BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens] (509 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens] 1049 0.0 gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens] 1049 0.0 gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens] 1030 0.0 gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens] 974 0.0 gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact... 602 e-172 gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens] 575 e-164 gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens] 512 e-145 gi|93004092 nuclear factor I/B [Homo sapiens] 502 e-142 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 62 2e-09 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 59 1e-08 gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 59 1e-08 gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 59 1e-08 gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 59 1e-08 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 52 1e-06 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 52 1e-06 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 52 1e-06 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 52 2e-06 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 51 2e-06 gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 51 2e-06 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 51 2e-06 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 51 2e-06 gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 51 3e-06 gi|47132519 Ras association and pleckstrin homology domains 1 is... 50 4e-06 gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 50 5e-06 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 50 6e-06 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 50 6e-06 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 50 6e-06 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 50 6e-06 gi|50345997 E1A binding protein p300 [Homo sapiens] 49 8e-06 >gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens] Length = 554 Score = 1049 bits (2713), Expect = 0.0 Identities = 509/509 (100%), Positives = 509/509 (100%) Query: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL Sbjct: 46 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 105 Query: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL Sbjct: 106 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 165 Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA Sbjct: 166 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 225 Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT Sbjct: 226 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285 Query: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS Sbjct: 286 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 345 Query: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS Sbjct: 346 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 405 Query: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN Sbjct: 406 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 465 Query: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST Sbjct: 466 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 525 Query: 481 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 509 SPANRFVSVGPRDPSFVNIPQQTQSWYLG Sbjct: 526 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 554 >gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens] Length = 509 Score = 1049 bits (2713), Expect = 0.0 Identities = 509/509 (100%), Positives = 509/509 (100%) Query: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL Sbjct: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 Query: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL Sbjct: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 Query: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS Sbjct: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300 Query: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS Sbjct: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360 Query: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN Sbjct: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420 Query: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480 Query: 481 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 509 SPANRFVSVGPRDPSFVNIPQQTQSWYLG Sbjct: 481 SPANRFVSVGPRDPSFVNIPQQTQSWYLG 509 >gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens] Length = 501 Score = 1030 bits (2663), Expect = 0.0 Identities = 500/500 (100%), Positives = 500/500 (100%) Query: 10 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ Sbjct: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61 Query: 70 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL Sbjct: 62 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121 Query: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS Sbjct: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181 Query: 190 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 249 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL Sbjct: 182 QSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDL 241 Query: 250 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 309 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG Sbjct: 242 ESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSG 301 Query: 310 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH Sbjct: 302 WHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 361 Query: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN Sbjct: 362 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 421 Query: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 489 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV Sbjct: 422 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 481 Query: 490 GPRDPSFVNIPQQTQSWYLG 509 GPRDPSFVNIPQQTQSWYLG Sbjct: 482 GPRDPSFVNIPQQTQSWYLG 501 >gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens] Length = 498 Score = 974 bits (2519), Expect = 0.0 Identities = 477/494 (96%), Positives = 478/494 (96%) Query: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL Sbjct: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 Query: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL Sbjct: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT Sbjct: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 Query: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS Sbjct: 241 GPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRS 300 Query: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS Sbjct: 301 PGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRAS 360 Query: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN Sbjct: 361 PHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPN 420 Query: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP Sbjct: 421 GSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPILVPGIK 480 Query: 481 SPANRFVSVGPRDP 494 A+ P DP Sbjct: 481 VAASHHPPDRPPDP 494 >gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor) [Homo sapiens] Length = 441 Score = 602 bits (1553), Expect = e-172 Identities = 311/422 (73%), Positives = 350/422 (82%), Gaps = 13/422 (3%) Query: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 MYSP CLTQDEFHPFIEALLPHVRAF+YTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL Sbjct: 1 MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 60 Query: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 L EKPE+KQKWASRLLAKLRKDIRPE+REDFVLT+TGKKPPCCVLSNPDQKGK+RRIDCL Sbjct: 61 LGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCL 120 Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 RQADKVWRLDLVMVILFKGIPLESTDGERL KSPQCSNPGLCVQPHHIGV++KELDLYLA Sbjct: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLA 180 Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 YFVH +S QS+S +Q DADIK P NGHL FQD FVTSGV++VTELVRVSQTP+A + Sbjct: 181 YFVHTPESGQSDSSNQQGDADIKPLP-NGHLSFQDCFVTSGVWNVTELVRVSQTPVATAS 239 Query: 241 GPNFSLSDLESSSYYSMSPGAM-RRSLPSTSSTSSTKRLKSVED-EMDSPGEEPFYTGQG 298 GPNFSL+DLES SYY+++ + RRS+ S STS+TKR KS++D EM+SP ++ FY G G Sbjct: 240 GPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTG 299 Query: 299 RSPGSG-SQSSGW-HEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG 356 RSP +G SQSSGW ++V+ G P +LKKS K F S SQ SS AFT H PV+ G Sbjct: 300 RSPAAGSSQSSGWPNDVDAG---PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAG 356 Query: 357 PR-ASPHATPSTLHFPTSPIIQQPGPYFSHPAIRY---HPQETLKEFVQLVCPD-AGQQA 411 R SP AT S LHFP++ IIQQ PYF+HP IRY H Q++LKEFVQ VC D +GQ Sbjct: 357 VRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQAT 416 Query: 412 GQ 413 GQ Sbjct: 417 GQ 418 >gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens] Length = 499 Score = 575 bits (1483), Expect = e-164 Identities = 324/518 (62%), Positives = 378/518 (72%), Gaps = 38/518 (7%) Query: 10 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ Sbjct: 2 DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61 Query: 70 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129 KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL Sbjct: 62 KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121 Query: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189 DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV D+ Sbjct: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181 Query: 190 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247 QS SP +D +D FQ+SFVTSGVFSVTEL++VS+TP+ GTGPNFSL Sbjct: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241 Query: 248 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 304 +L+ Y ++P + +RR+LPSTSS+ S + + S+E+++D+ +YT SP S Sbjct: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 297 Query: 305 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 359 + SS W E +E G+ SP + +KS F+SPSP + L ++FTQHHRPVI +G Sbjct: 298 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 356 Query: 360 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 414 SPH + S LHFPT+ I+ Q YF H AIRY +PQ+ LK+ V L C A QQ G + Sbjct: 357 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415 Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPTS 472 NGS Q K+ + L ML PPPP P +A P P TKP TTS EGGA SPTS Sbjct: 416 -----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPTS 464 Query: 473 PTYSTPSTSPANR-FVSVGPRDPSFVNIPQQTQSWYLG 509 P+YS P TSPANR FV +GPRDP+ + Q QSWYLG Sbjct: 465 PSYSPPDTSPANRSFVGLGPRDPAGI---YQAQSWYLG 499 >gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens] Length = 428 Score = 512 bits (1318), Expect = e-145 Identities = 278/430 (64%), Positives = 325/430 (75%), Gaps = 21/430 (4%) Query: 3 SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLS 62 SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL Sbjct: 4 SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63 Query: 63 EKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQ 122 EKPEVKQKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQ Sbjct: 64 EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123 Query: 123 ADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYF 182 ADKVWRLDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYF Sbjct: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183 Query: 183 VHAADSSQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 V D+ QS SP +D +D FQ+SFVTSGVFSVTEL++VS+TP+ GT Sbjct: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243 Query: 241 GPNFSLSDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQ 297 GPNFSL +L+ Y ++P + +RR+LPSTSS+ S + + S+E+++D+ +YT Sbjct: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT-- 301 Query: 298 GRSPGSGSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI- 354 SP S + SS W E +E G+ SP + +KS F+SPSP + L ++FTQHHRPVI Sbjct: 302 --SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIA 358 Query: 355 --TGPRASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 407 +G SPH + S LHFPT+ I+ Q YF H AIRY +PQ+ LK+ V L C A Sbjct: 359 VHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 417 Query: 408 GQQAGQVGFL 417 QQ G +L Sbjct: 418 SQQPGPSWYL 427 >gi|93004092 nuclear factor I/B [Homo sapiens] Length = 420 Score = 502 bits (1292), Expect = e-142 Identities = 274/421 (65%), Positives = 313/421 (74%), Gaps = 22/421 (5%) Query: 1 MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDEL 60 MYSP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSK+EERAVKDEL Sbjct: 2 MYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDEL 61 Query: 61 LSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCL 120 LSEKPE+KQKWASRLLAKLRKDIR EYREDFVLTVTGKK PCCVLSNPDQKGK+RRIDCL Sbjct: 62 LSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCL 121 Query: 121 RQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLA 180 RQADKVWRLDLVMVILFKGIPLESTDGERL+KSP C+NP LCVQPHHI VSVKELDL+LA Sbjct: 122 RQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLA 181 Query: 181 YFVHAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240 Y+V DS QS SPS A K+ P G+L +DSFV SGVF+V+ELVRVS+TPI GT Sbjct: 182 YYVQEQDSGQSGSPSHNDPA--KNPP--GYL--EDSFVKSGVFNVSELVRVSRTPITQGT 235 Query: 241 GPNFSLSDLESSSYY-SMSPGA-MRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQG 298 G NF + ++ S YY M+ G ++RSL S S+ K + S+++ M+ FY Sbjct: 236 GVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTI-SIDENMEPSPTGDFYPSPS 294 Query: 299 RSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR 358 SP +GS++ WHE + M SPTT+KK EK FSS SP +S + F QHH P I G Sbjct: 295 -SPAAGSRT--WHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVA 351 Query: 359 ASPHAT-----PSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAG 408 S +T PS L FPT I+ P YFSHP IRY +PQ+TLK +V P + Sbjct: 352 HSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSP 411 Query: 409 Q 409 Q Sbjct: 412 Q 412 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 61.6 bits (148), Expect = 2e-09 Identities = 98/366 (26%), Positives = 132/366 (36%), Gaps = 26/366 (7%) Query: 141 PLESTDGERLVKSPQCSNPGLCVQPHHIGVSV----KELDLYLAYFVHAADSSQSESPSQ 196 P + G SP +PG + P + S + Y + +S S SP+ Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626 Query: 197 PSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYS 256 PS + + TS +S T +P + T P++S + S SY Sbjct: 1627 PSYSPTSPNYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPT---SPSYSP 1680 Query: 257 MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 316 SP S PS S TS + S SP P T SP S S S P Sbjct: 1681 TSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPT 1737 Query: 317 MPS--PTTLKKSEKSGF---SSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFP 371 PS PT+ S S +SPS S TS + + ++ P T P SP +PS + P Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTP--TSPNYSP-TSPS--YSP 1792 Query: 372 TSPIIQQPGPYFSHPAIRYHPQE-TLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430 TSP P +S + RY PQ T P + + P S Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPE 1852 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 490 + PT P P + P P + PT S SPTSPTYS S Sbjct: 1853 YTPTSPKYSPTSPKYSPTSPKYSPTS--PTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYS 1910 Query: 491 PRDPSF 496 P P++ Sbjct: 1911 PTSPTY 1916 Score = 58.5 bits (140), Expect = 1e-08 Identities = 85/307 (27%), Positives = 111/307 (36%), Gaps = 37/307 (12%) Query: 188 SSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247 +S S SP+ PS + + TS +S T +P + T PN+S + Sbjct: 1695 TSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1751 Query: 248 DLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQS 307 S +Y SP S PS S TS S SP P T SP S S S Sbjct: 1752 ---SPNYTPTSPSYSPTS-PSYSPTSPNYTPTSPNYSPTSPSYSP--TSPSYSPTSPSYS 1805 Query: 308 SGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPST 367 P SPT S SSPS S TS T + + P +SP TP++ Sbjct: 1806 PSSPRYTP--QSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSP------SSPEYTPTS 1857 Query: 368 LHF-PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 426 + PTSP P +S + Y P + +P S Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTP-----------------KYSPTSPTYSPTSP 1900 Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRF 486 V+ P P P P P P T PT S +G SPTSP YS S + + Sbjct: 1901 VYTPTSPK-YSPTSPTYSPTSPKYSPTSPTYSPT-SPKGSTYSPTSPGYSPTSPTYSLTS 1958 Query: 487 VSVGPRD 493 ++ P D Sbjct: 1959 PAISPDD 1965 Score = 53.1 bits (126), Expect = 6e-07 Identities = 70/265 (26%), Positives = 97/265 (36%), Gaps = 39/265 (14%) Query: 232 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEE 291 + TP G P + S M+PGA S PS +S +S SPG Sbjct: 1516 AMTPWNQGATPAYGAWSPSVGS--GMTPGAAGFS-PSAASDASGF----------SPGYS 1562 Query: 292 PFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHR 351 P ++ SPGS SS P +PSP G SPS S TS + Sbjct: 1563 PAWSPTPGSPGSPGPSS------PYIPSP--------GGAMSPSYSPTSPA----YEPRS 1604 Query: 352 PVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 411 P P++ ++ S + PTSP P +S + Y P P + + Sbjct: 1605 PGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS------PTSPSYS 1658 Query: 412 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPT 471 +P S + PT P P + P P + P+ S + SPT Sbjct: 1659 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPT 1716 Query: 472 SPTYSTPSTSPANRFVSVGPRDPSF 496 SP+YS S S + S P PS+ Sbjct: 1717 SPSYSPTSPSYSPTSPSYSPTSPSY 1741 Score = 45.8 bits (107), Expect = 9e-05 Identities = 72/273 (26%), Positives = 98/273 (35%), Gaps = 39/273 (14%) Query: 238 AGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRL-KSVEDEMD--SPGEEPFY 294 AGTG L D E Y P ++P + T S M SP P+ Sbjct: 1466 AGTGCFDLLLDAEKCKYGMEIP----TNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWN 1521 Query: 295 TGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS-------SPSPSQTSSLGTAFT 347 G + G+ S S G + PG + S+ SGFS SP+P S G + Sbjct: 1522 QGATPAYGAWSPSVG-SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPS-- 1578 Query: 348 QHHRPVITGPRASPHATPSTLHFPTSPIIQ--QPGPYFSHPAIRYHPQETLKEFVQLVCP 405 P I SP S + PTSP + PG Y + + Y P P Sbjct: 1579 ---SPYIP----SPGGAMSPSYSPTSPAYEPRSPGGY-TPQSPSYSPTS----------P 1620 Query: 406 DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP--PTTST 463 + +PN S ++P P+ P P + P P P+ S Sbjct: 1621 SYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1680 Query: 464 EGGAASPTSPTYSTPSTSPANRFVSVGPRDPSF 496 + SPTSP+YS S S + S P PS+ Sbjct: 1681 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1713 Score = 39.7 bits (91), Expect = 0.007 Identities = 54/197 (27%), Positives = 75/197 (38%), Gaps = 23/197 (11%) Query: 219 TSGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPGAMRRSLPSTSSTSST 275 TS +S T +P + T P++S S S Y+ S + S PS S TS Sbjct: 1779 TSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPK 1838 Query: 276 KRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMP--SPTTLKKSEKSGFSS 333 S SP P T SP S S + P P SPTT K S +S Sbjct: 1839 YTPTSPSYSPSSPEYTP--TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSP----TS 1892 Query: 334 PSPSQTSSLGTAFTQHHRPVI------------TGPRASPHATPSTLHFPTSPIIQQPGP 381 P+ S TS + T + + P T P SP + + + PTSP P Sbjct: 1893 PTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSP 1952 Query: 382 YFSHPAIRYHPQETLKE 398 +S + P ++ +E Sbjct: 1953 TYSLTSPAISPDDSDEE 1969 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%) Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393 PS TSSL + T P + P P P P Q P HPA P Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387 Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453 VQ P + A + + QG+V LPPPPPPP PLP Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434 Query: 454 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 497 P +P + T A P S + TPST+P + P PS V Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478 Score = 32.0 bits (71), Expect = 1.4 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%) Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462 G + S P +P PPPPPP M P PVP PP + Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361 Query: 463 TEGGAASPTSP 473 A P P Sbjct: 362 ALQAPAVPPPP 372 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/51 (33%), Positives = 21/51 (41%) Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 483 P + P PPPPP P L + TST P P +T +PA Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367 Score = 29.6 bits (65), Expect = 6.8 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 439 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 PPPPPPM A+P+P + + A+ +P + +P+ P Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326 >gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%) Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393 PS TSSL + T P + P P P P Q P HPA P Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387 Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453 VQ P + A + + QG+V LPPPPPPP PLP Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434 Query: 454 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 497 P +P + T A P S + TPST+P + P PS V Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478 Score = 32.0 bits (71), Expect = 1.4 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%) Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462 G + S P +P PPPPPP M P PVP PP + Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361 Query: 463 TEGGAASPTSP 473 A P P Sbjct: 362 ALQAPAVPPPP 372 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/51 (33%), Positives = 21/51 (41%) Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 483 P + P PPPPP P L + TST P P +T +PA Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367 Score = 29.6 bits (65), Expect = 6.8 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 439 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 PPPPPPM A+P+P + + A+ +P + +P+ P Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326 >gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%) Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393 PS TSSL + T P + P P P P Q P HPA P Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387 Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453 VQ P + A + + QG+V LPPPPPPP PLP Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434 Query: 454 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 497 P +P + T A P S + TPST+P + P PS V Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478 Score = 32.0 bits (71), Expect = 1.4 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%) Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462 G + S P +P PPPPPP M P PVP PP + Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361 Query: 463 TEGGAASPTSP 473 A P P Sbjct: 362 ALQAPAVPPPP 372 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/51 (33%), Positives = 21/51 (41%) Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 483 P + P PPPPP P L + TST P P +T +PA Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367 Score = 29.6 bits (65), Expect = 6.8 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 439 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 PPPPPPM A+P+P + + A+ +P + +P+ P Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326 >gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 51/164 (31%), Positives = 62/164 (37%), Gaps = 17/164 (10%) Query: 334 PSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQ 393 PS TSSL + T P + P P P P Q P HPA P Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA----PP 387 Query: 394 ETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPV 453 VQ P + A + + QG+V LPPPPPPP PLP Sbjct: 388 PIAPPLVQ-PSPPVARAAPVCETVPVHPLPQGEVQG-------LPPPPPPP-----PLPP 434 Query: 454 PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFV 497 P +P + T A P S + TPST+P + P PS V Sbjct: 435 PGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQV 478 Score = 32.0 bits (71), Expect = 1.4 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 12/71 (16%) Query: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPPP------------PMARPVPLPVPDTKPPTTS 462 G + S P +P PPPPPP M P PVP PP + Sbjct: 302 GLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAT 361 Query: 463 TEGGAASPTSP 473 A P P Sbjct: 362 ALQAPAVPPPP 372 Score = 32.0 bits (71), Expect = 1.4 Identities = 17/51 (33%), Positives = 21/51 (41%) Query: 433 PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPA 483 P + P PPPPP P L + TST P P +T +PA Sbjct: 317 PVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPA 367 Score = 29.6 bits (65), Expect = 6.8 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 439 PPPPPPM-----ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 PPPPPPM A+P+P + + A+ +P + +P+ P Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP 326 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 54.7 bits (130), Expect = 2e-07 Identities = 75/301 (24%), Positives = 103/301 (34%), Gaps = 61/301 (20%) Query: 232 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 290 S P GP S+S S SP A RR S +++ L S + SP Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245 Query: 291 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPT------TLKKSEKSGFSSPSPSQ--- 338 P G R+P SQ G + P +P L S ++PSPS Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305 Query: 339 ---------------------TSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 377 T+SLG+ Q + P SP ATP P +P Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP----PQAP--- 358 Query: 378 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 437 P + P ++ P P A + +P + VH L P Sbjct: 359 ---PALALPPLQAPPS-----------PPASPPLSPLATPSPQAPNALAVH--LLQAPFS 402 Query: 438 PPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRD 493 PPP PP P + P PV P PP+ + AA P S P++ P + + P+ Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462 Query: 494 P 494 P Sbjct: 463 P 463 Score = 43.1 bits (100), Expect = 6e-04 Identities = 59/255 (23%), Positives = 93/255 (36%), Gaps = 34/255 (13%) Query: 250 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306 E+ ++S GA R + P T S + +R ++ E+ P P + + G Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199 Query: 307 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 365 S E PSP ++ S G P+ SS T + P +GP A TP Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS---PARSGPSA--RGTP 254 Query: 366 STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 425 P+ P + G P PQ T P A +G L+ + + Sbjct: 255 RAPAHPSQP--KPKGLQALRP-----PQVT---------PPRKDAAPALGPLSSSPLAT- 297 Query: 426 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANR 485 P+P PP P P + LP P PP+ +T + T+S + P + Sbjct: 298 -------PSPSAPPSPSAPPSLQT-LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349 Query: 486 FVSVGPRDPSFVNIP 500 + P+ P + +P Sbjct: 350 LATPPPQAPPALALP 364 Score = 36.2 bits (82), Expect = 0.073 Identities = 62/259 (23%), Positives = 88/259 (33%), Gaps = 47/259 (18%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317 SP A S +TS S T L++ + SP P T ++P + + + P Sbjct: 317 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 367 Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 365 P+ S ++PSP ++L F+ P + P SP ATP Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427 Query: 366 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 409 + L P SP P P + P + P + K Q P A Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 485 Query: 410 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPPPPPMARPVPLPVPDTKPPTTST 463 +P S G+ PF P+ LP PPP P PL PP + T Sbjct: 486 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 Query: 464 EGGAASPTSPTYSTPSTSP 482 P +P T + P Sbjct: 544 LQAPRRPPTPGPDTSVSGP 562 Score = 30.8 bits (68), Expect = 3.0 Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 36/195 (18%) Query: 332 SSPSPSQTSSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQQPG---PYFSHPA 387 + P P +L T Q P + P +P + ++L P SP+ P P + P Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPL 531 Query: 388 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMAR 447 ++ P +Q A ++ P V P L + P PPPPP Sbjct: 532 LQVPPSPPASPTLQ-----APRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRS 579 Query: 448 P-VPLPVPDTKPPTTST--------------EGGAASPTSPTYSTPSTSPANRFVSVGPR 492 P L PD ++S EGGAA+ P + PA S GP Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPA 637 Query: 493 DP-SFVNIPQQTQSW 506 P +F P W Sbjct: 638 PPLAFRGAPGAPLPW 652 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 52.0 bits (123), Expect = 1e-06 Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%) Query: 225 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 282 + E +R S +P AA T N S ++ S + A S P S+ +++ S Sbjct: 48 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 104 Query: 283 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 336 +E D + T + P S S+ G + G P + + +S S PSP Sbjct: 105 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 164 Query: 337 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 388 SS Q P + TG +P + P P +P + PGP S A+ Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 219 Query: 389 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 448 PQ + P A Q Q P + H P L P PP P Sbjct: 220 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 260 Query: 449 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 P P P PP G A P++P+++ P Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 290 Score = 47.4 bits (111), Expect = 3e-05 Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%) Query: 291 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 336 +P GQG PG S +G PG P P L G + SP+ P Sbjct: 289 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 347 Query: 337 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 395 + S+L + +P+ P A PH P PT+PI Q P P HP P Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 403 Query: 396 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 442 L P A + + +P + + P +P PP PPP Sbjct: 404 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462 Query: 443 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 491 P P L +PP GG T PT + ST PA S P Sbjct: 463 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 514 Score = 33.5 bits (75), Expect = 0.47 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%) Query: 242 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 301 P + SD +SS+ M T T + ++ +PG P T P Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 220 Query: 302 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 350 GS ++ +P P+ P + S P PS H Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 269 Query: 351 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 402 P+ +TG P A HA P LH P P Q GP HP P + Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 319 Query: 403 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 458 + P A Q +G P+ S Q L + P P P P PL +P KP Sbjct: 320 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 376 Query: 459 PTTSTEGGAASPTS----PTYSTPSTSPAN 484 P T+ +P + P S PS N Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 52.0 bits (123), Expect = 1e-06 Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%) Query: 225 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 282 + E +R S +P AA T N S ++ S + A S P S+ +++ S Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658 Query: 283 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 336 +E D + T + P S S+ G + G P + + +S S PSP Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718 Query: 337 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 388 SS Q P + TG +P + P P +P + PGP S A+ Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773 Query: 389 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 448 PQ + P A Q Q P + H P L P PP P Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814 Query: 449 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 P P P PP G A P++P+++ P Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 844 Score = 47.4 bits (111), Expect = 3e-05 Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%) Query: 291 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 336 +P GQG PG S +G PG P P L G + SP+ P Sbjct: 843 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901 Query: 337 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 395 + S+L + +P+ P A PH P PT+PI Q P P HP P Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957 Query: 396 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 442 L P A + + +P + + P +P PP PPP Sbjct: 958 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016 Query: 443 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 491 P P L +PP GG T PT + ST PA S P Sbjct: 1017 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068 Score = 33.5 bits (75), Expect = 0.47 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%) Query: 242 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 301 P + SD +SS+ M T T + ++ +PG P T P Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774 Query: 302 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 350 GS ++ +P P+ P + S P PS H Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 823 Query: 351 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 402 P+ +TG P A HA P LH P P Q GP HP P + Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 873 Query: 403 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 458 + P A Q +G P+ S Q L + P P P P PL +P KP Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 930 Query: 459 PTTSTEGGAASPTS----PTYSTPSTSPAN 484 P T+ +P + P S PS N Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 52.0 bits (123), Expect = 1e-06 Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 43/270 (15%) Query: 225 VTELVRVS--QTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVE 282 + E +R S +P AA T N S ++ S + A S P S+ +++ S Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEA---SSPLKSNKRQREKVASDT 658 Query: 283 DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEV-----EPGMPSPTTLKKSEKSGFSS-PSP 336 +E D + T + P S S+ G + G P + + +S S PSP Sbjct: 659 EEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSP 718 Query: 337 SQT-----SSLGTAFTQHHRPVI---TGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAI 388 SS Q P + TG +P + P P +P + PGP S A+ Sbjct: 719 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-----PGTPQLPTPGPTPSATAV 773 Query: 389 RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP 448 PQ + P A Q Q P + H P L P PP P Sbjct: 774 P--PQGS---------PTASQAPNQ-----PQAPTAPVPHTHIQQAPALHPQRPPS---P 814 Query: 449 VPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 P P P PP G A P++P+++ P Sbjct: 815 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQP 844 Score = 47.4 bits (111), Expect = 3e-05 Identities = 62/232 (26%), Positives = 80/232 (34%), Gaps = 37/232 (15%) Query: 291 EPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFS----SPS----------P 336 +P GQG PG S +G PG P P L G + SP+ P Sbjct: 843 QPPLHGQG-PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP 901 Query: 337 SQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPY-FSHPAIRYHPQET 395 + S+L + +P+ P A PH P PT+PI Q P P HP P Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPF 957 Query: 396 LKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH-----NPFLPTPMLPP--------PPP 442 L P A + + +P + + P +P PP PPP Sbjct: 958 SMN-ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016 Query: 443 PPMARPVPLPVPDTKPPTTS---TEGGAASPTSPTYSTPSTSPANRFVSVGP 491 P P L +PP GG T PT + ST PA S P Sbjct: 1017 PASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQP 1068 Score = 33.5 bits (75), Expect = 0.47 Identities = 66/270 (24%), Positives = 89/270 (32%), Gaps = 54/270 (20%) Query: 242 PNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSP 301 P + SD +SS+ M T T + ++ +PG P T P Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---P 774 Query: 302 GSGSQSSGWHEVEPGMPS-----------PTTLKKSEKSGFSSPSPSQTSSLGTAFTQHH 350 GS ++ +P P+ P + S P PS H Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-----------H 823 Query: 351 RPV--ITG----PRASPHATPSTLHF--PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQL 402 P+ +TG P A HA P LH P P Q GP HP P + Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPP-LHGQGPPGPHSLQAGPLLQHPG----PPQPFG----- 873 Query: 403 VCPDAGQQAGQVGF----LNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKP 458 + P A Q +G P+ S Q L + P P P P PL +P KP Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP---PAPLAMPHIKP 930 Query: 459 PTTSTEGGAASPTS----PTYSTPSTSPAN 484 P T+ +P + P S PS N Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 51.6 bits (122), Expect = 2e-06 Identities = 61/262 (23%), Positives = 93/262 (35%), Gaps = 28/262 (10%) Query: 240 TGPNFSLSDLESSSYYSMSPGAMRRSLPS-----TSSTSSTKRLKSVEDEMDSPGEEPFY 294 T P+F+LS +SS +++P LP+ TS S+ + S+ + E Sbjct: 1065 TSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTT 1124 Query: 295 TGQGRSPGSGSQSSGWHEVEPG-MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 353 +P S + S +P P PTT + +P ++L T H P Sbjct: 1125 PDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDP------TMAPDPITTLNPTVTPHF-PT 1177 Query: 354 ITGPRASPHATPST--LHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 411 P +PH T T P QP +H + P T + F + Sbjct: 1178 TPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237 Query: 412 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPP---------PPPMARPVPL--PVPDTKPPT 460 P+ ++ H+ +P P P P P P P P P P T P Sbjct: 1238 TPHPTTTPHPTTI--THSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHP 1295 Query: 461 TSTEGGAASPTSPTYSTPSTSP 482 T+T +P T P+T+P Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTTP 1317 Score = 38.1 bits (87), Expect = 0.019 Identities = 54/240 (22%), Positives = 73/240 (30%), Gaps = 34/240 (14%) Query: 296 GQGRSPGS----------GSQSSGWHEVEPGMPS-----PTTLKKSEKSGFSSPSPSQTS 340 G RSPGS GS W E P P+ P T + P P+ TS Sbjct: 965 GTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTS 1024 Query: 341 SLGTAFTQHHRPVITGPRASPHATPSTLH--FPTSPIIQQPGPYFSH--------PAIRY 390 T H +P +P T T+P + P F+ PA+ Sbjct: 1025 DSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTP 1084 Query: 391 HPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN-PFLPTPMLPP--------PP 441 P T + +V L+P + P L T P Sbjct: 1085 EPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPD 1144 Query: 442 PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQ 501 P P P P P P +T +P PT P+T+P ++ P PQ Sbjct: 1145 PSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQ 1204 Score = 34.7 bits (78), Expect = 0.21 Identities = 43/184 (23%), Positives = 65/184 (35%), Gaps = 25/184 (13%) Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQ 377 P PTT + + +P T++ T H P P ++P T T+ PTS + Sbjct: 1293 PHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPH--PTTPDPSSTPVIT--TVSLPTSLGTE 1348 Query: 378 QPGPYFSHPAIR--YHPQETLKEFVQLVCPDAGQQAGQVGFL--------NPNGSSQGKV 427 P + P ++ HPQ T P Q+ L +P+ SS Sbjct: 1349 LSSPTLA-PTVKPSLHPQLTF------TAPAPHTSTSQIPTLEPSPALESSPSRSSTATS 1401 Query: 428 HNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFV 487 +P PP P P P P + T + SPT+ P P + Sbjct: 1402 MDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDP----L 1457 Query: 488 SVGP 491 ++GP Sbjct: 1458 TLGP 1461 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 51.2 bits (121), Expect = 2e-06 Identities = 75/310 (24%), Positives = 101/310 (32%), Gaps = 49/310 (15%) Query: 232 SQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRR-SLPSTSSTSSTKRLKSVEDEMDSPGE 290 S P GP S+S S SP A RR S +++ L S + SP Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254 Query: 291 E-PFYTGQGRSPGSGSQSS--GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFT 347 P G R+P SQ G + P +P + G S SP T S A Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314 Query: 348 QHHRPVITG---------------PRA--SPHATPSTLHFPT--------------SPII 376 P + P A SP A PS P+ SP + Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374 Query: 377 QQPGPYFSHPAI--------RYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH 428 Q + P + + P L P A + +P + VH Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434 Query: 429 NPFLPTPMLPPPPPP---PMARPVPLPV-PDTKPPTTSTEGGAASPTSPTYSTPSTSPAN 484 L P PPP PP P + P PV P PP+ + AA P S P++ P + Sbjct: 435 --LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492 Query: 485 RFVSVGPRDP 494 + P+ P Sbjct: 493 PSATPPPQAP 502 Score = 46.6 bits (109), Expect = 5e-05 Identities = 67/271 (24%), Positives = 96/271 (35%), Gaps = 36/271 (13%) Query: 250 ESSSYYSMSPGAMRRS---LPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306 E+ ++S GA R + P T S + +R ++ E+ P P + + G Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208 Query: 307 SSGWHEVEPGMPSPTTLKK-SEKSGFSSPSPSQTSSLGTAFTQHHR--PVITG-PRASPH 362 S E PSP ++ S G P+ SS T + R P G PRA H Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268 Query: 363 AT---PSTLHFPTSPIIQQP--------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQQA 411 + P L P + P GP S P P L+ P Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP------ 322 Query: 412 GQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPV--PLPVPDTKPPTTSTEGGAAS 469 P+ SS L TP LP PP P A P LP P PP+ +T + Sbjct: 323 -----ATPHSSSL----TCQLATP-LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372 Query: 470 PTSPTYSTPSTSPANRFVSVGPRDPSFVNIP 500 T+S + P + + P+ P + +P Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALP 403 Score = 36.2 bits (82), Expect = 0.073 Identities = 62/259 (23%), Positives = 88/259 (33%), Gaps = 47/259 (18%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317 SP A S +TS S T L++ + SP P T ++P + + + P Sbjct: 356 SPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQ 406 Query: 318 PSPTTLKKSEKSGFSSPSPSQTSSLGT-----AFTQHHRPVI-------TGPRASPHATP 365 P+ S ++PSP ++L F+ P + P SP ATP Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466 Query: 366 ST----------LHFPTSPIIQQP------GPYFSHPAIRYHPQETLKEFVQLVCPDAGQ 409 + L P SP P P + P + P + K Q P A Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ--APPALA 524 Query: 410 QAGQVGFLNPNGSSQGKVHNPFLPTPMLP------PPPPPPMARPVPLPVPDTKPPTTST 463 +P S G+ PF P+ LP PPP P PL PP + T Sbjct: 525 TPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582 Query: 464 EGGAASPTSPTYSTPSTSP 482 P +P T + P Sbjct: 583 LQAPRRPPTPGPDTSVSGP 601 Score = 30.8 bits (68), Expect = 3.0 Identities = 48/195 (24%), Positives = 68/195 (34%), Gaps = 36/195 (18%) Query: 332 SSPSPSQTSSLGTAFTQH-HRPVITGPRASPHATPSTLHFPTSPIIQQPG---PYFSHPA 387 + P P +L T Q P + P +P + ++L P SP+ P P + P Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAAPL 570 Query: 388 IRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMAR 447 ++ P +Q A ++ P V P L + P PPPPP Sbjct: 571 LQVPPSPPASPTLQ-----APRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRS 618 Query: 448 P-VPLPVPDTKPPTTST--------------EGGAASPTSPTYSTPSTSPANRFVSVGPR 492 P L PD ++S EGGAA+ P + PA S GP Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPA 676 Query: 493 DP-SFVNIPQQTQSW 506 P +F P W Sbjct: 677 PPLAFRGAPGAPLPW 691 >gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] Length = 548 Score = 51.2 bits (121), Expect = 2e-06 Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%) Query: 184 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 243 H A + + P P A K + + +L + + + P+ A G Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332 Query: 244 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 303 + +S + P A + P S S+T+ P + G P Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375 Query: 304 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 363 G H PG P F P PS T G QH+ P P Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421 Query: 364 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 423 P + P P+ Q P HP + P P Q G P GS Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459 Query: 424 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 QGK P P M+PPPPPPP +P P P PP + P P+ S Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518 Query: 479 STSP 482 S++P Sbjct: 519 SSTP 522 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 51.2 bits (121), Expect = 2e-06 Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%) Query: 184 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 243 H A + + P P A K + + +L + + + P+ A G Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332 Query: 244 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 303 + +S + P A + P S S+T+ P + G P Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375 Query: 304 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 363 G H PG P F P PS T G QH+ P P Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421 Query: 364 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 423 P + P P+ Q P HP + P P Q G P GS Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459 Query: 424 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 QGK P P M+PPPPPPP +P P P PP + P P+ S Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518 Query: 479 STSP 482 S++P Sbjct: 519 SSTP 522 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 51.2 bits (121), Expect = 2e-06 Identities = 72/304 (23%), Positives = 98/304 (32%), Gaps = 73/304 (24%) Query: 184 HAADSSQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPN 243 H A + + P P A K + + +L + + + P+ A G Sbjct: 287 HIASDCKFQRPGDPQSAQDKARMDKEYLSL--------------MAELGEAPVPASVGST 332 Query: 244 FSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGS 303 + +S + P A + P S S+T+ P + G P Sbjct: 333 SGPATTPLAS--APRPAAPANNPPPPSLMSTTQ-------------SRPPWMNSG--PSE 375 Query: 304 GSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHA 363 G H PG P F P PS T G QH+ P P Sbjct: 376 SRPYHGMHGGGPGGPG------GGPHSFPHPLPSLTGGHGGHPMQHN------PNGPP-- 421 Query: 364 TPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSS 423 P + P P+ Q P HP + P P Q G P GS Sbjct: 422 -PPWMQPPPPPMNQGP-----HPPGHHGP------------PPMDQYLGST----PVGSG 459 Query: 424 -----QGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 QGK P P M+PPPPPPP +P P P PP + P P+ S Sbjct: 460 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMA 518 Query: 479 STSP 482 S++P Sbjct: 519 SSTP 522 Score = 35.4 bits (80), Expect = 0.12 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 6/59 (10%) Query: 430 PFLPTPMLPPPPPPP------MARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 P LP PPPPPPP M P P P P P T G P + P P Sbjct: 575 PPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633 >gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 673 Score = 50.8 bits (120), Expect = 3e-06 Identities = 73/291 (25%), Positives = 101/291 (34%), Gaps = 56/291 (19%) Query: 220 SGVFSVTELVRVSQTPIAAGTGPNFSLSD---LESSSYYSMSPG--AMRRSLPSTSSTSS 274 +G+ S T L ++ T T S + S + SM+P ++ R LP S T Sbjct: 257 TGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGM 316 Query: 275 TKRLKSVE-DEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPT-TLKKSEKSGFS 332 R + D S P R+P S + +P SPT T ++ +G Sbjct: 317 LSRTSLTKMDSTASISRTPPRASITRTPSRASPTG-----KPSTASPTGTPSRASPTG-- 369 Query: 333 SPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHP 392 SPS S G + T P T PRASP TPST P P S +I Sbjct: 370 --SPSTASLTGLSSTAS--PTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSI---- 421 Query: 393 QETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLP 452 + +P P P PP A P P Sbjct: 422 -----------------------------TKMDSTASPTRTPPRASPTGTPPRASPTGTP 452 Query: 453 VPDTKPPTTSTEGGAASPT-SPTYSTPSTSPANRFVSVGPRDPSFVNIPQQ 502 + T ST ASPT SP+ ++P+ SP+ + P S P + Sbjct: 453 SRASPTGTQST----ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSR 499 Score = 37.4 bits (85), Expect = 0.033 Identities = 74/319 (23%), Positives = 104/319 (32%), Gaps = 28/319 (8%) Query: 189 SQSESPSQPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLSD 248 S++ PS A + P L +G S L+ GT P SL Sbjct: 9 SRASPTRTPSTASLTGTPSRASL--------TGTPSTASLMGTPSRASLTGTPPRASLKG 60 Query: 249 LESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSS 308 S + +SP R SL S+S R S+ P R+ S+ Sbjct: 61 TTSMASLMVSPS--RASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPST 118 Query: 309 GWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITG--PRASPHATPS 366 P S TT S S S T S A T R +T PRAS TPS Sbjct: 119 ASLTRSPSRASLTTTP-------SRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPS 171 Query: 367 TLHFPTSPIIQQPG--PYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQ 424 T +P P P + P K +A G P S Sbjct: 172 TASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTG-TPPRASPT 230 Query: 425 GKVHNPFLPTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPST 480 G P M+P PP A P + + ST +P+ P+ ++P+ Sbjct: 231 GS--PPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTG 288 Query: 481 SPANRFVSVGPRDPSFVNI 499 +P+ +S+ P S + + Sbjct: 289 TPSRASLSMTPSTASLMRM 307 Score = 37.0 bits (84), Expect = 0.043 Identities = 60/247 (24%), Positives = 84/247 (34%), Gaps = 48/247 (19%) Query: 237 AAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGE-EPFYT 295 A+ TG + S S S S + R SL T S +S +++S +P P +T Sbjct: 464 ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWT 523 Query: 296 GQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT 355 SP +GS S+ + G PS L ++ + +PS+ S + T Sbjct: 524 PSTASP-TGSPSTA---LAMGSPSRAALTRTPSRASLTRTPSRAS------------LTT 567 Query: 356 GPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 415 RAS TPST+ P P S + P L Sbjct: 568 PSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSAL------------------- 608 Query: 416 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTY 475 L S+ P P P PP A P T P ++ G SPT Sbjct: 609 -LTKMDSTASITRTP----PRASPTETPPRASP-------TGTPPRASPTGTPPRASPTG 656 Query: 476 STPSTSP 482 + P SP Sbjct: 657 TPPRASP 663 Score = 30.0 bits (66), Expect = 5.2 Identities = 49/198 (24%), Positives = 68/198 (34%), Gaps = 26/198 (13%) Query: 188 SSQSESPS-QPSDADIKDQPENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAG-TGPNFS 245 S + SP+ PS A + P L +S T+ + + TP A TG Sbjct: 478 SPSTASPTGSPSRASLTRTPSRASLTKMES--TASITRTPSRASPTWTPSTASPTG---- 531 Query: 246 LSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGS 305 S + + S S A+ R+ S T + R S P R P S S Sbjct: 532 -SPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSAS 590 Query: 306 QSSGWHEVEP-GMPSPTTLKKSEKSGFSSPSPSQTS----------------SLGTAFTQ 348 + P GMPS L K + + + +P + S + T Sbjct: 591 PTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPP 650 Query: 349 HHRPVITGPRASPHATPS 366 P T PRASP TPS Sbjct: 651 RASPTGTPPRASPTGTPS 668 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 50.4 bits (119), Expect = 4e-06 Identities = 54/220 (24%), Positives = 80/220 (36%), Gaps = 20/220 (9%) Query: 257 MSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPG 316 + P A + L + + +STK + V + P P + P + P Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832 Query: 317 MPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPII 376 +P P ++S + P PS S + + Q I P P+ P P+ Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-----IASQFPPPPTPPAMESQPLKPVP 887 Query: 377 QQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPM 436 P S PA++ P+ + + PD P V P P+P+ Sbjct: 888 ANVAPQ-SPPAVKAKPKWQPSS-IPVPSPD----------FPPPPPESSLVFPPPPPSPV 935 Query: 437 -LPPPPPPPMARPVP--LPVPDTKPPTTSTEGGAASPTSP 473 PPPPPPP A P P P K TS+ GG P +P Sbjct: 936 PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975 Score = 46.6 bits (109), Expect = 5e-05 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Query: 417 LNPNGSSQGKVHNPFLPT----PMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTS 472 L P S Q K+ P+ + P+ PPPPPPP P P P P P ++ G+A+P Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664 Query: 473 PTYST 477 YST Sbjct: 665 VKYST 669 Score = 43.5 bits (101), Expect = 5e-04 Identities = 53/209 (25%), Positives = 70/209 (33%), Gaps = 45/209 (21%) Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGP---------------RA 359 P +P+P + K + P+P+ T ++ TQ P T P Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826 Query: 360 SPHATPSTLHFPTSPIIQQ------PGPYFSHPAI------RYHPQET--------LKEF 399 SP P + PT P Q P P P++ ++ P T LK Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV 886 Query: 400 VQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTP------MLPPPPPPPMARPVPLPV 453 V P + P S V +P P P + PPPPP P+ P P P Sbjct: 887 PANVAPQSPPAVKAKPKWQP---SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP-PP 942 Query: 454 PDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 P T PT G TS T S P Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKP 971 Score = 39.3 bits (90), Expect = 0.009 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 12/70 (17%) Query: 426 KVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPP----------TTSTEGGAASPTSPTY 475 K+H T + PP PPPP P+P P+P PP +T T + +P Sbjct: 748 KIHQVQHITQVAPPTPPPP--PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805 Query: 476 STPSTSPANR 485 TP PA + Sbjct: 806 PTPPVPPAKK 815 Score = 37.0 bits (84), Expect = 0.043 Identities = 53/240 (22%), Positives = 81/240 (33%), Gaps = 24/240 (10%) Query: 245 SLSDLESSSYYSMSPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSG 304 S D S S S+ G+ S+P + S S + V D +P + +S S Sbjct: 522 SAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDT------QPAGHVRSQSIVSS 575 Query: 305 SQSSGWHEVEPGMPSPTTLKKSEKSGFSS--PSPSQTSSLGTAFTQHH-RPVITGPRASP 361 S W S +S ++S P S + T +T P + P P Sbjct: 576 VFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP 635 Query: 362 HATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNG 421 P P P+ Q P A + T+ +A Q +G + Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL-----QNASQHSGALFKPPTPP 690 Query: 422 SSQGKVHNPFL---PTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP 478 Q + P + P ++PPPPPPP P P + +P+ P +S P Sbjct: 691 VMQSQSVKPQILVPPNGVVPPPPPPP-------PPPTPGSAMAQLKPAPCAPSLPQFSAP 743 Score = 33.9 bits (76), Expect = 0.36 Identities = 50/188 (26%), Positives = 65/188 (34%), Gaps = 26/188 (13%) Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTS- 373 P P PT +KSG S+TSS G +P T R S + S P Sbjct: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGK-----KPPPTPQRNSSIKSSSGAEHPEPK 993 Query: 374 -PIIQQPGPYFSHPAIRYHP-QETLKEFVQLVCPDAGQ------------QAGQVGFLNP 419 P + F+ PA P +ETL P G+ Q G V P Sbjct: 994 RPSVDSLVSKFTPPAESGSPSKETLPP--PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051 Query: 420 NGSSQGKVHNPFLPTPM----LPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTY 475 S +GK P+P PPPPP P+ +P TS + +P + Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW 1111 Query: 476 STPSTSPA 483 S S A Sbjct: 1112 SKMSVKKA 1119 Score = 29.3 bits (64), Expect = 8.9 Identities = 20/75 (26%), Positives = 26/75 (34%), Gaps = 3/75 (4%) Query: 430 PFLPTPMLPPPPPPPM-ARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 488 P +P P+ P PP P+ P P P T +P P PA+ Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826 Query: 489 VGPRDPSFVNIPQQT 503 P P V +P T Sbjct: 827 SPPTPP--VPVPPPT 839 >gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] Length = 1488 Score = 50.1 bits (118), Expect = 5e-06 Identities = 42/131 (32%), Positives = 55/131 (41%), Gaps = 9/131 (6%) Query: 357 PRASPHATPSTLHFPTSPI-IQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVG 415 P+ +PH LH PTSP+ + P P PA + P+ + + P AG G Sbjct: 1351 PQFAPHGR-HPLHQPTSPLPLYSPAPQHP-PAHKQGPKHFIFSHHPQMMPAAGAAGGPGS 1408 Query: 416 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTK----PPTTSTEGGAASPT 471 P G S H+P P P PP P P+P P P T PPT+ AS Sbjct: 1409 --RPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGP 1466 Query: 472 SPTYSTPSTSP 482 T + PS +P Sbjct: 1467 PGTANPPSANP 1477 Score = 34.7 bits (78), Expect = 0.21 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 4/84 (4%) Query: 408 GQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGA 467 G G +G L S +H + P PPP P +P LP P +PP G Sbjct: 1248 GHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQP-SLPPPPQQPPPLPQLGSI 1306 Query: 468 ASPTSPTYSTPSTSPANRFVSVGP 491 P + S P P F + GP Sbjct: 1307 PPPPA---SAPPVGPHRHFHAHGP 1327 Score = 29.3 bits (64), Expect = 8.9 Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 406 DAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPP 444 DAG++ + + + + +G V + P +PPPPPPP Sbjct: 1149 DAGKRGRRNSVGSLDSTIEGSVISSPRPHQRMPPPPPPP 1187 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 49.7 bits (117), Expect = 6e-06 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 314 +P + + P + ++ + L E +P EEP T + +P + + + Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 550 Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 372 P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT Sbjct: 551 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 S +P P P+E + P P G++ + P Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 657 Query: 433 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 490 TP P P P P KP PTT E +P P +TP PA Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 716 Query: 491 PRDPSFVNIPQQTQ 504 P S V+ P T+ Sbjct: 717 PPTTSEVSTPTTTK 730 Score = 46.6 bits (109), Expect = 5e-05 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%) Query: 318 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 372 P+PTT K + E S ++ P+ T+ A T +P T P+ TP P Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 459 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 430 ++P P P+ET + + P ++ P ++ ++ P Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 482 PTP P P P + P PTT E +P P +TP T+P Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572 Score = 46.2 bits (108), Expect = 7e-05 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%) Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 372 P P+PTT K+ + P+P+ T S T T+ P T P +P+T P Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 427 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 ++P P P+E + P ++ P ++ K P Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 486 Query: 433 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 488 P + P P P +P P P+ PTT E +P P +TP + N Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545 Query: 489 VGPRDP 494 P P Sbjct: 546 PAPTTP 551 Score = 46.2 bits (108), Expect = 7e-05 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317 +P + P+T + K E +P E T +G +P + + + +P Sbjct: 539 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596 Query: 318 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 370 +PTT K+ + P+P T+ GTA T P T P+ +P T P+TL Sbjct: 597 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654 Query: 371 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430 P ++P P P P T + P + P Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 697 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 481 P P P P P P+T PPTT ST PT SP STP S Sbjct: 698 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749 Query: 482 PANRFVSVGPRDP 494 P + + P++P Sbjct: 750 PTPKALENSPKEP 762 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%) Query: 264 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 323 +S P+T+ + KS +P E T + +P + + + P P+PTT Sbjct: 394 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 447 Query: 324 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 377 K+ + P+P+ T A T P T P+ + TP L PT+P + Sbjct: 448 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 504 Query: 378 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 437 +P P P+E + P + A PN + P P P Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 558 Query: 438 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 473 P P P + P PTT E +P P Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594 Score = 40.8 bits (94), Expect = 0.003 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%) Query: 249 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306 +E +S ++P + + P+ + ++TK L + ++ + +EP T + + Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 238 Query: 307 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 366 S+ P P+PTT K + + P+P+ T + P T A P T S Sbjct: 239 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 293 Query: 367 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 426 PT+P ++P P P+E + P ++ + + Sbjct: 294 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 341 Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 P P P P P P + P PTT+ E +P P +T ++P Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397 Score = 40.4 bits (93), Expect = 0.004 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%) Query: 315 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369 P P+PTT K+ E + + P+ T+ A T P T P+ P T + Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 380 Query: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429 PT+P P S P P T + + +P + + Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 430 Query: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 489 P P P P P P + P PTT+ + +P P +TP + + Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490 Query: 490 GPRDP 494 P P Sbjct: 491 TPTTP 495 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 49.7 bits (117), Expect = 6e-06 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 314 +P + + P + ++ + L E +P EEP T + +P + + + Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 591 Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 372 P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT Sbjct: 592 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 S +P P P+E + P P G++ + P Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 698 Query: 433 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 490 TP P P P P KP PTT E +P P +TP PA Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 757 Query: 491 PRDPSFVNIPQQTQ 504 P S V+ P T+ Sbjct: 758 PPTTSEVSTPTTTK 771 Score = 46.6 bits (109), Expect = 5e-05 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%) Query: 318 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 372 P+PTT K + E S ++ P+ T+ A T +P T P+ TP P Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 500 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 430 ++P P P+ET + + P ++ P ++ ++ P Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 482 PTP P P P + P PTT E +P P +TP T+P Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613 Score = 46.2 bits (108), Expect = 7e-05 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%) Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 372 P P+PTT K+ + P+P+ T S T T+ P T P +P+T P Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 468 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 ++P P P+E + P ++ P ++ K P Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 527 Query: 433 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 488 P + P P P +P P P+ PTT E +P P +TP + N Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586 Query: 489 VGPRDP 494 P P Sbjct: 587 PAPTTP 592 Score = 46.2 bits (108), Expect = 7e-05 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317 +P + P+T + K E +P E T +G +P + + + +P Sbjct: 580 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637 Query: 318 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 370 +PTT K+ + P+P T+ GTA T P T P+ +P T P+TL Sbjct: 638 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695 Query: 371 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430 P ++P P P P T + P + P Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 738 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 481 P P P P P P+T PPTT ST PT SP STP S Sbjct: 739 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790 Query: 482 PANRFVSVGPRDP 494 P + + P++P Sbjct: 791 PTPKALENSPKEP 803 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%) Query: 264 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 323 +S P+T+ + KS +P E T + +P + + + P P+PTT Sbjct: 435 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 488 Query: 324 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 377 K+ + P+P+ T A T P T P+ + TP L PT+P + Sbjct: 489 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 545 Query: 378 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 437 +P P P+E + P + A PN + P P P Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 599 Query: 438 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 473 P P P + P PTT E +P P Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635 Score = 40.8 bits (94), Expect = 0.003 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%) Query: 249 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306 +E +S ++P + + P+ + ++TK L + ++ + +EP T + + Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 279 Query: 307 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 366 S+ P P+PTT K + + P+P+ T + P T A P T S Sbjct: 280 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 334 Query: 367 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 426 PT+P ++P P P+E + P ++ + + Sbjct: 335 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 382 Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 P P P P P P + P PTT+ E +P P +T ++P Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438 Score = 40.4 bits (93), Expect = 0.004 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%) Query: 315 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369 P P+PTT K+ E + + P+ T+ A T P T P+ P T + Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 421 Query: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429 PT+P P S P P T + + +P + + Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 471 Query: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 489 P P P P P P + P PTT+ + +P P +TP + + Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531 Query: 490 GPRDP 494 P P Sbjct: 532 TPTTP 536 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 49.7 bits (117), Expect = 6e-06 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 314 +P + + P + ++ + L E +P EEP T + +P + + + Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 643 Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 372 P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT Sbjct: 644 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 S +P P P+E + P P G++ + P Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 750 Query: 433 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 490 TP P P P P KP PTT E +P P +TP PA Sbjct: 751 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 809 Query: 491 PRDPSFVNIPQQTQ 504 P S V+ P T+ Sbjct: 810 PPTTSEVSTPTTTK 823 Score = 46.6 bits (109), Expect = 5e-05 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%) Query: 318 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 372 P+PTT K + E S ++ P+ T+ A T +P T P+ TP P Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 552 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 430 ++P P P+ET + + P ++ P ++ ++ P Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 482 PTP P P P + P PTT E +P P +TP T+P Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665 Score = 46.2 bits (108), Expect = 7e-05 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%) Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 372 P P+PTT K+ + P+P+ T S T T+ P T P +P+T P Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 520 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 ++P P P+E + P ++ P ++ K P Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 579 Query: 433 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 488 P + P P P +P P P+ PTT E +P P +TP + N Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638 Query: 489 VGPRDP 494 P P Sbjct: 639 PAPTTP 644 Score = 46.2 bits (108), Expect = 7e-05 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317 +P + P+T + K E +P E T +G +P + + + +P Sbjct: 632 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689 Query: 318 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 370 +PTT K+ + P+P T+ GTA T P T P+ +P T P+TL Sbjct: 690 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747 Query: 371 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430 P ++P P P P T + P + P Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 790 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 481 P P P P P P+T PPTT ST PT SP STP S Sbjct: 791 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842 Query: 482 PANRFVSVGPRDP 494 P + + P++P Sbjct: 843 PTPKALENSPKEP 855 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%) Query: 264 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 323 +S P+T+ + KS +P E T + +P + + + P P+PTT Sbjct: 487 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 540 Query: 324 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 377 K+ + P+P+ T A T P T P+ + TP L PT+P + Sbjct: 541 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 597 Query: 378 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 437 +P P P+E + P + A PN + P P P Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 651 Query: 438 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 473 P P P + P PTT E +P P Sbjct: 652 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687 Score = 40.8 bits (94), Expect = 0.003 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%) Query: 249 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306 +E +S ++P + + P+ + ++TK L + ++ + +EP T + + Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331 Query: 307 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 366 S+ P P+PTT K + + P+P+ T + P T A P T S Sbjct: 332 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 386 Query: 367 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 426 PT+P ++P P P+E + P ++ + + Sbjct: 387 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 434 Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 P P P P P P + P PTT+ E +P P +T ++P Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490 Score = 40.4 bits (93), Expect = 0.004 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%) Query: 315 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369 P P+PTT K+ E + + P+ T+ A T P T P+ P T + Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 473 Query: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429 PT+P P S P P T + + +P + + Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 523 Query: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 489 P P P P P P + P PTT+ + +P P +TP + + Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583 Query: 490 GPRDP 494 P P Sbjct: 584 TPTTP 588 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 49.7 bits (117), Expect = 6e-06 Identities = 62/254 (24%), Positives = 92/254 (36%), Gaps = 24/254 (9%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPG--EEPF-YTGQGRSPGSGSQSSGWHEVE 314 +P + + P + ++ + L E +P EEP T + +P + + + Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA---PTT 684 Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR--ASPHATPSTLHFPT 372 P P+PTT K+ + +P T+ GTA T P T P+ A P+T PT Sbjct: 685 PKEPAPTTPKEPAPTTPKETAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 S +P P P+E + P P G++ + P Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP-----------TTPKGTAPTTLKEPAP 791 Query: 433 PTPMLPPPPP-PPMARPVPLPVPDTKP-PTTSTEGGAASPTSPTYSTPSTSPANRFVSVG 490 TP P P P P KP PTT E +P P +TP PA Sbjct: 792 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-KPAPTTPETP 850 Query: 491 PRDPSFVNIPQQTQ 504 P S V+ P T+ Sbjct: 851 PPTTSEVSTPTTTK 864 Score = 46.6 bits (109), Expect = 5e-05 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%) Query: 318 PSPTTLKKS-----EKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPT 372 P+PTT K + E S ++ P+ T+ A T +P T P+ TP P Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PA 593 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVH--NP 430 ++P P P+ET + + P ++ P ++ ++ P Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTP-STSP 482 PTP P P P + P PTT E +P P +TP T+P Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706 Score = 46.2 bits (108), Expect = 7e-05 Identities = 44/186 (23%), Positives = 66/186 (35%), Gaps = 9/186 (4%) Query: 315 PGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVIT--GPRASPHATPSTLHFPT 372 P P+PTT K+ + P+P+ T S T T+ P T P +P+T P Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT-TKEPAPTTTKSAPTTPKEPSPTTTKEPA 561 Query: 373 SPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFL 432 ++P P P+E + P ++ P ++ K P Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP-KETAPTT 620 Query: 433 PTPMLPPPP----PPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVS 488 P + P P P +P P P+ PTT E +P P +TP + N Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679 Query: 489 VGPRDP 494 P P Sbjct: 680 PAPTTP 685 Score = 46.2 bits (108), Expect = 7e-05 Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 45/253 (17%) Query: 258 SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGM 317 +P + P+T + K E +P E T +G +P + + + +P Sbjct: 673 APNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730 Query: 318 P--SPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPR----ASPHAT-PSTLHF 370 +PTT K+ + P+P T+ GTA T P T P+ +P T P+TL Sbjct: 731 KELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788 Query: 371 PTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNP 430 P ++P P P P T + P + P Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-----------------PTTPKETAPTTP 831 Query: 431 FLPTPMLPPPPPPPMARPVPLPVPDTKPPTT---STEGGAASPT----SPTYSTP--STS 481 P P P P P P+T PPTT ST PT SP STP S Sbjct: 832 KEPAPTTPKKPAPT--------TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883 Query: 482 PANRFVSVGPRDP 494 P + + P++P Sbjct: 884 PTPKALENSPKEP 896 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/216 (23%), Positives = 76/216 (35%), Gaps = 21/216 (9%) Query: 264 RSLPSTSSTSSTKRLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGMPSPTTL 323 +S P+T+ + KS +P E T + +P + + + P P+PTT Sbjct: 528 KSAPTTTKEPAPTTTKSAPT---TPKEPSPTTTKEPAPTTPKEPA---PTTPKKPAPTTP 581 Query: 324 KKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSP------IIQ 377 K+ + P+P+ T A T P T P+ + TP L PT+P + Sbjct: 582 KEPAPTTPKEPAPTTTKK--PAPTTPKEPAPTTPKETAPTTPKKLT-PTTPEKLAPTTPE 638 Query: 378 QPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPML 437 +P P P+E + P + A PN + P P P Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA------PNTPKEPAPTTPKEPAPTT 692 Query: 438 PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSP 473 P P P + P PTT E +P P Sbjct: 693 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728 Score = 40.8 bits (94), Expect = 0.003 Identities = 49/236 (20%), Positives = 88/236 (37%), Gaps = 19/236 (8%) Query: 249 LESSSYYSMSPGAMRRSLPSTSSTSSTK--RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQ 306 +E +S ++P + + P+ + ++TK L + ++ + +EP T + + Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372 Query: 307 SSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPS 366 S+ P P+PTT K + + P+P+ T + P T A P T S Sbjct: 373 SA---PTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPA-PTTTKS 427 Query: 367 TLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGK 426 PT+P ++P P P+E + P ++ + + Sbjct: 428 A---PTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-------TKEPA 475 Query: 427 VHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSP 482 P P P P P P + P PTT+ E +P P +T ++P Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531 Score = 40.4 bits (93), Expect = 0.004 Identities = 41/185 (22%), Positives = 62/185 (33%), Gaps = 16/185 (8%) Query: 315 PGMPSPTTLKK-----SEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLH 369 P P+PTT K+ E + + P+ T+ A T P T P+ P T + Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEP 514 Query: 370 FPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHN 429 PT+P P S P P T + + +P + + Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP----------SPTTTKEPAPTT 564 Query: 430 PFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSV 489 P P P P P P + P PTT+ + +P P +TP + + Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624 Query: 490 GPRDP 494 P P Sbjct: 625 TPTTP 629 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 49.3 bits (116), Expect = 8e-06 Identities = 52/169 (30%), Positives = 66/169 (39%), Gaps = 19/169 (11%) Query: 300 SPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRA 359 SP S G H P +P P + S SP PS+T T HH P G + Sbjct: 805 SPIMPPGSQGSHIHCPQLPQPALHQNSP-----SPVPSRTP------TPHHTPPSIGAQQ 853 Query: 360 SPHATPSTLHFPTSPIIQQPGPYFS--HPAIRYHPQETLKEFVQLVCPD--AGQQAGQVG 415 P AT PT P + PGP HP R P + Q V P A A Q Sbjct: 854 PP-ATTIPAPVPTPPAMP-PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911 Query: 416 FLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARP-VPLPVPDTKPPTTST 463 P P P+LPP P P+++P V + + PP+TS+ Sbjct: 912 -QQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959 Score = 35.8 bits (81), Expect = 0.095 Identities = 50/222 (22%), Positives = 81/222 (36%), Gaps = 24/222 (10%) Query: 291 EPFYTGQGRSPG-SGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPS--PSQTSSLGTAFT 347 +P T G P S + S +++ P + + L + + + P P QT L Sbjct: 679 QPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPL----- 733 Query: 348 QHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDA 407 QHH G A P A + + P +QQP P + + + P + Sbjct: 734 QHH-----GQLAQPGALNPPMGY--GPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSS 786 Query: 408 GQQAGQVGFLNPNGSSQGKVHNPFLPTPM------LPPPPPPPMARPVPLPVPDTKPPTT 461 GQ ++ SS V++P +P P P P + + P PVP P Sbjct: 787 GQAPVSQAQMS---SSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPH 843 Query: 462 STEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQT 503 T + P + P+ P + GP+ + P+QT Sbjct: 844 HTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQT 885 Score = 32.3 bits (72), Expect = 1.0 Identities = 54/258 (20%), Positives = 85/258 (32%), Gaps = 13/258 (5%) Query: 235 PIAAGTGPNFSLSDLESSSYYSM-SPGAMRRSLPSTSSTSSTKRLKSVEDEMDSPGEEPF 293 P++ GPN +S + P +R S+P+ T + + S + P Sbjct: 666 PVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPI 725 Query: 294 YTGQGRSPGSGSQSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPV 353 Q Q + + P M +++ G P +Q S G T Sbjct: 726 VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQ-TQFPSQGMNVTNIPLAP 784 Query: 354 ITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEF----VQLVCPDAGQ 409 +G A S+ P + I PG SH PQ L + V P Sbjct: 785 SSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHH 844 Query: 410 QAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTS--TEGGA 467 +G P ++ + P P +PP P P P P PPTT + Sbjct: 845 TPPSIGAQQPPATT---IPAPVPTPPAMPPGPQSQALHPPPRQTP--TPPTTQLPQQVQP 899 Query: 468 ASPTSPTYSTPSTSPANR 485 + P +P+ P P ++ Sbjct: 900 SLPAAPSADQPQQQPRSQ 917 Score = 30.0 bits (66), Expect = 5.2 Identities = 27/100 (27%), Positives = 32/100 (32%), Gaps = 6/100 (6%) Query: 409 QQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVPLPVPDTKPPTTSTEGGAA 468 Q+ G VG G P PT P P P P P P P AA Sbjct: 1836 QRTGVVG--QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAA 1893 Query: 469 SPTSPTYS----TPSTSPANRFVSVGPRDPSFVNIPQQTQ 504 P S + TP T P + P+ V + Q Q Sbjct: 1894 GPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQ 1933 Score = 29.6 bits (65), Expect = 6.8 Identities = 46/205 (22%), Positives = 68/205 (33%), Gaps = 23/205 (11%) Query: 306 QSSGWHEVEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVITGPRASPHATP 365 Q +G + G+PSPT + +G P+ QT P + P TP Sbjct: 1836 QRTGVVGQQQGLPSPTPATPTTPTG-QQPTTPQTPQ---------------PTSQPQPTP 1879 Query: 366 STLHFPTSPIIQQPGPYFSHPAIRYHPQETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQG 425 P P Q GP A T + Q P A ++ + Sbjct: 1880 PNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ 1939 Query: 426 K--VHNPFLPTPML-PPPPPPPMARPVPLPVPDTKPPTTSTEGGAASPTSPTYSTPSTS- 481 + H P+ PP PMA P P T+ P+ E G PT P + Sbjct: 1940 RQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPG-MGPTGMQQQPPWSQG 1998 Query: 482 --PANRFVSVGPRDPSFVNIPQQTQ 504 P + + G P+ +++ Q Q Sbjct: 1999 GLPQPQQLQSGMPRPAMMSVAQHGQ 2023 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.131 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,542,940 Number of Sequences: 37866 Number of extensions: 1595959 Number of successful extensions: 26042 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 524 Number of HSP's successfully gapped in prelim test: 864 Number of HSP's that attempted gapping in prelim test: 11685 Number of HSP's gapped (non-prelim): 7610 length of query: 509 length of database: 18,247,518 effective HSP length: 107 effective length of query: 402 effective length of database: 14,195,856 effective search space: 5706734112 effective search space used: 5706734112 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.