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Search of human proteins with 188528648
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
(4242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 8858 0.0
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 1388 0.0
gi|153946395 tenascin C precursor [Homo sapiens] 946 0.0
gi|157384973 tenascin R [Homo sapiens] 532 e-150
gi|62988324 tenascin N [Homo sapiens] 474 e-132
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 338 7e-92
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 327 2e-88
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 313 3e-84
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 308 6e-83
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 306 3e-82
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 291 1e-77
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 289 5e-77
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 285 9e-76
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 283 3e-75
gi|148833508 notch1 preproprotein [Homo sapiens] 282 4e-75
gi|134244285 Notch homolog 3 [Homo sapiens] 273 2e-72
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 265 6e-70
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 260 2e-68
gi|24041035 notch 2 preproprotein [Homo sapiens] 253 4e-66
gi|55770876 notch4 preproprotein [Homo sapiens] 251 8e-66
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 235 8e-61
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 234 2e-60
gi|4557679 jagged 1 precursor [Homo sapiens] 233 3e-60
gi|122937283 6720455I24Rik homolog [Homo sapiens] 231 9e-60
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 222 7e-57
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 220 2e-56
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 212 6e-54
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 205 7e-52
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 205 7e-52
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 205 7e-52
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 8858 bits (22984), Expect = 0.0
Identities = 4242/4242 (100%), Positives = 4242/4242 (100%)
Query: 1 MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLY 60
MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLY
Sbjct: 1 MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLY 60
Query: 61 EHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQ 120
EHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQ
Sbjct: 61 EHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQ 120
Query: 121 CTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSP 180
CTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSP
Sbjct: 121 CTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSP 180
Query: 181 PSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFS 240
PSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFS
Sbjct: 181 PSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFS 240
Query: 241 GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPG 300
GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPG
Sbjct: 241 GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPG 300
Query: 301 YTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW 360
YTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW
Sbjct: 301 YTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW 360
Query: 361 PGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCV 420
PGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCV
Sbjct: 361 PGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCV 420
Query: 421 CWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGR 480
CWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGR
Sbjct: 421 CWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGR 480
Query: 481 CMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCED 540
CMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCED
Sbjct: 481 CMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCED 540
Query: 541 GVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVC 600
GVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVC
Sbjct: 541 GVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVC 600
Query: 601 QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRG 660
QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRG
Sbjct: 601 QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRG 660
Query: 661 RCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCP 720
RCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCP
Sbjct: 661 RCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCP 720
Query: 721 GDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYE 780
GDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYE
Sbjct: 721 GDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYE 780
Query: 781 IQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMI 840
IQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMI
Sbjct: 781 IQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMI 840
Query: 841 DGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMP 900
DGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMP
Sbjct: 841 DGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMP 900
Query: 901 GVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRP 960
GVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRP
Sbjct: 901 GVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRP 960
Query: 961 QELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPP 1020
QELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPP
Sbjct: 961 QELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPP 1020
Query: 1021 PPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLL 1080
PPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLL
Sbjct: 1021 PPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLL 1080
Query: 1081 RWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG 1140
RWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG
Sbjct: 1081 RWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG 1140
Query: 1141 PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRP 1200
PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRP
Sbjct: 1141 PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRP 1200
Query: 1201 QVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLE 1260
QVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLE
Sbjct: 1201 QVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLE 1260
Query: 1261 QPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLD 1320
QPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLD
Sbjct: 1261 QPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLD 1320
Query: 1321 PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTV 1380
PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTV
Sbjct: 1321 PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTV 1380
Query: 1381 TGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHL 1440
TGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHL
Sbjct: 1381 TGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHL 1440
Query: 1441 YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQ 1500
YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQ
Sbjct: 1441 YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQ 1500
Query: 1501 FDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVT 1560
FDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVT
Sbjct: 1501 FDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVT 1560
Query: 1561 APLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQV 1620
APLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQV
Sbjct: 1561 APLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQV 1620
Query: 1621 VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL 1680
VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL
Sbjct: 1621 VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL 1680
Query: 1681 WVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFL 1740
WVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFL
Sbjct: 1681 WVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFL 1740
Query: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800
LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE
Sbjct: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800
Query: 1801 GQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
GQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA
Sbjct: 1801 GQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
Query: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920
ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG
Sbjct: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920
Query: 1921 QLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTA 1980
QLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTA
Sbjct: 1921 QLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTA 1980
Query: 1981 TPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGV 2040
TPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGV
Sbjct: 1981 TPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGV 2040
Query: 2041 TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE 2100
TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE
Sbjct: 2041 TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE 2100
Query: 2101 LTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYK 2160
LTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYK
Sbjct: 2101 LTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYK 2160
Query: 2161 MHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQ 2220
MHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQ
Sbjct: 2161 MHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQ 2220
Query: 2221 FDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLT 2280
FDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLT
Sbjct: 2221 FDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLT 2280
Query: 2281 APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG 2340
APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG
Sbjct: 2281 APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG 2340
Query: 2341 DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTE 2400
DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTE
Sbjct: 2341 DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTE 2400
Query: 2401 PSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGE 2460
PSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGE
Sbjct: 2401 PSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGE 2460
Query: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP
Sbjct: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGL 2580
EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGL
Sbjct: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGL 2580
Query: 2581 EPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDAT 2640
EPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDAT
Sbjct: 2581 EPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDAT 2640
Query: 2641 PDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFH 2700
PDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFH
Sbjct: 2641 PDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFH 2700
Query: 2701 GGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ 2760
GGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ
Sbjct: 2701 GGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ 2760
Query: 2761 GHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVG 2820
GHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVG
Sbjct: 2761 GHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVG 2820
Query: 2821 VTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGD 2880
VTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGD
Sbjct: 2821 VTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGD 2880
Query: 2881 GQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEP 2940
GQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEP
Sbjct: 2881 GQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEP 2940
Query: 2941 STEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEE 3000
STEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEE
Sbjct: 2941 STEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEE 3000
Query: 3001 SEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPR 3060
SEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPR
Sbjct: 3001 SEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPR 3060
Query: 3061 LGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDH 3120
LGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDH
Sbjct: 3061 LGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDH 3120
Query: 3121 KYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSL 3180
KYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSL
Sbjct: 3121 KYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSL 3180
Query: 3181 SLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR 3240
SLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR
Sbjct: 3181 SLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR 3240
Query: 3241 VGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ 3300
VGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ
Sbjct: 3241 VGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ 3300
Query: 3301 PQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELT 3360
PQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELT
Sbjct: 3301 PQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELT 3360
Query: 3361 VTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFL 3420
VTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFL
Sbjct: 3361 VTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFL 3420
Query: 3421 LYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQ 3480
LYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQ
Sbjct: 3421 LYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQ 3480
Query: 3481 YRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTP 3540
YRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTP
Sbjct: 3481 YRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTP 3540
Query: 3541 APELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLV 3600
APELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLV
Sbjct: 3541 APELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLV 3600
Query: 3601 DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLS 3660
DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLS
Sbjct: 3601 DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLS 3660
Query: 3661 VTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRD 3720
VTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRD
Sbjct: 3661 VTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRD 3720
Query: 3721 LRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSR 3780
LRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSR
Sbjct: 3721 LRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSR 3780
Query: 3781 ADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT 3840
ADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT
Sbjct: 3781 ADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT 3840
Query: 3841 TVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHD 3900
TVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHD
Sbjct: 3841 TVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHD 3900
Query: 3901 LVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAG 3960
LVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAG
Sbjct: 3901 LVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAG 3960
Query: 3961 YLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGL 4020
YLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGL
Sbjct: 3961 YLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGL 4020
Query: 4021 RIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDF 4080
RIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDF
Sbjct: 4021 RIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDF 4080
Query: 4081 WRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAA 4140
WRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAA
Sbjct: 4081 WRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAA 4140
Query: 4141 EYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNG 4200
EYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNG
Sbjct: 4141 EYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNG 4200
Query: 4201 LYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG 4242
LYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG
Sbjct: 4201 LYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG 4242
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 1388 bits (3593), Expect = 0.0
Identities = 673/673 (100%), Positives = 673/673 (100%)
Query: 3570 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 3629
MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 3630 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 3689
RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 3690 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 3749
PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 3750 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 3809
LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK
Sbjct: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 240
Query: 3810 LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 3869
LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP
Sbjct: 241 LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 300
Query: 3870 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 3929
VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT
Sbjct: 301 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 360
Query: 3930 GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 3989
GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL
Sbjct: 361 GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 420
Query: 3990 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 4049
FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN
Sbjct: 421 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 480
Query: 4050 RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 4109
RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT
Sbjct: 481 RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 540
Query: 4110 QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 4169
QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR
Sbjct: 541 QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 600
Query: 4170 DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 4229
DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK
Sbjct: 601 DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 660
Query: 4230 LRPRNFRSPAGGG 4242
LRPRNFRSPAGGG
Sbjct: 661 LRPRNFRSPAGGG 673
Score = 232 bits (592), Expect = 5e-60
Identities = 171/526 (32%), Positives = 251/526 (47%), Gaps = 48/526 (9%)
Query: 3463 LRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGK 3522
+RLSW+VAQGPFDSFVVQY DT+GQP+A+ V DQ + + LEP Y+FLLYGL GK
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 3523 RLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFD 3582
RLGP+SA G T PA + + E+ PRL L+VTD T S+RL+W G FD
Sbjct: 61 RLGPLSAEGTTGL---APAGQTSEES-----RPRLSQLSVTDVTTSSLRLNWEAPPGAFD 112
Query: 3583 SFVVQYE-------DTNGQP---QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 3632
SF++++ + + +P + L+V G + ++ L T Y LYGL G
Sbjct: 113 SFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLR-----G 167
Query: 3633 PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 3692
P A+ G A ES PR L +++ +S ++NW PP DSF + + +
Sbjct: 168 PHKADSIQGTARTLSPVLES-PR--DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADG 224
Query: 3693 STLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSP 3752
EP + + V G + L+ L G Y +T+ +RG +++ + G L+
Sbjct: 225 G--EP-------QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTG---FLTT 272
Query: 3753 VLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQG 3812
V + P L+ + E A ++W PP + D++ V A G P + G A L
Sbjct: 273 VPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV-TAPGAPPLQAETPGSAVDYPLHD 331
Query: 3813 LIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW-KPPQNPVD 3871
L+ Y TV +RG + P + TT + P L A +T A+L W +PP P
Sbjct: 332 LVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAG 391
Query: 3872 TYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG- 3930
Y + PG + PG + L L T+Y A ++ + G +L P S +FTTG
Sbjct: 392 -YLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGG 450
Query: 3931 --LEAPRD----LEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGG 3970
+ PRD ++ RT+ + RP T GG
Sbjct: 451 LRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGG 496
Score = 195 bits (496), Expect = 7e-49
Identities = 145/501 (28%), Positives = 220/501 (43%), Gaps = 54/501 (10%)
Query: 2966 LSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQ 3025
+ LSW++ QG FDSF VQY+D +G+PQ + V G++S++ + GLEP Y+ LYGLHEG+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 3026 RVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQF 3085
R+GP+SA G T +T++ +PRL +L+VTD T SL L+W P G F
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEES---------RPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
Query: 3086 DHFLVQYRNGDGQP------------KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 3133
D FL+++ G P + + VPG + L Y + LYG G
Sbjct: 112 DSFLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPH 169
Query: 3134 RVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 3193
+ + T SP E+P + E+ T S ++W P R DS
Sbjct: 170 KADSIQGTA----RTLSP------VLESPRDLQFSEIRET-----SAKVNWMPPPSRADS 214
Query: 3194 FTVQYKDRD-GQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAP 3252
F V Y+ D G+PQ V+V G+ + GL PG +Y++ + + + P++ T P
Sbjct: 215 FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP 274
Query: 3253 -LPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLR 3311
PT +L +T L W Q P D++ VQ P G
Sbjct: 275 DGPT---------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAV 325
Query: 3312 AVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGL 3371
+ L Y + GL+ P + T + +PR +L + TP + L
Sbjct: 326 DYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLE---APR--DLEAKEVTPRTALL 380
Query: 3372 SWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLG 3431
+WT P +++ + G+ Q + + + GL PS Y L + G+ L
Sbjct: 381 TWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLP 440
Query: 3432 PISADSTTAPLEKELPPHLGE 3452
P+S TT L P GE
Sbjct: 441 PVSTSFTTGGLRIPFPRDCGE 461
Score = 191 bits (485), Expect = 1e-47
Identities = 145/476 (30%), Positives = 216/476 (45%), Gaps = 41/476 (8%)
Query: 3180 LSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQ 3239
+ LSW+V QG FDSF VQY+D +GQPQ + V G++S++ + GLEP Y+ LYGLHEG+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 3240 RVGPVSTVGITAPLP---TPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQY-- 3294
R+GP+S G T P T PRL +L+V VT+ S+ L+W G FDSFL+++
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 3295 -RDAQGQPQAVP-------VSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEART 3346
+ +P P V G + + L Y L+GL+ + + ART
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 3347 APDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKD-GRLQVVPVAANQRE 3405
SPR +L ++ S ++W P DSF V Y+ D G Q V V R
Sbjct: 181 LSPVLESPR--DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238
Query: 3406 VTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRL 3465
+QGL P +Y + + G + P++ TT P + P L L + E + L
Sbjct: 239 QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP---DGPTQLRALNLTEGFAV---L 292
Query: 3466 SWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLG 3525
W Q P D++ VQ P A P+ A+ PG + L+ L+
Sbjct: 293 HWKPPQNPVDTYDVQVT----APGAPPLQAE---------TPGSAVDYPLHDLVLHTNY- 338
Query: 3526 PVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFV 3585
+ G+ P +PA E P + L + TP + L+W+ ++
Sbjct: 339 TATVRGLRGPNLTSPASITFTTGLEAPRD-----LEAKEVTPRTALLTWTEPPVRPAGYL 393
Query: 3586 VQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTG 3641
+ + GQ Q +L+ G + + GL PST Y L + L P+S TTG
Sbjct: 394 LSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
Score = 184 bits (468), Expect = 1e-45
Identities = 155/528 (29%), Positives = 215/528 (40%), Gaps = 83/528 (15%)
Query: 2538 LSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGR 2597
+ LSW+V QG FDSF VQY+D +G+PQA+ V G +SK+ + GLEP Y+ LYGLHEG+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 2598 RLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDH 2657
RLGP+SA G TT P +PRL +L++TD T SL L+W P G FD
Sbjct: 61 RLGPLSAEG-------TTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
Query: 2658 FLVQYRNGDGQP------------KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 2705
FL+++ G P + + VPG + L Y + LYG G +
Sbjct: 114 FLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
Query: 2706 GPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDS 2765
I T SP E P + E+ T S ++W P DS
Sbjct: 172 DSIQ------GTARTLSP------VLESPRDLQFSEIRET-----SAKVNWMPPPSRADS 214
Query: 2766 FTVQYKDRD-GRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTED 2824
F V Y+ D G PQ ++V G+ + GL PG +Y+ V VS G +
Sbjct: 215 FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYE-----------VTVVSVRGF--E 261
Query: 2825 EAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPK 2884
E+E TT P+ P + R LT A L W P+ D + VQ P
Sbjct: 262 ESEPLTGFLTTVPDGPTQLRALNLTEGFAV-----LHWKPPQNPVDTYDVQVTAPGAPPL 316
Query: 2885 VVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEA 2944
PG + L Y + G G P S+ T EA
Sbjct: 317 QAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT------------GLEA 364
Query: 2945 PEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVT 3004
P +L +P + L+WT P R + + + G+ Q + + G +
Sbjct: 365 PR--------DLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQ 416
Query: 3005 VGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTA------PKDEAETTQ 3046
+ GL P Y L + + PVS T P+D E Q
Sbjct: 417 LLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQ 464
Score = 177 bits (448), Expect = 3e-43
Identities = 142/516 (27%), Positives = 205/516 (39%), Gaps = 96/516 (18%)
Query: 2111 LSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGR 2170
+ LSW+V QG FDSF VQY+D +G+PQ + V G++S++ + GLEP Y+ LYGLHEG+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 2171 RVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKN 2230
R+GP+SA G T + ++ RL Q++V D+T+ SL L+W P G FD FL++F
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF-- 118
Query: 2231 GDGQP------------KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVG 2278
G P + + VPG + L Y + LYG G +
Sbjct: 119 GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA------- 171
Query: 2279 LTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYK 2338
D A T P E P + E+ T A ++W P + D F V Y+
Sbjct: 172 ------DSIQGTARTLSPVLESPRDLQFSEIRETSA-----KVNWMPPPSRADSFKVSYQ 220
Query: 2339 NGD-GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPS 2397
D G+P++ +V G + GL P +Y+ V+ + V EE
Sbjct: 221 LADGGEPQSVQVDGQARTQKLQGLIPGARYE--------------VTVVSVRGFEE---- 262
Query: 2398 PTEPSMEAPEPPEEPLLGELTVTGSSPDSLS----------LSWTVPQGRFDSFTVQYKD 2447
EPL G LT P L L W PQ D++ VQ
Sbjct: 263 ------------SEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTA 310
Query: 2448 RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETP 2507
P G + + L Y + GL P S T
Sbjct: 311 PGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT---------- 360
Query: 2508 SPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVR 2567
G EAP +L +P + L+WT P R + + + G+ Q +
Sbjct: 361 -----GLEAP--------RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL 407
Query: 2568 VGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVS 2603
+ G + + GL P Y L + L PVS
Sbjct: 408 LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443
Score = 175 bits (443), Expect = 1e-42
Identities = 148/576 (25%), Positives = 218/576 (37%), Gaps = 87/576 (15%)
Query: 1897 LHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGK 1956
+ LSW V +G FDSF +QY D +GQ Q + + GD++ I +SGLE Y LYG +GK
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1957 HVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDH 2016
+GP+ E T P +PRL +L+VTD T SL L+W P G FD
Sbjct: 61 RLGPLSAEGTT-------GLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
Query: 2017 FLVQYRNGDGQP------------KAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRM 2064
FL+++ G P + + VPG + L Y + LYG G +
Sbjct: 114 FLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
Query: 2065 GPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2124
+ + T P +E+P +L + S ++W P R DS
Sbjct: 172 DSI---------QGTARTLSPVLESPR--------DLQFSEIRETSAKVNWMPPPSRADS 214
Query: 2125 FTVQYKDRD-GRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAP 2183
F V Y+ D G PQ V+V G+ + GL PG +Y++ + + P++ T
Sbjct: 215 FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTV- 273
Query: 2184 EEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGH 2243
PD P Q+ ++T L W P+ D + VQ P PG
Sbjct: 274 ----PDGPT------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGS 323
Query: 2244 EDGVTISGLEPDHKYKMNLYGFHGGQRVGPVS---AVGLTAPGKDEEMAPASTEPPTPEP 2300
+ L Y + G G P S GL AP
Sbjct: 324 AVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAP------------------ 365
Query: 2301 PIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISG 2360
+L + TP + L+WT P + +L+ + GQ + +PG + G
Sbjct: 366 ------RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLG 419
Query: 2361 LEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVT 2420
L P Y L G + PVS T P P + E + +
Sbjct: 420 LFPSTSYNARLQAMWGQSLLPPVST-SFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLN 478
Query: 2421 GSSPDSLSL---------SWTVPQGRFDSFTVQYKD 2447
G+ L++ W V Q R D T ++D
Sbjct: 479 GNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
Score = 174 bits (440), Expect = 2e-42
Identities = 136/491 (27%), Positives = 216/491 (43%), Gaps = 55/491 (11%)
Query: 1388 LSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQ 1447
+ L W+V QG FDSF VQY+D +G+P+A+ V G +S++ + GLEP Y+ LYGLHEG+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1448 RVGPVSAVGVT--APQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFI 1505
R+GP+SA G T AP + T PRL +L+VTDVT +S+ L+W P G FDSF+
Sbjct: 61 RLGPLSAEGTTGLAPAGQ-----TSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL 115
Query: 1506 VQY---KDKDGQPQVVP-------VAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLS 1555
+++ +P P V + + +L Y + +YGL + +
Sbjct: 116 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175
Query: 1556 VVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRD 1615
T +P E+ + +L ++I S ++W P DSF V Y+ D
Sbjct: 176 GTARTL----SPVLESPR--------DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD 223
Query: 1616 -GQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAP 1674
G+PQ V V R + L P +Y+ + ++ + P++ TV P P
Sbjct: 224 GGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTV------PDGP 277
Query: 1675 PRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQV-VPVEGHERSVTVTPLDA 1733
+L L +T+ L W P+ D++ VQ P + G + L
Sbjct: 278 TQLRALNLTE---GFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVL 334
Query: 1734 GRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVG 1793
Y + GL G P + T TG + P +L+ VT +
Sbjct: 335 HTNYTATVRGLRGPNLTSPASITFT---------TGLEAP------RDLEAKEVTPRTAL 379
Query: 1794 LSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRV 1853
L+WT P + +++ + GQ Q + + G + + GL P+ Y L + +
Sbjct: 380 LTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLL 439
Query: 1854 GPISAVAITAG 1864
P+S T G
Sbjct: 440 PPVSTSFTTGG 450
Score = 169 bits (429), Expect = 4e-41
Identities = 145/520 (27%), Positives = 218/520 (41%), Gaps = 69/520 (13%)
Query: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQ 1336
+RLSW+VAQGPFDSF+VQY+D GQPQA+ V GD++++ + GL+P Y+ LYGL +
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1337 RVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQ 1396
R+GP S + T G + ES P L +L+VT + SL L W P
Sbjct: 61 RLGPLS----------AEGTTGLAPAGQTSEES--RPRLSQLSVTDVTTSSLRLNWEAPP 108
Query: 1397 GSFDSF----------TVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEG 1446
G+FDSF T++ R R + V G + L G Y + LYGL
Sbjct: 109 GAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGP 168
Query: 1447 QRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIV 1506
+ + T P ESP + + E+ T S ++W P + DSF V
Sbjct: 169 HKADSIQGTART------LSPVLESPRDLQFSEIRET-----SAKVNWMPPPSRADSFKV 217
Query: 1507 QYKDKD-GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565
Y+ D G+PQ V V R + L P +Y++ + + + PL+ + T P P
Sbjct: 218 SYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGP 277
Query: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAA 1625
+L ++T L W P+ D++ VQ P
Sbjct: 278 T---------------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPG 322
Query: 1626 DQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685
+ + DL Y + G++ SP S+ T G +P +L +
Sbjct: 323 SAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI---TFTTGLEAP------RDLEAKEV 373
Query: 1686 TPDSLRLSWTVPEGQFDSFVVQFKDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744
TP + L+WT P + +++ F G Q + + G S + L Y L +
Sbjct: 374 TPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAM 433
Query: 1745 LGKKRHGPLTADGTTEARSAMDDTGTKRPPKPR-LGEELQ 1783
G+ P++ T TG R P PR GEE+Q
Sbjct: 434 WGQSLLPPVSTSFT---------TGGLRIPFPRDCGEEMQ 464
Score = 169 bits (429), Expect = 4e-41
Identities = 137/490 (27%), Positives = 210/490 (42%), Gaps = 58/490 (11%)
Query: 1492 LSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRM 1551
LSW+V +G FDSF+VQY+D +GQPQ + V DQ ++ + LEP Y+ +YGLH+G+R+
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
Query: 1552 GPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY 1611
GPLS T P +E S+ PRL +L+VTD+T S+ L+W P G FDSF++++
Sbjct: 63 GPLSAEGTTGLAPAGQTSEESR----PRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
Query: 1612 ---KDRDGQPQVVPVAADQREVTIP---------DLEPSRKYKFLLFGIQDGKRRSPVSV 1659
+P P+ QRE+ +P DL Y L+G++ + +
Sbjct: 119 GVPSPSTLEPHPRPLL--QRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQG 176
Query: 1660 EAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVV 1717
A+T++ SP +L ++ S +++W P + DSF V ++ DG PQ V
Sbjct: 177 TARTLSPVLESP------RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSV 230
Query: 1718 PVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPR 1777
V+G R+ + L G +Y + + G + PLT TT P P
Sbjct: 231 QVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTV------------PDGP- 277
Query: 1778 LGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPA 1837
+L+ +T+ L W P+ D++ VQ P GS + + L
Sbjct: 278 --TQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLH 335
Query: 1838 HRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTL 1897
Y + GL P S + T G E AP +L +E T T
Sbjct: 336 TNYTATVRGLRGPNLTSPAS-ITFTTGLE------------APR----DLEAKEVTPRTA 378
Query: 1898 HLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKH 1957
L+W + + + GQ Q + + G L GL Y L
Sbjct: 379 LLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSL 438
Query: 1958 VGPVHVEALT 1967
+ PV T
Sbjct: 439 LPPVSTSFTT 448
Score = 166 bits (421), Expect = 3e-40
Identities = 134/506 (26%), Positives = 212/506 (41%), Gaps = 75/506 (14%)
Query: 1175 LHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKK 1234
+ LSW+V +G FD+F+VQY D +G+PQ + V+G + ++S L+P YRF L+G+ K
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1235 RYGPLTADGTT----APERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDS 1290
R GPL+A+GTT A + EE +P L +L+VT VT SLRL+W G FDS
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEE-------SRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
Query: 1291 FMVQY---KDAQGQPQAVPVAGDENEVTVPG---------LDPDRKYKMNLYGLRGRQRV 1338
F++++ + +P P+ + E+ VPG L Y + LYGLRG +
Sbjct: 114 FLLRFGVPSPSTLEPHPRPLL--QRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
Query: 1339 GPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGS 1398
A+T + ESP + E+ T S + W P
Sbjct: 172 DSIQGTARTL---------------SPVLESPRDLQFSEIRET-----SAKVNWMPPPSR 211
Query: 1399 FDSFTVQYKDRD-GRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGV 1457
DSF V Y+ D G P++V+V G+ + GL PG +Y++ + + + P++
Sbjct: 212 ADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT 271
Query: 1458 TAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQV 1517
T P + P +L ++T L W P+ D++ VQ P
Sbjct: 272 TVP---------DGPT-----QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQ 317
Query: 1518 VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLE 1577
+ +++L Y + GL P S+ T P
Sbjct: 318 AETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPR----------- 366
Query: 1578 PRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEP 1637
+L ++TP + L+WT P +++ + GQ Q + + + L P
Sbjct: 367 ----DLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFP 422
Query: 1638 SRKYKFLLFGIQDGKRRSPVSVEAKT 1663
S Y L + PVS T
Sbjct: 423 STSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 164 bits (414), Expect = 2e-39
Identities = 135/497 (27%), Positives = 204/497 (41%), Gaps = 61/497 (12%)
Query: 1080 LRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRH 1139
L W+V +G FDSFV+QY+D +GQPQ + V+G Q +I+ L+P Y+F+LYG KR
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
Query: 1140 GPLVAEAK--ILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY---- 1193
GPL AE + P S + P L L VTD T SL L+W P G FD+F++++
Sbjct: 63 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 122
Query: 1194 ------RDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAP 1247
R + + V G S V+ L Y TL+G+ GP AD
Sbjct: 123 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLR-----GPHKADSIQGT 177
Query: 1248 ERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQ-GQPQAVP 1306
R P LE P +L + + S +++W DSF V Y+ A G+PQ+V
Sbjct: 178 ARTLSP----VLESP--RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231
Query: 1307 VAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEA 1366
V G + GL P +Y++ + +RG +E+ T T
Sbjct: 232 VDGQARTQKLQGLIPGARYEVTVVSVRG------------------FEESEPLTGFLTTV 273
Query: 1367 PESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVT 1426
P+ P +L + L W PQ D++ VQ P G +
Sbjct: 274 PDGPT-----QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYP 328
Query: 1427 VGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVT 1486
+ L Y + GL GP +T+P E+P +L +VT
Sbjct: 329 LHDLVLHTNYTATVRGLR-----GP----NLTSPASITFTTGLEAP-----RDLEAKEVT 374
Query: 1487 PNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLH 1546
P + L+WT P + +++ + GQ Q + + + L P Y + +
Sbjct: 375 PRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMW 434
Query: 1547 DGQRMGPLSVVIVTAPL 1563
+ P+S T L
Sbjct: 435 GQSLLPPVSTSFTTGGL 451
Score = 163 bits (412), Expect = 4e-39
Identities = 146/577 (25%), Positives = 226/577 (39%), Gaps = 84/577 (14%)
Query: 2003 LSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQ 2062
+ LSW+V +G FD F+VQY + +GQP+A+ V G + + ISGLEP Y+ LYG H G+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 2063 RMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRF 2122
R+GP+S G T P+ + E + P L +L+VT + SL L+W P G F
Sbjct: 61 RLGPLSAEGTTG--------LAPAGQTSEES-RPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
Query: 2123 DSFTVQY-------KDRDGRPQVVR---VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2172
DSF +++ + RP + R V G + L G Y + LYGL +
Sbjct: 112 DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
Query: 2173 GPVSAVGVT-APEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNG 2231
+ T +P ESP + +I S ++W P + D F V ++
Sbjct: 172 DSIQGTARTLSPVLESP---------RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLA 222
Query: 2232 D-GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAP 2290
D G+P++V+V G + GL P +Y++ + G + P++ T P
Sbjct: 223 DGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP-------- 274
Query: 2291 ASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVP 2350
+ PT +L + T L W P+ D + VQ P P
Sbjct: 275 ---DGPT----------QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETP 321
Query: 2351 GHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPE 2410
G + L Y + G G P S T +EAP
Sbjct: 322 GSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT------------GLEAPR--- 366
Query: 2411 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLE 2470
+L +P + L+WT P R + + + G+ Q + + G + + GL
Sbjct: 367 -----DLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 421
Query: 2471 PGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTV 2530
P Y L + + PVST T P P + G E + +
Sbjct: 422 PSTSYNARLQAMWGQSLLPPVSTSFTTGGL----RIPFPRDCGEEMQNGAGASRTSTIFL 477
Query: 2531 TGSSPDSLSL---------SWTVPQGRFDSFTVQYKD 2558
G+ L++ W V Q R D T ++D
Sbjct: 478 NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
Score = 159 bits (402), Expect = 6e-38
Identities = 132/466 (28%), Positives = 193/466 (41%), Gaps = 34/466 (7%)
Query: 3074 LSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 3133
+ LSW V +G FD F+VQY + +GQP+A+ V G + + ISGLEP Y+ LYG H G+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 3134 RVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 3193
R+GP+SA G T P+ + E P L +L+VT + SL L+W P G FDS
Sbjct: 61 RLGPLSAEGTT------GLAPAGQTSE-ESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS 113
Query: 3194 F----------TVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGP 3243
F T++ R + + V G + L G Y + LYGL GP
Sbjct: 114 FLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLR-----GP 168
Query: 3244 VSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQ-GQPQ 3302
I T PV +L + + S ++W DSF V Y+ A G+PQ
Sbjct: 169 HKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQ 228
Query: 3303 AVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVT 3362
+V V G R + GL P +Y+ + ++ + P+ T PD R LT
Sbjct: 229 SVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEG 288
Query: 3363 DATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLY 3422
A L W P+ D++ VQ + + + L Y +
Sbjct: 289 FAV-----LHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343
Query: 3423 GLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYR 3482
GL G P S TT E P +L E T + L+WT +++ +
Sbjct: 344 GLRGPNLTSPASITFTTG---LEAP---RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFH 397
Query: 3483 DTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVS 3528
GQ + + + + + L P Y L + G L PVS
Sbjct: 398 TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443
Score = 125 bits (313), Expect = 1e-27
Identities = 119/488 (24%), Positives = 184/488 (37%), Gaps = 56/488 (11%)
Query: 977 LRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPG 1036
+R+ W+ F F ++ G ++ GD + L+ P TPY L+G+ G
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDGDQSKILISGLEPSTPYRFLLYGLHEG 59
Query: 1037 GKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQY 1096
K P+ +G PRL +L+VTD T+ SL L W P G FDSF++++
Sbjct: 60 -KRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
Query: 1097 ----------KDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEA 1146
R + + V G + SAV+ L G Y LYG G + + A
Sbjct: 119 GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
Query: 1147 KILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRD-GRPQVVPV 1205
+ L SP +L ++ S ++W P + D+F V Y+ D G PQ V V
Sbjct: 179 RTLSPVLESP------RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV 232
Query: 1206 EGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLG 1265
+G R+ + L P +Y T+ + + PLT TT P+
Sbjct: 233 DGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPT-------------- 278
Query: 1266 ELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKY 1325
+L +T L W Q P D++ VQ P G + + L Y
Sbjct: 279 QLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNY 338
Query: 1326 KMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSP 1385
+ GLRG P S+ T G EAP +L +P
Sbjct: 339 TATVRGLRGPNLTSPASITFTT---------------GLEAPR--------DLEAKEVTP 375
Query: 1386 DSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHE 1445
+ L WT P + + + G+ + + + G + + GL P Y L +
Sbjct: 376 RTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 435
Query: 1446 GQRVGPVS 1453
+ PVS
Sbjct: 436 QSLLPPVS 443
Score = 102 bits (253), Expect = 1e-20
Identities = 134/577 (23%), Positives = 199/577 (34%), Gaps = 87/577 (15%)
Query: 856 LELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEY-VVTVTAERGR 914
+ L W Q D FVV Y Q L V + L++ L P Y + G+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 915 AVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDET 974
+ P S TG +P G P S S T T
Sbjct: 61 RLG-PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVT----------------------T 97
Query: 975 GRLRVVWTAQPDTFAYFQLRMRVPEGPG---------AHEEVLPGDVRQALVPPPPPGTP 1025
LR+ W A P F F LR VP E ++PG A++ GT
Sbjct: 98 SSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTL 157
Query: 1026 YELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGP----PRLGELTVTDRTSDSLLLR 1081
Y L+L+G+ G +D I + ++ P PR +L ++ S +
Sbjct: 158 YSLTLYGL-RGPHKADSI----------QGTARTLSPVLESPR--DLQFSEIRETSAKVN 204
Query: 1082 WTVPEGEFDSFVIQYKDRD-GQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG 1140
W P DSF + Y+ D G+PQ V V+G R+ + L PG +Y+ + G +
Sbjct: 205 WMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESE 264
Query: 1141 PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRP 1200
PL +P P L L +T+ L W P+ DT+ VQ P
Sbjct: 265 PLTGFLTTVPDG------PTQLRALNLTE---GFAVLHWKPPQNPVDTYDVQVTAPGAPP 315
Query: 1201 QVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLE 1260
G + + L Y T+ G+ P + TT LE
Sbjct: 316 LQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG------------LE 363
Query: 1261 QPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLD 1320
P +L VTP + L+WT +++ + GQ Q + + G + GL
Sbjct: 364 AP--RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 421
Query: 1321 PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTV 1380
P Y L + G+ + P S T P P + G E + +
Sbjct: 422 PSTSYNARLQAMWGQSLLPPVSTSFTTGGL----RIPFPRDCGEEMQNGAGASRTSTIFL 477
Query: 1381 TGSSPDSLSLF---------WTVPQGSFDSFTVQYKD 1408
G+ L++F W V Q D T ++D
Sbjct: 478 NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRD 514
Score = 89.4 bits (220), Expect = 7e-17
Identities = 53/159 (33%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Query: 769 WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSW 828
W P PVD Y++Q T +PP A P SA Y L Y TVR LRG +
Sbjct: 294 WKPPQNPVDTYDVQ---VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNL 350
Query: 829 GLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPP 888
PAS T TT ++ P+DL VTP T L W P +++S+ + G Q + +P
Sbjct: 351 TSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPG 410
Query: 889 EADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG 927
L L P Y + A G+++ P S TG
Sbjct: 411 GITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
Score = 89.0 bits (219), Expect = 9e-17
Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 15/198 (7%)
Query: 760 LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819
+ ET+ + W P P D++++ + +G P + +V A +GL PG Y+VT
Sbjct: 196 IRETSAKVNWMPPPSRADSFKVSY-QLADGGEPQ-SVQVDGQARTQKLQGLIPGARYEVT 253
Query: 820 VRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGN 879
V ++RG P + +TT+ DGP LR + +T L W PQ VD + V + G
Sbjct: 254 VVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGA 313
Query: 880 QRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG-----------S 928
++ E P A L DL+ Y TV RG ++ PAS+ TG
Sbjct: 314 PPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEV 373
Query: 929 SPLGLLGTTDEPP--PSG 944
+P L T EPP P+G
Sbjct: 374 TPRTALLTWTEPPVRPAG 391
Score = 80.9 bits (198), Expect = 3e-14
Identities = 96/415 (23%), Positives = 162/415 (39%), Gaps = 61/415 (14%)
Query: 741 AGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQF-IPTTEGASP---PFTA 796
AG+ E P + + + + +++R W PG D++ ++F +P+ P P
Sbjct: 76 AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQ 135
Query: 797 R---VPSSASAYDQRGLAPGQEYQVTVRALRGTSWG---LPASKTITTMIDGPQDLRVVA 850
R VP + + R L G Y +T+ LRG ++T++ +++ P+DL+
Sbjct: 136 RELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSE 195
Query: 851 VTPTTLELGWLRPQAEVDRFVVSY-VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVT 909
+ T+ ++ W+ P + D F VSY ++ G + ++V +A L L+PG Y VTV
Sbjct: 196 IRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVV 255
Query: 910 AERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVL 969
+ RG S P + G L T P GP+ +LR L
Sbjct: 256 SVRGFEESEPLT----------GFLTTV----PDGPT------------------QLRAL 283
Query: 970 GRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELS 1029
E G + W + + +++ P P E PG + T Y +
Sbjct: 284 NLTE-GFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAET-PGSAVDYPLHDLVLHTNYTAT 341
Query: 1030 LHGV--PPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
+ G+ P P+ G+ P L VT RT+ LL WT P
Sbjct: 342 VRGLRGPNLTSPASITFTTGL-----------EAPRDLEAKEVTPRTA---LLTWTEPPV 387
Query: 1088 EFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPL 1142
+++ + GQ Q + + G S + L P Y L G+ P+
Sbjct: 388 RPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPV 442
Score = 61.2 bits (147), Expect = 2e-08
Identities = 108/493 (21%), Positives = 179/493 (36%), Gaps = 57/493 (11%)
Query: 765 VRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALR 824
+R W+ A GP D++ +Q+ T P V S GL P Y+ + L
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTN---GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLH 57
Query: 825 -----------GTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVS 873
GT+ PA +T L V VT ++L L W P D F+
Sbjct: 58 EGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL-- 115
Query: 874 YVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGL 933
+R VP + TL P ++ + V R AV +R+ T S L L
Sbjct: 116 --------LRFGVP--SPSTLEPHPRPLLQRELMVPGTRHSAVL--RDLRSGTLYS-LTL 162
Query: 934 LGTTDEPPPSGPSTTQGAQAPLLQQ-RPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQ 992
G T +P+L+ R + E+R ET +V W P F+
Sbjct: 163 YGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIR-----ETS-AKVNWMPPPSRADSFK 216
Query: 993 LRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKD 1052
+ ++ +G + G R + PG YE+++ V G + S+P+ G +
Sbjct: 217 VSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSV-RGFEESEPL--TGFLTTV 273
Query: 1053 EEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQ 1112
+ GP +L L +T+ + +L W P+ D++ +Q P G
Sbjct: 274 PD------GPTQLRALNLTEGFA---VLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSA 324
Query: 1113 RSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTP 1172
+ L Y + G G L + A I + +L + TP
Sbjct: 325 VDYPLHDLVLHTNYTATVRGLRGPN----LTSPASITFTTGLEAPR-----DLEAKEVTP 375
Query: 1173 DSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN 1232
+ L+WT P + +++ + G+ Q + + G S + L P Y L +
Sbjct: 376 RTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 435
Query: 1233 KKRYGPLTADGTT 1245
+ P++ TT
Sbjct: 436 QSLLPPVSTSFTT 448
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 946 bits (2446), Expect = 0.0
Identities = 611/2028 (30%), Positives = 911/2028 (44%), Gaps = 246/2028 (12%)
Query: 284 CSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRS 341
CS RG E CVC PG+ G +C CP C RGRC DG+C+CD G+TGEDC +
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
Query: 342 CPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDC-RGRGRCEDGECICDTGYSGDDCG 400
CP DC + G+CV+G C+C+ GY G DCS CP C G C DG C+C G++GDDC
Sbjct: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
Query: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
C +C RGRC + CVC G+TG DC CP DC RGRC NG C C G++GED
Sbjct: 281 KPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGED 340
Query: 461 CGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTG 520
CG +CP C +GRCE G+C+C G+ G DC + CP DC RGRCVDGRC C+ GFTG
Sbjct: 341 CGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTG 400
Query: 521 EDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGY 580
DCG +CP C GHG C +G CVCD GY+GEDCS CP C RG+C++G+CVCE G+
Sbjct: 401 ADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGF 460
Query: 581 SGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDP 640
G DC CPNDC QHG C +G+C+C +GY EDC R CP +C RG C +G+C+C+
Sbjct: 461 KGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCED 520
Query: 641 GYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRA 700
G+TGP CA CP DC G+GRCV G C+CH G+ G+DC ++ CP C + C
Sbjct: 521 GFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQR-----CPSDCHGQGRCVD 575
Query: 701 GQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLL 760
GQC+C EGF G DC +CP DC G+C G C+C +GY+GEDC E P + + +
Sbjct: 576 GQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVT 635
Query: 761 EETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTV 820
EE TV W V Y + + PT EG RVP ++ + L PG EY + V
Sbjct: 636 EE-TVNLAWDNEM-RVTEYLVVYTPTHEGGL-EMQFRVPGDQTSTIIQELEPGVEYFIRV 692
Query: 821 RALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQ 880
A+ +P S + T + P+ L+ ++ T++E+ W + + + + + +
Sbjct: 693 FAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKE 752
Query: 881 ---RVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTT 937
+ + T L PG EY +++ V+ NT L + TT
Sbjct: 753 DEGEITKSLRRPETSYRQTGLAPGQEYEISLHI-----------VKNNTRGPGLKRVTTT 801
Query: 938 DEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRV 997
PS ++ V +T L + W +L +
Sbjct: 802 RLDAPS---------------------QIEVKDVTDTTAL-ITWFKPLAEIDGIELTYGI 839
Query: 998 PEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKP 1056
+ PG + L D Q + P T YE+SL I +G M + K
Sbjct: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSL------------ISRRGDMSSNPAKE 887
Query: 1057 GKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDG----QPQVVPVEGPQ 1112
++G L +T +S+ L W + DS+ I+Y G + V +
Sbjct: 888 TFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQAT 947
Query: 1113 RSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTP 1172
+T L PG +Y + K P A TP +L V++
Sbjct: 948 TKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAA------TELDTPK---DLQVSETAE 998
Query: 1173 DSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN 1232
SL L W P +FD + + Y G+ V + S+V+ L+P +Y L
Sbjct: 999 TSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKG 1058
Query: 1233 KKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFM 1292
+ + P +T + P L LTVT V D LRL+WT A ++ F+
Sbjct: 1059 RHKSKPARVKASTE-------------QAPELENLTVTEVGWDGLRLNWTAADQAYEHFI 1105
Query: 1293 VQYKDAQGQPQA--VPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQ 1350
+Q ++A A + V G V +PGL Y +++YG+ R S A T
Sbjct: 1106 IQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTG-- 1163
Query: 1351 EDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRD 1410
E P LGE+ V D+L L WT P+G+++ F +Q ++ D
Sbjct: 1164 --------------------ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD 1203
Query: 1411 GRPRA--VRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPA 1468
A + V G + GL+ Y + + G+ + P+S +T EE P
Sbjct: 1204 TVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT----EEVPD- 1258
Query: 1469 TESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQV--VPVAADQRE 1526
+G LTVT+V+ +++ L+WT P+G +D F +Q ++ D + + V R
Sbjct: 1259 --------MGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRS 1310
Query: 1527 VTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVT 1586
+ + L Y + ++G G PL+V +VT L P+LG+L V+
Sbjct: 1311 MEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDL--------------PQLGDLAVS 1356
Query: 1587 DITPDSVGLSWTVPEGEFDSFVVQYKD--RDGQPQVVPVAADQREVTIPDLEPSRKYKFL 1644
++ D + L+WT + ++ FV+Q ++ + Q + + R V IP LE + Y+
Sbjct: 1357 EVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVS 1416
Query: 1645 LFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSF 1704
++G+ G R +S EA T P +G L V+D TP+S LSW +G F++F
Sbjct: 1417 IYGVIRGYRTPVLSAEASTAKE--------PEIGNLNVSDITPESFNLSWMATDGIFETF 1468
Query: 1705 VVQFKDKD---GPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEA 1761
++ D + + G ER+ ++ L + L GL R ++A TTEA
Sbjct: 1469 TIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEA 1528
Query: 1762 RSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDG--QPQV 1819
+ E L ++ + +SW E FDSF+V D PQ
Sbjct: 1529 LPLL--------------ENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQE 1574
Query: 1820 VPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPA 1879
+ G+ R++ + GL Y++++ G G + P+ A +T
Sbjct: 1575 FTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA--------------- 1619
Query: 1880 PEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ---LQMVRIGGDR-NDIT 1935
EP + L V +AT LSW EG FD+F ++ D Q L++ + +R DIT
Sbjct: 1620 -EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDIT 1678
Query: 1936 LSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTV 1995
GL Y + LYG S G+ V A T K E+
Sbjct: 1679 --GLREATEYEIELYGISKGRRSQTVSAIATTAMGSPK------------------EVIF 1718
Query: 1996 TDATPDSLSLSWTVPEGQFDHFLVQY-RNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMN 2054
+D T +S ++SW P Q + F + Y G P V V G + + L P +Y ++
Sbjct: 1719 SDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVS 1778
Query: 2055 LYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLS 2114
+ G + PVS TA ++ P VT + DS +L+
Sbjct: 1779 IIAMKGFEESEPVSGSFTTA------------LDGPSG---------LVTANITDSEALA 1817
Query: 2115 -WTVPQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2172
W DS+ + Y + P++ R V G E + LEP +Y + ++
Sbjct: 1818 RWQPAIATVDSYVISYTG-EKVPEITRTVSGNTVEYALTDLEPATEYTLRIFA-----EK 1871
Query: 2173 GPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGD 2232
GP + +TA D+P +T ++ S++ L+W P +L+ +++ D
Sbjct: 1872 GPQKSSTITAKFTTDLDSP------RDLTATEVQSETALLTWRPPRASVTGYLLVYESVD 1925
Query: 2233 GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLT 2280
G K V V +++ L P Y + +G R + + T
Sbjct: 1926 GTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTT 1973
Score = 780 bits (2013), Expect = 0.0
Identities = 544/1736 (31%), Positives = 835/1736 (48%), Gaps = 189/1736 (10%)
Query: 2527 ELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD--RDGRPQAVRVGGQESKVTVRGLEPGR 2584
+L VT + ++++L+W + R + V Y G RV G ++ ++ LEPG
Sbjct: 628 DLVVTEVTEETVNLAWD-NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGV 686
Query: 2585 KYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSL 2644
+Y + ++ + E ++ PVSA V T P P L S+
Sbjct: 687 EYFIRVFAILENKKSIPVSA------------RVATYLPAPE------GLKFKSIKETSV 728
Query: 2645 SLSWTVPEGQFDHFLVQYRNGDGQP-----KAVRVPGHEDGVTISGLEPDHKYKMNLYGF 2699
+ W + F+ + + +RN + + K++R P E +GL P +Y+++L+
Sbjct: 729 EVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRP--ETSYRQTGLAPGQEYEISLHIV 786
Query: 2700 HGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIP 2759
R GP + VT + PS E+ ++T T + ++W P
Sbjct: 787 KNNTR-GP-GLKRVTTTRLDAPSQIEVK-------------DVTDT-----TALITWFKP 826
Query: 2760 QGHFDSFTVQY--KDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
D + Y KD G + + +E++ ++G L+P +Y++ L P
Sbjct: 827 LAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK 886
Query: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYR 2877
T +A P N R+ + T +S++L W + D + ++Y
Sbjct: 887 ETFTTGLDA------------PRNLRRVSQ------TDNSITLEWRNGKAAIDSYRIKYA 928
Query: 2878 N-GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPA 2936
G V VP + T K L G G G I V V +E PA
Sbjct: 929 PISGGDHAEVDVPKSQQATT----------KTTLTGLRPGTEYG-IGVSAVKEDKESNPA 977
Query: 2937 PTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRV 2996
+TE P + L V+ ++ SL+L W P +FD + + Y G+ V++
Sbjct: 978 TINAATELDTPKD------LQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQL 1031
Query: 2997 RGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPP 3056
+ + GLEPG +Y + L +G+ + V +A T QA
Sbjct: 1032 PRNTTSYVLRGLEPGQEYNV-LLTAEKGRHKSKPARV-------KASTEQA--------- 1074
Query: 3057 IKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKA--VRVPGHEDGVTIS 3114
P L LTVT+ D L L+W + ++HF++Q + + A + VPG V I
Sbjct: 1075 --PELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIP 1132
Query: 3115 GLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTG 3174
GL+ Y +++YG G R +SA E ST E P LGE+ V
Sbjct: 1133 GLKAATPYTVSIYGVIQGYRTPVLSA------------EASTG-----ETPNLGEVVVAE 1175
Query: 3175 SSPDSLSLSWTVPQGRFDSFTVQYKDRDG--QPQVVRVRGEESEVTVGGLEPGRKYKMHL 3232
D+L L+WT P+G ++ F +Q ++ D Q + V G + GL+ Y + +
Sbjct: 1176 VGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITI 1235
Query: 3233 YGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLV 3292
G+ + P+S +T +P +G L V V+ D++ L+WT G +D F +
Sbjct: 1236 RGVTQDFSTTPLSVEVLTEEVPD-------MGNLTVTEVSWDALRLNWTTPDGTYDQFTI 1288
Query: 3293 QYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDT 3350
Q ++A +A + V G LR++ + GL Y L G G P+ VE T
Sbjct: 1289 QVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT---- 1344
Query: 3351 KPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKD--KDGRLQVVPVAANQREVTV 3408
+ P+LG+L V++ D + L+WT + ++ FV+Q ++ K Q + + + R V +
Sbjct: 1345 EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDI 1404
Query: 3409 QGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWT 3468
GLE + YR +YG+ R +SA+++TA KE P +G L V++ T S LSW
Sbjct: 1405 PGLEAATPYRVSIYGVIRGYRTPVLSAEASTA---KE--PEIGNLNVSDITPESFNLSWM 1459
Query: 3469 VAQGPFDSFVVQYRDTDGQPRAVP--VAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGP 3526
G F++F ++ D++ V ++ +RT + L P + L GL R
Sbjct: 1460 ATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKT 1519
Query: 3527 VSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVV 3586
+SA TA E P E LT++D P +SW ++ FDSF+V
Sbjct: 1520 ISA---TATTEALPLLEN---------------LTISDINPYGFTVSWMASENAFDSFLV 1561
Query: 3587 QYEDTNG--QPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAP 3644
D+ PQ + G Q K+ + GL Y ++ G +G + PL AE T
Sbjct: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVT---- 1617
Query: 3645 AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQ 3704
E+ P + L V+D T RL+W A G FD+F+L+ + EP L+
Sbjct: 1618 ------EAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQS-EP-----LE 1665
Query: 3705 RELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSE 3764
L+ P + + LR T Y + LYG+ ++ ++ A T + SP+++ FS+
Sbjct: 1666 ITLLAP--ERTRDITGLREATEYEIELYGISKGRRSQTVSAIATT---AMGSPKEVIFSD 1720
Query: 3765 IRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVV 3824
I E SA V+W P ++ +SF+++Y GG P V VDG +L LIPG Y V+++
Sbjct: 1721 ITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSII 1780
Query: 3825 SVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPP 3884
+++GFEESEP++G TT DGP+ L N+T+ A+ W+P VD+Y + T P
Sbjct: 1781 AMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPE 1840
Query: 3885 LQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTP 3944
+ G+ V+Y L DL T YT + +GP +S + FTT L++PRDL A EV
Sbjct: 1841 ITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQS 1900
Query: 3945 RTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 4004
TALLTW P GYLL + + G +E+++ TS+ L L PST Y A++QA+ G
Sbjct: 1901 ETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1960
Query: 4005 QSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDG 4064
+ T FTT GL PFP+DC + M NG S TI+LNG++ L VFCDM +DG
Sbjct: 1961 PLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDG 2020
Query: 4065 GGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGD 4124
GGW+VF RR +G+ +F+++W+ YA GFG+ EFWLG + L+ +T G Y +RVDLR
Sbjct: 2021 GGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHG 2080
Query: 4125 EAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSY 4184
E FA YD F V A Y+L +EGY GTAGDSM+YH+G FS D+D +S + +CA+SY
Sbjct: 2081 ETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSY 2140
Query: 4185 RGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAG 4240
+GA+WYRNCH NL G YG QGV+W+HWKG E S+ F EMKLRP NFR+ G
Sbjct: 2141 KGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEG 2196
Score = 649 bits (1675), Expect = 0.0
Identities = 283/604 (46%), Positives = 355/604 (58%), Gaps = 61/604 (10%)
Query: 55 PSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELV 114
PS EHTV+G E Q+VFTHRIN+P CGC A +V+ L RLE LE LV
Sbjct: 83 PSESFQEHTVDG-ENQIVFTHRINIP-RRACGC-------AAAPDVKELLSRLEELENLV 133
Query: 115 KGLKEQCTGG--CCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTD 172
L+EQCT G CC Q TG+ D R CS G F C
Sbjct: 134 SSLREQCTAGAGCC---LQPATGRLDTRPFCSGRGNFSTEGCG----------------- 173
Query: 173 AEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGV 232
CVC PG+ GP+C P CPG+C RGRC+ G
Sbjct: 174 -----------------------------CVCEPGWKGPNCSEPECPGNCHLRGRCIDGQ 204
Query: 233 CVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQR-GRCE 291
C+C GF+G DCSQ +CP C+ +G+C G C+C GY G DC CP CS+ G C
Sbjct: 205 CICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCV 264
Query: 292 NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGR 351
+G CVC+ G+ G+DC C C RGRC + CVCD G+TGEDC CP DC + GR
Sbjct: 265 DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGR 324
Query: 352 CVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQR 411
C++G C C G+TGEDC TCP C +GRCE+G+C+CD G++G DC + CP DC+ R
Sbjct: 325 CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNR 384
Query: 412 GRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCR 471
GRC DGRC C G+TG DCG CP C G GRC NG CVC+ GY+GEDC CP DC
Sbjct: 385 GRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCH 444
Query: 472 GRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD 531
RGRC G+C+C G+ G DC +CP DC GRCV+G CVC+ G+TGEDC R+CP D
Sbjct: 445 SRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRD 504
Query: 532 CRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCP 591
C GLC DG CVC+ G++G DC+ SCP C G+G+C++G+CVC +G+ G+DC ++CP
Sbjct: 505 CSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCP 564
Query: 592 NDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRM 651
+DC G C DG CIC EG+ DC +CPS+C+ G+C GRC+C+ GY+G C+
Sbjct: 565 SDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVS 624
Query: 652 CPAD 655
P D
Sbjct: 625 PPKD 628
Score = 603 bits (1554), Expect = e-171
Identities = 243/490 (49%), Positives = 308/490 (62%), Gaps = 3/490 (0%)
Query: 196 RCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQ 255
+C G C TG P C G +G CVC G+ GP+CS+ CP C
Sbjct: 139 QCTAGAGCCLQPATGRLDTRPFCSG--RGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHL 196
Query: 256 RGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGC 315
RGRC G+C+CD G+TG+DC +CP C+ +G+C NG C+C GY G DC CP C
Sbjct: 197 RGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPC 256
Query: 316 SQR-GRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCP 374
S+ G C DG CVC G+ G+DC C +C GRCV+ CVC G+TGEDCS CP
Sbjct: 257 SEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICP 316
Query: 375 RDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRA 434
DC RGRC +G C C+ G++G+DCG +CP C+ +GRCE+G+CVC G+ G DC +
Sbjct: 317 NDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKR 376
Query: 435 CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494
CP DC RGRC +G C C+ G++G DCG CP C G GRC +G+C+C GYTG DC
Sbjct: 377 CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQ 436
Query: 495 RACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
CP DC RGRCV+G+CVC GF G DC CP DC HG C +G+CVCD GY+GEDC
Sbjct: 437 LRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDC 496
Query: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSE 614
R CP C RG C+DG+CVCEDG++G DC CPNDC G C +G C+C EG++ +
Sbjct: 497 RDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGK 556
Query: 615 DCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYG 674
DC + CPS+CHG+GRC +G+C+C G+TG C CP+DC G+CV G C+C+ GY
Sbjct: 557 DCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYS 616
Query: 675 GEDCGQEEPP 684
GEDC + PP
Sbjct: 617 GEDCSEVSPP 626
Score = 511 bits (1315), Expect = e-144
Identities = 215/435 (49%), Positives = 272/435 (62%), Gaps = 10/435 (2%)
Query: 316 SQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDG-RCVCWPGYTGEDCSTRTCP 374
S R +C G C TG TR P+ G G +G CVC PG+ G +CS CP
Sbjct: 135 SLREQCTAGAGCCLQPATGR-LDTR--PFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECP 191
Query: 375 RDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRA 434
+C RGRC DG+CICD G++G+DC +CP DCN +G+C +G C+C+ GY G DC
Sbjct: 192 GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREI 251
Query: 435 CPRDC-RGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCG 493
CP C G C +G+CVC+ G++G+DC C +C RGRC C+C G+TG DC
Sbjct: 252 CPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCS 311
Query: 494 TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553
CP DC RGRC++G C C GFTGEDCG CP C G CE+G CVCD G++G D
Sbjct: 312 ELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVD 371
Query: 554 CSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVS 613
CS + CP C RG+C+DGRC C+DG++G DCG +CPN CS HG C +G C+C EGY
Sbjct: 372 CSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTG 431
Query: 614 EDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGY 673
EDCS CP++CH RGRC EG+C+C+ G+ G C+ CP DC GRCV G+C+C GY
Sbjct: 432 EDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGY 491
Query: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGS 733
GEDC + CP C R LC GQCVC +GF GPDCA +CP DC G+G C +G
Sbjct: 492 TGEDCRDRQ-----CPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQ 546
Query: 734 CVCKDGYAGEDCGEE 748
CVC +G+ G+DC E+
Sbjct: 547 CVCHEGFMGKDCKEQ 561
Score = 395 bits (1014), Expect = e-109
Identities = 395/1631 (24%), Positives = 649/1631 (39%), Gaps = 307/1631 (18%)
Query: 1766 DDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQY--KDRDGQPQVVPVE 1823
+D PPK +L VT VT+ +V L+W E + ++V Y G V
Sbjct: 618 EDCSEVSPPK-----DLVVTEVTEETVNLAWD-NEMRVTEYLVVYTPTHEGGLEMQFRVP 671
Query: 1824 GSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPH 1883
G + L+P Y + ++ + K+ P+SA A PAPE
Sbjct: 672 GDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSA-------------RVATYLPAPE-- 716
Query: 1884 LGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLS------ 1937
L + ++ + W + F+++EI + + + + D +IT S
Sbjct: 717 --GLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKE--------DEGEITKSLRRPET 766
Query: 1938 -----GLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGE 1992
GL Y ++L+ + GP ++ +T + PS +
Sbjct: 767 SYRQTGLAPGQEYEISLHIVKNNTR-GP-GLKRVTTTRLDAPS----------------Q 808
Query: 1993 LTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPDHK 2050
+ V D T + ++W P + D + Y ++ G + + E +I L+PD +
Sbjct: 809 IEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTE 868
Query: 2051 YKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDS 2110
Y+++L G P T ++AP L + +S
Sbjct: 869 YEVSLISRRGDMSSNPAKETFTT------------GLDAPR--------NLRRVSQTDNS 908
Query: 2111 LSLSWTVPQGRFDSFTVQYKDRDG----RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGL 2166
++L W + DS+ ++Y G V + ++ T+ GL PG +Y + + +
Sbjct: 909 ITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV 968
Query: 2167 HEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLV 2226
E + P + T E ++P + V + SL+L W P +FD + +
Sbjct: 969 KEDKESNPATINAAT--ELDTPK---------DLQVSETAETSLTLLWKTPLAKFDRYRL 1017
Query: 2227 QFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDE 2286
+ GQ V++P + + GLEP +Y + L G + P
Sbjct: 1018 NYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPA------------ 1065
Query: 2287 EMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKA 2346
ASTE P LE LTVT+ D L L+WT + ++HF++Q + + A
Sbjct: 1066 -RVKASTEQ-------APELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAA 1117
Query: 2347 TR--VPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSME 2404
VPG V I GL+ Y +++YG G R +SA T
Sbjct: 1118 RNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTG-------------- 1163
Query: 2405 APEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEV 2464
E P LGE+ V D+L L+WT P+G ++ F +Q ++ D V ++
Sbjct: 1164 -----ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD------TVEAAQNLT 1212
Query: 2465 TVGGLE----PGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
GGL PG K H T+ + +D TP E TE
Sbjct: 1213 VPGGLRSTDLPGLKAATHY-------------TITIRGVTQDFSTTPLSVEVLTE----- 1254
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQA--VRVGGQESKVTVR 2578
E P +G LTVT S D+L L+WT P G +D FT+Q ++ D +A + V G + +
Sbjct: 1255 EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIP 1314
Query: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
GL G Y + L+G G P++ VTED P+LG+L +++
Sbjct: 1315 GLRAGTPYTVTLHGEVRGHSTRPLAVEVVTED-----------------LPQLGDLAVSE 1357
Query: 2639 ATPDSLSLSWTVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 2696
D L L+WT + ++HF++Q + N + + +PG V I GLE Y++++
Sbjct: 1358 VGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417
Query: 2697 YGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSW 2756
YG G R +S TA +EP +G L V+ +P+S +LSW
Sbjct: 1418 YGVIRGYRTPVLSAEASTA-------------------KEPEIGNLNVSDITPESFNLSW 1458
Query: 2757 TIPQGHFDSFTVQYKDRDGRPQVM--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVG 2814
G F++FT++ D + + + + G E + GL P + ++L GL R
Sbjct: 1459 MATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTK 1518
Query: 2815 PVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLV 2874
+S TT+A+P L LT++D P ++SWM E FD FLV
Sbjct: 1519 TISATA-------TTEALPL----------LENLTISDINPYGFTVSWMASENAFDSFLV 1561
Query: 2875 QYRNGDG--QPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEE 2932
+ P+ + G + + + GL Y++ + GF G + P+ VT A
Sbjct: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA-- 1619
Query: 2933 ETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKD--RDGR 2990
EP + L V+ ++PD LSWT +G FD+F ++ +D +
Sbjct: 1620 -----------------EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE 1662
Query: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTA---PKDEAETTQA 3047
P + + E + GL +Y++ LYG+ +G+R VSA+ TA PK
Sbjct: 1663 PLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPK-------- 1714
Query: 3048 VPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY-RNGDGQPKAVRVPG 3106
E+ +D T +S ++SW P Q + F + Y G P V V G
Sbjct: 1715 ---------------EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
Query: 3107 HEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPL 3166
+ + L P +Y +++ G + PVS T + PS
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSG--------------- 1804
Query: 3167 LGELTVTGSSPDSLSLS-WTVPQGRFDSFTVQYKDRDGQPQVVR-VRGEESEVTVGGLEP 3224
VT + DS +L+ W DS+ + Y + P++ R V G E + LEP
Sbjct: 1805 ----LVTANITDSEALARWQPAIATVDSYVISYTG-EKVPEITRTVSGNTVEYALTDLEP 1859
Query: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
+Y + ++ GP + ITA T L PR +L V S++ L+W +
Sbjct: 1860 ATEYTLRIFA-----EKGPQKSSTITAKFTTDLD-SPR--DLTATEVQSETALLTWRPPR 1911
Query: 3285 GPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEA 3344
+L+ Y G + V V D + +++ L P+ Y + L R +
Sbjct: 1912 ASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIF 1971
Query: 3345 RTAPDTKPSPR 3355
T P P+
Sbjct: 1972 TTIGLLYPFPK 1982
Score = 382 bits (980), Expect = e-105
Identities = 390/1586 (24%), Positives = 639/1586 (40%), Gaps = 271/1586 (17%)
Query: 840 IDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSA--GNQRVRLEVPPEADGTLLTD 897
+ P+DL V VT T+ L W + V ++V Y G ++ VP + T++ +
Sbjct: 623 VSPPKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
Query: 898 LMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQ 957
L PGVEY + V A S P S R T P P G
Sbjct: 682 LEPGVEYFIRVFAILENKKSIPVSARV-----------ATYLPAPEG------------- 717
Query: 958 QRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALV 1017
L+ ET + V W F +++ R +E G++ ++L
Sbjct: 718 --------LKFKSIKETS-VEVEWDPLDIAFETWEIIFR---NMNKEDE---GEITKSLR 762
Query: 1018 PPPP--------PGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPG-KSSGPPRL--- 1065
P PG YE+SLH I+ + PG K RL
Sbjct: 763 RPETSYRQTGLAPGQEYEISLH----------------IVKNNTRGPGLKRVTTTRLDAP 806
Query: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQY--KDRDGQPQVVPVEGPQRSAVITSLDPG 1123
++ V D T + L+ W P E D + Y KD G + + + I +L P
Sbjct: 807 SQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPD 866
Query: 1124 RKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPE 1183
+Y+ L G P A+ D P +L + TD +S+ L W +
Sbjct: 867 TEYEVSLISRRGDMSSNP--AKETFTTGLD----APRNLRRVSQTD---NSITLEWRNGK 917
Query: 1184 GQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADG 1243
D++ ++Y P+ G + + V + TL G+ YG
Sbjct: 918 AAIDSYRIKY---------APISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYG---IGV 965
Query: 1244 TTAPERKEEPPRP--EFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQ 1301
+ E KE P E +L V+ SL L W FD + + Y GQ
Sbjct: 966 SAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQ 1025
Query: 1302 PQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTE 1361
V + + + GL+P ++Y + L +GR + P V A T
Sbjct: 1026 WVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-------------- 1071
Query: 1362 LGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRD--GRPRAVRVG 1419
+APE L LTVT D L L WT +++ F +Q ++ + R + V
Sbjct: 1072 --EQAPE------LENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVP 1123
Query: 1420 GKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGE 1479
G V + GL+ Y + +YG+ +G R +SA T ET P LGE
Sbjct: 1124 GSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTG----ET---------PNLGE 1170
Query: 1480 LTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKD--GQPQVVPVAADQREVTVYNLEPERK 1537
+ V +V +++ L+WT PEG ++ F +Q ++ D Q + V R + L+
Sbjct: 1171 VVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATH 1230
Query: 1538 YKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSW 1597
Y + + G+ PLSV ++T +P +G LTVT+++ D++ L+W
Sbjct: 1231 YTITIRGVTQDFSTTPLSVEVLTEEVPD--------------MGNLTVTEVSWDALRLNW 1276
Query: 1598 TVPEGEFDSFVVQYKDRDGQPQV--VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRS 1655
T P+G +D F +Q ++ D + + V R + IP L Y L G G
Sbjct: 1277 TTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTR 1336
Query: 1656 PVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKD---KD 1712
P++VE T P+LG+L V++ D LRL+WT + ++ FV+Q ++ +
Sbjct: 1337 PLAVEVVTEDL--------PQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVE 1388
Query: 1713 GPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKR 1772
Q + + G R+V + L+A YR +YG++ R L+A+ +T
Sbjct: 1389 AAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAST------------- 1435
Query: 1773 PPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVP--VEGSLREVS 1830
+P +G L V+ +T S LSW +G F++F ++ D + + V + G+ R
Sbjct: 1436 AKEPEIG-NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAH 1494
Query: 1831 VPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVE 1890
+ GL P+ + + L GL R ISA A T P L LT+
Sbjct: 1495 ISGLPPSTDFIVYLSGLAPSIRTKTISATATTEAL----------------PLLENLTIS 1538
Query: 1891 EATSHTLHLSWMVTEGEFDSFEIQYTDRDGQL---QMVRIGGDRNDITLSGLESDHRYLV 1947
+ + +SWM +E FDSF + D G+L Q + G + + L GL + Y V
Sbjct: 1539 DINPYGFTVSWMASENAFDSFLVTVVD-SGKLLDPQEFTLSGTQRKLELRGLITGIGYEV 1597
Query: 1948 TLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSW 2007
+ GF+ G P+ E +T E P + L V+DATPD LSW
Sbjct: 1598 MVSGFTQGHQTKPLRAEIVTEAE-----------------PEVDNLLVSDATPDGFRLSW 1640
Query: 2008 TVPEGQFDHFLVQYRN--GDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMG 2065
T EG FD+F+++ R+ +P + + E I+GL +Y++ LYG G+R
Sbjct: 1641 TADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQ 1700
Query: 2066 PVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSF 2125
VS + TA M +P+ E+ + + +S ++SW P + +SF
Sbjct: 1701 TVSAIATTA------------MGSPK--------EVIFSDITENSATVSWRAPTAQVESF 1740
Query: 2126 TVQYKD-RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPE 2184
+ Y G P +V V G +++ + L PG +Y + + + PVS TA +
Sbjct: 1741 RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD 1800
Query: 2185 EESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVR-VPGH 2243
S G +T S++L+ W D +++ + G+ P+ R V G+
Sbjct: 1801 GPS----------GLVTANITDSEALA-RWQPAIATVDSYVISY-TGEKVPEITRTVSGN 1848
Query: 2244 EDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIK 2303
++ LEP +Y + ++ G Q+ ++ A +T+ +P
Sbjct: 1849 TVEYALTDLEPATEYTLRIFAEKGPQKSSTIT-------------AKFTTDLDSP----- 1890
Query: 2304 PRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEP 2363
+LT T+ ++ L+W P +L+ Y++ DG K V +++ L P
Sbjct: 1891 ---RDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSP 1947
Query: 2364 DNKYKMNLYGFHGGQRVGPVSAIGVT 2389
Y + +G R + I T
Sbjct: 1948 STHYTAKIQALNGPLRSNMIQTIFTT 1973
Score = 377 bits (969), Expect = e-103
Identities = 384/1592 (24%), Positives = 632/1592 (39%), Gaps = 275/1592 (17%)
Query: 1582 ELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQV-VPVAADQREVTIPDLEPSRK 1640
+L VT++T ++V L+W + VV +G ++ V DQ I +LEP +
Sbjct: 628 DLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVE 687
Query: 1641 YKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQ 1700
Y +F I + K+ PVS T AP L + + S+ + W +
Sbjct: 688 YFIRVFAILENKKSIPVSARVATYLP------APEGLKFKSIKET---SVEVEWDPLDIA 738
Query: 1701 FDSFVVQF----KDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTAD 1756
F+++ + F K+ +G + E S T L G++Y L+ ++ GP
Sbjct: 739 FETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH-IVKNNTRGP---- 793
Query: 1757 GTTEARSAMDDTGTKRPPKPRLG--EELQVTTVTQNSVGLSWTVPEGQFDSFVVQY--KD 1812
G KR RL +++V VT + ++W P + D + Y KD
Sbjct: 794 ------------GLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKD 841
Query: 1813 RDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872
G + + + S+ L P Y++ L R G +S+ ET T
Sbjct: 842 VPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLIS-----RRGDMSS------NPAKETFT 890
Query: 1873 TAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRN 1932
T P L T +++ L W + DS+ I+Y G GD
Sbjct: 891 TGLDAPR------NLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISG--------GDHA 936
Query: 1933 DITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGE 1992
++ + + TL G G G + V A+ +E P+ AT K +
Sbjct: 937 EVDVPKSQQATTK-TTLTGLRPGTEYG-IGVSAVKEDKESNPATINAATELDTPK----D 990
Query: 1993 LTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYK 2052
L V++ SL+L W P +FD + + Y GQ V++P + + GLEP +Y
Sbjct: 991 LQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYN 1050
Query: 2053 MNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLS 2112
+ L G + P V T +APE L LTVT D L
Sbjct: 1051 VLLTAEKGRHKSKPARVKASTE-------------QAPE------LENLTVTEVGWDGLR 1091
Query: 2113 LSWTVPQGRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGR 2170
L+WT ++ F +Q ++ + + + V G V + GL+ Y + +YG+ +G
Sbjct: 1092 LNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGY 1151
Query: 2171 RVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKN 2230
R +SA T E+P+ LG++ V ++ D+L L+WT PEG +++F +Q +
Sbjct: 1152 RTPVLSAEASTG---ETPN-------LGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQE 1201
Query: 2231 GDGQPKA--VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEM 2288
D A + VPG + GL+ Y + + G +D
Sbjct: 1202 ADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGV-----------------TQDFST 1244
Query: 2289 APASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKA-- 2346
P S E T E P + LTVT+ + D+L L+WT P+G +D F +Q + D +A
Sbjct: 1245 TPLSVEVLTEE---VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHN 1301
Query: 2347 TRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAP 2406
VPG + I GL Y + L+G G P++ VT
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT----------------- 1344
Query: 2407 EPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD--RDGRPQVVRVGGEESEV 2464
+ P LG+L V+ D L L+WT ++ F +Q ++ + Q + + G V
Sbjct: 1345 --EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAV 1402
Query: 2465 TVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPL 2524
+ GLE Y++ +YG+ G R +S TA +EP
Sbjct: 1403 DIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTA----------------------KEPE 1440
Query: 2525 LGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV--RVGGQESKVTVRGLEP 2582
+G L V+ +P+S +LSW G F++FT++ D + + V + G E + GL P
Sbjct: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
Query: 2583 GRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPD 2642
+ ++L GL R +SA TE P L LT++D P
Sbjct: 1501 STDFIVYLSGLAPSIRTKTISATATTE-----------------ALPLLENLTISDINPY 1543
Query: 2643 SLSLSWTVPEGQFDHFLVQYRNGDG--QPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFH 2700
++SW E FD FLV + P+ + G + + + GL Y++ + GF
Sbjct: 1544 GFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT 1603
Query: 2701 GGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQ 2760
G + P+ VT AE E + L V+ ++PD LSWT +
Sbjct: 1604 QGHQTKPLRAEIVTEAEPE-------------------VDNLLVSDATPDGFRLSWTADE 1644
Query: 2761 GHFDSFTVQYKD--RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVST 2818
G FD+F ++ +D + P + + E + GL +Y++ LYG+ +GRR
Sbjct: 1645 GVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRR------ 1698
Query: 2819 VGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY-R 2877
++T A+ TT P E+ +D T +S ++SW P Q + F + Y
Sbjct: 1699 -------SQTVSAIATTAMGSPK-----EVIFSDITENSATVSWRAPTAQVESFRITYVP 1746
Query: 2878 NGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAP 2937
G P +V V G + + L P +Y +++ G + P+S TA + +
Sbjct: 1747 ITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSG-- 1804
Query: 2938 TEPSTEAPEPPEEPLLGELTVTGSSPDSLSLS-WTIPQGRFDSFTVQYKDRDGRPQVVR- 2995
VT + DS +L+ W DS+ + Y + P++ R
Sbjct: 1805 -------------------LVTANITDSEALARWQPAIATVDSYVISYTG-EKVPEITRT 1844
Query: 2996 VRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVT---APKDEAETTQAVPTMT 3052
V G E + LEP +Y + ++ Q+ ++A T +P+D
Sbjct: 1845 VSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD------------ 1892
Query: 3053 PEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVT 3112
LT T+ ++ L+W P +L+ Y + DG K V V +
Sbjct: 1893 -----------LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYS 1941
Query: 3113 ISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVT 3144
++ L P Y + +G R + I T
Sbjct: 1942 LADLSPSTHYTAKIQALNGPLRSNMIQTIFTT 1973
Score = 375 bits (964), Expect = e-103
Identities = 380/1582 (24%), Positives = 642/1582 (40%), Gaps = 266/1582 (16%)
Query: 1377 ELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGR-PRAVRVGGKESEVTVGGLEPGHK 1435
+L VT + ++++L W + V +G RV G ++ + LEPG +
Sbjct: 628 DLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVE 687
Query: 1436 YKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWT 1495
Y + ++ + E ++ PVSA T PA E L + SV + W
Sbjct: 688 YFIRVFAILENKKSIPVSARVAT------YLPAPEG--------LKFKSIKETSVEVEWD 733
Query: 1496 VPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVY---NLEPERKYKMNMYGLHDGQRMG 1552
+ F+++ + +++ + + + + +R T Y L P ++Y+++++ + + R
Sbjct: 734 PLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGP 793
Query: 1553 PLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY- 1611
L V T P+ ++ V D+T + ++W P E D + Y
Sbjct: 794 GLKRVTTTRLDAPS---------------QIEVKDVTDTTALITWFKPLAEIDGIELTYG 838
Query: 1612 -KDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDAS 1670
KD G + + D+ + +I +L+P +Y+ L + +P +T G +
Sbjct: 839 IKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK---ETFTTGLDA 895
Query: 1671 PGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHE-----RS 1725
P R+ + T +S+ L W + DS+ +++ G V+ +
Sbjct: 896 PRNLRRVSQ------TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTK 949
Query: 1726 VTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVT 1785
T+T L G +Y + + K P T + TE DT PK +LQV+
Sbjct: 950 TTLTGLRPGTEYGIGVSAVKEDKESNPATINAATEL-----DT-----PK-----DLQVS 994
Query: 1786 TVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLY 1845
+ S+ L W P +FD + + Y GQ V + + + GL+P Y +LL
Sbjct: 995 ETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLL- 1053
Query: 1846 GLHHGKRVGPISAVAITAGREETE-TETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVT 1904
GR +++ A T APE L LTV E L L+W
Sbjct: 1054 --------------TAEKGRHKSKPARVKASTEQAPE--LENLTVTEVGWDGLRLNWTAA 1097
Query: 1905 EGEFDSF--EIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVH 1962
+ ++ F ++Q ++ + + + G + + GL++ Y V++YG G +
Sbjct: 1098 DQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLS 1157
Query: 1963 VEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYR 2022
EA T P LGE+ V + D+L L+WT PEG +++F +Q +
Sbjct: 1158 AEASTGE-----------------TPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ 1200
Query: 2023 NGDGQPKA--VRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETP 2080
D A + VPG + GL+ Y +++ GVT TP
Sbjct: 1201 EADTVEAAQNLTVPGGLRSTDLPGLKAATHY--------------TITIRGVTQDFSTTP 1246
Query: 2081 SPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQV-- 2138
E E E P +G LTVT S D+L L+WT P G +D FT+Q ++ D +
Sbjct: 1247 LSVEVLTE-----EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHN 1301
Query: 2139 VRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLG 2198
+ V G + + GL G Y + L+G G P++ VT E+ P +LG
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT---EDLP-------QLG 1351
Query: 2199 QMTVRDITSDSLSLSWTVPEGQFDHFLVQFK--NGDGQPKAVRVPGHEDGVTISGLEPDH 2256
+ V ++ D L L+WT + ++HF++Q + N + + +PG V I GLE
Sbjct: 1352 DLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAAT 1411
Query: 2257 KYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATP 2316
Y++++YG G R +SA TA +P + L V+D TP
Sbjct: 1412 PYRVSIYGVIRGYRTPVLSAEASTAK--------------------EPEIGNLNVSDITP 1451
Query: 2317 DSLSLSWTVPEGQFDHFLVQYKNGDG--QPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
+S +LSW +G F+ F ++ + + + + G E ISGL P + + L G
Sbjct: 1452 ESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGL 1511
Query: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434
R +SA T A PLL LT++ +P ++SW
Sbjct: 1512 APSIRTKTISATATTEA-------------------LPLLENLTISDINPYGFTVSWMAS 1552
Query: 2435 QGRFDSFTVQYKDRDGR---PQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPV 2491
+ FDSF V D G+ PQ + G + ++ + GL G Y++ + G +G + P+
Sbjct: 1553 ENAFDSFLVTVVD-SGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPL 1611
Query: 2492 STVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2551
VT + +VD L V+ ++PD LSWT +G FD+
Sbjct: 1612 RAEIVTEAEPEVD----------------------NLLVSDATPDGFRLSWTADEGVFDN 1649
Query: 2552 FTVQYKD--RDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTE 2609
F ++ +D + P + + E + GL +Y++ LYG+ +GRR VSA+
Sbjct: 1650 FVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAI---- 1705
Query: 2610 DEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY-RNGDGQ 2668
A T P E+ +D T +S ++SW P Q + F + Y G
Sbjct: 1706 --ATTAMGSPK------------EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGT 1751
Query: 2669 PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELST 2728
P V V G + + L P +Y +++ G + P+S TA + P+ L
Sbjct: 1752 PSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD----GPSGL-- 1805
Query: 2729 EAPEPPEEPLLGELTVTGSSPDSLSLS-WTIPQGHFDSFTVQYKDRDGRPQVMR-VRGEE 2786
VT + DS +L+ W DS+ + Y + P++ R V G
Sbjct: 1806 ---------------VTANITDSEALARWQPAIATVDSYVISYTG-EKVPEITRTVSGNT 1849
Query: 2787 SEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLG 2846
E + LEP +Y + ++ GP ++ T A TT + P
Sbjct: 1850 VEYALTDLEPATEYTLRIFA-----EKGP--------QKSSTITAKFTTDLDSPR----- 1891
Query: 2847 ELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKY 2906
+LT T+ ++ L+W P +L+ Y + DG K V V +++ L P Y
Sbjct: 1892 DLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHY 1951
Query: 2907 KMNLYGFHGGQRVGPISVIGVT 2928
+ +G R I I T
Sbjct: 1952 TAKIQALNGPLRSNMIQTIFTT 1973
Score = 306 bits (785), Expect = 2e-82
Identities = 289/1183 (24%), Positives = 488/1183 (41%), Gaps = 193/1183 (16%)
Query: 762 ETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQR---GLAPGQEYQV 818
+ ++ EW +D+Y I++ P + G VP S A + GL PG EY +
Sbjct: 906 DNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVD--VPKSQQATTKTTLTGLRPGTEYGI 963
Query: 819 TVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAG 878
V A++ PA+ T +D P+DL+V T+L L W P A+ DR+ ++Y
Sbjct: 964 GVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPT 1023
Query: 879 NQRVRLEVPPEADGTLLTDLMPGVEY-------------------------------VVT 907
Q V +++P +L L PG EY VT
Sbjct: 1024 GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVT 1083
Query: 908 VTAERGRAVSYPAS----------------VRANTGSSPLGLLGTTDEP--PPSGPSTT- 948
G +++ A+ V A + G L D P + P T
Sbjct: 1084 EVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVS 1143
Query: 949 -----QGAQAPLLQQRPQ-----ELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVP 998
QG + P+L LGE+ V+ L++ WTA + YF ++++
Sbjct: 1144 IYGVIQGYRTPVLSAEASTGETPNLGEV-VVAEVGWDALKLNWTAPEGAYEYFFIQVQEA 1202
Query: 999 EGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPG 1057
+ A + + +PG +R +P T Y +++ GV + P+ + + ++
Sbjct: 1203 DTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTT-PLSVEVLTEE------ 1255
Query: 1058 KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQV--VPVEGPQRSA 1115
P +G LTVT+ + D+L L WT P+G +D F IQ ++ D + + V G RS
Sbjct: 1256 ----VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSM 1311
Query: 1116 VITSLDPGRKYKFVLYGFVGKKRHGPLVAEA--KILPQSDPSPGTPPHLGNLWVTDPTPD 1173
I L G Y L+G V PL E + LPQ LG+L V++ D
Sbjct: 1312 EIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQ----------LGDLAVSEVGWD 1361
Query: 1174 SLHLSWTVPEGQFDTFMVQYRD--RDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIA 1231
L L+WT + ++ F++Q ++ + Q + + G R+ + L+ YR +++G+
Sbjct: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
Query: 1232 NKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSF 1291
R L+A+ +TA E P +G L V+ +TP+S LSW G F++F
Sbjct: 1422 RGYRTPVLSAEASTAKE-------------PEIGNLNVSDITPESFNLSWMATDGIFETF 1468
Query: 1292 MVQYKDAQGQPQAVP--VAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAP 1349
++ D+ + V ++G E + GL P + + L GL R ++ TA
Sbjct: 1469 TIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRT---KTISATAT 1525
Query: 1350 QEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDR 1409
E + PLL LT++ +P ++ W + +FDSF V D
Sbjct: 1526 TEAL-------------------PLLENLTISDINPYGFTVSWMASENAFDSFLVTVVD- 1565
Query: 1410 DGR---PRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETP 1466
G+ P+ + G + ++ + GL G Y++ + G +G + P+ A VT
Sbjct: 1566 SGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA------ 1619
Query: 1467 PATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD--KDGQPQVVPVAADQ 1524
EP + L V+D TP+ LSWT EG FD+F+++ +D K +P + + A +
Sbjct: 1620 -------EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPE 1672
Query: 1525 REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELT 1584
R + L +Y++ +YG+ G+R +S + TA P E+
Sbjct: 1673 RTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPK---------------EVI 1717
Query: 1585 VTDITPDSVGLSWTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQREVTIPDLEPSRKYKF 1643
+DIT +S +SW P + +SF + Y G P +V V + + + L P +Y
Sbjct: 1718 FSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLV 1777
Query: 1644 LLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLS-WTVPEGQFD 1702
+ ++ + PVS T G + VT DS L+ W D
Sbjct: 1778 SIIAMKGFEESEPVSGSFTTALDGPSG----------LVTANITDSEALARWQPAIATVD 1827
Query: 1703 SFVVQFKDKDGPQVV-PVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEA 1761
S+V+ + + P++ V G+ +T L+ +Y ++ G ++ +TA TT+
Sbjct: 1828 SYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDL 1887
Query: 1762 RSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVP 1821
S D T T+ V + L+W P +++ Y+ DG + V
Sbjct: 1888 DSPRDLTATE---------------VQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI 1932
Query: 1822 VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAG 1864
V S+ L P+ Y + L+ R I + T G
Sbjct: 1933 VGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIG 1975
Score = 184 bits (466), Expect = 2e-45
Identities = 208/878 (23%), Positives = 330/878 (37%), Gaps = 161/878 (18%)
Query: 765 VRTEWTPAPGPVDAYEIQFIPTTEGASPPFTAR--VPSSASAYDQRGLAPGQEYQVTVRA 822
++ WT P AYE FI E + VP + D GL Y +T+R
Sbjct: 1181 LKLNWT---APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRG 1237
Query: 823 LRGTSWGLPAS-KTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGN-- 879
+ P S + +T + +L V V+ L L W P D+F + A
Sbjct: 1238 VTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVE 1297
Query: 880 QRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDE 939
+ L VP + L G Y VT+ E VR ++ + PL + T++
Sbjct: 1298 EAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGE----------VRGHS-TRPLAVEVVTED 1346
Query: 940 PPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMR-VP 998
P +LG+L V G LR+ WTA + + +F ++++ V
Sbjct: 1347 LP--------------------QLGDLAVSEVGWDG-LRLNWTAADNAYEHFVIQVQEVN 1385
Query: 999 EGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGK 1058
+ A LPG +R +P TPY +S++GV G + P++
Sbjct: 1386 KVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRT--PVL---------SAEAS 1434
Query: 1059 SSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVP--VEGPQRSAV 1116
++ P +G L V+D T +S L W +G F++F I+ D + + V + G +R+A
Sbjct: 1435 TAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAH 1494
Query: 1117 ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLH 1176
I+ L P + L G R + A A + P L NL ++D P
Sbjct: 1495 ISGLPPSTDFIVYLSGLAPSIRTKTISATA--------TTEALPLLENLTISDINPYGFT 1546
Query: 1177 LSWTVPEGQFDTFMVQYRDRDGR---PQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANK 1233
+SW E FD+F+V D G+ PQ + G +R + L Y + G
Sbjct: 1547 VSWMASENAFDSFLVTVVD-SGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQG 1605
Query: 1234 KRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMV 1293
+ PL A+ T E P + L V+ TPD RLSWT +G FD+F++
Sbjct: 1606 HQTKPLRAEIVTEAE-------------PEVDNLLVSDATPDGFRLSWTADEGVFDNFVL 1652
Query: 1294 QYKDA--QGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA--- 1348
+ +D Q +P + + E + GL +Y++ LYG+ +R S +A TA
Sbjct: 1653 KIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGS 1712
Query: 1349 PQE----------------------------------------DVDETPSPTELGTEAPE 1368
P+E VD T + T L P
Sbjct: 1713 PKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPG 1772
Query: 1369 -------------SPEEPLLGELT---------VTGSSPDSLSLF-WTVPQGSFDSFTVQ 1405
EP+ G T VT + DS +L W + DS+ +
Sbjct: 1773 VEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVIS 1832
Query: 1406 YKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEET 1465
Y V G E + LEP +Y + ++ GP + +TA +
Sbjct: 1833 YTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFA-----EKGPQKSSTITAKFTTDL 1887
Query: 1466 PPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQR 1525
PR +LT T+V + L+W P +++ Y+ DG + V V D
Sbjct: 1888 D-------SPR--DLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTT 1938
Query: 1526 EVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPL 1563
++ +L P Y + L+ R + + T L
Sbjct: 1939 SYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGL 1976
Score = 36.2 bits (82), Expect = 0.71
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 3934 PRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTP---GGQNQEILLPGGITSHQLLGLF 3990
P+DL EVT T L W + +R YL+ +TP GG + +PG TS + L
Sbjct: 626 PKDLVVTEVTEETVNLAW-DNEMRVTEYLV-VYTPTHEGGLEMQFRVPGDQTSTIIQELE 683
Query: 3991 PSTSYNARLQAMWGQSLLPPVSTSFTT 4017
P Y R+ A+ PVS T
Sbjct: 684 PGVEYFIRVFAILENKKSIPVSARVAT 710
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 532 bits (1371), Expect = e-150
Identities = 341/1096 (31%), Positives = 517/1096 (47%), Gaps = 75/1096 (6%)
Query: 3154 PSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR--DGQPQVVRVR 3211
P A PE+ L V G S S+ L W P + + Y+ G RV
Sbjct: 321 PDCSAVAPPED-----LRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVP 374
Query: 3212 GEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAV 3271
G+ S VT+ LEPG Y + +Y + + + ++ ITA + T L L +
Sbjct: 375 GDWSGVTITELEPGLTYNISVYAV-----ISNILSLPITAKVATHLSTPQGL---QFKTI 426
Query: 3272 TSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVP-VSGDLRAVAVSGLDPARKYKFLLFG 3330
T +V + W FD + + + + + V D+ + +GL P +Y +
Sbjct: 427 TETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVA 486
Query: 3331 LQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYK-- 3388
L+ R P T D ++ V D + + W P + D +++Y
Sbjct: 487 LKEQARSPPTSASVSTVIDGPT-----QILVRDVSDTVAFVEWIPPRAKVDFILLKYGLV 541
Query: 3389 DKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPP 3448
+G + + +VQ L P +Y + + G + TT E + P
Sbjct: 542 GGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPK 598
Query: 3449 HLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPR---AVPVAADQRT-VTVED 3504
+L V T++SL L W ++ + V Y G+ VP T T+ D
Sbjct: 599 NL---RVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTD 655
Query: 3505 LEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTD 3564
L PG +Y + ++ ++ P + T E D+P L VT
Sbjct: 656 LVPGTEYGVGISAVMNSQQSVPATMNART--ELDSPRD-----------------LMVTA 696
Query: 3565 TTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYG 3624
++ S+ L W+ A GP D + + + ++G + V D++ ++ LEP Y +
Sbjct: 697 SSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA 756
Query: 3625 LHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL 3684
++ + + TG P +S L + VT+SS+ + W P D +
Sbjct: 757 ERGRQQSLESTVDAFTGFRP-----------ISHLHFSHVTSSSVNITWSDPSPPADRLI 805
Query: 3685 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 3744
L + P E+ + T+ AVL L+ T Y + L + G ++ I
Sbjct: 806 LNYS--------PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIV 857
Query: 3745 GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQ 3804
G+ T ++ P+D+ S + + S V+W PP + D ++VSY+ G S V
Sbjct: 858 GSITT---GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNT 914
Query: 3805 ARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWK 3864
+ L P YE+++ SVRG EESE + + T D P L A N+T A+L WK
Sbjct: 915 VTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWK 974
Query: 3865 PPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS 3924
P V+ Y + +T G + ++ L DL+ T+YTAT+ GP + S
Sbjct: 975 APVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTIS 1034
Query: 3925 ITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSH 3984
F+T L+ P +L A EVT ++AL++W P Y+L++ + G +E+++ T
Sbjct: 1035 TNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWI 1094
Query: 3985 QLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTI 4044
+L GL +T Y LQA + ST+FTTGG P P+DC + + NG S I
Sbjct: 1095 RLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPI 1154
Query: 4045 FLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEA 4104
FLNG + L V+CDM TDGGGW+VFQRR +GQTDF+R W DY GFGN+ EFWLG +
Sbjct: 1155 FLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDN 1214
Query: 4105 LHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGS 4164
+H +T G Y +RVD+R G EA FA YD F V+ + Y+L + Y+GTAGDS+SYH G
Sbjct: 1215 IHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGR 1274
Query: 4165 VFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVP 4224
FS DRD + + +CA+SY+GAWWY+NCH NLNG YG + QG++WYHWKG EFS+P
Sbjct: 1275 PFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIP 1334
Query: 4225 FTEMKLRPRNFRSPAG 4240
F EMK+RP N R AG
Sbjct: 1335 FVEMKMRPYNHRLMAG 1350
Score = 366 bits (940), Expect = e-100
Identities = 284/1048 (27%), Positives = 432/1048 (41%), Gaps = 140/1048 (13%)
Query: 532 CRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQ 589
C GHG E C+C+ G+ G++CS CP GC RG C+DG+C+C+ YSG+DC +
Sbjct: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
Query: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649
CP DCS G+C DG C+C E Y EDC CP +C G+GRC G CLC+ GY G C
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
Query: 650 RMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPR--ELCRAGQCVCVE 707
R C C GRG+C +G+C+C GY G DC PP G R EL G E
Sbjct: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTE 354
Query: 708 -------GFRGPDCAIQTCPGDCRG--RGECHDGSCVCKDGYA----------GEDCGEE 748
G Q PGD G E G YA
Sbjct: 355 YVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATH 414
Query: 749 VPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIP-TTEGASPPFTARVPSSASAYDQ 807
+ T +G++ + ETTV +W P D +EI FIP EG A+VPS ++++Q
Sbjct: 415 LSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGG---VIAQVPSDVTSFNQ 471
Query: 808 RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEV 867
GL PG+EY V V AL+ + P S +++T+IDGP + V V+ T + W+ P+A+V
Sbjct: 472 TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKV 531
Query: 868 DRFVVSYVSAGNQ--RVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
D ++ Y G + R + P + L PG Y V+V+A RG
Sbjct: 532 DFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRG------------ 579
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
T+E + T AP LRV R T L + W
Sbjct: 580 -----------TNESDSATTQFTTEIDAP---------KNLRVGSRTATS-LDLEWDNSE 618
Query: 986 DTFAYFQLRMRVPEGPGAHEEVLP---GDVRQALVPPPPPGTPYELSLHGVPPGGKPSDP 1042
+++ G HE ++P G +A + PGT Y + + V + S P
Sbjct: 619 AEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAV-MNSQQSVP 677
Query: 1043 IIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102
+ D + +L VT + S+ L WT G D + I + G
Sbjct: 678 ATMNARTELDSPR-----------DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGI 726
Query: 1103 PQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHL 1162
V V + S +T L+PG +Y + G+++ + D G P +
Sbjct: 727 ASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQ--------SLESTVDAFTGFRP-I 777
Query: 1163 GNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV--VPVEGPERSFVVSSLDPD 1220
+L + T S++++W+ P D ++ Y RD ++ V ++ +R V+ L P
Sbjct: 778 SHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPA 837
Query: 1221 HKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLS 1280
+Y L + P+ TT +PP+ ++T++ VT DS+ +S
Sbjct: 838 TEYIVNLVAVHGTVTSEPIVGSITTG----IDPPK----------DITISNVTKDSVMVS 883
Query: 1281 WTVAQGPFDSFMVQYKDAQ-GQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVG 1339
W+ FD + V Y+ Q G+ + V E T+ L+P +Y+++L +RGR+
Sbjct: 884 WSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESE 943
Query: 1340 PESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSF 1399
+ TA VD L T +P L W P G
Sbjct: 944 RICTLVHTAMDNPVD-----------------------LIATNITPTEALLQWKAPVGEV 980
Query: 1400 DSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTA 1459
+++ + + V G E + L P Y +Y + G +S T
Sbjct: 981 ENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL 1040
Query: 1460 PQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVP 1519
PPA LT ++VT S +SW P + +++++ YK DG + +
Sbjct: 1041 LD----PPA----------NLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELI 1086
Query: 1520 VAADQREVTVYNLEPERKYKMNMYGLHD 1547
V A+ + + L Y + + D
Sbjct: 1087 VDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
Score = 345 bits (886), Expect = 4e-94
Identities = 290/1116 (25%), Positives = 453/1116 (40%), Gaps = 152/1116 (13%)
Query: 566 RGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG--VCQDGVCICWEGYVSEDCSIRTCPS 623
R QC + C E +G+ + P+ CS HG + CIC EG+ ++CS CP
Sbjct: 152 RDQC-NANCCQESAATGQ---LDYIPH-CSGHGNFSFESCGCICNEGWFGKNCSEPYCPL 206
Query: 624 NCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEP 683
C RG C +G+C+CD Y+G C+ CP DC RG CV G C+C Y GEDC +
Sbjct: 207 GCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELR- 265
Query: 684 PASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGE 743
CPG C + C G C+C EG+ G DC + C C GRG+C +G CVC++GY G
Sbjct: 266 ----CPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGP 321
Query: 744 DCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSAS 803
DC P E +R+ + + ++ EW P V Y I + PT G RVP S
Sbjct: 322 DCSAVAPP-EDLRVAGISDRSIELEWD-GPMAVTEYVISYQPTALGGLQ-LQQRVPGDWS 378
Query: 804 AYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRP 863
L PG Y ++V A+ LP + + T + PQ L+ +T TT+E+ W
Sbjct: 379 GVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF 438
Query: 864 QAEVDRFVVSYVSAGNQR-VRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASV 922
D + +S++ N+ V +VP + T L PG EY+V V A + +A S P S
Sbjct: 439 SFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
Query: 923 RANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVV-W 981
+T G ++L RD + + V W
Sbjct: 499 SVSTVID----------------------------------GPTQILVRDVSDTVAFVEW 524
Query: 982 TAQPDTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPS 1040
+ L+ + G G L + Q V PG+ YE+S+ V G S
Sbjct: 525 IPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVR-GTNES 583
Query: 1041 DPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRD 1100
D Q + D K L V RT+ SL L W E E + + Y
Sbjct: 584 DSATTQFTTEIDAPK-----------NLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLA 632
Query: 1101 GQPQ---VVPVE-GPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSP 1156
G+ +VP GP A +T L PG +Y + + ++ P A+ S
Sbjct: 633 GEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPR-- 690
Query: 1157 GTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSS 1216
+L VT + S+ L WT G D + + + G V V S+ ++
Sbjct: 691 -------DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTD 743
Query: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
L+P +Y ++ +++ T D T RP + L + VT S
Sbjct: 744 LEPGAEYIISVTAERGRQQSLESTVDAFTGF-------RP-------ISHLHFSHVTSSS 789
Query: 1277 LRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRG 1334
+ ++W+ P D ++ Y +D + + V + + + GL P +Y +NL + G
Sbjct: 790 VNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHG 849
Query: 1335 RQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTV 1394
V E +V G + P+ ++T++ + DS+ + W+
Sbjct: 850 T--VTSEPIVGSITT-------------GIDPPK--------DITISNVTKDSVMVSWSP 886
Query: 1395 PQGSFDSFTVQYKDRD-GRPRAVRVGGKESEVTVGGLEPGHKYKMHLY---GLHEGQRVG 1450
P SFD + V Y+ GR + V +E T+ L P +Y++ L G E +R+
Sbjct: 887 PVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERIC 946
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510
+ A ++P++ L T++TP L W P G+ +++++
Sbjct: 947 TL------------VHTAMDNPVD-----LIATNITPTEALLQWKAPVGEVENYVIVLTH 989
Query: 1511 KDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATE 1570
+ + V E + +L P Y MY + G +S T PPA
Sbjct: 990 FAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLLDPPA---- 1045
Query: 1571 ASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREV 1630
LT +++T S +SW P E +++V+ YK DG + + V A+ +
Sbjct: 1046 -----------NLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWI 1094
Query: 1631 TIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVAR 1666
+ L + Y LL QD S S T R
Sbjct: 1095 RLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGR 1130
Score = 221 bits (563), Expect = 1e-56
Identities = 107/245 (43%), Positives = 127/245 (51%), Gaps = 24/245 (9%)
Query: 68 EKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCP 127
E QV FTHRIN P CP + VL Q L R+E+LE V L++QC CC
Sbjct: 109 ESQVTFTHRINFPKKA---CPCASSAQVL----QELLSRIEMLEREVSVLRDQCNANCCQ 161
Query: 128 ASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSC 187
SA TGQ D CS HG F C C C GW G CS+P C
Sbjct: 162 ESA--ATGQLDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPY---------------C 204
Query: 188 PDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQR 247
P C+ +G CV G+C+C Y+G C CP DC RG CV G CVC ++G DC +
Sbjct: 205 PLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCREL 264
Query: 248 SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
CP CS +GRC G C+C+ GY G+DCG R C CS RG+CE G CVC GY G DC
Sbjct: 265 RCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCS 324
Query: 308 VRSCP 312
+ P
Sbjct: 325 AVAPP 329
Score = 197 bits (501), Expect = 2e-49
Identities = 83/168 (49%), Positives = 103/168 (61%), Gaps = 2/168 (1%)
Query: 284 CSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRS 341
CS G E+ C+CN G+ G++C CP GCS RG C DG+C+CD Y+G+DC
Sbjct: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
Query: 342 CPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGV 401
CP DC G CVDG CVC YTGEDC CP DC G+GRC +G C+C+ GY G+DCG
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
Query: 402 RSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGV 449
R C C+ RG+CE+G CVC GY G DC + A P D R G + +
Sbjct: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSI 342
Score = 194 bits (493), Expect = 2e-48
Identities = 82/174 (47%), Positives = 100/174 (57%), Gaps = 2/174 (1%)
Query: 439 CRGRGRC--ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRA 496
C G G E+ C+CN G+ G++C CP C RG C G+C+C Y+G DC
Sbjct: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
Query: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
CP DC RG CVDG CVC +TGEDC RCPGDC G G C +G C+C+ GY GEDC
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
Query: 557 RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEG 610
R C C GRGQC +G CVCE+GY G DC P D G+ + + W+G
Sbjct: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDG 348
Score = 192 bits (489), Expect = 5e-48
Identities = 81/149 (54%), Positives = 92/149 (61%)
Query: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
C+C G+ G++CS CP C RG C DG+CICD+ YSGDDC CP DC+ RG C D
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476
G CVC YTG DC CP DC G+GRC NG C+C GY GEDCG R C C GRG+C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 477 ESGRCMCWPGYTGRDCGTRACPGDCRGRG 505
E G C+C GY G DC A P D R G
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
Score = 192 bits (487), Expect = 8e-48
Identities = 84/188 (44%), Positives = 111/188 (59%), Gaps = 3/188 (1%)
Query: 442 RGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
R +C N C + +G+ + C G G ES C+C G+ G++C CP C
Sbjct: 152 RDQC-NANCCQESAATGQLDYIPHCSG--HGNFSFESCGCICNEGWFGKNCSEPYCPLGC 208
Query: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPG 561
RG CVDG+C+C+ ++G+DC RCP DC GLC DG CVC+ Y+GEDC CPG
Sbjct: 209 SSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPG 268
Query: 562 GCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTC 621
C G+G+C +G C+CE+GY GEDCG RQC N CS G C++G+C+C EGY DCS
Sbjct: 269 DCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAP 328
Query: 622 PSNCHGRG 629
P + G
Sbjct: 329 PEDLRVAG 336
Score = 189 bits (481), Expect = 4e-47
Identities = 76/161 (47%), Positives = 98/161 (60%)
Query: 326 CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCED 385
C+C+ G+ G++C CP C G CVDG+C+C Y+G+DCS CP DC RG C D
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 386 GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
GEC+C+ Y+G+DC CPGDC+ +GRC +G C+C GY G DCG R C C GRG+C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPG 486
E G+CVC GY G DC + P D R G + + W G
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDG 348
Score = 186 bits (473), Expect = 3e-46
Identities = 83/191 (43%), Positives = 104/191 (54%), Gaps = 9/191 (4%)
Query: 243 DCSQRSCPRG-------CSQRGRC--EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENG 293
+C Q S G CS G E C+C+ G+ G +C CP GCS RG C +G
Sbjct: 158 NCCQESAATGQLDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDG 217
Query: 294 RCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCV 353
+C+C+ Y+G+DC CP CS RG C DG CVC+ YTGEDC CP DC GRC
Sbjct: 218 QCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 277
Query: 354 DGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGR 413
+G C+C GY GEDC R C C GRG+CE+G C+C+ GY G DC + P D G
Sbjct: 278 NGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGI 337
Query: 414 CEDGRCVCWPG 424
+ + W G
Sbjct: 338 SDRSIELEWDG 348
Score = 186 bits (472), Expect = 4e-46
Identities = 211/900 (23%), Positives = 359/900 (39%), Gaps = 138/900 (15%)
Query: 2633 ELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV-------RVPGHEDGVTISG 2685
+L + + S+ L W P + +++ Y QP A+ RVPG GVTI+
Sbjct: 331 DLRVAGISDRSIELEWDGPMAVTE-YVISY-----QPTALGGLQLQQRVPGDWSGVTITE 384
Query: 2686 LEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVT 2745
LEP Y +++Y + I + +TA T LST P+ + + E TV
Sbjct: 385 LEPGLTYNISVYAV-----ISNILSLPITAKVA-----THLST--PQGLQFKTITETTV- 431
Query: 2746 GSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVM-RVRGEESEVTVGGLEPGRKYKMHL 2804
+ W FD + + + ++ V+ +V + + GL+PG +Y +++
Sbjct: 432 -------EVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNV 484
Query: 2805 YGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMV 2864
L E R P T+ +V T P ++ V D + + W+
Sbjct: 485 VALKEQARSPP------------TSASVSTVIDGPT------QILVRDVSDTVAFVEWIP 526
Query: 2865 PEGQFDHFLVQYR--NGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPI 2922
P + D L++Y G+G R+ ++ L P +Y+ +
Sbjct: 527 PRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYE--------------V 572
Query: 2923 SVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTV 2982
SV V E A T+ +TE + P+ +G T T SL L W + + V
Sbjct: 573 SVSAVRGTNESDSATTQFTTEI-DAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKV 626
Query: 2983 QYKDRDGRPQ----VVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAP 3038
Y G V R G + T+ L PG +Y VG++A
Sbjct: 627 VYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEY-----------------GVGISAV 669
Query: 3039 KDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQ 3098
+ ++ A E PR +L VT ++ S+SL W G DH+ + + G
Sbjct: 670 MNSQQSVPATMNARTELD-SPR--DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGI 726
Query: 3099 PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEA 3158
V VP T++ LEP +Y I VT E + ST
Sbjct: 727 ASEVTVPKDRTSYTLTDLEPGAEY-----------------IISVTAERGRQQSLESTVD 769
Query: 3159 PEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVR--GEESE 3216
P + L + + S++++W+ P D + Y RD + +++ V +
Sbjct: 770 AFTGFRP-ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRH 828
Query: 3217 VTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSV 3276
+ GL+P +Y ++L +H G V++ I + T + P+ ++ ++ VT DSV
Sbjct: 829 AVLMGLQPATEYIVNLVAVH-----GTVTSEPIVGSITTGID-PPK--DITISNVTKDSV 880
Query: 3277 GLSWTVAQGPFDSFLVQYRDAQ-GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGK 3335
+SW+ FD + V YR Q G+ + V + ++ L+PA +Y+ L ++ +
Sbjct: 881 MVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGRE 940
Query: 3336 RHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQ 3395
+ TA D +L T+ TP L W P GE +++V+ +
Sbjct: 941 ESERICTLVHTAMDNPV-----DLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE 995
Query: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455
+ V E + L PS Y +Y +G G IS + +T L+ PP LT
Sbjct: 996 TILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL-LD---PP--ANLTA 1049
Query: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLL 3515
+E T S +SW + +++V+ Y+ TDG + + V A+ + +E L Y LL
Sbjct: 1050 SEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLL 1109
Score = 182 bits (462), Expect = 6e-45
Identities = 80/188 (42%), Positives = 104/188 (55%), Gaps = 3/188 (1%)
Query: 380 RGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDC 439
R +C + C ++ +G + C G N E C+C G+ G +C CP C
Sbjct: 152 RDQC-NANCCQESAATGQLDYIPHCSGHGNFS--FESCGCICNEGWFGKNCSEPYCPLGC 208
Query: 440 RGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPG 499
RG C +G C+C++ YSG+DC CP DC RG C G C+C YTG DC CPG
Sbjct: 209 SSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPG 268
Query: 500 DCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC 559
DC G+GRC +G C+C G+ GEDCG R+C C G G CE+G+CVC+ GY G DCS +
Sbjct: 269 DCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAP 328
Query: 560 PGGCRGRG 567
P R G
Sbjct: 329 PEDLRVAG 336
Score = 182 bits (462), Expect = 6e-45
Identities = 76/149 (51%), Positives = 90/149 (60%)
Query: 233 CVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCEN 292
C+C G+ G +CS+ CP GCS RG C G+C+CD Y+GDDC CP CS RG C +
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 293 GRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
G CVC YTGEDC CP CS +GRC +G C+C+ GY GEDCG R C C G+C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 353 VDGRCVCWPGYTGEDCSTRTCPRDCRGRG 381
+G CVC GY G DCS P D R G
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
Score = 181 bits (460), Expect = 1e-44
Identities = 77/168 (45%), Positives = 96/168 (57%), Gaps = 2/168 (1%)
Query: 377 CRGRGRC--EDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRA 434
C G G E CIC+ G+ G +C CP C+ RG C DG+C+C Y+G DC
Sbjct: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
Query: 435 CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494
CP DC RG C +G CVC Y+GEDC CPGDC G+GRC +G C+C GY G DCG
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
Query: 495 RACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGV 542
R C C GRG+C +G CVC G+ G DC + P D R G+ + +
Sbjct: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSI 342
Score = 159 bits (401), Expect = 7e-38
Identities = 200/939 (21%), Positives = 353/939 (37%), Gaps = 173/939 (18%)
Query: 2200 MTVRDITSDSLSLSWTVPEGQFDHFLVQFKNG-DGQPKAVRVPGHEDGVTISGLEPDHKY 2258
+ V I+ S+ L W P ++ + G RVPG GVTI+ LEP Y
Sbjct: 332 LRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY 391
Query: 2259 KMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDS 2318
+++Y + + ++ +TA +T TP+ L+ T+T+ T
Sbjct: 392 NISVYAV-----ISNILSLPITAK--------VATHLSTPQG-----LQFKTITETT--- 430
Query: 2319 LSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHG 2376
+ + W FD + + + KN +G A +VP +GL+P +Y +N+
Sbjct: 431 VEVQWEPFSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKE 489
Query: 2377 GQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQG 2436
R P SA T + T ++ V S + W P+
Sbjct: 490 QARSPPTSASVSTVIDGPT--------------------QILVRDVSDTVAFVEWIPPRA 529
Query: 2437 RFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2494
+ D ++Y +G R+ S+ +V L PG +Y++ VS V
Sbjct: 530 KVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVS------------VSAV 577
Query: 2495 GVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 2554
T +E+ S T T P+ +G T T SL L W + + V
Sbjct: 578 RGT------NESDSATTQFTTEIDAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKV 626
Query: 2555 QYKDRDGRPQ----AVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTED 2610
Y G R G ++ T+ L PG +Y + + + ++ P + TE
Sbjct: 627 VYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTEL 686
Query: 2611 EAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPK 2670
++ PR +L +T ++ S+SL WT G DH+ + + G
Sbjct: 687 DS----------------PR--DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIAS 728
Query: 2671 AVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEA 2730
V VP T++ LEP +Y +++ G Q+ +V T
Sbjct: 729 EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP------------ 776
Query: 2731 PEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVR--GEESE 2788
+ L + + S++++W+ P D + Y RD ++M V +
Sbjct: 777 --------ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRH 828
Query: 2789 VTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGEL 2848
+ GL+P +Y ++L +H G V+ +E TT +PP ++
Sbjct: 829 AVLMGLQPATEYIVNLVAVH-----GTVT--------SEPIVGSITTGIDPPK-----DI 870
Query: 2849 TVTDATPDSLSLSWMVPEGQFDHFLVQYRNGD-GQPKVVRVPGHEDGVTISGLEPDHKYK 2907
T+++ T DS+ +SW P FD++ V YR G+ VP TI+ L P +Y+
Sbjct: 871 TISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYE 930
Query: 2908 MNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLS 2967
++L G + I + TA + +L T +P
Sbjct: 931 ISLNSVRGREESERICTLVHTAMDNPV--------------------DLIATNITPTEAL 970
Query: 2968 LSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRV 3027
L W P G +++ + + + V G E + L P Y +Y +
Sbjct: 971 LQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATN----- 1025
Query: 3028 GPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDH 3087
GP++ + T + +PP LT ++ T S +SW P + ++
Sbjct: 1026 GPLT----------SGTISTNFSTLLDPP-----ANLTASEVTRQSALISWQPPRAEIEN 1070
Query: 3088 FLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 3126
+++ Y++ DG K + V + + + GL + Y + L
Sbjct: 1071 YVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLL 1109
Score = 157 bits (397), Expect = 2e-37
Identities = 197/936 (21%), Positives = 343/936 (36%), Gaps = 161/936 (17%)
Query: 1668 DASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDK--DGPQVVP-VEGHER 1724
D S APP +L V + S+ L W P + +V+ ++ G Q+ V G
Sbjct: 322 DCSAVAPPE--DLRVAGISDRSIELEWDGPMAVTE-YVISYQPTALGGLQLQQRVPGDWS 378
Query: 1725 SVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQV 1784
VT+T L+ G Y +Y ++ P+TA T + + LQ
Sbjct: 379 GVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTP---------------QGLQF 423
Query: 1785 TTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVP-VEGSLREVSVPGLDPAHRYKLL 1843
T+T+ +V + W FD + + + ++ + V+ V + + GL P Y +
Sbjct: 424 KTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVN 483
Query: 1844 LYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMV 1903
+ L R P SA T PT ++ V + + + W+
Sbjct: 484 VVALKEQARSPPTSA--------SVSTVIDGPT---------QILVRDVSDTVAFVEWIP 526
Query: 1904 TEGEFDSFEIQY--TDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPV 1961
+ D ++Y +G R+ + ++ L RY V++
Sbjct: 527 PRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTN----- 581
Query: 1962 HVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY 2021
E + + T + P R+G T T SL L W E + + V Y
Sbjct: 582 --------ESDSATTQFTTEIDAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKVVY 628
Query: 2022 RNGDG-QPKAVRVP---GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEE 2077
G Q V VP G T++ L P +Y + + Q+ P ++ A
Sbjct: 629 STLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATM----NART 684
Query: 2078 ETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQ 2137
E SP + L VT SS S+SL WT G D + + + G
Sbjct: 685 ELDSPRD----------------LMVTASSETSISLIWTKASGPIDHYRITFTPSSGIAS 728
Query: 2138 VVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRL 2197
V V + + T+ LEPG +Y + + GR+ S V DA +
Sbjct: 729 EVTVPKDRTSYTLTDLEPGAEYIISVTA-ERGRQQSLESTV----------DAFTGFRPI 777
Query: 2198 GQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVP--GHEDGVTISGLEPD 2255
+ +TS S++++W+ P D ++ + D + + + V + + GL+P
Sbjct: 778 SHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPA 837
Query: 2256 HKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDAT 2315
+Y +NL HG P+ VG G D PP +++T+++ T
Sbjct: 838 TEYIVNLVAVHGTVTSEPI--VGSITTGID--------------PP-----KDITISNVT 876
Query: 2316 PDSLSLSWTVPEGQFDHFLVQYKNGD-GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
DS+ +SW+ P FD++ V Y+ G+ ++ VP TI+ L P +Y+++L
Sbjct: 877 KDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSV 936
Query: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434
G + + + TA + +L T +P L W P
Sbjct: 937 RGREESERICTLVHTAMDNPV--------------------DLIATNITPTEALLQWKAP 976
Query: 2435 QGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2494
G +++ + + + V G E + L P Y +Y + G +ST
Sbjct: 977 VGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTN 1036
Query: 2495 GVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 2554
T PP LT + + S +SW P+ +++ +
Sbjct: 1037 FSTLLD------------------PP-----ANLTASEVTRQSALISWQPPRAEIENYVL 1073
Query: 2555 QYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHL 2590
YK DG + + V +++ + + GL Y + L
Sbjct: 1074 TYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLL 1109
Score = 157 bits (396), Expect = 3e-37
Identities = 193/926 (20%), Positives = 348/926 (37%), Gaps = 150/926 (16%)
Query: 1567 PATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVA 1624
P A PP +L V I+ S+ L W P + +V+ Y+ G V
Sbjct: 321 PDCSAVAPP-----EDLRVAGISDRSIELEWDGPMAVTE-YVISYQPTALGGLQLQQRVP 374
Query: 1625 ADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTD 1684
D VTI +LEP Y ++ + P++ + T P L +T+
Sbjct: 375 GDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHL------STPQGLQFKTITE 428
Query: 1685 PTPDSLRLSWTVPEGQFDSFVVQF--KDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLY 1742
T + + W FD + + F K+ +G + V S T L G +Y +
Sbjct: 429 TT---VEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVV 485
Query: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
L + R P +A +T + D T ++ V V+ + W P +
Sbjct: 486 ALKEQARSPPTSASVST-----VIDGPT----------QILVRDVSDTVAFVEWIPPRAK 530
Query: 1803 FDSFVVQYK--DRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
D +++Y +G ++ L + SV L P RY++ +V+
Sbjct: 531 VDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEV---------------SVS 575
Query: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920
G E+++ TT T P L V T+ +L L W +E E +++ Y+ G
Sbjct: 576 AVRGTNESDSATTQFTTEIDAPK--NLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAG 633
Query: 1921 Q----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976
+ + + R G TL+ L Y V + + + P + A T E + P +
Sbjct: 634 EQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNART--ELDSPRD 691
Query: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGH 2036
L VT ++ S+SL WT G DH+ + + G V VP
Sbjct: 692 ----------------LMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKD 735
Query: 2037 EEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEP 2096
T++ LEP +Y +++ G Q+ +V T
Sbjct: 736 RTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP------------------- 776
Query: 2097 LLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVG--GEESEVTVGGLE 2154
+ L + + S++++W+ P D + Y RD +++ V + + GL+
Sbjct: 777 -ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQ 835
Query: 2155 PGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSW 2214
P +Y ++L +H G V++ + D P +T+ ++T DS+ +SW
Sbjct: 836 PATEYIVNLVAVH-----GTVTSEPIVGSITTGIDPP------KDITISNVTKDSVMVSW 884
Query: 2215 TVPEGQFDHFLVQFKNGD-GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGP 2273
+ P FD++ V ++ G+ + VP TI+ L P +Y+++L G +
Sbjct: 885 SPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESER 944
Query: 2274 VSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHF 2333
+ + TA + P+ +L T+ TP L W P G+ +++
Sbjct: 945 ICTLVHTA----------------MDNPV-----DLIATNITPTEALLQWKAPVGEVENY 983
Query: 2334 LVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEE 2393
++ + + V G + + L P Y +Y +G G +S T
Sbjct: 984 VIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL-- 1041
Query: 2394 ETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQ 2453
+PP LT + + S +SW P+ +++ + YK DG +
Sbjct: 1042 -------------DPP-----ANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRK 1083
Query: 2454 VVRVGGEESEVTVGGLEPGRKYKMHL 2479
+ V E++ + + GL Y + L
Sbjct: 1084 ELIVDAEDTWIRLEGLLENTDYTVLL 1109
Score = 153 bits (387), Expect = 3e-36
Identities = 194/898 (21%), Positives = 328/898 (36%), Gaps = 143/898 (15%)
Query: 984 QPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPI 1043
QP QL+ RVP GD + PG Y +S++ V I
Sbjct: 360 QPTALGGLQLQQRVP-----------GDWSGVTITELEPGLTYNISVYAVISN------I 402
Query: 1044 IYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQP 1103
+ I K S P L T+T+ T + ++W FD + I + ++ +
Sbjct: 403 LSLPITAKVATH---LSTPQGLQFKTITETTVE---VQWEPFSFSFDGWEISFIPKNNEG 456
Query: 1104 QVVP-VEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHL 1162
V+ V S T L PG +Y + + R P A +
Sbjct: 457 GVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQ------- 509
Query: 1163 GNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR--DRDGRPQVVPVEGPERSFVVSSLDPD 1220
+ V D + + W P + D +++Y +G ++ P + V +L P
Sbjct: 510 --ILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPG 567
Query: 1221 HKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLS 1280
+Y ++ + T TT + + L V T SL L
Sbjct: 568 SRYEVSVSAVRGTNESDSATTQFTTEIDAPKN--------------LRVGSRTATSLDLE 613
Query: 1281 WTVAQGPFDSFMVQYKDAQGQPQ---AVPVA-GDENEVTVPGLDPDRKYKMNLYGLRGRQ 1336
W ++ + V Y G+ VP G T+ L P +Y + + + Q
Sbjct: 614 WDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQ 673
Query: 1337 RVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQ 1396
+ P ++ A+T E SP +L VT SS S+SL WT
Sbjct: 674 QSVPATMNART-------ELDSPRDL----------------MVTASSETSISLIWTKAS 710
Query: 1397 GSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVG 1456
G D + + + G V V + T+ LEPG +Y +
Sbjct: 711 GPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEY-----------------IIS 753
Query: 1457 VTAPQQEETPPATESPLEPRLG-----ELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDK 1511
VTA + + + ES ++ G L + VT +SV ++W+ P D I+ Y +
Sbjct: 754 VTAERGRQQ--SLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPR 811
Query: 1512 DGQPQVVPVAAD--QREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPAT 1569
D + +++ V+ D +R + L+P +Y +N+ +H P+ I T PP
Sbjct: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPK--- 868
Query: 1570 EASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRD-GQPQVVPVAADQR 1628
++T++++T DSV +SW+ P FD + V Y+ G+ V
Sbjct: 869 ------------DITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVT 916
Query: 1629 EVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPD 1688
E TI L P+ +Y+ L ++ + + T +L T+ TP
Sbjct: 917 EFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPV---------DLIATNITPT 967
Query: 1689 SLRLSWTVPEGQFDSFVVQFKD-KDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGK 1747
L W P G+ +++V+ + + V+G + L Y +Y
Sbjct: 968 EALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYAT--- 1024
Query: 1748 KRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFV 1807
+GPLT+ + S + D PP L + VT+ S +SW P + +++V
Sbjct: 1025 --NGPLTSGTISTNFSTLLD-----PPA-----NLTASEVTRQSALISWQPPRAEIENYV 1072
Query: 1808 VQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGR 1865
+ YK DG + + V+ + + GL Y +LL S T GR
Sbjct: 1073 LTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGR 1130
Score = 148 bits (373), Expect = 1e-34
Identities = 189/912 (20%), Positives = 346/912 (37%), Gaps = 144/912 (15%)
Query: 1062 PPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDR--DGQPQVVPVEGPQRSAVITS 1119
PP +L V + S+ L W P + +VI Y+ G V G IT
Sbjct: 328 PPE--DLRVAGISDRSIELEWDGPMAVTE-YVISYQPTALGGLQLQQRVPGDWSGVTITE 384
Query: 1120 LDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSW 1179
L+PG Y +Y + P+ A+ TP L +T+ T + + W
Sbjct: 385 LEPGLTYNISVYAVISNILSLPITAKVAT------HLSTPQGLQFKTITETT---VEVQW 435
Query: 1180 TVPEGQFDTFMVQYRDRDGRPQVVP-VEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGP 1238
FD + + + ++ V+ V SF + L P +Y + + + R P
Sbjct: 436 EPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPP 495
Query: 1239 LTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYK-- 1296
+A +T ++ P ++ V V+ + W + D +++Y
Sbjct: 496 TSASVSTV------------IDGPT--QILVRDVSDTVAFVEWIPPRAKVDFILLKYGLV 541
Query: 1297 DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDET 1356
+G + ++ +V L P +Y++++ +RG +E+
Sbjct: 542 GGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRG------------------TNES 583
Query: 1357 PSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGR---- 1412
S T T ++P+ +G T T SL L W + + V Y G
Sbjct: 584 DSATTQFTTEIDAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKVVYSTLAGEQYHE 638
Query: 1413 ---PRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPAT 1469
PR + G + T+ L PG +Y + + + Q+ P + + A + ++P
Sbjct: 639 VLVPRGI---GPTTRATLTDLVPGTEYGVGISAVMNSQQSVPAT---MNARTELDSPR-- 690
Query: 1470 ESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTV 1529
+L VT + S+ L WT G D + + + G V V D+ T+
Sbjct: 691 ---------DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTL 741
Query: 1530 YNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDIT 1589
+LEP +Y +++ Q+ +V T P + L + +T
Sbjct: 742 TDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP---------------ISHLHFSHVT 786
Query: 1590 PDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAAD--QREVTIPDLEPSRKYKFLLFG 1647
SV ++W+ P D ++ Y RD + +++ V+ D +R + L+P+ +Y L
Sbjct: 787 SSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVA 846
Query: 1648 IQDGKRRSPVSVEAKTVARGDASPGA-PPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706
+ P+ G + G PP+ ++ +++ T DS+ +SW+ P FD + V
Sbjct: 847 VHGTVTSEPIV--------GSITTGIDPPK--DITISNVTKDSVMVSWSPPVASFDYYRV 896
Query: 1707 QFKDKD----GPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEAR 1762
++ VVP E T+T L+ +Y L + G++ + T
Sbjct: 897 SYRPTQVGRLDSSVVPNTVTE--FTITRLNPATEYEISLNSVRGREESERIC----TLVH 950
Query: 1763 SAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPV 1822
+AMD+ +L T +T L W P G+ +++V+ + + V
Sbjct: 951 TAMDNP-----------VDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILV 999
Query: 1823 EGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEP 1882
+G E + L P+ Y +Y + GP+++ I+ +T PPA
Sbjct: 1000 DGVSEEFRLVDLLPSTHYTATMYATN-----GPLTSGTISTNF------STLLDPPA--- 1045
Query: 1883 HLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESD 1942
LT E T + +SW E +++ + Y DG + + + + I L GL +
Sbjct: 1046 ---NLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLEN 1102
Query: 1943 HRYLVTLYGFSD 1954
Y V L D
Sbjct: 1103 TDYTVLLQAAQD 1114
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 474 bits (1219), Expect = e-132
Identities = 339/1087 (31%), Positives = 513/1087 (47%), Gaps = 83/1087 (7%)
Query: 3170 LTVTGSSPDSLSLSWTVPQGRFDSFTVQY----KDRDGQPQVVRVRGEESEVTVGGLEPG 3225
L + ++ DSL +SW P + D + + Y K+ G+ ++V E+ + GL PG
Sbjct: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQ--IQVPKEQHSYEILGLLPG 324
Query: 3226 RKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQG 3285
KY + L + P + T L V LG V T +S+ + W
Sbjct: 325 TKYIVTLRNVKNEVSSSPQHLLATT-----DLAV---LGTAWVTDETENSLDVEWENPST 376
Query: 3286 PFDSFLVQYRDAQGQPQA---VPVSGDLRA-VAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
D + ++Y GQ A VP S D ++ ++GL P +YK + ++ P+
Sbjct: 377 EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL 436
Query: 3342 VEARTAPDTKPSPRLGELTVTD-ATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVA 3400
+ RT D+ + VTD T D+ +SW + D +VV+Y DG + + V
Sbjct: 437 LNGRTEIDSPTN------VVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVH 490
Query: 3401 ANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETS 3460
++ + GL+P Y+ ++ G + G AD T A E + P +L V E T+
Sbjct: 491 KDESSTVLTGLKPGEAYKVYVWAERGNQ--GSKKAD-TNALTEIDSPANLVTDRVTENTA 547
Query: 3461 SSLRLSWTVAQGPFDSFVVQYRDTDGQP-RAVPVAADQRTVTVEDLEPGKKYKFLLYGLL 3519
+ +SW Q D +VV+Y D Q R V V +Q + + L PG +Y ++
Sbjct: 548 T---ISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
Query: 3520 GGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMR-LSWSVAQ 3578
G + E A AP + P+ VTD ++M +SW Q
Sbjct: 605 GDR--------------ESKKADTNAPTDIDSPKN------LVTDRVTENMATVSWDPVQ 644
Query: 3579 GPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEG 3638
D +VV+Y G+ + + V +QS +++GL P Y +H + G ++
Sbjct: 645 AAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYM-----VHVWAQKGDQESKK 699
Query: 3639 TTGLAPAGQTSEESRPRLSQLSVTD-VTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEP 3697
A QT +S L VTD VT + ++W+ D +++R+
Sbjct: 700 ADTKA---QTDIDSPQNL----VTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGET-- 750
Query: 3698 HPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESP 3757
RE+ V + S VL LR G Y++ ++ +G ++ A+T ++SP
Sbjct: 751 -------REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQT---DIDSP 800
Query: 3758 RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGA 3817
++L + E +A V+W P + D + V Y A+G E + V V + + L GL PG
Sbjct: 801 QNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG-ETREVPVGKEQSSTVLTGLRPGM 859
Query: 3818 RYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV 3877
Y V V + +G +ES+ T DGP L +TE A + W P Q +D Y V+
Sbjct: 860 EYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRY 919
Query: 3878 TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDL 3937
T+ + L L Y V +G + A T L+ PR+L
Sbjct: 920 TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNL 979
Query: 3938 EAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNA 3997
VT +LTWT P + GY+L++ P G +E+ L L GL +Y
Sbjct: 980 RPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPV 1039
Query: 3998 RLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVF 4057
L A G VST+ +T G R P P DC + QN AS TI+L+G+ RPL V+
Sbjct: 1040 SLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDASRPLQVY 1099
Query: 4058 CDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQA--GDYS 4115
CDMETDGGGW+VFQRR GQ DF++ W Y GFG+ EFWLG + LH+LT Y
Sbjct: 1100 CDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYE 1159
Query: 4116 MRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNS 4175
+RVDL+ +E+ +A YD F V S+ E Y+L + Y GTAGD+++YH+G F+ DRD +
Sbjct: 1160 VRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDI 1219
Query: 4176 LLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNF 4235
L +CA+++ G WWY+NCH AN NG YG T +GV+W WKG EFS+P+ E+K+RP +
Sbjct: 1220 ALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPHGY 1279
Query: 4236 -RSPAGG 4241
R P G
Sbjct: 1280 SREPVLG 1286
Score = 309 bits (791), Expect = 4e-83
Identities = 273/1070 (25%), Positives = 420/1070 (39%), Gaps = 148/1070 (13%)
Query: 612 VSEDCSIRTC-------PSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662
+ E CS + C +C G G E C C+ G GP C CP C G GRC
Sbjct: 122 MKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRC 181
Query: 663 VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722
V G CLCH Y G DCG ACP C C G C C E F DC+ + CPGD
Sbjct: 182 VDGRCLCHEPYVGADCGYP-----ACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGD 236
Query: 723 CRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQ 782
C G G C G C C++G+ G DC +V T +G+++ E ++ W P+ VD Y +
Sbjct: 237 CSGHGFCDTGECYCEEGFTGLDCA-QVVTPQGLQLLKNTEDSLLVSWEPS-SQVDHYLLS 294
Query: 783 FIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDG 842
+ P + S +VP +Y+ GL PG +Y VT+R ++ P TT +
Sbjct: 295 YYPLGKELSGK-QIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAV 353
Query: 843 PQDLRVVAVTPTTLELGWLRPQAEVDRFVVSY-VSAGNQRVRLEVPPEADGTL---LTDL 898
V T +L++ W P EVD + + Y G + + VP +D +T L
Sbjct: 354 LGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGL 413
Query: 899 MPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQ 958
PG EY +TV RG P+ L G T+ P+
Sbjct: 414 HPGTEYKITVVPMRG-----------ELEGKPILLNGRTEIDSPTNV------------- 449
Query: 959 RPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVP 1018
V R V W + +R +G E + D ++
Sbjct: 450 ---------VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG-DTKEMAVHKDESSTVLT 499
Query: 1019 PPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDR-TSDS 1077
PG Y++ + QG D + P L VTDR T ++
Sbjct: 500 GLKPGEAYKVYVWAERGN---------QGSKKADTNALTEIDSPANL----VTDRVTENT 546
Query: 1078 LLLRWTVPEGEFDSFVIQYKDRDGQ-PQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGK 1136
+ W + D +V++Y D Q + V V Q S V+T L PG +Y ++ G
Sbjct: 547 ATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606
Query: 1137 KRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDR 1196
+ E+K + P+ P NL T + +SW + D ++V+Y
Sbjct: 607 R-------ESKKADTNAPTDIDSPK--NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSA 657
Query: 1197 DGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRP 1256
G + VPV + S V++ L P +Y ++ A +K +
Sbjct: 658 GGETREVPVGKEQSSTVLTGLRPGMEYMVHVW------------AQKGDQESKKADTKAQ 705
Query: 1257 EFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQ-GQPQAVPVAGDENEVT 1315
++ P L VT + +SW + D ++V+Y A+ G+ + VPV +++
Sbjct: 706 TDIDSP--QNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTV 763
Query: 1316 VPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLL 1375
+ GL P +Y ++++ +G Q ES A T Q D+D SP L T+ +
Sbjct: 764 LTGLRPGVEYTVHVWAQKGAQ----ESKKADTKAQTDID---SPQNLVTD--------WV 808
Query: 1376 GELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHK 1435
E T T S W Q + D + V Y +G R V VG ++S + GL PG +
Sbjct: 809 TENTATVS--------WDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGME 860
Query: 1436 YKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTD-VTPNSVGLSW 1494
Y +H++ Q+ S T Q E P VTD VT N +SW
Sbjct: 861 YTVHVW----AQKGNQESKKADTKAQTEIDGPKN-----------LVTDWVTENMATVSW 905
Query: 1495 TVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPL 1554
+ D ++V+Y DG+ + VPV + + L P +Y ++++ Q
Sbjct: 906 DPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKA 965
Query: 1555 SVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR 1614
T PP L + +T L+WT P + +++ Y+
Sbjct: 966 DTKAQTELDPPR---------------NLRPSAVTQSGGILTWTPPSAQIHGYILTYQFP 1010
Query: 1615 DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTV 1664
DG + + + + + + LE Y L + G+R VS TV
Sbjct: 1011 DGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
Score = 230 bits (587), Expect = 2e-59
Identities = 208/936 (22%), Positives = 375/936 (40%), Gaps = 166/936 (17%)
Query: 1999 TPDSLSLSWTVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056
T DSL +SW P Q DH+L+ Y + K ++VP + I GL P KY + L
Sbjct: 274 TEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLR 332
Query: 2057 GFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWT 2116
P ++ T + +LG VT + +SL + W
Sbjct: 333 NVKNEVSSSPQHLLATT--------------------DLAVLGTAWVTDETENSLDVEWE 372
Query: 2117 VPQGRFDSFTVQYKDRDGRP----QVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2172
P D + ++Y G+ V + +S + GL PG +YK+ + +
Sbjct: 373 NPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEG 432
Query: 2173 GPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGD 2232
P+ G T E +SP + +T D+ ++SW + D ++V++ + D
Sbjct: 433 KPILLNGRT--EIDSPT---------NVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD 481
Query: 2233 GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPAS 2292
G K + V E ++GL+P YK+ ++ G Q G + A
Sbjct: 482 GDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQ-------------GSKKADTNAL 528
Query: 2293 TEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGH 2352
TE +P + R+ E T T +SW + D ++V+Y + D Q + G
Sbjct: 529 TEIDSPANLVTDRVTENTAT--------ISWDPVQATIDKYVVRYTSADDQETREVLVGK 580
Query: 2353 EDRVTI-SGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEE 2411
E T+ +GL P +Y ++++ G + + + +T +PT+ +++P+
Sbjct: 581 EQSSTVLTGLRPGVEYTVHVWAQKGDRE----------SKKADTNAPTD--IDSPK---- 624
Query: 2412 PLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEP 2471
L + + ++SW Q D + V+Y G + V VG E+S + GL P
Sbjct: 625 ----NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRP 680
Query: 2472 GRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVT 2531
G +Y +H++ A + D + + T+ T+ P L
Sbjct: 681 GMEYMVHVW-----------------AQKGDQESKKADTKAQTDIDSPQ------NLVTD 717
Query: 2532 GSSPDSLSLSWTVPQGRFDSFTVQYKD-RDGRPQAVRVGGQESKVTVRGLEPGRKYKMHL 2590
+ + ++SW + D + V+Y +DG + V VG ++S + GL PG +Y +H+
Sbjct: 718 RVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHV 777
Query: 2591 Y---GLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLS 2647
+ G E ++ A+T +P+ L T ++ ++S
Sbjct: 778 WAQKGAQESKK-------------ADTKAQTDIDSPQ--------NLVTDWVTENTATVS 816
Query: 2648 WTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGP 2707
W + D ++V Y + +G+ + V V + ++GL P +Y ++++ G Q
Sbjct: 817 WDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQ---- 872
Query: 2708 ISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFT 2767
E + T+ TE P L + + ++SW Q D +
Sbjct: 873 ----------ESKKADTKAQTEIDGPK------NLVTDWVTENMATVSWDPVQATIDKYM 916
Query: 2768 VQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAE 2827
V+Y DG + + V E S + GL PG +Y +H++ + G E +
Sbjct: 917 VRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVW-----------AQKGAQESKKA 965
Query: 2828 TTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVR 2887
T+A T +PP R +T + L+W P Q +++ Y+ DG K ++
Sbjct: 966 DTKA--QTELDPPRNLRPSAVTQSGGI-----LTWTPPSAQIHGYILTYQFPDGTVKEMQ 1018
Query: 2888 VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPIS 2923
+ + + GLE Y ++L F GG+R +S
Sbjct: 1019 LGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVS 1054
Score = 228 bits (580), Expect = 1e-58
Identities = 206/955 (21%), Positives = 384/955 (40%), Gaps = 149/955 (15%)
Query: 2528 LTVTGSSPDSLSLSWTVPQGRFDSFTVQY----KDRDGRPQAVRVGGQESKVTVRGLEPG 2583
L + ++ DSL +SW P + D + + Y K+ G+ ++V ++ + GL PG
Sbjct: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQ--IQVPKEQHSYEILGLLPG 324
Query: 2584 RKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDS 2643
KY + L + P + T+ LG +TD T +S
Sbjct: 325 TKYIVTLRNVKNEVSSSPQHLLATTDLAV------------------LGTAWVTDETENS 366
Query: 2644 LSLSWTVPEGQFDHFLVQYRNGDGQPKA-VRVPGHEDGVT---ISGLEPDHKYKMNLYGF 2699
L + W P + D++ ++Y GQ A V VP D + I+GL P +YK+ +
Sbjct: 367 LDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPM 426
Query: 2700 HGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIP 2759
G PI + G T + T T+ TE D+ ++SW
Sbjct: 427 RGELEGKPILLNGRTEIDSPTNVVTDRVTE--------------------DTATVSWDPV 466
Query: 2760 QGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
Q D + V+Y DG + M V +ES + GL+PG YK++++ + T
Sbjct: 467 QAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTN 526
Query: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG 2879
+TE ++ P N L T ++ ++SW + D ++V+Y +
Sbjct: 527 ALTEIDS------------PAN------LVTDRVTENTATISWDPVQATIDKYVVRYTSA 568
Query: 2880 DGQ-PKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
D Q + V V + ++GL P +Y ++++ G + + + +T APT
Sbjct: 569 DDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRE----------SKKADTNAPT 618
Query: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
+ ++P+ L + + ++SW Q D + V+Y G + V V
Sbjct: 619 D--IDSPK--------NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGK 668
Query: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
E+S + GL PG +Y +H++ Q +A+T +P+ +
Sbjct: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQE------------SKKADTKAQTDIDSPQNLVT 716
Query: 3059 PRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLE 3117
R+ T + ++SW D ++V+Y + DG+ + V V + ++GL
Sbjct: 717 DRV--------TENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLR 768
Query: 3118 PDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSP 3177
P +Y ++++ G Q T+ ++P L +
Sbjct: 769 PGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQ------------------NLVTDWVTE 810
Query: 3178 DSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLY---G 3234
++ ++SW Q D + V Y +G+ + V V E+S + GL PG +Y +H++ G
Sbjct: 811 NTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKG 870
Query: 3235 LHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQY 3294
E ++ + I P L VT + +SW Q D ++V+Y
Sbjct: 871 NQESKKADTKAQTEIDGP-----------KNLVTDWVTENMATVSWDPVQATIDKYMVRY 919
Query: 3295 RDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSP 3354
A G+ + VPV + + ++GL P +Y ++ + + +A+T D +
Sbjct: 920 TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNL 979
Query: 3355 RLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPS 3414
R +T + L+WT P + +++ Y+ DG ++ + + + +QGLE
Sbjct: 980 RPSAVTQSGGI-----LTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQG 1034
Query: 3415 RKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV 3469
Y L G +R +S +T PH + + ++ S++ +T+
Sbjct: 1035 ATYPVSLVAFKGGRRSRNVSTTLSTVGARF---PHPSDCSQVQQNSNAASGLYTI 1086
Score = 226 bits (576), Expect = 4e-58
Identities = 220/914 (24%), Positives = 370/914 (40%), Gaps = 134/914 (14%)
Query: 1068 LTVTDRTSDSLLLRWTVPEGEFDSFVIQY----KDRDGQPQVVPVEGPQRSAVITSLDPG 1123
L + T DSLL+ W P + D +++ Y K+ G+ VP E Q S I L PG
Sbjct: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKE--QHSYEILGLLPG 324
Query: 1124 RKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPE 1183
KY L + P +L +D + LG WVTD T +SL + W P
Sbjct: 325 TKYIVTLRNVKNEVSSSP----QHLLATTDLAV-----LGTAWVTDETENSLDVEWENPS 375
Query: 1184 GQFDTFMVQYRDRDGRPQVVPVEGPERS-----FVVSSLDPDHKYRFTLFGIANKKRYGP 1238
+ D + ++Y G+ +V V P+ S + ++ L P +Y+ T+ + + P
Sbjct: 376 TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKP 434
Query: 1239 LTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDA 1298
+ +G T ++ P + VT D+ +SW Q D ++V+Y A
Sbjct: 435 ILLNGRTE------------IDSPT--NVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA 480
Query: 1299 QGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPS 1358
G + + V DE+ + GL P YK+ ++ RG Q +K A + E S
Sbjct: 481 DGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQG-------SKKADTNALTEIDS 533
Query: 1359 PTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGR-PRAVR 1417
P L T+ + ++ ++ W Q + D + V+Y D + R V
Sbjct: 534 PANLVTDR----------------VTENTATISWDPVQATIDKYVVRYTSADDQETREVL 577
Query: 1418 VGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRL 1477
VG ++S + GL PG +Y +H++ +G R E T +P +
Sbjct: 578 VGKEQSSTVLTGLRPGVEYTVHVWA-QKGDR--------------ESKKADTNAPTDIDS 622
Query: 1478 GELTVTD-VTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPER 1536
+ VTD VT N +SW + D ++V+Y G+ + VPV +Q + L P
Sbjct: 623 PKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGM 682
Query: 1537 KYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLS 1596
+Y ++++ Q + T+ P L +T + +S
Sbjct: 683 EYMVHVWAQKGDQE---------SKKADTKAQTDIDSPQ------NLVTDRVTENMATVS 727
Query: 1597 WTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRS 1655
W D +VV+Y +DG+ + VPV +Q + L P +Y ++ Q G + S
Sbjct: 728 WDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWA-QKGAQES 786
Query: 1656 PVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG-P 1714
+A T A+ D +P L WVT+ T +SW + D +VV + +G
Sbjct: 787 K---KADTKAQTDID--SPQNLVTDWVTENT---ATVSWDPVQATIDRYVVHYTSANGET 838
Query: 1715 QVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPP 1774
+ VPV + S +T L G +Y ++ G + + T+A++ +D P
Sbjct: 839 REVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDG------P 888
Query: 1775 KPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGL 1834
K L VT+N +SW + D ++V+Y DG+ + VPV + GL
Sbjct: 889 K-----NLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGL 943
Query: 1835 DPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATS 1894
P Y + ++ A +E + +T A T P +L V ++
Sbjct: 944 RPGMEYMVHVW--------------AQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGG 989
Query: 1895 HTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSD 1954
L+W + + + Y DG ++ +++G + L GLE Y V+L F
Sbjct: 990 ---ILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKG 1046
Query: 1955 GKHVGPVHVEALTV 1968
G+ V TV
Sbjct: 1047 GRRSRNVSTTLSTV 1060
Score = 225 bits (574), Expect = 6e-58
Identities = 217/959 (22%), Positives = 370/959 (38%), Gaps = 141/959 (14%)
Query: 2854 TPDSLSLSWMVPEGQFDHFLVQYR--NGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLY 2911
T DSL +SW P Q DH+L+ Y + K ++VP + I GL P KY + L
Sbjct: 274 TEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLR 332
Query: 2912 GFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWT 2971
P ++ T + +LG VT + +SL + W
Sbjct: 333 NVKNEVSSSPQHLLATT--------------------DLAVLGTAWVTDETENSLDVEWE 372
Query: 2972 IPQGRFDSFTVQYKDRDGRP----QVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRV 3027
P D + ++Y G+ V + +S + GL PG +YK+ + +
Sbjct: 373 NPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEG 432
Query: 3028 GPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD-ATPDSLSLSWMVPEGQFD 3086
P+ G T E ++ V VTD T D+ ++SW + D
Sbjct: 433 KPILLNGRT----EIDSPTNV-----------------VTDRVTEDTATVSWDPVQAVID 471
Query: 3087 HFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEE 3146
++V+Y + DG K + V E ++GL+P YK+ ++ G Q +TE
Sbjct: 472 KYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEI 531
Query: 3147 ETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQ-P 3205
++P+ L + ++ ++SW Q D + V+Y D Q
Sbjct: 532 DSPA------------------NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQET 573
Query: 3206 QVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGE 3265
+ V V E+S + GL PG +Y +H++ +G R + + +P
Sbjct: 574 REVLVGKEQSSTVLTGLRPGVEYTVHVWA-QKGDRESKKADTNAPTDIDSP-------KN 625
Query: 3266 LAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYK 3325
L VT + +SW Q D ++V+Y A G+ + VPV + + ++GL P +Y
Sbjct: 626 LVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYM 685
Query: 3326 FLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVV 3385
++ + + +A+T D SP+ L T + +SW D +VV
Sbjct: 686 VHVWAQKGDQESKKADTKAQTDID---SPQ--NLVTDRVTENMATVSWDPVRATIDRYVV 740
Query: 3386 QYKD-KDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEK 3444
+Y KDG + VPV Q + GL P +Y ++ G + T A +
Sbjct: 741 RYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE---SKKADTKAQTDI 797
Query: 3445 ELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVED 3504
+ P +L V E T++ +SW Q D +VV Y +G+ R VPV +Q + +
Sbjct: 798 DSPQNLVTDWVTENTAT---VSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTG 854
Query: 3505 LEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTD 3564
L PG +Y ++ G +E A A + P+ VTD
Sbjct: 855 LRPGMEYTVHVWAQKGN--------------QESKKADTKAQTEIDGPKN------LVTD 894
Query: 3565 TTPDSM-RLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLY 3623
++M +SW Q D ++V+Y +G+ + + V + S +++GL P Y ++
Sbjct: 895 WVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVW 954
Query: 3624 GLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSF 3683
+ + T L P PR L + VT S L W P +
Sbjct: 955 AQKGAQESKKADTKAQTELDP---------PR--NLRPSAVTQSGGILTWTPPSAQIHGY 1003
Query: 3684 LLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSI 3743
+L + P + +E+ + L+ L G Y ++L +G ++ ++
Sbjct: 1004 ILTYQFPDGTV----------KEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNV 1053
Query: 3744 QGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVD 3802
T T+ P D S++++ S + A Y D P V D
Sbjct: 1054 STTLSTVGARFPHPSDC--SQVQQNS---------NAASGLYTIYLHGDASRPLQVYCD 1101
Score = 216 bits (551), Expect = 3e-55
Identities = 205/922 (22%), Positives = 372/922 (40%), Gaps = 157/922 (17%)
Query: 1589 TPDSVGLSWTVPEGEFDSFVVQY----KDRDGQPQVVPVAADQREVTIPDLEPSRKYKFL 1644
T DS+ +SW P + D +++ Y K+ G+ VP +Q I L P KY
Sbjct: 274 TEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVP--KEQHSYEILGLLPGTKYIVT 330
Query: 1645 LFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSF 1704
L +++ SP + A T D + LG WVTD T +SL + W P + D +
Sbjct: 331 LRNVKNEVSSSPQHLLATT----DLAV-----LGTAWVTDETENSLDVEWENPSTEVDYY 381
Query: 1705 VVQFKDKDGPQV----VPVEGHERS-VTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTT 1759
+++ G +V VP +S +T L G +Y+ + + G+ P+ +G T
Sbjct: 382 KLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRT 441
Query: 1760 EARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQV 1819
E S + + VT+++ +SW + D +VV+Y DG +
Sbjct: 442 EIDSPTN---------------VVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKE 486
Query: 1820 VPVEGSLREVSVPGLDPAHRYKLLLYGL--HHGKRVGPISAVAITAGREETETETTAPTP 1877
+ V + GL P YK+ ++ + G + +A+ TE +P
Sbjct: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNAL----------TEIDSPA- 535
Query: 1878 PAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ-LQMVRIGGDRNDITL 1936
L + T +T +SW + D + ++YT D Q + V +G +++ L
Sbjct: 536 --------NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVL 587
Query: 1937 SGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT 1996
+GL Y V HV A E K ++ T P P+ L
Sbjct: 588 TGLRPGVEYTV--------------HVWAQKGDRESKKAD--TNAPTDIDSPK--NLVTD 629
Query: 1997 DATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056
T + ++SW + D ++V+Y + G+ + V V + ++GL P +Y ++++
Sbjct: 630 RVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVW 689
Query: 2057 GFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWT 2116
G Q S T A+ + SP L + + ++SW
Sbjct: 690 AQKGDQE----SKKADTKAQTDIDSPQN----------------LVTDRVTENMATVSWD 729
Query: 2117 VPQGRFDSFTVQYKD-RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY---GLHEGRRV 2172
+ D + V+Y +DG + V VG E+S + GL PG +Y +H++ G E ++
Sbjct: 730 PVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKA 789
Query: 2173 GPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGD 2232
+ + +P+ D +T ++ ++SW + D ++V + + +
Sbjct: 790 DTKAQTDIDSPQNLVTDW--------------VTENTATVSWDPVQATIDRYVVHYTSAN 835
Query: 2233 GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPAS 2292
G+ + V V + ++GL P +Y ++++ G Q + A
Sbjct: 836 GETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQE-------------SKKADTKAQ 882
Query: 2293 TEPPTPEPPIKPRLEELTVTD-ATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPG 2351
TE P+ VTD T + ++SW + D ++V+Y + DG+ + V
Sbjct: 883 TEIDGPKN---------LVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGK 933
Query: 2352 HEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEE 2411
++GL P +Y ++++ G Q + + +T + TE +PP
Sbjct: 934 EHSSTVLTGLRPGMEYMVHVWAQKGAQE----------SKKADTKAQTEL-----DPPRN 978
Query: 2412 PLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEP 2471
+T +G L+WT P + + + Y+ DG + +++G E+ + GLE
Sbjct: 979 LRPSAVTQSGGI-----LTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQ 1033
Query: 2472 GRKYKMHLYGLHEGRRVGPVST 2493
G Y + L GRR VST
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVST 1055
Score = 212 bits (539), Expect = 7e-54
Identities = 203/845 (24%), Positives = 342/845 (40%), Gaps = 134/845 (15%)
Query: 1065 LGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAV-----ITS 1119
LG VTD T +SL + W P E D + ++Y GQ +V V P+ S IT
Sbjct: 354 LGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITG 412
Query: 1120 LDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDP-TPDSLHLS 1178
L PG +YK + G+ P++ + S + VTD T D+ +S
Sbjct: 413 LHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNV----------VTDRVTEDTATVS 462
Query: 1179 WTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGP 1238
W + D ++V+Y DG + + V E S V++ L P Y+ ++ A + G
Sbjct: 463 WDPVQAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVW--AERGNQGS 520
Query: 1239 LTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDA 1298
AD E ++ P L VT ++ +SW Q D ++V+Y A
Sbjct: 521 KKADTNALTE----------IDSP--ANLVTDRVTENTATISWDPVQATIDKYVVRYTSA 568
Query: 1299 QGQPQAVPVAGDENEVTV-PGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP 1357
Q + G E TV GL P +Y ++++ +G + ES A T D+D
Sbjct: 569 DDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR----ESKKADTNAPTDID--- 621
Query: 1358 SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVR 1417
SP L T+ + + ++ W Q + D + V+Y G R V
Sbjct: 622 SPKNLVTDRV----------------TENMATVSWDPVQAAIDKYVVRYTSAGGETREVP 665
Query: 1418 VGGKESEVTVGGLEPGHKYKMHLY---GLHEGQRVGPVSAVGVTAPQQEETPPATESPLE 1474
VG ++S + GL PG +Y +H++ G E ++ + + +PQ
Sbjct: 666 VGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQN------------ 713
Query: 1475 PRLGELTVTD-VTPNSVGLSWTVPEGQFDSFIVQYKD-KDGQPQVVPVAADQREVTVYNL 1532
VTD VT N +SW D ++V+Y KDG+ + VPV +Q + L
Sbjct: 714 ------LVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGL 767
Query: 1533 EPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTD-ITPD 1591
P +Y ++++ Q + T+ P + VTD +T +
Sbjct: 768 RPGVEYTVHVWAQKGAQE---------SKKADTKAQTDIDSP-------QNLVTDWVTEN 811
Query: 1592 SVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDG 1651
+ +SW + D +VV Y +G+ + VPV +Q + L P +Y ++ +
Sbjct: 812 TATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGN 871
Query: 1652 KRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDK 1711
+ +A+T G P L WVT+ + +SW + D ++V++
Sbjct: 872 QESKKADTKAQTEIDG------PKNLVTDWVTE---NMATVSWDPVQATIDKYMVRYTSA 922
Query: 1712 DGP-QVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGT 1770
DG + VPV S +T L G +Y ++ G + + T+A++ +D
Sbjct: 923 DGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQE----SKKADTKAQTELD---- 974
Query: 1771 KRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVS 1830
PP+ L+ + VTQ+ L+WT P Q +++ Y+ DG + + + + +
Sbjct: 975 --PPR-----NLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFA 1027
Query: 1831 VPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVE 1890
+ GL+ Y P+S VA GR TT T A PH + +
Sbjct: 1028 LQGLEQGATY--------------PVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQV 1073
Query: 1891 EATSH 1895
+ S+
Sbjct: 1074 QQNSN 1078
Score = 168 bits (426), Expect = 9e-41
Identities = 86/218 (39%), Positives = 109/218 (50%), Gaps = 33/218 (15%)
Query: 68 EKQVVFTHRINLP-PSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGG-C 125
E+ ++F H I L P C LA VQ L R++ LEE + +KEQC+ C
Sbjct: 81 EQNIIFRHNIRLQTPQKDCE---------LAGSVQDLLARVKKLEEEMVEMKEQCSAQRC 131
Query: 126 CPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASG 185
C G TD+ CS HG F L C+C CE G GP C
Sbjct: 132 CQ-------GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERL--------------- 169
Query: 186 SCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCS 245
+CP C+ GRCV GRC+C Y G CG+P+CP +C G G CV+GVC C F DCS
Sbjct: 170 ACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS 229
Query: 246 QRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG 283
++ CP CS G C+ G C C+ G+TG DC P+G
Sbjct: 230 EKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQG 267
Score = 146 bits (368), Expect = 5e-34
Identities = 63/142 (44%), Positives = 80/142 (56%), Gaps = 9/142 (6%)
Query: 521 EDCGSRRC-------PGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571
E C ++RC C GHG E C C+ G G C +CPG C G G+C+D
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 572 GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631
GRC+C + Y G DCG CP +CS HG C GVC C E ++SEDCS + CP +C G G C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 632 EEGRCLCDPGYTGPTCATRMCP 653
+ G C C+ G+TG CA + P
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTP 265
Score = 143 bits (361), Expect = 3e-33
Identities = 61/128 (47%), Positives = 71/128 (55%), Gaps = 2/128 (1%)
Query: 437 RDCRGRGR--CENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494
R C G G E C C G G C +CPG C G GRC GRC+C Y G DCG
Sbjct: 140 RHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGY 199
Query: 495 RACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
ACP +C G G CV G C C+ F EDC +RCPGDC GHG C+ G C C+ G++G DC
Sbjct: 200 PACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDC 259
Query: 555 STRSCPGG 562
+ P G
Sbjct: 260 AQVVTPQG 267
Score = 142 bits (358), Expect = 7e-33
Identities = 64/150 (42%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Query: 462 GVRSCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFT 519
GV C G G E+ C C G G C ACPG C G GRCVDGRC+C+ +
Sbjct: 134 GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYV 193
Query: 520 GEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDG 579
G DCG CP +C GHG C GVC C + EDCS + CPG C G G C G C CE+G
Sbjct: 194 GADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253
Query: 580 YSGEDCGVRQCPNDCSQHGVCQDGVCICWE 609
++G DC P +D + + WE
Sbjct: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSWE 283
Score = 141 bits (356), Expect = 1e-32
Identities = 62/142 (43%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 366 EDCSTRTC-------PRDCRGRGR--CEDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
E CS + C R C G G E C C+ G G C +CPG C+ GRC D
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476
GRC+C Y G DCG ACP +C G G C GVC C+ + EDC + CPGDC G G C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 477 ESGRCMCWPGYTGRDCGTRACP 498
++G C C G+TG DC P
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTP 265
Score = 130 bits (328), Expect = 2e-29
Identities = 61/149 (40%), Positives = 72/149 (48%), Gaps = 2/149 (1%)
Query: 276 GMRSCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYT 333
G+ R CS G E C C G G C +CP CS GRC DGRC+C Y
Sbjct: 134 GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYV 193
Query: 334 GEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTG 393
G DCG +CP +C G CV G C C + EDCS + CP DC G G C+ GEC C+ G
Sbjct: 194 GADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253
Query: 394 YSGDDCGVRSCPGDCNQRGRCEDGRCVCW 422
++G DC P ED V W
Sbjct: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSW 282
Score = 125 bits (314), Expect = 9e-28
Identities = 54/143 (37%), Positives = 68/143 (47%), Gaps = 9/143 (6%)
Query: 304 EDCGVRSCPRGCSQRGRCKDGR---------CVCDPGYTGEDCGTRSCPWDCGEGGRCVD 354
E C + C +G + R G C C+ G G C +CP C GRCVD
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 355 GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRC 414
GRC+C Y G DC CP +C G G C G C C + +DC + CPGDC+ G C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 415 EDGRCVCWPGYTGTDCGSRACPR 437
+ G C C G+TG DC P+
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTPQ 266
Score = 122 bits (307), Expect = 6e-27
Identities = 48/106 (45%), Positives = 58/106 (54%)
Query: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571
C C G G C CPG C GHG C DG C+C Y G DC +CP C G G+C+
Sbjct: 155 CHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVR 214
Query: 572 GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS 617
G C C + + EDC ++CP DCS HG C G C C EG+ DC+
Sbjct: 215 GVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDCA 260
Score = 122 bits (305), Expect = 1e-26
Identities = 51/118 (43%), Positives = 60/118 (50%), Gaps = 2/118 (1%)
Query: 222 CQGRGRCVQGVCVCRA--GFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRS 279
C G G C C G GP C + +CP CS GRC GRC+C Y G DCG +
Sbjct: 142 CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPA 201
Query: 280 CPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC 337
CP CS G C G C C+ + EDC + CP CS G C G C C+ G+TG DC
Sbjct: 202 CPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDC 259
Score = 121 bits (304), Expect = 1e-26
Identities = 57/151 (37%), Positives = 72/151 (47%), Gaps = 9/151 (5%)
Query: 244 CSQRSCPRGCSQRGR-CEGG--------RCVCDPGYTGDDCGMRSCPRGCSQRGRCENGR 294
CS + C +G + R C G C C+ G G C +CP CS GRC +GR
Sbjct: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGR 185
Query: 295 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVD 354
C+C+ Y G DCG +CP CS G C G C C + EDC + CP DC G C
Sbjct: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
Query: 355 GRCVCWPGYTGEDCSTRTCPRDCRGRGRCED 385
G C C G+TG DC+ P+ + ED
Sbjct: 246 GECYCEEGFTGLDCAQVVTPQGLQLLKNTED 276
Score = 121 bits (304), Expect = 1e-26
Identities = 54/126 (42%), Positives = 62/126 (49%), Gaps = 2/126 (1%)
Query: 400 GVRSCPGDCNQRGR--CEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYS 457
GV C+ G E C C G G C ACP C G GRC +G C+C+ Y
Sbjct: 134 GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYV 193
Query: 458 GEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPG 517
G DCG +CP +C G G C G C C + DC + CPGDC G G C G C C G
Sbjct: 194 GADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253
Query: 518 FTGEDC 523
FTG DC
Sbjct: 254 FTGLDC 259
Score = 121 bits (303), Expect = 2e-26
Identities = 57/142 (40%), Positives = 64/142 (45%), Gaps = 9/142 (6%)
Query: 552 EDCSTRSCPGG-------CRGRG--QCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD 602
E CS + C G C G G C CE+G G C CP CS HG C D
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 603 GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662
G C+C E YV DC CP NC G G C G C C + C+ + CP DC G G C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 663 VQGVCLCHVGYGGEDCGQEEPP 684
G C C G+ G DC Q P
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTP 265
Score = 114 bits (285), Expect = 2e-24
Identities = 45/105 (42%), Positives = 54/105 (51%)
Query: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
C C G G C CP C G GRC DG C+C Y G DCG +CP +C+ G C
Sbjct: 155 CHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVR 214
Query: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDC 461
G C C + DC + CP DC G G C+ G C C G++G DC
Sbjct: 215 GVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDC 259
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 338 bits (867), Expect = 7e-92
Identities = 430/1924 (22%), Positives = 730/1924 (37%), Gaps = 329/1924 (17%)
Query: 1378 LTVTGSSPDSLSLFWTVPQGSFDS-FTVQYKDRD--GRPRAVRVGGKESEVTVGGLEPGH 1434
+T T S P+S + W PQ S S + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 1435 KYKMHL-----YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGEL-TVTDVTPN 1488
Y+ L YG E R + + P T +P P + +VT++T +
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
Query: 1489 SVGLSWTVPEGQFDSFIVQYK--DKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGL- 1545
S +SW F V+Y+ ++ +PQ + + + V + +L P RKY +N+Y +
Sbjct: 735 SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
Query: 1546 HDGQRMGPLSVVIVTAP-LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
DG++ LS TAP PP P TV + S+ + W+ P+
Sbjct: 795 EDGEQSLILSTSQTTAPDAPPDP----------------TVDQVDDTSIVVRWSRPQAPI 838
Query: 1605 DSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKT 1663
+ + Y +G + + VT+ DL+P +Y ++ +++ + +PV ++ +T
Sbjct: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Query: 1664 VARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP----QVVPV 1719
+ PR +L + T + + WT PE + V + P Q +P+
Sbjct: 899 TGTPRSDTVPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 1720 EGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLG 1779
VT L G Y F ++ + + PLTA TT+ + +
Sbjct: 957 S-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN------------- 1002
Query: 1780 EELQVTTVTQNSVGLSWTVPEGQFDSFVVQYK-DRDGQPQVVPVEGSLREVSVPGLDPAH 1838
LQ T ++V + WT P Q + + R GQP+ V S+ + + L PA
Sbjct: 1003 --LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
Query: 1839 RYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLH 1898
Y +S VAI G +E+ T T P + E T T+
Sbjct: 1061 EYT--------------VSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIV 1104
Query: 1899 LSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV 1958
++W T F++ G + D I +SGL Y+ T+ DG+
Sbjct: 1105 ITW--TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 1959 GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT---DATPD--SLSLSWTVPEGQ 2013
+A V + P PPT P G LTV+ TPD ++ T GQ
Sbjct: 1163 -----DAPIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
Query: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073
+ L + + D + T L P +Y +++Y + P+S
Sbjct: 1217 QGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS----- 1260
Query: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR- 2132
+T P E P L +L+ + S+ L WT S + Y+
Sbjct: 1261 ----DTIIP-----------EVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITV 1302
Query: 2133 ----DGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEES 2187
+G P V TV GLEPG Y + + L G P + TA
Sbjct: 1303 VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP--- 1359
Query: 2188 PDAPLAKLRLGQMTVRDITSDSLSLSWTVPEG-QFDHFLVQFK--NGDGQPKAVRVPGHE 2244
P LR +I D++ ++W P +FLV++ + + + +
Sbjct: 1360 ---PPTDLRF-----TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
Query: 2245 DGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKP 2304
+ V ++ L P +Y +++ + P+ G G D PT
Sbjct: 1412 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLR--GRQKTGLDS---------PTG------ 1454
Query: 2305 RLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLE 2362
+ +D T +S ++ W P + +++ ++ G+P+ RVP + +T++ L
Sbjct: 1455 ----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
Query: 2363 PDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGS 2422
P +Y +++ +G EE+P + P + L V +
Sbjct: 1511 PGTEYVVSIVALNG---------------REESPLLIGQQSTVSDVPRD-----LEVVAA 1550
Query: 2423 SPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLY 2480
+P SL +SW P + + Y + G V V G +S T+ GL+PG Y + +Y
Sbjct: 1551 TPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
Query: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
+ GR P S+ ++ + PS ++ VT +S+S+
Sbjct: 1611 AV-TGRGDSPASSKPISINYRTEIDKPS------------------QMQVTDVQDNSISV 1651
Query: 2541 SWTVPQGRFDSF--TVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRR 2598
W + T K+ G + G ++++T+ GL+P +Y + +Y +
Sbjct: 1652 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1711
Query: 2599 LGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHF 2658
P+ VT + R L TD DS+ ++W P+GQ +
Sbjct: 1712 SQPLVQTAVTNID------------------RPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
Query: 2659 LVQYRNG-DGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAA 2716
V Y + DG + P G ED + GL P +Y +++ H P+ TA
Sbjct: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1813
Query: 2717 EEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQY--KDRD 2774
P+PT+L T +P SLS WT P + V+ K++
Sbjct: 1814 ----PAPTDLK----------------FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1853
Query: 2775 GRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPT 2834
G + + + + S V V GL KY++ +Y L + P V T +
Sbjct: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS------- 1906
Query: 2835 TTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVR-VPGHED 2893
PP + R VTDAT ++++SW F V +GQ + R +
Sbjct: 1907 ----PPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVR 1957
Query: 2894 GVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLL 2953
TI+GL+P YK+ LY + R P+ + TA + AP+
Sbjct: 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID----APSN-------------- 1999
Query: 2954 GELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVV--RVRGEESEVTVGGLEPG 3011
L ++P+SL +SW P+ R + ++Y+ P+ V R R +E T+ GLEPG
Sbjct: 2000 --LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 2057
Query: 3012 CKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATP 3071
+Y +++ L Q+ P+ + T +P + P P L + D
Sbjct: 2058 TEYTIYVIALKNNQKSEPLIG---------RKKTDELPQLVTLP--HPNLHGPEILDVPS 2106
Query: 3072 DSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHG 3131
++ G Y G+G +++PG SG +P +M ++ HG
Sbjct: 2107 TVQKTPFVTHPG--------YDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHG 2147
Query: 3132 GQR-VGPVSAIGVTEEETPSPTEPSTEAPEA------------PEEPLLGELTVTGSSP- 3177
+R P +A + P P E P P L TG
Sbjct: 2148 FRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEAL 2207
Query: 3178 DSLSLSWTVPQGRFD-SFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLH 3236
++SW Q + + D +P RV G + T+ GL G Y + + L
Sbjct: 2208 SQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK 2267
Query: 3237 EGQR 3240
+ QR
Sbjct: 2268 DQQR 2271
Score = 307 bits (787), Expect = 1e-82
Identities = 362/1637 (22%), Positives = 630/1637 (38%), Gaps = 236/1637 (14%)
Query: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Y+ L YG E R +T + P T T P PL+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Query: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
Query: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Query: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
Query: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
Query: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
T+ +A T L + T ++ + W P Q + L
Sbjct: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
Query: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
Query: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
Query: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
Query: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
L P +Y +++Y + P+S + PE P L +L+
Sbjct: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTII------------------PEVPQLTDLSFV 1276
Query: 3174 GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGE---------ESEV---TVGG 3221
+ S+ L WT +S T+ G V GE +S V TV G
Sbjct: 1277 DITDSSIGLRWTP----LNSSTII-----GYRITVVAAGEGIPIFEDFVDSSVGYYTVTG 1327
Query: 3222 LEPGRKYKMHLYGLHEGQRVGPVSTVGITA-PLPTPLPVEPRLGELAVAAVTSDSVGLSW 3280
LEPG Y + + L G P + TA P PT +L + D++ ++W
Sbjct: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT---------DLRFTNIGPDTMRVTW 1378
Query: 3281 TVAQG-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRH 3337
+FLV+Y + + + +S AV ++ L P +Y + +
Sbjct: 1379 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1438
Query: 3338 GPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQ 3395
P+ +T D+ + +D T +S + W P + +++ + GR +
Sbjct: 1439 TPLRGRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1493
Query: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455
V ++ +T+ L P +Y + L+GR+ + +T ++P +L V
Sbjct: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEV 1547
Query: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKF 3513
T +SL +SW + + Y +T G + V + T T+ L+PG Y
Sbjct: 1548 VAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1607
Query: 3514 LLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLS 3573
+Y + G D+PA E + + VTD +S+ +
Sbjct: 1608 TVYAVTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1652
Query: 3574 WSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRL 3631
W + P + V NG P G DQ+++ I GL+P+ Y +Y +
Sbjct: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
Query: 3632 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 3691
PL T + RP+ L+ TDV S+++ WE+P G + + + P
Sbjct: 1713 QPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE 1761
Query: 3692 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 3751
E P P G +A L+ LR G+ Y++++ L ++ + GT T
Sbjct: 1762 DGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1813
Query: 3752 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKL 3810
P +P DL+F+++ TS W PP + ++V + P + + + + + +
Sbjct: 1814 P---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
Query: 3811 QGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQN 3868
GL+ +YEV+V +++ S P G +TT+ + P + R + TE + W+
Sbjct: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
Query: 3869 PVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITF 3927
+ + V V A G P+Q Y + L T+Y + L +SP I
Sbjct: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1990
Query: 3928 TTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQ 3985
+T ++AP +L TP + L++W P R GY++ + PG +E++ G+T
Sbjct: 1991 STAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 2050
Query: 3986 LLGLFPSTSYNARLQAM 4002
+ GL P T Y + A+
Sbjct: 2051 ITGLEPGTEYTIYVIAL 2067
Score = 304 bits (779), Expect = 1e-81
Identities = 385/1785 (21%), Positives = 665/1785 (37%), Gaps = 280/1785 (15%)
Query: 2309 LTVTDATPDSLSLSWTVPE-GQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDN 2365
+T T + P+S + W P+ +++++ KN G+ K +PGH + TI GL+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2366 KYKMNLYGF--HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGEL-TVTGS 2422
Y+ L +G Q V + T TP T ++ P PL+ +VT
Sbjct: 676 VYEGQLISIQQYGHQEV---TRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEI 731
Query: 2423 SPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
+ S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
Query: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
+ ED +++ + T AP P +P + ++ T S+ +
Sbjct: 792 QI-----------------SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-----SIVV 829
Query: 2541 SWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRL 2599
W+ PQ + + Y +G + + + VT+ L+PG +Y + +Y + E +
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 2600 GPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG-----Q 2654
PV Q T TP P +L + T +++ WT PE +
Sbjct: 890 TPV-----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYR 938
Query: 2655 FDHFLVQYRNGDGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGV 2713
D V GQ R+P ++GL P Y ++ G+ P++
Sbjct: 939 VDVIPVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
Query: 2714 TAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYK-D 2772
T + T L + ++ + WT P+ + +
Sbjct: 995 TKLDAPT--------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2773 RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAV 2832
R G+P+ V S+ + L+P +Y + L + +G + P +T GV T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKAT-GVF------TTLQ 1086
Query: 2833 PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHE 2892
P ++ P N T+ T ++ ++W P + F + R G V
Sbjct: 1087 PGSSIPPYN---------TEVTETTIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
Query: 2893 DGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEP 2951
+ +SGL P +Y + GQ R PI V PT EA P
Sbjct: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NP 1186
Query: 2952 LLGELTVT---GSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGL 3008
G LTV+ ++PD T T + G V ++S T L
Sbjct: 1187 DTGVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
Query: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068
PG +Y + +Y + KD+ E+ T+ PE P +L +L+ D
Sbjct: 1238 SPGLEYNVSVYTV-----------------KDDKESVPISDTIIPEVP---QLTDLSFVD 1277
Query: 3069 ATPDSLSLSWMVPEGQFDHFLVQYR-----NGDGQPKAVRVPGHEDGV-------TISGL 3116
T S+ L W ++ YR G+G +P ED V T++GL
Sbjct: 1278 ITDSSIGLRWTPLNSST---IIGYRITVVAAGEG------IPIFEDFVDSSVGYYTVTGL 1328
Query: 3117 EPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSS 3176
EP Y +++ G P + T P PT+ L T
Sbjct: 1329 EPGIDYDISVITLINGGESAPTTLTQQTA--VPPPTD----------------LRFTNIG 1370
Query: 3177 PDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLY 3233
PD++ ++W P +F V+Y + V + ++ V + L PG +Y + +
Sbjct: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1430
Query: 3234 GLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQ 3293
++E P+ T L +P ++ + +T++S + W + + ++
Sbjct: 1431 SVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGYRIR 1482
Query: 3294 YRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTK 3351
+ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1541
Query: 3352 PSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQ 3409
P +L V ATP S+ +SW P + + Y + G +Q V ++ T+
Sbjct: 1542 PR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
Query: 3410 GLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV 3469
GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ + W
Sbjct: 1598 GLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP 1655
Query: 3470 AQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPV 3527
+ P + V ++ G + DQ +T+E L+P +Y V
Sbjct: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV--------------V 1701
Query: 3528 SALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQ 3587
S E P + A + P+ L TD DS++++W QG + V
Sbjct: 1702 SVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
Query: 3588 YEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPA 3645
Y L DG++ + GL P + Y + LH+ PL +T +
Sbjct: 1757 YSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI--- 1813
Query: 3646 GQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQR 3705
P + L T VT +SL W P + +R + P + +
Sbjct: 1814 --------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTGPMK 1857
Query: 3706 ELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEI 3765
E+ + S V+ L T Y +++Y L+ + QG TL V PR + ++
Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDA 1916
Query: 3766 RETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVS 3825
ET+ ++W F+V A+G P + R+ + GL PG Y++ + +
Sbjct: 1917 TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1976
Query: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPL 3885
+ S P+ +T D P+ LR L T ++ W+PP+ + Y ++ PG+PP
Sbjct: 1977 LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
Query: 3886 QA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT------------G 3930
+ PG + + L T YT V L+ + P T
Sbjct: 2037 EVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 2095
Query: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 3990
L P L+ +T +T H I LPG TS G
Sbjct: 2096 LHGPEILDVPSTVQKTPFVT---------------HPGYDTGNGIQLPG--TS----GQQ 2134
Query: 3991 PSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNG 4035
PS + + PP + + R P+P + GEE+Q G
Sbjct: 2135 PSVGQQMIFEEHGFRRTTPPTTATPIRHRPR-PYPPNVGEEIQIG 2178
Score = 294 bits (753), Expect = 1e-78
Identities = 379/1729 (21%), Positives = 635/1729 (36%), Gaps = 315/1729 (18%)
Query: 1583 LTVTDITPDSVGLSWTVPE-GEFDSFVVQYKDRD--GQPQVVPVAADQREVTIPDLEPSR 1639
+T T P+S + W P+ ++++++ ++ G+ + + TI L+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 1640 KYKFLLFGIQ----------DGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDS 1689
Y+ L IQ D S + G+ +P +P VT+ T S
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 1690 LRLSWTVPEGQFDSFVVQFK---DKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLG 1746
+SW F V+++ + D PQ + + SV + L GRKY +Y +
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 1747 KKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSF 1806
+ + T A A PP P + + V S+ + W+ P+ +
Sbjct: 796 DGEQSLILSTSQTTAPDA--------PPDPTVDQ------VDDTSIVVRWSRPQAPITGY 841
Query: 1807 VVQYKDR-DGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGR 1865
+ Y +G + + + V++ L P +Y + +Y + + P+ T G
Sbjct: 842 RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT 901
Query: 1866 EETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWM-----VTEGEFDSFEIQYTDRDG 1920
++T P P +L E T + + W VT D + G
Sbjct: 902 PRSDT--------VPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
Query: 1921 QLQMVRIGGDRNDIT-LSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPT 1979
Q R+ RN ++GL Y ++ S G+ P LT + K P
Sbjct: 952 Q----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----LTAQQTTKLDAPTN 1002
Query: 1980 ATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAVRVPGHEE 2038
L + T ++ + WT P Q + L GQP+ V
Sbjct: 1003 -------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
Query: 2039 GVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLL 2098
+ L+P +Y ++L G Q + V T +P P P
Sbjct: 1050 KYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL---------QPGSSIP-----PYN 1095
Query: 2099 GELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2158
E+T T ++ ++WT P R F + + G V + + V GL PG +
Sbjct: 1096 TEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
Query: 2159 YKMHLYGLHEGR-RVGPVSAVGVTAPE-------EESPDAPLAKLRLGQMTVRDITSDSL 2210
Y + L +G+ R P+ VT E +PD + + + T DIT
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG--Y 1206
Query: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270
++ T GQ + L + + D + T L P +Y +++Y +
Sbjct: 1207 RITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 2271 VGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ- 2329
P+S + P P+L +L+ D T S+ L WT
Sbjct: 1256 SVPISDTII---------------------PEVPQLTDLSFVDITDSSIGLRWTPLNSST 1294
Query: 2330 -FDHFLVQYKNGDGQPKATRVPGHEDRV-------TISGLEPDNKYKMNLYGFHGGQRVG 2381
+ + G+G +P ED V T++GLEP Y +++ G
Sbjct: 1295 IIGYRITVVAAGEG------IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESA 1348
Query: 2382 PVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQG-RFDS 2440
P + TA P PT+ L T PD++ ++W P +
Sbjct: 1349 PTTLTQQTAV----PPPTD----------------LRFTNIGPDTMRVTWAPPPSIDLTN 1388
Query: 2441 FTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTA 2498
F V+Y V + ++ V + L PG +Y V V++
Sbjct: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY-----------------VVSVSS 1431
Query: 2499 PQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD 2558
E + TP T P + + + +S ++ W P+ + +++
Sbjct: 1432 VYEQHESTPLRGRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITGYRIRHHP 1485
Query: 2559 R--DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQ 2616
GRP+ RV + +T+ L PG +Y + + L+ GR P+ +G + T
Sbjct: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL-LIG----QQSTVS 1539
Query: 2617 AVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRV 2674
VP +L + ATP SL +SW P ++ + Y G+ + V
Sbjct: 1540 DVPR------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1587
Query: 2675 PGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPP 2734
PG + TISGL+P Y + +Y G G + A + P TE +P
Sbjct: 1588 PGSKSTATISGLKPGVDYTITVYAVTGR---------GDSPASSK-PISINYRTEIDKP- 1636
Query: 2735 EEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGR-PQVMRVRG-EESEVTVG 2792
++ VT +S+S+ W + V ++G P + G +++E+T+
Sbjct: 1637 -----SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
Query: 2793 GLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTD 2852
GL+P +Y + +Y + P+ VT N R L TD
Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLVQTAVT------------------NIDRPKGLAFTD 1733
Query: 2853 ATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVP-GHEDGVTISGLEPDHKYKMNL 2910
DS+ ++W P+GQ + V Y + DG ++ P G ED + GL P +Y +++
Sbjct: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
Query: 2911 YGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSW 2970
H P+ TA PAPT+ L T +P SLS W
Sbjct: 1794 VALHDDMESQPLIGTQSTAI----PAPTD----------------LKFTQVTPTSLSAQW 1833
Query: 2971 TIPQGRFDSFTVQY--KDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVG 3028
T P + + V+ K++ G + + + + S V V GL KY++ +Y L +
Sbjct: 1834 TPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR 1893
Query: 3029 PVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHF 3088
P V T PP + R VTDAT ++++SW F
Sbjct: 1894 PAQGVVTTLEN-------------VSPPRRAR-----VTDATETTITISWRTKTETITGF 1935
Query: 3089 LVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEE 3147
V +GQ R + TI+GL+P YK+ LY + R PV T +
Sbjct: 1936 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1995
Query: 3148 TPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQV 3207
PS L ++P+SL +SW P+ R + ++Y+ P+
Sbjct: 1996 APS------------------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
Query: 3208 V--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
V R R +E T+ GLEPG +Y +++ L Q+ P+ T LP
Sbjct: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
Score = 283 bits (725), Expect = 2e-75
Identities = 418/1893 (22%), Positives = 698/1893 (36%), Gaps = 312/1893 (16%)
Query: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEY---------- 816
+W P P + Y +++ P A +P ++Y +GL PG Y
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 817 ---QVTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
+VT TS P + T P V +T ++ + W+ V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 868 DRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
F V Y G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
G L +L T+ P P P + Q D+T + V W+
Sbjct: 796 DGEQSL-ILSTSQTTAPDAPPD------PTVDQ------------VDDTS-IVVRWSRPQ 835
Query: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE-NQESTPVV 893
Query: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104
Q ++ +S P +L + T + + WT PE + + D P
Sbjct: 894 IQ----QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPV 944
Query: 1105 VVPVEGPQR-------SAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
+P E QR A +T L PG Y F ++ + PL A Q
Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTKLD 998
Query: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY-RDRDGRPQVVPVEGPERSFVVSS 1216
P NL + T ++ + WT P Q + + R G+P+ V + + +
Sbjct: 999 APT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
Query: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
L P +Y +L I + T TT PP T VT +
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTETT 1102
Query: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR-GR 1335
+ ++WT A P F + + +QG V D + V GL P +Y + LR G+
Sbjct: 1103 IVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
Query: 1336 QRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSLSL 1390
+R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1161 ERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDITGY 1206
Query: 1391 FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1207 RIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYK- 1509
P+S T P P+L +L+ D+T +S+GL WT S I+ Y+
Sbjct: 1258 PIS--------------DTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRI 1300
Query: 1510 DKDGQPQVVPVAADQRE-----VTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLP 1564
+ +P+ D + TV LEP Y +++ L +G P ++ TA P
Sbjct: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP 1360
Query: 1565 PAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDGQPQV--V 1621
P +L T+I PD++ ++W P + +F+V+Y + V +
Sbjct: 1361 PT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1405
Query: 1622 PVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELW 1681
++ V + +L P +Y + + + +P+ KT G SP +
Sbjct: 1406 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG------ID 1456
Query: 1682 VTDPTPDSLRLSWTVPEGQFDSFVVQFKDK---DGPQVVPVEGHERSVTVTPLDAGRKYR 1738
+D T +S + W P + ++ + P+ V S+T+T L G +Y
Sbjct: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516
Query: 1739 FLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTV 1798
+ L G++ L +S + D PR +L+V T S+ +SW
Sbjct: 1517 VSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTSLLISWDA 1561
Query: 1799 PEGQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPI 1856
P + + Y + G Q V GS ++ GL P Y + +Y + G+ P
Sbjct: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPA 1620
Query: 1857 SAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT 1916
S+ I+ TE P+ ++ V + +++ + W+ + + + T
Sbjct: 1621 SSKPISI---NYRTEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
Query: 1917 DRD--GQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974
++ G + G D+ ++T+ GL+ Y+V++Y + P+ A+T + K
Sbjct: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
Query: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAVRV 2033
L TD DS+ ++W P+GQ + V Y + DG +
Sbjct: 1728 -----------------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
Query: 2034 P-GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEP 2092
P G E+ + GL P +Y +++ H P+ TA P+PT
Sbjct: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA----IPAPT--------- 1817
Query: 2093 AEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQVVRVGGEESEVTV 2150
+L T +P SLS WT P + + V+ K++ G + + + + S V V
Sbjct: 1818 -------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
Query: 2151 GGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSL 2210
GL KY++ +Y L + P V VT E SP + V D T ++
Sbjct: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSPPR--------RARVTDATETTI 1921
Query: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2269
++SW F V +GQ R + TI+GL+P YK+ LY +
Sbjct: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981
Query: 2270 RVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ 2329
R PV + AST P L TP+SL +SW P +
Sbjct: 1982 RSSPV-------------VIDASTAIDAP--------SNLRFLATTPNSLLVSWQPPRAR 2020
Query: 2330 FDHFLVQYKNGDGQPKATRVPGHEDRV---TISGLEPDNKYKMNLYGFHGGQRVGPVSAI 2386
++++Y+ G P VP V TI+GLEP +Y + + Q+ P+
Sbjct: 2021 ITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 2079
Query: 2387 GVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK 2446
T + + P++ PE + P + T + P + G T +
Sbjct: 2080 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-----GYDTGNGIQLPGTSGQQ 2134
Query: 2447 DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDET 2506
G+ + G P R ++ Y + G + +G P+EDVD
Sbjct: 2135 PSVGQQMIFEEHGFRRTTPPTTATPIR-HRPRPYPPNVGEEI----QIG-HIPREDVDYH 2188
Query: 2507 PSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD-SFTVQYKDRDGRPQA 2565
P PG + L + T+ SW Q + + D P
Sbjct: 2189 LYPHGPGLNPNASTGQEALSQTTI----------SWAPFQDTSEYIISCHPVGTDEEPLQ 2238
Query: 2566 VRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRR 2598
RV G + T+ GL G Y + + L + +R
Sbjct: 2239 FRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271
Score = 279 bits (714), Expect = 4e-74
Identities = 367/1692 (21%), Positives = 642/1692 (37%), Gaps = 303/1692 (17%)
Query: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181
G +Y+ YG +G+ PL Q+ PS P + + T P+S + W
Sbjct: 582 GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
Query: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237
P+ +++++R ++ GR + + G S+ + L P Y L I ++YG
Sbjct: 633 PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
Query: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290
T T+ P PL+ +VT +T S +SW A
Sbjct: 690 QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
Query: 1291 FMVQYK--DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348
F V+Y+ + +PQ + + V +P L P RKY +N+Y + G +S++ T+
Sbjct: 750 FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
Query: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408
T AP++P +P + ++ T S+ + W+ PQ + + Y
Sbjct: 807 Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
Query: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467
+G + + + VT+ L+PG +Y + +Y + E Q PV Q+ET
Sbjct: 848 SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
Query: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524
S P +L +VT V + WT PE + ++ Q +P++ +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583
EVT L P Y ++ + G+ PL+ A + +K L +
Sbjct: 961 FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
Query: 1584 TVTDITPDSVGLSWTVPEGEFDSF-VVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642
TD T V + WT P + + + R GQP+ V + + +L+P+ +Y
Sbjct: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
Query: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701
L I+ G + SP + T + +S PP + T+ T ++ ++WT P F
Sbjct: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
Query: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTT- 1759
V + + P+ V S+ V+ L G +Y + + L G++R P+ T
Sbjct: 1116 KLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
Query: 1760 ----------------------EARSAMDDTG---TKRPPKPRLGEEL-QVTTVTQNSVG 1793
E + D TG T P + G L +V Q+S
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query: 1794 LSWTVPEGQFDSFVVQYK-DRDGQP---QVVPVEGSLREVSVPGLDPAH---RYKLLLYG 1846
P +++ V K D++ P ++P L ++S + + R+ L
Sbjct: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS 1293
Query: 1847 LHHGKRVGPISA---------------------------------VAITAGREETETETT 1873
G R+ ++A + + G E T T
Sbjct: 1294 TIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT 1353
Query: 1874 APTPPAPEPHLGELTVEEATSHTLHLSWMVTEG-EFDSFEIQYT--DRDGQLQMVRIGGD 1930
T P +L T+ ++W + +F ++Y+ + + + I
Sbjct: 1354 QQTAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS 1410
Query: 1931 RNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRL 1990
N + L+ L Y+V++ + P+ ++ + PT
Sbjct: 1411 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR------GRQKTGLDSPTG---------- 1454
Query: 1991 GELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPD 2048
+ +D T +S ++ W P + +++ + G+P+ RVP +T++ L P
Sbjct: 1455 --IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1512
Query: 2049 HKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSP 2108
+Y VS+V + EE P + + + +L V ++P
Sbjct: 1513 TEY--------------VVSIVALNGREE------SPLLIGQQSTVSDVPRDLEVVAATP 1552
Query: 2109 DSLSLSWTVPQGRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYGL 2166
SL +SW P + + Y + G Q V G +S T+ GL+PG Y + +Y +
Sbjct: 1553 TSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1612
Query: 2167 HEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLV 2226
GR P S+ ++ D P QM V D+ +S+S+ W + V
Sbjct: 1613 -TGRGDSPASSKPISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRV 1665
Query: 2227 QF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGK 2284
KNG G K + +TI GL+P +Y +++Y + P+ +T +
Sbjct: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1725
Query: 2285 DEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKN-GDGQ 2343
+ +A TD DS+ ++W P+GQ + V Y + DG
Sbjct: 1726 PKGLA---------------------FTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGI 1764
Query: 2344 PKATRVP-GHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPS 2402
+ P G ED + GL P ++Y +++ H P+ TA P+PT
Sbjct: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA----IPAPT--- 1817
Query: 2403 MEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQVVRVGGE 2460
+L T +P SLS WT P + + V+ K++ G + + + +
Sbjct: 1818 -------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864
Query: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
S V V GL KY++ +Y L + P GV E+V PP
Sbjct: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV--------------SPP 1908
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVR-VGGQESKVTVRG 2579
VT ++ ++++SW F V +G+ R + T+ G
Sbjct: 1909 R-----RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
Query: 2580 LEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDA 2639
L+PG YK++LY L++ R PV +A T P+ L
Sbjct: 1964 LQPGTDYKIYLYTLNDNARSSPVVI------DASTAIDAPS------------NLRFLAT 2005
Query: 2640 TPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMNL 2696
TP+SL +SW P + ++++Y P+ V VP GV TI+GLEP +Y + +
Sbjct: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYV 2064
Query: 2697 YGFHGGQRVGPI 2708
Q+ P+
Sbjct: 2065 IALKNNQKSEPL 2076
Score = 269 bits (688), Expect = 4e-71
Identities = 403/1792 (22%), Positives = 669/1792 (37%), Gaps = 294/1792 (16%)
Query: 769 WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRAL-RGTS 827
W A V + +++ + EG P + +PS+A++ + L PG++Y V V +
Sbjct: 740 WVSASDTVSGFRVEYELSEEGDEPQYLD-LPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
Query: 828 WGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYV-SAGNQRVRLEV 886
L S + TT D P D V V T++ + W RPQA + + + Y S L +
Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
Query: 887 PPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPS 946
P A+ L+DL PGV+Y +T+ A S P ++ T +P + PS
Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP------RSDTVPS--- 909
Query: 947 TTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEE 1006
P++L + V T ++WT +++ + PG H +
Sbjct: 910 -------------PRDLQFVEVTDVKVT----IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
Query: 1007 VLPGDVRQ-ALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRL 1065
LP A V PG Y + V G + S P+ Q + K P L
Sbjct: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHG-RESKPLTAQ--------QTTKLDAPTNL 1003
Query: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK-DRDGQPQVVPVEGPQRSAVITSLDPGR 1124
+ TD T +L+RWT P + + + R GQP+ V + +L P
Sbjct: 1004 QFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
Query: 1125 KYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG 1184
+Y L G + + P PP+ T+ T ++ ++WT P
Sbjct: 1061 EYTVSLVAIKGNQESPKATG---VFTTLQPGSSIPPYN-----TEVTETTIVITWT-PAP 1111
Query: 1185 QFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN-KKRYGPLTADG 1243
+ F + R G V S VVS L P +Y +T+ + + ++R P+
Sbjct: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
Query: 1244 TTAPERKEEPPRPEFLE-QPLLGELTVT---GVTPD--SLRLSWTVAQGPFDSFMVQYKD 1297
T PP LE P G LTV+ TPD R++ T G
Sbjct: 1171 VTPLS----PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ---------- 1216
Query: 1298 AQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP 1357
QG V D++ T L P +Y +++Y ++ +D + P
Sbjct: 1217 -QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK-----------------DDKESVP 1258
Query: 1358 SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDR-----DGR 1412
+ PE P L +L+ + S+ L WT P S S + Y+ +G
Sbjct: 1259 ISDTI------IPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAGEGI 1309
Query: 1413 PRAVR-VGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATES 1471
P V TV GLEPG Y + + L G P T QQ PP T+
Sbjct: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTD- 1363
Query: 1472 PLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQYKDKDGQPQV--VPVAADQREVT 1528
L T++ P+++ ++W P +F+V+Y + V + ++ V
Sbjct: 1364 --------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1415
Query: 1529 VYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDI 1588
+ NL P +Y +++ +++ PL K L+ G + +DI
Sbjct: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLR--------------GRQKTGLDSPTG-IDFSDI 1460
Query: 1589 TPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAADQREVTIPDLEPSRKYKFLLF 1646
T +S + W P + +++ G+P+ V + +T+ +L P +Y +
Sbjct: 1461 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1520
Query: 1647 GIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706
+ +G+ SP+ + ++ PR +L V TP SL +SW P + +
Sbjct: 1521 AL-NGREESPLLIGQQSTVSD------VPR--DLEVVAATPTSLLISWDAPAVTVRYYRI 1571
Query: 1707 QFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARS 1763
+ + G V V G + + T++ L G Y +Y + G+ + + R+
Sbjct: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
Query: 1764 AMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQ-PQVVPV 1822
+D KP ++QVT V NS+ + W + V ++G P
Sbjct: 1632 EID--------KP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
Query: 1823 EG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPE 1881
G E+++ GL P Y + +Y + P+ A+T P
Sbjct: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT----------NIDRPKG-- 1728
Query: 1882 PHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD-RDGQLQMVRI-GGDRNDITLSGL 1939
L + ++ ++W +G+ + + Y+ DG ++ G+ + L GL
Sbjct: 1729 -----LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL 1783
Query: 1940 ESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDAT 1999
Y V++ D P+ TA P P +L T T
Sbjct: 1784 RPGSEYTVSVVALHDDMESQPLI------------GTQSTAIPAPT------DLKFTQVT 1825
Query: 2000 PDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYG 2057
P SLS WT P Q + V+ + G K + + V +SGL KY++++Y
Sbjct: 1826 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1885
Query: 2058 FHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTV 2117
P V VT E +P P A VT ++ ++++SW
Sbjct: 1886 LKDTLTSRPAQGV-VTTLENVSP---------PRRAR--------VTDATETTITISWRT 1927
Query: 2118 PQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2176
F V +G+ + R + + T+ GL+PG YK++LY L++ R PV
Sbjct: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
Query: 2177 AVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPK 2236
TA DAP + T +SL +SW P + ++++++ P+
Sbjct: 1988 IDASTA-----IDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
Query: 2237 AVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPAST 2293
V VP GV TI+GLEP +Y + + Q+ P L K +E+ T
Sbjct: 2037 EV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP-----LIGRKKTDELPQLVT 2090
Query: 2294 EPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQF-DHFLVQYKNGDGQPKATRVPGH 2352
P P L P+ L + TV + F H Y G+G ++PG
Sbjct: 2091 LP-------HPNLH-------GPEILDVPSTVQKTPFVTH--PGYDTGNG----IQLPG- 2129
Query: 2353 EDRVTISGLEPDNKYKMNLYGFHGGQR-VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEE 2411
SG +P +M ++ HG +R P +A + P ++ P E
Sbjct: 2130 -----TSGQQPSVGQQM-IFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183
Query: 2412 ----------PLLGELTVTGSSP-DSLSLSWTVPQGRFD-SFTVQYKDRDGRPQVVRVGG 2459
P L TG ++SW Q + + D P RV G
Sbjct: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPG 2243
Query: 2460 EESEVTVGGLEPGRKYKMHLYGLHEGRR---------VGPVSTVGVTAPQED 2502
+ T+ GL G Y + + L + +R VG G+ P +D
Sbjct: 2244 TSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDD 2295
Score = 211 bits (536), Expect = 2e-53
Identities = 337/1549 (21%), Positives = 567/1549 (36%), Gaps = 296/1549 (19%)
Query: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
Query: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
Query: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 919 PAS---VRANTGSS--PLGLLGT------TDEPPPS-----GPSTTQGAQAPLLQQRPQE 962
A+ GSS P T T P P G +QG +AP ++ +
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAP--REVTSD 1134
Query: 963 LGELRVLG--------------RD----------------------------ETGRLRVV 980
G + V G RD +TG L V
Sbjct: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
Query: 981 W--TAQPDTFAYFQLRMRVPEGP------GAHEEVLPGDVRQALVPPPPPGTPYELSLHG 1032
W + PD Y R+ P + EEV+ D PG Y +S++
Sbjct: 1195 WERSTTPDITGY-----RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 1033 VPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSF 1092
V K S PI I + P+L +L+ D T S+ LRWT S
Sbjct: 1250 V-KDDKESVPISDTIIPE-----------VPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
Query: 1093 VIQYK-----DRDGQPQVVP-VEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGP--LVA 1144
+I Y+ +G P V+ +T L+PG Y + + P L
Sbjct: 1295 IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ 1354
Query: 1145 EAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV- 1202
+ + P +D L T+ PD++ ++W P F+V+Y V
Sbjct: 1355 QTAVPPPTD-----------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
Query: 1203 -VPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQ 1261
+ + + + V+++L P +Y ++ + + PL T L+
Sbjct: 1404 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDS 1451
Query: 1262 PLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGL 1319
P + + +T +S + W + + +++ + G+P+ V N +T+ L
Sbjct: 1452 PT--GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1509
Query: 1320 DPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELT 1379
P +Y +++ L GR+ SP +G ++ S + +L
Sbjct: 1510 TPGTEYVVSIVALNGREE--------------------SPLLIGQQSTVS---DVPRDLE 1546
Query: 1380 VTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYK 1437
V ++P SL + W P + + + Y + G + V G +S T+ GL+PG Y
Sbjct: 1547 VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1606
Query: 1438 MHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVP 1497
+ +Y + G+ P S+ ++ + E + ++ VTDV NS+ + W
Sbjct: 1607 ITVYAV-TGRGDSPASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPS 1656
Query: 1498 EGQFDSFIVQYKDKD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLS 1555
+ V K+ G + DQ E+T+ L+P +Y +++Y +
Sbjct: 1657 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE----- 1711
Query: 1556 VVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-R 1614
+ PL T +P L TD+ DS+ ++W P+G+ + V Y
Sbjct: 1712 ----SQPLVQTAVTNIDRPK------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE 1761
Query: 1615 DGQPQVVPVAADQREVT--IPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPG 1672
DG ++ P A D E T + L P +Y + + D P+ T
Sbjct: 1762 DGIHELFP-APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--------- 1811
Query: 1673 APPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVT 1729
A P +L T TP SL WT P Q + V+ K+K GP + + + SV V+
Sbjct: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS 1871
Query: 1730 PLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQ 1789
L KY +Y L P A+ + PP+ +VT T+
Sbjct: 1872 GLMVATKYEVSVYALKDTLTSRP--------AQGVVTTLENVSPPR-----RARVTDATE 1918
Query: 1790 NSVGLSWTVPEGQFDSFVVQYKDRDGQ-PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLH 1848
++ +SW F V +GQ P ++ +R ++ GL P YK+ LY L+
Sbjct: 1919 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
Query: 1849 HGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEF 1908
R P+ A TA + A TP ++L +SW
Sbjct: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTP-----------------NSLLVSWQPPRARI 2021
Query: 1909 DSFEIQYTDRDGQLQMVRIGGDR---NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEA 1965
+ I+Y ++ G + R + T++GLE Y + + + + P+
Sbjct: 2022 TGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL---- 2076
Query: 1966 LTVPEEEKPSEPPTAT-PEPPIKPRLGELTVTDATPDSLSLSWTVPEGQF-DHFLVQYRN 2023
+ ++ P T P P + P+ L + TV + F H Y
Sbjct: 2077 --IGRKKTDELPQLVTLPHPNLH-----------GPEILDVPSTVQKTPFVTH--PGYDT 2121
Query: 2024 GDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPT 2083
G+G +++PG SG +P +M ++ HG +R P + TP
Sbjct: 2122 GNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTPPTTA--------TPIRH 2162
Query: 2084 EPSMEAPEPAEEPLLGELT-----------VTGSSPDS---------LSLSWTVPQGRFD 2123
P P EE +G + G +P++ ++SW Q +
Sbjct: 2163 RPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSE 2222
Query: 2124 -SFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRR 2171
+ D P RV G + T+ GL G Y + + L + +R
Sbjct: 2223 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271
Score = 206 bits (523), Expect = 5e-52
Identities = 291/1263 (23%), Positives = 464/1263 (36%), Gaps = 195/1263 (15%)
Query: 764 TVRTEWTPAPGPVDAYEIQFIPTT--EGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821
TV E + P + Y I PT +G S S+ +D L+PG EY V+V
Sbjct: 1192 TVSWERSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVY 1248
Query: 822 ALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAE-VDRFVVSYVSAGNQ 880
++ +P S TI + DL V +T +++ L W + + + ++ V+AG
Sbjct: 1249 TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
Query: 881 RVRLE--VPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG-SSPLGLLGTT 937
E V +T L PG++Y ++V N G S+P L T
Sbjct: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT------------LINGGESAPTTLTQQT 1356
Query: 938 DEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDT-FAYFQLRMR 996
PPP+ T +G D +RV W P F +R
Sbjct: 1357 AVPPPTDLRFTN-------------------IGPDT---MRVTWAPPPSIDLTNFLVRY- 1393
Query: 997 VPEGPGAHEEVLPGDVRQALVPPPP---------PGTPYELSLHGVPPGGKPSDPIIYQG 1047
P +EE DV + + P PGT Y +S+ V + S P+
Sbjct: 1394 ---SPVKNEE----DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPL---- 1441
Query: 1048 IMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDR--DGQPQV 1105
+ +K G S + +D T++S + W P + I++ G+P+
Sbjct: 1442 ---RGRQKTGLDSPTG----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1494
Query: 1106 VPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNL 1165
V + S +T+L PG +Y + G++ E+ +L + P +L
Sbjct: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-------ESPLLIGQQSTVSDVPR--DL 1545
Query: 1166 WVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV--VPVEGPERSFVVSSLDPDHKY 1223
V TP SL +SW P + + Y + G V V G + + +S L P Y
Sbjct: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605
Query: 1224 RFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTV 1283
T++ + + P ++ + R E +++P ++ VT V +S+ + W
Sbjct: 1606 TITVYAVTGRGD-SPASSKPISINYRTE-------IDKP--SQMQVTDVQDNSISVKWLP 1655
Query: 1284 AQGPFDSFMVQYKDAQGQ-PQAVPVAG-DENEVTVPGLDPDRKYKMNLYGLRGRQRVGPE 1341
+ P + V G P AG D+ E+T+ GL P +Y +++Y Q E
Sbjct: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA----QNPSGE 1711
Query: 1342 SVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDS 1401
S ++D L T DS+ + W PQG
Sbjct: 1712 SQPLVQTAVTNIDRPKG-------------------LAFTDVDVDSIKIAWESPQGQVSR 1752
Query: 1402 FTVQYKD-RDGRPRAVRV-GGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTA 1459
+ V Y DG G+E + GL PG +Y + + LH+ P+
Sbjct: 1753 YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG----- 1807
Query: 1460 PQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQY--KDKDGQPQV 1517
T+S P +L T VTP S+ WT P Q + V+ K+K G +
Sbjct: 1808 ---------TQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858
Query: 1518 VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLE 1577
+ +A D V V L KY++++Y L D P V+ T E PP
Sbjct: 1859 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--------ENVSPPRR 1910
Query: 1578 PRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVV-PVAADQREVTIPDLE 1636
R VTD T ++ +SW F V +GQ + + D R TI L+
Sbjct: 1911 AR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1965
Query: 1637 PSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTV 1696
P YK L+ + D R SPV ++A T AP L L TP+SL +SW
Sbjct: 1966 PGTDYKIYLYTLNDNARSSPVVIDASTAI------DAPSNLRFL---ATTPNSLLVSWQP 2016
Query: 1697 PEGQFDSFVVQFKDKDGP--QVVP-VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPL 1753
P + ++++++ P +VVP T+T L+ G +Y + L ++ PL
Sbjct: 2017 PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
Query: 1754 TADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDR 1813
T+ + T P E L V + Q + + G +Q
Sbjct: 2077 IGRKKTD---ELPQLVTLPHPNLHGPEILDVPSTVQKT---PFVTHPGYDTGNGIQLPGT 2130
Query: 1814 DGQ-----PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREET 1868
GQ Q++ E R + P R++ Y + G+ I G
Sbjct: 2131 SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEE--------IQIGHIPR 2182
Query: 1869 ETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD-SFEIQYTDRDGQLQMVRI 1927
E P P + T +EA S T +SW + + D + R+
Sbjct: 2183 EDVDYHLYPHGPGLNPNASTGQEALSQTT-ISWAPFQDTSEYIISCHPVGTDEEPLQFRV 2241
Query: 1928 GGDRNDITLSGLESDHRYLVTLYGFSDGKH---------VGPVHVEALTVPEEEKPSEPP 1978
G TL+GL Y + + D + VG E L P ++ +P
Sbjct: 2242 PGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPY 2301
Query: 1979 TAT 1981
T +
Sbjct: 2302 TVS 2304
Score = 103 bits (258), Expect = 3e-21
Identities = 103/429 (24%), Positives = 166/429 (38%), Gaps = 62/429 (14%)
Query: 740 YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
YA GE P ++ G+ ++ +++ W G V Y + + +G
Sbjct: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
Query: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
F A +A + +GL PG EY V+V AL P T +T I P DL+
Sbjct: 1764 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1822
Query: 850 AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
VTPT+L W P ++ R V+ + + P++ +++ LM +Y V+
Sbjct: 1823 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
Query: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
V A + S PA G++ T + P R
Sbjct: 1883 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1912
Query: 968 VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027
V ET + + W + +T FQ+ G + + DVR + PGT Y+
Sbjct: 1913 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
Query: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
+ L+ + + S P++ D P L L T +SLL+ W P
Sbjct: 1972 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 2019
Query: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
++I+Y ++ G P +VVP P A IT L+PG +Y + ++ PL+
Sbjct: 2020 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
Query: 1145 EAKI--LPQ 1151
K LPQ
Sbjct: 2079 RKKTDELPQ 2087
Score = 89.0 bits (219), Expect = 9e-17
Identities = 93/400 (23%), Positives = 144/400 (36%), Gaps = 67/400 (16%)
Query: 762 ETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821
ETT+ W + +++ +P P + +Y GL PG +Y++ +
Sbjct: 1918 ETTITISWRTKTETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
Query: 822 ALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGN-- 879
L + P +T ID P +LR +A TP +L + W P+A + +++ Y G+
Sbjct: 1976 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 2035
Query: 880 QRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSP--------- 930
+ V P +T L PG EY + V A + S P R T P
Sbjct: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 2095
Query: 931 ------LGLLGTTDEPP---PSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVW 981
L + T + P G T G Q P + +G+ + +E G R
Sbjct: 2096 LHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIF--EEHGFRR--- 2150
Query: 982 TAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSD 1041
T P T + R R P P EE+ G + P Y L HG PG
Sbjct: 2151 TTPPTTATPIRHRPR-PYPPNVGEEIQIGHI-------PREDVDYHLYPHG--PG----- 2195
Query: 1042 PIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK--DR 1099
P S+G L + T++ W P + ++I
Sbjct: 2196 ------------LNPNASTGQEALSQTTIS----------W-APFQDTSEYIISCHPVGT 2232
Query: 1100 DGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRH 1139
D +P V G SA +T L G Y ++ ++RH
Sbjct: 2233 DEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH 2272
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 327 bits (837), Expect = 2e-88
Identities = 399/1802 (22%), Positives = 691/1802 (38%), Gaps = 313/1802 (17%)
Query: 1378 LTVTGSSPDSLSLFWTVPQGS-FDSFTVQYKDRD--GRPRAVRVGGKESEVTVGGLEPGH 1434
+T T S P+S + W PQ S + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 1435 KYKMHL-----YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLG-ELTVTDVTPN 1488
Y+ L YG E R + + P T +P P + +VT++T +
Sbjct: 676 VYEGQLISIQQYGHQEVTRF-DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
Query: 1489 SVGLSWTVPEGQFDSFIVQYK--DKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGL- 1545
S +SW F V+Y+ ++ +PQ + + + V + +L P RKY +N+Y +
Sbjct: 735 SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
Query: 1546 HDGQRMGPLSVVIVTAP-LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
DG++ LS TAP PP P TV + S+ + W+ P+
Sbjct: 795 EDGEQSLILSTSQTTAPDAPPDP----------------TVDQVDDTSIVVRWSRPQAPI 838
Query: 1605 DSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKT 1663
+ + Y +G + + VT+ DL+P +Y ++ +++ + +PV ++ +T
Sbjct: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Query: 1664 VARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP----QVVPV 1719
+ PR +L + T + + WT PE + V + P Q +P+
Sbjct: 899 TGTPRSDTVPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 1720 EGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLG 1779
VT L G Y F ++ + + PLTA TT+ D T
Sbjct: 957 -SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-----DAPT--------- 1001
Query: 1780 EELQVTTVTQNSVGLSWTVPEGQFDSF-VVQYKDRDGQPQVVPVEGSLREVSVPGLDPAH 1838
LQ T ++V + WT P Q + + R GQP+ V S+ + + L PA
Sbjct: 1002 -NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
Query: 1839 RYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLH 1898
Y +S VAI G +E+ T T P + E T T+
Sbjct: 1061 EY--------------TVSLVAI-KGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIV 1104
Query: 1899 LSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV 1958
++W T F++ G + D I +SGL Y+ T+ DG+
Sbjct: 1105 ITW--TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ-- 1160
Query: 1959 GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT---DATPD--SLSLSWTVPEGQ 2013
+A V + P PPT P G LTV+ TPD ++ T GQ
Sbjct: 1161 ---ERDAPIVNKVVTPLSPPT-NLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
Query: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073
+ L + + D + T L P +Y +++Y + P+S +
Sbjct: 1217 QGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP 1265
Query: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQG-RFDSFTVQYKDR 2132
A P PT +L T PD++ ++W P +F V+Y
Sbjct: 1266 A----VPPPT----------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 2133 DGRPQV--VRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDA 2190
V + + ++ V + L PG +Y + + ++E P + ++ D+
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-----LRGRQKTGLDS 1360
Query: 2191 PLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQF--KNGDGQPKAVRVPGHEDGVT 2248
P + DIT++S ++ W P + ++ ++ G+P+ RVP + +T
Sbjct: 1361 PTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
Query: 2249 ISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEE 2308
++ L P +Y +++ +G + +P + + S P +
Sbjct: 1415 LTNLTPGTEYVVSIVALNGREE----------SPLLIGQQSTVSDVP-----------RD 1453
Query: 2309 LTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNK 2366
L V ATP SL +SW P ++ + Y G+ + VPG + TISGL+P
Sbjct: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
Query: 2367 YKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP-SMEAPEPPEEPLLGELTVTGSSPD 2425
Y + +Y G ++P+ ++P S+ ++P ++ VT +
Sbjct: 1514 YTITVYAVTG---------------RGDSPASSKPISINYRTEIDKP--SQMQVTDVQDN 1556
Query: 2426 SLSLSWTVPQGRFDSF--TVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLH 2483
S+S+ W + T K+ G + G +++E+T+ GL+P +Y + +Y +
Sbjct: 1557 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1616
Query: 2484 EGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWT 2543
P+ VT ++D L T DS+ ++W
Sbjct: 1617 PSGESQPLVQTAVT----NIDRPKG-------------------LAFTDVDVDSIKIAWE 1653
Query: 2544 VPQGRFDSFTVQYKD-RDGRPQAVRV-GGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGP 2601
PQG+ + V Y DG + G+E ++GL PG +Y + + LH+ P
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
Query: 2602 VSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQ 2661
+ T A+P T +L T TP SLS WT P Q + V+
Sbjct: 1714 LIGTQST--------AIPAPT----------DLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
Query: 2662 Y--RNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEE 2719
+ G K + + V +SGL KY++++Y P + VT E
Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENV 1814
Query: 2720 TPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQV 2779
+P T+A E ++++SW F V +G+ +
Sbjct: 1815 SPPRRARVTDATE-----------------TTITISWRTKTETITGFQVDAVPANGQTPI 1857
Query: 2780 MR-VRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPE 2838
R ++ + T+ GL+PG YK++LY L++ R PV +A T P+
Sbjct: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI------DASTAIDAPS---- 1907
Query: 2839 PPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGV--- 2895
L TP+SL +SW P + ++++Y P+ V VP GV
Sbjct: 1908 --------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEA 1958
Query: 2896 TISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT--EPSTEAPEPPEEPLL 2953
TI+GLEP +Y + + Q+ P+ IG +E T P+ PE + P
Sbjct: 1959 TITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELPQLVTLPHPNLHGPEILDVPST 2016
Query: 2954 GELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCK 3013
+ T + P Y +G +++ G G +P
Sbjct: 2017 VQKTPFVTHPG-------------------YDTGNG----IQLPG------TSGQQPSVG 2047
Query: 3014 YKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDS 3073
+M ++ H +R P T A P P P +G+ ++ T
Sbjct: 2048 QQM-IFEEHGFRRTTP--------------PTTATPIRHRPRPYPPNVGQEALSQTT--- 2089
Query: 3074 LSLSWMVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGG 3132
+SW + ++ + + G D +P RVPG T++GL Y + +
Sbjct: 2090 --ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQ 2147
Query: 3133 QR 3134
QR
Sbjct: 2148 QR 2149
Score = 311 bits (798), Expect = 7e-84
Identities = 336/1513 (22%), Positives = 595/1513 (39%), Gaps = 190/1513 (12%)
Query: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584
+T T S P+S + W PQ + ++++ ++ GR + + G + T++GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641
Y+ L + + G + V+ T T T+T E P P + ++T+ T
Sbjct: 676 VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Query: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698
S +SW F V+Y GD +P+ + +P V I L P KY +N+Y
Sbjct: 734 SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
Query: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758
G S+I T+ T AP+ P +P + ++ T S+ + W+
Sbjct: 793 I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
Query: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
PQ + + Y +G + + + VT+ L+PG +Y + +Y + E + PV
Sbjct: 834 PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
Query: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872
Q T TP P +L + T +++ W PE + D
Sbjct: 893 ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
Query: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931
V GQ R+P ++GL P Y ++ G+ P++ T +
Sbjct: 943 PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
Query: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990
APT L + ++ + WT P+ + + + R G+
Sbjct: 999 ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050
P+ V S+ + L+P +Y VS V + ++ + T T
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
Query: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110
+ P I P E+T T ++ ++W P + F + R G V
Sbjct: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
Query: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167
+ +SGL P +Y + GQ R P+ V + TP PT EA P
Sbjct: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
Query: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224
G LTV+ ++PD T T + G V ++S T L P
Sbjct: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
Query: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
G +Y + +Y + + + P+S T +P P +L + D++ ++W
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
Query: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
+FLV+Y + + + +S AV ++ L P +Y + + P+
Sbjct: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
Query: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399
+T D+ + +D T +S + W P + +++ + GR + V
Sbjct: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459
++ +T+ L P +Y + L+GR+ + +T ++P +L V T
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
Query: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517
+SL +SW + + Y +T G + V + T T+ L+PG Y +Y
Sbjct: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
Query: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577
+ G D+PA E + + VTD +S+ + W +
Sbjct: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
Query: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635
P + V NG P G DQ+++ I GL+P+ Y +Y + PL
Sbjct: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
Query: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695
T + RP+ L+ TDV S+++ WE+P G + + + P
Sbjct: 1626 QTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIH 1674
Query: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755
E P P G +A L+ LR G+ Y++++ L ++ + GT T P
Sbjct: 1675 ELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--- 1723
Query: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLI 3814
+P DL+F+++ TS W PP + ++V + P + + + + + + GL+
Sbjct: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
Query: 3815 PGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQNPVDT 3872
+YEV+V +++ S P G +TT+ + P + R + TE + W+ +
Sbjct: 1784 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITG 1843
Query: 3873 YDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 3931
+ V V A G P+Q Y + L T+Y + L +SP I +T +
Sbjct: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
Query: 3932 EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQLLGL 3989
+AP +L TP + L++W P R GY++ + PG +E++ G+T + GL
Sbjct: 1904 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1963
Query: 3990 FPSTSYNARLQAM 4002
P T Y + A+
Sbjct: 1964 EPGTEYTIYVIAL 1976
Score = 311 bits (796), Expect = 1e-83
Identities = 411/1857 (22%), Positives = 694/1857 (37%), Gaps = 338/1857 (18%)
Query: 1433 GHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGL 1492
G +Y+ + YG +G Q +T P++ P+E + E T PNS +
Sbjct: 582 GVRYQCYCYG----------RGIGEWHCQPLQTYPSSSGPVEVFITE---TPSQPNSHPI 628
Query: 1493 SWTVPE-GQFDSFIVQYKDKD--GQPQVVPVAADQREVTVYNLEPERKYK-----MNMYG 1544
W P+ +I++++ K+ G+ + + T+ L+P Y+ + YG
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYG 688
Query: 1545 LHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
+ R + + P+ T + P +VT+IT S +SW
Sbjct: 689 HQEVTRFD-FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1605 DSFVVQYK--DRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAK 1662
F V+Y+ + +PQ + + + V IPDL P RKY ++ I + +S + ++
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1663 TVARGDASPGAPPRLGELWVTDPTPD-----SLRLSWTVPEGQFDSF-VVQFKDKDGPQV 1716
T A P APP DPT D S+ + W+ P+ + +V +G
Sbjct: 808 TTA-----PDAPP--------DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 1717 -VPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRP-- 1773
+ + SVT++ L G +Y +Y + + P+ T TGT R
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET--------TGTPRSDT 906
Query: 1774 -PKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLRE---- 1828
P PR +LQ VT V + WT PE + V D P +P E R
Sbjct: 907 VPSPR---DLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPVNLPGEHGQRLPISR 958
Query: 1829 ---VSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLG 1885
V GL P Y ++ + HG+ P++A + T+ APT
Sbjct: 959 NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA--------QQTTKLDAPT--------- 1001
Query: 1886 ELTVEEATSHTLHLSWMVTEGEFDSFEIQY-TDRDGQLQMVRIGGDRNDITLSGLESDHR 1944
L T T+ + W + + + R GQ + +G + L L+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
Query: 1945 YLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLS 2004
Y V+L G P T T P I P E+T T ++
Sbjct: 1062 YTVSLVAIK-GNQESPKATGVFT-----------TLQPGSSIPPYNTEVTET-----TIV 1104
Query: 2005 LSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQ-R 2063
++WT P + F + R G V + +SGL P +Y + GQ R
Sbjct: 1105 ITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 2064 MGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVT---GSSPDSLSLSWTVPQG 2120
P+ VT PT +EA P G LTV+ ++PD T
Sbjct: 1163 DAPIVNKVVTPLSP----PTNLHLEA-----NPDTGVLTVSWERSTTPDITGYRIT---- 1209
Query: 2121 RFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGV 2180
T + G V ++S T L PG +Y + +Y + + + P+S +
Sbjct: 1210 -----TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII 1264
Query: 2181 TAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEG-QFDHFLVQFK--NGDGQPKA 2237
A P LR +I D++ ++W P +FLV++ +
Sbjct: 1265 PAVP------PPTDLRF-----TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
Query: 2238 VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPT 2297
+ + ++ V ++ L P +Y +++ + P+ G G D PT
Sbjct: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR--GRQKTGLDS---------PT 1362
Query: 2298 PEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDR 2355
+ +D T +S ++ W P + +++ ++ G+P+ RVP +
Sbjct: 1363 G----------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 2356 VTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLG 2415
+T++ L P +Y +++ +G EE+P + P +
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNG---------------REESPLLIGQQSTVSDVPRD---- 1453
Query: 2416 ELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGR 2473
L V ++P SL +SW P + + Y + G V V G +S T+ GL+PG
Sbjct: 1454 -LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGV 1512
Query: 2474 KYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGS 2533
Y + +Y + GR P S+ ++ + PS ++ VT
Sbjct: 1513 DYTITVYAV-TGRGDSPASSKPISINYRTEIDKPS------------------QMQVTDV 1553
Query: 2534 SPDSLSLSWTVPQGRFDSF--TVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLY 2591
+S+S+ W + T K+ G + G ++++T+ GL+P +Y + +Y
Sbjct: 1554 QDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613
Query: 2592 GLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVP 2651
+ P+ VT + R L TD DS+ ++W P
Sbjct: 1614 AQNPSGESQPLVQTAVTNID------------------RPKGLAFTDVDVDSIKIAWESP 1655
Query: 2652 EGQFDHFLVQYRNG-DGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPIS 2709
+GQ + V Y + DG + P G ED + GL P +Y +++ H P+
Sbjct: 1656 QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI 1715
Query: 2710 VIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQ 2769
TA P+PT+L T +P SLS WT P + V+
Sbjct: 1716 GTQSTAI----PAPTDLK----------------FTQVTPTSLSAQWTPPNVQLTGYRVR 1755
Query: 2770 Y--KDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAE 2827
K++ G + + + + S V V GL KY++ +Y L + P V T +
Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1815
Query: 2828 TTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVR 2887
PP + R VTDAT ++++SW F V +GQ + R
Sbjct: 1816 -----------PPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1859
Query: 2888 -VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPE 2946
+ TI+GL+P YK+ LY + R P+ + TA + AP+
Sbjct: 1860 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID----APSN------- 1908
Query: 2947 PPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVV--RVRGEESEVT 3004
L ++P+SL +SW P+ R + ++Y+ P+ V R R +E T
Sbjct: 1909 ---------LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1959
Query: 3005 VGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGEL 3064
+ GLEPG +Y +++ L Q+ P+ + T +P + P P L
Sbjct: 1960 ITGLEPGTEYTIYVIALKNNQKSEPLIG---------RKKTDELPQLVTLP--HPNLHGP 2008
Query: 3065 TVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKM 3124
+ D ++ G Y G+G +++PG SG +P +M
Sbjct: 2009 EILDVPSTVQKTPFVTHPG--------YDTGNG----IQLPG------TSGQQPSVGQQM 2050
Query: 3125 NLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSW 3184
++ HG +R P + TP P P +E L ++SW
Sbjct: 2051 -IFEEHGFRRTTPPTT------ATPIRHRPRPYPPNVGQEAL-----------SQTTISW 2092
Query: 3185 TVPQGRFD-SFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR 3240
Q + + D +P RV G + T+ GL G Y + + L + QR
Sbjct: 2093 APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2149
Score = 310 bits (795), Expect = 1e-83
Identities = 399/1797 (22%), Positives = 682/1797 (37%), Gaps = 301/1797 (16%)
Query: 2080 PSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRP 2136
P T PS P +T T S P+S + W PQ + ++++ ++ GR
Sbjct: 601 PLQTYPSSSGPVEVF------ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRW 654
Query: 2137 QVVRVGGEESEVTVGGLEPGRKYKMHL-----YGLHEGRRVG--------PVSAVGVTAP 2183
+ + G + T+ GL+PG Y+ L YG E R PV++ VT
Sbjct: 655 KEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTG- 713
Query: 2184 EEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFK---NGDGQPKAVRV 2240
E +P +PL +V +IT+ S +SW F V+++ GD +P+ + +
Sbjct: 714 -ETTPFSPLVAT---SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDL 768
Query: 2241 PGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEP 2300
P V I L P KY +N+Y +S G ++ + ++++ P+
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVY---------QISEDG------EQSLILSTSQTTAPDA 813
Query: 2301 PIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTIS 2359
P P ++++ T S+ + W+ P+ + + Y +G +P + VT+S
Sbjct: 814 PPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
Query: 2360 GLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTV 2419
L+P +Y + +Y Q PV +E T +P ++ +P + + ++ V
Sbjct: 869 DLQPGVQYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKV 923
Query: 2420 TGSSPDSLSLSWTVPQG-----RFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2474
T + WT P+ R D V G+ + + V GL PG
Sbjct: 924 T--------IMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTGLSPGVT 972
Query: 2475 YKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSS 2534
Y ++ + GR P+ TA Q + P+ L +
Sbjct: 973 YYFKVFAVSHGRESKPL-----TAQQTTKLDAPT------------------NLQFVNET 1009
Query: 2535 PDSLSLSWTVPQGRFDSFTVQYK-DRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGL 2593
++ + WT P+ + + + R G+P+ VG SK +R L+P +Y + L
Sbjct: 1010 DSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLV-- 1067
Query: 2594 HEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG 2653
A+ ++ + T T+ P I P E+T T ++ ++WT P
Sbjct: 1068 ----------AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTET-----TIVITWT-PAP 1111
Query: 2654 QFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIG 2712
+ F + R G V + +SGL P +Y + GQ R PI
Sbjct: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI---- 1166
Query: 2713 VTAAEEETPSPTELSTEAPEPPEEPLLGELTVT---GSSPDSLSLSWTIPQGHFDSFTVQ 2769
V PT L EA P G LTV+ ++PD T T
Sbjct: 1167 VNKVVTPLSPPTNLHLEA-----NPDTGVLTVSWERSTTPDITGYRIT---------TTP 1212
Query: 2770 YKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETT 2829
+ G V ++S T L PG +Y + +Y + + + P+S +
Sbjct: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP------- 1265
Query: 2830 QAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-QFDHFLVQYRNGDGQPKVVR- 2887
AVP T +L T+ PD++ ++W P +FLV+Y + V
Sbjct: 1266 -AVPPPT----------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1314
Query: 2888 -VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPE 2946
+ ++ V ++ L P +Y +SV V E TP T
Sbjct: 1315 SISPSDNAVVLTNLLPGTEYV--------------VSVSSVYEQHESTPLRGRQKTGLDS 1360
Query: 2947 PPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDR--DGRPQVVRVRGEESEVT 3004
P + + + +S ++ W P+ + +++ GRP+ RV + +T
Sbjct: 1361 PTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
Query: 3005 VGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGEL 3064
+ L PG +Y + + L+ G+ P+ +G + T VP +L
Sbjct: 1415 LTNLTPGTEYVVSIVALN-GREESPL-LIG------QQSTVSDVPR------------DL 1454
Query: 3065 TVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDGVTISGLEPDHKY 3122
V ATP SL +SW P ++ + Y G+ + VPG + TISGL+P Y
Sbjct: 1455 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
Query: 3123 KMNLYGFHGGQRVGPVSAIGVTEEETPSPTEP-STEAPEAPEEPLLGELTVTGSSPDSLS 3181
+ +Y G ++P+ ++P S ++P ++ VT +S+S
Sbjct: 1515 TITVYAVTG-------------RGDSPASSKPISINYRTEIDKP--SQMQVTDVQDNSIS 1559
Query: 3182 LSWTVPQGRFDSFTVQYKDRDGQ-PQVVRVRG-EESEVTVGGLEPGRKYKMHLYGLHEGQ 3239
+ W + V ++G P + G +++E+T+ GL+P +Y + +Y +
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
Query: 3240 RVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQ- 3298
P+ +T R LA V DS+ ++W QG + V Y +
Sbjct: 1620 ESQPLVQTAVTNI--------DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
Query: 3299 GQPQAVPV-SGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLG 3357
G + P G+ + GL P +Y + L + P+ TA P+P
Sbjct: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI---PAPT-- 1726
Query: 3358 ELTVTDATPDSVGLSWTVPEGEFDSFVVQY--KDKDGRLQVVPVAANQREVTVQGLEPSR 3415
+L T TP S+ WT P + + V+ K+K G ++ + +A + V V GL +
Sbjct: 1727 DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1786
Query: 3416 KYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFD 3475
KY +Y L P TT LE PP +T A ET+ + +SW
Sbjct: 1787 KYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDATETT--ITISWRTKTETIT 1842
Query: 3476 SFVVQYRDTDGQ-PRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTA 3534
F V +GQ P + D R+ T+ L+PG YK LY L R PV TA
Sbjct: 1843 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
Query: 3535 PEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQ 3594
+ + LA TTP+S+ +SW + ++++YE
Sbjct: 1903 IDAPSNLRFLA-------------------TTPNSLLVSWQPPRARITGYIIKYEKPGSP 1943
Query: 3595 PQALLVDGDQ--SKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEES 3652
P+ ++ ++ I+GLEP T Y + L ++ PL T P Q
Sbjct: 1944 PREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP--QLVTLP 2001
Query: 3653 RPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGT 3712
P L + DV ++ + + PG +D+ G+ P T P Q G
Sbjct: 2002 HPNLHGPEILDVPSTVQKTPFVTHPG-YDT---GNGIQLPGTSGQQPSVGQQMIFEEHGF 2057
Query: 3713 RHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRE--TSA 3770
R + T +P+ PR + +E +
Sbjct: 2058 RRTT-----------------------------PPTTATPIRHRPRPYPPNVGQEALSQT 2088
Query: 3771 KVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVR 3827
++W P ++ + + EP +V G + + L GL GA Y + V +++
Sbjct: 2089 TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK 2145
Score = 303 bits (775), Expect = 3e-81
Identities = 362/1616 (22%), Positives = 610/1616 (37%), Gaps = 283/1616 (17%)
Query: 1683 TDPTPDSLRLSWTVPE-GQFDSFVVQFKDKDGP---QVVPVEGHERSVTVTPLDAGRKYR 1738
T P+S + W P+ ++++++ K+ + + GH S T+ L G Y
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
Query: 1739 FLLYGLLGKKRHGPLTADGTTEARS----AMDDTGTKRPPKPRLGEELQVTTVTQNSVGL 1794
L + D TT + S + TG P P + VT +T +S +
Sbjct: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
Query: 1795 SWTVPEGQFDSFVVQYK--DRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKR 1852
SW F V+Y+ + +PQ + + + V++P L P +Y + +Y +
Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-- 796
Query: 1853 VGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFE 1912
G S + T+ +TTAP P P+P TV++ ++ + W + +
Sbjct: 797 -GEQSLILSTS-------QTTAPDAP-PDP-----TVDQVDDTSIVVRWSRPQAPITGYR 842
Query: 1913 IQYTDR-DGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEE 1971
I Y+ +G + + N +TLS L+ +Y +T+Y + + PV ++ T
Sbjct: 843 IVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---- 898
Query: 1972 EKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV 2031
T TP P +L + T +++ WT PE + V D P V
Sbjct: 899 -------TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIP--V 944
Query: 2032 RVPG-HEEGVTIS--------GLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSP 2082
+PG H + + IS GL P Y ++ G+ P++ T + T
Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--- 1001
Query: 2083 TEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK-DRDGRPQVVRV 2141
L + ++ + WT P+ + + + R G+P+ V
Sbjct: 1002 -----------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
Query: 2142 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMT 2201
G S+ + L+P +Y + L + +G + P A GV + P
Sbjct: 1045 GPSVSKYPLRNLQPASEYTVSLVAI-KGNQESP-KATGVFTTLQPGSSIPPYNT------ 1096
Query: 2202 VRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 2261
++T ++ ++WT P + F + + G V + +SGL P +Y
Sbjct: 1097 --EVTETTIVITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
Query: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTP-EPPIKPRLEELTVTDATPDS-- 2318
+ GQ E AP + TP PP LE A PD+
Sbjct: 1153 IQVLRDGQ----------------ERDAPIVNKVVTPLSPPTNLHLE------ANPDTGV 1190
Query: 2319 LSLSW---TVPEGQFDHFLVQYKNGD-GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
L++SW T P+ NG G V + T L P +Y +++Y
Sbjct: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
Query: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434
+ P+S + A P PT+ L T PD++ ++W P
Sbjct: 1251 KDDKESVPISDTIIPAV----PPPTD----------------LRFTNIGPDTMRVTWAPP 1290
Query: 2435 QG-RFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPV 2491
+F V+Y V + ++ V + L PG +Y
Sbjct: 1291 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---------------- 1334
Query: 2492 STVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2551
V V++ E + TP T P + + + +S ++ W P+
Sbjct: 1335 -VVSVSSVYEQHESTPLRGRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITG 1387
Query: 2552 FTVQYKDR--DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTE 2609
+ +++ GRP+ RV + +T+ L PG +Y + + L+ GR P+ +G
Sbjct: 1388 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL-LIG--- 1442
Query: 2610 DEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDG 2667
+ T VP +L + ATP SL +SW P ++ + Y G+
Sbjct: 1443 -QQSTVSDVPR------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489
Query: 2668 QPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELS 2727
+ VPG + TISGL+P Y + +Y G G + A + P
Sbjct: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR---------GDSPASSK-PISINYR 1539
Query: 2728 TEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGR-PQVMRVRG-E 2785
TE +P ++ VT +S+S+ W + V ++G P + G +
Sbjct: 1540 TEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
Query: 2786 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRL 2845
++E+T+ GL+P +Y + +Y + P+ VT N R
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT------------------NIDRP 1635
Query: 2846 GELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVP-GHEDGVTISGLEPD 2903
L TD DS+ ++W P+GQ + V Y + DG ++ P G ED + GL P
Sbjct: 1636 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1695
Query: 2904 HKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSP 2963
+Y +++ H P+ TA PAPT+ L T +P
Sbjct: 1696 SEYTVSVVALHDDMESQPLIGTQSTAI----PAPTD----------------LKFTQVTP 1735
Query: 2964 DSLSLSWTIPQGRFDSFTVQY--KDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGL 3021
SLS WT P + + V+ K++ G + + + + S V V GL KY++ +Y L
Sbjct: 1736 TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1795
Query: 3022 HEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVP 3081
+ P V T PP + R VTDAT ++++SW
Sbjct: 1796 KDTLTSRPAQGVVTTLEN-------------VSPPRRAR-----VTDATETTITISWRTK 1837
Query: 3082 EGQFDHFLVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSA 3140
F V +GQ R + TI+GL+P YK+ LY + R PV
Sbjct: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
Query: 3141 IGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD 3200
T + PS L ++P+SL +SW P+ R + ++Y+
Sbjct: 1898 DASTAIDAPS------------------NLRFLATTPNSLLVSWQPPRARITGYIIKYEK 1939
Query: 3201 RDGQPQVV--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
P+ V R R +E T+ GLEPG +Y +++ L Q+ P+ T LP
Sbjct: 1940 PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995
Score = 290 bits (743), Expect = 2e-77
Identities = 386/1760 (21%), Positives = 652/1760 (37%), Gaps = 290/1760 (16%)
Query: 2208 DSLSLSWTVPE-GQFDHFLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2264
+S + W P+ +++++ KN G+ K +PGH + TI GL+P Y+ L
Sbjct: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
Query: 2265 F--HGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLS 2322
+G Q V T + T TP P+ E +VT+ T S +S
Sbjct: 684 IQQYGHQEVTRFDFT--TTSTSTPVTSNTVTGETTPFSPLVATSE--SVTEITASSFVVS 739
Query: 2323 WTVPEGQFDHFLVQYK---NGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
W F V+Y+ GD +P+ +P V I L P KY +N+Y
Sbjct: 740 WVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVY------- 791
Query: 2380 VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD 2439
+S G + T T AP+ P +P + ++ T S+ + W+ PQ
Sbjct: 792 --QISEDGEQSLILSTSQTT-----APDAPPDPTVDQVDDT-----SIVVRWSRPQAPIT 839
Query: 2440 SFTVQYKDR-DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTA 2498
+ + Y +G + + + VT+ L+PG +Y + +Y + E + PV T
Sbjct: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Query: 2499 PQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG-----RFDSFT 2553
D PSP + L + +++ WT P+ R D
Sbjct: 900 GTPRSDTVPSPRD----------------LQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
Query: 2554 VQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAE 2613
V G+ + + + V GL PG Y ++ + GR P++A T+ +A
Sbjct: 944 VNLPGEHGQRLPI---SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
Query: 2614 TTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAV 2672
T L + T ++ + WT P Q + L GQP+
Sbjct: 1001 TN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 2673 RVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTEL-STEAP 2731
V + L+P +Y ++L G Q E+P T + +T P
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQ---------------ESPKATGVFTTLQP 1087
Query: 2732 EPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTV 2791
P E+T T ++ ++WT P F + + G V + + V
Sbjct: 1088 GSSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 2792 GGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPN-----KPRLG 2846
GL PG +Y + L +G+ E +A V T P N P G
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQ-----------ERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
Query: 2847 ELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLE 2901
LTV+ TPD ++ GQ + L + + D + T L
Sbjct: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLS 1238
Query: 2902 PDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGS 2961
P +Y +++Y + PIS +T P P PP + L T
Sbjct: 1239 PGLEYNVSVYTVKDDKESVPIS---------DTIIPAVP------PPTD-----LRFTNI 1278
Query: 2962 SPDSLSLSWTIPQG-RFDSFTVQYKDRDGRPQVVR--VRGEESEVTVGGLEPGCKYKMHL 3018
PD++ ++W P +F V+Y V + ++ V + L PG +Y + +
Sbjct: 1279 GPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1338
Query: 3019 YGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSW 3078
++E P+ + +T PT + +D T +S ++ W
Sbjct: 1339 SSVYEQHESTPL--------RGRQKTGLDSPT------------GIDFSDITANSFTVHW 1378
Query: 3079 MVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVG 3136
+ P + +++ + G+P+ RVP + +T++ L P +Y +++ +G
Sbjct: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1433
Query: 3137 PVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 3196
EE+P + + P + L V ++P SL +SW P + +
Sbjct: 1434 --------REESPLLIGQQSTVSDVPRD-----LEVVAATPTSLLISWDAPAVTVRYYRI 1480
Query: 3197 QYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Y + G V V G +S T+ GL+PG Y + +Y + G+ P S+ I+
Sbjct: 1481 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYR 1539
Query: 3255 TPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ-PQAVPVSG-DLRA 3312
T + + ++ V V +S+ + W + P + V G P +G D
Sbjct: 1540 TEID---KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
Query: 3313 VAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLS 3372
+ + GL P +Y ++ P+ A T D R L TD DS+ ++
Sbjct: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNID-----RPKGLAFTDVDVDSIKIA 1651
Query: 3373 WTVPEGEFDSFVVQYKD-KDGRLQVVPVAANQREVT-VQGLEPSRKYRFLLYGLSGRKRL 3430
W P+G+ + V Y +DG ++ P + + +QGL P +Y + L
Sbjct: 1652 WESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES 1711
Query: 3431 GPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQY--RDTDGQP 3488
P+ +TA P +L + T +SL WT + V+ ++ G
Sbjct: 1712 QPLIGTQSTAI------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1765
Query: 3489 RAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEA 3548
+ + +A D +V V L KY+ +Y L P + T E
Sbjct: 1766 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL------------EN 1813
Query: 3549 PEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDGDQSKI 3607
PP R VTD T ++ +SW F V NGQ P + D
Sbjct: 1814 VSPPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
Query: 3608 LISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL-APAGQTSEESRPRLSQLSVTDVTT 3666
I+GL+P T Y+ LY L++ R P+ + +T + AP S L T
Sbjct: 1869 TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP------------SNLRFLATTP 1916
Query: 3667 SSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTL 3726
+SL ++W+ P +++++ P E PRP PG A + L GT
Sbjct: 1917 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR-------PGVTE-ATITGLEPGTE 1968
Query: 3727 YSLTLYGLRGPHKADSIQGTART--LSPVLESPR-DLQFSEIRETSAKVNWMPPPSRADS 3783
Y++ + L+ K++ + G +T L ++ P +L EI + + V P +
Sbjct: 1969 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-- 2026
Query: 3784 FKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVP 3843
Y +G +Q+ G + Q G + + GF + P T T +
Sbjct: 2027 ---GYDTGNG-----IQLPGTSGQQPSVG-------QQMIFEEHGFRRTTPPTT-ATPIR 2070
Query: 3844 DGPTQL------RALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAP--PLQAETPGSAVD 3895
P AL+ T + W P Q+ + Y + G PLQ PG++
Sbjct: 2071 HRPRPYPPNVGQEALSQT----TISWAPFQDTSE-YIISCHPVGTDEEPLQFRVPGTSTS 2125
Query: 3896 YPLHDLVLHTNYTATVRGLR 3915
L L Y V L+
Sbjct: 2126 ATLTGLTRGATYNIIVEALK 2145
Score = 277 bits (708), Expect = 2e-73
Identities = 328/1543 (21%), Positives = 584/1543 (37%), Gaps = 211/1543 (13%)
Query: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Y+ L YG E R +T + P T T P PL+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Query: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
Query: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Query: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
Query: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
Query: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
T+ +A T L + T ++ + W P Q + L
Sbjct: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
Query: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
Query: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
Query: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
Query: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
L P +Y +++Y + P+S + P PT+ L T
Sbjct: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA--VPPPTD----------------LRFT 1276
Query: 3174 GSSPDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKM 3230
PD++ ++W P +F V+Y + V + ++ V + L PG +Y +
Sbjct: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
Query: 3231 HLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSF 3290
+ ++E P+ T L +P ++ + +T++S + W + +
Sbjct: 1337 SVSSVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGY 1388
Query: 3291 LVQYRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAP 3348
+++ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV 1447
Query: 3349 DTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREV 3406
P +L V ATP S+ +SW P + + Y + G +Q V ++
Sbjct: 1448 SDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
Query: 3407 TVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLS 3466
T+ GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ +
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
Query: 3467 WTVAQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRL 3524
W + P + V ++ G + DQ +T+E L+P +Y
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV------------ 1609
Query: 3525 GPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSF 3584
VS E P + A + P+ L TD DS++++W QG +
Sbjct: 1610 --VSVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRY 1662
Query: 3585 VVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL 3642
V Y L DG++ + GL P + Y + LH+ PL +T +
Sbjct: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
Query: 3643 APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPL 3702
P + L T VT +SL W P + +R + P +
Sbjct: 1723 -----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTG 1763
Query: 3703 LQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQF 3762
+E+ + S V+ L T Y +++Y L+ + QG TL V PR +
Sbjct: 1764 PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARV 1822
Query: 3763 SEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVT 3822
++ ET+ ++W F+V A+G P + R+ + GL PG Y++
Sbjct: 1823 TDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
Query: 3823 VVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGA 3882
+ ++ S P+ +T D P+ LR L T ++ W+PP+ + Y ++ PG+
Sbjct: 1883 LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1942
Query: 3883 PPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 3922
PP + PG + + L T YT V L+ + P
Sbjct: 1943 PPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
Score = 264 bits (675), Expect = 1e-69
Identities = 383/1746 (21%), Positives = 664/1746 (38%), Gaps = 263/1746 (15%)
Query: 2309 LTVTDATPDSLSLSWTVPE-GQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDN 2365
+T T + P+S + W P+ +++++ KN G+ K +PGH + TI GL+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2366 KYKMNLYGF--HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGEL-TVTGS 2422
Y+ L +G Q V + T TP T ++ P PL+ +VT
Sbjct: 676 VYEGQLISIQQYGHQEV---TRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEI 731
Query: 2423 SPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
+ S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
Query: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
+ ED +++ + T AP P +P + ++ T S+ +
Sbjct: 792 QI-----------------SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-----SIVV 829
Query: 2541 SWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRL 2599
W+ PQ + + Y +G + + + VT+ L+PG +Y + +Y + E +
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 2600 GPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG-----Q 2654
PV Q T TP P +L + T +++ WT PE +
Sbjct: 890 TPV-----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYR 938
Query: 2655 FDHFLVQYRNGDGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGV 2713
D V GQ R+P ++GL P Y ++ G+ P++
Sbjct: 939 VDVIPVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
Query: 2714 TAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYK-D 2772
T + T L + ++ + WT P+ + +
Sbjct: 995 TKLDAPT--------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2773 RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAV 2832
R G+P+ V S+ + L+P +Y + L + +G + P +T GV T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKAT-GVF------TTLQ 1086
Query: 2833 PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHE 2892
P ++ P N T+ T ++ ++W P + F + R G V
Sbjct: 1087 PGSSIPPYN---------TEVTETTIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
Query: 2893 DGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEP 2951
+ +SGL P +Y + GQ R PI V PT EA P
Sbjct: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NP 1186
Query: 2952 LLGELTVT---GSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGL 3008
G LTV+ ++PD T T + G V ++S T L
Sbjct: 1187 DTGVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
Query: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068
PG +Y + +Y + KD+ E+ T+ P P +L T+
Sbjct: 1238 SPGLEYNVSVYTV-----------------KDDKESVPISDTIIPAVPPPT---DLRFTN 1277
Query: 3069 ATPDSLSLSWMVPEG-QFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 3125
PD++ ++W P +FLV+Y + + + ++ V ++ L P +Y ++
Sbjct: 1278 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
Query: 3126 LYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWT 3185
VS++ E TP T ++P ++T +S ++ W
Sbjct: 1338 ------------VSSVYEQHESTPLRGRQKTGL-DSPTGIDFSDITA-----NSFTVHWI 1379
Query: 3186 VPQGRFDSFTVQYKDR--DGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR--- 3240
P+ + +++ G+P+ RV + +T+ L PG +Y + + L+ +
Sbjct: 1380 APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
Query: 3241 -VGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQG 3299
+G STV PR +L V A T S+ +SW + + Y + G
Sbjct: 1440 LIGQQSTVSDV----------PR--DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1487
Query: 3300 QP--QAVPVSGDLRAVAVSGLDPARKYKFLLFGL----QNGKRHGPVPVEARTAPDTKPS 3353
Q V G +SGL P Y ++ + + P+ + RT D KPS
Sbjct: 1488 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPS 1546
Query: 3354 PRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQGL 3411
++ VTD +S+ + W + V K+G + +Q E+T++GL
Sbjct: 1547 ----QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602
Query: 3412 EPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQ 3471
+P+ +Y +Y + P+ TA + P L V + S++++W Q
Sbjct: 1603 QPTVEYVVSVYAQNPSGESQPLVQ---TAVTNIDRPKGLAFTDVDVD---SIKIAWESPQ 1656
Query: 3472 GPFDSFVVQYRDT-DGQPRAVPVA-ADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSA 3529
G + V Y DG P ++ T ++ L PG +Y + L P+
Sbjct: 1657 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
Query: 3530 LGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQY- 3588
TA P P + L T TP S+ W+ + V+
Sbjct: 1717 TQSTA-------------IPAPTD------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVT 1757
Query: 3589 -EDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQ 3647
++ G + + + D S +++SGL +T Y +Y L + P TT
Sbjct: 1758 PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT------- 1810
Query: 3648 TSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQREL 3707
S PR ++ VTD T +++ ++W F + VP+ + + +QR +
Sbjct: 1811 LENVSPPRRAR--VTDATETTITISWRTKTETITGFQVD-AVPA------NGQTPIQRTI 1861
Query: 3708 MVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRE 3767
P R S + L+ GT Y + LY L ++ + A T +++P +L+F
Sbjct: 1862 K-PDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST---AIDAPSNLRFLATTP 1916
Query: 3768 TSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK--LQGLIPGARYEVTVVS 3825
S V+W PP +R + + Y+ G P+ V + + + GL PG Y + V++
Sbjct: 1917 NSLLVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
Query: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQ--VTAPGAP 3883
++ ++SEPL G T D QL +T LH + T VT PG
Sbjct: 1976 LKNNQKSEPLIGRKKT--DELPQL----VTLPHPNLHGPEILDVPSTVQKTPFVTHPGYD 2029
Query: 3884 PLQA-ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEV 3942
+ PG++ P + G R T P + T P +
Sbjct: 2030 TGNGIQLPGTSGQQP----SVGQQMIFEEHGFR--RTTPPTTATPIRHRPRPYPPNVGQE 2083
Query: 3943 TPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGITSHQLLGLFPSTSYNARL 3999
++W P + Y++S H P G ++E L +PG TS L GL +YN +
Sbjct: 2084 ALSQTTISWA-PFQDTSEYIISCH-PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2141
Query: 4000 QAMWGQ 4005
+A+ Q
Sbjct: 2142 EALKDQ 2147
Score = 248 bits (633), Expect = 9e-65
Identities = 392/1803 (21%), Positives = 661/1803 (36%), Gaps = 326/1803 (18%)
Query: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ--------- 817
+W P P + Y +++ P A +P ++Y +GL PG Y+
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 818 ----VTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
VT TS P + T P V +T ++ + W+ V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 868 DRFVVSYVSA--GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
F V Y + G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
G L +L T+ P P Q D+T + V W+
Sbjct: 796 DGEQSL-ILSTSQTTAPDAPPDPTVDQV------------------DDTS-IVVRWSRPQ 835
Query: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QESTPVV 893
Query: 1045 YQGIMDKDEEKPG--KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102
Q +E G +S P +L + T + + WT PE + + D
Sbjct: 894 IQ------QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVI 942
Query: 1103 PQVVPVEGPQRSAV-------ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPS 1155
P +P E QR + +T L PG Y F ++ + PL A Q
Sbjct: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTK 996
Query: 1156 PGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-DRDGRPQVVPVEGPERSFVV 1214
P NL + T ++ + WT P Q + + R G+P+ V + +
Sbjct: 997 LDAPT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
Query: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
+L P +Y +L I + T TT PP T VT
Sbjct: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTE 1100
Query: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR- 1333
++ ++WT A P F + + +QG V D + V GL P +Y + LR
Sbjct: 1101 TTIVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
Query: 1334 GRQRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSL 1388
G++R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1159 GQERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDIT 1204
Query: 1389 SLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1205 GYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQ 1507
P+S + A PP T+ L T++ P+++ ++W P +F+V+
Sbjct: 1256 SVPISDTIIPA-----VPPPTD---------LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Query: 1508 YKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565
Y + V + ++ V + NL P +Y +++ +++ PL
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR---------- 1351
Query: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPV 1623
K L+ G + +DIT +S + W P + +++ G+P+ V
Sbjct: 1352 ----GRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 1624 AADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVT 1683
+ +T+ +L P +Y + + +G+ SP+ + ++ PR +L V
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD------VPR--DLEVV 1457
Query: 1684 DPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFL 1740
TP SL +SW P + + + + G V V G + + T++ L G Y
Sbjct: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
Query: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800
+Y + G+ + + R+ +D KP ++QVT V NS+ + W
Sbjct: 1518 VYAVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSS 1566
Query: 1801 GQFDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISA 1858
+ V ++G P G E+++ GL P Y + +Y + P+
Sbjct: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
Query: 1859 VAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD- 1917
A+T P L + ++ ++W +G+ + + Y+
Sbjct: 1627 TAVT----------NIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
Query: 1918 RDGQLQMVRI-GGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976
DG ++ G+ + L GL Y V++ D P+
Sbjct: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI------------GT 1717
Query: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVP 2034
TA P P +L T TP SLS WT P Q + V+ + G K + +
Sbjct: 1718 QSTAIPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771
Query: 2035 GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAE 2094
V +SGL KY++++Y P V VT E +P P A
Sbjct: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP---------PRRAR 1821
Query: 2095 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGL 2153
VT ++ ++++SW F V +G+ + R + + T+ GL
Sbjct: 1822 --------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
Query: 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLS 2213
+PG YK++LY L++ R PV TA DAP + T +SL +S
Sbjct: 1874 QPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLATTPNSLLVS 1922
Query: 2214 WTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQR 2270
W P + ++++++ P+ V VP GV TI+GLEP +Y + + Q+
Sbjct: 1923 WQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
Query: 2271 VGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQF 2330
P L K +E+ T P P L P+ L + TV + F
Sbjct: 1982 SEP-----LIGRKKTDELPQLVTLP-------HPNLH-------GPEILDVPSTVQKTPF 2022
Query: 2331 -DHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVT 2389
H Y G+G ++PG SG +P +M ++ HG +R P
Sbjct: 2023 VTH--PGYDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTP------- 2062
Query: 2390 AAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD-SFTVQYKDR 2448
P+ P P P P +G+ ++ ++SW Q + +
Sbjct: 2063 ------PTTATPIRHRPR-PYPPNVGQEALS-----QTTISWAPFQDTSEYIISCHPVGT 2110
Query: 2449 DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRR---------VGPVSTVGVTAP 2499
D P RV G + T+ GL G Y + + L + +R VG G+ P
Sbjct: 2111 DEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQP 2170
Query: 2500 QED 2502
+D
Sbjct: 2171 TDD 2173
Score = 226 bits (575), Expect = 5e-58
Identities = 321/1455 (22%), Positives = 541/1455 (37%), Gaps = 262/1455 (18%)
Query: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
Query: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
Query: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 919 PAS---VRANTGSS--PLGLLGT------TDEPPPS-----GPSTTQGAQAPLLQQRPQE 962
A+ GSS P T T P P G +QG +AP ++ +
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAP--REVTSD 1134
Query: 963 LGELRVLG--------------RD----------------------------ETGRLRVV 980
G + V G RD +TG L V
Sbjct: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
Query: 981 W--TAQPDTFAYFQLRMRVPEGP------GAHEEVLPGDVRQALVPPPPPGTPYELSLHG 1032
W + PD Y R+ P + EEV+ D PG Y +S++
Sbjct: 1195 WERSTTPDITGY-----RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 1033 VPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG-EFDS 1091
V K S PI D P + PP +L T+ D++ + W P + +
Sbjct: 1250 V-KDDKESVPI-------SDTIIP--AVPPPT--DLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Query: 1092 FVIQYKDRDGQPQV--VPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKIL 1149
F+++Y + V + + + V+T+L PG +Y + + PL K
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
Query: 1150 PQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDR--DGRPQVVPVEG 1207
S + +D T +S + W P + +++ GRP+ V
Sbjct: 1358 LDSPT---------GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
Query: 1208 PERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267
S +++L P +Y ++ + ++ L +T + PR +L
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV----SDVPR----------DL 1454
Query: 1268 TVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQP--QAVPVAGDENEVTVPGLDPDRKY 1325
V TP SL +SW + + Y + G Q V G ++ T+ GL P Y
Sbjct: 1455 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
Query: 1326 KMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSP 1385
+ +Y + GR S + ++D+ PS ++ VT
Sbjct: 1515 TITVYAVTGRGDSPASSKPISINYRTEIDK-PS------------------QMQVTDVQD 1555
Query: 1386 DSLSLFWTVPQGSFDSF--TVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGL 1443
+S+S+ W + T K+ G + G ++E+T+ GL+P +Y + +Y
Sbjct: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
Query: 1444 HEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDS 1503
+ P+ VT + + L TDV +S+ ++W P+GQ
Sbjct: 1616 NPSGESQPLVQTAVTNIDRPK--------------GLAFTDVDVDSIKIAWESPQGQVSR 1661
Query: 1504 FIVQYKD-KDGQPQVVPVAADQREVT--VYNLEPERKYKMNMYGLHDGQRMGPLSVVIVT 1560
+ V Y +DG ++ P A D E T + L P +Y +++ LHD PL T
Sbjct: 1662 YRVTYSSPEDGIHELFP-APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1720
Query: 1561 APLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQP 1618
A PAP +L T +TP S+ WT P + + V+ K++ G
Sbjct: 1721 A--IPAPT-------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1765
Query: 1619 QVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLG 1678
+ + +A D V + L + KY+ ++ ++D P T+ +PPR
Sbjct: 1766 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN-----VSPPRRA 1820
Query: 1679 ELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRK 1736
VTD T ++ +SW F V +G P ++ RS T+T L G
Sbjct: 1821 R--VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1878
Query: 1737 YRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW 1796
Y+ LY L R P+ D +T A+D L+ T NS+ +SW
Sbjct: 1879 YKIYLYTLNDNARSSPVVIDAST----AID-----------APSNLRFLATTPNSLLVSW 1923
Query: 1797 TVPEGQFDSFVVQYKDRDGQP--QVVP-VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRV 1853
P + ++++Y ++ G P +VVP + E ++ GL+P Y + + L + ++
Sbjct: 1924 QPPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
Query: 1854 GPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEI 1913
P+ GR++T+ T P P H E+ T+ + VT +D+
Sbjct: 1983 EPL------IGRKKTDELPQLVTLPHPNLHGPEIL---DVPSTVQKTPFVTHPGYDT--- 2030
Query: 1914 QYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEK 1973
+Q+ G + + + +H + +
Sbjct: 2031 -----GNGIQLPGTSGQQPSVGQQMIFEEHGF--------------------------RR 2059
Query: 1974 PSEPPTATP----EPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQP 2028
+ P TATP P P +G+ ++ T +SW + ++ + + G D +P
Sbjct: 2060 TTPPTTATPIRHRPRPYPPNVGQEALSQTT-----ISWAPFQDTSEYIISCHPVGTDEEP 2114
Query: 2029 KAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQR---MGPVSVVGVTAAEEETPSPTEP 2085
RVPG T++GL Y + + QR V VG + E PT+
Sbjct: 2115 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG-NSVNEGLNQPTDD 2173
Query: 2086 SMEAPEPAEEPLLGE 2100
S P +G+
Sbjct: 2174 SCFDPYTVSHYAVGD 2188
Score = 211 bits (537), Expect = 1e-53
Identities = 317/1504 (21%), Positives = 546/1504 (36%), Gaps = 268/1504 (17%)
Query: 760 LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819
+++T++ W+ P+ Y I + P+ EG+S +P +A++ L PG +Y +T
Sbjct: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTEL--NLPETANSVTLSDLQPGVQYNIT 879
Query: 820 VRA-----------LRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVD 868
+ A ++ + G P S T+ + P+DL+ V VT + + W P++ V
Sbjct: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPS----PRDLQFVEVTDVKVTIMWTPPESAVT 935
Query: 869 RFVVSYVSA---GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
+ V + G RL + +T L PGV Y V A S P + +
Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAE-VTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
Query: 926 T---GSSPLGLLGTTDE-------PPPS----------------------GPSTTQGAQA 953
T + L + TD PP + GPS ++
Sbjct: 995 TKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
Query: 954 PLL---------------QQRPQELGELRVLG--------RDETGRLRVVWTAQPDTFAY 990
L Q+ P+ G L E +V T P
Sbjct: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIG 1114
Query: 991 FQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMD 1050
F+L +R +G A EV D +V PG Y ++ + G + PI+ + +
Sbjct: 1115 FKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
Query: 1051 KDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYKDRDGQPQVVPVE 1109
P G LTV+ S T P+ + + G V
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTNGQQGNSLEEVVH 1226
Query: 1110 GPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTD 1169
Q S +L PG +Y +Y K P+ P PP +L T+
Sbjct: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPAVPPPT-DLRFTN 1277
Query: 1170 PTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVVSSLDPDHKYRFT 1226
PD++ ++W P F+V+Y V + + + + V+++L P +Y +
Sbjct: 1278 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
Query: 1227 LFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQG 1286
+ + + PL T L+ P + + +T +S + W +
Sbjct: 1338 VSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITANSFTVHWIAPRA 1383
Query: 1287 PFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVV 1344
+ +++ + G+P+ V N +T+ L P +Y +++ L GR+
Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE------- 1436
Query: 1345 AKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTV 1404
SP +G ++ S + +L V ++P SL + W P + + +
Sbjct: 1437 -------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISWDAPAVTVRYYRI 1480
Query: 1405 QYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQ 1462
Y + G + V G +S T+ GL+PG Y + +Y + G+ P S+ ++ +
Sbjct: 1481 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYR 1539
Query: 1463 EETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKD--GQPQVVPV 1520
E + ++ VTDV NS+ + W + V K+ G +
Sbjct: 1540 TEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
Query: 1521 AADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRL 1580
DQ E+T+ L+P +Y +++Y + + PL T +P
Sbjct: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---------SQPLVQTAVTNIDRPK----- 1636
Query: 1581 GELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQREVT--IPDLEP 1637
L TD+ DS+ ++W P+G+ + V Y DG ++ P A D E T + L P
Sbjct: 1637 -GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP-APDGEEDTAELQGLRP 1694
Query: 1638 SRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVP 1697
+Y + + D P+ T A P +L T TP SL WT P
Sbjct: 1695 GSEYTVSVVALHDDMESQPLIGTQST---------AIPAPTDLKFTQVTPTSLSAQWTPP 1745
Query: 1698 EGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLT 1754
Q + V+ K+K GP + + + SV V+ L KY +Y L P
Sbjct: 1746 NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP-- 1803
Query: 1755 ADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRD 1814
A+ + PP+ +VT T+ ++ +SW F V +
Sbjct: 1804 ------AQGVVTTLENVSPPR-----RARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
Query: 1815 GQ-PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETT 1873
GQ P ++ +R ++ GL P YK+ LY L+ R P+ A TA +
Sbjct: 1853 GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFL 1912
Query: 1874 APTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDR-- 1931
A TP ++L +SW + I+Y ++ G + R
Sbjct: 1913 ATTP-----------------NSLLVSWQPPRARITGYIIKY-EKPGSPPREVVPRPRPG 1954
Query: 1932 -NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTAT-PEPPIKPR 1989
+ T++GLE Y + + + + P+ + ++ P T P P +
Sbjct: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPL------IGRKKTDELPQLVTLPHPNLH-- 2006
Query: 1990 LGELTVTDATPDSLSLSWTVPEGQF-DHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPD 2048
P+ L + TV + F H Y G+G +++PG SG +P
Sbjct: 2007 ---------GPEILDVPSTVQKTPFVTH--PGYDTGNG----IQLPG------TSGQQPS 2045
Query: 2049 HKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSP 2108
+M ++ HG +R P + TP P P +E L
Sbjct: 2046 VGQQM-IFEEHGFRRTTPPTTA--------TPIRHRPRPYPPNVGQEAL----------- 2085
Query: 2109 DSLSLSWTVPQGRFD-SFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLH 2167
++SW Q + + D P RV G + T+ GL G Y + + L
Sbjct: 2086 SQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK 2145
Query: 2168 EGRR 2171
+ +R
Sbjct: 2146 DQQR 2149
Score = 111 bits (278), Expect = 1e-23
Identities = 140/616 (22%), Positives = 223/616 (36%), Gaps = 97/616 (15%)
Query: 740 YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
YA GE P ++ G+ ++ +++ W G V Y + + +G
Sbjct: 1613 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1672
Query: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
F A +A + +GL PG EY V+V AL P T +T I P DL+
Sbjct: 1673 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
Query: 850 AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
VTPT+L W P ++ R V+ + + P++ +++ LM +Y V+
Sbjct: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
Query: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
V A + S PA G++ T + P R
Sbjct: 1792 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1821
Query: 968 VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027
V ET + + W + +T FQ+ G + + DVR + PGT Y+
Sbjct: 1822 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
Query: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
+ L+ + + S P++ D P L L T +SLL+ W P
Sbjct: 1881 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 1928
Query: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
++I+Y ++ G P +VVP P A IT L+PG +Y + ++ PL+
Sbjct: 1929 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1987
Query: 1145 EAKI--LPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV 1202
K LPQ P H P+ L + TV + F T D Q+
Sbjct: 1988 RKKTDELPQLVTLPHPNLH---------GPEILDVPSTVQKTPFVTH--PGYDTGNGIQL 2036
Query: 1203 VPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQP 1262
G + S + +H +R T T T P R P P + Q
Sbjct: 2037 PGTSGQQPSVGQQMIFEEHGFRRT-------------TPPTTATPIRHRPRPYPPNVGQE 2083
Query: 1263 LLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVPGLDP 1321
L + T+ SW Q + + + +P V G T+ GL
Sbjct: 2084 ALSQTTI----------SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 2133
Query: 1322 DRKYKMNLYGLRGRQR 1337
Y + + L+ +QR
Sbjct: 2134 GATYNIIVEALKDQQR 2149
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 313 bits (801), Expect = 3e-84
Identities = 345/1553 (22%), Positives = 607/1553 (39%), Gaps = 191/1553 (12%)
Query: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584
+T T S P+S + W PQ + ++++ ++ GR + + G + T++GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641
Y+ L + + G + V+ T T T+T E P P + ++T+ T
Sbjct: 676 VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Query: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698
S +SW F V+Y GD +P+ + +P V I L P KY +N+Y
Sbjct: 734 SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
Query: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758
G S+I T+ T AP+ P +P + ++ T S+ + W+
Sbjct: 793 I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
Query: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
PQ + + Y +G + + + VT+ L+PG +Y + +Y + E + PV
Sbjct: 834 PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
Query: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872
Q T TP P +L + T +++ W PE + D
Sbjct: 893 ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
Query: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931
V GQ R+P ++GL P Y ++ G+ P++ T +
Sbjct: 943 PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
Query: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990
APT L + ++ + WT P+ + + + R G+
Sbjct: 999 ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050
P+ V S+ + L+P +Y VS V + ++ + T T
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
Query: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110
+ P I P E+T T ++ ++W P + F + R G V
Sbjct: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
Query: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167
+ +SGL P +Y + GQ R P+ V + TP PT EA P
Sbjct: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
Query: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224
G LTV+ ++PD T T + G V ++S T L P
Sbjct: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
Query: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
G +Y + +Y + + + P+S T +P P +L + D++ ++W
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
Query: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
+FLV+Y + + + +S AV ++ L P +Y + + P+
Sbjct: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
Query: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399
+T D+ + +D T +S + W P + +++ + GR + V
Sbjct: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459
++ +T+ L P +Y + L+GR+ + +T ++P +L V T
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
Query: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517
+SL +SW + + Y +T G + V + T T+ L+PG Y +Y
Sbjct: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
Query: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577
+ G D+PA E + + VTD +S+ + W +
Sbjct: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
Query: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635
P + V NG P G DQ+++ I GL+P+ Y +Y + PL
Sbjct: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
Query: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695
T + RP+ L+ TDV S+++ WE+P G + + + P
Sbjct: 1626 QTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIH 1674
Query: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755
E P P G +A L+ LR G+ Y++++ L ++ + GT T P
Sbjct: 1675 ELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--- 1723
Query: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLI 3814
+P DL+F+++ TS W PP + ++V + P + + + + + + GL+
Sbjct: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
Query: 3815 PGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQNPVDT 3872
+YEV+V +++ S P G +TT+ + P + R + TE + W+ +
Sbjct: 1784 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITG 1843
Query: 3873 YDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 3931
+ V V A G P+Q Y + L T+Y + L +SP I +T +
Sbjct: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
Query: 3932 EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQLLGL 3989
+AP +L TP + L++W P R GY++ + PG +E++ G+T + GL
Sbjct: 1904 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1963
Query: 3990 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 4042
P T Y + A+ P+ T + PF G + NG TS
Sbjct: 1964 EPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2015
Score = 287 bits (735), Expect = 1e-76
Identities = 378/1726 (21%), Positives = 647/1726 (37%), Gaps = 291/1726 (16%)
Query: 1267 LTVTGVTPDSLRLSWTVAQ-GPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDR 1323
+T T P+S + W Q +++++ K++ G+ + + G N T+ GL P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 1324 KYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPES-PEEPLLGEL-TVT 1381
Y+ L + Q+ G + V T T +P T E+ P PL+ +VT
Sbjct: 676 VYEGQLISI---QQYGHQEV---TRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 1382 GSSPDSLSLFWTVPQGSFDSFTVQYK--DRDGRPRAVRVGGKESEVTVGGLEPGHKYKMH 1439
+ S + W + F V+Y+ + P+ + + + V + L PG KY ++
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 1440 LYGLHE-GQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPE 1498
+Y + E G++ +S TAP ++P +P TV V S+ + W+ P+
Sbjct: 790 VYQISEDGEQSLILSTSQTTAP---------DAPPDP-----TVDQVDDTSIVVRWSRPQ 835
Query: 1499 GQFDSFIVQYKDK-DGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVV 1557
+ + Y +G + + VT+ +L+P +Y + +Y + + Q P+ +
Sbjct: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
Query: 1558 IVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSF---VVQYKDR 1614
T P + + + +L ++T V + WT PE + V+
Sbjct: 896 QETTGTPRSDTVPSPR--------DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
Query: 1615 DGQPQVVPVAADQ-REVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGA 1673
Q +P++ + EVT L P Y F +F + G+ P++ + T A
Sbjct: 948 GEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DA 999
Query: 1674 PPRLGELWVTDPTPDSLRLSWTVPEGQFDSF--VVQFKDKDGPQVVPVEGHERSVTVTPL 1731
P L + TD T + + WT P Q + V + P+ V + L
Sbjct: 1000 PTNLQFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
Query: 1732 DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNS 1791
+Y L + G + T TT G+ PP T VT+ +
Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTL------QPGSSIPPYN--------TEVTETT 1102
Query: 1792 VGLSWT-VPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHG 1850
+ ++WT P F V + + +V GS + V GL P Y + L G
Sbjct: 1103 IVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGS---IVVSGLTPGVEYVYTIQVLRDG 1159
Query: 1851 K-RVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD 1909
+ R PI +T T A P G LTV S T +
Sbjct: 1160 QERDAPIVNKVVTPLSPPTNLHLEA------NPDTGVLTVSWERS---------TTPDIT 1204
Query: 1910 SFEIQYTDRDGQ----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEA 1965
+ I T +GQ L+ V + D++ T L Y V++Y D K E+
Sbjct: 1205 GYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDK-------ES 1256
Query: 1966 LTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEG-QFDHFLVQYR-- 2022
+ + + P+ PP +L T+ PD++ ++W P +FLV+Y
Sbjct: 1257 VPISDTIIPAVPPPT-----------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 2023 NGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSP 2082
+ + + + V ++ L P +Y VSV V E TP
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYV--------------VSVSSVYEQHESTPLR 1351
Query: 2083 TEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR--DGRPQVVR 2140
P + + + +S ++ W P+ + +++ GRP+ R
Sbjct: 1352 GRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDR 1405
Query: 2141 VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQM 2200
V + +T+ L PG +Y + + L+ GR P+ + + D P +
Sbjct: 1406 VPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL----LIGQQSTVSDVPR------DL 1454
Query: 2201 TVRDITSDSLSLSWTVPEGQFDHFLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKY 2258
V T SL +SW P ++ + + G+ + VPG + TISGL+P Y
Sbjct: 1455 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
Query: 2259 KMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDS 2318
+ +Y G + P S+ ++ + E P+ ++ VTD +S
Sbjct: 1515 TITVYAVTG-RGDSPASSKPISINYRTEIDKPS----------------QMQVTDVQDNS 1557
Query: 2319 LSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHG 2376
+S+ W + V KNG G K + +TI GL+P +Y +++Y +
Sbjct: 1558 ISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1617
Query: 2377 GQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQG 2436
P+ VT +++ P+ L T DS+ ++W PQG
Sbjct: 1618 SGESQPLVQTAVT------------NIDRPK--------GLAFTDVDVDSIKIAWESPQG 1657
Query: 2437 RFDSFTVQYKD-RDGRPQVVRV-GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2494
+ + V Y DG ++ GEE + GL PG +Y TV
Sbjct: 1658 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY-----------------TV 1700
Query: 2495 GVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 2554
V A +D++ P T P P +L T +P SLS WT P + + V
Sbjct: 1701 SVVALHDDMESQPLIGTQSTAIPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRV 1754
Query: 2555 QY--KDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEA 2612
+ K++ G + + + S V V GL KY++ +Y L + P V T +
Sbjct: 1755 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1814
Query: 2613 ETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV 2672
PP + R +TDAT ++++SW F V +GQ
Sbjct: 1815 -----------SPPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1858
Query: 2673 R-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAP 2731
R + TI+GL+P YK+ LY + R P+ + TA +AP
Sbjct: 1859 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAP 1906
Query: 2732 EPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQ--VMRVRGEESEV 2789
L ++P+SL +SW P+ + ++Y+ P+ V R R +E
Sbjct: 1907 --------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1958
Query: 2790 TVGGLEPGRKYKMHLYGLHEGRRVGPV--------STVGVTEDEAETTQAV--------- 2832
T+ GLEPG +Y +++ L ++ P+ T VT +T +
Sbjct: 1959 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQ 2018
Query: 2833 -------------------PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFL 2873
PTT ++PR V ++SW + ++ +
Sbjct: 2019 PSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYII 2078
Query: 2874 VQYRNG-DGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2918
+ G D +P RVPG T++GL Y + + QR
Sbjct: 2079 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
Score = 277 bits (708), Expect = 2e-73
Identities = 328/1543 (21%), Positives = 584/1543 (37%), Gaps = 211/1543 (13%)
Query: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Y+ L YG E R +T + P T T P PL+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Query: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
Query: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Query: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
Query: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
Query: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
T+ +A T L + T ++ + W P Q + L
Sbjct: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
Query: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
Query: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
Query: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
Query: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
L P +Y +++Y + P+S + P PT+ L T
Sbjct: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA--VPPPTD----------------LRFT 1276
Query: 3174 GSSPDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKM 3230
PD++ ++W P +F V+Y + V + ++ V + L PG +Y +
Sbjct: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
Query: 3231 HLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSF 3290
+ ++E P+ T L +P ++ + +T++S + W + +
Sbjct: 1337 SVSSVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGY 1388
Query: 3291 LVQYRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAP 3348
+++ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV 1447
Query: 3349 DTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREV 3406
P +L V ATP S+ +SW P + + Y + G +Q V ++
Sbjct: 1448 SDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
Query: 3407 TVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLS 3466
T+ GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ +
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
Query: 3467 WTVAQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRL 3524
W + P + V ++ G + DQ +T+E L+P +Y
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV------------ 1609
Query: 3525 GPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSF 3584
VS E P + A + P+ L TD DS++++W QG +
Sbjct: 1610 --VSVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRY 1662
Query: 3585 VVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL 3642
V Y L DG++ + GL P + Y + LH+ PL +T +
Sbjct: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
Query: 3643 APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPL 3702
P + L T VT +SL W P + +R + P +
Sbjct: 1723 -----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTG 1763
Query: 3703 LQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQF 3762
+E+ + S V+ L T Y +++Y L+ + QG TL V PR +
Sbjct: 1764 PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARV 1822
Query: 3763 SEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVT 3822
++ ET+ ++W F+V A+G P + R+ + GL PG Y++
Sbjct: 1823 TDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
Query: 3823 VVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGA 3882
+ ++ S P+ +T D P+ LR L T ++ W+PP+ + Y ++ PG+
Sbjct: 1883 LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1942
Query: 3883 PPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 3922
PP + PG + + L T YT V L+ + P
Sbjct: 1943 PPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
Score = 254 bits (650), Expect = 1e-66
Identities = 370/1703 (21%), Positives = 624/1703 (36%), Gaps = 298/1703 (17%)
Query: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ--------- 817
+W P P + Y +++ P A +P ++Y +GL PG Y+
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 818 ----VTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
VT TS P + T P V +T ++ + W+ V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 868 DRFVVSYVSA--GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
F V Y + G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
G L +L T+ P P Q D+T + V W+
Sbjct: 796 DGEQSL-ILSTSQTTAPDAPPDPTVDQV------------------DDTS-IVVRWSRPQ 835
Query: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QESTPVV 893
Query: 1045 YQGIMDKDEEKPG--KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102
Q +E G +S P +L + T + + WT PE + + D
Sbjct: 894 IQ------QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVI 942
Query: 1103 PQVVPVEGPQRSAV-------ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPS 1155
P +P E QR + +T L PG Y F ++ + PL A Q
Sbjct: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTK 996
Query: 1156 PGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-DRDGRPQVVPVEGPERSFVV 1214
P NL + T ++ + WT P Q + + R G+P+ V + +
Sbjct: 997 LDAPT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
Query: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
+L P +Y +L I + T TT PP T VT
Sbjct: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTE 1100
Query: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR- 1333
++ ++WT A P F + + +QG V D + V GL P +Y + LR
Sbjct: 1101 TTIVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
Query: 1334 GRQRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSL 1388
G++R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1159 GQERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDIT 1204
Query: 1389 SLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1205 GYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQ 1507
P+S + A PP T+ L T++ P+++ ++W P +F+V+
Sbjct: 1256 SVPISDTIIPA-----VPPPTD---------LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Query: 1508 YKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565
Y + V + ++ V + NL P +Y +++ +++ PL
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR---------- 1351
Query: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPV 1623
K L+ G + +DIT +S + W P + +++ G+P+ V
Sbjct: 1352 ----GRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 1624 AADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVT 1683
+ +T+ +L P +Y + + +G+ SP+ + ++ PR +L V
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD------VPR--DLEVV 1457
Query: 1684 DPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFL 1740
TP SL +SW P + + + + G V V G + + T++ L G Y
Sbjct: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
Query: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800
+Y + G+ + + R+ +D KP ++QVT V NS+ + W
Sbjct: 1518 VYAVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSS 1566
Query: 1801 GQFDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISA 1858
+ V ++G P G E+++ GL P Y + +Y + P+
Sbjct: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
Query: 1859 VAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD- 1917
A+T P L + ++ ++W +G+ + + Y+
Sbjct: 1627 TAVT----------NIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
Query: 1918 RDGQLQMVRI-GGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976
DG ++ G+ + L GL Y V++ D P+
Sbjct: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI------------GT 1717
Query: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVP 2034
TA P P +L T TP SLS WT P Q + V+ + G K + +
Sbjct: 1718 QSTAIPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771
Query: 2035 GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAE 2094
V +SGL KY++++Y P V VT E +P P A
Sbjct: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP---------PRRAR 1821
Query: 2095 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGL 2153
VT ++ ++++SW F V +G+ + R + + T+ GL
Sbjct: 1822 --------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
Query: 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLS 2213
+PG YK++LY L++ R PV TA DAP + T +SL +S
Sbjct: 1874 QPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLATTPNSLLVS 1922
Query: 2214 WTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQR 2270
W P + ++++++ P+ V VP GV TI+GLEP +Y + + Q+
Sbjct: 1923 WQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
Query: 2271 VGPV--------SAVGLTAPGKD-----------------------EEMAPASTEPPTPE 2299
P+ +T PG D EE T PPT
Sbjct: 1982 SEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTA 2041
Query: 2300 PPI--KPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRV 2356
PI +PR V ++SW + ++ + + G D +P RVPG
Sbjct: 2042 TPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSA 2101
Query: 2357 TISGLEPDNKYKMNLYGFHGGQR 2379
T++GL Y + + QR
Sbjct: 2102 TLTGLTRGATYNIIVEALKDQQR 2124
Score = 224 bits (571), Expect = 1e-57
Identities = 304/1427 (21%), Positives = 520/1427 (36%), Gaps = 231/1427 (16%)
Query: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
Query: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
Query: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 919 PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978
A+ G+ T P T+ + ++
Sbjct: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
Query: 979 VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
+ WT P F+L +R +G A EV D +V PG Y ++ + G +
Sbjct: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
Query: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097
PI+ + + P G LTV+ S T P+ +
Sbjct: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
Query: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
+ G V Q S +L PG +Y +Y K P+ P
Sbjct: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
Query: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214
PP +L T+ PD++ ++W P F+V+Y V + + + + V+
Sbjct: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
Query: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
++L P +Y ++ + + PL T L+ P + + +T
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
Query: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332
+S + W + + +++ + G+P+ V N +T+ L P +Y +++ L
Sbjct: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
Query: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392
GR+ SP +G ++ S + +L V ++P SL + W
Sbjct: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
Query: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
P + + + Y + G + V G +S T+ GL+PG Y + +Y + G+
Sbjct: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510
P S+ ++ + E + ++ VTDV NS+ + W + V
Sbjct: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
Query: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568
K+ G + DQ E+T+ L+P +Y +++Y + + PL
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---------SQPLVQTAV 1629
Query: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQ 1627
T +P L TD+ DS+ ++W P+G+ + V Y DG ++ P A D
Sbjct: 1630 TNIDRPK------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP-APDG 1682
Query: 1628 REVT--IPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685
E T + L P +Y + + D P+ T A P +L T
Sbjct: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST---------AIPAPTDLKFTQV 1733
Query: 1686 TPDSLRLSWTVPEGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLLY 1742
TP SL WT P Q + V+ K+K GP + + + SV V+ L KY +Y
Sbjct: 1734 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
Query: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
L P A+ + PP+ +VT T+ ++ +SW
Sbjct: 1794 ALKDTLTSRP--------AQGVVTTLENVSPPR-----RARVTDATETTITISWRTKTET 1840
Query: 1803 FDSFVVQYKDRDGQ-PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861
F V +GQ P ++ +R ++ GL P YK+ LY L+ R P+ A
Sbjct: 1841 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
Query: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ 1921
TA + A TP ++L +SW + I+Y ++ G
Sbjct: 1901 TAIDAPSNLRFLATTP-----------------NSLLVSWQPPRARITGYIIKY-EKPGS 1942
Query: 1922 LQMVRIGGDR---NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEE------- 1971
+ R + T++GLE Y + + + + P+ TV +
Sbjct: 1943 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2002
Query: 1972 --------------EKPS----------------EPPTATP----EPPIKPRLGELTVTD 1997
++PS P TATP P P +G+ ++
Sbjct: 2003 YDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQ 2062
Query: 1998 ATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056
T +SW + ++ + + G D +P RVPG T++GL Y + +
Sbjct: 2063 TT-----ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 2117
Query: 2057 GFHGGQR---MGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE 2100
QR V VG + E PT+ S P +G+
Sbjct: 2118 ALKDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCFDPYTVSHYAVGD 2163
Score = 103 bits (257), Expect = 4e-21
Identities = 100/428 (23%), Positives = 166/428 (38%), Gaps = 60/428 (14%)
Query: 740 YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
YA GE P ++ G+ ++ +++ W G V Y + + +G
Sbjct: 1613 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1672
Query: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
F A +A + +GL PG EY V+V AL P T +T I P DL+
Sbjct: 1673 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
Query: 850 AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
VTPT+L W P ++ R V+ + + P++ +++ LM +Y V+
Sbjct: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
Query: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
V A + S PA G++ T + P R
Sbjct: 1792 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1821
Query: 968 VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027
V ET + + W + +T FQ+ G + + DVR + PGT Y+
Sbjct: 1822 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
Query: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
+ L+ + + S P++ D P L L T +SLL+ W P
Sbjct: 1881 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 1928
Query: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
++I+Y ++ G P +VVP P A IT L+PG +Y + ++ PL+
Sbjct: 1929 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1987
Query: 1145 EAKILPQS 1152
K + ++
Sbjct: 1988 RKKTVQKT 1995
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 308 bits (790), Expect = 6e-83
Identities = 371/1677 (22%), Positives = 642/1677 (38%), Gaps = 237/1677 (14%)
Query: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Y+ L YG E R +T + P T T P PL+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Query: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
Query: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Query: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
Query: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
Query: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
T+ +A T L + T ++ + W P Q + L
Sbjct: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
Query: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
Query: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
Query: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
Query: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
L P +Y +++Y + P+S + PE P L +L+
Sbjct: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTII------------------PEVPQLTDLSFV 1276
Query: 3174 GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGE---------ESEV---TVGG 3221
+ S+ L WT +S T+ G V GE +S V TV G
Sbjct: 1277 DITDSSIGLRWTP----LNSSTII-----GYRITVVAAGEGIPIFEDFVDSSVGYYTVTG 1327
Query: 3222 LEPGRKYKMHLYGLHEGQRVGPVSTVGITA-PLPTPLPVEPRLGELAVAAVTSDSVGLSW 3280
LEPG Y + + L G P + TA P PT +L + D++ ++W
Sbjct: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT---------DLRFTNIGPDTMRVTW 1378
Query: 3281 TVAQG-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRH 3337
+FLV+Y + + + +S AV ++ L P +Y + +
Sbjct: 1379 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1438
Query: 3338 GPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQ 3395
P+ +T D+ + +D T +S + W P + +++ + GR +
Sbjct: 1439 TPLRGRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1493
Query: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455
V ++ +T+ L P +Y + L+GR+ + +T ++P +L V
Sbjct: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEV 1547
Query: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKF 3513
T +SL +SW + + Y +T G + V + T T+ L+PG Y
Sbjct: 1548 VAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1607
Query: 3514 LLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLS 3573
+Y + G D+PA E + + VTD +S+ +
Sbjct: 1608 TVYAVTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1652
Query: 3574 WSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRL 3631
W + P + V NG P G DQ+++ I GL+P+ Y +Y +
Sbjct: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
Query: 3632 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 3691
PL T + RP+ L+ TDV S+++ WE+P G + + + P
Sbjct: 1713 QPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE 1761
Query: 3692 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 3751
E P P G +A L+ LR G+ Y++++ L ++ + GT T
Sbjct: 1762 DGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1813
Query: 3752 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKL 3810
P +P DL+F+++ TS W PP + ++V + P + + + + + +
Sbjct: 1814 P---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
Query: 3811 QGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQN 3868
GL+ +YEV+V +++ S P G +TT+ + P + R + TE + W+
Sbjct: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
Query: 3869 PVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITF 3927
+ + V V A G P+Q Y + L T+Y + L +SP I
Sbjct: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1990
Query: 3928 TTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQ 3985
+T ++AP +L TP + L++W P R GY++ + PG +E++ G+T
Sbjct: 1991 STAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 2050
Query: 3986 LLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 4042
+ GL P T Y + A+ P+ T + PF G + NG TS
Sbjct: 2051 ITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2106
Score = 306 bits (784), Expect = 3e-82
Identities = 422/1865 (22%), Positives = 694/1865 (37%), Gaps = 340/1865 (18%)
Query: 1993 LTVTDATPDSLSLSWTVPE-GQFDHFLVQYR--NGDGQPKAVRVPGHEEGVTISGLEPDH 2049
+T T + P+S + W P+ +++++R N G+ K +PGH TI GL+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2050 KYKMNLYGF--HGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSS 2107
Y+ L +G Q V+ T TP + P + +VT +
Sbjct: 676 VYEGQLISIQQYGHQE---VTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEIT 732
Query: 2108 PDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYG 2165
S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 733 ASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
Query: 2166 LHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHF- 2224
+ E G S + ++ + +PDAP TV + S+ + W+ P+ +
Sbjct: 793 ISED---GEQSLI-LSTSQTTAPDAP------PDPTVDQVDDTSIVVRWSRPQAPITGYR 842
Query: 2225 LVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGK 2284
+V + +G + +P + VT+S L+P +Y + +Y Q PV T
Sbjct: 843 IVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT--- 899
Query: 2285 DEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQP 2344
TP P +L + T +++ WT PE + V D P
Sbjct: 900 -----------GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIP 943
Query: 2345 KATRVPG-HEDRVTIS--------GLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEET 2395
+PG H R+ IS GL P Y ++ G+ P++A T + T
Sbjct: 944 --VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
Query: 2396 PSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY-KDRDGRPQV 2454
L + ++ + WT P+ + + + R G+P+
Sbjct: 1002 --------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
Query: 2455 VRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGT 2514
VG S+ + L+P +Y + L + +G + P +T T Q PG+
Sbjct: 1042 YNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ-----------PGS 1089
Query: 2515 EAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESK 2574
P P E+T T ++ ++WT P R F + + G V
Sbjct: 1090 SIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGS 1137
Query: 2575 VTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGEL 2634
+ V GL PG +Y + L +G+ E +A V T PP L
Sbjct: 1138 IVVSGLTPGVEYVYTIQVLRDGQ-----------ERDAPIVNKVVTPL-SPPTNLHL--- 1182
Query: 2635 TMTDATPDS--LSLSW---TVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEP 2688
+A PD+ L++SW T P+ NG G V + T L P
Sbjct: 1183 ---EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
Query: 2689 DHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSS 2748
+Y +++Y + PIS + PE P L +L+ +
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTII--------------------PEVPQLTDLSFVDIT 1279
Query: 2749 PDSLSLSWTIPQGHFDSFTVQYK-----DRDGRPQVMR-VRGEESEVTVGGLEPGRKYKM 2802
S+ L WT S + Y+ +G P V TV GLEPG Y +
Sbjct: 1280 DSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
Query: 2803 HLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSW 2862
+ L G + A TT T P P +L T+ PD++ ++W
Sbjct: 1337 SVITLING------------GESAPTTLTQQTAVPPPT------DLRFTNIGPDTMRVTW 1378
Query: 2863 MVPEG-QFDHFLVQYRNGDGQPKV--VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 2919
P +FLV+Y + V + + ++ V ++ L P +Y
Sbjct: 1379 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY------------- 1425
Query: 2920 GPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDS 2979
+SV V E TP T P + + + +S ++ W P+
Sbjct: 1426 -VVSVSSVYEQHESTPLRGRQKTGLDSPT------GIDFSDITANSFTVHWIAPRATITG 1478
Query: 2980 FTVQYKDR--DGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTA 3037
+ +++ GRP+ RV + +T+ L PG +Y + + L+ G+ P+ +G
Sbjct: 1479 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL-LIG--- 1533
Query: 3038 PKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY--RNG 3095
+ T VP +L V ATP SL +SW P ++ + Y G
Sbjct: 1534 ---QQSTVSDVPR------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGG 1578
Query: 3096 DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEP- 3154
+ + VPG + TISGL+P Y + +Y G ++P+ ++P
Sbjct: 1579 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG-------------RGDSPASSKPI 1625
Query: 3155 STEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQ-PQVVRVRG- 3212
S ++P ++ VT +S+S+ W + V ++G P + G
Sbjct: 1626 SINYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1683
Query: 3213 EESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVT 3272
+++E+T+ GL+P +Y + +Y + P+ +T R LA V
Sbjct: 1684 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN--------IDRPKGLAFTDVD 1735
Query: 3273 SDSVGLSWTVAQGPFDSFLVQYRDAQ-GQPQAVPV-SGDLRAVAVSGLDPARKYKFLLFG 3330
DS+ ++W QG + V Y + G + P G+ + GL P +Y +
Sbjct: 1736 VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1795
Query: 3331 LQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQY--K 3388
L + P+ TA P+P +L T TP S+ WT P + + V+ K
Sbjct: 1796 LHDDMESQPLIGTQSTA---IPAPT--DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1850
Query: 3389 DKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPP 3448
+K G ++ + +A + V V GL + KY +Y L P TT LE PP
Sbjct: 1851 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPP 1908
Query: 3449 HLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQ-PRAVPVAADQRTVTVEDLEP 3507
+T A ET ++ +SW F V +GQ P + D R+ T+ L+P
Sbjct: 1909 RRARVTDATET--TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1966
Query: 3508 GKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTP 3567
G YK LY L R PV TA + + LA TTP
Sbjct: 1967 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLA-------------------TTP 2007
Query: 3568 DSMRLSWSVAQGPFDSFVVQYEDTNGQPQALL--VDGDQSKILISGLEPSTPYRFLLYGL 3625
+S+ +SW + ++++YE P+ ++ ++ I+GLEP T Y + L
Sbjct: 2008 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 2067
Query: 3626 HEGKRLGPL------------------------SAEGTTGLAPA-GQ------------- 3647
++ PL GT+G P+ GQ
Sbjct: 2068 KNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTT 2127
Query: 3648 -----TSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHP--- 3699
T RPR +V S ++W AP F S + HP
Sbjct: 2128 PPTTATPIRHRPRPYPPNVGQEALSQTTISW-AP----------FQDTSEYIISCHPVGT 2176
Query: 3700 --RPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGP--HKA-DSIQGTARTLSPVL 3754
PL + VPGT SA L L G Y++ + L+ HK + + +++ L
Sbjct: 2177 DEEPL---QFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2233
Query: 3755 ESPRD 3759
P D
Sbjct: 2234 NQPTD 2238
Score = 304 bits (778), Expect = 1e-81
Identities = 359/1660 (21%), Positives = 629/1660 (37%), Gaps = 246/1660 (14%)
Query: 2309 LTVTDATPDSLSLSWTVPE-GQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDN 2365
+T T + P+S + W P+ +++++ KN G+ K +PGH + TI GL+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2366 KYKMNLYGF--HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGEL-TVTGS 2422
Y+ L +G Q V + T TP T ++ P PL+ +VT
Sbjct: 676 VYEGQLISIQQYGHQEV---TRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEI 731
Query: 2423 SPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
+ S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
Query: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
+ ED +++ + T AP P +P + ++ T S+ +
Sbjct: 792 QI-----------------SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-----SIVV 829
Query: 2541 SWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRL 2599
W+ PQ + + Y +G + + + VT+ L+PG +Y + +Y + E +
Sbjct: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
Query: 2600 GPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG-----Q 2654
PV Q T TP P +L + T +++ WT PE +
Sbjct: 890 TPV-----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYR 938
Query: 2655 FDHFLVQYRNGDGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGV 2713
D V GQ R+P ++GL P Y ++ G+ P++
Sbjct: 939 VDVIPVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
Query: 2714 TAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYK-D 2772
T + T L + ++ + WT P+ + +
Sbjct: 995 TKLDAPT--------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2773 RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAV 2832
R G+P+ V S+ + L+P +Y + L + +G + P +T GV T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKAT-GVF------TTLQ 1086
Query: 2833 PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHE 2892
P ++ P N T+ T ++ ++W P + F + R G V
Sbjct: 1087 PGSSIPPYN---------TEVTETTIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
Query: 2893 DGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEP 2951
+ +SGL P +Y + GQ R PI V PT EA P
Sbjct: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NP 1186
Query: 2952 LLGELTVT---GSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGL 3008
G LTV+ ++PD T T + G V ++S T L
Sbjct: 1187 DTGVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
Query: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068
PG +Y + +Y + KD+ E+ T+ PE P +L +L+ D
Sbjct: 1238 SPGLEYNVSVYTV-----------------KDDKESVPISDTIIPEVP---QLTDLSFVD 1277
Query: 3069 ATPDSLSLSWMVPEGQFDHFLVQYR-----NGDGQPKAVRVPGHEDGV-------TISGL 3116
T S+ L W ++ YR G+G +P ED V T++GL
Sbjct: 1278 ITDSSIGLRWTPLNSST---IIGYRITVVAAGEG------IPIFEDFVDSSVGYYTVTGL 1328
Query: 3117 EPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSS 3176
EP Y +++ G P + T P PT+ L T
Sbjct: 1329 EPGIDYDISVITLINGGESAPTTLTQQTA--VPPPTD----------------LRFTNIG 1370
Query: 3177 PDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLY 3233
PD++ ++W P +F V+Y + V + ++ V + L PG +Y + +
Sbjct: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1430
Query: 3234 GLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQ 3293
++E P+ T L +P ++ + +T++S + W + + ++
Sbjct: 1431 SVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGYRIR 1482
Query: 3294 YRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTK 3351
+ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1541
Query: 3352 PSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQ 3409
P +L V ATP S+ +SW P + + Y + G +Q V ++ T+
Sbjct: 1542 PR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
Query: 3410 GLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV 3469
GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ + W
Sbjct: 1598 GLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP 1655
Query: 3470 AQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPV 3527
+ P + V ++ G + DQ +T+E L+P +Y V
Sbjct: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV--------------V 1701
Query: 3528 SALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQ 3587
S E P + A + P+ L TD DS++++W QG + V
Sbjct: 1702 SVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
Query: 3588 YEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPA 3645
Y L DG++ + GL P + Y + LH+ PL +T +
Sbjct: 1757 YSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI--- 1813
Query: 3646 GQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQR 3705
P + L T VT +SL W P + +R + P + +
Sbjct: 1814 --------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTGPMK 1857
Query: 3706 ELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEI 3765
E+ + S V+ L T Y +++Y L+ + QG TL V PR + ++
Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDA 1916
Query: 3766 RETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVS 3825
ET+ ++W F+V A+G P + R+ + GL PG Y++ + +
Sbjct: 1917 TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1976
Query: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPL 3885
+ S P+ +T D P+ LR L T ++ W+PP+ + Y ++ PG+PP
Sbjct: 1977 LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
Query: 3886 QA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 3922
+ PG + + L T YT V L+ + P
Sbjct: 2037 EVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
Score = 299 bits (766), Expect = 3e-80
Identities = 396/1896 (20%), Positives = 691/1896 (36%), Gaps = 354/1896 (18%)
Query: 1683 TDPTPDSLRLSWTVPE-GQFDSFVVQFKDKDGP---QVVPVEGHERSVTVTPLDAGRKYR 1738
T P+S + W P+ ++++++ K+ + + GH S T+ L G Y
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
Query: 1739 FLLYGLLGKKRHGPLTADGTTEARS----AMDDTGTKRPPKPRLGEELQVTTVTQNSVGL 1794
L + D TT + S + TG P P + VT +T +S +
Sbjct: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
Query: 1795 SWTVPEGQFDSFVVQYK--DRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKR 1852
SW F V+Y+ + +PQ + + + V++P L P +Y + +Y +
Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-- 796
Query: 1853 VGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFE 1912
G S + T ++TTAP P P+P TV++ ++ + W + +
Sbjct: 797 -GEQSLILST-------SQTTAPDAP-PDP-----TVDQVDDTSIVVRWSRPQAPITGYR 842
Query: 1913 IQYTDR-DGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEE 1971
I Y+ +G + + N +TLS L+ +Y +T+Y + + PV ++ T
Sbjct: 843 IVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---- 898
Query: 1972 EKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV 2031
T TP P +L + T +++ WT PE + V D P V
Sbjct: 899 -------TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIP--V 944
Query: 2032 RVPG-HEEGVTIS--------GLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSP 2082
+PG H + + IS GL P Y ++ G+ P++ T + T
Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--- 1001
Query: 2083 TEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY-KDRDGRPQVVRV 2141
L + ++ + WT P+ + + + R G+P+ V
Sbjct: 1002 -----------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
Query: 2142 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMT 2201
G S+ + L+P +Y + L + +G + P A GV + P
Sbjct: 1045 GPSVSKYPLRNLQPASEYTVSLVAI-KGNQESP-KATGVFTTLQPGSSIPPYN------- 1095
Query: 2202 VRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 2261
++T ++ ++WT P + F + + G V + +SGL P +Y
Sbjct: 1096 -TEVTETTIVITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
Query: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTP-EPPIKPRLEELTVTDATPDS-- 2318
+ GQ E AP + TP PP LE A PD+
Sbjct: 1153 IQVLRDGQ----------------ERDAPIVNKVVTPLSPPTNLHLE------ANPDTGV 1190
Query: 2319 LSLSW---TVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
L++SW T P+ NG G V + T L P +Y +++Y
Sbjct: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
Query: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434
+ P+S + PE P L +L+ + S+ L WT
Sbjct: 1251 KDDKESVPISDTII--------------------PEVPQLTDLSFVDITDSSIGLRWTPL 1290
Query: 2435 QGRFDSFTVQYK-----DRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2488
S + Y+ +G P V TV GLEPG Y + + L G
Sbjct: 1291 N---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGES 1347
Query: 2489 GPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG- 2547
P + TA P PT +L T PD++ ++W P
Sbjct: 1348 APTTLTQQTA-------VPPPT----------------DLRFTNIGPDTMRVTWAPPPSI 1384
Query: 2548 RFDSFTVQYKDRDGRPQA--VRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAV 2605
+F V+Y + + ++ V + L PG +Y + + ++E P+
Sbjct: 1385 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444
Query: 2606 GVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--R 2663
T ++ T + +D T +S ++ W P + +++
Sbjct: 1445 QKTGLDSPT------------------GIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1486
Query: 2664 NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSP 2723
+ G+P+ RVP + +T++ L P +Y +++ +G EE+P
Sbjct: 1487 HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---------------REESPLL 1531
Query: 2724 TELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMR-- 2781
+ + P +L V ++P SL +SW P + + Y + G V
Sbjct: 1532 IGQQSTVSDVPR-----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
Query: 2782 VRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPN 2841
V G +S T+ GL+PG Y + +Y + GR P S+ ++ + T +P
Sbjct: 1587 VPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISIN-------YRTEIDKP-- 1636
Query: 2842 KPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKVVRVPGHEDGVTISG 2899
++ VTD +S+S+ W+ + V +NG G K + +TI G
Sbjct: 1637 ----SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1692
Query: 2900 LEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVT 2959
L+P +Y +++Y + P+ VT + + P+ L T
Sbjct: 1693 LQPTVEYVVSVYAQNPSGESQPLVQTAVT------------NIDRPK--------GLAFT 1732
Query: 2960 GSSPDSLSLSWTIPQGRFDSFTVQYKD-RDGRPQVVRV-RGEESEVTVGGLEPGCKYKMH 3017
DS+ ++W PQG+ + V Y DG ++ GEE + GL PG +Y +
Sbjct: 1733 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1792
Query: 3018 LYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLS 3077
+ LH+ P+ T A+P T +L T TP SLS
Sbjct: 1793 VVALHDDMESQPLIGTQST----------AIPAPT----------DLKFTQVTPTSLSAQ 1832
Query: 3078 WMVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 3135
W P Q + V+ + G K + + V +SGL KY++++Y
Sbjct: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
Query: 3136 GPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFT 3195
P + T E P VT ++ ++++SW F
Sbjct: 1893 RPAQGVVTTLENVSPPR----------------RARVTDATETTITISWRTKTETITGFQ 1936
Query: 3196 VQYKDRDGQPQVVR-VRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPV---STVGITA 3251
V +GQ + R ++ + T+ GL+PG YK++LY L++ R PV ++ I A
Sbjct: 1937 VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
Query: 3252 PLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAV---PVSG 3308
P L A T +S+ +SW + ++++Y P+ V P G
Sbjct: 1997 P-----------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
Query: 3309 DLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDS 3368
A ++GL+P +Y + L+N + K P +G TP
Sbjct: 2046 VTEA-TITGLEPGTEYTIYVIALKNNQ---------------KSEPLIGRKKTVQKTPFV 2089
Query: 3369 VGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRK 3428
+ G +Q+ + Q V Q +++ G +
Sbjct: 2090 THPGYDTGNG---------------IQLPGTSGQQPSVGQQ----------MIFEEHGFR 2124
Query: 3429 RLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYR-DTDGQ 3487
R P + + + PP++G +E S +SW Q + + + TD +
Sbjct: 2125 RTTPPTTATPIRHRPRPYPPNVG-----QEALSQTTISWAPFQDTSEYIISCHPVGTDEE 2179
Query: 3488 PRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKR 3523
P V + T+ L G Y ++ L +R
Sbjct: 2180 PLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2215
Score = 282 bits (722), Expect = 4e-75
Identities = 383/1698 (22%), Positives = 638/1698 (37%), Gaps = 292/1698 (17%)
Query: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEY---------- 816
+W P P + Y +++ P A +P ++Y +GL PG Y
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 817 ---QVTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
+VT TS P + T P V +T ++ + W+ V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 868 DRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
F V Y G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
G L +L T+ P P P + Q D+T + V W+
Sbjct: 796 DGEQSL-ILSTSQTTAPDAPPD------PTVDQ------------VDDTS-IVVRWSRPQ 835
Query: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE-NQESTPVV 893
Query: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104
Q ++ +S P +L + T + + WT PE + + D P
Sbjct: 894 IQ----QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPV 944
Query: 1105 VVPVEGPQR-------SAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
+P E QR A +T L PG Y F ++ + PL A Q
Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTKLD 998
Query: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY-RDRDGRPQVVPVEGPERSFVVSS 1216
P NL + T ++ + WT P Q + + R G+P+ V + + +
Sbjct: 999 APT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
Query: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
L P +Y +L I + T TT PP T VT +
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTETT 1102
Query: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR-GR 1335
+ ++WT A P F + + +QG V D + V GL P +Y + LR G+
Sbjct: 1103 IVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
Query: 1336 QRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSLSL 1390
+R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1161 ERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDITGY 1206
Query: 1391 FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1207 RIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYK- 1509
P+S T P P+L +L+ D+T +S+GL WT S I+ Y+
Sbjct: 1258 PIS--------------DTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRI 1300
Query: 1510 DKDGQPQVVPVAADQRE-----VTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLP 1564
+ +P+ D + TV LEP Y +++ L +G P ++ TA P
Sbjct: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP 1360
Query: 1565 PAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDGQPQV--V 1621
P +L T+I PD++ ++W P + +F+V+Y + V +
Sbjct: 1361 PT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1405
Query: 1622 PVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELW 1681
++ V + +L P +Y + + + +P+ KT G SP +
Sbjct: 1406 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG------ID 1456
Query: 1682 VTDPTPDSLRLSWTVPEGQFDSFVVQFKDK---DGPQVVPVEGHERSVTVTPLDAGRKYR 1738
+D T +S + W P + ++ + P+ V S+T+T L G +Y
Sbjct: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516
Query: 1739 FLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTV 1798
+ L G++ L +S + D PR +L+V T S+ +SW
Sbjct: 1517 VSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTSLLISWDA 1561
Query: 1799 PEGQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPI 1856
P + + Y + G Q V GS ++ GL P Y + +Y + G+ P
Sbjct: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPA 1620
Query: 1857 SAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT 1916
S+ I+ TE P+ ++ V + +++ + W+ + + + T
Sbjct: 1621 SSKPISI---NYRTEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
Query: 1917 DRD--GQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974
++ G + G D+ ++T+ GL+ Y+V++Y + P+ A+T + K
Sbjct: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
Query: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAVRV 2033
L TD DS+ ++W P+GQ + V Y + DG +
Sbjct: 1728 -----------------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
Query: 2034 P-GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEP 2092
P G E+ + GL P +Y +++ H P+ TA P+PT
Sbjct: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA----IPAPT--------- 1817
Query: 2093 AEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQVVRVGGEESEVTV 2150
+L T +P SLS WT P + + V+ K++ G + + + + S V V
Sbjct: 1818 -------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
Query: 2151 GGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSL 2210
GL KY++ +Y L + P V VT E SP + V D T ++
Sbjct: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSPPR--------RARVTDATETTI 1921
Query: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2269
++SW F V +GQ R + TI+GL+P YK+ LY +
Sbjct: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981
Query: 2270 RVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ 2329
R PV + AST P L TP+SL +SW P +
Sbjct: 1982 RSSPV-------------VIDASTAIDAP--------SNLRFLATTPNSLLVSWQPPRAR 2020
Query: 2330 FDHFLVQYKNGDGQPKATRVPGHEDRV---TISGLEPDNKYKMNLYGFHGGQRVGPVSAI 2386
++++Y+ G P VP V TI+GLEP +Y + + Q+ P+ I
Sbjct: 2021 ITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL--I 2077
Query: 2387 GVTAAEEETPSPTEPSME 2404
G ++TP T P +
Sbjct: 2078 GRKKTVQKTPFVTHPGYD 2095
Score = 281 bits (720), Expect = 7e-75
Identities = 372/1708 (21%), Positives = 649/1708 (37%), Gaps = 305/1708 (17%)
Query: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181
G +Y+ YG +G+ PL Q+ PS P + + T P+S + W
Sbjct: 582 GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
Query: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237
P+ +++++R ++ GR + + G S+ + L P Y L I ++YG
Sbjct: 633 PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
Query: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290
T T+ P PL+ +VT +T S +SW A
Sbjct: 690 QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
Query: 1291 FMVQYK--DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348
F V+Y+ + +PQ + + V +P L P RKY +N+Y + G +S++ T+
Sbjct: 750 FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
Query: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408
T AP++P +P + ++ T S+ + W+ PQ + + Y
Sbjct: 807 Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
Query: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467
+G + + + VT+ L+PG +Y + +Y + E Q PV Q+ET
Sbjct: 848 SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
Query: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524
S P +L +VT V + WT PE + ++ Q +P++ +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583
EVT L P Y ++ + G+ PL+ A + +K L +
Sbjct: 961 FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
Query: 1584 TVTDITPDSVGLSWTVPEGEFDSF-VVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642
TD T V + WT P + + + R GQP+ V + + +L+P+ +Y
Sbjct: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
Query: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701
L I+ G + SP + T + +S PP + T+ T ++ ++WT P F
Sbjct: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
Query: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTT- 1759
V + + P+ V S+ V+ L G +Y + + L G++R P+ T
Sbjct: 1116 KLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
Query: 1760 ----------------------EARSAMDDTG---TKRPPKPRLGEEL-QVTTVTQNSVG 1793
E + D TG T P + G L +V Q+S
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query: 1794 LSWTVPEGQFDSFVVQYK-DRDGQP---QVVPVEGSLREVSVPGLDPAH---RYKLLLYG 1846
P +++ V K D++ P ++P L ++S + + R+ L
Sbjct: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS 1293
Query: 1847 LHHGKRVGPISA---------------------------------VAITAGREETETETT 1873
G R+ ++A + + G E T T
Sbjct: 1294 TIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT 1353
Query: 1874 APTPPAPEPHLGELTVEEATSHTLHLSWMVTEG-EFDSFEIQYT--DRDGQLQMVRIGGD 1930
T P +L T+ ++W + +F ++Y+ + + + I
Sbjct: 1354 QQTAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPS 1410
Query: 1931 RNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRL 1990
N + L+ L Y+V++ + P+ ++ + PT
Sbjct: 1411 DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR------GRQKTGLDSPTG---------- 1454
Query: 1991 GELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPD 2048
+ +D T +S ++ W P + +++ + G+P+ RVP +T++ L P
Sbjct: 1455 --IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1512
Query: 2049 HKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSP 2108
+Y VS+V + EE P + + + +L V ++P
Sbjct: 1513 TEY--------------VVSIVALNGREE------SPLLIGQQSTVSDVPRDLEVVAATP 1552
Query: 2109 DSLSLSWTVPQGRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYGL 2166
SL +SW P + + Y + G Q V G +S T+ GL+PG Y + +Y +
Sbjct: 1553 TSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1612
Query: 2167 HEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLV 2226
GR P S+ ++ D P QM V D+ +S+S+ W + V
Sbjct: 1613 -TGRGDSPASSKPISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRV 1665
Query: 2227 QF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGK 2284
KNG G K + +TI GL+P +Y +++Y + P+ +T +
Sbjct: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1725
Query: 2285 DEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKN-GDGQ 2343
+ +A TD DS+ ++W P+GQ + V Y + DG
Sbjct: 1726 PKGLA---------------------FTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGI 1764
Query: 2344 PKATRVP-GHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPS 2402
+ P G ED + GL P ++Y +++ H P+ TA P+PT
Sbjct: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA----IPAPT--- 1817
Query: 2403 MEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQVVRVGGE 2460
+L T +P SLS WT P + + V+ K++ G + + + +
Sbjct: 1818 -------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864
Query: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
S V V GL KY++ +Y L + P GV E+V PP
Sbjct: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV--------------SPP 1908
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVR-VGGQESKVTVRG 2579
VT ++ ++++SW F V +G+ R + T+ G
Sbjct: 1909 R-----RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
Query: 2580 LEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDA 2639
L+PG YK++LY L++ R PV +A T P+ L
Sbjct: 1964 LQPGTDYKIYLYTLNDNARSSPVVI------DASTAIDAPS------------NLRFLAT 2005
Query: 2640 TPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMNL 2696
TP+SL +SW P + ++++Y P+ V VP GV TI+GLEP +Y + +
Sbjct: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYV 2064
Query: 2697 YGFHGGQRVGPISVIGVTAAEEETPSPT 2724
Q+ P+ IG ++TP T
Sbjct: 2065 IALKNNQKSEPL--IGRKKTVQKTPFVT 2090
Score = 278 bits (712), Expect = 6e-74
Identities = 379/1680 (22%), Positives = 631/1680 (37%), Gaps = 273/1680 (16%)
Query: 769 WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRAL-RGTS 827
W A V + +++ + EG P + +PS+A++ + L PG++Y V V +
Sbjct: 740 WVSASDTVSGFRVEYELSEEGDEPQYLD-LPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
Query: 828 WGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYV-SAGNQRVRLEV 886
L S + TT D P D V V T++ + W RPQA + + + Y S L +
Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
Query: 887 PPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPS 946
P A+ L+DL PGV+Y +T+ A S P ++ T +P + PS
Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP------RSDTVPS--- 909
Query: 947 TTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEE 1006
P++L + V T ++WT +++ + PG H +
Sbjct: 910 -------------PRDLQFVEVTDVKVT----IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
Query: 1007 VLPGDVRQ-ALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRL 1065
LP A V PG Y + V G + S P+ Q + K P L
Sbjct: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHG-RESKPLTAQ--------QTTKLDAPTNL 1003
Query: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK-DRDGQPQVVPVEGPQRSAVITSLDPGR 1124
+ TD T +L+RWT P + + + R GQP+ V + +L P
Sbjct: 1004 QFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
Query: 1125 KYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG 1184
+Y L G + + P PP+ T+ T ++ ++WT P
Sbjct: 1061 EYTVSLVAIKGNQESPKATG---VFTTLQPGSSIPPYN-----TEVTETTIVITWT-PAP 1111
Query: 1185 QFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN-KKRYGPLTADG 1243
+ F + R G V S VVS L P +Y +T+ + + ++R P+
Sbjct: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
Query: 1244 TTAPERKEEPPRPEFLE-QPLLGELTVT---GVTPD--SLRLSWTVAQGPFDSFMVQYKD 1297
T PP LE P G LTV+ TPD R++ T G
Sbjct: 1171 VTPLS----PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ---------- 1216
Query: 1298 AQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP 1357
QG V D++ T L P +Y +++Y ++ +D + P
Sbjct: 1217 -QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK-----------------DDKESVP 1258
Query: 1358 SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDR-----DGR 1412
+ PE P L +L+ + S+ L WT P S S + Y+ +G
Sbjct: 1259 ISDTI------IPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAGEGI 1309
Query: 1413 PRAVR-VGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATES 1471
P V TV GLEPG Y + + L G P T QQ PP T+
Sbjct: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTD- 1363
Query: 1472 PLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQYKDKDGQPQV--VPVAADQREVT 1528
L T++ P+++ ++W P +F+V+Y + V + ++ V
Sbjct: 1364 --------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1415
Query: 1529 VYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDI 1588
+ NL P +Y +++ +++ PL K L+ G + +DI
Sbjct: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLR--------------GRQKTGLDSPTG-IDFSDI 1460
Query: 1589 TPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAADQREVTIPDLEPSRKYKFLLF 1646
T +S + W P + +++ G+P+ V + +T+ +L P +Y +
Sbjct: 1461 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1520
Query: 1647 GIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706
+ +G+ SP+ + ++ PR +L V TP SL +SW P + +
Sbjct: 1521 AL-NGREESPLLIGQQSTVSD------VPR--DLEVVAATPTSLLISWDAPAVTVRYYRI 1571
Query: 1707 QFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARS 1763
+ + G V V G + + T++ L G Y +Y + G+ + + R+
Sbjct: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
Query: 1764 AMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQ-PQVVPV 1822
+D KP ++QVT V NS+ + W + V ++G P
Sbjct: 1632 EID--------KP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
Query: 1823 EG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPE 1881
G E+++ GL P Y + +Y + P+ A+T P
Sbjct: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT----------NIDRPKG-- 1728
Query: 1882 PHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD-RDGQLQMVRI-GGDRNDITLSGL 1939
L + ++ ++W +G+ + + Y+ DG ++ G+ + L GL
Sbjct: 1729 -----LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL 1783
Query: 1940 ESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDAT 1999
Y V++ D P+ TA P P +L T T
Sbjct: 1784 RPGSEYTVSVVALHDDMESQPLI------------GTQSTAIPAPT------DLKFTQVT 1825
Query: 2000 PDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYG 2057
P SLS WT P Q + V+ + G K + + V +SGL KY++++Y
Sbjct: 1826 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1885
Query: 2058 FHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTV 2117
P V VT E +P P A VT ++ ++++SW
Sbjct: 1886 LKDTLTSRPAQGV-VTTLENVSP---------PRRAR--------VTDATETTITISWRT 1927
Query: 2118 PQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2176
F V +G+ + R + + T+ GL+PG YK++LY L++ R PV
Sbjct: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
Query: 2177 AVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPK 2236
TA DAP + T +SL +SW P + ++++++ P+
Sbjct: 1988 IDASTA-----IDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
Query: 2237 AVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQRVGPV--------SAVGLTAPGKD 2285
V VP GV TI+GLEP +Y + + Q+ P+ +T PG D
Sbjct: 2037 EV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2095
Query: 2286 -----------------------EEMAPASTEPPTPEPPI--KPRLEELTVTDATPDSLS 2320
EE T PPT PI +PR V +
Sbjct: 2096 TGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTT 2155
Query: 2321 LSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
+SW + ++ + + G D +P RVPG T++GL Y + + QR
Sbjct: 2156 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2215
Score = 216 bits (551), Expect = 3e-55
Identities = 327/1500 (21%), Positives = 547/1500 (36%), Gaps = 286/1500 (19%)
Query: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
Query: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
Query: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 919 PAS---VRANTGSS--PLGLLGT------TDEPPPS-----GPSTTQGAQAPLLQQRPQE 962
A+ GSS P T T P P G +QG +AP ++ +
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAP--REVTSD 1134
Query: 963 LGELRVLG--------------RD----------------------------ETGRLRVV 980
G + V G RD +TG L V
Sbjct: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
Query: 981 W--TAQPDTFAYFQLRMRVPEGP------GAHEEVLPGDVRQALVPPPPPGTPYELSLHG 1032
W + PD Y R+ P + EEV+ D PG Y +S++
Sbjct: 1195 WERSTTPDITGY-----RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
Query: 1033 VPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSF 1092
V K S PI I + P+L +L+ D T S+ LRWT S
Sbjct: 1250 V-KDDKESVPISDTIIPE-----------VPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
Query: 1093 VIQYK-----DRDGQPQVVP-VEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGP--LVA 1144
+I Y+ +G P V+ +T L+PG Y + + P L
Sbjct: 1295 IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ 1354
Query: 1145 EAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV- 1202
+ + P +D L T+ PD++ ++W P F+V+Y V
Sbjct: 1355 QTAVPPPTD-----------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
Query: 1203 -VPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQ 1261
+ + + + V+++L P +Y ++ + + PL T L+
Sbjct: 1404 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDS 1451
Query: 1262 PLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGL 1319
P + + +T +S + W + + +++ + G+P+ V N +T+ L
Sbjct: 1452 PT--GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1509
Query: 1320 DPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELT 1379
P +Y +++ L GR+ SP +G ++ S + +L
Sbjct: 1510 TPGTEYVVSIVALNGREE--------------------SPLLIGQQSTVS---DVPRDLE 1546
Query: 1380 VTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYK 1437
V ++P SL + W P + + + Y + G + V G +S T+ GL+PG Y
Sbjct: 1547 VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1606
Query: 1438 MHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVP 1497
+ +Y + G+ P S+ ++ + E + ++ VTDV NS+ + W
Sbjct: 1607 ITVYAV-TGRGDSPASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPS 1656
Query: 1498 EGQFDSFIVQYKDKD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLS 1555
+ V K+ G + DQ E+T+ L+P +Y +++Y +
Sbjct: 1657 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE----- 1711
Query: 1556 VVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-R 1614
+ PL T +P L TD+ DS+ ++W P+G+ + V Y
Sbjct: 1712 ----SQPLVQTAVTNIDRPK------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE 1761
Query: 1615 DGQPQVVPVAADQREVT--IPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPG 1672
DG ++ P A D E T + L P +Y + + D P+ T
Sbjct: 1762 DGIHELFP-APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--------- 1811
Query: 1673 APPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVT 1729
A P +L T TP SL WT P Q + V+ K+K GP + + + SV V+
Sbjct: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS 1871
Query: 1730 PLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQ 1789
L KY +Y L P A+ + PP+ +VT T+
Sbjct: 1872 GLMVATKYEVSVYALKDTLTSRP--------AQGVVTTLENVSPPR-----RARVTDATE 1918
Query: 1790 NSVGLSWTVPEGQFDSFVVQYKDRDGQ-PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLH 1848
++ +SW F V +GQ P ++ +R ++ GL P YK+ LY L+
Sbjct: 1919 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
Query: 1849 HGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEF 1908
R P+ A TA + A TP ++L +SW
Sbjct: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTP-----------------NSLLVSWQPPRARI 2021
Query: 1909 DSFEIQYTDRDGQLQMVRIGGDR---NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEA 1965
+ I+Y ++ G + R + T++GLE Y + + + + P+
Sbjct: 2022 TGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
Query: 1966 LTVPEE---------------------EKPS----------------EPPTATP----EP 1984
TV + ++PS P TATP
Sbjct: 2081 KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2140
Query: 1985 PIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEEGVTIS 2043
P P +G+ ++ T +SW + ++ + + G D +P RVPG T++
Sbjct: 2141 PYPPNVGQEALSQTT-----ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2195
Query: 2044 GLEPDHKYKMNLYGFHGGQR---MGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE 2100
GL Y + + QR V VG + E PT+ S P +G+
Sbjct: 2196 GLTRGATYNIIVEALKDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCFDPYTVSHYAVGD 2254
Score = 103 bits (257), Expect = 4e-21
Identities = 100/428 (23%), Positives = 166/428 (38%), Gaps = 60/428 (14%)
Query: 740 YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
YA GE P ++ G+ ++ +++ W G V Y + + +G
Sbjct: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
Query: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
F A +A + +GL PG EY V+V AL P T +T I P DL+
Sbjct: 1764 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1822
Query: 850 AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
VTPT+L W P ++ R V+ + + P++ +++ LM +Y V+
Sbjct: 1823 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
Query: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
V A + S PA G++ T + P R
Sbjct: 1883 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1912
Query: 968 VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027
V ET + + W + +T FQ+ G + + DVR + PGT Y+
Sbjct: 1913 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
Query: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
+ L+ + + S P++ D P L L T +SLL+ W P
Sbjct: 1972 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 2019
Query: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
++I+Y ++ G P +VVP P A IT L+PG +Y + ++ PL+
Sbjct: 2020 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
Query: 1145 EAKILPQS 1152
K + ++
Sbjct: 2079 RKKTVQKT 2086
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 306 bits (784), Expect = 3e-82
Identities = 349/1581 (22%), Positives = 614/1581 (38%), Gaps = 266/1581 (16%)
Query: 1378 LTVTGSSPDSLSLFWTVPQGSFDS-FTVQYKDRD--GRPRAVRVGGKESEVTVGGLEPGH 1434
+T T S P+S + W PQ S S + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 1435 KYKMHL-----YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGEL-TVTDVTPN 1488
Y+ L YG E R + + P T +P P + +VT++T +
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
Query: 1489 SVGLSWTVPEGQFDSFIVQYK--DKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGL- 1545
S +SW F V+Y+ ++ +PQ + + + V + +L P RKY +N+Y +
Sbjct: 735 SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
Query: 1546 HDGQRMGPLSVVIVTAP-LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
DG++ LS TAP PP P TV + S+ + W+ P+
Sbjct: 795 EDGEQSLILSTSQTTAPDAPPDP----------------TVDQVDDTSIVVRWSRPQAPI 838
Query: 1605 DSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKT 1663
+ + Y +G + + VT+ DL+P +Y ++ +++ + +PV ++ +T
Sbjct: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
Query: 1664 VARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP----QVVPV 1719
+ PR +L + T + + WT PE + V + P Q +P+
Sbjct: 899 TGTPRSDTVPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 1720 EGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLG 1779
VT L G Y F ++ + + PLTA TT+ + +
Sbjct: 957 S-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN------------- 1002
Query: 1780 EELQVTTVTQNSVGLSWTVPEGQFDSFVVQYK-DRDGQPQVVPVEGSLREVSVPGLDPAH 1838
LQ T ++V + WT P Q + + R GQP+ V S+ + + L PA
Sbjct: 1003 --LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
Query: 1839 RYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLH 1898
Y +S VAI G +E+ T T P + E T T+
Sbjct: 1061 EYT--------------VSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIV 1104
Query: 1899 LSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV 1958
++W T F++ G + D I +SGL Y+ T+ DG+
Sbjct: 1105 ITW--TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 1959 GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT---DATPD--SLSLSWTVPEGQ 2013
+A V + P PPT P G LTV+ TPD ++ T GQ
Sbjct: 1163 -----DAPIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
Query: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073
+ L + + D + T L P +Y +++Y + P+S +
Sbjct: 1217 QGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP 1265
Query: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQG-RFDSFTVQYKDR 2132
A P PT+ L T PD++ ++W P +F V+Y
Sbjct: 1266 AV----PPPTD----------------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 2133 DGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDA 2190
V + ++ V + L PG +Y + + ++E P+ ++ D+
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG-----RQKTGLDS 1360
Query: 2191 PLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQF--KNGDGQPKAVRVPGHEDGVT 2248
P + DIT++S ++ W P + ++ ++ G+P+ RVP + +T
Sbjct: 1361 PTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
Query: 2249 ISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEE 2308
++ L P +Y +++ +G + +P + + S P +
Sbjct: 1415 LTNLTPGTEYVVSIVALNGREE----------SPLLIGQQSTVSDVP-----------RD 1453
Query: 2309 LTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNK 2366
L V ATP SL +SW P ++ + Y G+ + VPG + TISGL+P
Sbjct: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
Query: 2367 YKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP-SMEAPEPPEEPLLGELTVTGSSPD 2425
Y + +Y G ++P+ ++P S+ ++P ++ VT +
Sbjct: 1514 YTITVYAVTG---------------RGDSPASSKPISINYRTEIDKP--SQMQVTDVQDN 1556
Query: 2426 SLSLSWTVPQGRFDSF--TVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLH 2483
S+S+ W + T K+ G + G +++E+T+ GL+P +Y + +Y +
Sbjct: 1557 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1616
Query: 2484 EGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWT 2543
P+ VT P+PT+ L T +P SLS WT
Sbjct: 1617 PSGESQPLVQTAVTT-------IPAPTD----------------LKFTQVTPTSLSAQWT 1653
Query: 2544 VPQGRFDSFTVQY--KDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGP 2601
P + + V+ K++ G + + + S V V GL KY++ +Y L + P
Sbjct: 1654 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1713
Query: 2602 VSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQ 2661
V T + PP + R+ TDAT ++++SW F V
Sbjct: 1714 AQGVVTTLENVS-----------PPRRARV-----TDATETTITISWRTKTETITGFQVD 1757
Query: 2662 YRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEET 2720
+GQ R + TI+GL+P YK+ LY + R P+ + TA +
Sbjct: 1758 AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID--- 1814
Query: 2721 PSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQ-- 2778
AP L ++P+SL +SW P+ + ++Y+ P+
Sbjct: 1815 ---------APS--------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV 1857
Query: 2779 VMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPE 2838
V R R +E T+ GLEPG +Y +++ L ++
Sbjct: 1858 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK-------------------------- 1891
Query: 2839 PPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVPGHEDGVTI 2897
++P +G ++SW + ++ + + G D +P RVPG T+
Sbjct: 1892 --SEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATL 1949
Query: 2898 SGLEPDHKYKMNLYGFHGGQR 2918
+GL Y + + QR
Sbjct: 1950 TGLTRGATYNIIVEALKDQQR 1970
Score = 281 bits (718), Expect = 1e-74
Identities = 336/1516 (22%), Positives = 584/1516 (38%), Gaps = 201/1516 (13%)
Query: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584
+T T S P+S + W PQ + ++++ ++ GR + + G + T++GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641
Y+ L + + G + V+ T T T+T E P P + ++T+ T
Sbjct: 676 VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Query: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698
S +SW F V+Y GD +P+ + +P V I L P KY +N+Y
Sbjct: 734 SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
Query: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758
G S+I T+ T AP+ P +P + ++ T S+ + W+
Sbjct: 793 I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
Query: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
PQ + + Y +G + + + VT+ L+PG +Y + +Y + E + PV
Sbjct: 834 PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
Query: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872
Q T TP P +L + T +++ W PE + D
Sbjct: 893 ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
Query: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931
V GQ R+P ++GL P Y ++ G+ P++ T +
Sbjct: 943 PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
Query: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990
APT L + ++ + WT P+ + + + R G+
Sbjct: 999 ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050
P+ V S+ + L+P +Y VS V + ++ + T T
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
Query: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110
+ P I P E+T T ++ ++W P + F + R G V
Sbjct: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
Query: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167
+ +SGL P +Y + GQ R P+ V + TP PT EA P
Sbjct: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
Query: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224
G LTV+ ++PD T T + G V ++S T L P
Sbjct: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
Query: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
G +Y + +Y + + + P+S T +P P +L + D++ ++W
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
Query: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
+FLV+Y + + + +S AV ++ L P +Y + + P+
Sbjct: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
Query: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399
+T D+ + +D T +S + W P + +++ + GR + V
Sbjct: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459
++ +T+ L P +Y + L+GR+ + +T ++P +L V T
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
Query: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517
+SL +SW + + Y +T G + V + T T+ L+PG Y +Y
Sbjct: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
Query: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577
+ G D+PA E + + VTD +S+ + W +
Sbjct: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
Query: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635
P + V NG P G DQ+++ I GL+P+ Y +Y + PL
Sbjct: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
Query: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695
QT+ + P + L T VT +SL W P + +R +
Sbjct: 1626 -----------QTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------V 1666
Query: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755
P + +E+ + S V+ L T Y +++Y L+ + QG TL V
Sbjct: 1667 TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-S 1725
Query: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIP 3815
PR + ++ ET+ ++W F+V A+G P + R+ + GL P
Sbjct: 1726 PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
Query: 3816 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 3875
G Y++ + ++ S P+ +T D P+ LR L T ++ W+PP+ + Y +
Sbjct: 1786 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYII 1845
Query: 3876 QVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLE 3932
+ PG+PP + PG + + L T YT V L+ + P TG E
Sbjct: 1846 KYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE 1904
Query: 3933 APRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGITSHQLLGL 3989
A ++W P + Y++S H P G ++E L +PG TS L GL
Sbjct: 1905 ALSQ----------TTISWA-PFQDTSEYIISCH-PVGTDEEPLQFRVPGTSTSATLTGL 1952
Query: 3990 FPSTSYNARLQAMWGQ 4005
+YN ++A+ Q
Sbjct: 1953 TRGATYNIIVEALKDQ 1968
Score = 270 bits (690), Expect = 2e-71
Identities = 354/1627 (21%), Positives = 621/1627 (38%), Gaps = 283/1627 (17%)
Query: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181
G +Y+ YG +G+ PL Q+ PS P + + T P+S + W
Sbjct: 582 GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
Query: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237
P+ +++++R ++ GR + + G S+ + L P Y L I ++YG
Sbjct: 633 PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
Query: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290
T T+ P PL+ +VT +T S +SW A
Sbjct: 690 QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
Query: 1291 FMVQYKDAQ--GQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348
F V+Y+ ++ +PQ + + V +P L P RKY +N+Y + G +S++ T+
Sbjct: 750 FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
Query: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408
T AP++P +P + ++ T S+ + W+ PQ + + Y
Sbjct: 807 Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
Query: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467
+G + + + VT+ L+PG +Y + +Y + E Q PV Q+ET
Sbjct: 848 SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
Query: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524
S P +L +VT V + WT PE + ++ Q +P++ +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583
EVT L P Y ++ + G+ PL+ A + +K L +
Sbjct: 961 FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
Query: 1584 TVTDITPDSVGLSWTVPEGEFDSFVVQYK-DRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642
TD T V + WT P + + + R GQP+ V + + +L+P+ +Y
Sbjct: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
Query: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701
L I+ G + SP + T + +S PP + T+ T ++ ++WT P F
Sbjct: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
Query: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTTE 1760
V + + P+ V + S+ V+ L G +Y + + L G++R P+ T
Sbjct: 1116 KLGVRPSQGGEAPREVTSDSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT- 1172
Query: 1761 ARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW---TVPEGQFDSFVVQYKDRDGQP 1817
P P L+ T + +SW T P+ + + +GQ
Sbjct: 1173 ------------PLSPPTNLHLEANPDT-GVLTVSWERSTTPD--ITGYRITTTPTNGQQ 1217
Query: 1818 -----QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872
+VV + S + L P Y + +Y + K PIS +T
Sbjct: 1218 GNSLEEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPIS-------------DT 1262
Query: 1873 TAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEG-EFDSFEIQYTD--RDGQLQMVRIGG 1929
P P P +L T+ ++W + +F ++Y+ + + + I
Sbjct: 1263 IIPAVPPPT----DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
Query: 1930 DRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPR 1989
N + L+ L Y+V++ + P+ ++ + PT
Sbjct: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR------GRQKTGLDSPTG--------- 1363
Query: 1990 LGELTVTDATPDSLSLSWTVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEEGVTISGLEP 2047
+ +D T +S ++ W P + +++ + G+P+ RVP +T++ L P
Sbjct: 1364 ---IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
Query: 2048 DHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSS 2107
+Y VS+V + EE P + + + +L V ++
Sbjct: 1421 GTEYV--------------VSIVALNGREES------PLLIGQQSTVSDVPRDLEVVAAT 1460
Query: 2108 PDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYG 2165
P SL +SW P + + Y + G V V G +S T+ GL+PG Y + +Y
Sbjct: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
Query: 2166 LHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFL 2225
+ GR P S+ ++ D P QM V D+ +S+S+ W +
Sbjct: 1521 V-TGRGDSPASSKPISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
Query: 2226 VQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPG 2283
V KNG G K + +TI GL+P +Y +++Y + P+ +T
Sbjct: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT-- 1631
Query: 2284 KDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGD 2341
PA T+ L T TP SLS WT P Q + V+ K
Sbjct: 1632 -----IPAPTD--------------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
Query: 2342 GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP 2401
G K + V +SGL KY++++Y P + T
Sbjct: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT------------ 1720
Query: 2402 SMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2460
+E PP VT ++ ++++SW F V +G+ + R + +
Sbjct: 1721 -LENVSPPRRA-----RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
Query: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
T+ GL+PG YK++LY L++ R PV TA +AP
Sbjct: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---------------IDAP--- 1816
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV--RVGGQESKVTVR 2578
L ++P+SL +SW P+ R + ++Y+ P+ V R ++ T+
Sbjct: 1817 -----SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
Query: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
GLEPG +Y +++ L ++ P+ T EA L+ T
Sbjct: 1872 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA---------------------LSQT- 1909
Query: 2639 ATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
++SW + ++ + + G D +P RVPG T++GL Y + +
Sbjct: 1910 ------TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 1963
Query: 2698 GFHGGQR 2704
QR
Sbjct: 1964 ALKDQQR 1970
Score = 245 bits (625), Expect = 8e-64
Identities = 338/1558 (21%), Positives = 583/1558 (37%), Gaps = 271/1558 (17%)
Query: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ--------- 817
+W P P + Y +++ P A +P ++Y +GL PG Y+
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 818 ----VTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
VT TS P + T P V +T ++ + W+ V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 868 DRFVVSYVSA--GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
F V Y + G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
G L +L T+ P P Q D+T + V W+
Sbjct: 796 DGEQSL-ILSTSQTTAPDAPPDPTVDQV------------------DDTS-IVVRWSRPQ 835
Query: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QESTPVV 893
Query: 1045 YQGIMDKDEEKPG--KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102
Q +E G +S P +L + T + + WT PE + + D
Sbjct: 894 IQ------QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVI 942
Query: 1103 PQVVPVEGPQRSAV-------ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPS 1155
P +P E QR + +T L PG Y F ++ + PL A Q
Sbjct: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTK 996
Query: 1156 PGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-DRDGRPQVVPVEGPERSFVV 1214
P NL + T ++ + WT P Q + + R G+P+ V + +
Sbjct: 997 LDAPT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
Query: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
+L P +Y +L I + T TT PP T VT
Sbjct: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTE 1100
Query: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR- 1333
++ ++WT A P F + + +QG V D + V GL P +Y + LR
Sbjct: 1101 TTIVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
Query: 1334 GRQRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSL 1388
G++R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1159 GQERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDIT 1204
Query: 1389 SLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1205 GYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQ 1507
P+S + A PP T+ L T++ P+++ ++W P +F+V+
Sbjct: 1256 SVPISDTIIPA-----VPPPTD---------LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
Query: 1508 YKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565
Y + V + ++ V + NL P +Y +++ +++ PL
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR---------- 1351
Query: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPV 1623
K L+ G + +DIT +S + W P + +++ G+P+ V
Sbjct: 1352 ----GRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 1624 AADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVT 1683
+ +T+ +L P +Y + + +G+ SP+ + ++ PR +L V
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD------VPR--DLEVV 1457
Query: 1684 DPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFL 1740
TP SL +SW P + + + + G V V G + + T++ L G Y
Sbjct: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
Query: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800
+Y + G+ + + R+ +D KP ++QVT V NS+ + W
Sbjct: 1518 VYAVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSS 1566
Query: 1801 GQFDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISA 1858
+ V ++G P G E+++ GL P Y + +Y + P+
Sbjct: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
Query: 1859 VAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDR 1918
A+T T PAP +L + T +L W + + ++ T +
Sbjct: 1627 TAVT-------------TIPAPT----DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1669
Query: 1919 D--GQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976
+ G ++ + + D + + +SGL +Y V++Y D LT +P++
Sbjct: 1670 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----------TLT----SRPAQ 1715
Query: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-VPG 2035
T E PR VTDAT ++++SW F V +GQ R +
Sbjct: 1716 GVVTTLENVSPPRRAR--VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP 1773
Query: 2036 HEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEE 2095
TI+GL+P YK+ LY + R PV + TA ++AP
Sbjct: 1774 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAPS---- 1817
Query: 2096 PLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVV--RVGGEESEVTVGGL 2153
L ++P+SL +SW P+ R + ++Y+ P+ V R +E T+ GL
Sbjct: 1818 ----NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1873
Query: 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLS 2213
EPG +Y +++ L ++ P+ + + + GQ + T +S
Sbjct: 1874 EPGTEYTIYVIALKNNQKSEPL----------------IGRKKTGQEALSQTT-----IS 1912
Query: 2214 WTVPEGQFDHFLVQFKNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270
W + ++ + G D +P RVPG T++GL Y + + QR
Sbjct: 1913 WAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
Score = 243 bits (619), Expect = 4e-63
Identities = 319/1439 (22%), Positives = 555/1439 (38%), Gaps = 244/1439 (16%)
Query: 979 VVWTAQPDTFAYFQLRMRVPE-GPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGG 1037
V W + DT + F++ + E G LP +P PG Y ++++ + G
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
Query: 1038 KPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK 1097
+ S + +++ P + TV S+++RW+ P+ + I Y
Sbjct: 798 EQSLIL-----------STSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
Query: 1098 DR-DGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKIL--PQSDP 1154
+G + + S ++ L PG +Y +Y + P+V + + P+SD
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 1155 SPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFV- 1213
P +P L + VTD + + WT PE + V D P +P E +R +
Sbjct: 907 VP-SPRDLQFVEVTDV---KVTIMWTPPESAVTGYRV-----DVIPVNLPGEHGQRLPIS 957
Query: 1214 ------VSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267
V+ L P Y F +F +++ + PLTA TT + + P +F+ +
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT---KLDAPTNLQFVNE------ 1008
Query: 1268 TVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVPGLDPDRKYK 1326
T ++ + WT + + + +GQP+ V ++ + L P +Y
Sbjct: 1009 -----TDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
Query: 1327 MNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEA-PESPEEPLLGELTVTGSSP 1385
++L ++G Q E+P T + T P S P E+T T
Sbjct: 1064 VSLVAIKGNQ------------------ESPKATGVFTTLQPGSSIPPYNTEVTET---- 1101
Query: 1386 DSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHE 1445
++ + WT F + + G V + V GL PG +Y + L +
Sbjct: 1102 -TIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
Query: 1446 GQ-RVGPVSAVGVTAPQQEETPPATESPLE--PRLGELTVT---DVTPNSVG--LSWTVP 1497
GQ R P+ VT P T LE P G LTV+ TP+ G ++ T
Sbjct: 1159 GQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
Query: 1498 EGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVV 1557
GQ G V ADQ T NL P +Y +++Y + D + P+S
Sbjct: 1214 NGQ-----------QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
Query: 1558 IVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDG 1616
I+ A PP +L T+I PD++ ++W P + +F+V+Y
Sbjct: 1263 IIPAVPPPT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
Query: 1617 QPQV--VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAP 1674
+ V + ++ V + +L P +Y + + + +P+ KT G SP
Sbjct: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG- 1363
Query: 1675 PRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKD---GPQVVPVEGHERSVTVTPL 1731
+ +D T +S + W P + ++ + P+ V S+T+T L
Sbjct: 1364 -----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
Query: 1732 DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNS 1791
G +Y + L G++ L +S + D PR +L+V T S
Sbjct: 1419 TPGTEYVVSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTS 1463
Query: 1792 VGLSWTVPEGQFDSFVVQYKDRDGQPQV--VPVEGSLREVSVPGLDPAHRYKLLLYGLHH 1849
+ +SW P + + Y + G V V GS ++ GL P Y + +Y +
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT- 1522
Query: 1850 GKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD 1909
G+ P S+ I+ TE P+ ++ V + +++ + W+ +
Sbjct: 1523 GRGDSPASSKPISINYR---TEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVT 1570
Query: 1910 SFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALT 1967
+ + T ++G + G D+ ++T+ GL+ Y+V++Y + P+ A+T
Sbjct: 1571 GYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
Query: 1968 VPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGD 2025
P P +L T TP SLS WT P Q + V+ +
Sbjct: 1631 T------------IPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
Query: 2026 GQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEP 2085
G K + + V +SGL KY++++Y P V VT E +P
Sbjct: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP----- 1726
Query: 2086 SMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2144
P A VT ++ ++++SW F V +G+ + R + +
Sbjct: 1727 ----PRRAR--------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
Query: 2145 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRD 2204
T+ GL+PG YK++LY L++ R PV TA DAP +
Sbjct: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLA 1823
Query: 2205 ITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMN 2261
T +SL +SW P + ++++++ P+ V VP GV TI+GLEP +Y +
Sbjct: 1824 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIY 1882
Query: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSL 2321
+ Q+ P+ +G G+ E L+ T ++
Sbjct: 1883 VIALKNNQKSEPL--IGRKKTGQ----------------------EALSQT-------TI 1911
Query: 2322 SWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
SW + ++ + + G D +P RVPG T++GL Y + + QR
Sbjct: 1912 SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
Score = 224 bits (570), Expect = 2e-57
Identities = 271/1260 (21%), Positives = 479/1260 (38%), Gaps = 176/1260 (13%)
Query: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
Query: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
Query: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 919 PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978
A+ G+ T P T+ + ++
Sbjct: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
Query: 979 VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
+ WT P F+L +R +G A EV D +V PG Y ++ + G +
Sbjct: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
Query: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097
PI+ + + P G LTV+ S T P+ +
Sbjct: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
Query: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
+ G V Q S +L PG +Y +Y K P+ P
Sbjct: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
Query: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214
PP +L T+ PD++ ++W P F+V+Y V + + + + V+
Sbjct: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
Query: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
++L P +Y ++ + + PL T L+ P + + +T
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
Query: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332
+S + W + + +++ + G+P+ V N +T+ L P +Y +++ L
Sbjct: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
Query: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392
GR+ SP +G ++ S + +L V ++P SL + W
Sbjct: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
Query: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
P + + + Y + G + V G +S T+ GL+PG Y + +Y + G+
Sbjct: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510
P S+ ++ + E + ++ VTDV NS+ + W + V
Sbjct: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
Query: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568
K+ G + DQ E+T+ L+P +Y +++Y + PL VT PAP
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT--IPAPT 1636
Query: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVAAD 1626
+L T +TP S+ WT P + + V+ K++ G + + +A D
Sbjct: 1637 -------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
Query: 1627 QREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPT 1686
V + L + KY+ ++ ++D P T+ +PPR VTD T
Sbjct: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN-----VSPPRRAR--VTDAT 1736
Query: 1687 PDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744
++ +SW F V +G P ++ RS T+T L G Y+ LY L
Sbjct: 1737 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
Query: 1745 LGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFD 1804
R P+ D +T A+D L+ T NS+ +SW P +
Sbjct: 1797 NDNARSSPVVIDAST----AID-----------APSNLRFLATTPNSLLVSWQPPRARIT 1841
Query: 1805 SFVVQYKDRDGQP--QVVP-VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861
++++Y ++ G P +VVP + E ++ GL+P Y + + L + ++ P+
Sbjct: 1842 GYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL----- 1895
Query: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ 1921
GR++T E + T + P ++ + + + + T+ E F + T
Sbjct: 1896 -IGRKKTGQEALSQTTISWAP------FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSAT 1948
Query: 1922 LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTAT 1981
L + G N I + L+ R+ V + G V E L P ++ +P T +
Sbjct: 1949 LTGLTRGATYN-IIVEALKDQQRHKVREEVVTVGNSVN----EGLNQPTDDSCFDPYTVS 2003
Score = 205 bits (521), Expect = 9e-52
Identities = 310/1425 (21%), Positives = 518/1425 (36%), Gaps = 248/1425 (17%)
Query: 769 WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRAL-RGTS 827
W A V + +++ + EG P + +PS+A++ + L PG++Y V V +
Sbjct: 740 WVSASDTVSGFRVEYELSEEGDEPQYLD-LPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
Query: 828 WGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYV-SAGNQRVRLEV 886
L S + TT D P D V V T++ + W RPQA + + + Y S L +
Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
Query: 887 PPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPS 946
P A+ L+DL PGV+Y +T+ A S P ++ T +P + PS
Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP------RSDTVPS--- 909
Query: 947 TTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEE 1006
P++L + V T ++WT +++ + PG H +
Sbjct: 910 -------------PRDLQFVEVTDVKVT----IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
Query: 1007 VLPGDVRQ-ALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRL 1065
LP A V PG Y + V G + S P+ Q + K P L
Sbjct: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHG-RESKPLTAQ--------QTTKLDAPTNL 1003
Query: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK-DRDGQPQVVPVEGPQRSAVITSLDPGR 1124
+ TD T +L+RWT P + + + R GQP+ V + +L P
Sbjct: 1004 QFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
Query: 1125 KYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG 1184
+Y L G + + P PP+ T+ T ++ ++WT P
Sbjct: 1061 EYTVSLVAIKGNQESPKATG---VFTTLQPGSSIPPYN-----TEVTETTIVITWT-PAP 1111
Query: 1185 QFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN-KKRYGPLTADG 1243
+ F + R G V S VVS L P +Y +T+ + + ++R P+
Sbjct: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
Query: 1244 TTAPERKEEPPRPEFLE-QPLLGELTVT---GVTPD--SLRLSWTVAQGPFDSFMVQYKD 1297
T PP LE P G LTV+ TPD R++ T G
Sbjct: 1171 VTPLS----PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ---------- 1216
Query: 1298 AQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP 1357
QG V D++ T L P +Y +++Y ++ + P S + P
Sbjct: 1217 -QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-------IPAVP 1268
Query: 1358 SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQG-SFDSFTVQYKD--RDGRPR 1414
PT+L T PD++ + W P +F V+Y +
Sbjct: 1269 PPTDL----------------RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312
Query: 1415 AVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETP--PATESP 1472
+ + ++ V + L PG +Y + + ++E Q E TP ++
Sbjct: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYE---------------QHESTPLRGRQKTG 1357
Query: 1473 LEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDK--DGQPQVVPVAADQREVTVY 1530
L+ G + +D+T NS + W P + +++ + G+P+ V + +T+
Sbjct: 1358 LDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1531 NLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITP 1590
NL P +Y +++ L+ G+ PL + + S PR +L V TP
Sbjct: 1417 NLTPGTEYVVSIVALN-GREESPLLI------------GQQSTVSDVPR--DLEVVAATP 1461
Query: 1591 DSVGLSWTVPEGEFDSFVVQYKDRDGQPQV--VPVAADQREVTIPDLEPSRKYKFLLFGI 1648
S+ +SW P + + Y + G V V + TI L+P Y ++ +
Sbjct: 1462 TSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV 1521
Query: 1649 QDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQF 1708
G+ SP S +K ++ + P ++ VTD +S+ + W + V
Sbjct: 1522 T-GRGDSPAS--SKPISINYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1576
Query: 1709 KDKDGPQVVPVEG---HERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAM 1765
K+GP + + +T+ L +Y +Y PL T +
Sbjct: 1577 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPT 1636
Query: 1766 DDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQY--KDRDGQPQVVPVE 1823
D L+ T VT S+ WT P Q + V+ K++ G + + +
Sbjct: 1637 D---------------LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
Query: 1824 GSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPH 1883
V V GL A +Y++ +Y L P V T E +P A
Sbjct: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL-------ENVSPPRRA---- 1730
Query: 1884 LGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVR-IGGDRNDITLSGLESD 1942
V +AT T+ +SW F++ +GQ + R I D T++GL+
Sbjct: 1731 ----RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPG 1786
Query: 1943 HRYLVTLYGFSDGKHVGPVHVEALT--------------------------------VPE 1970
Y + LY +D PV ++A T + +
Sbjct: 1787 TDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIK 1846
Query: 1971 EEKPSEPPTATPEPPIKPRLGELTVTDATPDS---------------------------- 2002
EKP PP P +P + E T+T P +
Sbjct: 1847 YEKPGSPPREVVPRP-RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA 1905
Query: 2003 ---LSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGF 2058
++SW + ++ + + G D +P RVPG T++GL Y + +
Sbjct: 1906 LSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965
Query: 2059 HGGQR---MGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE 2100
QR V VG + E PT+ S P +G+
Sbjct: 1966 KDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCFDPYTVSHYAVGD 2009
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 291 bits (744), Expect = 1e-77
Identities = 240/823 (29%), Positives = 314/823 (38%), Gaps = 240/823 (29%)
Query: 125 CCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSAS 184
CCP ++G + T +HG +S TC CEPGWGGP CS D++ P S
Sbjct: 88 CCPGYYESGDFCIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGCDSD---HWGPHCS 143
Query: 185 GSCPDDCNDQGRC--VRGRCVCFPGYTGPSCGWPSCPGD----CQGRGRCVQGV------ 232
C C + C + G CVC G+ G C PG CQ +C G
Sbjct: 144 NRC--QCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA 201
Query: 233 --CVCRAGFSGPDCSQRSCPRG-----------CSQRGRCEG--GRCVCDPGYTGDDCGM 277
C+C G++G C + CP G C G C G C C PG+TG C
Sbjct: 202 GECLCAPGYTGVYCEEL-CPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCA- 259
Query: 278 RSCPRG-----------CSQRGRCEN--GRCVCNPGYTGEDCGVRSCPRG-----CSQRG 319
+ CP G C G+C++ G+C C GY G+ C CP G CSQ
Sbjct: 260 QPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQ-EECPFGSFGFQCSQHC 318
Query: 320 RCKDG--------RCVCDPGYTGEDCGTR-------------SCPWDCGEGGRC--VDGR 356
C +G C C+PGY G C R CP D C V G
Sbjct: 319 DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 378
Query: 357 CVCWPGYTGEDCSTRTCPRDCRGRG-----RCEDGE--------CICDTGYSGDDCGVRS 403
C C PG++G C+ +CP G G C++G C C G+ G+ C V
Sbjct: 379 CTCQPGWSGHHCN-ESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSC 437
Query: 404 CPG----------DCNQRGRCE--DGRCVCWPGYTGTDCGSRACPR-----DCRGRGRCE 446
G CN G C DG C C G+ G DC + CP +C C
Sbjct: 438 AAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLPCPSGTWGLNCNESCTCA 496
Query: 447 NGV--------CVCNAGYSGEDCGVRSCPG-----------DCRGRGRCE--SGRCMCWP 485
NG C C G+ G+ C + CP DC C+ +G C C
Sbjct: 497 NGAACSPIDGSCSCTPGWLGDTCEL-PCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLA 555
Query: 486 GYTGRDCGTRACPG----------DCRGRGRCV--DGRCVCNPGFTGEDCGSRRCPGDCR 533
G+TG C + PG C G C DG C C PGF G C R CP
Sbjct: 556 GWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC-QRICPPGFY 614
Query: 534 GHGLCE---------------DGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCED 578
GHG + G+C C G+SG C+ VC
Sbjct: 615 GHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQ------------------VCAG 656
Query: 579 GYSGEDCGVRQCPNDCSQHGVCQ--DGVCICWEGYVSEDCSIRTCPS-----------NC 625
GY G+DC + C C+ +G C DG C C+ G++ +DCS + CP +C
Sbjct: 657 GYFGQDCA-QLC--SCANNGTCSPIDGSCQCFPGWIGKDCS-QACPPGFWGPACFHACSC 712
Query: 626 HGRGRC--EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEP 683
H C E+G C C PG+TG C T+ CPA + G+DCG+
Sbjct: 713 HNGASCSAEDGACHCTPGWTGLFC-TQRCPA-----------------AFFGKDCGR--- 751
Query: 684 PASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPG----------DCRGRGECH--D 731
C G + +G+C C GF G C + PG +C C
Sbjct: 752 -VCQCQNGASCDHI--SGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVT 808
Query: 732 GSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPG 774
G+C C G+ G C + ++EE T+ +PA G
Sbjct: 809 GTCYCSPGFKGIRCDQAA--------LMMEELNPYTKISPALG 843
Score = 253 bits (647), Expect = 2e-66
Identities = 213/678 (31%), Positives = 261/678 (38%), Gaps = 188/678 (27%)
Query: 199 RGRCVCFPGY--TGPSCGWPSCPGDCQGRGRCVQ-GVCVCRAGFSGPDCSQRSCPRG--- 252
R R C PGY +G C P C +C GRCV C C G+ GPDCS C
Sbjct: 83 RRRSQCCPGYYESGDFC-IPLCTEECV-HGRCVSPDTCHCEPGWGGPDCSS-GCDSDHWG 139
Query: 253 --CSQRGRCEGGR--------CVCDPGYTGDDCGMRSCP----RGCSQRGRCENG----- 293
CS R +C+ G CVC G+ G C P +GC +C +G
Sbjct: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP 199
Query: 294 ---RCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGG 350
C+C PGYTG C++ +C PG G C R CP C GG
Sbjct: 200 RAGECLCAPGYTGV---------------YCEE---LCPPGSHGAHCELR-CP--CQNGG 238
Query: 351 RC--VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDC 408
C + G C C PG+TG C+ C G G +C + CP C
Sbjct: 239 TCHHITGECACPPGWTGAVCAQP------------------CPPGTFGQNCS-QDCP--C 277
Query: 409 NQRGRCED--GRCVCWPGYTGTDCGSRACPR-----------DCRGRGRCE--NGVCVCN 453
+ G+C+ G+C C GY G C CP DC G+C G C C
Sbjct: 278 HHGGQCDHVTGQCHCTAGYMGDRC-QEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECE 336
Query: 454 AGYSGEDCGVRSCPGDCRGRG-----RCES----------GRCMCWPGYTGRDCGTRACP 498
GY G C R CP G G C++ G C C PG++G C +CP
Sbjct: 337 PGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN-ESCP 395
Query: 499 ----GD-------CRGRGRC--VDGRCVCNPGFTGEDCGSRRCPG----------DCRGH 535
GD C+ C + G C C PGF GE C G C
Sbjct: 396 VGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG 455
Query: 536 GLCE--DGVCVCDAGYSGEDCSTRSCPGG-----------CRGRGQC--LDGRCVCEDGY 580
G C DG C C G+ G DC T CP G C C +DG C C G+
Sbjct: 456 GTCSPVDGSCTCKEGWQGLDC-TLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGW 514
Query: 581 SGEDCGVRQCPN-----DCSQHGVCQD--------GVCICWEGYVSEDCSIRTCPS---- 623
G+ C + CP+ +CS+H C G C C G+ C TCP
Sbjct: 515 LGDTCEL-PCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD-STCPPGRWG 572
Query: 624 -------NCHGRGRC--EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYG 674
+C G C E+G C C PG+ GP C R+CP G G C Q LC +
Sbjct: 573 PNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHG-CAQPCPLCV--HS 628
Query: 675 GEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECH--DG 732
C PG G LC VC G+ G DCA Q C C G C DG
Sbjct: 629 SRPCHHISGICECLPGFSGA--LCNQ---VCAGGYFGQDCA-QLC--SCANNGTCSPIDG 680
Query: 733 SCVCKDGYAGEDCGEEVP 750
SC C G+ G+DC + P
Sbjct: 681 SCQCFPGWIGKDCSQACP 698
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 289 bits (739), Expect = 5e-77
Identities = 247/835 (29%), Positives = 307/835 (36%), Gaps = 250/835 (29%)
Query: 125 CCPASAQAGTGQTDVRTLCSLHGVFDLSRC----TCSCEPGWGGPTCSDPTDAEIPPSSP 180
CCP ++G +HG RC TC CEPGWGG CS D +
Sbjct: 94 CCPGFYESGEMCVPHCADKCVHG-----RCIAPNTCQCEPGWGGTNCSSACDGD---HWG 145
Query: 181 PSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAG 238
P + C C + C + G C C G+ G C RC QG
Sbjct: 146 PHCTSRC--QCKNGALCNPITGACHCAAGFRGWRC-----------EDRCEQGT------ 186
Query: 239 FSGPDCSQRSCPRGCSQRGRCE--GGRCVCDPGYTGDDCGMRSCPRG-----CSQRGRCE 291
G DC QR C C+ G C C PGYTG C CP G C QR C+
Sbjct: 187 -YGNDCHQRC---QCQNGATCDHVTGECRCPPGYTGAFC-EDLCPPGKHGPQCEQRCPCQ 241
Query: 292 N--------GRCVCNPGYTGEDCGVRSCPRG-----CSQRGRCKDG--------RCVCDP 330
N G C C G+ G CG + CP G CSQ +C +G +C C P
Sbjct: 242 NGGVCHHVTGECSCPSGWMGTVCG-QPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
Query: 331 GYTGEDCGTRSCP-----------WDCGEGGRC--VDGRCVCWPGYTGEDCSTRTCPR-- 375
GYTGE C CP C GG+C V G C+C G+ GE C R CP
Sbjct: 301 GYTGERC-QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGL 359
Query: 376 ---DCRGRGRCE----------DGECICDTGYSGDDCGVRSCPG----DCNQRGRCED-- 416
C R C GEC C G+SG C PG C Q C++
Sbjct: 360 YGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGA 419
Query: 417 ------GRCVCWPGYTGTDCGSRACPR-----DCRGRGRCEN--------GVCVCNAGYS 457
G+C C PG+ G DC S CP +C R C+N G C C AG+
Sbjct: 420 DCDSVTGKCTCAPGFKGIDC-STPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWH 478
Query: 458 GEDCGVRSCPG-----------DCRGRGRCES--GRCMCWPGYTGRDCGTRACPG----- 499
G DC +R CP C G C + G C C PG+ G C G
Sbjct: 479 GVDCSIR-CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLN 537
Query: 500 -----DCRGRGRC--VDGRCVCNPGFTGEDCGS--------RRC--PGDCRGHGLC--ED 540
DC C G C C PG++G C S C P C+ C +D
Sbjct: 538 CAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDD 597
Query: 541 GVCVCDAGYSGEDCS------------TRSCPGGCRGRGQC--LDGRCVCEDGYSGEDCG 586
G+C C G+ G C +++CP G C + G C C G++G C
Sbjct: 598 GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCN 657
Query: 587 VRQCPN-----------DCSQHGVCQ--DGVCICWEGYVSEDCS------------IRTC 621
CP+ C+ +G C D C C+ G++ DCS I TC
Sbjct: 658 -EVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC 716
Query: 622 PSNCHGRGRCE--EGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCG 679
NCH C +G C C PG+TG C R C +G+ G+DC
Sbjct: 717 --NCHNGAFCSAYDGECKCTPGWTGLYCTQR------------------CPLGFYGKDCA 756
Query: 680 QEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPG-----------DCRGRGE 728
C G + +GQC C GF G C Q CP DC
Sbjct: 757 L----ICQCQNGADCDHI--SGQCTCRTGFMGRHCE-QKCPSGTYGYGCRQICDCLNNST 809
Query: 729 CH--DGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEI 781
C G+C C G+ G C + I G L +T P D+Y+I
Sbjct: 810 CDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTAL--------PADSYQI 856
Score = 97.8 bits (242), Expect = 2e-19
Identities = 91/291 (31%), Positives = 109/291 (37%), Gaps = 89/291 (30%)
Query: 480 RCMCWPGY--TGRDCGTRACPGDCRGRGRCV-DGRCVCNPGFTGEDCGSRRCPGD----- 531
+ C PG+ +G C C C GRC+ C C PG+ G +C S C GD
Sbjct: 91 KSQCCPGFYESGEMCVPH-CADKCV-HGRCIAPNTCQCEPGWGGTNCSSA-CDGDHWGPH 147
Query: 532 ------CRGHGLCED--GVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGE 583
C+ LC G C C AG+ G C R CE G G
Sbjct: 148 CTSRCQCKNGALCNPITGACHCAAGFRGWRCEDR------------------CEQGTYG- 188
Query: 584 DCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYT 643
NDC Q CQ+G +V+ +C CP G CE+ LC PG
Sbjct: 189 --------NDCHQRCQCQNGATC---DHVTGECR---CPPGYTG-AFCED---LCPPGKH 230
Query: 644 GPTCATRMCPADCRGRGRC--VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG 701
GP C R CP C+ G C V G C C G+ G CGQ
Sbjct: 231 GPQCEQR-CP--CQNGGVCHHVTGECSCPSGWMGTVCGQP-------------------- 267
Query: 702 QCVCVEGFRGPDCAIQTCPGDCRGRGECH--DGSCVCKDGYAGEDCGEEVP 750
C EG G +C+ Q C C G C G C C GY GE C +E P
Sbjct: 268 ---CPEGRFGKNCS-QEC--QCHNGGTCDAATGQCHCSPGYTGERCQDECP 312
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 285 bits (728), Expect = 9e-76
Identities = 246/791 (31%), Positives = 301/791 (38%), Gaps = 208/791 (26%)
Query: 119 EQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPS 178
E C C + G G ++ C D C C PG+ G C D A
Sbjct: 767 EDCEADC--PEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGW--- 821
Query: 179 SPPSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSCG-------W-PSCPGDCQ---GR 225
PS C C + G C G C C PG+TG SC W P C C G
Sbjct: 822 YGPSCQTRC--SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGH 879
Query: 226 GRC--VQGVCVCRAGFSGPDCSQRSCPRG-----CSQRGRCE--------GGRCVCDPGY 270
G C + G+C+C AG+ GP C Q+ CP+G C QR +C+ G C C G+
Sbjct: 880 GSCDAISGLCLCEAGYVGPRCEQQ-CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGW 938
Query: 271 TGDDCGMRSCPRG-----------CSQRGRCE--NGRCVCNPGYTGEDCGVRSCP----- 312
G C +CP G C+ C+ NG C+C G G C +CP
Sbjct: 939 RGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA-ETCPAHTYG 996
Query: 313 RGCSQRGRCKDG--------RCVCDPGYTGEDCGTRSCPWD-----------CGEGGRC- 352
CSQ C +G +C C PG+ G C ++CP C GG C
Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLCQNGGTCD 1055
Query: 353 -VDGRCVCWPGYTGEDCSTRTCPRD----CRGRGRC--------EDGECICDTGYSGDDC 399
V G C C G+ G C PRD CR G C G C+C G++GD C
Sbjct: 1056 PVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 1115
Query: 400 G---VRSCPGD-CNQRGRCEDGR--------CVCWPGYTGTDCGSRACP-----RDCRGR 442
+R G+ C QR C G C C PG+TG+ C +ACP DC
Sbjct: 1116 QSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC-EQACPPGSFGEDCAQM 1174
Query: 443 GRC--EN-------GVCVCNAGYSGEDCGVRSCPG----------DCRGRGRCES--GRC 481
+C EN G C C AGY G C R PG C G C++ G C
Sbjct: 1175 CQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGAC 1234
Query: 482 MCWPGYTGRDCGTRACPG----DCR-----GRGRCVD---GRCVCNPGFTGEDCGSRRCP 529
C G+ G DC G +C G+G D G C+C PG G C R CP
Sbjct: 1235 RCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC-ERGCP 1293
Query: 530 GD-----------CRGHGLCE--DGVCVCDAGYSGEDCSTRSCPG----------GCRGR 566
+ CR GLC +G C C G++G C PG C
Sbjct: 1294 QNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNN 1353
Query: 567 GQC--LDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRT-CPS 623
C G C C G+ G+ C CP HG G+C C G + S R CP+
Sbjct: 1354 STCEPATGTCRCGPGFYGQACE-HPCPPGF--HGAGCQGLCWCQHGAPCDPISGRCLCPA 1410
Query: 624 NCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGYGGEDCGQE 681
HG CE G C+PG G C R DC G C V G+CLC G G C +
Sbjct: 1411 GFHGHF-CERG---CEPGSFGEGCHQR---CDCDGGAPCDPVTGLCLCPPGRSGATCNLD 1463
Query: 682 EPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECH--DGSCVCKDG 739
CR GQ GP C + DC G +C G C C DG
Sbjct: 1464 ----------------CRRGQF-------GPSCTLHC---DCGGGADCDPVSGQCHCVDG 1497
Query: 740 YAGEDCGEEVP 750
Y G C E P
Sbjct: 1498 YMGPTCREGGP 1508
Score = 267 bits (683), Expect = 1e-70
Identities = 239/781 (30%), Positives = 295/781 (37%), Gaps = 231/781 (29%)
Query: 189 DDCNDQGRCVRGR--CVCFPGYTGPSCGWPSCPGD-----------CQGRGRC--VQGVC 233
DDC + G C+ G C C G+TG C +CP D CQ G C V G C
Sbjct: 525 DDCRNGGTCLLGLDGCDCPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
Query: 234 VCRAGFSGPDCSQRSCPRG-----------CSQRGRCEG--GRCVCDPGYTGDDCGMRSC 280
C G SG +C CP+G C+ RGRC G C+CDPG G C + +C
Sbjct: 584 RCPPGVSGTNCED-GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL-TC 641
Query: 281 PR-----GCSQRGRC----------ENGRCVCNPGYTGE----DCGVRSCPRGCSQRGRC 321
P GCS+ +C +G C C G+ GE +C + GC Q C
Sbjct: 642 PPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTC 701
Query: 322 K--------DGRCV--CDPGYTGEDCGTR--------SCPWDCGEGGR-C--VDGRCVCW 360
G C C G+ GEDCG +C C GG C V G+C C
Sbjct: 702 PVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCP 761
Query: 361 PGYTGEDCSTRTCPRD------------CRGRGRC--EDGECICDTGYSGDDCGVRSCPG 406
PG TGEDC CP C+ RC E G C+C G+ G C CP
Sbjct: 762 PGRTGEDCEA-DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQ-DVCPA 819
Query: 407 -----------DCNQRGRCED--GRCVCWPGYTGTDCGSRAC-----------PRDCR-G 441
C G C G C C PG+TG C RAC P +C G
Sbjct: 820 GWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC-QRACDTGHWGPDCSHPCNCSAG 878
Query: 442 RGRCE--NGVCVCNAGYSGEDCGVRSCPGD-----CRGRGRCE--------SGRCMCWPG 486
G C+ +G+C+C AGY G C + CP C R +C+ SG C C G
Sbjct: 879 HGSCDAISGLCLCEAGYVGPRCE-QQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG 937
Query: 487 YTGRDCGTRACPG-----DCRGRGRC--------VDGRCVCNPGFTGEDCGSRRCPGDCR 533
+ G C ACP DCR C V+G C+C G G C + CP
Sbjct: 938 WRGTFC-EHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC-AETCPAHTY 995
Query: 534 GHGLCE-------------DGVCVCDAGYSGEDCSTRSCPGG-----------CRGRGQC 569
GH + G C C G+ G C ++CP G C+ G C
Sbjct: 996 GHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLCQNGGTC 1054
Query: 570 --LDGRCVCEDGYSGEDCGVRQCPND----------CSQHGVCQD--GVCICWEGYVSED 615
+ G C C +G++G C P D C G+C G C+C G+ +
Sbjct: 1055 DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDK 1114
Query: 616 CSI--------RTCPSNCH--GRGRCEE--GRCLCDPGYTGPTCATRMCPA-----DCRG 658
C C C C G C C PG+TG C + CP DC
Sbjct: 1115 CQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE-QACPPGSFGEDCAQ 1173
Query: 659 RGRC---------VQGVCLCHVGYGGEDCGQEEPPASACPG-----GCGPRELCRA--GQ 702
+C G C C GY G C Q PP PG GC C A G
Sbjct: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
Query: 703 CVCVEGFRGPDCAIQTCP-----GDCR-----GRGECHD---GSCVCKDGYAGEDCGEEV 749
C C GF G DC + TCP +C G+G D G+C+C G AG C
Sbjct: 1234 CRCPTGFLGTDCNL-TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGC 1292
Query: 750 P 750
P
Sbjct: 1293 P 1293
Score = 206 bits (525), Expect = 3e-52
Identities = 254/907 (28%), Positives = 313/907 (34%), Gaps = 303/907 (33%)
Query: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQC--TGGCCPASAQAGTG-QTDVRT 141
C CPPG + P +V R G + +C T G + G TD RT
Sbjct: 147 CHCPPGFQGPRCQYDVDECRTHNG-------GCQHRCVNTPGSYLCECKPGFRLHTDSRT 199
Query: 142 L------------CSLHGV-FDLSRCTCSCEPGW----GGPTCSDPTDAEIPPSSPPSAS 184
C H V ++R C C PG+ G C + S + +
Sbjct: 200 CLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC-------VRRSPCANRN 252
Query: 185 GSCPDDCNDQGRCVRG--RCVCFPGYTGPSCGWPSCPG--DCQ-GRGRCVQGV------- 232
GSC C + VRG RC C GY + G +C +C G +C G
Sbjct: 253 GSCMHRC----QVVRGLARCECHVGYQLAADG-KACEDVDECAAGLAQCAHGCLNTQGSF 307
Query: 233 -CVCRAGFS----GPDC-------------SQRSCPRGCSQRGRCEGGRCVCDPGYT--- 271
CVC AG+ G C + C GCS G C C GY
Sbjct: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA--GPLCTCPRGYELDT 365
Query: 272 -------GDDCGMRSCPRGCSQRGRCENG----RCVCNPGY--TGEDCGVRSCPRGCSQR 318
DDC C C Q C N C C GY + + CG S R
Sbjct: 366 DQRTCIDVDDCADSPC---CQQV--CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSR 420
Query: 319 GRCKDG--------RCVCDPGYT-------------------GEDCGTRSCPW------- 344
G C+ +C C+ GY GE R P
Sbjct: 421 GGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDE 480
Query: 345 --------DCG--------EGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG-- 386
D G G + + VC G DCS TC DCR G C G
Sbjct: 481 LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSL-TCD-DCRNGGTCLLGLD 538
Query: 387 ECICDTGYSGDDCGVRSCPGD-----------CNQRGRCED--GRCVCWPGYTGTDCGSR 433
C C G++G C +CP D C G C+ G C C PG +GT+C
Sbjct: 539 GCDCPEGWTGLICN-ETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNC--- 594
Query: 434 ACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCES--GRCMCWPGYTGRD 491
E+G C GY G+ C + C +C RGRC G C+C PG GR
Sbjct: 595 ------------EDG---CPKGYYGKHCR-KKC--NCANRGRCHRLYGACLCDPGLYGRF 636
Query: 492 CGTRACPGDCRGRG-----RCV----------DGRCVCNPGFTGEDCGSRRCPGDCR--- 533
C CP G G +CV DG C C GF GE RC +C
Sbjct: 637 CHL-TCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE-----RCQAECELGY 690
Query: 534 -GHGL-----CEDGVCV----------CDAGYSGEDCSTRSCPGG-----CRGRGQC--- 569
G G C GV C AG+ GEDC + CP G C C
Sbjct: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG-QECPVGTFGVNCSSSCSCGGA 749
Query: 570 ----LDGRCVCEDGYSGEDCGVRQCPND------------CSQHGVC--QDGVCICWEGY 611
+ G+C C G +GEDC CP C C + G C+C G+
Sbjct: 750 PCHGVTGQCRCPPGRTGEDCEA-DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGF 808
Query: 612 VSEDCSIRTCPS-----------NCHGRGRCEE--GRCLCDPGYTGPTCATRMC------ 652
V C CP+ +C G C G C C PG+TG +C R C
Sbjct: 809 VGSRCQ-DVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQ-RACDTGHWG 866
Query: 653 -----PADCR-GRGRC--VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR----- 699
P +C G G C + G+CLC GY G C Q+ P P GC R C+
Sbjct: 867 PDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGP-GCEQRCQCQHGAAC 925
Query: 700 ---AGQCVCVEGFRGPDCAIQTCPG-----DCRGRGECH--------DGSCVCKDGYAGE 743
+G C C G+RG C CP DCR C +GSC+C G G
Sbjct: 926 DHVSGACTCPAGWRGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGP 984
Query: 744 DCGEEVP 750
C E P
Sbjct: 985 RCAETCP 991
Score = 53.5 bits (127), Expect = 4e-06
Identities = 78/299 (26%), Positives = 102/299 (34%), Gaps = 88/299 (29%)
Query: 501 CRGRGRCVDGR---CVCNPGFTGEDCGSRRCPGDCRGH-GLCE--------DGVCVCDAG 548
C GRCV G C C PGF G C + +CR H G C+ +C C G
Sbjct: 133 CFHGGRCVPGSAQPCHCPPGFQGPRC--QYDVDECRTHNGGCQHRCVNTPGSYLCECKPG 190
Query: 549 Y-----SGEDCSTRSCP---GGCRGRGQCLD-----GRCVCEDGYSGEDCGVRQCPNDCS 595
+ S + SC GGC + C+ RC C G+ ++ G C
Sbjct: 191 FRLHTDSRTCLAINSCALGNGGC--QHHCVQLTITRHRCQCRPGFQLQEDG-----RHCV 243
Query: 596 QHGVC--QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGY----TGPTCA- 648
+ C ++G C+ C + G RCE C GY G C
Sbjct: 244 RRSPCANRNGSCM-------HRCQV------VRGLARCE-----CHVGYQLAADGKACED 285
Query: 649 TRMCPADCRGRGRCVQGV--------CLCHVGY----GGEDCGQEE----PPASACPGGC 692
C A G +C G C+CH GY G C + E A GGC
Sbjct: 286 VDECAA---GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
Query: 693 --GPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSC---VCKDGYAGEDCG 746
G C C G+ + T C +C D C VC + G +CG
Sbjct: 343 SHGCSHTSAGPLCTCPRGYE-----LDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECG 396
Score = 43.1 bits (100), Expect = 0.006
Identities = 51/174 (29%), Positives = 67/174 (38%), Gaps = 41/174 (23%)
Query: 609 EGYVSEDCSIRTCPSNCHGRGRCEEGR---CLCDPGYTGPTCATRMCPADCRGRG----- 660
EG +S +CS C HG GRC G C C PG+ GP C + +CR
Sbjct: 121 EGCLSAECSASLC---FHG-GRCVPGSAQPCHCPPGFQGPRCQYDV--DECRTHNGGCQH 174
Query: 661 RCVQG----VCLCHVGYGGEDCGQEEPPASACP---GGCG---PRELCRAGQCVCVEGF- 709
RCV +C C G+ + ++C GGC + +C C GF
Sbjct: 175 RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQ 234
Query: 710 ---------RGPDCAIQ--TCPGDCR-----GRGECHDGSCVCKDGYAGEDCGE 747
R CA + +C C+ R ECH G + DG A ED E
Sbjct: 235 LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDE 288
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 283 bits (723), Expect = 3e-75
Identities = 339/1511 (22%), Positives = 570/1511 (37%), Gaps = 237/1511 (15%)
Query: 2208 DSLSLSWTVPE-GQFDHFLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2264
+S + W P+ +++++ KN G+ K +PGH + TI GL+P Y+ L
Sbjct: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
Query: 2265 F--HGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLS 2322
+G Q V T + T TP P+ E +VT+ T S +S
Sbjct: 684 IQQYGHQEVTRFDFT--TTSTSTPVTSNTVTGETTPFSPLVATSE--SVTEITASSFVVS 739
Query: 2323 WTVPEGQFDHFLVQYK---NGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
W F V+Y+ GD +P+ +P V I L P KY +N+Y
Sbjct: 740 WVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVY------- 791
Query: 2380 VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD 2439
+S G + T T AP+ P +P + ++ T S+ + W+ PQ
Sbjct: 792 --QISEDGEQSLILSTSQTT-----APDAPPDPTVDQVDDT-----SIVVRWSRPQAPIT 839
Query: 2440 SFTVQYKDR-DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTA 2498
+ + Y +G + + + VT+ L+PG +Y + +Y + E + PV T
Sbjct: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Query: 2499 PQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG-----RFDSFT 2553
D PSP + L + +++ WT P+ R D
Sbjct: 900 GTPRSDTVPSPRD----------------LQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
Query: 2554 VQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAE 2613
V G+ + + + V GL PG Y ++ + GR P++A T+ +A
Sbjct: 944 VNLPGEHGQRLPI---SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
Query: 2614 TTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAV 2672
T L + T ++ + WT P Q + L GQP+
Sbjct: 1001 TN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 2673 RVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTEL-STEAP 2731
V + L+P +Y ++L G Q E+P T + +T P
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQ---------------ESPKATGVFTTLQP 1087
Query: 2732 EPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTV 2791
P E+T T ++ ++WT P F + + G V + + V
Sbjct: 1088 GSSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 2792 GGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPN-----KPRLG 2846
GL PG +Y + L +G+ E +A V T P N P G
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQ-----------ERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
Query: 2847 ELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLE 2901
LTV+ TPD ++ GQ + L + + D + T L
Sbjct: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLS 1238
Query: 2902 PDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGS 2961
P +Y +++Y + PIS +T P P PP + L T
Sbjct: 1239 PGLEYNVSVYTVKDDKESVPIS---------DTIIPAVP------PPTD-----LRFTNI 1278
Query: 2962 SPDSLSLSWTIPQG-RFDSFTVQYKDRDGRPQVVR--VRGEESEVTVGGLEPGCKYKMHL 3018
PD++ ++W P +F V+Y V + ++ V + L PG +Y + +
Sbjct: 1279 GPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1338
Query: 3019 YGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSW 3078
++E P+ + +T PT + +D T +S ++ W
Sbjct: 1339 SSVYEQHESTPL--------RGRQKTGLDSPT------------GIDFSDITANSFTVHW 1378
Query: 3079 MVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVG 3136
+ P + +++ + G+P+ RVP + +T++ L P +Y +++ +G
Sbjct: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1433
Query: 3137 PVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 3196
EE+P + + P + L V ++P SL +SW P + +
Sbjct: 1434 --------REESPLLIGQQSTVSDVPRD-----LEVVAATPTSLLISWDAPAVTVRYYRI 1480
Query: 3197 QYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Y + G V V G +S T+ GL+PG Y + +Y + G+ P S+ I+
Sbjct: 1481 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYR 1539
Query: 3255 TPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQ-PQAVPVSG-DLRA 3312
T + + ++ V V +S+ + W + P + V G P +G D
Sbjct: 1540 TEID---KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
Query: 3313 VAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLS 3372
+ + GL P +Y ++ P+ +TA T P+P +L T TP S+
Sbjct: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPL---VQTAVTTIPAPT--DLKFTQVTPTSLSAQ 1651
Query: 3373 WTVPEGEFDSFVVQY--KDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRL 3430
WT P + + V+ K+K G ++ + +A + V V GL + KY +Y L
Sbjct: 1652 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711
Query: 3431 GPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQ-PR 3489
P TT LE PP +T A ET+ + +SW F V +GQ P
Sbjct: 1712 RPAQGVVTT--LENVSPPRRARVTDATETT--ITISWRTKTETITGFQVDAVPANGQTPI 1767
Query: 3490 AVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAP 3549
+ D R+ T+ L+PG YK LY L R PV TA + + LA
Sbjct: 1768 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLA---- 1823
Query: 3550 EPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQ--SKI 3607
TTP+S+ +SW + ++++YE P+ ++ ++
Sbjct: 1824 ---------------TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868
Query: 3608 LISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTS 3667
I+GLEP T Y + L ++ PL T P Q P L + DV ++
Sbjct: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP--QLVTLPHPNLHGPEILDVPST 1926
Query: 3668 SLRLNWEAPPG 3678
+ + PG
Sbjct: 1927 VQKTPFVTHPG 1937
Score = 278 bits (712), Expect = 6e-74
Identities = 315/1407 (22%), Positives = 546/1407 (38%), Gaps = 174/1407 (12%)
Query: 2634 LTMTDATPDSLSLSWTVPE-GQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDH 2690
+T T + P+S + W P+ +++++R N G+ K +PGH + TI GL+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2691 KYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEP-PEEPLLGEL-TVTGSS 2748
Y+ L Q+ G V T +P +T E P PL+ +VT +
Sbjct: 676 VYEGQLISI---QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEIT 732
Query: 2749 PDSLSLSWTIPQGHFDSFTVQYK--DRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYG 2806
S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 733 ASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
Query: 2807 LHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPE 2866
+ E G S + T TT P+ P P TV S+ + W P+
Sbjct: 793 ISED---GEQSLILSTSQ---------TTAPDAPPDP-----TVDQVDDTSIVVRWSRPQ 835
Query: 2867 GQFDHFLVQYRNG-DGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVI 2925
+ + Y +G + +P + VT+S L+P +Y + +Y Q P+ +
Sbjct: 836 APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI- 894
Query: 2926 GVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG-----RFDSF 2980
+E T P + +P + + ++ VT + WT P+ R D
Sbjct: 895 ----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVTGYRVDVI 942
Query: 2981 TVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKD 3040
V G+ + R +EVT GL PG Y ++ + G+ P++A T K
Sbjct: 943 PVNLPGEHGQRLPIS-RNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KL 997
Query: 3041 EAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRNGDGQP 3099
+A T L + T ++ + W P Q + L GQP
Sbjct: 998 DAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP 1039
Query: 3100 KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAP 3159
+ V + L+P +Y ++L G Q + + T +P + P
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT-------LQPGSSIP 1092
Query: 3160 EAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTV 3219
P E+T T ++ ++WT P R F + + G V + + V
Sbjct: 1093 -----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 3220 GGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTP----LPVEPRLGELAVA---AVT 3272
GL PG +Y + L +GQ + PL P L P G L V+ + T
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 3273 SDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQ 3332
D G T QG V D + L P +Y ++ ++
Sbjct: 1201 PDITGYRITTTPT---------NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
Query: 3333 NGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEG-EFDSFVVQYKDKD 3391
+ K VP+ P P +L T+ PD++ ++W P + +F+V+Y
Sbjct: 1252 DDKES--VPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS--- 1303
Query: 3392 GRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISA---DSTTAPLEKELPP 3448
PV N+ +V + PS L L G + + +S+ + PL
Sbjct: 1304 ------PVK-NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
Query: 3449 HLGELT---VAEETSSSLRLSWTVAQGPFDSFVVQYRDT--DGQPRAVPVAADQRTVTVE 3503
L T ++ T++S + W + + +++ G+PR V + ++T+
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 3504 DLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVT 3563
+L PG +Y + L G+ P+ +G + D P L V
Sbjct: 1417 NLTPGTEYVVSIVAL-NGREESPL-LIGQQSTVSDVPRD-----------------LEVV 1457
Query: 3564 DTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFL 3621
TP S+ +SW + + Y +T G Q V G +S ISGL+P Y
Sbjct: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
Query: 3622 LYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFD 3681
+Y + G+ P S++ + +E +P SQ+ VTDV +S+ + W
Sbjct: 1518 VYAV-TGRGDSPASSKPIS----INYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVT 1570
Query: 3682 SFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKAD 3741
+ + T P P + + + L+ Y +++Y ++
Sbjct: 1571 GYRV--------TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 3742 SIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQ 3800
+ TA T P +P DL+F+++ TS W PP + ++V + P + +
Sbjct: 1623 PLVQTAVTTIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1679
Query: 3801 VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGF 3858
+ + + + GL+ +YEV+V +++ S P G +TT+ + P + R + TE
Sbjct: 1680 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1739
Query: 3859 AVLHWKPPQNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGP 3917
+ W+ + + V V A G P+Q Y + L T+Y + L
Sbjct: 1740 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1799
Query: 3918 NLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL- 3976
+SP I +T ++AP +L TP + L++W P R GY++ + PG +E++
Sbjct: 1800 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 1859
Query: 3977 -LPGGITSHQLLGLFPSTSYNARLQAM 4002
G+T + GL P T Y + A+
Sbjct: 1860 RPRPGVTEATITGLEPGTEYTIYVIAL 1886
Score = 275 bits (703), Expect = 7e-73
Identities = 321/1498 (21%), Positives = 561/1498 (37%), Gaps = 249/1498 (16%)
Query: 1790 NSVGLSWTVPE-GQFDSFVVQYKDRD--GQPQVVPVEGSLREVSVPGLDPAHRYKLLLYG 1846
NS + W P+ ++++++ ++ G+ + + G L ++ GL P Y+ L
Sbjct: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
Query: 1847 LHH--GKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVT 1904
+ + V + T T T P +V E T+ + +SW+
Sbjct: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
Query: 1905 EGEFDSFEIQY--TDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFS-DGKHVGPV 1961
F ++Y ++ + Q + + + + L +Y+V +Y S DG+ +
Sbjct: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
Query: 1962 HVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY 2021
T P+ A P+P TV S+ + W+ P+ + + Y
Sbjct: 804 STSQTTAPD---------APPDP---------TVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Query: 2022 RNG-DGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETP 2080
+G + +P VT+S L+P +Y + +Y Q PV + +E T
Sbjct: 846 SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-----QQETTG 900
Query: 2081 SPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQG-----RFDSFTVQYKDRDGR 2135
+P ++ +P + + ++ VT + WT P+ R D V G+
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
Query: 2136 PQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKL 2195
+ + V GL PG Y ++ + GR P+ TA + DAP
Sbjct: 953 RLPI---SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPL-----TAQQTTKLDAPT--- 1001
Query: 2196 RLGQMTVRDITSDSLSLSWTVPEGQFDHF-LVQFKNGDGQPKAVRVPGHEDGVTISGLEP 2254
+ + T ++ + WT P Q + L GQP+ V + L+P
Sbjct: 1002 ---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
Query: 2255 DHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDA 2314
+Y ++L G Q + V T + P S+ PP T+
Sbjct: 1059 ASEYTVSLVAIKGNQESPKATGVFTT-------LQPGSSIPPYN-------------TEV 1098
Query: 2315 TPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
T ++ ++WT P + F + + G V + +SGL P +Y +
Sbjct: 1099 TETTIVITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL 1156
Query: 2375 HGGQ-RVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVT---GSSPDSLSLS 2430
GQ R P+ VT PT +EA P G LTV+ ++PD
Sbjct: 1157 RDGQERDAPIVNKVVTPLSP----PTNLHLEA-----NPDTGVLTVSWERSTTPDITGYR 1207
Query: 2431 WTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGP 2490
T T + G V ++S T L PG +Y + +Y + + + P
Sbjct: 1208 IT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 2491 VSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG-RF 2549
+S + A P PT+ L T PD++ ++W P
Sbjct: 1259 ISDTIIPA-------VPPPTD----------------LRFTNIGPDTMRVTWAPPPSIDL 1295
Query: 2550 DSFTVQYKDRDGRPQAVR--VGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGV 2607
+F V+Y + ++ V + L PG +Y + + ++E P+
Sbjct: 1296 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1355
Query: 2608 TEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYR--NG 2665
T ++ T + +D T +S ++ W P + +++ +
Sbjct: 1356 TGLDSPTG------------------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHF 1397
Query: 2666 DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTE 2725
G+P+ RVP + +T++ L P +Y +++ +G EE+P
Sbjct: 1398 SGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---------------REESPLLIG 1442
Query: 2726 LSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMR--VR 2783
+ + P + L V ++P SL +SW P + + Y + G V V
Sbjct: 1443 QQSTVSDVPRD-----LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVP 1497
Query: 2784 GEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKP 2843
G +S T+ GL+PG Y + +Y + GR P S+ ++ + +KP
Sbjct: 1498 GSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYRTEI-----------DKP 1545
Query: 2844 RLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKVVRVPGHEDGVTISGLE 2901
++ VTD +S+S+ W+ + V +NG G K + +TI GL+
Sbjct: 1546 --SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
Query: 2902 PDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGS 2961
P +Y +++Y + P+ VT PAPT+ L T
Sbjct: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTTI----PAPTD----------------LKFTQV 1643
Query: 2962 SPDSLSLSWTIPQGRFDSFTVQY--KDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLY 3019
+P SLS WT P + + V+ K++ G + + + + S V V GL KY++ +Y
Sbjct: 1644 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1703
Query: 3020 GLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWM 3079
L + P V T PP + R VTDAT ++++SW
Sbjct: 1704 ALKDTLTSRPAQGVVTTLEN-------------VSPPRRAR-----VTDATETTITISWR 1745
Query: 3080 VPEGQFDHFLVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPV 3138
F V +GQ R + TI+GL+P YK+ LY + R PV
Sbjct: 1746 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805
Query: 3139 SAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY 3198
T + PS L ++P+SL +SW P+ R + ++Y
Sbjct: 1806 VIDASTAIDAPS------------------NLRFLATTPNSLLVSWQPPRARITGYIIKY 1847
Query: 3199 KDRDGQPQVV--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
+ P+ V R R +E T+ GLEPG +Y +++ L Q+ P+ T LP
Sbjct: 1848 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1905
Score = 268 bits (685), Expect = 9e-71
Identities = 382/1749 (21%), Positives = 660/1749 (37%), Gaps = 299/1749 (17%)
Query: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181
G +Y+ YG +G+ PL Q+ PS P + + T P+S + W
Sbjct: 582 GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
Query: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237
P+ +++++R ++ GR + + G S+ + L P Y L I ++YG
Sbjct: 633 PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
Query: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290
T T+ P PL+ +VT +T S +SW A
Sbjct: 690 QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
Query: 1291 FMVQYK--DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348
F V+Y+ + +PQ + + V +P L P RKY +N+Y + G +S++ T+
Sbjct: 750 FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
Query: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408
T AP++P +P + ++ T S+ + W+ PQ + + Y
Sbjct: 807 Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
Query: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467
+G + + + VT+ L+PG +Y + +Y + E Q PV Q+ET
Sbjct: 848 SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
Query: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524
S P +L +VT V + WT PE + ++ Q +P++ +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583
EVT L P Y ++ + G+ PL+ A + +K L +
Sbjct: 961 FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
Query: 1584 TVTDITPDSVGLSWTVPEGEFDSF-VVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642
TD T V + WT P + + + R GQP+ V + + +L+P+ +Y
Sbjct: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
Query: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701
L I+ G + SP + T + +S PP + T+ T ++ ++WT P F
Sbjct: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
Query: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTTE 1760
V + + P+ V S+ V+ L G +Y + + L G++R P+ T
Sbjct: 1116 KLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT- 1172
Query: 1761 ARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW---TVPEGQFDSFVVQYKDRDGQ- 1816
P P L+ T + +SW T P+ + + +GQ
Sbjct: 1173 ------------PLSPPTNLHLEANPDT-GVLTVSWERSTTPD--ITGYRITTTPTNGQQ 1217
Query: 1817 ----PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872
+VV + S + L P Y + +Y + K PIS +T
Sbjct: 1218 GNSLEEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPIS-------------DT 1262
Query: 1873 TAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEG-EFDSFEIQYT--DRDGQLQMVRIGG 1929
P P P +L T+ ++W + +F ++Y+ + + + I
Sbjct: 1263 IIPAVPPPT----DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
Query: 1930 DRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPR 1989
N + L+ L Y+V++ + P+ ++ + PT
Sbjct: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR------GRQKTGLDSPTG--------- 1363
Query: 1990 LGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEP 2047
+ +D T +S ++ W P + +++ + G+P+ RVP +T++ L P
Sbjct: 1364 ---IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
Query: 2048 DHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSS 2107
+Y VS+V + EE P + + + +L V ++
Sbjct: 1421 GTEY--------------VVSIVALNGREE------SPLLIGQQSTVSDVPRDLEVVAAT 1460
Query: 2108 PDSLSLSWTVPQGRFDSFTVQYKDRDGRP--QVVRVGGEESEVTVGGLEPGRKYKMHLYG 2165
P SL +SW P + + Y + G Q V G +S T+ GL+PG Y + +Y
Sbjct: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
Query: 2166 LHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFL 2225
+ GR P S+ ++ D P QM V D+ +S+S+ W +
Sbjct: 1521 V-TGRGDSPASSKPISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
Query: 2226 VQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPG 2283
V KNG G K + +TI GL+P +Y +++Y + P+ +T
Sbjct: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT-- 1631
Query: 2284 KDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGD 2341
PA T +L T TP SLS WT P Q + V+ K
Sbjct: 1632 -----IPAPT--------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
Query: 2342 GQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEP 2401
G K + V +SGL KY++++Y P + T
Sbjct: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT------------ 1720
Query: 2402 SMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2460
+E PP VT ++ ++++SW F V +G+ + R + +
Sbjct: 1721 -LENVSPPR-----RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
Query: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
T+ GL+PG YK++LY L++ R PV TA +AP
Sbjct: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---------------IDAP--- 1816
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV--RVGGQESKVTVR 2578
L ++P+SL +SW P+ R + ++Y+ P+ V R ++ T+
Sbjct: 1817 -----SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871
Query: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
GLEPG +Y +++ L ++ P+ + T +P + P P L
Sbjct: 1872 GLEPGTEYTIYVIALKNNQKSEPLIG-------RKKTDELPQLVTLP--HPNL------- 1915
Query: 2639 ATPDSLSLSWTVPEGQF-DHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
P+ L + TV + F H Y G+G +++PG SG +P +M ++
Sbjct: 1916 HGPEILDVPSTVQKTPFVTH--PGYDTGNG----IQLPG------TSGQQPSVGQQM-IF 1962
Query: 2698 GFHGGQRVGPISVIGVTAAEEETPSPTELSTE-----APEP-------PEEPLLGELTVT 2745
HG +R P P P + E P P P L T
Sbjct: 1963 EEHGFRRTTP-PTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAST 2021
Query: 2746 GSSP-DSLSLSWTIPQGHFD-SFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMH 2803
G ++SW Q + + D P RV G + T+ GL G Y +
Sbjct: 2022 GQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081
Query: 2804 LYGLHEGRR 2812
+ L + +R
Sbjct: 2082 VEALKDQQR 2090
Score = 267 bits (682), Expect = 2e-70
Identities = 338/1555 (21%), Positives = 584/1555 (37%), Gaps = 220/1555 (14%)
Query: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584
+T T S P+S + W PQ + ++++ ++ GR + + G + T++GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641
Y+ L + + G + V+ T T T+T E P P + ++T+ T
Sbjct: 676 VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Query: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698
S +SW F V+Y GD +P+ + +P V I L P KY +N+Y
Sbjct: 734 SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
Query: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758
G S+I T+ T AP+ P +P + ++ T S+ + W+
Sbjct: 793 I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
Query: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
PQ + + Y +G + + + VT+ L+PG +Y + +Y + E + PV
Sbjct: 834 PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
Query: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872
Q T TP P +L + T +++ W PE + D
Sbjct: 893 ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
Query: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931
V GQ R+P ++GL P Y ++ G+ P++ T +
Sbjct: 943 PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
Query: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990
APT L + ++ + WT P+ + + + R G+
Sbjct: 999 ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
Query: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050
P+ V S+ + L+P +Y VS V + ++ + T T
Sbjct: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
Query: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110
+ P I P E+T T ++ ++W P + F + R G V
Sbjct: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
Query: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167
+ +SGL P +Y + GQ R P+ V + TP PT EA P
Sbjct: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
Query: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224
G LTV+ ++PD T T + G V ++S T L P
Sbjct: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
Query: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
G +Y + +Y + + + P+S T +P P +L + D++ ++W
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
Query: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
+FLV+Y + + + +S AV ++ L P +Y + + P+
Sbjct: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
Query: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399
+T D+ + +D T +S + W P + +++ + GR + V
Sbjct: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
Query: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459
++ +T+ L P +Y + L+GR+ + +T ++P +L V T
Sbjct: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
Query: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517
+SL +SW + + Y +T G + V + T T+ L+PG Y +Y
Sbjct: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
Query: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577
+ G D+PA E + + VTD +S+ + W +
Sbjct: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
Query: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635
P + V NG P G DQ+++ I GL+P+ Y +Y + PL
Sbjct: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
Query: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695
QT+ + P + L T VT +SL W P + +R +
Sbjct: 1626 -----------QTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------V 1666
Query: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755
P + +E+ + S V+ L T Y +++Y L+ + QG TL V
Sbjct: 1667 TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-S 1725
Query: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIP 3815
PR + ++ ET+ ++W F+V A+G P + R+ + GL P
Sbjct: 1726 PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP 1785
Query: 3816 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 3875
G Y++ + ++ S P+ +T D P+ LR L T ++ W+PP+ + Y +
Sbjct: 1786 GTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYII 1845
Query: 3876 QVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT--- 3929
+ PG+PP + PG + + L T YT V L+ + P T
Sbjct: 1846 KYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904
Query: 3930 ---------GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGG 3980
L P L+ +T +T H I LPG
Sbjct: 1905 PQLVTLPHPNLHGPEILDVPSTVQKTPFVT---------------HPGYDTGNGIQLPG- 1948
Query: 3981 ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNG 4035
TS G PS + + PP + + R P+P + GEE+Q G
Sbjct: 1949 -TS----GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR-PYPPNVGEEIQIG 1997
Score = 262 bits (669), Expect = 6e-69
Identities = 369/1720 (21%), Positives = 630/1720 (36%), Gaps = 307/1720 (17%)
Query: 1583 LTVTDITPDSVGLSWTVPE-GEFDSFVVQYKDRD--GQPQVVPVAADQREVTIPDLEPSR 1639
+T T P+S + W P+ ++++++ ++ G+ + + TI L+P
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 1640 KYKFLLFGIQ----------DGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDS 1689
Y+ L IQ D S + G+ +P +P VT+ T S
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 1690 LRLSWTVPEGQFDSFVVQFK---DKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLG 1746
+SW F V+++ + D PQ + + SV + L GRKY +Y +
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 1747 KKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSF 1806
+ + T A A PP P + + V S+ + W+ P+ +
Sbjct: 796 DGEQSLILSTSQTTAPDA--------PPDPTVDQ------VDDTSIVVRWSRPQAPITGY 841
Query: 1807 VVQYKDR-DGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGR 1865
+ Y +G + + + V++ L P +Y + +Y + + P+ T G
Sbjct: 842 RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT 901
Query: 1866 EETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWM-----VTEGEFDSFEIQYTDRDG 1920
++T P P +L E T + + W VT D + G
Sbjct: 902 PRSDT--------VPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
Query: 1921 QLQMVRIGGDRNDIT-LSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPT 1979
Q R+ RN ++GL Y ++ S G+ P LT + K P
Sbjct: 952 Q----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----LTAQQTTKLDAPTN 1002
Query: 1980 ATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAVRVPGHEE 2038
L + T ++ + WT P Q + L GQP+ V
Sbjct: 1003 -------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
Query: 2039 GVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLL 2098
+ L+P +Y ++L G Q + V T +P P P
Sbjct: 1050 KYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL---------QPGSSIP-----PYN 1095
Query: 2099 GELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2158
E+T T ++ ++WT P R F + + G V + + V GL PG +
Sbjct: 1096 TEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
Query: 2159 YKMHLYGLHEGR-RVGPVSAVGVTAPE-------EESPDAPLAKLRLGQMTVRDITSDSL 2210
Y + L +G+ R P+ VT E +PD + + + T DIT
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG--Y 1206
Query: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270
++ T GQ + L + + D + T L P +Y +++Y +
Sbjct: 1207 RITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 2271 VGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEG-Q 2329
P+S + + PA PPT +L T+ PD++ ++W P
Sbjct: 1256 SVPIS----------DTIIPA-VPPPT----------DLRFTNIGPDTMRVTWAPPPSID 1294
Query: 2330 FDHFLVQY---KNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAI 2386
+FLV+Y KN + + + P ++ V ++ L P +Y VS
Sbjct: 1295 LTNFLVRYSPVKNEEDVAELSISPS-DNAVVLTNLLPGTEYV--------------VSVS 1339
Query: 2387 GVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK 2446
V E TP P + + + +S ++ W P+ + +++
Sbjct: 1340 SVYEQHESTPLRGRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITGYRIRHH 1393
Query: 2447 DR--DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVD 2504
GRP+ RV + +T+ L PG +Y + + L+ GR P+ + Q V
Sbjct: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL----LIGQQSTVS 1448
Query: 2505 ETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRP- 2563
+ P +L V ++P SL +SW P + + Y + G
Sbjct: 1449 DVPR------------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
Query: 2564 -QAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMT 2622
Q V G +S T+ GL+PG Y + +Y + GR P S+ ++ +
Sbjct: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISINYRTEID------ 1543
Query: 2623 PEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDG 2680
KP ++ +TD +S+S+ W + V +NG G K +
Sbjct: 1544 -----KP--SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
Query: 2681 VTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLG 2740
+TI GL+P +Y +++Y + P+ VT P+PT+L
Sbjct: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTI----PAPTDLK------------- 1639
Query: 2741 ELTVTGSSPDSLSLSWTIPQGHFDSFTVQY--KDRDGRPQVMRVRGEESEVTVGGLEPGR 2798
T +P SLS WT P + V+ K++ G + + + + S V V GL
Sbjct: 1640 ---FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1696
Query: 2799 KYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSL 2858
KY++ +Y L + P V T + PP + R VTDAT ++
Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVS-----------PPRRAR-----VTDATETTI 1740
Query: 2859 SLSWMVPEGQFDHFLVQYRNGDGQPKVVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2917
++SW F V +GQ + R + TI+GL+P YK+ LY +
Sbjct: 1741 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1800
Query: 2918 RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRF 2977
R P+ + TA + AP+ L ++P+SL +SW P+ R
Sbjct: 1801 RSSPVVIDASTAID----APSN----------------LRFLATTPNSLLVSWQPPRARI 1840
Query: 2978 DSFTVQYKDRDGRPQVV--RVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGV 3035
+ ++Y+ P+ V R R +E T+ GLEPG +Y +++ L Q+ P+
Sbjct: 1841 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG--- 1897
Query: 3036 TAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG 3095
+ T +P + P P L + D ++ G Y G
Sbjct: 1898 ------RKKTDELPQLVTLP--HPNLHGPEILDVPSTVQKTPFVTHPG--------YDTG 1941
Query: 3096 DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR-VGPVSAIGVTEEETPSPTEP 3154
+G +++PG SG +P +M ++ HG +R P +A + P P
Sbjct: 1942 NG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTPPTTATPIRHRPRPYPPNV 1990
Query: 3155 STEAPEA------------PEEPLLGELTVTGSSP-DSLSLSWTVPQGRFD-SFTVQYKD 3200
E P P L TG ++SW Q + +
Sbjct: 1991 GEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVG 2050
Query: 3201 RDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQR 3240
D +P RV G + T+ GL G Y + + L + QR
Sbjct: 2051 TDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
Score = 243 bits (621), Expect = 2e-63
Identities = 353/1584 (22%), Positives = 602/1584 (38%), Gaps = 267/1584 (16%)
Query: 979 VVWTAQPDTFAYFQLRMRVPE-GPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGG 1037
V W + DT + F++ + E G LP +P PG Y ++++ + G
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
Query: 1038 KPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK 1097
+ S + +++ P + TV S+++RW+ P+ + I Y
Sbjct: 798 EQSLIL-----------STSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
Query: 1098 DR-DGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKIL--PQSDP 1154
+G + + S ++ L PG +Y +Y + P+V + + P+SD
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 1155 SPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFV- 1213
P +P L + VTD + + WT PE + V D P +P E +R +
Sbjct: 907 VP-SPRDLQFVEVTDV---KVTIMWTPPESAVTGYRV-----DVIPVNLPGEHGQRLPIS 957
Query: 1214 ------VSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267
V+ L P Y F +F +++ + PLTA TT + + P +F+ +
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT---KLDAPTNLQFVNE------ 1008
Query: 1268 TVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVPGLDPDRKYK 1326
T ++ + WT + + + +GQP+ V ++ + L P +Y
Sbjct: 1009 -----TDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
Query: 1327 MNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEA-PESPEEPLLGELTVTGSSP 1385
++L ++G Q E+P T + T P S P E+T T
Sbjct: 1064 VSLVAIKGNQ------------------ESPKATGVFTTLQPGSSIPPYNTEVTET---- 1101
Query: 1386 DSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHE 1445
++ + WT F + + G V + V GL PG +Y + L +
Sbjct: 1102 -TIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
Query: 1446 GQ-RVGPVSAVGVTAPQQEETPPATESPLE--PRLGELTVT---DVTPNSVG--LSWTVP 1497
GQ R P+ VT P T LE P G LTV+ TP+ G ++ T
Sbjct: 1159 GQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
Query: 1498 EGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVV 1557
GQ G V ADQ T NL P +Y +++Y + D + P+S
Sbjct: 1214 NGQ-----------QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT 1262
Query: 1558 IVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDG 1616
I+ A PP +L T+I PD++ ++W P + +F+V+Y
Sbjct: 1263 IIPAVPPPT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307
Query: 1617 QPQV--VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAP 1674
+ V + ++ V + +L P +Y + + + +P+ KT G SP
Sbjct: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG- 1363
Query: 1675 PRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKD---GPQVVPVEGHERSVTVTPL 1731
+ +D T +S + W P + ++ + P+ V S+T+T L
Sbjct: 1364 -----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
Query: 1732 DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNS 1791
G +Y + L G++ L +S + D PR +L+V T S
Sbjct: 1419 TPGTEYVVSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTS 1463
Query: 1792 VGLSWTVPEGQFDSFVVQYKDRDGQPQV--VPVEGSLREVSVPGLDPAHRYKLLLYGLHH 1849
+ +SW P + + Y + G V V GS ++ GL P Y + +Y +
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT- 1522
Query: 1850 GKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD 1909
G+ P S+ I+ TE P+ ++ V + +++ + W+ +
Sbjct: 1523 GRGDSPASSKPISINYR---TEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVT 1570
Query: 1910 SFEIQYTDRDGQ--LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALT 1967
+ + T ++G + G D+ ++T+ GL+ Y+V++Y + P+ A+T
Sbjct: 1571 GYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
Query: 1968 VPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGD 2025
P P +L T TP SLS WT P Q + V+ +
Sbjct: 1631 T------------IPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1672
Query: 2026 GQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEP 2085
G K + + V +SGL KY++++Y P V VT E +P
Sbjct: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP----- 1726
Query: 2086 SMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGE 2144
P A VT ++ ++++SW F V +G+ + R + +
Sbjct: 1727 ----PRRAR--------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1774
Query: 2145 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRD 2204
T+ GL+PG YK++LY L++ R PV TA DAP +
Sbjct: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLA 1823
Query: 2205 ITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMN 2261
T +SL +SW P + ++++++ P+ V VP GV TI+GLEP +Y +
Sbjct: 1824 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIY 1882
Query: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSL 2321
+ Q+ P L K +E+ T P P L P+ L +
Sbjct: 1883 VIALKNNQKSEP-----LIGRKKTDELPQLVTLP-------HPNLH-------GPEILDV 1923
Query: 2322 SWTVPEGQF-DHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR- 2379
TV + F H Y G+G ++PG SG +P +M ++ HG +R
Sbjct: 1924 PSTVQKTPFVTH--PGYDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRT 1970
Query: 2380 VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEE----------PLLGELTVTGSSP-DSLS 2428
P +A + P ++ P E P L TG +
Sbjct: 1971 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2030
Query: 2429 LSWTVPQGRFD-SFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRR 2487
+SW Q + + D P RV G + T+ GL G Y + + L + +R
Sbjct: 2031 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
Query: 2488 ---------VGPVSTVGVTAPQED 2502
VG G+ P +D
Sbjct: 2091 HKVREEVVTVGNSVNEGLNQPTDD 2114
Score = 242 bits (617), Expect = 7e-63
Identities = 361/1676 (21%), Positives = 626/1676 (37%), Gaps = 278/1676 (16%)
Query: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEY---------- 816
+W P P + Y +++ P A +P ++Y +GL PG Y
Sbjct: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 817 ---QVTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
+VT TS P + T P V +T ++ + W+ V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 868 DRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
F V Y G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
Query: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
G L +L T+ P P P + Q D+T + V W+
Sbjct: 796 DGEQSL-ILSTSQTTAPDAPPD------PTVDQ------------VDDTS-IVVRWSRPQ 835
Query: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE-NQESTPVV 893
Query: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104
Q ++ +S P +L + T + + WT PE + + D P
Sbjct: 894 IQ----QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPV 944
Query: 1105 VVPVEGPQR-------SAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
+P E QR A +T L PG Y F ++ + PL A Q
Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTKLD 998
Query: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY-RDRDGRPQVVPVEGPERSFVVSS 1216
P NL + T ++ + WT P Q + + R G+P+ V + + +
Sbjct: 999 APT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
Query: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
L P +Y +L I + T TT PP T VT +
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTETT 1102
Query: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR-GR 1335
+ ++WT A P F + + +QG V D + V GL P +Y + LR G+
Sbjct: 1103 IVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
Query: 1336 QRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSLSL 1390
+R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1161 ERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDITGY 1206
Query: 1391 FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1207 RIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQYK 1509
P+S + A PP T +L T++ P+++ ++W P +F+V+Y
Sbjct: 1258 PISDTIIPA-----VPPPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
Query: 1510 DKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAP 1567
+ V + ++ V + NL P +Y +++ +++ PL
Sbjct: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL------------- 1350
Query: 1568 ATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAA 1625
K L+ G + +DIT +S + W P + +++ G+P+ V
Sbjct: 1351 -RGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
Query: 1626 DQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685
+ +T+ +L P +Y + + +G+ SP+ + ++ PR +L V
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV------SDVPR--DLEVVAA 1459
Query: 1686 TPDSLRLSWTVPEGQFDSFVVQFKDKDG---PQVVPVEGHERSVTVTPLDAGRKYRFLLY 1742
TP SL +SW P + + + + G Q V G + + T++ L G Y +Y
Sbjct: 1460 TPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1519
Query: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
+ G+ + + R+ +D KP ++QVT V NS+ + W
Sbjct: 1520 AVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSSSP 1568
Query: 1803 FDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
+ V ++G P G E+++ GL P Y + +Y +
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------------ 1616
Query: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT--DR 1918
+G + +T T PAP +L + T +L W + + ++ T ++
Sbjct: 1617 -PSGESQPLVQTAVTTIPAPT----DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK 1671
Query: 1919 DGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPP 1978
G ++ + + D + + +SGL +Y V++Y D LT +P++
Sbjct: 1672 TGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----------TLT----SRPAQGV 1717
Query: 1979 TATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-VPGHE 2037
T E PR VTDAT ++++SW F V +GQ R +
Sbjct: 1718 VTTLENVSPPR--RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV 1775
Query: 2038 EGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPL 2097
TI+GL+P YK+ LY + R PV + TA ++AP
Sbjct: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAP------- 1816
Query: 2098 LGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQ--VVRVGGEESEVTVGGLEP 2155
L ++P+SL +SW P+ R + ++Y+ P+ V R +E T+ GLEP
Sbjct: 1817 -SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1875
Query: 2156 GRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWT 2215
G +Y +++ L ++ P+ +G +E L L + D+ S +
Sbjct: 1876 GTEYTIYVIALKNNQKSEPL--IGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 1933
Query: 2216 VPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVS 2275
G + G+G +++PG SG +P +M ++ HG +R P +
Sbjct: 1934 THPG--------YDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTPPT 1974
Query: 2276 AVGLT-------APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDAT-PDSLS---LSWT 2324
P EE+ + + P L +T ++LS +SW
Sbjct: 1975 TATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWA 2034
Query: 2325 VPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
+ ++ + + G D +P RVPG T++GL Y + + QR
Sbjct: 2035 PFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090
Score = 240 bits (612), Expect = 2e-62
Identities = 309/1457 (21%), Positives = 559/1457 (38%), Gaps = 211/1457 (14%)
Query: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
Query: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Y+ L YG E R +T + P T T P PL+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Query: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
Query: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Query: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
Query: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
Query: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
T+ +A T L + T ++ + W P Q + L
Sbjct: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
Query: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
Query: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
Query: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
Query: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
Query: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
L P +Y +++Y + P+S + P PT+ L T
Sbjct: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA--VPPPTD----------------LRFT 1276
Query: 3174 GSSPDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKM 3230
PD++ ++W P +F V+Y + V + ++ V + L PG +Y +
Sbjct: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
Query: 3231 HLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSF 3290
+ ++E P+ T L +P ++ + +T++S + W + +
Sbjct: 1337 SVSSVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGY 1388
Query: 3291 LVQYRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAP 3348
+++ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV 1447
Query: 3349 DTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREV 3406
P +L V ATP S+ +SW P + + Y + G +Q V ++
Sbjct: 1448 SDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
Query: 3407 TVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLS 3466
T+ GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ +
Sbjct: 1504 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
Query: 3467 WTVAQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRL 3524
W + P + V ++ G + DQ +T+E L+P +Y
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV------------ 1609
Query: 3525 GPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSF 3584
VS E P + A P + L T TP S+ W+ +
Sbjct: 1610 --VSVYAQNPSGESQPLVQTAVTTIPAPTD-----LKFTQVTPTSLSAQWTPPNVQLTGY 1662
Query: 3585 VVQY--EDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL 3642
V+ ++ G + + + D S +++SGL +T Y +Y L + P TT
Sbjct: 1663 RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-- 1720
Query: 3643 APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPL 3702
S PR ++ VTD T +++ ++W F + VP+ + +
Sbjct: 1721 -----LENVSPPRRAR--VTDATETTITISWRTKTETITGFQVD-AVPA------NGQTP 1766
Query: 3703 LQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQF 3762
+QR + P R S + L+ GT Y + LY L ++ + A T +++P +L+F
Sbjct: 1767 IQRTIK-PDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST---AIDAPSNLRF 1821
Query: 3763 SEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK--LQGLIPGARYE 3820
S V+W PP +R + + Y+ G P+ V + + + GL PG Y
Sbjct: 1822 LATTPNSLLVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATITGLEPGTEYT 1880
Query: 3821 VTVVSVRGFEESEPLTG 3837
+ V++++ ++SEPL G
Sbjct: 1881 IYVIALKNNQKSEPLIG 1897
Score = 227 bits (578), Expect = 2e-58
Identities = 301/1392 (21%), Positives = 522/1392 (37%), Gaps = 195/1392 (14%)
Query: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
Query: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
Query: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 919 PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978
A+ G+ T P T+ + ++
Sbjct: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
Query: 979 VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
+ WT P F+L +R +G A EV D +V PG Y ++ + G +
Sbjct: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
Query: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097
PI+ + + P G LTV+ S T P+ +
Sbjct: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
Query: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
+ G V Q S +L PG +Y +Y K P+ P
Sbjct: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
Query: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214
PP +L T+ PD++ ++W P F+V+Y V + + + + V+
Sbjct: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
Query: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
++L P +Y ++ + + PL T L+ P + + +T
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
Query: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332
+S + W + + +++ + G+P+ V N +T+ L P +Y +++ L
Sbjct: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
Query: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392
GR+ SP +G ++ S + +L V ++P SL + W
Sbjct: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
Query: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
P + + + Y + G + V G +S T+ GL+PG Y + +Y + G+
Sbjct: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
Query: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510
P S+ ++ + E + ++ VTDV NS+ + W + V
Sbjct: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
Query: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568
K+ G + DQ E+T+ L+P +Y +++Y + PL VT PAP
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT--IPAPT 1636
Query: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVAAD 1626
+L T +TP S+ WT P + + V+ K++ G + + +A D
Sbjct: 1637 -------------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683
Query: 1627 QREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPT 1686
V + L + KY+ ++ ++D P T+ +PPR VTD T
Sbjct: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN-----VSPPRRAR--VTDAT 1736
Query: 1687 PDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744
++ +SW F V +G P ++ RS T+T L G Y+ LY L
Sbjct: 1737 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
Query: 1745 LGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFD 1804
R P+ D +T A+D L+ T NS+ +SW P +
Sbjct: 1797 NDNARSSPVVIDAST----AID-----------APSNLRFLATTPNSLLVSWQPPRARIT 1841
Query: 1805 SFVVQYKDRDGQP--QVVP-VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861
++++Y ++ G P +VVP + E ++ GL+P Y + + L + ++ P+
Sbjct: 1842 GYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL----- 1895
Query: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFE-IQYTDRDG 1920
GR++T+ T P P H E+ T+ + VT +D+ IQ G
Sbjct: 1896 -IGRKKTDELPQLVTLPHPNLHGPEIL---DVPSTVQKTPFVTHPGYDTGNGIQLPGTSG 1951
Query: 1921 Q-----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPS 1975
Q QM+ T + R+ Y + G+ + H+ V P
Sbjct: 1952 QQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPH 2011
Query: 1976 EP---PTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAV 2031
P P A+ G+ ++ T +SW + ++ + + G D +P
Sbjct: 2012 GPGLNPNAS--------TGQEALSQTT-----ISWAPFQDTSEYIISCHPVGTDEEPLQF 2058
Query: 2032 RVPGHEEGVTISGLEPDHKYKMNLYGFHGGQR---MGPVSVVGVTAAEEETPSPTEPSME 2088
RVPG T++GL Y + + QR V VG + E PT+ S
Sbjct: 2059 RVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCF 2117
Query: 2089 APEPAEEPLLGE 2100
P +G+
Sbjct: 2118 DPYTVSHYAVGD 2129
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 282 bits (722), Expect = 4e-75
Identities = 237/788 (30%), Positives = 305/788 (38%), Gaps = 171/788 (21%)
Query: 126 CPASAQAGTGQTDVRT------LCSLHGVF--DLSRCTCSCEPGWGGPTCSDPTDAEIPP 177
CP S T + DV LC G ++ C C GP C P +P
Sbjct: 166 CPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPY---VPC 222
Query: 178 SSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC--GWPSCPGD-CQGRGRCVQGV-- 232
S P +G C G V C C PG+TG +C CPG+ C+ G CV GV
Sbjct: 223 SPSPCQNGGT---CRPTGD-VTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT 278
Query: 233 --CVCRAGFSGPDCSQ-----RSCPRGCSQRGRCE----GGRCVCDPGYTGDDCGMR--- 278
C C ++G C++ + P C G C G CVC G+TG+DC
Sbjct: 279 YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD 338
Query: 279 ---------------------SCPRG----------------CSQRGRCE----NGR--C 295
CP G C++ C+ NG+ C
Sbjct: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC 398
Query: 296 VCNPGYTGEDCG--VRSCPRG---CSQRGRCKDG----RCVCDPGYTGEDC--GTRSCPW 344
C GYTG C V C G C G+C + C C GYTG C C
Sbjct: 399 TCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVS 458
Query: 345 D-CGEGGRCVDG----RCVCWPGYTGEDCSTRT---CPRDCRGRGRCEDG----ECICDT 392
+ C C+D +C+C PGY G C T C GRC D +C C T
Sbjct: 459 NPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPT 518
Query: 393 GYSGDDC--GVRSCPG-DCNQRGRCEDG----RCVCWPGYTGTDC--GSRACPRDCRGRG 443
G++G C V C C +C DG CVC GYTGT C C D G
Sbjct: 519 GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578
Query: 444 RCENGV----CVCNAGYSGEDC--GVRSCPGD-CRGRGRCE----SGRCMCWPGYTGRDC 492
C++GV C+C GY+G C + C CR G C+ + C C G TG +C
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Query: 493 GTRA--CPGDCRGRGRCVDG----RCVCNPGFTGEDCGSR--RCPGD-CRGHGLCEDGV- 542
C G C+D C C PG+TG C C G+ C G CEDG+
Sbjct: 639 EINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGIN 698
Query: 543 ---CVCDAGYSGEDC--STRSCPGGCRGRGQCLDG----RCVCEDGYSGEDCGV--RQC- 590
C C GY C C G C D +C C+ G+SG +C + +C
Sbjct: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECE 758
Query: 591 PNDCSQHGVCQD----GVCICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCD 639
N C G C+D VC C EG+ +C +I C SN C +G C + +C C
Sbjct: 759 SNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL 818
Query: 640 PGYTGPTCATRM---CPADCRGRGRCVQG------VCLCHVGYGGEDCGQE--EPPASAC 688
YTG TC + P+ CR G C Q C+C G+ G+ C + E S C
Sbjct: 819 LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPC 878
Query: 689 PGGCGPRELCRAGQCVCVEGFRGPDCA--IQTC-PGDCRGRGECHDG----SCVCKDGYA 741
G + +C C G+ G +C I C P C G C DG C C G+
Sbjct: 879 RHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFR 938
Query: 742 GEDCGEEV 749
G C E++
Sbjct: 939 GTFCEEDI 946
Score = 277 bits (708), Expect = 2e-73
Identities = 227/762 (29%), Positives = 292/762 (38%), Gaps = 157/762 (20%)
Query: 143 CSLHGVFDLSRCT---CSCEPGWGGPTCSD----------------PTDAEIPPSSPPSA 183
C G DL T C C PGW G +C P +A PPS
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSF 170
Query: 184 SG-SCPDDCNDQGR----CVRG----------RCVCFPGYTGPSCG---WPSCPGDCQGR 225
G +C D N+ G+ C G RCVC +TGP+C P P CQ
Sbjct: 171 HGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNG 230
Query: 226 GRC-----VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGG----RCVCDPGYTGD 273
G C V C C GF+G +C + CP C G C G C C P +TG
Sbjct: 231 GTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQ 290
Query: 274 DC--GMRSC---PRGCSQRGRCENG----RCVCNPGYTGEDCGVR-------SCPRGCSQ 317
C + C P C G C N CVC G+TGEDC +C G +
Sbjct: 291 YCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATC 350
Query: 318 RGRCKDGRCVCDPGYTGEDCGTRSC--PWDCGEGGRC----VDGR--CVCWPGYTGEDCS 369
R C C G TG C C EG C V+G+ C C GYTG CS
Sbjct: 351 HDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACS 410
Query: 370 --TRTC---PRDCRGRGRCEDG----ECICDTGYSG-------DDCGVRSCPGDCNQRGR 413
C C G+C + EC C GY+G ++C C D +
Sbjct: 411 QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQ 470
Query: 414 CEDGRCVCWPGYTGTDC---GSRACPRDCRGRGRCENGV----CVCNAGYSGEDC--GVR 464
+ +C+C PGY G C C GRC + + C C G++G C V
Sbjct: 471 IGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVD 530
Query: 465 SCPG-DCRGRGRCESG----RCMCWPGYTGRDC--GTRACPGDCRGRGRCVDG----RCV 513
C C+ +C G C+C GYTG C C D G C DG C+
Sbjct: 531 ECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCL 590
Query: 514 CNPGFTGEDCGS--RRCPGD-CRGHGLCEDG----VCVCDAGYSGEDCSTR--SCPGGCR 564
C PG+TG C + C CR G C+D +C C G +G +C C
Sbjct: 591 CRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPC 650
Query: 565 GRGQCLDG----RCVCEDGYSGEDCGVR--QCP-NDCSQHGVCQDGV----CICWEGYVS 613
G CLD C CE GY+G C + +C N C G C+DG+ C C EGY
Sbjct: 651 DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHD 710
Query: 614 EDC--SIRTCPSNCHGRGRCEEG----RCLCDPGYTGPTC--ATRMCPAD-CRGRGRCVQ 664
C + C SN G C + +C CDPG++G C C ++ C G C
Sbjct: 711 PTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD 770
Query: 665 ----GVCLCHVGYGGEDCGQEEPPASACPGGCGPRELC----RAGQCVCVEGFRGPDCAI 716
VC C G+ G +C ++ P C + C +C C+ + G C +
Sbjct: 771 MTSGYVCTCREGFSGPNCQTNINECASNP--CLNQGTCIDDVAGYKCNCLLPYTGATCEV 828
Query: 717 ---QTCPGDCRGRGECHDG------SCVCKDGYAGEDCGEEV 749
P CR GEC SCVC G+ G+ C ++
Sbjct: 829 VLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDI 870
Score = 266 bits (679), Expect = 4e-70
Identities = 209/717 (29%), Positives = 282/717 (39%), Gaps = 129/717 (17%)
Query: 153 RCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG----RCVCFPGY 208
+ C+C G+ GP CS D ++P C G+C+ C C GY
Sbjct: 395 KAICTCPSGYTGPACSQDVDECSLGANP----------CEHAGKCINTLGSFECQCLQGY 444
Query: 209 TGPSCGWP--SCPGD-CQGRGRCVQGV----CVCRAGFSGPDC---SQRSCPRGCSQRGR 258
TGP C C + CQ C+ + C+C G+ G C + C GR
Sbjct: 445 TGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGR 504
Query: 259 C----EGGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC- 306
C +C C G+TG D+C C G CVC GYTG C
Sbjct: 505 CLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Query: 307 -GVRSCPRGCSQRGRCKDG----RCVCDPGYTGEDCGT---RSCPWDCGEGGRCVDG--- 355
+ C G CKDG C+C PGYTG C T C GG C D
Sbjct: 565 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNA 624
Query: 356 -RCVCWPGYTGEDCSTR--TCPRDCRGRGRCEDG----ECICDTGYSGDDCGVR--SCPG 406
C C G TG +C C G C D EC C+ GY+G C + C G
Sbjct: 625 YLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAG 684
Query: 407 D-CNQRGRCEDG----RCVCWPGYTGTDCGSRA--CPRDCRGRGRCENGV----CVCNAG 455
+ C+ G CEDG C C GY C S C + G C + + C C+ G
Sbjct: 685 NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744
Query: 456 YSGEDCGVRS--CPGD-CRGRGRCE---SGR-CMCWPGYTGRDCGT---RACPGDCRGRG 505
+SG +C + + C + C G C+ SG C C G++G +C T C +G
Sbjct: 745 WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804
Query: 506 RCVDG----RCVCNPGFTGEDCG---SRRCPGDCRGHGLC------EDGVCVCDAGYSGE 552
C+D +C C +TG C + P CR G C E CVC G+ G+
Sbjct: 805 TCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQ 864
Query: 553 DCST--RSCP-GGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQD 602
C C CR C + RC C+ GYSG +C + C PN C G C D
Sbjct: 865 TCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD 924
Query: 603 GV----CICWEGYVSEDC--SIRTCPSN-CHGRGRC----EEGRCLCDPGYTGPTCATR- 650
G+ C C G+ C I C S+ C C + C C G++G C
Sbjct: 925 GINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT 984
Query: 651 --MCPADCRGRGRCVQGV----CLCHVGYGGEDCGQE--EPPASACPGGCGPRELCRAGQ 702
+ C G CV G+ CLC G+ G C + E + C G ++ C + +
Sbjct: 985 PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYR 1044
Query: 703 CVCVEGFRGPDC--AIQTCPGD-CRGRGECHDG----SCVCKDGYAGEDCGEEVPTI 752
C C +G+ GP+C + C C+ G+C C C G+ G C +VP++
Sbjct: 1045 CTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC--DVPSV 1099
Score = 263 bits (673), Expect = 2e-69
Identities = 216/748 (28%), Positives = 282/748 (37%), Gaps = 166/748 (22%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
CSC G+ GP C P D ++P G+C D +C C PG++G SC
Sbjct: 87 CSCALGFSGPLCLTPLD-NACLTNPCRNGGTC-----DLLTLTEYKCRCPPGWSGKSCQQ 140
Query: 214 GWPSCPGDCQGRGRCV----QGVCVCRAGFSGPDCSQ--RSC---PRGCSQRGRCEGG-- 262
P C G+C+ +C C F GP C Q C P C G C
Sbjct: 141 ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVG 200
Query: 263 --RCVCDPGYTGDDCG---MRSCPRGCSQRGRCE-----NGRCVCNPGYTGEDC--GVRS 310
RCVC +TG +C + P C G C C C PG+TG++C +
Sbjct: 201 SYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDD 260
Query: 311 CP-RGCSQRGRCKDG----RCVCDPGYTGEDC-----GTRSCPWDCGEGGRCVDG----R 356
CP C G C DG C C P +TG+ C + P C GG C +
Sbjct: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYN 320
Query: 357 CVCWPGYTGEDCSTR------------------------TCPRDCRG----------RGR 382
CVC G+TGEDCS CP G
Sbjct: 321 CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
Query: 383 CEDGE------------CICDTGYSG-------DDCGVRSCPGDCNQRGRCEDG----RC 419
C +G C C +GY+G D+C + + P C G+C + C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANP--CEHAGKCINTLGSFEC 438
Query: 420 VCWPGYTG-------TDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRS---CPGD 469
C GYTG +C S C D + C+C GY G C V +
Sbjct: 439 QCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSP 498
Query: 470 CRGRGRC----ESGRCMCWPGYTGRDCG---TRACPGDCRGRGRCVDG----RCVCNPGF 518
C GRC +C C G+TG C C+ +C+DG CVC G+
Sbjct: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY 558
Query: 519 TGEDC--GSRRCPGDCRGHGLCEDGV----CVCDAGYSGEDCST--RSCPG-GCRGRGQC 569
TG C C D +G C+DGV C+C GY+G C T C CR G C
Sbjct: 559 TGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTC 618
Query: 570 LDG----RCVCEDGYSGEDCGVR--QCPNDCSQHGVCQDGV----CICWEGYVSEDCSIR 619
D C C G +G +C + C + G C D + C C GY C+I
Sbjct: 619 QDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNIN 678
Query: 620 --TCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM--CPADCRGRGRCVQGV---- 666
C N CH G CE+G C C GY PTC + + C ++ G C +
Sbjct: 679 IDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYK 738
Query: 667 CLCHVGYGGEDC--GQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCA--IQTCPGD 722
C C G+ G +C E ++ C G +++ C C EGF GP+C I C +
Sbjct: 739 CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN 798
Query: 723 -CRGRGECHDG----SCVCKDGYAGEDC 745
C +G C D C C Y G C
Sbjct: 799 PCLNQGTCIDDVAGYKCNCLLPYTGATC 826
Score = 256 bits (653), Expect = 4e-67
Identities = 213/747 (28%), Positives = 297/747 (39%), Gaps = 139/747 (18%)
Query: 127 PASAQAGTGQTDVRTLCSLHGVFDLSRCT--CSCEPGWGGPTCSDPTDAEIPPSSPPSAS 184
PA A G + C G + + T C C + GP C DP S+P +
Sbjct: 15 PALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPC---LSTPCKNA 71
Query: 185 GSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP---SC-PGDCQGRGRC-----VQGVCVC 235
G+C D+ C C G++GP C P +C C+ G C + C C
Sbjct: 72 GTC--HVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC 129
Query: 236 RAGFSGPDCSQRS--CPRGCSQRGRC----EGGRCVCDPGYTG-------DDCGMRSCPR 282
G+SG C Q C+ G+C C C P + G ++CG + P
Sbjct: 130 PPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK--PG 187
Query: 283 GCSQRGRCENG----RCVCNPGYTGEDCG---VRSCPRGCSQRGRCK-----DGRCVCDP 330
C G C N RCVC +TG +C V P C G C+ C C P
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 331 GYTGEDC--GTRSCPW-DCGEGGRCVDG----RCVCWPGYTGEDCS-----TRTCPRDCR 378
G+TG++C CP +C GG CVDG C C P +TG+ C+ + P C+
Sbjct: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Query: 379 GRGRCEDG----ECICDTGYSGDDC--GVRSC-PGDCNQRGRCEDG----RCVCWPGYTG 427
G C + C+C G++G+DC + C C C D C C G TG
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTG 367
Query: 428 TDCG-SRAC-PRDCRGRGRCE----NG--VCVCNAGYSGEDCG--VRSC---PGDCRGRG 474
C + AC C C+ NG +C C +GY+G C V C C G
Sbjct: 368 LLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAG 427
Query: 475 RC----ESGRCMCWPGYTG-------RDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDC 523
+C S C C GYTG +C + C D + + +C+C PG+ G C
Sbjct: 428 KCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
Query: 524 --GSRRCPGD-CRGHGLCEDGV----CVCDAGYSG-------EDCSTRSCPGGCRGRGQC 569
+ C C +G C D + C C G++G ++C++ C G + C
Sbjct: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK----C 543
Query: 570 LDG----RCVCEDGYSGEDC--GVRQCPNDCSQHGVCQDGV----CICWEGYVSEDC--S 617
LDG CVC +GY+G C + +C D +G C+DGV C+C GY C +
Sbjct: 544 LDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETN 603
Query: 618 IRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM--CPADCRGRGRCVQGV---- 666
I C S C G C++ C C G TGP C + C + G C+ +
Sbjct: 604 INECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYE 663
Query: 667 CLCHVGYGGEDC--GQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDC--AIQTCPGD 722
C C GY G C +E + C G + C C EG+ P C + C +
Sbjct: 664 CACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSN 723
Query: 723 CRGRGECHDG----SCVCKDGYAGEDC 745
G C D C C G++G +C
Sbjct: 724 PCVHGACRDSLNGYKCDCDPGWSGTNC 750
Score = 253 bits (646), Expect = 3e-66
Identities = 218/758 (28%), Positives = 281/758 (37%), Gaps = 175/758 (23%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
C C G+ GP C D S+P +C D + +C+C PGY G C
Sbjct: 438 CQCLQGYTGPRCE--IDVNECVSNPCQNDATCLDQIGEF------QCICMPGYEGVHCEV 489
Query: 214 GWPSCPGD-CQGRGRCVQGV----CVCRAGFSGPDCS---QRSCPRGCSQRGRCEGG--- 262
C C GRC+ + C C GF+G C C +C G
Sbjct: 490 NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNT 549
Query: 263 -RCVCDPGYTGDDC--GMRSCPRGCSQRGRCENG----RCVCNPGYTGEDC--GVRSCP- 312
CVC GYTG C + C G C++G C+C PGYTG C + C
Sbjct: 550 YTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSS 609
Query: 313 RGCSQRGRCKDGR----CVCDPGYTGEDCGTR-----SCPWDCGEGGRCVDG-RCVCWPG 362
+ C G C+D C C G TG +C S P D G +DG C C PG
Sbjct: 610 QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPG 669
Query: 363 YTGEDCSTRT---CPRDCRGRGRCEDG----ECICDTGYSGDDC--GVRSCPGDCNQRGR 413
YTG C+ C G CEDG C C GY C V C + G
Sbjct: 670 YTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
Query: 414 CEDG----RCVCWPGYTGTDC--GSRACPRD-CRGRGRCENG----VCVCNAGYSGEDC- 461
C D +C C PG++GT+C + C + C G C++ VC C G+SG +C
Sbjct: 730 CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ 789
Query: 462 -GVRSCPGD-CRGRGRCESG----RCMCWPGYTGRDCGT---RACPGDCRGRGRCVDGR- 511
+ C + C +G C +C C YTG C P CR G C
Sbjct: 790 TNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED 849
Query: 512 -----CVCNPGFTGEDC--GSRRCP-GDCRGHGLCEDGV----CVCDAGYSGEDCSTR-- 557
CVC G+ G+ C C CR C++ C C AGYSG +C T
Sbjct: 850 YESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDID 909
Query: 558 SC-PGGCRGRGQCLDGR----CVCEDGYSGEDC--GVRQCPND----------------- 593
C P C G C DG C C G+ G C + +C +D
Sbjct: 910 DCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTC 969
Query: 594 ----------------------CSQHGVCQDGV----CICWEGYVSEDCS--IRTCPSN- 624
C G C DG+ C+C G+ C + C S
Sbjct: 970 TCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQP 1029
Query: 625 CHGRGRCEEG----RCLCDPGYTGPTCATRMCPAD---CRGRGRC----VQGVCLCHVGY 673
C G C++G RC C GYTGP C + D C+ G+C Q C C G+
Sbjct: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089
Query: 674 GGEDCGQEEPPASACP-----GGCGPRELCRAG----------QCVCVEGFRGPDCA--I 716
G C + P+ +C G LC+ G C C G+ G C +
Sbjct: 1090 TGLYC---DVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLV 1146
Query: 717 QTC-PGDCRGRGECHDG----SCVCKDGYAGEDCGEEV 749
C P C+ C D SC C GY G +C EE+
Sbjct: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
Score = 251 bits (642), Expect = 8e-66
Identities = 242/885 (27%), Positives = 318/885 (35%), Gaps = 234/885 (26%)
Query: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGLKE------QC----TGGCCPASAQ--- 131
C CP G P + +V + E K + QC TG C
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECV 457
Query: 132 AGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDC 191
+ Q D L + G F C C PG+ G C TD SSP +G C D
Sbjct: 458 SNPCQNDATCLDQI-GEFQ-----CICMPGYEGVHCEVNTDE--CASSPCLHNGRCLDKI 509
Query: 192 NDQGRCVRGRCVCFPGYTGPSCGWP--SCPGD-CQGRGRCVQG----VCVCRAGFSGPDC 244
N+ +C C G+TG C + C C+ +C+ G CVC G++G C
Sbjct: 510 NEF------QCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHC 563
Query: 245 SQR--SCPRGCSQRGRCEGG----RCVCDPGYTG-------DDCGMRSCPRGCSQRGRCE 291
C G C+ G C+C PGYTG ++C + C G + + R
Sbjct: 564 EVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDN 623
Query: 292 NGRCVCNPGYTGEDCGVR--SCPRGCSQRGRCKDG----RCVCDPGYTGEDCGTR--SCP 343
C C G TG +C + C G C D C C+PGYTG C C
Sbjct: 624 AYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECA 683
Query: 344 WD-CGEGGRCVDG-----------------------------------------RCVCWP 361
+ C GG C DG +C C P
Sbjct: 684 GNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDP 743
Query: 362 GYTGEDC--STRTCPRD-CRGRGRCEDGE----CICDTGYSGDDC--GVRSCPGD-CNQR 411
G++G +C + C + C G C+D C C G+SG +C + C + C +
Sbjct: 744 GWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQ 803
Query: 412 GRCEDG----RCVCWPGYTGTDCG---SRACPRDCRGRGRC------ENGVCVCNAGYSG 458
G C D +C C YTG C + P CR G C E+ CVC G+ G
Sbjct: 804 GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQG 863
Query: 459 EDCGV--RSCP-GDCRGRGRCESG----RCMCWPGYTGRDCGTRA--C-PGDCRGRGRCV 508
+ C V C CR C++ RC C GY+GR+C T C P C G C
Sbjct: 864 QTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCT 923
Query: 509 DGR----CVCNPGFTGEDCGS--RRCPGD-CRGHGLCEDGV----CVCDAGYSGEDC--S 555
DG C C PGF G C C D CR C D V C C AG+SG C +
Sbjct: 924 DGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN 983
Query: 556 TRSCP-GGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQCPND-CSQHGVCQDGV--- 604
T C C G C+DG C+C G++G C V +C + C G CQDG
Sbjct: 984 TPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSY 1043
Query: 605 -CICWEGYVSEDCS--IRTCPSN-CHGRGRC----EEGRCLCDPGYTGPTCATRMCPAD- 655
C C +GY +C + C S+ C G+C + RC C G+TG C +
Sbjct: 1044 RCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEV 1103
Query: 656 ------------CRGRGRCVQGV----CLCHVGYGGEDCGQ--EEPPASACPGGCGPREL 697
C+ G CV C C GY G C +E S C G +
Sbjct: 1104 AAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDY 1163
Query: 698 CRAGQCVCVEGFRGPDCAIQ------------------------TCPGDCRG-------- 725
C CV G+ G +C+ + +CP +G
Sbjct: 1164 LGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVD 1223
Query: 726 -----------------RGECHDG----SCVCKDGYAGEDCGEEV 749
G C D SC C G+ GE C +V
Sbjct: 1224 DCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
Score = 242 bits (618), Expect = 5e-63
Identities = 220/739 (29%), Positives = 283/739 (38%), Gaps = 162/739 (21%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG 214
TC C G+ PTC + +S P G+C D N +C C PG++G +C
Sbjct: 701 TCRCPEGYHDPTCLSEVNE---CNSNPCVHGACRDSLNGY------KCDCDPGWSGTNCD 751
Query: 215 WPSCPGDCQGRGRCVQG----------VCVCRAGFSGPDCS---QRSCPRGCSQRGRC-- 259
+ +C+ CV G VC CR GFSGP+C C +G C
Sbjct: 752 INN--NECESNP-CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCID 808
Query: 260 --EGGRCVCDPGYTGDDCGM---RSCPRGCSQRGRC------ENGRCVCNPGYTGEDCGV 308
G +C C YTG C + P C G C E+ CVC G+ G+ C V
Sbjct: 809 DVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEV 868
Query: 309 -------RSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR--SC-PWDCGEGGRCVDGR-- 356
C G S + RC C GY+G +C T C P C GG C DG
Sbjct: 869 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINT 928
Query: 357 --CVCWPGYTGEDCST--RTCPRD-CRGRGRCEDG----ECICDTGYSGDDC--GVRSCP 405
C C PG+ G C C D CR C D C C G+SG C C
Sbjct: 929 AFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCT 988
Query: 406 -GDCNQRGRCEDG----RCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV----CVCN 453
C G C DG C+C PG+TG+ C + + C G C++G C C
Sbjct: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP 1048
Query: 454 AGYSGEDCG--VRSCPGD-CRGRGRC----ESGRCMCWPGYTGRDCGTRACPGD------ 500
GY+G +C V C C+ G+C RC C G+TG C + +
Sbjct: 1049 QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQ 1108
Query: 501 -------CRGRGRCVDG----RCVCNPGFTG---EDCGSRRCPGDCRGHGLCEDGV---- 542
C+ G CVD C C G+TG ED P C+ C D +
Sbjct: 1109 GVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYS 1168
Query: 543 CVCDAGYSGEDCSTR-----SCPGGCRGRGQCLD----GRCVCEDGYSGEDC--GVRQC- 590
C C AGY G +CS S P C+ G CLD +C C G G C V C
Sbjct: 1169 CKCVAGYHGVNCSEEIDECLSHP--CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCN 1226
Query: 591 -PND-------CSQHGVCQDGV----CICWEGYVSEDCS--IRTCPSN-CHGRG------ 629
P D C +G C D V C C G+V E C + C SN C RG
Sbjct: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ 1286
Query: 630 RCEEGRCLCDPGYTGPTCATRM--CPAD-CRGRGRCVQG-------VCLCHVGYGGEDCG 679
R + C C G+TG C + + C C+ G C +C C G+ G C
Sbjct: 1287 RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Query: 680 QEEPPASA--CPGGCGPRELCRAGQCVCVEGFRGPDC---AIQTCPG--DCRGRGECHDG 732
+ + C G R+ C+C+ F GP+C A C G C +G C
Sbjct: 1347 NDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPT 1406
Query: 733 S------CVCKDGYAGEDC 745
S C+C + G C
Sbjct: 1407 SESPFYRCLCPAKFNGLLC 1425
Score = 207 bits (528), Expect = 1e-52
Identities = 197/705 (27%), Positives = 259/705 (36%), Gaps = 147/705 (20%)
Query: 164 GPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPS--CPGD 221
GP CS P + + +A+G+ CVC + GP C P+
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGT-------------EACVCGGAFVGPRCQDPNPCLSTP 67
Query: 222 CQGRGRCV----QGV----CVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGD 273
C+ G C +GV C C GFSGP C C+ +P G
Sbjct: 68 CKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPL------------DNACLTNPCRNGG 115
Query: 274 DCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRS--CPRGCSQRGRCKDGR----CV 327
C + + +C C PG++G+ C C+ G+C C
Sbjct: 116 TCDLLTLTEY----------KCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICH 165
Query: 328 CDPGYTGEDC--GTRSC---PWDCGEGGRCVDG----RCVCWPGYTGEDCS---TRTCPR 375
C P + G C C P C GG C + RCVC +TG +C P
Sbjct: 166 CPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPS 225
Query: 376 DCRGRGRCEDG-----ECICDTGYSGDDC--GVRSCPGD-CNQRGRCEDG----RCVCWP 423
C+ G C EC C G++G +C + CPG+ C G C DG C C P
Sbjct: 226 PCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPP 285
Query: 424 GYTGTDCGS-----RACPRDCRGRGRCENGV----CVCNAGYSGEDCGVR-------SCP 467
+TG C + P C+ G C N CVC G++GEDC +C
Sbjct: 286 EWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACF 345
Query: 468 GDCRGRGRCESGRCMCWPGYTGRDCGTR-ACPGD-CRGRGRC----VDGR--CVCNPGFT 519
R S C C G TG C AC + C C V+G+ C C G+T
Sbjct: 346 HGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT 405
Query: 520 GEDCGSR--RCP---GDCRGHGLCEDGV----CVCDAGYSGEDCS--TRSCPGG-CRGRG 567
G C C C G C + + C C GY+G C C C+
Sbjct: 406 GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDA 465
Query: 568 QCLDG----RCVCEDGYSGEDCGVR--QCPND-CSQHGVCQDGV----CICWEGYVSEDC 616
CLD +C+C GY G C V +C + C +G C D + C C G+ C
Sbjct: 466 TCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLC 525
Query: 617 S--IRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM--CPADCRGRGRCVQGV- 666
+ C S C +C +G C+C GYTG C + C D G C GV
Sbjct: 526 QYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVA 585
Query: 667 ---CLCHVGYGGEDCGQEEPPASACP----GGCGPRELCRAGQCVCVEGFRGPDCAIQT- 718
CLC GY G C S+ P G C R+ A C C++G GP+C I
Sbjct: 586 TFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRD--NAYLCFCLKGTTGPNCEINLD 643
Query: 719 -CPGDCRGRGECHDG----SCVCKDGYAGEDCGEEVPTIEGMRMH 758
C G C D C C+ GY G C + G H
Sbjct: 644 DCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCH 688
Score = 207 bits (527), Expect = 2e-52
Identities = 237/876 (27%), Positives = 304/876 (34%), Gaps = 221/876 (25%)
Query: 85 CGCPPGTEPPVLASEVQALRVRLEI---LEELVKGLKEQCTGGCCPASAQAGTGQTDVRT 141
C CP G P SEV + + + G K C G + + +
Sbjct: 702 CRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNP 761
Query: 142 LCSLHGVFDL-SRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG 200
+ D+ S C+C G+ GP C T+ S+P G+C DD V G
Sbjct: 762 CVNGGTCKDMTSGYVCTCREGFSGPNCQ--TNINECASNPCLNQGTCIDD-------VAG 812
Query: 201 -RCVCFPGYTGPSCGW---PSCPGDCQGRGRCVQGV------CVCRAGFSGP-------D 243
+C C YTG +C P P C+ G C Q CVC G+ G +
Sbjct: 813 YKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINE 872
Query: 244 CSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDC--GMRSC-PRGCSQRGRCENGR----CV 296
C C G S + G RC C GY+G +C + C P C G C +G C
Sbjct: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCD 932
Query: 297 CNPGYTGEDC--GVRSCPRG-CSQRGRCKDG----RCVCDPGYTGEDC--GTRSCPWD-C 346
C PG+ G C + C C C D C C G++G C T C C
Sbjct: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC 992
Query: 347 GEGGRCVDG----RCVCWPGYTGEDCS--TRTCP-RDCRGRGRCEDG----ECICDTGYS 395
GG CVDG C+C PG+TG C C + C G C+DG C C GY+
Sbjct: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT 1052
Query: 396 GDDCG--VRSCPGD-CNQRGRC----EDGRCVCWPGYTGTDCG--SRACP---------- 436
G +C V C C G+C RC C G+TG C S +C
Sbjct: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
Query: 437 -RDCRGRGRCENGV----CVCNAGYSGEDCG--VRSC-PGDCRGRGRCESG----RCMCW 484
R C+ G C + C C AGY+G C V C P C+ C C C
Sbjct: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1172
Query: 485 PGYTGRDCGTR---ACPGDCRGRGRCVD----GRCVCNPGFTG-------EDCGSRRCPG 530
GY G +C C+ G C+D +C C G G +DC P
Sbjct: 1173 AGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPV 1232
Query: 531 D----CRGHGLCEDGV----CVCDAGYSGEDCS-----TRSCPGGCRGRGQCL----DGR 573
C +G C D V C C G+ GE C S P RG C+ D
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFH 1292
Query: 574 CVCEDGYSGEDCG--VRQCPND-CSQHGVC-------QDGVCICWEGYVSEDCS--IRTC 621
C C G++G C + C C G C + +C C G+ C RTC
Sbjct: 1293 CECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTC 1352
Query: 622 PS-NCHGRGRCEEG----RCLCDPGYTGPTCATRMCPADCRGRGRCV-QGVC-------- 667
S C G C G CLC +TGP C + C G C QG C
Sbjct: 1353 GSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFP-ASSPCLGGNPCYNQGTCEPTSESPF 1411
Query: 668 ------------LCHV---GYGGEDCGQEEPPASACPGGCGPRELCRAGQCVC------- 705
LCH+ +GG G++ PP P AG VC
Sbjct: 1412 YRCLCPAKFNGLLCHILDYSFGG-GAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNH 1470
Query: 706 VEGFRGPDCAIQT---------------------CPGDCRGRG------ECH--DGSC-- 734
G+ G DC++ C C G +C +G C
Sbjct: 1471 ACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNP 1530
Query: 735 ----VCKDGYA----------------GEDCGEEVP 750
CKD ++ G DC E VP
Sbjct: 1531 LYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVP 1566
Score = 180 bits (457), Expect = 2e-44
Identities = 198/737 (26%), Positives = 254/737 (34%), Gaps = 157/737 (21%)
Query: 82 STGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTG----QT 137
S C CP G + ++ +L G Q T G QAG +T
Sbjct: 852 SFSCVCPTGWQGQTCEVDINEC-----VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCET 906
Query: 138 DVRTLCSLHGVFDLSRCT-------CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDD 190
D+ C + + CT C C PG+ G C + + +S P +G+ D
Sbjct: 907 DIDD-CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE---CASDPCRNGANCTD 962
Query: 191 CNDQGRCVRGRCVCFPGYTGPSC--GWPSCP-GDCQGRGRCVQGV----CVCRAGFSGP- 242
C D C C G++G C P C C G CV G+ C+C GF+G
Sbjct: 963 CVDSYTCT-----CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSY 1017
Query: 243 ------DCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG--MRSCPRG-CSQRGRC--- 290
+C + C G + + C RC C GYTG +C + C C G+C
Sbjct: 1018 CQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 1077
Query: 291 -ENGRCVCNPGYTGEDCGVRS-------------CPRGCSQRGRCKDG----RCVCDPGY 332
RC C G+TG C V S R C G C D C C GY
Sbjct: 1078 HTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGY 1137
Query: 333 TG---EDCGTRSCPWDCGEGGRCVD----GRCVCWPGYTGEDCS---TRTCPRDCRGRGR 382
TG ED P C G C D C C GY G +CS C+ G
Sbjct: 1138 TGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGT 1197
Query: 383 CED----GECICDTGYSG-------DDCGVRSCP----GDCNQRGRCEDG----RCVCWP 423
C D +C C G G DDC P C G C D C C P
Sbjct: 1198 CLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPP 1257
Query: 424 GYTGTDCGS--RAC---PRDCRGRGRCENGV----CVCNAGYSGEDCG--VRSCPG-DCR 471
G+ G C C P D RG C V C C AG++G C + C G C+
Sbjct: 1258 GFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
Query: 472 GRGRCESGR-------CMCWPGYTGRDC--GTRACPG-DCRGRGRCVDG----RCVCNPG 517
G C C C G+ G C R C C G C+ G C+C
Sbjct: 1318 NGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGP 1377
Query: 518 FTGEDC---GSRRCPG--DCRGHGLCEDGV------CVCDAGYSGEDCSTRSCPGGCRGR 566
FTG +C S C G C G CE C+C A ++G C G G
Sbjct: 1378 FTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFG-GGA 1436
Query: 567 GQCLDGRCV---CEDGYSGEDCGVRQCPNDCSQHGVCQDG----------------VCIC 607
G+ + + CE ED G + C C+ H DG C
Sbjct: 1437 GRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQC 1496
Query: 608 WEGYVSEDCSIRTCPSNCHGRG-RCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGV 666
W+ + C + + C G C+ C+P Y + C D G C QG
Sbjct: 1497 WKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLY------DQYC-KDHFSDGHCDQGC 1549
Query: 667 CLCHVGYGGEDCGQEEP 683
+ G DC + P
Sbjct: 1550 NSAECEWDGLDCAEHVP 1566
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 273 bits (699), Expect = 2e-72
Identities = 264/900 (29%), Positives = 328/900 (36%), Gaps = 213/900 (23%)
Query: 36 APRPPPQPGGHT------VGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPS--TGCGC 87
+P PPP P G G +P GG R PS C C
Sbjct: 16 SPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGG--------RCTQLPSREAACLC 67
Query: 88 PPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTG-GCCPASAQAGTGQTDVRTLCSLH 146
PPG + R ++ + G C G G C +S AGT + R
Sbjct: 68 PPGW-----------VGERCQLEDPCHSG---PCAGRGVCQSSVVAGTARFSCRCPRGFR 113
Query: 147 GVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASG-SCPDD---------CNDQGR 196
G C P G CS D S PP G SC D C G
Sbjct: 114 GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGT 173
Query: 197 CVRG----RCVCFPGYTGPSC---GWPSCPGDCQGRGRCVQGV-----CVCRAGFSGPDC 244
C+ RC C GYTGP C P P C+ G C Q C C GF G +C
Sbjct: 174 CLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNC 233
Query: 245 SQR--SCP-RGCSQRGRCEGG----RCVCDPGYTG-------DDCGMRSCPRGCSQRGRC 290
CP C G C G C C P +TG D+C ++ P C G C
Sbjct: 234 EVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ--PNACHNGGTC 291
Query: 291 ENG----RCVCNPGYTGE-------DCGVRSCPRGCSQRGRCKDGRCVCDPGYTG----- 334
N CVC G+TGE DC C G + R C C G TG
Sbjct: 292 FNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHL 351
Query: 335 -EDCGTRSCPWDCGEGGRCVDGR--CVCWPGYTG-------EDCSTRTCPRDCRGRGRCE 384
+ C + C D V+GR C C PG+TG ++CS P C GRC
Sbjct: 352 DDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANP--CEHLGRCV 409
Query: 385 DGE----CICDTGYSGDDC--GVRSC-PGDCNQRGRCEDG----RCVCWPGYTGT----- 428
+ + C C GY+G C V C G C + C D C+C G+TGT
Sbjct: 410 NTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVD 469
Query: 429 --DCGSRACPRDCRGRGRCENGVCVCNAGYSGEDC--GVRSCPGD-CRGRGRC----ESG 479
+C S C + R C C +G+SG C V C CR +C +
Sbjct: 470 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGY 529
Query: 480 RCMCWPGYTGRDCGTRA--CPGDCRGRGRCVDG----RCVCNPGFTGEDCGSR--RCPGD 531
C C G+ G C C D GRCVDG C C PG+TG C S+ C
Sbjct: 530 ECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 589
Query: 532 -CRGHGLCEDGV----CVCDAGYSGEDCSTR--SCPGGCRGRGQCLDG----RCVCEDGY 580
CR G C D V C C +G +G +C C G C DG CVC+ G+
Sbjct: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 649
Query: 581 SGEDCGVR--QCPND-CSQHGVCQDGV----CICWEGYVSEDC--SIRTCPSNCHGRGRC 631
+G C V +C + C + G C DG C+C G + C C G C
Sbjct: 650 TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
Query: 632 EEG----RCLCDPGYTGPTCATRM--------------------------CPADCRGR-- 659
+ RC+C+PG++GP C+ + CP +GR
Sbjct: 710 YDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC 769
Query: 660 --------------GRCVQG-----VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR- 699
GRC VC C G+ G C Q++ A P CGP +C
Sbjct: 770 ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC-QQDVDECAGPAPCGPHGICTN 828
Query: 700 -AG--QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDG----SCVCKDGYAGEDCGEEV 749
AG C C G+ GP C I C P C G C DG SC C G+AG C +V
Sbjct: 829 LAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV 888
Score = 236 bits (603), Expect = 3e-61
Identities = 213/737 (28%), Positives = 258/737 (35%), Gaps = 176/737 (23%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW 215
C CEPGW GP CS + S P A G+C D + C C PG G C
Sbjct: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD------GMGFHCTCPPGVQGRQCEL 771
Query: 216 --PSCPGDCQGRGRCVQG-----VCVCRAGFSGPDCSQR----SCPRGCSQRGRCE---- 260
P P C+ GRC VC C G+ GP C Q + P C G C
Sbjct: 772 LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAG 831
Query: 261 GGRCVCDPGYTGDDC--GMRSC-PRGCSQRGRCENG----RCVCNPGYTGEDCG--VRSC 311
C C GYTG C + C P C G C++G C C PG+ G C V C
Sbjct: 832 SFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC 891
Query: 312 PRGCSQRGRCKDG----RCVCDPGYTGEDC--GTRSC-PWDCGEGGRCVDG----RCVCW 360
G C D C C PGY G C C P C GG CVDG C+C
Sbjct: 892 LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCR 951
Query: 361 PGYTGEDCSTRTCP---RDCRGRGRCEDG----ECICDTGYSGDDCG--VRSCPGD-CNQ 410
PGYTG C P R C G C C C ++G C V C C
Sbjct: 952 PGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQN 1011
Query: 411 RGRC--EDGRCVCWPGYTGTDCGSRACP-------------RDCRGRGRC----ENGVCV 451
GRC C+C PG++G C R+ P + C+ G+C + CV
Sbjct: 1012 GGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV 1071
Query: 452 CNAGYSGEDCGVRSCP---GDCRGRGRCE----SGRCMCWPGYTGRDCG---TRACPGDC 501
C G +G C P C+ G C C C PGY G +C C
Sbjct: 1072 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC 1131
Query: 502 RGRGRCVD----GRCVCNPGFTG-------EDCGSRRCPGD-------CRGHGLCEDGV- 542
+ G C+D C C PG G +DCG PG C +G C D V
Sbjct: 1132 QHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCG----PGPPLDSGPRCLHNGTCVDLVG 1187
Query: 543 ---CVCDAGYSGEDCST--RSC-PGGCRG--RGQCLDG-----RCVCEDGYSGEDCGVRQ 589
C C GY+G C C G C CL RC+C G+SG C
Sbjct: 1188 GFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVL 1247
Query: 590 CP---NDCSQHGVCQDG---------VCICWEGY-------VSEDCSIRTCPSNCHGRGR 630
P C G C+ C C + + V+ C CP +
Sbjct: 1248 SPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQT 1307
Query: 631 CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPG 690
RC C PG +GP+C + C CL +G G
Sbjct: 1308 PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCL----HG---------------G 1348
Query: 691 GCGPRELCRAGQCVCVEGFRGPDC------------------AIQTCPGDCRGRGECHDG 732
C P L +C C +G+ GP C A Q GD R EC+
Sbjct: 1349 SCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSP 1408
Query: 733 SCVCKDGYAGEDCGEEV 749
C G+ G DC V
Sbjct: 1409 GC----GWDGGDCSLSV 1421
Score = 196 bits (499), Expect = 3e-49
Identities = 207/742 (27%), Positives = 252/742 (33%), Gaps = 175/742 (23%)
Query: 85 CGCPPGTEPPVLASEVQALRVRLE-----ILEELVKGLKEQCTGGCCPASAQAGTGQTDV 139
C CP G + P +V I L C GG S D
Sbjct: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 140 RTLCSLHGVFD-LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCV 198
+ D + +CSC PG+ GP C+ D + S P G+C D
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECL---SNPCGPGTCTD------HVA 906
Query: 199 RGRCVCFPGYTGPSC--GWPSC-PGDCQGRGRCVQGV----CVCRAGFSGPDCSQRSCP- 250
C C PGY G C P C P C G CV GV C+CR G++G C + P
Sbjct: 907 SFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC 966
Query: 251 --RGCSQRGRCE----GGRCVCDPGYTGDDCG--MRSCPR-GCSQRGRC--ENGRCVCNP 299
R C G C G RC C +TG C + C R C GRC C+C P
Sbjct: 967 LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPP 1026
Query: 300 GYTGEDCGVRSCP-------------RGCSQRGRCKD----GRCVCDPGYTGEDCGTRSC 342
G++G C +RS P + C G+C D CVC G TG C
Sbjct: 1027 GWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVD 1086
Query: 343 P---WDCGEGGRC---VDG-RCVCWPGYTGEDCS---TRTCPRDCRGRGRCED----GEC 388
P C GG C + G C C PGY G++C + C+ G C D C
Sbjct: 1087 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLC 1146
Query: 389 ICDTGYSG-------DDCGVRSCPGD-------CNQRGRCED----GRCVCWPGYTG--- 427
C G G DDCG PG C G C D RC C PGYTG
Sbjct: 1147 SCPPGTLGVLCEINEDDCG----PGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRC 1202
Query: 428 ----TDCGSRAC----PRDCRGRGRCENGVCVCNAGYSGEDCGVRSCP---------GDC 470
+C S AC RDC + C+C+AG+SG C P G C
Sbjct: 1203 EADINECRSGACHAAHTRDCL-QDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQC 1261
Query: 471 R---GRGRCESGRCMCWPGYTG-------RDCGTRACPGDCRGRGRCVDGRCVCNPGFTG 520
R G G + C C + G R C CP + RC C PG +G
Sbjct: 1262 RPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSG 1321
Query: 521 EDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC--PGGCRGRGQCLDGRCVCED 578
C R PG G S C+ C G CR RC C
Sbjct: 1322 PSC--RSFPGS--------------PPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365
Query: 579 GYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRG--------- 629
G++G C + S+ C C G + C C G
Sbjct: 1366 GWTGPRCEAPAAAPEVSEEPRCPRAACQAKRG--DQRCDRECNSPGCGWDGGDCSLSVGD 1423
Query: 630 ---RCEEGRC-------LCDPGYTGPTC-----------ATRMCP-------ADCRGRGR 661
+CE +C CDP + P C R C AD GR
Sbjct: 1424 PWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGR 1483
Query: 662 CVQGVCLCHVGYGGEDCGQEEP 683
C QG G+ G DC E P
Sbjct: 1484 CDQGCNTEECGWDGLDCASEVP 1505
Score = 76.3 bits (186), Expect = 6e-13
Identities = 57/203 (28%), Positives = 75/203 (36%), Gaps = 47/203 (23%)
Query: 594 CSQHGVC-----QDGVCICWEGYVSEDCSIRT-CPSN-CHGRGRCEEG--------RCLC 638
C+ G C ++ C+C G+V E C + C S C GRG C+ C C
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 639 DPGYTGPTCATR--MCPADCRGRGRCVQG-----VCLCHVGYGGEDCGQEEPPASACPGG 691
G+ GP C+ + C RC G +C C GY G C +
Sbjct: 109 PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDE------- 161
Query: 692 CGPRELCRAG----------QCVCVEGFRGPDC---AIQTCPGDCRGRGECHDGS----- 733
C E CR G +C C G+ GP C A+ P CR G C
Sbjct: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYD 221
Query: 734 CVCKDGYAGEDCGEEVPTIEGMR 756
C C G+ G++C V G R
Sbjct: 222 CACLPGFEGQNCEVNVDDCPGHR 244
Score = 44.7 bits (104), Expect = 0.002
Identities = 61/268 (22%), Positives = 71/268 (26%), Gaps = 81/268 (30%)
Query: 80 PPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDV 139
P C CPPG P S G + C A+ G
Sbjct: 1308 PRGPRCACPPGLSGPSCRS---------------FPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 140 RTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVR 199
L C+C GW GP C P A P +C DQ RC R
Sbjct: 1353 APLAPFF--------RCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQ-RCDR 1403
Query: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRC 259
C P CGW G C G C C R +
Sbjct: 1404 -EC------NSPGCGWDG-------------GDCSLSVGDPWRQCEALQCWRLFNNSR-- 1441
Query: 260 EGGRCVCDPGYTGDDC--GMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQ 317
CDP + C C G +R CNP Y + C+
Sbjct: 1442 ------CDPACSSPACLYDNFDCHAGGRER--------TCNPVY----------EKYCAD 1477
Query: 318 RGRCKDGRCVCDPGYTGEDCGTRSCPWD 345
DGRC + C T C WD
Sbjct: 1478 --HFADGRC-------DQGCNTEECGWD 1496
Score = 39.3 bits (90), Expect = 0.084
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 14/94 (14%)
Query: 679 GQEEPPA---SACPGGCGPREL-CRAGQCVCVEGFRGPDCAIQT-C-PGDCRGRGECHDG 732
G PP S C G +L R C+C G+ G C ++ C G C GRG C
Sbjct: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSS 96
Query: 733 --------SCVCKDGYAGEDCGEEVPTIEGMRMH 758
SC C G+ G DC P + H
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAH 130
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 265 bits (678), Expect = 6e-70
Identities = 365/1749 (20%), Positives = 649/1749 (37%), Gaps = 220/1749 (12%)
Query: 2307 EELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRV-PGHEDRVTISGLEPDN 2365
++L+ ++ T +W+ + + YK G + T V P V +S L+P+
Sbjct: 636 KDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPET 695
Query: 2366 KYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPD 2425
Y +N+ + + A EET TE AP L VT + D
Sbjct: 696 LYLVNVTAEYE-------DGFSIPLAGEET---TEEVKGAPR--------NLKVTDETTD 737
Query: 2426 SLSLSWTVPQGRFDSFTVQYKD-RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHE 2484
S ++WT GR + + Y+ G + V + T+ L P KY++ + +
Sbjct: 738 SFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYF 797
Query: 2485 GRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTV 2544
GP + + A E+V P +L V+ + ++ LSW+
Sbjct: 798 S---GPGTPLTGNAATEEVRGNPR------------------DLRVSDPTTSTMKLSWSG 836
Query: 2545 PQGRFDSFTVQYKD-RDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVS 2603
G+ + V Y G Q V V G + ++GL+ G +Y + + L+ +
Sbjct: 837 APGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALF 896
Query: 2604 AVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYR 2663
G T +E + Q +L D T S+ WT G + V ++
Sbjct: 897 GEGTTLEERGSPQ----------------DLVTKDITDTSIGAYWTSAPGMVRGYRVSWK 940
Query: 2664 N--GDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETP 2721
+ D +P I L+P+ KY+++++ + P++
Sbjct: 941 SLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT----------GD 990
Query: 2722 SPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRD-GRPQVM 2780
+ TELS ++ L V + +++ ++W G ++ V Y+ G+ V
Sbjct: 991 ATTELSQDSKT---------LKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVA 1041
Query: 2781 RVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPP 2840
+V + + L+P Y + V P+ +G E + Q TT
Sbjct: 1042 KVPPTVTSTVLKRLQPQTTYDI---------TVLPIYKMG----EGKLRQGSGTTASRFK 1088
Query: 2841 NKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYR-NGDGQPKVVRVPG-HEDGVTIS 2898
+ PR L +D T S ++W G+ + V + GD + V G +++ V +
Sbjct: 1089 S-PR--NLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
Query: 2899 GLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTV 2958
L YK+N++G G P+ +T + T P S G +
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSS------------GMECL 1193
Query: 2959 TGSSPDSLSL---SWTIPQGRFD------SFTVQYKD-RDGRPQVVRVRGEESEVTVGGL 3008
T + D + L SW+I + F S V+ D R Q+ + T L
Sbjct: 1194 TRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQL 1253
Query: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068
K L + G + G+ + + M P ++G L
Sbjct: 1254 NAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR---KIGVLITDG 1310
Query: 3069 ATPDSLSL-SWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLY 3127
+ D + S + + + F + +N D E + + +PD + N+
Sbjct: 1311 KSQDDVEAPSKKLKDEGVELFAIGIKNAD-----------EVELKMIATDPDDTHAYNVA 1359
Query: 3128 GFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVP 3187
F R+ I + S + P E P L ++ + S +SWT P
Sbjct: 1360 DFESLSRIVDDLTINLCN---------SVKGPGDLEAP--SNLVISERTHRSFRVSWTPP 1408
Query: 3188 QGRFDSFTVQYKD-RDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVST 3246
D + V+Y G+ Q V E+ + L+P +Y +++Y + E + P+
Sbjct: 1409 SDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKG 1468
Query: 3247 VGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQG----QPQ 3302
T P+P L + V ++ + W G +++ Y+ + +P+
Sbjct: 1469 TEKTLPVPVV--------SLNIYDVGPTTMHVQWQPVGGA-TGYILSYKPVKDTEPTRPK 1519
Query: 3303 AVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVT 3362
V + + + ++ L P +Y + + + PV V T P PR +L +
Sbjct: 1520 EVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLP----LPRPQDLKLR 1575
Query: 3363 DATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLY 3422
D T ++ + W G+ ++V+YK + ++ V V ++ +++ L Y +
Sbjct: 1576 DVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVS 1635
Query: 3423 GLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYR 3482
+ P++A TT P+ P L + E TS R +W + + +
Sbjct: 1636 AVHDEGESPPVTAQETTRPV-----PAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690
Query: 3483 DTDGQPRAVPVA-ADQRTVTVEDLEPGKKYKFLLYGLLGGK-RLGPVSALGMTAPEEDTP 3540
+ + D+ T+ E+L P Y+ + + + + T P T
Sbjct: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750
Query: 3541 APELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQ--PQAL 3598
AP+ P L V + T +S+ + W A G + + Y+ + G+ Q
Sbjct: 1751 APKSGPRN-----------LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
Query: 3599 LVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQ 3658
+ G Q+ +++ L+P TPY + L+ G ++ G T + +
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKT----------KPLNTVRN 1849
Query: 3659 LSVTDVTTSSLRLNWEAPPGAFDSFLLRF--GVPSPSTLEPHPRPLLQRELMVPGTRHSA 3716
L V D +TS+L + W+ G + L + P L P +PG + A
Sbjct: 1850 LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVP-----------IPGNTNYA 1898
Query: 3717 VLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMP 3776
+LR+L+ T Y++T+ + T RTL L R++Q S V W P
Sbjct: 1899 ILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGL--ARNVQVYNPTPNSLDVRWDP 1956
Query: 3777 PPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL 3835
P ++V Y DG P +S+ V G R L+ LIP Y V +V++ E P
Sbjct: 1957 APGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS 2016
Query: 3836 TGFLTTVP-DGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAET--PGS 3892
T+P GP LR T + W PV Y + + P+ T PG
Sbjct: 2017 PAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGR 2076
Query: 3893 AVDYPLHDLVLHTNYTATVRGL----RGPNLTSPASITFTTGLEAPRDLEAKEVTPRTAL 3948
+ L L T Y TV + G +LT T GL P+++ +
Sbjct: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGR---TVGLLPPQNIHISDEWYTRFR 2133
Query: 3949 LTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLL 4008
++W P GY + + G G +TS+ L L PST+Y+ + A + L
Sbjct: 2134 VSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLS 2193
Query: 4009 PPVSTSFTT 4017
P++ TT
Sbjct: 2194 VPLTDQGTT 2202
Score = 244 bits (624), Expect = 1e-63
Identities = 400/1990 (20%), Positives = 713/1990 (35%), Gaps = 352/1990 (17%)
Query: 843 PQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYV-SAGNQRVRLEVPPEADGTLLTDLMPG 901
P+DL VT + W V + ++Y +AG+ V + P + +L+ L P
Sbjct: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPE 694
Query: 902 VEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQ 961
Y+V VTAE S P + G TT+ + P+
Sbjct: 695 TLYLVNVTAEYEDGFSIPLA----------------------GEETTEEVKGA-----PR 727
Query: 962 ELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPP 1021
L + + T ++ WT P +++ R G + E P + R+ +
Sbjct: 728 NLK----VTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLI 783
Query: 1022 PGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLR 1081
P T YE+S+ G P P+ ++ G PR +L V+D T+ ++ L
Sbjct: 784 PDTKYEVSVIPEYFSG-PGTPLTGNAATEEVR-------GNPR--DLRVSDPTTSTMKLS 833
Query: 1082 WTVPEGEFDSFVIQYKD-RDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHG 1140
W+ G+ +++ Y G+ Q V V G + V+ L G +Y +
Sbjct: 834 WSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGD 893
Query: 1141 PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQ----YRDR 1196
L E L + G+P L +TD S+ WT G + V Y D
Sbjct: 894 ALFGEGTTLEER----GSPQDLVTKDITDT---SIGAYWTSAPGMVRGYRVSWKSLYDDV 946
Query: 1197 DGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRP 1256
D + +P + ++ +L P+ KYR ++F + PLT D TT + +
Sbjct: 947 DTGEKNLPEDAIHT--MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKT--- 1001
Query: 1257 EFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKD-AQGQPQAVPVAGDENEVT 1315
L V T +++R++W A G ++ V Y+ +G+ V
Sbjct: 1002 ----------LKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
Query: 1316 VPGLDPDRKYKMNLYGL----RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPE 1371
+ L P Y + + + G+ R G + ++ SP L T
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFK---------SPRNLKTS------ 1096
Query: 1372 EPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDR--DGRPRAVRVGGKESEVTVGG 1429
+P + VT W G + V + D R + VG ++ V +
Sbjct: 1097 DPTMSSFRVT----------WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEE 1146
Query: 1430 LEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNS 1489
L G YK++++G+ +G P+ +T P S +E +T +
Sbjct: 1147 LRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGME------CLTRAEADI 1200
Query: 1490 VGL---SWTVPEGQF---DSFIVQYKDK-DGQPQVVPVAADQREVTVYNLEPERKYKMNM 1542
V L SW++ F SFI + + D P+ V +A Q Y+ +P ++++N
Sbjct: 1201 VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ-----YSGDPRTEWQLNA 1255
Query: 1543 YGLHDGQRMGPLSVVIVTAPLPPAPA-----------------TEASKPPLEPRLGELTV 1585
+ S++ A LP T+A P ++G L
Sbjct: 1256 H-------RDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLIT 1308
Query: 1586 TDITPDSV-GLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFL 1644
+ D V S + + + F + K+ AD+ E+ + +P + +
Sbjct: 1309 DGKSQDDVEAPSKKLKDEGVELFAIGIKN-----------ADEVELKMIATDPDDTHAYN 1357
Query: 1645 LFGIQDGKR-RSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDS 1703
+ + R +++ +G AP L +++ T S R+SWT P D
Sbjct: 1358 VADFESLSRIVDDLTINLCNSVKGPGDLEAP---SNLVISERTHRSFRVSWTPPSDSVDR 1414
Query: 1704 FVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEA 1761
+ V++ G Q V E S + L +Y +Y ++ + PL GT
Sbjct: 1415 YKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPL--KGT--- 1469
Query: 1762 RSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYK----DRDGQP 1817
K P P + L + V ++ + W P G +++ YK +P
Sbjct: 1470 --------EKTLPVPVV--SLNIYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRP 1518
Query: 1818 QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTP 1877
+ V + ++ ++ + L P Y + + + H P++ +T
Sbjct: 1519 KEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL-------------- 1564
Query: 1878 PAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLS 1937
P P P +L + + T T+++ W G+ + ++Y + ++ V + +L
Sbjct: 1565 PLPRPQ--DLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK 1622
Query: 1938 GLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTD 1997
L S Y V++ D PV T E +P PT L +T+
Sbjct: 1623 DLFSQTLYTVSVSAVHDEGESPPV-----TAQETTRPVPAPT------------NLKITE 1665
Query: 1998 ATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056
T + +W + + + G + G E + L P+ Y+
Sbjct: 1666 VTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYE---- 1721
Query: 2057 GFHGGQRMGPVSVVGVTAAEEET-----PSPTEPSMEAPEPAEEPLLGELTVTGSSPDSL 2111
VS+ + E E+ T P + P P L V ++ +SL
Sbjct: 1722 ----------VSITAIYPDESESDDLIGSERTLPILTTQAPKSGP--RNLQVYNATSNSL 1769
Query: 2112 SLSWTVPQGRFDSFTVQYKDR--DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEG 2169
++ W GR + + Y+ +G Q +GG ++ V + L+P Y + + L+
Sbjct: 1770 TVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPD 1829
Query: 2170 RRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFK 2229
G ++ G T PL +R + V D ++ +L++ W EG + + +
Sbjct: 1830 GEGGRMTGRGKT--------KPLNTVR--NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYA 1879
Query: 2230 NGDGQP-KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEM 2288
G P + V +PG+ + + L+PD Y + + + G S G T
Sbjct: 1880 PAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTL------- 1932
Query: 2289 APASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDG--QPKA 2346
++ + V + TP+SL + W G + V Y DG ++
Sbjct: 1933 -------------MRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSES 1979
Query: 2347 TRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAP 2406
VPG+ V + L PD Y +NL + + + E PSP +
Sbjct: 1980 IVVPGNTRMVHLERLIPDTLYSVNL--------------VALYSDGEGNPSPAQGRTLPR 2025
Query: 2407 EPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRP--QVVRVGGEESEV 2464
P L V G + +SLS++W G + + Y G P + V G + V
Sbjct: 2026 SGPR-----NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV 2080
Query: 2465 TVGGLEPGRKYKMHLYGLHE----GRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
+ L+P YK+ + ++E G G TVG+ PQ
Sbjct: 2081 ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQ-------------------- 2120
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGL 2580
+ ++ +SW + + YK G+ + T+ L
Sbjct: 2121 ------NIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNL 2174
Query: 2581 EPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDAT 2640
P Y +++Y ++ P++ G T + + +L
Sbjct: 2175 NPSTTYDVNVYAQYDSGLSVPLTDQGTT------------------LYLNVTDLKTYQIG 2216
Query: 2641 PDSLSLSWTVPEGQFDHFLVQYRNGDG-QPKAVRVPGHEDGVTISGLEPDHKYKMNLYGF 2699
D+ + W+ P + ++ DG + + + V G E +GL PD Y + ++
Sbjct: 2217 WDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF-V 2274
Query: 2700 HGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLL--GELTVTGSSPDSLSL--- 2754
GP GV+ E T PTE TE P PP P + G+ D + L
Sbjct: 2275 QTPNLEGP----GVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDA 2330
Query: 2755 SWTIPQGHFD 2764
SW+I +F+
Sbjct: 2331 SWSIGDDNFN 2340
Score = 240 bits (613), Expect = 2e-62
Identities = 385/1880 (20%), Positives = 681/1880 (36%), Gaps = 292/1880 (15%)
Query: 1992 ELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRV-PGHEEGVTISGLEPDHK 2050
+L+ ++ T +W+ + + Y+ G + V P V +S L+P+
Sbjct: 637 DLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETL 696
Query: 2051 YKMNLYG-FHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPD 2109
Y +N+ + G + A EET TE AP L VT + D
Sbjct: 697 YLVNVTAEYEDG--------FSIPLAGEET---TEEVKGAPR--------NLKVTDETTD 737
Query: 2110 SLSLSWTVPQGRFDSFTVQYKD-RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHE 2168
S ++WT GR + + Y+ G + V + T+ L P KY++ + +
Sbjct: 738 SFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYF 797
Query: 2169 GRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQF 2228
GP + + A EE P + V D T+ ++ LSW+ G+ +LV +
Sbjct: 798 S---GPGTPLTGNAATEEVRGNPR------DLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
Query: 2229 KN-GDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEE 2287
G+ + V V G + GL+ +Y +++ + + G T +E
Sbjct: 849 TPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL---EER 905
Query: 2288 MAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKN--GDGQPK 2345
+P ++L D T S+ WT G + V +K+ D
Sbjct: 906 GSP----------------QDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTG 949
Query: 2346 ATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEA 2405
+P I L+P+ KY+++++ + P++ T +++ +
Sbjct: 950 EKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKT-------- 1001
Query: 2406 PEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRD-GRPQVVRVGGEESEV 2464
L V + +++ ++W G+ ++ V Y+ G+ V +V +
Sbjct: 1002 -----------LKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTST 1050
Query: 2465 TVGGLEPGRKYK---MHLYGLHEGR-RVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
+ L+P Y + +Y + EG+ R G G TA + SP T P
Sbjct: 1051 VLKRLQPQTTYDITVLPIYKMGEGKLRQGS----GTTASR-----FKSPRNLKTSDP--- 1098
Query: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR--DGRPQAVRVGGQESKVTVR 2578
+ S ++W G + V + D R + VG ++ V +
Sbjct: 1099 -------------TMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
Query: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
L G YK++++G+ +G P+ VG T +P ++ G +T
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPL--VGQEMTTLSDTTVMPILSS--------GMECLTR 1195
Query: 2639 ATPDSLSL---SWTVPEGQFD---HFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHK 2691
A D + L SW++ F F+ + D PK V++ + SG +P +
Sbjct: 1196 AEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ----YSG-DPRTE 1250
Query: 2692 YKMNLYGFHGG--QRVGPISVIG---VTAAEEETPSPTELSTEAPEPPEEPLLGELTVTG 2746
+++N + Q V + G +T T+A P +G L G
Sbjct: 1251 WQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDG 1310
Query: 2747 SSPDSLSL-SWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLY 2805
S D + S + + F + K+ D E E+ + +P + ++
Sbjct: 1311 KSQDDVEAPSKKLKDEGVELFAIGIKNAD-----------EVELKMIATDPDDTHAYNVA 1359
Query: 2806 GLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVP 2865
R+ T+ + P P N L +++ T S +SW P
Sbjct: 1360 DFESLSRIVDDLTINLCNSVKG-----PGDLEAPSN------LVISERTHRSFRVSWTPP 1408
Query: 2866 EGQFDHFLVQYRN-GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISV 2924
D + V+Y G+ + V E + L+P+ +Y +N+Y + P+
Sbjct: 1409 SDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLK- 1467
Query: 2925 IGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQY 2984
E+ P P L + P ++ + W P G + + Y
Sbjct: 1468 ----GTEKTLPVPVV---------------SLNIYDVGPTTMHVQWQ-PVGGATGYILSY 1507
Query: 2985 KD----RDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKD 3040
K RP+ VR+ +++ + L P +Y + + + PV+ VT P
Sbjct: 1508 KPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPL- 1566
Query: 3041 EAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPK 3100
PR +L + D T ++++ W G+ ++V+Y+ + K
Sbjct: 1567 ------------------PRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVK 1608
Query: 3101 AVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPE 3160
V V E ++ L Y +++ H PV+A E P P + + E
Sbjct: 1609 EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTA---QETTRPVPAPTNLKITE 1665
Query: 3161 APEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVG 3220
E G S ++W P G D + G+E+ +
Sbjct: 1666 VTSEGFRGTWDHGASDVSLYRITW-APFGSSDKME------------TILNGDENTLVFE 1712
Query: 3221 GLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLG--ELAVAAVTSDSVGL 3278
L P Y++ + ++ + +G LP P+ G L V TS+S+ +
Sbjct: 1713 NLNPNTIYEVSITAIYPDESESD-DLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTV 1771
Query: 3279 SWTVAQGPFDSFLVQYRDA--QGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKR 3336
W A G + + Y+ + +G Q + G +V + L P Y + L
Sbjct: 1772 KWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 3337 HGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKD-KDGRLQ 3395
G + + TKP + L V D + ++ + W EG + + Y G +
Sbjct: 1832 GGRMTGRGK----TKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEE 1887
Query: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455
+VP+ N ++ L+P Y + + G S T L + L + + V
Sbjct: 1888 LVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTS--DTGRTLMRGLARN---VQV 1942
Query: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDG--QPRAVPVAADQRTVTVEDLEPGKKYKF 3513
T +SL + W A GP + V Y DG ++ V + R V +E L P Y
Sbjct: 1943 YNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSV 2002
Query: 3514 LLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLS 3573
L L P A G T P PR L V T +S+ ++
Sbjct: 2003 NLVALYSDGEGNPSPAQGRTLPRSG----------------PR--NLRVFGETTNSLSVA 2044
Query: 3574 WSVAQGPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 3631
W A GP + + Y T G P + V G ++ +++ L+P TPY+ + ++E
Sbjct: 2045 WDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDG 2104
Query: 3632 GPLSAEG-TTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVP 3690
G L+ G T GL P + ++D + R++W+ P + + +
Sbjct: 2105 GHLTGNGRTVGLLPP-----------QNIHISDEWYTRFRVSWDPSPSPVLGYKIVY--- 2150
Query: 3691 SPSTLEPHPRPLLQRELM--VPGTRHSAVLRDLRSGTLYSLTLY-----GLRGPHKADSI 3743
+P+ E M G S L +L T Y + +Y GL P +
Sbjct: 2151 ---------KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPL---TD 2198
Query: 3744 QGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDG 3803
QGT L+ DL+ +I + V W P + A S+++ ADG Q + V G
Sbjct: 2199 QGTTLYLNVT-----DLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG 2252
Query: 3804 QARTQKLQGLIPGARYEVTV 3823
+ GL P Y VTV
Sbjct: 2253 SETSHCFTGLSPDTDYGVTV 2272
Score = 240 bits (612), Expect = 2e-62
Identities = 397/1875 (21%), Positives = 681/1875 (36%), Gaps = 301/1875 (16%)
Query: 737 KDGY----AGEDCGEEVPTIEGMRMHLLEETT--VRTEWTPAPGPVDAYEIQFIPTTEGA 790
+DG+ AGE+ EEV + + +ETT + WT APG V Y I + P G
Sbjct: 706 EDGFSIPLAGEETTEEVKGAP-RNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGE 764
Query: 791 SPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITT--MIDGPQDLRV 848
S T P + L P +Y+V+V + G P + T + P+DLRV
Sbjct: 765 SREVTT--PPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRV 822
Query: 849 VAVTPTTLELGWLRPQAEVDRFVVSYVS-AGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
T +T++L W +V +++V+Y AG + + V + T+L L G +Y ++
Sbjct: 823 SDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALS 882
Query: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
VTA + A+ L GTT E S PQ+L
Sbjct: 883 VTA-----------LYASGAGDALFGEGTTLEERGS----------------PQDL---- 911
Query: 968 VLGRDETG-RLRVVWTAQPDTFAYFQLRMR-VPEGPGAHEEVLPGDVRQALVPPPPPGTP 1025
+ +D T + WT+ P +++ + + + E+ LP D ++ P T
Sbjct: 912 -VTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970
Query: 1026 YELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVP 1085
Y +S+ G+ +P+ + ++ L V + T +++ + W
Sbjct: 971 YRISVFATYSSGE-GEPLTGDATTELSQDSK----------TLKVDEETENTMRVTWKPA 1019
Query: 1086 EGEFDSFVIQYKDRD-GQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
G+ ++ + Y+ G+ V V S V+ L P Y + +
Sbjct: 1020 PGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIY-------KMG 1072
Query: 1145 EAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDR-DGRPQVV 1203
E K+ S + NL +DPT S ++W G+ + V + D R
Sbjct: 1073 EGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGE 1132
Query: 1204 PVEGP-ERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTA-DGTTAPERKEEPPRPEFLEQ 1261
V GP + + V+ L Y+ +FG+ + PL + TT + P +E
Sbjct: 1133 LVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMEC 1192
Query: 1262 PLLGELTVTGVTPDSLRLSWTVAQGPF---DSFMVQYKDA-QGQPQAVPVA-----GDEN 1312
E + + SW++ + F SF+ + + P+ V +A GD
Sbjct: 1193 LTRAEADIVLLVDG----SWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPR 1248
Query: 1313 EVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEE 1372
T L+ R K L + G ++ T+A P
Sbjct: 1249 --TEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMAL------NFIRQQNFRTQAGMRPRA 1300
Query: 1373 PLLGELTVTGSSPDSLSL-FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLE 1431
+G L G S D + + + F + K+ D E E+ + +
Sbjct: 1301 RKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNAD-----------EVELKMIATD 1349
Query: 1432 PGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVG 1491
P + ++ R+ V + + + P E+P L +++ T S
Sbjct: 1350 PDDTHAYNVADFESLSRI--VDDLTINLCNSVKGPGDLEAP-----SNLVISERTHRSFR 1402
Query: 1492 LSWTVPEGQFDSFIVQYKD-KDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQR 1550
+SWT P D + V+Y G+ Q V+ + + +L+PE +Y +N+Y + + +
Sbjct: 1403 VSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEY 1462
Query: 1551 MGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQ 1610
PL T P+P + L + D+ P ++ + W P G +++
Sbjct: 1463 SEPLKGTEKTLPVP---------------VVSLNIYDVGPTTMHVQWQ-PVGGATGYILS 1506
Query: 1611 YK----DRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVAR 1666
YK +P+ V + ++ + DL P+ +Y + + PV+V T+
Sbjct: 1507 YKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPL 1566
Query: 1667 GDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFK-DKDGPQVVPVEGHERS 1725
PR +L + D T ++ + W G+ ++V++K ++ + V V+ E S
Sbjct: 1567 --------PRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETS 1618
Query: 1726 VTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRP-PKPRLGEELQV 1784
++ L + Y + + + P+TA TT RP P P L++
Sbjct: 1619 TSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT------------RPVPAP---TNLKI 1663
Query: 1785 TTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPV-EGSLREVSVPGLDPAHRYKLL 1843
T VT +W + + + ++ + G + L+P Y+
Sbjct: 1664 TEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYE-- 1721
Query: 1844 LYGLHHGKRVGPISAVAITAGREETE----TETTAP--TPPAPEPHLGELTVEEATSHTL 1897
+S AI E++ +E T P T AP+ L V ATS++L
Sbjct: 1722 ------------VSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSL 1769
Query: 1898 HLSWMVTEGEFDSFEIQY--TDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDG 1955
+ W G + I Y + +G Q IGG +N + L L+ D Y +T+
Sbjct: 1770 TVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPD 1829
Query: 1956 KHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFD 2015
G + T P + L V D + +L++ W EG
Sbjct: 1830 GEGGRMTGRGKTKPLN-----------------TVRNLRVYDPSTSTLNVRWDHAEGNPR 1872
Query: 2016 HFLVQYRNGDGQP-KAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTA 2074
+ + Y G P + V +PG+ + L+PD Y + + + G S G T
Sbjct: 1873 QYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTL 1932
Query: 2075 AEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDG 2134
L + V +P+SL + W G + V Y DG
Sbjct: 1933 M-------------------RGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDG 1973
Query: 2135 -RP-QVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPL 2192
RP + + V G V + L P Y ++L L+ P A G T P
Sbjct: 1974 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP--------- 2024
Query: 2193 AKLRLGQMTVRDI--TSDSLSLSWTVPEGQFDHFLVQFKNGDGQP--KAVRVPGHEDGVT 2248
R G +R T++SLS++W +G + + + G P + VPG + V
Sbjct: 2025 ---RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
Query: 2249 ISGLEPDHKYKMNLYGFH----GGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKP 2304
+ L+PD YK+ + + GG G VGL P
Sbjct: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPP---------------------- 2119
Query: 2305 RLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKN-GDGQPKATRVPGHEDRVTISGLEP 2363
+ + ++D +SW + + YK G +P V G T+ L P
Sbjct: 2120 --QNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFV-GEMTSYTLHNLNP 2176
Query: 2364 DNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSS 2423
Y +N+Y + P++ G T T +L
Sbjct: 2177 STTYDVNVYAQYDSGLSVPLTDQGTTLYLNVT--------------------DLKTYQIG 2216
Query: 2424 PDSLSLSWTVPQGRFDSFTVQYKDRDG-RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGL 2482
D+ + W+ P S+ ++ DG R Q + V G E+ GL P Y + ++
Sbjct: 2217 WDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF-- 2273
Query: 2483 HEGRRVGPVSTVGVTAPQEDVDE--TPSPTEPGTEAPGPPEEPLL--GELTVTGSSPDSL 2538
V T + P V E T PTE TE P PP P + G+ D +
Sbjct: 2274 --------VQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIV 2325
Query: 2539 SL---SWTVPQGRFD 2550
L SW++ F+
Sbjct: 2326 FLTDASWSIGDDNFN 2340
Score = 231 bits (590), Expect = 9e-60
Identities = 410/1971 (20%), Positives = 712/1971 (36%), Gaps = 310/1971 (15%)
Query: 1058 KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVE-GPQRSAV 1116
K+ PP+ +L+ ++ TS W+ S+ I YK+ G +V VE S V
Sbjct: 630 KAYVPPK--DLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVV 687
Query: 1117 ITSLDPGRKYKFVLYGFVGKKRHG---PLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPD 1173
++SL P Y L + G PL E ++ G P NL VTD T D
Sbjct: 688 LSSLKPETLY---LVNVTAEYEDGFSIPLAGEET----TEEVKGAPR---NLKVTDETTD 737
Query: 1174 SLHLSWTVPEGQFDTFMVQYRD-RDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN 1232
S ++WT G+ + + YR G + V +R + +L PD KY ++
Sbjct: 738 SFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYF 797
Query: 1233 KKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFM 1292
PLT G A E PR +L V+ T +++LSW+ A G ++
Sbjct: 798 SGPGTPLT--GNAATEEVRGNPR----------DLRVSDPTTSTMKLSWSGAPGKVKQYL 845
Query: 1293 VQYKD-AQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQE 1351
V Y A G+ Q V V GD + GL +Y +++ L A A
Sbjct: 846 VTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTAL-----------YASGAGDA 894
Query: 1352 DVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD--R 1409
E + E G SP++ + ++T T S+ +WT G + V +K
Sbjct: 895 LFGEGTTLEERG-----SPQDLVTKDITDT-----SIGAYWTSAPGMVRGYRVSWKSLYD 944
Query: 1410 DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPAT 1469
D + + L+P KY++ ++ + P++ T Q+
Sbjct: 945 DVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSK---- 1000
Query: 1470 ESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKD-GQPQVVPVAADQREVT 1528
L V + T N++ ++W G+ ++ V Y+ G+ V V
Sbjct: 1001 ---------TLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
Query: 1529 VYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDI 1588
+ L+P+ Y + + ++ +MG L T AS+ PR L +D
Sbjct: 1052 LKRLQPQTTYDITVLPIY---KMG-------EGKLRQGSGTTASRFK-SPR--NLKTSDP 1098
Query: 1589 TPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAADQREVTIPDLEPSRKYKFLLF 1646
T S ++W GE + V + D + + V V + +L YK +F
Sbjct: 1099 TMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVF 1158
Query: 1647 GIQDGKRRSP-VSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRL---SWTVPEGQF- 1701
G+ DG SP V E T++ P G +T D + L SW++ F
Sbjct: 1159 GMFDGGESSPLVGQEMTTLSDTTVMPILSS--GMECLTRAEADIVLLVDGSWSIGRANFR 1216
Query: 1702 --DSFVVQFKD--KDGPQVVPVEGHERS---VTVTPLDAGRKYRFLLYGLLGKKRHGPLT 1754
SF+ + + GP+ V + + S T L+A R + LL + G T
Sbjct: 1217 TVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNT 1276
Query: 1755 ADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRD 1814
G + T+ +PR +G+ T + Q D K +D
Sbjct: 1277 LTGMALNFIRQQNFRTQAGMRPR-----------ARKIGVLITDGKSQDDVEAPSKKLKD 1325
Query: 1815 GQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLH----HGKRVGPISAVAITAGREETET 1870
EG E+ G+ A +L + H V +++ + T
Sbjct: 1326 --------EGV--ELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVD-DLTIN 1374
Query: 1871 ETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD-RDGQLQMVRIGG 1929
+ P L + E T + +SW D ++++Y G+ Q +
Sbjct: 1375 LCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSR 1434
Query: 1930 DRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPR 1989
L L+ + Y+V +Y E++ SEP T E +
Sbjct: 1435 METSTVLKDLKPETEYVVNVYSV-----------------VEDEYSEPLKGT-EKTLPVP 1476
Query: 1990 LGELTVTDATPDSLSLSWTVPEGQFDHFLVQYR----NGDGQPKAVRVPGHEEGVTISGL 2045
+ L + D P ++ + W P G +++ Y+ +PK VR+ + ++ L
Sbjct: 1477 VVSLNIYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDL 1535
Query: 2046 EPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTG 2105
P+ +Y + + PV+V VT + P P +L +
Sbjct: 1536 VPNTEYAVTVQAVLHDLTSEPVTVREVT-------------LPLPRPQ------DLKLRD 1576
Query: 2106 SSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYG 2165
+ ++++ W G+ + V+YK + + V V E+ ++ L Y + +
Sbjct: 1577 VTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSA 1636
Query: 2166 LHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFL 2225
+H+ PV+A T P AP + + ++TS+ +W +
Sbjct: 1637 VHDEGESPPVTAQETTRP----VPAPT------NLKITEVTSEGFRGTWDHGASDVSLYR 1686
Query: 2226 VQFKN-GDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGK 2284
+ + G + G E+ + L P+ Y++++ + P + G
Sbjct: 1687 ITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIY------PDESESDDLIGS 1740
Query: 2285 DEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYK--NGDG 2342
+ + +T+ P P L V +AT +SL++ W G+ + + Y+ G+G
Sbjct: 1741 ERTLPILTTQAPKSGP------RNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
Query: 2343 QPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPS 2402
+ T + G ++ V + L+PD Y + + + G ++ G T P T +
Sbjct: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKT-----KPLNTVRN 1849
Query: 2403 MEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRP-QVVRVGGEE 2461
+ +P S +L++ W +G + + Y G P ++V + G
Sbjct: 1850 LRVYDP--------------STSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNT 1895
Query: 2462 SEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPE 2521
+ + L+P Y + V PV T G D T
Sbjct: 1896 NYAILRNLQPDTSYTV---------TVVPVYTEGDGGRTSDTGRTLM------------- 1933
Query: 2522 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDG-RP-QAVRVGGQESKVTVRG 2579
L + V +P+SL + W G + V Y DG RP +++ V G V +
Sbjct: 1934 RGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLER 1993
Query: 2580 LEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDA 2639
L P Y ++L L+ P A G T +P P L +
Sbjct: 1994 LIPDTLYSVNLVALYSDGEGNPSPAQGRT---------LPRSGPR--------NLRVFGE 2036
Query: 2640 TPDSLSLSWTVPEGQFDHFLVQYRNGDGQP--KAVRVPGHEDGVTISGLEPDHKYKMNLY 2697
T +SLS++W +G + + Y G P + VPG + V + L+PD YK+ +
Sbjct: 2037 TTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVI 2096
Query: 2698 GFH----GGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLS 2753
+ GG G +G+ PP+ + + T
Sbjct: 2097 AVYEDGDGGHLTGNGRTVGLL------------------PPQNIHISDEWYT-----RFR 2133
Query: 2754 LSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2813
+SW + + YK + GE + T+ L P Y +++Y ++
Sbjct: 2134 VSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLS 2193
Query: 2814 GPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFL 2873
P++ G TT + T +L D+ + W P +
Sbjct: 2194 VPLTDQG-------TTLYLNVT-----------DLKTYQIGWDTFCVKWS-PHRAATSYR 2234
Query: 2874 VQYRNGDG-QPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEE 2932
++ DG + + + V G E +GL PD Y + ++ GP GV+ E
Sbjct: 2235 LKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF-VQTPNLEGP----GVSVKEH 2289
Query: 2933 ETPAPTEPSTEAPEPPEEPLL--GELTVTGSSPDSLSL---SWTIPQGRFD 2978
T PTE TE P PP P + G+ D + L SW+I F+
Sbjct: 2290 TTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN 2340
Score = 224 bits (570), Expect = 2e-57
Identities = 404/1986 (20%), Positives = 713/1986 (35%), Gaps = 341/1986 (17%)
Query: 1266 ELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVA-GDENEVTVPGLDPDRK 1324
+L+ + VT + +W+ A S+ + YK+A G + V V + L P+
Sbjct: 637 DLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETL 696
Query: 1325 YKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSS 1384
Y +N+ TA ED P E TE + L VT +
Sbjct: 697 YLVNV-----------------TAEYEDGFSIPLAGEETTEEVKGAPR----NLKVTDET 735
Query: 1385 PDSLSLFWTVPQGSFDSFTVQYKD-RDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGL 1443
DS + WT G + + Y+ G R V + T+ L P KY++ +
Sbjct: 736 TDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPE 795
Query: 1444 HEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDS 1503
+ GP + + A +E PR +L V+D T +++ LSW+ G+
Sbjct: 796 YFS---GPGTPLTGNAATEEVRG-------NPR--DLRVSDPTTSTMKLSWSGAPGKVKQ 843
Query: 1504 FIVQYKD-KDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAP 1562
++V Y G+ Q V V D + L+ +Y +++ L+ L T
Sbjct: 844 YLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLE 903
Query: 1563 LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYK----DRDGQP 1618
+P +L DIT S+G WT G + V +K D D
Sbjct: 904 ERGSPQ-------------DLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE 950
Query: 1619 QVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLG 1678
+ +P D I +L+P KY+ +F P++ +A T D+
Sbjct: 951 KNLP--EDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKT------- 1001
Query: 1679 ELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKD-GPQVVP-VEGHERSVTVTPLDAGRK 1736
L V + T +++R++W G+ ++ V ++ G Q+V V S + L
Sbjct: 1002 -LKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTT 1060
Query: 1737 YRFLLYGLL----GKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSV 1792
Y + + GK R G GTT +R PR L+ + T +S
Sbjct: 1061 YDITVLPIYKMGEGKLRQG----SGTTASRFK----------SPR---NLKTSDPTMSSF 1103
Query: 1793 GLSWTVPEGQFDSFVVQYKD-----RDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGL 1847
++W G+ + V + R G+ V P + + V + L YK+ ++G+
Sbjct: 1104 RVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT---VVLEELRAGTTYKVNVFGM 1160
Query: 1848 HHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHL---SWMVT 1904
G P+ G+E T T + T P G + A + + L SW +
Sbjct: 1161 FDGGESSPL------VGQEMT---TLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIG 1211
Query: 1905 EGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV------ 1958
F + + R +++ IG R I L+ D R L D K +
Sbjct: 1212 RANFRTVR-SFISRI--VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVAN 1268
Query: 1959 ----GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSL-SWTVPEGQ 2013
G + + + + + A P + ++G L + D + S + +
Sbjct: 1269 LPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR-KIGVLITDGKSQDDVEAPSKKLKDEG 1327
Query: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073
+ F + +N D E + + +PD + N+ F R+ + +
Sbjct: 1328 VELFAIGIKNAD-----------EVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLC 1376
Query: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD-R 2132
S++ P E P L ++ + S +SWT P D + V+Y
Sbjct: 1377 N-----------SVKGPGDLEAP--SNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS 1423
Query: 2133 DGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPL 2192
G+ Q V E+ + L+P +Y +++Y + E P+ T P P+
Sbjct: 1424 GGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLP------VPV 1477
Query: 2193 AKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFK----NGDGQPKAVRVPGHEDGVT 2248
L + D+ ++ + W P G +++ +K +PK VR+ + +
Sbjct: 1478 VSLN-----IYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQ 1531
Query: 2249 ISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEE 2308
++ L P+ +Y + + PV+ +T P PR ++
Sbjct: 1532 LTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLP--------------------LPRPQD 1571
Query: 2309 LTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYK 2368
L + D T ++++ W G+ ++V+YK + K V E ++ L Y
Sbjct: 1572 LKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYT 1631
Query: 2369 MNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLS 2428
+++ H PV TA E P P +++ E E G S
Sbjct: 1632 VSVSAVHDEGESPPV-----TAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYR 1686
Query: 2429 LSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2488
++W P G D + G+E+ + L P Y++ + ++
Sbjct: 1687 ITWA-PFGSSDKMETI------------LNGDENTLVFENLNPNTIYEVSITAIYP---- 1729
Query: 2489 GPVSTVGVTAPQEDVDETPSPTEPGTEAPGP---PEEPLLG--ELTVTGSSPDSLSLSWT 2543
DE+ S G+E P + P G L V ++ +SL++ W
Sbjct: 1730 ---------------DESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774
Query: 2544 VPQGRFDSFTVQYKDR--DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGP 2601
GR + + Y+ +G Q +GG+++ V ++ L+P Y + + L+ G
Sbjct: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGR 1834
Query: 2602 VSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQ 2661
++ G T+ P T + L + D + +L++ W EG + +
Sbjct: 1835 MTGRGKTK---------PLNT--------VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLF 1877
Query: 2662 YRNGDGQPKA-VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEET 2720
Y G P+ V +PG+ + + L+PD Y + + + G S G T
Sbjct: 1878 YAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRG-- 1935
Query: 2721 PSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDG-RP-Q 2778
L + V +P+SL + W G + V Y DG RP +
Sbjct: 1936 -----------------LARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978
Query: 2779 VMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPE 2838
+ V G V + L P Y ++L L+ P G T
Sbjct: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL--------------- 2023
Query: 2839 PPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQP--KVVRVPGHEDGVT 2896
P + PR L V T +SLS++W +G + + Y G P + VPG + V
Sbjct: 2024 PRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
Query: 2897 ISGLEPDHKYKMNLYGFH----GGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPL 2952
+ L+PD YK+ + + GG G +G+ PP+
Sbjct: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLL------------------PPQNIH 2123
Query: 2953 LGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGC 3012
+ + T +SW + + YK + GE + T+ L P
Sbjct: 2124 ISDEWYT-----RFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPST 2178
Query: 3013 KYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPD 3072
Y +++Y ++ G++ P + TT + + +L D
Sbjct: 2179 TYDVNVYAQYDS---------GLSVPLTDQGTTLYL-----------NVTDLKTYQIGWD 2218
Query: 3073 SLSLSWMVPEGQFDHFLVQYRNGDG-QPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHG 3131
+ + W P + ++ DG + + + V G E +GL PD Y + ++
Sbjct: 2219 TFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF-VQT 2276
Query: 3132 GQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLL--GELTVTGSSPDSLSL---SWTV 3186
GP + V E T PTE TE P P P + G+ D + L SW++
Sbjct: 2277 PNLEGP--GVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSI 2334
Query: 3187 PQGRFD 3192
F+
Sbjct: 2335 GDDNFN 2340
Score = 207 bits (526), Expect = 2e-52
Identities = 267/1125 (23%), Positives = 441/1125 (39%), Gaps = 148/1125 (13%)
Query: 2947 PPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEES-EVTV 3005
PP++ E+T G +W+ S+ + YK+ G +V V S V +
Sbjct: 634 PPKDLSFSEVTSYG-----FKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVL 688
Query: 3006 GGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELT 3065
L+P Y +++ +E G + P ETT+ V PR L
Sbjct: 689 SSLKPETLYLVNVTAEYED---------GFSIPLAGEETTEEVKGA-------PR--NLK 730
Query: 3066 VTDATPDSLSLSWMVPEGQFDHFLVQYRN-GDGQPKAVRVPGHEDGVTISGLEPDHKYKM 3124
VTD T DS ++W G+ + + YR G+ + V P ++ T+ L PD KY++
Sbjct: 731 VTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEV 790
Query: 3125 NLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSW 3184
++ + P++ TEE +P + L V+ + ++ LSW
Sbjct: 791 SVIPEYFSGPGTPLTGNAATEEVRGNPRD----------------LRVSDPTTSTMKLSW 834
Query: 3185 TVPQGRFDSFTVQYKD-RDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGP 3243
+ G+ + V Y G+ Q V VRG+ + + GL+ G +Y + + L+
Sbjct: 835 SGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDA 894
Query: 3244 VSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQ----YRDAQG 3299
+ G T L +L +T S+G WT A G + V Y D
Sbjct: 895 LFGEGTT------LEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDT 948
Query: 3300 QPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEART--APDTKPSPRLG 3357
+ +P D + L P KY+ +F + P+ +A T + D+K
Sbjct: 949 GEKNLPE--DAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKT----- 1001
Query: 3358 ELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKD-GRLQVVPVAANQREVTVQGLEPSRK 3416
L V + T +++ ++W G+ ++ V Y+ G+ V V ++ L+P
Sbjct: 1002 -LKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTT 1060
Query: 3417 YRFLLYGL----SGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQG 3472
Y + + G+ R G TTA K P L ++ T SS R++W A G
Sbjct: 1061 YDITVLPIYKMGEGKLRQG----SGTTASRFKS--PR--NLKTSDPTMSSFRVTWEPAPG 1112
Query: 3473 PFDSFVVQYRDTDGQPRA--VPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSAL 3530
+ V + T R + V TV +E+L G YK ++G+ G P+
Sbjct: 1113 EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQ 1172
Query: 3531 GMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRL---SWSVAQG------PF 3581
MT + T P L+ G+ +T D + L SWS+ + F
Sbjct: 1173 EMTTLSDTTVMPILSS-----------GMECLTRAEADIVLLVDGSWSIGRANFRTVRSF 1221
Query: 3582 DSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKR-----LGPLSA 3636
S +V+ D P+ + + Q SG +P T ++ H K+ + L
Sbjct: 1222 ISRIVEVFDIG--PKRVQIALAQ----YSG-DPRTEWQL---NAHRDKKSLLQAVANLPY 1271
Query: 3637 EG---TTGLA------PAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDS---FL 3684
+G TG+A +T RPR ++ V +T + + EAP L
Sbjct: 1272 KGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVL-ITDGKSQDDVEAPSKKLKDEGVEL 1330
Query: 3685 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLR--SGTLYSLTLYGLRGPHKADS 3742
G+ + +E L+ P H+ + D S + LT+ + +S
Sbjct: 1331 FAIGIKNADEVE------LKMIATDPDDTHAYNVADFESLSRIVDDLTI------NLCNS 1378
Query: 3743 IQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVD 3802
++G LE+P +L SE S +V+W PP D +KV Y GG+ Q V
Sbjct: 1379 VKGPGD-----LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVS 1433
Query: 3803 GQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLH 3862
+ L+ L P Y V V SV E SEPL G T+P L ++ +
Sbjct: 1434 RMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQ 1493
Query: 3863 WKP---PQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNL 3919
W+P + +Y P + + D L DLV +T Y TV+ +
Sbjct: 1494 WQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLT 1553
Query: 3920 TSPASI-TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLP 3978
+ P ++ T L P+DL+ ++VT T + W P + Y++ + TP +E+ +
Sbjct: 1554 SEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVD 1613
Query: 3979 GGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIP 4023
TS L LF T Y + A+ + PPV+ TT + P
Sbjct: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAP 1658
Score = 169 bits (428), Expect = 5e-41
Identities = 199/953 (20%), Positives = 360/953 (37%), Gaps = 96/953 (10%)
Query: 3064 LTVTDATPDSLSLSWMVPEGQFDHFLVQYRN-GDGQPKAVRVPGHEDGVTISGLEPDHKY 3122
L +++ T S +SW P D + V+Y G+ + V E + L+P+ +Y
Sbjct: 1391 LVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEY 1450
Query: 3123 KMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSL 3182
+N+Y V E+E P + + + P + L + P ++ +
Sbjct: 1451 VVNVYS--------------VVEDEYSEPLKGTEKTLPVP----VVSLNIYDVGPTTMHV 1492
Query: 3183 SWTVPQGRFDSFTVQYKD----RDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEG 3238
W P G + + YK +P+ VR+ +++ + L P +Y + + +
Sbjct: 1493 QWQ-PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHD 1551
Query: 3239 QRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQ 3298
PV+ +T PLP P +L + VT ++ + W G ++V+Y+ +
Sbjct: 1552 LTSEPVTVREVTLPLPRPQ-------DLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 1604
Query: 3299 GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGE 3358
+ V V + ++ L Y + + + PV + T P P+
Sbjct: 1605 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPT----N 1660
Query: 3359 LTVTDATPDSVGLSWTVPEGEFDSFVVQYKD--KDGRLQVVPVAANQREVTVQGLEPSRK 3416
L +T+ T + +W + + + + +++ + + ++ + + L P+
Sbjct: 1661 LKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTI 1719
Query: 3417 YRFLLYGL-SGRKRLGPISADSTTAPLEKELPPHLG--ELTVAEETSSSLRLSWTVAQGP 3473
Y + + + T P+ P G L V TS+SL + W A G
Sbjct: 1720 YEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGR 1779
Query: 3474 FDSFVVQYRDT--DGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALG 3531
+ + Y+ + +G + + Q +V ++ L+P Y + L G ++ G
Sbjct: 1780 VQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRG 1839
Query: 3532 MTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDT 3591
T P L V D + ++ + W A+G + + Y
Sbjct: 1840 KTKPLNTVRN------------------LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPA 1881
Query: 3592 NGQPQALL-VDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSE 3650
G P+ L+ + G+ + ++ L+P T Y + P+ EG G+TS+
Sbjct: 1882 AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVV---------PVYTEGD-----GGRTSD 1927
Query: 3651 ESRPRLSQLS----VTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRE 3706
R + L+ V + T +SL + W+ PG + + + P T RP
Sbjct: 1928 TGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS-PVDGT-----RP--SES 1979
Query: 3707 LMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIR 3766
++VPG L L TLYS+ L L + + RTL PR+L+
Sbjct: 1980 IVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR--SGPRNLRVFGET 2037
Query: 3767 ETSAKVNWMPPPSRADSFKVSYQLADGGE-PQSVQVDGQARTQKLQGLIPGARYEVTVVS 3825
S V W +++ Y G + V G+ LQ L P Y++TV++
Sbjct: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097
Query: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAV---LHWKPPQNPVDTYDVQVTAPGA 3882
V + LTG TV P Q +++++ + + W P +PV Y + G+
Sbjct: 2098 VYEDGDGGHLTGNGRTVGLLPPQ--NIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS 2155
Query: 3883 PPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEV 3942
G Y LH+L T Y V L+ P + TT DL+ ++
Sbjct: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQI 2215
Query: 3943 TPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSY 3995
T + W+ + L G + QEI + G TSH GL P T Y
Sbjct: 2216 GWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDY 2268
Score = 156 bits (395), Expect = 4e-37
Identities = 230/1142 (20%), Positives = 410/1142 (35%), Gaps = 167/1142 (14%)
Query: 1256 PEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQG-QPQAVPVAGDENEV 1314
P LE P L ++ T S R+SWT D + V+Y G + Q V+ E
Sbjct: 1382 PGDLEAP--SNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETST 1439
Query: 1315 TVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPL 1374
+ L P+ +Y +N+Y + + P KT P V
Sbjct: 1440 VLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-------------------- 1479
Query: 1375 LGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD----RDGRPRAVRVGGKESEVTVGGL 1430
L + P ++ + W P G + + YK RP+ VR+G +++ + L
Sbjct: 1480 ---LNIYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDL 1535
Query: 1431 EPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSV 1490
P +Y + + + PV+ VT P PR +L + DVT +++
Sbjct: 1536 VPNTEYAVTVQAVLHDLTSEPVTVREVTLPL-------------PRPQDLKLRDVTHSTM 1582
Query: 1491 GLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQR 1550
+ W G+ +IV+YK + + V V + ++ +L + Y +++ +HD
Sbjct: 1583 NVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE 1642
Query: 1551 MGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQ 1610
P++ T P+ PAP L +T++T + +W + + +
Sbjct: 1643 SPPVTAQETTRPV-PAPT-------------NLKITEVTSEGFRGTWDHGASDVSLYRIT 1688
Query: 1611 YKDRDGQPQVVPVA-ADQREVTIPDLEPSRKYKFLLFGIQDGKRRSP--VSVEAKTVARG 1667
+ ++ + D+ + +L P+ Y+ + I + S + E
Sbjct: 1689 WAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILT 1748
Query: 1668 DASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG---PQVVPVEGHER 1724
+P + PR L V + T +SL + W G+ + + ++ G Q + G +
Sbjct: 1749 TQAPKSGPR--NLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQN 1806
Query: 1725 SVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQV 1784
SV + L Y + L G +T G T+ + + L+V
Sbjct: 1807 SVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTV--------------RNLRV 1852
Query: 1785 TTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQP-QVVPVEGSLREVSVPGLDPAHRYKLL 1843
+ +++ + W EG + + Y G P ++VP+ G+ + L P Y +
Sbjct: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVT 1912
Query: 1844 LYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMV 1903
+ ++ G S T R + V T ++L + W
Sbjct: 1913 VVPVYTEGDGGRTSDTGRTLMRGLAR----------------NVQVYNPTPNSLDVRWDP 1956
Query: 1904 TEGEFDSFEIQYTDRDG--QLQMVRIGGDRNDITLSGLESDHRYLVTLYG-FSDGKHVGP 1960
G + + Y+ DG + + + G+ + L L D Y V L +SDG
Sbjct: 1957 APGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDG----- 2011
Query: 1961 VHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQ 2020
E PS P P PR L V T +SLS++W +G + +
Sbjct: 2012 ----------EGNPS-PAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRII 2058
Query: 2021 YRNGDGQP--KAVRVPGHEEGVTISGLEPDHKYKMNLYGFH----GGQRMGPVSVVGVTA 2074
Y G P + VPG V + L+PD YK+ + + GG G VG+
Sbjct: 2059 YSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLP 2118
Query: 2075 AEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDG 2134
+ + ++ +SW + + YK
Sbjct: 2119 PQ-----------------------NIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS 2155
Query: 2135 RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAK 2194
+ GE + T+ L P Y +++Y ++ P++ G T
Sbjct: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT-----------LY 2204
Query: 2195 LRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDG-QPKAVRVPGHEDGVTISGLE 2253
L + + I D+ + W+ P + ++ DG + + + V G E +GL
Sbjct: 2205 LNVTDLKTYQIGWDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263
Query: 2254 PDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPP--IKPRLEELTV 2311
PD Y + ++ GP +V K E A TEPPTP PP I P +
Sbjct: 2264 PDTDYGVTVF-VQTPNLEGPGVSVKEHTTVKPTE---APTEPPTPPPPPTIPPARDVCKG 2319
Query: 2312 TDATPDSLS-LSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMN 2370
A L+ SW++ + F+ + N G G + E +++K+N
Sbjct: 2320 AKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLN 2379
Query: 2371 LY 2372
Y
Sbjct: 2380 TY 2381
Score = 154 bits (390), Expect = 1e-36
Identities = 236/1091 (21%), Positives = 391/1091 (35%), Gaps = 181/1091 (16%)
Query: 1056 PGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKD-RDGQPQVVPVEGPQRS 1114
PG P L +++RT S + WT P D + ++Y G+ Q V + S
Sbjct: 1382 PGDLEAP---SNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETS 1438
Query: 1115 AVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDS 1174
V+ L P +Y +Y V + PL K LP + +L + D P +
Sbjct: 1439 TVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP---------VVSLNIYDVGPTT 1489
Query: 1175 LHLSWTVPEGQFDTFMVQYR----DRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGI 1230
+H+ W P G +++ Y+ RP+ V + ++ L P+ +Y T+ +
Sbjct: 1490 MHVQWQ-PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 1548
Query: 1231 ANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDS 1290
+ P+T T P PRP+ +L + VT ++ + W G
Sbjct: 1549 LHDLTSEPVTVREVTLP-----LPRPQ--------DLKLRDVTHSTMNVFWEPVPGKVRK 1595
Query: 1291 FMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQ 1350
++V+YK + + V V E ++ L Y +++ + P + T P
Sbjct: 1596 YIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP- 1654
Query: 1351 EDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRD 1410
P+PT L + E E G G+S SL P GS D
Sbjct: 1655 -----VPAPTNL--KITEVTSEGFRGTWD-HGASDVSLYRITWAPFGSSDKM-------- 1698
Query: 1411 GRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP--A 1468
+ G E+ + L P Y++ + ++ P + E T P
Sbjct: 1699 ----ETILNGDENTLVFENLNPNTIYEVSITAIY------PDESESDDLIGSERTLPILT 1748
Query: 1469 TESPLE-PRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDK--DGQPQVVPVAADQR 1525
T++P PR L V + T NS+ + W G+ + + Y+ +G Q + Q
Sbjct: 1749 TQAPKSGPR--NLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQN 1806
Query: 1526 EVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTV 1585
V + L+P+ Y + + L+ G ++ T PL + L V
Sbjct: 1807 SVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL--------------NTVRNLRV 1852
Query: 1586 TDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQP-QVVPVAADQREVTIPDLEPSRKYKFL 1644
D + ++ + W EG + + Y G P ++VP+ + + +L+P Y
Sbjct: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVT 1912
Query: 1645 LFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSF 1704
+ + S +T+ RG A + V +PTP+SL + W G +
Sbjct: 1913 VVPVYTEGDGGRTSDTGRTLMRGLAR--------NVQVYNPTPNSLDVRWDPAPGPVLQY 1964
Query: 1705 VVQFKDKDG---PQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEA 1761
V + DG + + V G+ R V + L Y L L P A G T
Sbjct: 1965 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 2024
Query: 1762 RSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQP--QV 1819
RS PR L+V T NS+ ++W +G + + Y G P +
Sbjct: 2025 RSG-----------PR---NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY 2070
Query: 1820 VPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAG---------REETET 1870
V G V + L P YK+ + ++ G ++ T G +E T
Sbjct: 2071 TTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYT 2130
Query: 1871 ETTAPTPPAPEPHLG--------------ELTVEEATSHTLH------------------ 1898
P+P P LG E V E TS+TLH
Sbjct: 2131 RFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDS 2190
Query: 1899 -LSWMVTEG----------------EFDSFEIQYTDR-------------DG-QLQMVRI 1927
LS +T+ +D+F ++++ DG + Q + +
Sbjct: 2191 GLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITV 2250
Query: 1928 GGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHV-EALTVPEEEKPSEPPTATPEPPI 1986
G +GL D Y VT++ + V V E TV E P+EPPT P P I
Sbjct: 2251 RGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTI 2310
Query: 1987 KPRLGELTVTDATPDSLS-LSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGL 2045
P A L+ SW++ + F+ + N G + G +
Sbjct: 2311 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSD 2370
Query: 2046 EPDHKYKMNLY 2056
E ++K+N Y
Sbjct: 2371 EVKSEFKLNTY 2381
Score = 139 bits (351), Expect = 5e-32
Identities = 155/653 (23%), Positives = 260/653 (39%), Gaps = 58/653 (8%)
Query: 3385 VQYKDKDGRLQVVPVA-ANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLE 3443
++ ++ D + V V A + E+ P+ + F + +R+ S +E
Sbjct: 562 IKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIE 621
Query: 3444 KEL---------PPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVA 3494
+EL PP +L+ +E TS + +W+ A S+ + Y++ G V
Sbjct: 622 QELAAIKKKAYVPPK--DLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE 679
Query: 3495 -ADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPE 3553
A +V + L+P Y + +TA ED + LA E
Sbjct: 680 PASSTSVVLSSLKPETLY-----------------LVNVTAEYEDGFSIPLAGEETTEEV 722
Query: 3554 EPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGL 3612
+ L VTD T DS +++W+ A G + + Y G+ + + +Q + + L
Sbjct: 723 KGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENL 782
Query: 3613 EPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLN 3672
P T Y + + PL+ T EE R L V+D TTS+++L+
Sbjct: 783 IPDTKYEVSVIPEYFSGPGTPLTGNAAT---------EEVRGNPRDLRVSDPTTSTMKLS 833
Query: 3673 WEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLY 3732
W PG +L+ + + + E+ V G + VL+ L+ GT Y+L++
Sbjct: 834 WSGAPGKVKQYLVTYTPVAGGETQ---------EVTVRGDTTNTVLQGLKEGTQYALSVT 884
Query: 3733 GLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQ-LA 3791
L D++ G TL SP+DL +I +TS W P ++VS++ L
Sbjct: 885 ALYASGAGDALFGEGTTLEE-RGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLY 943
Query: 3792 DGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTT-VPDGPTQLR 3850
D + + A ++ L P +Y ++V + E EPLTG TT + L+
Sbjct: 944 DDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLK 1003
Query: 3851 ALNLTEGFAVLHWKPPQNPVDTYDVQVTAPG-APPLQAETPGSAVDYPLHDLVLHTNYTA 3909
TE + WKP V Y V G + A+ P + L L T Y
Sbjct: 1004 VDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDI 1063
Query: 3910 TVRGL--RGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHT 3967
TV + G S T + ++PR+L+ + T + +TW P GY ++FH
Sbjct: 1064 TVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHP 1123
Query: 3968 PGGQNQ--EILLPGGITSHQLLGLFPSTSYNARLQAMW-GQSLLPPVSTSFTT 4017
G + E+++ + L L T+Y + M+ G P V TT
Sbjct: 1124 TGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTT 1176
Score = 132 bits (333), Expect = 6e-30
Identities = 229/1145 (20%), Positives = 404/1145 (35%), Gaps = 168/1145 (14%)
Query: 1149 LPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRD-RDGRPQVVPVEG 1207
L S PG NL +++ T S +SWT P D + V+Y G+ Q V
Sbjct: 1375 LCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSR 1434
Query: 1208 PERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267
E S V+ L P+ +Y ++ + + PL T P P++ L
Sbjct: 1435 METSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLP-------------VPVV-SL 1480
Query: 1268 TVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQG----QPQAVPVAGDENEVTVPGLDPDR 1323
+ V P ++ + W G +++ YK + +P+ V + N++ + L P+
Sbjct: 1481 NIYDVGPTTMHVQWQPVGGA-TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNT 1539
Query: 1324 KYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGS 1383
+Y + + + P +V T P P P +L VT S
Sbjct: 1540 EYAVTVQAVLHDLTSEPVTVREVTLP------LPRPQDLKLR-------------DVTHS 1580
Query: 1384 SPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGL 1443
++++FW G + V+YK + + V V E+ ++ L Y + + +
Sbjct: 1581 ---TMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAV 1637
Query: 1444 HEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDS 1503
H+ PV+A QE T P P L +T+VT +W
Sbjct: 1638 HDEGESPPVTA-------QETTRPV------PAPTNLKITEVTSEGFRGTWDHGASDVSL 1684
Query: 1504 FIVQYKDKDGQPQVVPVA-ADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAP 1562
+ + + ++ + D+ + NL P Y++++ ++ + +I +
Sbjct: 1685 YRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDE--SESDDLIGSER 1742
Query: 1563 LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQV 1620
P T+A P PR L V + T +S+ + W G + + Y+ +G Q
Sbjct: 1743 TLPILTTQA--PKSGPR--NLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 1798
Query: 1621 VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL 1680
+ Q V + L+P Y + + P + RG P R L
Sbjct: 1799 TTIGGRQNSVVLQKLKPDTPYTITVSSLY------PDGEGGRMTGRGKTKPLNTVR--NL 1850
Query: 1681 WVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG--PQVVPVEGHERSVTVTPLDAGRKYR 1738
V DP+ +L + W EG + + + G ++VP+ G+ + L Y
Sbjct: 1851 RVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYT 1910
Query: 1739 FLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTV 1798
+ + + G + G T R L +QV T NS+ + W
Sbjct: 1911 VTVVPVYTEGDGGRTSDTGRTLMRG--------------LARNVQVYNPTPNSLDVRWDP 1956
Query: 1799 PEGQFDSFVVQYKDRDG--QPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPI 1856
G + V Y DG + + V G+ R V + L P Y +
Sbjct: 1957 APGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYS--------------V 2002
Query: 1857 SAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT 1916
+ VA+ + E + T P P L V T+++L ++W +G + I Y+
Sbjct: 2003 NLVALYSDGEGNPSPAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYS 2060
Query: 1917 DRDGQL--QMVRIGGDRNDITLSGLESDHRYLVT---LYGFSDGKHV-GPVHVEALTVPE 1970
G + + G RN++ L L+ D Y +T +Y DG H+ G L P+
Sbjct: 2061 PTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQ 2120
Query: 1971 EEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSW-TVPEGQFDHFLVQYRNGDGQPK 2029
+ ++D +SW P + +V G +P
Sbjct: 2121 ---------------------NIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPM 2159
Query: 2030 AVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEA 2089
V G T+ L P Y +N+Y + P++ G T T
Sbjct: 2160 EAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVT---------- 2208
Query: 2090 PEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDG-RPQVVRVGGEESEV 2148
+L D+ + W+ P S+ ++ DG R Q + V G E+
Sbjct: 2209 ----------DLKTYQIGWDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSH 2257
Query: 2149 TVGGLEPGRKYKMHLYGLHEGRRVGPVSAV-------GVTAPEEESPDAPLAKLRLGQMT 2201
GL P Y + ++ + GP +V AP E P + +
Sbjct: 2258 CFTGLSPDTDYGVTVF-VQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDV 2316
Query: 2202 VRDITSDSLSL---SWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKY 2258
+ +D + L SW++ + F+ + N G + G + E ++
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376
Query: 2259 KMNLY 2263
K+N Y
Sbjct: 2377 KLNTY 2381
Score = 98.2 bits (243), Expect = 2e-19
Identities = 131/632 (20%), Positives = 240/632 (37%), Gaps = 108/632 (17%)
Query: 2519 PPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQES-KVTV 2577
PP++ E+T G +W+ S+ + YK+ G + V S V +
Sbjct: 634 PPKDLSFSEVTSYG-----FKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVL 688
Query: 2578 RGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMT 2637
L+P Y +++ +E P++ TE+ +K L +T
Sbjct: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEE----------------VKGAPRNLKVT 732
Query: 2638 DATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 2696
D T DS ++WT G+ + + YR G+ + V P ++ T+ L PD KY++++
Sbjct: 733 DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
Query: 2697 YGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSW 2756
+ P++ G A EE +P +L P + ++ LSW
Sbjct: 793 IPEYFSGPGTPLT--GNAATEEVRGNPRDLRVSDP----------------TTSTMKLSW 834
Query: 2757 TIPQGHFDSFTVQYKD-RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGP 2815
+ G + V Y G Q + VRG+ + + GL+ G +Y + + L+
Sbjct: 835 SGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDA 894
Query: 2816 VSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQ 2875
+ G T +E + Q +L D T S+ W G + V
Sbjct: 895 LFGEGTTLEERGSPQ----------------DLVTKDITDTSIGAYWTSAPGMVRGYRVS 938
Query: 2876 YRN--GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEE 2933
+++ D +P I L+P+ KY+ ISV ++ E
Sbjct: 939 WKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR--------------ISVFATYSSGEG 984
Query: 2934 TPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRD-GRPQ 2992
P + +TE + + L V + +++ ++W G+ ++ V Y+ G+
Sbjct: 985 EPLTGDATTELSQDSK-----TLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQM 1039
Query: 2993 VVRVRGEESEVTVGGLEPGCKYK---MHLYGLHEGQ-RVGPVSAVGVTAPKDEAETTQAV 3048
V +V + + L+P Y + +Y + EG+ R G G TA + ++
Sbjct: 1040 VAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS----GTTASRFKS------ 1089
Query: 3049 PTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYR-NGDGQPKAVRVPG- 3106
PR L +D T S ++W G+ + V + GD + V G
Sbjct: 1090 ----------PR--NLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
Query: 3107 HEDGVTISGLEPDHKYKMNLYGFHGGQRVGPV 3138
+++ V + L YK+N++G G P+
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPL 1169
Score = 69.3 bits (168), Expect = 8e-11
Identities = 132/624 (21%), Positives = 216/624 (34%), Gaps = 92/624 (14%)
Query: 733 SCVCKDGYAGEDCG----EEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTE 788
S + DG G G + + T+ +R++ +T+ W A G Y++ + P
Sbjct: 1824 SSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG 1883
Query: 789 GASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDG-PQDLR 847
G P +P + + R L P Y VTV + G S T T++ G ++++
Sbjct: 1884 G--PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQ 1941
Query: 848 VVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVR--LEVPPEADGTLLTDLMPGVEYV 905
V TP +L++ W V ++ V Y R + VP L L+P Y
Sbjct: 1942 VYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYS 2001
Query: 906 VTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGE 965
V + A P+ + T P SGP
Sbjct: 2002 VNLVALYSDGEGNPSPAQGRT-------------LPRSGPRN------------------ 2030
Query: 966 LRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHE-EVLPGDVRQALVPPPPPGT 1024
LRV G + T L V W +++ G E +PG ++ P P T
Sbjct: 2031 LRVFG-ETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 2089
Query: 1025 PYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSG--PPRLGELTVTDRTSDSLLLRW 1082
PY++++ V G G + + G++ G PP+ + ++D + W
Sbjct: 2090 PYKITVIAVYEDGDG-------GHLTGN----GRTVGLLPPQ--NIHISDEWYTRFRVSW 2136
Query: 1083 TVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPL 1142
+ I YK + G S + +L+P Y +Y PL
Sbjct: 2137 DPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPL 2196
Query: 1143 VAEAKILPQSDPSPGTPPHLGNLWVTDPTP-----DSLHLSWTVPEGQFDTFMVQYRDRD 1197
+ GT +L VTD D+ + W+ P ++ ++ D
Sbjct: 2197 TDQ-----------GTTLYLN---VTDLKTYQIGWDTFCVKWS-PHRAATSYRLKLSPAD 2241
Query: 1198 G-RPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGP-------LTADGTTAPER 1249
G R Q + V G E S + L PD Y T+F + GP T T AP
Sbjct: 2242 GTRGQEITVRGSETSHCFTGLSPDTDYGVTVF-VQTPNLEGPGVSVKEHTTVKPTEAPTE 2300
Query: 1250 KEEPPRPEFLEQPLLGELTVTGVTPDSLRL---SWTVAQGPFDSFMVQYKDAQGQPQAVP 1306
PP P + G D + L SW++ F+ + + G +
Sbjct: 2301 PPTPPPPPTIPP---ARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEIS 2357
Query: 1307 VAGDENEVTVPGLDPDRKYKMNLY 1330
AG + + ++K+N Y
Sbjct: 2358 PAGIQVSFVQYSDEVKSEFKLNTY 2381
Score = 47.0 bits (110), Expect = 4e-04
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Query: 3753 VLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSY-QLADGGEPQSVQVDGQARTQKLQ 3811
V+E P +L E+ K+NW P PS +KV + G ++ V Q T ++
Sbjct: 333 VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
Query: 3812 GLIPGARYEVTVVSVRGFEESEPLTGFLTTVP 3843
L Y+++V +++G SEP++ T P
Sbjct: 393 DLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424
Score = 44.3 bits (103), Expect = 0.003
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 3745 GTARTLSPV---LESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV 3801
G A LS + ++ P DL F I E + ++W P ++++ G + +
Sbjct: 13 GAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL 72
Query: 3802 DGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLT 3840
L L+P Y VT+ S EES P+ G LT
Sbjct: 73 SASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
Score = 42.0 bits (97), Expect = 0.013
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 765 VRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALR 824
V+ W P+P PV Y++ P T G S V + R L+ EYQ++V A++
Sbjct: 350 VKLNWNPSPSPVTGYKVILTPMTAG-SRQHALSVGPQTTTLSVRDLSADTEYQISVSAMK 408
Query: 825 GTSWGLPAS 833
G + P S
Sbjct: 409 GMTSSEPIS 417
Score = 41.2 bits (95), Expect = 0.022
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 27/110 (24%)
Query: 835 TITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADG-- 892
+I +D P DL + T+ + W +P VD +V Y R+ V P DG
Sbjct: 20 SIEAEVDPPSDLNFKIIDENTVHMSWAKP---VDP-IVGY--------RITVDPTTDGPT 67
Query: 893 -----------TLLTDLMPGVEYVVTVTA--ERGRAVSYPASVRANTGSS 929
TLL++L+P EYVVT+T+ E +V + TGSS
Sbjct: 68 KEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSS 117
Score = 40.8 bits (94), Expect = 0.029
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 748 EVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQ 807
EV + +++E TV W P+ Y I PTT+G + FT ++ + +
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
Query: 808 RGLAPGQEYQVTVRALRGTSWGLPASKTIT 837
L P EY VT+ + +P +T
Sbjct: 84 --LVPETEYVVTITSYDEVEESVPVIGQLT 111
Score = 38.5 bits (88), Expect = 0.14
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Query: 839 MIDGPQDLRVVAVTPTTLELGWLRPQAEVDRF--VVSYVSAGNQRVRLEVPPEADGTLLT 896
+++ P +L + V+ ++L W + V + +++ ++AG+++ L V P+ +
Sbjct: 333 VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
Query: 897 DLMPGVEYVVTVTAERGRAVSYPASVRANT 926
DL EY ++V+A +G S P S+ T
Sbjct: 393 DLSADTEYQISVSAMKGMTSSEPISIMEKT 422
Score = 35.8 bits (81), Expect = 0.93
Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 3842 VPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVT--APGAPPLQAETPGSAVDYPLH 3899
V + P+ L A+ ++ + L+W P +PV Y V +T G+ +
Sbjct: 333 VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
Query: 3900 DLVLHTNYTATVRGLRGPNLTSPASI 3925
DL T Y +V ++G + P SI
Sbjct: 393 DLSADTEYQISVSAMKGMTSSEPISI 418
Score = 35.0 bits (79), Expect = 1.6
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Query: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGY--LLSFHTPGGQNQEILLPGGITSHQLLG 3988
+E P +L A EV+ + L W P GY +L+ T G + + + T+ +
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
Query: 3989 LFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRI 4022
L T Y + AM G + P+S T +++
Sbjct: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKV 427
Score = 34.3 bits (77), Expect = 2.7
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 4/120 (3%)
Query: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFH-TPGGQNQEILLPGGITSHQLLGL 3989
++ P DL K + T ++W +P GY ++ T G +E L T L L
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSEL 84
Query: 3990 FPSTSYNARLQAMWGQSLLPPVSTSFT--TGGLRIPFPRDCGE-EMQNGAGASRTSTIFL 4046
P T Y + + PV T TG P + G+ E+Q + ++ T +FL
Sbjct: 85 VPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFL 144
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 260 bits (664), Expect = 2e-68
Identities = 224/736 (30%), Positives = 275/736 (37%), Gaps = 231/736 (31%)
Query: 158 CEPGWGGP-TCSDPTDA------EIPPSSPPSASGSCPDDCNDQG--------RCVRGRC 202
CE W GP TC PT ++ + C +G CV GRC
Sbjct: 55 CERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRC 114
Query: 203 V------CFPGYTGPSCG-------W-PSC--PGDCQGRGRC--VQGVCVCRAGFSGPDC 244
V C PG+ G C W P C P C C GVC C +G P+C
Sbjct: 115 VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNC 174
Query: 245 SQRSCP----RGCSQRGRCEG-------GRCVCDPGYTGDDCGMRSCPRG-----CSQRG 288
Q P C R +C G G C C TG C + SC +G C
Sbjct: 175 LQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDV-SCSQGTSGFFCPSTH 233
Query: 289 RCEN--------GRCVCNPGYTGEDCGVRSCPRG-----CSQRGRCKD--------GRCV 327
C+N G C C PG+ G C + CP G CSQ RC + G+C
Sbjct: 234 SCQNGGVFQTPQGSCSCPPGWMGTICSL-PCPEGFHGPNCSQECRCHNGGLCDRFTGQCR 292
Query: 328 CDPGYTGEDCGTRSCP-----------WDCGEGGRC--VDGRCVCWPGYTGEDCSTRTCP 374
C PGYTG+ C CP DC RC +G C+C G+TG+ C+ R CP
Sbjct: 293 CAPGYTGDRC-REECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCP 351
Query: 375 -----RDCRGRGRCE----------DGECICDTGYSGDDCGVRSCPGD-----------C 408
C+ C+ +GEC C G++G C SCP D C
Sbjct: 352 DGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-ESCPQDTHGPGCQEHCLC 410
Query: 409 NQRGRCE--DGRCVCWPGYTGTDCGSRACPRD-----CRGRGRCEN--------GVCVCN 453
G C+ G C C PGYTG C S CP D C R CEN G CVC
Sbjct: 411 LHGGVCQATSGLCQCAPGYTGPHCAS-LCPPDTYGVNCSARCSCENAIACSPIDGECVCK 469
Query: 454 AGYSGEDCGVRSCPG----DCRGRGRC--------ESGRCMCWPGYTGRDCGTRACPGDC 501
G+ +C V PG C +C ++G C C PG+ G C
Sbjct: 470 EGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC--------- 520
Query: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCE--DGVCVCDAGYSGEDCSTRSC 559
+ C G GE C S RC DC C+ G C C AG+ G C SC
Sbjct: 521 ---------QLPCPKGQFGEGCAS-RC--DCDHSDGCDPVHGRCQCQAGWMGARCHL-SC 567
Query: 560 PGG-----------CRGRGQCL--DGRCVCEDGYSGEDC---------GVRQCPNDCSQH 597
P G C+ G CL +G CVC G+ G C G R P C+ H
Sbjct: 568 PEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANH 627
Query: 598 GVC--QDGVCICWEGYVSEDCSIRTCP-----------SNCHGRGRC--EEGRCLCDPGY 642
C +G C C G+ DCS + CP CH G C ++G C+C G+
Sbjct: 628 SFCHPSNGTCYCLAGWTGPDCS-QPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGW 686
Query: 643 TGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELC--RA 700
TG C++G C +G G +C Q P CGP E C
Sbjct: 687 TG---------------HHCLEG---CPLGTFGANCSQ--------PCQCGPGEKCHPET 720
Query: 701 GQCVCVEGFRGPDCAI 716
G CVC G G C I
Sbjct: 721 GACVCPPGHSGAPCRI 736
Score = 236 bits (603), Expect = 3e-61
Identities = 209/689 (30%), Positives = 254/689 (36%), Gaps = 217/689 (31%)
Query: 123 GGCCPASAQAGT-GQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPP 181
G C P AQ G+ C + C+ C PG GP C P S P
Sbjct: 99 GFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDP 158
Query: 182 SA------SGSCPDDCND-----------QGRC---------VRGRCVCFPGYTGPSCGW 215
+ SG P +C Q RC G C C TGPSC
Sbjct: 159 KSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDV 218
Query: 216 PS--------CPG--DCQGRG--RCVQGVCVCRAGFSGPDCSQRSCPRG-----CSQRGR 258
CP CQ G + QG C C G+ G CS CP G CSQ R
Sbjct: 219 SCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICS-LPCPEGFHGPNCSQECR 277
Query: 259 CEG--------GRCVCDPGYTGDDCGMRSCPRG-----------CSQRGRC--ENGRCVC 297
C G+C C PGYTGD C CP G C+ RC NG C+C
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRC-REECPVGRFGQDCAETCDCAPDARCFPANGACLC 336
Query: 298 NPGYTGEDCGVRSCPRG-----CSQRGRC----------KDGRCVCDPGYTGEDCGTRSC 342
G+TG+ C R CP G C C +G C C PG+ G C SC
Sbjct: 337 EHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC-NESC 395
Query: 343 PWD-----------CGEGGRC--VDGRCVCWPGYTGEDCSTRTCPRD-----CRGRGRCE 384
P D C GG C G C C PGYTG C++ CP D C R CE
Sbjct: 396 PQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCAS-LCPPDTYGVNCSARCSCE 454
Query: 385 --------DGECICDTGYSGDDCGVRSCPG----DCNQRGRC--------EDGRCVCWPG 424
DGEC+C G+ +C V PG CN +C + G C C PG
Sbjct: 455 NAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPG 514
Query: 425 YTGTDCGSRACPRDCRGRG---RCE----------NGVCVCNAGYSGEDCGVRSCPG--- 468
+ G C CP+ G G RC+ +G C C AG+ G C + SCP
Sbjct: 515 WHGAHC-QLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHL-SCPEGLW 572
Query: 469 --------DCRGRGRC--ESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGF 518
C+ G C E+G C+C PG+ G C + C PG
Sbjct: 573 GVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSC------------------QRSCQPGR 614
Query: 519 TGEDCGSRRCPGDCRGHGLC--EDGVCVCDAGYSGEDCSTRSCPGG-----------CRG 565
G+ C P C H C +G C C AG++G DCS + CP G C
Sbjct: 615 YGKRC----VPCKCANHSFCHPSNGTCYCLAGWTGPDCS-QPCPPGHWGENCAQTCQCHH 669
Query: 566 RGQC--LDGRCVCEDGYSGEDCGVRQCP-----NDCSQHGVCQDGVCICWEGYVSEDCSI 618
G C DG C+C G++G C + CP +CSQ C G
Sbjct: 670 GGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGPG--------------- 713
Query: 619 RTCPSNCHGRGRCEEGRCLCDPGYTGPTC 647
CH E G C+C PG++G C
Sbjct: 714 ----EKCHP----ETGACVCPPGHSGAPC 734
Score = 213 bits (541), Expect = 4e-54
Identities = 184/610 (30%), Positives = 224/610 (36%), Gaps = 168/610 (27%)
Query: 80 PPSTGCGCPPGTEPPVLASEVQ------ALRVRLEILEELVKGLKEQC------TGGCCP 127
P S C CP G +PP A + R + C TG C
Sbjct: 158 PKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCD 217
Query: 128 ASAQAGTGQTDVRTL--CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASG 185
S GT + C GVF + +CSC PGW G CS P P+ S
Sbjct: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGF---HGPNCSQ 274
Query: 186 SCPDDCNDQGRCVR--GRCVCFPGYTGPSCGWPSCP-----------GDCQGRGRC--VQ 230
C C++ G C R G+C C PGYTG C CP DC RC
Sbjct: 275 EC--RCHNGGLCDRFTGQCRCAPGYTGDRCR-EECPVGRFGQDCAETCDCAPDARCFPAN 331
Query: 231 GVCVCRAGFSGPDCSQRSCPRG-----CSQRGRCE----------GGRCVCDPGYTGDDC 275
G C+C GF+G C+ R CP G C C+ G C C PG+ G C
Sbjct: 332 GACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC 391
Query: 276 GMRSCPR-----GCSQRGRC--------ENGRCVCNPGYTGEDCGVRSCPR-----GCSQ 317
SCP+ GC + C +G C C PGYTG C CP CS
Sbjct: 392 N-ESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHC-ASLCPPDTYGVNCSA 449
Query: 318 RGRCK--------DGRCVCDPGYTGEDCGTRSCP-----WDCGEGGRCV--------DGR 356
R C+ DG CVC G+ +C CP + C +C G
Sbjct: 450 RCSCENAIACSPIDGECVCKEGWQRGNCSV-PCPPGTWGFSCNASCQCAHEAVCSPQTGA 508
Query: 357 CVCWPGYTGEDCSTRTCPRDCRGRG---RCE----------DGECICDTGYSGDDCGVRS 403
C C PG+ G C CP+ G G RC+ G C C G+ G C + S
Sbjct: 509 CTCTPGWHGAHCQL-PCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHL-S 566
Query: 404 CPG-----------DCNQRGRC--EDGRCVCWPGYTGTDC---------GSRACPRDCRG 441
CP C G C E+G CVC PG+ G C G R P C
Sbjct: 567 CPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCAN 626
Query: 442 RGRC--ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPG 499
C NG C C AG++G DC + CP PG+ G +C + C
Sbjct: 627 HSFCHPSNGTCYCLAGWTGPDCS-QPCP-----------------PGHWGENC-AQTC-- 665
Query: 500 DCRGRGRC--VDGRCVCNPGFTGEDCGSRRCP-----GDCRGHGLC--------EDGVCV 544
C G C DG C+C G+TG C CP +C C E G CV
Sbjct: 666 QCHHGGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGPGEKCHPETGACV 724
Query: 545 CDAGYSGEDC 554
C G+SG C
Sbjct: 725 CPPGHSGAPC 734
Score = 207 bits (526), Expect = 2e-52
Identities = 178/618 (28%), Positives = 225/618 (36%), Gaps = 176/618 (28%)
Query: 297 CNPGYTGEDCGVRSCPRGCSQRGRC-KDGRCVCDPGYTGEDCGTRSCP--W--------D 345
C+ Y V C + C GRC +C C PG+ G+DC + P W
Sbjct: 91 CHGFYESRGFCVPLCAQECVH-GRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149
Query: 346 CGEGGRC--VDGRC-------------VCWPGYTGEDCSTRTCPRDCRGRGRC--EDGEC 388
CG C G C C PGY G C R C G C + G C
Sbjct: 150 CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRC---QCHG-APCDPQTGAC 205
Query: 389 ICDTGYSGDDCGVRSCPGD----CNQRGRCED--------GRCVCWPGYTGTDCGSRACP 436
C +G C V G C C++ G C C PG+ GT C S CP
Sbjct: 206 FCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTIC-SLPCP 264
Query: 437 R-----DCRGRGRCEN--------GVCVCNAGYSGEDCGVRSCP-----------GDCRG 472
+C RC N G C C GY+G+ C CP DC
Sbjct: 265 EGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCR-EECPVGRFGQDCAETCDCAP 323
Query: 473 RGRC--ESGRCMCWPGYTGRDCGTRACPG-----DCRGRGRC----------VDGRCVCN 515
RC +G C+C G+TG C R CP C+ C ++G C C
Sbjct: 324 DARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCL 383
Query: 516 PGFTGEDCGSRRCPGD-----CRGHGLC--------EDGVCVCDAGYSGEDCSTRSCPG- 561
PG+ G C + CP D C+ H LC G+C C GY+G C++ P
Sbjct: 384 PGWAGLHC-NESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDT 442
Query: 562 ---GCRGRGQC--------LDGRCVCEDGYSGEDCGVRQCPN-----------DCSQHGV 599
C R C +DG CVC++G+ +C V CP C+ V
Sbjct: 443 YGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV-PCPPGTWGFSCNASCQCAHEAV 501
Query: 600 C--QDGVCICWEGYVSEDCSIRTCPSNCHGRG---RCE----------EGRCLCDPGYTG 644
C Q G C C G+ C + CP G G RC+ GRC C G+ G
Sbjct: 502 CSPQTGACTCTPGWHGAHCQL-PCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMG 560
Query: 645 PTCATRMCP-----------ADCRGRGRCV--QGVCLCHVGYGGEDCGQEEPPA----SA 687
C CP C+ G C+ G C+C G+ G C + P
Sbjct: 561 ARCHL-SCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC 619
Query: 688 CPGGCGPRELCRA--GQCVCVEGFRGPDCAIQTCPG-----------DCRGRGECH--DG 732
P C C G C C+ G+ GPDC+ Q CP C G CH DG
Sbjct: 620 VPCKCANHSFCHPSNGTCYCLAGWTGPDCS-QPCPPGHWGENCAQTCQCHHGGTCHPQDG 678
Query: 733 SCVCKDGYAGEDCGEEVP 750
SC+C G+ G C E P
Sbjct: 679 SCICPLGWTGHHCLEGCP 696
Score = 99.4 bits (246), Expect = 7e-20
Identities = 67/195 (34%), Positives = 85/195 (43%), Gaps = 52/195 (26%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASG-SCPDDCN--DQGRCV--RGRCVCFPGYTG 210
C C+ GW G C S P G +C + C + G C+ G CVC PG+ G
Sbjct: 552 CQCQAGWMGARCH--------LSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRG 603
Query: 211 PSCGWPSCPG---------DCQGRGRC--VQGVCVCRAGFSGPDCSQRSCPRG-----CS 254
PSC PG C C G C C AG++GPDCSQ CP G C+
Sbjct: 604 PSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQ-PCPPGHWGENCA 662
Query: 255 QRGRC--------EGGRCVCDPGYTGDDCGMRSCPRG-----CSQRGRC--------ENG 293
Q +C + G C+C G+TG C + CP G CSQ +C E G
Sbjct: 663 QTCQCHHGGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGPGEKCHPETG 721
Query: 294 RCVCNPGYTGEDCGV 308
CVC PG++G C +
Sbjct: 722 ACVCPPGHSGAPCRI 736
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 253 bits (645), Expect = 4e-66
Identities = 211/721 (29%), Positives = 289/721 (40%), Gaps = 137/721 (19%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC- 213
TC C PG+ G C + S+P +G C D N R +C+C PG+TGP C
Sbjct: 479 TCLCMPGFKGVHCE--LEINECQSNPCVNNGQCVDKVN------RFQCLCPPGFTGPVCQ 530
Query: 214 -GWPSCPG-DCQGRGRCVQG----VCVCRAGFSGPDCSQR--SCPRGCSQRGRCEGG--- 262
C C +C+ C C GF+G C + +C G+C+ G
Sbjct: 531 IDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDS 590
Query: 263 -RCVCDPGYTGDDCG--MRSC-PRGCSQRGRC---ENG-RCVCNPGYTGEDCGVR--SCP 312
C+C+PGY G C + C C GRC NG +C C PG +G +C + C
Sbjct: 591 YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCA 650
Query: 313 RGCSQRGRCKDG----RCVCDPGYTGEDCG---TRSCPWDCGEGGRCVDG----RCVCWP 361
G C DG CVC PG+TG+ C C +G C++G RC+C
Sbjct: 651 SNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPE 710
Query: 362 GYTGEDCSTRT--CPRDCRGRGRCEDG----ECICDTGYSGDDCGV---RSCPGDCNQRG 412
G C ++ C + G C G +C+CD G+ G +C V C G
Sbjct: 711 GPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
Query: 413 RCED----GRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV----CVCNAGYSGEDC 461
C++ RC C G+ G +C C +G C + + C C Y+G++C
Sbjct: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Query: 462 G--VRSC-PGDCRGRGRC------ESGRCMCWPGYTGRDCG---TRACPGDCRGRGRCVD 509
+ C P C C ES C+C PG+ G+ C C G C +
Sbjct: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHN 890
Query: 510 GR----CVCNPGFTGEDCG---SRRCPGDCRGHGLCEDGV----CVCDAGYSGEDCST-- 556
+ C C PGF+G DC C+ G C DGV C+C G++G+ C T
Sbjct: 891 TQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 557 -RSCPGGCRGRGQCLD----GRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDGV---- 604
C+ G C D C C+ G+ G C + +C + C G C DG+
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 605 CICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCAT--RMCP-A 654
C+C G+ C I C S+ C G C +G RC C GYTG C T +C +
Sbjct: 1011 CLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRS 1070
Query: 655 DCRGRGRCVQ----GVCLCHVGYGGEDCGQEEPPASACPGGCGPR-----ELCR------ 699
C+ +G CVQ CLC G+ G C + P +C R LC+
Sbjct: 1071 PCKNKGTCVQKKAESQCLCPSGWAGAYC---DVPNVSCDIAASRRGVLVEHLCQHSGVCI 1127
Query: 700 -AGQ---CVCVEGFRGPDCAIQ---TCPGDCRGRGECHD----GSCVCKDGYAGEDCGEE 748
AG C C G+ G C Q C+ C D C C GY G +C E
Sbjct: 1128 NAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE 1187
Query: 749 V 749
V
Sbjct: 1188 V 1188
Score = 246 bits (629), Expect = 3e-64
Identities = 207/752 (27%), Positives = 286/752 (38%), Gaps = 163/752 (21%)
Query: 151 LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTG 210
L + TC C G+ G C T S P G+C D C C G+TG
Sbjct: 85 LGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD-----TYECTCQVGFTG 139
Query: 211 PSCGWPSC--PGDCQGRGRCV----QGVCVCRAGFSGPDC----SQRSCPRGCSQRGRC- 259
C W C C Q C C GF+G C ++ P C G C
Sbjct: 140 KECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL 199
Query: 260 ---EGGRCVCDPGYTGDDCG---MRSCPRGCSQRGRCENG-----RCVCNPGYTGEDC-- 306
+C C G+TG C + P C G C C C PG+ G C
Sbjct: 200 NLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
Query: 307 GVRSCP-RGCSQRGRCKDG----RCVCDPGYTGEDC--GTRSC---PWDCGEGGRCVDGR 356
+ CP C G C DG C C P +TG+ C C P C GG C +
Sbjct: 260 NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRN 319
Query: 357 ----CVCWPGYTGEDCSTR-------TCPRDCRGRGRCEDGECICDTGYSGDDCGVRSC- 404
CVC G++G+DCS +C R C+C G +G C +
Sbjct: 320 GGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDAC 379
Query: 405 -PGDCNQRGRCEDGR------CVCWPGYTGTDCG------SRACPRDCRGRGRCENG--- 448
C++ C+ C C GY G DC + A C G+C N
Sbjct: 380 ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGA 439
Query: 449 -VCVCNAGYSGEDC--GVRSCPGD-CRGRGRC----ESGRCMCWPGYTGRDC--GTRACP 498
C C GY+G C + C D C+ C C+C PG+ G C C
Sbjct: 440 FHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQ 499
Query: 499 GD-CRGRGRCVDG----RCVCNPGFTG-------EDCGSRRC------------------ 528
+ C G+CVD +C+C PGFTG +DC S C
Sbjct: 500 SNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCA 559
Query: 529 ----------------PGDCRGHGLCEDGV----CVCDAGYSGEDCSTR--SC-PGGCRG 565
P C HG C+DG+ C+C+ GY G CS + C C
Sbjct: 560 TGFTGVLCEENIDNCDPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLN 618
Query: 566 RGQCLD----GRCVCEDGYSGEDCGVR--QCPNDCSQHGVCQDGV----CICWEGYVSED 615
G+C+D +C C+ G SG +C + C ++ HG+C DG+ C+C G+ +
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQR 678
Query: 616 CS--IRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM--CPADCRGRGRCVQGV 666
C+ I C SN C C G RC+C G P+C +++ C ++ G C G+
Sbjct: 679 CNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGL 738
Query: 667 ----CLCHVGYGGEDC--GQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAI---Q 717
CLC G+ G +C + E ++ C G L +C C +GF+G +C + +
Sbjct: 739 SGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE 798
Query: 718 TCPGDCRGRGECHDG----SCVCKDGYAGEDC 745
C +G C D +C C Y G++C
Sbjct: 799 CASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Score = 208 bits (530), Expect = 8e-53
Identities = 185/672 (27%), Positives = 241/672 (35%), Gaps = 167/672 (24%)
Query: 222 CQGRGRCVQ-----GVCVCRAGFSGPDCSQRS-CPRG-CSQRGRCEG------GRCVCDP 268
C G CV G C C GF G C R C + C G C C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 269 GYTGDDCGMRSC-----PRGCSQRGRC-----ENGRCVCNPGYTGEDCG------VRSCP 312
G+TG+DC + R C G C + C C G+TG++C C
Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154
Query: 313 RGCSQRGRCKDGRCVCDPGYTGEDCGT--RSC--PWDCGEGGRCVD----GRCVCWPGYT 364
G + C C G+TG+ C T C P C GG C++ +C C G+T
Sbjct: 155 NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
Query: 365 GEDCSTR---TCPRDCRGRGRCEDG-----ECICDTGYSGDDC--GVRSCPGD-CNQRGR 413
G+ C + P C G C EC C G+ G C + CP C G
Sbjct: 215 GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGV 274
Query: 414 CEDG----RCVCWPGYTGTDCGSRA--C---PRDCRGRGRCENGV----CVCNAGYSGED 460
C DG C C P +TG C C P C+ G C N CVC G+SG+D
Sbjct: 275 CVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDD 334
Query: 461 CGVR-------SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCV 513
C SC R S CMC G G C +D C+
Sbjct: 335 CSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCH--------------LDDACI 380
Query: 514 CNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCS------TRSCPGGCRGRG 567
NP G C + G +C C GY G DC+ + C G
Sbjct: 381 SNPCHKGALCDTNPLNGQY---------ICTCPQGYKGADCTEDVDECAMANSNPCEHAG 431
Query: 568 QCL--DG--RCVCEDGYSGEDC--GVRQCPND-CSQHGVCQDGV----CICWEGYVSEDC 616
+C+ DG C C GY+G C + +C +D C C D + C+C G+ C
Sbjct: 432 KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 617 S--IRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM------------------ 651
I C SN C G+C + +CLC PG+TGP C +
Sbjct: 492 ELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP 551
Query: 652 ----------------------CPADCRGRGRCVQGV----CLCHVGYGGEDCGQ--EEP 683
C D G+C G+ C+C+ GY G C +E
Sbjct: 552 NGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDEC 611
Query: 684 PASACPGGCGPRELCRAGQCVCVEGFRGPDCAI--QTCPGDCRGRGECHDG----SCVCK 737
+S C +L QC C G G +C I C + G C DG SCVC
Sbjct: 612 YSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCS 671
Query: 738 DGYAGEDCGEEV 749
G+ G+ C ++
Sbjct: 672 PGFTGQRCNIDI 683
Score = 204 bits (520), Expect = 1e-51
Identities = 209/814 (25%), Positives = 283/814 (34%), Gaps = 163/814 (20%)
Query: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGL---KEQCTGGCCPASAQAGTGQTDVRT 141
C CP G P S+V I GL K C G + + + +
Sbjct: 706 CICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC-LSN 764
Query: 142 LCSLHGVFD--LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVR 199
C G D ++ C+C+ G+ G C D S+P G+C DD +
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE--CASNPCLNQGTCFDDISGY----- 817
Query: 200 GRCVCFPGYTGPSCGW---PSCPGDCQGRGRCVQG------VCVCRAGFSGPDCS---QR 247
C C YTG +C P P C+ C + C+C G+ G C+
Sbjct: 818 -TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDE 876
Query: 248 SCPRGCSQRGRCEGGR----CVCDPGYTGDDC--GMRSC-PRGCSQRGRCENG----RCV 296
+ C G C + C C PG++G DC + C C G C +G C+
Sbjct: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCL 936
Query: 297 CNPGYTGEDC--GVRSC-PRGCSQRGRCKD----GRCVCDPGYTGEDC--GTRSC-PWDC 346
C PG+TG+ C + C C G C D C C G+ G C C C
Sbjct: 937 CLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSC 996
Query: 347 GEGGRCVDG----RCVCWPGYTGEDC---STRTCPRDCRGRGRCEDG----ECICDTGYS 395
GG CVDG C+C G+TG C C G C DG C C GY+
Sbjct: 997 FNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT 1056
Query: 396 GDDCG--VRSCP-GDCNQRGRC----EDGRCVCWPGYTGTDCGSRACPRD---------- 438
G +C V C C +G C + +C+C G+ G C D
Sbjct: 1057 GKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLV 1116
Query: 439 ---CRGRGRCENG----VCVCNAGYSGEDC--GVRSCPGD-CRGRGRCE----SGRCMCW 484
C+ G C N C C GY+G C + C + C+ C RC C
Sbjct: 1117 EHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 485 PGYTGRDCGTRA--CPGD-CRGRGRCVD----GRCVCNPGFTGEDCGSRRCPGDCRGHGL 537
PGY G +C C C+ G C+D +C C PG G L
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL---------------L 1221
Query: 538 CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC- 590
CE+ + C G C GQC+D C C G++GE C + +C
Sbjct: 1222 CEENIDDCARG------------PHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL 1269
Query: 591 PNDCSQHG------VCQDGVCICWEGYVSEDCS--IRTCPS-NCHGRGRCEEGR------ 635
N CS G + D +C+C + C + CP C G C
Sbjct: 1270 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF 1329
Query: 636 -CLCDPGYTGPTCATRMCPADCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACP- 689
C C PG++G C + CR +CV C C DC + +S C
Sbjct: 1330 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDC-ESGCASSPCQH 1385
Query: 690 -GGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCV--CKDGYAGEDCG 746
G C P+ C C F G C + T P C C +DG E C
Sbjct: 1386 GGSCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCLSQYCADKARDGVCDEACN 1444
Query: 747 EEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYE 780
+G L T+ W P+ ++
Sbjct: 1445 SHACQWDGGDCSL----TMENPWANCSSPLPCWD 1474
Score = 173 bits (439), Expect = 3e-42
Identities = 187/688 (27%), Positives = 242/688 (35%), Gaps = 165/688 (23%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPP-----------------SSPPSASG-SCPDD------ 190
TC C PGW G C+ D I PP SG C +D
Sbjct: 858 TCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLA 917
Query: 191 --CNDQGRCVRG----RCVCFPGYTGPSC--GWPSCPGD-CQGRGRCVQGV----CVCRA 237
C + G C+ G C+C PG+TG C C + C+ G C V C C+A
Sbjct: 918 NPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQA 977
Query: 238 GFSGPDCSQR--SCPRG-CSQRGRCEGG----RCVCDPGYTGDDC--GMRSCP-RGCSQR 287
GF G C C C G C G C+C G+TG C + C C
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 288 GRCENG----RCVCNPGYTGEDCG--VRSCPRG-CSQRGRC----KDGRCVCDPGYTGED 336
G C +G RC C GYTG++C V C R C +G C + +C+C G+ G
Sbjct: 1038 GTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAY 1097
Query: 337 CGTRSCPWD-------------CGEGGRCVDGR----CVCWPGYTGEDCSTRT---CPRD 376
C + D C G C++ C C GYTG C +
Sbjct: 1098 CDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNP 1157
Query: 377 CRGRGRCEDG----ECICDTGYSGDDCG--VRSCPGD-CNQRGRCED----GRCVCWPGY 425
C+ C D C C GY G +C V C C G C D +C C PG
Sbjct: 1158 CQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGT 1217
Query: 426 TGTDCGSRA--CPRD--CRGRGRCENGV----CVCNAGYSGEDC--GVRSCPGD-CRGRG 474
G C C R C G+C + + C C G++GE C + C + C G
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEG 1277
Query: 475 RCESGR------CMCWPGYTGRDCGT--RACP-------GDCRGRGRCVDGR-CVCNPGF 518
+ + C+C +TGR C T CP G C DG C C PGF
Sbjct: 1278 SLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGF 1337
Query: 519 TGEDCGSRRCPGDCRGHGLCEDGV----CVCDAGYSGEDCSTRSCPGGCRGRGQCLDGR- 573
+G C S CR C C C S DC + C+ G C R
Sbjct: 1338 SGARCQSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESGCASSPCQHGGSCHPQRQ 1394
Query: 574 -----CVCEDGYSGEDCGVRQCPN-------------DCSQHGVCQDGV---CICWEGYV 612
C C +SG C + P D ++ GVC + W+G
Sbjct: 1395 PPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDG-- 1452
Query: 613 SEDCSIR--------TCPSNC--HGRGRCEE----GRCLCDPGY---TGPTCATRMCPAD 655
DCS+ + P C + +C+E CL D TC AD
Sbjct: 1453 -GDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCAD 1511
Query: 656 CRGRGRCVQGVCLCHVGYGGEDCGQEEP 683
C QG G+ G DC ++P
Sbjct: 1512 HFKDNHCDQGCNSEECGWDGLDCAADQP 1539
Score = 40.4 bits (93), Expect = 0.038
Identities = 59/246 (23%), Positives = 78/246 (31%), Gaps = 52/246 (21%)
Query: 78 NLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQC----TGGCC----PAS 129
N+P C CPPG S ++ R KG EQC +G C P
Sbjct: 1324 NMPDGFICRCPPGFSGARCQSSCGQVKCR--------KG--EQCVHTASGPRCFCPSPRD 1373
Query: 130 AQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSA--SGSC 187
++G + + S H +C C P + G C T PPS+PP+ S C
Sbjct: 1374 CESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT---APPSTPPATCLSQYC 1430
Query: 188 PDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQR 247
D D VC +C W GDC C + D
Sbjct: 1431 ADKARDG--------VCDEACNSHACQWDG--GDCS--LTMENPWANCSSPLPCWDYINN 1478
Query: 248 SCPRGCS------QRGRCEGGRCVCD-PGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPG 300
C C+ C+G C Y D C +GC+ C G
Sbjct: 1479 QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSE-EC---------G 1528
Query: 301 YTGEDC 306
+ G DC
Sbjct: 1529 WDGLDC 1534
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 251 bits (642), Expect = 8e-66
Identities = 214/739 (28%), Positives = 275/739 (37%), Gaps = 164/739 (22%)
Query: 151 LSRCTCSCEPGWGGPTCSDPTDAE----------------IPPSSPPSASGSCPDDCNDQ 194
L + TC C PG+ G TC P + P P S S P
Sbjct: 46 LGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFL--- 102
Query: 195 GRCVRGRCVCFPGYTGPSCGW----PSCPGDCQGRGRC-VQG----VCVCRAGFSGPDCS 245
C C PG+TG C P P C RGRC +Q C C G++G C
Sbjct: 103 -------CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQ 155
Query: 246 QRSCPRGCSQRGRCEGG---------RCVCDPGYTGDDC---------GMRSCPRGCSQR 287
R CS GG +C C PG+ G C CP+G S
Sbjct: 156 LRDF---CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCH 212
Query: 288 GRCENGRCVCNPGYTGEDCGVRS--C-PRGCSQRGRC-----KDGR---CVCDPGYTGED 336
+ +C+C G G C +R+ C PRGCS G C KD C+C PG+ G D
Sbjct: 213 NTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPD 272
Query: 337 CGTR--SC-PWDCGEGGRCVDG----RCVCWPGYTGEDCS--TRTC----PRDCRGRGRC 383
C +C C GG C DG C+C +TG DCS C P CR G C
Sbjct: 273 CEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTC 332
Query: 384 EDG----ECICDTGYSG-------DDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDC-- 430
++ C+C +G+ G DDC +C R C+C PG TG C
Sbjct: 333 QNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
Query: 431 GSRACPRDCRGRGRCENG------VCVCNAGYSGEDCG--------VRSCPGDCRGRGRC 476
+ C G +C +C+C GYSG C + P C G C
Sbjct: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
Query: 477 ----ESGRCMCWPGYTGRDC---GTRACPGDCRGRGRCVD----GRCVCNPGFTGE---- 521
S C+C PGYTG C C C+D C+C PG G+
Sbjct: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV 512
Query: 522 ---DCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC-----STRSCPGGCRGRGQCLDG- 572
+C S C H L C+C G+SG C RS P C GQC D
Sbjct: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQP 570
Query: 573 ---RCVCEDGYSGEDC--GVRQCPND-CSQHGVCQD----GVCICWEGYVSEDCSIRTC- 621
C C G+ G C V +C +D C C D C+C G+ + C + C
Sbjct: 571 GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCA 630
Query: 622 PSNCHGRGRC----EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGED 677
P+ C + C ++ CLC G P CA C G C + C+C VG+ G +
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDG--SPGCAPPEDNCTCH-HGHCQRSSCVCDVGWTGPE 687
Query: 678 CGQEEPPASACP----GGCGPRELCRAGQCVCVEGFRGPDCA--IQTC-PGDCRGRGECH 730
C E + P G C P+ C C G+ GP C+ + C G C G C+
Sbjct: 688 CEAELGGCISAPCAHGGTCYPQP--SGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 731 DGS----CVCKDGYAGEDC 745
C C + G C
Sbjct: 746 PSPGGYYCTCPPSHTGPQC 764
Score = 219 bits (558), Expect = 5e-56
Identities = 221/832 (26%), Positives = 293/832 (35%), Gaps = 183/832 (21%)
Query: 81 PSTGCGCPPGTEPPVLASEVQ-------------ALRVRLEILEELV----KGLKEQCTG 123
P C CPPG E +V + L + L +G + +
Sbjct: 176 PQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRA 235
Query: 124 GCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSA 183
G CP + G C L D + C C PG+ GP C E+ P + S
Sbjct: 236 GPCPPRGCSNGG------TCQLMPEKDSTFHLCLCPPGFIGPDC------EVNPDNCVS- 282
Query: 184 SGSCPDDCNDQGRCVRG----RCVCFPGYTGPSCG--WPSC----PGDCQGRGRCVQGV- 232
C + G C G C+C +TG C C P C+ G C
Sbjct: 283 -----HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
Query: 233 ---CVCRAGFSG-------PDCSQRSCPRGCSQRGRCEGGRCVCDPGYTG------DDCG 276
CVC +G+ G DC +C G + R C+C PG TG D C
Sbjct: 338 SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCL 397
Query: 277 MRSC--PRGCSQRGRCENGRCVCNPGYTGEDCG--------VRSCPRGCSQRGRCKDG-- 324
+ C CS + C+C PGY+G C + P C G C +
Sbjct: 398 SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPG 457
Query: 325 --RCVCDPGYTGEDC---GTRSCPWDCGEGGRCVD----GRCVCWPGYTGEDCSTRT--- 372
C+C PGYTG C C G C+D C+C PG G+ C T
Sbjct: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517
Query: 373 CPRDCRGRGRCED----GECICDTGYSGDDC-----GVRSCPGDCNQRGRCEDG----RC 419
C C D +CIC G+SG C RS P C G+C+D C
Sbjct: 518 ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHC 575
Query: 420 VCWPGYTG-------TDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSC-PGDCR 471
C PG+ G +C S CP C+C +G++G+ C V C P C+
Sbjct: 576 KCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQ 635
Query: 472 GRGRC----ESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRR 527
+ C + C+C G G C C G C CVC+ G+TG +C +
Sbjct: 636 PKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCH-HGHCQRSSCVCDVGWTGPECEAEL 692
Query: 528 ---CPGDCRGHGLC----EDGVCVCDAGYSGEDCS---TRSCPGGCRGRGQCLDG----R 573
C G C C C GY+G CS T G C G C
Sbjct: 693 GGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752
Query: 574 CVCEDGYSGEDC--GVRQCPN-DCSQHGVCQDG----VCICWEGYVSEDCSIRTCP---- 622
C C ++G C C + C G C + C+C G+ C + P
Sbjct: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
Query: 623 SNCHGRGRCEEG----RCLCDPGYTGPTCATRM---CPADCRGRGRCVQG----VCLCHV 671
S C R C++ RCLC GYTG +C T M C C+Q CLC
Sbjct: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
Query: 672 GYGGEDCGQEEPPASAC-----PGGCGPRELCRAGQ----------CVCVEGFRGPDCAI 716
G+ G C P S+C G LC G C C GF+G C
Sbjct: 873 GWTGPLCNL---PLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD 929
Query: 717 QTCPGDCRGRGECHDGS----------CVCKDGYAGEDCGEEVPTIEGMRMH 758
P + R C +G+ C C GY G++C +E+ + H
Sbjct: 930 HVNPCESR---PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCH 978
Score = 218 bits (556), Expect = 8e-56
Identities = 217/825 (26%), Positives = 273/825 (33%), Gaps = 210/825 (25%)
Query: 82 STGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRT 141
S C CPPG L+ L++ C C AQ T T
Sbjct: 376 SFSCLCPPGRTG-------------------LLCHLEDMCLSQPCHGDAQCSTNPLTGST 416
Query: 142 LCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG- 200
LC C+PG+ GPTC D + PS C G C+
Sbjct: 417 LCL-------------CQPGYSGPTCHQDLDECLMAQQGPSP-------CEHGGSCLNTP 456
Query: 201 ---RCVCFPGYTGPSC--------GWPSCPGD---------------------------- 221
C+C PGYTG C P PG
Sbjct: 457 GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE 516
Query: 222 -----CQGRGRC---VQGV-CVCRAGFSGPDCSQ-----RSCPRGCSQRGRCEGG----R 263
C C + G C+C GFSG C + RS P C+ G+C+
Sbjct: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFH 574
Query: 264 CVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGC 315
C C PG+ G D+C CP G S C+C G+TG+ C V C P C
Sbjct: 575 CKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLC 634
Query: 316 SQRGRCKDGR----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTR 371
+ CKD + C+C G G C C G C CVC G+TG +C
Sbjct: 635 QPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTCHHG-HCQRSSCVCDVGWTGPECEAE 691
Query: 372 T---CPRDCRGRGRC----EDGECICDTGYSGDDCG--VRSC-PGDCNQRGRCEDGR--- 418
C G C C C TGY+G C + +C G C G C
Sbjct: 692 LGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 419 -CVCWPGYTGTDCGSRA---CPRDCRGRGRCENGV----CVCNAGYSGEDCGVRSCPG-- 468
C C P +TG C + C G C N C+C G+ G C + P
Sbjct: 752 YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 469 --DCRGRGRCESG----RCMCWPGYTGRDCGT-------RACPGDCRGRGRCVDGRCVCN 515
CR R C+ RC+C GYTG C T + CP + C+C
Sbjct: 812 DSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCL 871
Query: 516 PGFTGEDCGSRRCPGD-------------CRGHGLCEDG----VCVCDAGYSGE------ 552
G+TG C C GLC D C C G+ G
Sbjct: 872 QGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHV 931
Query: 553 -DCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCG--VRQCPND-CSQHGVCQDGV---- 604
C +R C G Q C C GY G++C + C + C HG C
Sbjct: 932 NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991
Query: 605 CICWEGYVSEDCS--IRTCPSN-CH--GRGRCEEGR----CLCDPGYTGPTCATRMCPAD 655
C C G+V C + C CH G C C C PG+TG C + P
Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCH 1051
Query: 656 ---CRGRGRC-------VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG---- 701
C G C + +C C G+ G C P C LC
Sbjct: 1052 SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF--HHCHHGGLCLPSPKPG 1109
Query: 702 ---QCVCVEGFRGPDCAIQTCPGDCRGRGEC-HDGSCVCKDGYAG 742
+C C+ G+ GPDC P C C ++GSC G G
Sbjct: 1110 FPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGG 1154
Score = 185 bits (469), Expect = 9e-46
Identities = 206/759 (27%), Positives = 252/759 (33%), Gaps = 196/759 (25%)
Query: 80 PPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDV 139
P + C C PG E P +EV ++C CP A
Sbjct: 570 PGAFHCKCLPGFEGPRCQTEV------------------DECLSDPCPVGASC------- 604
Query: 140 RTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDA-------EIPPSSPPSASGSCPD--- 189
L G F C C G+ G C P A +I A+ CPD
Sbjct: 605 ---LDLPGAF-----FCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSP 656
Query: 190 -------DCN-DQGRCVRGRCVCFPGYTGPSC-----GWPSCPGDCQGRGRCVQGV---- 232
+C G C R CVC G+TGP C G S P C G C
Sbjct: 657 GCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAP--CAHGGTCYPQPSGYN 714
Query: 233 CVCRAGFSGPDCSQR--SCPRG-CSQRGRCE----GGRCVCDPGYTGDDCGMRS---CPR 282
C C G++GP CS+ +C G C G C G C C P +TG C +
Sbjct: 715 CTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA 774
Query: 283 GCSQRGRCENG----RCVCNPGYTGEDCGVRSCPR----GCSQRGRCKDG----RCVCDP 330
C G C N C+C G+ G C + P C R C+D RC+C
Sbjct: 775 PCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPT 834
Query: 331 GYTGEDCGTRS---CPWDCGEGGRCVDG----RCVCWPGYTGEDCST--RTCPRD----- 376
GYTG C T C C+ C+C G+TG C+ +C +
Sbjct: 835 GYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 377 ------CRGRGRCEDGE----CICDTGYSG-------DDCGVRSCPGDCNQRGRCEDGRC 419
C G C D C C G+ G + C R C + C
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC 954
Query: 420 VCWPGYTGTDCGSR--ACP-RDCRGRGRCENGV----CVCNAGYSGEDC--GVRSC---P 467
C PGY G +C AC + C G C C C G+ G C V C P
Sbjct: 955 QCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQP 1014
Query: 468 GDCRGRGRCESGR----CMCWPGYTGRDCGTRACP---------GDCRGR-GRCVDGRCV 513
G C S C C PG+TG+ C P G C G + C
Sbjct: 1015 CHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICH 1074
Query: 514 CNPGFTGEDCGSRRCPG----DCRGHGLCEDGV-------CVCDAGYSGEDCSTRSCPGG 562
C GF G C S R P C GLC C C +GY G DC T P G
Sbjct: 1075 CPKGFEGPTC-SHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG 1133
Query: 563 CRGRGQCLDG--------------RCVCEDGYSGEDC---GVRQCPNDCSQHGVCQDGVC 605
C CL RC C G C G + C S G C G
Sbjct: 1134 CGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGR-SGDGACDAGCS 1192
Query: 606 ICWEGYVSEDCSI------RTCPSN-----------CHGRGRCEEGRCLCDPGY---TGP 645
+ DCS+ + CPS+ CH +C+ CL D GY T P
Sbjct: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCH--PQCDSEECLFD-GYDCETPP 1249
Query: 646 TC--ATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEE 682
C A D G C +G G+ G DC E+
Sbjct: 1250 ACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPED 1288
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 235 bits (599), Expect = 8e-61
Identities = 113/292 (38%), Positives = 145/292 (49%), Gaps = 25/292 (8%)
Query: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
V+ CP +C+ G C G C C+PG+ G DC ACP C G G+ G C C +G+ G +
Sbjct: 573 VQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAE 632
Query: 461 CGV---RSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRAC-PGDCRGRGRCVDGRCVCNP 516
C V + C G G C G C+C GY G C C C G CV+G C+C+P
Sbjct: 633 CDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSP 692
Query: 517 GFTGEDCGSRR--CPGDCRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG 572
G+ G +C R CP C GHG L + G+C CD + G DCS C C G C+ G
Sbjct: 693 GWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGG 752
Query: 573 RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCE 632
C CE+G++G C R C C +HG C+DG C C EG+ E C+I CP C+G GRC
Sbjct: 753 ACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCT 812
Query: 633 EG----RCLCDPGYTGPTCATRM---CP----------ADCRGRGRCVQGVC 667
G +C+C G+ GP C M C DC C+Q C
Sbjct: 813 LGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSAC 864
Score = 219 bits (558), Expect = 5e-56
Identities = 111/291 (38%), Positives = 141/291 (48%), Gaps = 24/291 (8%)
Query: 463 VRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGED 522
V+ CP +C G G C SG C C+PG+ G DC ACP C G G+ G C C G+ G +
Sbjct: 573 VQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAE 632
Query: 523 CG---SRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC-PGGCRGRGQCLDGRCVCED 578
C ++ C GHG C DG CVC AGY GE C C C G C++G C+C
Sbjct: 633 CDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSP 692
Query: 579 GYSGEDCGVR--QCPNDCSQHGVC--QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG 634
G+ G +C + QCP+ CS HG G+C C ++ DCS+ C +C G C G
Sbjct: 693 GWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGG 752
Query: 635 RCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGP 694
C C+ G+TG C R+C C G C G C C G+ GE C CP C
Sbjct: 753 ACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHC-----TIDGCPDLCNG 807
Query: 695 RELCRAG----QCVCVEGFRGPDC--AIQTCPGDCR-----GRGECHDGSC 734
C G QCVC G+RGP C A++T D + G +C D C
Sbjct: 808 NGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
Score = 218 bits (556), Expect = 8e-56
Identities = 103/267 (38%), Positives = 128/267 (47%), Gaps = 17/267 (6%)
Query: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
CP +C G G CV G C C PGF G DC CP C G+G G C C +G+ G +C
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 557 ---RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612
+ C G G C+DG CVC GY GE C C + CS HGVC +G C+C G+
Sbjct: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
Query: 613 SEDCSIRT--CPSNCHGRGRC--EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668
+C + CP C G G + G C CDP + GP C+ +C DC G C+ G C
Sbjct: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
Query: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
C G+ G C Q C C C+ G+C C EG+ G C I CP C G G
Sbjct: 756 CEEGWTGAACDQR-----VCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGR 810
Query: 729 CHDGS----CVCKDGYAGEDCGEEVPT 751
C G CVC+ G+ G C + T
Sbjct: 811 CTLGQNSWQCVCQTGWRGPGCNVAMET 837
Score = 218 bits (555), Expect = 1e-55
Identities = 101/256 (39%), Positives = 128/256 (50%), Gaps = 12/256 (4%)
Query: 187 CPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCS- 245
CP +C+ G CV G C CFPG+ G C +CP C G G+ +G C C +G+ G +C
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 246 --QRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSC-PRGCSQRGRCENGRCVCNPGYT 302
+ C G C G CVC GY G+ C C CS G C NG C+C+PG+
Sbjct: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
Query: 303 GEDCGVR--SCPRGCSQRGRC--KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCV 358
G +C + CP CS G G C CDP + G DC C DCG G C+ G C
Sbjct: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
Query: 359 CWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDG- 417
C G+TG C R C C G C+DG+C C G++G+ C + CP CN GRC G
Sbjct: 756 CEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQ 815
Query: 418 ---RCVCWPGYTGTDC 430
+CVC G+ G C
Sbjct: 816 NSWQCVCQTGWRGPGC 831
Score = 213 bits (543), Expect = 2e-54
Identities = 102/260 (39%), Positives = 124/260 (47%), Gaps = 12/260 (4%)
Query: 245 SQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGE 304
S + CPR C G C G C C PG+ G DC +CP CS G+ G C C G+ G
Sbjct: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
Query: 305 DCGV---RSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSC-PWDCGEGGRCVDGRCVCW 360
+C V + C G C DG CVC GY GE C C C G CV+G C+C
Sbjct: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
Query: 361 PGYTGEDCSTRT--CPRDCRGRGRC--EDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
PG+ G +C CP C G G + G C CD + G DC V C DC G C
Sbjct: 692 PGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG 751
Query: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476
G C C G+TG C R C C G C++G C C G++GE C + CP C G GRC
Sbjct: 752 GACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRC 811
Query: 477 ESG----RCMCWPGYTGRDC 492
G +C+C G+ G C
Sbjct: 812 TLGQNSWQCVCQTGWRGPGC 831
Score = 192 bits (489), Expect = 5e-48
Identities = 109/313 (34%), Positives = 137/313 (43%), Gaps = 38/313 (12%)
Query: 146 HGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCF 205
HG + C C PG+ G C A +CP C+ G+ +G C C+
Sbjct: 581 HGNGECVSGVCHCFPGFLGADC---------------AKAACPVLCSGNGQYSKGTCQCY 625
Query: 206 PGYTGPSCGWP---SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSC-PRGCSQRGRCEG 261
G+ G C P C G G C+ G CVC AG+ G C + C CS G C
Sbjct: 626 SGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVN 685
Query: 262 GRCVCDPGYTGDDCGMR--SCPRGCSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQ 317
G C+C PG+ G +C + CP CS G + G C C+P + G DC V C C
Sbjct: 686 GECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGT 745
Query: 318 RGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDC 377
G C G C C+ G+TG C R C C E G C DG+C C G+ GE C+ CP C
Sbjct: 746 HGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLC 805
Query: 378 RGRGRCEDG----ECICDTGYSGDDCGV---RSCPGDCNQRGRCEDGRCVCWPGYTGTDC 430
G GRC G +C+C TG+ G C V SC + + G DG C C
Sbjct: 806 NGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG---DGLVDC---LDPDCC 859
Query: 431 GSRACPRD--CRG 441
AC CRG
Sbjct: 860 LQSACQNSLLCRG 872
Score = 179 bits (454), Expect = 5e-44
Identities = 92/235 (39%), Positives = 112/235 (47%), Gaps = 18/235 (7%)
Query: 528 CPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGV 587
CP +C G+G C GVC C G+ G DC+ +CP C G GQ G C C G+ G +C V
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 588 --RQCPN-DCSQHGVCQDGVCICWEGYVSEDCSIRTC-PSNCHGRGRCEEGRCLCDPGYT 643
QC + C HG C DG C+C GY E C C C G C G CLC PG+
Sbjct: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
Query: 644 GPTC--ATRMCPADCRGRGRCVQ--GVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR 699
G C A CP C G G + G+C C + G DC E C CG +C
Sbjct: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVE-----VCSVDCGTHGVCI 750
Query: 700 AGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEG 754
G C C EG+ G C + C C G C DG C C++G+ GE C TI+G
Sbjct: 751 GGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHC-----TIDG 800
Score = 174 bits (442), Expect = 1e-42
Identities = 100/288 (34%), Positives = 124/288 (43%), Gaps = 33/288 (11%)
Query: 120 QCTGGCC---PASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIP 176
+C G C P A + LCS +G + TC C GW G C P + I
Sbjct: 585 ECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKG--TCQCYSGWKGAECDVPMNQCID 642
Query: 177 PSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSC-PGDCQGRGRCVQGVCVC 235
PS C G C+ G CVC GY G C C C G CV G C+C
Sbjct: 643 PS------------CGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLC 690
Query: 236 RAGFSGPDC--SQRSCPRGCSQRGRC--EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE 291
G+ G +C ++ CP CS G + G C CDP + G DC + C C G C
Sbjct: 691 SPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCI 750
Query: 292 NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGR 351
G C C G+TG C R C C + G CKDG+C C G+ GE C CP C GR
Sbjct: 751 GGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGR 810
Query: 352 CVDG----RCVCWPGYTGEDCST---RTCP--RDCRGRG--RCEDGEC 388
C G +CVC G+ G C+ +C +D G G C D +C
Sbjct: 811 CTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
Score = 152 bits (383), Expect = 9e-36
Identities = 72/201 (35%), Positives = 96/201 (47%), Gaps = 9/201 (4%)
Query: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSE 614
S + CP C G G+C+ G C C G+ G DC CP CS +G G C C+ G+
Sbjct: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
Query: 615 DCSI---RTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVCLCH 670
+C + + +C G G C +G C+C GY G C C C G CV G CLC
Sbjct: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
Query: 671 VGYGGEDCGQEEPPASACPGGCGPR--ELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
G+GG +C E CP C L G C C + GPDC+++ C DC G
Sbjct: 692 PGWGGLNC---ELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
Query: 729 CHDGSCVCKDGYAGEDCGEEV 749
C G+C C++G+ G C + V
Sbjct: 749 CIGGACRCEEGWTGAACDQRV 769
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 234 bits (596), Expect = 2e-60
Identities = 105/256 (41%), Positives = 138/256 (53%), Gaps = 12/256 (4%)
Query: 187 CPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDC-- 244
CP +C+ G CV G C CFPG+ GP C +CP C G G+ +G C+C +G+ G +C
Sbjct: 518 CPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDV 577
Query: 245 -SQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSC-PRGCSQRGRCENGRCVCNPGYT 302
+ + C RG C G C C+ GY G+ C C GCS G C +G C C+PG+
Sbjct: 578 PTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWG 637
Query: 303 GEDCGVRS--CPRGCSQRGRC--KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCV 358
G +C + CP CS G + G C CDP +TG DC C DCG G C+ G C
Sbjct: 638 GSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCR 697
Query: 359 CWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRC---E 415
C G+TG C+ R C C G C+DG+C C G++G+ C + CPG CN GRC +
Sbjct: 698 CEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQ 757
Query: 416 DG-RCVCWPGYTGTDC 430
+G CVC PG+ G C
Sbjct: 758 NGWHCVCQPGWRGAGC 773
Score = 231 bits (588), Expect = 2e-59
Identities = 113/293 (38%), Positives = 144/293 (49%), Gaps = 27/293 (9%)
Query: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
V CP +C+ G C G C C+PG+ G DC ACP C G G+ G C+C +G+ G +
Sbjct: 515 VVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTE 574
Query: 461 CGV---RSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRAC--PGDCRGRGRCVDGRCVCN 515
C V + C GRG C G C C GY G C C PG C G C+ G C C+
Sbjct: 575 CDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPG-CSNHGVCIHGECHCS 633
Query: 516 PGFTGEDCG--SRRCPGDCRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571
PG+ G +C CP C GHG L E G C CD ++G DCS C C G C+
Sbjct: 634 PGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG 693
Query: 572 GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631
G C CE+G++G C R C C++HG C+DG C C +G+ E C+I CP C+ GRC
Sbjct: 694 GTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRC 753
Query: 632 ---EEG-RCLCDPGYTGPTCATRM---CP----------ADCRGRGRCVQGVC 667
+ G C+C PG+ G C M C DC C+Q C
Sbjct: 754 TLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDCCLQSSC 806
Score = 226 bits (575), Expect = 5e-58
Identities = 118/314 (37%), Positives = 149/314 (47%), Gaps = 28/314 (8%)
Query: 342 CPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGV 401
CP +C G CV G C C+PG+ G DCS CP C G G+ G C+C +G+ G +C V
Sbjct: 518 CPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDV 577
Query: 402 ---RSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRAC-PRDCRGRGRCENGVCVCNAGYS 457
+ C RG C G C C GY G C C C G C +G C C+ G+
Sbjct: 578 PTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWG 637
Query: 458 GEDCGVRS--CPGDCRGRGRC--ESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCV 513
G +C + CP C G G ESG C C P +TG DC C DC G C+ G C
Sbjct: 638 GSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCR 697
Query: 514 CNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQC-LD- 571
C G+TG C R C C HG C+DG C C G++GE C+ CPG C G+C LD
Sbjct: 698 CEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQ 757
Query: 572 --GRCVCEDGYSGEDCGVRQ---CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCH 626
CVC+ G+ G C V C + G DG+ C + DC ++ S+C
Sbjct: 758 NGWHCVCQPGWRGAGCDVAMETLCTDSKDNEG---DGLIDC----MDPDCCLQ---SSCQ 807
Query: 627 GRGRCEEGRCLCDP 640
+ C R L DP
Sbjct: 808 NQPYC---RGLPDP 818
Score = 221 bits (564), Expect = 9e-57
Identities = 100/257 (38%), Positives = 126/257 (49%), Gaps = 14/257 (5%)
Query: 435 CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCG- 493
CPR+C G G C +G C C G+ G DC +CP C G G+ GRC+C+ G+ G +C
Sbjct: 518 CPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDV 577
Query: 494 --TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRC--PGDCRGHGLCEDGVCVCDAGY 549
T+ C GRG C+ G C CN G+ GE C C PG C HG+C G C C G+
Sbjct: 578 PTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPG-CSNHGVCIHGECHCSPGW 636
Query: 550 SGEDCSTRS--CPGGCRGRGQCLD--GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVC 605
G +C CP C G G L G C C+ ++G DC C DC HGVC G C
Sbjct: 637 GGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTC 696
Query: 606 ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 665
C EG+ C+ R C C G C++G+C C G+ G C CP C GRC
Sbjct: 697 RCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLD 756
Query: 666 V----CLCHVGYGGEDC 678
C+C G+ G C
Sbjct: 757 QNGWHCVCQPGWRGAGC 773
Score = 219 bits (557), Expect = 6e-56
Identities = 112/309 (36%), Positives = 144/309 (46%), Gaps = 29/309 (9%)
Query: 308 VRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGED 367
V CPR C G C G C C PG+ G DC +CP C G+ GRC+C+ G+ G +
Sbjct: 515 VVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTE 574
Query: 368 C---STRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSC--PGDCNQRGRCEDGRCVCW 422
C +T+ C GRG C G C C++GY G+ C C PG C+ G C G C C
Sbjct: 575 CDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPG-CSNHGVCIHGECHCS 633
Query: 423 PGYTGTDCG--SRACPRDCRGRGRC--ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCES 478
PG+ G++C CP C G G E+G C C+ ++G DC C DC G C
Sbjct: 634 PGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG 693
Query: 479 GRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLC 538
G C C G+TG C RAC C G C DG+C C+ G+ GE C CPG C +G C
Sbjct: 694 GTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRC 753
Query: 539 ---EDG-VCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPN-D 593
++G CVC G+ G C +C D E G+ C + D
Sbjct: 754 TLDQNGWHCVCQPGWRGAGCDVAM--------------ETLCTDSKDNEGDGLIDCMDPD 799
Query: 594 CSQHGVCQD 602
C CQ+
Sbjct: 800 CCLQSSCQN 808
Score = 216 bits (550), Expect = 4e-55
Identities = 110/291 (37%), Positives = 139/291 (47%), Gaps = 24/291 (8%)
Query: 463 VRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGED 522
V CP +C G G C SG C C+PG+ G DC ACP C G G+ GRC+C G+ G +
Sbjct: 515 VVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTE 574
Query: 523 CG--SRRC-PGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC-PGGCRGRGQCLDGRCVCED 578
C + +C C G G+C G C C++GY GE C C GC G C+ G C C
Sbjct: 575 CDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSP 634
Query: 579 GYSGEDCGVRQ--CPNDCSQHGVC--QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG 634
G+ G +C + + CP+ CS HG + G C C + DCS C +C G C G
Sbjct: 635 GWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGG 694
Query: 635 RCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGP 694
C C+ G+TGP C R C C G C G C C G+ GE C E CPG C
Sbjct: 695 TCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIE-----GCPGLCNS 749
Query: 695 RELCRAGQ----CVCVEGFRGPDC--AIQTCPGDCR-----GRGECHDGSC 734
C Q CVC G+RG C A++T D + G +C D C
Sbjct: 750 NGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDC 800
Score = 203 bits (516), Expect = 3e-51
Identities = 100/268 (37%), Positives = 129/268 (48%), Gaps = 27/268 (10%)
Query: 146 HGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCF 205
HG + TC C PG+ GP CS +CP C+ G+ +GRC+CF
Sbjct: 523 HGNGECVSGTCHCFPGFLGPDCS---------------RAACPVLCSGNGQYSKGRCLCF 567
Query: 206 PGYTGPSCGWPS---CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSC-PRGCSQRGRCEG 261
G+ G C P+ C GRG C+ G C C +G+ G C + C GCS G C
Sbjct: 568 SGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIH 627
Query: 262 GRCVCDPGYTGDDCGM--RSCPRGCSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQ 317
G C C PG+ G +C + CP CS G E+G C C+P +TG DC C C
Sbjct: 628 GECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGS 687
Query: 318 RGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDC 377
G C G C C+ G+TG C R+C C E G C DG+C C G+ GE C+ CP C
Sbjct: 688 HGVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLC 747
Query: 378 RGRGRC---EDG-ECICDTGYSGDDCGV 401
GRC ++G C+C G+ G C V
Sbjct: 748 NSNGRCTLDQNGWHCVCQPGWRGAGCDV 775
Score = 185 bits (470), Expect = 7e-46
Identities = 102/289 (35%), Positives = 122/289 (42%), Gaps = 35/289 (12%)
Query: 120 QCTGGCC---PASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIP 176
+C G C P + LCS +G + RC C GW G C PT I
Sbjct: 527 ECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCF--SGWKGTECDVPTTQCID 584
Query: 177 PSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSC--PGDCQGRGRCVQGVCV 234
P C +G C+ G C C GY G SC C PG C G C+ G C
Sbjct: 585 P------------QCGGRGICIMGSCACNSGYKGESCEEADCIDPG-CSNHGVCIHGECH 631
Query: 235 CRAGFSGPDCS--QRSCPRGCSQRGRC--EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRC 290
C G+ G +C + CP CS G E G C CDP +TG DC C C G C
Sbjct: 632 CSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVC 691
Query: 291 ENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGG 350
G C C G+TG C R+C C++ G CKDG+C C G+ GE C CP C G
Sbjct: 692 MGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNG 751
Query: 351 RCV----DGRCVCWPGYTGEDCSTR-----TCPRDCRGRG--RCEDGEC 388
RC CVC PG+ G C T +D G G C D +C
Sbjct: 752 RCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDC 800
Score = 182 bits (461), Expect = 8e-45
Identities = 93/235 (39%), Positives = 109/235 (46%), Gaps = 18/235 (7%)
Query: 528 CPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGV 587
CP +C G+G C G C C G+ G DCS +CP C G GQ GRC+C G+ G +C V
Sbjct: 518 CPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDV 577
Query: 588 --RQCPN-DCSQHGVCQDGVCICWEGYVSEDCSIRTC-PSNCHGRGRCEEGRCLCDPGYT 643
QC + C G+C G C C GY E C C C G C G C C PG+
Sbjct: 578 PTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWG 637
Query: 644 GPTCAT--RMCPADCRGRGRCVQ--GVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR 699
G C MCP C G G +Q G C C + G DC E C CG +C
Sbjct: 638 GSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNE-----ICSVDCGSHGVCM 692
Query: 700 AGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEG 754
G C C EG+ GP C + C C G C DG C C G+ GE C TIEG
Sbjct: 693 GGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHC-----TIEG 742
Score = 151 bits (381), Expect = 2e-35
Identities = 71/199 (35%), Positives = 95/199 (47%), Gaps = 9/199 (4%)
Query: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSE 614
S CP C G G+C+ G C C G+ G DC CP CS +G G C+C+ G+
Sbjct: 514 SVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGT 573
Query: 615 DCSIRT---CPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVCLCH 670
+C + T C GRG C G C C+ GY G +C C C G C+ G C C
Sbjct: 574 ECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCS 633
Query: 671 VGYGGEDCGQEEPPASACPGGCGPR--ELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
G+GG +C E + CP C L +G C C + GPDC+ + C DC G
Sbjct: 634 PGWGGSNC---EILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGV 690
Query: 729 CHDGSCVCKDGYAGEDCGE 747
C G+C C++G+ G C +
Sbjct: 691 CMGGTCRCEEGWTGPACNQ 709
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 233 bits (594), Expect = 3e-60
Identities = 189/650 (29%), Positives = 256/650 (39%), Gaps = 110/650 (16%)
Query: 200 GRCVCFPGYTGPSCGWPSCPGDCQGR-GRC-VQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
G C G+ GP C C C + G C + G C C+ G+ G C + GC
Sbjct: 216 GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGI 275
Query: 258 RCEGGRCVCDPGYTGDDCG--MRSCP--RGCSQRGRCENG-----RCVCNPGYTGEDCGV 308
E +C+C+ + G C + C + C G C N +C C GY+G +C +
Sbjct: 276 CNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI 335
Query: 309 --RSCPRG-CSQRGRCKDG----RCVCDPGYTGEDCGTR---SCPWDCGEGGRCVD---- 354
+C C RG CK+ C C PG+TG C T P +C GG C D
Sbjct: 336 AEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNG 395
Query: 355 GRCVCWPGYTGE-------DCSTRTCPRDCRGRGRCEDGECICDTGYSGDDC--GVRSCP 405
+CVC P +TG+ +C + C + C C G+ G +C + C
Sbjct: 396 FKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL 455
Query: 406 GDCNQRGRCED----GRCVCWPGYTGTDCG---SRACPRDCRGRGRCENGV----CVCNA 454
G C C D RC+C PGY G C C G C+N + C+C
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515
Query: 455 GYSGEDC--GVRSC-PGDCRGRGRCESGR----CMCWPGYTGRDCGTRACPGDCRGRGRC 507
G+SG C + C P C+ +C + C C Y G++C CR
Sbjct: 516 GFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSH--LKDHCRTTPCE 573
Query: 508 VDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDG-----VCVCDAGYSGEDC--STRSC 559
V C G R + C HG C+ C C+ G++G C + C
Sbjct: 574 VIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 560 PGG-CRGRGQCLDG----RCVCEDGYSGEDCGVRQCPNDCSQH-----GVCQDGV----C 605
CR G C+DG +C+C DG+ G C NDCSQ+ G C+D V C
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI--NDCSQNPCHNGGTCRDLVNDFYC 691
Query: 606 ICWEGYVSEDCSIRTCP---SNCHGRGRC-EEG---RCLCDPGYTGPTCA----TRMCPA 654
C G+ + C R + C+ G C +EG +C+C G+ G TC + P
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPN 751
Query: 655 DCRGRGRCVQG----VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG----QCVCV 706
C G CV C+C G+ G C Q S P C C G +C C
Sbjct: 752 PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHP--CYNSGTCVDGDNWYRCECA 809
Query: 707 EGFRGPDCAI-----QTCPGDCRGRGECHDG----SCVCKDGYAGEDCGE 747
GF GPDC I Q+ P C C D CVC G++G C E
Sbjct: 810 PGFAGPDCRININECQSSP--CAFGATCVDEINGYRCVCPPGHSGAKCQE 857
Score = 226 bits (577), Expect = 3e-58
Identities = 196/718 (27%), Positives = 269/718 (37%), Gaps = 157/718 (21%)
Query: 157 SCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQ--------------GRCVRG-- 200
+C GW GP C+ + SP S P DC Q CV G
Sbjct: 219 TCMEGWMGPECNRAICRQ--GCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGIC 276
Query: 201 ----RCVCFPGYTGPSC----GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDC--S 245
+C+C + G C + C G C + C C G+SGP+C +
Sbjct: 277 NEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIA 336
Query: 246 QRSC-PRGCSQRGRCE----GGRCVCDPGYTGDDCGMR---SCPRGCSQRGRCE---NG- 293
+ +C C RG C+ G C C PG+TG C P CS G C+ NG
Sbjct: 337 EHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGF 396
Query: 294 RCVCNPGYTGE-------DCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC--GTRSCPW 344
+CVC P +TG+ +C + C S + C C PG+ G++C C
Sbjct: 397 KCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 345 DCGEGGRCVD----GRCVCWPGYTGEDCS---TRTCPRDCRGRGRCEDG----ECICDTG 393
C C D RC+C PGY G+ C C G C++ +C+C TG
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTG 516
Query: 394 YSG-------DDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCE 446
+SG D C C R D C C Y G +C + C
Sbjct: 517 FSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHL--------KDHCR 568
Query: 447 NGVC----VCNAGYSGEDC--GVRSCPGD-CRGRGRCESG-----RCMCWPGYTGRDC-- 492
C C + D GVR + C G+C+S C C G+TG C
Sbjct: 569 TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE 628
Query: 493 GTRACPGD-CRGRGRCVDG----RCVCNPGFTG-------EDCGSRRC--PGDCRGHGLC 538
C + CR G C+DG +C+C+ G+ G DC C G CR L
Sbjct: 629 NINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCR--DLV 686
Query: 539 EDGVCVCDAGYSGEDCSTRSC---PGGCRGRGQCLDG----RCVCEDGYSGEDCGVRQ-- 589
D C C G+ G+ C +R C G C D +C+C G+ G C + +
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS 746
Query: 590 --CPNDCSQHGVC----QDGVCICWEGYVSEDCSIRT---CPSNCHGRGRCEEG----RC 636
PN C G C + C+C EG+ C+ T P C+ G C +G RC
Sbjct: 747 SCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRC 806
Query: 637 LCDPGYTGPTCATRM--CPAD-CRGRGRCVQGV----CLCHVGYGGEDCGQEE-----PP 684
C PG+ GP C + C + C CV + C+C G+ G C +
Sbjct: 807 ECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITM 866
Query: 685 ASACPGGCGPRELCRAGQCV-----CVEGFRGP-DCAIQTCPGDCRGRGECHDG-SCV 735
S P G + C QC+ C + + GP C + +G EC G SC+
Sbjct: 867 GSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLH------KGHSECPSGQSCI 918
Score = 216 bits (551), Expect = 3e-55
Identities = 198/699 (28%), Positives = 267/699 (38%), Gaps = 131/699 (18%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC-- 213
C CE WGG C D + P +G C++ G + +C C GY+GP+C
Sbjct: 282 CLCETNWGGQLCD--KDLNYCGTHQPCLNGG---TCSNTGP-DKYQCSCPEGYSGPNCEI 335
Query: 214 GWPSCPGD-CQGRGRCVQG----VCVCRAGFSGPDCSQR---SCPRGCSQRGRCE----G 261
+C D C RG C + C C G++GP CS P CS G C+ G
Sbjct: 336 AEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNG 395
Query: 262 GRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC--GVRSCP 312
+CVC P +TG ++C + C S + + C C PG+ G++C + C
Sbjct: 396 FKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL 455
Query: 313 RGCSQRGRCKD----GRCVCDPGYTGEDC--GTRSCPWD-CGEGGRCVDG----RCVCWP 361
C C+D RC+C PGY G+ C C + C GG C + +C+C
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPT 515
Query: 362 GYTG-------EDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRC 414
G++G + C C + R D C C Y G +C S D + C
Sbjct: 516 GFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNC---SHLKDHCRTTPC 572
Query: 415 E-DGRCVCWPGYTGTDCGSRACPRD-CRGRGRCENG-----VCVCNAGYSGEDC--GVRS 465
E C T G R + C G+C++ C CN G++G C +
Sbjct: 573 EVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND 632
Query: 466 CPGD-CRGRGRCESG----RCMCWPGYTGRDCGTR---ACPGDCRGRGRC----VDGRCV 513
C + CR G C G +C+C G+ G C T C G C D C
Sbjct: 633 CESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCD 692
Query: 514 CNPGFTGEDCGSRRCPGD---CRGHGLCEDG----VCVCDAGYSGEDCS---TRSC-PGG 562
C G+ G+ C SR D C G C D C+C G+ G C+ SC P
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNP 752
Query: 563 CRGRGQCL----DGRCVCEDGYSGEDCGVRQCPNDCSQH-----GVCQDG----VCICWE 609
C G C+ CVC++G+ G C Q NDCS H G C DG C C
Sbjct: 753 CHNGGTCVVNGESFTCVCKEGWEGPICA--QNTNDCSPHPCYNSGTCVDGDNWYRCECAP 810
Query: 610 GYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRMCPADCRGRGRC 662
G+ DC +I C S+ C C + RC+C PG++G C + GR
Sbjct: 811 GFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKC------QEVSGRPCI 864
Query: 663 VQGVCLCHVGYGGEDCGQEEPPASACPGG--------CGPRE-LCRAGQCVCVEGFRG-P 712
G + +DC C G CGPR L G C G P
Sbjct: 865 TMGSVIPDGAKWDDDCN-----TCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIP 919
Query: 713 DCAIQTCPGDCRGRGECHDGSC------VCKDGYAGEDC 745
Q C G GEC S D Y ++C
Sbjct: 920 ILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNC 958
Score = 139 bits (350), Expect = 6e-32
Identities = 128/483 (26%), Positives = 180/483 (37%), Gaps = 86/483 (17%)
Query: 325 RCVCDPGYTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCSTRTCPRDCRGR-G 381
R CD Y G C P D G D G C G+ G +C+ C + C + G
Sbjct: 184 RVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHG 243
Query: 382 RCE-DGECICDTGYSGDDCGVRSCPGDCNQRGRC-EDGRCVCWPGYTGTDCGSRACPRD- 438
C+ G+C C G+ G C + P G C E +C+C T+ G + C +D
Sbjct: 244 SCKLPGDCRCQYGWQGLYCD-KCIPHPGCVHGICNEPWQCLC-----ETNWGGQLCDKDL 297
Query: 439 --CRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDC--GT 494
C C NG G C G + +C C GY+G +C
Sbjct: 298 NYCGTHQPCLNG-------------------GTCSNTGP-DKYQCSCPEGYSGPNCEIAE 337
Query: 495 RACPGD-CRGRGRCVDG----RCVCNPGFTGEDCGSRR---CPGDCRGHGLCEDGV---- 542
AC D C RG C + C C+PG+TG C + P +C G C+D V
Sbjct: 338 HACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397
Query: 543 CVCDAGYSGE-------DCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVR------Q 589
CVC ++G+ +C + C + C C G+ G++C + Q
Sbjct: 398 CVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ 457
Query: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCS--IRTCPSN-CHGRGRCEEG----RCLCDPGY 642
C ND S + CIC GY + C I C SN C G C+ +CLC G+
Sbjct: 458 CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517
Query: 643 TGPTCATRM--C-PADCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACPGGCGPR 695
+G C + C P C+ +C C C Y G++C + P C
Sbjct: 518 SGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTP--CEVI 575
Query: 696 ELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGS-----CVCKDGYAGEDCGEEVP 750
+ C V + P+ C G+C S C C G+ G C E +
Sbjct: 576 DSCT----VAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN 631
Query: 751 TIE 753
E
Sbjct: 632 DCE 634
Score = 67.8 bits (164), Expect = 2e-10
Identities = 65/264 (24%), Positives = 89/264 (33%), Gaps = 91/264 (34%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG----RCVCFPGYTG 210
TC C+ GW GP C+ T + P C + G CV G RC C PG+ G
Sbjct: 767 TCVCKEGWEGPICAQNT------------NDCSPHPCYNSGTCVDGDNWYRCECAPGFAG 814
Query: 211 PSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGY 270
P CR + +C C G + G RCVC PG+
Sbjct: 815 PD----------------------CRININ--ECQSSPCAFGATCVDEINGYRCVCPPGH 850
Query: 271 TGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDP 330
+G C + S R G + + +DC +C +C +GR C
Sbjct: 851 SGAKC------QEVSGRPCITMGSVIPDGAKWDDDC--NTC--------QCLNGRIACSK 894
Query: 331 GYTGEDCGTRSC-----PWDCGEGGRCV---DGRCVCWPGYTGEDCSTRTCPRDCRGRGR 382
+ CG R C +C G C+ D +C P C G G
Sbjct: 895 VW----CGPRPCLLHKGHSECPSGQSCIPILDDQCFVHP---------------CTGVGE 935
Query: 383 CEDG-------ECICDTGYSGDDC 399
C +C D+ Y D+C
Sbjct: 936 CRSSSLQPVKTKCTSDSYYQ-DNC 958
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 231 bits (590), Expect = 9e-60
Identities = 235/826 (28%), Positives = 303/826 (36%), Gaps = 155/826 (18%)
Query: 222 CQGRGRCVQG--------VCVCRAGFSGPDCS---QRSCPRGCSQRGRCEGG----RCVC 266
C G+C+ C C +GF+G C + C G C G RC C
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
Query: 267 DPGYTGDDCGMRSCP---RGCSQRGRC--ENGR--CVCNPGYTGEDC--GVRSC-PRGCS 316
G+ G C P + C G+C ENG CVC GYTG C V C P C
Sbjct: 338 PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCL 397
Query: 317 QRGRCKD----GRCVCDPGYTGEDCGTRSCPWD-------CGEGGRCVDGR----CVCWP 361
G C D C+C + G C T P C GG CVD C C
Sbjct: 398 NGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPE 457
Query: 362 GYTGEDCSTRTCPRDC--RGRGRCEDGE---CICDTGYSGDDCGVRSCPGDCNQRGRCED 416
G+ G DC R P DC R GRC C C G+ G C CN +C D
Sbjct: 458 GFMGLDCRERV-PDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPD 516
Query: 417 GR----------CVCWPGYTGTDCGSRACPRD-CRGRGRCE----NGVCVCNAGYSGEDC 461
G CVC + + C D C G C+ + C C G+ G+ C
Sbjct: 517 GGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 576
Query: 462 GVRS----CPGDCRGRGRCESG----RCMCWPGYTGRDCGT----RACPGDCRGRGRCVD 509
G CR G C+ C C +TGR C G C G C
Sbjct: 577 EKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFH 636
Query: 510 G----RCVCNPGFTGEDCGSRRCP---GDCRGHGLCEDG----VCVCDAGYSGEDCSTRS 558
+C C PGF+G C P C G CED C C AGY G C
Sbjct: 637 YIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEV 696
Query: 559 CPGG--------CRGRGQCLDGRCV--CEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICW 608
G R G L + C+ GYS C HGV + C
Sbjct: 697 DCGPPEEVKHATLRFNGTRLGAVALYACDRGYS---LSAPSRIRVCQPHGVWSEPPQ-CL 752
Query: 609 EGYVSEDCSIRTCPSNCHGRGRCEEG----RCLCDPGYTGPTCATRM--CPAD-CRGRGR 661
E ++C + C HG G C++ CLC GY G C C A CR G
Sbjct: 753 E---IDECRSQPC---LHG-GSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGS 805
Query: 662 C--VQG--VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQ----CVCVEGFRGPD 713
C + G VC C G+ G C E + P G R C +G CVC E F G
Sbjct: 806 CRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGR--CESGGGAYLCVCPESFFGYH 863
Query: 714 CAIQTCP---GDCRGRGEC----HDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVR 766
C + P C GRG C SC CK GY GEDC +E+ ++M +EE+ V
Sbjct: 864 CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVS 923
Query: 767 TEWTPAPGP-----VDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821
W P GP +D Y + ++ + S T V + S++ + LA G+ Y ++V
Sbjct: 924 ISWNPPNGPAARQMLDGYAVTYV--SSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVF 981
Query: 822 ALRGTS-----WGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVS 876
+++ S PA T + V VT +T+ + W + R + VS
Sbjct: 982 SVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQW-----ALHRIRHATVS 1036
Query: 877 AGNQRVR---------LEVPPEADGTLLTDLMPGVEYVVTVTAERG 913
+R +V D L+PG Y + +T G
Sbjct: 1037 GVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSG 1082
Score = 181 bits (459), Expect = 1e-44
Identities = 178/652 (27%), Positives = 229/652 (35%), Gaps = 155/652 (23%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG 214
TCSC G+ G C D S P G+C N RC C G+ GP+C
Sbjct: 296 TCSCLSGFTGRRCH--LDVNECASQPCQNGGTCTHGINSF------RCQCPAGFGGPTCE 347
Query: 215 WPSCPGD---CQGRGRCV----QGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCD 267
P D CQ G+C VCVC+AG++G C
Sbjct: 348 TAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEM--------------------- 386
Query: 268 PGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCP-------RGCSQRGR 320
DDC C G S N C+C + G C P C G
Sbjct: 387 ---DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGT 443
Query: 321 CKDGR----CVCDPGYTGEDCGTR---SCPWDCGEGGRCVDGR---CVCWPGYTGEDCST 370
C D C C G+ G DC R C +C GGRC+ C C G+ G C
Sbjct: 444 CVDADQGYVCECPEGFMGLDCRERVPDDC--ECRNGGRCLGANTTLCQCPLGFFGLLCEF 501
Query: 371 RTCPRDCRGRGRCEDGE----------CICDTGYSGDDCGVRSCPGD-CNQRGRC----E 415
C +C DG C+C T ++ C D C G C +
Sbjct: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
Query: 416 DGRCVCWPGYTGTDCGSRACPRDCRGRGRCENG----------VCVCNAGYSGEDCGV-- 463
C C G+ G C +A P C G C NG C C ++G C +
Sbjct: 562 SYTCECPRGFHGKHC-EKARPHLC-SSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
Query: 464 -RSC-PGDCRGRGRC----ESGRCMCWPGYTGRDCGTRACP---GDCRGRGRC----VDG 510
SC G C G C +C C PG++GR C P C G C D
Sbjct: 620 PDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 511 RCVCNPGFTGE------DCGS----RRCPGDCRGHGLCEDGVCVCDAGYS---------- 550
C C G+ G DCG + G L + CD GYS
Sbjct: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
Query: 551 --------------GEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVR--QC-PND 593
++C ++ C G + + C+C GY G C + +C +
Sbjct: 740 QPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP 799
Query: 594 CSQHGVCQD----GVCICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCDPGY 642
C G C++ VC C G+V C + C S+ C GRCE G C+C +
Sbjct: 800 CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESF 859
Query: 643 TGPTCATRMCP---ADCRGRGRCVQG----VCLCHVGYGGEDCGQEEPPASA 687
G C T P + C GRG C+ C C VGY GEDC +E P +A
Sbjct: 860 FGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTA 911
Score = 87.8 bits (216), Expect = 2e-16
Identities = 88/312 (28%), Positives = 111/312 (35%), Gaps = 63/312 (20%)
Query: 151 LSRCTCSCEPGWGGPTCSDPTDAEIPPS----SPPSASGSCPDDCNDQGRCVRGRCVCFP 206
+ + C C PG+ G C EI PS SP G+C D D C C
Sbjct: 638 IGKYKCDCPPGFSGRHC------EIAPSPCFRSPCVNGGTCEDRDTD------FFCHCQA 685
Query: 207 GYTGPSCGWPSCPGDC-------------QGRGRCVQGVCVCRAGFSGPDCSQRSCPRGC 253
GY G C DC G + C G+S S S R C
Sbjct: 686 GYMGRRC---QAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYS---LSAPSRIRVC 739
Query: 254 SQRG-RCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTG-------ED 305
G E +C+ D+C + C G S + R C+C+ GY G ++
Sbjct: 740 QPHGVWSEPPQCL-----EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDE 794
Query: 306 CGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD---CGEGGRCVDG----RCV 358
C C G S R C C G+ G C T D C GGRC G CV
Sbjct: 795 CRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCV 854
Query: 359 CWPGYTGEDCSTRTCP---RDCRGRGRC----EDGECICDTGYSGDDCGVRSCPGDCNQR 411
C + G C T + P C GRG C C C GY+G+DC P +
Sbjct: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKM 914
Query: 412 GRCED-GRCVCW 422
R E+ G + W
Sbjct: 915 ERVEESGVSISW 926
Score = 58.2 bits (139), Expect = 2e-07
Identities = 67/287 (23%), Positives = 106/287 (36%), Gaps = 23/287 (8%)
Query: 3746 TARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRA-----DSFKVSYQLADGGEPQSVQ 3800
T + L P L+ + E+ ++W PP A D + V+Y +DG ++
Sbjct: 898 TGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDF 957
Query: 3801 VDGQARTQKLQGLIPGARYEVTVVSVRGFEE-----SEPLTGFLTTVPDGPTQLRALNLT 3855
VD + +LQ L G Y ++V SV+ S P T P N+T
Sbjct: 958 VDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVT 1017
Query: 3856 EGFAVLHW---KPPQNPVDTYDVQVTAPGAPPLQAETPGSAVD-YPLHDLVLHTNYT--- 3908
+ W + V V + P A QA +VD + L+ YT
Sbjct: 1018 ASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQL 1077
Query: 3909 ATVRGLRGPNLTSPASITFTTGLEA----PRDLEAKEVTPRTALLTWTEPPVRP--AGYL 3962
T+ GLRG + + T T + P +L A VT +A + W P Y+
Sbjct: 1078 TTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYV 1137
Query: 3963 LSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLP 4009
++ T + G + S+ + L P Y + A+ L P
Sbjct: 1138 INVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGP 1184
Score = 41.2 bits (95), Expect = 0.022
Identities = 63/278 (22%), Positives = 95/278 (34%), Gaps = 46/278 (16%)
Query: 3180 LSLSWTVPQG-----RFDSFTVQYKDRDGQPQVVR-VRGEESEVTVGGLEPGRKYKMHLY 3233
+S+SW P G D + V Y DG + V S + L GR Y + ++
Sbjct: 922 VSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVF 981
Query: 3234 GL-HEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWT---VAQGPFDS 3289
+ +S + P PVE V VT+ ++ + W +
Sbjct: 982 SVKRNSNNKNDISRPAVLLARTRPRPVEG----FEVTNVTASTISVQWALHRIRHATVSG 1037
Query: 3290 FLVQYRDAQG-QPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEA-RTA 3347
V R + + QA V + L P ++Y L L +G R P E+ TA
Sbjct: 1038 VRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL-SGLRGEEHPTESLATA 1096
Query: 3348 PD---TKPSPRLGELTVTDATPDSVGLSWT-------------------------VPEGE 3379
P T+P P LT T S + W VP G+
Sbjct: 1097 PTHVWTRPLPP-ANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGK 1155
Query: 3380 FDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKY 3417
S+ V+ R Q+ +A E+ Q EP+ Y
Sbjct: 1156 LASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLY 1193
Score = 40.0 bits (92), Expect = 0.049
Identities = 68/313 (21%), Positives = 111/313 (35%), Gaps = 47/313 (15%)
Query: 2300 PPIKPRLEELTVTDATPDSLSLSWTVPEG-----QFDHFLVQYKNGDGQPKATRVPGHED 2354
PP ++E + + +S+SW P G D + V Y + DG + T D
Sbjct: 908 PPTALKMERVEES-----GVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRT---DFVD 959
Query: 2355 RVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLL 2414
R S L G R +S V + P++ P+
Sbjct: 960 RTRSSH---------QLQALAAG-RAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVE 1009
Query: 2415 GELTVTGSSPDSLSLSWTVPQGRFDSFT---VQYKDRDG-RPQVVRVGGEESEVTVGGLE 2470
G VT + ++S+ W + + R + + V + + R Q V T L
Sbjct: 1010 G-FEVTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALL 1068
Query: 2471 PGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTV 2530
PG++Y + L L R G P E + +PT T P PP +T
Sbjct: 1069 PGKRYTIQLTTLSGLR--------GEEHPTESL--ATAPTHVWTR-PLPPANLTAARVTA 1117
Query: 2531 TGSSPDSLSLSWTVPQ--GRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKM 2588
T S + W P +++ + G+ + TVR L PGR+Y++
Sbjct: 1118 T-----SAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQL 1172
Query: 2589 HLYGLHEGRRLGP 2601
+ + + LGP
Sbjct: 1173 SVIAV-QSTELGP 1184
Score = 38.9 bits (89), Expect = 0.11
Identities = 63/305 (20%), Positives = 106/305 (34%), Gaps = 53/305 (17%)
Query: 1692 LSWTVPEG-----QFDSFVVQFKDKDGP--QVVPVEGHERSVTVTPLDAGRKYRFLLYGL 1744
+SW P G D + V + DG + V+ S + L AGR Y ++ +
Sbjct: 924 ISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVFSV 983
Query: 1745 LGKKRH-GPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWT---VPE 1800
+ ++ AR+ +PR E +VT VT +++ + W +
Sbjct: 984 KRNSNNKNDISRPAVLLART-----------RPRPVEGFEVTNVTASTISVQWALHRIRH 1032
Query: 1801 GQFDSFVVQYKDRDG-QPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAV 1859
V + + + Q V+ S+ + L P RY + L L
Sbjct: 1033 ATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLS----------- 1081
Query: 1860 AITAGREETETETTAPT-------PPAPEPHLGELTVEEATSHTLHLSW-MVTEGE-FDS 1910
+ TE+ TAPT PPA LT T+ + H+ W T G ++
Sbjct: 1082 GLRGEEHPTESLATAPTHVWTRPLPPA------NLTAARVTATSAHVVWDAPTPGSLLEA 1135
Query: 1911 FEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSD----GKHVGPVHVEAL 1966
+ I T G T+ L RY +++ +H P H+ +
Sbjct: 1136 YVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYII 1195
Query: 1967 TVPEE 1971
T P +
Sbjct: 1196 TSPRD 1200
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 222 bits (565), Expect = 7e-57
Identities = 215/731 (29%), Positives = 282/731 (38%), Gaps = 156/731 (21%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRG-----RCVCFPGYTG 210
C+CE WGG C D S P C + G C+ RC C GY+G
Sbjct: 293 CNCETNWGGLLCD--KDLNYCGSHHP---------CTNGGTCINAEPDQYRCTCPDGYSG 341
Query: 211 PSC--GWPSCPGD-CQGRGRCVQ----GVCVCRAGFSGP-------DCSQRSCPRGCSQR 256
+C +C + C G C + C C +G+SGP +C+ C G +
Sbjct: 342 RNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCV 401
Query: 257 GRCEGGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC--G 307
+ +G C+C + G ++C + C S + C C PG+ G +C
Sbjct: 402 DQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHIN 461
Query: 308 VRSCPRGCSQRGRCKD----GRCVCDPGYTGEDCGTR-----SCPWDCGEGGRCVD---- 354
V C C G CKD +CVC G+ G C S P C GG C D
Sbjct: 462 VNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP--CHSGGLCEDLADG 519
Query: 355 GRCVCWPGYTGEDCSTRT--C-PRDCRGRGRCEDGE----CICDTGYSGDDCGV--RSCP 405
C C G++G C C P CR RC + E C C + G +C V CP
Sbjct: 520 FHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCP 579
Query: 406 GD-CNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC-----ENGVCVCNAGYSGE 459
G C C PG GT A C GRC N C+C++G++G
Sbjct: 580 GGACRVIDGCGSD---AGPGMPGT-----AASGVCGPHGRCVSQPGGNFSCICDSGFTGT 631
Query: 460 DC--GVRSCPGD-CRGRGRC----ESGRCMCWPGYTGRDCGTR---ACPGDCRGRGRCV- 508
C + C G CR G C ++ RC C G+ G C T P C RGRC
Sbjct: 632 YCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 509 ---DGRCVCNPGFTGEDCGSRRCPGD---CRGHGLCEDG----VCVCDAGYSGEDCS--- 555
D C C+ G+ G+ C SR D C G C D C C G+ G C+
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 556 TRSC-PGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDGV--- 604
SC P C G C+ C+C DG+ G C C P C G+C DGV
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 605 -CICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM-CPAD 655
C C G+ DC +I C S+ C C + RC C PG GP C +
Sbjct: 812 RCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRS 871
Query: 656 CRGRG----------------RCVQGVCLC-HVGYGGEDC---GQEEPPASACPGGCGPR 695
C RG RC+ G C V G + C GQ E ++ CP G R
Sbjct: 872 CWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCP--LGQR 929
Query: 696 ELCRA-GQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEG 754
L +A GQC+ P C G+C G E C+ + G+ +C T+
Sbjct: 930 CLEKAPGQCL------RPPCEAW---GEC-GAEEPPSTPCLPRSGHLDNNCAR--LTLHF 977
Query: 755 MRMHLLEETTV 765
R H+ + TTV
Sbjct: 978 NRDHVPQGTTV 988
Score = 206 bits (523), Expect = 5e-52
Identities = 201/713 (28%), Positives = 260/713 (36%), Gaps = 157/713 (22%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCV------CFPGYT 209
C C GW G C D+C CV G CV C +
Sbjct: 262 CRCSYGWQGRFC---------------------DECVPYPGCVHGSCVEPWQCNCETNWG 300
Query: 210 GPSC----GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDC--SQRSCPRG-CSQRG 257
G C + C G C+ Q C C G+SG +C ++ +C C+ G
Sbjct: 301 GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG 360
Query: 258 RCE----GGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC 306
C G C C G++G D+C C G + + + C+C + G C
Sbjct: 361 SCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC 420
Query: 307 GV--RSCP-RGCSQRGRCKD----GRCVCDPGYTGEDC--GTRSCPWDCGEGGRCVD--- 354
+ C + C CK+ C C PG+ G +C C C GG C D
Sbjct: 421 QLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVN 480
Query: 355 -GRCVCWPGYTGEDCSTRT---CPRDCRGRGRCED----GECICDTGYSGDDC--GVRSC 404
+CVC G+ G C C G CED C C G+SG C V C
Sbjct: 481 GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLC 540
Query: 405 -PGDCNQRGRCE----DGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGE 459
P C RC D C C + G +C + PR+ C G C G G
Sbjct: 541 EPSPCRNGARCYNLEGDYYCACPDDFGGKNC---SVPRE-----PCPGGACRVIDG-CGS 591
Query: 460 DCGV----RSCPGDCRGRGRCESG-----RCMCWPGYTGRDCGTRA--CPGD-CRGRGRC 507
D G + G C GRC S C+C G+TG C C G CR G C
Sbjct: 592 DAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTC 651
Query: 508 VDG----RCVCNPGFTGEDCGSRR---CPGDCRGHGLCEDGV----CVCDAGYSGEDCST 556
+D RC C G+ GE C + P C G C D V C CD G+ G+ C +
Sbjct: 652 IDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHS 711
Query: 557 R--SCPG-GCRGRGQCLDG----RCVCEDGYSGEDCGVRQ----CPNDCSQHGVCQDG-- 603
R C C G C D RC C G+ G C V + PN C G C
Sbjct: 712 REFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGA 771
Query: 604 --VCICWEGYVSEDCSIRT--C-PSNCHGRGRCEEG----RCLCDPGYTGPTCATRM--C 652
CIC +G+ C+ T C P C+ G C +G RC C PG+ GP C + C
Sbjct: 772 SFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDEC 831
Query: 653 PAD-CRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASAC-------PGGCGPRELCRA 700
+ C CV + C C G G C + +C P G E C +
Sbjct: 832 QSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS 891
Query: 701 GQCVCVEGFRGPDCAIQTC---PGDCRGRGECHDGSCVCKDGYAGEDCGEEVP 750
C C++G R DC+ C P G+ E C G+ C E+ P
Sbjct: 892 --CRCLDGRR--DCSKVWCGWKPCLLAGQPEALSAQCP-----LGQRCLEKAP 935
Score = 186 bits (473), Expect = 3e-46
Identities = 170/636 (26%), Positives = 228/636 (35%), Gaps = 159/636 (25%)
Query: 263 RCVCDPGYTGDDCGMRSCPRG-------CSQRGRCENGRCVCNPGYTGEDCGVRSCPRGC 315
R CD Y C PR C Q G C G+ G++C C +GC
Sbjct: 195 RVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNK-----ACMDGWMGKECKEAVCKQGC 249
Query: 316 S-QRGRCK-DGRCVCDPGYTGEDC-----------GTRSCPWDCG--------------- 347
+ G C G C C G+ G C G+ PW C
Sbjct: 250 NLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLN 309
Query: 348 ---------EGGRCVDG-----RCVCWPGYTGEDC--STRTCPRD-CRGRGRCED----G 386
GG C++ RC C GY+G +C + C + C G C +
Sbjct: 310 YCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGF 369
Query: 387 ECICDTGYSGDDCG--VRSCPGD-CNQRGRCEDG----RCVCWPGYTGTDC--GSRACP- 436
EC C +G+SG C + C + C G C D C+C + G C + C
Sbjct: 370 ECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG 429
Query: 437 RDCRGRGRCENGV----CVCNAGYSGEDC--GVRSCPGDCRGRGRCE----SGRCMCWPG 486
+ C C+N + C C G+ G +C V C G C+ G C+ +C+C G
Sbjct: 430 KPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRG 489
Query: 487 YTGRDC---GTRACPGDCRGRGRCVD----GRCVCNPGFTG-------EDCGSRRCPGDC 532
+ GR C C G C D C C GF+G + C C
Sbjct: 490 FGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGA 549
Query: 533 RGHGLCEDGVCVCDAGYSGEDCST--RSCPGG------------------------CRGR 566
R + L D C C + G++CS CPGG C
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPH 609
Query: 567 GQCL-----DGRCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDGV----CIC---WEGY 611
G+C+ + C+C+ G++G C + C C G C D V C C WEG
Sbjct: 610 GRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGE 669
Query: 612 VSEDCSIRTCPSNCHGRGRC----EEGRCLCDPGYTGPTCATRMCPAD---CRGRGRCVQ 664
+ + P CH RGRC + C CD G+ G TC +R D C G C
Sbjct: 670 LCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYD 729
Query: 665 G----VCLCHVGYGGEDCGQEEPPASACPGGCGPRELC----RAGQCVCVEGFRGPDCAI 716
C C G+ G C + +S P C C + C+C +G+ G C
Sbjct: 730 SGDTFRCACPPGWKGSTCAVAK-NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTH 788
Query: 717 QT--C-PGDCRGRGECHDG----SCVCKDGYAGEDC 745
T C P C G C DG C C G+AG DC
Sbjct: 789 NTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDC 824
Score = 57.8 bits (138), Expect = 2e-07
Identities = 59/210 (28%), Positives = 73/210 (34%), Gaps = 51/210 (24%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSC-PDDCNDQGRCVRG----RCVCFPGYT 209
+C C GW G TC+ T+ C P C + G CV G RC C PG+
Sbjct: 774 SCICRDGWEGRTCTHNTN-------------DCNPLPCYNGGICVDGVNWFRCECAPGFA 820
Query: 210 GPSC--GWPSCPGD-CQGRGRCVQGV----CVCRAGFSGPDCSQ-----RSC-------P 250
GP C C C CV + C C G +GP C + RSC P
Sbjct: 821 GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFP 880
Query: 251 RGCSQRGRCEGGRCV-----CDPGYTG-DDCGMRSCPRG----CSQRGRC---ENGRCVC 297
G S C RC+ C + G C + P C RC G+C+
Sbjct: 881 HGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLR 940
Query: 298 NPGYTGEDCGVRSCP-RGCSQRGRCKDGRC 326
P +CG P C R D C
Sbjct: 941 PPCEAWGECGAEEPPSTPCLPRSGHLDNNC 970
Score = 36.6 bits (83), Expect = 0.54
Identities = 36/139 (25%), Positives = 51/139 (36%), Gaps = 31/139 (22%)
Query: 148 VFDLSRCTCSCEPGWGGPTCSDPTD---AEIPPSSPPSASGSCPDDCNDQGRCVRGRCVC 204
V +++ CSC PG GP C + + +P S +DCN RC+ GR C
Sbjct: 843 VDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCN-SCRCLDGRRDC 901
Query: 205 FPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRG--CSQRGRCEGG 262
+ CGW C AG P+ CP G C ++ G
Sbjct: 902 SKVW----CGWKPC----------------LLAG--QPEALSAQCPLGQRCLEKA---PG 936
Query: 263 RCVCDPGYTGDDCGMRSCP 281
+C+ P +CG P
Sbjct: 937 QCLRPPCEAWGECGAEEPP 955
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 220 bits (561), Expect = 2e-56
Identities = 114/305 (37%), Positives = 148/305 (48%), Gaps = 36/305 (11%)
Query: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
V +CP +C G C G C C+ G+ G DCG +CP C G G+ G C+C++G+ G +
Sbjct: 563 VDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAE 622
Query: 461 CGV---RSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNP 516
C V + C G C +G C+C PGY G C C C GRG CV G C C+
Sbjct: 623 CDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSV 682
Query: 517 GFTGEDCGSRR--CPGDCRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG 572
G+ G +C + R C C GHG L + G+C CD ++G DCS C C G G C+ G
Sbjct: 683 GWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGG 742
Query: 573 RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI---------RTCPS 623
C CEDG+ G C R C C++HG C+DG C C G+ E C+I CP
Sbjct: 743 TCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
Query: 624 NCHGRGRC----EEGRCLCDPGYTGPTCATRMCPA-------------DCRGRGRCVQGV 666
C+G GRC C+C G+ G C T M A DC C+Q
Sbjct: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP- 861
Query: 667 CLCHV 671
LCH+
Sbjct: 862 -LCHI 865
Score = 215 bits (547), Expect = 9e-55
Identities = 107/266 (40%), Positives = 130/266 (48%), Gaps = 21/266 (7%)
Query: 217 SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276
+CP +C G G C+ G C C GF GPDC + SCP CS G+ GRC+C G+ G +C
Sbjct: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
Query: 277 M---RSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCKDGRCVCDPGY 332
+ + CS G C G C+CNPGY GE C C CS RG C G C C G+
Sbjct: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
Query: 333 TGEDCGT--RSCPWDCGEGGRCVD--GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGEC 388
G +C T +C C G + G C C P +TG DCS C DC G G C G C
Sbjct: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
Query: 389 ICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCG---------SRACPRDC 439
C+ G+ G C R+C C + G C DG+C C PG+ G C CP C
Sbjct: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
Query: 440 RGRGRCE---NG-VCVCNAGYSGEDC 461
G GRC NG CVC G+ G C
Sbjct: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC 830
Score = 213 bits (541), Expect = 4e-54
Identities = 102/266 (38%), Positives = 130/266 (48%), Gaps = 21/266 (7%)
Query: 186 SCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDC- 244
+CP +C G C+ G C CF G+ GP CG SCP C G G+ ++G C+C +G+ G +C
Sbjct: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
Query: 245 --SQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSC-PRGCSQRGRCENGRCVCNPGY 301
+ + CS G C G C+C+PGY G+ C C CS RG C G C C+ G+
Sbjct: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
Query: 302 TGEDCGV--RSCPRGCSQRGRC--KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRC 357
G +C +C CS G G C CDP +TG DC C DCG G CV G C
Sbjct: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
Query: 358 VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGV---------RSCPGDC 408
C G+ G C R C C G C DG+C C G++G+ C + CPG C
Sbjct: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
Query: 409 NQRGRC----EDGRCVCWPGYTGTDC 430
N GRC CVC G+ G C
Sbjct: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC 830
Score = 209 bits (533), Expect = 4e-53
Identities = 110/297 (37%), Positives = 135/297 (45%), Gaps = 28/297 (9%)
Query: 248 SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
+CP C G C G C C G+ G DCG SCP CS G+ GRC+C+ G+ G +C
Sbjct: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
Query: 308 V---RSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSC-PWDCGEGGRCVDGRCVCWPGY 363
V + CS G C G C+C+PGY GE C C C G CV G C C G+
Sbjct: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
Query: 364 TGEDCST--RTCPRDCRGRGRC--EDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRC 419
G +C T TC C G G + G C CD ++G DC + C DC G C G C
Sbjct: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
Query: 420 VCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGV---------RSCPGDC 470
C G+ G C RAC C G C +G C C+ G++GE C + CPG C
Sbjct: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
Query: 471 RGRGRC----ESGRCMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNP 516
G GRC C+C G+ G C T AC D G C+D C P
Sbjct: 805 NGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP 861
Score = 208 bits (530), Expect = 8e-53
Identities = 107/295 (36%), Positives = 141/295 (47%), Gaps = 23/295 (7%)
Query: 463 VRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGED 522
V +CP +C G G C SG C C+ G+ G DCG +CP C G G+ + GRC+C+ G+ G +
Sbjct: 563 VDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAE 622
Query: 523 CG--SRRCPG-DCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCED 578
C + +C C HG C G C+C+ GY GE C C C GRG C+ G C C
Sbjct: 623 CDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSV 682
Query: 579 GYSGEDCGVRQ--CPNDCSQHGVC--QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG 634
G+ G +C + C + CS HG G+C C + DCSI C ++C G G C G
Sbjct: 683 GWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGG 742
Query: 635 RCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCG----QEEPPASACPG 690
C C+ G+ G C R C C G C G C C G+ GE C + CPG
Sbjct: 743 TCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
Query: 691 GCGPRELC----RAGQCVCVEGFRGPDC--AIQTCPGDCR-----GRGECHDGSC 734
C C CVC G+RG C +++T GD + G +C D C
Sbjct: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDC 857
Score = 204 bits (519), Expect = 2e-51
Identities = 108/315 (34%), Positives = 138/315 (43%), Gaps = 36/315 (11%)
Query: 308 VRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGED 367
V +CP C G C G C C G+ G DCG SCP C G+ + GRC+C G+ G +
Sbjct: 563 VDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAE 622
Query: 368 CSTRT---CPRDCRGRGRCEDGECICDTGYSGDDCGVRSC-PGDCNQRGRCEDGRCVCWP 423
C T C G C G CIC+ GY G+ C C C+ RG C G C C
Sbjct: 623 CDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSV 682
Query: 424 GYTGTDCGS--RACPRDCRGRGRC--ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESG 479
G+ GT+C + C C G G + G+C C+ ++G DC + C DC G G C G
Sbjct: 683 GWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGG 742
Query: 480 RCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG---------SRRCPG 530
C C G+ G C RAC C G C DG+C C+PG+ GE C CPG
Sbjct: 743 TCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
Query: 531 DCRGHGLCEDGV----CVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCG 586
C G+G C + CVC G+ G C T C D + G
Sbjct: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSM--------------ETACGDSKDNDGDG 848
Query: 587 VRQCPN-DCSQHGVC 600
+ C + DC +C
Sbjct: 849 LVDCMDPDCCLQPLC 863
Score = 202 bits (515), Expect = 4e-51
Identities = 105/279 (37%), Positives = 129/279 (46%), Gaps = 26/279 (9%)
Query: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCS- 555
CP +C G G C+ G C C GF G DCG CP C G+G G C+C +G+ G +C
Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
Query: 556 -TRSCPG-GCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612
T C C G C+ G C+C GY GE C C + CS GVC G C C G+
Sbjct: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWG 685
Query: 613 SEDCSI--RTCPSNCHGRGRC--EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668
+C TC C G G + G C CDP +TG C+ +C ADC G G CV G C
Sbjct: 686 GTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR 745
Query: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAI---------QTC 719
C G+ G C Q AC C CR G+C C G+ G C I + C
Sbjct: 746 CEDGWMGAACDQR-----ACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGC 800
Query: 720 PGDCRGRGEC----HDGSCVCKDGYAGEDCGEEVPTIEG 754
PG C G G C + CVC+ G+ G C + T G
Sbjct: 801 PGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACG 839
Score = 176 bits (446), Expect = 4e-43
Identities = 92/275 (33%), Positives = 120/275 (43%), Gaps = 36/275 (13%)
Query: 146 HGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCF 205
+G D TC C G+ GP C SCP C+ G+ ++GRC+C
Sbjct: 571 YGNGDCISGTCHCFLGFLGPDCG---------------RASCPVLCSGNGQYMKGRCLCH 615
Query: 206 PGYTGPSCGWPS---CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSC-PRGCSQRGRCEG 261
G+ G C P+ C G C+ G C+C G+ G C + C CS RG C
Sbjct: 616 SGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVR 675
Query: 262 GRCVCDPGYTGDDC--GMRSCPRGCSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQ 317
G C C G+ G +C +C CS G + G C C+P +TG DC + C C
Sbjct: 676 GECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGG 735
Query: 318 RGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCS-------- 369
G C G C C+ G+ G C R+C C E G C DG+C C PG+ GE C+
Sbjct: 736 HGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRV 795
Query: 370 -TRTCPRDCRGRGRC----EDGECICDTGYSGDDC 399
CP C G GRC C+C G+ G C
Sbjct: 796 VKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
Score = 173 bits (439), Expect = 3e-42
Identities = 94/275 (34%), Positives = 122/275 (44%), Gaps = 34/275 (12%)
Query: 135 GQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQ 194
G+ LCS +G + RC C GW G C PT+ I + C++
Sbjct: 593 GRASCPVLCSGNGQYMKGRCLC--HSGWKGAECDVPTNQCIDVA------------CSNH 638
Query: 195 GRCVRGRCVCFPGYTGPSCGWPSCPGD-CQGRGRCVQGVCVCRAGFSGPDCS--QRSCPR 251
G C+ G C+C PGY G SC C C GRG CV+G C C G+ G +C + +C
Sbjct: 639 GTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLD 698
Query: 252 GCSQRGRC--EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVR 309
CS G + G C CDP +TG DC + C C G C G C C G+ G C R
Sbjct: 699 QCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQR 758
Query: 310 SCPRGCSQRGRCKDGRCVCDPGYTGEDCG---------TRSCPWDCGEGGRCV----DGR 356
+C C++ G C+DG+C C PG+ GE C CP C GRC
Sbjct: 759 ACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWH 818
Query: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICD 391
CVC G+ G C T G + DG+ + D
Sbjct: 819 CVCQLGWRGAGCDTSM--ETACGDSKDNDGDGLVD 851
Score = 160 bits (404), Expect = 3e-38
Identities = 77/199 (38%), Positives = 99/199 (49%), Gaps = 9/199 (4%)
Query: 555 STRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSE 614
S +CP C G G C+ G C C G+ G DCG CP CS +G G C+C G+
Sbjct: 562 SVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGA 621
Query: 615 DCSIRT---CPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVCLCH 670
+C + T C G C G C+C+PGY G +C C C GRG CV+G C C
Sbjct: 622 ECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCS 681
Query: 671 VGYGGEDCGQEEPPASACPGGCGPRE--LCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
VG+GG +C E P + C C L G C C + G DC+I+ C DC G G
Sbjct: 682 VGWGGTNC---ETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGV 738
Query: 729 CHDGSCVCKDGYAGEDCGE 747
C G+C C+DG+ G C +
Sbjct: 739 CVGGTCRCEDGWMGAACDQ 757
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 212 bits (540), Expect = 6e-54
Identities = 212/734 (28%), Positives = 274/734 (37%), Gaps = 169/734 (23%)
Query: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCV------CFPGYT 209
C C GW G C D+C CV G CV C +
Sbjct: 262 CRCSYGWQGRFC---------------------DECVPYPGCVHGSCVEPWQCNCETNWG 300
Query: 210 GPSC----GWPSCPGDCQGRGRCV-----QGVCVCRAGFSGPDC--SQRSCPRG-CSQRG 257
G C + C G C+ Q C C G+SG +C ++ +C C+ G
Sbjct: 301 GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG 360
Query: 258 RC----EGGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDC 306
C G C C G++G D+C C G + + + C+C + G C
Sbjct: 361 SCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC 420
Query: 307 --GVRSCPRGCSQRGRCKD----GRCVCDPGYTGEDCGTR-----SCPWDCGEGGRCVD- 354
V C C G CKD +CVC G+ G C S P C GG C D
Sbjct: 421 QLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP--CHSGGLCEDL 478
Query: 355 ---GRCVCWPGYTGEDCSTRT--C-PRDCRGRGRCEDGE----CICDTGYSGDDCGV--R 402
C C G++G C C P CR RC + E C C + G +C V
Sbjct: 479 ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 538
Query: 403 SCPGD-CNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC-----ENGVCVCNAGY 456
CPG C C PG GT A C GRC N C+C++G+
Sbjct: 539 PCPGGACRVIDGCGSD---AGPGMPGT-----AASGVCGPHGRCVSQPGGNFSCICDSGF 590
Query: 457 SGEDC--GVRSCPGD-CRGRGRC----ESGRCMCWPGYTGRDCGTR---ACPGDCRGRGR 506
+G C + C G CR G C ++ RC C G+ G C T P C RGR
Sbjct: 591 TGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGR 650
Query: 507 CV----DGRCVCNPGFTGEDCGSRRCPGD---CRGHGLCEDG----VCVCDAGYSGEDCS 555
C D C C+ G+ G+ C SR D C G C D C C G+ G C+
Sbjct: 651 CYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCA 710
Query: 556 ---TRSC-PGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQC-PNDCSQHGVCQDGV 604
SC P C G C+ C+C DG+ G C C P C G+C DGV
Sbjct: 711 VAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGV 770
Query: 605 ----CICWEGYVSEDC--SIRTCPSN-CHGRGRCEEG----RCLCDPGYTGPTCATRM-C 652
C C G+ DC +I C S+ C C + RC C PG GP C +
Sbjct: 771 NWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGF 830
Query: 653 PADCRGRG----------------RCVQGVCLC-HVGYGGEDC---GQEEPPASACPGGC 692
C RG RC+ G C V G + C GQ E ++ CP
Sbjct: 831 GRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCP--L 888
Query: 693 GPRELCRA-GQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPT 751
G R L +A GQC+ P C G+C G E C+ + G+ +C T
Sbjct: 889 GQRCLEKAPGQCL------RPPCEAW---GEC-GAEEPPSTPCLPRSGHLDNNCAR--LT 936
Query: 752 IEGMRMHLLEETTV 765
+ R H+ + TTV
Sbjct: 937 LHFNRDHVPQGTTV 950
Score = 209 bits (531), Expect = 6e-53
Identities = 193/680 (28%), Positives = 250/680 (36%), Gaps = 138/680 (20%)
Query: 200 GRCVCFPGYTGPSCGWPSCPGDCQG-RGRC-VQGVCVCRAGFSGPDCSQRSCPRGCSQRG 257
G C G+ G C C C G C V G C C G+ G C + GC
Sbjct: 227 GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGS 286
Query: 258 RCEGGRCVCDPGYTG----DDCGMRSCPRGCSQRGRCENG-----RCVCNPGYTGEDC-- 306
E +C C+ + G D C+ G C N RC C GY+G +C
Sbjct: 287 CVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK 346
Query: 307 GVRSCPRG-CSQRGRCKDG----RCVCDPGYTGEDCGTR--SCPWD-CGEGGRCVDG--- 355
+C C+ G C + C C G++G C C + C GG CVD
Sbjct: 347 AEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG 406
Query: 356 -RCVCWPGYTGEDCS--TRTCPRDCRGRGRCED----GECICDTGYSGDDCGVRS---CP 405
C+C + G C C C+ G C+D +C+C G+ G C +
Sbjct: 407 FECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECAS 466
Query: 406 GDCNQRGRCED----GRCVCWPGYTGTDCGSRA--C-PRDCRGRGRCEN----GVCVCNA 454
C+ G CED C C G++G C C P CR RC N C C
Sbjct: 467 SPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD 526
Query: 455 GYSGEDCGV--RSCPGD------------------------CRGRGRCESG-----RCMC 483
+ G++C V CPG C GRC S C+C
Sbjct: 527 DFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC 586
Query: 484 WPGYTGRDCGTRA--CPGD-CRGRGRCVDG----RCVCNPGFTGEDCGSRR---CPGDCR 533
G+TG C C G CR G C+D RC C G+ GE C + P C
Sbjct: 587 DSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCH 646
Query: 534 GHGLCEDGV----CVCDAGYSGEDCSTR--SCPG-GCRGRGQCLDG----RCVCEDGYSG 582
G C D V C CD G+ G+ C +R C C G C D RC C G+ G
Sbjct: 647 SRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG 706
Query: 583 EDCGVRQ----CPNDCSQHGVCQDG----VCICWEGYVSEDCSIRT--C-PSNCHGRGRC 631
C V + PN C G C CIC +G+ C+ T C P C+ G C
Sbjct: 707 STCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGIC 766
Query: 632 EEG----RCLCDPGYTGPTCATRM--CPAD-CRGRGRCVQGV----CLCHVGYGGEDCGQ 680
+G RC C PG+ GP C + C + C CV + C C G G C +
Sbjct: 767 VDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQE 826
Query: 681 EEPPASAC-------PGGCGPRELCRAGQCVCVEGFRGPDCAIQTC---PGDCRGRGECH 730
+C P G E C + C C++G R DC+ C P G+ E
Sbjct: 827 VIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLDGRR--DCSKVWCGWKPCLLAGQPEAL 882
Query: 731 DGSCVCKDGYAGEDCGEEVP 750
C G+ C E+ P
Sbjct: 883 SAQCP-----LGQRCLEKAP 897
Score = 57.8 bits (138), Expect = 2e-07
Identities = 59/210 (28%), Positives = 73/210 (34%), Gaps = 51/210 (24%)
Query: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSC-PDDCNDQGRCVRG----RCVCFPGYT 209
+C C GW G TC+ T+ C P C + G CV G RC C PG+
Sbjct: 736 SCICRDGWEGRTCTHNTN-------------DCNPLPCYNGGICVDGVNWFRCECAPGFA 782
Query: 210 GPSC--GWPSCPGD-CQGRGRCVQGV----CVCRAGFSGPDCSQ-----RSC-------P 250
GP C C C CV + C C G +GP C + RSC P
Sbjct: 783 GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFP 842
Query: 251 RGCSQRGRCEGGRCV-----CDPGYTG-DDCGMRSCPRG----CSQRGRC---ENGRCVC 297
G S C RC+ C + G C + P C RC G+C+
Sbjct: 843 HGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLR 902
Query: 298 NPGYTGEDCGVRSCP-RGCSQRGRCKDGRC 326
P +CG P C R D C
Sbjct: 903 PPCEAWGECGAEEPPSTPCLPRSGHLDNNC 932
Score = 36.6 bits (83), Expect = 0.54
Identities = 36/139 (25%), Positives = 51/139 (36%), Gaps = 31/139 (22%)
Query: 148 VFDLSRCTCSCEPGWGGPTCSDPTD---AEIPPSSPPSASGSCPDDCNDQGRCVRGRCVC 204
V +++ CSC PG GP C + + +P S +DCN RC+ GR C
Sbjct: 805 VDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCN-SCRCLDGRRDC 863
Query: 205 FPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRG--CSQRGRCEGG 262
+ CGW C AG P+ CP G C ++ G
Sbjct: 864 SKVW----CGWKPC----------------LLAG--QPEALSAQCPLGQRCLEKA---PG 898
Query: 263 RCVCDPGYTGDDCGMRSCP 281
+C+ P +CG P
Sbjct: 899 QCLRPPCEAWGECGAEEPP 917
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 205 bits (522), Expect = 7e-52
Identities = 107/266 (40%), Positives = 130/266 (48%), Gaps = 20/266 (7%)
Query: 218 CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGM 277
C +C G G C+ G C C GF GPDC++ SCP C G E G CVC G+ G +C +
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 278 ---RSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCKDGRCVCDPGYT 333
+ C G C G C+C PGY GE C C CS G C G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 334 GEDCGTRS--CPWDC-GEGGRCVD-GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI 389
G +C T C C G G +D G C C P +TG DCST C +C G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 390 CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCG--------SRACPRDCRG 441
C+ G+ G C RSC C + G+C+DG+C C PG+ G C CP C G
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 771
Query: 442 RGRC---ENG-VCVCNAGYSGEDCGV 463
GRC +NG CVC G+SG C V
Sbjct: 772 NGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 199 bits (506), Expect = 5e-50
Identities = 110/323 (34%), Positives = 140/323 (43%), Gaps = 43/323 (13%)
Query: 366 EDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGY 425
+DCST +C G G C G C C G+ G DC SCP C G E G CVC G+
Sbjct: 530 DDCST-----NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 584
Query: 426 TGTDCG---SRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD-CRGRGRCESGRC 481
G +C + C G G C GVC+C GY GE C C C G C G C
Sbjct: 585 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 644
Query: 482 MCWPGYTGRDCGTR--ACPGDCRGRGRCV--DGRCVCNPGFTGEDCGSRRCPGDCRGHGL 537
C G+ G +C T C C G G + G C C+P +TG DC + C +C HG+
Sbjct: 645 HCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGV 704
Query: 538 CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQ-------- 589
C G+C C+ G+ G C RSC C GQC DG+C C G+ G+ C +
Sbjct: 705 CSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDG 764
Query: 590 CPNDCSQHGVC---QDG-VCICWEGYVSEDCSI---RTCPSNCHGRGR----------CE 632
CP C +G C Q+G C+C G+ C++ C N G C+
Sbjct: 765 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQ 824
Query: 633 EGRCLCDPGYTGPTCATRMCPAD 655
+ C Y P C P D
Sbjct: 825 QSNC-----YISPLCQGSPDPLD 842
Score = 197 bits (501), Expect = 2e-49
Identities = 103/291 (35%), Positives = 127/291 (43%), Gaps = 22/291 (7%)
Query: 466 CPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG- 524
C +C G G C SG C C+PG+ G DC +CP C G G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 525 -SRRC-PGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGYS 581
+C C GHG C GVC+C GY GE C C C G C+ G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 582 GEDCG--VRQCPNDCSQHG--VCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCL 637
G +C + C CS HG + GVC C + DCS C C G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 638 CDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDC---GQEEPPASACPGGCGP 694
C+ G+ GPTC R C + C G+C G C C G+ G+ C + CPG C
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 771
Query: 695 RELCRAGQ----CVCVEGFRGPDCAI-------QTCPGDCRGRGECHDGSC 734
C Q CVC G+ G C + D G +C D C
Sbjct: 772 NGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC 822
Score = 195 bits (495), Expect = 9e-49
Identities = 96/269 (35%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
C +C G G C+ G C C PGF G DC CP C G+G E G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 557 ---RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612
+ C G G C+ G C+C GY GE C C + CS HG+C G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 613 SEDCS--IRTCPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668
+C + C C G G + G C CDP +TG C+T +C +C G C +G+C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAI--------QTCP 720
C G+ G C + +C C C+ G+C C G+ G C I CP
Sbjct: 712 CEEGWVGPTCEER-----SCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCP 766
Query: 721 GDCRGRGEC----HDGSCVCKDGYAGEDC 745
G C G G C + CVC+ G++G C
Sbjct: 767 GLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 172 bits (437), Expect = 5e-42
Identities = 102/339 (30%), Positives = 134/339 (39%), Gaps = 51/339 (15%)
Query: 99 EVQALRVRLEILEELVKGLKE--QCTGG---CCPASAQAGTGQTDVRTLCSLHGVFDLSR 153
+V L +EI+++ +C G C P + LC +G ++
Sbjct: 518 QVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH 577
Query: 154 CTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC 213
C C GW GP C P + I P+ C G C+ G C+C PGY G C
Sbjct: 578 CVC--RHGWKGPECDVPEEQCIDPT------------CFGHGTCIMGVCICVPGYKGEIC 623
Query: 214 GWPSCPGD-CQGRGRCVQGVCVCRAGFSGPDCSQRS--CPRGCSQRGR--CEGGRCVCDP 268
C C G CV+G C C G+ G +C C CS G + G C CDP
Sbjct: 624 EEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDP 683
Query: 269 GYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVC 328
+TG DC C C G C G C C G+ G C RSC C++ G+CKDG+C C
Sbjct: 684 KWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCEC 743
Query: 329 DPGYTGEDCGTR--------SCPWDCGEGGRCV----DGRCVCWPGYTGEDCSTRTCPRD 376
PG+ G+ C CP C GRC CVC G++G C+
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVM---- 799
Query: 377 CRGRGRCEDGECICDTGYSGDDCGVRSC-PGDCNQRGRC 414
E +C D G+ C DC Q+ C
Sbjct: 800 ----------EMLCGDNLDNDGDGLTDCVDPDCCQQSNC 828
Score = 143 bits (361), Expect = 3e-33
Identities = 71/202 (35%), Positives = 93/202 (46%), Gaps = 14/202 (6%)
Query: 552 EDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGY 611
+DCST C G G+C+ G C C G+ G DC CP C +G + G C+C G+
Sbjct: 530 DDCSTN-----CNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 584
Query: 612 VSEDCSI---RTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVC 667
+C + + C G G C G C+C PGY G C C C G CV+G C
Sbjct: 585 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 644
Query: 668 LCHVGYGGEDCGQEEPPASACPGGCGPRE--LCRAGQCVCVEGFRGPDCAIQTCPGDCRG 725
C G+GG +C E P C C L AG C C + G DC+ + C +C
Sbjct: 645 HCSTGWGGVNC---ETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGS 701
Query: 726 RGECHDGSCVCKDGYAGEDCGE 747
G C G C C++G+ G C E
Sbjct: 702 HGVCSRGICQCEEGWVGPTCEE 723
Score = 118 bits (295), Expect = 1e-25
Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Query: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649
C +C+ +G C G C C+ G++ DC+ +CP C G G E+G C+C G+ GP C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 650 ---RMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706
+ C G G C+ GVC+C GY GE C +E+ C +C G+C C
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEED----CLDPMCSNHGICVKGECHCS 647
Query: 707 EGFRGPDCA--IQTCPGDCRGRGE--CHDGSCVCKDGYAGEDCGEEVPTIE 753
G+ G +C + C C G G G C C + G DC E+ T+E
Sbjct: 648 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTME 698
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 205 bits (522), Expect = 7e-52
Identities = 107/266 (40%), Positives = 130/266 (48%), Gaps = 20/266 (7%)
Query: 218 CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGM 277
C +C G G C+ G C C GF GPDC++ SCP C G E G CVC G+ G +C +
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 278 ---RSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCKDGRCVCDPGYT 333
+ C G C G C+C PGY GE C C CS G C G C C G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 334 GEDCGTRS--CPWDC-GEGGRCVD-GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI 389
G +C T C C G G +D G C C P +TG DCST C +C G C G C
Sbjct: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710
Query: 390 CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCG--------SRACPRDCRG 441
C+ G+ G C RSC C + G+C+DG+C C PG+ G C CP C G
Sbjct: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770
Query: 442 RGRC---ENG-VCVCNAGYSGEDCGV 463
GRC +NG CVC G+SG C V
Sbjct: 771 NGRCTLDQNGWHCVCQVGWSGTGCNV 796
Score = 199 bits (506), Expect = 5e-50
Identities = 110/323 (34%), Positives = 140/323 (43%), Gaps = 43/323 (13%)
Query: 366 EDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGY 425
+DCST +C G G C G C C G+ G DC SCP C G E G CVC G+
Sbjct: 529 DDCST-----NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 583
Query: 426 TGTDCG---SRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD-CRGRGRCESGRC 481
G +C + C G G C GVC+C GY GE C C C G C G C
Sbjct: 584 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 643
Query: 482 MCWPGYTGRDCGTR--ACPGDCRGRGRCV--DGRCVCNPGFTGEDCGSRRCPGDCRGHGL 537
C G+ G +C T C C G G + G C C+P +TG DC + C +C HG+
Sbjct: 644 HCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGV 703
Query: 538 CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQ-------- 589
C G+C C+ G+ G C RSC C GQC DG+C C G+ G+ C +
Sbjct: 704 CSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDG 763
Query: 590 CPNDCSQHGVC---QDG-VCICWEGYVSEDCSI---RTCPSNCHGRGR----------CE 632
CP C +G C Q+G C+C G+ C++ C N G C+
Sbjct: 764 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQ 823
Query: 633 EGRCLCDPGYTGPTCATRMCPAD 655
+ C Y P C P D
Sbjct: 824 QSNC-----YISPLCQGSPDPLD 841
Score = 197 bits (501), Expect = 2e-49
Identities = 103/291 (35%), Positives = 127/291 (43%), Gaps = 22/291 (7%)
Query: 466 CPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG- 524
C +C G G C SG C C+PG+ G DC +CP C G G G CVC G+ G +C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 525 -SRRC-PGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGYS 581
+C C GHG C GVC+C GY GE C C C G C+ G C C G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 582 GEDCG--VRQCPNDCSQHG--VCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCL 637
G +C + C CS HG + GVC C + DCS C C G C G C
Sbjct: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710
Query: 638 CDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDC---GQEEPPASACPGGCGP 694
C+ G+ GPTC R C + C G+C G C C G+ G+ C + CPG C
Sbjct: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770
Query: 695 RELCRAGQ----CVCVEGFRGPDCAI-------QTCPGDCRGRGECHDGSC 734
C Q CVC G+ G C + D G +C D C
Sbjct: 771 NGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC 821
Score = 195 bits (495), Expect = 9e-49
Identities = 96/269 (35%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
C +C G G C+ G C C PGF G DC CP C G+G E G CVC G+ G +C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 557 ---RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612
+ C G G C+ G C+C GY GE C C + CS HG+C G C C G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 613 SEDCS--IRTCPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668
+C + C C G G + G C CDP +TG C+T +C +C G C +G+C
Sbjct: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710
Query: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAI--------QTCP 720
C G+ G C + +C C C+ G+C C G+ G C I CP
Sbjct: 711 CEEGWVGPTCEER-----SCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCP 765
Query: 721 GDCRGRGEC----HDGSCVCKDGYAGEDC 745
G C G G C + CVC+ G++G C
Sbjct: 766 GLCFGNGRCTLDQNGWHCVCQVGWSGTGC 794
Score = 172 bits (437), Expect = 5e-42
Identities = 102/339 (30%), Positives = 134/339 (39%), Gaps = 51/339 (15%)
Query: 99 EVQALRVRLEILEELVKGLKE--QCTGG---CCPASAQAGTGQTDVRTLCSLHGVFDLSR 153
+V L +EI+++ +C G C P + LC +G ++
Sbjct: 517 QVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH 576
Query: 154 CTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC 213
C C GW GP C P + I P+ C G C+ G C+C PGY G C
Sbjct: 577 CVC--RHGWKGPECDVPEEQCIDPT------------CFGHGTCIMGVCICVPGYKGEIC 622
Query: 214 GWPSCPGD-CQGRGRCVQGVCVCRAGFSGPDCSQRS--CPRGCSQRGR--CEGGRCVCDP 268
C C G CV+G C C G+ G +C C CS G + G C CDP
Sbjct: 623 EEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDP 682
Query: 269 GYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVC 328
+TG DC C C G C G C C G+ G C RSC C++ G+CKDG+C C
Sbjct: 683 KWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCEC 742
Query: 329 DPGYTGEDCGTR--------SCPWDCGEGGRCV----DGRCVCWPGYTGEDCSTRTCPRD 376
PG+ G+ C CP C GRC CVC G++G C+
Sbjct: 743 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVM---- 798
Query: 377 CRGRGRCEDGECICDTGYSGDDCGVRSC-PGDCNQRGRC 414
E +C D G+ C DC Q+ C
Sbjct: 799 ----------EMLCGDNLDNDGDGLTDCVDPDCCQQSNC 827
Score = 143 bits (361), Expect = 3e-33
Identities = 71/202 (35%), Positives = 93/202 (46%), Gaps = 14/202 (6%)
Query: 552 EDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGY 611
+DCST C G G+C+ G C C G+ G DC CP C +G + G C+C G+
Sbjct: 529 DDCSTN-----CNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 583
Query: 612 VSEDCSI---RTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVC 667
+C + + C G G C G C+C PGY G C C C G CV+G C
Sbjct: 584 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 643
Query: 668 LCHVGYGGEDCGQEEPPASACPGGCGPRE--LCRAGQCVCVEGFRGPDCAIQTCPGDCRG 725
C G+GG +C E P C C L AG C C + G DC+ + C +C
Sbjct: 644 HCSTGWGGVNC---ETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGS 700
Query: 726 RGECHDGSCVCKDGYAGEDCGE 747
G C G C C++G+ G C E
Sbjct: 701 HGVCSRGICQCEEGWVGPTCEE 722
Score = 118 bits (295), Expect = 1e-25
Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Query: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649
C +C+ +G C G C C+ G++ DC+ +CP C G G E+G C+C G+ GP C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 650 ---RMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706
+ C G G C+ GVC+C GY GE C +E+ C +C G+C C
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEED----CLDPMCSNHGICVKGECHCS 646
Query: 707 EGFRGPDCA--IQTCPGDCRGRGE--CHDGSCVCKDGYAGEDCGEEVPTIE 753
G+ G +C + C C G G G C C + G DC E+ T+E
Sbjct: 647 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTME 697
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 205 bits (522), Expect = 7e-52
Identities = 107/266 (40%), Positives = 130/266 (48%), Gaps = 20/266 (7%)
Query: 218 CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGM 277
C +C G G C+ G C C GF GPDC++ SCP C G E G CVC G+ G +C +
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 278 ---RSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCKDGRCVCDPGYT 333
+ C G C G C+C PGY GE C C CS G C G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 334 GEDCGTRS--CPWDC-GEGGRCVD-GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECI 389
G +C T C C G G +D G C C P +TG DCST C +C G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 390 CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCG--------SRACPRDCRG 441
C+ G+ G C RSC C + G+C+DG+C C PG+ G C CP C G
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 771
Query: 442 RGRC---ENG-VCVCNAGYSGEDCGV 463
GRC +NG CVC G+SG C V
Sbjct: 772 NGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 199 bits (506), Expect = 5e-50
Identities = 110/323 (34%), Positives = 140/323 (43%), Gaps = 43/323 (13%)
Query: 366 EDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGY 425
+DCST +C G G C G C C G+ G DC SCP C G E G CVC G+
Sbjct: 530 DDCST-----NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 584
Query: 426 TGTDCG---SRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD-CRGRGRCESGRC 481
G +C + C G G C GVC+C GY GE C C C G C G C
Sbjct: 585 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 644
Query: 482 MCWPGYTGRDCGTR--ACPGDCRGRGRCV--DGRCVCNPGFTGEDCGSRRCPGDCRGHGL 537
C G+ G +C T C C G G + G C C+P +TG DC + C +C HG+
Sbjct: 645 HCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGV 704
Query: 538 CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQ-------- 589
C G+C C+ G+ G C RSC C GQC DG+C C G+ G+ C +
Sbjct: 705 CSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDG 764
Query: 590 CPNDCSQHGVC---QDG-VCICWEGYVSEDCSI---RTCPSNCHGRGR----------CE 632
CP C +G C Q+G C+C G+ C++ C N G C+
Sbjct: 765 CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQ 824
Query: 633 EGRCLCDPGYTGPTCATRMCPAD 655
+ C Y P C P D
Sbjct: 825 QSNC-----YISPLCQGSPDPLD 842
Score = 197 bits (501), Expect = 2e-49
Identities = 103/291 (35%), Positives = 127/291 (43%), Gaps = 22/291 (7%)
Query: 466 CPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG- 524
C +C G G C SG C C+PG+ G DC +CP C G G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 525 -SRRC-PGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGYS 581
+C C GHG C GVC+C GY GE C C C G C+ G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 582 GEDCG--VRQCPNDCSQHG--VCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCL 637
G +C + C CS HG + GVC C + DCS C C G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 638 CDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDC---GQEEPPASACPGGCGP 694
C+ G+ GPTC R C + C G+C G C C G+ G+ C + CPG C
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 771
Query: 695 RELCRAGQ----CVCVEGFRGPDCAI-------QTCPGDCRGRGECHDGSC 734
C Q CVC G+ G C + D G +C D C
Sbjct: 772 NGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC 822
Score = 195 bits (495), Expect = 9e-49
Identities = 96/269 (35%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
C +C G G C+ G C C PGF G DC CP C G+G E G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 557 ---RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWEGYV 612
+ C G G C+ G C+C GY GE C C + CS HG+C G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 613 SEDCS--IRTCPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCL 668
+C + C C G G + G C CDP +TG C+T +C +C G C +G+C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 669 CHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAI--------QTCP 720
C G+ G C + +C C C+ G+C C G+ G C I CP
Sbjct: 712 CEEGWVGPTCEER-----SCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCP 766
Query: 721 GDCRGRGEC----HDGSCVCKDGYAGEDC 745
G C G G C + CVC+ G++G C
Sbjct: 767 GLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 172 bits (437), Expect = 5e-42
Identities = 102/339 (30%), Positives = 134/339 (39%), Gaps = 51/339 (15%)
Query: 99 EVQALRVRLEILEELVKGLKE--QCTGG---CCPASAQAGTGQTDVRTLCSLHGVFDLSR 153
+V L +EI+++ +C G C P + LC +G ++
Sbjct: 518 QVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGH 577
Query: 154 CTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSC 213
C C GW GP C P + I P+ C G C+ G C+C PGY G C
Sbjct: 578 CVC--RHGWKGPECDVPEEQCIDPT------------CFGHGTCIMGVCICVPGYKGEIC 623
Query: 214 GWPSCPGD-CQGRGRCVQGVCVCRAGFSGPDCSQRS--CPRGCSQRGR--CEGGRCVCDP 268
C C G CV+G C C G+ G +C C CS G + G C CDP
Sbjct: 624 EEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDP 683
Query: 269 GYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVC 328
+TG DC C C G C G C C G+ G C RSC C++ G+CKDG+C C
Sbjct: 684 KWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCEC 743
Query: 329 DPGYTGEDCGTR--------SCPWDCGEGGRCV----DGRCVCWPGYTGEDCSTRTCPRD 376
PG+ G+ C CP C GRC CVC G++G C+
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVM---- 799
Query: 377 CRGRGRCEDGECICDTGYSGDDCGVRSC-PGDCNQRGRC 414
E +C D G+ C DC Q+ C
Sbjct: 800 ----------EMLCGDNLDNDGDGLTDCVDPDCCQQSNC 828
Score = 143 bits (361), Expect = 3e-33
Identities = 71/202 (35%), Positives = 93/202 (46%), Gaps = 14/202 (6%)
Query: 552 EDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGY 611
+DCST C G G+C+ G C C G+ G DC CP C +G + G C+C G+
Sbjct: 530 DDCSTN-----CNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGW 584
Query: 612 VSEDCSI---RTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC-PADCRGRGRCVQGVC 667
+C + + C G G C G C+C PGY G C C C G CV+G C
Sbjct: 585 KGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGEC 644
Query: 668 LCHVGYGGEDCGQEEPPASACPGGCGPRE--LCRAGQCVCVEGFRGPDCAIQTCPGDCRG 725
C G+GG +C E P C C L AG C C + G DC+ + C +C
Sbjct: 645 HCSTGWGGVNC---ETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGS 701
Query: 726 RGECHDGSCVCKDGYAGEDCGE 747
G C G C C++G+ G C E
Sbjct: 702 HGVCSRGICQCEEGWVGPTCEE 723
Score = 118 bits (295), Expect = 1e-25
Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Query: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649
C +C+ +G C G C C+ G++ DC+ +CP C G G E+G C+C G+ GP C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 650 ---RMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706
+ C G G C+ GVC+C GY GE C +E+ C +C G+C C
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEED----CLDPMCSNHGICVKGECHCS 647
Query: 707 EGFRGPDCA--IQTCPGDCRGRGE--CHDGSCVCKDGYAGEDCGEEVPTIE 753
G+ G +C + C C G G G C C + G DC E+ T+E
Sbjct: 648 TGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTME 698
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.136 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 215,154,755
Number of Sequences: 37866
Number of extensions: 13229134
Number of successful extensions: 74514
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 553
Number of HSP's that attempted gapping in prelim test: 42756
Number of HSP's gapped (non-prelim): 12629
length of query: 4242
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4119
effective length of database: 13,590,000
effective search space: 55977210000
effective search space used: 55977210000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.