Guide to the Human Genome
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Search of human proteins with 188595697

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]               642   0.0  
gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens]                642   0.0  
gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo...   254   6e-68
gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo...   254   6e-68
gi|5032115 sprouty 2 [Homo sapiens]                                   241   7e-64
gi|27501452 sprouty homolog 3 [Homo sapiens]                          229   3e-60
gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform...    59   7e-09
gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform...    59   7e-09
gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sa...    57   3e-08
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a...    55   1e-07
gi|93102379 low density lipoprotein-related protein 1B precursor...    38   0.012
gi|154759249 keratin associated protein 10-11 [Homo sapiens]           37   0.016
gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]         37   0.028
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ...    36   0.047
gi|126012562 low density lipoprotein-related protein 1 [Homo sap...    34   0.14 
gi|55770876 notch4 preproprotein [Homo sapiens]                        34   0.18 
gi|60279697 keratin associated protein 5-7 [Homo sapiens]              33   0.23 
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          33   0.31 
gi|150170722 G protein-coupled receptor 50 [Homo sapiens]              33   0.31 
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr...    33   0.40 
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...    33   0.40 
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]         33   0.40 
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        33   0.40 
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        33   0.40 
gi|31543806 thrombospondin 4 precursor [Homo sapiens]                  32   0.52 
gi|158534055 round spermatid basic protein 1-like [Homo sapiens]       32   0.52 
gi|60593036 keratin associated protein 5-3 [Homo sapiens]              32   0.52 
gi|60593038 keratin associated protein 5-4 [Homo sapiens]              32   0.52 
gi|134244285 Notch homolog 3 [Homo sapiens]                            32   0.68 
gi|61743980 stabilin 2 precursor [Homo sapiens]                        32   0.68 

>gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]
          Length = 299

 Score =  642 bits (1657), Expect = 0.0
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL 60
           MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL
Sbjct: 1   MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL 60

Query: 61  TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV 120
           TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV
Sbjct: 61  TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV 120

Query: 121 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW 180
           ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW
Sbjct: 121 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW 180

Query: 181 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA 240
           VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA
Sbjct: 181 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA 240

Query: 241 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF 299
           LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF
Sbjct: 241 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF 299


>gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens]
          Length = 322

 Score =  642 bits (1657), Expect = 0.0
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL 60
           MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL
Sbjct: 24  MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL 83

Query: 61  TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV 120
           TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV
Sbjct: 84  TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV 143

Query: 121 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW 180
           ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW
Sbjct: 144 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW 203

Query: 181 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA 240
           VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA
Sbjct: 204 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA 263

Query: 241 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF 299
           LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF
Sbjct: 264 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF 322


>gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo
           sapiens]
          Length = 319

 Score =  254 bits (649), Expect = 6e-68
 Identities = 135/298 (45%), Positives = 186/298 (62%), Gaps = 29/298 (9%)

Query: 16  VMVQPLLDSR--MSHSRLQHPLTILPIDQVKTSHVENDYIDNPSL----ALTTGPKRTRG 69
           V+ QP LDSR  + + R   P  IL +DQ+K     N+Y + PS+    A  T P++ + 
Sbjct: 15  VIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKH 74

Query: 70  GAP-ELAPTPARCDQDVTH-----HWI-------------SFSGRPSSVSSSSSTSSDQR 110
               E+ P     + +  H     H +             + +G  +S  S+SS SS+Q 
Sbjct: 75  ERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQG 134

Query: 111 LLDHMAPP-PVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKE 169
           LL    P  PV    S RA+R QPK +     DLKG ++  +L +H  +CE CGKCKC E
Sbjct: 135 LLGRSPPTRPVPGHRSERAIRTQPKQLIVD--DLKG-SLKEDLTQHKFICEQCGKCKCGE 191

Query: 170 CASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRS 229
           C +PRTLPSC  CN++CLCSA+++V YGTCMCLV+GIFYHC+N+D+  S +D+PCSCS+S
Sbjct: 192 CTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQS 251

Query: 230 NCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAAS 287
           +CC+R+  MGA+S+ LPCLLCY PA GC+KL +R YD + RPGCRCK++N+V CK  S
Sbjct: 252 HCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRCKNSNTVYCKLES 309


>gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo
           sapiens]
          Length = 319

 Score =  254 bits (649), Expect = 6e-68
 Identities = 135/298 (45%), Positives = 186/298 (62%), Gaps = 29/298 (9%)

Query: 16  VMVQPLLDSR--MSHSRLQHPLTILPIDQVKTSHVENDYIDNPSL----ALTTGPKRTRG 69
           V+ QP LDSR  + + R   P  IL +DQ+K     N+Y + PS+    A  T P++ + 
Sbjct: 15  VIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKH 74

Query: 70  GAP-ELAPTPARCDQDVTH-----HWI-------------SFSGRPSSVSSSSSTSSDQR 110
               E+ P     + +  H     H +             + +G  +S  S+SS SS+Q 
Sbjct: 75  ERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQG 134

Query: 111 LLDHMAPP-PVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKE 169
           LL    P  PV    S RA+R QPK +     DLKG ++  +L +H  +CE CGKCKC E
Sbjct: 135 LLGRSPPTRPVPGHRSERAIRTQPKQLIVD--DLKG-SLKEDLTQHKFICEQCGKCKCGE 191

Query: 170 CASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRS 229
           C +PRTLPSC  CN++CLCSA+++V YGTCMCLV+GIFYHC+N+D+  S +D+PCSCS+S
Sbjct: 192 CTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQS 251

Query: 230 NCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAAS 287
           +CC+R+  MGA+S+ LPCLLCY PA GC+KL +R YD + RPGCRCK++N+V CK  S
Sbjct: 252 HCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRCKNSNTVYCKLES 309


>gi|5032115 sprouty 2 [Homo sapiens]
          Length = 315

 Score =  241 bits (614), Expect = 7e-64
 Identities = 125/276 (45%), Positives = 169/276 (61%), Gaps = 29/276 (10%)

Query: 31  LQHPLTILPIDQVKTSHVENDYIDNPSLALTTGPK-----------RTRGGAPELAPTP- 78
           L   + +L +DQ++     N+Y + P++    G K               G PE    P 
Sbjct: 34  LTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPR 93

Query: 79  ---------ARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLL-DHMAPPPVADQASPRA 128
                    AR     +   +S   R S+ +S+SS+SS+QRLL    +  PVAD      
Sbjct: 94  LQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGI---- 149

Query: 129 VRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLC 188
           +R+QPK    +P +LK P    +L  H   CE CGKCKCKEC  PR LPS W+C+++CLC
Sbjct: 150 IRVQPKS-ELKPGELK-PLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLC 207

Query: 189 SAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLPCL 248
           SAQ +++YGTC+C V+G+FYHC+N DDE +CAD+PCSCS+S+CC RWS MG +S+ LPCL
Sbjct: 208 SAQNVIDYGTCVCCVKGLFYHCSN-DDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCL 266

Query: 249 LCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICK 284
            CYLPA GC+KL Q  YDR+ RPGCRCK++N+V CK
Sbjct: 267 WCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCK 302


>gi|27501452 sprouty homolog 3 [Homo sapiens]
          Length = 288

 Score =  229 bits (583), Expect = 3e-60
 Identities = 124/285 (43%), Positives = 163/285 (57%), Gaps = 49/285 (17%)

Query: 37  ILPIDQVKTSHVENDYIDNP----------------------SLA-LTTGPKRTRGGAPE 73
           ILPI+Q++++H  NDY++ P                      SLA + T   R+     +
Sbjct: 12  ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQ 71

Query: 74  LAPTPARCDQDVTHHWISFSGRPSSVSSS---SSTSSDQRLLDHMAPPPVADQASPRAVR 130
           L P P    Q             SS++SS   S+T+SDQRLL  + P P    +    +R
Sbjct: 72  LQPLPQHLSQ-------------SSIASSMSHSTTASDQRLLASITPSP----SGQSIIR 114

Query: 131 IQPKVVHCQPLD--LKGPAVPP--ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQEC 186
            QP        D  LKG A        +H  +CE CG+CKC  C + R LPSCW+CNQ C
Sbjct: 115 TQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRC 174

Query: 187 LCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLP 246
           LCSA++L++YGTC+C V+G+FYHC+  DDE +CAD PCSC  S+C  RW+ M  +S+ LP
Sbjct: 175 LCSAESLLDYGTCLCCVKGLFYHCST-DDEDNCADEPCSCGPSSCFVRWAAMSLISLFLP 233

Query: 247 CLLCYLPATGCVKLAQRGYDRLRRPGCRCK-HTNSVICKAASGDA 290
           CL CYLP  GC+ L Q+GYD LRRPGCRCK HTN+V  K +SG A
Sbjct: 234 CLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSA 278


>gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform b
           [Homo sapiens]
          Length = 415

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%)

Query: 184 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 241
           Q+   S +T +   +CM     + YHC + D EG   D PCSC  S+   C RW  + AL
Sbjct: 324 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 381

Query: 242 SVVLPCLLCYLPATGC 257
           S + PC+ CYLP   C
Sbjct: 382 SFLAPCMCCYLPLRAC 397


>gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform a
           [Homo sapiens]
          Length = 418

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%)

Query: 184 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 241
           Q+   S +T +   +CM     + YHC + D EG   D PCSC  S+   C RW  + AL
Sbjct: 327 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 384

Query: 242 SVVLPCLLCYLPATGC 257
           S + PC+ CYLP   C
Sbjct: 385 SFLAPCMCCYLPLRAC 400


>gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo
           sapiens]
          Length = 444

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%)

Query: 198 TCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGALSVVLPCLLCYLPAT 255
           +CM   + + YHC + D EG  +D PCSC  S+   C RW  + ALS ++PC+ CY+P  
Sbjct: 367 SCMLCAESMLYHCMS-DSEGDFSD-PCSCDTSDDKFCLRWLALVALSFIVPCMCCYVPLR 424

Query: 256 GC 257
            C
Sbjct: 425 MC 426


>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
           [Homo sapiens]
          Length = 410

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 4/73 (5%)

Query: 193 LVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNC--CARWSFMGALSVVLPCLLC 250
           LV   +C+   + + YHC + D EG  +D PC+C   +    ARW+ + ALS+ +PCL C
Sbjct: 325 LVRRLSCLWCAESLLYHCLS-DAEGDFSD-PCACEPGHPRPAARWAALAALSLAVPCLCC 382

Query: 251 YLPATGCVKLAQR 263
           Y P   C  +A R
Sbjct: 383 YAPLRACHWVAAR 395


>gi|93102379 low density lipoprotein-related protein 1B precursor
            [Homo sapiens]
          Length = 4599

 Score = 37.7 bits (86), Expect = 0.012
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 23/85 (27%)

Query: 170  CASPRTLPSCWVCNQECLCSAQT----LVNYGTCMCLVQGIF---------YHCTNEDDE 216
            C + R +P  W+C++E  C  QT       + TC  L Q +          +HC ++DD 
Sbjct: 934  CGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDC 993

Query: 217  G----------SCADHPCSCSRSNC 231
            G          SC D+   CS   C
Sbjct: 994  GDGSDEVGCVHSCFDNQFRCSSGRC 1018



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 169 ECASPRTLPSCWVCN--QEC---------LCSAQTL----VNYGTCMCLVQGIFYHCTNE 213
           +C + R +P  W+C+   +C          C+A+T      + G   C+ +   + C  E
Sbjct: 892 KCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRA--WLCDRE 949

Query: 214 DDEGSCADHPCSCSRSNC 231
           DD G   D   SC    C
Sbjct: 950 DDCGDQTDEMASCEFPTC 967


>gi|154759249 keratin associated protein 10-11 [Homo sapiens]
          Length = 298

 Score = 37.4 bits (85), Expect = 0.016
 Identities = 54/237 (22%), Positives = 80/237 (33%), Gaps = 53/237 (22%)

Query: 74  LAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASPR----AV 129
           L  TP  C   V+      +  PS+  S  ++S         +  P    +SP      V
Sbjct: 45  LVCTPVSC---VSSPCCQAACEPSACQSGCTSSCTPSCCQQSSCQPACCTSSPCQQACCV 101

Query: 130 RIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKE-------CASPRTLPSCWV- 181
            +  K V C+P+      VP       + C A   C C++       CAS    P+C V 
Sbjct: 102 PVCCKTVCCKPVC----CVP-------VCCGAASSC-CRQSSCQPACCASSSCQPACCVP 149

Query: 182 --CNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMG 239
             C   C  S        TC            +ED    C    C  +   CC   S+  
Sbjct: 150 VCCKPVCCVS--------TC------------SEDSSSCCQQSSCQPA---CCTSSSYQQ 186

Query: 240 ALSVVLPCLLCYLPATGCVKLAQR-GYDRLRRPGCRCKHTNSVICKAASGDAKTSRP 295
           A  V + C   Y     CV +  R    R ++P C+     +  C+ +S  +    P
Sbjct: 187 ACCVPVCCKTVYCKPICCVPVCSRASSSRCQQPSCQPACCTTSCCRPSSSVSLLCHP 243


>gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]
          Length = 474

 Score = 36.6 bits (83), Expect = 0.028
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 10/109 (9%)

Query: 38  LPIDQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWIS-FSGRP 96
           LP+++    HV +    NP ++   G KR    + E +P   +    VT   +S FS   
Sbjct: 26  LPVEE----HVGSQTFVNPHVSSFQGSKRGLNSSFETSPKKVKWSSTVTSPRLSLFSDGD 81

Query: 97  SSVSSSSSTSSDQRLLDHMAPP-----PVADQASPRAVRIQPKVVHCQP 140
           SS S  + +SS++       PP     P   + SP+  R  P+   C P
Sbjct: 82  SSESEDTLSSSERSKGSGSRPPTPKSSPQKTRKSPQVTRGSPQKTSCSP 130


>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
           [Homo sapiens]
          Length = 494

 Score = 35.8 bits (81), Expect = 0.047
 Identities = 29/100 (29%), Positives = 38/100 (38%), Gaps = 26/100 (26%)

Query: 162 CGKCKCKE------CASPRTL-----PSCWVC--NQECLCSAQTLVNYGTCMC------- 201
           CGKCKC +      C  P         S  +C  +Q+ +CS     + G C C       
Sbjct: 112 CGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSG 171

Query: 202 LVQGIF-----YHCTNEDDEGSCADH-PCSCSRSNCCARW 235
           LV G F       C +++ E  C  H  C C    C A W
Sbjct: 172 LVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGW 211


>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
          Length = 4544

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 18/80 (22%)

Query: 170  CASPRTLPSCWVCNQECLCSAQT----LVNYGTCMCLVQ---------GIFYHCTNEDDE 216
            CAS R +P  W C+ +  C  ++       Y TC  L Q          I + C N++D 
Sbjct: 943  CASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDC 1002

Query: 217  GSCAD-----HPCSCSRSNC 231
            G  +D     H CS ++  C
Sbjct: 1003 GDNSDEAGCSHSCSSTQFKC 1022



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 17/78 (21%)

Query: 169 ECASPRTLPSCWVCN-----------QECLCSAQTL-VNYGTC---MCLVQGIFYHCTNE 213
           +C + R +P+ W+C+               CSA+T   N  +C    C+   I + C  +
Sbjct: 901 KCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCI--PISWTCDLD 958

Query: 214 DDEGSCADHPCSCSRSNC 231
           DD G  +D   SC+   C
Sbjct: 959 DDCGDRSDESASCAYPTC 976



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 22/90 (24%), Positives = 30/90 (33%), Gaps = 32/90 (35%)

Query: 160  EACGKCKCK----ECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDD 215
            E C +  C+     C + R +P  W C+ +                        C +  D
Sbjct: 3529 EECDERTCEPYQFRCKNNRCVPGRWQCDYD----------------------NDCGDNSD 3566

Query: 216  EGSCADHPC-----SCSRSNCCA-RWSFMG 239
            E SC   PC     SC+   C A RW   G
Sbjct: 3567 EESCTPRPCSESEFSCANGRCIAGRWKCDG 3596


>gi|55770876 notch4 preproprotein [Homo sapiens]
          Length = 2003

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 26/87 (29%), Positives = 30/87 (34%), Gaps = 15/87 (17%)

Query: 159 CEACGKCKCKECASPRTLPSC---WV---CNQECLCSAQTLVNYGTCMCLVQGIFYHC-- 210
           C   G+C  +  AS R   SC   W    C     CSA   VN G C+     I  HC  
Sbjct: 127 CSKRGRCHIQ--ASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPP 184

Query: 211 -----TNEDDEGSCADHPCSCSRSNCC 232
                  E D   C   P  C +   C
Sbjct: 185 GFEGHACERDVNECFQDPGPCPKGTSC 211


>gi|60279697 keratin associated protein 5-7 [Homo sapiens]
          Length = 165

 Score = 33.5 bits (75), Expect = 0.23
 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 7/74 (9%)

Query: 162 CGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCAD 221
           CG C C +C+  +  P C  C+  C  S         C C        C +     SC  
Sbjct: 87  CGSCGCSQCSCYK--PCC--CSSGCGSSCCQSSCCKPCCCQSSCCKPCCCSSGCGSSCCQ 142

Query: 222 HPC---SCSRSNCC 232
             C    CS+S+CC
Sbjct: 143 SSCCNPCCSQSSCC 156



 Score = 28.1 bits (61), Expect = 9.8
 Identities = 23/85 (27%), Positives = 31/85 (36%), Gaps = 11/85 (12%)

Query: 159 CEACGKCKCKECASPRTLPSCWV-----CNQECLCSA-----QTLVNYGTCMCLVQGIFY 208
           C  CG   C  C S   +P C       C   C CS+      +    G+C     G   
Sbjct: 21  CGGCGS-GCGGCGSSCCVPVCCCKPVCCCVPACSCSSCGSCGGSKGGCGSCGGSKGGCGS 79

Query: 209 HCTNEDDEGSCADHPCSCSRSNCCA 233
              ++   GSC    CSC +  CC+
Sbjct: 80  CGGSKGGCGSCGCSQCSCYKPCCCS 104


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 39/161 (24%), Positives = 63/161 (39%), Gaps = 25/161 (15%)

Query: 4   PIPQSAPLTPNSVMV-------QPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNP 56
           P P ++P+ P++          +P L+S    S     + + P     TS V+ +  +  
Sbjct: 532 PTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKF 591

Query: 57  SLALTTGPKRTRGGAPELAPTPARCDQDVT---HHWISFSGRPSSVSSSSS--------- 104
           + A T+ P  +   AP ++P  +      +    H    S  PSSV   SS         
Sbjct: 592 TAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRS 651

Query: 105 ---TSSDQRLLDHMAP---PPVADQASPRAVRIQPKVVHCQ 139
              +SS    +   +P   PP A   SP+A  +QP V   Q
Sbjct: 652 AQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQ 692


>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
          Length = 617

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 35/141 (24%), Positives = 49/141 (34%), Gaps = 10/141 (7%)

Query: 6   PQSAPLTPNSVMVQPLLDSRMS---HSR------LQHPLTILPIDQVKTSHVENDYIDNP 56
           P S    P S   +P+    +S   HS+        HP       +  TSH E    D P
Sbjct: 462 PDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYP 521

Query: 57  SLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMA 116
             A T+ PK T    PEL+ +       + H     S  P S +SS +    +     + 
Sbjct: 522 KPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPES-ASSPAAGPTKPAASQLE 580

Query: 117 PPPVADQASPRAVRIQPKVVH 137
              +AD   P  V       H
Sbjct: 581 SDTIADLPDPTVVTTSTNDYH 601


>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding
           protein [Homo sapiens]
          Length = 1403

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%)

Query: 155 HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 208
           H+ LC       C   ++P    S   C + C+C A       T V  G C CL  G +Y
Sbjct: 744 HYELCGDSCPVSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 801

Query: 209 HCTNEDDEGSCADHPCSC 226
                   G   +  C C
Sbjct: 802 PLGEVFYPGPECERRCEC 819


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%)

Query: 155  HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 208
            H+ LC       C   ++P    S   C + C+C A       T V  G C CL  G +Y
Sbjct: 2344 HYELCGDSCPVSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 2401

Query: 209  HCTNEDDEGSCADHPCSC 226
                    G   +  C C
Sbjct: 2402 PLGEVFYPGPECERRCEC 2419


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%)

Query: 155  HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 208
            H+ LC       C   ++P    S   C + C+C A       T V  G C CL  G +Y
Sbjct: 4744 HYELCGDSCPVSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 4801

Query: 209  HCTNEDDEGSCADHPCSC 226
                    G   +  C C
Sbjct: 4802 PLGEVFYPGPECERRCEC 4819



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 21/78 (26%), Positives = 27/78 (34%), Gaps = 8/78 (10%)

Query: 155  HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 208
            H+ LC       C   ++P    S   C + C+C A       T V  G C CL    +Y
Sbjct: 2342 HYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY 2399

Query: 209  HCTNEDDEGSCADHPCSC 226
                    G   D  C C
Sbjct: 2400 PLGQTFYPGPGCDSLCRC 2417



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 21/78 (26%), Positives = 27/78 (34%), Gaps = 8/78 (10%)

Query: 155  HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 208
            H+ LC       C   ++P    S   C + C+C A       T V  G C CL    +Y
Sbjct: 3543 HYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY 3600

Query: 209  HCTNEDDEGSCADHPCSC 226
                    G   D  C C
Sbjct: 3601 PLGQTFYPGPGCDSLCRC 3618


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 14/78 (17%)

Query: 165  CKCK-ECASPRTLPSCW-VCNQECLCSAQTL------VNYGTCMCLVQGIFYHCTNEDDE 216
            C C   C SPR  PSC  +C + C+C+   L      +   +C C     +Y    E   
Sbjct: 1053 CACPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFS 1110

Query: 217  GSCADHPCSC---SRSNC 231
             +C +H C C   SR  C
Sbjct: 1111 PNCTEH-CRCWPGSRVEC 1127



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/72 (29%), Positives = 26/72 (36%), Gaps = 9/72 (12%)

Query: 167  CKECASPRTLPSCWVCNQECLC------SAQTLVNYGTCMCLVQGIFYHCTNED--DEGS 218
            C    +PR  P    C + C C      S  + V  G C C      YH   E    E +
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 219  CADHPCSCSRSN 230
            C    C+CS  N
Sbjct: 1889 CT-RLCTCSVHN 1899


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 14/78 (17%)

Query: 165  CKCK-ECASPRTLPSCW-VCNQECLCSAQTL------VNYGTCMCLVQGIFYHCTNEDDE 216
            C C   C SPR  PSC  +C + C+C+   L      +   +C C     +Y    E   
Sbjct: 1053 CACPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFS 1110

Query: 217  GSCADHPCSC---SRSNC 231
             +C +H C C   SR  C
Sbjct: 1111 PNCTEH-CRCWPGSRVEC 1127



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 21/72 (29%), Positives = 26/72 (36%), Gaps = 9/72 (12%)

Query: 167  CKECASPRTLPSCWVCNQECLC------SAQTLVNYGTCMCLVQGIFYHCTNED--DEGS 218
            C    +PR  P    C + C C      S  + V  G C C      YH   E    E +
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 219  CADHPCSCSRSN 230
            C    C+CS  N
Sbjct: 1889 CT-RLCTCSVHN 1899


>gi|31543806 thrombospondin 4 precursor [Homo sapiens]
          Length = 961

 Score = 32.3 bits (72), Expect = 0.52
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 20/102 (19%)

Query: 145 GPAVPPELDKHFLLCEACGKCK----------CK---ECASPRTLPSCWVCNQECLCSAQ 191
           G  VP  +  + L    CG CK          CK    C +P   P C V N +C+   Q
Sbjct: 386 GACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNP-CSV-NAQCIEERQ 443

Query: 192 TLVNYGTCMCLV--QGIFYHCTNEDDEGSCADHPCSCSRSNC 231
             V   TC+C V   G  Y C  + D  S  D    CS  NC
Sbjct: 444 GDV---TCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNC 482


>gi|158534055 round spermatid basic protein 1-like [Homo sapiens]
          Length = 846

 Score = 32.3 bits (72), Expect = 0.52
 Identities = 22/76 (28%), Positives = 30/76 (39%)

Query: 72  PELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRI 131
           P  AP+P       +  +   S  PS  SS SS S         +      Q  PR + +
Sbjct: 71  PPAAPSPQSYGSPASWSFAPLSAAPSPSSSRSSFSFSAGTAVPSSASASLSQPVPRKLLV 130

Query: 132 QPKVVHCQPLDLKGPA 147
            P ++H QP  L  PA
Sbjct: 131 PPTLLHAQPHHLLLPA 146


>gi|60593036 keratin associated protein 5-3 [Homo sapiens]
          Length = 238

 Score = 32.3 bits (72), Expect = 0.52
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 20/71 (28%)

Query: 162 CGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCAD 221
           CG C C +C+          C + C CS+      G+  C        C     + SC  
Sbjct: 121 CGSCGCSQCS----------CYKPCCCSS----GCGSSCCQSS----CCKPSCSQSSCC- 161

Query: 222 HPCSCSRSNCC 232
            PC CS+S+CC
Sbjct: 162 KPC-CSQSSCC 171



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 20/78 (25%), Positives = 30/78 (38%), Gaps = 7/78 (8%)

Query: 158 LCEACGKCK--CKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDD 215
           +C +CG CK  C  C   +       C   C  S+         +C  +G      ++  
Sbjct: 66  VCGSCGGCKGGCGSCGGSKGGCGSSCCVPVCCSSSCGSCGGSKGVCGFRG-----GSKGG 120

Query: 216 EGSCADHPCSCSRSNCCA 233
            GSC    CSC +  CC+
Sbjct: 121 CGSCGCSQCSCYKPCCCS 138


>gi|60593038 keratin associated protein 5-4 [Homo sapiens]
          Length = 288

 Score = 32.3 bits (72), Expect = 0.52
 Identities = 19/74 (25%), Positives = 28/74 (37%), Gaps = 17/74 (22%)

Query: 162 CGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCAD 221
           CG C C +C+          C + C CS+      G+  C        C++     SC  
Sbjct: 191 CGSCGCSQCS----------CCKPCCCSS----GCGSSCCQSSCCKPCCSSSGCGSSCCQ 236

Query: 222 HPCS---CSRSNCC 232
             C    C +S+CC
Sbjct: 237 SSCCKPYCCQSSCC 250


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 32.0 bits (71), Expect = 0.68
 Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 13/79 (16%)

Query: 158  LCEACGKCKCKE----CASPRTLPSCWVCNQEC-LCSAQTLVNYGTCMCLVQGIFYHC-- 210
            LC+A G+C  ++    C  P        C QE   C AQ   + GTC   + G    C  
Sbjct: 1054 LCQAGGQCVDEDSSHYCVCPEGRTGSH-CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP 1112

Query: 211  -----TNEDDEGSCADHPC 224
                   EDD   CA  PC
Sbjct: 1113 GYNGDNCEDDVDECASQPC 1131


>gi|61743980 stabilin 2 precursor [Homo sapiens]
          Length = 2551

 Score = 32.0 bits (71), Expect = 0.68
 Identities = 33/133 (24%), Positives = 45/133 (33%), Gaps = 20/133 (15%)

Query: 163  GKCKCKECASPRTLPSCWV------CNQECLC----SAQTLVNYGTCMCLVQGIFYHCTN 212
            G C+C E  S     +C        C+Q C C      Q  +  G+C C V     HC N
Sbjct: 1370 GVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDN 1429

Query: 213  EDDEGSCADHPCSCS---------RSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQR 263
               E +C +  C  S          ++C     F G  ++      C +   GC   A  
Sbjct: 1430 ATTEDNC-NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADC 1488

Query: 264  GYDRLRRPGCRCK 276
                  R  C CK
Sbjct: 1489 KRTTPGRRVCTCK 1501


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,780,349
Number of Sequences: 37866
Number of extensions: 788344
Number of successful extensions: 3101
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 2897
Number of HSP's gapped (non-prelim): 274
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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