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Search of human proteins with 19743850
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743850 decorin isoform c precursor [Homo sapiens]
(212 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743850 decorin isoform c precursor [Homo sapiens] 437 e-123
gi|19743848 decorin isoform b precursor [Homo sapiens] 418 e-117
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 291 3e-79
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 291 3e-79
gi|19743852 decorin isoform d precursor [Homo sapiens] 261 2e-70
gi|41350214 asporin [Homo sapiens] 176 2e-44
gi|4502403 biglycan preproprotein [Homo sapiens] 175 2e-44
gi|19743854 decorin isoform e precursor [Homo sapiens] 155 3e-38
gi|188528675 slit homolog 1 [Homo sapiens] 74 9e-14
gi|11321571 slit homolog 3 [Homo sapiens] 74 1e-13
gi|4759146 slit homolog 2 [Homo sapiens] 68 5e-12
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 60 1e-09
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 60 2e-09
gi|71040111 fibromodulin precursor [Homo sapiens] 60 2e-09
gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] 59 3e-09
gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] 59 3e-09
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 57 9e-09
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 57 9e-09
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 57 1e-08
gi|13375646 leucine rich repeat and fibronectin type III domain ... 57 2e-08
gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom... 56 3e-08
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 56 3e-08
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 56 3e-08
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 55 3e-08
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 55 3e-08
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 55 3e-08
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 55 3e-08
gi|149773484 leucine rich repeat and fibronectin type III domain... 55 4e-08
gi|31542244 leucine rich repeat and fibronectin type III domain ... 55 4e-08
gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 55 6e-08
>gi|19743850 decorin isoform c precursor [Homo sapiens]
Length = 212
Score = 437 bits (1123), Expect = e-123
Identities = 212/212 (100%), Positives = 212/212 (100%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120
HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN
Sbjct: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120
Query: 121 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 180
TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV
Sbjct: 121 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 180
Query: 181 SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 212
SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
Sbjct: 181 SLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 212
>gi|19743848 decorin isoform b precursor [Homo sapiens]
Length = 250
Score = 418 bits (1074), Expect = e-117
Identities = 212/250 (84%), Positives = 212/250 (84%), Gaps = 38/250 (15%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDL--------------------------------------GLPPSLTELHLD 82
HLRVVQCSDL GLPPSLTELHLD
Sbjct: 61 HLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLD 120
Query: 83 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 142
GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA
Sbjct: 121 GNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLA 180
Query: 143 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 202
EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV
Sbjct: 181 EHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 240
Query: 203 RSAIQLGNYK 212
RSAIQLGNYK
Sbjct: 241 RSAIQLGNYK 250
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 291 bits (745), Expect = 3e-79
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 130
GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD
Sbjct: 218 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 277
Query: 131 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 190
NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW
Sbjct: 278 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 337
Query: 191 EIQPSTFRCVYVRSAIQLGNYK 212
EIQPSTFRCVYVRSAIQLGNYK
Sbjct: 338 EIQPSTFRCVYVRSAIQLGNYK 359
Score = 191 bits (486), Expect = 3e-49
Identities = 112/223 (50%), Positives = 136/223 (60%), Gaps = 27/223 (12%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLG-------LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 113
HLRVVQCSDLG LPP T L L NKI+ + K L NL L L N IS V
Sbjct: 61 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 120
Query: 114 DNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK 173
G+ L L+L N+L +P + K +Q + H N I+ V +
Sbjct: 121 SPGAFTPLVKLERLYLSKNQLKELPEKMP--KTLQELRAHENEITKV------------R 166
Query: 174 KASYSG------VSLFSNPVQYWEIQPSTFRCVYVRSAIQLGN 210
K +++G + L +NP++ I+ F+ + S I++ +
Sbjct: 167 KVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIAD 209
Score = 41.2 bits (95), Expect = 7e-04
Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHL 129
+P +L EL N+I++V + GLN + + L N + S ++NG+ L + +
Sbjct: 148 MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRI 207
Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 163
+ +T +P GL + ++L N IS V ++
Sbjct: 208 ADTNITSIPQGLPPS--LTELHLDGNKISRVDAA 239
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 291 bits (745), Expect = 3e-79
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 130
GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD
Sbjct: 218 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLD 277
Query: 131 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 190
NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW
Sbjct: 278 NNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYW 337
Query: 191 EIQPSTFRCVYVRSAIQLGNYK 212
EIQPSTFRCVYVRSAIQLGNYK
Sbjct: 338 EIQPSTFRCVYVRSAIQLGNYK 359
Score = 191 bits (486), Expect = 3e-49
Identities = 112/223 (50%), Positives = 136/223 (60%), Gaps = 27/223 (12%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLG-------LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 113
HLRVVQCSDLG LPP T L L NKI+ + K L NL L L N IS V
Sbjct: 61 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 120
Query: 114 DNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK 173
G+ L L+L N+L +P + K +Q + H N I+ V +
Sbjct: 121 SPGAFTPLVKLERLYLSKNQLKELPEKMP--KTLQELRAHENEITKV------------R 166
Query: 174 KASYSG------VSLFSNPVQYWEIQPSTFRCVYVRSAIQLGN 210
K +++G + L +NP++ I+ F+ + S I++ +
Sbjct: 167 KVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIAD 209
Score = 41.2 bits (95), Expect = 7e-04
Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI--SAVDNGSLANTPHLRELHL 129
+P +L EL N+I++V + GLN + + L N + S ++NG+ L + +
Sbjct: 148 MPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRI 207
Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 163
+ +T +P GL + ++L N IS V ++
Sbjct: 208 ADTNITSIPQGLPPS--LTELHLDGNKISRVDAA 239
>gi|19743852 decorin isoform d precursor [Homo sapiens]
Length = 172
Score = 261 bits (668), Expect = 2e-70
Identities = 141/219 (64%), Positives = 145/219 (66%), Gaps = 54/219 (24%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLG-------LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV 113
HLRVVQCSDLG LPP T L L NKI+ + K L NL + L N+IS V
Sbjct: 61 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHVVYLHNNNISVV 120
Query: 114 DNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK 173
GSSDFCPPGHNTK
Sbjct: 121 -----------------------------------------------GSSDFCPPGHNTK 133
Query: 174 KASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 212
KASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
Sbjct: 134 KASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 172
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 176 bits (445), Expect = 2e-44
Identities = 81/155 (52%), Positives = 112/155 (72%), Gaps = 4/155 (2%)
Query: 61 HLRVVQCS----DLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 116
H+R+ + GLPP+L ELHLD NKIS V+ K L +LGL N I+ ++NG
Sbjct: 224 HIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENG 283
Query: 117 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKAS 176
SLAN P +RE+HL+NNKL ++P GL E KY+Q+++LH+N+I+ VG +DFCP KK+
Sbjct: 284 SLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSL 343
Query: 177 YSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 211
YS +SLF+NPV+YWE+QP+TFRCV R ++QLGN+
Sbjct: 344 YSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNF 378
Score = 79.7 bits (195), Expect = 2e-15
Identities = 70/231 (30%), Positives = 99/231 (42%), Gaps = 38/231 (16%)
Query: 1 MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45
MK ++LL LA S A PF L + ML+D + DD D
Sbjct: 1 MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59
Query: 46 -------FEPSLGPVCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDA 91
F L P+CPF CQC+ RVV CSDLGL P L L NKI +
Sbjct: 60 REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119
Query: 92 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 151
KGL +L L L+ N ++ + + T LR L+L +N+L+ +P L K + +
Sbjct: 120 NDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP--KSLAELR 177
Query: 152 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 202
+H N + + F G N + + +NP+ I+P F V V
Sbjct: 178 IHENKVKKIQKDTF--KGMNALHV----LEMSANPLDNNGIEPGAFEGVTV 222
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 175 bits (444), Expect = 2e-44
Identities = 84/141 (59%), Positives = 103/141 (73%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131
LP +L ELHLD NKI ++ L + L +LGL N I ++NGSL+ P LRELHLDN
Sbjct: 227 LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDN 286
Query: 132 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWE 191
NKL RVP GL + K +QVVYLH+NNI+ VG +DFCP G K+A Y+G+SLF+NPV YWE
Sbjct: 287 NKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWE 346
Query: 192 IQPSTFRCVYVRSAIQLGNYK 212
+QP+TFRCV R AIQ GNYK
Sbjct: 347 VQPATFRCVTDRLAIQFGNYK 367
Score = 95.9 bits (237), Expect = 2e-20
Identities = 69/207 (33%), Positives = 98/207 (47%), Gaps = 24/207 (11%)
Query: 7 LLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLGPVCPFR 57
L+ L +S A PF+QRG +DF L+D EASG V D P+ +CPF
Sbjct: 7 LVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFG 66
Query: 58 CQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSI 110
C CHLRVVQCSDLGL P T L L N IS + KGL +L L L N I
Sbjct: 67 CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 111 SAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGH 170
S + + + L++L++ N L +P L + + +H+N I V P G
Sbjct: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSS--LVELRIHDNRIRKV------PKGV 178
Query: 171 NTKKASYSGVSLFSNPVQYWEIQPSTF 197
+ + + + + NP++ +P F
Sbjct: 179 FSGLRNMNCIEMGGNPLENSGFEPGAF 205
>gi|19743854 decorin isoform e precursor [Homo sapiens]
Length = 75
Score = 155 bits (391), Expect = 3e-38
Identities = 73/75 (97%), Positives = 73/75 (97%)
Query: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC
Sbjct: 1 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 60
Query: 61 HLRVVQCSDLGLPPS 75
HLRVVQCSDLG PS
Sbjct: 61 HLRVVQCSDLGCLPS 75
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 73.9 bits (180), Expect = 9e-14
Identities = 51/165 (30%), Positives = 81/165 (49%), Gaps = 17/165 (10%)
Query: 53 VCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASL-KGLNNLAKLG 104
VCP +C+C VV+CS L L P S EL L+ N+IS ++A + K L +L K+
Sbjct: 512 VCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKIN 571
Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSS 163
LS N +S +++G+ + ELHL N+L + G+ ++ + L NN IS + +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631
Query: 164 DFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQL 208
F T + +SL+ N Q + P F + S + L
Sbjct: 632 SF------TGLRNVRLLSLYDN--QITTVSPGAFDTLQSLSTLNL 668
Score = 52.0 bits (123), Expect = 4e-07
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106
CP C C V C GL P + L L+GN I+R+ GL L L L
Sbjct: 34 CPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLM 93
Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVP 138
N I AV+ G+ + L L L+ N+L +P
Sbjct: 94 ENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Score = 51.6 bits (122), Expect = 5e-07
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 14/143 (9%)
Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106
CP C C +V C GL P ++TE+ L+ N I + + L ++ LS
Sbjct: 282 CPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341
Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNISVVGSSDF 165
N I+ + + L L L NK+T +P G+ Y +Q++ L+ N I+ + F
Sbjct: 342 NNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 401
Query: 166 CPPGHNTKKASYSGVSLFSNPVQ 188
+ S +SL+ N +Q
Sbjct: 402 ------QDLQNLSLLSLYDNKIQ 418
Score = 46.2 bits (108), Expect = 2e-05
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 30/120 (25%)
Query: 52 PVCPFRCQCHLRVVQCSDL-------GLPPSLTELHLDGN-------------------- 84
P CP C C VV+CS+ G+P ++TEL+LDGN
Sbjct: 732 PQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791
Query: 85 ---KISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL 141
KIS + +S ++ L L LS+N++ + + LR L L N ++ + G+
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851
Score = 44.7 bits (104), Expect = 6e-05
Identities = 21/43 (48%), Positives = 30/43 (69%)
Query: 123 HLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165
++ EL+LD N+ T VPG L+ KY+Q+V L NN IS + +S F
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSF 804
Score = 36.6 bits (83), Expect = 0.016
Identities = 20/59 (33%), Positives = 31/59 (52%)
Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
L L LD N+IS ++ + + L L L L+ N+I+ + S + P LR L +N L
Sbjct: 159 LKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 31.6 bits (70), Expect = 0.52
Identities = 18/58 (31%), Positives = 31/58 (53%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNN 132
+L L L+ NKI+ + + + L NL+ L L N I ++ G+ + ++ LHL N
Sbjct: 382 TLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 73.6 bits (179), Expect = 1e-13
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 21/149 (14%)
Query: 50 LGPVCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAK 102
L P CP +C C VV+CS+ GL P +TEL+L+GN ++ V L L +L
Sbjct: 721 LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPR-ELSALRHLTL 779
Query: 103 LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHKYIQVVYLHNNNIS 158
+ LS NSIS + N + +N HL L L N+L +P GL + ++V+ LH N+IS
Sbjct: 780 IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGL---RSLRVLTLHGNDIS 836
Query: 159 VVGSSDFCPPGHNTKKASYSGVSLFSNPV 187
V P G S S ++L +NP+
Sbjct: 837 SV------PEGSFNDLTSLSHLALGTNPL 859
Score = 61.2 bits (147), Expect = 6e-10
Identities = 48/161 (29%), Positives = 73/161 (45%), Gaps = 27/161 (16%)
Query: 53 VCPFRCQCHLRVVQCSD-------LGLPPSLTELHLDGNKISRVDAASL-KGLNNLAKLG 104
VCP +C+C +V CS+ LP +T+L L+ N++S ++A + K L NL K+
Sbjct: 504 VCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKIN 563
Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVYLHNNNISVVGSS 163
LS N I V G+ ++EL L N+L V G + ++ + L +N I V +
Sbjct: 564 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 623
Query: 164 DFC------------------PPGHNTKKASYSGVSLFSNP 186
F PG T S S ++L SNP
Sbjct: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664
Score = 58.5 bits (140), Expect = 4e-09
Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 7/92 (7%)
Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106
CP +C C V C LGL P + L LD N I+R+ GL NL L L
Sbjct: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVP 138
N +S ++ G+ + L L L+ NKL +P
Sbjct: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Score = 43.9 bits (102), Expect = 1e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P LT L L N+I + + +G+ ++ L L N IS +++G+ L L L+NN
Sbjct: 133 PKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNN 192
Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNI 157
++R+ H I+ + LH+N++
Sbjct: 193 ISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 38.9 bits (89), Expect = 0.003
Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
SLT L L GNKI+ + GL +L L L+ N I+ + + + +L L L +NKL
Sbjct: 356 SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415
Query: 135 TRVPGGL-AEHKYIQVVYLHNN 155
+ GL A + IQ ++L N
Sbjct: 416 QTISKGLFAPLQSIQTLHLAQN 437
Score = 36.2 bits (82), Expect = 0.021
Identities = 32/146 (21%), Positives = 57/146 (39%), Gaps = 32/146 (21%)
Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGN--------------KISRVDAA 92
CP C C +V C GL P + E+ L+ N K+ R+D +
Sbjct: 280 CPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDIS 339
Query: 93 ----------SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGL 141
+ +GL +L L L N I+ + G L+ L L+ NK+ +
Sbjct: 340 KNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTF 399
Query: 142 AEHKYIQVVYLHNNNISVVGSSDFCP 167
+ + + ++ L++N + + F P
Sbjct: 400 QDLQNLNLLSLYDNKLQTISKGLFAP 425
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 68.2 bits (165), Expect = 5e-12
Identities = 52/156 (33%), Positives = 80/156 (51%), Gaps = 17/156 (10%)
Query: 42 DDRDFEPSLGPV--CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAA 92
DD + + S P+ CP C C VV+CS+ GL P +TEL+LDGN+ + V
Sbjct: 713 DDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPK- 771
Query: 93 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH-KYIQVVY 151
L +L + LS N IS + N S +N L L L N+L +P + K ++++
Sbjct: 772 ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLS 831
Query: 152 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 187
LH N+ISVV P G ++ S +++ +NP+
Sbjct: 832 LHGNDISVV------PEGAFNDLSALSHLAIGANPL 861
Score = 52.8 bits (125), Expect = 2e-07
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106
CP +C C V C L L P + L L+GN I+R+ GL +L L L
Sbjct: 28 CPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLM 87
Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVP 138
N IS ++ G+ + L L L+ N L P
Sbjct: 88 ENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Score = 51.6 bits (122), Expect = 5e-07
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 54 CPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106
CP C C +V C GL P ++TE+ L+ N I + + L ++ LS
Sbjct: 273 CPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLS 332
Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNIS 158
N IS + + L L L NK+T +P L E + +Q++ L+ N I+
Sbjct: 333 NNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKIN 385
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT 135
L L L N+I + + +G ++ L L +N IS +++G+ L L L+NN +T
Sbjct: 129 LYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNIT 188
Query: 136 RVPGGLAEH-KYIQVVYLHNNNI 157
R+ H ++ LH+NN+
Sbjct: 189 RLSVASFNHMPKLRTFRLHSNNL 211
Score = 38.9 bits (89), Expect = 0.003
Identities = 39/189 (20%), Positives = 74/189 (39%), Gaps = 51/189 (26%)
Query: 40 VPDDRDFEPSLGP------VCPFRCQCHLRVVQCSDLGLP-------------------- 73
+P D+ L CP +C+C V CS+ L
Sbjct: 486 IPGTEDYRSKLSGDCFADLACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEF 545
Query: 74 ------------PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121
P L +++ NKI+ ++ + +G + + ++ L+ N + V +
Sbjct: 546 TVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGL 605
Query: 122 PHLRELHLDNNKLTRVPG----GLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASY 177
L+ L L +N++T V GL+ ++++ L++N I+ V PG S
Sbjct: 606 ESLKTLMLRSNRITCVGNDSFIGLSS---VRLLSLYDNQITTVA------PGAFDTLHSL 656
Query: 178 SGVSLFSNP 186
S ++L +NP
Sbjct: 657 STLNLLANP 665
Score = 35.0 bits (79), Expect = 0.047
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
SL L L GNKI+ + + +GL +L L L+ N I+ + + + +L L L +NKL
Sbjct: 349 SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKL 408
Query: 135 -TRVPGGLAEHKYIQVVYLHNN 155
T G + + IQ ++L N
Sbjct: 409 QTIAKGTFSPLRAIQTMHLAQN 430
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 60.1 bits (144), Expect = 1e-09
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 13/131 (9%)
Query: 48 PSLGPVCPFRCQCH-----------LRVV-QCSDLGLPPSLTELHLDGNKISRVDAASLK 95
P PVCP RC C LRVV + S L P + L GN I+ + A
Sbjct: 21 PLAEPVCPERCDCQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFH 80
Query: 96 GLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHN 154
L L +L L +N I ++ + L EL+L NN L + PG LA + ++++Y +
Sbjct: 81 RLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANG 140
Query: 155 NNISVVGSSDF 165
N IS + F
Sbjct: 141 NEISRLSRGSF 151
Score = 48.9 bits (115), Expect = 3e-06
Identities = 26/67 (38%), Positives = 42/67 (62%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+L EL L+GN++S++ A L+ L++L L LS N +SA+ + + LREL L NN L
Sbjct: 278 ALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 337
Query: 135 TRVPGGL 141
+ + G +
Sbjct: 338 SALSGDI 344
Score = 43.5 bits (101), Expect = 1e-04
Identities = 21/56 (37%), Positives = 36/56 (64%)
Query: 79 LHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
L+ +GN+ISR+ S +GL +L KL L N++ A+ + A +L LHL++N++
Sbjct: 136 LYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRI 191
Score = 35.8 bits (81), Expect = 0.028
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 8/123 (6%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
SL+ L L N + + + L L L L N ++ + + LREL L+ N+L
Sbjct: 230 SLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRL 289
Query: 135 TRVPGGLAEHKY-IQVVYLHNNNISVVGSSDFCPPG-------HNTKKASYSGVSLFSNP 186
+++P L E + ++ + L N +S + + F G N ++ SG ++P
Sbjct: 290 SQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASP 349
Query: 187 VQY 189
Y
Sbjct: 350 ALY 352
Score = 27.7 bits (60), Expect = 7.5
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 11/122 (9%)
Query: 79 LHLDGNKI--SRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTR 136
L+L N++ S AA+ L +L+ L LS N++ + + P L L L N+LT
Sbjct: 208 LNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTH 267
Query: 137 V-PGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPS 195
+ P + ++ + L N +S + ++ P H+ + SG L + + P+
Sbjct: 268 LAPEAFWGLEALRELRLEGNRLSQLPTA-LLEPLHSLEALDLSGNELSA-------LHPA 319
Query: 196 TF 197
TF
Sbjct: 320 TF 321
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 59.7 bits (143), Expect = 2e-09
Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 8/113 (7%)
Query: 54 CPFRCQCHLRVVQCS-------DLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 106
CP C+C+ V+C LG+PP L L N I+R++ +L L L +L L
Sbjct: 23 CPAACRCYSATVECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLH 82
Query: 107 FNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNIS 158
NS+ A++ G+ P L EL L +N+L + G ++V+YL N ++
Sbjct: 83 NNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLA 135
Score = 39.3 bits (90), Expect = 0.002
Identities = 22/59 (37%), Positives = 31/59 (52%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNN 132
P L ELHL N I ++ +L GL++LA L LS N + + +L L+ L L N
Sbjct: 146 PRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTEN 204
Score = 38.1 bits (87), Expect = 0.006
Identities = 21/73 (28%), Positives = 37/73 (50%)
Query: 62 LRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121
LR ++ P L EL L N++ + + + GL L L L+ N ++ + + + +
Sbjct: 86 LRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHL 145
Query: 122 PHLRELHLDNNKL 134
P L+ELHL N +
Sbjct: 146 PRLQELHLQENSI 158
Score = 30.8 bits (68), Expect = 0.89
Identities = 20/59 (33%), Positives = 32/59 (54%)
Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
L L+L GN+++R+ + L L +L L NSI +++ +LA L L L N+L
Sbjct: 124 LRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQL 182
Score = 30.0 bits (66), Expect = 1.5
Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 122 PHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNISVVGSSDF 165
P + L L +N + R+ PG LA ++ +YLHNN++ + + F
Sbjct: 50 PGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAF 94
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 59.7 bits (143), Expect = 2e-09
Identities = 40/94 (42%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131
LP SL ELHLD N+ISRV +L+GL NL L L N I V S+ L L L
Sbjct: 174 LPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEV-GSSMRGLRSLILLDLSY 232
Query: 132 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165
N L +VP GL ++ +Y+ +NN+ V S F
Sbjct: 233 NHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYF 264
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 11/109 (10%)
Query: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120
HLR V GLP +L +L+++ N + V + +G L + LS NS++ +NG +N
Sbjct: 234 HLRKVPD---GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLT--NNGLASN 288
Query: 121 T---PHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFC 166
T L EL L N+L ++P + ++ +YL N I+ S FC
Sbjct: 289 TFNSSSLLELDLSYNQLQKIP---PVNTNLENLYLQGNRINEFSISSFC 334
Score = 44.7 bits (104), Expect = 6e-05
Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 21/134 (15%)
Query: 38 PEVPDDRDFEPSLGPVCPFRCQCHLR---VVQCSDLGL------PPSLTELHLDGNKISR 88
P PD RD CP C C + C + L P + ++ N+I+
Sbjct: 68 PSPPDPRD--------CPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITS 119
Query: 89 VDAASLKGLNNLAKLGLSFNSISA--VDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY 146
+ L + L N I++ V + HL L+LD+N LTR+PG L +
Sbjct: 120 IQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLP--RS 177
Query: 147 IQVVYLHNNNISVV 160
++ ++L +N IS V
Sbjct: 178 LRELHLDHNQISRV 191
>gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens]
Length = 522
Score = 58.9 bits (141), Expect = 3e-09
Identities = 44/130 (33%), Positives = 66/130 (50%), Gaps = 15/130 (11%)
Query: 48 PSLGPVCPFRCQCHLRVVQCSDLGL---PPSL----TELHLDGNKISRVDA----ASLKG 96
P VCP C C +V C++ L P +L L L N+I +D+ S
Sbjct: 35 PGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAK 94
Query: 97 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNN 155
LN L L N+I+++ GS + TP+L+ L L +NKL V + E K ++V+ L+NN
Sbjct: 95 LNTLI---LRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNN 151
Query: 156 NISVVGSSDF 165
+IS + S F
Sbjct: 152 HISYLDPSAF 161
Score = 35.4 bits (80), Expect = 0.036
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P+L L L NK+ V A + L L L L N IS +D + L++L+L N
Sbjct: 117 PNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNF 176
Query: 134 LTRVPGG-------LAEHKYIQVVY 151
LT+ P LAE ++ V Y
Sbjct: 177 LTQFPMDLYVGRFKLAELMFLDVSY 201
>gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens]
Length = 522
Score = 58.9 bits (141), Expect = 3e-09
Identities = 44/130 (33%), Positives = 66/130 (50%), Gaps = 15/130 (11%)
Query: 48 PSLGPVCPFRCQCHLRVVQCSDLGL---PPSL----TELHLDGNKISRVDA----ASLKG 96
P VCP C C +V C++ L P +L L L N+I +D+ S
Sbjct: 35 PGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAK 94
Query: 97 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNN 155
LN L L N+I+++ GS + TP+L+ L L +NKL V + E K ++V+ L+NN
Sbjct: 95 LNTLI---LRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNN 151
Query: 156 NISVVGSSDF 165
+IS + S F
Sbjct: 152 HISYLDPSAF 161
Score = 35.4 bits (80), Expect = 0.036
Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P+L L L NK+ V A + L L L L N IS +D + L++L+L N
Sbjct: 117 PNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNF 176
Query: 134 LTRVPGG-------LAEHKYIQVVY 151
LT+ P LAE ++ V Y
Sbjct: 177 LTQFPMDLYVGRFKLAELMFLDVSY 201
>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 57.4 bits (137), Expect = 9e-09
Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 27/128 (21%)
Query: 54 CPFRCQCHLR-------------VVQCSDLGL---PPSLTE----LHLDGNKISRVDAAS 93
CP +C C +R V C+DL L PP+L L L N I RVD +
Sbjct: 29 CPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSE 88
Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHKYIQV 149
L L NL +L LS NS S + P L LHL+ N+LTR+ GLA +Q
Sbjct: 89 LGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS---LQE 145
Query: 150 VYLHNNNI 157
+YL++N +
Sbjct: 146 LYLNHNQL 153
Score = 41.2 bits (95), Expect = 7e-04
Identities = 21/63 (33%), Positives = 37/63 (58%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
SL EL+L+ N++ R+ + GL+NL +L L+ N + A+D+ P+L L + NK+
Sbjct: 142 SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKV 201
Query: 135 TRV 137
+
Sbjct: 202 DAI 204
Score = 39.3 bits (90), Expect = 0.002
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Query: 62 LRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121
LR + + P+L L + GNK+ + + + L NL L L+ ++ + + +L
Sbjct: 177 LRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGL 236
Query: 122 PHLRELHLDNNKLTRVP-GGLAEHKYIQVVYLHNNNISVVGSSDF 165
L L +N+L RVP L + ++ + L+ N + VG DF
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDF 281
Score = 36.6 bits (83), Expect = 0.016
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS-FNSISAVDNGSLANTPHLRELHLDNN 132
P L L L+ N + RV + +L +LGL+ + ++D +L N P L +L + NN
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNN 320
Query: 133 -KLTRV-PGGLAEHKYIQVVYLHNNNISVV 160
+L+ + P ++ + L+NN +S +
Sbjct: 321 PRLSFIHPRAFHHLPQMETLMLNNNALSAL 350
Score = 35.8 bits (81), Expect = 0.028
Identities = 21/57 (36%), Positives = 31/57 (54%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131
SL L N+++RV +L+ + L L L+ N + V G AN HL+EL L+N
Sbjct: 238 SLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 57.4 bits (137), Expect = 9e-09
Identities = 46/128 (35%), Positives = 61/128 (47%), Gaps = 27/128 (21%)
Query: 54 CPFRCQCHLR-------------VVQCSDLGL---PPSLTE----LHLDGNKISRVDAAS 93
CP +C C +R V C+DL L PP+L L L N I RVD +
Sbjct: 29 CPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSE 88
Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVP----GGLAEHKYIQV 149
L L NL +L LS NS S + P L LHL+ N+LTR+ GLA +Q
Sbjct: 89 LGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLAS---LQE 145
Query: 150 VYLHNNNI 157
+YL++N +
Sbjct: 146 LYLNHNQL 153
Score = 41.2 bits (95), Expect = 7e-04
Identities = 21/63 (33%), Positives = 37/63 (58%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
SL EL+L+ N++ R+ + GL+NL +L L+ N + A+D+ P+L L + NK+
Sbjct: 142 SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKV 201
Query: 135 TRV 137
+
Sbjct: 202 DAI 204
Score = 39.3 bits (90), Expect = 0.002
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Query: 62 LRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANT 121
LR + + P+L L + GNK+ + + + L NL L L+ ++ + + +L
Sbjct: 177 LRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGL 236
Query: 122 PHLRELHLDNNKLTRVP-GGLAEHKYIQVVYLHNNNISVVGSSDF 165
L L +N+L RVP L + ++ + L+ N + VG DF
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDF 281
Score = 36.6 bits (83), Expect = 0.016
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS-FNSISAVDNGSLANTPHLRELHLDNN 132
P L L L+ N + RV + +L +LGL+ + ++D +L N P L +L + NN
Sbjct: 261 PGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNN 320
Query: 133 -KLTRV-PGGLAEHKYIQVVYLHNNNISVV 160
+L+ + P ++ + L+NN +S +
Sbjct: 321 PRLSFIHPRAFHHLPQMETLMLNNNALSAL 350
Score = 35.8 bits (81), Expect = 0.028
Identities = 21/57 (36%), Positives = 31/57 (54%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 131
SL L N+++RV +L+ + L L L+ N + V G AN HL+EL L+N
Sbjct: 238 SLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 57.0 bits (136), Expect = 1e-08
Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 5/141 (3%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLN-NLAKLGLSFNSIS--AVDNGSLANTPH-LREL 127
LP SL L L GN+I R+ + L L LSFN ++ +D S H LREL
Sbjct: 554 LPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLREL 613
Query: 128 HLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 187
LD+N L +P G+ E K + + L+NN I + + C ++ + L +N +
Sbjct: 614 FLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEIC-NAEEDDDSNLEHLHLENNYI 672
Query: 188 QYWEIQPSTFRCVYVRSAIQL 208
+ EI TF C+ S+I L
Sbjct: 673 KIREIPSYTFSCIRSYSSIVL 693
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 11/115 (9%)
Query: 55 PFRCQCHLRVVQCSDLGLP-------PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSF 107
P C R + C + L P +T L L GN I+ + + GL NL +L LS
Sbjct: 317 PSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSK 376
Query: 108 NSISAVDNGSLA--NTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVV 160
N+I++ G A L L++D N L ++P L ++ + ++ NN+ +
Sbjct: 377 NNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLP--STLEELKVNENNLQAI 429
Score = 35.4 bits (80), Expect = 0.036
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLA--NTPHLRELH 128
GLP S+ EL+L+ N+I + + + L +N I LA N +L +
Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESID 541
Query: 129 LDNNKLTRVPGGLAEHKYIQVVYLHN 154
L NKL VP L + + +V L N
Sbjct: 542 LSYNKLYHVPSYLPK-SLLHLVLLGN 566
>gi|13375646 leucine rich repeat and fibronectin type III domain
containing 3 [Homo sapiens]
Length = 628
Score = 56.6 bits (135), Expect = 2e-08
Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 14/141 (9%)
Query: 54 CPFRCQCHLRV----VQCSDLGL---PPSL----TELHLDGNKISRVDAASLKGLNNLAK 102
CP RC+C + V C GL PPSL EL L N I+ V L + L
Sbjct: 28 CPRRCRCQTQSLPLSVLCPGAGLLFVPPSLDRRAAELRLADNFIASVRRRDLANMTGLLH 87
Query: 103 LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV-PGGLAEHKYIQVVYLHNNNISVV- 160
L LS N+I V G+ A+ LR LHLD N+LT + G L ++ + L NN ++ +
Sbjct: 88 LSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALA 147
Query: 161 -GSSDFCPPGHNTKKASYSGV 180
G+ D C SY+ +
Sbjct: 148 AGALDDCAETLEDLDLSYNNL 168
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 25/91 (27%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRE-------- 126
+L LHLDGN+++ + L+GL NL L LS N ++A+ G+L + E
Sbjct: 108 ALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDCAETLEDLDLSYNN 167
Query: 127 -----------------LHLDNNKLTRVPGG 140
L LD+N L VP G
Sbjct: 168 LEQLPWEALGRLGNVNTLGLDHNLLASVPAG 198
Score = 37.0 bits (84), Expect = 0.012
Identities = 19/64 (29%), Positives = 35/64 (54%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+L +L L N + ++ +L L N+ LGL N +++V G+ + L L + +N+L
Sbjct: 157 TLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLARLDMTSNRL 216
Query: 135 TRVP 138
T +P
Sbjct: 217 TTIP 220
>gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo
sapiens]
Length = 592
Score = 55.8 bits (133), Expect = 3e-08
Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 9/97 (9%)
Query: 54 CPFRCQCHL--RVVQCSDL-------GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLG 104
CP RC+C + R V C+ G+P L L N+I ++ L L L +L
Sbjct: 25 CPARCECTVQTRAVACTRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPALEELD 84
Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL 141
LS N+I+ V+ G+ AN P LR L L N+L +P G+
Sbjct: 85 LSENAIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGV 121
Score = 47.4 bits (111), Expect = 9e-06
Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+LT L + I+ V AA+L+ +L L LS N IS V GS + LRELHL L
Sbjct: 247 NLTSLSVTHTNITAVPAAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALL 306
Query: 135 TRV-PGGLAEHKYIQVVYLHNNNISVVGSSDF 165
V P + I+++ L NN +S + S F
Sbjct: 307 AVVEPQAFLGLRQIRLLNLSNNLLSTLEESTF 338
Score = 40.0 bits (92), Expect = 0.001
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
Query: 61 HLRVVQCSDLGLP--PSLTELHLDG-NKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 117
HL + D P L L +D + V A SL+GLN L L ++ +I+AV +
Sbjct: 207 HLAIASLEDQNFRRLPGLLHLEIDNWPLLEEVAAGSLRGLN-LTSLSVTHTNITAVPAAA 265
Query: 118 LANTPHLRELHLDNNKLTRVPGG 140
L + HL L+L +N ++ VP G
Sbjct: 266 LRHQAHLTCLNLSHNPISTVPRG 288
Score = 29.3 bits (64), Expect = 2.6
Identities = 19/64 (29%), Positives = 30/64 (46%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P L L L GN++ + L+NL L LS N + + + + + LR L + +N
Sbjct: 102 PRLRVLRLRGNQLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLHSLRRLEVGDND 161
Query: 134 LTRV 137
L V
Sbjct: 162 LVFV 165
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 55.8 bits (133), Expect = 3e-08
Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 32/139 (23%)
Query: 54 CPFRCQCHLRVVQCSD-------LGLPPSLTELHLDGNKISRVDAAS-LKGL-------- 97
CP C+C + C+D G+P T L+L N+I+ S LK L
Sbjct: 31 CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYL 90
Query: 98 ---------NNLAK----LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV---PGGL 141
NL K L L N+I + SL+ P+L ELHLD+N ++ V G
Sbjct: 91 YHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAF 150
Query: 142 AEHKYIQVVYLHNNNISVV 160
+ Y+++++L N++S +
Sbjct: 151 RDSNYLRLLFLSRNHLSTI 169
Score = 50.8 bits (120), Expect = 8e-07
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 4/93 (4%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV--DNGSLANTPHLRELHL 129
LP + ELHL N I + SL + L +L L NS+SAV + G+ ++ +LR L L
Sbjct: 102 LPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFL 161
Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 162
N L+ +P GL + I+ + L +N IS + S
Sbjct: 162 SRNHLSTIPWGLP--RTIEELRLDDNRISTISS 192
Score = 50.4 bits (119), Expect = 1e-06
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELH 128
GLP ++ EL LD N+IS + + SL+GL +L +L L N ++ + + N +L EL
Sbjct: 172 GLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELS 231
Query: 129 LDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165
L N LT P L ++ +YL +N+I+ V + F
Sbjct: 232 LVRNSLTAAPVNLPGTN-LRKLYLQDNHINRVPPNAF 267
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 55.8 bits (133), Expect = 3e-08
Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 32/139 (23%)
Query: 54 CPFRCQCHLRVVQCSD-------LGLPPSLTELHLDGNKISRVDAAS-LKGL-------- 97
CP C+C + C+D G+P T L+L N+I+ S LK L
Sbjct: 31 CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYL 90
Query: 98 ---------NNLAK----LGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV---PGGL 141
NL K L L N+I + SL+ P+L ELHLD+N ++ V G
Sbjct: 91 YHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAF 150
Query: 142 AEHKYIQVVYLHNNNISVV 160
+ Y+++++L N++S +
Sbjct: 151 RDSNYLRLLFLSRNHLSTI 169
Score = 50.8 bits (120), Expect = 8e-07
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 4/93 (4%)
Query: 72 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAV--DNGSLANTPHLRELHL 129
LP + ELHL N I + SL + L +L L NS+SAV + G+ ++ +LR L L
Sbjct: 102 LPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFL 161
Query: 130 DNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGS 162
N L+ +P GL + I+ + L +N IS + S
Sbjct: 162 SRNHLSTIPWGLP--RTIEELRLDDNRISTISS 192
Score = 50.4 bits (119), Expect = 1e-06
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Query: 71 GLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS--AVDNGSLANTPHLRELH 128
GLP ++ EL LD N+IS + + SL+GL +L +L L N ++ + + N +L EL
Sbjct: 172 GLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELS 231
Query: 129 LDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDF 165
L N LT P L ++ +YL +N+I+ V + F
Sbjct: 232 LVRNSLTAAPVNLPGTN-LRKLYLQDNHINRVPPNAF 267
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 55.5 bits (132), Expect = 3e-08
Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 10/122 (8%)
Query: 54 CPFRCQCHLR---------VVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLG 104
CP C+C R V + S LGLP +LT + L G + + S G+ L +L
Sbjct: 21 CPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQSQSFSGMTVLQRLM 80
Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHK-YIQVVYLHNNNISVVGSS 163
+S + ISAV G+ ++ L+ L L NK+T +PG L + ++ ++L +N + + +
Sbjct: 81 ISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQN 140
Query: 164 DF 165
F
Sbjct: 141 MF 142
Score = 38.5 bits (88), Expect = 0.004
Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+LTEL N I + + L NL+ L LS N ++ + + ++ +L L L N L
Sbjct: 219 ALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPL 278
Query: 135 TRVPGGL-AEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSL 182
+PG L E +Q ++L+ + + ++ F N + Y GV+L
Sbjct: 279 AELPGVLFGEMGGLQELWLNRTQLRTLPAAAF----RNLSRLRYLGVTL 323
Score = 35.8 bits (81), Expect = 0.028
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 76 LTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLT 135
L L L N ++ + L+GL L ++ L N + A+ N L + LD+N+L
Sbjct: 341 LQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Query: 136 RVPGGL--AEHKYIQVVYLHNN 155
+PG + A + +V+ HN+
Sbjct: 401 TLPGDVFGALPRLTEVLLGHNS 422
Score = 34.7 bits (78), Expect = 0.061
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 85 KISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH 144
++S + + +GL L L L N ++A+ +G L LR++ L N+L +P L +
Sbjct: 326 RLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRN 385
Query: 145 -KYIQVVYLHNNNISVVGSSDF 165
++ V L +N + + F
Sbjct: 386 LSSLESVQLDHNQLETLPGDVF 407
Score = 33.1 bits (74), Expect = 0.18
Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 7/114 (6%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+L L L GN ++ + L L +L L N + ++D+G L + L EL N +
Sbjct: 171 NLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHI 230
Query: 135 TRV-PGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPV 187
+ PG + + L N+++ + S+ F HN + ++LF NP+
Sbjct: 231 RSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFL-HSHN-----LTLLTLFENPL 278
>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 55.5 bits (132), Expect = 3e-08
Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 22/133 (16%)
Query: 54 CPFRCQCHLR-------------VVQCSDLGL-------PPSLTELHLDGNKISRVDAAS 93
CP C C +R V C+DLGL P + L L N I++++ ++
Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGG-LAEHKYIQVVYL 152
+N L L LS N++S+V N ++ P L ++L+ NKLT +P L+E +Q +Y+
Sbjct: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147
Query: 153 HNNNISVVGSSDF 165
++N +S + F
Sbjct: 148 NHNLLSTISPGAF 160
Score = 42.0 bits (97), Expect = 4e-04
Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P L ++L+ NK++ + L L+NL +L ++ N +S + G+ +L LHL++N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNP 186
L + + ++++ + N I + +F P N + +G++L P
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNF-KPLINLRSLVIAGINLTEIP 228
Score = 33.9 bits (76), Expect = 0.10
Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P+L L + N I R+ + K L NL L ++ +++ + + +L +L + +N+
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 134 LTRVPGGLAEHKYIQVVY--LHNNNISVVGSSDF 165
L +VP +A K + + + L+ N I+ + DF
Sbjct: 248 LIKVP-HVALQKVVNLKFLDLNKNPINRIRRGDF 280
>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 55.5 bits (132), Expect = 3e-08
Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 22/133 (16%)
Query: 54 CPFRCQCHLR-------------VVQCSDLGL-------PPSLTELHLDGNKISRVDAAS 93
CP C C +R V C+DLGL P + L L N I++++ ++
Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGG-LAEHKYIQVVYL 152
+N L L LS N++S+V N ++ P L ++L+ NKLT +P L+E +Q +Y+
Sbjct: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147
Query: 153 HNNNISVVGSSDF 165
++N +S + F
Sbjct: 148 NHNLLSTISPGAF 160
Score = 42.0 bits (97), Expect = 4e-04
Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P L ++L+ NK++ + L L+NL +L ++ N +S + G+ +L LHL++N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNP 186
L + + ++++ + N I + +F P N + +G++L P
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNF-KPLINLRSLVIAGINLTEIP 228
Score = 33.9 bits (76), Expect = 0.10
Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P+L L + N I R+ + K L NL L ++ +++ + + +L +L + +N+
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 134 LTRVPGGLAEHKYIQVVY--LHNNNISVVGSSDF 165
L +VP +A K + + + L+ N I+ + DF
Sbjct: 248 LIKVP-HVALQKVVNLKFLDLNKNPINRIRRGDF 280
>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 55.5 bits (132), Expect = 3e-08
Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 22/133 (16%)
Query: 54 CPFRCQCHLR-------------VVQCSDLGL-------PPSLTELHLDGNKISRVDAAS 93
CP C C +R V C+DLGL P + L L N I++++ ++
Sbjct: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
Query: 94 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGG-LAEHKYIQVVYL 152
+N L L LS N++S+V N ++ P L ++L+ NKLT +P L+E +Q +Y+
Sbjct: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147
Query: 153 HNNNISVVGSSDF 165
++N +S + F
Sbjct: 148 NHNLLSTISPGAF 160
Score = 42.0 bits (97), Expect = 4e-04
Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P L ++L+ NK++ + L L+NL +L ++ N +S + G+ +L LHL++N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNP 186
L + + ++++ + N I + +F P N + +G++L P
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNF-KPLINLRSLVIAGINLTEIP 228
Score = 33.9 bits (76), Expect = 0.10
Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P+L L + N I R+ + K L NL L ++ +++ + + +L +L + +N+
Sbjct: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
Query: 134 LTRVPGGLAEHKYIQVVY--LHNNNISVVGSSDF 165
L +VP +A K + + + L+ N I+ + DF
Sbjct: 248 LIKVP-HVALQKVVNLKFLDLNKNPINRIRRGDF 280
>gi|149773484 leucine rich repeat and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 771
Score = 55.1 bits (131), Expect = 4e-08
Identities = 46/132 (34%), Positives = 62/132 (46%), Gaps = 18/132 (13%)
Query: 49 SLGPVCPFRCQCH----LRVVQCSDLGL---PPSL----TELHLDGNKISRVDAASLKGL 97
S G CP RC C + C+ GL PP++ EL L N I+ V +
Sbjct: 29 SRGQPCPGRCICQNVAPTLTMLCAKTGLLFVPPAIDRRVVELRLTDNFIAAVRRRDFANM 88
Query: 98 NNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG----GLAEHKYIQVVYLH 153
+L L LS N+I V G+ A+ LR LHLD+N+L V G GL +++ L
Sbjct: 89 TSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHL---ILG 145
Query: 154 NNNISVVGSSDF 165
NN I V S+ F
Sbjct: 146 NNQIRRVESAAF 157
Score = 33.5 bits (75), Expect = 0.14
Identities = 22/78 (28%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 75 SLTELHLDGNKISRVDAASLKG-LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
+L L L N+I RV++A+ L+ + L LS+N++ A+ ++ +L L LD+N
Sbjct: 138 NLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNL 197
Query: 134 LTRVPGG--LAEHKYIQV 149
+ + G + HK +++
Sbjct: 198 IDHIAEGTFVQLHKLVRL 215
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 55.1 bits (131), Expect = 4e-08
Identities = 35/125 (28%), Positives = 65/125 (52%), Gaps = 12/125 (9%)
Query: 53 VCPFRCQCHLR----VVQCSDLGL---PPSL----TELHLDGNKISRVDAASLKGLNNLA 101
+CP RC C + C+ GL PP++ EL L N ++ + + +L
Sbjct: 19 ICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLV 78
Query: 102 KLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGL-AEHKYIQVVYLHNNNISVV 160
L LS N+IS + + A+ +LR LHL++N+LT++ + + + + L+NN ++++
Sbjct: 79 DLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLI 138
Query: 161 GSSDF 165
S+ F
Sbjct: 139 SSTAF 143
Score = 38.5 bits (88), Expect = 0.004
Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+L LHL+ N+++++ GL+NL L L+ N ++ + + + + L EL L N L
Sbjct: 100 NLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNL 159
Query: 135 TRVPGGLAEHKYIQVVYLH 153
+P E ++V LH
Sbjct: 160 ETIPWDAVE----KMVSLH 174
Score = 35.0 bits (79), Expect = 0.047
Identities = 17/70 (24%), Positives = 36/70 (51%)
Query: 75 SLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 134
+L L L+ N+++ + + + + L +L LS+N++ + ++ L L LD+N +
Sbjct: 124 NLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMI 183
Query: 135 TRVPGGLAEH 144
+P G H
Sbjct: 184 DNIPKGTFSH 193
>gi|62912472 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 2 [Homo sapiens]
Length = 915
Score = 54.7 bits (130), Expect = 6e-08
Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
PSL L LD N IS V S +GL++L L L N+++ + +L N P L+ + L N+
Sbjct: 86 PSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNR 145
Query: 134 LTRVPGGLAEH-KYIQVVYLHNNNISVVGSSDF 165
++ +P ++ + V++LHNN I +G+ F
Sbjct: 146 ISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 178
Score = 42.7 bits (99), Expect = 2e-04
Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P+L + L N+IS + + + L +L L L N I + S +L L L+ NK
Sbjct: 134 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 193
Query: 134 LTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQY 189
L P + +Q + HNNNI + F + + NP+Q+
Sbjct: 194 LQEFPVAIRTLGRLQELGFHNNNIKAIPEKAF------MGNPLLQTIHFYDNPIQF 243
Score = 37.7 bits (86), Expect = 0.007
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 61 HLRVVQCSDLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 120
H ++ + L L E+ L N+I + A + L++L L LS+N+I ++ + +
Sbjct: 309 HNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFST 368
Query: 121 TPHLRELHLDNNKLTRVP----GGLAEHK 145
L +L L +N+LT +P GGL K
Sbjct: 369 LHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 35.0 bits (79), Expect = 0.047
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 10/128 (7%)
Query: 74 PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNK 133
P L L L+G + + LKG +L L L+ I + +G P LR L L +N+
Sbjct: 253 PKLHTLSLNG-AMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQ 311
Query: 134 LTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQ 193
+ +P L + ++ + L +N I +G+ F ++ +S + L N ++ I
Sbjct: 312 IEELP-SLHRCQKLEEIGLQHNRIWEIGADTF------SQLSSLQALDLSWNAIR--SIH 362
Query: 194 PSTFRCVY 201
P F ++
Sbjct: 363 PEAFSTLH 370
Score = 30.8 bits (68), Expect = 0.89
Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 105 LSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKY-IQVVYLHNNNI 157
LS N+++ + G + L EL L N L+ +PG Y ++++ L NN +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 74
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,760,026
Number of Sequences: 37866
Number of extensions: 390098
Number of successful extensions: 1801
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 805
Number of HSP's gapped (non-prelim): 816
length of query: 212
length of database: 18,247,518
effective HSP length: 98
effective length of query: 114
effective length of database: 14,536,650
effective search space: 1657178100
effective search space used: 1657178100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.