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Search of human proteins with 197313707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens]
(232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens] 457 e-129
gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens] 426 e-120
gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens] 422 e-118
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 61 7e-10
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 55 7e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 54 1e-07
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 54 1e-07
gi|224451082 cytospin A [Homo sapiens] 47 1e-05
gi|224451080 cytospin A [Homo sapiens] 47 1e-05
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 47 1e-05
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 47 1e-05
gi|153945715 myosin VC [Homo sapiens] 46 3e-05
gi|38044112 restin isoform b [Homo sapiens] 45 4e-05
gi|4506751 restin isoform a [Homo sapiens] 45 4e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 45 7e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 45 7e-05
gi|18390344 ATR interacting protein isoform 2 [Homo sapiens] 44 9e-05
gi|18390347 ATR interacting protein isoform 1 [Homo sapiens] 44 9e-05
gi|55956899 keratin 9 [Homo sapiens] 43 2e-04
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 43 2e-04
gi|19743571 TRAF interacting protein TANK isoform b [Homo sapiens] 43 3e-04
gi|19743569 TRAF interacting protein TANK isoform a [Homo sapiens] 43 3e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 43 3e-04
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 43 3e-04
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 43 3e-04
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 43 3e-04
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 43 3e-04
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 43 3e-04
gi|55770834 centromere protein F [Homo sapiens] 43 3e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 42 3e-04
>gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens]
Length = 232
Score = 457 bits (1177), Expect = e-129
Identities = 232/232 (100%), Positives = 232/232 (100%)
Query: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
Query: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQPGVQWRNHGIA 232
KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQPGVQWRNHGIA
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQPGVQWRNHGIA 232
>gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens]
Length = 243
Score = 426 bits (1095), Expect = e-120
Identities = 217/219 (99%), Positives = 218/219 (99%)
Query: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
Query: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSV 219
KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISR S+
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSI 219
>gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens]
Length = 392
Score = 422 bits (1085), Expect = e-118
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS
Sbjct: 1 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 60
Query: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES
Sbjct: 61 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 120
Query: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR
Sbjct: 121 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 180
Query: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS 215
KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS
Sbjct: 181 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS 215
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 61.2 bits (147), Expect = 7e-10
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Query: 1 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE 56
M+++ EDDI IL E D+ S+ GD ASHFAL+TAY DIK+RL E
Sbjct: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 59
Query: 57 KENSLLKKRIRFLEEK--LIARFEEETSSVGREQVNKAYHAYREVCIDR--DNLKSKLDK 112
+EN+ L++R++ E K LI+ F EE E + + +V + + + + +L K
Sbjct: 60 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 119
Query: 113 MNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVM 148
NK+ E L + + + VE L TE+ + +
Sbjct: 120 -NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRAL 154
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 54.7 bits (130), Expect = 7e-08
Identities = 53/214 (24%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Query: 13 NHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEK 72
+ +K ++ + T + + +S+ L EDIK L+ S L++ ++ +
Sbjct: 292 SRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKT 351
Query: 73 LIARFEEETSSVGREQVNKAYHAY--------REVCIDRDNLKSKLDKMNKDNSESLKVL 124
+ EE+ + + E+ NKA A+ VC + L+++ ++ K N + LK+L
Sbjct: 352 ICQLTEEKETQM--EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK-NEDQLKIL 408
Query: 125 NEQLQSKEVELLQL-----RTEVETQQVMRNLNPPSS----NWEVEKLSCDLKIHGLEQE 175
+LQ K EL ++ EVE +++ + L + N + EK++ +LK G EQE
Sbjct: 409 TMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK--GTEQE 466
Query: 176 ----LELMRKECSDLKIELQKAKQTDPYQEDNLK 205
L+ KE DL+I+L ++ Y +K
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVK 500
Score = 42.7 bits (99), Expect = 3e-04
Identities = 48/180 (26%), Positives = 73/180 (40%), Gaps = 30/180 (16%)
Query: 38 HFALVTAYEDI-------KKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVN 90
HF L YE I KK + D EK+ SLL +I E K+ ++ + + E +
Sbjct: 240 HFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKM-----KDLTFLLEESRD 294
Query: 91 KAYHAYREVCIDRDNLKSKLDKMNKDNSE-------------SLKVLNEQLQSKEVELLQ 137
K + + +NLK ++K + E + K L E LQ + Q
Sbjct: 295 KVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQ 354
Query: 138 LRTEVETQQVMRNLNPPSSNW---EVEKLSCDLK--IHGLEQELELMRKECSDLKIELQK 192
L E ETQ N + ++ E E C L+ + +Q LE + L +ELQK
Sbjct: 355 LTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQK 414
Score = 38.5 bits (88), Expect = 0.005
Identities = 39/160 (24%), Positives = 78/160 (48%), Gaps = 19/160 (11%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFE--EETSSVGREQVNKAYHAYREVCIDRD 104
D+ LK+ +++ + KK+ EE+++ + E +ET + R N+ + E+ RD
Sbjct: 536 DMTLELKNQQEDINNNKKQ----EERMLKQIENLQETETQLR---NELEYVREELKQKRD 588
Query: 105 NLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLS 164
+K KLDK + E+ L +Q+++K + +L QQ + L + +
Sbjct: 589 EVKCKLDK----SEENCNNLRKQVENKNKYIEEL------QQENKALKKKGTAESKQLNV 638
Query: 165 CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNL 204
++K++ LE ELE +++ ++ QK + E+NL
Sbjct: 639 YEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENL 678
Score = 29.6 bits (65), Expect = 2.3
Identities = 39/170 (22%), Positives = 74/170 (43%), Gaps = 27/170 (15%)
Query: 33 ESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKA 92
ES F +T + +K ++D + L + + + K+IA +E + +E +
Sbjct: 651 ESAKQKFGEIT--DTYQKEIEDKKISEENLLEEVE--KAKVIA---DEAVKLQKEIDKRC 703
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
H E+ + K + DK+ ++ L + +SKE E LR +E +
Sbjct: 704 QHKIAEMVALMEKHKHQYDKIIEERDSELGLY----KSKEQEQSSLRASLEIEL------ 753
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQED 202
SN + E LS ++++LE+ R+E LK E ++ T ++D
Sbjct: 754 ---SNLKAELLS-------VKKQLEIEREEKEKLKREAKENTATLKEKKD 793
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 53.9 bits (128), Expect = 1e-07
Identities = 52/191 (27%), Positives = 97/191 (50%), Gaps = 21/191 (10%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE---EKLIARFEEETSSVGRE--QVNKAYHAYREVC 100
E+++ L EKEN LL+K+I L+ EK+ A E+E S + RE ++ K +++ +
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLT 686
Query: 101 IDRDNLK---SKLDKMNKD---NSESLKVLNEQLQSKEVELLQLRTEVETQ----QVMRN 150
++L+ S+LD+ N + N ESLK + ++ ++E +L +E E ++++
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746
Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
+ EV D++ L++ LE K+ L+ ELQ D E+ ++L+
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-----DLEMENQTLQKNLE 801
Query: 211 KLSISRVSVAQ 221
+L IS + Q
Sbjct: 802 ELKISSKRLEQ 812
Score = 48.1 bits (113), Expect = 6e-06
Identities = 63/242 (26%), Positives = 105/242 (43%), Gaps = 45/242 (18%)
Query: 6 EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
E I IL E H TV+ + S + A R+KD EKEN +L +
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEA--------------RVKDIEKENKILHES 595
Query: 66 IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNS------E 119
I+ KL ++ E E + Q+ K Y+E + L+++L + K+N
Sbjct: 596 IKETSSKL-SKIEFE-----KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 120 SLKVLNEQLQSKEVELLQLRTE----VETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQE 175
+LK+ E++++ E E +L E +T +NL + E E D E+
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLD------EEN 703
Query: 176 LELMRK----ECSDLKI-ELQ-KAKQTDPYQEDNLKSRDLQKLSI---SRVSVAQPGVQW 226
LEL R +C+ +K+ +LQ + K+ + +E K +L K S R+ V+ G+
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 227 RN 228
N
Sbjct: 764 EN 765
Score = 46.2 bits (108), Expect = 2e-05
Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 21/164 (12%)
Query: 53 KDSEKENSLLKKRIRFLEE---KLIARFEEETSSVGREQVNKAYHAYREVC-IDRDNLKS 108
KD KE + L+K I L E + I E+E E +N+ + R+ I +
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQEN-----EHLNQTVSSLRQRSQISAEARVK 583
Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK 168
++K NK ES+K + +L E E Q++ E+E + E+L +L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK--------EKGERAEELENEL- 634
Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
H LE+E EL++K+ ++LKI +K + + QE++ R+ +KL
Sbjct: 635 -HHLEKENELLQKKITNLKITCEKIEALE--QENSELERENRKL 675
Score = 37.4 bits (85), Expect = 0.011
Identities = 39/177 (22%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS-VGREQVNKAYHAYREVCIDRD 104
E+ ++L D ++E ++ ++ L+++ + + S+ + R++++ A RE + D
Sbjct: 268 EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVD 323
Query: 105 NLKSKLDKMNK--DNSESLKVLNEQLQSKEVELLQLRTEVETQ-QVMRNLNPPSSNWEVE 161
L+S++ + + + E K E+L+ LL+ +T +E Q + R + E E
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVS 218
L K+H +E E ++ RK+ +L E + D + ISR S
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTS 440
Score = 36.2 bits (82), Expect = 0.025
Identities = 46/208 (22%), Positives = 92/208 (44%), Gaps = 16/208 (7%)
Query: 8 DICILNHEKA---HKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE-KENSLLK 63
D I +HEK H+R S+ ++ H L +A+++++ +D E + N LLK
Sbjct: 1154 DSLIKDHEKLELLHERQASEYESL------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1207
Query: 64 KRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV 123
++ + + + + + E+E + + Y+++C + D L ++ K+ +E L+
Sbjct: 1208 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE-TEVLQT 1266
Query: 124 LNEQLQS--KEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRK 181
++ L+S +L Q R E E ++ C+L + L+ LE +
Sbjct: 1267 DHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL-LSQLKGNLEEENR 1325
Query: 182 ECSDLKIELQKAKQTDPYQEDNLKSRDL 209
D L +T E N++S+DL
Sbjct: 1326 HLLDQIQTLMLQNRT--LLEQNMESKDL 1351
Score = 35.8 bits (81), Expect = 0.032
Identities = 40/173 (23%), Positives = 84/173 (48%), Gaps = 28/173 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE--EKLIARFEEETSSVGREQVNKAYHAYREVCIDR 103
+ ++ L+D E EN L+K + L+ K + + E+E S+ +E +++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ----------LEK 829
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKL 163
D K +L+K NK + ++ + L+ V++ L E +T S + K
Sbjct: 830 D--KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL---------SKEIGIYKE 878
Query: 164 SCDLKIHGLEQE-LELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLS 213
SC +++ LE+E EL+++ D+K + L++ ++ + + + DL+KL+
Sbjct: 879 SC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM-NNDLEKLT 929
Score = 34.3 bits (77), Expect = 0.093
Identities = 49/217 (22%), Positives = 84/217 (38%), Gaps = 41/217 (18%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRF-------LEEKLIAR----------FEEETSSVGRE 87
Y++ RLK+ EKEN L KR L E L++ E+ T + +
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Query: 88 QVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVEL-------LQLRT 140
+NK + E D K K+ +SL++ E++ + E L QLR
Sbjct: 936 GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 995
Query: 141 EVET-------------QQVMRNLNPPSS----NWEVEKLSCDLKIHGLEQELELMRKEC 183
E++T ++ M +PP S WE E ++ ++ L + +
Sbjct: 996 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1055
Query: 184 SDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSVA 220
+ L+ E Q K E + Q L++ R +V+
Sbjct: 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVS 1092
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 53.9 bits (128), Expect = 1e-07
Identities = 52/191 (27%), Positives = 97/191 (50%), Gaps = 21/191 (10%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE---EKLIARFEEETSSVGRE--QVNKAYHAYREVC 100
E+++ L EKEN LL+K+I L+ EK+ A E+E S + RE ++ K +++ +
Sbjct: 628 EELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLT 686
Query: 101 IDRDNLK---SKLDKMNKD---NSESLKVLNEQLQSKEVELLQLRTEVETQ----QVMRN 150
++L+ S+LD+ N + N ESLK + ++ ++E +L +E E ++++
Sbjct: 687 FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKA 746
Query: 151 LNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQ 210
+ EV D++ L++ LE K+ L+ ELQ D E+ ++L+
Sbjct: 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-----DLEMENQTLQKNLE 801
Query: 211 KLSISRVSVAQ 221
+L IS + Q
Sbjct: 802 ELKISSKRLEQ 812
Score = 48.1 bits (113), Expect = 6e-06
Identities = 63/242 (26%), Positives = 105/242 (43%), Gaps = 45/242 (18%)
Query: 6 EDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKR 65
E I IL E H TV+ + S + A R+KD EKEN +L +
Sbjct: 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEA--------------RVKDIEKENKILHES 595
Query: 66 IRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNS------E 119
I+ KL ++ E E + Q+ K Y+E + L+++L + K+N
Sbjct: 596 IKETSSKL-SKIEFE-----KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKIT 649
Query: 120 SLKVLNEQLQSKEVELLQLRTE----VETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQE 175
+LK+ E++++ E E +L E +T +NL + E E D E+
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLD------EEN 703
Query: 176 LELMRK----ECSDLKI-ELQ-KAKQTDPYQEDNLKSRDLQKLSI---SRVSVAQPGVQW 226
LEL R +C+ +K+ +LQ + K+ + +E K +L K S R+ V+ G+
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 227 RN 228
N
Sbjct: 764 EN 765
Score = 46.2 bits (108), Expect = 2e-05
Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 21/164 (12%)
Query: 53 KDSEKENSLLKKRIRFLEE---KLIARFEEETSSVGREQVNKAYHAYREVC-IDRDNLKS 108
KD KE + L+K I L E + I E+E E +N+ + R+ I +
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQEN-----EHLNQTVSSLRQRSQISAEARVK 583
Query: 109 KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLK 168
++K NK ES+K + +L E E Q++ E+E + E+L +L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK--------EKGERAEELENEL- 634
Query: 169 IHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
H LE+E EL++K+ ++LKI +K + + QE++ R+ +KL
Sbjct: 635 -HHLEKENELLQKKITNLKITCEKIEALE--QENSELERENRKL 675
Score = 37.4 bits (85), Expect = 0.011
Identities = 39/177 (22%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSS-VGREQVNKAYHAYREVCIDRD 104
E+ ++L D ++E ++ ++ L+++ + + S+ + R++++ A RE + D
Sbjct: 268 EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD----ALREKAVRVD 323
Query: 105 NLKSKLDKMNK--DNSESLKVLNEQLQSKEVELLQLRTEVETQ-QVMRNLNPPSSNWEVE 161
L+S++ + + + E K E+L+ LL+ +T +E Q + R + E E
Sbjct: 324 KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVS 218
L K+H +E E ++ RK+ +L E + D + ISR S
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTS 440
Score = 36.2 bits (82), Expect = 0.025
Identities = 46/208 (22%), Positives = 92/208 (44%), Gaps = 16/208 (7%)
Query: 8 DICILNHEKA---HKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE-KENSLLK 63
D I +HEK H+R S+ ++ H L +A+++++ +D E + N LLK
Sbjct: 1153 DSLIKDHEKLELLHERQASEYESL------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1206
Query: 64 KRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV 123
++ + + + + + E+E + + Y+++C + D L ++ K+ +E L+
Sbjct: 1207 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE-TEVLQT 1265
Query: 124 LNEQLQS--KEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRK 181
++ L+S +L Q R E E ++ C+L + L+ LE +
Sbjct: 1266 DHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL-LSQLKGNLEEENR 1324
Query: 182 ECSDLKIELQKAKQTDPYQEDNLKSRDL 209
D L +T E N++S+DL
Sbjct: 1325 HLLDQIQTLMLQNRT--LLEQNMESKDL 1350
Score = 35.8 bits (81), Expect = 0.032
Identities = 40/173 (23%), Positives = 84/173 (48%), Gaps = 28/173 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE--EKLIARFEEETSSVGREQVNKAYHAYREVCIDR 103
+ ++ L+D E EN L+K + L+ K + + E+E S+ +E +++
Sbjct: 780 QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ----------LEK 829
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKL 163
D K +L+K NK + ++ + L+ V++ L E +T S + K
Sbjct: 830 D--KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL---------SKEIGIYKE 878
Query: 164 SCDLKIHGLEQE-LELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLS 213
SC +++ LE+E EL+++ D+K + L++ ++ + + + DL+KL+
Sbjct: 879 SC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM-NNDLEKLT 929
Score = 34.7 bits (78), Expect = 0.071
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 14/132 (10%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQ-----VNKAYHAYREV 99
Y++ RLK+ EKEN L KR + L+ E+ S + Q + K H ++
Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Query: 100 CIDRDNL----KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVE-----TQQVMRN 150
++++ L +S D+ S+ L + L+ KE ++ L +E QQ+ +
Sbjct: 936 GLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995
Query: 151 LNPPSSNWEVEK 162
L N+E K
Sbjct: 996 LKTVKKNYEALK 1007
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 9/171 (5%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYRE----VCI 101
E+ KK+++D N L+K L+EK R + + + E + + A + +
Sbjct: 656 EEAKKQIEDL---NMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
D +N KL D +K L+ +L+ + E Q + +++T V+ N + E+
Sbjct: 713 DLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIG 772
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
L ++H +++ E + KE ++K Q+ ++ Y N RDL L
Sbjct: 773 DLK--RRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAAL 821
Score = 30.8 bits (68), Expect = 1.0
Identities = 32/160 (20%), Positives = 68/160 (42%), Gaps = 9/160 (5%)
Query: 53 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
K+S L++R R + K + + + + + +++ A D KSK D
Sbjct: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATE---CDVRMSKSKSDN 173
Query: 113 MNKDNSE---SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKI 169
D + +K L ++K+VE+L LR E+ + +N S + + +
Sbjct: 174 QISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMA 233
Query: 170 H---GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
H +E L ++++ + ++ EL + K + +D L +
Sbjct: 234 HQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 9/171 (5%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYRE----VCI 101
E+ KK+++D N L+K L+EK R + + + E + + A + +
Sbjct: 656 EEAKKQIEDL---NMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
D +N KL D +K L+ +L+ + E Q + +++T V+ N + E+
Sbjct: 713 DLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIG 772
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKL 212
L ++H +++ E + KE ++K Q+ ++ Y N RDL L
Sbjct: 773 DLK--RRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAAL 821
Score = 30.8 bits (68), Expect = 1.0
Identities = 32/160 (20%), Positives = 68/160 (42%), Gaps = 9/160 (5%)
Query: 53 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDK 112
K+S L++R R + K + + + + + +++ A D KSK D
Sbjct: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATE---CDVRMSKSKSDN 173
Query: 113 MNKDNSE---SLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKI 169
D + +K L ++K+VE+L LR E+ + +N S + + +
Sbjct: 174 QISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMA 233
Query: 170 H---GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
H +E L ++++ + ++ EL + K + +D L +
Sbjct: 234 HQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 47.0 bits (110), Expect = 1e-05
Identities = 41/168 (24%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDR 103
Y ++ ++D KE +L K+ + L+ +L ++E + +AY A R+ +
Sbjct: 538 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 597
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE-VETQQVMRNLNPPSSNWEVEK 162
D+L L+K+N SE+ K L + L + + QL E + ++ M+ LN
Sbjct: 598 DDLTQALEKLNHVTSET-KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFH 656
Query: 163 LSCDLKIHGLEQELELM--------RKECSDLKIELQKAKQTDPYQED 202
+L++H +++LE M ++ +DLK+ K +Q +QE+
Sbjct: 657 QESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEE 704
Score = 34.3 bits (77), Expect = 0.093
Identities = 42/158 (26%), Positives = 76/158 (48%), Gaps = 28/158 (17%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVG--REQVNKAYHAYREVCIDRD 104
D+ R+K +E +K + LEE L +E T + REQ+ K+ + + + +
Sbjct: 441 DMLDRIKHQHREQGSIKCK---LEEDL----QEATKLLEDKREQLKKSKEHEKLMEGELE 493
Query: 105 NLKS---KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
L+ K DK K+NS L+ NE L++ EL T++E+ +LN +++ +V
Sbjct: 494 ALRQEFKKKDKTLKENSRKLEEENENLRA---ELQCCSTQLES-----SLNKYNTSQQV- 544
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPY 199
I L +E+ L ++ L+ +L KA Q + +
Sbjct: 545 -------IQDLNKEIALQKESLMSLQAQLDKALQKEKH 575
Score = 33.1 bits (74), Expect = 0.21
Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 20/167 (11%)
Query: 42 VTAYEDIKKRLKD-----SEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY 96
V Y+++ K L+ SE++ +++K ++ LE L EE ++ + R+ +
Sbjct: 177 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMK-LELDLHGLREETSAHIERKDKDITILQC 235
Query: 97 R--EVCID---RDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL 151
R E+ ++ L K DK ++ E L+ L ++L + LL+ E+E QQ M
Sbjct: 236 RLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMAT- 294
Query: 152 NPPSSNWEVEKLSCDLK-IHGLEQELELMRKECSDLKIELQKAKQTD 197
E+E + K E E + ++ E LK L++AKQ +
Sbjct: 295 -------ELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQE 334
Score = 27.7 bits (60), Expect = 8.7
Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 22/161 (13%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
ED +++L+ + I+ L+ +L ++E+S +EQ +
Sbjct: 356 EDTQRKLQKGLLLDKQKADTIQELQREL-QMLQKESSMAEKEQTSN-------------- 400
Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
+ ++++++ + SE+L+ L KE LQ +T E M ++ + E+ S
Sbjct: 401 -RKRVEELSLELSEALRKLENS--DKEKRQLQ-KTVAEQDMKMNDMLDRIKHQHREQGSI 456
Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
K LE++L+ K D + +L+K+K+ + E L++
Sbjct: 457 KCK---LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 494
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 47.0 bits (110), Expect = 1e-05
Identities = 41/168 (24%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Query: 45 YEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY-REVCIDR 103
Y ++ ++D KE +L K+ + L+ +L ++E + +AY A R+ +
Sbjct: 683 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 742
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE-VETQQVMRNLNPPSSNWEVEK 162
D+L L+K+N SE+ K L + L + + QL E + ++ M+ LN
Sbjct: 743 DDLTQALEKLNHVTSET-KSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFH 801
Query: 163 LSCDLKIHGLEQELELM--------RKECSDLKIELQKAKQTDPYQED 202
+L++H +++LE M ++ +DLK+ K +Q +QE+
Sbjct: 802 QESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEE 849
Score = 34.3 bits (77), Expect = 0.093
Identities = 42/158 (26%), Positives = 76/158 (48%), Gaps = 28/158 (17%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVG--REQVNKAYHAYREVCIDRD 104
D+ R+K +E +K + LEE L +E T + REQ+ K+ + + + +
Sbjct: 586 DMLDRIKHQHREQGSIKCK---LEEDL----QEATKLLEDKREQLKKSKEHEKLMEGELE 638
Query: 105 NLKS---KLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
L+ K DK K+NS L+ NE L++ EL T++E+ +LN +++ +V
Sbjct: 639 ALRQEFKKKDKTLKENSRKLEEENENLRA---ELQCCSTQLES-----SLNKYNTSQQV- 689
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPY 199
I L +E+ L ++ L+ +L KA Q + +
Sbjct: 690 -------IQDLNKEIALQKESLMSLQAQLDKALQKEKH 720
Score = 33.1 bits (74), Expect = 0.21
Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 20/167 (11%)
Query: 42 VTAYEDIKKRLKD-----SEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAY 96
V Y+++ K L+ SE++ +++K ++ LE L EE ++ + R+ +
Sbjct: 322 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMK-LELDLHGLREETSAHIERKDKDITILQC 380
Query: 97 R--EVCID---RDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL 151
R E+ ++ L K DK ++ E L+ L ++L + LL+ E+E QQ M
Sbjct: 381 RLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMAT- 439
Query: 152 NPPSSNWEVEKLSCDLK-IHGLEQELELMRKECSDLKIELQKAKQTD 197
E+E + K E E + ++ E LK L++AKQ +
Sbjct: 440 -------ELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQE 479
Score = 27.7 bits (60), Expect = 8.7
Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 22/161 (13%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
ED +++L+ + I+ L+ +L ++E+S +EQ +
Sbjct: 501 EDTQRKLQKGLLLDKQKADTIQELQREL-QMLQKESSMAEKEQTSN-------------- 545
Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
+ ++++++ + SE+L+ L KE LQ +T E M ++ + E+ S
Sbjct: 546 -RKRVEELSLELSEALRKLENS--DKEKRQLQ-KTVAEQDMKMNDMLDRIKHQHREQGSI 601
Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS 206
K LE++L+ K D + +L+K+K+ + E L++
Sbjct: 602 KCK---LEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEA 639
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 45.8 bits (107), Expect = 3e-05
Identities = 43/171 (25%), Positives = 82/171 (47%), Gaps = 17/171 (9%)
Query: 48 IKKRLKDSEKENSLLKKRIRFL------EEKLIARFEEETSSVGREQVNKAYHAYREVCI 101
++K+L+D KEN L +++ L + + I + E E + N R
Sbjct: 894 LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY--- 950
Query: 102 DRDNLKSKLDKMNKDNSESLKVLNEQLQSK---EVELLQLRTEVETQQVMRNLNPPSSNW 158
RD ++ KL K+ K NSE L+ EQ+Q K + E L+ + + T+Q+ ++
Sbjct: 951 -RDAVEEKLAKLQKHNSE-LETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQR 1008
Query: 159 EVEKLSCDLKIHGLEQELELMRKE---CSDLKIELQKAKQTDPYQEDNLKS 206
+ + S +LK E++++ +++E D K++LQ + + D LK+
Sbjct: 1009 MLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKA 1059
Score = 34.3 bits (77), Expect = 0.093
Identities = 28/150 (18%), Positives = 68/150 (45%), Gaps = 18/150 (12%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
D K+++ + EK+ L+ R+ EK+ + EE ++ + R Q +
Sbjct: 1213 DFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQE------------EEGTQ 1260
Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCD 166
+ L+ N+ +++ + L +++Q + L+ + ET+ ++ N+ E
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVK------CNFRQEASRLT 1314
Query: 167 LKIHGLEQELELMRKECSDLKIELQKAKQT 196
L+ LE+EL++ + L+ +++ +T
Sbjct: 1315 LENRDLEEELDMKDRVIKKLQDQVKTLSKT 1344
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 45.4 bits (106), Expect = 4e-05
Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 31/186 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLI---ARFEEETSSVGREQVNKAYHAYREVCID 102
++ +L E++ ++L + L E L A+F E+ EQ+ KA
Sbjct: 829 QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER--EEQLIKAKEKL------ 880
Query: 103 RDNLKSKLDKMNKDNSESLKVLNEQLQSKE--VELLQLRT--------------EVETQQ 146
+N +++ KM+ DNS L +N++L+ KE VE LQL+ E T +
Sbjct: 881 -ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939
Query: 147 VMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKA-KQTDPYQEDNLK 205
++ + E EK + K+ LE+++E +C +LK ++A +T E+ L
Sbjct: 940 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL- 998
Query: 206 SRDLQK 211
++LQK
Sbjct: 999 -QNLQK 1003
Score = 35.0 bits (79), Expect = 0.055
Identities = 52/203 (25%), Positives = 96/203 (47%), Gaps = 42/203 (20%)
Query: 32 DESVASHFALVTAYEDIK----KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGRE 87
+ ++ASH A E++K K L E + LK +I EK+ ++ E ++ +
Sbjct: 582 ETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI----EKMRLDYQHEIENLQNQ 634
Query: 88 QVN-KAYHAYR---------EVCIDRDN----LKSKLDKMNKDN----SESLKVLNE-QL 128
Q + +A HA +V +++N ++SKLDK + ++L L E ++
Sbjct: 635 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 694
Query: 129 QSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI 188
+ KE+E+LQ + +T +V+ N E EKL +L+ +RK S+ K
Sbjct: 695 KVKELEVLQAKCNEQT-KVIDNFTSQLKATE-EKL----------LDLDALRKASSEGKS 742
Query: 189 ELQKAKQTDPYQEDNLKSRDLQK 211
E++K +Q E +K +++K
Sbjct: 743 EMKKLRQQLEAAEKQIKHLEIEK 765
Score = 34.7 bits (78), Expect = 0.071
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)
Query: 63 KKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK 122
++ I L+E AR EET ++++ Y A ++ + ++LKSKL+ NK+NS+ +
Sbjct: 521 QREITSLKEHFGAR--EETH---QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 575
Query: 123 VLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNW-----EVEKLSCDL--KIHGLEQE 175
+ +L++ Q E++ + L ++ + ++EK+ D +I L+ +
Sbjct: 576 LWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ 634
Query: 176 LELMR----KECSDLKIELQK 192
+ R KE L+ +L K
Sbjct: 635 QDSERAAHAKEMEALRAKLMK 655
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 45.4 bits (106), Expect = 4e-05
Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 31/186 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLI---ARFEEETSSVGREQVNKAYHAYREVCID 102
++ +L E++ ++L + L E L A+F E+ EQ+ KA
Sbjct: 864 QETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER--EEQLIKAKEKL------ 915
Query: 103 RDNLKSKLDKMNKDNSESLKVLNEQLQSKE--VELLQLRT--------------EVETQQ 146
+N +++ KM+ DNS L +N++L+ KE VE LQL+ E T +
Sbjct: 916 -ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974
Query: 147 VMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKA-KQTDPYQEDNLK 205
++ + E EK + K+ LE+++E +C +LK ++A +T E+ L
Sbjct: 975 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL- 1033
Query: 206 SRDLQK 211
++LQK
Sbjct: 1034 -QNLQK 1038
Score = 35.0 bits (79), Expect = 0.055
Identities = 52/203 (25%), Positives = 96/203 (47%), Gaps = 42/203 (20%)
Query: 32 DESVASHFALVTAYEDIK----KRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGRE 87
+ ++ASH A E++K K L E + LK +I EK+ ++ E ++ +
Sbjct: 617 ETAIASH---QQAMEELKVSFSKGLGTETAEFAELKTQI----EKMRLDYQHEIENLQNQ 669
Query: 88 QVN-KAYHAYR---------EVCIDRDN----LKSKLDKMNKDN----SESLKVLNE-QL 128
Q + +A HA +V +++N ++SKLDK + ++L L E ++
Sbjct: 670 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 729
Query: 129 QSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKI 188
+ KE+E+LQ + +T +V+ N E EKL +L+ +RK S+ K
Sbjct: 730 KVKELEVLQAKCNEQT-KVIDNFTSQLKATE-EKL----------LDLDALRKASSEGKS 777
Query: 189 ELQKAKQTDPYQEDNLKSRDLQK 211
E++K +Q E +K +++K
Sbjct: 778 EMKKLRQQLEAAEKQIKHLEIEK 800
Score = 34.7 bits (78), Expect = 0.071
Identities = 34/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)
Query: 63 KKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK 122
++ I L+E AR EET ++++ Y A ++ + ++LKSKL+ NK+NS+ +
Sbjct: 556 QREITSLKEHFGAR--EETH---QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIA 610
Query: 123 VLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNW-----EVEKLSCDL--KIHGLEQE 175
+ +L++ Q E++ + L ++ + ++EK+ D +I L+ +
Sbjct: 611 LWKSKLETAIASHQQAMEELKV-SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ 669
Query: 176 LELMR----KECSDLKIELQK 192
+ R KE L+ +L K
Sbjct: 670 QDSERAAHAKEMEALRAKLMK 690
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 44.7 bits (104), Expect = 7e-05
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 34/163 (20%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE-------------EKLIARFEEETSSVGREQVNKA 92
E+++++L+D EK+ S LK+R++ L+ E+ +A +E T +EQ ++
Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE-KERTIERLKEQRDRD 639
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
+E + DN K L KD E + +L L KE LL L+
Sbjct: 640 EREKQE---EIDNYKKDL----KDLKEKVSLLQGDLSEKEASLLDLKEH----------- 681
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQ 195
+S+ L D ++ LE LE ++EC ++ +L+KA +
Sbjct: 682 --ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 722
Score = 36.6 bits (83), Expect = 0.019
Identities = 39/170 (22%), Positives = 81/170 (47%), Gaps = 23/170 (13%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
D++ +LK+ +EN LL+K + E KL +SS+ + + +E + +D
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKL-------SSSMNSIKTFWSPELKKERALRKDE- 204
Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL-NPPSSNWEVEKLSC 165
SK+ E +V+ E+ Q ++ + L+ E+ Q+ + L SS+ E
Sbjct: 205 ASKITIW----KEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVA 260
Query: 166 DL------KIHGLEQ----ELELMRKECSDLKIELQKAKQTDPYQEDNLK 205
+L ++H + EL L+RK ++++ ++ KQT +++++K
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 310
Score = 33.1 bits (74), Expect = 0.21
Identities = 43/176 (24%), Positives = 78/176 (44%), Gaps = 30/176 (17%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
E +K+ L E + LKK+ L+ + I + ++E S E +
Sbjct: 441 EQLKEELSSKEAQWEELKKKAAGLQAE-IGQVKQELSRKDTELLA--------------- 484
Query: 106 LKSKLDKMNK---DNSESLKVLNEQLQSKEVELLQLRTEV--------ETQQVMRNLNPP 154
L++KL+ + D+ + ++VL E L +KE L+TEV E + ++
Sbjct: 485 LQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQ 544
Query: 155 SSNWEVEKLSCDLKIHGLEQELELMRKECSDL--KIE-LQKAKQTDPYQEDNLKSR 207
+ EK + +IH L+ L++ ++ + L KIE LQ+ + Q +LK R
Sbjct: 545 IQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER 600
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 44.7 bits (104), Expect = 7e-05
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 34/163 (20%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLE-------------EKLIARFEEETSSVGREQVNKA 92
E+++++L+D EK+ S LK+R++ L+ E+ +A +E T +EQ ++
Sbjct: 553 ENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAE-KERTIERLKEQRDRD 611
Query: 93 YHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLN 152
+E + DN K L KD E + +L L KE LL L+
Sbjct: 612 EREKQE---EIDNYKKDL----KDLKEKVSLLQGDLSEKEASLLDLKEH----------- 653
Query: 153 PPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQ 195
+S+ L D ++ LE LE ++EC ++ +L+KA +
Sbjct: 654 --ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHE 694
Score = 36.6 bits (83), Expect = 0.019
Identities = 39/170 (22%), Positives = 81/170 (47%), Gaps = 23/170 (13%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
D++ +LK+ +EN LL+K + E KL +SS+ + + +E + +D
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKL-------SSSMNSIKTFWSPELKKERALRKDE- 204
Query: 107 KSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL-NPPSSNWEVEKLSC 165
SK+ E +V+ E+ Q ++ + L+ E+ Q+ + L SS+ E
Sbjct: 205 ASKITIW----KEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVA 260
Query: 166 DL------KIHGLEQ----ELELMRKECSDLKIELQKAKQTDPYQEDNLK 205
+L ++H + EL L+RK ++++ ++ KQT +++++K
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 310
Score = 32.3 bits (72), Expect = 0.35
Identities = 49/219 (22%), Positives = 92/219 (42%), Gaps = 34/219 (15%)
Query: 15 EKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLI 74
E+ H+R P S A AL T E ++ E+ L++ I+ L+
Sbjct: 362 EEMHRRFENAPDS--------AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGA 413
Query: 75 ARFEEETSSVGREQVNKAYHAYREVCIDRDN------------LKSKLDKMNK---DNSE 119
EE + + +V +++ + + I + L++KL+ + D+ +
Sbjct: 414 LSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQ 473
Query: 120 SLKVLNEQLQSKEVELLQLRTEV--------ETQQVMRNLNPPSSNWEVEKLSCDLKIHG 171
++VL E L +KE L+TEV E + ++ + EK + +IH
Sbjct: 474 HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD 533
Query: 172 LEQELELMRKECSDL--KIE-LQKAKQTDPYQEDNLKSR 207
L+ L++ ++ + L KIE LQ+ + Q +LK R
Sbjct: 534 LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER 572
>gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]
Length = 764
Score = 44.3 bits (103), Expect = 9e-05
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 12/115 (10%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
L Y+++K+++K E+E + I+ L + L +T SV EQ +
Sbjct: 117 LQAQYKELKEKMKVMEEEVLIKNGEIKILRDSL-----HQTESVLEEQRRSHF------L 165
Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPS 155
++++ ++ DK K+ S+ L+ L +LQ K+ E+ +LRT+++T + L PS
Sbjct: 166 LEQEKTQALSDK-EKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPS 219
>gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]
Length = 791
Score = 44.3 bits (103), Expect = 9e-05
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 12/115 (10%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
L Y+++K+++K E+E + I+ L + L +T SV EQ +
Sbjct: 117 LQAQYKELKEKMKVMEEEVLIKNGEIKILRDSL-----HQTESVLEEQRRSHF------L 165
Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPS 155
++++ ++ DK K+ S+ L+ L +LQ K+ E+ +LRT+++T + L PS
Sbjct: 166 LEQEKTQALSDK-EKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPS 219
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 43.1 bits (100), Expect = 2e-04
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 20/148 (13%)
Query: 15 EKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLL----KKRIRFLE 70
+K HK + SGD +V + V +D+ K L D +E L +K I
Sbjct: 289 KKNHKEEMSQLTGQNSGDVNVEIN---VAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQY 345
Query: 71 EKLIARFEEETSSVGRE------QVNKAYHAYREVCIDRDNLKSK---LDKMNKDNSE-- 119
E I + E E SS G+E +V + H +E+ I+ + SK L+K +D
Sbjct: 346 ETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRY 405
Query: 120 --SLKVLNEQLQSKEVELLQLRTEVETQ 145
L+++ EQ+ + E ++ +R E+E Q
Sbjct: 406 CGQLQMIQEQISNLEAQITDVRQEIECQ 433
Score = 27.7 bits (60), Expect = 8.7
Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 24/150 (16%)
Query: 46 EDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDN 105
+++ RL + L++ LE K+ ++++ G + K Y Y D+
Sbjct: 158 QELNSRLASYLDKVQALEEANNDLENKIQDWYDKK----GPAAIQKNYSPYYNTI---DD 210
Query: 106 LKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
LK ++ + N+++L + + + L R + E +Q +R
Sbjct: 211 LKDQIVDLTVGNNKTLL----DIDNTRMTLDDFRIKFEMEQNLRQ-------------GV 253
Query: 166 DLKIHGLEQELELMRKECSDLKIELQKAKQ 195
D I+GL Q L+ + E SDL+++ + ++
Sbjct: 254 DADINGLRQVLDNLTMEKSDLEMQYETLQE 283
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 43.1 bits (100), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 16/187 (8%)
Query: 38 HFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
H + A+E KK + KE +R+ EK +F+E+ ++ Q + +
Sbjct: 745 HEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHH 804
Query: 98 EVCIDR--DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVE--TQQVMRNLNP 153
+DR K ++ K N E+LK L Q+ + +++ QL + +E ++++ +LN
Sbjct: 805 LESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQ 864
Query: 154 PSSNWEVEKLSCDLK-----IHGLEQELELMR---KECSDLKIELQKA--KQTDPYQEDN 203
N EK LK ++ L++EL++ +E S+ + LQ +Q Q++
Sbjct: 865 LEGN--KEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQET 922
Query: 204 LKSRDLQ 210
+++ +L+
Sbjct: 923 IRNGELE 929
Score = 34.3 bits (77), Expect = 0.093
Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 19/172 (11%)
Query: 54 DSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCI----DRDNLKSK 109
+ +KEN + ++ L+ ++ EET V Q++ A +E + + K K
Sbjct: 818 EMKKENMKKDEALKALQNQV----SEETIKV--RQLDSALEICKEELVLHLNQLEGNKEK 871
Query: 110 LDKMNKDNSES-------LKVLNEQLQ-SKEVELLQLRTEVETQQVMRNLNPPSSNWEVE 161
+K K SE LK+ N LQ + E ++ T + QQ+++ + E
Sbjct: 872 FEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDT 931
Query: 162 KLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLS 213
+ + ++ LEQEL+ R E S K+ + K E +LK + + +L+
Sbjct: 932 QTKLEKQVSKLEQELQKQR-ESSAEKLRKMEEKCESAAHEADLKRQKVIELT 982
Score = 33.5 bits (75), Expect = 0.16
Identities = 44/176 (25%), Positives = 70/176 (39%), Gaps = 35/176 (19%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVC 100
LVT E+++ +L E ENS LK V + +E
Sbjct: 639 LVTGIEELRTKLIQIEAENSDLK--------------------VNMAHRTSQFQLIQEEL 678
Query: 101 IDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTE--------VETQQVMRNLN 152
+++ + SKL+ L L +QL+ K V + + +E + +R+L
Sbjct: 679 LEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLE 738
Query: 153 PPSSNWEVEKLSCDL----KIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNL 204
+ N E EK+ KIH LEQ E M K+ L+ +L+K Q QE +
Sbjct: 739 -TNINTEHEKICLAFEKAKKIH-LEQHKE-MEKQIERLEAQLEKKDQQFKEQEKTM 791
Score = 30.8 bits (68), Expect = 1.0
Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 6/112 (5%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRI---RFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
L + ED+K+ K+ + + L + + + E L AR + E + E V AY
Sbjct: 1286 LSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAE-VESLKEAYH 1344
Query: 98 EVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVET--QQV 147
I +K S++ LNEQL+ ++EL + + V QQV
Sbjct: 1345 MEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQV 1396
>gi|19743571 TRAF interacting protein TANK isoform b [Homo sapiens]
Length = 119
Score = 42.7 bits (99), Expect = 3e-04
Identities = 17/56 (30%), Positives = 37/56 (66%)
Query: 87 EQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEV 142
EQ+NKAY A+R+ C+DRD+ +L + ++ + ++ EQL ++ + +L++++
Sbjct: 7 EQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQL 62
>gi|19743569 TRAF interacting protein TANK isoform a [Homo sapiens]
Length = 425
Score = 42.7 bits (99), Expect = 3e-04
Identities = 17/56 (30%), Positives = 37/56 (66%)
Query: 87 EQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEV 142
EQ+NKAY A+R+ C+DRD+ +L + ++ + ++ EQL ++ + +L++++
Sbjct: 7 EQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQL 62
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 502 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 556
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 557 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 616
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 617 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 676
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
+ E EKL ++ E L M+ + S + EL + KQ Q++N
Sbjct: 677 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 729
Score = 37.0 bits (84), Expect = 0.014
Identities = 50/230 (21%), Positives = 102/230 (44%), Gaps = 29/230 (12%)
Query: 14 HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
HEK + V+ + S ++ V K+L D++KENS+ L
Sbjct: 684 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 743
Query: 63 KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
+ + +EEK+ +A E E + + +Q+ + A + + R + + + +
Sbjct: 744 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 802
Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
S L E ++ KE E++Q+R+EV QV R N + S + +++ L
Sbjct: 803 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 856
Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQ 221
Q+ + ++E +++K E + D ++ N S+++ KL + S++Q
Sbjct: 857 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 906
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 491 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 545
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 546 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 605
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 606 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 665
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
+ E EKL ++ E L M+ + S + EL + KQ Q++N
Sbjct: 666 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 718
Score = 37.0 bits (84), Expect = 0.014
Identities = 50/230 (21%), Positives = 102/230 (44%), Gaps = 29/230 (12%)
Query: 14 HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
HEK + V+ + S ++ V K+L D++KENS+ L
Sbjct: 673 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 732
Query: 63 KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
+ + +EEK+ +A E E + + +Q+ + A + + R + + + +
Sbjct: 733 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 791
Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
S L E ++ KE E++Q+R+EV QV R N + S + +++ L
Sbjct: 792 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 845
Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQ 221
Q+ + ++E +++K E + D ++ N S+++ KL + S++Q
Sbjct: 846 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 895
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 470 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 524
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 525 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 584
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 585 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 644
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
+ E EKL ++ E L M+ + S + EL + KQ Q++N
Sbjct: 645 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 697
Score = 37.0 bits (84), Expect = 0.014
Identities = 50/230 (21%), Positives = 102/230 (44%), Gaps = 29/230 (12%)
Query: 14 HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
HEK + V+ + S ++ V K+L D++KENS+ L
Sbjct: 652 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 711
Query: 63 KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
+ + +EEK+ +A E E + + +Q+ + A + + R + + + +
Sbjct: 712 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 770
Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
S L E ++ KE E++Q+R+EV QV R N + S + +++ L
Sbjct: 771 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 824
Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQ 221
Q+ + ++E +++K E + D ++ N S+++ KL + S++Q
Sbjct: 825 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 874
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
+ E EKL ++ E L M+ + S + EL + KQ Q++N
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726
Score = 37.0 bits (84), Expect = 0.014
Identities = 50/230 (21%), Positives = 102/230 (44%), Gaps = 29/230 (12%)
Query: 14 HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
HEK + V+ + S ++ V K+L D++KENS+ L
Sbjct: 681 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 740
Query: 63 KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
+ + +EEK+ +A E E + + +Q+ + A + + R + + + +
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 799
Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
S L E ++ KE E++Q+R+EV QV R N + S + +++ L
Sbjct: 800 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 853
Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQ 221
Q+ + ++E +++K E + D ++ N S+++ KL + S++Q
Sbjct: 854 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 903
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
+ E EKL ++ E L M+ + S + EL + KQ Q++N
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726
Score = 37.0 bits (84), Expect = 0.014
Identities = 50/230 (21%), Positives = 102/230 (44%), Gaps = 29/230 (12%)
Query: 14 HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
HEK + V+ + S ++ V K+L D++KENS+ L
Sbjct: 681 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 740
Query: 63 KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
+ + +EEK+ +A E E + + +Q+ + A + + R + + + +
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 799
Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
S L E ++ KE E++Q+R+EV QV R N + S + +++ L
Sbjct: 800 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 853
Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQ 221
Q+ + ++E +++K E + D ++ N S+++ KL + S++Q
Sbjct: 854 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 903
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.7 bits (99), Expect = 3e-04
Identities = 58/233 (24%), Positives = 108/233 (46%), Gaps = 45/233 (19%)
Query: 11 ILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYED----IKKRLKDSEKENSLLKKRI 66
+L+ +K K V+P S+ + SHF + E+ +K+ L+++ +E+ K+++
Sbjct: 499 VLSVQKQMKLGLVSPESMDN-----YSHFHELRVTEEEINVLKQDLQNALEESERNKEKV 553
Query: 67 RFLEEKLIAR------------FEEETSS-------VGREQV---NKAYHAYREVCIDRD 104
R LEEKL+ R +EE SS + +E+ K A E+ +D
Sbjct: 554 RELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 105 NLKSKLDKMNKDNSESLKV----LNEQLQSKEVELLQL----RTEVETQQVMRNLNPPSS 156
LKS++ + D +E +K + ++L + EL QL + E+E + ++L ++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 157 NW----EVEKLS--CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDN 203
+ E EKL ++ E L M+ + S + EL + KQ Q++N
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726
Score = 37.0 bits (84), Expect = 0.014
Identities = 50/230 (21%), Positives = 102/230 (44%), Gaps = 29/230 (12%)
Query: 14 HEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSL-----------L 62
HEK + V+ + S ++ V K+L D++KENS+ L
Sbjct: 681 HEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTL 740
Query: 63 KKRIRFLEEKL------IARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKD 116
+ + +EEK+ +A E E + + +Q+ + A + + R + + + +
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKL-EKQLLEEKAAMTDAMVPRSSYEKLQSSLESE 799
Query: 117 NSESLKVLNEQLQSKE---VELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLE 173
S L E ++ KE E++Q+R+EV QV R N + S + +++ L
Sbjct: 800 VSVLASKLKESVKEKEKVHSEVVQIRSEV--SQVKRE----KENIQTLLKSKEQEVNELL 853
Query: 174 QELELMRKECSDLK--IELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQ 221
Q+ + ++E +++K E + D ++ N S+++ KL + S++Q
Sbjct: 854 QKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 903
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 42.7 bits (99), Expect = 3e-04
Identities = 45/175 (25%), Positives = 83/175 (47%), Gaps = 29/175 (16%)
Query: 48 IKKRLKDSEKENSLLKKRIRFLEEKL-IARFEEETSSVGRE-----------QVNKAYHA 95
+ ++LK+SE LLK R+ LE +L IAR +E +++ E ++ +
Sbjct: 2320 VLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQS 2379
Query: 96 YREVCID-------RDNLKSKLDKMNKDNSESLKVLNEQ----LQSKEVELLQLRTEVET 144
R + +D ++NL ++L K + SE L+++N LQ KE E +Q++ + T
Sbjct: 2380 LRGLELDVVTIRSEKENLTNELQKEQERISE-LEIINSSFENILQEKEQEKVQMKEKSST 2438
Query: 145 -----QQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAK 194
Q ++ LN + ++ +C K L ++E + E + L L +AK
Sbjct: 2439 AMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAK 2493
Score = 40.0 bits (92), Expect = 0.002
Identities = 41/197 (20%), Positives = 84/197 (42%), Gaps = 38/197 (19%)
Query: 53 KDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLD- 111
+D E L+ ++ + L+ + + S + +Q +H++ + ++ ++ S+
Sbjct: 754 QDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSE 813
Query: 112 -KMNKDNS------------------ESLKVLNEQLQSKEVELLQLRTEVETQ----QVM 148
++ D S ES K +N LQ + EL+Q++ E+E + M
Sbjct: 814 CRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQM 873
Query: 149 RNLNPPSSNWEVEKLSCDLKIH------------GLEQELELMRKECSDLKIELQKAKQT 196
++ + KL D H E+EL+L+ + + E+Q+ K++
Sbjct: 874 HQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKS 933
Query: 197 DPYQEDNLKSRDLQKLS 213
+ ED+LK +LQ LS
Sbjct: 934 NHLLEDSLK--ELQLLS 948
Score = 37.4 bits (85), Expect = 0.011
Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 32/149 (21%)
Query: 48 IKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLK 107
I ++LK+ E+EN LK ++ LE +L + EE + V +D +N K
Sbjct: 2138 IAEKLKERERENDSLKDKVENLEREL--QMSEENQEL--------------VILDAENSK 2181
Query: 108 SKLDKMN---KDNSESLKVLNEQLQSKEVELLQLRTEVE--TQQVMRNLNPPSSNWEVEK 162
++++ + ++ + SLKV E++L+ LR+E E T+Q+ S E++K
Sbjct: 2182 AEVETLKTQIEEMARSLKVF-------ELDLVTLRSEKENLTKQIQEKQGQLS---ELDK 2231
Query: 163 LSCDLK-IHGLEQELELMRKECSDLKIEL 190
L K + +++ E+ KE S +E+
Sbjct: 2232 LLSSFKSLLEEKEQAEIQIKEESKTAVEM 2260
Score = 36.2 bits (82), Expect = 0.025
Identities = 42/177 (23%), Positives = 83/177 (46%), Gaps = 24/177 (13%)
Query: 41 LVTAYEDIKKRLKDSE---KENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYR 97
L+++++ + + + +E KE S K + L+ +L E + G +++ KA
Sbjct: 2232 LLSSFKSLLEEKEQAEIQIKEES--KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSL 2289
Query: 98 EVCIDRDN-LKSKLDKMNK----DNSESLKVLNEQLQSKE--------VELLQLRTEV-E 143
+ I+ ++ L++ ++K+ D + L VL + +S+ VE L+ E+
Sbjct: 2290 DPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIAR 2349
Query: 144 TQQVMRNLNPPSSNWEVEKLSCDLK-----IHGLEQELELMRKECSDLKIELQKAKQ 195
T Q L +S EVE L ++ + GLE ++ +R E +L ELQK ++
Sbjct: 2350 TNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQE 2406
Score = 35.8 bits (81), Expect = 0.032
Identities = 42/171 (24%), Positives = 78/171 (45%), Gaps = 17/171 (9%)
Query: 56 EKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNK 115
E+E S+ + ++ +EKLI E + E +++ Y A +E + L ++ + +
Sbjct: 1006 EREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCE 1065
Query: 116 DNSESLKVLNEQLQSKEVELL-----------QLRTEVET-QQVMRN-LNPPSSNWEVEK 162
+ L+ L E + E L L E+ET QQ +R+ + +N + E
Sbjct: 1066 NRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEA 1125
Query: 163 LSCDLKIHGLEQELELMRKECSDLKIE---LQKAKQTDPYQEDNLKSRDLQ 210
+I L++E M+KE +DL E L K +T ++ NL+S ++
Sbjct: 1126 GGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKT-KHECQNLESEPIR 1175
Score = 34.7 bits (78), Expect = 0.071
Identities = 46/261 (17%), Positives = 117/261 (44%), Gaps = 47/261 (18%)
Query: 5 VEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKK 64
+E D+ + EK + + + E ++ + +++E+I L++ E+E +K+
Sbjct: 2383 LELDVVTIRSEKENLTN-----ELQKEQERISELEIINSSFENI---LQEKEQEKVQMKE 2434
Query: 65 RIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRD-NLKSKLDKMNKDNSESLKV 123
+ E L + +E V A H +E C ++ NL S+++ + + ++ L+
Sbjct: 2435 KSSTAMEMLQTQLKELNERVA------ALHNDQEACKAKEQNLSSQVECLELEKAQLLQG 2488
Query: 124 LNE------------------------QLQSKEVELLQLRTEVETQ-QVMRNLNPPSSN- 157
L+E +L+ K+ E+ +L+ +++ Q Q++ L+
Sbjct: 2489 LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEH 2548
Query: 158 --WEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLS-- 213
W+ + L LEQ++++++ + + L+ L+ + + E+ L+ + K+S
Sbjct: 2549 QLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFV 2608
Query: 214 --ISRVSVAQPGVQWRNHGIA 232
+++++ + +Q H +A
Sbjct: 2609 EKVNKMTAKETELQREMHEMA 2629
Score = 33.1 bits (74), Expect = 0.21
Identities = 48/225 (21%), Positives = 87/225 (38%), Gaps = 53/225 (23%)
Query: 44 AYEDIKKRLKDSEKENSLL--------------KKRIRFLEEKLIAR---------FEEE 80
AYED+ ++ K ++++NS L K + L+E F EE
Sbjct: 1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEE 1094
Query: 81 TSSVGREQVNKAYHAYREVCIDRDN---------------LKSKLDKMNK-------DNS 118
+ ++ A R D N LK + +KM K +N
Sbjct: 1095 RNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENE 1154
Query: 119 ESLKVLNEQLQSKEVELLQLRTEVETQQVMRNL--NPPSSNWEVEKLSCD------LKIH 170
+ +KV+ + + + +E +R V+ ++ RN P + EV+++S D +++
Sbjct: 1155 QLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLE 1214
Query: 171 GLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS 215
+ + EL +E K LQ QT + +D+Q IS
Sbjct: 1215 AMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEIS 1259
Score = 31.6 bits (70), Expect = 0.60
Identities = 38/177 (21%), Positives = 74/177 (41%), Gaps = 25/177 (14%)
Query: 41 LVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQV----------- 89
L+ + K +LK+ ENS LKK + + + + + + + Q+
Sbjct: 2653 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2712
Query: 90 -----NKAYHAYREVCIDRDNLKSKLDKMNKDNSE------SLKVLNEQLQSKEVELLQL 138
NK Y E+ R+ L SK + ++ E S + LN L++ L +L
Sbjct: 2713 LLLDTNKQYEV--EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2770
Query: 139 R-TEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAK 194
+ T+++ + + L + + + LE+E E+++KE S L+ +K K
Sbjct: 2771 KKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQK 2827
Score = 31.2 bits (69), Expect = 0.79
Identities = 37/186 (19%), Positives = 78/186 (41%), Gaps = 26/186 (13%)
Query: 23 VTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETS 82
+TP YSG + YED+K++ +E L+ ++ L+ K ++ + +
Sbjct: 153 LTPSQYYSGSK-----------YEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQAT 201
Query: 83 ----SVGREQVNKAYHAYR-EVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQ 137
+ R Q + + +++ E + S+ + +D S S EQ + LQ
Sbjct: 202 MNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASY-FSGEQEVTPSRSTLQ 260
Query: 138 LRTEVETQQVMRNLNPP-------SSNWEVEKL--SCDLKIHGLEQELELMRKECSDLKI 188
+ N + P + N E+ +L++ G E+E++ + +L++
Sbjct: 261 IGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQL 320
Query: 189 ELQKAK 194
+L+KAK
Sbjct: 321 QLEKAK 326
Score = 31.2 bits (69), Expect = 0.79
Identities = 46/181 (25%), Positives = 77/181 (42%), Gaps = 25/181 (13%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEK---LIARFEEETSSVGREQVNKAYHAYREVCIDR 103
+++ R+K++ EN L I + K L+ +E S + ++V E CI+
Sbjct: 1771 NLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKI--EACIEL 1828
Query: 104 DNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRN---LNPPSSNWE- 159
+ + +L K N D SE L E ELLQ VET + + + ++ S+ E
Sbjct: 1829 EKIVGELKKENSDLSEKL----EYFSCDHQELLQ---RVETSEGLNSDLEMHADKSSRED 1881
Query: 160 ----VEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSIS 215
V K++ K L+ E EL R IE + Y E +L+ +KL +
Sbjct: 1882 IGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEAL-----YLEADLEVVQTEKLCLE 1936
Query: 216 R 216
+
Sbjct: 1937 K 1937
Score = 30.0 bits (66), Expect = 1.8
Identities = 38/171 (22%), Positives = 74/171 (43%), Gaps = 18/171 (10%)
Query: 57 KENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDR-DNLKSKLDKMNK 115
K N K+R +E +L +R E +S+ E + Y E ++ K L+K N+
Sbjct: 1888 KVNDSWKERFLDVENEL-SRIRSEKASIEHEAL------YLEADLEVVQTEKLCLEKDNE 1940
Query: 116 DNSESLKVLNEQLQSKEVELLQLRTEVET--------QQVMRNLNPPSSNWEVEKLSCDL 167
+ + + L E+L E QLR E++T Q+ + + E + C
Sbjct: 1941 NKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLH 2000
Query: 168 KIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKS--RDLQKLSISR 216
I E E++ + L ++ + + + ++ L+S +D Q LS+++
Sbjct: 2001 CIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTK 2051
Score = 28.9 bits (63), Expect = 3.9
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 5/144 (3%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNL 106
++++ +++ +KEN+LLK + + + E E ++ ++ +N++ + E+ +
Sbjct: 476 ELRRSMEEMKKENNLLKSHSE-QKAREVCHLEAELKNI-KQCLNQSQNFAEEMKAKNTSQ 533
Query: 107 KSKL-DKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSC 165
++ L D K N + + E+L+ +L + R + R + N ++ K
Sbjct: 534 ETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Query: 166 DLKIHGLEQELELMRKECSDLKIE 189
+ K L LEL +KE +LK E
Sbjct: 594 ESK--ALLSALELKKKEYEELKEE 615
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 42.4 bits (98), Expect = 3e-04
Identities = 32/157 (20%), Positives = 77/157 (49%), Gaps = 11/157 (7%)
Query: 47 DIKKRLKDSEKENSLLKKRIRFLEEKLIARFEE--ETSSVGREQVNKAYHAYREVCIDRD 104
D ++++++ E++ +++IR EEK+ + E+ E + +EQ K ++C +
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 105 NLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLS 164
++ + +KM + E+++ +E ++ + ++ Q+ M WE E+
Sbjct: 628 KMQEQEEKMRRQE--------EKIREQEKKIREQEEKIREQEEMMQ-EQEEKMWEQEEKM 678
Query: 165 CDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQE 201
C+ + EQE ++ R+E + E++ +Q + QE
Sbjct: 679 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,270,829
Number of Sequences: 37866
Number of extensions: 345002
Number of successful extensions: 2518
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 1779
Number of HSP's gapped (non-prelim): 1046
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.