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Search of human proteins with 190343008
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190343008 SP110 nuclear body protein isoform b [Homo
sapiens]
(549 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens] 1108 0.0
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens] 1070 0.0
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 1070 0.0
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 206 3e-53
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens] 206 3e-53
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 131 2e-30
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 119 7e-27
gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens] 97 5e-20
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 61 3e-09
gi|38016945 deformed epidermal autoregulatory factor 1 [Homo sap... 58 3e-08
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 50 4e-06
gi|13435377 glucocorticoid modulatory element binding protein 1 ... 48 2e-05
gi|13435375 glucocorticoid modulatory element binding protein 1 ... 48 2e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 47 3e-05
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 46 1e-04
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 46 1e-04
gi|6912568 glucocorticoid modulatory element binding protein 2 [... 46 1e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 44 3e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 44 3e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 44 3e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 44 3e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 44 3e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 44 4e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 44 4e-04
gi|189011568 adenomatous polyposis coli [Homo sapiens] 44 5e-04
gi|189011566 adenomatous polyposis coli [Homo sapiens] 44 5e-04
gi|53759122 adenomatous polyposis coli [Homo sapiens] 44 5e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 44 5e-04
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 44 5e-04
gi|157785645 SPEG complex locus [Homo sapiens] 44 5e-04
>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
Length = 549
Score = 1108 bits (2865), Expect = 0.0
Identities = 549/549 (100%), Positives = 549/549 (100%)
Query: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP
Sbjct: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
Query: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL
Sbjct: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
Query: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV
Sbjct: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
Query: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE
Sbjct: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
Query: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG
Sbjct: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
Query: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE
Sbjct: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
Query: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA
Sbjct: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
Query: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM
Sbjct: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
Query: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRI 540
KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRI
Sbjct: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRI 540
Query: 541 NLKRELNSK 549
NLKRELNSK
Sbjct: 541 NLKRELNSK 549
>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
Length = 689
Score = 1070 bits (2767), Expect = 0.0
Identities = 530/530 (100%), Positives = 530/530 (100%)
Query: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP
Sbjct: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
Query: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL
Sbjct: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
Query: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV
Sbjct: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
Query: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE
Sbjct: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
Query: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG
Sbjct: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
Query: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE
Sbjct: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
Query: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA
Sbjct: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
Query: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM
Sbjct: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
Query: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK 530
KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK
Sbjct: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK 530
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 1070 bits (2767), Expect = 0.0
Identities = 530/530 (100%), Positives = 530/530 (100%)
Query: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP
Sbjct: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
Query: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL
Sbjct: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
Query: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV
Sbjct: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
Query: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE
Sbjct: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
Query: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG
Sbjct: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
Query: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE
Sbjct: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
Query: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA
Sbjct: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
Query: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM
Sbjct: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
Query: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK 530
KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK
Sbjct: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK 530
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 206 bits (525), Expect = 3e-53
Identities = 178/652 (27%), Positives = 283/652 (43%), Gaps = 118/652 (18%)
Query: 6 RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65
R + + +F+HF K+ I+ AI K FPF EGL D +IT +M+ +S ++CRNL+PV RVV
Sbjct: 47 RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
Query: 66 HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116
+N+L++LE+TFNL +L LFS +N++EYP+L+ IY+ F+ V ER+ R
Sbjct: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
Query: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158
+ LE TG SL P + P PP+ S PC +
Sbjct: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
Query: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190
SQQ++E ++ P++ + + G
Sbjct: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
Query: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244
S SV + + E + + ASD ++ D E +P E+ S
Sbjct: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
Query: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285
S P I +++P E ND +E QE + + P +K +KR I +
Sbjct: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
Query: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345
S G S+HG ++ P ++ + + + ++ +
Sbjct: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
Query: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400
S EE+ + +S + G SQ ++ + P G+ + + +Q D
Sbjct: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
Query: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451
D NS + K R K +S R ++K + + + + + +K +RG+
Sbjct: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
Query: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496
PK + ++F S+LPVTCGE KG LYK++ K G+S KCI++ED W
Sbjct: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
Query: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRINLKRELNS 548
TP EFE+EG +KNWK +IRC G TL L+++ L PP KR L S
Sbjct: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILES 689
>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
Length = 879
Score = 206 bits (525), Expect = 3e-53
Identities = 178/652 (27%), Positives = 283/652 (43%), Gaps = 118/652 (18%)
Query: 6 RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65
R + + +F+HF K+ I+ AI K FPF EGL D +IT +M+ +S ++CRNL+PV RVV
Sbjct: 47 RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
Query: 66 HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116
+N+L++LE+TFNL +L LFS +N++EYP+L+ IY+ F+ V ER+ R
Sbjct: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
Query: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158
+ LE TG SL P + P PP+ S PC +
Sbjct: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
Query: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190
SQQ++E ++ P++ + + G
Sbjct: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
Query: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244
S SV + + E + + ASD ++ D E +P E+ S
Sbjct: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
Query: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285
S P I +++P E ND +E QE + + P +K +KR I +
Sbjct: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
Query: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345
S G S+HG ++ P ++ + + + ++ +
Sbjct: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
Query: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400
S EE+ + +S + G SQ ++ + P G+ + + +Q D
Sbjct: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
Query: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451
D NS + K R K +S R ++K + + + + + +K +RG+
Sbjct: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
Query: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496
PK + ++F S+LPVTCGE KG LYK++ K G+S KCI++ED W
Sbjct: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
Query: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRINLKRELNS 548
TP EFE+EG +KNWK +IRC G TL L+++ L PP KR L S
Sbjct: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILES 689
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 131 bits (329), Expect = 2e-30
Identities = 112/405 (27%), Positives = 181/405 (44%), Gaps = 36/405 (8%)
Query: 153 APRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEE 212
+P + T ++ ++ +E P + LP +EG +D + + EE E
Sbjct: 291 SPEGRDKETFDLKTPQVTNEG-EPEKGLCLLPGEGEEG------SDDCSEMCDGEEPQEA 343
Query: 213 MPSLLT-STVQVAS----DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQE 267
SL +V S D PQ+ ++ +P++ G E D+ E D EE QE
Sbjct: 344 SSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQE 403
Query: 268 VSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTC 327
SS+ + +R S+ H + + + +Q + + +C
Sbjct: 404 ASSSLA-------RRGSVSSELENHPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSC 456
Query: 328 NSTVETR---AQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHG 384
+ +ARTE + + + +D + GK P RR +G HG
Sbjct: 457 VMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGK-----PKRKRRKKRG-----HG 506
Query: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRF 442
+ +Q+ D+S + +V+ +KA K K R +++ K + S R
Sbjct: 507 WSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAA 566
Query: 443 QKNIHRRG--KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPN 500
QK + R K K +TVDF LPVTCG KGIL+KKK++ G VKCI+ EDG W TP
Sbjct: 567 QKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPT 626
Query: 501 EFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRINLKRE 545
EFE++G +KNW+ ++RC G L L+++G L PPRI +++
Sbjct: 627 EFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKK 671
Score = 117 bits (293), Expect = 3e-26
Identities = 109/375 (29%), Positives = 166/375 (44%), Gaps = 76/375 (20%)
Query: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
Query: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYE-------RQSRDTPILLE 122
++LE+TF S L LFS+INL YP+L IYRSF+ V + D P LL
Sbjct: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLL- 158
Query: 123 APTGLAEGS-SLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVL 181
P G E S + H + PQ S C EPG SS+ +++ D
Sbjct: 159 -PYGKQENSNACHEMDDIAVPQEALSSSPRC-----EPGFSSESCEQLALPKAGGGD-AE 211
Query: 182 PLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEM 241
P+L+ G + KL +++ E +SEEMP LL +V N
Sbjct: 212 DAPSLLPGGG----VSCKLAIQID-EGESEEMPKLLPYDTEVLESN-------------- 252
Query: 242 PHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGT 301
G + R S+ P +K+G++ R ++P++R++ K
Sbjct: 253 -----GMIDAAR-------------TYSTAPGEKQGEEEGR---NSPRKRNQDK------ 285
Query: 302 ASSRHGIQKKLKRVDQVPQKKDDSTCN---STVETRAQKARTECARKSRSEEIIDGTSEM 358
++ + P+ +D T + V + + C EE D SEM
Sbjct: 286 -----------EKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEM 334
Query: 359 NEGKRSQKTPSTPRR 373
+G+ Q+ S+ R
Sbjct: 335 CDGEEPQEASSSLAR 349
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 119 bits (298), Expect = 7e-27
Identities = 56/109 (51%), Positives = 82/109 (75%), Gaps = 5/109 (4%)
Query: 1 MFTMTRAMEEAL-----FQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEAC 55
+FT + ++E L F+HF KL I+ AI K FPF EGL D +IT +M+ +S ++C
Sbjct: 37 LFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSC 96
Query: 56 RNLIPVSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFK 104
RNL+PV RVV+N+L++LE+TFNLS+L LFS++N++EYP+L+ IY+SFK
Sbjct: 97 RNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFK 145
Score = 118 bits (296), Expect = 1e-26
Identities = 78/220 (35%), Positives = 112/220 (50%), Gaps = 17/220 (7%)
Query: 337 KARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVT 396
+AR E + + +D + GK P RR +G HG K
Sbjct: 182 EARKESDQACGKMDTVDIANNSTLGK-----PKRKRRKKKG-----HGWSRMGTRTQKNN 231
Query: 397 QRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRG--KP 452
Q+ D+S + +++ +KA K K R +++ K + S R QK + R K
Sbjct: 232 QQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKH 291
Query: 453 KSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAK 512
K +TVDF LPVTCG KGIL+K+K++ G+ KCI+ EDG W TP EFE++G +K
Sbjct: 292 KDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSK 351
Query: 513 NWKRNIRCEGMTLGELLKSGLLLCPPRI---NLKRELNSK 549
NW+ ++RC G L L++ G L PPRI N KR L S+
Sbjct: 352 NWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQ 391
>gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
Length = 172
Score = 96.7 bits (239), Expect = 5e-20
Identities = 50/100 (50%), Positives = 68/100 (68%)
Query: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
Query: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGAS 109
++LE+TF S L LFS+INL YP+L IYRSF+ S
Sbjct: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNENLS 139
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 60.8 bits (146), Expect = 3e-09
Identities = 70/310 (22%), Positives = 124/310 (40%), Gaps = 27/310 (8%)
Query: 157 SEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSL 216
S +SS SD S S + +E + S+ + +E + S
Sbjct: 193 SSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSK 252
Query: 217 LTSTVQVASDNLIPQIRDKEDPQEMPHSP-----LGSMPEIRDNSPEPNDPEEPQEVSST 271
+++ + ++NL Q + P+E+P P + P D N E + +
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNP 312
Query: 272 PSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTV 331
P+ + ++R + + R+ K + SR + + +R + P
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP------------ 360
Query: 332 ETRAQKARTECARKSRSEEIIDG-TSEMNEGKRSQKTP--STPRRVTQG---AASPGHGI 385
R + R + R S E I G SE+NE K +Q++P R++T + SP
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 386 QEKLQVVD-KVTQRKDDSTWNSEVMMRVQ---KARTKCARKSRSKEKKKEKDICSSSKRR 441
+++ +V D K ++ D NSE + + K R K +S+SKEK K K+ S R
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 442 FQKNIHRRGK 451
+K + R K
Sbjct: 481 EEKRMRSRSK 490
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/328 (21%), Positives = 132/328 (40%), Gaps = 24/328 (7%)
Query: 157 SEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSL 216
S +SS + S+S S SD A ++ + + K S+ + +E + S
Sbjct: 194 SSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRK-NSRKHKKEKKKRKKSK 252
Query: 217 LTSTVQVASDNLIPQIRDKEDPQEMPHSP-----LGSMPEIRDNSPEPNDPEEPQEVSST 271
+++ + ++NL Q + P+E+P P + P D N E + +
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNP 312
Query: 272 PSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTV 331
P+ + ++R + + R+ K + SR + + +R + P + +
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQ----- 367
Query: 332 ETRAQKARTECARKSRSEEIIDGT-SEMNEGKRSQKTPST--PRRVTQG---AASPGHGI 385
RAQ+ R S E I G SE+NE K +Q++P R++T + SP
Sbjct: 368 --RAQRMRV-----SSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 386 QEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQKN 445
+++ +V D + K+ + K + K KS+S+ K KEK + +N
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 446 IHRRGKPKSDTVDFHCSKLPVTCGEAKG 473
+R + +S D K ++KG
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKG 508
>gi|38016945 deformed epidermal autoregulatory factor 1 [Homo
sapiens]
Length = 565
Score = 57.8 bits (138), Expect = 3e-08
Identities = 28/73 (38%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Query: 462 SKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCE 521
S+LPV C G LYK ++ G +CI+ + W +P EFE ++K+WKR+IR
Sbjct: 201 SELPVRCRNISGTLYKNRLGSGGRGRCIKQGEN-WYSPTEFEAMAGRASSKDWKRSIRYA 259
Query: 522 GMTLGELLKSGLL 534
G L L++ G+L
Sbjct: 260 GRPLQCLIQDGIL 272
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 50.4 bits (119), Expect = 4e-06
Identities = 69/324 (21%), Positives = 119/324 (36%), Gaps = 47/324 (14%)
Query: 123 APTGLAEGSSLHTPLALPPPQP------------PQPSCSPCAPRVSEPGTSSQQSDEIL 170
A GL G L LP P P P+ P + PG + L
Sbjct: 130 AVAGLLPGGGL-----LPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGAN-------L 177
Query: 171 SESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIP 230
+ +D +L L + + + + V ++ + ++ S+E+ + V+ A +
Sbjct: 178 NSQSLAADQLLKLMSTV-DPKLNHVAAGLVSPSLKSDTSSKEIEEAM-KRVREAQSLISA 235
Query: 231 QIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKR 290
I + ++ HS S R +P + + S S K + R+R +P+R
Sbjct: 236 AIEPDKKEEKRRHSRSRSRSR-RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRS--KSPRR 292
Query: 291 RHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEE 350
R G + S + K K + + K ST +R R+SRS
Sbjct: 293 RRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRS-- 350
Query: 351 IIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMM 410
G RS K P +P+R + SP +EK + DK R + S
Sbjct: 351 ----------GTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS---- 396
Query: 411 RVQKARTKCARKSRSKEKKKEKDI 434
+K ++K K R ++ + +KD+
Sbjct: 397 --KKKKSKDKEKDRERKSESDKDV 418
>gi|13435377 glucocorticoid modulatory element binding protein 1
isoform 1 [Homo sapiens]
Length = 573
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 465 PVTCGEAKGI-LYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGM 523
P+TCGE+K I L+KK + G +VKC++ D ++P F K+WKR IR G+
Sbjct: 96 PITCGESKAILLWKKFVCPGINVKCVKFND-QLISPKHFVHLAGKSTLKDWKRAIRLGGI 154
Query: 524 TLGELLKSG 532
L +++ SG
Sbjct: 155 MLRKMMDSG 163
>gi|13435375 glucocorticoid modulatory element binding protein 1
isoform 2 [Homo sapiens]
Length = 563
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 465 PVTCGEAKGI-LYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGM 523
P+TCGE+K I L+KK + G +VKC++ D ++P F K+WKR IR G+
Sbjct: 86 PITCGESKAILLWKKFVCPGINVKCVKFND-QLISPKHFVHLAGKSTLKDWKRAIRLGGI 144
Query: 524 TLGELLKSG 532
L +++ SG
Sbjct: 145 MLRKMMDSG 153
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 47.4 bits (111), Expect = 3e-05
Identities = 50/213 (23%), Positives = 87/213 (40%), Gaps = 19/213 (8%)
Query: 171 SESPSPSDPVLPLPALIQEGRSTSVTN-DKLTSKMNAEEDSEEMPSLLTSTVQVASDNLI 229
S SPSP P+ + S S + K S A E E+ P L +V+V
Sbjct: 177 SRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKE---- 232
Query: 230 PQIRDKEDPQEMPHSPLGS-MPEIRDNSPEPNDPEEPQEVSSTP-SDKKGKKRKRC---- 283
P +++ ++ P +PE ++ SPE N +E ++ + P S + K R R
Sbjct: 233 PSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRS 292
Query: 284 -IWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTEC 342
+ P+RRH+ +S ++ R P++ R +++R+
Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP-------PPRHRRSRSPV 345
Query: 343 ARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVT 375
R+ RS + G+S + RS+ P P + T
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Score = 39.7 bits (91), Expect = 0.007
Identities = 69/288 (23%), Positives = 112/288 (38%), Gaps = 55/288 (19%)
Query: 86 SQINLREYPNLVTIYRSFKRVGASYERQSRDTPILLEAPTGLAEGSSLHTPLALPPPQPP 145
S + R P+L + +R G+S R +R+ +P + + H+P P P+ P
Sbjct: 646 SPVTKRRSPSLSSKHRK----GSSPSRSTREA----RSP----QPNKRHSPS--PRPRAP 691
Query: 146 QPSCSPCAPRVSEPGTSSQQSDEILSESPSPSD-PV-----LPLPALIQEGRSTSVTNDK 199
Q S SP P V +SS Q +SPSPS P+ P P I++ S S + +
Sbjct: 692 QTSSSP--PPVRRGASSSPQR----RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR 745
Query: 200 LTSKMNAEEDSEE----MPSLLTSTV--QVASDNLIPQIRDKEDPQEMPHSPLGSMPEIR 253
S + S E P S V Q S N P + P + SP S
Sbjct: 746 RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV-----PVKKAKSPTPS----- 795
Query: 254 DNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKS----------LPGGTAS 303
+ P +D E + DKK KK K+ ++HKK+ P A+
Sbjct: 796 PSPPRNSDQEGGGKKKKKKKDKKHKKDKK---HKKHKKHKKEKAVAAAAAAAVTPAAIAA 852
Query: 304 SRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEI 351
+ + ++ P+K+ +S ++ + R + R R ++
Sbjct: 853 ATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQV 900
Score = 32.7 bits (73), Expect = 0.88
Identities = 35/151 (23%), Positives = 63/151 (41%), Gaps = 11/151 (7%)
Query: 312 LKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTP 371
+K+ D+ K+D S+ E R +++R+ RKSRS +S + ++ + S
Sbjct: 144 MKKQDEDKDKRDKEEKESSREKR-ERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPR 202
Query: 372 RRVTQGAASPGHGIQEKLQVVD----KVTQRKDDSTWNSEVMMRVQK------ARTKCAR 421
R + SP +EK + KV + ++ +++V K +
Sbjct: 203 HRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE 262
Query: 422 KSRSKEKKKEKDICSSSKRRFQKNIHRRGKP 452
K+ KEK+KEK S R ++ R P
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSP 293
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 45.8 bits (107), Expect = 1e-04
Identities = 51/222 (22%), Positives = 84/222 (37%), Gaps = 27/222 (12%)
Query: 274 DKKGKKRKRCIW-------STPKRRHKKKSLP-GGTASSRHGIQKKLKRVDQVPQKKDDS 325
DK G +R+R S + RH +KS G++ S H + R + K S
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 326 TCNSTVETRAQKARTECARKSRSEEIIDGTSEM--------------NEGKRSQKTPSTP 371
S ++ +K+R+ KSRS G S N GK ++PS
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 372 RRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKE 431
+ ++ + QE+ +K + + ++R+K +SRS+ + K
Sbjct: 295 KSKSKSRSRS----QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
Query: 432 KDICSSSKR-RFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAK 472
KD KR R + R + KS+ SK G +K
Sbjct: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
Score = 35.8 bits (81), Expect = 0.10
Identities = 53/247 (21%), Positives = 98/247 (39%), Gaps = 37/247 (14%)
Query: 235 KEDPQEMPHSPLGSMPEIRDNSPEP--NDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRH 292
KE + HS S + +D + E N+ + S +PS K K + R +
Sbjct: 252 KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEE 311
Query: 293 KKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQ---KARTECARKSRSE 349
+K+ G+ S +K L++ + K S S ++++ K R +SRS
Sbjct: 312 EKR----GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR 367
Query: 350 EIIDGTSEMNE---GKRSQKTPSTPRRVTQG-----AASPGHGI-QEKLQVVDKVTQRK- 399
SE + KR K S+ ++ + + SP + +E+ + +QR+
Sbjct: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREG 427
Query: 400 ----DDSTWNSEVMMRVQ-------------KARTKCARKSRSKEKKKEKDICSSSKRRF 442
+++ N E R + ++R+K A K+RS+ K + + S S R
Sbjct: 428 RGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS-ASRSPSRS 486
Query: 443 QKNIHRR 449
+ H R
Sbjct: 487 RSRSHSR 493
Score = 32.7 bits (73), Expect = 0.88
Identities = 46/194 (23%), Positives = 77/194 (39%), Gaps = 39/194 (20%)
Query: 276 KGKKRKRCI----WSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTV 331
KG+K + I +S KR +K L G + R K++ V+ P + + + +
Sbjct: 137 KGRKNEGVIEFVSYSDMKRALEK--LDGTEVNGR-----KIRLVEDKPGSRRRRSYSRSR 189
Query: 332 ETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQV 391
++R+ +RKSRS G+S+ + K ++ S R
Sbjct: 190 SHSRSRSRSRHSRKSRSR---SGSSKSSHSKSRSRSRSGSR------------------- 227
Query: 392 VDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK--NIHRR 449
++ K S S + +K+R+ KSRS+ K S + +K N
Sbjct: 228 ----SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 450 GKPKSDTVDFHCSK 463
GKPKS + H SK
Sbjct: 284 GKPKSRSPSRHKSK 297
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 10/204 (4%)
Query: 246 LGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGK--KRKRCIWSTPKRRHKKKSLPGGTAS 303
L PE+ D + E + EE EVS S K K+K+ + ++HK S
Sbjct: 9 LREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKK 68
Query: 304 SRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQK-ARTECARKSRSEEIIDGTSEMNEGK 362
+H + K + ++ D + T+ A E K R+ + +E+ EGK
Sbjct: 69 HKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGK 128
Query: 363 RSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARK 422
S + QG S G +E+ ++ +K ST +S +++ K K
Sbjct: 129 ----VQSGMGLILQGYES---GSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTK 181
Query: 423 SRSKEKKKEKDICSSSKRRFQKNI 446
RSK + KE+ S K++ + I
Sbjct: 182 KRSKSRSKERTRHRSDKKKSKGGI 205
Score = 29.6 bits (65), Expect = 7.5
Identities = 42/211 (19%), Positives = 86/211 (40%), Gaps = 21/211 (9%)
Query: 247 GSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRH 306
G + +++ + E + S + K + ++ T +RR ++K G A S
Sbjct: 203 GGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKI---GKARSPT 259
Query: 307 GIQKKLKRVDQVPQKKDDSTCN-STVETRAQKARTECA-------RKSRSEEIIDGTSEM 358
+ K++ + +K N S R +K+R+ R+SRS+E SE
Sbjct: 260 DDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSET 319
Query: 359 NEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTK 418
++ K+ K+PS AS G + + + +R+ S + + +++R+
Sbjct: 320 DKEKKPIKSPSKD-------ASSGKENRSPSRRPGRSPKRRSLSPKPRD---KSRRSRSP 369
Query: 419 CARKSRSKEKKKEKDICSSSKRRFQKNIHRR 449
RSK+ K S +R +++ R+
Sbjct: 370 LLNDRRSKQSKSPSRTLSPGRRAKSRSLERK 400
>gi|6912568 glucocorticoid modulatory element binding protein 2
[Homo sapiens]
Length = 530
Score = 45.8 bits (107), Expect = 1e-04
Identities = 23/71 (32%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Query: 465 PVTCGEAKG-ILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGM 523
P+TCG+++ ++++K + G +VKC++ ++ ++P EF K+WKR IR G+
Sbjct: 93 PITCGDSRANLIWRKFVCPGINVKCVQYDEHV-ISPKEFVHLAGKSTLKDWKRAIRMNGI 151
Query: 524 TLGELLKSGLL 534
L +++ SG L
Sbjct: 152 MLRKIMDSGEL 162
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/309 (22%), Positives = 113/309 (36%), Gaps = 39/309 (12%)
Query: 135 TPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRS-- 192
TP P P +P+ P P+ P T + L E P+P+ P P P + +
Sbjct: 619 TPKGTAPTTPKEPA--PTTPKEPAPTTPKGTAPTTLKE-PAPTTPKKPAPKELAPTTTKG 675
Query: 193 -TSVTNDKL------------------TSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIR 233
TS T+DK T+ + E P TS V + P
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 735
Query: 234 DKEDPQEMPHSPLGSMPEIRDNSP-EPNDPEEPQEVSSTP---SDKKGKKRKRCIWSTPK 289
K + P P+ +NSP EP P ++ P + K K +R + +TP+
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795
Query: 290 RRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNST-VETRAQKARTECARKSRS 348
+ TA++ + K Q +T ++T + K T + + +
Sbjct: 796 TTTAAPKMTKETATTTEKTTES-KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 854
Query: 349 EEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEV 408
++ I T MN+ + + K R A +P K Q K +K ST +
Sbjct: 855 KKTITTTEIMNKPEETAKPKD--RATNSKATTP------KPQKPTK-APKKPTSTKKPKT 905
Query: 409 MMRVQKART 417
M RV+K +T
Sbjct: 906 MPRVRKPKT 914
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/271 (22%), Positives = 91/271 (33%), Gaps = 35/271 (12%)
Query: 123 APTGLAEGSSLHTPLALPP-PQPPQPSCSPCAPRVS-EPGTSSQQSDEILSESPSPSDPV 180
APT E + T P P+ P P+ + AP + EP ++ +S + PSP+
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424
Query: 181 LPLPALIQEGRST-----SVTNDK-------------LTSKMNAEEDSEEMPSLLTSTVQ 222
P P +E T + T K T K E P+ T
Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 484
Query: 223 VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
L P +K P P P + PE P PEEP +TP + K
Sbjct: 485 TTPKKLTPTTPEKLAP-TTPEKPAPTTPE----ELAPTTPEEP--TPTTPEEPAPTTPKA 537
Query: 283 CIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTEC 342
+TPK P T + P++ +T T T ++
Sbjct: 538 AAPNTPKE-------PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 590
Query: 343 ARKSRSEEIIDGTSEMNEGKRSQK-TPSTPR 372
+K +E+ T++ K P+TP+
Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Score = 36.6 bits (83), Expect = 0.061
Identities = 60/279 (21%), Positives = 96/279 (34%), Gaps = 49/279 (17%)
Query: 117 TPILLEAPTGLAE----GSSLHTPLALPP----------PQPPQPSCSPCAPRV-SEPGT 161
T +L PT AE G +L TP P P+ P P+ AP EP
Sbjct: 190 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 162 SSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTV 221
++ +S + P+P+ P P +E T+ T+ +A +E P+ T
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTT--- 305
Query: 222 QVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEP-----QEVSSTPSDKK 276
K+ P P + P+ P P P+EP + +TP +
Sbjct: 306 ------------PKKPAPTTPKEPAPTTPK----EPTPTTPKEPAPTTKEPAPTTPKEPA 349
Query: 277 GKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQ 336
K+ +TPK P T + P++ +T S T +
Sbjct: 350 PTAPKKPAPTTPKE-------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 337 KA--RTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRR 373
A T+ A + E T E + P+TP++
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 441
Score = 30.4 bits (67), Expect = 4.4
Identities = 43/229 (18%), Positives = 80/229 (34%), Gaps = 24/229 (10%)
Query: 117 TPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSP 176
TP + PT + + TP P P SP P V T + E+ + +
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 177 S---------DPVLPLPALIQEGRST---------SVTNDKLTSKMNAEEDSEEMPSLLT 218
+ + P + +E +T + T ++TS + ++ +L T
Sbjct: 785 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844
Query: 219 STVQ---VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDK 275
+T+ + I P+E P + +P+P P + + ++
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPEETA-KPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 903
Query: 276 KGKKRKRCIWSTPKRRHKKKSLPGGTASSR--HGIQKKLKRVDQVPQKK 322
K R R +TP R ++P +SR + + R +Q P K
Sbjct: 904 KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 952
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/309 (22%), Positives = 113/309 (36%), Gaps = 39/309 (12%)
Query: 135 TPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRS-- 192
TP P P +P+ P P+ P T + L E P+P+ P P P + +
Sbjct: 660 TPKGTAPTTPKEPA--PTTPKEPAPTTPKGTAPTTLKE-PAPTTPKKPAPKELAPTTTKG 716
Query: 193 -TSVTNDKL------------------TSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIR 233
TS T+DK T+ + E P TS V + P
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 776
Query: 234 DKEDPQEMPHSPLGSMPEIRDNSP-EPNDPEEPQEVSSTP---SDKKGKKRKRCIWSTPK 289
K + P P+ +NSP EP P ++ P + K K +R + +TP+
Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836
Query: 290 RRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNST-VETRAQKARTECARKSRS 348
+ TA++ + K Q +T ++T + K T + + +
Sbjct: 837 TTTAAPKMTKETATTTEKTTES-KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 895
Query: 349 EEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEV 408
++ I T MN+ + + K R A +P K Q K +K ST +
Sbjct: 896 KKTITTTEIMNKPEETAKPKD--RATNSKATTP------KPQKPTK-APKKPTSTKKPKT 946
Query: 409 MMRVQKART 417
M RV+K +T
Sbjct: 947 MPRVRKPKT 955
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/271 (22%), Positives = 91/271 (33%), Gaps = 35/271 (12%)
Query: 123 APTGLAEGSSLHTPLALPP-PQPPQPSCSPCAPRVS-EPGTSSQQSDEILSESPSPSDPV 180
APT E + T P P+ P P+ + AP + EP ++ +S + PSP+
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465
Query: 181 LPLPALIQEGRST-----SVTNDK-------------LTSKMNAEEDSEEMPSLLTSTVQ 222
P P +E T + T K T K E P+ T
Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 525
Query: 223 VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
L P +K P P P + PE P PEEP +TP + K
Sbjct: 526 TTPKKLTPTTPEKLAP-TTPEKPAPTTPE----ELAPTTPEEP--TPTTPEEPAPTTPKA 578
Query: 283 CIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTEC 342
+TPK P T + P++ +T T T ++
Sbjct: 579 AAPNTPKE-------PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 631
Query: 343 ARKSRSEEIIDGTSEMNEGKRSQK-TPSTPR 372
+K +E+ T++ K P+TP+
Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Score = 36.6 bits (83), Expect = 0.061
Identities = 60/279 (21%), Positives = 96/279 (34%), Gaps = 49/279 (17%)
Query: 117 TPILLEAPTGLAE----GSSLHTPLALPP----------PQPPQPSCSPCAPRV-SEPGT 161
T +L PT AE G +L TP P P+ P P+ AP EP
Sbjct: 231 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 162 SSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTV 221
++ +S + P+P+ P P +E T+ T+ +A +E P+ T
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTT--- 346
Query: 222 QVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEP-----QEVSSTPSDKK 276
K+ P P + P+ P P P+EP + +TP +
Sbjct: 347 ------------PKKPAPTTPKEPAPTTPK----EPTPTTPKEPAPTTKEPAPTTPKEPA 390
Query: 277 GKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQ 336
K+ +TPK P T + P++ +T S T +
Sbjct: 391 PTAPKKPAPTTPKE-------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 337 KA--RTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRR 373
A T+ A + E T E + P+TP++
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 482
Score = 30.4 bits (67), Expect = 4.4
Identities = 43/229 (18%), Positives = 80/229 (34%), Gaps = 24/229 (10%)
Query: 117 TPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSP 176
TP + PT + + TP P P SP P V T + E+ + +
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Query: 177 S---------DPVLPLPALIQEGRST---------SVTNDKLTSKMNAEEDSEEMPSLLT 218
+ + P + +E +T + T ++TS + ++ +L T
Sbjct: 826 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 885
Query: 219 STVQ---VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDK 275
+T+ + I P+E P + +P+P P + + ++
Sbjct: 886 TTLAPKVTTTKKTITTTEIMNKPEETA-KPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 944
Query: 276 KGKKRKRCIWSTPKRRHKKKSLPGGTASSR--HGIQKKLKRVDQVPQKK 322
K R R +TP R ++P +SR + + R +Q P K
Sbjct: 945 KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 993
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/309 (22%), Positives = 113/309 (36%), Gaps = 39/309 (12%)
Query: 135 TPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRS-- 192
TP P P +P+ P P+ P T + L E P+P+ P P P + +
Sbjct: 712 TPKGTAPTTPKEPA--PTTPKEPAPTTPKGTAPTTLKE-PAPTTPKKPAPKELAPTTTKG 768
Query: 193 -TSVTNDKL------------------TSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIR 233
TS T+DK T+ + E P TS V + P
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828
Query: 234 DKEDPQEMPHSPLGSMPEIRDNSP-EPNDPEEPQEVSSTP---SDKKGKKRKRCIWSTPK 289
K + P P+ +NSP EP P ++ P + K K +R + +TP+
Sbjct: 829 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 888
Query: 290 RRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNST-VETRAQKARTECARKSRS 348
+ TA++ + K Q +T ++T + K T + + +
Sbjct: 889 TTTAAPKMTKETATTTEKTTES-KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 947
Query: 349 EEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEV 408
++ I T MN+ + + K R A +P K Q K +K ST +
Sbjct: 948 KKTITTTEIMNKPEETAKPKD--RATNSKATTP------KPQKPTK-APKKPTSTKKPKT 998
Query: 409 MMRVQKART 417
M RV+K +T
Sbjct: 999 MPRVRKPKT 1007
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/271 (22%), Positives = 91/271 (33%), Gaps = 35/271 (12%)
Query: 123 APTGLAEGSSLHTPLALPP-PQPPQPSCSPCAPRVS-EPGTSSQQSDEILSESPSPSDPV 180
APT E + T P P+ P P+ + AP + EP ++ +S + PSP+
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517
Query: 181 LPLPALIQEGRST-----SVTNDK-------------LTSKMNAEEDSEEMPSLLTSTVQ 222
P P +E T + T K T K E P+ T
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 577
Query: 223 VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
L P +K P P P + PE P PEEP +TP + K
Sbjct: 578 TTPKKLTPTTPEKLAP-TTPEKPAPTTPE----ELAPTTPEEP--TPTTPEEPAPTTPKA 630
Query: 283 CIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTEC 342
+TPK P T + P++ +T T T ++
Sbjct: 631 AAPNTPKE-------PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 683
Query: 343 ARKSRSEEIIDGTSEMNEGKRSQK-TPSTPR 372
+K +E+ T++ K P+TP+
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Score = 36.6 bits (83), Expect = 0.061
Identities = 60/279 (21%), Positives = 96/279 (34%), Gaps = 49/279 (17%)
Query: 117 TPILLEAPTGLAE----GSSLHTPLALPP----------PQPPQPSCSPCAPRV-SEPGT 161
T +L PT AE G +L TP P P+ P P+ AP EP
Sbjct: 283 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 342
Query: 162 SSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTV 221
++ +S + P+P+ P P +E T+ T+ +A +E P+ T
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTT--- 398
Query: 222 QVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEP-----QEVSSTPSDKK 276
K+ P P + P+ P P P+EP + +TP +
Sbjct: 399 ------------PKKPAPTTPKEPAPTTPK----EPTPTTPKEPAPTTKEPAPTTPKEPA 442
Query: 277 GKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQ 336
K+ +TPK P T + P++ +T S T +
Sbjct: 443 PTAPKKPAPTTPKE-------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495
Query: 337 KA--RTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRR 373
A T+ A + E T E + P+TP++
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 534
Score = 30.4 bits (67), Expect = 4.4
Identities = 43/229 (18%), Positives = 80/229 (34%), Gaps = 24/229 (10%)
Query: 117 TPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSP 176
TP + PT + + TP P P SP P V T + E+ + +
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 877
Query: 177 S---------DPVLPLPALIQEGRST---------SVTNDKLTSKMNAEEDSEEMPSLLT 218
+ + P + +E +T + T ++TS + ++ +L T
Sbjct: 878 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 937
Query: 219 STVQ---VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDK 275
+T+ + I P+E P + +P+P P + + ++
Sbjct: 938 TTLAPKVTTTKKTITTTEIMNKPEETA-KPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 996
Query: 276 KGKKRKRCIWSTPKRRHKKKSLPGGTASSR--HGIQKKLKRVDQVPQKK 322
K R R +TP R ++P +SR + + R +Q P K
Sbjct: 997 KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1045
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/309 (22%), Positives = 113/309 (36%), Gaps = 39/309 (12%)
Query: 135 TPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRS-- 192
TP P P +P+ P P+ P T + L E P+P+ P P P + +
Sbjct: 753 TPKGTAPTTPKEPA--PTTPKEPAPTTPKGTAPTTLKE-PAPTTPKKPAPKELAPTTTKG 809
Query: 193 -TSVTNDKL------------------TSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIR 233
TS T+DK T+ + E P TS V + P
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869
Query: 234 DKEDPQEMPHSPLGSMPEIRDNSP-EPNDPEEPQEVSSTP---SDKKGKKRKRCIWSTPK 289
K + P P+ +NSP EP P ++ P + K K +R + +TP+
Sbjct: 870 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 929
Query: 290 RRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNST-VETRAQKARTECARKSRS 348
+ TA++ + K Q +T ++T + K T + + +
Sbjct: 930 TTTAAPKMTKETATTTEKTTES-KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 988
Query: 349 EEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEV 408
++ I T MN+ + + K R A +P K Q K +K ST +
Sbjct: 989 KKTITTTEIMNKPEETAKPKD--RATNSKATTP------KPQKPTK-APKKPTSTKKPKT 1039
Query: 409 MMRVQKART 417
M RV+K +T
Sbjct: 1040 MPRVRKPKT 1048
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/271 (22%), Positives = 91/271 (33%), Gaps = 35/271 (12%)
Query: 123 APTGLAEGSSLHTPLALPP-PQPPQPSCSPCAPRVS-EPGTSSQQSDEILSESPSPSDPV 180
APT E + T P P+ P P+ + AP + EP ++ +S + PSP+
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558
Query: 181 LPLPALIQEGRST-----SVTNDK-------------LTSKMNAEEDSEEMPSLLTSTVQ 222
P P +E T + T K T K E P+ T
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 618
Query: 223 VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
L P +K P P P + PE P PEEP +TP + K
Sbjct: 619 TTPKKLTPTTPEKLAP-TTPEKPAPTTPE----ELAPTTPEEP--TPTTPEEPAPTTPKA 671
Query: 283 CIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTEC 342
+TPK P T + P++ +T T T ++
Sbjct: 672 AAPNTPKE-------PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 724
Query: 343 ARKSRSEEIIDGTSEMNEGKRSQK-TPSTPR 372
+K +E+ T++ K P+TP+
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Score = 36.6 bits (83), Expect = 0.061
Identities = 60/279 (21%), Positives = 96/279 (34%), Gaps = 49/279 (17%)
Query: 117 TPILLEAPTGLAE----GSSLHTPLALPP----------PQPPQPSCSPCAPRV-SEPGT 161
T +L PT AE G +L TP P P+ P P+ AP EP
Sbjct: 324 TSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAP 383
Query: 162 SSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTV 221
++ +S + P+P+ P P +E T+ T+ +A +E P+ T
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE-PAPTT--- 439
Query: 222 QVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEP-----QEVSSTPSDKK 276
K+ P P + P+ P P P+EP + +TP +
Sbjct: 440 ------------PKKPAPTTPKEPAPTTPK----EPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 277 GKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQ 336
K+ +TPK P T + P++ +T S T +
Sbjct: 484 PTAPKKPAPTTPKE-------PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536
Query: 337 KA--RTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRR 373
A T+ A + E T E + P+TP++
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 575
Score = 30.4 bits (67), Expect = 4.4
Identities = 43/229 (18%), Positives = 80/229 (34%), Gaps = 24/229 (10%)
Query: 117 TPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSP 176
TP + PT + + TP P P SP P V T + E+ + +
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 918
Query: 177 S---------DPVLPLPALIQEGRST---------SVTNDKLTSKMNAEEDSEEMPSLLT 218
+ + P + +E +T + T ++TS + ++ +L T
Sbjct: 919 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 978
Query: 219 STVQ---VASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDK 275
+T+ + I P+E P + +P+P P + + ++
Sbjct: 979 TTLAPKVTTTKKTITTTEIMNKPEETA-KPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 1037
Query: 276 KGKKRKRCIWSTPKRRHKKKSLPGGTASSR--HGIQKKLKRVDQVPQKK 322
K R R +TP R ++P +SR + + R +Q P K
Sbjct: 1038 KTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1086
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 44.3 bits (103), Expect = 3e-04
Identities = 72/337 (21%), Positives = 128/337 (37%), Gaps = 38/337 (11%)
Query: 158 EPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSV-TNDKLTSKMNAEEDSEEMPSL 216
+P S Q+ E S S + PL + G S V + +L+ + + S E+
Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDK 1607
Query: 217 LTSTVQVASDNLIPQIRDKEDPQEMPH-SPLGSMPEIRDNSPE-----PNDPEEPQEVSS 270
+ + S + P+ +P S GS + R SPE + PE P + +
Sbjct: 1608 PRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT 1667
Query: 271 TPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSR-----HGIQKKLKRVDQVPQKKDDS 325
+ + TP RR +S P T +R + + P + S
Sbjct: 1668 ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 326 TCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEG--------------KRSQKTPSTP 371
S+ E A+K+R+ R+S S TS R +KT +T
Sbjct: 1728 PSVSSPEP-AEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786
Query: 372 RRVTQGAASPGHGIQEKLQVVDKVT-QRKDDSTWNSEVMMRVQKARTKC-ARKSRSK--- 426
RR G++ +++ + +VT +R+ S ++S R + +RT R+ RS+
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846
Query: 427 -EKKKEKDICS-----SSKRRFQKNIHRRGKPKSDTV 457
+K+ + S S+ R HRR + ++ +
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLI 1883
Score = 40.4 bits (93), Expect = 0.004
Identities = 77/338 (22%), Positives = 122/338 (36%), Gaps = 56/338 (16%)
Query: 142 PQPPQPSCSPCAPR-VSEPGTSSQQS------DEILSESPSPSDPVLPLPALIQEGRSTS 194
P+ P+P+ +P + R +S TS +S D+ S +PS PA + GRS S
Sbjct: 438 PESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRS 497
Query: 195 VTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMP------------ 242
T K S + + Q + PQ R + + P
Sbjct: 498 RTPTK-----RGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552
Query: 243 ----------HSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKR----KRCIWSTP 288
HS P R S + S TP+ ++ + R +R TP
Sbjct: 553 RSRSARRGRSHS---RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
Query: 289 KRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRS 348
RR + +S SR + + + P ++ + + T R + AR+ RS
Sbjct: 610 ARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS 669
Query: 349 EEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVV------DKVTQRKDDS 402
T G+ +TP+ RR + +P G +V + QR+ S
Sbjct: 670 R---SRTPARRSGRSRSRTPA--RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
Query: 403 TWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKR 440
+SE R K+RT R+SRS + K SS+R
Sbjct: 725 GSSSE---RKNKSRTS-QRRSRSNSSPEMKKSRISSRR 758
Score = 40.0 bits (92), Expect = 0.006
Identities = 77/348 (22%), Positives = 124/348 (35%), Gaps = 43/348 (12%)
Query: 135 TPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTS 194
T LA P P SEPGT+S Q PS + P+ E +
Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQR-------PSSPETATKQPSSPYEDKDKD 341
Query: 195 VTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHSPLGSMP---- 250
T + E S P T +A R PQ + +PL P
Sbjct: 342 KKEKSATRPSPSPERSSTGPEPPAPTPLLAE-------RHGGSPQPLATTPLSQEPVNPP 394
Query: 251 ----EIRDNSPEPNDPEEPQEVS--STPSDKKGKKRKRCIWSTPKR--------RHKKKS 296
RD SP + + PQ S S+P + K R S+P+ H++ S
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 297 LPGGTASSRHGIQKKLKRVDQVPQKK-DDSTCNSTVETRAQKARTECAR---KSRSEEII 352
+ + HG K+ K P ++ S +T + ++RT R +SRS +
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514
Query: 353 DGTSEMNEGK-RSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMR 411
S G+ RS + R + S Q + + + R+ S S
Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR---SRSARRGRSHSRSPATRG 571
Query: 412 VQKARTKCAR---KSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDT 456
++RT R +SR+ +++ + + +R + RRG+ +S T
Sbjct: 572 RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619
Score = 37.0 bits (84), Expect = 0.047
Identities = 74/376 (19%), Positives = 140/376 (37%), Gaps = 29/376 (7%)
Query: 82 VTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPILLEAPT---GLAEGSSLHTPLA 138
++ + +++ R P L+ RS R S QSR T +P+ G A SL P A
Sbjct: 2387 LSAYERVSGRTSPPLLDRARS--RTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP-A 2443
Query: 139 LPPPQPPQPSC----SPCAPRVSEP--GTSSQQSDEILSESPSPSDP----VLPLPALIQ 188
P+ P PS S C + P G+ S S + + + S D +P P +
Sbjct: 2444 QDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPH 2503
Query: 189 E--GRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHSPL 246
G + T + S + A + ++E S +S+ +S + S
Sbjct: 2504 SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS-------SSSSSSSSSSSS 2556
Query: 247 GSMPEIRDNSPEPNDPEEPQE--VSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASS 304
GS + S P PE + S TP+ K+ + R TP +R ++ S ++SS
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 305 RHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRS 364
S+ +S+ + + + + ++ + + G+R
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA--SPKKPPPGERR 2674
Query: 365 QKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSR 424
++P P + + S + E+ + + + R S+ + R Q+ ++ R
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734
Query: 425 SKEKKKEKDICSSSKR 440
+E + + S R
Sbjct: 2735 RRETPSPRPMRHRSSR 2750
Score = 32.3 bits (72), Expect = 1.2
Identities = 44/219 (20%), Positives = 77/219 (35%), Gaps = 40/219 (18%)
Query: 164 QQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQV 223
+++ E +P P P +L++E S+ K K ++
Sbjct: 155 RRAREAKQPAPEPPKPY----SLVRESSSSRSPTPKQKKKKKKKDRGRR----------- 199
Query: 224 ASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRC 283
S++ P+ K+ ++ H + + SP P S S K +KR R
Sbjct: 200 -SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK--------SKRKSKDKKRKRSRS 250
Query: 284 IWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECA 343
PK R +S +ASS + + + + + T A R+
Sbjct: 251 TTPAPKSRRAHRSTSADSASSSDTSRSRSR------------SAAAKTHTTALAGRSPSP 298
Query: 344 RKSRSEEIIDGTSEMNE-GKRSQKTPSTPRRVTQGAASP 381
R E G + +E G S + PS+P T+ +SP
Sbjct: 299 ASGRRGE---GDAPFSEPGTTSTQRPSSPETATKQPSSP 334
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 43.9 bits (102), Expect = 4e-04
Identities = 59/274 (21%), Positives = 104/274 (37%), Gaps = 29/274 (10%)
Query: 188 QEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQ---IRD-KEDPQEMPH 243
+EG S ++ + AE + EE + V+ S+ + + + D K + E
Sbjct: 555 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAK 614
Query: 244 SPLGSMP-EIRDNSPEPNDPEEPQ---EVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPG 299
SP+ P E + SP P P E + V +P ++KGK PK ++K G
Sbjct: 615 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS------PVPKSPVEEK---G 665
Query: 300 GTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSE--EIIDGTSE 357
+ S+ +++K K VP+ S VE KA + E E+ + E
Sbjct: 666 KSPVSKSPVEEKAK--SPVPK--------SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKE 715
Query: 358 MNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART 417
K+ +K P + + + E + + V + T ++ +K +
Sbjct: 716 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 775
Query: 418 KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRGK 451
K + S+E+ +K S K N GK
Sbjct: 776 KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGK 809
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 43.9 bits (102), Expect = 4e-04
Identities = 59/274 (21%), Positives = 104/274 (37%), Gaps = 29/274 (10%)
Query: 188 QEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQ---IRD-KEDPQEMPH 243
+EG S ++ + AE + EE + V+ S+ + + + D K + E
Sbjct: 179 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAK 238
Query: 244 SPLGSMP-EIRDNSPEPNDPEEPQ---EVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPG 299
SP+ P E + SP P P E + V +P ++KGK PK ++K G
Sbjct: 239 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS------PVPKSPVEEK---G 289
Query: 300 GTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSE--EIIDGTSE 357
+ S+ +++K K VP+ S VE KA + E E+ + E
Sbjct: 290 KSPVSKSPVEEKAK--SPVPK--------SPVEEAKSKAEVGKGEQKEEEEKEVKEAPKE 339
Query: 358 MNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART 417
K+ +K P + + + E + + V + T ++ +K +
Sbjct: 340 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 399
Query: 418 KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRGK 451
K + S+E+ +K S K N GK
Sbjct: 400 KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGK 433
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 43.5 bits (101), Expect = 5e-04
Identities = 65/300 (21%), Positives = 115/300 (38%), Gaps = 34/300 (11%)
Query: 114 SRDTPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPG-TSSQQSDEILSE 172
S D+ +L +G++ GS H L P Q +P S PR+ +PG S+ ++ +I SE
Sbjct: 2129 SSDSDSILSLKSGISLGSPFH----LTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESE 2184
Query: 173 SPSPSDPVLPLPALIQ-EGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQV------AS 225
S +LI + RS S + ++ + A MPS+ + S
Sbjct: 2185 SKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQA-----NMPSISRGRTMIHIPGVRNS 2239
Query: 226 DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTP-------SDKKGK 278
+ + K P + P S S + SP P E+S K
Sbjct: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP 2299
Query: 279 KRKRCIWSTPKRRHKKK-----SLPGGTASS--RHGIQKKLKRVDQVPQKKDDSTCNSTV 331
R STP R ++ PG + S R+GI ++ Q+P+ ST ++
Sbjct: 2300 SRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPP-NKLSQLPRTSSPSTASTKS 2358
Query: 332 ETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQV 391
+ + T R+ + + T ++ S + + Q + G+G +K+++
Sbjct: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ--MNNGNGANKKVEL 2416
Score = 31.2 bits (69), Expect = 2.6
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 171 SESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIP 230
++SPS S P + T + + TS + DS E S+ +S ++
Sbjct: 1358 AKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSL--DSFESRSIASSVQSEPCSGMVS 1415
Query: 231 QIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
I P ++P SP +MP R +P P P+ Q P +K KR
Sbjct: 1416 GIIS---PSDLPDSPGQTMPPSRSKTPPP-PPQTAQTKREVPKNKAPTAEKR 1463
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 43.5 bits (101), Expect = 5e-04
Identities = 65/300 (21%), Positives = 115/300 (38%), Gaps = 34/300 (11%)
Query: 114 SRDTPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPG-TSSQQSDEILSE 172
S D+ +L +G++ GS H L P Q +P S PR+ +PG S+ ++ +I SE
Sbjct: 2129 SSDSDSILSLKSGISLGSPFH----LTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESE 2184
Query: 173 SPSPSDPVLPLPALIQ-EGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQV------AS 225
S +LI + RS S + ++ + A MPS+ + S
Sbjct: 2185 SKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQA-----NMPSISRGRTMIHIPGVRNS 2239
Query: 226 DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTP-------SDKKGK 278
+ + K P + P S S + SP P E+S K
Sbjct: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP 2299
Query: 279 KRKRCIWSTPKRRHKKK-----SLPGGTASS--RHGIQKKLKRVDQVPQKKDDSTCNSTV 331
R STP R ++ PG + S R+GI ++ Q+P+ ST ++
Sbjct: 2300 SRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPP-NKLSQLPRTSSPSTASTKS 2358
Query: 332 ETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQV 391
+ + T R+ + + T ++ S + + Q + G+G +K+++
Sbjct: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ--MNNGNGANKKVEL 2416
Score = 31.2 bits (69), Expect = 2.6
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 171 SESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIP 230
++SPS S P + T + + TS + DS E S+ +S ++
Sbjct: 1358 AKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSL--DSFESRSIASSVQSEPCSGMVS 1415
Query: 231 QIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
I P ++P SP +MP R +P P P+ Q P +K KR
Sbjct: 1416 GIIS---PSDLPDSPGQTMPPSRSKTPPP-PPQTAQTKREVPKNKAPTAEKR 1463
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 43.5 bits (101), Expect = 5e-04
Identities = 65/300 (21%), Positives = 115/300 (38%), Gaps = 34/300 (11%)
Query: 114 SRDTPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPG-TSSQQSDEILSE 172
S D+ +L +G++ GS H L P Q +P S PR+ +PG S+ ++ +I SE
Sbjct: 2129 SSDSDSILSLKSGISLGSPFH----LTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESE 2184
Query: 173 SPSPSDPVLPLPALIQ-EGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQV------AS 225
S +LI + RS S + ++ + A MPS+ + S
Sbjct: 2185 SKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQA-----NMPSISRGRTMIHIPGVRNS 2239
Query: 226 DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTP-------SDKKGK 278
+ + K P + P S S + SP P E+S K
Sbjct: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP 2299
Query: 279 KRKRCIWSTPKRRHKKK-----SLPGGTASS--RHGIQKKLKRVDQVPQKKDDSTCNSTV 331
R STP R ++ PG + S R+GI ++ Q+P+ ST ++
Sbjct: 2300 SRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPP-NKLSQLPRTSSPSTASTKS 2358
Query: 332 ETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQV 391
+ + T R+ + + T ++ S + + Q + G+G +K+++
Sbjct: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ--MNNGNGANKKVEL 2416
Score = 31.2 bits (69), Expect = 2.6
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 171 SESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIP 230
++SPS S P + T + + TS + DS E S+ +S ++
Sbjct: 1358 AKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSL--DSFESRSIASSVQSEPCSGMVS 1415
Query: 231 QIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKR 282
I P ++P SP +MP R +P P P+ Q P +K KR
Sbjct: 1416 GIIS---PSDLPDSPGQTMPPSRSKTPPP-PPQTAQTKREVPKNKAPTAEKR 1463
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/204 (21%), Positives = 87/204 (42%), Gaps = 6/204 (2%)
Query: 242 PHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGT 301
P + G EIR+ E +E ++ S++K ++R+R KR +K+
Sbjct: 28 PCTQPGWQSEIREREREIETRKEGKK--ERESERKKERRER---EKRKREREKERKRERG 82
Query: 302 ASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEG 361
+ G +KK +R + +++ ++ E R +K + E R S+ + + E
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 362 KRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCAR 421
+R ++ R + +E+ QV +K +RK+ + R +K R K
Sbjct: 143 ERKERERKKEEREKERERKERKK-RERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Query: 422 KSRSKEKKKEKDICSSSKRRFQKN 445
+ +E+KKE+ K+ QK+
Sbjct: 202 RKERRERKKERKKKEERKKERQKD 225
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 43.5 bits (101), Expect = 5e-04
Identities = 62/271 (22%), Positives = 102/271 (37%), Gaps = 44/271 (16%)
Query: 141 PPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKL 200
P +PP S P AP+ +S S SES S SD S+S + +
Sbjct: 441 PEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSD-------------SSSDSESES 487
Query: 201 TSKMNAEEDSEEMPS---LLTSTVQVASDNLIPQIRDKEDPQEMPHS--PLGSMPEIRDN 255
+S + E + E P+ +T + DN + ++ P E P S P PE + +
Sbjct: 488 SSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGS 547
Query: 256 SPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRV 315
S E + S P K K R + P+ H PG + + Q+
Sbjct: 548 SDSATSQEHSE--SKDPPPKSSSKAPR---APPEAPH-----PGKRSCQKSPAQQ----- 592
Query: 316 DQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSE---MNEGKRSQKTPSTPR 372
+ PQ++ TV T+ K + + ++ S + G E + G R Q + P+
Sbjct: 593 -EPPQRQ-------TVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPK 644
Query: 373 RVTQGAASPGHGIQEKLQVVDKVTQRKDDST 403
T+G + K V ++K S+
Sbjct: 645 VKTKGRPRAAASNEPKPAVPPSSEKKKHKSS 675
Score = 33.9 bits (76), Expect = 0.40
Identities = 79/366 (21%), Positives = 139/366 (37%), Gaps = 46/366 (12%)
Query: 138 ALPPPQP-PQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVT 196
A PP Q P PS + + + T+ + + ++PS S + PLP ++ R +
Sbjct: 267 AQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLP---EDYRQQTFE 323
Query: 197 NDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHS---PLGSM--PE 251
L A+ +MPS +V+ N + + +E +EM HS PL ++ P
Sbjct: 324 KTDLKVPAKAKLTKLKMPS---QSVEQTYSNEVHCV--EEILKEMTHSWPPPLTAIHTPS 378
Query: 252 IRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQ-- 309
+ S P ++ Q VSS ++K + T + H S G ++ +Q
Sbjct: 379 TAEPSKFPFPTKDSQHVSSVTQNQKQ-------YDTSSKTH-SNSQQGTSSMLEDDLQLS 430
Query: 310 -KKLKRVDQVPQKKDDSTC-NSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKT 367
+ +Q P+K S+ S ++ + + + + SE D S + S +
Sbjct: 431 DSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSS 490
Query: 368 PSTPRR-VTQGAASPGHGIQEKLQV---VDKVTQ---------------RKDDSTWNSEV 408
S + A P K Q+ + KV+Q R +S +S+
Sbjct: 491 DSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550
Query: 409 MMRVQKARTK-CARKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVT 467
+ + +K KS SK + + KR QK+ ++ P+ TV K PV
Sbjct: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
Query: 468 CGEAKG 473
G
Sbjct: 611 ASARAG 616
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 43.5 bits (101), Expect = 5e-04
Identities = 71/302 (23%), Positives = 106/302 (35%), Gaps = 31/302 (10%)
Query: 97 VTIYRSFKRVGASYERQSRDTPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRV 156
++I+ S + G E + EAP A+ + L LPPP P SP
Sbjct: 268 LSIHVSVPQSGLRREEPDLQPQLASEAPRRPAQPPPSKSAL-LPPPSPRVGKRSP----- 321
Query: 157 SEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSL 216
PG +Q + S +PVLP +E R + + AE + S
Sbjct: 322 --PGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAESRPQTPLSE 379
Query: 217 LTSTVQVA--SDNLI---PQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSST 271
+ + S L+ +I DK E L E D+ P P P P +
Sbjct: 380 ASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSL----ERSDSPPAPLRPWVP--LRKA 433
Query: 272 PSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQ-VPQKKDDSTCNST 330
S ++ K + W TP ++ PG A R Q+K +D+ Q+ S
Sbjct: 434 RSLEQPKSERGAPWGTPGASQEELRAPGSVAERRRLFQQKAASLDERTRQRSPASDLELR 493
Query: 331 VETRAQKARTECARKS--RSEEIIDGTSEMNEGKRS---------QKTPSTPRRVTQGAA 379
+ R +R+ RS E + T + R TP T R V+ AA
Sbjct: 494 FAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAA 553
Query: 380 SP 381
P
Sbjct: 554 QP 555
Score = 29.3 bits (64), Expect = 9.8
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
Query: 131 SSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDP 179
+SL PLA P PP + SP +P P SQ + + P P P
Sbjct: 2801 TSLAPPLAPAAPTPPSVTVSPSSP----PTPPSQALSSLKAVGPPPQTP 2845
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,965,863
Number of Sequences: 37866
Number of extensions: 1299340
Number of successful extensions: 10957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 727
Number of HSP's that attempted gapping in prelim test: 8389
Number of HSP's gapped (non-prelim): 2739
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.