query: 217 RGVGHAWIRGRNTHTQ-------PGYSSRVWIAAFSPACDE--SCKTCSGL-TNRDCGE- 265
RNT PG++++ I P + CK L T+ C
Sbjct: 989 GTEECEECPMRNTPEYEELCPRGPGFATKE-ITNGKPFFKDINECKMIPSLCTHGKCRNT 1047
Query: 266 -------CEVGWVLD--EGACVDVDECAAEPPPCSAAQFCKNANGSYTC----------- 305
C+ G+ LD E C D+DEC P C Q C N G + C
Sbjct: 1048 IGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ-CVNTPGDFECKCDEGYESGFM 1106
Query: 306 --------EECDSSCVGCTG------EGPGNCKECISGY--AREHGQCADVDECSLAEKT 349
+EC + C G EG C EC G+ + C D++EC L+
Sbjct: 1107 MMKNCMDIDECQRDPLLCRGGVCHNTEGSYRC-ECPPGHQLSPNISACIDINECELSAHL 1165
Query: 350 CVRKNENCYNTPGSYVCVCPDGFEETEDA--CVPPAEAEATEGESPT 394
C N C N G Y C C G+ T D CV E G T
Sbjct: 1166 C--PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCET 1210
Score = 63.5 bits (153), Expect = 3e-10
Identities = 48/139 (34%), Positives = 61/139 (43%), Gaps = 26/139 (18%)
Query: 274 EGACVDVDECAAEPPPCSAAQFCKNANGSYTCE----------ECDSSCVGCTGE--GPG 321
+ + VD+DEC EP C Q C N +GSY CE EC + G G G
Sbjct: 2122 DDSAVDMDECK-EPDVCKHGQ-CINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG 2179
Query: 322 NCKECISGY--AREHG-------QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
CK I G+ E G C D++EC+ C + C NT GSY C CP G+
Sbjct: 2180 TCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR---CVNTYGSYECKCPVGY 2236
Query: 373 EETEDACVPPAEAEATEGE 391
ED + E E EG+
Sbjct: 2237 VLREDRRMCKDEDECEEGK 2255
Score = 60.5 bits (145), Expect = 3e-09
Identities = 44/127 (34%), Positives = 53/127 (41%), Gaps = 28/127 (22%)
Query: 265 ECEVGWVL--DEGACVDVDECAAEPPPCSAAQF-CKNANGSYTCEECDSSCVGCTGEGPG 321
+C VG+VL D C D DEC C+ Q CKN G+Y C
Sbjct: 2231 KCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI--------------- 2275
Query: 322 NCKECISGYARE-HGQ-CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF--EETED 377
C GY R G+ C D +EC C +N C NT GSY C C DGF +D
Sbjct: 2276 ----CGPGYQRRPDGEGCVDENECQTKPGIC--ENGRCLNTRGSYTCECNDGFTASPNQD 2329
Query: 378 ACVPPAE 384
C+ E
Sbjct: 2330 ECLDNRE 2336
Score = 59.7 bits (143), Expect = 5e-09
Identities = 68/260 (26%), Positives = 89/260 (34%), Gaps = 66/260 (25%)
Query: 123 TLKVCCSPG-TYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCH------MGYQGP 175
+ K C PG D C+ ++ C G C DGS RC +G G
Sbjct: 593 SFKCICKPGFQLASDGRYCKDINE--CETPGICMNGRCVNTDGSYRCECFPGLAVGLDGR 650
Query: 176 LCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGY 235
+C D TH T G RG + G T
Sbjct: 651 VCVD------------THMRSTCYGGYK-------------RGQCIKPLFGAVT------ 679
Query: 236 SSRVWIAAFSPACDESCKTCSGLTNRDCGE-CEVGWVLDEGACVDVDECAAEPPPCSAAQ 294
S A+ A E C+ C + + C G + D++ECA +P C
Sbjct: 680 KSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS-DINECALDPDICPNG- 737
Query: 295 FCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHG--QCADVDECSLAEKTCVR 352
C+N G+Y C C SGY + C D++EC L C
Sbjct: 738 ICENLRGTYKCI-------------------CNSGYEVDSTGKNCVDINECVLNSLLC-- 776
Query: 353 KNENCYNTPGSYVCVCPDGF 372
N C NTPGS+VC CP GF
Sbjct: 777 DNGQCRNTPGSFVCTCPKGF 796
Score = 58.5 bits (140), Expect = 1e-08
Identities = 46/156 (29%), Positives = 63/156 (40%), Gaps = 28/156 (17%)
Query: 246 PACDESCKTCSGLTNRDCGECEVGW-VLDEGACVDVDECAAEPPPCSAAQFCKNANGSYT 304
P C + + + + C +C+ G+ G C D +EC P CS Q C + GS+
Sbjct: 1816 PVCQRNAECINTAGSYRC-DCKPGYRFTSTGQCNDRNECQEIPNICSHGQ-CIDTVGSFY 1873
Query: 305 C------------------EECDSSCVG---CTGE-GPGNCKECISGYAREHGQ-CADVD 341
C EC+ G C G NC+ C G+ H C DVD
Sbjct: 1874 CLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCR-CNHGFILSHNNDCIDVD 1932
Query: 342 ECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETED 377
EC+ R N C NT GS+ C C +G+E D
Sbjct: 1933 ECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPD 1967
Score = 57.8 bits (138), Expect = 2e-08
Identities = 63/280 (22%), Positives = 96/280 (34%), Gaps = 71/280 (25%)
Query: 129 SPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGY----QGPLCTDCMDGY 184
+P G C+ +Q P N C + +G C C GY G C D +
Sbjct: 2434 TPDITGTSCVDLNECNQAPKPCNFICK---NTEGSYQCSCPKGYILQEDGRSCKDLDE-- 2488
Query: 185 FSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAF 244
++ ++ +C G G PG++
Sbjct: 2489 CATKQHNCQFLCVNTIG------------------------GFTCKCPPGFTQHHTSCID 2524
Query: 245 SPACDESCKTCS--GLTNRDCG----ECEVGWVLDE--GACVDVDECAAEPPPCSAAQFC 296
+ C C G+ G EC+ G+ LD+ +C DVDEC C
Sbjct: 2525 NNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNH---RCQHGC 2581
Query: 297 KNANGSYTCE------------EC--DSSCVGCTGEGPGNCKE--------CISGYAREH 334
+N G Y C +C ++ C+ G +C C +G+ E
Sbjct: 2582 QNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQ 2641
Query: 335 --GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
G C D++EC A+ C + C NT G Y+C CP G+
Sbjct: 2642 FSGGCQDINECGSAQAPC---SYGCSNTEGGYLCGCPPGY 2678
Score = 56.6 bits (135), Expect = 4e-08
Identities = 43/144 (29%), Positives = 58/144 (40%), Gaps = 35/144 (24%)
Query: 263 CGECEVGWVLD--EGACVDVDECAAEPPPCSAAQFCKNANGSYTCE-------------- 306
CG G+V+D G VD+DEC P C C N GS+ CE
Sbjct: 1748 CGSQRPGFVIDIYTGLPVDIDECREIPGVCENG-VCINMVGSFRCECPVGFFYNDKLLVC 1806
Query: 307 ----EC--------DSSCVGCTGEGPGNCKECISGYA-REHGQCADVDECSLAEKTCVRK 353
EC ++ C+ G +CK GY GQC D +EC C
Sbjct: 1807 EDIDECQNGPVCQRNAECINTAGSYRCDCK---PGYRFTSTGQCNDRNECQEIPNIC--S 1861
Query: 354 NENCYNTPGSYVCVCPDGFEETED 377
+ C +T GS+ C+C GF+ +D
Sbjct: 1862 HGQCIDTVGSFYCLCHTGFKTNDD 1885
Score = 55.5 bits (132), Expect = 9e-08
Identities = 47/154 (30%), Positives = 59/154 (38%), Gaps = 53/154 (34%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE----------------- 306
C G++ D C D+DEC E PC CKN+ GS+ CE
Sbjct: 792 CPKGFIYKPDLKTCEDIDEC--ESSPCING-VCKNSPGSFICECSSESTLDPTKTICIET 848
Query: 307 ------------ECD---------SSCVGCTGEGPGN----CKE---CISGYAREHG-QC 337
C+ S C G G+ C+ C GY+R G QC
Sbjct: 849 IKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQC 908
Query: 338 ADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG 371
D+DEC + C KN C NT GS+ C CP G
Sbjct: 909 EDIDECEVFPGVC--KNGLCVNTRGSFKCQCPSG 940
Score = 51.6 bits (122), Expect = 1e-06
Identities = 62/234 (26%), Positives = 83/234 (35%), Gaps = 67/234 (28%)
Query: 175 PLCT-DCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQP 233
P+C C DG+ S ++CT +G P C S R + H IR N +
Sbjct: 83 PICRHSCGDGFCSR-----PNMCTCPSG---QIAPSCGS----RSIQHCNIRCMNGGS-- 128
Query: 234 GYSSRVWIAAFSPACDESCKTCSGLTNRDCGE--CEVGWVLDEGACVDVDECAAE----P 287
D+ C G CG+ CE G L+ G CV + CA
Sbjct: 129 -------------CSDDHCLCQKGYIGTHCGQPVCESG-CLNGGRCVAPNRCACTYGFTG 174
Query: 288 PPCS------------AAQFCKNANGSYTCEECDSSCVGCTGEGPGN-CKECISGYAREH 334
P C + Q C+ C + + C G G+ C+ C A+ H
Sbjct: 175 PQCERDYRTGPCFTVISNQMCQGQLSGIVCTK--TLCCATVGRAWGHPCEMCP---AQPH 229
Query: 335 ------------GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETE 376
G C DVDEC C + NC NT GS+ C CP G + E
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLC--QGGNCINTVGSFECKCPAGHKLNE 281
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/186 (26%), Positives = 62/186 (33%), Gaps = 59/186 (31%)
Query: 254 TCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTC-------- 305
TC L C G+ L C D+DEC EP C A C N GS+ C
Sbjct: 1988 TCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLCPEGFSL 2046
Query: 306 ---------------------EECDS----------SCVGCTGEGPGN-CKEC------- 326
+C S C GEG G+ C+ C
Sbjct: 2047 SSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEA 2106
Query: 327 ---ISGYAR-----EHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA 378
I Y D+DEC ++ V K+ C NT GSY C CP G+ +
Sbjct: 2107 FRQICPYGSGIIVGPDDSAVDMDEC---KEPDVCKHGQCINTDGSYRCECPFGYILAGNE 2163
Query: 379 CVPPAE 384
CV E
Sbjct: 2164 CVDTDE 2169
Score = 49.3 bits (116), Expect = 6e-06
Identities = 64/279 (22%), Positives = 95/279 (34%), Gaps = 51/279 (18%)
Query: 136 DCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL----CTD----------CM 181
+C+ + PC+G G C + QG +C+C GYQ L C D C
Sbjct: 487 ECIDVDECEKNPCAG-GECINN---QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN 542
Query: 182 DGYFSSLRNETHSICTV-----RTGLS-DSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGY 235
+G + H +C R G + + C + C G+ +PG+
Sbjct: 543 NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGF 602
Query: 236 SSRVWIAAFSPACDE--SCKTCSGLTNRDCG--------ECEVGWV--LDEGACVDVDEC 283
+A+ C + C+T N C EC G LD CVD
Sbjct: 603 Q----LASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMR 658
Query: 284 AAEPPPCSAAQFCKNANGSYTCEEC---------DSSCVGCTGEGPGNCKECISGYAREH 334
+ Q K G+ T EC C C + + S
Sbjct: 659 STCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMT 718
Query: 335 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
+D++EC+L C N C N G+Y C+C G+E
Sbjct: 719 SAGSDINECALDPDIC--PNGICENLRGTYKCICNSGYE 755
Score = 45.1 bits (105), Expect = 1e-04
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 25/96 (26%)
Query: 279 DVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQ-- 336
D+DEC P C + C N GS+ C C +GY
Sbjct: 1606 DIDECQELPGLCQGGK-CINTFGSFQCR-------------------CPTGYYLNEDTRV 1645
Query: 337 CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C DV+EC E + CYNT G+Y C+CP +
Sbjct: 1646 CDDVNEC---ETPGICGPGTCYNTVGNYTCICPPDY 1678
Score = 43.9 bits (102), Expect = 3e-04
Identities = 79/336 (23%), Positives = 107/336 (31%), Gaps = 113/336 (33%)
Query: 123 TLKVCCSPGTYGP-----DCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLC 177
+ K CSPG G D C G+ CS + C + G C C GY G
Sbjct: 1345 SFKCSCSPGWIGDGIKCTDLDECSNGTHM-CSQHADCK---NTMGSYRCLCKEGYTG--- 1397
Query: 178 TDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSS 237
DG+ + +E C+ L C + C G G G+
Sbjct: 1398 ----DGFTCTDLDE----CSENLNL-------CGNGQCLNAPG-----GYRCECDMGFVP 1437
Query: 238 RVWIAAFSPACDE--SCK--------TCSGLTNRDCGECEVGWVLDE--GACVDVDECAA 285
+A AC++ C TC L ECE+G+ LD G C DV+EC
Sbjct: 1438 ----SADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECL- 1492
Query: 286 EPPPCSAAQFCKNA--------------------------------------NGSYTCEE 307
+P C + C N NG C
Sbjct: 1493 DPTTCISGN-CVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSN 1551
Query: 308 ------CDSSCVGCTGEGPGN-CKECISGYAREH------GQ----------CADVDECS 344
+SC G+ G C+ C + E+ G+ D+DEC
Sbjct: 1552 EIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQ 1611
Query: 345 LAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACV 380
C + C NT GS+ C CP G+ ED V
Sbjct: 1612 ELPGLC--QGGKCINTFGSFQCRCPTGYYLNEDTRV 1645
Score = 36.2 bits (82), Expect = 0.054
Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 13/73 (17%)
Query: 305 CEEC-----DSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYN 359
CE+C D C + PG + +G D+DEC C +N C N
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP------VDIDECREIPGVC--ENGVCIN 1784
Query: 360 TPGSYVCVCPDGF 372
GS+ C CP GF
Sbjct: 1785 MVGSFRCECPVGF 1797
Score = 32.0 bits (71), Expect = 1.0
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
C G+ L+E C DV+EC E P C N G+YTC C + G NC
Sbjct: 1633 CPTGYYLNEDTRVCDDVNEC--ETPGICGPGTCYNTVGNYTC-ICPPDYMQV--NGGNNC 1687
Query: 324 KE-----CISGYAREHGQCADVDECSLAEKTC 350
+ C Y ++ C ++ +K C
Sbjct: 1688 MDMRRSLCYRNYYADNQTCDGELLFNMTKKMC 1719
Score = 31.2 bits (69), Expect = 1.7
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 3/47 (6%)
Query: 341 DECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE-ETEDACVPPAEAE 386
D C L C +N C TPGS C C GF+ + C+ E E
Sbjct: 451 DYCQLVRYLC--QNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECE 495
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 80.9 bits (198), Expect = 2e-15
Identities = 78/291 (26%), Positives = 104/291 (35%), Gaps = 57/291 (19%)
Query: 119 FCVKTL--KVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL 176
+C +T+ + CC G +GPDC C GG PC G G+CS DG QG+G+C C Y+G
Sbjct: 710 YCNQTIMEQGCCK-GFFGPDCTQCPGGFSNPCYGKGNCS-DGI-QGNGACLCFPDYKGIA 766
Query: 177 CTDCMDGYFSSLRNE-----THSICTVRTG----------------------LSDSYPP- 208
C C + + + H +C R G + D P
Sbjct: 767 CHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTG 826
Query: 209 ----CCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSP---ACDESCKTCSGLTNR 261
C L C G A R + G+S P C E+ + G
Sbjct: 827 LAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGT 886
Query: 262 DCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPG 321
C GW D CV +DEC + G +T D+ C G G
Sbjct: 887 HHCTCHKGWSGDGRVCVAIDECELD-----------MRGGCHT----DALC-SYVGPGQS 930
Query: 322 NCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C C G+A + QC+ +D C C G VC CP GF
Sbjct: 931 RC-TCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
Score = 73.9 bits (180), Expect = 2e-13
Identities = 74/288 (25%), Positives = 97/288 (33%), Gaps = 62/288 (21%)
Query: 120 CVKTL-KVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCT 178
CV T K C PG YG +C AC GG PCS G C DG G G C C G+ G C
Sbjct: 1950 CVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCM-DG-MSGSGQCLCRSGFAGTACE 2007
Query: 179 DCMDGYF----SSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPG 234
C G F + R H C G S S C W G P
Sbjct: 2008 LCAPGAFGPHCQACRCTVHGRCDEGLGGSGS----CFCDEGWTG--------------PR 2049
Query: 235 YSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQ 294
++ P C C + + EC +G+ D C D C CS
Sbjct: 2050 CEVQL---ELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHA 2106
Query: 295 FCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKN 354
C TC C+ Y + C + C+ + ++
Sbjct: 2107 NCSQVGTMVTC-------------------TCLPDYEGDGWSCRARNPCTDGHRGGCSEH 2147
Query: 355 ENCYNTP-GSYVCVCPDGF--------EETE---DACV---PPAEAEA 387
NC +T + C C G+ EE+E D C+ PP ++A
Sbjct: 2148 ANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDA 2195
Score = 72.4 bits (176), Expect = 7e-13
Identities = 70/295 (23%), Positives = 103/295 (34%), Gaps = 53/295 (17%)
Query: 88 FECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVC-CSPGTYGPDCLACQGGSQR 146
F C Q + Q+ ++ + + + C K ++V C PG +G C C GG
Sbjct: 1279 FRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGG 1338
Query: 147 PCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYF----SSLRNETHSICTVRTGL 202
CSG+G C G G C CH G+ G C C G + + + + H +C + GL
Sbjct: 1339 VCSGHGQC--QDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLC--QEGL 1394
Query: 203 SDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRD 262
C ++G W+G+ R SP C C +
Sbjct: 1395 QGD-GSCVCNVG-WQGL------------------RCDQKITSPQCPRKCDPNANCVQDS 1434
Query: 263 CG----ECEVGWVLDEGACVDVDECAAEPPPCSAAQFC-KNANGSYTCEECDSSCVGCTG 317
G C G+ + C +VD CA CS C K A G TC
Sbjct: 1435 AGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTC------------ 1482
Query: 318 EGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C GY + C +++ C + C E P C C +G+
Sbjct: 1483 -------TCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY 1530
Score = 68.2 bits (165), Expect = 1e-11
Identities = 64/259 (24%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 125 KVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGY 184
K CC PG +G C C GG++ PC+G+G C R +G+C C ++G C +C D
Sbjct: 98 KACC-PGYWGSRCHECPGGAETPCNGHGTCLDGMDR--NGTCVCQENFRGSACQECQD-- 152
Query: 185 FSSLRNETHSICTVRTGLSDSYPPCCLSL-GCWRGVGHAWIRGRNTHTQPGYSSRVWIAA 243
+ + P C S+ C GV + H G S + A
Sbjct: 153 ------------------PNRFGPDCQSVCSCVHGVCN--------HGPRGDGSCLCFAG 186
Query: 244 FS-PACDESCKTCSGL---TNRDCG------ECEVGWVLDEGACVDVDECAAEPPPCSAA 293
++ P CD+ C L N C C G+ C + C P PCS
Sbjct: 187 YTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC--WPSPCSLL 244
Query: 294 QFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRK 353
C + +G C C Y + C D C+ C
Sbjct: 245 AQC-----------------SVSPKGQAQC-HCPENYHGDGMVCLPKDPCTDNLGGCPSN 286
Query: 354 NENC-YNTPGSYVCVCPDG 371
+ C Y PG C C G
Sbjct: 287 STLCVYQKPGQAFCTCRPG 305
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 79.3 bits (194), Expect = 6e-15
Identities = 81/288 (28%), Positives = 110/288 (38%), Gaps = 61/288 (21%)
Query: 121 VKTLKVCCSPG-TYGPDCLACQGGSQ-RPCSG---NGHCSGDGSRQGDGSCRCHMGYQGP 175
+ T C PG PD C ++ R G NG C + G C C+ G+Q
Sbjct: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCV---NIIGSYRCECNEGFQSS 2372
Query: 176 LC-TDCMDGYFSSLRNET-HSICTVRTGLSD--SYPPCCLSLGCWRGVGHAWIRGRNTHT 231
T+C+D E +IC + + + + CC G RG GH
Sbjct: 2373 SSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGG--RGWGHQC----ELCP 2426
Query: 232 QPGYSSRVWIAAFSPACD------ESCKTCSGL-TNRDCGE--------CEVGWVLDEG- 275
PG + I P + CK L TN C C+VG+ D
Sbjct: 2427 LPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISG 2486
Query: 276 -ACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYA-RE 333
+C+D+DEC+ P PC+ CKN GSY C C GY +E
Sbjct: 2487 TSCIDLDECSQSPKPCN--YICKNTEGSYQCS-------------------CPRGYVLQE 2525
Query: 334 HGQ-CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACV 380
G+ C D+DEC + C C NT G + C CP GF + AC+
Sbjct: 2526 DGKTCKDLDECQTKQHNC---QFLCVNTLGGFTCKCPPGFTQHHTACI 2570
Score = 78.2 bits (191), Expect = 1e-14
Identities = 73/263 (27%), Positives = 99/263 (37%), Gaps = 73/263 (27%)
Query: 127 CCSPGTYGPDCLACQGG-----SQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCT-DC 180
C + GT D CQ G +P NG C G G C C G+ GP C D
Sbjct: 153 CMNGGTCADDHCQCQKGYIGTYCGQPVCENG-CQNGGRCIGPNRCACVYGFTGPQCERDY 211
Query: 181 MDG-YFSSLRNETHSICTVR-TGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSR 238
G F+ + N+ +C + TG+ + CC ++G R GH
Sbjct: 212 RTGPCFTQVNNQ---MCQGQLTGIVCTKTLCCATIG--RAWGHP---------------- 250
Query: 239 VWIAAFSPACDESCKTCSGLTNRDCGECEVGWV--LDEGACVDVDECAAEPPPCSAAQFC 296
C+ C C G++ + GAC DVDEC A P C C
Sbjct: 251 -------------CEMCPAQPQ----PCRRGFIPNIRTGACQDVDECQAIPGICQGGN-C 292
Query: 297 KNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHG--QCADVDECSLAEKTCVRKN 354
N GS+ C C +G+ + +C D+DECS+ C +
Sbjct: 293 INTVGSFECR-------------------CPAGHKQSETTQKCEDIDECSIIPGIC--ET 331
Query: 355 ENCYNTPGSYVCVCPDGFEETED 377
C NT GSY CVCP G+ + D
Sbjct: 332 GECSNTVGSYFCVCPRGYVTSTD 354
Score = 73.6 bits (179), Expect = 3e-13
Identities = 47/140 (33%), Positives = 64/140 (45%), Gaps = 28/140 (20%)
Query: 265 ECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE------------------ 306
+C G+ AC+D +EC ++P C A C+N GS++CE
Sbjct: 2557 KCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVD 2616
Query: 307 ECDSS--CV-GCTGEGPGNCKECISGYAREH--GQCADVDECSLAEKTCVRKNENCYNTP 361
ECD + C GC G C GY + + QC D +ECS C + +CYNT
Sbjct: 2617 ECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECS-NPNAC--GSASCYNTL 2673
Query: 362 GSYVCVCPDG--FEETEDAC 379
GSY C CP G F++ AC
Sbjct: 2674 GSYKCACPSGFSFDQFSSAC 2693
Score = 73.2 bits (178), Expect = 4e-13
Identities = 65/218 (29%), Positives = 87/218 (39%), Gaps = 40/218 (18%)
Query: 215 CWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDES-CKTCSGLTNRDCGECEVGWVLD 273
C RG G A RG +P Y AF C C+ G + C C G+ LD
Sbjct: 1052 CPRGAGFA-NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIG--SFKC-RCNSGFALD 1107
Query: 274 --EGACVDVDECAAEPPPCSAAQFCKNANGSYTCE-------------------ECDSSC 312
E C D+DEC P C + C N GS+ CE EC+ +
Sbjct: 1108 MEERNCTDIDECRISPDLCGSG-ICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNP 1166
Query: 313 VGCTG------EGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSY 364
+ C G EG C +C G+ + C D++ECSL++ C +N C N G+Y
Sbjct: 1167 LLCRGGTCVNTEGSFQC-DCPLGHELSPSREDCVDINECSLSDNLC--RNGKCVNMIGTY 1223
Query: 365 VCVCPDGFEETED--ACVPPAEAEATEGESPTQLPSRE 400
C C G++ T D C E G TQ + E
Sbjct: 1224 QCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSE 1261
Score = 72.4 bits (176), Expect = 7e-13
Identities = 76/309 (24%), Positives = 106/309 (34%), Gaps = 93/309 (30%)
Query: 121 VKTLKVCCSPGTYG-PD---------CLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHM 170
+ T + C+PG PD C+ GG C+ + +G C C
Sbjct: 1220 IGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNS---------EGSYECSCSE 1270
Query: 171 GY----------------------QGPLCTD--------CMDGYFSSLRNETHSICTVRT 200
GY G CT+ C DG+ +S+ +T +
Sbjct: 1271 GYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKT----CIDV 1326
Query: 201 GLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPA---------CD-- 249
D C+ C G ++I H Q GYS + + CD
Sbjct: 1327 NECDLNSNICMFGECENTKG-SFI----CHCQLGYSVKKGTTGCTDVDECEIGAHNCDMH 1381
Query: 250 ESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECD 309
SC G C E GW+ + C+D+DEC+ CS C N GSY C
Sbjct: 1382 ASCLNIPGSFKCSCRE---GWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC---- 1434
Query: 310 SSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCP 369
C G+ + C+DVDEC AE + +N C N PG+Y C C
Sbjct: 1435 ---------------ACSEGFTGDGFTCSDVDEC--AENINLCENGQCLNVPGAYRCECE 1477
Query: 370 DGFEETEDA 378
GF D+
Sbjct: 1478 MGFTPASDS 1486
Score = 68.6 bits (166), Expect = 1e-11
Identities = 69/261 (26%), Positives = 99/261 (37%), Gaps = 50/261 (19%)
Query: 148 CSGNGHCSGDGSRQGDGSCRCHMGYQ-GPLCTDCMDGYFSSLRNETHSICTVRTGLSDSY 206
C G + +GS Q C C +G++ P DC+D SL + ++C R G
Sbjct: 1169 CRGGTCVNTEGSFQ----CDCPLGHELSPSREDCVDINECSLSD---NLC--RNG----- 1214
Query: 207 PPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGEC 266
C +G ++ + + T + G + + CD C G C E
Sbjct: 1215 -KCVNMIGTYQCSCNPGYQA--TPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSE- 1270
Query: 267 EVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTC------------------E 306
G+ L D +C D+DEC P C Q C N G Y C
Sbjct: 1271 --GYALMPDGRSCADIDECENNPDICDGGQ-CTNIPGEYRCLCYDGFMASMDMKTCIDVN 1327
Query: 307 ECDSSCVGCTGEGPGNCK-----ECISGYAREHGQ--CADVDECSLAEKTCVRKNENCYN 359
ECD + C N K C GY+ + G C DVDEC + C + +C N
Sbjct: 1328 ECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC-DMHASCLN 1386
Query: 360 TPGSYVCVCPDGFEETEDACV 380
PGS+ C C +G+ C+
Sbjct: 1387 IPGSFKCSCREGWIGNGIKCI 1407
Score = 67.8 bits (164), Expect = 2e-11
Identities = 46/129 (35%), Positives = 58/129 (44%), Gaps = 29/129 (22%)
Query: 265 ECEVGWVLD-EGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
EC +G+ D G C+DVDEC + P C+ C N GSY C+
Sbjct: 520 ECNMGYKQDANGDCIDVDECTSNP--CTNGD-CVNTPGSYYCK----------------- 559
Query: 324 KECISGYAREHGQ--CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA--C 379
C +G+ R + C D+DEC C KN C NT GS+ C+C GFE T D C
Sbjct: 560 --CHAGFQRTPTKQACIDIDECIQNGVLC--KNGRCVNTDGSFQCICNAGFELTTDGKNC 615
Query: 380 VPPAEAEAT 388
V E T
Sbjct: 616 VDHDECTTT 624
Score = 66.2 bits (160), Expect = 5e-11
Identities = 76/299 (25%), Positives = 108/299 (36%), Gaps = 62/299 (20%)
Query: 120 CVKT---LKVCCSPG----TYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGY 172
CV T + C+ G T G +C+ + NG C + G C C G+
Sbjct: 591 CVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINE---DGSFKCICKPGF 647
Query: 173 ----QGPLCTD---------CMDGYFSSLRNETHSICTVRTGLSDSYPPCC---LSLGCW 216
G CTD CM+G+ + C + C + C+
Sbjct: 648 VLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCY 707
Query: 217 RGVGHAWIRGRNTHTQPGYSSRVWIAAFSP--ACDESCKTCSGLTNRDC-GECEVG-WVL 272
G+ +G PG ++ +P E C+ C + + G C G +
Sbjct: 708 GGIK----KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGIT 763
Query: 273 DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAR 332
+G D++ECA +P C A C+N GSY C C SGY
Sbjct: 764 VDGR--DINECALDPDIC-ANGICENLRGSYRCN-------------------CNSGYEP 801
Query: 333 EHG--QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG--FEETEDACVPPAEAEA 387
+ C D+DEC + C N C NTPGSY C CP G F + C E E+
Sbjct: 802 DASGRNCIDIDECLVNRLLC--DNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECES 858
Score = 61.6 bits (148), Expect = 1e-09
Identities = 66/249 (26%), Positives = 88/249 (35%), Gaps = 59/249 (23%)
Query: 146 RPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCT----------DCMDGYFS-SLRNETHS 194
R C C G G+C +G +C +CMD S R+ +
Sbjct: 1688 RICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGT 1747
Query: 195 ICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKT 254
C + + CC C VG AW + PG + I C
Sbjct: 1748 TCENELPFNVTKRMCC----CTYNVGKAWNKPCEPCPTPGTADFKTI----------CGN 1793
Query: 255 CSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG 314
G T + + G VD+DEC P C A C N GS+ CE
Sbjct: 1794 IPGFT----------FDIHTGKAVDIDECKEIPGIC-ANGVCINQIGSFRCE-------- 1834
Query: 315 CTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C +G++ C D+DECS + C R N +C N+PGSY C C GF
Sbjct: 1835 -----------CPTGFSYNDLLLVCEDIDECSNGDNLCQR-NADCINSPGSYRCECAAGF 1882
Query: 373 E-ETEDACV 380
+ ACV
Sbjct: 1883 KLSPNGACV 1891
Score = 61.2 bits (147), Expect = 2e-09
Identities = 49/133 (36%), Positives = 56/133 (42%), Gaps = 30/133 (22%)
Query: 266 CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE------------------E 307
C G+ D C DVDECA C Q C N G+Y CE E
Sbjct: 1436 CSEGFTGDGFTCSDVDECAENINLCENGQ-CLNVPGAYRCECEMGFTPASDSRSCQDIDE 1494
Query: 308 CD--SSCV-GCTGEGPG--NCKECISGYA--REHGQCADVDECSLAEKTCVRKNENCYNT 360
C + CV G PG +C C GY R G C D+DEC+ CV N C NT
Sbjct: 1495 CSFQNICVFGTCNNLPGMFHCI-CDDGYELDRTGGNCTDIDECA-DPINCV--NGLCVNT 1550
Query: 361 PGSYVCVCPDGFE 373
PG Y C CP F+
Sbjct: 1551 PGRYECNCPPDFQ 1563
Score = 59.7 bits (143), Expect = 5e-09
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 24/109 (22%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
C G+ L D C+D +EC A P CS C+N GS+ C
Sbjct: 2001 CNEGYELTPDGKNCIDTNECVALPGSCSPGT-CQNLEGSFRCI----------------- 2042
Query: 324 KECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C GY + C D++EC C+ + C NTPG + C+CP GF
Sbjct: 2043 --CPPGYEVKSENCIDINECDEDPNICLFGS--CTNTPGGFQCLCPPGF 2087
Score = 59.7 bits (143), Expect = 5e-09
Identities = 72/286 (25%), Positives = 99/286 (34%), Gaps = 61/286 (21%)
Query: 116 FEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGY--- 172
F FC KV + G C+ SQ P N C + +G C C GY
Sbjct: 2472 FRCFC----KVGYTTDISGTSCIDLDECSQSPKPCNYICK---NTEGSYQCSCPRGYVLQ 2524
Query: 173 -QGPLCTD---CM----DGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWI 224
G C D C + F + C G + + C + C
Sbjct: 2525 EDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGA 2584
Query: 225 RGRNTHTQPGYSSRVWIAAFSPACDESCKT---CSG-----------LTNRDCGECEVGW 270
+G +T +S A +C+ C G L CG C G+
Sbjct: 2585 KGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCG-CPQGY 2643
Query: 271 V--LDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECIS 328
+ CVD +EC+ P C +A C N GSY C C S
Sbjct: 2644 IQHYQWNQCVDENECS-NPNACGSAS-CYNTLGSYKCA-------------------CPS 2682
Query: 329 GYAREH--GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
G++ + C DV+ECS ++ C N C NT G Y+C CP G+
Sbjct: 2683 GFSFDQFSSACHDVNECSSSKNPC---NYGCSNTEGGYLCGCPPGY 2725
Score = 59.3 bits (142), Expect = 6e-09
Identities = 43/151 (28%), Positives = 60/151 (39%), Gaps = 29/151 (19%)
Query: 245 SPACDESCKTCSGLTNRDCGE-CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSY 303
+P + +C G +C E E G +++ C D++ECA P C+ C N GSY
Sbjct: 2221 NPCGNGTCTNVIGSFECNCNEGFEPGPMMN---CEDINECAQNPLLCAFR--CMNTFGSY 2275
Query: 304 TCEECDSSCVGCTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKTCVRKNENCYNTP 361
C C GYA Q C D+DEC+ C + C N
Sbjct: 2276 ECT-------------------CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLI 2316
Query: 362 GSYVCVCPDGFEETED--ACVPPAEAEATEG 390
G+++C+CP G D CV E G
Sbjct: 2317 GTFMCICPPGMARRPDGEGCVDENECRTKPG 2347
Score = 56.2 bits (134), Expect = 5e-08
Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 29/139 (20%)
Query: 242 AAFSPACDE----SCKTCSGLTNRDCGECEVGWVLDEGACV-DVDECAAEPPPCSAAQFC 296
AA+ C+E K L R G G VL D++EC A P C+ + C
Sbjct: 1031 AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGK-C 1089
Query: 297 KNANGSYTCEECDSSCVGCTGEGPGNCKECISGYA--REHGQCADVDECSLAEKTCVRKN 354
+N GS+ C C SG+A E C D+DEC ++ C +
Sbjct: 1090 RNTIGSFKCR-------------------CNSGFALDMEERNCTDIDECRISPDLC--GS 1128
Query: 355 ENCYNTPGSYVCVCPDGFE 373
C NTPGS+ C C +G+E
Sbjct: 1129 GICVNTPGSFECECFEGYE 1147
Score = 55.8 bits (133), Expect = 7e-08
Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 34/141 (24%)
Query: 273 DEGACVDVDECAAEPPPCSAAQFCKNANGSYTC-----------------EECDSSCVG- 314
D+ C+DVDEC E PC CKN GSY C +EC SS G
Sbjct: 1928 DQTMCMDVDEC--ERHPCGNGT-CKNTVGSYNCLCYPGFELTHNNDCLDIDEC-SSFFGQ 1983
Query: 315 ------CTGE-GPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYV 365
C E G C C GY + C D +EC +C C N GS+
Sbjct: 1984 VCRNGRCFNEIGSFKCL-CNEGYELTPDGKNCIDTNECVALPGSC--SPGTCQNLEGSFR 2040
Query: 366 CVCPDGFEETEDACVPPAEAE 386
C+CP G+E + C+ E +
Sbjct: 2041 CICPPGYEVKSENCIDINECD 2061
Score = 53.9 bits (128), Expect = 2e-07
Identities = 82/334 (24%), Positives = 103/334 (30%), Gaps = 104/334 (31%)
Query: 151 NGHCSGDGSRQGDGSCRCHMGYQ-GPLCTDCMDGYFSSL------RNETHSICTVRTGLS 203
NG C R C C +Q P C+D + R + C G+
Sbjct: 1544 NGLCVNTPGRY---ECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVG 1600
Query: 204 DSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIA------AFSP----------- 246
S CC SLG AW G T P +S + F P
Sbjct: 1601 VSRSSCCCSLG------KAW--GNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDID 1652
Query: 247 ACDESCKTCSG------LTNRDCGECEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKN 298
C E C G + C EC G+ L E C D+DEC A P C C N
Sbjct: 1653 ECQELPGLCQGGNCINTFGSFQC-ECPQGYYLSEDTRICEDIDECFAHPGVCGPGT-CYN 1710
Query: 299 ANGSYTC--------------------EECDSSCVG--CTGEGPGN-------------- 322
G+YTC C S G C E P N
Sbjct: 1711 TLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGK 1770
Query: 323 -----CKEC--------------ISGYARE--HGQCADVDECSLAEKTCVRKNENCYNTP 361
C+ C I G+ + G+ D+DEC C N C N
Sbjct: 1771 AWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA--NGVCINQI 1828
Query: 362 GSYVCVCPDGFEETEDACVPPAEAEATEGESPTQ 395
GS+ C CP GF + V E + G++ Q
Sbjct: 1829 GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQ 1862
Score = 52.4 bits (124), Expect = 7e-07
Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPC-SAAQFCKNANGSYTCEECDSSCVGCTGEGPGN 322
C +G+ L D+ C D+DECA C S CKN G++ C
Sbjct: 2279 CPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI---------------- 2322
Query: 323 CKECISGYARE-HGQ-CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEET 375
C G AR G+ C D +EC C +N C N GSY C C +GF+ +
Sbjct: 2323 ---CPPGMARRPDGEGCVDENECRTKPGIC--ENGRCVNIIGSYRCECNEGFQSS 2372
Score = 51.6 bits (122), Expect = 1e-06
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 25/97 (25%)
Query: 279 DVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHG--Q 336
DV+EC P CS Q C N +GS+ CE C GY ++ +
Sbjct: 2171 DVNECLESPGICSNGQ-CINTDGSFRCE-------------------CPMGYNLDYTGVR 2210
Query: 337 CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
C D DECS+ N C N GS+ C C +GFE
Sbjct: 2211 CVDTDECSIGNPC---GNGTCTNVIGSFECNCNEGFE 2244
Score = 46.2 bits (108), Expect = 5e-05
Identities = 66/284 (23%), Positives = 92/284 (32%), Gaps = 61/284 (21%)
Query: 137 CLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMD-------------- 182
C+ + PC GNG C + G +C C+ G++ DC+D
Sbjct: 1932 CMDVDECERHPC-GNGTCK---NTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN 1987
Query: 183 -------GYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGY 235
G F L NE + + D+ L C G PGY
Sbjct: 1988 GRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGY 2047
Query: 236 SSRVWIAAFSPACDESCKTC--SGLTNRDCGE---CEVGWVLDEGA--CVDVDECAA--- 285
+ CDE C TN G C G+VL + C D +
Sbjct: 2048 EVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTN 2107
Query: 286 -EPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGN-CKEC----------ISGYARE 333
E CS + ++ + C GEG G+ C+ C + Y
Sbjct: 2108 FENGKCSVPK-------AFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG 2160
Query: 334 -----HGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
H DV+EC + C N C NT GS+ C CP G+
Sbjct: 2161 TVPSLHDTREDVNECLESPGIC--SNGQCINTDGSFRCECPMGY 2202
Score = 45.4 bits (106), Expect = 9e-05
Identities = 38/132 (28%), Positives = 54/132 (40%), Gaps = 10/132 (7%)
Query: 245 SPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCK-NANGSY 303
+P + +C+ G N C EC G L + +D C+ N NG+
Sbjct: 859 NPCVNGACRNNLGSFN--C-ECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGAT 915
Query: 304 TCEECDSSCVGCTGEGPGNCK---ECISGYAREHG-QCADVDECSLAEKTCVRKNENCYN 359
EC ++ G C+ C G AR G C DV+EC + C N C N
Sbjct: 916 LKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVC--PNGRCVN 973
Query: 360 TPGSYVCVCPDG 371
+ GS+ C CP+G
Sbjct: 974 SKGSFHCECPEG 985
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 79.0 bits (193), Expect = 7e-15
Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 25/131 (19%)
Query: 266 CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKE 325
C G+ AC D DEC+A+P PC A C N GS+ CE + +G G + E
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531
Query: 326 CISGYAREHG-----------------------QCADVDECSLAEKTCVRKNENCYNTPG 362
C + +HG QC D +EC+L+ TC + +C NT G
Sbjct: 2532 CDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC--GSASCRNTLG 2589
Query: 363 SYVCVCPDGFE 373
+ CVCP GF+
Sbjct: 2590 GFRCVCPSGFD 2600
Score = 74.7 bits (182), Expect = 1e-13
Identities = 72/260 (27%), Positives = 90/260 (34%), Gaps = 65/260 (25%)
Query: 153 HCSGDGSRQGDGSCRCHMGYQ----GPLCTD----------CMDGYFSSLRNETHSIC-- 196
HC + +G C C GY G C D C G+ +++ +C
Sbjct: 1169 HCI---NTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 197 ------TVRTGLS----DSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSP 246
+RT + D P CL C G H Q GY R S
Sbjct: 1226 GFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVC-----HCQLGYMVRKGATGCSD 1280
Query: 247 A---------CDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCK 297
CD S +C + C GWV D C D+DEC ++ CS C
Sbjct: 1281 VDECEVGGHNCD-SHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCL 1339
Query: 298 NANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENC 357
N GSY C C G+A + C D DEC AE + N C
Sbjct: 1340 NVPGSYRC-------------------TCRQGFAGDGFFCEDRDEC--AENVDLCDNGQC 1378
Query: 358 YNTPGSYVCVCPDGFEETED 377
N PG Y C C GF+ TED
Sbjct: 1379 LNAPGGYRCECEMGFDPTED 1398
Score = 70.9 bits (172), Expect = 2e-12
Identities = 74/266 (27%), Positives = 93/266 (34%), Gaps = 62/266 (23%)
Query: 151 NGHCSGDGSRQGDGSCRCHMGYQ-GPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPC 209
NG C G C C G+Q P T+C D E + T+ LS S
Sbjct: 2265 NGRCVNTA---GSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV--LQTMCRSLSSS-SEA 2318
Query: 210 CLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDE-SCKTCSGLTNRDC----- 263
C G G W PG S A+ C S T G +C
Sbjct: 2319 VTRAECCCGGGRGWGPRCELCPLPGTS------AYRKLCPHGSGYTAEGRDVDECRMLAH 2372
Query: 264 ----GEC-----------EVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTCE 306
GEC + G+ D A C+D+DEC+ P PC+ CKN GS+ C
Sbjct: 2373 LCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF--LCKNTKGSFLCS 2430
Query: 307 ECDSSCVGCTGEGPGNCKECISGYAREHG--QCADVDECSLAEKTCVRKNENCYNTPGSY 364
C GY E C D+DEC+ + C C NT G++
Sbjct: 2431 -------------------CPRGYLLEEDGRTCKDLDECTSRQHNC---QFLCVNTVGAF 2468
Query: 365 VCVCPDGFEETEDACVPPAEAEATEG 390
C CP GF + AC E A G
Sbjct: 2469 TCRCPPGFTQHHQACFDNDECSAQPG 2494
Score = 70.5 bits (171), Expect = 3e-12
Identities = 72/274 (26%), Positives = 98/274 (35%), Gaps = 49/274 (17%)
Query: 127 CCSPGTYGPDCLACQ-----GGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCM 181
C + Y LAC+ G + PC N C + G C+C GY+ C+
Sbjct: 1748 CPAGFNYNSILLACEDVDECGSRESPCQQNADCI---NIPGSYRCKCTRGYKLSPGGACV 1804
Query: 182 DGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWI 241
RNE I V S+ C + G + + H RG +
Sbjct: 1805 G------RNECREIPNVC-----SHGDCMDTEGSYMCLCH---RGFQASADQTLCMDIDE 1850
Query: 242 AAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANG 301
P + +CK G N C V V G CVD DEC C N G
Sbjct: 1851 CDRQPCGNGTCKNIIGSYNCLCFPGFV--VTHNGDCVDFDECTTLVGQVCRFGHCLNTAG 1908
Query: 302 SYTC------------EEC--DSSCVGCTGEG-PGNCKE--------CISGYAREHGQCA 338
S+ C + C + C+ G PG C+ C G+ + C
Sbjct: 1909 SFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCI 1968
Query: 339 DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
D+DECS C+ C N+PGS+ C+CP GF
Sbjct: 1969 DIDECSEEPNLCLFGT--CTNSPGSFQCLCPPGF 2000
Score = 66.6 bits (161), Expect = 4e-11
Identities = 44/136 (32%), Positives = 59/136 (43%), Gaps = 27/136 (19%)
Query: 279 DVDECAAEPPPCSAAQFCKNANGSYTCE-----ECDSSCVGCTGE---------GPGNCK 324
DV+ECA P C+ C N +GS+ CE D + + C G G C
Sbjct: 2084 DVNECAENPGVCTNG-VCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCT 2142
Query: 325 ECISGY------AREHG---QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEET 375
I G+ E G C D+DECSL C + C+NT GSY+C CP G+
Sbjct: 2143 NVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR---CHNTEGSYLCTCPAGYTLR 2199
Query: 376 EDACVPPAEAEATEGE 391
ED + E +G+
Sbjct: 2200 EDGAMCRDVDECADGQ 2215
Score = 65.9 bits (159), Expect = 6e-11
Identities = 60/191 (31%), Positives = 70/191 (36%), Gaps = 43/191 (22%)
Query: 215 CWRGVGHA---WIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWV 271
C RG+G A ++ GR P Y F C TC C G+
Sbjct: 966 CPRGLGFASRDFLSGR-----PFYKDVNECKVFPGLCTHG--TCRNTVGSFHCACAGGFA 1018
Query: 272 LD--EGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISG 329
LD E C D+DEC P C C N GS+ CE C G
Sbjct: 1019 LDAQERNCTDIDECRISPDLCGQGT-CVNTPGSFECE-------------------CFPG 1058
Query: 330 YAREHG-----QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETE--DACVPP 382
Y E G C DVDEC+ C + C NT GSY C CP G E T AC
Sbjct: 1059 Y--ESGFMLMKNCMDVDECARDPLLC--RGGTCTNTDGSYKCQCPPGHELTAKGTACEDI 1114
Query: 383 AEAEATEGESP 393
E ++G P
Sbjct: 1115 DECSLSDGLCP 1125
Score = 65.9 bits (159), Expect = 6e-11
Identities = 51/157 (32%), Positives = 64/157 (40%), Gaps = 39/157 (24%)
Query: 265 ECEVGWVLDEG-ACVDVDECAAEPPPCSAAQFCKNANGSYTC------------------ 305
+C G+ L G ACV +EC P CS C + GSY C
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSHGD-CMDTEGSYMCLCHRGFQASADQTLCMDI 1848
Query: 306 EECDSSCVGCTGEGPGNCKECISGY---------AREHGQCADVDECS-LAEKTCVRKNE 355
+ECD G G CK I Y +G C D DEC+ L + C +
Sbjct: 1849 DECDRQPCG-----NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC--RFG 1901
Query: 356 NCYNTPGSYVCVCPDGFEETEDA--CVPPAEAEATEG 390
+C NT GS+ C+C DGFE T D CV E + G
Sbjct: 1902 HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAG 1938
Score = 61.6 bits (148), Expect = 1e-09
Identities = 71/258 (27%), Positives = 95/258 (36%), Gaps = 67/258 (25%)
Query: 125 KVCCS--PGT-YGPDCLAC-QGGS---QRPCS-GNGHCSG-DGSRQGDGSCRCHMGYQGP 175
+ CCS PG +G C C Q GS Q C G+G G D SR+ C + G
Sbjct: 2038 RCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGV--- 2094
Query: 176 LCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGY 235
C +G + C L + C + C VGH +G T+
Sbjct: 2095 ----CTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDEC--SVGHPCGQGTCTNV---- 2144
Query: 236 SSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQF 295
I F AC + + +T C D+DEC+ P C+
Sbjct: 2145 -----IGGFECACADGFEPGLMMT-----------------CEDIDECSLNPLLCAFR-- 2180
Query: 296 CKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYA-REHG-QCADVDECSLAEKTCVRK 353
C N GSY C C +GY RE G C DVDEC+ ++ C +
Sbjct: 2181 CHNTEGSYLCT-------------------CPAGYTLREDGAMCRDVDECADGQQDCHAR 2221
Query: 354 NENCYNTPGSYVCVCPDG 371
C N G++ CVCP G
Sbjct: 2222 GMECKNLIGTFACVCPPG 2239
Score = 60.5 bits (145), Expect = 3e-09
Identities = 39/101 (38%), Positives = 47/101 (46%), Gaps = 24/101 (23%)
Query: 279 DVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGY-AREHGQ- 336
D++ECA +P C A C+N GSY C C GY A G+
Sbjct: 682 DINECALDPEVC-ANGVCENLRGSYRCV-------------------CNLGYEAGASGKD 721
Query: 337 CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETED 377
C DVDEC+L C N C N+PGSY C CP GF +D
Sbjct: 722 CTDVDECALNSLLC--DNGWCQNSPGSYSCSCPPGFHFWQD 760
Score = 60.1 bits (144), Expect = 3e-09
Identities = 70/278 (25%), Positives = 92/278 (33%), Gaps = 62/278 (22%)
Query: 132 TYGPDCLACQGG-----SQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFS 186
T G AC GG +R C+ C G G+C + G +C GY S
Sbjct: 1005 TVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTC---VNTPGSFECECFPGYES 1061
Query: 187 SLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSP 246
+ + P C C G PG+ + A
Sbjct: 1062 GFMLMKNCMDVDECARD---PLLCRGGTCTNTDG-----SYKCQCPPGHE----LTAKGT 1109
Query: 247 ACDE--SCKTCSGLTNR----------DCGECEVGW--VLDEGACVDVDECAAEPPPCSA 292
AC++ C GL C C G+ D CVD++EC + C
Sbjct: 1110 ACEDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCDV 1168
Query: 293 AQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYA--REHGQCADVDECSLAEKTC 350
C N GSY C C GY+ + CADVDEC + C
Sbjct: 1169 --HCINTEGSYRC-------------------SCGQGYSLMPDGRACADVDECEENPRVC 1207
Query: 351 VRKNENCYNTPGSYVCVCPDGFEETED--ACVPPAEAE 386
+C N PG + C+C DGF T D CV E +
Sbjct: 1208 --DQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECD 1243
Score = 59.7 bits (143), Expect = 5e-09
Identities = 40/116 (34%), Positives = 50/116 (43%), Gaps = 27/116 (23%)
Query: 265 ECEVGWVLD-EGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
EC VG+ D G C+DVDEC + P C C N G+Y C
Sbjct: 434 ECNVGYTQDVRGECIDVDECTSSP--CHHGD-CVNIPGTYHCR----------------- 473
Query: 324 KECISGYAREHGQ--CADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETED 377
C G+ + C DVDEC ++ C C NT GS+ CVC GFE + D
Sbjct: 474 --CYPGFQATPTRQACVDVDECIVSGGLC--HLGRCVNTEGSFQCVCNAGFELSPD 525
Score = 53.5 bits (127), Expect = 3e-07
Identities = 60/228 (26%), Positives = 78/228 (34%), Gaps = 60/228 (26%)
Query: 151 NGHCSGDGSRQGDGSCRCHMGYQ-GPLCTDCMDGYFSSLRNETHS------ICTVRTGLS 203
NG C + G C C ++ P C+D + ETH C+ G+
Sbjct: 1457 NGVCI---NTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVG 1513
Query: 204 DSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDC 263
+ CC SL G AW G + A + C G
Sbjct: 1514 VTRASCCCSL------GRAW----------GNPCELCPMANTTEYRTLCPGGEGFQPN-- 1555
Query: 264 GECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
+ +L+ D+DEC P C C N GS+ C
Sbjct: 1556 ---RITVILE-----DIDECQELPGLCQGGD-CVNTFGSFQC------------------ 1588
Query: 324 KECISGY-AREHGQ-CADVDECSLAEKTCVRKNENCYNTPGSYVCVCP 369
EC GY EH + C D+DECS C CYNT G+Y CVCP
Sbjct: 1589 -ECPPGYHLSEHTRICEDIDECSTHSGIC--GPGTCYNTLGNYTCVCP 1633
Score = 53.1 bits (126), Expect = 4e-07
Identities = 47/171 (27%), Positives = 57/171 (33%), Gaps = 53/171 (30%)
Query: 248 CDES-CKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE 306
CD C+ G + C W D C DVDEC + P + C+N GSYTC+
Sbjct: 735 CDNGWCQNSPGSYSCSCPPGFHFWQ-DTEICKDVDECLSSP---CVSGVCRNLAGSYTCK 790
Query: 307 -----ECDSSCVGCTGEGPGNC-------------------------------------- 323
D S C G C
Sbjct: 791 CGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCE 850
Query: 324 --KECISGYAREHG-QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG 371
C G+AR G C DV+EC C N C NT GS+ C CP+G
Sbjct: 851 IDPACARGFARMTGVTCDDVNECESFPGVC--PNGRCVNTAGSFRCECPEG 899
Score = 50.8 bits (120), Expect = 2e-06
Identities = 72/301 (23%), Positives = 92/301 (30%), Gaps = 84/301 (27%)
Query: 117 EWFCVKTLKVCCSPGTYGPDCLACQG-GSQRPCSGNGHCSG------------------- 156
E FC + C+ GT P C +G G C G C G
Sbjct: 92 EGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPIC 151
Query: 157 ------DGSRQGDGSCRCHMGYQGPLC-TDCMDG-YFSSLRNE--THSICTVRTGLSDSY 206
G G C C G+ GP C D G F + E H + TGL +
Sbjct: 152 DRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQL----TGLVCTK 207
Query: 207 PPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGEC 266
CC + VG AW C+ C + C
Sbjct: 208 ALCCAT------VGRAW-------------------------GLPCELCPAQPH----PC 232
Query: 267 EVGWV--LDEGACVDVDECAAEPPPCSAAQFCKNANGSYTC-----EECDSSCVGCTGEG 319
G++ + GAC DVDEC A P C C N GS+ C S C
Sbjct: 233 RRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 320 PGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPD-GFEETEDA 378
G C + G G+CA + C C+ G +CP G E +
Sbjct: 292 AGACFSVLFG-----GRCAGDLAGHYTRRQCCCDRGRCW-AAGPVPELCPPRGSNEFQQL 345
Query: 379 C 379
C
Sbjct: 346 C 346
Score = 46.6 bits (109), Expect = 4e-05
Identities = 76/319 (23%), Positives = 103/319 (32%), Gaps = 98/319 (30%)
Query: 128 CSPGTYGPDCLACQG-----GSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMD 182
C PG G D C + CS G C + G C C G+ G D
Sbjct: 1308 CLPGWVG-DGFECHDLDECVSQEHRCSPRGDCL---NVPGSYRCTCRQGFAG-------D 1356
Query: 183 GYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWR---GVGHAWIRGRNTHTQPGYSSRV 239
G+F R+E C L D+ C + G +R +G ++
Sbjct: 1357 GFFCEDRDE----CAENVDLCDN-GQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG 1411
Query: 240 WIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCK 297
+ AF SC+ G+ C G+ LD G C D++ECA +P C C
Sbjct: 1412 NLCAFG-----SCENLPGMFRCICNG---GYELDRGGGNCTDINECA-DPVNCING-VCI 1461
Query: 298 NANGSYTCE-----ECDSSCVGCT------------------------------------ 316
N GSY C E + S VGC
Sbjct: 1462 NTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCC 1521
Query: 317 --GEGPGN-CKECISGYAREHGQCA----------------DVDECSLAEKTCVRKNENC 357
G GN C+ C E+ D+DEC C + +C
Sbjct: 1522 SLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC--QGGDC 1579
Query: 358 YNTPGSYVCVCPDGFEETE 376
NT GS+ C CP G+ +E
Sbjct: 1580 VNTFGSFQCECPPGYHLSE 1598
Score = 45.4 bits (106), Expect = 9e-05
Identities = 38/110 (34%), Positives = 49/110 (44%), Gaps = 28/110 (25%)
Query: 266 CEVGWVLDEGA----CVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPG 321
C +G+ + GA C DVDECA C +C+N+ GSY+C SC PG
Sbjct: 709 CNLGY--EAGASGKDCTDVDECALNSLLCDNG-WCQNSPGSYSC-----SC------PPG 754
Query: 322 NCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG 371
+ ++ C DVDEC CV + C N GSY C C G
Sbjct: 755 ------FHFWQDTEICKDVDEC--LSSPCV--SGVCRNLAGSYTCKCGPG 794
Score = 45.4 bits (106), Expect = 9e-05
Identities = 59/224 (26%), Positives = 79/224 (35%), Gaps = 43/224 (19%)
Query: 117 EWFCVKTLKVC---CSPG-------TYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSC 166
++ CV T+ C PG + D + Q G PC +GHC + G C
Sbjct: 2458 QFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPG---PCGAHGHCH---NTPGSFRC 2511
Query: 167 RCHMGYQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRG 226
CH G+ T G+ NE + G C LG +R + +G
Sbjct: 2512 ECHQGF-----TLVSSGHGCEDVNECDGPHRCQHG-------CQNQLGGYRC---SCPQG 2556
Query: 227 RNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDE--GACVDVDECA 284
H+Q A SP S + L C C G+ D+ G C +VDECA
Sbjct: 2557 FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRC-VCPSGFDFDQALGGCQEVDECA 2615
Query: 285 AEPPPCSAAQFCKNANGSYTC-------EECDSSCVGCTGEGPG 321
PCS + C N G + C CV G PG
Sbjct: 2616 GRRGPCSYS--CANTPGGFLCGCPQGYFRAGQGHCVSGLGFSPG 2657
Score = 42.7 bits (99), Expect = 6e-04
Identities = 40/168 (23%), Positives = 56/168 (33%), Gaps = 70/168 (41%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
C+ G++L G C+D+DEC + P C N GS+ C+ VG G
Sbjct: 557 CKPGFLLAPGGHYCMDIDEC--QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG------ 608
Query: 324 KECISGYAR-------EHGQCA-------------------------------------- 338
+ C+ + R E G CA
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQA 668
Query: 339 -------------DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
D++EC+L + C N C N GSY CVC G+E
Sbjct: 669 LCSSGLGITTDGRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYE 714
Score = 37.4 bits (85), Expect = 0.024
Identities = 68/290 (23%), Positives = 92/290 (31%), Gaps = 87/290 (30%)
Query: 152 GHCSGDGSRQ---GDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPP 208
GH G G+ G C C G++ L C D SL +C R ++
Sbjct: 2133 GHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNP---LLCAFRCHNTEGSYL 2189
Query: 209 CCLSLGCWRGVGHAWIR-------GRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNR 261
C G A R G+ G + I F+ C + G
Sbjct: 2190 CTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPG---- 2245
Query: 262 DCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE------------EC- 308
GE C D +EC A+P C + C N GS+ C+ EC
Sbjct: 2246 -SGE----------GCTDDNECHAQPDLCVNGR-CVNTAGSFRCDCDEGFQPSPTLTECH 2293
Query: 309 -----------------------------DSSCVGCTGEGPGNCKEC----ISGYAR--E 333
+ C G G GP C+ C S Y +
Sbjct: 2294 DIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP-RCELCPLPGTSAYRKLCP 2352
Query: 334 HG-----QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA 378
HG + DVDEC + C + C N+ GS+ C C G+ T DA
Sbjct: 2353 HGSGYTAEGRDVDECRMLAHLCA--HGECINSLGSFRCHCQAGY--TPDA 2398
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 79.0 bits (193), Expect = 7e-15
Identities = 75/290 (25%), Positives = 104/290 (35%), Gaps = 72/290 (24%)
Query: 136 DCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGY--------------QGPLCTDCM 181
+C GG Q+ C + G C+CH G+ +G C +
Sbjct: 120 ECQDNNGGCQQICV---------NAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKD 170
Query: 182 DGYFSSLRNETHS--ICTVRTG--LSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQP--GY 235
G R C R G L+ + C L+ C G G +T T P G
Sbjct: 171 HGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHSCEDTDTGPTCGC 228
Query: 236 SSRVWIAAFSPACDESCKTCSGLTNRDCGE--------CEVGWVL--DEGACVDVDECAA 285
+ + + C E+C +G +R C + C VG+ L D C D++EC
Sbjct: 229 HQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLV 288
Query: 286 EPPPCSAAQFCKNANGSYTC------------------------EECDSSCVGCTGEGPG 321
C FC+N GS+ C CD C+ G
Sbjct: 289 NNGGCD--HFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQC 346
Query: 322 NCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG 371
C Y H C DVDECS++ +C ++ C NT GSY CVCP G
Sbjct: 347 LCHRGYILYGTTH--CGDVDECSMSNGSC---DQGCVNTKGSYECVCPPG 391
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/117 (32%), Positives = 45/117 (38%), Gaps = 26/117 (22%)
Query: 278 VDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQC 337
VDVDEC+ C C+N SY C C GY E QC
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKC-------------------LCKPGYKGEGKQC 72
Query: 338 ADVDEC--SLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA--CVPPAEAEATEG 390
D+DEC CV + C N PG+Y C C DGF D C+ E + G
Sbjct: 73 EDIDECENDYYNGGCVHE---CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNG 126
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 26/119 (21%)
Query: 266 CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKE 325
C+ G+ + C D+DEC + C N G+Y C
Sbjct: 61 CKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRC-------------------T 101
Query: 326 CISGYAREHG--QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF--EETEDACV 380
C G+ H C DVDEC C + C N GSY C C GF + + C+
Sbjct: 102 CFDGFMLAHDGHNCLDVDECQDNNGGC---QQICVNAMGSYECQCHSGFFLSDNQHTCI 157
Score = 36.2 bits (82), Expect = 0.054
Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 27/131 (20%)
Query: 248 CDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEE 307
C SC+ T CG C + L ++ CA C CK+ C
Sbjct: 213 CQHSCEDTD--TGPTCG-CHQKYALHSDGRTCIETCAVNNGGCDRT--CKDTATGVRC-- 265
Query: 308 CDSSC-VGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVC 366
SC VG T + G C D++EC + C + C NT GS+ C
Sbjct: 266 ---SCPVGFTLQPDGKT-------------CKDINECLVNNGGC---DHFCRNTVGSFEC 306
Query: 367 VCPDGFEETED 377
C G++ D
Sbjct: 307 GCRKGYKLLTD 317
>gi|190343004 EGF-containing fibulin-like extracellular matrix
protein 2 [Homo sapiens]
Length = 443
Score = 78.6 bits (192), Expect = 9e-15
Identities = 46/127 (36%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 265 ECEVG--WVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG-CTGEGPG 321
EC G W D C DV+EC P C C N G Y C ++ + GEGP
Sbjct: 38 ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPP 97
Query: 322 -------NCKECISGYARE-HGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
+ C GY + C DVDEC+ A C R +++C+N PGSY C CPDG+
Sbjct: 98 PPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDC-RPSQDCHNLPGSYQCTCPDGYR 156
Query: 374 ETEDACV 380
+ CV
Sbjct: 157 KIGPECV 163
Score = 63.5 bits (153), Expect = 3e-10
Identities = 35/101 (34%), Positives = 45/101 (44%), Gaps = 24/101 (23%)
Query: 273 DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAR 332
D+ +CVDVDECA C +Q C N GSY C C GY +
Sbjct: 117 DQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCT-------------------CPDGYRK 157
Query: 333 EHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
+C D+DEC + C + C N PGS+ C C GF+
Sbjct: 158 IGPECVDIDECRY--RYCQHR---CVNLPGSFRCQCEPGFQ 193
Score = 39.7 bits (91), Expect = 0.005
Identities = 51/188 (27%), Positives = 66/188 (35%), Gaps = 36/188 (19%)
Query: 127 CCSPGTY---GPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQ-GPLCTDCMD 182
C P Y GP+C+ R C C + G C+C G+Q GP C+D
Sbjct: 149 CTCPDGYRKIGPECVDIDECRYRYCQHR--CV---NLPGSFRCQCEPGFQLGPNNRSCVD 203
Query: 183 GYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIR---GRNTHTQPGYSSRV 239
NE D PC C+ G R G H S +
Sbjct: 204 V------NEC-----------DMGAPC--EQRCFNSYGTFLCRCHQGYELHRDGFSCSDI 244
Query: 240 WIAAFSP-ACDESCKTCSGLTNRDCGECEVGW-VLDEGACVDVDECAAEPPPCSAAQFCK 297
++S C C G R C G+ +L C D+DEC + CS AQ C
Sbjct: 245 DECSYSSYLCQYRCVNEPG---RFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCV 301
Query: 298 NANGSYTC 305
N +G Y C
Sbjct: 302 NFHGGYRC 309
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 78.6 bits (192), Expect = 9e-15
Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 36/173 (20%)
Query: 248 CDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE- 306
CD + G + EC +G+ D C D+DEC+ +P C + C N G++ CE
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCEC 738
Query: 307 ------ECDSSCVGCTGEGPGNCKE-------------------------CISGYAREHG 335
+ +CV + P N E C+ G++ +
Sbjct: 739 VEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQ 798
Query: 336 QCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEAT 388
C DVDEC + + + CYNTPGS+ C C G++ CV P E E T
Sbjct: 799 ACQDVDEC---QPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV-PGEVEKT 847
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 78.2 bits (191), Expect = 1e-14
Identities = 54/178 (30%), Positives = 66/178 (37%), Gaps = 34/178 (19%)
Query: 245 SPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYT 304
S CD + + G EC G+ D CVD +ECA C C N GSY
Sbjct: 767 SHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYR 826
Query: 305 CE----------------------ECDSSCVGCTGEGPGNCKE---------CISGYARE 333
CE C+ C G C C+ GYA +
Sbjct: 827 CECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGD 886
Query: 334 HGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGE 391
QC DVDECS E C CYNTPGS+ C C G+ C+P + + T E
Sbjct: 887 GHQCTDVDECS--ENRC-HPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCE 941
Score = 52.8 bits (125), Expect = 6e-07
Identities = 65/273 (23%), Positives = 92/273 (33%), Gaps = 54/273 (19%)
Query: 157 DGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPC-----CL 211
DGS D + RCH G +C GY RN C + + C C+
Sbjct: 765 DGSHMCDTTARCHPGTGVDYTCECASGYQGDGRN-----CVDENECATGFHRCGPNSVCI 819
Query: 212 SL----GCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGE-- 265
+L C G+ + R+T + I + C++ TC+ C
Sbjct: 820 NLPGSYRCECRSGYEFADDRHT--------CILITPPANPCEDGSHTCAPAGQARCVHHG 871
Query: 266 -------CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG---- 314
C G+ D C DVDEC+ C A C N GS++C C G
Sbjct: 872 GSTFSCACLPGYAGDGHQCTDVDECSEN--RCHPAATCYNTPGSFSC-RCQPGYYGDGFQ 928
Query: 315 CTGEGPGNCKECISGYAREHGQCA------DVDECSLAEKTCVRKNENCYNTPGSYVCVC 368
C + + C Q A + +C + C+ + G CV
Sbjct: 929 CIPDSTSSLTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQ---CHGSTGFCWCVD 985
Query: 369 PDGFE----ETEDACVPPAEAEATEGESPTQLP 397
PDG E +T PP + E PTQ P
Sbjct: 986 PDGHEVPGTQTPPGSTPPHCGPSPE---PTQRP 1015
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 77.4 bits (189), Expect = 2e-14
Identities = 84/294 (28%), Positives = 112/294 (38%), Gaps = 89/294 (30%)
Query: 128 CSPG-------TYGPDCLACQGGSQRPCS-GNGHCSGDGSRQGDGSCRCHMGYQ------ 173
C+PG Y D C+ PC G G C G G +C C+ GY+
Sbjct: 601 CNPGYRSHPQHRYCVDVNECEA---EPCGPGRGICMNTG---GSYNCHCNRGYRLHVGAG 654
Query: 174 GPLCTD---------CMDGYFSSLRNETHSICTVRTG--LSDSYPPCCLSLGCWRGVGHA 222
G C D C DG F + H C G L S PP C + R
Sbjct: 655 GRSCVDLNECAKPHLCGDGGFC-INFPGHYKCNCYPGYRLKASRPPVCEDIDECRDP--- 710
Query: 223 WIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEG-ACVDVD 281
S D C+ G + C C+ G+ G AC DV+
Sbjct: 711 ----------------------SSCPDGKCENKPG--SFKCIACQPGYRSQGGGACRDVN 746
Query: 282 ECAAEPPPCSAAQFCKNANGSYTC------------------EECDSSCV---GCTGEGP 320
ECA E PCS +C+N GS+ C +EC++ V G P
Sbjct: 747 ECA-EGSPCSPG-WCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTP 804
Query: 321 GNCK-ECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG 371
G+ + +C+SGY +R+ C D+DEC C+ +C NT GSY C+CP G
Sbjct: 805 GSFQCQCLSGYHLSRDRSHCEDIDECDFPA-ACI--GGDCINTNGSYRCLCPQG 855
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 306 EECDSSCVGCTGEGPGNCKECISGYARE--HGQCADVDEC-SLAEKTCVRKNENCYNTPG 362
+EC C G EC G+ + +C D+DEC L ++ + K+E C NT G
Sbjct: 1219 DECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSG 1278
Query: 363 SYVCVCPDGFEET--EDACVP 381
S+ CVC GF + ACVP
Sbjct: 1279 SFRCVCKAGFARSRPHGACVP 1299
Score = 45.1 bits (105), Expect = 1e-04
Identities = 74/284 (26%), Positives = 106/284 (37%), Gaps = 61/284 (21%)
Query: 130 PGTYGPDCLACQ-------GGSQRP---CSGNGHCSGDGSRQGDGS--CRCHMGY----Q 173
PG++ C+ACQ GG+ R C+ CS GS C C GY
Sbjct: 722 PGSF--KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 174 GPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQP 233
G C D + + + + IC+ G S+ CLS G+ R R+
Sbjct: 780 GRSCLDVDECEAGDVCD--NGICSNTPG---SFQCQCLS-------GYHLSRDRS----- 822
Query: 234 GYSSRVWIAAFSPAC-DESCKTCSGLTNRDCGECEVGWVLDEGA-CVDVDECAAEPPPCS 291
+ + F AC C +G C + G L G C D+DEC+ +P C
Sbjct: 823 -HCEDIDECDFPAACIGGDCINTNGSYRCLCPQ---GHRLVGGRKCQDIDECSQDPSLCL 878
Query: 292 AAQFCKNANGSYTCEECDSSCV------GCTG-EGPGNCKECISGYAREHGQCADVDECS 344
CKN GSY C CD GC E P + KEC + + C V +
Sbjct: 879 PHGACKNLQGSYVC-VCDEGFTPTQDQHGCEEVEQPHHKKECYLNF-DDTVFCDSVLATN 936
Query: 345 LAEKTCVRK-----NENCYNTP------GSYVCVCPDGFEETED 377
+ ++ C ++C P + +CPDG T+D
Sbjct: 937 VTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQD 980
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 28/141 (19%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
C+ G+ D CVDVDEC E + C+N G Y C +C P
Sbjct: 1021 CKQGFYYDGNLLECVDVDECLDESNCRNGV--CENTRGGYRC-----ACTPPAEYSPAQ- 1072
Query: 324 KECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVP-P 382
++C+S + +C D C + C N PGSY C C VP P
Sbjct: 1073 RQCLSPEEMDVDECQDPAAC---------RPGRCVNLPGSYRCEC-------RPPWVPGP 1116
Query: 383 AEAEATEGESPTQ-LPSREDL 402
+ + ESP + P R D+
Sbjct: 1117 SGRDCQLPESPAERAPERRDV 1137
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 301 GSYTCEECDS-SCVGCTGEGPGNCK---ECISGYAREHG-QCADVDECSLAEKTCVRKNE 355
G C +C G GP + +C GY R + C D++EC++ V ++
Sbjct: 312 GQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPG---VCRHG 368
Query: 356 NCYNTPGSYVCVCPDG 371
+C N PGSY CVCP G
Sbjct: 369 DCLNNPGSYRCVCPPG 384
Score = 32.3 bits (72), Expect = 0.78
Identities = 62/257 (24%), Positives = 82/257 (31%), Gaps = 67/257 (26%)
Query: 127 CCSPGTYGP---DCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMG---YQGPLCTDC 180
C P Y P CL+ + C C GS RC GP DC
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDC 1121
Query: 181 MDGYFSSLRN-ETHSICTVRTGLSD-----------SYPPCCLSLGCWRGVGHAWI---- 224
+ R E +C + G ++ CC G RG G
Sbjct: 1122 QLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG--RGWGAQCRPCPP 1179
Query: 225 RGRNTH--TQPGYSSRVW----IAAFSPACDES--------CKTCSGLTNRDCG----EC 266
RG +H T S+ W + P DE C+ SG G EC
Sbjct: 1180 RGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCEC 1239
Query: 267 EVGWVLD--EGACVDVDECAA--EPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGN 322
G+ LD CVD+DEC + ++ C N +GS+ C
Sbjct: 1240 PGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC----------------- 1282
Query: 323 CKECISGYARE--HGQC 337
C +G+AR HG C
Sbjct: 1283 --VCKAGFARSRPHGAC 1297
Score = 29.6 bits (65), Expect = 5.0
Identities = 14/35 (40%), Positives = 16/35 (45%), Gaps = 7/35 (20%)
Query: 339 DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
D DEC CV + PG VC CP GF+
Sbjct: 1217 DSDECRCVSGRCVPR-------PGGAVCECPGGFQ 1244
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 77.4 bits (189), Expect = 2e-14
Identities = 84/294 (28%), Positives = 112/294 (38%), Gaps = 89/294 (30%)
Query: 128 CSPG-------TYGPDCLACQGGSQRPCS-GNGHCSGDGSRQGDGSCRCHMGYQ------ 173
C+PG Y D C+ PC G G C G G +C C+ GY+
Sbjct: 601 CNPGYRSHPQHRYCVDVNECEA---EPCGPGRGICMNTG---GSYNCHCNRGYRLHVGAG 654
Query: 174 GPLCTD---------CMDGYFSSLRNETHSICTVRTG--LSDSYPPCCLSLGCWRGVGHA 222
G C D C DG F + H C G L S PP C + R
Sbjct: 655 GRSCVDLNECAKPHLCGDGGFC-INFPGHYKCNCYPGYRLKASRPPVCEDIDECRDP--- 710
Query: 223 WIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEG-ACVDVD 281
S D C+ G + C C+ G+ G AC DV+
Sbjct: 711 ----------------------SSCPDGKCENKPG--SFKCIACQPGYRSQGGGACRDVN 746
Query: 282 ECAAEPPPCSAAQFCKNANGSYTC------------------EECDSSCV---GCTGEGP 320
ECA E PCS +C+N GS+ C +EC++ V G P
Sbjct: 747 ECA-EGSPCSPG-WCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTP 804
Query: 321 GNCK-ECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG 371
G+ + +C+SGY +R+ C D+DEC C+ +C NT GSY C+CP G
Sbjct: 805 GSFQCQCLSGYHLSRDRSHCEDIDECDFPA-ACI--GGDCINTNGSYRCLCPQG 855
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 306 EECDSSCVGCTGEGPGNCKECISGYARE--HGQCADVDEC-SLAEKTCVRKNENCYNTPG 362
+EC C G EC G+ + +C D+DEC L ++ + K+E C NT G
Sbjct: 1172 DECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSG 1231
Query: 363 SYVCVCPDGFEET--EDACVP 381
S+ CVC GF + ACVP
Sbjct: 1232 SFRCVCKAGFARSRPHGACVP 1252
Score = 45.1 bits (105), Expect = 1e-04
Identities = 74/284 (26%), Positives = 106/284 (37%), Gaps = 61/284 (21%)
Query: 130 PGTYGPDCLACQ-------GGSQRP---CSGNGHCSGDGSRQGDGS--CRCHMGY----Q 173
PG++ C+ACQ GG+ R C+ CS GS C C GY
Sbjct: 722 PGSF--KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPD 779
Query: 174 GPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQP 233
G C D + + + + IC+ G S+ CLS G+ R R+
Sbjct: 780 GRSCLDVDECEAGDVCD--NGICSNTPG---SFQCQCLS-------GYHLSRDRS----- 822
Query: 234 GYSSRVWIAAFSPAC-DESCKTCSGLTNRDCGECEVGWVLDEGA-CVDVDECAAEPPPCS 291
+ + F AC C +G C + G L G C D+DEC+ +P C
Sbjct: 823 -HCEDIDECDFPAACIGGDCINTNGSYRCLCPQ---GHRLVGGRKCQDIDECSQDPSLCL 878
Query: 292 AAQFCKNANGSYTCEECDSSCV------GCTG-EGPGNCKECISGYAREHGQCADVDECS 344
CKN GSY C CD GC E P + KEC + + C V +
Sbjct: 879 PHGACKNLQGSYVC-VCDEGFTPTQDQHGCEEVEQPHHKKECYLNF-DDTVFCDSVLATN 936
Query: 345 LAEKTCVRK-----NENCYNTP------GSYVCVCPDGFEETED 377
+ ++ C ++C P + +CPDG T+D
Sbjct: 937 VTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQD 980
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 301 GSYTCEECDS-SCVGCTGEGPGNCK---ECISGYAREHG-QCADVDECSLAEKTCVRKNE 355
G C +C G GP + +C GY R + C D++EC++ V ++
Sbjct: 312 GQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPG---VCRHG 368
Query: 356 NCYNTPGSYVCVCPDG 371
+C N PGSY CVCP G
Sbjct: 369 DCLNNPGSYRCVCPPG 384
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/104 (32%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 301 GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHG--QCADVDECSLAEKTCVRKNENCY 358
GS C+E C PG C G+ + +C DVDEC L E C +N C
Sbjct: 1001 GSEICKEGK-----CVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNC--RNGVCE 1052
Query: 359 NTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSREDL 402
NT G Y C C T A PA+ + E + P R D+
Sbjct: 1053 NTRGGYRCAC------TPPAEYSPAQRQCLSPEEMERAPERRDV 1090
Score = 30.4 bits (67), Expect = 3.0
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 25/79 (31%)
Query: 265 ECEVGWVLD--EGACVDVDECAA--EPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGP 320
EC G+ LD CVD+DEC + ++ C N +GS+ C
Sbjct: 1191 ECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRC--------------- 1235
Query: 321 GNCKECISGYARE--HGQC 337
C +G+AR HG C
Sbjct: 1236 ----VCKAGFARSRPHGAC 1250
Score = 29.6 bits (65), Expect = 5.0
Identities = 14/35 (40%), Positives = 16/35 (45%), Gaps = 7/35 (20%)
Query: 339 DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFE 373
D DEC CV + PG VC CP GF+
Sbjct: 1170 DSDECRCVSGRCVPR-------PGGAVCECPGGFQ 1197
Score = 29.3 bits (64), Expect = 6.6
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 4/42 (9%)
Query: 266 CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTC 305
C+ G+ D CVDVDEC E + C+N G Y C
Sbjct: 1021 CKQGFYYDGNLLECVDVDECLDESNCRNGV--CENTRGGYRC 1060
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 77.4 bits (189), Expect = 2e-14
Identities = 43/113 (38%), Positives = 49/113 (43%), Gaps = 25/113 (22%)
Query: 266 CEVGWVLDEG-ACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCK 324
C G+ +DE CVDVDECA + C+ Q C N G YTC
Sbjct: 113 CRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC------------------- 153
Query: 325 ECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETED 377
C GY GQC D+DEC C + C N PGSY C C GF ED
Sbjct: 154 SCTDGYWLLEGQCLDIDECRYG--YC---QQLCANVPGSYSCTCNPGFTLNED 201
Score = 64.7 bits (156), Expect = 1e-10
Identities = 43/143 (30%), Positives = 53/143 (37%), Gaps = 28/143 (19%)
Query: 265 ECEVGWVLDE--GACVDVDECAAEPPPCSAAQFCKNANGSYTC----------EECDSSC 312
+C G+ LD G C+D+DEC P C C N NG Y C +
Sbjct: 26 QCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYS 85
Query: 313 VGCTGEGPGNCKE--------------CISGYAR-EHGQCADVDECSLAEKTCVRKNENC 357
+G P C GY E QC DVDEC+ C + C
Sbjct: 86 TPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQC-NPTQIC 144
Query: 358 YNTPGSYVCVCPDGFEETEDACV 380
NT G Y C C DG+ E C+
Sbjct: 145 INTEGGYTCSCTDGYWLLEGQCL 167
Score = 42.4 bits (98), Expect = 8e-04
Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 320 PGNCK-ECISGYA--REHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCV 367
PGN + +C +G+ R+ GQC D+DEC + C R + C N G Y+C+
Sbjct: 20 PGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEAC-RGDMMCVNQNGGYLCI 69
Score = 36.6 bits (83), Expect = 0.041
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 15/73 (20%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEE-----------CDSSC 312
C G++L D +C D++EC C+ Q C N G + C + D+ C
Sbjct: 273 CPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNRC 332
Query: 313 VGCTGEGPGNCKE 325
+ C E PG C++
Sbjct: 333 M-CPAENPG-CRD 343
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 77.0 bits (188), Expect = 3e-14
Identities = 72/260 (27%), Positives = 95/260 (36%), Gaps = 48/260 (18%)
Query: 148 CSGNGHCSGDGSRQGDGS-CRCHMGYQ----GPLCTD---CMDGYFSSLRNETHSICTVR 199
C G G C GD C C +GYQ G C D C+ G S E+ C
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES---CINT 236
Query: 200 TGLSDSYPPCCLSLGCWR----GVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTC 255
G S C R G G+ + S + C T
Sbjct: 237 VG----------SFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQN---TL 283
Query: 256 SGLTNRDCGECEVGWVLDE-GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG 314
R +C+ G++ D G C+D++EC + PC C N GSYTC++
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK------- 336
Query: 315 CTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG- 371
N C GY E +C DVDEC+ + C K C N+PGS+ C C G
Sbjct: 337 -------NVPNCGRGYHLNEEGTRCVDVDECAPPAEPC-GKGHRCVNSPGSFRCECKTGY 388
Query: 372 -FEETEDACVPPAEAEATEG 390
F+ CV E + G
Sbjct: 389 YFDGISRMCVDVNECQRYPG 408
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 42/145 (28%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSY----------------TCEE 307
C VG+ L D +C D++EC++ PCS Q C N GSY TCE+
Sbjct: 426 CSVGFRLSVDGRSCEDINECSSS--PCS--QECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 308 ------------CDSSCVGCTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRK 353
C C+ G +C SGY A C D+DEC C
Sbjct: 482 IDECALPTGGHICSYRCINIPGSFQCSCPS--SGYRLAPNGRNCQDIDECVTGIHNC-SI 538
Query: 354 NENCYNTPGSYVCV---CPDGFEET 375
NE C+N G + C+ CP+ + +
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRS 563
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/287 (23%), Positives = 94/287 (32%), Gaps = 57/287 (19%)
Query: 134 GPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCR----CHMGYQGPLCTDCMDGYFSSLR 189
G C+ G + C + C D SC+ C G L S R
Sbjct: 230 GESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 190 NETHSICTVRTG-LSDSYPPC-----CLSLGCWRGVGHAWIR--------------GRNT 229
C ++G + D+ C CLS+ +GH I GR
Sbjct: 288 CRPKLQC--KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 230 HTQPGYSSRVWIAAFSPACDESCK--TCSGLTNRDCGECEVGWVLD--EGACVDVDECAA 285
H + V + +P + K C EC+ G+ D CVDV+EC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 286 EPPPCSAAQFCKNANGSYTC------------------EECDSS-----CVGCTGEGPGN 322
P + C+N GSY C EC SS C G
Sbjct: 406 YPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCY 464
Query: 323 CKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCP 369
C+ + C D+DEC+L + + C N PGS+ C CP
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHI-CSYRCINIPGSFQCSCP 510
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 77.0 bits (188), Expect = 3e-14
Identities = 72/260 (27%), Positives = 95/260 (36%), Gaps = 48/260 (18%)
Query: 148 CSGNGHCSGDGSRQGDGS-CRCHMGYQ----GPLCTD---CMDGYFSSLRNETHSICTVR 199
C G G C GD C C +GYQ G C D C+ G S E+ C
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES---CINT 236
Query: 200 TGLSDSYPPCCLSLGCWR----GVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTC 255
G S C R G G+ + S + C T
Sbjct: 237 VG----------SFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQN---TL 283
Query: 256 SGLTNRDCGECEVGWVLDE-GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG 314
R +C+ G++ D G C+D++EC + PC C N GSYTC++
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK------- 336
Query: 315 CTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG- 371
N C GY E +C DVDEC+ + C K C N+PGS+ C C G
Sbjct: 337 -------NVPNCGRGYHLNEEGTRCVDVDECAPPAEPC-GKGHRCVNSPGSFRCECKTGY 388
Query: 372 -FEETEDACVPPAEAEATEG 390
F+ CV E + G
Sbjct: 389 YFDGISRMCVDVNECQRYPG 408
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 42/145 (28%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSY----------------TCEE 307
C VG+ L D +C D++EC++ PCS Q C N GSY TCE+
Sbjct: 426 CSVGFRLSVDGRSCEDINECSSS--PCS--QECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 308 ------------CDSSCVGCTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRK 353
C C+ G +C SGY A C D+DEC C
Sbjct: 482 IDECALPTGGHICSYRCINIPGSFQCSCPS--SGYRLAPNGRNCQDIDECVTGIHNC-SI 538
Query: 354 NENCYNTPGSYVCV---CPDGFEET 375
NE C+N G + C+ CP+ + +
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRS 563
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/287 (23%), Positives = 94/287 (32%), Gaps = 57/287 (19%)
Query: 134 GPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCR----CHMGYQGPLCTDCMDGYFSSLR 189
G C+ G + C + C D SC+ C G L S R
Sbjct: 230 GESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 190 NETHSICTVRTG-LSDSYPPC-----CLSLGCWRGVGHAWIR--------------GRNT 229
C ++G + D+ C CLS+ +GH I GR
Sbjct: 288 CRPKLQC--KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 230 HTQPGYSSRVWIAAFSPACDESCK--TCSGLTNRDCGECEVGWVLD--EGACVDVDECAA 285
H + V + +P + K C EC+ G+ D CVDV+EC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 286 EPPPCSAAQFCKNANGSYTC------------------EECDSS-----CVGCTGEGPGN 322
P + C+N GSY C EC SS C G
Sbjct: 406 YPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCY 464
Query: 323 CKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCP 369
C+ + C D+DEC+L + + C N PGS+ C CP
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHI-CSYRCINIPGSFQCSCP 510
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 77.0 bits (188), Expect = 3e-14
Identities = 72/260 (27%), Positives = 95/260 (36%), Gaps = 48/260 (18%)
Query: 148 CSGNGHCSGDGSRQGDGS-CRCHMGYQ----GPLCTD---CMDGYFSSLRNETHSICTVR 199
C G G C GD C C +GYQ G C D C+ G S E+ C
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES---CINT 236
Query: 200 TGLSDSYPPCCLSLGCWR----GVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTC 255
G S C R G G+ + S + C T
Sbjct: 237 VG----------SFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQN---TL 283
Query: 256 SGLTNRDCGECEVGWVLDE-GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG 314
R +C+ G++ D G C+D++EC + PC C N GSYTC++
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK------- 336
Query: 315 CTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG- 371
N C GY E +C DVDEC+ + C K C N+PGS+ C C G
Sbjct: 337 -------NVPNCGRGYHLNEEGTRCVDVDECAPPAEPC-GKGHRCVNSPGSFRCECKTGY 388
Query: 372 -FEETEDACVPPAEAEATEG 390
F+ CV E + G
Sbjct: 389 YFDGISRMCVDVNECQRYPG 408
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 42/145 (28%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSY----------------TCEE 307
C VG+ L D +C D++EC++ PCS Q C N GSY TCE+
Sbjct: 426 CSVGFRLSVDGRSCEDINECSSS--PCS--QECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 308 ------------CDSSCVGCTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRK 353
C C+ G +C SGY A C D+DEC C
Sbjct: 482 IDECALPTGGHICSYRCINIPGSFQCSCPS--SGYRLAPNGRNCQDIDECVTGIHNC-SI 538
Query: 354 NENCYNTPGSYVCV---CPDGFEET 375
NE C+N G + C+ CP+ + +
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRS 563
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/287 (23%), Positives = 94/287 (32%), Gaps = 57/287 (19%)
Query: 134 GPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCR----CHMGYQGPLCTDCMDGYFSSLR 189
G C+ G + C + C D SC+ C G L S R
Sbjct: 230 GESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 190 NETHSICTVRTG-LSDSYPPC-----CLSLGCWRGVGHAWIR--------------GRNT 229
C ++G + D+ C CLS+ +GH I GR
Sbjct: 288 CRPKLQC--KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 230 HTQPGYSSRVWIAAFSPACDESCK--TCSGLTNRDCGECEVGWVLD--EGACVDVDECAA 285
H + V + +P + K C EC+ G+ D CVDV+EC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 286 EPPPCSAAQFCKNANGSYTC------------------EECDSS-----CVGCTGEGPGN 322
P + C+N GSY C EC SS C G
Sbjct: 406 YPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCY 464
Query: 323 CKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCP 369
C+ + C D+DEC+L + + C N PGS+ C CP
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHI-CSYRCINIPGSFQCSCP 510
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 77.0 bits (188), Expect = 3e-14
Identities = 72/260 (27%), Positives = 95/260 (36%), Gaps = 48/260 (18%)
Query: 148 CSGNGHCSGDGSRQGDGS-CRCHMGYQ----GPLCTD---CMDGYFSSLRNETHSICTVR 199
C G G C GD C C +GYQ G C D C+ G S E+ C
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGES---CINT 236
Query: 200 TGLSDSYPPCCLSLGCWR----GVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTC 255
G S C R G G+ + S + C T
Sbjct: 237 VG----------SFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQN---TL 283
Query: 256 SGLTNRDCGECEVGWVLDE-GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG 314
R +C+ G++ D G C+D++EC + PC C N GSYTC++
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK------- 336
Query: 315 CTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG- 371
N C GY E +C DVDEC+ + C K C N+PGS+ C C G
Sbjct: 337 -------NVPNCGRGYHLNEEGTRCVDVDECAPPAEPC-GKGHRCVNSPGSFRCECKTGY 388
Query: 372 -FEETEDACVPPAEAEATEG 390
F+ CV E + G
Sbjct: 389 YFDGISRMCVDVNECQRYPG 408
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 42/145 (28%)
Query: 266 CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSY----------------TCEE 307
C VG+ L D +C D++EC++ PCS Q C N GSY TCE+
Sbjct: 426 CSVGFRLSVDGRSCEDINECSSS--PCS--QECANVYGSYQCYCRRGYQLSDVDGVTCED 481
Query: 308 ------------CDSSCVGCTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRK 353
C C+ G +C SGY A C D+DEC C
Sbjct: 482 IDECALPTGGHICSYRCINIPGSFQCSCPS--SGYRLAPNGRNCQDIDECVTGIHNC-SI 538
Query: 354 NENCYNTPGSYVCV---CPDGFEET 375
NE C+N G + C+ CP+ + +
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRS 563
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/287 (23%), Positives = 94/287 (32%), Gaps = 57/287 (19%)
Query: 134 GPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCR----CHMGYQGPLCTDCMDGYFSSLR 189
G C+ G + C + C D SC+ C G L S R
Sbjct: 230 GESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFR 287
Query: 190 NETHSICTVRTG-LSDSYPPC-----CLSLGCWRGVGHAWIR--------------GRNT 229
C ++G + D+ C CLS+ +GH I GR
Sbjct: 288 CRPKLQC--KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGY 345
Query: 230 HTQPGYSSRVWIAAFSPACDESCK--TCSGLTNRDCGECEVGWVLD--EGACVDVDECAA 285
H + V + +P + K C EC+ G+ D CVDV+EC
Sbjct: 346 HLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQR 405
Query: 286 EPPPCSAAQFCKNANGSYTC------------------EECDSS-----CVGCTGEGPGN 322
P + C+N GSY C EC SS C G
Sbjct: 406 YPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCY 464
Query: 323 CKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCP 369
C+ + C D+DEC+L + + C N PGS+ C CP
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHI-CSYRCINIPGSFQCSCP 510
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 76.3 bits (186), Expect = 5e-14
Identities = 73/269 (27%), Positives = 97/269 (36%), Gaps = 67/269 (24%)
Query: 128 CSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGY-----QGPLCTDCMD 182
C PG Y D C R C+ N C GD C GY T C D
Sbjct: 674 CPPGHYHADKKRC-----RKCAPN--CESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPD 726
Query: 183 GYFSSLRN--------------ETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRN 228
G + + E H+ R GLS C S+ C G + G++
Sbjct: 727 GSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRC--SVSCEDG---RYFNGQD 781
Query: 229 THTQPGYSSRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPP 288
QP C C TC+G C C G+ +++G CV
Sbjct: 782 C--QP--------------CHRFCATCAGAGADGCINCTEGYFMEDGRCVQ--------- 816
Query: 289 PCSAAQFCKNA--NGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQ------CADV 340
CS + + ++ NG +C++CD SC+ C G G NC C SGY + G C D
Sbjct: 817 SCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMCQMGAICKDA 876
Query: 341 DECSLAEK---TCVRKNENCYNTPGSYVC 366
E S AE V+KN C +C
Sbjct: 877 TEESWAEGGFCMLVKKNNLCQRKVLQQLC 905
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 21/90 (23%)
Query: 308 CDSSC--VGCTGEGPGNCKECISGYAREHGQC-------------ADVDECSLAEKTCVR 352
CD C VGC G GP +C +C+ Y + AD C + C
Sbjct: 636 CDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHYHADKKRC----RKCAP 691
Query: 353 KNENCYNTPGSYVCVCPDGF--EETEDACV 380
E+C+ + G C G+ E ++CV
Sbjct: 692 NCESCFGSHGDQCMSCKYGYFLNEETNSCV 721
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 75.5 bits (184), Expect = 8e-14
Identities = 89/319 (27%), Positives = 115/319 (36%), Gaps = 76/319 (23%)
Query: 122 KTLKVCCSPGTYGPDCLACQGG--SQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTD 179
+T+ CC PD C S C G C GS Q C C G+QGP C
Sbjct: 105 RTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCV-PGSAQ---PCHCPPGFQGPRCQY 160
Query: 180 CMDGYFSSLRNETHS--------ICTVRTGL---SDSYPPCCLSL--------GCWRGVG 220
+D + H +C + G +DS CL++ GC
Sbjct: 161 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRT--CLAINSCALGNGGCQHHCV 218
Query: 221 HAWIRGRNTHTQPGYS---------SRVWIAAFSPACDESCKTCSGLTNRDCGECEVGWV 271
I +PG+ R A + +C C+ GL C EC VG+
Sbjct: 219 QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR--C-ECHVGYQ 275
Query: 272 L--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCE-------------------ECDS 310
L D AC DVDECAA C A C N GS+ C E +
Sbjct: 276 LAADGKACEDVDECAAGLAQC--AHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVN 333
Query: 311 SCV--------GCTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKTCVRKNENCYNT 360
SC GC+ G C GY + Q C DVD+C A+ C + + C N
Sbjct: 334 SCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDC--ADSPCCQ--QVCTNN 389
Query: 361 PGSYVCVCPDGFEETEDAC 379
PG Y C C G+ + D C
Sbjct: 390 PGGYECGCYAGYRLSADGC 408
Score = 64.3 bits (155), Expect = 2e-10
Identities = 72/268 (26%), Positives = 101/268 (37%), Gaps = 61/268 (22%)
Query: 147 PCSG-NGHCSGDGSR-QGDGSCRCHMGYQ----GPLCTDCMDGYFSSLRNETHSICTVRT 200
PC+ NG C +G C CH+GYQ G C D +
Sbjct: 247 PCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED---------------VDECAA 291
Query: 201 GLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCS-GLT 259
GL+ C + G ++ V HA G R+ + + +C+ + CS G +
Sbjct: 292 GLAQCAHGCLNTQGSFKCVCHA---GYELGADGRQCYRIEMEIVN-SCEANNGGCSHGCS 347
Query: 260 NRDCGE---CEVGWVLD--EGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVG 314
+ G C G+ LD + C+DVD+CA P Q C N G Y C
Sbjct: 348 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP---CCQQVCTNNPGGYECG-------- 396
Query: 315 CTGEGPGNCKECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C +GY + + C DVDEC+ + C +C N GS+ C C G+
Sbjct: 397 -----------CYAGYRLSADGCGCEDVDECASSRGGC---EHHCTNLAGSFQCSCEAGY 442
Query: 373 EETED--ACVPPAEAEA-TEGESPTQLP 397
ED C P E +GE P P
Sbjct: 443 RLHEDRRGCSPLEEPMVDLDGELPFVRP 470
Score = 49.7 bits (117), Expect = 5e-06
Identities = 72/274 (26%), Positives = 96/274 (35%), Gaps = 62/274 (22%)
Query: 128 CSPGTYGPDCL-ACQGGSQRP-CSGNGHCS-GDGSRQG-DGSCRCHMGYQGPLC-TDCMD 182
C+PG G C AC G P CS +CS G GS G C C GY GP C C
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQ 906
Query: 183 GYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIA 242
G+F P C C G + G T W
Sbjct: 907 GHFG--------------------PGCEQRCQCQHGAACDHVSGACT------CPAGWRG 940
Query: 243 AFSPACDESCKT-CSGLTNRDCGECEVGWVLD--EGACV---------DVDECAAEPPPC 290
F C+ +C GL R C G D G+C+ + C A
Sbjct: 941 TF---CEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGH 997
Query: 291 SAAQFCKNANGSYTCEECDSSCVGCTG-EGPGNCKECISGYAREHGQCADVDECSLAEKT 349
+ +Q C NG+ +C+ C G GP + C +G +G D C +
Sbjct: 998 NCSQACACFNGA-SCDPVHGQCHCAPGWMGPSCLQACPAGL---YG-----DNC---RHS 1045
Query: 350 CVRKNENCYNTPGSYVCVCPDGFE--ETEDACVP 381
C+ +N + P S C CP+G+ E C+P
Sbjct: 1046 CLCQNGGTCD-PVSGHCACPEGWAGLACEKECLP 1078
Score = 45.8 bits (107), Expect = 7e-05
Identities = 60/223 (26%), Positives = 78/223 (34%), Gaps = 39/223 (17%)
Query: 128 CSPGTYGPDC-LACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTD-CMDGYF 185
C P T+G +C +C C G C G+CRC G G C D C GY+
Sbjct: 555 CPPDTFGKNCSFSCS------CQNGGTCDSV-----TGACRCPPGVSGTNCEDGCPKGYY 603
Query: 186 SS-LRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGH----AWIRGRNTHTQPGYSSRV- 239
R + + C R Y C G + H W G PG S
Sbjct: 604 GKHCRKKCN--CANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFG------PGCSEECQ 655
Query: 240 WIAAFSPACDE---SCKTCSGLTNRDC-GECEVGWVLDEGACVDVDECAAEPPPCSAAQF 295
+ + +CD+ SC +G C ECE+G+ C C S +
Sbjct: 656 CVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYF--GPGCWQACTCPVGVACDSVSGE 713
Query: 296 C-KNANGSYTCEECDSSC-VGCTGEGPGNC-KECISGYAREHG 335
C K + E+C C VG G NC C G A HG
Sbjct: 714 CGKRCPAGFQGEDCGQECPVGTFGV---NCSSSCSCGGAPCHG 753
Score = 45.8 bits (107), Expect = 7e-05
Identities = 67/294 (22%), Positives = 102/294 (34%), Gaps = 76/294 (25%)
Query: 128 CSPGTYGPDCL-ACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFS 186
C G +G DC AC C+ C +GSC C G +GP C +
Sbjct: 947 CPAGFFGLDCRSACN------CTAGAACDAV-----NGSCLCPAGRRGPRCAE------- 988
Query: 187 SLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSP 246
C T + C + C+ G + G+ H PG+ P
Sbjct: 989 --------TCPAHTYGHN----CSQACACFNGASCDPVHGQ-CHCAPGW--------MGP 1027
Query: 247 ACDESCKTCSGLTNRDCGE---CEVGWVLD--EGACVDVD-----ECAAEPPPCSAAQFC 296
+C ++C +GL +C C+ G D G C + C E P C
Sbjct: 1028 SCLQACP--AGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGC 1085
Query: 297 KNANGSYTCEECD---SSCVGCTGEGPGNCKE-CISGYAREHGQCADVDECSLAEKTCVR 352
+++ G CD C+ G C+ C+ G+ E + A++
Sbjct: 1086 RHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGE----------ACAQRCSCP 1135
Query: 353 KNENCYNTPGSYVCVCPDGFEET--EDACVPPAEAE------ATEGESPTQLPS 398
C++ G+ C CP GF + E AC P + E GE+P P+
Sbjct: 1136 PGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPA 1187
Score = 45.4 bits (106), Expect = 9e-05
Identities = 72/271 (26%), Positives = 91/271 (33%), Gaps = 60/271 (22%)
Query: 128 CSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCT-DCMDGYFS 186
C PG YGP C G C G C G+CRC G+ G C C G F
Sbjct: 1206 CPPGRYGPGCEQLCG-----CLNGGSCDA-----ATGACRCPTGFLGTDCNLTCPQGRFG 1255
Query: 187 SLRNETHSICTVRTGLS-DSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFS 245
N TH +C G + D CL G A +R Q F
Sbjct: 1256 P--NCTH-VCGCGQGAACDPVTGTCLC-----PPGRAGVRCERGCPQ---------NRFG 1298
Query: 246 PACDESCKTCSG----LTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCK---N 298
C+ +C +G +N C C +GW C PP C +
Sbjct: 1299 VGCEHTCSCRNGGLCHASNGSC-SCGLGWT--------GRHCELACPPGRYGAACHLECS 1349
Query: 299 ANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTC-VRKNENC 357
+ + TCE +C C GPG G A EH C + + C + C
Sbjct: 1350 CHNNSTCEPATGTC-RC---GPG-----FYGQACEH-PCPPGFHGAGCQGLCWCQHGAPC 1399
Query: 358 YNTPGSYVCVCPDGFEE--TEDACVPPAEAE 386
P S C+CP GF E C P + E
Sbjct: 1400 --DPISGRCLCPAGFHGHFCERGCEPGSFGE 1428
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/201 (24%), Positives = 65/201 (32%), Gaps = 54/201 (26%)
Query: 120 CVKTLKVC-CSPGTYGPDC-LACQGGSQRP-CSGNGHCSGDGSR---QGDGSCRCHMGYQ 173
C + C C PG YG C L C + P CS C ++ + DGSC C G++
Sbjct: 619 CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFR 678
Query: 174 GPLC-TDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQ 232
G C +C GYF P C + C GV + G
Sbjct: 679 GERCQAECELGYFG--------------------PGCWQACTCPVGVACDSVSGE----- 713
Query: 233 PGYSSRVWIAAFSPACDESCKTCSGLTNRDCG-ECEVGWVLDEGACVDVDECAAEPPPCS 291
C + C +G DCG EC VG C+ PC
Sbjct: 714 ---------------CGKRCP--AGFQGEDCGQECPVGTF----GVNCSSSCSCGGAPCH 752
Query: 292 AAQFCKNANGSYTCEECDSSC 312
T E+C++ C
Sbjct: 753 GVTGQCRCPPGRTGEDCEADC 773
Score = 39.7 bits (91), Expect = 0.005
Identities = 75/300 (25%), Positives = 94/300 (31%), Gaps = 55/300 (18%)
Query: 103 AWWLQLKSEYPDLFEWF---------------CVKTLKVC-CSPGTYGPDC-LACQGGS- 144
A W K + P L WF C C C PG G C AC GS
Sbjct: 1108 AGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSF 1167
Query: 145 QRPCSGNGHCSGDGS--RQGDGSCRCHMGYQGPLCTD-CMDGYFSSLRNETHSICTVRTG 201
C+ C G+ G+C C GY GP C C G + +C G
Sbjct: 1168 GEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP---GCEQLCGCLNG 1224
Query: 202 LSDSYPPCCLSLG-CWRGVGHAWIRGRNTHTQPGYS---SRVWIAAFSPACDESCKTCSG 257
S C + G C G T Q + + V ACD TC
Sbjct: 1225 GS-----CDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLC 1279
Query: 258 LTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTG 317
R CE G + C+ C C +NGS +C +G TG
Sbjct: 1280 PPGRAGVRCERGCPQNRFGVGCEHTCS-----CRNGGLCHASNGSCSCG------LGWTG 1328
Query: 318 EGPGNCK-ECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSY--VC--VCPDGF 372
+C+ C G +G ++ TC C PG Y C CP GF
Sbjct: 1329 R---HCELACPPG---RYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGF 1382
Score = 36.2 bits (82), Expect = 0.054
Identities = 65/238 (27%), Positives = 81/238 (34%), Gaps = 65/238 (27%)
Query: 125 KVCCSPGTYGPDC-LACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCT-DCMD 182
++ C PG YG C L C C N C G+CRC G+ G C C
Sbjct: 1332 ELACPPGRYGAACHLECS------CHNNSTC-----EPATGTCRCGPGFYGQACEHPCPP 1380
Query: 183 GYFSSLRNETHSICTVRTGL-SDSYPPCCLSLGCWRGV-GHAWIRGRNTHTQPGYSSRVW 240
G+ + +C + G D CL C G GH RG +PG
Sbjct: 1381 GFHGA---GCQGLCWCQHGAPCDPISGRCL---CPAGFHGHFCERG----CEPG------ 1424
Query: 241 IAAFSPACDESCKTCSGLTNRDCGECEVGWVLDEGA-CVDVDECAAEPPPCSAAQF---C 296
+F C + C DC D GA C V PP S A C
Sbjct: 1425 --SFGEGCHQRC---------DC---------DGGAPCDPVTGLCLCPPGRSGATCNLDC 1464
Query: 297 KNANGSYTCE-ECDSSCVGCTGEGP--GNCKECISGY----AREHGQCADVDECSLAE 347
+ +C CD C G P G C C+ GY RE G + SLA+
Sbjct: 1465 RRGQFGPSCTLHCD--CGGGADCDPVSGQC-HCVDGYMGPTCREGGPLRLPENPSLAQ 1519
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 74.3 bits (181), Expect = 2e-13
Identities = 41/129 (31%), Positives = 60/129 (46%), Gaps = 24/129 (18%)
Query: 266 CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKE 325
CE G+ L +G C DVDECA C C+N GS+ C+ +
Sbjct: 751 CEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA---------------RQR 795
Query: 326 CISGYARE-HGQCADVDECSLAEKTCVRKNENCYNTPGSYVC-----VCPDGFEETEDA- 378
C+ G+ ++ G C D++EC+ + C R +C NT GSY C +C G+ ++D
Sbjct: 796 CMDGFLQDPEGNCVDINECTSLSEPC-RPGFSCINTVGSYTCQRNPLICARGYHASDDGT 854
Query: 379 -CVPPAEAE 386
CV E E
Sbjct: 855 KCVDVNECE 863
Score = 68.9 bits (167), Expect = 8e-12
Identities = 45/140 (32%), Positives = 64/140 (45%), Gaps = 26/140 (18%)
Query: 248 CDESCKTCSGLTNRDCGECEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTC 305
C + C T G + C C G+ + D +C D++EC + CS + C N GS+ C
Sbjct: 689 CKQVCSTVGG--SAICS-CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHC 745
Query: 306 EECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYV 365
+ C GYA + G+C DVDEC++ TC + C NT GS+
Sbjct: 746 YK---------------ALTCEPGYALKDGECEDVDECAMGTHTC-QPGFLCQNTKGSFY 789
Query: 366 CV----CPDGF-EETEDACV 380
C C DGF ++ E CV
Sbjct: 790 CQARQRCMDGFLQDPEGNCV 809
Score = 58.2 bits (139), Expect = 1e-08
Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 41/224 (18%)
Query: 180 CMDGYFSSLRNETHSICTVRTGLSDSYPP---CCLSLGCWRGVGHAWIRGRNTHTQPGYS 236
CMDG+ I T LS+ P C ++G + + I R H +
Sbjct: 796 CMDGFLQDPEGNCVDINEC-TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT 854
Query: 237 SRVWIAAFSPA---CDESCKTCSGLTNRDCGECEVGWVLDE--GACVDVDECAAEPPPCS 291
V + C E + C L +C+ G+ D C+DV+EC A P
Sbjct: 855 KCVDVNECETGVHRCGEG-QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL- 912
Query: 292 AAQFCKNANGSYTC-----------------------EECDSSCVGCTGEGPGNCKECIS 328
C+N GSY C + C C G C++
Sbjct: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQ--- 969
Query: 329 GY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPD 370
GY A + C D+DEC A+ + C N PGSY C CP+
Sbjct: 970 GYQLAEDGHTCTDIDEC--AQGAGILCTFRCLNVPGSYQCACPE 1011
Score = 56.6 bits (135), Expect = 4e-08
Identities = 42/131 (32%), Positives = 56/131 (42%), Gaps = 31/131 (23%)
Query: 273 DEGA-CVDVDECAAEPPPCSAAQFCKNANGSYTCE-----ECDSSCVGCTG-----EGPG 321
D+G CVDV+EC C Q C N GSY C+ + D+ GC PG
Sbjct: 851 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPG 910
Query: 322 N-CK------------ECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVC 366
C+ C SG+ A + +C DV+EC R ++ C N GSY C
Sbjct: 911 RLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE-----AQRCSQECANIYGSYQC 965
Query: 367 VCPDGFEETED 377
C G++ ED
Sbjct: 966 YCRQGYQLAED 976
Score = 52.0 bits (123), Expect = 9e-07
Identities = 60/248 (24%), Positives = 92/248 (37%), Gaps = 53/248 (21%)
Query: 148 CSGNGHCSGDGSRQGDGSCRCHMGY----QGPLCTDCMDGYFSSLRNETHSICTVRTGLS 203
C+ H S DG++ D + C G +G +C + Y C + G
Sbjct: 843 CARGYHASDDGTKCVDVN-ECETGVHRCGEGQVCHNLPGSYR----------CDCKAGFQ 891
Query: 204 -DSYPPCCLSLG-CWRGVGHAWIRGRNTHTQPGY----SSRVWIAAFSPACDESCKTCSG 257
D++ C+ + CW G + +T Y +S +AA C++ + +
Sbjct: 892 RDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ 950
Query: 258 LTNRDCGE--------CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTCEE 307
+++C C G+ L E C D+DECA + C N GSY C
Sbjct: 951 RCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFR-CLNVPGSYQCA- 1008
Query: 308 CDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCV 367
C T G C DVDEC+L C + E C+N GS+ C+
Sbjct: 1009 CPEQGYTMTANGRS---------------CKDVDECALGTHNC-SEAETCHNIQGSFRCL 1052
Query: 368 ---CPDGF 372
CP +
Sbjct: 1053 RFECPPNY 1060
Score = 32.3 bits (72), Expect = 0.78
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 339 DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQ 395
D DEC L + C NT GSY C C GF +D E + E+P +
Sbjct: 604 DQDECLLLPGELCQ--HLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE 658
Score = 30.4 bits (67), Expect = 3.0
Identities = 41/154 (26%), Positives = 60/154 (38%), Gaps = 28/154 (18%)
Query: 266 CEVG--WVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEE-CDSSCVG------CT 316
C G W +D C+++ E E C AQ ++ SY E+ C + +G C
Sbjct: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQ--RHCCVSYLQEKSCMAGVLGAKEGETCG 503
Query: 317 GEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPG-SYVC-----VCPD 370
E +C IS Y QC D C L + + ++C + P Y C C +
Sbjct: 504 AEDNDSCG--ISLYK----QCCDC--CGLGLRVRA-EGQSCESNPNLGYPCNHVMLSCCE 554
Query: 371 GFEE--TEDACVPPAEAEATEGESPTQLPSREDL 402
G E + PP A A S ++ RE L
Sbjct: 555 GEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREAL 588
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 74.3 bits (181), Expect = 2e-13
Identities = 41/129 (31%), Positives = 60/129 (46%), Gaps = 24/129 (18%)
Query: 266 CEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKE 325
CE G+ L +G C DVDECA C C+N GS+ C+ +
Sbjct: 798 CEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA---------------RQR 842
Query: 326 CISGYARE-HGQCADVDECSLAEKTCVRKNENCYNTPGSYVC-----VCPDGFEETEDA- 378
C+ G+ ++ G C D++EC+ + C R +C NT GSY C +C G+ ++D
Sbjct: 843 CMDGFLQDPEGNCVDINECTSLSEPC-RPGFSCINTVGSYTCQRNPLICARGYHASDDGT 901
Query: 379 -CVPPAEAE 386
CV E E
Sbjct: 902 KCVDVNECE 910
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/172 (31%), Positives = 73/172 (42%), Gaps = 43/172 (25%)
Query: 248 CDESCKTCSGLTNRDCGECEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNANGSYTC 305
C + C T G + C C G+ + D +C D DEC CS QFC N GS+ C
Sbjct: 689 CKQVCSTVGG--SAICS-CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYC 745
Query: 306 ----------------------EECDSSCVGCT-GE------GPGNCKE---CISGYARE 333
EC + C+ GE G +C + C GYA +
Sbjct: 746 VNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK 805
Query: 334 HGQCADVDECSLAEKTCVRKNENCYNTPGSYVCV----CPDGF-EETEDACV 380
G+C DVDEC++ TC + C NT GS+ C C DGF ++ E CV
Sbjct: 806 DGECEDVDECAMGTHTC-QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV 856
Score = 58.2 bits (139), Expect = 1e-08
Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 41/224 (18%)
Query: 180 CMDGYFSSLRNETHSICTVRTGLSDSYPP---CCLSLGCWRGVGHAWIRGRNTHTQPGYS 236
CMDG+ I T LS+ P C ++G + + I R H +
Sbjct: 843 CMDGFLQDPEGNCVDINEC-TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT 901
Query: 237 SRVWIAAFSPA---CDESCKTCSGLTNRDCGECEVGWVLDE--GACVDVDECAAEPPPCS 291
V + C E + C L +C+ G+ D C+DV+EC A P
Sbjct: 902 KCVDVNECETGVHRCGEG-QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL- 959
Query: 292 AAQFCKNANGSYTC-----------------------EECDSSCVGCTGEGPGNCKECIS 328
C+N GSY C + C C G C++
Sbjct: 960 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQ--- 1016
Query: 329 GY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPD 370
GY A + C D+DEC A+ + C N PGSY C CP+
Sbjct: 1017 GYQLAEDGHTCTDIDEC--AQGAGILCTFRCLNVPGSYQCACPE 1058
Score = 56.6 bits (135), Expect = 4e-08
Identities = 42/131 (32%), Positives = 56/131 (42%), Gaps = 31/131 (23%)
Query: 273 DEGA-CVDVDECAAEPPPCSAAQFCKNANGSYTCE-----ECDSSCVGCTG-----EGPG 321
D+G CVDV+EC C Q C N GSY C+ + D+ GC PG
Sbjct: 898 DDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPG 957
Query: 322 N-CK------------ECISGY--AREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVC 366
C+ C SG+ A + +C DV+EC R ++ C N GSY C
Sbjct: 958 RLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE-----AQRCSQECANIYGSYQC 1012
Query: 367 VCPDGFEETED 377
C G++ ED
Sbjct: 1013 YCRQGYQLAED 1023
Score = 52.0 bits (123), Expect = 9e-07
Identities = 60/248 (24%), Positives = 92/248 (37%), Gaps = 53/248 (21%)
Query: 148 CSGNGHCSGDGSRQGDGSCRCHMGY----QGPLCTDCMDGYFSSLRNETHSICTVRTGLS 203
C+ H S DG++ D + C G +G +C + Y C + G
Sbjct: 890 CARGYHASDDGTKCVDVN-ECETGVHRCGEGQVCHNLPGSYR----------CDCKAGFQ 938
Query: 204 -DSYPPCCLSLG-CWRGVGHAWIRGRNTHTQPGY----SSRVWIAAFSPACDESCKTCSG 257
D++ C+ + CW G + +T Y +S +AA C++ + +
Sbjct: 939 RDAFGRGCIDVNECWASPGRL-CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ 997
Query: 258 LTNRDCGE--------CEVGWVLDEGA--CVDVDECAAEPPPCSAAQFCKNANGSYTCEE 307
+++C C G+ L E C D+DECA + C N GSY C
Sbjct: 998 RCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFR-CLNVPGSYQCA- 1055
Query: 308 CDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCV 367
C T G C DVDEC+L C + E C+N GS+ C+
Sbjct: 1056 CPEQGYTMTANGRS---------------CKDVDECALGTHNC-SEAETCHNIQGSFRCL 1099
Query: 368 ---CPDGF 372
CP +
Sbjct: 1100 RFECPPNY 1107
Score = 32.3 bits (72), Expect = 0.78
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 339 DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQ 395
D DEC L + C NT GSY C C GF +D E + E+P +
Sbjct: 604 DQDECLLLPGELCQ--HLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE 658
Score = 30.4 bits (67), Expect = 3.0
Identities = 41/154 (26%), Positives = 60/154 (38%), Gaps = 28/154 (18%)
Query: 266 CEVG--WVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEE-CDSSCVG------CT 316
C G W +D C+++ E E C AQ ++ SY E+ C + +G C
Sbjct: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQ--RHCCVSYLQEKSCMAGVLGAKEGETCG 503
Query: 317 GEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPG-SYVC-----VCPD 370
E +C IS Y QC D C L + + ++C + P Y C C +
Sbjct: 504 AEDNDSCG--ISLYK----QCCDC--CGLGLRVRA-EGQSCESNPNLGYPCNHVMLSCCE 554
Query: 371 GFEE--TEDACVPPAEAEATEGESPTQLPSREDL 402
G E + PP A A S ++ RE L
Sbjct: 555 GEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREAL 588
>gi|75709198 nephronectin [Homo sapiens]
Length = 565
Score = 74.3 bits (181), Expect = 2e-13
Identities = 67/245 (27%), Positives = 81/245 (33%), Gaps = 50/245 (20%)
Query: 140 CQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTVR 199
CQ Q C +G C G C+CH GY G C ++ R H C
Sbjct: 56 CQPVCQPRCK-HGECIGPNK------CKCHPGYAGKTCNQDLNECGLKPRPCKHR-CMNT 107
Query: 200 TGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGLT 259
G SY CL+ P S + C C G
Sbjct: 108 YG---SYKCYCLN---------------GYMLMPDGSCSSALTCSMANCQYGCDVVKGQI 149
Query: 260 NRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEG 319
C + D CVDVDECA C + C N GSY C
Sbjct: 150 RCQCPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYIC-------------- 195
Query: 320 PGNCKECISG----YAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEET 375
+C G Y QC D+DECSL + C CYN GSY C C +G++
Sbjct: 196 -----KCHKGFDLMYIGGKYQCHDIDECSLGQYQC-SSFARCYNIRGSYKCKCKEGYQGD 249
Query: 376 EDACV 380
CV
Sbjct: 250 GLTCV 254
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 73.9 bits (180), Expect = 2e-13
Identities = 86/293 (29%), Positives = 112/293 (38%), Gaps = 76/293 (25%)
Query: 95 EAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHC 154
E ++ ++ + K + PD+F+W G+ GP C++ + G NG C
Sbjct: 227 EGDKDETQSHYFLCKEKAPDVFDW------------GSSGPLCVSPKYGCN---FNNGGC 271
Query: 155 SGDGSRQGDGS--CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTVRTGLSDSYPPCCLS 212
D GDGS C C G++ L D + C R S S PC
Sbjct: 272 HQDCFEGGDGSFLCGCRPGFR--LLDDLVT-------------CASRNPCSSS--PCRGG 314
Query: 213 LGCWRGVGHAWIRGRN--THTQPGY---SSRVWIAAFSPACDESC-KTCSGLTNRDCGEC 266
C G G+N GY SS++ D C + C EC
Sbjct: 315 ATCVLGP-----HGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCEC 369
Query: 267 EVGWVLD---EGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNC 323
VG+ EGAC DVDECA PC AQ C N +GS+ C
Sbjct: 370 WVGYEPGGPGEGACQDVDECALGRSPC--AQGCTNTDGSFHC------------------ 409
Query: 324 KECISGY--AREHG-QCADVDEC-SLAEKTCVRKNENCYNTPGSYVCVCPDGF 372
C GY A E G QC DVDEC C + C+NT GS+ C C G+
Sbjct: 410 -SCEEGYVLAGEDGTQCQDVDECVGPGGPLC---DSLCFNTQGSFHCGCLPGW 458
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/135 (26%), Positives = 50/135 (37%), Gaps = 37/135 (27%)
Query: 252 CKTCSGLTNRDCGE---------CEVGWVL--DEGACVDVDECAAEPPPCSAAQFCKNAN 300
C +G ++DC E C G+ L D C + C++ P A
Sbjct: 264 CNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHG 323
Query: 301 GSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQ--CADVDECSLAEKTCVRKNENCY 358
+YTC C GY + Q C DVDEC + C ++ C
Sbjct: 324 KNYTCR-------------------CPQGYQLDSSQLDCVDVDECQ--DSPCAQE---CV 359
Query: 359 NTPGSYVCVCPDGFE 373
NTPG + C C G+E
Sbjct: 360 NTPGGFRCECWVGYE 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.463
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,901,075
Number of Sequences: 37866
Number of extensions: 1151862
Number of successful extensions: 9761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 6403
Number of HSP's gapped (non-prelim): 1895
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.