Search of human proteins with 20336290

Search of human proteins with 20336290

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
[Homo sapiens]
         (1155 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ...  2296   0.0  
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ...  2292   0.0  
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1...   496   e-140
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2...   471   e-132
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...   424   e-118
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...   405   e-112
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi...   311   3e-84
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]   280   7e-75
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]    270   4e-72
gi|166851804 tudor domain containing 9 [Homo sapiens]                 267   4e-71
gi|38505213 YTH domain containing 2 [Homo sapiens]                    261   2e-69
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...   256   1e-67
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi...   251   3e-66
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...   251   4e-66
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi...   246   1e-64
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi...   241   4e-63
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi...   238   2e-62
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po...   216   1e-55
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom...   149   2e-35
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo...   141   4e-33
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi...   124   7e-28
gi|4885615 signal transducer and activator of transcription 2 [H...    39   0.029
gi|4758532 ral guanine nucleotide dissociation stimulator-like 2...    37   0.083
gi|32455236 helicase (DNA) B [Homo sapiens]                            37   0.083
gi|149408122 RNA helicase LGP2 [Homo sapiens]                          37   0.11 
gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]    37   0.14 
gi|145309298 coiled-coil domain containing 16 [Homo sapiens]           35   0.32 
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...    35   0.41 
gi|21735569 claspin [Homo sapiens]                                     34   0.70 
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [...    34   0.70 

>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
            sapiens]
          Length = 1155

 Score = 2296 bits (5949), Expect = 0.0
 Identities = 1155/1155 (100%), Positives = 1155/1155 (100%)

Query: 1    MAASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEV 60
            MAASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEV
Sbjct: 1    MAASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEV 60

Query: 61   EGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPT 120
            EGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPT
Sbjct: 61   EGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPT 120

Query: 121  MPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPL 180
            MPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPL
Sbjct: 121  MPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPL 180

Query: 181  RDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLST 240
            RDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLST
Sbjct: 181  RDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLST 240

Query: 241  LTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELG 300
            LTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELG
Sbjct: 241  LTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELG 300

Query: 301  ETQRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITG 360
            ETQRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITG
Sbjct: 301  ETQRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITG 360

Query: 361  KPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDT 420
            KPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDT
Sbjct: 361  KPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDT 420

Query: 421  GCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQV 480
            GCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQV
Sbjct: 421  GCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQV 480

Query: 481  RLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQ 540
            RLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQ
Sbjct: 481  RLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQ 540

Query: 541  RLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRH 600
            RLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRH
Sbjct: 541  RLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRH 600

Query: 601  RHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKY 660
            RHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKY
Sbjct: 601  RHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKY 660

Query: 661  LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDL 720
            LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDL
Sbjct: 661  LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDL 720

Query: 721  KTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENL 780
            KTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENL
Sbjct: 721  KTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENL 780

Query: 781  VLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHIST 840
            VLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHIST
Sbjct: 781  VLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHIST 840

Query: 841  DPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAF 900
            DPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAF
Sbjct: 841  DPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAF 900

Query: 901  VRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCT 960
            VRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCT
Sbjct: 901  VRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCT 960

Query: 961  LASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHK 1020
            LASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHK
Sbjct: 961  LASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHK 1020

Query: 1021 STINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATIS 1080
            STINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATIS
Sbjct: 1021 STINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATIS 1080

Query: 1081 LSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELL 1140
            LSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELL
Sbjct: 1081 LSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELL 1140

Query: 1141 RGPCGSFDVRKTADD 1155
            RGPCGSFDVRKTADD
Sbjct: 1141 RGPCGSFDVRKTADD 1155


>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
            sapiens]
          Length = 1194

 Score = 2292 bits (5940), Expect = 0.0
 Identities = 1153/1153 (100%), Positives = 1153/1153 (100%)

Query: 3    ASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEG 62
            ASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEG
Sbjct: 42   ASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEG 101

Query: 63   YGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMP 122
            YGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMP
Sbjct: 102  YGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMP 161

Query: 123  PTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRD 182
            PTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRD
Sbjct: 162  PTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRD 221

Query: 183  SRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLT 242
            SRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLT
Sbjct: 222  SRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLT 281

Query: 243  LLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGET 302
            LLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGET
Sbjct: 282  LLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGET 341

Query: 303  QRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKP 362
            QRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKP
Sbjct: 342  QRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKP 401

Query: 363  YVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGC 422
            YVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGC
Sbjct: 402  YVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGC 461

Query: 423  GKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRL 482
            GKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRL
Sbjct: 462  GKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRL 521

Query: 483  ESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRL 542
            ESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRL
Sbjct: 522  ESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRL 581

Query: 543  NPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRH 602
            NPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRH
Sbjct: 582  NPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRH 641

Query: 603  HESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLI 662
            HESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLI
Sbjct: 642  HESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLI 701

Query: 663  LPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKT 722
            LPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKT
Sbjct: 702  LPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKT 761

Query: 723  KVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVL 782
            KVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVL
Sbjct: 762  KVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVL 821

Query: 783  QAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDP 842
            QAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDP
Sbjct: 822  QAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDP 881

Query: 843  RLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVR 902
            RLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVR
Sbjct: 882  RLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVR 941

Query: 903  AVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLA 962
            AVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLA
Sbjct: 942  AVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLA 1001

Query: 963  SAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKST 1022
            SAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKST
Sbjct: 1002 SAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKST 1061

Query: 1023 INREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLS 1082
            INREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLS
Sbjct: 1062 INREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLS 1121

Query: 1083 DSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLRG 1142
            DSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLRG
Sbjct: 1122 DSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLRG 1181

Query: 1143 PCGSFDVRKTADD 1155
            PCGSFDVRKTADD
Sbjct: 1182 PCGSFDVRKTADD 1194


>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
            [Homo sapiens]
          Length = 1008

 Score =  496 bits (1277), Expect = e-140
 Identities = 283/776 (36%), Positives = 443/776 (57%), Gaps = 71/776 (9%)

Query: 394  QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 453
            +LP    +  ++N I+ H V VISG+TGCGKTT++ Q +L+ Y+  G+G+ C ++ TQPR
Sbjct: 206  KLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPR 265

Query: 454  RISAVSVAQRVSHELGPSLR--RNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSL 511
            RISA+SVA+RV+ E   S     + G+Q+RL+S+ P + G++L+CT GI+L+ LQS+P L
Sbjct: 266  RISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYL 325

Query: 512  EGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIK 571
              VSH+++DE+HER++ +D L+ ++K L      L+++LMSAT + E+FS YFG CP+I 
Sbjct: 326  SSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIH 385

Query: 572  VPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESE------------------------- 606
            +PGF +PV E+ LED++ K+   +Y+   + H S+                         
Sbjct: 386  IPGFTFPVVEYLLEDVIEKI---RYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442

Query: 607  -----------------------DECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK 643
                                   ++  +DL+L+  L+ +I    E G IL FLPGW  I 
Sbjct: 443  WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502

Query: 644  GVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITIND 703
             +   L   +     K+LI+P+HS +P ++Q  +F++ P GVRKIV+ATNIAETSITI+D
Sbjct: 503  TLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDD 562

Query: 704  IVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEK 763
            +V+V+D G  KE  +D +  +S +   WVS+AN  QR+GRAGR Q G  YHL+   R   
Sbjct: 563  VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASL 622

Query: 764  MVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLD 823
            +  +Q+PEILRTPLE L LQ KI      A  FLS+ +D P+ +AV  ++  L E+  LD
Sbjct: 623  LDDYQLPEILRTPLEELCLQIKILRLGGIAY-FLSRLMDPPSNEAVLLSIRHLMELNALD 681

Query: 824  QREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEV 882
            ++E LT LG  LA +  +P + K I+  A+F CL P+L + + L+ +DPF   L      
Sbjct: 682  KQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIA 741

Query: 883  DKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQ 942
            D  +  L+ D+ SDHL  V A  GWEE  R   R  ++ Y  E  L + +L+ +H +  Q
Sbjct: 742  DARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKD-YCWEYFLSSNTLQMLHNMKGQ 800

Query: 943  FSENIYEAFLVG--KPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQG 1000
            F+E++  A  V    P D      + N  S+ E+++K V+ AGLYP + ++R       G
Sbjct: 801  FAEHLLGAGFVSSRNPKD-----PESNINSDNEKIIKAVICAGLYPKVAKIR----LNLG 851

Query: 1001 KFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAV 1060
            K +     Y    G + +H  ++N E T     WL Y + ++++ S+++ D ++V P   
Sbjct: 852  KKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTS-SIYLYDCTEVSPYC- 909

Query: 1061 LLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1116
            LL   GD+ I+ D  + TI++   + +  +  +R   L+KELR+ L  +++  + S
Sbjct: 910  LLFFGGDISIQKDNDQETIAV--DEWIVFQSPARIAHLVKELRKELDILLQEKIES 963


>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
            [Homo sapiens]
          Length = 994

 Score =  471 bits (1212), Expect = e-132
 Identities = 278/776 (35%), Positives = 435/776 (56%), Gaps = 85/776 (10%)

Query: 394  QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 453
            +LP    +  ++N I+ H V VISG+TGCGKTT++ Q +L+ Y+  G+G+ C ++ TQPR
Sbjct: 206  KLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPR 265

Query: 454  RISAVSVAQRVSHELGPSLR--RNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSL 511
            RISA+SVA+RV+ E   S     + G+Q+RL+S+ P + G++L+CT GI+L+ LQS+P L
Sbjct: 266  RISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYL 325

Query: 512  EGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIK 571
              VSH+++DE+HER++ +D L+ ++K L      L+++LMSAT + E+FS YFG CP+I 
Sbjct: 326  SSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIH 385

Query: 572  VPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESE------------------------- 606
            +PGF +PV E+ LED++ K+   +Y+   + H S+                         
Sbjct: 386  IPGFTFPVVEYLLEDVIEKI---RYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEAIYKER 442

Query: 607  -----------------------DECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK 643
                                   ++  +DL+L+  L+ +I    E G IL FLPGW  I 
Sbjct: 443  WPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNIS 502

Query: 644  GVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITIND 703
             +   L   + M +S             ++Q  +F++ P GVRKIV+ATNIAETSITI+D
Sbjct: 503  TLHDLLMSQV-MFKS-------------VNQTQVFKRTPPGVRKIVIATNIAETSITIDD 548

Query: 704  IVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEK 763
            +V+V+D G  KE  +D +  +S +   WVS+AN  QR+GRAGR Q G  YHL+   R   
Sbjct: 549  VVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASL 608

Query: 764  MVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLD 823
            +  +Q+PEILRTPLE L LQ KI      A  FLS+ +D P+ +AV  ++  L E+  LD
Sbjct: 609  LDDYQLPEILRTPLEELCLQIKILRLGGIAY-FLSRLMDPPSNEAVLLSIRHLMELNALD 667

Query: 824  QREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEV 882
            ++E LT LG  LA +  +P + K I+  A+F CL P+L + + L+ +DPF   L      
Sbjct: 668  KQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIA 727

Query: 883  DKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQ 942
            D  +  L+ D+ SDHL  V A  GWEE  R   R  ++ Y  E  L + +L+ +H +  Q
Sbjct: 728  DARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKD-YCWEYFLSSNTLQMLHNMKGQ 786

Query: 943  FSENIYEAFLVG--KPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQG 1000
            F+E++  A  V    P D      + N  S+ E+++K V+ AGLYP + ++R       G
Sbjct: 787  FAEHLLGAGFVSSRNPKD-----PESNINSDNEKIIKAVICAGLYPKVAKIR----LNLG 837

Query: 1001 KFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAV 1060
            K +     Y    G + +H  ++N E T     WL Y + ++++ S+++ D ++V P   
Sbjct: 838  KKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTS-SIYLYDCTEVSPYC- 895

Query: 1061 LLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1116
            LL   GD+ I+ D  + TI++   + +  +  +R   L+KELR+ L  +++  + S
Sbjct: 896  LLFFGGDISIQKDNDQETIAV--DEWIVFQSPARIAHLVKELRKELDILLQEKIES 949


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
          Length = 1369

 Score =  424 bits (1091), Expect = e-118
 Identities = 281/827 (33%), Positives = 441/827 (53%), Gaps = 103/827 (12%)

Query: 390  QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYV-TEGRGARCNVI 448
            +E  QLPV  HRD+I+  +++H VVV++G+TG GK+T++P  LLE  +  E   ++CN++
Sbjct: 567  KERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIV 626

Query: 449  ITQPRRISAVSVAQRVSHELG----PSLRRNV-GFQVRLESKPPSRGGALLFCTVGILLR 503
             TQPRRISAVS+A RV  ELG    P  R ++ G+Q+R+ES+       LL+CT G+LLR
Sbjct: 627  CTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRA-CESTRLLYCTTGVLLR 685

Query: 504  KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRY 563
            KLQ +  L  VSHVIVDEVHER V +DFLLI+LK + +    L L+LMSAT D+E+FS Y
Sbjct: 686  KLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTY 745

Query: 564  FGGCPVIKVPGFMYPVKEHYLEDILAKLG-----KHQYLHRHRHHESE------------ 606
            F  CP++++ G  YPV+  +LEDI+ + G       +Y  +    E E            
Sbjct: 746  FTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGI 805

Query: 607  -----------------------------------DECALDLDLVTDLVLHIDA----RG 627
                                               +   ++LDL+ +L+ ++D     R 
Sbjct: 806  KKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRN 865

Query: 628  EPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRK 687
              G +L FLPG   I+ +   L      +  +Y ++ +HS +   DQ A F  PP GVRK
Sbjct: 866  IEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRK 925

Query: 688  IVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRC 747
            IVLATNIAET ITI D+V V+D+G  KE +Y   +++S L   +VS+A+ +QR+GRAGR 
Sbjct: 926  IVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRV 985

Query: 748  QSGFAYHLFPRSRLEKMVPFQVPEILRTPLENL---VLQAKIHMPEKTAVEFLSKAVDSP 804
            + GF + ++ R R E  + + VPEILR PLE L   +++  +  PE    +FLSKA+D P
Sbjct: 986  RDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPE----DFLSKALDPP 1041

Query: 805  NIKAVDEAVILLQEIGVLDQRE-YLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVV 863
             ++ +  A+ LL++IG  +  E  LT LGQ LA +  + ++ K ++  AIF CL P+  +
Sbjct: 1042 QLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATL 1101

Query: 864  VSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENY 922
             + +T + PF++ +  + E D  K+ L+  + SDHL    A  GW++  +     S   Y
Sbjct: 1102 AAVMTEKSPFTTPIGRKDEADLAKSALAM-ADSDHLTIYNAYLGWKKARQEGGYRSEITY 1160

Query: 923  LEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYS-----EEEELVK 977
               N L   SL  +  + ++  + +  A   G  S  T  S + N  S     +E  L+K
Sbjct: 1161 CRRNFLNRTSLLTLEDVKQELIKLVKAA---GFSSSTTSTSWEGNRASQTLSFQEIALLK 1217

Query: 978  GVLMAGLYPN---LIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRW 1034
             VL+AGLY N   +I  +   VT +      +    T  G   +H S++NR+       W
Sbjct: 1218 AVLVAGLYDNVGKIIYTKSVDVTEK-----LACIVETAQGKAQVHPSSVNRDLQ--THGW 1270

Query: 1035 LTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSR 1094
            L Y   ++    V++R+++ + P  VLL   GD+ ++   R     LS    +  +   +
Sbjct: 1271 LLYQEKIR-YARVYLRETTLITPFPVLLF-GGDIEVQHRER----LLSIDGWIYFQAPVK 1324

Query: 1095 TVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLR 1141
               + K+LR  +  ++ + L +      P +  E+ ++L ++ EL++
Sbjct: 1325 IAVIFKQLRVLIDSVLRKKLEN------PKMSLENDKILQIITELIK 1365


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
          Length = 1270

 Score =  405 bits (1040), Expect = e-112
 Identities = 251/735 (34%), Positives = 388/735 (52%), Gaps = 64/735 (8%)

Query: 388  VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 447
            + QE   LPV      IL AI Q+ VV+I G TGCGKTT++PQ +L+ ++   R A CN+
Sbjct: 381  ILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNI 440

Query: 448  IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 507
            ++TQPRRISAVSVA+RV+ E G    ++ G+ VR ES  P    +++FCTVG+LLRKL++
Sbjct: 441  VVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEA 500

Query: 508  NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 567
               + G+SHVIVDE+HERD+NTDFLL++L+ + +  P +R+VLMSAT D   F  YF  C
Sbjct: 501  G--IRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNC 558

Query: 568  PVIKVPGFMYPVKEHYLEDILA--------KLGKHQYLHRHRHHESEDECAL-------- 611
            P+I+V G  YPV+E++LED +         K  K +        + +  C L        
Sbjct: 559  PIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGP 618

Query: 612  --------------DLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHE 657
                            +L+  L+ +I+    PG +L FLPGW  I  +Q+ L+       
Sbjct: 619  ETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGS 678

Query: 658  SKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEER 717
             +Y ILP+HS IP  +Q+ +F   PVGV K++L+TNIAETSITIND+V+V+DS   K + 
Sbjct: 679  HRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKL 738

Query: 718  YDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPL 777
            +     ++   TVW S+ N+ QR+GRAGR + GF +HL  R+R E++     PE+ RTPL
Sbjct: 739  FTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPL 798

Query: 778  ENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 837
              + L  K+ +      +FL+KA++ P + AV EA   L+E+  LD  + LT LG+ LA 
Sbjct: 799  HEIALSIKL-LRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAK 857

Query: 838  ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSD 896
            +  +PR  K +++  IF     +  + +     +PF   +     +  +    + +  SD
Sbjct: 858  LPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPF---INEGKRLGYIHRNFAGNRFSD 914

Query: 897  HLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKP 956
            H+A +     W++  R     +   + E   L   +LR       Q  E +  +   G P
Sbjct: 915  HVALLSVFQAWDDA-RMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINS---GFP 970

Query: 957  SDCTLASAQCNEYSEEE-ELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGN 1015
             DC L     N   +   ++V  +L  G+YPN+              K       T+  N
Sbjct: 971  EDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCY-----------HKEKRKILTTEGRN 1019

Query: 1016 ILLHKSTIN----REATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLL------TD 1065
             L+HKS++N     +  +  S +  +   +++  ++  +  + V PL +LL       +D
Sbjct: 1020 ALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTR-AISAKGMTLVTPLQLLLFASKKVQSD 1078

Query: 1066 GDVHIRDDGRRATIS 1080
            G + + DD  +  IS
Sbjct: 1079 GQIVLVDDWIKLQIS 1093


>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
           sapiens]
          Length = 1143

 Score =  311 bits (796), Expect = 3e-84
 Identities = 204/572 (35%), Positives = 308/572 (53%), Gaps = 43/572 (7%)

Query: 384 RRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGA 443
           R   + +E   LP+  + + IL  +++H VVV++GDTGCGK+T++PQ LL    +     
Sbjct: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFS----- 205

Query: 444 RCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLR 503
             +V  TQPRRI+ +S+A+RV  E        VG+Q+R ES   S    ++F TVG+LLR
Sbjct: 206 --HVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTR-SAATKIVFLTVGLLLR 262

Query: 504 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRY 563
           ++Q  PSL     +IVDEVHER ++ DFLL +L+ L    P L+++LMSAT +   FS Y
Sbjct: 263 QIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSY 322

Query: 564 FGGCPVIKVPGFMYPVKEHY----LEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDL 619
           F   PV++VPG ++P+   Y     E   +K  K       R  ES D            
Sbjct: 323 FSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESID------------ 370

Query: 620 VLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQ 679
             H     E G +L FL G  EI  V +  Q     H  ++++LP+HS + + DQ  +F 
Sbjct: 371 --HKYPPEERGDLLVFLSGMAEISAVLEAAQ-TYASHTQRWVVLPLHSALSVADQDKVFD 427

Query: 680 QPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQ 739
             P GVRK +L+TNIAETS+TI+ I  VVDSG  KE  YD + K+  L+  W+S+A+  Q
Sbjct: 428 VAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQ 487

Query: 740 RRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLS 798
           R+GRAGR   G  + L+  S  +   P+ VPEI R  L++LVLQ K + + +     F  
Sbjct: 488 RKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPF-- 545

Query: 799 KAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLH 858
             ++ P   +++ A++ L++ G LD  E LT +G  LA +  D  + K ++L ++F  + 
Sbjct: 546 --IEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVE 603

Query: 859 PLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRS 917
           P+L + + L+ + PF+ S Q+  E    +  L  D G D          W +V   + R+
Sbjct: 604 PVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQG-DPFTLFNVFNAWVQVKSERSRN 662

Query: 918 SRE----NYLEENLLYAPSLRFIHGLIKQFSE 945
           SR+      +EE+ LY      +  L +QF E
Sbjct: 663 SRKWCRRRGIEEHRLYE-----MANLRRQFKE 689


>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
          Length = 1041

 Score =  280 bits (715), Expect = 7e-75
 Identities = 213/656 (32%), Positives = 322/656 (49%), Gaps = 61/656 (9%)

Query: 395  LPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGRGARCNVIITQPR 453
            LPV P R+ +L AI  H V++I G+TG GKTT+IPQ L E  Y  +G    C    TQPR
Sbjct: 399  LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC----TQPR 454

Query: 454  RISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEG 513
            R++A+SVA RV+ E+G  L   VG+ +R E     R   L + T G+LLR+  S P L  
Sbjct: 455  RVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERT-VLRYMTDGMLLREFLSEPDLAS 513

Query: 514  VSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVP 573
             S V+VDE HER ++TD L  L+K + R  P L++++ SAT D  RFS +F   PV ++P
Sbjct: 514  YSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIP 573

Query: 574  GFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGIL 633
            G  +PV   Y      K  +  YL         + C +        VL I     PG IL
Sbjct: 574  GRRFPVDIFY-----TKAPEADYL---------EACVVS-------VLQIHVTQPPGDIL 612

Query: 634  CFLPGWQEIKGVQQRLQEA---LGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVL 690
             FL G +EI+   + LQ+    LG    + L+LP+++N+P   Q  IFQ  P G RK+V+
Sbjct: 613  VFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVV 672

Query: 691  ATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSG 750
            ATNIAETS TI  I++V+D G  K++ Y+ +T +  L     S+A+  QR GRAGR  +G
Sbjct: 673  ATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAG 732

Query: 751  FAYHLFPR-SRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLSKAVDSPNIKA 808
              + L+   +   ++    VPEI RT L N+VL  K + + +    +FL    D P  + 
Sbjct: 733  KCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFL----DPPPYET 788

Query: 809  VDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT 868
            +   +  L  +G L+    LTT G+++A +  DP L+K I+ +  + C   +L V + L+
Sbjct: 789  LLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLS 848

Query: 869  RDPFSSSLQNRAEVDKVKALLSHDS----GSDHLAFVRAVAGWEEVLRWQDRSSRENYLE 924
                ++S+  R +   V A  +  +    G DHL  +          +W +      +  
Sbjct: 849  ---VNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYT------QWAESGYSSQWCC 899

Query: 925  ENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGL 984
            EN +   S+R    + +Q  E + E   VG      L+S Q +     + +  G      
Sbjct: 900  ENFVQFRSMRRARDVREQL-EGLLERVEVG------LSSCQGDYIRVRKAITAGYFYHTA 952

Query: 985  YPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTIN-----REATRLRSRWL 1035
                   R  K  +     PNS  +  +   +L H+  +      R+   + S WL
Sbjct: 953  RLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWL 1008


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score =  270 bits (691), Expect = 4e-72
 Identities = 204/668 (30%), Positives = 334/668 (50%), Gaps = 66/668 (9%)

Query: 388  VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 447
            + ++   LP+   ++ ++ A+  + ++++ G+TG GKTT+I Q L E     G  +R  +
Sbjct: 558  ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEA----GYTSRGKI 613

Query: 448  IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 507
              TQPRR++A+SVA+RVS E G  L + VG+ +R E    S    + + T G+LLR+   
Sbjct: 614  GCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCT-SPETVIKYMTDGMLLRECLI 672

Query: 508  NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 567
            +P L   + +++DE HER ++TD L  LLK   +    ++L++ SAT D  +FS+YF   
Sbjct: 673  DPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEA 732

Query: 568  PVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARG 627
            P+  +PG  YPV+  Y ++                    +   LD  L+T + +H+    
Sbjct: 733  PIFTIPGRTYPVEILYTKE-------------------PETDYLDASLITVMQIHLTE-- 771

Query: 628  EPGGILCFLPGWQEIKGVQQRLQE---ALGMHESKYLILPVHSNIPMMDQKAIFQQPPVG 684
             PG IL FL G +EI    + L E   +LG    + +ILPV+S +P   Q  IF   P G
Sbjct: 772  PPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPG 831

Query: 685  VRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRA 744
             RK+V+ATNIAETS+TI+ I +VVD G  K++ Y+ KT +  L    +S+A   QR GRA
Sbjct: 832  SRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRA 891

Query: 745  GRCQSGFAYHLF-PRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLSKAVD 802
            GR   G  Y L+  R+  ++M+   VPEI RT L + VL  K + + +  + +F+    D
Sbjct: 892  GRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFM----D 947

Query: 803  SPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLV 862
            +P ++ +  A+  L  +G LD    LT LG+R+A    +P L K ++++    C   +L 
Sbjct: 948  APPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLT 1007

Query: 863  VVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN 921
            +VS L+ ++ F      +A  D+ KA   H +  DHL  +           W++      
Sbjct: 1008 IVSMLSVQNVFYRPKDKQALADQKKAKF-HQTEGDHLTLLAVYNS------WKNNKFSNP 1060

Query: 922  YLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLM 981
            +  EN + A SLR    + KQ         ++G      L    C + +     V+  + 
Sbjct: 1061 WCYENFIQARSLRRAQDIRKQ---------MLGIMDRHKLDVVSCGKSTVR---VQKAIC 1108

Query: 982  AGLYPNLIQ--VRQGKVTRQGK----FKPNSVTYRTKSGNILLHKSTIN-----REATRL 1030
            +G + N  +   ++G  T   +      P+S  +  +   ++ H+  +      RE T +
Sbjct: 1109 SGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTI 1168

Query: 1031 RSRWLTYF 1038
              RWL  F
Sbjct: 1169 DPRWLVEF 1176


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score =  267 bits (683), Expect = 4e-71
 Identities = 182/562 (32%), Positives = 296/562 (52%), Gaps = 65/562 (11%)

Query: 393 PQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQP 452
           P LP+  +++ +++ IE + VV+I G TG GK+T++PQ +L+ YV   R A C++++TQP
Sbjct: 130 PDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQ--RSAYCSIVVTQP 187

Query: 453 RRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLE 512
           R+I A S+A+ +S E   +L   VG+QV LE K  +    L++ T G+LL+K+ S  SL 
Sbjct: 188 RKIGASSIARWISKERAWTLGGVVGYQVGLE-KIATEDTRLIYMTTGVLLQKIVSAKSLM 246

Query: 513 GVSHVIVDEVHERDVNTDFLLILLKGLQRLNPA-LRLVLMSATGDNERFSRYFG------ 565
             +H+I+DEVHER    DFLL++++ L R N   +++VLMSAT   + F+ YF       
Sbjct: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306

Query: 566 --GCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHI 623
                + +V G  + V+E+YL D+            H HH       L+  ++T  +  +
Sbjct: 307 MNPAYIFEVEGKPHSVEEYYLNDL-----------EHIHHSKLSPHLLEEPVITKDIYEV 355

Query: 624 -----------DARG-------------EPGGILCFLPGWQEIKGVQQRLQEALGMHESK 659
                      D +              E   +L FLPG  EI  + + L   +     +
Sbjct: 356 AVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLV---HKR 412

Query: 660 YLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYD 719
             + P+HS++ + +Q  +F  P  G RKI+L+TNIAE+S+T+ D+ +V+D  L +    D
Sbjct: 413 LQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCD 472

Query: 720 LKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVP-FQVPEILRTPLE 778
             T    L   W S+ +  QR+GRAGR   G+ Y L  +   +  +P   VPE+LR PL 
Sbjct: 473 EDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLG 532

Query: 779 NLVLQAK-IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVL---DQRE-------Y 827
           + +L+ K + M E  A+  L+ A+  P +  ++  ++LL+E+G L    QRE        
Sbjct: 533 STILKVKLLDMGEPRAL--LATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGE 590

Query: 828 LTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVK 886
           LT LG+ LA +  + +L K IVL  +F CL   L++ + L+ ++ F+   +   +  + K
Sbjct: 591 LTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNK 650

Query: 887 ALLSHDSGSDHLAFVRAVAGWE 908
              S  S SD +A V A   W+
Sbjct: 651 VNFSGSSKSDCIALVEAFKTWK 672


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score =  261 bits (668), Expect = 2e-69
 Identities = 169/507 (33%), Positives = 267/507 (52%), Gaps = 35/507 (6%)

Query: 602  HHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRL---QEALGMHES 658
            HH  +DE  +DLDL+  L+ +I    + G +L FLPG+ EI G++ R+    +    +  
Sbjct: 596  HHSFDDE-KVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTH 654

Query: 659  KYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERY 718
            +Y +  +HSN+   DQK + + PP GVRKI+L+TNIAETSIT+ND+V V+DSG  KE+ +
Sbjct: 655  RYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSF 714

Query: 719  DLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLE 778
            D    V+ L+ VW+S+A+ IQR+GRAGRC+ G  + LF R R + M+ FQ PE+LR PL+
Sbjct: 715  DALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQ 774

Query: 779  NLVLQAKIHMPEKTAV-EFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAH 837
             L L  K+  P    + +FL KA + P    V  AV +L+ I  +D  E LT LG  LA 
Sbjct: 775  ELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLAD 834

Query: 838  ISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPF---SSSLQNRAEVDKVKALLSHDS 893
            +  +P L K ++ A + +CL P+L +   L  RDPF   + + Q RA +   +   +  +
Sbjct: 835  LPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAM-LCRKRFTAGA 893

Query: 894  GSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLV 953
             SDH+A +RA   W++    +       + E+N L   ++  I G+  Q    +  +  V
Sbjct: 894  FSDHMALLRAFQAWQKA---RSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFV 950

Query: 954  GKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQ------GKVTRQGKFKPNSV 1007
                   +     N  SE   +VK  L+AG+YPNL+ V +      G   ++ +F P SV
Sbjct: 951  RARGGGDIRDVNTN--SENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASV 1008

Query: 1008 TYRTKSGNILLHKSTINREATRLR---SRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLT 1064
              + +   I       N +A  ++   + WL Y    +++    +R  S V P+ +L+  
Sbjct: 1009 LSQPQYKKI----PPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFC 1064

Query: 1065 DGDVHIRDDGRRATISLSDSDLLRLEG 1091
                      R A+ +L +    R++G
Sbjct: 1065 -------GPARLASNALQEPSSFRVDG 1084



 Score =  168 bits (425), Expect = 3e-41
 Identities = 117/345 (33%), Positives = 190/345 (55%), Gaps = 32/345 (9%)

Query: 274 KSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPV---ES 330
           +SLGLV ++     +  Y     ++  ET     T  +       + + +  +PV   E 
Sbjct: 83  QSLGLVSKSKGKGANR-YLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKER 141

Query: 331 SWIAPELRLQS-----DDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRR 385
           + + P+    +      +   + K SG L++   G P +P      V+  +S  + +R+ 
Sbjct: 142 TELLPKTERGNVFAVEAENREMSKTSGRLNN---GIPQIP------VKRGESEFDSFRQS 192

Query: 386 GPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARC 445
            PV+++         ++ I+  I+++ VV+I G+TG GKTT+IPQ LL+     G    C
Sbjct: 193 LPVFEK---------QEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNG--IPC 241

Query: 446 NVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKL 505
            +  TQPRR++A++VA+RV+ E    + + +G+Q+RLES+   +   L FCT G+LLR L
Sbjct: 242 RIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKT-LLTFCTNGVLLRTL 300

Query: 506 QSNPS-LEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYF 564
            +  S L  V+HVIVDEVHERD  +DFLL  L+ L + +P L+L+L SA  D   F RYF
Sbjct: 301 MAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYF 360

Query: 565 GGCPVIKVPGFMYPVKEHYLEDILAKLG-KHQYLHRHRHHESEDE 608
           G CPVI + G  + VKE +LEDIL   G  ++ + +++  + ++E
Sbjct: 361 GSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEE 405


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
            sapiens]
          Length = 1386

 Score =  256 bits (653), Expect = 1e-67
 Identities = 169/518 (32%), Positives = 278/518 (53%), Gaps = 33/518 (6%)

Query: 629  PGGILCFLPGWQEIKGVQQRLQEAL---GMHESKYLILPVHSNIPMMDQKAIFQQPPVGV 685
            PG IL FLPG  EIK + ++LQ          ++ +I P+HS++   +Q+A+F +PP GV
Sbjct: 847  PGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGV 906

Query: 686  RKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAG 745
             KI+++TNIAETSITI+D+V+V+DSG  KE+RYD    +  LE  +VS+AN +QR+GRAG
Sbjct: 907  TKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAG 966

Query: 746  RCQSGFAYHLFPRSRL-EKMVPFQVPEILRTPLENLVLQAKI--HMPEKTAVEFLSKAVD 802
            R  SG  +HLF       +++  Q+PEI R PLE L L+ KI             S+ ++
Sbjct: 967  RVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIE 1026

Query: 803  SPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLV 862
             P+  ++  + I L+++G L   E LT LG  LA +  D R+ K ++  +IFRCL P L 
Sbjct: 1027 PPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALT 1086

Query: 863  VVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN 921
            + + L  + PF S    + E ++ K   +  + SD+LA ++A  GW+   +   R+S  N
Sbjct: 1087 IAASLAFKSPFVSPWDKKEEANQKKLEFAF-ANSDYLALLQAYKGWQLSTKEGVRAS-YN 1144

Query: 922  YLEENLLYAPSLRFIHGLIKQFSENI--------------YEAFLVGKPSDCTLASAQCN 967
            Y  +N L    L+ +  L +QF+E +               E    G          + N
Sbjct: 1145 YCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEAN 1204

Query: 968  EYSEEEELVKGVLMAGLYPNLIQVR--QGKVTRQG----KFKPNS--VTYRTKS-GNILL 1018
              +E  +L+  +L A LYPN++QV+  +GK  +      + +P S  + + TK+ G + +
Sbjct: 1205 SNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHI 1264

Query: 1019 HKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRAT 1078
            H S++N +     S +L Y   +K++  VF+RD S V    ++L   G V+++       
Sbjct: 1265 HPSSVNYQVRHFDSPYLLYHEKIKTS-RVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFV 1323

Query: 1079 ISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1116
            +SL D  +  +    +   L+KELR  L ++++  +++
Sbjct: 1324 VSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKN 1361



 Score =  199 bits (506), Expect = 1e-50
 Identities = 103/202 (50%), Positives = 139/202 (68%), Gaps = 1/202 (0%)

Query: 388 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 447
           + QE   LP    R+TILN + +H VVVISG TGCGKTT+IPQ +L+  +        N+
Sbjct: 537 ILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANI 596

Query: 448 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 507
           I TQPRRISA+SVA+RV+ E    +   VG+Q+RLES   S    LL+CT G+LLR+L+ 
Sbjct: 597 ICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSS-ATRLLYCTTGVLLRRLEG 655

Query: 508 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 567
           + +L+GVSH+IVDEVHER   +DFLL++LK +    P L+++LMSAT + E FS YF  C
Sbjct: 656 DTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSC 715

Query: 568 PVIKVPGFMYPVKEHYLEDILA 589
           PVI +PG  +PV + +LED +A
Sbjct: 716 PVITIPGRTFPVDQFFLEDAIA 737


>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
           sapiens]
          Length = 795

 Score =  251 bits (641), Expect = 3e-66
 Identities = 170/529 (32%), Positives = 284/529 (53%), Gaps = 41/529 (7%)

Query: 394 QLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPR 453
           QLPV  ++D   + + +H   V+ G+TG GKTT+IPQ  +E Y+    G +  V  TQPR
Sbjct: 136 QLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVE-YMRSLPGPKRGVACTQPR 194

Query: 454 RISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEG 513
           R++A+SVAQRV+ E+   L + VG+ +R E    ++   L + T G+LLR+  ++P LE 
Sbjct: 195 RVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKT-ILKYMTDGMLLREAMNDPLLER 253

Query: 514 VSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVP 573
              +I+DE HER + TD L+ +LK + R    L++++MSAT D  +F  YF  CP++ +P
Sbjct: 254 YGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIP 313

Query: 574 GFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGIL 633
           G  +PV+  Y  +                    +   L+  + T + +H+    E G +L
Sbjct: 314 GRTHPVEIFYTPE-------------------PERDYLEAAIRTVIQIHM-CEEEEGDLL 353

Query: 634 CFLPGWQEIKGVQQRLQ---EALGMHESKYLILPVHSNIPMMDQKAIFQQPP-------V 683
            FL G +EI    +R++   + LG       I+P++S +P   Q+ IF+ PP       +
Sbjct: 354 LFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAI 413

Query: 684 GVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGR 743
           G RK+V++TNIAETS+TI+ +V V+D G  K++ Y+ + +V  L    +S+A+  QR GR
Sbjct: 414 G-RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGR 472

Query: 744 AGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAVEFLSKAV 801
           AGR + G  + L+     + +M     PEILR+ L ++VLQ  K+ + +    +F+    
Sbjct: 473 AGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFM---- 528

Query: 802 DSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLL 861
           D P  + +  A+ LL  +  L+    LT LG  +A    DP+LAK ++ +  + C + +L
Sbjct: 529 DPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 588

Query: 862 VVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEE 909
            + + L+    F    + +   D+ K   +H  G DHL  +     +++
Sbjct: 589 SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDG-DHLTLLNVYHAFKQ 636


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
          Length = 1227

 Score =  251 bits (640), Expect = 4e-66
 Identities = 177/577 (30%), Positives = 305/577 (52%), Gaps = 41/577 (7%)

Query: 373  RLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLL 432
            R S++  E  +++  + ++   LP+   +  +L  I  + +V++ G+TG GKTT++ Q L
Sbjct: 511  RKSEASSEFAKKKS-ILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYL 569

Query: 433  LERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGA 492
             E   T+     C    TQPRR++A+SVA+RVS E+G +L   VG+ +R E    S    
Sbjct: 570  HEDGYTDYGMIGC----TQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCT-SENTL 624

Query: 493  LLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMS 552
            + + T GILLR+      L+  S +I+DE HER +NTD L  LL+ +      L+L++ S
Sbjct: 625  IKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLIVTS 684

Query: 553  ATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALD 612
            AT D E+F+ +FG  P+  +PG  +PV      DIL               ++  E  ++
Sbjct: 685  ATMDAEKFAAFFGNVPIFHIPGRTFPV------DILFS-------------KTPQEDYVE 725

Query: 613  LDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK--YLILPVHSNIP 670
              +   L +H+   G PG IL F+PG ++I+    ++ E L   E+     +LP++S +P
Sbjct: 726  AAVKQSLQVHLS--GAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLP 783

Query: 671  MMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETV 730
               Q  IFQ+ P GVRK ++ATNIAETS+T++ I+ V+DSG  K + ++ +  +  L+  
Sbjct: 784  SDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIY 843

Query: 731  WVSRANVIQRRGRAGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQAKIHMP 789
             +S+AN  QR GRAGR   G  + L+ +S  + +++   VPEI RT L N+VL  K  + 
Sbjct: 844  PISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK-SLG 902

Query: 790  EKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIV 849
             +  ++F    +D P    +  ++  L  +G LD    LT+ G+ +     DP L+K ++
Sbjct: 903  VQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI 960

Query: 850  LAAIFRCLHPLLVVVSCLTRDP-FSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWE 908
            ++    C   +L++VS L+    F        E D+++   +    SDHL ++       
Sbjct: 961  VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPE-SDHLTYLNV----- 1014

Query: 909  EVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSE 945
              L+W++ +    +  ++ ++A ++R +  +  Q  +
Sbjct: 1015 -YLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKD 1050


>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
           sapiens]
          Length = 707

 Score =  246 bits (627), Expect = 1e-64
 Identities = 179/538 (33%), Positives = 281/538 (52%), Gaps = 56/538 (10%)

Query: 379 LELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVT 438
           +EL RR  P++Q   QL         L  +      V+ G+TG GKTT+IPQ     Y+ 
Sbjct: 67  VELQRRSLPIFQARGQL---------LAQLRNLDNAVLIGETGSGKTTQIPQ-----YLY 112

Query: 439 EGRGARCNVI-ITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCT 497
           EG  +R  +I +TQPRR++A+S+A RVS E    L + VG+ VR +    S    + F T
Sbjct: 113 EGGISRQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVT-SEDTRIKFLT 171

Query: 498 VGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPAL-----RLVLMS 552
            G+LLR+  S+  L   S VI+DE HER ++TD L  ++K  Q+    L     ++++MS
Sbjct: 172 DGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMS 231

Query: 553 ATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALD 612
           AT D + FS+YF G PV+ + G  +P++  Y      K  ++ YLH              
Sbjct: 232 ATMDVDLFSQYFNGAPVLYLEGRQHPIQVFY-----TKQPQNDYLHAA------------ 274

Query: 613 LDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK----YLILPVHSN 668
             LV+   +H +A      IL FL G +EI+ + +  ++ +  H        L+LP++++
Sbjct: 275 --LVSVFQIHQEAPSSQD-ILVFLTGQEEIEAMSKTCRD-IAKHLPDGCPAMLVLPLYAS 330

Query: 669 IPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLE 728
           +P   Q  +FQ  P G RK++++TNIAETSITI  I +VVD+G+ K ++Y+  + +  L 
Sbjct: 331 LPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLA 390

Query: 729 TVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQ-AKIH 787
              VS+    QR GRAGR  SG  Y L+     EK     VPEI R  L +++LQ   + 
Sbjct: 391 VQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMK 450

Query: 788 MPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQRE---YLTTLGQRLAHISTDPRL 844
           +P     +F+SK    P+   +  A+  L  +G L+ ++    LT +G+++A    +P+ 
Sbjct: 451 VPNVLTFDFMSK----PSPDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKF 506

Query: 845 AKAIVLAAIFRCLHPLLVVVSCLTRDP-FSSSLQNRAEVDKVKALLSHDSGSDHLAFV 901
           AK I+++  F C   +L +VS L+ D    +    R EV  V+       G DH+  +
Sbjct: 507 AKTILMSPKFHCTEEILTIVSLLSVDSVLHNPPSRREEVQGVRKKFISSEG-DHMTLL 563


>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
           sapiens]
          Length = 703

 Score =  241 bits (614), Expect = 4e-63
 Identities = 166/497 (33%), Positives = 262/497 (52%), Gaps = 49/497 (9%)

Query: 390 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGRGARCNVI 448
           Q+  +LPV   R+ IL  IE +  VVI G+TGCGK+T+IPQ L E  +  EGR     V 
Sbjct: 49  QQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRV----VG 104

Query: 449 ITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSN 508
           +TQPRR++AV+VA RV+ E G  L   VG+ +R +         + F T G+L+R++  +
Sbjct: 105 VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVD 164

Query: 509 PSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGG-- 566
           P L   S +++DE HER + TD  + LLK +Q+    LRL++ SAT D ++F  +F    
Sbjct: 165 PLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNE 224

Query: 567 --------CPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTD 618
                   C ++ V G  +PV   YL+  +    K       + H++E +          
Sbjct: 225 TSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGD---------- 274

Query: 619 LVLHIDARGEPGGILCFLPGWQEIKGV------QQRLQEALGMHESKYLILPVHSNIPMM 672
                      G +L FL G +E++ V      Q R     GM +    +LP+++ +P  
Sbjct: 275 -----------GDVLAFLTGQEEVETVVSMLIEQARALARTGM-KRHLRVLPMYAGLPSF 322

Query: 673 DQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWV 732
           +Q  +F++    VRK+++ATN+AETSITI+ IV+V+D G  K   Y+ +T + CL  V V
Sbjct: 323 EQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPV 382

Query: 733 SRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEK 791
           S+A+  QR GR GR +SG  Y L+     +K+    VPE+ R+ L  ++LQ K + +   
Sbjct: 383 SQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNV 442

Query: 792 TAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLT-TLGQRLAHISTDPRLAKAIVL 850
               F+S     P  +++ +A+ LL  +G LD+   LT  LG R+A    +P  AK ++ 
Sbjct: 443 LRFHFMS----PPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLE 498

Query: 851 AAIFRCLHPLLVVVSCL 867
           +  F C   +L + + +
Sbjct: 499 SGNFGCSQEILSIAAMM 515


>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
           sapiens]
          Length = 779

 Score =  238 bits (608), Expect = 2e-62
 Identities = 169/538 (31%), Positives = 275/538 (51%), Gaps = 47/538 (8%)

Query: 368 EAEEVRLSQSLLELWRRRGPVWQEA---PQLPVDPHRDTILNAIEQHPVVVISGDTGCGK 424
           + +E RLS   +     +G   QE    P  P+   R  I+ A+  +  ++++G+TG GK
Sbjct: 23  DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82

Query: 425 TTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLES 484
           TT++P+ L E     G      + +TQPR+++A+SVAQRV+ E+  +L   VG+QVR + 
Sbjct: 83  TTQLPKYLYEA----GFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138

Query: 485 KPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL-QRLN 543
              S+  A+ + T G LL+ +  +P+L   S +I+DE HER + TD L  LLK L Q  +
Sbjct: 139 CS-SKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKS 197

Query: 544 PA----LRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHR 599
           P     L++V+MSAT +  + S +FG CP+  +PG +YPV+E +   I  +         
Sbjct: 198 PNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPR--------- 248

Query: 600 HRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK 659
                 + E    +  + ++ + I      G IL FL G  EI+   + L +     +  
Sbjct: 249 ------DRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302

Query: 660 Y----------LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVD 709
           Y          LILP + ++    Q+ IF  PP G+RK V++TNI+ TS+TI+ I +VVD
Sbjct: 303 YDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362

Query: 710 SGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQV 769
            G  K+  ++ +  +  LE V +S++  +QR GRAGR  SG  + ++ +    + +P  V
Sbjct: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422

Query: 770 -PEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYL 828
            PEI RT L ++VL  K  +     + F    +D PN + + EA+  L +   +D+  ++
Sbjct: 423 IPEIKRTSLTSVVLTLKC-LAIHDVIRF--PYLDPPNERLILEALKQLYQCDAIDRSGHV 479

Query: 829 TTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRD-----PFSSSLQNRAE 881
           T LG  +      P L  A++ AA   C   LL + + L+ +     P     Q  AE
Sbjct: 480 TRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAE 537


>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
           polypeptide 40 [Homo sapiens]
          Length = 452

 Score =  216 bits (549), Expect = 1e-55
 Identities = 145/437 (33%), Positives = 232/437 (53%), Gaps = 39/437 (8%)

Query: 368 EAEEVRLSQSLLELWRRRGPVWQEA---PQLPVDPHRDTILNAIEQHPVVVISGDTGCGK 424
           + +E RLS   +     +G   QE    P  P+   R  I+ A+  +  ++++G+TG GK
Sbjct: 23  DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGK 82

Query: 425 TTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLES 484
           TT++P+ L E     G      + +TQPR+++A+SVAQRV+ E+  +L   VG+QVR + 
Sbjct: 83  TTQLPKYLYEA----GFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138

Query: 485 KPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGL-QRLN 543
              S+  A+ + T G LL+ +  +P+L   S +I+DE HER + TD L  LLK L Q  +
Sbjct: 139 CS-SKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKS 197

Query: 544 PA----LRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHR 599
           P     L++V+MSAT +  + S +FG CP+  +PG +YPV+E +   I  +         
Sbjct: 198 PNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPR--------- 248

Query: 600 HRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESK 659
                 + E    +  +  + + I      G IL FL G  EI+   + L +     +  
Sbjct: 249 ------DRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYD 302

Query: 660 Y----------LILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVD 709
           Y          LILP + ++    Q+ IF  PP G+RK V++TNI+ TS+TI+ I +VVD
Sbjct: 303 YDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVD 362

Query: 710 SGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQV 769
            G  K+  ++ +  +  LE V +S++  +QR GRAGR  SG  + ++ +    + +P  V
Sbjct: 363 GGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHV 422

Query: 770 -PEILRTPLENLVLQAK 785
            PEI RT L ++VL  K
Sbjct: 423 IPEIKRTSLTSVVLTLK 439


>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
           sapiens]
          Length = 743

 Score =  149 bits (376), Expect = 2e-35
 Identities = 123/501 (24%), Positives = 240/501 (47%), Gaps = 39/501 (7%)

Query: 390 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVII 449
           +E   LP+   + + +  + Q+ +V++SGD  CGK+ ++PQ   E Y          VI 
Sbjct: 57  KEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAE-YCLSIHYQHGGVIC 115

Query: 450 TQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNP 509
           TQ  + + V +A RV+ E+  ++   VG+ +  E+   +    L +CT  +L R++ SNP
Sbjct: 116 TQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNET-ILRYCTDDMLQREMMSNP 174

Query: 510 SLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPV 569
            L     +I+D++HER + TD LL LLK +    P L+L++ S+     + + Y+G  PV
Sbjct: 175 FLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPV 234

Query: 570 IKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEP 629
           I+V    +PV+  YL                   E++ +     + +  L+  I   GE 
Sbjct: 235 IEVKN-KHPVEVVYLS------------------EAQKD---SFESILRLIFEIHHSGEK 272

Query: 630 GGILCFLPGWQEIKGVQQRLQEALGMHE--SKYLILPVH-----SNIPMMDQKAIFQQPP 682
           G I+ FL   Q+I+ V + + +   ++    + +++P++     S    +D+    ++  
Sbjct: 273 GDIVVFLACEQDIEKVCETVYQGSNLNPDLGELVVVPLYPKEKCSLFKPLDETE--KRCQ 330

Query: 683 VGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRG 742
           V  R++VL T+  E  I  N +  V+D G+ + + Y+ + + + L    +S++    R+ 
Sbjct: 331 VYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQ 390

Query: 743 RAGRCQSGFAYHLFPRSRLEK-MVPFQVPEILRTPLENLVL-QAKIHMPEKTAVEFLSKA 800
             G   SG  + L+      K M P +  E+    L ++VL   +I +      +F+++ 
Sbjct: 391 ILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRP 450

Query: 801 VDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPL 860
                ++A+++    L  +  LD    L+  G  ++    DP+L+K+I+ +  F C+  +
Sbjct: 451 APESLMQALED----LDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEV 506

Query: 861 LVVVSCLTRDPFSSSLQNRAE 881
           L + + +T     S + + AE
Sbjct: 507 LTIAAMVTAPNCFSHVPHGAE 527


>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
           sapiens]
          Length = 717

 Score =  141 bits (355), Expect = 4e-33
 Identities = 141/517 (27%), Positives = 234/517 (45%), Gaps = 39/517 (7%)

Query: 395 LPVDPHRDTILNAIEQHP--VVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQP 452
           LP+   R T L  +E +P  VV++SG+ G GK+T+IPQ   E  +  G   +  V +TQP
Sbjct: 45  LPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGF-QKGQVTVTQP 103

Query: 453 RRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLE 512
             ++A S+A RV+ E+  +L   VG+ +  E         L FC   +LL+++ S     
Sbjct: 104 YPLAARSLALRVADEMDLTLGHEVGYSIPQEDCT-GPNTLLRFCWDRLLLQEVASTRGTG 162

Query: 513 GVSHVIVDEVHERDVNTDFLLILLKG--LQRLNPALRLVLMSATGDNERFSRYFGGCPVI 570
               +++DE  ER V +D L  LL+   L++L   LR+V+++      +   ++G  P++
Sbjct: 163 AWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWGNPPIV 222

Query: 571 KVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPG 630
            +P            D +                 E  C          VL +  +  PG
Sbjct: 223 HIPREPGERPSPIYWDTIPP------------DRVEAAC--------QAVLELCRKELPG 262

Query: 631 GILCFLPGWQEIKGVQQRLQ---EALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRK 687
            +L FLP  +EI    + L    E+L +      +LP+H +     Q A+++   +  RK
Sbjct: 263 DVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQ-AVYED--MDARK 319

Query: 688 IVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRC 747
           +V+   +A+ S ++  I HV+DSGL     Y+ + +        +S+     RR RA   
Sbjct: 320 VVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGF 379

Query: 748 QSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQAKIH-MPEKTAVEFLSKAVDSPN 805
             G    L+P+S LE +  P   P +    L +LVL  K   + E     FL    D P 
Sbjct: 380 PPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFL----DQPA 435

Query: 806 IKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVS 865
            +A+ +A+  L  +  LD    L+ LG  L+     P LAKA++ +  F C+  +L + +
Sbjct: 436 PEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAA 495

Query: 866 CLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVR 902
            LT  P  +     AE   ++  L H  G DH + ++
Sbjct: 496 MLTAAPGFTRPPLSAEEAALRRALEHTDG-DHSSLIQ 531


>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
           sapiens]
          Length = 1157

 Score =  124 bits (310), Expect = 7e-28
 Identities = 104/323 (32%), Positives = 161/323 (49%), Gaps = 40/323 (12%)

Query: 344 ILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLE----LWRRRGPVWQEAP-QLPVD 398
           + PL     P S P+     VP   A    L ++L +    +   R P  QE   +LP+ 
Sbjct: 196 VAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPIL 255

Query: 399 PHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVI-ITQPRRISA 457
                I+ A+ +HP+V++ G+TG GKTT++PQ L E     G  +  ++I +T+PRR++A
Sbjct: 256 SEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYE----AGFSSEDSIIGVTEPRRVAA 311

Query: 458 VSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHV 517
           V+++QRV+ E+  S +R V +Q+R E    +    + F T G+LL+++Q +  L     V
Sbjct: 312 VAMSQRVAKEMNLS-QRVVSYQIRYEGN-VTEETRIKFMTDGVLLKEIQKDFLLLRYKVV 369

Query: 518 IVDEVHERDVNTDFLLILLKGLQRL----NPALRLVLMSATGDNERFSR----YFGGCPV 569
           I+DE HER V TD L+ LL  +  L    N  L+L++MSAT   E F++    +    PV
Sbjct: 370 IIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPV 429

Query: 570 IKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEP 629
           IKV    +PV  H+ +             R    +   EC          V  I      
Sbjct: 430 IKVESRQFPVTVHFNK-------------RTPLEDYSGECFRK-------VCKIHRMLPA 469

Query: 630 GGILCFLPGWQEIKGVQQRLQEA 652
           GGIL FL G  E+  + +RL++A
Sbjct: 470 GGILVFLTGQAEVHALCRRLRKA 492



 Score =  121 bits (303), Expect = 4e-27
 Identities = 95/294 (32%), Positives = 137/294 (46%), Gaps = 42/294 (14%)

Query: 606 EDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPV 665
           E+E ALD DL  DL       G+ GG               ++   +L +H     +LP+
Sbjct: 558 EEEGALDSDLDLDL----GDGGQDGG---------------EQPDASLPLH-----VLPL 593

Query: 666 HSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVS 725
           +S +    Q  +F+ PP G R  V+ATN+AETS+TI  I +VVD G  K+  YD  T VS
Sbjct: 594 YSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVS 653

Query: 726 CLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK 785
                WVS+A+  QR GRAGR + G  Y L+  +       F  PEI R P+E+L+LQ K
Sbjct: 654 SFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMK 713

Query: 786 IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREY---------------LTT 830
               EK  + F       P+++A+  A  LL  +G L   +                +T 
Sbjct: 714 ALNVEK-VINF--PFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITA 770

Query: 831 LGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDK 884
           LG+ +A     PR AK + L+    CL   + +V+ +T       L   A  D+
Sbjct: 771 LGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDE 824


>gi|4885615 signal transducer and activator of transcription 2 [Homo
           sapiens]
          Length = 851

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 14/134 (10%)

Query: 267 ALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHY 326
           A  C   + + L +R    L H +  + S R++ E Q+ P  ++ PEP L  +E  L   
Sbjct: 673 AFGCYYQEKVNLQERRKY-LKHRLI-VVSNRQVDELQQ-PLELK-PEPELESLELELGLV 728

Query: 327 PVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRRG 386
           P       PEL L  + +L  G D GP  + +      P++E     +SQ++ E    +G
Sbjct: 729 P------EPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPE--PDQG 780

Query: 387 PVWQEAPQ--LPVD 398
           PV Q  P+  LP D
Sbjct: 781 PVSQPVPEPDLPCD 794


>gi|4758532 ral guanine nucleotide dissociation stimulator-like 2
           [Homo sapiens]
          Length = 777

 Score = 37.4 bits (85), Expect = 0.083
 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 26/121 (21%)

Query: 120 TMPP-----TSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQ 174
           T PP     +S+R  +PE    GGPGGL    G+EEEE+EEEE      D          
Sbjct: 12  TSPPGGVVLSSFRSRDPEE--GGGPGGLVVGGGQEEEEEEEEEAPVSVWD---------- 59

Query: 175 DSHAPLRDSRGSSFEMTDDDSAIRALTQF-PLPKNLLAKVIQIATSSSTAKNLMQFHTVG 233
                  +  G+ F +T      R L    P+P    ++ ++  T  +  ++L+   T G
Sbjct: 60  ------EEEDGAVFTVT--SRQYRPLDPLVPMPPPRSSRRLRAGTLEALVRHLLDTRTSG 111

Query: 234 T 234
           T
Sbjct: 112 T 112


>gi|32455236 helicase (DNA) B [Homo sapiens]
          Length = 1087

 Score = 37.4 bits (85), Expect = 0.083
 Identities = 18/42 (42%), Positives = 26/42 (61%)

Query: 390 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQL 431
           Q+  ++P+D  +   L  I  +PV VISG  GCGKTT + +L
Sbjct: 447 QDQVEVPLDRDQVAALEMICSNPVTVISGKGGCGKTTIVSRL 488


>gi|149408122 RNA helicase LGP2 [Homo sapiens]
          Length = 678

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 29/183 (15%)

Query: 620 VLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQ 679
           ++    R     +L +L   Q ++ V  R Q  +G   S        +++   DQ+ + Q
Sbjct: 371 IIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQ-----STHMTQRDQQEVIQ 425

Query: 680 QPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQ 739
           +   G   +++AT++AE  + I     VV        RY L T          +  +++Q
Sbjct: 426 KFQDGTLNLLVATSVAEEGLDIPHCNVVV--------RYGLLT----------NEISMVQ 467

Query: 740 RRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSK 799
            RGRA   QS +A+     SR  K       E++   LE L+ QA   + +    E+ +K
Sbjct: 468 ARGRARADQSVYAFVATEGSRELKR------ELINEALETLMEQAVAAVQKMDQAEYQAK 521

Query: 800 AVD 802
             D
Sbjct: 522 IRD 524


>gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]
          Length = 745

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 5/109 (4%)

Query: 689 VLATNIAETSITINDIVHV--VDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGR 746
           ++  ++   +I +++I H+   D GL KE     K   S   TV      V+ RRG + +
Sbjct: 194 IVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS-Q 252

Query: 747 CQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVE 795
               ++Y +     L   +PFQ  +  R    N++L+AK+ MP+  + E
Sbjct: 253 SADWWSYGVLMFEMLTGTLPFQGKD--RNETMNMILKAKLGMPQFLSAE 299


>gi|145309298 coiled-coil domain containing 16 [Homo sapiens]
          Length = 372

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 13/98 (13%)

Query: 116 RPEPTMPPTSWRQLNPESIR--PGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQ 173
           +P  +   T++ ++  E IR  P  P GLS     E+EE+EEEE EEG  +        +
Sbjct: 125 QPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEE-EEGDGE------RKR 177

Query: 174 QDSHAPLRDSRGSSFEMTDDDSAIRALTQFPLPKNLLA 211
            D+  PL D++G    +    S+ R +T   LP +  +
Sbjct: 178 GDASKPLSDAQGKEHSV----SSSREVTSSVLPNDFFS 211


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score = 35.0 bits (79), Expect = 0.41
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 12/81 (14%)

Query: 665 VHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKV 724
           +H N    DQ+   +    G  KI++ T+I    + +ND+ HV +        YD    +
Sbjct: 497 LHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYN--------YDFPRNI 548

Query: 725 SCLETVWVSRANVIQRRGRAG 745
                V+V R   I R G+ G
Sbjct: 549 D----VYVHRVGYIGRTGKTG 565


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 34.3 bits (77), Expect = 0.70
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 4/77 (5%)

Query: 149 EEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRDSRGSSFEMTDDDSAI-RALTQFPLPK 207
           EEEE EEEE EEG  +  +FL  +++      +D +    E  D  S I +A+    +PK
Sbjct: 661 EEEEKEEEEEEEGNQETAEFLLSSEE---IETKDEKEMDKENNDGSSEIGKAVGFLSVPK 717

Query: 208 NLLAKVIQIATSSSTAK 224
           +L +    +    S++K
Sbjct: 718 SLSSDSTLLLFKDSSSK 734


>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
           [Homo sapiens]
          Length = 932

 Score = 34.3 bits (77), Expect = 0.70
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 7/92 (7%)

Query: 583 YLEDILAKLGKHQYLHR-HRHHESEDECALDLDLVTDLVLH---IDARGEPGGILCFLPG 638
           YL      LG   +L R + H+++         L+ D+ +H   ++AR     +L F PG
Sbjct: 298 YLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWMDALLAFFPG 357

Query: 639 WQEIKGVQQRLQEALGMHESKYLILPVHSNIP 670
            Q +KG    ++ A+  HE  Y ++  H+ +P
Sbjct: 358 LQVLKG---DIRPAIETHEMLYQVIKKHNFLP 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,874,697
Number of Sequences: 37866
Number of extensions: 2136792
Number of successful extensions: 9848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 9461
Number of HSP's gapped (non-prelim): 195
length of query: 1155
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1042
effective length of database: 13,968,660
effective search space: 14555343720
effective search space used: 14555343720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.