Guide to the Human Genome
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Search of human proteins with 194248079

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194248079 tripartite motif-containing 2 isoform 1 [Homo
sapiens]
         (771 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]  1556   0.0  
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]  1498   0.0  
gi|32454739 tripartite motif-containing 3 [Homo sapiens]             1033   0.0  
gi|32454737 tripartite motif-containing 3 [Homo sapiens]             1033   0.0  
gi|84993742 tripartite motif-containing 71 [Homo sapiens]             310   2e-84
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi...   152   9e-37
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi...   133   5e-31
gi|153791514 tripartite motif-containing 32 [Homo sapiens]            117   5e-26
gi|153792582 tripartite motif-containing 32 [Homo sapiens]            117   5e-26
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]            95   2e-19
gi|30794216 tripartite motif-containing 56 [Homo sapiens]              94   5e-19
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]       91   5e-18
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    87   8e-17
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    87   8e-17
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    84   5e-16
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    84   5e-16
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]    83   8e-16
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]    83   8e-16
gi|217035095 tripartite motif-containing 62 [Homo sapiens]             81   4e-15
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]    80   9e-15
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]    80   9e-15
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]    80   9e-15
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    79   2e-14
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    79   2e-14
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    79   2e-14
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]            78   4e-14
gi|27436877 tripartite motif-containing 59 [Homo sapiens]              77   5e-14
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    77   6e-14
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]     77   6e-14
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    77   6e-14

>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 1556 bits (4030), Expect = 0.0
 Identities = 771/771 (100%), Positives = 771/771 (100%)

Query: 1   MHRSGRYGTQQQRAGSKTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLERYKNP 60
           MHRSGRYGTQQQRAGSKTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLERYKNP
Sbjct: 1   MHRSGRYGTQQQRAGSKTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLERYKNP 60

Query: 61  KVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRT 120
           KVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRT
Sbjct: 61  KVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRT 120

Query: 121 PGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVP 180
           PGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVP
Sbjct: 121 PGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVP 180

Query: 181 LKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQK 240
           LKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQK
Sbjct: 181 LKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQK 240

Query: 241 TLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLV 300
           TLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLV
Sbjct: 241 TLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLV 300

Query: 301 KKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGE 360
           KKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGE
Sbjct: 301 KKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGE 360

Query: 361 GLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLY 420
           GLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLY
Sbjct: 361 GLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLY 420

Query: 421 TVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKR 480
           TVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKR
Sbjct: 421 TVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKR 480

Query: 481 PASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIF 540
           PASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIF
Sbjct: 481 PASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIF 540

Query: 541 SNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSG 600
           SNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSG
Sbjct: 541 SNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSG 600

Query: 601 KLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSN 660
           KLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSN
Sbjct: 601 KLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSN 660

Query: 661 NEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRI 720
           NEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRI
Sbjct: 661 NEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRI 720

Query: 721 QVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ 771
           QVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
Sbjct: 721 QVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ 771


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 1498 bits (3877), Expect = 0.0
 Identities = 744/744 (100%), Positives = 744/744 (100%)

Query: 28  MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC 87
           MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC
Sbjct: 1   MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC 60

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN
Sbjct: 61  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 120

Query: 148 HDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEID 207
           HDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEID
Sbjct: 121 HDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEID 180

Query: 208 SALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQ 267
           SALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQ
Sbjct: 181 SALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQ 240

Query: 268 LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD 327
           LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD
Sbjct: 241 LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD 300

Query: 328 FIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKT 387
           FIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKT
Sbjct: 301 FIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKT 360

Query: 388 GNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLK 447
           GNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLK
Sbjct: 361 GNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLK 420

Query: 448 VIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKG 507
           VIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKG
Sbjct: 421 VIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKG 480

Query: 508 RNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVA 567
           RNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVA
Sbjct: 481 RNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVA 540

Query: 568 VHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVF 627
           VHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVF
Sbjct: 541 VHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVF 600

Query: 628 IFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFG 687
           IFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFG
Sbjct: 601 IFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFG 660

Query: 688 SNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLA 747
           SNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLA
Sbjct: 661 SNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLA 720

Query: 748 LTSDGHVVVADSGNHCFKVYRYLQ 771
           LTSDGHVVVADSGNHCFKVYRYLQ
Sbjct: 721 LTSDGHVVVADSGNHCFKVYRYLQ 744


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 498/740 (67%), Positives = 609/740 (82%), Gaps = 7/740 (0%)

Query: 36  PSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSI 95
           P P V+ +DKQFL+CSICL+RY+ PKVLPCLHTFCERCLQNYIPA SLTLSCPVCRQTSI
Sbjct: 8   PGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSI 67

Query: 96  LPEKGVAALQNNFFITNLMDVLQRTP-GSNAEESSILETVTAVAAGKPLSCPNHDGNVME 154
           LPE+GV+ALQNNFFI++LM+ +Q+ P G++  E        +V AG+PLSCPNH+G  ME
Sbjct: 68  LPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDP---HPLSVVAGRPLSCPNHEGKTME 124

Query: 155 FYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFIS 214
           FYC++CETAMC EC  GEH EH TV L+DVVEQHKA+LQ QL+AV  RLP++ +A+  + 
Sbjct: 125 FYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVG 184

Query: 215 EIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQG 274
            I  QL  +KA  +  I + F++L++ L  RK  L+ +LE   G K KVLQSQLDTL QG
Sbjct: 185 GISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQG 244

Query: 275 QESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEG 334
           QE I S  +F  QAL  G+  EVLLV+K M E+L  LA Q FP  P EN QL+ ++E +G
Sbjct: 245 QEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDG 304

Query: 335 LKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTA 394
           L++S+ NLG +LTT+A A ETVATGEGLRQ ++GQP S+T+TTKDKDG L +TG+A L A
Sbjct: 305 LRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRA 364

Query: 395 ELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADV 454
           E++ PDG+     ++D+KNGTYE +YT + EG+  LS+ LY Q +RGSPF+++ +R  D+
Sbjct: 365 EITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDL 424

Query: 455 SPTTEGVKRRVKSPGS--GHVKQKAVKRPASMYSTG-KRKENPIEDDLIFRVGTKGRNKG 511
            P+ + VKRRVKSPG    HV+QKAV+RP+SMYSTG KRK+NPIED+L+FRVG++GR KG
Sbjct: 425 PPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKG 484

Query: 512 EFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPS 571
           EFTNLQGV+A+++G+I++ADSNNQC+Q+FSN+GQFK RFG+RGRSPGQLQRPTGVAV  +
Sbjct: 485 EFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTN 544

Query: 572 GDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQP 631
           GDII+ADYDN+WVSIFS +GKFKTKIG+G+LMGPKGV+VDRNGHIIVVDNK+CCVF FQP
Sbjct: 545 GDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQP 604

Query: 632 NGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGE 691
           NGK+V RFG RG  DR FAGPHF AVN+ NEI++TDFHNHSVKV++ +GEF+ KFGS+GE
Sbjct: 605 NGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGE 664

Query: 692 GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSD 751
           GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD SGSFLSYINTSA+PLYGPQGLALTSD
Sbjct: 665 GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSD 724

Query: 752 GHVVVADSGNHCFKVYRYLQ 771
           GHVVVAD+GNHCFK YRYLQ
Sbjct: 725 GHVVVADAGNHCFKAYRYLQ 744


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 498/740 (67%), Positives = 609/740 (82%), Gaps = 7/740 (0%)

Query: 36  PSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSI 95
           P P V+ +DKQFL+CSICL+RY+ PKVLPCLHTFCERCLQNYIPA SLTLSCPVCRQTSI
Sbjct: 8   PGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSI 67

Query: 96  LPEKGVAALQNNFFITNLMDVLQRTP-GSNAEESSILETVTAVAAGKPLSCPNHDGNVME 154
           LPE+GV+ALQNNFFI++LM+ +Q+ P G++  E        +V AG+PLSCPNH+G  ME
Sbjct: 68  LPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDP---HPLSVVAGRPLSCPNHEGKTME 124

Query: 155 FYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFIS 214
           FYC++CETAMC EC  GEH EH TV L+DVVEQHKA+LQ QL+AV  RLP++ +A+  + 
Sbjct: 125 FYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVG 184

Query: 215 EIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQG 274
            I  QL  +KA  +  I + F++L++ L  RK  L+ +LE   G K KVLQSQLDTL QG
Sbjct: 185 GISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQG 244

Query: 275 QESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEG 334
           QE I S  +F  QAL  G+  EVLLV+K M E+L  LA Q FP  P EN QL+ ++E +G
Sbjct: 245 QEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDG 304

Query: 335 LKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTA 394
           L++S+ NLG +LTT+A A ETVATGEGLRQ ++GQP S+T+TTKDKDG L +TG+A L A
Sbjct: 305 LRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRA 364

Query: 395 ELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADV 454
           E++ PDG+     ++D+KNGTYE +YT + EG+  LS+ LY Q +RGSPF+++ +R  D+
Sbjct: 365 EITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDL 424

Query: 455 SPTTEGVKRRVKSPGS--GHVKQKAVKRPASMYSTG-KRKENPIEDDLIFRVGTKGRNKG 511
            P+ + VKRRVKSPG    HV+QKAV+RP+SMYSTG KRK+NPIED+L+FRVG++GR KG
Sbjct: 425 PPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKG 484

Query: 512 EFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPS 571
           EFTNLQGV+A+++G+I++ADSNNQC+Q+FSN+GQFK RFG+RGRSPGQLQRPTGVAV  +
Sbjct: 485 EFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTN 544

Query: 572 GDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQP 631
           GDII+ADYDN+WVSIFS +GKFKTKIG+G+LMGPKGV+VDRNGHIIVVDNK+CCVF FQP
Sbjct: 545 GDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQP 604

Query: 632 NGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGE 691
           NGK+V RFG RG  DR FAGPHF AVN+ NEI++TDFHNHSVKV++ +GEF+ KFGS+GE
Sbjct: 605 NGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGE 664

Query: 692 GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSD 751
           GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD SGSFLSYINTSA+PLYGPQGLALTSD
Sbjct: 665 GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSD 724

Query: 752 GHVVVADSGNHCFKVYRYLQ 771
           GHVVVAD+GNHCFK YRYLQ
Sbjct: 725 GHVVVADAGNHCFKAYRYLQ 744


>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
          Length = 868

 Score =  310 bits (795), Expect = 2e-84
 Identities = 196/632 (31%), Positives = 317/632 (50%), Gaps = 50/632 (7%)

Query: 145 CPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKA-SLQVQLDAVNKRL 203
           C +HD  V+  YC +C   +CRECT G H  H  + L++ ++  +A ++Q+  DA   R 
Sbjct: 278 CQHHDDEVLHLYCDTCSVPICRECTMGRHGGHSFIYLQEALQDSRALTIQLLADAQQGR- 336

Query: 204 PEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV 263
             I  +++    +  Q+  +   +  ++ +     +K L  R+  LL ++E    +K K 
Sbjct: 337 QAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEERECELLWKVEKIRQVKAKS 396

Query: 264 LQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPREN 323
           L  Q++ L Q    ++S  +   Q L  G   ++LL + +M  ++ EL      L P+E+
Sbjct: 397 LYLQVEKLRQNLNKLESTISAVQQVLEEGRALDILLARDRMLAQVQELKTVRSLLQPQED 456

Query: 324 DQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGE 383
           D++ F    + L  +I + G + ++ A A  T ATG+GL++ + G+  S T+   D DGE
Sbjct: 457 DRVMFTPPDQALYLAIKSFGFV-SSGAFAPLTKATGDGLKRALQGKVASFTVIGYDHDGE 515

Query: 384 LCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSP 443
              +G   ++A +  PDG++   E+ D +NGTY   Y  Q EG+  +S+ L +QHI  SP
Sbjct: 516 PRLSGGDLMSAVVLGPDGNLFGAEVSDQQNGTYVVSYRPQLEGEHLVSVTLCNQHIENSP 575

Query: 444 FKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRV 503
           FK+ V++S                 G  +V    +  P   +                  
Sbjct: 576 FKV-VVKS-----------------GRSYV---GIGLPGLSF------------------ 596

Query: 504 GTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRP 563
           G++G + G+     GV+    G I++AD +N  +Q+F   G F  +FG  G  PGQ  RP
Sbjct: 597 GSEGDSDGKLCRPWGVSVDKEGYIIVADRSNNRIQVFKPCGAFHHKFGTLGSRPGQFDRP 656

Query: 564 TGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIG-----SGKLMGPKGVSVDRNGHIIV 618
            GVA   S  I++AD DN  + IF+ +G+F  K G     +G+   P  V+V+  G I+V
Sbjct: 657 AGVACDASRRIVVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWDVAVNSEGKILV 716

Query: 619 VDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQ 678
            D +   + +F P+G  + ++G  G   + F  P   A N    +++TDF+NH + V + 
Sbjct: 717 SDTRNHRIQLFGPDGVFLNKYGFEGALWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHP 776

Query: 679 EGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSAD 738
           + +     GS G GNGQF  P GVAVD  G IIVAD  N R+Q+F+ +GSFL        
Sbjct: 777 DCQSARFLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFESNGSFLCKFGAQGS 836

Query: 739 ---PLYGPQGLALTSDGHVVVADSGNHCFKVY 767
               +  P G+A+T DG +VV D GN+   V+
Sbjct: 837 GFGQMDRPSGIAITPDGMIVVVDFGNNRILVF 868



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 14/132 (10%)

Query: 648 QFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFM-------LKFGSNGEGNGQFNAPT 700
           Q  G H  +V   N+ I     N   KV  + G          L FGS G+ +G+   P 
Sbjct: 555 QLEGEHLVSVTLCNQHI----ENSPFKVVVKSGRSYVGIGLPGLSFGSEGDSDGKLCRPW 610

Query: 701 GVAVDSNGNIIVADWGNSRIQVFDGSGSF---LSYINTSADPLYGPQGLALTSDGHVVVA 757
           GV+VD  G IIVAD  N+RIQVF   G+F      + +       P G+A  +   +VVA
Sbjct: 611 GVSVDKEGYIIVADRSNNRIQVFKPCGAFHHKFGTLGSRPGQFDRPAGVACDASRRIVVA 670

Query: 758 DSGNHCFKVYRY 769
           D  NH  +++ +
Sbjct: 671 DKDNHRIQIFTF 682



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 10/69 (14%)

Query: 62  VLPCLHTFCERCLQNY-IPA-------HSLTLSCPVCRQTSILPE-KGVAALQNN-FFIT 111
           VLPCLH FC  CL+ + +PA         L L CPVC Q  +L E  G+ AL ++ F ++
Sbjct: 58  VLPCLHAFCRPCLEAHRLPAAGGGAAGEPLKLRCPVCDQKVVLAEAAGMDALPSSAFLLS 117

Query: 112 NLMDVLQRT 120
           NL+D +  T
Sbjct: 118 NLLDAVVAT 126


>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
           sapiens]
          Length = 580

 Score =  152 bits (385), Expect = 9e-37
 Identities = 120/471 (25%), Positives = 194/471 (41%), Gaps = 70/471 (14%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQNYIP----------------------------AH 81
           C +CL  +K P++LPCLHT C  CL+   P                              
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 82  SLTLSCPVCRQTSILPEKGVAALQ------NNFFITNLM--------------DVLQRTP 121
            + + CPVC     LP  GV AL       N+  + +L               +V +R  
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQ 148

Query: 122 GSNA------------EESSILETVTAVA-------AGKPLSCPNHDGNVMEFYCQSCET 162
              A            ++ +   T+  +         GKP+ CP H    +  +C+ C+ 
Sbjct: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDR 208

Query: 163 AMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTN 222
            +C++C  GEH EHP     +V+ +H  S+   L      +  ++ AL  I  I   L  
Sbjct: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268

Query: 223 QKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCS 282
           +  ++  D+ +  +   K +   +  LL +LE     K   LQ Q   L Q    +++  
Sbjct: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328

Query: 283 NFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFI-VETEGLKKSIHN 341
            FT   L  G++ E+L+ K+ + E+L +L    +   P  ND++ F   E  G  +    
Sbjct: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEKAGQCRGYEI 388

Query: 342 LGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTG--NAYLTAELSTP 399
            GTI T     ++ V  GE L +    Q  S T+  KD  GE+   G  N  +       
Sbjct: 389 YGTINTKEVDPAKCVLQGEDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDK 448

Query: 400 DGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIR 450
             S     + DNK+GTY   YT ++ G +T+ + + +QH++GSPF + V R
Sbjct: 449 KDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRR 499


>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
           sapiens]
          Length = 562

 Score =  133 bits (335), Expect = 5e-31
 Identities = 111/470 (23%), Positives = 187/470 (39%), Gaps = 86/470 (18%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQNYIP----------------------------AH 81
           C +CL  +K P++LPCLHT C  CL+   P                              
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 82  SLTLSCPVCRQTSILPEKGVAALQ------NNFFITNLM--------------DVLQRTP 121
            + + CPVC     LP  GV AL       N+  + +L               +V +R  
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQ 148

Query: 122 GSNA------------EESSILETVTAVA-------AGKPLSCPNHDGNVMEFYCQSCET 162
              A            ++ +   T+  +         GKP+ CP H    +  +C+ C+ 
Sbjct: 149 TCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDR 208

Query: 163 AMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTN 222
            +C++C  GEH EHP     +V+ +H  S+   L      +  ++ AL  I  I   L  
Sbjct: 209 PVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQK 268

Query: 223 QKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCS 282
           +  ++  D+ +  +   K +   +  LL +LE     K   LQ Q   L Q    +++  
Sbjct: 269 RVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGV 328

Query: 283 NFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNL 342
            FT   L  G++ E+L+ K+ + E+L +L    +   P  ND++ F  + +  +   + +
Sbjct: 329 EFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEKAGQCRGYEI 388

Query: 343 GTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTG--NAYLTAELSTPD 400
                              L +    Q  S T+  KD  GE+   G  N  +        
Sbjct: 389 -----------------YDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKK 431

Query: 401 GSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIR 450
            S     + DNK+GTY   YT ++ G +T+ + + +QH++GSPF + V R
Sbjct: 432 DSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRR 481


>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score =  117 bits (292), Expect = 5e-26
 Identities = 170/765 (22%), Positives = 291/765 (38%), Gaps = 174/765 (22%)

Query: 45  KQFLICSICLERYKN----PKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKG 100
           ++ L C IC+E +      PK+L C HT C +CL+  + +    + CP C +        
Sbjct: 15  REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSK-------- 66

Query: 101 VAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160
                    IT +  + Q T   N     I++T     A   L C +    +   +C+SC
Sbjct: 67  ---------ITRITSLTQLT--DNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115

Query: 161 ETAMCRECTEGEHAE--HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH 218
              +C  C E +H    H T+P+K+  E+ +               +    L  + E++ 
Sbjct: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRR--------------DFGEKLTRLRELMG 161

Query: 219 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 278
           +L  +KA++        + + K L  R   +L E    YG + + +Q +L          
Sbjct: 162 ELQRRKAAL--------EGVSKDLQARYKAVLQE----YGHEERRVQDEL---------A 200

Query: 279 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKS 338
           +S   FT      G+  EV     Q+ E+ + L +               I E + + + 
Sbjct: 201 RSRKFFT------GSLAEVEKSNSQVVEEQSYLLN---------------IAEVQAVSRC 239

Query: 339 IHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELST 398
            + L  I   +    E  A  E    T    P  +T+    +D EL K G+         
Sbjct: 240 DYFLAKIKQADVALLEETADEEEPELTA-SLPRELTL----QDVELLKVGHV-------- 286

Query: 399 PDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTT 458
             G +  G+ +           TV  E  + +      +    +       R  D+SP  
Sbjct: 287 --GPLQIGQAVKKPR-------TVNVEDSWAM------EATASAASTSVTFREMDMSP-- 329

Query: 459 EGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFR-VGTKGRNKGEFTNLQ 517
              +  V SP +   KQ+           G    + I+  L  + +G KG   G F    
Sbjct: 330 ---EEVVASPRASPAKQR-----------GPEAASNIQQCLFLKKMGAKGSTPGMFNLPV 375

Query: 518 GVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQR--------------P 563
            +  ++ G++L+AD  N  +Q+F+  G  K    IR RSP  +                P
Sbjct: 376 SLYVTSQGEVLVADRGNYRIQVFTRKGFLKE---IR-RSPSGIDSFVLSFLGADLPNLTP 431

Query: 564 TGVAVHPSGDIIIAD-YDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNK 622
             VA++  G I + D YDN  + +++ DG         +L  P G++   +G  +V D +
Sbjct: 432 LSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPWGITALPSGQFVVTDVE 489

Query: 623 ACCVFIFQPN-GKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 681
              ++ F  + G  V ++    +  R    P F   ++   +  T      + + N++ E
Sbjct: 490 GGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFTQ--GLGLNLENRQNE 543

Query: 682 FMLK-------FGSNGE----------GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 724
             L+        G +G+           N  F    G+ VD+ G++IVAD     I  F 
Sbjct: 544 HHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFP 603

Query: 725 GSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRY 769
             G +   I    + L  P G+ALT  G ++V D  +HC K+Y Y
Sbjct: 604 KGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645


>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score =  117 bits (292), Expect = 5e-26
 Identities = 170/765 (22%), Positives = 291/765 (38%), Gaps = 174/765 (22%)

Query: 45  KQFLICSICLERYKN----PKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKG 100
           ++ L C IC+E +      PK+L C HT C +CL+  + +    + CP C +        
Sbjct: 15  REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSK-------- 66

Query: 101 VAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160
                    IT +  + Q T   N     I++T     A   L C +    +   +C+SC
Sbjct: 67  ---------ITRITSLTQLT--DNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115

Query: 161 ETAMCRECTEGEHAE--HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH 218
              +C  C E +H    H T+P+K+  E+ +               +    L  + E++ 
Sbjct: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRR--------------DFGEKLTRLRELMG 161

Query: 219 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 278
           +L  +KA++        + + K L  R   +L E    YG + + +Q +L          
Sbjct: 162 ELQRRKAAL--------EGVSKDLQARYKAVLQE----YGHEERRVQDEL---------A 200

Query: 279 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKS 338
           +S   FT      G+  EV     Q+ E+ + L +               I E + + + 
Sbjct: 201 RSRKFFT------GSLAEVEKSNSQVVEEQSYLLN---------------IAEVQAVSRC 239

Query: 339 IHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELST 398
            + L  I   +    E  A  E    T    P  +T+    +D EL K G+         
Sbjct: 240 DYFLAKIKQADVALLEETADEEEPELTA-SLPRELTL----QDVELLKVGHV-------- 286

Query: 399 PDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTT 458
             G +  G+ +           TV  E  + +      +    +       R  D+SP  
Sbjct: 287 --GPLQIGQAVKKPR-------TVNVEDSWAM------EATASAASTSVTFREMDMSP-- 329

Query: 459 EGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFR-VGTKGRNKGEFTNLQ 517
              +  V SP +   KQ+           G    + I+  L  + +G KG   G F    
Sbjct: 330 ---EEVVASPRASPAKQR-----------GPEAASNIQQCLFLKKMGAKGSTPGMFNLPV 375

Query: 518 GVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQR--------------P 563
            +  ++ G++L+AD  N  +Q+F+  G  K    IR RSP  +                P
Sbjct: 376 SLYVTSQGEVLVADRGNYRIQVFTRKGFLKE---IR-RSPSGIDSFVLSFLGADLPNLTP 431

Query: 564 TGVAVHPSGDIIIAD-YDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNK 622
             VA++  G I + D YDN  + +++ DG         +L  P G++   +G  +V D +
Sbjct: 432 LSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPWGITALPSGQFVVTDVE 489

Query: 623 ACCVFIFQPN-GKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 681
              ++ F  + G  V ++    +  R    P F   ++   +  T      + + N++ E
Sbjct: 490 GGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFTQ--GLGLNLENRQNE 543

Query: 682 FMLK-------FGSNGE----------GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 724
             L+        G +G+           N  F    G+ VD+ G++IVAD     I  F 
Sbjct: 544 HHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFP 603

Query: 725 GSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRY 769
             G +   I    + L  P G+ALT  G ++V D  +HC K+Y Y
Sbjct: 604 KGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645


>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
          Length = 358

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 76/288 (26%), Positives = 126/288 (43%), Gaps = 36/288 (12%)

Query: 43  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQNYIPAH--------SLTLS------C 87
           ++KQ LIC ICLE +  P V LPC H  C +C  +   A         S T+S      C
Sbjct: 20  LEKQ-LICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           P CR   +L   GV  LQ N  + N++D+ ++      E S  L +     A + L C  
Sbjct: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESSRPLHS----KAEQHLMCEE 128

Query: 148 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHKASLQ---VQLDAVNKRL 203
           H+   +  YC SCE   C  C   G H +    PL  + ++ K+ L      L A N R+
Sbjct: 129 HEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRV 188

Query: 204 PEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV 263
             + + ++ + + I   + ++  +   ++  F+ L   L  RK  LL  L      + + 
Sbjct: 189 QAVITQMEEVCQTIEDNSRRQKQL---LNQRFESLCAVLEERKGELLQALARE---QEEK 242

Query: 264 LQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNEL 311
           LQ     + Q  + +++ S     A+    E ++ L  +Q  E +N++
Sbjct: 243 LQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKV 290


>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
          Length = 755

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 79/345 (22%), Positives = 140/345 (40%), Gaps = 71/345 (20%)

Query: 28  MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSC 87
           M S G++ PS ++  +   FL C ICLE+ + PK LPCLHT+C+ CL     A    + C
Sbjct: 1   MVSHGSS-PS-LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQL--ADGGRVRC 56

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           P CR+T  +P +GVA+ + NFF+  L+D+++      A     L       A  PL    
Sbjct: 57  PECRETVPVPPEGVASFKTNFFVNGLLDLVK------ARACGDLRAGKPACALCPLVGGT 110

Query: 148 HDGNVMEFYCQSCETAMCRECTEGEHA--------------------------------- 174
             G      C  C   +C+ C +G                                    
Sbjct: 111 STGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCP 170

Query: 175 EHPTVPLKDVVEQ------HKASLQVQLD--------AVNKRLP--------------EI 206
           +HP   L+ + +        +  L   LD        AV  R P              E+
Sbjct: 171 QHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVEL 230

Query: 207 DSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQS 266
           ++A +   E + +L  Q A +   +    + + + L  +K  +L +L  +     +  + 
Sbjct: 231 EAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARE 290

Query: 267 QLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNEL 311
           +L  L   ++  ++ + F  + L+ G E E+L ++  ++++L +L
Sbjct: 291 RLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQL 335



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 40/175 (22%), Positives = 77/175 (44%), Gaps = 11/175 (6%)

Query: 555 RSPGQLQRPTGVAVHPSG--DIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDR 612
           R PG  + P    + P G  +I++AD  N+ +  FS +G +K  +   +   P  V+  +
Sbjct: 500 RMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQ 559

Query: 613 NGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHS 672
           +    V  + +  +++  PNG++  R   R     Q +  H  A   + + +      H 
Sbjct: 560 SA---VAFSASARLYLINPNGEVQWR---RALSLSQAS--HAVAALPSGDRVAVSVAGH- 610

Query: 673 VKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSG 727
           V+V+N EG    +F   G+ +    A   +     G+ + +DW  + + + DG G
Sbjct: 611 VEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLG 665



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 2/105 (1%)

Query: 537 VQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTK 596
           V++++ +G   +RF   G++   L+    +   P G  + +D+    V I    G+   +
Sbjct: 611 VEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGE 670

Query: 597 IGSGKLMG--PKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRF 639
                L G  P  VSVD+ G+I +   +   V I  P G ++  F
Sbjct: 671 YKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDF 715


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 72/290 (24%), Positives = 119/290 (41%), Gaps = 34/290 (11%)

Query: 40  VRQIDKQFLICSICLERYKNPKV-LPCLHTFCERCLQNYIPA---------HSLTLS--- 86
           +  ++KQ LIC ICLE +  P V LPC H  C +C  +   A          S+++S   
Sbjct: 14  MENLEKQ-LICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGR 72

Query: 87  --CPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLS 144
             CP CR   I+   GV  LQ N  + N++D+ ++   S             +  G    
Sbjct: 73  FRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSR-----------PLQKGSHPM 121

Query: 145 CPNHDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHKASLQ---VQLDAVN 200
           C  H+   +  YC +CE   C  C   G H      PL+ V +  K  L      L A N
Sbjct: 122 CKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVAGN 181

Query: 201 KRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLK 260
            R+  I + L+    +  + ++Q   + +++   FD L   L+ +KS LL  +      K
Sbjct: 182 DRVQTIITQLEDSRRVTKENSHQ---VKEELSQKFDTLYAILDEKKSELLQRITQEQEKK 238

Query: 261 HKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNE 310
              +++ +    +  +          Q+L+       LL  KQ+ + + E
Sbjct: 239 LSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVE 288


>gi|74027251 tripartite motif-containing 33 protein isoform beta
           [Homo sapiens]
          Length = 1110

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 93/399 (23%), Positives = 156/399 (39%), Gaps = 93/399 (23%)

Query: 14  AGSKTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLE-----RYKNPKVLPCLHT 68
           A   +AGPP             P P    +D     C++C +     R   PK+LPCLH+
Sbjct: 106 APGPSAGPP-------------PGPPASLLDT----CAVCQQSLQSRREAEPKLLPCLHS 148

Query: 69  FCERCLQNY-------IPAHSL-------TLSCPVCRQTSILPEKGVAALQNNFFITNLM 114
           FC RCL          IP  S         + CPVCRQ     E     L +N+F+ +  
Sbjct: 149 FCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVCRQ-----ECRQIDLVDNYFVKDTS 203

Query: 115 DVLQRTPGSNAEES-----SILETVTAV-------------------------------- 137
           +     P S+ E+S     S  +  +AV                                
Sbjct: 204 EA----PSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKK 259

Query: 138 --------AAG-KPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQH 188
                   A+G +P+ CP H    ++ +C++C+   CR+C   EH EH    L++  +  
Sbjct: 260 EDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQ 319

Query: 189 KASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSV 248
           K +++  L  + ++   +  A   +   I ++      +  +I      L   +N +   
Sbjct: 320 KGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKS 379

Query: 249 LLMELE-VNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEK 307
           LL +LE V    + K+LQ Q D +      +K   NFT  A+  G+ T +L  K+ ++ +
Sbjct: 380 LLQQLENVTKERQMKLLQQQND-ITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQ 438

Query: 308 LNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTIL 346
           L  +        P  N  + F  +     K++ NLG ++
Sbjct: 439 LRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLV 477


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
           [Homo sapiens]
          Length = 1127

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 93/399 (23%), Positives = 156/399 (39%), Gaps = 93/399 (23%)

Query: 14  AGSKTAGPPCQWSRMASEGTNIPSPVVRQIDKQFLICSICLE-----RYKNPKVLPCLHT 68
           A   +AGPP             P P    +D     C++C +     R   PK+LPCLH+
Sbjct: 106 APGPSAGPP-------------PGPPASLLDT----CAVCQQSLQSRREAEPKLLPCLHS 148

Query: 69  FCERCLQNY-------IPAHSL-------TLSCPVCRQTSILPEKGVAALQNNFFITNLM 114
           FC RCL          IP  S         + CPVCRQ     E     L +N+F+ +  
Sbjct: 149 FCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVCRQ-----ECRQIDLVDNYFVKDTS 203

Query: 115 DVLQRTPGSNAEES-----SILETVTAV-------------------------------- 137
           +     P S+ E+S     S  +  +AV                                
Sbjct: 204 EA----PSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKK 259

Query: 138 --------AAG-KPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQH 188
                   A+G +P+ CP H    ++ +C++C+   CR+C   EH EH    L++  +  
Sbjct: 260 EDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQ 319

Query: 189 KASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSV 248
           K +++  L  + ++   +  A   +   I ++      +  +I      L   +N +   
Sbjct: 320 KGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKS 379

Query: 249 LLMELE-VNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEK 307
           LL +LE V    + K+LQ Q D +      +K   NFT  A+  G+ T +L  K+ ++ +
Sbjct: 380 LLQQLENVTKERQMKLLQQQND-ITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQ 438

Query: 308 LNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTIL 346
           L  +        P  N  + F  +     K++ NLG ++
Sbjct: 439 LRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLV 477


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 92/379 (24%)

Query: 50  CSICLERYKN--PKVLPCLHTFCERCL---QNYI--PAHSL------------------- 83
           C++C +  ++  PK+LPCLH+FC+RCL   Q Y+  PA  L                   
Sbjct: 56  CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115

Query: 84  --------TLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSIL---- 131
                    + CPVC Q     E     + +NFF+ +  +V    P S  E+S+ +    
Sbjct: 116 SPFATQVGVIRCPVCSQ-----ECAERHIIDNFFVKDTTEV----PSSTVEKSNQVCTSC 166

Query: 132 ---------------------------------------ETVTAVAAG----KPLSCPNH 148
                                                  E V+  A G    +P+ CP H
Sbjct: 167 EDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFH 226

Query: 149 DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDS 208
               ++ YC++C+   CR+C   EH EH    +++  +  K  +   +  + ++   I  
Sbjct: 227 KKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKF 286

Query: 209 ALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV-LQSQ 267
               I   I ++   +  +  DI      L   +N +   LL +LE +    H++ L  Q
Sbjct: 287 TGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLE-SLAKDHRMKLMQQ 345

Query: 268 LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD 327
              +    + ++   +F+  A++ G+ T +L  K+ ++ +L  L        P  N+ + 
Sbjct: 346 QQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQ 405

Query: 328 FIVETEGLKKSIHNLGTIL 346
           F  +     ++I NLG+++
Sbjct: 406 FHCDPSFWAQNIINLGSLV 424


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 92/379 (24%)

Query: 50  CSICLERYKN--PKVLPCLHTFCERCL---QNYI--PAHSL------------------- 83
           C++C +  ++  PK+LPCLH+FC+RCL   Q Y+  PA  L                   
Sbjct: 56  CAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGS 115

Query: 84  --------TLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSIL---- 131
                    + CPVC Q     E     + +NFF+ +  +V    P S  E+S+ +    
Sbjct: 116 SPFATQVGVIRCPVCSQ-----ECAERHIIDNFFVKDTTEV----PSSTVEKSNQVCTSC 166

Query: 132 ---------------------------------------ETVTAVAAG----KPLSCPNH 148
                                                  E V+  A G    +P+ CP H
Sbjct: 167 EDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFH 226

Query: 149 DGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDS 208
               ++ YC++C+   CR+C   EH EH    +++  +  K  +   +  + ++   I  
Sbjct: 227 KKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKF 286

Query: 209 ALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV-LQSQ 267
               I   I ++   +  +  DI      L   +N +   LL +LE +    H++ L  Q
Sbjct: 287 TGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLE-SLAKDHRMKLMQQ 345

Query: 268 LDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLD 327
              +    + ++   +F+  A++ G+ T +L  K+ ++ +L  L        P  N+ + 
Sbjct: 346 QQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQ 405

Query: 328 FIVETEGLKKSIHNLGTIL 346
           F  +     ++I NLG+++
Sbjct: 406 FHCDPSFWAQNIINLGSLV 424


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 60/206 (29%), Positives = 89/206 (43%), Gaps = 19/206 (9%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFF 109
           CS+CLE  K P ++ C H FC+ C+  +         CPVCR+TS        +L+ N  
Sbjct: 29  CSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTS-----RYRSLRPN-- 81

Query: 110 ITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECT 169
                    R  GS  E +  L+ V      + L CP H    +  +C   + A+C  C 
Sbjct: 82  ---------RQLGSMVEIAKQLQAVKRKIRDESL-CPQHH-EALSLFCYEDQEAVCLICA 130

Query: 170 -EGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIV 228
               H  H  VPL D  +++K  LQ  L+ + ++L EI        +   +L     S  
Sbjct: 131 ISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRR 190

Query: 229 DDIHSTFDELQKTLNVRKSVLLMELE 254
             I   F+EL + L+  + VLL  LE
Sbjct: 191 QQILREFEELHRRLDEEQQVLLSRLE 216


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 60/206 (29%), Positives = 89/206 (43%), Gaps = 19/206 (9%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFF 109
           CS+CLE  K P ++ C H FC+ C+  +         CPVCR+TS        +L+ N  
Sbjct: 29  CSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTS-----RYRSLRPN-- 81

Query: 110 ITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECT 169
                    R  GS  E +  L+ V      + L CP H    +  +C   + A+C  C 
Sbjct: 82  ---------RQLGSMVEIAKQLQAVKRKIRDESL-CPQHH-EALSLFCYEDQEAVCLICA 130

Query: 170 -EGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIV 228
               H  H  VPL D  +++K  LQ  L+ + ++L EI        +   +L     S  
Sbjct: 131 ISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRR 190

Query: 229 DDIHSTFDELQKTLNVRKSVLLMELE 254
             I   F+EL + L+  + VLL  LE
Sbjct: 191 QQILREFEELHRRLDEEQQVLLSRLE 216


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 72/283 (25%), Positives = 120/283 (42%), Gaps = 28/283 (9%)

Query: 45  KQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSL--TLSCPVCRQTSILPEKGVA 102
           K  L+CSICL  Y++P  L C H FC RC+  +           CP CR+T   P     
Sbjct: 6   KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEP----- 60

Query: 103 ALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCET 162
           AL  +  + N+++     P        +   + A  A +P  C  HD   ++ +C +   
Sbjct: 61  ALAPSLKLANIVERYSSFP--------LDAILNARRAARP--CQAHD--KVKLFCLTDRA 108

Query: 163 AMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLT 221
            +C  C E   H +H    + D  ++ +  L+ QL A+     E   ALQ +   + +  
Sbjct: 109 LLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETK 168

Query: 222 NQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYG-----LKHKVLQSQLDTLLQGQE 276
           +   S+   I   F+ L + L  R+  +L ELE +       ++ KV Q     L + QE
Sbjct: 169 SSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKV-QRYSQQLRKVQE 227

Query: 277 SIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNE--LADQDFP 317
             +      A+   H     V  + +++  K++E  L  +DFP
Sbjct: 228 GAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFP 270


>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
          Length = 452

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 61/224 (27%), Positives = 95/224 (42%), Gaps = 35/224 (15%)

Query: 43  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQN-------YIPAHSLT-------LSC 87
           ++KQ LIC ICLE +  P V LPC H  C +C  +       Y+P    T         C
Sbjct: 20  LEKQ-LICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRC 78

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           P CR   +L   GV  LQ N  + N++D+ ++      ++S            +P+ C  
Sbjct: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSD-----------QPM-CEE 126

Query: 148 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHKASLQ---VQLDAVNKRL 203
           H+   +  YC +CE   C  C   G H +    PL  V ++ K+ L      L   N R+
Sbjct: 127 HEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRV 186

Query: 204 PEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKS 247
             + S L+   + I +   ++     ++   FD L   L  RK+
Sbjct: 187 QGVISQLEDTCKTIEECCRKQK---QELCEKFDYLYGILEERKN 227


>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
          Length = 548

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 61/224 (27%), Positives = 95/224 (42%), Gaps = 35/224 (15%)

Query: 43  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQN-------YIPAHSLT-------LSC 87
           ++KQ LIC ICLE +  P V LPC H  C +C  +       Y+P    T         C
Sbjct: 20  LEKQ-LICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRC 78

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           P CR   +L   GV  LQ N  + N++D+ ++      ++S            +P+ C  
Sbjct: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSD-----------QPM-CEE 126

Query: 148 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHKASLQ---VQLDAVNKRL 203
           H+   +  YC +CE   C  C   G H +    PL  V ++ K+ L      L   N R+
Sbjct: 127 HEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRV 186

Query: 204 PEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKS 247
             + S L+   + I +   ++     ++   FD L   L  RK+
Sbjct: 187 QGVISQLEDTCKTIEECCRKQK---QELCEKFDYLYGILEERKN 227


>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
          Length = 540

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 61/224 (27%), Positives = 95/224 (42%), Gaps = 35/224 (15%)

Query: 43  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQN-------YIPAHSLT-------LSC 87
           ++KQ LIC ICLE +  P V LPC H  C +C  +       Y+P    T         C
Sbjct: 20  LEKQ-LICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRFRC 78

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           P CR   +L   GV  LQ N  + N++D+ ++      ++S            +P+ C  
Sbjct: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKSD-----------QPM-CEE 126

Query: 148 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHKASLQ---VQLDAVNKRL 203
           H+   +  YC +CE   C  C   G H +    PL  V ++ K+ L      L   N R+
Sbjct: 127 HEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSNDRV 186

Query: 204 PEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKS 247
             + S L+   + I +   ++     ++   FD L   L  RK+
Sbjct: 187 QGVISQLEDTCKTIEECCRKQK---QELCEKFDYLYGILEERKN 227


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 51/164 (31%), Positives = 76/164 (46%), Gaps = 18/164 (10%)

Query: 48  LICSIC-----LERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVA 102
           L C +C     L+  K P++L C HT C  CL   +P H   + CP  RQ + L + GV 
Sbjct: 29  LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTR-LPLHGRAIRCPFDRQVTDLGDSGVW 87

Query: 103 ALQNNFFITNLMDVLQRTP--GSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160
            L+ NF +  L++ LQ  P     A E SI      ++    + C   + ++   YC  C
Sbjct: 88  GLKKNFALLELLERLQNGPIGQYGAAEESI-----GISGESIIRCDEDEAHLASVYCTVC 142

Query: 161 ETAMCRECTEGEH-----AEHPTVPLKDVVEQHKASLQVQLDAV 199
            T +C EC++  H     A+H  VPL D   +     Q Q+ A+
Sbjct: 143 ATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAI 186


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 51/164 (31%), Positives = 76/164 (46%), Gaps = 18/164 (10%)

Query: 48  LICSIC-----LERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVA 102
           L C +C     L+  K P++L C HT C  CL   +P H   + CP  RQ + L + GV 
Sbjct: 29  LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTR-LPLHGRAIRCPFDRQVTDLGDSGVW 87

Query: 103 ALQNNFFITNLMDVLQRTP--GSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160
            L+ NF +  L++ LQ  P     A E SI      ++    + C   + ++   YC  C
Sbjct: 88  GLKKNFALLELLERLQNGPIGQYGAAEESI-----GISGESIIRCDEDEAHLASVYCTVC 142

Query: 161 ETAMCRECTEGEH-----AEHPTVPLKDVVEQHKASLQVQLDAV 199
            T +C EC++  H     A+H  VPL D   +     Q Q+ A+
Sbjct: 143 ATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAI 186


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 51/164 (31%), Positives = 76/164 (46%), Gaps = 18/164 (10%)

Query: 48  LICSIC-----LERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVA 102
           L C +C     L+  K P++L C HT C  CL   +P H   + CP  RQ + L + GV 
Sbjct: 29  LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTR-LPLHGRAIRCPFDRQVTDLGDSGVW 87

Query: 103 ALQNNFFITNLMDVLQRTP--GSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160
            L+ NF +  L++ LQ  P     A E SI      ++    + C   + ++   YC  C
Sbjct: 88  GLKKNFALLELLERLQNGPIGQYGAAEESI-----GISGESIIRCDEDEAHLASVYCTVC 142

Query: 161 ETAMCRECTEGEH-----AEHPTVPLKDVVEQHKASLQVQLDAV 199
            T +C EC++  H     A+H  VPL D   +     Q Q+ A+
Sbjct: 143 ATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAI 186


>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 27/163 (16%)

Query: 43  IDKQFLICSICLERYKNPKV-LPCLHTFCERCLQNYIPAH--------SLTLS------C 87
           ++KQ LIC ICLE +  P V LPC H  C +C  +   A         S T+S      C
Sbjct: 20  LEKQ-LICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRC 78

Query: 88  PVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPN 147
           P CR   +L   GV  LQ N  + N++D+ ++      E S  L +     A + L C  
Sbjct: 79  PSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESSRPLHS----KAEQHLMCEE 128

Query: 148 HDGNVMEFYCQSCETAMCREC-TEGEHAEHPTVPLKDVVEQHK 189
           H+   +  YC SCE   C  C   G H +    PL  + ++ K
Sbjct: 129 HEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQK 171


>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
          Length = 403

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 57/223 (25%), Positives = 92/223 (41%), Gaps = 40/223 (17%)

Query: 48  LICSICLERYKNPKVLPCLHTFCERCLQNYIPAHS---------LTLSCPVCRQTSILPE 98
           L C IC   +++P+VLPC HTFC  CL+N + A           + L CP CR  + +  
Sbjct: 8   LTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAP 67

Query: 99  KGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQ 158
            G+ +L  NF +  +++  Q+    +                  ++CP H    +  YC 
Sbjct: 68  TGIESLPVNFALRAIIEKYQQEDHPDI-----------------VTCPEHYRQPLNVYCL 110

Query: 159 SCETAMCREC-TEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEII 217
             +  +C  C T G+H  HP   L+    + K + Q  L+ +       D+    ++ +I
Sbjct: 111 LDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLT------DTHWTDLTHLI 164

Query: 218 HQLTNQKASIVDDIHST-------FDELQKTLNVRKSVLLMEL 253
            +L  QK+     I          F EL  TL  +K   L  L
Sbjct: 165 EKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTAL 207


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 22/214 (10%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQNY--IPAHSLTLS--CPVCRQTSILPEKGVAALQ 105
           C IC    + P  + C H FC  CL  Y  IP   L  S  CP+C++          + +
Sbjct: 16  CPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPF-----RPGSFR 70

Query: 106 NNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMC 165
            N+ + N+++ ++R           L+ V+ +  G+   C  H G  + F+C+  E  +C
Sbjct: 71  PNWQLANVVENIER-----------LQLVSTLGLGEEDVCQEH-GEKIYFFCEDDEMQLC 118

Query: 166 RECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQK 224
             C E GEHA H    L+D    ++  +   L  + K   EI       ++ +  L  Q 
Sbjct: 119 VVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178

Query: 225 ASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYG 258
           ++    + S F  L+K L  ++S+LL +LE   G
Sbjct: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDG 212


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 65/255 (25%), Positives = 105/255 (41%), Gaps = 31/255 (12%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQN------------YIPAHSLTLSCPVCRQ----T 93
           CSICLE ++ P  + C H+FC  C+                 A    L CP CR+    +
Sbjct: 29  CSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPARPS 88

Query: 94  SILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVM 153
            + P + +AA+     +     +    PG +  ++       A A      C  H G   
Sbjct: 89  QLRPNRQLAAVAT---LLRRFSLPAAAPGEHGSQA-------AAARAAAARCGQH-GEPF 137

Query: 154 EFYCQSCETAMCRECTEG-EHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQF 212
           + YCQ    A+C  C    EH EH  +PL + V++ K  L+ +L  + K L + +     
Sbjct: 138 KLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRST 197

Query: 213 ISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLL 272
             +   +L  Q A+  + + + F  L+  L  ++  LL  LE    L  +V Q Q + L 
Sbjct: 198 EKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLE---ELSREVAQKQNENLA 254

Query: 273 QGQESIKSCSNFTAQ 287
           Q    I   S  ++Q
Sbjct: 255 QLGVEITQLSKLSSQ 269


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 22/214 (10%)

Query: 50  CSICLERYKNPKVLPCLHTFCERCLQNY--IPAHSLTLS--CPVCRQTSILPEKGVAALQ 105
           C IC    + P  + C H FC  CL  Y  IP   L  S  CP+C++          + +
Sbjct: 16  CPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPF-----RPGSFR 70

Query: 106 NNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMC 165
            N+ + N+++ ++R           L+ V+ +  G+   C  H G  + F+C+  E  +C
Sbjct: 71  PNWQLANVVENIER-----------LQLVSTLGLGEEDVCQEH-GEKIYFFCEDDEMQLC 118

Query: 166 RECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQK 224
             C E GEHA H    L+D    ++  +   L  + K   EI       ++ +  L  Q 
Sbjct: 119 VVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178

Query: 225 ASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYG 258
           ++    + S F  L+K L  ++S+LL +LE   G
Sbjct: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDG 212


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,902,218
Number of Sequences: 37866
Number of extensions: 1380211
Number of successful extensions: 4531
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 211
Number of HSP's that attempted gapping in prelim test: 3699
Number of HSP's gapped (non-prelim): 713
length of query: 771
length of database: 18,247,518
effective HSP length: 110
effective length of query: 661
effective length of database: 14,082,258
effective search space: 9308372538
effective search space used: 9308372538
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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