Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 194272226
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 902 0.0
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 902 0.0
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 874 0.0
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 874 0.0
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 92 7e-19
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 92 1e-18
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 86 9e-17
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 80 3e-15
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 79 7e-15
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 72 8e-13
gi|66472382 nischarin [Homo sapiens] 71 2e-12
gi|31377705 centrosomal protein 97kDa [Homo sapiens] 70 3e-12
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 69 7e-12
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 67 3e-11
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s... 67 3e-11
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa... 67 3e-11
gi|164607156 axonemal dynein light chain 1 [Homo sapiens] 64 3e-10
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 60 3e-09
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo... 58 2e-08
gi|16904383 leucine rich repeat containing 7 [Homo sapiens] 55 1e-07
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 55 2e-07
gi|15529980 leucine rich repeat containing 46 [Homo sapiens] 55 2e-07
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 54 2e-07
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 54 2e-07
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 54 2e-07
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 54 3e-07
gi|61966709 leucine rich repeat containing 67 [Homo sapiens] 54 4e-07
gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 54 4e-07
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 54 4e-07
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 52 9e-07
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 902 bits (2332), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN
Sbjct: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
Query: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR
Sbjct: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
Query: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA
Sbjct: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
Query: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF
Sbjct: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
Query: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT
Sbjct: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
Query: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE
Sbjct: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
Query: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS
Sbjct: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
Query: 421 ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASGTF 457
ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASGTF
Sbjct: 421 ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASGTF 457
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 902 bits (2332), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN
Sbjct: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
Query: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR
Sbjct: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
Query: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA
Sbjct: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
Query: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF
Sbjct: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
Query: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT
Sbjct: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
Query: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE
Sbjct: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
Query: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS
Sbjct: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
Query: 421 ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASGTF 457
ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASGTF
Sbjct: 421 ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASGTF 457
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 874 bits (2257), Expect = 0.0
Identities = 446/455 (98%), Positives = 446/455 (98%)
Query: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN
Sbjct: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
Query: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR
Sbjct: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
Query: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA
Sbjct: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
Query: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF
Sbjct: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
Query: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT
Sbjct: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
Query: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE
Sbjct: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
Query: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS
Sbjct: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
Query: 421 ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASG 455
ISTLEKIVEGDLDEDLPNDLRA K V A G
Sbjct: 421 ISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVG 455
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 874 bits (2257), Expect = 0.0
Identities = 446/455 (98%), Positives = 446/455 (98%)
Query: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN
Sbjct: 1 MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDN 60
Query: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR
Sbjct: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
Query: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA
Sbjct: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
Query: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF
Sbjct: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
Query: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT
Sbjct: 241 VEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKT 300
Query: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE
Sbjct: 301 ELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISE 360
Query: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS
Sbjct: 361 LFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEIS 420
Query: 421 ISTLEKIVEGDLDEDLPNDLRAGRFQKFNYVEASG 455
ISTLEKIVEGDLDEDLPNDLRA K V A G
Sbjct: 421 ISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVG 455
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 92.4 bits (228), Expect = 7e-19
Identities = 61/142 (42%), Positives = 89/142 (62%), Gaps = 4/142 (2%)
Query: 33 QLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVW 91
++ K EG + K V +L L I I+NL + ++LR+L L +N I+KIE LE L L
Sbjct: 87 RIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEI 146
Query: 92 LDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIY 151
LD+SFN + IEG+D L L+ L L NN+ISKI++L L +LQ+L LG+NRI + NI
Sbjct: 147 LDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDT 206
Query: 152 LRRFKCLRTLSLSRNPISEAED 173
L L +L L +N I++ ++
Sbjct: 207 LTN---LESLFLGKNKITKLQN 225
Score = 88.2 bits (217), Expect = 1e-17
Identities = 68/202 (33%), Positives = 100/202 (49%), Gaps = 18/202 (8%)
Query: 48 LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107
L + F + I+ + + L+KL L NN I KIE L NL L L+L N I IE +DT
Sbjct: 147 LDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDT 206
Query: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNR---IDNMMNIIYLRRFKCLRTLSLS 164
L NLE L L N+I+K+ +LDAL L VLS+ +NR I+ + N++ LR L LS
Sbjct: 207 LTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRE------LYLS 260
Query: 165 RNPISEAEDYKMFICAYLPDLMYLDYRRIDD--HTKKLAE-------AKHQYSIDELKHQ 215
N I E + + D+ ++I++ H +L E + +DELK
Sbjct: 261 HNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGA 320
Query: 216 ENLMQAQLEDEQAQREELEKHK 237
+L LE Q++ + K
Sbjct: 321 RSLETVYLERNPLQKDPQYRRK 342
Score = 85.9 bits (211), Expect = 7e-17
Identities = 50/143 (34%), Positives = 80/143 (55%)
Query: 47 SLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLD 106
SL L I ++ NL NL L + +N + KIEGL+NL +L L LS N IE IEGL+
Sbjct: 212 SLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLE 271
Query: 107 TLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRN 166
L L + +NRI KI+++ L +LQ + +N +++ ++ L+ + L T+ L RN
Sbjct: 272 NNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERN 331
Query: 167 PISEAEDYKMFICAYLPDLMYLD 189
P+ + Y+ + LP + +D
Sbjct: 332 PLQKDPQYRRKVMLALPSVRQID 354
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 92.0 bits (227), Expect = 1e-18
Identities = 105/402 (26%), Positives = 175/402 (43%), Gaps = 60/402 (14%)
Query: 33 QLAKQEGILFKDVLSLQLDF---RNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHL 89
+L KQ+ + L+L L + I+NL + L L L N+I KIE L+ L L
Sbjct: 90 KLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKL 149
Query: 90 VWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSL--DALVKLQVLSLGNNRIDNMM 147
L+LS+N I IEG++ + NL+ L+L N I I L L+VL+L N+I ++
Sbjct: 150 RELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQ 209
Query: 148 NIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQY 207
+I L+ + L +L L NP+ Y F +L L L+ + + T+ EA ++
Sbjct: 210 DISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVT--TQDRQEAFERF 267
Query: 208 SIDELKHQENLMQAQLEDEQAQREELEKHKTAFVEH------LNGSFLFDSMYAEDSEGN 261
S++E++ ++ LE + + EEL+ +T F+E LN S ++M + S
Sbjct: 268 SLEEVER----LERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEE 323
Query: 262 NLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQ-------------EKRKTELDTFSEC 308
S L ELL+ + C +Y L+Q+ +E +
Sbjct: 324 LKSDLNTKNELLKQKTIELTRACQK--QYELEQELAFYKIDAKFEPLNYYPSEYAEIDKA 381
Query: 309 VREAIQENQEQGKRKIAKFEEKHLSSLSAIR-------EEL---------------ELPN 346
E+ + + KR + E + S A++ E+L +L +
Sbjct: 382 PDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLED 441
Query: 347 IEKMILECSADISELFDALMTLEMQLV------EQLEETINM 382
EK I +SEL D + E Q++ +QLEE I +
Sbjct: 442 KEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQL 483
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 85.5 bits (210), Expect = 9e-17
Identities = 64/183 (34%), Positives = 90/183 (49%), Gaps = 1/183 (0%)
Query: 48 LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107
L LD I I L NL L L NN I I GL L + L LS N IE I GL+
Sbjct: 220 LILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLPIKI-LCLSNNQIEMITGLED 278
Query: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNP 167
L L++L L +N+IS + L+ L+V++L +N+I + I Y++ LR L+L NP
Sbjct: 279 LKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENP 338
Query: 168 ISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQ 227
I E +Y F+ L L LD ++I K A K+ + + Q++L Q
Sbjct: 339 IQEKSEYWFFVIFMLLRLTELDQKKIKVEEKVSAVNKYDPPPEVVAAQDHLTHVVNSVMQ 398
Query: 228 AQR 230
QR
Sbjct: 399 PQR 401
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/124 (30%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Query: 46 LSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGL 105
L+L L N++ + L + +L+KL L N IE + + + +L+ L+ S NN+ T
Sbjct: 130 LNLTLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNF 189
Query: 106 DTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSR 165
NL+ +N+IS+I L A L L L N I+ + L L LSL+
Sbjct: 190 KPPKNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISG---LEMCNNLIHLSLAN 246
Query: 166 NPIS 169
N I+
Sbjct: 247 NKIT 250
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 80.5 bits (197), Expect = 3e-15
Identities = 59/171 (34%), Positives = 89/171 (52%), Gaps = 7/171 (4%)
Query: 24 DQGPQ---EEAGQLAKQEGILFKDVLS--LQLDFRNILRIDNLWQFENLRKLQLDNNIIE 78
D+GP+ +L KQ + L+ L L F+ RI+NL ++ LR L L +N I+
Sbjct: 83 DRGPRMTKSSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQ 142
Query: 79 KIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSL 138
KIE LE L L L N + IE L+ L L+ L+L NN I I++L L L L +
Sbjct: 143 KIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQM 202
Query: 139 GNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLD 189
+N ++ + +I +L+ L L LS N +S+ E + I +PDL L+
Sbjct: 203 AHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPE--ILSILESMPDLRVLN 251
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 79.3 bits (194), Expect = 7e-15
Identities = 56/141 (39%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 33 QLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWL 92
Q + +E IL+ D LSL+ + I N ++LR L +N I +I+ + NL L+ L
Sbjct: 82 QRSSEEKILYSDRLSLERQKLTVCPIIN--GEDHLRLLNFQHNFITRIQNISNLQKLISL 139
Query: 93 DLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYL 152
DL N IE I GL TL L L L NRI KI +L+ L L VL L N+I + NI +L
Sbjct: 140 DLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHL 199
Query: 153 RRFKCLRTLSLSRNPISEAED 173
LR L+L+RN +S ++
Sbjct: 200 CE---LRVLNLARNFLSHVDN 217
Score = 72.8 bits (177), Expect = 6e-13
Identities = 54/197 (27%), Positives = 101/197 (51%), Gaps = 5/197 (2%)
Query: 48 LQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDT 107
L L I +I NL ++L L L N I KIE + +L L L+L+ N + ++ L+
Sbjct: 161 LLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNG 220
Query: 108 LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNP 167
L +L +L+L +N+I+ + +D L LQ L L N I + ++ L L ++ NP
Sbjct: 221 LDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 280
Query: 168 ISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAE--AKHQYSIDELKHQENLMQAQLE- 224
I++ YK + + L LD +RI + +++A AK + H+++L++ +
Sbjct: 281 IAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRL 340
Query: 225 --DEQAQREELEKHKTA 239
+ A++ +L++ + A
Sbjct: 341 TINNVARQWDLQQQRVA 357
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 72.4 bits (176), Expect = 8e-13
Identities = 54/165 (32%), Positives = 82/165 (49%), Gaps = 9/165 (5%)
Query: 47 SLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLD 106
++ L NI +I+ + NL+ L L +N I +IEGL L L L+LS N I +EGL+
Sbjct: 47 AVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLE 106
Query: 107 TLVNLEDLSLFNNRISKIDSLDAL----VKLQVLSLGNNRIDNMMNIIY-LRRFKCLRTL 161
L+NL L++ N I + L L KL+ + L +NRID++ +++ + L L
Sbjct: 107 ELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGLHFLTNL 166
Query: 162 SLSR----NPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAE 202
L + NP+ Y+ I LP L LD + I L E
Sbjct: 167 ILEKDGDDNPVCRLPGYRAVILQTLPQLRILDCKNIFGEPVNLTE 211
Score = 64.3 bits (155), Expect = 2e-10
Identities = 43/117 (36%), Positives = 64/117 (54%), Gaps = 1/117 (0%)
Query: 53 RNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLE 112
+ + I L L + L N I KIE ++++ +L LDLS N I IEGL+TL L
Sbjct: 31 KGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLC 90
Query: 113 DLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFK-CLRTLSLSRNPI 168
L+L N I+K++ L+ L+ L L++ N ID++ +I L K LR + L N I
Sbjct: 91 TLNLSCNLITKVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRI 147
Score = 29.6 bits (65), Expect = 5.9
Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 29/168 (17%)
Query: 292 LKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMI 351
LK+QE RK EL+T E +A + Q+ ++IAK E+KH + +E++++ + + M
Sbjct: 583 LKEQEHRK-ELET-REFFTDA--DFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYM- 637
Query: 352 LECSADISELFDALMTLEMQLVEQLEETINMFERNIVDMVGLFI------ENVQSLMAQC 405
D+ F +T+E + + +++ + I SL+
Sbjct: 638 -----DLENEFRIALTVEARRFQDVKDGFENVATELAKSKHALIWAQRKENESSSLIKDL 692
Query: 406 RDLENHHHEKLLEIS-------------ISTLEKIVEGDLDEDLPNDL 440
+ KL E+S I+TLE ++E D + + +L
Sbjct: 693 TCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIEL 740
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/136 (33%), Positives = 74/136 (54%), Gaps = 2/136 (1%)
Query: 47 SLQLDFRNILRID-NLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGL 105
+L L +I ID ++ + L L +N + ++ L++L +LV LDLS+N + ++EGL
Sbjct: 291 TLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGL 350
Query: 106 DT-LVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLS 164
T L N++ L+L N + + L L L L L +NRI+ M + + CL +SL
Sbjct: 351 HTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLL 410
Query: 165 RNPISEAEDYKMFICA 180
NP+S DY+ + A
Sbjct: 411 NNPLSIIPDYRTKVLA 426
>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
Length = 865
Score = 70.5 bits (171), Expect = 3e-12
Identities = 54/191 (28%), Positives = 90/191 (47%), Gaps = 31/191 (16%)
Query: 30 EAGQLAKQEGI-LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAH 88
+ Q+ K E + K ++ L + ++R+ + + LR L L +N I +EGL+ L H
Sbjct: 44 DKNQIIKLENLEKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHNSIGCVEGLKELVH 103
Query: 89 LVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQ-------------- 134
L WL+L+ NN++ +E +++ L+ L L +N IS+I L LV L+
Sbjct: 104 LEWLNLAGNNLKAMEQINSCTALQHLDLSDNNISQIGDLSKLVSLKTLLLHGNIITSLRM 163
Query: 135 ----------VLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAE------DYKMFI 178
+LSL N I ++ I +L L LS+ NP A DY+ +I
Sbjct: 164 APAYLPRSLAILSLAENEIRDLNEISFLASLTELEQLSIMNNPCVMATPSIPGFDYRPYI 223
Query: 179 CAYLPDLMYLD 189
++ +L LD
Sbjct: 224 VSWCLNLRVLD 234
Score = 63.9 bits (154), Expect = 3e-10
Identities = 46/140 (32%), Positives = 76/140 (54%), Gaps = 7/140 (5%)
Query: 44 DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103
D+ +L LD I++++NL + + L +L + NN + ++ G+ L L L+L N+I +E
Sbjct: 37 DIHTLILDKNQIIKLENLEKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHNSIGCVE 96
Query: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163
GL LV+LE L+L N + ++ +++ LQ L L +N N+ I L + L+TL L
Sbjct: 97 GLKELVHLEWLNLAGNNLKAMEQINSCTALQHLDLSDN---NISQIGDLSKLVSLKTLLL 153
Query: 164 SRNPISEAEDYKMFICAYLP 183
N I+ AYLP
Sbjct: 154 HGNIITSLR----MAPAYLP 169
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 69.3 bits (168), Expect = 7e-12
Identities = 75/263 (28%), Positives = 122/263 (46%), Gaps = 25/263 (9%)
Query: 66 NLRKLQLDNNIIEKIEGLENLAH-LVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKI 124
+L +L L IE++E ++ L L L N I IE + L LE L+L N I KI
Sbjct: 22 SLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKI 81
Query: 125 DSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPD 184
++L+ +L L L N I + +I L+ L+ L L NP + + Y+ F+ A LP
Sbjct: 82 ENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQ 141
Query: 185 LMYLDYRRIDDHTKKLAEAKHQYSIDE--LKHQEN---LMQAQLEDEQAQREELEKHK-- 237
L +LD + I+ + +A YS+ E ++ QE L +A+L+ E+AQR+ E+ K
Sbjct: 142 LKWLDGKEIEPSER--IKALQDYSVIEPQIREQEKDHCLKRAKLK-EEAQRKHQEEDKNE 198
Query: 238 -------------TAFVEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIIC 284
T L+ D + A D+E +N L + LE + +
Sbjct: 199 DKRSNAGFDGRWYTDINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLEFWNKPCLFTP 258
Query: 285 VNIFEYGLKQQEKRKTELDTFSE 307
+ E L+ EK++ + + SE
Sbjct: 259 ESRLE-TLRHMEKQRKKQEKLSE 280
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/157 (29%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
Query: 66 NLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKID 125
NL L L N I KIE + +L L L+L+ N + ++ L+ L +L +L+L +N+I+ +
Sbjct: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
Query: 126 SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDL 185
+D L LQ L L N I + ++ L L ++ NPI++ YK + + L
Sbjct: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
Query: 186 MYLDYRRIDDHTKKLAE--AKHQYSIDELKHQENLMQ 220
LD +RI + +++A AK + H+++L++
Sbjct: 124 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLK 160
>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 67.4 bits (163), Expect = 3e-11
Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 5/199 (2%)
Query: 33 QLAKQEGILFKDVLSLQLDFRNILRIDNL--WQFENLRKLQLDNNIIEKIEGLENLAHLV 90
Q+ EGI + +L L +I + L + +L ++L N +E G+ NL L
Sbjct: 145 QITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLK 203
Query: 91 WLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVK-LQVLSLGNNRIDNMMNI 149
L L+ N ++ +EGL+ L NL L L +N+I + +K LQ L+L N + N+ +
Sbjct: 204 NLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGEL 263
Query: 150 IYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSI 209
LR LR L L NP ++ Y+ +P L LD ++ + A+ Q +
Sbjct: 264 AKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ-RL 322
Query: 210 DELKHQENLMQAQLEDEQA 228
E K QE Q LE EQ+
Sbjct: 323 KEEKEQEPEPQRDLEPEQS 341
>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 67.4 bits (163), Expect = 3e-11
Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 5/199 (2%)
Query: 33 QLAKQEGILFKDVLSLQLDFRNILRIDNL--WQFENLRKLQLDNNIIEKIEGLENLAHLV 90
Q+ EGI + +L L +I + L + +L ++L N +E G+ NL L
Sbjct: 145 QITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLK 203
Query: 91 WLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVK-LQVLSLGNNRIDNMMNI 149
L L+ N ++ +EGL+ L NL L L +N+I + +K LQ L+L N + N+ +
Sbjct: 204 NLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGEL 263
Query: 150 IYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSI 209
LR LR L L NP ++ Y+ +P L LD ++ + A+ Q +
Sbjct: 264 AKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQ-RL 322
Query: 210 DELKHQENLMQAQLEDEQA 228
E K QE Q LE EQ+
Sbjct: 323 KEEKEQEPEPQRDLEPEQS 341
>gi|164607156 axonemal dynein light chain 1 [Homo sapiens]
Length = 190
Score = 63.9 bits (154), Expect = 3e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Query: 60 NLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVN-LEDLSLFN 118
+L N KL L N IEKI L L +L L L NNI+ + GL+ + + LE+L +
Sbjct: 43 SLSMLANCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISY 102
Query: 119 NRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISE 170
N I K+ + + KL++L + NN + + + L CL L NP+ E
Sbjct: 103 NFIEKLKGIHIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEE 154
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 60.5 bits (145), Expect = 3e-09
Identities = 49/174 (28%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Query: 67 LRKLQLDN--NIIEKIEGLE-NLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRI-S 122
+R+L LDN + KIEGL +L +L L + ++ L L L+ L L NRI
Sbjct: 19 VRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFG 78
Query: 123 KIDSL-DALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAY 181
+D L + L L L+L N++ ++ + L++ +CL++L L ++ DY+ +
Sbjct: 79 GLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKL 138
Query: 182 LPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEK 235
LP L YLD +D ++A+ +E + +E + +DE + EE ++
Sbjct: 139 LPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDE 192
>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
sapiens]
Length = 255
Score = 58.2 bits (139), Expect = 2e-08
Identities = 44/138 (31%), Positives = 72/138 (52%), Gaps = 3/138 (2%)
Query: 68 RKLQLDNNIIEKIEGL-ENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKI-D 125
R+L L I IE L L +D S N I ++G L L+ L + NNRI +I +
Sbjct: 22 RELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGE 81
Query: 126 SLD-ALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPD 184
LD AL L L L NN + + ++ L K L LS+ RNP++ + Y++++ +P
Sbjct: 82 GLDQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQ 141
Query: 185 LMYLDYRRIDDHTKKLAE 202
+ LD++++ ++ AE
Sbjct: 142 VRVLDFQKVKLKERQEAE 159
>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
Length = 1537
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/102 (36%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 63 QFENLRKLQLDNNIIEKIEG-LENLAHLVWLDLSFNNIETIE-GLDTLVNLEDLSLFNNR 120
Q +NLR+L +DNN ++ + G + L LV+LD+S N IET++ + LEDL L +N
Sbjct: 205 QIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNM 264
Query: 121 ISKI-DSLDALVKLQVLSLGNNRIDNMMNII----YLRRFKC 157
+ ++ DS+ L KL L + +N++ + N I L F C
Sbjct: 265 LQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDC 306
Score = 29.3 bits (64), Expect = 7.8
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 92 LDLSFNNIETI-EGLDTLVNLEDLSLFNNRISKIDS-LDALVKLQVLSLGNNRIDNMMNI 149
L L N IE + + L L LS+ +N +S + + + +LV L+ L + N +
Sbjct: 51 LYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPEN 110
Query: 150 IYLRRFKCLRTLSLSRNPISEAED 173
I + KCL + S NPIS+ D
Sbjct: 111 I--KCCKCLTIIEASVNPISKLPD 132
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/212 (25%), Positives = 97/212 (45%), Gaps = 29/212 (13%)
Query: 66 NLRKLQLDNNIIE--KIEGL-ENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRIS 122
++++L LDN+ K+EGL + L +L + +I L L L+ L L +NR+S
Sbjct: 18 DVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVS 77
Query: 123 KIDSLDALVK----LQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFI 178
L+ L + L L+L N+I ++ I L++ + L++L L ++ DY+ +
Sbjct: 78 --GGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENV 135
Query: 179 CAYLPDLMYLDYRRIDDHTKKLAEAK--------HQYSIDELKHQENLMQAQLEDEQAQR 230
LP L YLD DD ++A+ + DE ++ E+ + E+++ +
Sbjct: 136 FKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEE 195
Query: 231 EELEKHKTAFVEHLNGSFLFDSMYAEDSEGNN 262
EE E+ + E ED EG N
Sbjct: 196 EEGEEEDVSGEEE------------EDEEGYN 215
>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
Length = 321
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/221 (27%), Positives = 99/221 (44%), Gaps = 33/221 (14%)
Query: 30 EAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHL 89
E G+L+++ ++ +++LD I I NL +NL L L N KI+ +ENLA
Sbjct: 31 EDGELSEKMFHTLDELQTVRLDREGITTIRNLEGLQNLHSLYLQGN---KIQQIENLA-- 85
Query: 90 VWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNI 149
+ +L LSL N+I ++++L L LQ L L N I+ +
Sbjct: 86 -----------------CIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK-- 126
Query: 150 IYLRRF-KCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDH--TKKLAEAKHQ 206
L F + L L+LS N + + Y+ + LP L+ LD + + + + + EA
Sbjct: 127 --LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDEASSD 184
Query: 207 YSIDELKH---QENLMQAQLEDEQAQREELEKHKTAFVEHL 244
EL E +LE E ++ E + +TA EHL
Sbjct: 185 EEFPELSGPFCSERGFLKELEQELSRHRE-HRQQTALTEHL 224
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 54.3 bits (129), Expect = 2e-07
Identities = 47/150 (31%), Positives = 79/150 (52%), Gaps = 7/150 (4%)
Query: 46 LSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENL-AHLVWLDLSFNNIETI-- 102
L L + + ++ ++ ++LR+++L+NN +E I L + A++ L L+ N I I
Sbjct: 79 LDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILP 138
Query: 103 EGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLS 162
E L +LE L L +N IS++ + ++L+ L L +NR+ +M + L L
Sbjct: 139 EHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLK 198
Query: 163 LSRNPISEAEDYKMFICAYLPDLMYLDYRR 192
L+RN IS A KMF LP L +L+ R
Sbjct: 199 LNRNRIS-AIPPKMF---KLPQLQHLELNR 224
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/114 (35%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 62 WQFENLRKLQLD-NNIIEKIEG-LENLAHLVWLDLSFNNIETI--EGLDTLVNLEDLSLF 117
W N+ LQLD NN+ E +G L L L L LS N I I + + L +L L
Sbjct: 260 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 319
Query: 118 NNRISKID--SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPIS 169
N +S++D S L L L +GNNR+ + + + R L+TL L N IS
Sbjct: 320 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF-RGLSSLKTLDLKNNEIS 372
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/203 (26%), Positives = 98/203 (48%), Gaps = 9/203 (4%)
Query: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
L +NL++L LD+N + +GL + +V+LD S N++ +EG++ L+ L L N
Sbjct: 965 LESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNY 1024
Query: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
+S++ SL+ LV L+ L L +N I + + L+ +++S+N +++ F+
Sbjct: 1025 LSELPSLENLVLLRELHLDDNSI-STVEAFSSYWLPLLQNITISQNSLTKIVPLFHFVSL 1083
Query: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
+ + + + + D + YS+ EL +L L E R+ L K A
Sbjct: 1084 ---EKLDVSHNCLSDLKSAIKWFDACYSLHEL----SLTGNPLLQETNWRDSLLKVLPA- 1135
Query: 241 VEHLNGSFLFDSMYAEDSEGNNL 263
+ LNG+ L + + E N L
Sbjct: 1136 LRILNGNILNSNSESRTEEHNQL 1158
Score = 49.3 bits (116), Expect = 7e-06
Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 6/142 (4%)
Query: 43 KDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETI 102
K++ L LD ++ L + L +N + +EG+EN L L L N + +
Sbjct: 969 KNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSEL 1028
Query: 103 EGLDTLVNLEDLSLFNNRISKIDSLDA--LVKLQVLSLGNNRIDNMMNIIYLRRFKCLRT 160
L+ LV L +L L +N IS +++ + L LQ +++ N ++ I+ L F L
Sbjct: 1029 PSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQN---SLTKIVPLFHFVSLEK 1085
Query: 161 LSLSRNPISEAED-YKMFICAY 181
L +S N +S+ + K F Y
Sbjct: 1086 LDVSHNCLSDLKSAIKWFDACY 1107
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 58 IDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLF 117
+ L + NL+ L L + + L N L ++D N+IE IE + L NL + L
Sbjct: 811 LSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIE-CENLENLCVVLLN 869
Query: 118 NNRISKIDSLDALVKLQVLSLGNNRI 143
N+++ + LD +Q L L N+I
Sbjct: 870 KNQLTSLHGLDGCTNIQCLELSYNKI 895
Score = 38.5 bits (88), Expect = 0.013
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 8/138 (5%)
Query: 82 GLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNN 141
GLE+L +L L L N + +GL + L +N ++ ++ ++ LQ+L L N
Sbjct: 964 GLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGN 1023
Query: 142 RIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLA 201
+ + + L LR L L N IS E + + +LP L + + + K+
Sbjct: 1024 YLSELPS---LENLVLLRELHLDDNSISTVEAFSSY---WLPLLQNITISQ--NSLTKIV 1075
Query: 202 EAKHQYSIDELKHQENLM 219
H S+++L N +
Sbjct: 1076 PLFHFVSLEKLDVSHNCL 1093
Score = 35.8 bits (81), Expect = 0.083
Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Query: 58 IDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLF 117
+ +L + L+ + N IE IE ENL +L + L+ N + ++ GLD N++ L L
Sbjct: 833 LHSLSNCKKLKYIDAQENHIEAIE-CENLENLCVVLLNKNQLTSLHGLDGCTNIQCLELS 891
Query: 118 NNRISKI 124
N+I++I
Sbjct: 892 YNKITRI 898
Score = 29.6 bits (65), Expect = 5.9
Identities = 35/149 (23%), Positives = 73/149 (48%), Gaps = 20/149 (13%)
Query: 213 KHQENL--MQAQLEDEQAQ-REELEKHKTAFVEHLNGSFL-----FDSMYAEDSEGNNLS 264
+H+E + + Q+E+E+ + +++ EK K + ++ N + + + + A G
Sbjct: 249 QHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYG---- 304
Query: 265 YLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKI 324
P + E +E+ K K + K++E RK L+ E ++ +E+ KR+
Sbjct: 305 --PIIKEQIESKKRKAQEWKEKEAKIRQKEEENRK-RLEEEQRIKEERKKQKEEERKRRE 361
Query: 325 AKFEEKHLSSLSAIREELE-LPNIEKMIL 352
++EEK + +++E E L + EK+IL
Sbjct: 362 KEYEEKK----NIVKQEREQLISKEKIIL 386
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
[Homo sapiens]
Length = 1336
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/203 (26%), Positives = 98/203 (48%), Gaps = 9/203 (4%)
Query: 61 LWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNR 120
L +NL++L LD+N + +GL + +V+LD S N++ +EG++ L+ L L N
Sbjct: 965 LESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNY 1024
Query: 121 ISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICA 180
+S++ SL+ LV L+ L L +N I + + L+ +++S+N +++ F+
Sbjct: 1025 LSELPSLENLVLLRELHLDDNSI-STVEAFSSYWLPLLQNITISQNSLTKIVPLFHFVSL 1083
Query: 181 YLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAF 240
+ + + + + D + YS+ EL +L L E R+ L K A
Sbjct: 1084 ---EKLDVSHNCLSDLKSAIKWFDACYSLHEL----SLTGNPLLQETNWRDSLLKVLPA- 1135
Query: 241 VEHLNGSFLFDSMYAEDSEGNNL 263
+ LNG+ L + + E N L
Sbjct: 1136 LRILNGNILNSNSESRTEEHNQL 1158
Score = 49.3 bits (116), Expect = 7e-06
Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 6/142 (4%)
Query: 43 KDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETI 102
K++ L LD ++ L + L +N + +EG+EN L L L N + +
Sbjct: 969 KNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSEL 1028
Query: 103 EGLDTLVNLEDLSLFNNRISKIDSLDA--LVKLQVLSLGNNRIDNMMNIIYLRRFKCLRT 160
L+ LV L +L L +N IS +++ + L LQ +++ N ++ I+ L F L
Sbjct: 1029 PSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQN---SLTKIVPLFHFVSLEK 1085
Query: 161 LSLSRNPISEAED-YKMFICAY 181
L +S N +S+ + K F Y
Sbjct: 1086 LDVSHNCLSDLKSAIKWFDACY 1107
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 58 IDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLF 117
+ L + NL+ L L + + L N L ++D N+IE IE + L NL + L
Sbjct: 811 LSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIE-CENLENLCVVLLN 869
Query: 118 NNRISKIDSLDALVKLQVLSLGNNRI 143
N+++ + LD +Q L L N+I
Sbjct: 870 KNQLTSLHGLDGCTNIQCLELSYNKI 895
Score = 38.5 bits (88), Expect = 0.013
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 8/138 (5%)
Query: 82 GLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNN 141
GLE+L +L L L N + +GL + L +N ++ ++ ++ LQ+L L N
Sbjct: 964 GLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGN 1023
Query: 142 RIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLA 201
+ + + L LR L L N IS E + + +LP L + + + K+
Sbjct: 1024 YLSELPS---LENLVLLRELHLDDNSISTVEAFSSY---WLPLLQNITISQ--NSLTKIV 1075
Query: 202 EAKHQYSIDELKHQENLM 219
H S+++L N +
Sbjct: 1076 PLFHFVSLEKLDVSHNCL 1093
Score = 35.8 bits (81), Expect = 0.083
Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Query: 58 IDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLF 117
+ +L + L+ + N IE IE ENL +L + L+ N + ++ GLD N++ L L
Sbjct: 833 LHSLSNCKKLKYIDAQENHIEAIE-CENLENLCVVLLNKNQLTSLHGLDGCTNIQCLELS 891
Query: 118 NNRISKI 124
N+I++I
Sbjct: 892 YNKITRI 898
Score = 29.6 bits (65), Expect = 5.9
Identities = 35/149 (23%), Positives = 73/149 (48%), Gaps = 20/149 (13%)
Query: 213 KHQENL--MQAQLEDEQAQ-REELEKHKTAFVEHLNGSFL-----FDSMYAEDSEGNNLS 264
+H+E + + Q+E+E+ + +++ EK K + ++ N + + + + A G
Sbjct: 249 QHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYG---- 304
Query: 265 YLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKI 324
P + E +E+ K K + K++E RK L+ E ++ +E+ KR+
Sbjct: 305 --PIIKEQIESKKRKAQEWKEKEAKIRQKEEENRK-RLEEEQRIKEERKKQKEEERKRRE 361
Query: 325 AKFEEKHLSSLSAIREELE-LPNIEKMIL 352
++EEK + +++E E L + EK+IL
Sbjct: 362 KEYEEKK----NIVKQEREQLISKEKIIL 386
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 53.9 bits (128), Expect = 3e-07
Identities = 45/142 (31%), Positives = 76/142 (53%), Gaps = 7/142 (4%)
Query: 54 NILRIDNLWQFENLRKLQLDNNIIEKIEGLENL-AHLVWLDLSFNNIETI--EGLDTLVN 110
+ ++ ++ ++LR+++L+NN +E I L + A++ L L+ N I I E L +
Sbjct: 27 SFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQS 86
Query: 111 LEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISE 170
LE L L +N IS++ + ++L+ L L +NR+ +M + L L L+RN IS
Sbjct: 87 LETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRIS- 145
Query: 171 AEDYKMFICAYLPDLMYLDYRR 192
A KMF LP L +L+ R
Sbjct: 146 AIPPKMF---KLPQLQHLELNR 164
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/114 (35%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 62 WQFENLRKLQLD-NNIIEKIEG-LENLAHLVWLDLSFNNIETI--EGLDTLVNLEDLSLF 117
W N+ LQLD NN+ E +G L L L L LS N I I + + L +L L
Sbjct: 200 WGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLT 259
Query: 118 NNRISKID--SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPIS 169
N +S++D S L L L +GNNR+ + + + R L+TL L N IS
Sbjct: 260 FNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF-RGLSSLKTLDLKNNEIS 312
Score = 29.6 bits (65), Expect = 5.9
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 24/89 (26%)
Query: 108 LVNLEDLSLFNNRIS--KIDSLDALVKLQVLSLGNNRIDNMMNI---------------- 149
L ++ L +NR+S K S+ L L+ + L NN ++ + N+
Sbjct: 13 LFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR 72
Query: 150 ------IYLRRFKCLRTLSLSRNPISEAE 172
+L+ F+ L TL LS N ISE +
Sbjct: 73 IVEILPEHLKEFQSLETLDLSSNNISELQ 101
>gi|61966709 leucine rich repeat containing 67 [Homo sapiens]
Length = 228
Score = 53.5 bits (127), Expect = 4e-07
Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 5/139 (3%)
Query: 43 KDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETI 102
K + + +NI I++L +NL L L +N I +I L +L L L N I I
Sbjct: 28 KKITHINFSDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCI 87
Query: 103 EGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRR-----FKC 157
E L +L LE L L N I+ I+ L+ L +L+ L + N R+ +++ R K
Sbjct: 88 ENLRSLKKLEKLYLGGNYIAVIEGLEGLGELRELHVENQRLPLGEKLLFDPRTLHSLAKS 147
Query: 158 LRTLSLSRNPISEAEDYKM 176
L L++S N I + D ++
Sbjct: 148 LCILNISNNNIDDITDLEL 166
Score = 50.4 bits (119), Expect = 3e-06
Identities = 44/126 (34%), Positives = 62/126 (49%), Gaps = 8/126 (6%)
Query: 41 LFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIE 100
L K++ L L I +I NL NL L L NN I IE L +L L L L N I
Sbjct: 48 LCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCIENLRSLKKLEKLYLGGNYIA 107
Query: 101 TIEGLDTLVNLEDLSLFNNRISKID-------SLDALVK-LQVLSLGNNRIDNMMNIIYL 152
IEGL+ L L +L + N R+ + +L +L K L +L++ NN ID++ ++ L
Sbjct: 108 VIEGLEGLGELRELHVENQRLPLGEKLLFDPRTLHSLAKSLCILNISNNNIDDITDLELL 167
Query: 153 RRFKCL 158
L
Sbjct: 168 ENLNQL 173
>gi|62912472 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 2 [Homo sapiens]
Length = 915
Score = 53.5 bits (127), Expect = 4e-07
Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 9/139 (6%)
Query: 39 GILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKI-----EGLENLAHLVWLD 93
G+ +L LQ + + + LW+ +L+ L+LD N+I + EGL +L HL WLD
Sbjct: 60 GLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL-WLD 118
Query: 94 LSFNNIETIEGLDTLVNLEDLSLFNNRISKID--SLDALVKLQVLSLGNNRIDNMMNIIY 151
+ + L+ L L+ ++L NRIS I + L L VL L NNRI ++ +
Sbjct: 119 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 178
Query: 152 LRRFKCLRTLSLSRNPISE 170
L TL L+ N + E
Sbjct: 179 -EGLHNLETLDLNYNKLQE 196
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/62 (38%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 84 ENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKI--DSLDALVKLQVLSLGNN 141
+ L L L+LS N IE + L LE++ L +NRI +I D+ L LQ L L N
Sbjct: 297 QQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 142 RI 143
I
Sbjct: 357 AI 358
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 53.5 bits (127), Expect = 4e-07
Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 9/139 (6%)
Query: 39 GILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKI-----EGLENLAHLVWLD 93
G+ +L LQ + + + LW+ +L+ L+LD N+I + EGL +L HL WLD
Sbjct: 112 GLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHL-WLD 170
Query: 94 LSFNNIETIEGLDTLVNLEDLSLFNNRISKID--SLDALVKLQVLSLGNNRIDNMMNIIY 151
+ + L+ L L+ ++L NRIS I + L L VL L NNRI ++ +
Sbjct: 171 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 230
Query: 152 LRRFKCLRTLSLSRNPISE 170
L TL L+ N + E
Sbjct: 231 -EGLHNLETLDLNYNKLQE 248
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/62 (38%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 84 ENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKI--DSLDALVKLQVLSLGNN 141
+ L L L+LS N IE + L LE++ L +NRI +I D+ L LQ L L N
Sbjct: 349 QQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 408
Query: 142 RI 143
I
Sbjct: 409 AI 410
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 52.4 bits (124), Expect = 9e-07
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)
Query: 44 DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103
DV L L + + + +L +F+ L+ L L +N + I L L L L+ N I IE
Sbjct: 95 DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
Query: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163
GL L +L L L +N ++ I DA VK + M+N L+ LSL
Sbjct: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
Query: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199
+NP+ + Y+++I +LP + LD ++ + ++
Sbjct: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
Score = 35.8 bits (81), Expect = 0.083
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 17/99 (17%)
Query: 38 EGILFKDVLSLQLDFRNILRIDNLWQFEN-------------LRKLQLDNNIIEKIEGLE 84
E L K L+ +D ++ LW N L +L L+NN I +IEGL
Sbjct: 98 ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLH 157
Query: 85 NLAHLVWLDLSFNNI----ETIEGLDTLVNLEDLSLFNN 119
L L L L N + T++ L ++NL+ LSL+ N
Sbjct: 158 YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQN 196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,226,876
Number of Sequences: 37866
Number of extensions: 644839
Number of successful extensions: 4004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 307
Number of HSP's that attempted gapping in prelim test: 3357
Number of HSP's gapped (non-prelim): 768
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.