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Search of human proteins with 190343006
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190343006 SP110 nuclear body protein isoform c [Homo
sapiens]
(713 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 1465 0.0
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens] 1399 0.0
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens] 1070 0.0
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 358 1e-98
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 318 1e-86
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 306 3e-83
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens] 200 3e-51
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 104 3e-22
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 104 3e-22
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 98 2e-20
gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens] 97 7e-20
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 93 7e-19
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 82 2e-15
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] 76 1e-13
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens] 65 2e-10
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 61 4e-09
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens] 58 3e-08
gi|38016945 deformed epidermal autoregulatory factor 1 [Homo sap... 56 1e-07
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 55 3e-07
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 54 7e-07
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 53 9e-07
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 53 9e-07
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 53 9e-07
gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens] 53 1e-06
gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens] 53 1e-06
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 50 6e-06
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] 50 9e-06
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 50 9e-06
gi|38788260 bromodomain PHD finger transcription factor isoform ... 49 2e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ... 49 2e-05
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 1465 bits (3793), Expect = 0.0
Identities = 713/713 (100%), Positives = 713/713 (100%)
Query: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP
Sbjct: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
Query: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL
Sbjct: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
Query: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV
Sbjct: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
Query: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE
Sbjct: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
Query: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG
Sbjct: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
Query: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE
Sbjct: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
Query: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA
Sbjct: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
Query: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM
Sbjct: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
Query: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVC 540
KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVC
Sbjct: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVC 540
Query: 541 CQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQ 600
CQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQ
Sbjct: 541 CQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQ 600
Query: 601 PQDQLKCEFLLLKAYCHPQSSFFTGIPFNIRDYGEPFQEAMWLDLVKERLITEMYTVAWF 660
PQDQLKCEFLLLKAYCHPQSSFFTGIPFNIRDYGEPFQEAMWLDLVKERLITEMYTVAWF
Sbjct: 601 PQDQLKCEFLLLKAYCHPQSSFFTGIPFNIRDYGEPFQEAMWLDLVKERLITEMYTVAWF 660
Query: 661 VRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP 713
VRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP
Sbjct: 661 VRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP 713
>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
Length = 689
Score = 1399 bits (3622), Expect = 0.0
Identities = 689/713 (96%), Positives = 689/713 (96%), Gaps = 24/713 (3%)
Query: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP
Sbjct: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
Query: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL
Sbjct: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
Query: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV
Sbjct: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
Query: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE
Sbjct: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
Query: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG
Sbjct: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
Query: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE
Sbjct: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
Query: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA
Sbjct: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
Query: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM
Sbjct: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
Query: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVC 540
KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVC
Sbjct: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVC 540
Query: 541 CQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQ 600
CQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQ
Sbjct: 541 CQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQ 600
Query: 601 PQDQLKCEFLLLKAYCHPQSSFFTGIPFNIRDYGEPFQEAMWLDLVKERLITEMYTVAWF 660
PQDQL IRDYGEPFQEAMWLDLVKERLITEMYTVAWF
Sbjct: 601 PQDQL------------------------IRDYGEPFQEAMWLDLVKERLITEMYTVAWF 636
Query: 661 VRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP 713
VRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP
Sbjct: 637 VRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP 689
>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
Length = 549
Score = 1070 bits (2767), Expect = 0.0
Identities = 530/530 (100%), Positives = 530/530 (100%)
Query: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP
Sbjct: 1 MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIP 60
Query: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL
Sbjct: 61 VSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYERQSRDTPIL 120
Query: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV
Sbjct: 121 LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPV 180
Query: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE
Sbjct: 181 LPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQE 240
Query: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG
Sbjct: 241 MPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGG 300
Query: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE
Sbjct: 301 TASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNE 360
Query: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA
Sbjct: 361 GKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCA 420
Query: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM
Sbjct: 421 RKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKM 480
Query: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK 530
KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK
Sbjct: 481 KHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLK 530
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 358 bits (919), Expect = 1e-98
Identities = 259/841 (30%), Positives = 391/841 (46%), Gaps = 150/841 (17%)
Query: 6 RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65
R + + +F+HF K+ I+ AI K FPF EGL D +IT +M+ +S ++CRNL+PV RVV
Sbjct: 47 RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
Query: 66 HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116
+N+L++LE+TFNL +L LFS +N++EYP+L+ IY+ F+ V ER+ R
Sbjct: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
Query: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158
+ LE TG SL P + P PP+ S PC +
Sbjct: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
Query: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190
SQQ++E ++ P++ + + G
Sbjct: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
Query: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244
S SV + + E + + ASD ++ D E +P E+ S
Sbjct: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
Query: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285
S P I +++P E ND +E QE + + P +K +KR I +
Sbjct: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
Query: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345
S G S+HG ++ P ++ + + + ++ +
Sbjct: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
Query: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400
S EE+ + +S + G SQ ++ + P G+ + + +Q D
Sbjct: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
Query: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451
D NS + K R K +S R ++K + + + + + +K +RG+
Sbjct: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
Query: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496
PK + ++F S+LPVTCGE KG LYK++ K G+S KCI++ED W
Sbjct: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
Query: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRK------------------------ 532
TP EFE+EG +KNWK +IRC G TL L++ K
Sbjct: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDP 697
Query: 533 ---NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMK----RSSGS 585
NS+ CEVC + G+L CC TCPR FHE CHIP VEA + WSC FCR+K R S
Sbjct: 698 CPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPES 757
Query: 586 QQCHHVSKTLERQMQPQDQLKCEFLLLKAYCHPQSSFFTGIPFNIRDYGEPFQEAMWLDL 645
Q H S+ L RQM P++QLKCEFLLLK YC +S FF P+ R+ + Q+ MWL+
Sbjct: 758 QSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNK 817
Query: 646 VKERLITEMYT-VAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEA 704
VK L +MYT V FV+DMRL+F NHK FY+ F ++G+ ++ FEK+ +++ E
Sbjct: 818 VKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQET 877
Query: 705 N 705
+
Sbjct: 878 S 878
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 318 bits (814), Expect = 1e-86
Identities = 212/598 (35%), Positives = 298/598 (49%), Gaps = 69/598 (11%)
Query: 153 APRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEE 212
+P + T ++ ++ +E P + LP +EG +D + + EE E
Sbjct: 291 SPEGRDKETFDLKTPQVTNEG-EPEKGLCLLPGEGEEG------SDDCSEMCDGEEPQEA 343
Query: 213 MPSLLT-STVQVAS----DNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQE 267
SL +V S D PQ+ ++ +P++ G E D+ E D EE QE
Sbjct: 344 SSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQE 403
Query: 268 VSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTC 327
SS+ + +R S+ H + + + +Q + + +C
Sbjct: 404 ASSSLA-------RRGSVSSELENHPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSC 456
Query: 328 NSTVETR---AQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHG 384
+ +ARTE + + + +D + GK P RR +G HG
Sbjct: 457 VMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGK-----PKRKRRKKRG-----HG 506
Query: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRF 442
+ +Q+ D+S + +V+ +KA K K R +++ K + S R
Sbjct: 507 WSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAA 566
Query: 443 QKNIHRRG--KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPN 500
QK + R K K +TVDF LPVTCG KGIL+KKK++ G VKCI+ EDG W TP
Sbjct: 567 QKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPT 626
Query: 501 EFEVEGKGRNAKNWKRNIRCEGMTLGELLKR----------------------------- 531
EFE++G +KNW+ ++RC G L L++
Sbjct: 627 EFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPC 686
Query: 532 -KNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHH 590
+N DECEVC GG+L CC TC RVFHEDCHIPPVEA+R W+C FCRMK S GSQQC
Sbjct: 687 MRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMKESPGSQQCCQ 746
Query: 591 VSKTLERQMQPQDQLKCEFLLLKAYCHPQSSFFTGIP--FNIRDYGEPFQEAMWLDLVKE 648
S+ LERQM P++QLKCEFLLLK YC +SSFF IP + IR+ + +E MWLD +K+
Sbjct: 747 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKK 806
Query: 649 RLITEMY-TVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEAN 705
RL Y V FV+DMRL+F+NH+ YK DFGQ+G LEAEFEK+ K+V E N
Sbjct: 807 RLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVFAIQETN 864
Score = 117 bits (293), Expect = 4e-26
Identities = 109/375 (29%), Positives = 166/375 (44%), Gaps = 76/375 (20%)
Query: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
Query: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGASYE-------RQSRDTPILLE 122
++LE+TF S L LFS+INL YP+L IYRSF+ V + D P LL
Sbjct: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLL- 158
Query: 123 APTGLAEGS-SLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVL 181
P G E S + H + PQ S C EPG SS+ +++ D
Sbjct: 159 -PYGKQENSNACHEMDDIAVPQEALSSSPRC-----EPGFSSESCEQLALPKAGGGD-AE 211
Query: 182 PLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEM 241
P+L+ G + KL +++ E +SEEMP LL +V N
Sbjct: 212 DAPSLLPGGG----VSCKLAIQID-EGESEEMPKLLPYDTEVLESN-------------- 252
Query: 242 PHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGT 301
G + R S+ P +K+G++ R ++P++R++ K
Sbjct: 253 -----GMIDAAR-------------TYSTAPGEKQGEEEGR---NSPRKRNQDK------ 285
Query: 302 ASSRHGIQKKLKRVDQVPQKKDDSTCN---STVETRAQKARTECARKSRSEEIIDGTSEM 358
++ + P+ +D T + V + + C EE D SEM
Sbjct: 286 -----------EKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEM 334
Query: 359 NEGKRSQKTPSTPRR 373
+G+ Q+ S+ R
Sbjct: 335 CDGEEPQEASSSLAR 349
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 306 bits (785), Expect = 3e-83
Identities = 173/406 (42%), Positives = 228/406 (56%), Gaps = 47/406 (11%)
Query: 337 KARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVT 396
+AR E + + +D + GK P RR +G HG K
Sbjct: 182 EARKESDQACGKMDTVDIANNSTLGK-----PKRKRRKKKG-----HGWSRMGTRTQKNN 231
Query: 397 QRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRG--KP 452
Q+ D+S + +++ +KA K K R +++ K + S R QK + R K
Sbjct: 232 QQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKH 291
Query: 453 KSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAK 512
K +TVDF LPVTCG KGIL+K+K++ G+ KCI+ EDG W TP EFE++G +K
Sbjct: 292 KDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSK 351
Query: 513 NWKRNIRCEGMTLGELLKR------------------------------KNSDECEVCCQ 542
NW+ ++RC G L L++ +N DECEVC
Sbjct: 352 NWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRD 411
Query: 543 GGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQPQ 602
GG+L CC TC RVFHEDCHIPPVE+++ W+C FCRMK S GSQQC S+ LERQM P+
Sbjct: 412 GGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPE 471
Query: 603 DQLKCEFLLLKAYCHPQSSFFTGIP--FNIRDYGEPFQEAMWLDLVKERLITEMY-TVAW 659
+QLKCEFLLLK YC +SSFF IP + IR+ + +E MWLD +K+RL Y V
Sbjct: 472 EQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEG 531
Query: 660 FVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEAN 705
FV+DMRL+F+NH+ YK DFGQ+GL LEAEFEKD K+V E N
Sbjct: 532 FVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETN 577
Score = 119 bits (298), Expect = 1e-26
Identities = 56/109 (51%), Positives = 82/109 (75%), Gaps = 5/109 (4%)
Query: 1 MFTMTRAMEEAL-----FQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEAC 55
+FT + ++E L F+HF KL I+ AI K FPF EGL D +IT +M+ +S ++C
Sbjct: 37 LFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSC 96
Query: 56 RNLIPVSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFK 104
RNL+PV RVV+N+L++LE+TFNLS+L LFS++N++EYP+L+ IY+SFK
Sbjct: 97 RNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFK 145
>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
Length = 879
Score = 200 bits (509), Expect = 3e-51
Identities = 172/636 (27%), Positives = 276/636 (43%), Gaps = 118/636 (18%)
Query: 6 RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65
R + + +F+HF K+ I+ AI K FPF EGL D +IT +M+ +S ++CRNL+PV RVV
Sbjct: 47 RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
Query: 66 HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116
+N+L++LE+TFNL +L LFS +N++EYP+L+ IY+ F+ V ER+ R
Sbjct: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
Query: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158
+ LE TG SL P + P PP+ S PC +
Sbjct: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
Query: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190
SQQ++E ++ P++ + + G
Sbjct: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
Query: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244
S SV + + E + + ASD ++ D E +P E+ S
Sbjct: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
Query: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285
S P I +++P E ND +E QE + + P +K +KR I +
Sbjct: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
Query: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345
S G S+HG ++ P ++ + + + ++ +
Sbjct: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
Query: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400
S EE+ + +S + G SQ ++ + P G+ + + +Q D
Sbjct: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
Query: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451
D NS + K R K +S R ++K + + + + + +K +RG+
Sbjct: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
Query: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496
PK + ++F S+LPVTCGE KG LYK++ K G+S KCI++ED W
Sbjct: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
Query: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRK 532
TP EFE+EG +KNWK +IRC G TL L++ K
Sbjct: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENK 673
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 104 bits (259), Expect = 3e-22
Identities = 67/180 (37%), Positives = 94/180 (52%), Gaps = 14/180 (7%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCR-MKRSSGSQQCHH 590
N D C VC GG+LLCC CP+VFH CH+P + W CTFCR + + C
Sbjct: 825 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 884
Query: 591 VSKTLER-------QMQPQDQLKCEFLLLKAYCHPQS-SFFTGIPFNIRDYGEPFQEAMW 642
S E+ ++ P D+ KCE LLL YCH S +F +P + DY + + M
Sbjct: 885 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMD 944
Query: 643 LDLVKERLITE--MYTVAW-FVRDMRLMFRNHKTFYKA-SDFGQVGLDLEAEFEKDLKDV 698
L +K+RL + MY+ FV D RL+F+N F + S+ G+ LE FE+ LK++
Sbjct: 945 LSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNL 1004
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 104 bits (259), Expect = 3e-22
Identities = 67/180 (37%), Positives = 94/180 (52%), Gaps = 14/180 (7%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCR-MKRSSGSQQCHH 590
N D C VC GG+LLCC CP+VFH CH+P + W CTFCR + + C
Sbjct: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850
Query: 591 VSKTLER-------QMQPQDQLKCEFLLLKAYCHPQS-SFFTGIPFNIRDYGEPFQEAMW 642
S E+ ++ P D+ KCE LLL YCH S +F +P + DY + + M
Sbjct: 851 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMD 910
Query: 643 LDLVKERLITE--MYTVAW-FVRDMRLMFRNHKTFYKA-SDFGQVGLDLEAEFEKDLKDV 698
L +K+RL + MY+ FV D RL+F+N F + S+ G+ LE FE+ LK++
Sbjct: 911 LSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNL 970
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 98.2 bits (243), Expect = 2e-20
Identities = 65/178 (36%), Positives = 92/178 (51%), Gaps = 12/178 (6%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPP-VEAKRMLWSCTFCR-MKRSSGSQQC-- 588
N D C VC GG LLCC CP+VFH CH+P + W CTFCR + + C
Sbjct: 886 NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDN 945
Query: 589 --HHVSKTLERQMQPQDQLKCEFLLLKAYCHPQS-SFFTGIPFNIRDYGEPFQEAMWLDL 645
H + + P DQ KCE LLL YCH S F +P +I +Y + ++ M L
Sbjct: 946 LQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLST 1005
Query: 646 VKERL---ITEMYTVA-WFVRDMRLMFRNHKTFYKA-SDFGQVGLDLEAEFEKDLKDV 698
VK++L ++ Y + FV D+RL+F+N + F +A S+ Q G + FE L ++
Sbjct: 1006 VKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLTEI 1063
>gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
Length = 172
Score = 96.7 bits (239), Expect = 7e-20
Identities = 50/100 (50%), Positives = 68/100 (68%)
Query: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
Query: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGAS 109
++LE+TF S L LFS+INL YP+L IYRSF+ S
Sbjct: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNENLS 139
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 93.2 bits (230), Expect = 7e-19
Identities = 61/167 (36%), Positives = 85/167 (50%), Gaps = 11/167 (6%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPP-VEAKRMLWSCTFCR-MKRSSGSQQC-- 588
N D C VC GG LLCC CP+VFH CH+P + W CTFCR + + C
Sbjct: 886 NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDN 945
Query: 589 --HHVSKTLERQMQPQDQLKCEFLLLKAYCHPQS-SFFTGIPFNIRDYGEPFQEAMWLDL 645
H + + P DQ KCE LLL YCH S F +P +I +Y + ++ M L
Sbjct: 946 LQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLST 1005
Query: 646 VKERL---ITEMYTVA-WFVRDMRLMFRNHKTFYKASDFGQVGLDLE 688
VK++L ++ Y + FV D+RL+F+N + F + QV D +
Sbjct: 1006 VKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQ 1052
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 82.0 bits (201), Expect = 2e-15
Identities = 63/207 (30%), Positives = 90/207 (43%), Gaps = 13/207 (6%)
Query: 505 EGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPP 564
E +G + + + R G G +N D C VC GG+LLCC CP+VFH CH+P
Sbjct: 941 EVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPA 1000
Query: 565 -VEAKRMLWSCTFCR-MKRSSGSQQCHHV-----SKTLERQMQPQDQLKCEFLLLKAYCH 617
+ W CT CR + + C + + DQ KCE L+L C+
Sbjct: 1001 LLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCN 1060
Query: 618 PQS-SFFTGIPFNIRDYGEPFQEAMWLDLVKERL----ITEMYTVAWFVRDMRLMFRNHK 672
S F + R Y + + M L +++ +L T V D+RLMF N
Sbjct: 1061 NLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCA 1120
Query: 673 TF-YKASDFGQVGLDLEAEFEKDLKDV 698
F Y S+ + G LE FE LK++
Sbjct: 1121 KFNYPDSEVAEAGRCLEVFFEGWLKEI 1147
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/143 (24%), Positives = 55/143 (38%), Gaps = 18/143 (12%)
Query: 139 LPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTND 198
LPPP PP P P P + + L+ S S P G + S D
Sbjct: 457 LPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPP----------GPACSQNMD 506
Query: 199 KLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHSPLGSMPEI-RDNSP 257
+ K EE +++ LL Q +L Q+ + PQ + + +G + I R +P
Sbjct: 507 IMHHKFELEEMQKDLELLL----QAQQPSL--QLSQTKSPQHLQQTIVGQINYIVRQPAP 560
Query: 258 -EPNDPEEPQEVSSTPSDKKGKK 279
+ EE + + P +G K
Sbjct: 561 VQSQSQEETLQATDEPPASQGSK 583
Score = 30.4 bits (67), Expect = 6.0
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 26/152 (17%)
Query: 118 PILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPR-----VSEPGTSSQQSDEILS- 171
P+ L + S TPL++PP SP R +S G S+ E+ S
Sbjct: 587 PLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSST 646
Query: 172 ESPSPSDPVLPLPALIQEGRSTSVTN-----DKLTSKMNAEEDSEEMPSLLTSTVQVASD 226
P +P + + + G +V + K+ S + + + ++ MPSL TS +Q
Sbjct: 647 RLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQ-NQAMPSLTTSHLQTV-- 703
Query: 227 NLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPE 258
+ HS SMP + +SP+
Sbjct: 704 ------------PSLVHSTFQSMPNLISDSPQ 723
>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
Length = 545
Score = 75.9 bits (185), Expect = 1e-13
Identities = 53/183 (28%), Positives = 76/183 (41%), Gaps = 30/183 (16%)
Query: 424 RSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHG 483
++K KK + + I V +P G +GIL ++ + G
Sbjct: 159 KAKPPKKPESSAEQQRLPLGNGIQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESG 218
Query: 484 SSVKCIRNEDGTWLTPNEFEVEGKGRN----AKNWKRNIRCEGMT----------LGEL- 528
S KCI+ G + TP++FE G G+N + K +R +G LG+
Sbjct: 219 GSKKCIQ-VGGEFYTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQG 277
Query: 529 -------------LKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSC 574
L +KN DEC VC GG+L+CC CPR FH C PP+ E W C
Sbjct: 278 SVPAPLALPSDPQLHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRC 337
Query: 575 TFC 577
+ C
Sbjct: 338 SSC 340
Score = 30.8 bits (68), Expect = 4.6
Identities = 12/27 (44%), Positives = 13/27 (48%)
Query: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIP 563
C VC G +L C C FH CH P
Sbjct: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
Length = 835
Score = 65.5 bits (158), Expect = 2e-10
Identities = 45/174 (25%), Positives = 73/174 (41%), Gaps = 10/174 (5%)
Query: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCR----MKRSSGSQQCHHV 591
C VC + G L+ C C FH DCH+P + + WSC+ C +K GS
Sbjct: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGA 687
Query: 592 SKT-LERQMQPQDQLKCEFLLLKAYCH----PQSSFFTGIPFNIRDYGEPFQEAMWLDLV 646
T + ++ P +Q KCE +LL +CH P T F++ G + +
Sbjct: 688 DSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPGGTLDLTLIRARL 747
Query: 647 KERLITEMYTVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLG 700
+E+L + F +D+ MF+ + Q + L+ FE + + G
Sbjct: 748 QEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAFG 801
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 60.8 bits (146), Expect = 4e-09
Identities = 70/310 (22%), Positives = 124/310 (40%), Gaps = 27/310 (8%)
Query: 157 SEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSL 216
S +SS SD S S + +E + S+ + +E + S
Sbjct: 193 SSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSK 252
Query: 217 LTSTVQVASDNLIPQIRDKEDPQEMPHSP-----LGSMPEIRDNSPEPNDPEEPQEVSST 271
+++ + ++NL Q + P+E+P P + P D N E + +
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNP 312
Query: 272 PSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTV 331
P+ + ++R + + R+ K + SR + + +R + P
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP------------ 360
Query: 332 ETRAQKARTECARKSRSEEIIDG-TSEMNEGKRSQKTP--STPRRVTQG---AASPGHGI 385
R + R + R S E I G SE+NE K +Q++P R++T + SP
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 386 QEKLQVVD-KVTQRKDDSTWNSEVMMRVQ---KARTKCARKSRSKEKKKEKDICSSSKRR 441
+++ +V D K ++ D NSE + + K R K +S+SKEK K K+ S R
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 442 FQKNIHRRGK 451
+K + R K
Sbjct: 481 EEKRMRSRSK 490
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/328 (21%), Positives = 132/328 (40%), Gaps = 24/328 (7%)
Query: 157 SEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSL 216
S +SS + S+S S SD A ++ + + K S+ + +E + S
Sbjct: 194 SSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRK-NSRKHKKEKKKRKKSK 252
Query: 217 LTSTVQVASDNLIPQIRDKEDPQEMPHSP-----LGSMPEIRDNSPEPNDPEEPQEVSST 271
+++ + ++NL Q + P+E+P P + P D N E + +
Sbjct: 253 KSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNP 312
Query: 272 PSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTV 331
P+ + ++R + + R+ K + SR + + +R + P + +
Sbjct: 313 PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQ----- 367
Query: 332 ETRAQKARTECARKSRSEEIIDGT-SEMNEGKRSQKTPST--PRRVTQG---AASPGHGI 385
RAQ+ R S E I G SE+NE K +Q++P R++T + SP
Sbjct: 368 --RAQRMRV-----SSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 386 QEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQKN 445
+++ +V D + K+ + K + K KS+S+ K KEK + +N
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 446 IHRRGKPKSDTVDFHCSKLPVTCGEAKG 473
+R + +S D K ++KG
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKG 508
>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
Length = 348
Score = 58.2 bits (139), Expect = 3e-08
Identities = 25/50 (50%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 529 LKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFC 577
L +KN DEC VC GG+L+CC CPR FH C PP+ E W C+ C
Sbjct: 94 LCQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 143
Score = 30.8 bits (68), Expect = 4.6
Identities = 12/27 (44%), Positives = 13/27 (48%)
Query: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIP 563
C VC G +L C C FH CH P
Sbjct: 237 CGVCGDGTDVLRCTHCAAAFHWRCHFP 263
>gi|38016945 deformed epidermal autoregulatory factor 1 [Homo
sapiens]
Length = 565
Score = 56.2 bits (134), Expect = 1e-07
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
Query: 462 SKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCE 521
S+LPV C G LYK ++ G +CI+ + W +P EFE ++K+WKR+IR
Sbjct: 201 SELPVRCRNISGTLYKNRLGSGGRGRCIKQGEN-WYSPTEFEAMAGRASSKDWKRSIRYA 259
Query: 522 GMTL------GELLKRKNSDECEVCC 541
G L G L S C CC
Sbjct: 260 GRPLQCLIQDGILNPHAASCTCAACC 285
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 54.7 bits (130), Expect = 3e-07
Identities = 35/109 (32%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 473 GILYKKKMKHGSSVKCIRNE---DGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELL 529
G + K+ K SS + R E D + E K KR + + + G+
Sbjct: 279 GGISNKRKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGY 338
Query: 530 KRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVE-AKRMLWSCTFC 577
+ + D CEVC QGG+++ C TCPR +H C P +E A WSC C
Sbjct: 339 ETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHC 387
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCRMKRSSGSQQ 587
C VC GG+LLCC CP +H C PP+ E W C C G Q
Sbjct: 419 CRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQ 470
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 53.5 bits (127), Expect = 7e-07
Identities = 92/418 (22%), Positives = 163/418 (38%), Gaps = 54/418 (12%)
Query: 202 SKMNAEEDSEEMPSLLTSTV------------QVASDNLIPQIRDKEDPQEM--PHSPLG 247
S +A + E+M +LL +++ + S+ P+++ K+ P++ P P
Sbjct: 9 SPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKS 68
Query: 248 SMP---------EIRDNSPE-PNDPEEPQEVS----STPSD-KKGKKRKRCIWSTPKRRH 292
++ D+S E P EE +EV+ S SD GKK+K+ + +++
Sbjct: 69 KRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKS 128
Query: 293 KKKSLPGGTASSRHGIQKKLKR------------VDQVPQKKDDSTCNSTVETRAQKART 340
K K K+ K +D V ++D T + + +Q R
Sbjct: 129 KSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTN-YKAFSQFVRP 187
Query: 341 ECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD 400
A K+ + + R T + P + + GA S + VV+ + +
Sbjct: 188 LIAAKNPKIAVSKMMMVLGAKWREFST-NNPFKGSSGA-SVAAAAAAAVAVVESMVTATE 245
Query: 401 DSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFH 460
+ V + ++KA+TK + ++ K K +K+ K + P +
Sbjct: 246 VAPPPPPVEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKV----APLKIKLGGF 301
Query: 461 CSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRC 520
SK + E + + +S+ DG+ T K R K K+
Sbjct: 302 GSKRKRSSSEDDDLDVESDFDD-ASINSYSVSDGS--TSRSSRSRKKLRTTKKKKKGE-- 356
Query: 521 EGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVE-AKRMLWSCTFC 577
E +T + + + D CEVC QGG+++ C TCPR +H C P +E A WSC C
Sbjct: 357 EEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHC 414
Score = 52.0 bits (123), Expect = 2e-06
Identities = 64/274 (23%), Positives = 104/274 (37%), Gaps = 40/274 (14%)
Query: 331 VETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQ 390
VE +KA+T+ + + G+ + + K+ + P ++ G G G + K
Sbjct: 253 VEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLG----GFGSKRKRS 308
Query: 391 VVDK----VTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQKNI 446
+ V DD++ NS + +R+ +RK KKK+K ++ +
Sbjct: 309 SSEDDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKG---------EEEV 359
Query: 447 HRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCI-----RNEDGTWLTPNE 501
++D D+ C C + I+ + C+ + +G W P+
Sbjct: 360 TAVDGYETDHQDY-CE----VCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPH- 413
Query: 502 FEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDE-------CEVCCQGGQLLCCGTCPR 554
E EG AK EG + E + +E C VC GG+LLCC TCP
Sbjct: 414 CEKEGIQWEAKE----DNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPS 469
Query: 555 VFHEDCHIPPV-EAKRMLWSCTFCRMKRSSGSQQ 587
+H C PP+ E W C C G Q
Sbjct: 470 SYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQ 503
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 53.1 bits (126), Expect = 9e-07
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 23/128 (17%)
Query: 451 KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRN 510
+P+++ D + G G + KK+K G + + G E EV+G
Sbjct: 318 EPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDG---- 373
Query: 511 AKNWKRNIRCEGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVE-AKR 569
+ + D CEVC QGG+++ C TCPR +H C P ++ A
Sbjct: 374 ------------------YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPE 415
Query: 570 MLWSCTFC 577
WSC C
Sbjct: 416 GKWSCPHC 423
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 490 RNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDE-CEVCCQGGQLLC 548
R +G W P+ E EG AK + EG GE + + E C VC GG+LLC
Sbjct: 412 RAPEGKWSCPH-CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLC 470
Query: 549 CGTCPRVFHEDCHIPPV-EAKRMLWSCTFC 577
C C +H C PP+ + W C C
Sbjct: 471 CDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/209 (25%), Positives = 78/209 (37%), Gaps = 27/209 (12%)
Query: 141 PPQPPQPSC-SPCAPRVSEPGTSSQQSDEI-LSESPSPSDPVLPLPALIQEGRSTSVTND 198
P P PS S + R S P +S + E + SP S P P P+ EG T + +
Sbjct: 1515 PELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKE 1574
Query: 199 KLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPE 258
+ E+ EE P ++ I + + E P LG E R E
Sbjct: 1575 E-------AENQEEKPE---------KNSRIGEKMETEADAPSPAPSLGERLEPRKIPLE 1618
Query: 259 PNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSR-HGIQKKLKRVDQ 317
P P E+ P +G + K STP R ++K L G R G L + +
Sbjct: 1619 DEVPGVPGEMEPEPG-YRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRED 1677
Query: 318 V-------PQKKDDSTCNSTVETRAQKAR 339
V P +D+ N E + +K R
Sbjct: 1678 VKGDRELRPGPRDEPRSNGRREEKTEKPR 1706
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 53.1 bits (126), Expect = 9e-07
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 23/128 (17%)
Query: 451 KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRN 510
+P+++ D + G G + KK+K G + + G E EV+G
Sbjct: 318 EPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDG---- 373
Query: 511 AKNWKRNIRCEGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVE-AKR 569
+ + D CEVC QGG+++ C TCPR +H C P ++ A
Sbjct: 374 ------------------YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPE 415
Query: 570 MLWSCTFC 577
WSC C
Sbjct: 416 GKWSCPHC 423
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 490 RNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDE-CEVCCQGGQLLC 548
R +G W P+ E EG AK + EG GE + + E C VC GG+LLC
Sbjct: 412 RAPEGKWSCPH-CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLC 470
Query: 549 CGTCPRVFHEDCHIPPV-EAKRMLWSCTFC 577
C C +H C PP+ + W C C
Sbjct: 471 CDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
Score = 33.1 bits (74), Expect = 0.92
Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 141 PPQPPQPSC-SPCAPRVSEPGTSSQQSDEI-LSESPSPSDPVLPLPALIQEGRSTSVTND 198
P P PS S + R S P +S + E + SP S P P P+ EG T + +
Sbjct: 1515 PELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKE 1574
Query: 199 KLTSKMNAEEDSEEMPSLLTSTVQVASD--NLIPQIRDKEDPQEMP-HSPLGSMPEIRDN 255
+ + +E+ E S + ++ +D + P + ++ +P+++P + +P +
Sbjct: 1575 EAEN----QEEKPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVP--GEM 1628
Query: 256 SPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLP 298
PEP + ++ D++ + R + RR +K P
Sbjct: 1629 EPEPGYRGDREKSEDVKGDRELRPGPRDEPRSNGRREEKTEKP 1671
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 53.1 bits (126), Expect = 9e-07
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 23/128 (17%)
Query: 451 KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRN 510
+P+++ D + G G + KK+K G + + G E EV+G
Sbjct: 377 EPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDG---- 432
Query: 511 AKNWKRNIRCEGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVE-AKR 569
+ + D CEVC QGG+++ C TCPR +H C P ++ A
Sbjct: 433 ------------------YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPE 474
Query: 570 MLWSCTFC 577
WSC C
Sbjct: 475 GKWSCPHC 482
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 490 RNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRKNSDE-CEVCCQGGQLLC 548
R +G W P+ E EG AK + EG GE + + E C VC GG+LLC
Sbjct: 471 RAPEGKWSCPH-CEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLC 529
Query: 549 CGTCPRVFHEDCHIPPV-EAKRMLWSCTFC 577
C C +H C PP+ + W C C
Sbjct: 530 CDACISSYHIHCLNPPLPDIPNGEWLCPRC 559
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/209 (25%), Positives = 78/209 (37%), Gaps = 27/209 (12%)
Query: 141 PPQPPQPSC-SPCAPRVSEPGTSSQQSDEI-LSESPSPSDPVLPLPALIQEGRSTSVTND 198
P P PS S + R S P +S + E + SP S P P P+ EG T + +
Sbjct: 1574 PELMPDPSADSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKE 1633
Query: 199 KLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPE 258
+ E+ EE P ++ I + + E P LG E R E
Sbjct: 1634 E-------AENQEEKPE---------KNSRIGEKMETEADAPSPAPSLGERLEPRKIPLE 1677
Query: 259 PNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKRRHKKKSLPGGTASSR-HGIQKKLKRVDQ 317
P P E+ P +G + K STP R ++K L G R G L + +
Sbjct: 1678 DEVPGVPGEMEPEPG-YRGDREKSATESTPGERGEEKPLDGQEHRERPEGETGDLGKRED 1736
Query: 318 V-------PQKKDDSTCNSTVETRAQKAR 339
V P +D+ N E + +K R
Sbjct: 1737 VKGDRELRPGPRDEPRSNGRREEKTEKPR 1765
>gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]
Length = 1004
Score = 52.8 bits (125), Expect = 1e-06
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRM---LWSCTFCRMKRSSGSQQ 587
N D C+ C +GG LLCC CP FH C PP+ + + W C C ++R Q+
Sbjct: 55 NHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQK 112
Score = 36.6 bits (83), Expect = 0.083
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 505 EGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPP 564
E G+N K + + G+ L K C C+ L+ C CP +FH DC PP
Sbjct: 248 ETTGKNVKKTQHELDHNGLVP---LPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPP 304
Query: 565 VEAKRM-LWSC 574
+ A + W C
Sbjct: 305 LTAMPLGRWMC 315
>gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]
Length = 704
Score = 52.8 bits (125), Expect = 1e-06
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRM---LWSCTFCRMKRSSGSQQ 587
N D C+ C +GG LLCC CP FH C PP+ + + W C C ++R Q+
Sbjct: 55 NHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQK 112
Score = 36.6 bits (83), Expect = 0.083
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 505 EGKGRNAKNWKRNIRCEGMTLGELLKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPP 564
E G+N K + + G+ L K C C+ L+ C CP +FH DC PP
Sbjct: 248 ETTGKNVKKTQHELDHNGLVP---LPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPP 304
Query: 565 VEAKRM-LWSC 574
+ A + W C
Sbjct: 305 LTAMPLGRWMC 315
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 50.4 bits (119), Expect = 6e-06
Identities = 69/324 (21%), Positives = 119/324 (36%), Gaps = 47/324 (14%)
Query: 123 APTGLAEGSSLHTPLALPPPQP------------PQPSCSPCAPRVSEPGTSSQQSDEIL 170
A GL G L LP P P P+ P + PG + L
Sbjct: 130 AVAGLLPGGGL-----LPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGAN-------L 177
Query: 171 SESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIP 230
+ +D +L L + + + + V ++ + ++ S+E+ + V+ A +
Sbjct: 178 NSQSLAADQLLKLMSTV-DPKLNHVAAGLVSPSLKSDTSSKEIEEAM-KRVREAQSLISA 235
Query: 231 QIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWSTPKR 290
I + ++ HS S R +P + + S S K + R+R +P+R
Sbjct: 236 AIEPDKKEEKRRHSRSRSRSR-RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRS--KSPRR 292
Query: 291 RHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEE 350
R G + S + K K + + K ST +R R+SRS
Sbjct: 293 RRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRS-- 350
Query: 351 IIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMM 410
G RS K P +P+R + SP +EK + DK R + S
Sbjct: 351 ----------GTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS---- 396
Query: 411 RVQKARTKCARKSRSKEKKKEKDI 434
+K ++K K R ++ + +KD+
Sbjct: 397 --KKKKSKDKEKDRERKSESDKDV 418
>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
Length = 634
Score = 49.7 bits (117), Expect = 9e-06
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEA-KRMLWSCTFCR 578
+ D C VC + GQLL C TC RV+H DC PP++ + +W C C+
Sbjct: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
Length = 680
Score = 49.7 bits (117), Expect = 9e-06
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 533 NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEA-KRMLWSCTFCR 578
+ D C VC + GQLL C TC RV+H DC PP++ + +W C C+
Sbjct: 487 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 533
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 535 DECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCRMKRSSGSQQC 588
D C VC + G LLCC TC V+H +C PP+ E W C C + G C
Sbjct: 391 DHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDC 445
Score = 32.7 bits (73), Expect = 1.2
Identities = 51/263 (19%), Positives = 92/263 (34%), Gaps = 55/263 (20%)
Query: 107 GASYERQSRDTPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQS 166
G +RQS+ +P + +H LPP Q + P+ ++P Q
Sbjct: 2360 GTGEQRQSKLSPQM-----------QVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQ 2408
Query: 167 DEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASD 226
++ SP+ P + +Q T T +++ SE P+ S+ +
Sbjct: 2409 ----TQPQSPAQPEVQTQPEVQ----TQTT-------VSSHVPSEAQPTHAQSSKPQVAA 2453
Query: 227 NLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPSDKKGKKRKRCIWS 286
PQ + SP S IR ++P P + +V +T S
Sbjct: 2454 QSQPQSNVQGQSPVRVQSP--SQTRIRPSTPSQLSPGQQSQVQTTTSQ-----------P 2500
Query: 287 TPKRRHKKKSLP--GGTASSRHGIQKKLKRVDQVPQKKDDS-----------TCNSTVE- 332
P + H +P G S + K ++ + QKK + CN ++
Sbjct: 2501 IPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKY 2560
Query: 333 --TRAQKARTECARKSRSEEIID 353
+ K + A+K + EE ++
Sbjct: 2561 ILDKIDKEEKQAAKKRKREESVE 2583
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 48.9 bits (115), Expect = 2e-05
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 535 DECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSCTFCRMKRSSGSQQC 588
D C VC + G LLCC TC V+H +C PP+ E W C C + G C
Sbjct: 391 DHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDC 445
Score = 35.4 bits (80), Expect = 0.18
Identities = 66/342 (19%), Positives = 113/342 (33%), Gaps = 52/342 (15%)
Query: 107 GASYERQSRDTPIL-------LEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEP 159
G +RQS+ +P + L + G + P P PQP P +P E
Sbjct: 2234 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEV 2293
Query: 160 GTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTNDKLTSKMNAEEDSEEMPSLLTS 219
T + + S PS+ P Q + + S + + T
Sbjct: 2294 QTQPEVQTQTTVSSHVPSE---AQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTR 2350
Query: 220 TVQVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPE-EPQEVSSTPSDKKGK 278
L P + Q P+ P P P+ +PQ SST + G+
Sbjct: 2351 IRPSTPSQLSP--GQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQ 2408
Query: 279 KRKRCIWSTPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKA 338
+ S+P R + IQ+ +V VPQ + S +++
Sbjct: 2409 TLNQVTVSSPSRPQLQ-------------IQQPQPQVIAVPQLQQQVQVLSQIQS----- 2450
Query: 339 RTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQR 398
+++ G Q P ++ Q +A H IQ + V Q
Sbjct: 2451 -----------QVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQ- 2498
Query: 399 KDDSTWNSEVMMRVQKARTKCARKSRSK-EKKKEKDICSSSK 439
E + RVQ+ R + +K + + E K+E + +S++
Sbjct: 2499 --------EQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQ 2532
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,715,712
Number of Sequences: 37866
Number of extensions: 1635911
Number of successful extensions: 14302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 670
Number of HSP's that attempted gapping in prelim test: 11356
Number of HSP's gapped (non-prelim): 2953
length of query: 713
length of database: 18,247,518
effective HSP length: 109
effective length of query: 604
effective length of database: 14,120,124
effective search space: 8528554896
effective search space used: 8528554896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.