BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19743850 decorin isoform c precursor [Homo sapiens] (212 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|19743850 decorin isoform c precursor [Homo sapiens] 437 e-123 gi|19743848 decorin isoform b precursor [Homo sapiens] 418 e-117 gi|19743846 decorin isoform a preproprotein [Homo sapiens] 291 3e-79 gi|4503271 decorin isoform a preproprotein [Homo sapiens] 291 3e-79 gi|19743852 decorin isoform d precursor [Homo sapiens] 261 2e-70 gi|41350214 asporin [Homo sapiens] 176 2e-44 gi|4502403 biglycan preproprotein [Homo sapiens] 175 2e-44 gi|19743854 decorin isoform e precursor [Homo sapiens] 155 3e-38 gi|188528675 slit homolog 1 [Homo sapiens] 74 9e-14 gi|11321571 slit homolog 3 [Homo sapiens] 74 1e-13 gi|4759146 slit homolog 2 [Homo sapiens] 68 5e-12 gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 60 1e-09 gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 60 2e-09 gi|71040111 fibromodulin precursor [Homo sapiens] 60 2e-09 gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] 59 3e-09 gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] 59 3e-09 gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 57 9e-09 gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 57 9e-09 gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 57 1e-08 gi|13375646 leucine rich repeat and fibronectin type III domain ... 57 2e-08 gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom... 56 3e-08 gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 56 3e-08 gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 56 3e-08 gi|4758460 glycoprotein V (platelet) [Homo sapiens] 55 3e-08 gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 55 3e-08 gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 55 3e-08 gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 55 3e-08 gi|149773484 leucine rich repeat and fibronectin type III domain... 55 4e-08 gi|31542244 leucine rich repeat and fibronectin type III domain ... 55 4e-08 gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 55 6e-08 >gi|19743850 decorin isoform c precursor [Homo sapiens] Length = 212 Score = 437 bits (1123), Expect = e-123 Identities = 212/212 (100%), Positives = 212/212 (100%) Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 Query: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN Sbjct: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120 Query: 121 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 180 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV Sbjct: 121 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 180 Query: 181 SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 212 SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK Sbjct: 181 SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 212 >gi|19743848 decorin isoform b precursor [Homo sapiens] Length = 250 Score = 418 bits (1074), Expect = e-117 Identities = 212/250 (84%), Positives = 212/250 (84%), Gaps = 38/250 (15%) Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 Query: 61 HLRVVQCSDL--------------------------------------GLPPSLTELHLD 82 HLRVVQCSDL GLPPSLTELHLD Sbjct: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD 120 Query: 83 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 142 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA Sbjct: 121 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180 Query: 143 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 202 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV Sbjct: 181 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 240 Query: 203 RSAIQLGNYK 212 RSAIQLGNYK Sbjct: 241 RSAIQLGNYK 250 >gi|19743846 decorin isoform a preproprotein [Homo sapiens] Length = 359 Score = 291 bits (745), Expect = 3e-79 Identities = 142/142 (100%), Positives = 142/142 (100%) Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 130 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD Sbjct: 218 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 277 Query: 131 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 190 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW Sbjct: 278 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 337 Query: 191 EIQPSTFRCVYVRSAIQLGNYK 212 EIQPSTFRCVYVRSAIQLGNYK Sbjct: 338 EIQPSTFRCVYVRSAIQLGNYK 359 Score = 191 bits (486), Expect = 3e-49 Identities = 112/223 (50%), Positives = 136/223 (60%), Gaps = 27/223 (12%) Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 Query: 61 HLRVVQCSDLG-------LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 113 HLRVVQCSDLG LPP T L L NKI+ + K L NL L L N IS V Sbjct: 61 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 120 Query: 114 DNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK 173 G+ L L+L N+L +P + K +Q + H N I+ V + Sbjct: 121 SPGAFTPLVKLERLYLSKNQLKELPEKMP--KTLQELRAHENEITKV------------R 166 Query: 174 KASYSG------VSLFSNPVQYWEIQPSTFRCVYVRSAIQLGN 210 K +++G + L +NP++ I+ F+ + S I++ + Sbjct: 167 KVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIAD 209 Score = 41.2 bits (95), Expect = 7e-04 Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHL 129 +P +L EL N+I++V + GLN + + L N + S ++NG+ L + + Sbjct: 148 MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRI 207 Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 163 + +T +P GL + ++L N IS V ++ Sbjct: 208 ADTNITSIPQGLPPS--LTELHLDGNKISRVDAA 239 >gi|4503271 decorin isoform a preproprotein [Homo sapiens] Length = 359 Score = 291 bits (745), Expect = 3e-79 Identities = 142/142 (100%), Positives = 142/142 (100%) Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 130 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD Sbjct: 218 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 277 Query: 131 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 190 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW Sbjct: 278 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 337 Query: 191 EIQPSTFRCVYVRSAIQLGNYK 212 EIQPSTFRCVYVRSAIQLGNYK Sbjct: 338 EIQPSTFRCVYVRSAIQLGNYK 359 Score = 191 bits (486), Expect = 3e-49 Identities = 112/223 (50%), Positives = 136/223 (60%), Gaps = 27/223 (12%) Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 Query: 61 HLRVVQCSDLG-------LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 113 HLRVVQCSDLG LPP T L L NKI+ + K L NL L L N IS V Sbjct: 61 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 120 Query: 114 DNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK 173 G+ L L+L N+L +P + K +Q + H N I+ V + Sbjct: 121 SPGAFTPLVKLERLYLSKNQLKELPEKMP--KTLQELRAHENEITKV------------R 166 Query: 174 KASYSG------VSLFSNPVQYWEIQPSTFRCVYVRSAIQLGN 210 K +++G + L +NP++ I+ F+ + S I++ + Sbjct: 167 KVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIAD 209 Score = 41.2 bits (95), Expect = 7e-04 Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHL 129 +P +L EL N+I++V + GLN + + L N + S ++NG+ L + + Sbjct: 148 MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRI 207 Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 163 + +T +P GL + ++L N IS V ++ Sbjct: 208 ADTNITSIPQGLPPS--LTELHLDGNKISRVDAA 239 >gi|19743852 decorin isoform d precursor [Homo sapiens] Length = 172 Score = 261 bits (668), Expect = 2e-70 Identities = 141/219 (64%), Positives = 145/219 (66%), Gaps = 54/219 (24%) Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 Query: 61 HLRVVQCSDLG-------LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 113 HLRVVQCSDLG LPP T L L NKI+ + K L NL + L N+IS V Sbjct: 61 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHVVYLHNNNISVV 120 Query: 114 DNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK 173 GSSDFCPPGHNTK Sbjct: 121 -----------------------------------------------GSSDFCPPGHNTK 133 Query: 174 KASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 212 KASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK Sbjct: 134 KASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 172 >gi|41350214 asporin [Homo sapiens] Length = 380 Score = 176 bits (445), Expect = 2e-44 Identities = 81/155 (52%), Positives = 112/155 (72%), Gaps = 4/155 (2%) Query: 61 HLRVVQCS----DLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 116 H+R+ + GLPP+L ELHLD NKIS V+ K L +LGL N I+ ++NG Sbjct: 224 HIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENG 283 Query: 117 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKAS 176 SLAN P +RE+HL+NNKL ++P GL E KY+Q+++LH+N+I+ VG +DFCP KK+ Sbjct: 284 SLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSL 343 Query: 177 YSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 211 YS +SLF+NPV+YWE+QP+TFRCV R ++QLGN+ Sbjct: 344 YSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNF 378 Score = 79.7 bits (195), Expect = 2e-15 Identities = 70/231 (30%), Positives = 99/231 (42%), Gaps = 38/231 (16%) Query: 1 MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45 MK ++LL LA S A PF L + ML+D + DD D Sbjct: 1 MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59 Query: 46 -------FEPSLGPVCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDA 91 F L P+CPF CQC+ RVV CSDLGL P L L NKI + Sbjct: 60 REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119 Query: 92 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 151 KGL +L L L+ N ++ + + T LR L+L +N+L+ +P L K + + Sbjct: 120 NDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP--KSLAELR 177 Query: 152 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 202 +H N + + F G N + + +NP+ I+P F V V Sbjct: 178 IHENKVKKIQKDTF--KGMNALHV----LEMSANPLDNNGIEPGAFEGVTV 222 >gi|4502403 biglycan preproprotein [Homo sapiens] Length = 368 Score = 175 bits (444), Expect = 2e-44 Identities = 84/141 (59%), Positives = 103/141 (73%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131 LP +L ELHLD NKI ++ L + L +LGL N I ++NGSL+ P LRELHLDN Sbjct: 227 LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDN 286 Query: 132 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWE 191 NKL RVP GL + K +QVVYLH+NNI+ VG +DFCP G K+A Y+G+SLF+NPV YWE Sbjct: 287 NKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWE 346 Query: 192 IQPSTFRCVYVRSAIQLGNYK 212 +QP+TFRCV R AIQ GNYK Sbjct: 347 VQPATFRCVTDRLAIQFGNYK 367 Score = 95.9 bits (237), Expect = 2e-20 Identities = 69/207 (33%), Positives = 98/207 (47%), Gaps = 24/207 (11%) Query: 7 LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57 L+ L +S A PF+QRG +DF L+D EASG V D P+ +CPF Sbjct: 7 LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66 Query: 58 CQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI 110 C CHLRVVQCSDLGL P T L L N IS + KGL +L L L N I Sbjct: 67 CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126 Query: 111 SAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGH 170 S + + + L++L++ N L +P L + + +H+N I V P G Sbjct: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSS--LVELRIHDNRIRKV------PKGV 178 Query: 171 NTKKASYSGVSLFSNPVQYWEIQPSTF 197 + + + + + NP++ +P F Sbjct: 179 FSGLRNMNCIEMGGNPLENSGFEPGAF 205 >gi|19743854 decorin isoform e precursor [Homo sapiens] Length = 75 Score = 155 bits (391), Expect = 3e-38 Identities = 73/75 (97%), Positives = 73/75 (97%) Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60 Query: 61 HLRVVQCSDLGLPPS 75 HLRVVQCSDLG PS Sbjct: 61 HLRVVQCSDLGCLPS 75 >gi|188528675 slit homolog 1 [Homo sapiens] Length = 1534 Score = 73.9 bits (180), Expect = 9e-14 Identities = 51/165 (30%), Positives = 81/165 (49%), Gaps = 17/165 (10%) Query: 53 VCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASL-KGLNNLAKLG 104 VCP +C+C VV+CS L L P S EL L+ N+IS ++A + K L +L K+ Sbjct: 512 VCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKIN 571 Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSS 163 LS N +S +++G+ + ELHL N+L + G+ ++ + L NN IS + + Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631 Query: 164 DFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQL 208 F T + +SL+ N Q + P F + S + L Sbjct: 632 SF------TGLRNVRLLSLYDN--QITTVSPGAFDTLQSLSTLNL 668 Score = 52.0 bits (123), Expect = 4e-07 Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106 CP C C V C GL P + L L+GN I+R+ GL L L L Sbjct: 34 CPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLM 93 Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVP 138 N I AV+ G+ + L L L+ N+L +P Sbjct: 94 ENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125 Score = 51.6 bits (122), Expect = 5e-07 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 14/143 (9%) Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106 CP C C +V C GL P ++TE+ L+ N I + + L ++ LS Sbjct: 282 CPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341 Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNISVVGSSDF 165 N I+ + + L L L NK+T +P G+ Y +Q++ L+ N I+ + F Sbjct: 342 NNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 401 Query: 166 CPPGHNTKKASYSGVSLFSNPVQ 188 + S +SL+ N +Q Sbjct: 402 ------QDLQNLSLLSLYDNKIQ 418 Score = 46.2 bits (108), Expect = 2e-05 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 30/120 (25%) Query: 52 PVCPFRCQCHLRVVQCSDL-------GLPPSLTELHLDGN-------------------- 84 P CP C C VV+CS+ G+P ++TEL+LDGN Sbjct: 732 PQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791 Query: 85 ---KISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL 141 KIS + +S ++ L L LS+N++ + + LR L L N ++ + G+ Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851 Score = 44.7 bits (104), Expect = 6e-05 Identities = 21/43 (48%), Positives = 30/43 (69%) Query: 123 HLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165 ++ EL+LD N+ T VPG L+ KY+Q+V L NN IS + +S F Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSF 804 Score = 36.6 bits (83), Expect = 0.016 Identities = 20/59 (33%), Positives = 31/59 (52%) Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 L L LD N+IS ++ + + L L L L+ N+I+ + S + P LR L +N L Sbjct: 159 LKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217 Score = 31.6 bits (70), Expect = 0.52 Identities = 18/58 (31%), Positives = 31/58 (53%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNN 132 +L L L+ NKI+ + + + L NL+ L L N I ++ G+ + ++ LHL N Sbjct: 382 TLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439 >gi|11321571 slit homolog 3 [Homo sapiens] Length = 1523 Score = 73.6 bits (179), Expect = 1e-13 Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 21/149 (14%) Query: 50 LGPVCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAK 102 L P CP +C C VV+CS+ GL P +TEL+L+GN ++ V L L +L Sbjct: 721 LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPR-ELSALRHLTL 779 Query: 103 LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHKYIQVVYLHNNNIS 158 + LS NSIS + N + +N HL L L N+L +P GL + ++V+ LH N+IS Sbjct: 780 IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGL---RSLRVLTLHGNDIS 836 Query: 159 VVGSSDFCPPGHNTKKASYSGVSLFSNPV 187 V P G S S ++L +NP+ Sbjct: 837 SV------PEGSFNDLTSLSHLALGTNPL 859 Score = 61.2 bits (147), Expect = 6e-10 Identities = 48/161 (29%), Positives = 73/161 (45%), Gaps = 27/161 (16%) Query: 53 VCPFRCQCHLRVVQCSD-------LGLPPSLTELHLDGNKISRVDAASL-KGLNNLAKLG 104 VCP +C+C +V CS+ LP +T+L L+ N++S ++A + K L NL K+ Sbjct: 504 VCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKIN 563 Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSS 163 LS N I V G+ ++EL L N+L V G + ++ + L +N I V + Sbjct: 564 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 623 Query: 164 DFC------------------PPGHNTKKASYSGVSLFSNP 186 F PG T S S ++L SNP Sbjct: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664 Score = 58.5 bits (140), Expect = 4e-09 Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 7/92 (7%) Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106 CP +C C V C LGL P + L LD N I+R+ GL NL L L Sbjct: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93 Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVP 138 N +S ++ G+ + L L L+ NKL +P Sbjct: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125 Score = 43.9 bits (102), Expect = 1e-04 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P LT L L N+I + + +G+ ++ L L N IS +++G+ L L L+NN Sbjct: 133 PKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNN 192 Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNI 157 ++R+ H I+ + LH+N++ Sbjct: 193 ISRILVTSFNHMPKIRTLRLHSNHL 217 Score = 38.9 bits (89), Expect = 0.003 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 SLT L L GNKI+ + GL +L L L+ N I+ + + + +L L L +NKL Sbjct: 356 SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415 Query: 135 TRVPGGL-AEHKYIQVVYLHNN 155 + GL A + IQ ++L N Sbjct: 416 QTISKGLFAPLQSIQTLHLAQN 437 Score = 36.2 bits (82), Expect = 0.021 Identities = 32/146 (21%), Positives = 57/146 (39%), Gaps = 32/146 (21%) Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGN--------------KISRVDAA 92 CP C C +V C GL P + E+ L+ N K+ R+D + Sbjct: 280 CPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDIS 339 Query: 93 ----------SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGL 141 + +GL +L L L N I+ + G L+ L L+ NK+ + Sbjct: 340 KNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTF 399 Query: 142 AEHKYIQVVYLHNNNISVVGSSDFCP 167 + + + ++ L++N + + F P Sbjct: 400 QDLQNLNLLSLYDNKLQTISKGLFAP 425 >gi|4759146 slit homolog 2 [Homo sapiens] Length = 1529 Score = 68.2 bits (165), Expect = 5e-12 Identities = 52/156 (33%), Positives = 80/156 (51%), Gaps = 17/156 (10%) Query: 42 DDRDFEPSLGPV--CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAA 92 DD + + S P+ CP C C VV+CS+ GL P +TEL+LDGN+ + V Sbjct: 713 DDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPK- 771 Query: 93 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVY 151 L +L + LS N IS + N S +N L L L N+L +P + K ++++ Sbjct: 772 ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLS 831 Query: 152 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 187 LH N+ISVV P G ++ S +++ +NP+ Sbjct: 832 LHGNDISVV------PEGAFNDLSALSHLAIGANPL 861 Score = 52.8 bits (125), Expect = 2e-07 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106 CP +C C V C L L P + L L+GN I+R+ GL +L L L Sbjct: 28 CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLM 87 Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVP 138 N IS ++ G+ + L L L+ N L P Sbjct: 88 ENKISTIERGAFQDLKELERLRLNRNHLQLFP 119 Score = 51.6 bits (122), Expect = 5e-07 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 8/113 (7%) Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106 CP C C +V C GL P ++TE+ L+ N I + + L ++ LS Sbjct: 273 CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLS 332 Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNIS 158 N IS + + L L L NK+T +P L E + +Q++ L+ N I+ Sbjct: 333 NNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKIN 385 Score = 42.7 bits (99), Expect = 2e-04 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT 135 L L L N+I + + +G ++ L L +N IS +++G+ L L L+NN +T Sbjct: 129 LYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNIT 188 Query: 136 RVPGGLAEH-KYIQVVYLHNNNI 157 R+ H ++ LH+NN+ Sbjct: 189 RLSVASFNHMPKLRTFRLHSNNL 211 Score = 38.9 bits (89), Expect = 0.003 Identities = 39/189 (20%), Positives = 74/189 (39%), Gaps = 51/189 (26%) Query: 40 VPDDRDFEPSLGP------VCPFRCQCHLRVVQCSDLGLP-------------------- 73 +P D+ L CP +C+C V CS+ L Sbjct: 486 IPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEF 545 Query: 74 ------------PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121 P L +++ NKI+ ++ + +G + + ++ L+ N + V + Sbjct: 546 TVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGL 605 Query: 122 PHLRELHLDNNKLTRVPG----GLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASY 177 L+ L L +N++T V GL+ ++++ L++N I+ V PG S Sbjct: 606 ESLKTLMLRSNRITCVGNDSFIGLSS---VRLLSLYDNQITTVA------PGAFDTLHSL 656 Query: 178 SGVSLFSNP 186 S ++L +NP Sbjct: 657 STLNLLANP 665 Score = 35.0 bits (79), Expect = 0.047 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 SL L L GNKI+ + + +GL +L L L+ N I+ + + + +L L L +NKL Sbjct: 349 SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKL 408 Query: 135 -TRVPGGLAEHKYIQVVYLHNN 155 T G + + IQ ++L N Sbjct: 409 QTIAKGTFSPLRAIQTMHLAQN 430 >gi|76880480 hypothetical protein LOC9865 [Homo sapiens] Length = 811 Score = 60.1 bits (144), Expect = 1e-09 Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 13/131 (9%) Query: 48 PSLGPVCPFRCQCH-----------LRVV-QCSDLGLPPSLTELHLDGNKISRVDAASLK 95 P PVCP RC C LRVV + S L P + L GN I+ + A Sbjct: 21 PLAEPVCPERCDCQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFH 80 Query: 96 GLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHN 154 L L +L L +N I ++ + L EL+L NN L + PG LA + ++++Y + Sbjct: 81 RLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANG 140 Query: 155 NNISVVGSSDF 165 N IS + F Sbjct: 141 NEISRLSRGSF 151 Score = 48.9 bits (115), Expect = 3e-06 Identities = 26/67 (38%), Positives = 42/67 (62%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +L EL L+GN++S++ A L+ L++L L LS N +SA+ + + LREL L NN L Sbjct: 278 ALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 337 Query: 135 TRVPGGL 141 + + G + Sbjct: 338 SALSGDI 344 Score = 43.5 bits (101), Expect = 1e-04 Identities = 21/56 (37%), Positives = 36/56 (64%) Query: 79 LHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 L+ +GN+ISR+ S +GL +L KL L N++ A+ + A +L LHL++N++ Sbjct: 136 LYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRI 191 Score = 35.8 bits (81), Expect = 0.028 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 SL+ L L N + + + L L L L N ++ + + LREL L+ N+L Sbjct: 230 SLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRL 289 Query: 135 TRVPGGLAEHKY-IQVVYLHNNNISVVGSSDFCPPG-------HNTKKASYSGVSLFSNP 186 +++P L E + ++ + L N +S + + F G N ++ SG ++P Sbjct: 290 SQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASP 349 Query: 187 VQY 189 Y Sbjct: 350 ALY 352 Score = 27.7 bits (60), Expect = 7.5 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 11/122 (9%) Query: 79 LHLDGNKI--SRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTR 136 L+L N++ S AA+ L +L+ L LS N++ + + P L L L N+LT Sbjct: 208 LNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTH 267 Query: 137 V-PGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPS 195 + P + ++ + L N +S + ++ P H+ + SG L + + P+ Sbjct: 268 LAPEAFWGLEALRELRLEGNRLSQLPTA-LLEPLHSLEALDLSGNELSA-------LHPA 319 Query: 196 TF 197 TF Sbjct: 320 TF 321 >gi|229089140 leucine rich repeat containing 24 [Homo sapiens] Length = 513 Score = 59.7 bits (143), Expect = 2e-09 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 8/113 (7%) Query: 54 CPFRCQCHLRVVQCS-------DLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106 CP C+C+ V+C LG+PP L L N I+R++ +L L L +L L Sbjct: 23 CPAACRCYSATVECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLH 82 Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNIS 158 NS+ A++ G+ P L EL L +N+L + G ++V+YL N ++ Sbjct: 83 NNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLA 135 Score = 39.3 bits (90), Expect = 0.002 Identities = 22/59 (37%), Positives = 31/59 (52%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNN 132 P L ELHL N I ++ +L GL++LA L LS N + + +L L+ L L N Sbjct: 146 PRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTEN 204 Score = 38.1 bits (87), Expect = 0.006 Identities = 21/73 (28%), Positives = 37/73 (50%) Query: 62 LRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121 LR ++ P L EL L N++ + + + GL L L L+ N ++ + + + + Sbjct: 86 LRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHL 145 Query: 122 PHLRELHLDNNKL 134 P L+ELHL N + Sbjct: 146 PRLQELHLQENSI 158 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/59 (33%), Positives = 32/59 (54%) Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 L L+L GN+++R+ + L L +L L NSI +++ +LA L L L N+L Sbjct: 124 LRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQL 182 Score = 30.0 bits (66), Expect = 1.5 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 122 PHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNISVVGSSDF 165 P + L L +N + R+ PG LA ++ +YLHNN++ + + F Sbjct: 50 PGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAF 94 >gi|71040111 fibromodulin precursor [Homo sapiens] Length = 376 Score = 59.7 bits (143), Expect = 2e-09 Identities = 40/94 (42%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131 LP SL ELHLD N+ISRV +L+GL NL L L N I V S+ L L L Sbjct: 174 LPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV-GSSMRGLRSLILLDLSY 232 Query: 132 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165 N L +VP GL ++ +Y+ +NN+ V S F Sbjct: 233 NHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYF 264 Score = 46.2 bits (108), Expect = 2e-05 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 11/109 (10%) Query: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120 HLR V GLP +L +L+++ N + V + +G L + LS NS++ +NG +N Sbjct: 234 HLRKVPD---GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLT--NNGLASN 288 Query: 121 T---PHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFC 166 T L EL L N+L ++P + ++ +YL N I+ S FC Sbjct: 289 TFNSSSLLELDLSYNQLQKIP---PVNTNLENLYLQGNRINEFSISSFC 334 Score = 44.7 bits (104), Expect = 6e-05 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 21/134 (15%) Query: 38 PEVPDDRDFEPSLGPVCPFRCQCHLR---VVQCSDLGL------PPSLTELHLDGNKISR 88 P PD RD CP C C + C + L P + ++ N+I+ Sbjct: 68 PSPPDPRD--------CPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITS 119 Query: 89 VDAASLKGLNNLAKLGLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY 146 + L + L N I++ V + HL L+LD+N LTR+PG L + Sbjct: 120 IQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLP--RS 177 Query: 147 IQVVYLHNNNISVV 160 ++ ++L +N IS V Sbjct: 178 LRELHLDHNQISRV 191 >gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] Length = 522 Score = 58.9 bits (141), Expect = 3e-09 Identities = 44/130 (33%), Positives = 66/130 (50%), Gaps = 15/130 (11%) Query: 48 PSLGPVCPFRCQCHLRVVQCSDLGL---PPSL----TELHLDGNKISRVDA----ASLKG 96 P VCP C C +V C++ L P +L L L N+I +D+ S Sbjct: 35 PGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAK 94 Query: 97 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNN 155 LN L L N+I+++ GS + TP+L+ L L +NKL V + E K ++V+ L+NN Sbjct: 95 LNTLI---LRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNN 151 Query: 156 NISVVGSSDF 165 +IS + S F Sbjct: 152 HISYLDPSAF 161 Score = 35.4 bits (80), Expect = 0.036 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 7/85 (8%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P+L L L NK+ V A + L L L L N IS +D + L++L+L N Sbjct: 117 PNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNF 176 Query: 134 LTRVPGG-------LAEHKYIQVVY 151 LT+ P LAE ++ V Y Sbjct: 177 LTQFPMDLYVGRFKLAELMFLDVSY 201 >gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] Length = 522 Score = 58.9 bits (141), Expect = 3e-09 Identities = 44/130 (33%), Positives = 66/130 (50%), Gaps = 15/130 (11%) Query: 48 PSLGPVCPFRCQCHLRVVQCSDLGL---PPSL----TELHLDGNKISRVDA----ASLKG 96 P VCP C C +V C++ L P +L L L N+I +D+ S Sbjct: 35 PGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAK 94 Query: 97 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNN 155 LN L L N+I+++ GS + TP+L+ L L +NKL V + E K ++V+ L+NN Sbjct: 95 LNTLI---LRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNN 151 Query: 156 NISVVGSSDF 165 +IS + S F Sbjct: 152 HISYLDPSAF 161 Score = 35.4 bits (80), Expect = 0.036 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 7/85 (8%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P+L L L NK+ V A + L L L L N IS +D + L++L+L N Sbjct: 117 PNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNF 176 Query: 134 LTRVPGG-------LAEHKYIQVVY 151 LT+ P LAE ++ V Y Sbjct: 177 LTQFPMDLYVGRFKLAELMFLDVSY 201 >gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] Length = 713 Score = 57.4 bits (137), Expect = 9e-09 Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 27/128 (21%) Query: 54 CPFRCQCHLR-------------VVQCSDLGL---PPSLTE----LHLDGNKISRVDAAS 93 CP +C C +R V C+DL L PP+L L L N I RVD + Sbjct: 29 CPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSE 88 Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHKYIQV 149 L L NL +L LS NS S + P L LHL+ N+LTR+ GLA +Q Sbjct: 89 LGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS---LQE 145 Query: 150 VYLHNNNI 157 +YL++N + Sbjct: 146 LYLNHNQL 153 Score = 41.2 bits (95), Expect = 7e-04 Identities = 21/63 (33%), Positives = 37/63 (58%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 SL EL+L+ N++ R+ + GL+NL +L L+ N + A+D+ P+L L + NK+ Sbjct: 142 SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKV 201 Query: 135 TRV 137 + Sbjct: 202 DAI 204 Score = 39.3 bits (90), Expect = 0.002 Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 1/105 (0%) Query: 62 LRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121 LR + + P+L L + GNK+ + + + L NL L L+ ++ + + +L Sbjct: 177 LRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGL 236 Query: 122 PHLRELHLDNNKLTRVP-GGLAEHKYIQVVYLHNNNISVVGSSDF 165 L L +N+L RVP L + ++ + L+ N + VG DF Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDF 281 Score = 36.6 bits (83), Expect = 0.016 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 3/90 (3%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS-FNSISAVDNGSLANTPHLRELHLDNN 132 P L L L+ N + RV + +L +LGL+ + ++D +L N P L +L + NN Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNN 320 Query: 133 -KLTRV-PGGLAEHKYIQVVYLHNNNISVV 160 +L+ + P ++ + L+NN +S + Sbjct: 321 PRLSFIHPRAFHHLPQMETLMLNNNALSAL 350 Score = 35.8 bits (81), Expect = 0.028 Identities = 21/57 (36%), Positives = 31/57 (54%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131 SL L N+++RV +L+ + L L L+ N + V G AN HL+EL L+N Sbjct: 238 SLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294 >gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] Length = 713 Score = 57.4 bits (137), Expect = 9e-09 Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 27/128 (21%) Query: 54 CPFRCQCHLR-------------VVQCSDLGL---PPSLTE----LHLDGNKISRVDAAS 93 CP +C C +R V C+DL L PP+L L L N I RVD + Sbjct: 29 CPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSE 88 Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHKYIQV 149 L L NL +L LS NS S + P L LHL+ N+LTR+ GLA +Q Sbjct: 89 LGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS---LQE 145 Query: 150 VYLHNNNI 157 +YL++N + Sbjct: 146 LYLNHNQL 153 Score = 41.2 bits (95), Expect = 7e-04 Identities = 21/63 (33%), Positives = 37/63 (58%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 SL EL+L+ N++ R+ + GL+NL +L L+ N + A+D+ P+L L + NK+ Sbjct: 142 SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKV 201 Query: 135 TRV 137 + Sbjct: 202 DAI 204 Score = 39.3 bits (90), Expect = 0.002 Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 1/105 (0%) Query: 62 LRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121 LR + + P+L L + GNK+ + + + L NL L L+ ++ + + +L Sbjct: 177 LRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGL 236 Query: 122 PHLRELHLDNNKLTRVP-GGLAEHKYIQVVYLHNNNISVVGSSDF 165 L L +N+L RVP L + ++ + L+ N + VG DF Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDF 281 Score = 36.6 bits (83), Expect = 0.016 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 3/90 (3%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS-FNSISAVDNGSLANTPHLRELHLDNN 132 P L L L+ N + RV + +L +LGL+ + ++D +L N P L +L + NN Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNN 320 Query: 133 -KLTRV-PGGLAEHKYIQVVYLHNNNISVV 160 +L+ + P ++ + L+NN +S + Sbjct: 321 PRLSFIHPRAFHHLPQMETLMLNNNALSAL 350 Score = 35.8 bits (81), Expect = 0.028 Identities = 21/57 (36%), Positives = 31/57 (54%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131 SL L N+++RV +L+ + L L L+ N + V G AN HL+EL L+N Sbjct: 238 SLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294 >gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] Length = 699 Score = 57.0 bits (136), Expect = 1e-08 Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 5/141 (3%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLN-NLAKLGLSFNSIS--AVDNGSLANTPH-LREL 127 LP SL L L GN+I R+ + L L LSFN ++ +D S H LREL Sbjct: 554 LPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLREL 613 Query: 128 HLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 187 LD+N L +P G+ E K + + L+NN I + + C ++ + L +N + Sbjct: 614 FLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEIC-NAEEDDDSNLEHLHLENNYI 672 Query: 188 QYWEIQPSTFRCVYVRSAIQL 208 + EI TF C+ S+I L Sbjct: 673 KIREIPSYTFSCIRSYSSIVL 693 Score = 45.8 bits (107), Expect = 3e-05 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 11/115 (9%) Query: 55 PFRCQCHLRVVQCSDLGLP-------PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSF 107 P C R + C + L P +T L L GN I+ + + GL NL +L LS Sbjct: 317 PSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSK 376 Query: 108 NSISAVDNGSLA--NTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVV 160 N+I++ G A L L++D N L ++P L ++ + ++ NN+ + Sbjct: 377 NNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLP--STLEELKVNENNLQAI 429 Score = 35.4 bits (80), Expect = 0.036 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLA--NTPHLRELH 128 GLP S+ EL+L+ N+I + + + L +N I LA N +L + Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESID 541 Query: 129 LDNNKLTRVPGGLAEHKYIQVVYLHN 154 L NKL VP L + + +V L N Sbjct: 542 LSYNKLYHVPSYLPK-SLLHLVLLGN 566 >gi|13375646 leucine rich repeat and fibronectin type III domain containing 3 [Homo sapiens] Length = 628 Score = 56.6 bits (135), Expect = 2e-08 Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 14/141 (9%) Query: 54 CPFRCQCHLRV----VQCSDLGL---PPSL----TELHLDGNKISRVDAASLKGLNNLAK 102 CP RC+C + V C GL PPSL EL L N I+ V L + L Sbjct: 28 CPRRCRCQTQSLPLSVLCPGAGLLFVPPSLDRRAAELRLADNFIASVRRRDLANMTGLLH 87 Query: 103 LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNISVV- 160 L LS N+I V G+ A+ LR LHLD N+LT + G L ++ + L NN ++ + Sbjct: 88 LSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALA 147 Query: 161 -GSSDFCPPGHNTKKASYSGV 180 G+ D C SY+ + Sbjct: 148 AGALDDCAETLEDLDLSYNNL 168 Score = 38.1 bits (87), Expect = 0.006 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 25/91 (27%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRE-------- 126 +L LHLDGN+++ + L+GL NL L LS N ++A+ G+L + E Sbjct: 108 ALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNN 167 Query: 127 -----------------LHLDNNKLTRVPGG 140 L LD+N L VP G Sbjct: 168 LEQLPWEALGRLGNVNTLGLDHNLLASVPAG 198 Score = 37.0 bits (84), Expect = 0.012 Identities = 19/64 (29%), Positives = 35/64 (54%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +L +L L N + ++ +L L N+ LGL N +++V G+ + L L + +N+L Sbjct: 157 TLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRL 216 Query: 135 TRVP 138 T +P Sbjct: 217 TTIP 220 >gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo sapiens] Length = 592 Score = 55.8 bits (133), Expect = 3e-08 Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 9/97 (9%) Query: 54 CPFRCQCHL--RVVQCSDL-------GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLG 104 CP RC+C + R V C+ G+P L L N+I ++ L L L +L Sbjct: 25 CPARCECTVQTRAVACTRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPALEELD 84 Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL 141 LS N+I+ V+ G+ AN P LR L L N+L +P G+ Sbjct: 85 LSENAIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGV 121 Score = 47.4 bits (111), Expect = 9e-06 Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +LT L + I+ V AA+L+ +L L LS N IS V GS + LRELHL L Sbjct: 247 NLTSLSVTHTNITAVPAAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALL 306 Query: 135 TRV-PGGLAEHKYIQVVYLHNNNISVVGSSDF 165 V P + I+++ L NN +S + S F Sbjct: 307 AVVEPQAFLGLRQIRLLNLSNNLLSTLEESTF 338 Score = 40.0 bits (92), Expect = 0.001 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 4/83 (4%) Query: 61 HLRVVQCSDLGLP--PSLTELHLDG-NKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 117 HL + D P L L +D + V A SL+GLN L L ++ +I+AV + Sbjct: 207 HLAIASLEDQNFRRLPGLLHLEIDNWPLLEEVAAGSLRGLN-LTSLSVTHTNITAVPAAA 265 Query: 118 LANTPHLRELHLDNNKLTRVPGG 140 L + HL L+L +N ++ VP G Sbjct: 266 LRHQAHLTCLNLSHNPISTVPRG 288 Score = 29.3 bits (64), Expect = 2.6 Identities = 19/64 (29%), Positives = 30/64 (46%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P L L L GN++ + L+NL L LS N + + + + + LR L + +N Sbjct: 102 PRLRVLRLRGNQLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLHSLRRLEVGDND 161 Query: 134 LTRV 137 L V Sbjct: 162 LVFV 165 >gi|38202222 fibronectin leucine rich transmembrane protein 3 precursor [Homo sapiens] Length = 649 Score = 55.8 bits (133), Expect = 3e-08 Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 32/139 (23%) Query: 54 CPFRCQCHLRVVQCSD-------LGLPPSLTELHLDGNKISRVDAAS-LKGL-------- 97 CP C+C + C+D G+P T L+L N+I+ S LK L Sbjct: 31 CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYL 90 Query: 98 ---------NNLAK----LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV---PGGL 141 NL K L L N+I + SL+ P+L ELHLD+N ++ V G Sbjct: 91 YHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAF 150 Query: 142 AEHKYIQVVYLHNNNISVV 160 + Y+++++L N++S + Sbjct: 151 RDSNYLRLLFLSRNHLSTI 169 Score = 50.8 bits (120), Expect = 8e-07 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV--DNGSLANTPHLRELHL 129 LP + ELHL N I + SL + L +L L NS+SAV + G+ ++ +LR L L Sbjct: 102 LPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFL 161 Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 162 N L+ +P GL + I+ + L +N IS + S Sbjct: 162 SRNHLSTIPWGLP--RTIEELRLDDNRISTISS 192 Score = 50.4 bits (119), Expect = 1e-06 Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 3/97 (3%) Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELH 128 GLP ++ EL LD N+IS + + SL+GL +L +L L N ++ + + N +L EL Sbjct: 172 GLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELS 231 Query: 129 LDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165 L N LT P L ++ +YL +N+I+ V + F Sbjct: 232 LVRNSLTAAPVNLPGTN-LRKLYLQDNHINRVPPNAF 267 >gi|7019383 fibronectin leucine rich transmembrane protein 3 precursor [Homo sapiens] Length = 649 Score = 55.8 bits (133), Expect = 3e-08 Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 32/139 (23%) Query: 54 CPFRCQCHLRVVQCSD-------LGLPPSLTELHLDGNKISRVDAAS-LKGL-------- 97 CP C+C + C+D G+P T L+L N+I+ S LK L Sbjct: 31 CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYL 90 Query: 98 ---------NNLAK----LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV---PGGL 141 NL K L L N+I + SL+ P+L ELHLD+N ++ V G Sbjct: 91 YHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAF 150 Query: 142 AEHKYIQVVYLHNNNISVV 160 + Y+++++L N++S + Sbjct: 151 RDSNYLRLLFLSRNHLSTI 169 Score = 50.8 bits (120), Expect = 8e-07 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV--DNGSLANTPHLRELHL 129 LP + ELHL N I + SL + L +L L NS+SAV + G+ ++ +LR L L Sbjct: 102 LPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFL 161 Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 162 N L+ +P GL + I+ + L +N IS + S Sbjct: 162 SRNHLSTIPWGLP--RTIEELRLDDNRISTISS 192 Score = 50.4 bits (119), Expect = 1e-06 Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 3/97 (3%) Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELH 128 GLP ++ EL LD N+IS + + SL+GL +L +L L N ++ + + N +L EL Sbjct: 172 GLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELS 231 Query: 129 LDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165 L N LT P L ++ +YL +N+I+ V + F Sbjct: 232 LVRNSLTAAPVNLPGTN-LRKLYLQDNHINRVPPNAF 267 >gi|4758460 glycoprotein V (platelet) [Homo sapiens] Length = 560 Score = 55.5 bits (132), Expect = 3e-08 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 10/122 (8%) Query: 54 CPFRCQCHLR---------VVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLG 104 CP C+C R V + S LGLP +LT + L G + + S G+ L +L Sbjct: 21 CPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQSQSFSGMTVLQRLM 80 Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHK-YIQVVYLHNNNISVVGSS 163 +S + ISAV G+ ++ L+ L L NK+T +PG L + ++ ++L +N + + + Sbjct: 81 ISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQN 140 Query: 164 DF 165 F Sbjct: 141 MF 142 Score = 38.5 bits (88), Expect = 0.004 Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 5/109 (4%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +LTEL N I + + L NL+ L LS N ++ + + ++ +L L L N L Sbjct: 219 ALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPL 278 Query: 135 TRVPGGL-AEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSL 182 +PG L E +Q ++L+ + + ++ F N + Y GV+L Sbjct: 279 AELPGVLFGEMGGLQELWLNRTQLRTLPAAAF----RNLSRLRYLGVTL 323 Score = 35.8 bits (81), Expect = 0.028 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT 135 L L L N ++ + L+GL L ++ L N + A+ N L + LD+N+L Sbjct: 341 LQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLE 400 Query: 136 RVPGGL--AEHKYIQVVYLHNN 155 +PG + A + +V+ HN+ Sbjct: 401 TLPGDVFGALPRLTEVLLGHNS 422 Score = 34.7 bits (78), Expect = 0.061 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 85 KISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH 144 ++S + + +GL L L L N ++A+ +G L LR++ L N+L +P L + Sbjct: 326 RLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRN 385 Query: 145 -KYIQVVYLHNNNISVVGSSDF 165 ++ V L +N + + F Sbjct: 386 LSSLESVQLDHNQLETLPGDVF 407 Score = 33.1 bits (74), Expect = 0.18 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 7/114 (6%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +L L L GN ++ + L L +L L N + ++D+G L + L EL N + Sbjct: 171 NLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHI 230 Query: 135 TRV-PGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 187 + PG + + L N+++ + S+ F HN + ++LF NP+ Sbjct: 231 RSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFL-HSHN-----LTLLTLFENPL 278 >gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] Length = 708 Score = 55.5 bits (132), Expect = 3e-08 Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 22/133 (16%) Query: 54 CPFRCQCHLR-------------VVQCSDLGL-------PPSLTELHLDGNKISRVDAAS 93 CP C C +R V C+DLGL P + L L N I++++ ++ Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88 Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGG-LAEHKYIQVVYL 152 +N L L LS N++S+V N ++ P L ++L+ NKLT +P L+E +Q +Y+ Sbjct: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147 Query: 153 HNNNISVVGSSDF 165 ++N +S + F Sbjct: 148 NHNLLSTISPGAF 160 Score = 42.0 bits (97), Expect = 4e-04 Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P L ++L+ NK++ + L L+NL +L ++ N +S + G+ +L LHL++N+ Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175 Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNP 186 L + + ++++ + N I + +F P N + +G++L P Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNF-KPLINLRSLVIAGINLTEIP 228 Score = 33.9 bits (76), Expect = 0.10 Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P+L L + N I R+ + K L NL L ++ +++ + + +L +L + +N+ Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247 Query: 134 LTRVPGGLAEHKYIQVVY--LHNNNISVVGSSDF 165 L +VP +A K + + + L+ N I+ + DF Sbjct: 248 LIKVP-HVALQKVVNLKFLDLNKNPINRIRRGDF 280 >gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] Length = 708 Score = 55.5 bits (132), Expect = 3e-08 Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 22/133 (16%) Query: 54 CPFRCQCHLR-------------VVQCSDLGL-------PPSLTELHLDGNKISRVDAAS 93 CP C C +R V C+DLGL P + L L N I++++ ++ Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88 Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGG-LAEHKYIQVVYL 152 +N L L LS N++S+V N ++ P L ++L+ NKLT +P L+E +Q +Y+ Sbjct: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147 Query: 153 HNNNISVVGSSDF 165 ++N +S + F Sbjct: 148 NHNLLSTISPGAF 160 Score = 42.0 bits (97), Expect = 4e-04 Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P L ++L+ NK++ + L L+NL +L ++ N +S + G+ +L LHL++N+ Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175 Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNP 186 L + + ++++ + N I + +F P N + +G++L P Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNF-KPLINLRSLVIAGINLTEIP 228 Score = 33.9 bits (76), Expect = 0.10 Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P+L L + N I R+ + K L NL L ++ +++ + + +L +L + +N+ Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247 Query: 134 LTRVPGGLAEHKYIQVVY--LHNNNISVVGSSDF 165 L +VP +A K + + + L+ N I+ + DF Sbjct: 248 LIKVP-HVALQKVVNLKFLDLNKNPINRIRRGDF 280 >gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] Length = 708 Score = 55.5 bits (132), Expect = 3e-08 Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 22/133 (16%) Query: 54 CPFRCQCHLR-------------VVQCSDLGL-------PPSLTELHLDGNKISRVDAAS 93 CP C C +R V C+DLGL P + L L N I++++ ++ Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88 Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGG-LAEHKYIQVVYL 152 +N L L LS N++S+V N ++ P L ++L+ NKLT +P L+E +Q +Y+ Sbjct: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147 Query: 153 HNNNISVVGSSDF 165 ++N +S + F Sbjct: 148 NHNLLSTISPGAF 160 Score = 42.0 bits (97), Expect = 4e-04 Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P L ++L+ NK++ + L L+NL +L ++ N +S + G+ +L LHL++N+ Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175 Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNP 186 L + + ++++ + N I + +F P N + +G++L P Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNF-KPLINLRSLVIAGINLTEIP 228 Score = 33.9 bits (76), Expect = 0.10 Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P+L L + N I R+ + K L NL L ++ +++ + + +L +L + +N+ Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247 Query: 134 LTRVPGGLAEHKYIQVVY--LHNNNISVVGSSDF 165 L +VP +A K + + + L+ N I+ + DF Sbjct: 248 LIKVP-HVALQKVVNLKFLDLNKNPINRIRRGDF 280 >gi|149773484 leucine rich repeat and fibronectin type III domain containing 1 [Homo sapiens] Length = 771 Score = 55.1 bits (131), Expect = 4e-08 Identities = 46/132 (34%), Positives = 62/132 (46%), Gaps = 18/132 (13%) Query: 49 SLGPVCPFRCQCH----LRVVQCSDLGL---PPSL----TELHLDGNKISRVDAASLKGL 97 S G CP RC C + C+ GL PP++ EL L N I+ V + Sbjct: 29 SRGQPCPGRCICQNVAPTLTMLCAKTGLLFVPPAIDRRVVELRLTDNFIAAVRRRDFANM 88 Query: 98 NNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG----GLAEHKYIQVVYLH 153 +L L LS N+I V G+ A+ LR LHLD+N+L V G GL +++ L Sbjct: 89 TSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHL---ILG 145 Query: 154 NNNISVVGSSDF 165 NN I V S+ F Sbjct: 146 NNQIRRVESAAF 157 Score = 33.5 bits (75), Expect = 0.14 Identities = 22/78 (28%), Positives = 43/78 (55%), Gaps = 3/78 (3%) Query: 75 SLTELHLDGNKISRVDAASLKG-LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 +L L L N+I RV++A+ L+ + L LS+N++ A+ ++ +L L LD+N Sbjct: 138 NLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNL 197 Query: 134 LTRVPGG--LAEHKYIQV 149 + + G + HK +++ Sbjct: 198 IDHIAEGTFVQLHKLVRL 215 >gi|31542244 leucine rich repeat and fibronectin type III domain containing 5 [Homo sapiens] Length = 719 Score = 55.1 bits (131), Expect = 4e-08 Identities = 35/125 (28%), Positives = 65/125 (52%), Gaps = 12/125 (9%) Query: 53 VCPFRCQCHLR----VVQCSDLGL---PPSL----TELHLDGNKISRVDAASLKGLNNLA 101 +CP RC C + C+ GL PP++ EL L N ++ + + +L Sbjct: 19 ICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLV 78 Query: 102 KLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNNNISVV 160 L LS N+IS + + A+ +LR LHL++N+LT++ + + + + L+NN ++++ Sbjct: 79 DLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLI 138 Query: 161 GSSDF 165 S+ F Sbjct: 139 SSTAF 143 Score = 38.5 bits (88), Expect = 0.004 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 4/79 (5%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +L LHL+ N+++++ GL+NL L L+ N ++ + + + + L EL L N L Sbjct: 100 NLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNL 159 Query: 135 TRVPGGLAEHKYIQVVYLH 153 +P E ++V LH Sbjct: 160 ETIPWDAVE----KMVSLH 174 Score = 35.0 bits (79), Expect = 0.047 Identities = 17/70 (24%), Positives = 36/70 (51%) Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134 +L L L+ N+++ + + + + L +L LS+N++ + ++ L L LD+N + Sbjct: 124 NLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMI 183 Query: 135 TRVPGGLAEH 144 +P G H Sbjct: 184 DNIPKGTFSH 193 >gi|62912472 leucine-rich repeat-containing G protein-coupled receptor 6 isoform 2 [Homo sapiens] Length = 915 Score = 54.7 bits (130), Expect = 6e-08 Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 PSL L LD N IS V S +GL++L L L N+++ + +L N P L+ + L N+ Sbjct: 86 PSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNR 145 Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 165 ++ +P ++ + V++LHNN I +G+ F Sbjct: 146 ISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 178 Score = 42.7 bits (99), Expect = 2e-04 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P+L + L N+IS + + + L +L L L N I + S +L L L+ NK Sbjct: 134 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 193 Query: 134 LTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQY 189 L P + +Q + HNNNI + F + + NP+Q+ Sbjct: 194 LQEFPVAIRTLGRLQELGFHNNNIKAIPEKAF------MGNPLLQTIHFYDNPIQF 243 Score = 37.7 bits (86), Expect = 0.007 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Query: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120 H ++ + L L E+ L N+I + A + L++L L LS+N+I ++ + + Sbjct: 309 HNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFST 368 Query: 121 TPHLRELHLDNNKLTRVP----GGLAEHK 145 L +L L +N+LT +P GGL K Sbjct: 369 LHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397 Score = 35.0 bits (79), Expect = 0.047 Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 10/128 (7%) Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133 P L L L+G + + LKG +L L L+ I + +G P LR L L +N+ Sbjct: 253 PKLHTLSLNG-AMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQ 311 Query: 134 LTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQ 193 + +P L + ++ + L +N I +G+ F ++ +S + L N ++ I Sbjct: 312 IEELP-SLHRCQKLEEIGLQHNRIWEIGADTF------SQLSSLQALDLSWNAIR--SIH 362 Query: 194 PSTFRCVY 201 P F ++ Sbjct: 363 PEAFSTLH 370 Score = 30.8 bits (68), Expect = 0.89 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNI 157 LS N+++ + G + L EL L N L+ +PG Y ++++ L NN + Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 74 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,760,026 Number of Sequences: 37866 Number of extensions: 390098 Number of successful extensions: 1801 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 194 Number of HSP's successfully gapped in prelim test: 56 Number of HSP's that attempted gapping in prelim test: 805 Number of HSP's gapped (non-prelim): 816 length of query: 212 length of database: 18,247,518 effective HSP length: 98 effective length of query: 114 effective length of database: 14,536,650 effective search space: 1657178100 effective search space used: 1657178100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.