Guide to the Human Genome
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Search of human proteins with 112807226

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112807226 hypothetical protein LOC91748 [Homo sapiens]
         (1045 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112807226 hypothetical protein LOC91748 [Homo sapiens]            2119   0.0  
gi|44890062 hypothetical protein LOC91748 [Homo sapiens]             2119   0.0  
gi|15812226 transcriptional regulating factor 1 [Homo sapiens]        328   2e-89
gi|210031154 zinc finger protein 541 [Homo sapiens]                   274   4e-73
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    65   3e-10
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    65   3e-10
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       62   3e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       62   3e-09
gi|171543895 ataxin 2 [Homo sapiens]                                   59   3e-08
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             58   4e-08
gi|55750053 atrophin-1 [Homo sapiens]                                  58   4e-08
gi|55750041 atrophin-1 [Homo sapiens]                                  58   4e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    57   7e-08
gi|7661892 REST corepressor 1 [Homo sapiens]                           57   9e-08
gi|56549696 E1A binding protein p400 [Homo sapiens]                    57   1e-07
gi|94721313 mesoderm induction early response 1, family member 3...    55   3e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          55   3e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          55   3e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          55   3e-07
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               55   3e-07
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    55   4e-07
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    55   4e-07
gi|91208420 bassoon protein [Homo sapiens]                             54   1e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     53   1e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     53   1e-06
gi|209977082 REST corepressor 3 isoform b [Homo sapiens]               53   2e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    52   2e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    52   3e-06
gi|209977084 REST corepressor 3 isoform c [Homo sapiens]               52   4e-06
gi|209977080 REST corepressor 3 isoform a [Homo sapiens]               52   4e-06

>gi|112807226 hypothetical protein LOC91748 [Homo sapiens]
          Length = 1045

 Score = 2119 bits (5491), Expect = 0.0
 Identities = 1045/1045 (100%), Positives = 1045/1045 (100%)

Query: 1    MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ 60
            MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ
Sbjct: 1    MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ 60

Query: 61   PVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS 120
            PVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS
Sbjct: 61   PVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS 120

Query: 121  WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR 180
            WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR
Sbjct: 121  WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR 180

Query: 181  PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV 240
            PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV
Sbjct: 181  PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV 240

Query: 241  AAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH 300
            AAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH
Sbjct: 241  AAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH 300

Query: 301  LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSAL 360
            LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSAL
Sbjct: 301  LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSAL 360

Query: 361  DGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNG 420
            DGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNG
Sbjct: 361  DGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNG 420

Query: 421  REREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQ 480
            REREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQ
Sbjct: 421  REREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQ 480

Query: 481  NAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTE 540
            NAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTE
Sbjct: 481  NAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTE 540

Query: 541  AAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKP 600
            AAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKP
Sbjct: 541  AAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKP 600

Query: 601  KQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPIL 660
            KQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPIL
Sbjct: 601  KQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPIL 660

Query: 661  SPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIE 720
            SPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIE
Sbjct: 661  SPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIE 720

Query: 721  PRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSI 780
            PRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSI
Sbjct: 721  PRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSI 780

Query: 781  FPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKL 840
            FPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKL
Sbjct: 781  FPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKL 840

Query: 841  FNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQ 900
            FNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQ
Sbjct: 841  FNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQ 900

Query: 901  EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRE 960
            EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRE
Sbjct: 901  EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRE 960

Query: 961  RSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSE 1020
            RSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSE
Sbjct: 961  RSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSE 1020

Query: 1021 KKKKTETFSKTQNQENTFPCKKCGR 1045
            KKKKTETFSKTQNQENTFPCKKCGR
Sbjct: 1021 KKKKTETFSKTQNQENTFPCKKCGR 1045


>gi|44890062 hypothetical protein LOC91748 [Homo sapiens]
          Length = 1045

 Score = 2119 bits (5491), Expect = 0.0
 Identities = 1045/1045 (100%), Positives = 1045/1045 (100%)

Query: 1    MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ 60
            MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ
Sbjct: 1    MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ 60

Query: 61   PVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS 120
            PVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS
Sbjct: 61   PVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS 120

Query: 121  WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR 180
            WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR
Sbjct: 121  WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR 180

Query: 181  PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV 240
            PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV
Sbjct: 181  PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV 240

Query: 241  AAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH 300
            AAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH
Sbjct: 241  AAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH 300

Query: 301  LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSAL 360
            LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSAL
Sbjct: 301  LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSAL 360

Query: 361  DGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNG 420
            DGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNG
Sbjct: 361  DGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNG 420

Query: 421  REREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQ 480
            REREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQ
Sbjct: 421  REREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQ 480

Query: 481  NAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTE 540
            NAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTE
Sbjct: 481  NAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTE 540

Query: 541  AAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKP 600
            AAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKP
Sbjct: 541  AAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKP 600

Query: 601  KQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPIL 660
            KQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPIL
Sbjct: 601  KQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPIL 660

Query: 661  SPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIE 720
            SPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIE
Sbjct: 661  SPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIE 720

Query: 721  PRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSI 780
            PRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSI
Sbjct: 721  PRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSI 780

Query: 781  FPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKL 840
            FPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKL
Sbjct: 781  FPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKL 840

Query: 841  FNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQ 900
            FNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQ
Sbjct: 841  FNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQ 900

Query: 901  EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRE 960
            EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRE
Sbjct: 901  EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRE 960

Query: 961  RSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSE 1020
            RSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSE
Sbjct: 961  RSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSE 1020

Query: 1021 KKKKTETFSKTQNQENTFPCKKCGR 1045
            KKKKTETFSKTQNQENTFPCKKCGR
Sbjct: 1021 KKKKTETFSKTQNQENTFPCKKCGR 1045


>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
          Length = 1200

 Score =  328 bits (841), Expect = 2e-89
 Identities = 302/978 (30%), Positives = 426/978 (43%), Gaps = 134/978 (13%)

Query: 119  SSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRY 178
            S +QQ P QP P  T      +L    +   HP  G   YY++ + L +           
Sbjct: 199  SRYQQVPQQPHPGFTGGLSKPAL----QVGQHPTQG-HLYYDYQQPLAQ----------- 242

Query: 179  VRPMMPQKVQLEVGRP-QAP-LNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPP 236
                    V ++ G+P QAP + S H  +   +Q  P Q  Q A   +++ Q  +  P  
Sbjct: 243  --------VPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294

Query: 237  PNPVAAFPPQKQQQQQQPQQQQQQQQAALPQ----MPLFENFYSMPQQ------PS--QQ 284
              P    PP +QQQ QQ Q QQ+Q    +PQ     P+ ++     QQ      PS  + 
Sbjct: 295  IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD 354

Query: 285  PQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPR 344
            P  +  + A  +    L   S   Y  P  P  +P  +++ L     +           R
Sbjct: 355  PHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDR 414

Query: 345  RSRR-LSKEGILPPSALDGAGTQPGQEATG-NLFLHHWPLQQPPPGSLGQPHPEALGF-P 401
            +++  LS  G L P    G G     + T  +  L H PL  P    L    P+     P
Sbjct: 415  QAQAMLSSHGDLGPPDT-GMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSP 473

Query: 402  LELRESQLLPDGERLAPNGREREAPAMGS-EEGMRAVSTGDCGQVLRGGVIQSTRRRRRA 460
              +     LPDG R  P   E      G+  E   A +   C   L+             
Sbjct: 474  SAMWPQMHLPDG-RAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLK------------- 519

Query: 461  SQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDS 520
              E   L      +       A      EE  K +             P    +   E  
Sbjct: 520  --EFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAE 577

Query: 521  GMVPLIIPVSVPVRTVDPTEAAQAGGLDEDGKGPE--QNPA-----EHKPSVIVTRRRST 573
             + P+++PVSVPV+ + P  ++Q G  +     P     PA     +  P + + R+   
Sbjct: 578  SLTPMVMPVSVPVKLLPPKPSSQ-GFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQP 636

Query: 574  RIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPV-YSNITPYQS 632
             +P  +   +               K K R RPEPL IP        P   YS  T YQS
Sbjct: 637  SVPKAEEPLKTVQ-----------EKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQS 685

Query: 633  HLRSPVRLADHPS-ERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPP--PITPK 689
             LRSP  L DH   + + ELPPYTPPP+LSPVR+GSGL+ N +IS     A P  P+TP 
Sbjct: 686  QLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPL 745

Query: 690  SAHRTLLRTNSAEVTPPVLSVM---GEATPVSIEPRINVGSRFQAEIPLMRDRALAAADP 746
            +    +L   S  +    ++V    GE T V +EPRIN+G RFQAEIP ++D +  A D 
Sbjct: 746  TPTPRVLLCRSNSIDGSNVTVTPGPGEQT-VDVEPRINIGLRFQAEIPELQDISALAQDT 804

Query: 747  HKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETL 806
            HKA LVW+PW +LE+  + Q++VE+LL   CSS  PG GTN E ALH L E++GD++  L
Sbjct: 805  HKATLVWKPWPELEN-HDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL 863

Query: 807  NKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQ 866
              LLL+KP+R   HPLA YHY GSD+W   ERKLFNK +A Y KDF  VQK++++KTVAQ
Sbjct: 864  EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ 923

Query: 867  CVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSE 926
            CVE+YYT+KK +++GR       ++   D  +++EE E++                   E
Sbjct: 924  CVEYYYTWKKIMRLGRKHRTRLAEI-IDDCVTSEEEEELE-------------------E 963

Query: 927  ERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQANESASDILIL 986
            E  E   E ++  KE E EVP+  E               A      LQA    S   I 
Sbjct: 964  EEEEDPEEDRKSTKEEESEVPKSPEPPPVP--------VLAPTEGPPLQALGQPSGSFIC 1015

Query: 987  RSHESNAPGSAGGQASEKPREGTG-----KSRRALPFSEKK-----------KKTETFSK 1030
                  A  S+    +   R   G     K+R A+P  ++K           K + + S 
Sbjct: 1016 EMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHST 1075

Query: 1031 TQNQEN---TFPCKKCGR 1045
            T  + +    FPCK+CG+
Sbjct: 1076 TSGETDPTTIFPCKECGK 1093


>gi|210031154 zinc finger protein 541 [Homo sapiens]
          Length = 1365

 Score =  274 bits (700), Expect = 4e-73
 Identities = 179/462 (38%), Positives = 240/462 (51%), Gaps = 74/462 (16%)

Query: 513  TKRAREDSGMVPLIIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRS 572
            TK+  + +   PL++P S+PV  V                        H  S+ +    S
Sbjct: 900  TKKPLDPTAAAPLVVPQSIPVVPV----------------------TRHIGSMAMMEWCS 937

Query: 573  TRIPGTDA-----QAQAEDMNVKLEGEPSV-RKPKQRPRPEPLIIPTKAGTFIAPPVYSN 626
              +  T       Q Q +D   +   E S  RK K+RP P     P  AG          
Sbjct: 938  RWLQATTCGSKLLQGQEKDGEERDSKESSQQRKRKKRPPPSTAGEPGPAGC--------- 988

Query: 627  ITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPPPI 686
               +QS LRSP+ L D   +  F+  PYTPPP+LSP+REGSG+YFN + STST  +P   
Sbjct: 989  ---HQSRLRSPMFLVDCLLKGLFQCSPYTPPPMLSPIREGSGVYFNTLCSTSTQASPDQ- 1044

Query: 687  TPKSAHRTLLRTNSAEVTPPV-LSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAAD 745
                    L+ +   +V     + V+ + T +SIEP IN+GSRFQAEIP +++R+LA  D
Sbjct: 1045 --------LISSMLDQVDGSFGICVVKDDTKISIEPHINIGSRFQAEIPELQERSLAGTD 1096

Query: 746  PHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILET 805
             H A LVW+PW D+  S E Q +V +L   ACSS+ PG GTN ELALHCLHE++G++   
Sbjct: 1097 EHVASLVWKPWGDMMISSETQDRVTELCNVACSSVMPGGGTNLELALHCLHEAQGNVQVA 1156

Query: 806  LNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVA 865
            L  LLL+ P +P  H LA Y YTGSD W   E++LF K    +KKDF+L+ K+IQTKTVA
Sbjct: 1157 LETLLLRGPHKPRTHLLADYRYTGSDVWTPIEKRLFKKAFYAHKKDFYLIHKMIQTKTVA 1216

Query: 866  QCVEFYYTYKKQVKI--GRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRES 923
            QCVE+YY +KK +K   GR   L         EK  + E E   +T +K P  P   RE 
Sbjct: 1217 QCVEYYYIWKKMIKFDCGRAPGL---------EKRVKREPEEVERTEEKVPCSP---RER 1264

Query: 924  PSEERLEPKREVKEPRKE---------GEEEVPEIQEKEEQE 956
            PS     PK + K  R+E         G +  PE+    E +
Sbjct: 1265 PSHHP-TPKLKTKSYRRESILSSSPNAGSKRTPELLGSAESQ 1305


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 78/262 (29%), Positives = 100/262 (38%), Gaps = 52/262 (19%)

Query: 125 PGQPPPHSTWNCHSLSLYSATKGSPHPG-VGVPTYYNHPEALKREKAGGPQLDRYVRPMM 183
           PG  PP S  + HS    S     PHP  +G P + + P +      GGP       P M
Sbjct: 104 PGMGPPQSPMDQHSQGYMS-----PHPSPLGAPEHVSSPMS-----GGGP-----TPPQM 148

Query: 184 P--QKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFR-----QGPPP 236
           P  Q   L  G PQA         +P     P  P QL   HQ+  Q+       +G P 
Sbjct: 149 PPSQPGALIPGDPQA-------MSQPNRGPSPFSPVQL---HQLRAQILAYKMLARGQPL 198

Query: 237 PNPVAAF-----------PPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPS--- 282
           P  +                Q+QQQQQQ QQQQQQQQ   PQ    +      QQP+   
Sbjct: 199 PETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVN 258

Query: 283 -QQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPA--LPQVQ 339
             +P   G + +GP     L   +    P P  P        A+   S PQPA   P   
Sbjct: 259 YNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPV 318

Query: 340 IPFPRRSRRLSKEGILPPSALD 361
           +   ++  R+S   I  P  LD
Sbjct: 319 LQLQQKQSRISP--IQKPQGLD 338


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 78/262 (29%), Positives = 100/262 (38%), Gaps = 52/262 (19%)

Query: 125 PGQPPPHSTWNCHSLSLYSATKGSPHPG-VGVPTYYNHPEALKREKAGGPQLDRYVRPMM 183
           PG  PP S  + HS    S     PHP  +G P + + P +      GGP       P M
Sbjct: 104 PGMGPPQSPMDQHSQGYMS-----PHPSPLGAPEHVSSPMS-----GGGP-----TPPQM 148

Query: 184 P--QKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFR-----QGPPP 236
           P  Q   L  G PQA         +P     P  P QL   HQ+  Q+       +G P 
Sbjct: 149 PPSQPGALIPGDPQA-------MSQPNRGPSPFSPVQL---HQLRAQILAYKMLARGQPL 198

Query: 237 PNPVAAF-----------PPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPS--- 282
           P  +                Q+QQQQQQ QQQQQQQQ   PQ    +      QQP+   
Sbjct: 199 PETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVN 258

Query: 283 -QQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPA--LPQVQ 339
             +P   G + +GP     L   +    P P  P        A+   S PQPA   P   
Sbjct: 259 YNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPV 318

Query: 340 IPFPRRSRRLSKEGILPPSALD 361
           +   ++  R+S   I  P  LD
Sbjct: 319 LQLQQKQSRISP--IQKPQGLD 338


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 65/240 (27%), Positives = 92/240 (38%), Gaps = 13/240 (5%)

Query: 104 PGRGPERGGGGGVSDSSWQQQ---PGQPPPHSTWNC-HSLSLYSATKGSPHPGVGVPTYY 159
           P RGP +  GG  S  +  Q     GQPPP ++    HS+++ S         +      
Sbjct: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQ 161

Query: 160 NHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQL 219
              +  + ++     L +  +    Q+ Q +    Q    +    ++   Q    Q   +
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221

Query: 220 AFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQ 279
              HQ N+Q  +Q       +A    Q QQQQQQ QQQQQQQQA   Q P+ +     PQ
Sbjct: 222 KLHHQ-NQQQIQQQQQQLQRIAQLQLQ-QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279

Query: 280 QPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQ 339
            P  Q     LQ        H  HH   P P P  P +       L   S  QP + Q Q
Sbjct: 280 PPPSQALPQQLQQ-----MHHTQHHQ--PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQ 332



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 83/349 (23%), Positives = 121/349 (34%), Gaps = 51/349 (14%)

Query: 185 QKVQLEVGRPQAPLNS--FHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAA 242
           Q+ Q +  + Q P+        + PP+Q+LP Q  Q+   H  + Q      PPP P   
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH--HTQHHQ------PPPQPQQ- 307

Query: 243 FPPQKQQQQQQ-PQQQQQQ----QQAALPQMPLFE----NFYSMP---QQPSQQPQDFGL 290
            PP  Q Q  Q P Q Q Q    Q  ALP   L+      F   P   QQP  QPQ    
Sbjct: 308 -PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ 366

Query: 291 QPAGPLGQSHLAHHSMAPYPFPPNPDMNPELR-------KALLQDSAPQPALPQVQIPFP 343
           Q A    Q        A     P   M  E         +A    +    A+P   IP  
Sbjct: 367 QTAVQTAQ--------AAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLG 418

Query: 344 RRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGS-LGQPHPEALGFPL 402
           R+      +  LP      +   PGQ+      +   P   P PG    QP+      P 
Sbjct: 419 RQPMAQVSQSSLPML----SSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA 474

Query: 403 ELRESQLLPDGERLAPNGREREAPAMG-SEEGMRAVSTGDCGQVLRGGVIQSTRRRRRAS 461
               S  LP     +P+ +  ++P    + +     S G     +    + S     +A 
Sbjct: 475 P-SPSSFLP-----SPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAE 528

Query: 462 QEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPS 510
           ++  L  L Q +  +  L+   +     E RK  L+         ++PS
Sbjct: 529 EQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPS 577


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 65/240 (27%), Positives = 92/240 (38%), Gaps = 13/240 (5%)

Query: 104 PGRGPERGGGGGVSDSSWQQQ---PGQPPPHSTWNC-HSLSLYSATKGSPHPGVGVPTYY 159
           P RGP +  GG  S  +  Q     GQPPP ++    HS+++ S         +      
Sbjct: 102 PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQ 161

Query: 160 NHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQL 219
              +  + ++     L +  +    Q+ Q +    Q    +    ++   Q    Q   +
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221

Query: 220 AFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQ 279
              HQ N+Q  +Q       +A    Q QQQQQQ QQQQQQQQA   Q P+ +     PQ
Sbjct: 222 KLHHQ-NQQQIQQQQQQLQRIAQLQLQ-QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279

Query: 280 QPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQ 339
            P  Q     LQ        H  HH   P P P  P +       L   S  QP + Q Q
Sbjct: 280 PPPSQALPQQLQQ-----MHHTQHHQ--PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQ 332



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 64/238 (26%), Positives = 88/238 (36%), Gaps = 41/238 (17%)

Query: 185 QKVQLEVGRPQAPLNS--FHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAA 242
           Q+ Q +  + Q P+        + PP+Q+LP Q  Q+   H  + Q      PPP P   
Sbjct: 257 QQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH--HTQHHQ------PPPQPQQ- 307

Query: 243 FPPQKQQQQQQ-PQQQQQQ----QQAALPQMPLFE----NFYSMP---QQPSQQPQDFGL 290
            PP  Q Q  Q P Q Q Q    Q  ALP   L+      F   P   QQP  QPQ    
Sbjct: 308 -PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ 366

Query: 291 QPAGPLGQSHL-----AHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRR 345
           Q A    Q+          S +  P   +P    +++        PQP+ PQ   P  + 
Sbjct: 367 QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS-PQPGQPSSQP 425

Query: 346 SRRLSKEGILPPSA-LDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPL 402
           +  +S      PS+ L     QP Q           P+    P +   P P  L  P+
Sbjct: 426 NSNVSSGPAPSPSSFLPSPSPQPSQS----------PVTARTPQNFSVPSPGPLNTPV 473



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 64/288 (22%), Positives = 108/288 (37%), Gaps = 43/288 (14%)

Query: 1   MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQ----PPQQSI--RVKEEQYLGHEGP-- 52
           + LQ Q + Q ++++      +  P  Q PP+Q    PP Q++  ++++  +  H  P  
Sbjct: 244 LQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP 303

Query: 53  ---GGAVSTSQPVELPPPSSLALLNSVVYGPERTSAAMLSQQ--VASVKWPNSVMAPGRG 107
                 V+ +QP +LPP S       +V   +     ML  Q  +  V+ P  V  P   
Sbjct: 304 QPQQPPVAQNQPSQLPPQSQ---TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360

Query: 108 P---ERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEA 164
           P   ++      + ++    PG     S     SL + S    SP PG  V T    P++
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGVQVSQS-----SLPMLS----SPSPGQQVQT----PQS 407

Query: 165 LKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQ 224
           +       PQ     +P       +  G   +P +   +    P+QS       +     
Sbjct: 408 MPPPPQPSPQPG---QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS------PVTARTP 458

Query: 225 VNRQVFRQGP--PPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPL 270
            N  V   GP   P NP +   P    Q ++ Q   + +Q +    PL
Sbjct: 459 QNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPL 506


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 74/258 (28%), Positives = 93/258 (36%), Gaps = 64/258 (24%)

Query: 73  LNSVVYGPERTSAAMLSQQVASVKWPN--SVMAPGRGPERGGGG---GVSDSSWQQQPGQ 127
           + S    P   + A  S++ A+ +WP   S+  P R   RGGGG   G   S+    PG 
Sbjct: 1   MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGP 60

Query: 128 PPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKV 187
            PP S  +  S    S   GS   G G       P + +    GGP      RP +   +
Sbjct: 61  GPPPSRQS--SPPSASDCFGSNGNGGGA----FRPGSRRLLGLGGPP-----RPFVV--L 107

Query: 188 QLEVGRPQAP------LNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVA 241
            L +  P AP       +   A   PP   + L                R  P  P P  
Sbjct: 108 LLPLASPGAPPAAPTRASPLGARASPPRSGVSLA---------------RPAPGCPRPAC 152

Query: 242 ---------AFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQP 292
                    +  PQ+QQQQQQ QQQQQQQQ                QQ  QQP       
Sbjct: 153 EPVYGPLTMSLKPQQQQQQQQQQQQQQQQQ----------------QQQQQQPPPAAANV 196

Query: 293 AGPLGQSHLAHHSMAPYP 310
             P G   LA  + AP P
Sbjct: 197 RKPGGSGLLASPAAAPSP 214



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 13/86 (15%)

Query: 1   MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQ 60
           M+L+ Q + Q ++++     Q+   ++Q    QPP  +  V++        PGG+   + 
Sbjct: 161 MSLKPQQQQQQQQQQ-----QQQQQQQQQQQQQPPPAAANVRK--------PGGSGLLAS 207

Query: 61  PVELPPPSSLALLNSVVYGPERTSAA 86
           P   P PSS ++ +S    P    AA
Sbjct: 208 PAAAPSPSSSSVSSSSATAPSSVVAA 233



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 31/153 (20%), Positives = 56/153 (36%), Gaps = 20/153 (13%)

Query: 555  EQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTK 614
            E++  E K       R+ST  P       A++ N +   +P        PRP+    P+ 
Sbjct: 895  EKDDKEEKKDAAEQVRKSTLNPN------AKEFNPRSFSQPKPSTTPTSPRPQAQPSPSM 948

Query: 615  AGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAI 674
             G     PVY+    +  ++  PV ++  P  +     P TP P+            N  
Sbjct: 949  VGHQQPTPVYTQPVCFAPNMMYPVPVS--PGVQPLYPIPMTPMPV------------NQA 994

Query: 675  ISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPV 707
             +   +P  P       H++ +   ++   PP+
Sbjct: 995  KTYRAVPNMPQQRQDQHHQSAMMHPASAAGPPI 1027


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 9/175 (5%)

Query: 833  WKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVD 892
            W   E+++F      + K+F L+   ++ K+V  CV +YY  KK           +G   
Sbjct: 440  WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRR 499

Query: 893  TSDEKSAQ--EEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQ 950
              +++ A+  +E +V+ K   K  +      E   EE  + K + KE  KE ++     +
Sbjct: 500  GRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAE 559

Query: 951  EKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKP 1005
            E EE+E+   R R+ A  +  +  +   S        ++E+ A  +A   A+E+P
Sbjct: 560  ETEEREQATPRGRKTANSQGRRKGRITRS-------MTNEAAAASAAAAAATEEP 607



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/182 (24%), Positives = 76/182 (41%), Gaps = 27/182 (14%)

Query: 814 PLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYT 873
           PL P   P++T     S +W   E ++  KG+  + +++  + K++ TK+ AQC  FY+ 
Sbjct: 610 PLPPPPEPISTEPVETS-RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFN 668

Query: 874 YKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKR 933
           YK++            ++D   ++  Q       KTS+K PR      +  S       +
Sbjct: 669 YKRR-----------HNLDNLLQQHKQ-------KTSRK-PREERDVSQCESVASTVSAQ 709

Query: 934 EVKEPRKEGEEEVPEIQE-------KEEQEEGRERSRRAAAVKATQTLQANESASDILIL 986
           E ++     EEE PE  E       ++  E    R     AV+   T +   S S  L +
Sbjct: 710 EDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAV 769

Query: 987 RS 988
            S
Sbjct: 770 PS 771



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 5/71 (7%)

Query: 927 ERLE--PKREVKEP--RKEGEEEVPEIQEKEEQEEGRER-SRRAAAVKATQTLQANESAS 981
           +R+E  P+R+ KE   R+  E++ PEI+++ EQ+E  +R  +R A + AT     +E + 
Sbjct: 323 DRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISE 382

Query: 982 DILILRSHESN 992
            I  L   E+N
Sbjct: 383 IIDGLSEQENN 393


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 89/354 (25%), Positives = 116/354 (32%), Gaps = 113/354 (31%)

Query: 19  GGQEPAPKEQP-----------PPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVE---- 63
           GG++  P   P           PP +PP   +           G G   S   P      
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPV-----------GGGNLPSAPPPANFPHV 297

Query: 64  ---LPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS 120
              LPPP +L  LN+    P    A  L   + S        A G+G      GG+    
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH------AMGQGM-----GGLPPGP 346

Query: 121 WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR 180
            +     P PHS        L  A+  +P P +  P Y +   +     +          
Sbjct: 347 EKGPTLAPSPHS--------LPPASSSAPAPPMRFP-YSSSSSSSAAASSSSSSSSSSAS 397

Query: 181 PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV 240
           P    +          P  S   + +PP  + P  P Q          V+ QGPPPP P 
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQA---------VWSQGPPPPPPY 448

Query: 241 AA-----------FPP--------------------QKQQQQQQPQQQQQQQQAALPQMP 269
                        FPP                    Q+QQQQQQ QQQQQQQQ       
Sbjct: 449 GRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQ------ 502

Query: 270 LFENFYSMPQQPSQQPQDFGLQPAGPL--GQSHLAH-HSMAP-----YPFPPNP 315
              +  S P  P   P         PL  G SH AH ++M+P      P+PP P
Sbjct: 503 --HHGNSGPPPPGAFPH--------PLEGGSSHHAHPYAMSPSLGSLRPYPPGP 546



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 69/304 (22%), Positives = 117/304 (38%), Gaps = 58/304 (19%)

Query: 419 NGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELAS 478
           +GR++EAP  G  E +R+      G+   GGV  S+   +    E +  T  +  VE AS
Sbjct: 14  SGRKKEAP--GPREELRSR-----GRASPGGVSTSSSDGKA---EKSRQTAKKARVEEAS 63

Query: 479 LQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDP 538
                    SEE  +S    T       +E  L   ++  D          S+  R+++ 
Sbjct: 64  TPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--------SLDGRSLND 115

Query: 539 TEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVR 598
             ++    +D+D +    +P+ + P  +     S+      +Q  A   +      PS +
Sbjct: 116 DGSSDPRDIDQDNRST--SPSIYSPGSVENDSDSS---SGLSQGPARPYHPPPLFPPSPQ 170

Query: 599 KPKQRPR-PEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPP 657
            P   PR PE    P           + ++TP   H  +P+   + P+ R F+ PP  PP
Sbjct: 171 PPDSTPRQPEASFEP-----------HPSVTPTGYH--APM---EPPTSRMFQAPPGAPP 214

Query: 658 PILSPVREGSGLYFNAIISTSTIPAPPPITPK--SAHRTLLRTNSAEVTPPVLSVMGEAT 715
           P       G+G           + + PP+ PK   A  ++   N  +  PP        T
Sbjct: 215 PHPQLYPGGTG----------GVLSGPPMGPKGGGAASSVGGPNGGKQHPP------PTT 258

Query: 716 PVSI 719
           P+S+
Sbjct: 259 PISV 262


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 89/354 (25%), Positives = 116/354 (32%), Gaps = 113/354 (31%)

Query: 19  GGQEPAPKEQP-----------PPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVE---- 63
           GG++  P   P           PP +PP   +           G G   S   P      
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPV-----------GGGNLPSAPPPANFPHV 297

Query: 64  ---LPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSS 120
              LPPP +L  LN+    P    A  L   + S        A G+G      GG+    
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH------AMGQGM-----GGLPPGP 346

Query: 121 WQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVR 180
            +     P PHS        L  A+  +P P +  P Y +   +     +          
Sbjct: 347 EKGPTLAPSPHS--------LPPASSSAPAPPMRFP-YSSSSSSSAAASSSSSSSSSSAS 397

Query: 181 PMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPV 240
           P    +          P  S   + +PP  + P  P Q          V+ QGPPPP P 
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQA---------VWSQGPPPPPPY 448

Query: 241 AA-----------FPP--------------------QKQQQQQQPQQQQQQQQAALPQMP 269
                        FPP                    Q+QQQQQQ QQQQQQQQ       
Sbjct: 449 GRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQ------ 502

Query: 270 LFENFYSMPQQPSQQPQDFGLQPAGPL--GQSHLAH-HSMAP-----YPFPPNP 315
              +  S P  P   P         PL  G SH AH ++M+P      P+PP P
Sbjct: 503 --HHGNSGPPPPGAFPH--------PLEGGSSHHAHPYAMSPSLGSLRPYPPGP 546



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 69/304 (22%), Positives = 117/304 (38%), Gaps = 58/304 (19%)

Query: 419 NGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELAS 478
           +GR++EAP  G  E +R+      G+   GGV  S+   +    E +  T  +  VE AS
Sbjct: 14  SGRKKEAP--GPREELRSR-----GRASPGGVSTSSSDGKA---EKSRQTAKKARVEEAS 63

Query: 479 LQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDP 538
                    SEE  +S    T       +E  L   ++  D          S+  R+++ 
Sbjct: 64  TPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--------SLDGRSLND 115

Query: 539 TEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVR 598
             ++    +D+D +    +P+ + P  +     S+      +Q  A   +      PS +
Sbjct: 116 DGSSDPRDIDQDNRST--SPSIYSPGSVENDSDSS---SGLSQGPARPYHPPPLFPPSPQ 170

Query: 599 KPKQRPR-PEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPP 657
            P   PR PE    P           + ++TP   H  +P+   + P+ R F+ PP  PP
Sbjct: 171 PPDSTPRQPEASFEP-----------HPSVTPTGYH--APM---EPPTSRMFQAPPGAPP 214

Query: 658 PILSPVREGSGLYFNAIISTSTIPAPPPITPK--SAHRTLLRTNSAEVTPPVLSVMGEAT 715
           P       G+G           + + PP+ PK   A  ++   N  +  PP        T
Sbjct: 215 PHPQLYPGGTG----------GVLSGPPMGPKGGGAASSVGGPNGGKQHPP------PTT 258

Query: 716 PVSI 719
           P+S+
Sbjct: 259 PISV 262


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 90/346 (26%), Positives = 112/346 (32%), Gaps = 93/346 (26%)

Query: 21   QEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGP 80
            Q P P +QPPP  PPQQ                      QP   PPP S+         P
Sbjct: 756  QPPPPPQQPPPPPPPQQQ--------------------QQPPPPPPPPSM---------P 786

Query: 81   ERTSAAMLSQ---------QVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQP------ 125
            ++ + AM S           V   + P SV  P        G          QP      
Sbjct: 787  QQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDP-------IGHFTQPILHLPQPELPPHL 839

Query: 126  GQPPPHST---WNCHSL----SLYSATKGSP----HPGVGVPTYYNHPEALKREKAGGPQ 174
             QPP HST    N H++    +L++A    P    +    +P     P A+       P 
Sbjct: 840  PQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPL 899

Query: 175  LDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGP 234
            L +      PQ +  +   P  PL S               P  L    +V  Q     P
Sbjct: 900  LPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ-----P 954

Query: 235  PPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGL---Q 291
            PPP P    P  +QQ QQQP      Q    PQ P  +     P+    QP  F     Q
Sbjct: 955  PPPLPPPPHPSVQQQLQQQPPPPPPPQ----PQPPPQQQHQPPPRPVHLQPMQFSTHIQQ 1010

Query: 292  PAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQ 337
            P  P GQ             PP+P           Q   PQPA PQ
Sbjct: 1011 PPPPQGQQ------------PPHPPPGQ-------QPPPPQPAKPQ 1037



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 62/215 (28%), Positives = 82/215 (38%), Gaps = 20/215 (9%)

Query: 224 QVNRQVFRQGPPPPN-PVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPS 282
           Q    V +Q PPPP  P    PPQ+QQQ   P       Q A P M      +   Q P 
Sbjct: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807

Query: 283 QQPQDFG--LQPAGPLGQS--HLAHHSMAPY-PFPPNPDMNPELRK-ALLQDSAPQPALP 336
            +PQ  G    P G   Q   HL    + P+ P PP     P L + A++   A   ALP
Sbjct: 808 LEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALP 867

Query: 337 QVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPE 396
           Q      + SR  ++   LPP         P    T    L   P+ QPP   L    P 
Sbjct: 868 Q------QPSRPSNRAAALPPKPARPPAVSPA--LTQTPLLPQPPMAQPPQVLLEDEEPP 919

Query: 397 A-----LGFPLELRESQLLPDGERLAPNGREREAP 426
           A     +   L L++ Q +     L P+ + +  P
Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP 954



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 80/287 (27%), Positives = 109/287 (37%), Gaps = 38/287 (13%)

Query: 122  QQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRP 181
            QQQP  PPP  +    +     A K SP P +        P+      +    +  + +P
Sbjct: 773  QQQPPPPPPPPSMPQQAAP---AMKSSPPPFIATQVPVLEPQL---PGSVFDPIGHFTQP 826

Query: 182  MM--PQKVQLEVGRPQAPLNSF------HAAKKPP--NQSLPLQPFQLAFGHQVNRQVFR 231
            ++  PQ  +L    PQ P +S       HA   PP  + +LP QP         +R   R
Sbjct: 827  ILHLPQP-ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQP---------SRPSNR 876

Query: 232  QGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDF--- 288
                PP P  A PP       Q     Q   A  PQ+ L +     P   S Q Q +   
Sbjct: 877  AAALPPKP--ARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ 934

Query: 289  --GLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRS 346
               +QP  PL  S +   S  P P PP P  +P +++ L Q   P P  PQ Q P  ++ 
Sbjct: 935  LQKVQPPTPLLPS-VKVQSQPPPPLPPPP--HPSVQQQLQQQPPPPPP-PQPQPPPQQQH 990

Query: 347  RRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQP 393
            +   +   L P        QP     G    H  P QQPPP    +P
Sbjct: 991  QPPPRPVHLQPMQFSTHIQQP-PPPQGQQPPHPPPGQQPPPPQPAKP 1036



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 58/245 (23%), Positives = 84/245 (34%), Gaps = 49/245 (20%)

Query: 23   PAPKEQPPPLQ---PPQQSIRVKEEQYLGH-----EGPGGAVSTSQPVELPPPSSLALLN 74
            P P+ QPPP Q   PP + + ++  Q+  H        G       P + PPP   A   
Sbjct: 978  PPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037

Query: 75   SVV---YGPERTSAAMLSQ-QVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPP 130
             V+   + P    +   S   +     P  + +P              S +Q    Q PP
Sbjct: 1038 QVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQM------------SQFQSLTHQSPP 1085

Query: 131  HSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLE 190
                      L +A+   P P V V     H   ++ E    P L R   P  P+ ++  
Sbjct: 1086 QQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFS-PSL-RPEPPKHPESIKAP 1143

Query: 191  VGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQ 250
            V  PQ P        KP +               V R V R  PP  N      P K +Q
Sbjct: 1144 VHLPQRP------EMKPVD---------------VGRPVIR--PPEQNAPPPGAPDKDKQ 1180

Query: 251  QQQPQ 255
            +Q+P+
Sbjct: 1181 KQEPK 1185



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 21/41 (51%), Positives = 25/41 (60%), Gaps = 6/41 (14%)

Query: 246  QKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQ 286
            ++QQQQ+Q QQQQQQQQAA           + PQ  S QPQ
Sbjct: 1284 EQQQQQRQEQQQQQQQQAAAVAAA------ATPQAQSSQPQ 1318



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 6/95 (6%)

Query: 896  EKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQ 955
            EK+ + + E   K  ++  +  +  RE   E+ LE  R   E  +  +E+    Q+++ Q
Sbjct: 1238 EKALKAQAEHAEKEKERLRQERMRSRED--EDALEQARRAHEEARRRQEQ----QQQQRQ 1291

Query: 956  EEGRERSRRAAAVKATQTLQANESASDILILRSHE 990
            E+ +++ ++AAAV A  T QA  S    ++ +  E
Sbjct: 1292 EQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326


>gi|7661892 REST corepressor 1 [Homo sapiens]
          Length = 482

 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 55/245 (22%), Positives = 111/245 (45%), Gaps = 41/245 (16%)

Query: 723 INVGSRFQAEIPLMRDRALAAADPHKADL---VWQPWEDLESSREKQRQVEDLLTAACSS 779
           + VG ++QA +P      LA     + +L   VW P ++L  ++     +++ +  A   
Sbjct: 102 MRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAK-----LDEYIAIAKEK 156

Query: 780 IFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERK 839
                G N E AL  L   + +I ++L  L       P+  P         D+W + ++ 
Sbjct: 157 ----HGYNMEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKV 198

Query: 840 LFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSA 899
           LF +  + + K F  +Q+++  K++A  V+FYY++KK     R  T    D     +K  
Sbjct: 199 LFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKT----RTKTSVM-DRHARKQKRE 253

Query: 900 QEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGR 959
           +EE E +++ +     + +       ++  E K+EV        E VP++++++   + +
Sbjct: 254 REESEDELEEANGNNPIDI-----EVDQNKESKKEVPP-----TETVPQVKKEKHSTQAK 303

Query: 960 ERSRR 964
            R++R
Sbjct: 304 NRAKR 308



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 832 QWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDV 891
           +W   E+ L  + I  Y +DF  +  +I  K+V Q   F+  Y+++  I  +  L   + 
Sbjct: 382 RWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNI--DEVLQEWEA 439

Query: 892 DTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESP 924
           +   E++     +  +K+     ++P    E+P
Sbjct: 440 EHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAP 472


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 86/335 (25%), Positives = 115/335 (34%), Gaps = 30/335 (8%)

Query: 21   QEPAPKEQPPPLQPPQQSIR-VKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYG 79
            Q P P+ QPPP  PPQQ    + + Q  G + P G  +  QP   P P +       V  
Sbjct: 2505 QPPPPQPQPPP--PPQQPPPPLPQPQAAGSQPPAGPPAV-QPQPQPQPQTQP---QPVQA 2558

Query: 80   PERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSL 139
            P +   A+ +   A+V    ++     G     G    +       G P          L
Sbjct: 2559 PAKAQPAITTGGSAAVL-AGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRL 2617

Query: 140  SLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLN 199
            +   A      PG   P    H +   R   G P          P  V +   +    + 
Sbjct: 2618 ASPVAPGALTTPGGSAPAQVVHTQPPPRA-VGSPAT------ATPDLVSMATTQGVRAVT 2670

Query: 200  SFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFP--------PQKQQQQ 251
            S  A+        P+Q    +   QV++    Q P      A F          Q+QQQQ
Sbjct: 2671 SVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQ 2730

Query: 252  QQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHH-----SM 306
            QQ QQQQQQQQ    Q     +   +PQ   Q      ++  G L   HL         M
Sbjct: 2731 QQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQM 2790

Query: 307  APYPFPPNPDMNPELRKALLQDSAPQPALPQVQIP 341
             P P PP     P    A +Q    QP  PQ Q P
Sbjct: 2791 PPQPPPPQAQSAPPQPTAQVQVQTSQP--PQQQSP 2823



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 35/121 (28%), Positives = 43/121 (35%), Gaps = 13/121 (10%)

Query: 232 QGPPPPNPVAAFPPQKQQQQQQ-------PQQQQQQQQAALPQMPLFENFYSMPQQPSQQ 284
           QG  PP P AA    ++Q QQQ       P Q        LPQ+P       +P      
Sbjct: 513 QGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSS 572

Query: 285 PQDFGLQPAGPLGQSHL-----AHHSMAPYPFPPNPDMN-PELRKALLQDSAPQPALPQV 338
              F  QP     Q+ L           P P PP+  +  P  + A L    P P   QV
Sbjct: 573 ALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQV 632

Query: 339 Q 339
           Q
Sbjct: 633 Q 633



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 15/108 (13%)

Query: 234  PPPPNPVAAFPPQKQQQQQQP-QQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQP 292
            P PP  VA+   ++  ++++    QQ+ QQ A+ Q          P  P  QP     QP
Sbjct: 2471 PLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQ----------PPPPQPQPPPPPQQP 2520

Query: 293  AGPLGQSHLA--HHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQV 338
              PL Q   A       P    P P   P+ +   +Q  AP  A P +
Sbjct: 2521 PPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQ--APAKAQPAI 2566



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 30/111 (27%), Positives = 41/111 (36%), Gaps = 11/111 (9%)

Query: 237 PNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYS----MPQQPSQQPQDFGLQP 292
           P      PP  Q  Q   Q+Q QQQ       P+ +N  S    +PQ P + P      P
Sbjct: 510 PTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPV-QNAASLHTPLPQLPGRLP------P 562

Query: 293 AGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFP 343
           AG    +  +    A  P         ++     Q + P PA P  Q+P P
Sbjct: 563 AGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIP 613


>gi|94721313 mesoderm induction early response 1, family member 3
           [Homo sapiens]
          Length = 549

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 50/170 (29%), Positives = 76/170 (44%), Gaps = 20/170 (11%)

Query: 715 TPVSIEPRINVGSRFQAEIP--LMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDL 772
           +P  +   I +G ++QAEIP  L           ++  L+W P   LES + K+  VE  
Sbjct: 168 SPEDLRKEIMIGLQYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVLES-KVKEYLVETS 226

Query: 773 LTAACSSIFP--GAGTN---QELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHY 827
           L      I     AGT+    E AL+ L +   +I E + +                   
Sbjct: 227 LRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQ---------- 276

Query: 828 TGSDQWKMAERKLFNKGIAIYKKDFFLVQK-LIQTKTVAQCVEFYYTYKK 876
            G   W   E + F   + ++ KDF L+QK  ++T+TVA+CV FYY +KK
Sbjct: 277 -GMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKK 325


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 90/335 (26%), Positives = 110/335 (32%), Gaps = 54/335 (16%)

Query: 117 SDSSWQQQ--PGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQ 174
           SDSS QQQ    QPP        + +  SA  G+P     +PT    P A      G P 
Sbjct: 171 SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ----LPTPGPTPSATAVPPQGSPT 226

Query: 175 LDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGP 234
             +   P  PQ        P AP+   H  + P      L P +    H          P
Sbjct: 227 ASQ--APNQPQA-------PTAPVPHTHIQQAPA-----LHPQRPPSPHP---------P 263

Query: 235 PPPNPVAAFPPQKQQ--QQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQP 292
           P P+P     P      Q   P   Q       P  P       + Q P   PQ FGL P
Sbjct: 264 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPP 322

Query: 293 AGPLGQSHLAHHSMAPYPF----------------PPNPDMNPELRKALLQDSAPQPALP 336
               GQ+ L     A YP                 PP     P    A +    P P  P
Sbjct: 323 QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA-MPHIKPPPTTP 381

Query: 337 QVQIPFPRRSRRLSK-EGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSL---GQ 392
             Q+P P+  +      G  P S        P  +   +L  HH P   PPP  L    Q
Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441

Query: 393 PHPEALGFPLELRESQLLPDGERL-APNGREREAP 426
           P P +   P  L +SQ LP       P G  + AP
Sbjct: 442 PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 476



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 87/396 (21%), Positives = 112/396 (28%), Gaps = 76/396 (19%)

Query: 21  QEPA--PKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVY 78
           Q PA  P+  P P  PP  S     +   G  G   A S +QP                 
Sbjct: 248 QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQP----------------- 290

Query: 79  GPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHS 138
                                     G+GP   G   +      Q PG P P        
Sbjct: 291 -----------------------PLHGQGPP--GPHSLQAGPLLQHPGPPQPFGL----- 320

Query: 139 LSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPL 198
                A++G    G      Y H            QL      +  Q+   E   P APL
Sbjct: 321 --PPQASQGQAPLGTSPAAAYPHTSL---------QLPASQSALQSQQPPREQPLPPAPL 369

Query: 199 NSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQ 258
              H  K PP   +P  P   A  H  +      GP P +  A  PP    +        
Sbjct: 370 AMPH-IKPPPTTPIPQLPAPQAHKHPPH----LSGPSPFSMNANLPPPPALKPLSSLSTH 424

Query: 259 QQQQAALPQMPLFENFYSMPQQPSQQP---QDFGLQPAGPLGQSHLAHHSMAPYP----F 311
               A  P + L      +P  P+Q P   Q   L P  P        H +AP P     
Sbjct: 425 HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP-PASHPPTGLHQVAPQPPFAQH 483

Query: 312 PPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEA 371
           P  P   P +       ++  PA P      P      S   I   S+      Q  +EA
Sbjct: 484 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEA 543

Query: 372 TGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRES 407
             +      P   PPP     P P  +  P    +S
Sbjct: 544 LDDA---EEPESPPPPPRSPSPEPTVVDTPSHASQS 576



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 43/168 (25%), Positives = 64/168 (38%), Gaps = 26/168 (15%)

Query: 556 QNPAEHKPSVIVTRRRSTRIP-GTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTK 614
           Q+P   +P  +  +    + P GT   A     +++L    S  + +Q PR +PL     
Sbjct: 310 QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 369

Query: 615 AGTFIAPPVYSNITPY---QSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYF 671
           A   I PP  + I      Q+H   P      P   +  LP   PPP L P+        
Sbjct: 370 AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP---PPPALKPL-------- 418

Query: 672 NAIISTSTIPA--PPPI--------TPKSAHRTLLRTNSAEVTPPVLS 709
            + +ST   P+  PPP+         P S  +    T S  + PP  S
Sbjct: 419 -SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 90/335 (26%), Positives = 110/335 (32%), Gaps = 54/335 (16%)

Query: 117  SDSSWQQQ--PGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQ 174
            SDSS QQQ    QPP        + +  SA  G+P     +PT    P A      G P 
Sbjct: 725  SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ----LPTPGPTPSATAVPPQGSPT 780

Query: 175  LDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGP 234
              +   P  PQ        P AP+   H  + P      L P +    H          P
Sbjct: 781  ASQ--APNQPQA-------PTAPVPHTHIQQAPA-----LHPQRPPSPHP---------P 817

Query: 235  PPPNPVAAFPPQKQQ--QQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQP 292
            P P+P     P      Q   P   Q       P  P       + Q P   PQ FGL P
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPP 876

Query: 293  AGPLGQSHLAHHSMAPYPF----------------PPNPDMNPELRKALLQDSAPQPALP 336
                GQ+ L     A YP                 PP     P    A +    P P  P
Sbjct: 877  QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA-MPHIKPPPTTP 935

Query: 337  QVQIPFPRRSRRLSK-EGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSL---GQ 392
              Q+P P+  +      G  P S        P  +   +L  HH P   PPP  L    Q
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 393  PHPEALGFPLELRESQLLPDGERL-APNGREREAP 426
            P P +   P  L +SQ LP       P G  + AP
Sbjct: 996  PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 47/173 (27%), Positives = 70/173 (40%), Gaps = 27/173 (15%)

Query: 718 SIEPRINVGSRFQAEIPLMRDRALAAADP--HKADLVWQPWEDLESSREKQRQVEDLLTA 775
           S +  I VG   QA++P ++       D      +LVW P  +        R    +  A
Sbjct: 281 STQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVNDCDLLMYLRAARSM--A 338

Query: 776 ACSSIFPGAGTNQEL-----------ALHCLHESRGDILETLNKLLLKKPLRPHNHPLAT 824
           A + +  G  T               AL+ LHES  D  + L +L+ KKP+         
Sbjct: 339 AFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESGYDAGKALQRLV-KKPVPKLIEKC-- 395

Query: 825 YHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQK-LIQTKTVAQCVEFYYTYKK 876
                   W   E K F KG+  Y K+FF ++K L+  K   + + FYY +KK
Sbjct: 396 --------WTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKK 440



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 87/396 (21%), Positives = 112/396 (28%), Gaps = 76/396 (19%)

Query: 21   QEPA--PKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVY 78
            Q PA  P+  P P  PP  S     +   G  G   A S +QP                 
Sbjct: 802  QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQP----------------- 844

Query: 79   GPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHS 138
                                      G+GP   G   +      Q PG P P        
Sbjct: 845  -----------------------PLHGQGPP--GPHSLQAGPLLQHPGPPQPFGL----- 874

Query: 139  LSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPL 198
                 A++G    G      Y H            QL      +  Q+   E   P APL
Sbjct: 875  --PPQASQGQAPLGTSPAAAYPHTSL---------QLPASQSALQSQQPPREQPLPPAPL 923

Query: 199  NSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQ 258
               H  K PP   +P  P   A  H  +      GP P +  A  PP    +        
Sbjct: 924  AMPH-IKPPPTTPIPQLPAPQAHKHPPH----LSGPSPFSMNANLPPPPALKPLSSLSTH 978

Query: 259  QQQQAALPQMPLFENFYSMPQQPSQQP---QDFGLQPAGPLGQSHLAHHSMAPYP----F 311
                A  P + L      +P  P+Q P   Q   L P  P        H +AP P     
Sbjct: 979  HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP-PASHPPTGLHQVAPQPPFAQH 1037

Query: 312  PPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEA 371
            P  P   P +       ++  PA P      P      S   I   S+      Q  +EA
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEA 1097

Query: 372  TGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRES 407
              +      P   PPP     P P  +  P    +S
Sbjct: 1098 LDDA---EEPESPPPPPRSPSPEPTVVDTPSHASQS 1130



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 43/168 (25%), Positives = 64/168 (38%), Gaps = 26/168 (15%)

Query: 556  QNPAEHKPSVIVTRRRSTRIP-GTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTK 614
            Q+P   +P  +  +    + P GT   A     +++L    S  + +Q PR +PL     
Sbjct: 864  QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 923

Query: 615  AGTFIAPPVYSNITPY---QSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYF 671
            A   I PP  + I      Q+H   P      P   +  LP   PPP L P+        
Sbjct: 924  AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP---PPPALKPL-------- 972

Query: 672  NAIISTSTIPA--PPPI--------TPKSAHRTLLRTNSAEVTPPVLS 709
             + +ST   P+  PPP+         P S  +    T S  + PP  S
Sbjct: 973  -SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 90/335 (26%), Positives = 110/335 (32%), Gaps = 54/335 (16%)

Query: 117  SDSSWQQQ--PGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQ 174
            SDSS QQQ    QPP        + +  SA  G+P     +PT    P A      G P 
Sbjct: 725  SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQ----LPTPGPTPSATAVPPQGSPT 780

Query: 175  LDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGP 234
              +   P  PQ        P AP+   H  + P      L P +    H          P
Sbjct: 781  ASQ--APNQPQA-------PTAPVPHTHIQQAPA-----LHPQRPPSPHP---------P 817

Query: 235  PPPNPVAAFPPQKQQ--QQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQP 292
            P P+P     P      Q   P   Q       P  P       + Q P   PQ FGL P
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPP 876

Query: 293  AGPLGQSHLAHHSMAPYPF----------------PPNPDMNPELRKALLQDSAPQPALP 336
                GQ+ L     A YP                 PP     P    A +    P P  P
Sbjct: 877  QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA-MPHIKPPPTTP 935

Query: 337  QVQIPFPRRSRRLSK-EGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSL---GQ 392
              Q+P P+  +      G  P S        P  +   +L  HH P   PPP  L    Q
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 393  PHPEALGFPLELRESQLLPDGERL-APNGREREAP 426
            P P +   P  L +SQ LP       P G  + AP
Sbjct: 996  PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 47/173 (27%), Positives = 70/173 (40%), Gaps = 27/173 (15%)

Query: 718 SIEPRINVGSRFQAEIPLMRDRALAAADP--HKADLVWQPWEDLESSREKQRQVEDLLTA 775
           S +  I VG   QA++P ++       D      +LVW P  +        R    +  A
Sbjct: 281 STQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVNDCDLLMYLRAARSM--A 338

Query: 776 ACSSIFPGAGTNQEL-----------ALHCLHESRGDILETLNKLLLKKPLRPHNHPLAT 824
           A + +  G  T               AL+ LHES  D  + L +L+ KKP+         
Sbjct: 339 AFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESGYDAGKALQRLV-KKPVPKLIEKC-- 395

Query: 825 YHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQK-LIQTKTVAQCVEFYYTYKK 876
                   W   E K F KG+  Y K+FF ++K L+  K   + + FYY +KK
Sbjct: 396 --------WTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKK 440



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 87/396 (21%), Positives = 112/396 (28%), Gaps = 76/396 (19%)

Query: 21   QEPA--PKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVY 78
            Q PA  P+  P P  PP  S     +   G  G   A S +QP                 
Sbjct: 802  QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQP----------------- 844

Query: 79   GPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHS 138
                                      G+GP   G   +      Q PG P P        
Sbjct: 845  -----------------------PLHGQGPP--GPHSLQAGPLLQHPGPPQPFGL----- 874

Query: 139  LSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPL 198
                 A++G    G      Y H            QL      +  Q+   E   P APL
Sbjct: 875  --PPQASQGQAPLGTSPAAAYPHTSL---------QLPASQSALQSQQPPREQPLPPAPL 923

Query: 199  NSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQ 258
               H  K PP   +P  P   A  H  +      GP P +  A  PP    +        
Sbjct: 924  AMPH-IKPPPTTPIPQLPAPQAHKHPPH----LSGPSPFSMNANLPPPPALKPLSSLSTH 978

Query: 259  QQQQAALPQMPLFENFYSMPQQPSQQP---QDFGLQPAGPLGQSHLAHHSMAPYP----F 311
                A  P + L      +P  P+Q P   Q   L P  P        H +AP P     
Sbjct: 979  HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP-PASHPPTGLHQVAPQPPFAQH 1037

Query: 312  PPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEA 371
            P  P   P +       ++  PA P      P      S   I   S+      Q  +EA
Sbjct: 1038 PFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEA 1097

Query: 372  TGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRES 407
              +      P   PPP     P P  +  P    +S
Sbjct: 1098 LDDA---EEPESPPPPPRSPSPEPTVVDTPSHASQS 1130



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 43/168 (25%), Positives = 64/168 (38%), Gaps = 26/168 (15%)

Query: 556  QNPAEHKPSVIVTRRRSTRIP-GTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTK 614
            Q+P   +P  +  +    + P GT   A     +++L    S  + +Q PR +PL     
Sbjct: 864  QHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL 923

Query: 615  AGTFIAPPVYSNITPY---QSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYF 671
            A   I PP  + I      Q+H   P      P   +  LP   PPP L P+        
Sbjct: 924  AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLP---PPPALKPL-------- 972

Query: 672  NAIISTSTIPA--PPPI--------TPKSAHRTLLRTNSAEVTPPVLS 709
             + +ST   P+  PPP+         P S  +    T S  + PP  S
Sbjct: 973  -SSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 95/383 (24%), Positives = 132/383 (34%), Gaps = 80/383 (20%)

Query: 21  QEPAPKEQPPPLQPP--QQSIR----------VKEEQYLGHEGPGGA------VSTSQPV 62
           Q P   + PPP  PP  QQ IR          +   Q+  H  P         + T + +
Sbjct: 312 QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMM 371

Query: 63  ELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGG--------G 114
             PPP +     ++   P      +   QV  +  P S   P  GP+R  G         
Sbjct: 372 MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVP-SQPRPAVGPQRFPGPPEFPQHTP 430

Query: 115 GVSDSSWQQQP--------GQPPPHSTWNCHSLSLYSATK---------GSPHPGVGVPT 157
           G   +S+ Q P          PPP    +   L +    +          SP P    PT
Sbjct: 431 GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPT 490

Query: 158 YYN--HP----EALKREKAGGPQLDRYVRPMMPQKVQLEVG-RPQAPLNSFHAAKK---- 206
             N  HP      L   + G     +  +P+ P++  +    +P  P+   H ++     
Sbjct: 491 LLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSAT 550

Query: 207 -----PPNQSL---PLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQ 258
                PP Q     P QPF        + Q   QGP  P       PQ QQ QQQP  Q 
Sbjct: 551 TRPFIPPRQPFLPGPGQPFL-----PTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQH 605

Query: 259 QQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMN 318
           Q       Q P        PQ P Q P         P  Q H  HH ++  P P  P   
Sbjct: 606 QPPHQPPHQPP--PQHQPPPQHPPQHP---------PQHQHHHHHHHLSVPPPPLMPMSQ 654

Query: 319 PELRKALLQDSAPQPALPQVQIP 341
           P+ R   +Q + PQ +  ++Q P
Sbjct: 655 PQFRPH-VQTAQPQASSSRMQCP 676



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 80/333 (24%), Positives = 107/333 (32%), Gaps = 60/333 (18%)

Query: 20  GQEPAPKEQPP--PLQ------PPQQSIRVKEEQYLGHEGPGGAVS---TSQPVELPPPS 68
           G  P    QPP  PLQ      PP Q    ++  +LG  G     S     Q    PPP 
Sbjct: 431 GPVPNSFSQPPRLPLQDQWRAPPPPQD---RDPFFLGVSGEPRFPSHLFLEQRSPPPPPP 487

Query: 69  SLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQP 128
              LLNS    P ++              P     PG    + G   V       +P   
Sbjct: 488 PPTLLNSSHPVPTQS--------------PLPFTQPGPAFNQQGQQPVFPRERPVRPALQ 533

Query: 129 PPHSTWNCHSLSLYSATKGS---PH----PGVGVPTYYNHPEALKREKAGGPQLDRYVRP 181
           PP      H     SAT      P     PG G P    H +         P L   + P
Sbjct: 534 PPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQ---------PNLQGPLHP 584

Query: 182 MMPQKVQLEVGRPQA-PLNSFHAAKKPPNQS------LPLQPFQLAFGHQVNRQVFRQGP 234
            +P   Q +  +PQ  P        +PP+Q        P  P Q    HQ +        
Sbjct: 585 PLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSV 644

Query: 235 PPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQM------PLFENFYSMPQQPSQ--QPQ 286
           PPP  +    PQ +   Q  Q Q    +   PQ          +N    P Q  Q   P+
Sbjct: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704

Query: 287 DFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNP 319
           +  L+   P+  SH+   S +     P+  + P
Sbjct: 705 NSNLREL-PIAPSHVIEMSSSRCSATPSAQVKP 736



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 53/210 (25%), Positives = 68/210 (32%), Gaps = 56/210 (26%)

Query: 229 VFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDF 288
           V  Q PPPP P           QQQP +   Q Q   P +P+       P  PS  PQ  
Sbjct: 315 VVPQAPPPPPP---------PPQQQPIRSLFQPQPLQPLLPV-----QHPHHPS-PPQGM 359

Query: 289 GLQPAGPLGQSHLAHHSMAPYPF----PPNPDMNPELRKALLQ---------DSAPQPAL 335
            + P     Q       M P P     P N  +NP  +  ++           S P+PA+
Sbjct: 360 HMPP-----QLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAV 414

Query: 336 PQVQIP----FPRRS-------------RRLSKEGILPPSALDG----AGTQPGQEATGN 374
              + P    FP+ +               L  +   PP   D      G         +
Sbjct: 415 GPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSH 474

Query: 375 LFLHHW--PLQQPPPGSLGQPHPEALGFPL 402
           LFL     P   PPP  L   HP     PL
Sbjct: 475 LFLEQRSPPPPPPPPTLLNSSHPVPTQSPL 504


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 3/144 (2%)

Query: 831 DQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGD 890
           + W   E++ F +    + K+F L+   ++ KTVA+CV +YY  KK          ++  
Sbjct: 430 NMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRR 489

Query: 891 VDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQ 950
              S ++  Q++ +   +  Q  PR     ++   +E+ E ++E ++P  E ++E   ++
Sbjct: 490 RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEK-EAEKEEEKPEVENDKE-DLLK 547

Query: 951 EKEEQEEGRER-SRRAAAVKATQT 973
           EK +   G +   + A A K  +T
Sbjct: 548 EKTDDTSGEDNDEKEAVASKGRKT 571



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 39/185 (21%), Positives = 72/185 (38%), Gaps = 36/185 (19%)

Query: 822  LATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIG 881
            LA+     S +W   E +   KG+  + +++  + +++ +KTV+QC  FY+ YKK+  + 
Sbjct: 604  LASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL- 662

Query: 882  RNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKE 941
                         DE   Q +++++                   +ER   +++ K P   
Sbjct: 663  -------------DEILQQHKLKME-------------------KERNARRKKKKAPAAA 690

Query: 942  GEEEV-PEIQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQ 1000
             EE   P + E EE E           V+  +    N  +SD   + S  + A    G  
Sbjct: 691  SEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNN--SSDTESIPSPHTEAAKDTGQN 748

Query: 1001 ASEKP 1005
              + P
Sbjct: 749  GPKPP 753



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 70/280 (25%), Positives = 103/280 (36%), Gaps = 46/280 (16%)

Query: 194  PQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQ 253
            PQ PL+     K+   ++  + P Q+   H+  R+     P  P P A  PPQ  Q +  
Sbjct: 940  PQKPLD----LKQLKQRAAAIPPIQVTKVHEPPRE--DAAPTKPAPPAPPPPQNLQPESD 993

Query: 254  PQQQQ------QQQQAALP-----QMPLFENFYSMPQQ--PSQQP-QDFGLQ-PAGPLGQ 298
              QQ       + +  A P     + P+F   ++   Q  P   P    GL  P  P   
Sbjct: 994  APQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREV 1053

Query: 299  SHLAHHSMAPYPFPPNPDMNPELRKALLQDSAP-QPALPQVQIPFPRRSRRLSKEGILPP 357
               + H+  P  F   P  +P L   L   + P  P  P +  P P  S          P
Sbjct: 1054 IKASPHAPDPSAFSYAPPGHP-LPLGLHDTARPVLPRPPTISNPPPLIS------SAKHP 1106

Query: 358  SALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLP----DG 413
            S L+    Q G  + G     H P  +     +G   P  +G PL +   +L P      
Sbjct: 1107 SVLE---RQIGAISQGMSVQLHVPYSEHAKAPVG---PVTMGLPLPMDPKKLAPFSGVKQ 1160

Query: 414  ERLAPNGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQS 453
            E+L+P G+     ++G       V T     VLRG  + S
Sbjct: 1161 EQLSPRGQAGPPESLG-------VPTAQEASVLRGTALGS 1193



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 15/21 (71%), Positives = 18/21 (85%)

Query: 247 KQQQQQQPQQQQQQQQAALPQ 267
           +QQQQQQ QQQQQQQQ  +P+
Sbjct: 494 QQQQQQQQQQQQQQQQQPMPR 514



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 15/17 (88%), Positives = 16/17 (94%)

Query: 246 QKQQQQQQPQQQQQQQQ 262
           Q+QQQQQQ QQQQQQQQ
Sbjct: 494 QQQQQQQQQQQQQQQQQ 510



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 9/133 (6%)

Query: 916  VPLPRRESPSEERL-EPKREVKEPRKEGEEEVPEIQEKEEQ-------EEGRERSRRAAA 967
            +P P   +P+ E    P      P       V   +EKEE+       EEG E+   AA 
Sbjct: 773  IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE 832

Query: 968  VKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSEKKKKTET 1027
              A  T +A E         + E  A G    +A+E   EG  K+ +    S +    ++
Sbjct: 833  ELAVDTGKAEEPVKSECTEEAEEGPAKGK-DAEAAEATAEGALKAEKKEGGSGRATTAKS 891

Query: 1028 FSKTQNQENTFPC 1040
                Q+ +++  C
Sbjct: 892  SGAPQDSDSSATC 904



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 247 KQQQQQQPQQQQQQQQAALP 266
           K QQQQQ QQQQQQQQ   P
Sbjct: 492 KSQQQQQQQQQQQQQQQQQP 511



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 14/17 (82%), Positives = 15/17 (88%)

Query: 246 QKQQQQQQPQQQQQQQQ 262
           + QQQQQQ QQQQQQQQ
Sbjct: 492 KSQQQQQQQQQQQQQQQ 508


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 3/144 (2%)

Query: 831 DQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGD 890
           + W   E++ F +    + K+F L+   ++ KTVA+CV +YY  KK          ++  
Sbjct: 430 NMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRR 489

Query: 891 VDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQ 950
              S ++  Q++ +   +  Q  PR     ++   +E+ E ++E ++P  E ++E   ++
Sbjct: 490 RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEK-EAEKEEEKPEVENDKE-DLLK 547

Query: 951 EKEEQEEGRER-SRRAAAVKATQT 973
           EK +   G +   + A A K  +T
Sbjct: 548 EKTDDTSGEDNDEKEAVASKGRKT 571



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 34/157 (21%)

Query: 822 LATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIG 881
           LA+     S +W   E +   KG+  + +++  + +++ +KTV+QC  FY+ YKK+  + 
Sbjct: 604 LASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL- 662

Query: 882 RNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKE 941
                        DE   Q +++++                   +ER   +++ K P   
Sbjct: 663 -------------DEILQQHKLKME-------------------KERNARRKKKKAPAAA 690

Query: 942 GEEEV-PEIQEKEEQEEGRERSRRAAAVKATQTLQAN 977
            EE   P + E EE E           V+  + L A+
Sbjct: 691 SEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHAS 727



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 15/21 (71%), Positives = 18/21 (85%)

Query: 247 KQQQQQQPQQQQQQQQAALPQ 267
           +QQQQQQ QQQQQQQQ  +P+
Sbjct: 494 QQQQQQQQQQQQQQQQQPMPR 514



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 15/17 (88%), Positives = 16/17 (94%)

Query: 246 QKQQQQQQPQQQQQQQQ 262
           Q+QQQQQQ QQQQQQQQ
Sbjct: 494 QQQQQQQQQQQQQQQQQ 510



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 9/133 (6%)

Query: 916  VPLPRRESPSEERL-EPKREVKEPRKEGEEEVPEIQEKEEQ-------EEGRERSRRAAA 967
            +P P   +P+ E    P      P       V   +EKEE+       EEG E+   AA 
Sbjct: 790  IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE 849

Query: 968  VKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSEKKKKTET 1027
              A  T +A E         + E  A G    +A+E   EG  K+ +    S +    ++
Sbjct: 850  ELAVDTGKAEEPVKSECTEEAEEGPAKGK-DAEAAEATAEGALKAEKKEGGSGRATTAKS 908

Query: 1028 FSKTQNQENTFPC 1040
                Q+ +++  C
Sbjct: 909  SGAPQDSDSSATC 921



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 247 KQQQQQQPQQQQQQQQAALP 266
           K QQQQQ QQQQQQQQ   P
Sbjct: 492 KSQQQQQQQQQQQQQQQQQP 511



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 14/17 (82%), Positives = 15/17 (88%)

Query: 246 QKQQQQQQPQQQQQQQQ 262
           + QQQQQQ QQQQQQQQ
Sbjct: 492 KSQQQQQQQQQQQQQQQ 508


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 140/611 (22%), Positives = 205/611 (33%), Gaps = 100/611 (16%)

Query: 104 PGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPE 163
           PG GP  G G G   +S +  P +P          L    A   +P         +  P 
Sbjct: 61  PGPGPGPGPGPGPGSTSRRLDPKEP----------LGNQRAASPTPKQASATTPGHESPR 110

Query: 164 ALKREKAGGPQLDRYVRPMMPQKVQLEVGR-----------PQAPLNSFHAAKKPPNQSL 212
             + +   G + D   R +         GR           P +P +    A  P +   
Sbjct: 111 ETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLC 170

Query: 213 PL--------QPFQLAFG--HQVNRQVFRQGPPPPNP----VAAFPPQKQQQQQ------ 252
           P+         P Q  F    Q + +V  Q    PNP    V  +     Q Q+      
Sbjct: 171 PICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDM 230

Query: 253 --QPQQQQQQQQAALPQMPLFENFYSMPQQPSQQP-QDFGLQPAGPLGQSHLAHHSMA-P 308
              P+ + QQQ       P     +S  +QP  +P Q+    P GP   S  A  + A  
Sbjct: 231 TTAPRSKSQQQL----HSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATS 286

Query: 309 YPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPG 368
            P P      PE+ +  +    PQP  P    P P      +K     P+ L GA  Q  
Sbjct: 287 VPGPAQAAAPPEVGR--VSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGL-GATEQTQ 343

Query: 369 QEATGNLFLHHWPL---------QQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPN 419
           +  TG LF     L          QP   + GQP P      +   ++      + L   
Sbjct: 344 EGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSG 403

Query: 420 GREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAV----E 475
                AP   +E G R       G + + G   S +  R   Q A+      K +     
Sbjct: 404 PGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERA 463

Query: 476 LASLQNAKDGSGSEEKRKSVLASTTK------CG-------VEFSE---PSLATKRARED 519
           +  L  A+   GS+        +T +      CG       VE +E    +  TKR  E 
Sbjct: 464 ICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEG 523

Query: 520 SGMVPLII--------PVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRR 571
           S   P  +        PV  P R    +   Q G     G G    P   K S + T  +
Sbjct: 524 SLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKG---PQGLGQPSGPLPAKASPLST--K 578

Query: 572 STRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQ 631
           ++ +P + A  QA+ +      EPS  K     + +   +PTKA     PP  +  TP  
Sbjct: 579 ASPLP-SKASPQAKPLRA---SEPS--KTPSSVQEKKTRVPTKAEPMPKPPPETTPTPAT 632

Query: 632 SHLRSPVRLAD 642
             ++S VR A+
Sbjct: 633 PKVKSGVRRAE 643



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 62/236 (26%), Positives = 83/236 (35%), Gaps = 29/236 (12%)

Query: 79   GPERTSAAMLSQQVASVKWPNSVMAPGRGPE-----RGGGGGVSDSSWQQQPGQ--PPPH 131
            GP R S     +      WP+    PGR         G  G  S     ++PG+    PH
Sbjct: 3611 GPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPH 3670

Query: 132  ST-WNCHSLSLYSATKGSPH-PGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQL 189
            +     H    +S    +P  P  G P Y +  E  +  +A       Y      +K   
Sbjct: 3671 ARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSA----YHHASDSKKGSR 3726

Query: 190  EVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQ 249
            +     A L S    K  P     LQ  Q A G Q ++    +    P+  A+  PQ QQ
Sbjct: 3727 QAHSGPAALQS----KAEPQAQPQLQGRQAAPGPQQSQSPSSR--QIPSGAASRQPQTQQ 3780

Query: 250  QQ-----QQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQD-----FGLQPAGP 295
            QQ     Q PQQ   Q +      P          QP+ +PQ       G QPAGP
Sbjct: 3781 QQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGP 3836



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)

Query: 26   KEQPPPLQPPQQSI-RVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGPERTS 84
            ++Q   LQPPQQ++ + + +Q       G A + SQP   P P           GP R  
Sbjct: 3781 QQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAE 3840

Query: 85   AAMLSQQVASV----KWPNSVMAPGRGP---ERGGGGGVSDSSWQQQPG 126
                S+  A      + P +  APG GP   + G   G +  +   QPG
Sbjct: 3841 QTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPG 3889



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 48/186 (25%), Positives = 65/186 (34%), Gaps = 26/186 (13%)

Query: 47   LGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGPERTSAAM---LSQQVASVKWPNSVMA 103
            L   GP     T+    LP  +++   + ++Y    T  A    ++ Q ASV  P     
Sbjct: 2164 LAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGG 2223

Query: 104  PGRGPERGGGGGVSDSSWQQQPGQPP-----PHSTWNCHSLSLYSATKGSPHPGVGVPTY 158
              R    GG   V  +S  + P   P     P   +   + S +      P P  G P Y
Sbjct: 2224 MYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVP-PAEG-PVY 2281

Query: 159  YNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQ-----------APLNSFHAAKKP 207
               P A K   AGGP      RP MP     E   P            AP  +  A +KP
Sbjct: 2282 LGKPAAAKAPGAGGPS-----RPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKP 2336

Query: 208  PNQSLP 213
            P  + P
Sbjct: 2337 PADAAP 2342


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 95/432 (21%), Positives = 141/432 (32%), Gaps = 105/432 (24%)

Query: 18  FGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVV 77
           +GG  P  ++Q PP  P Q           GH  PG    +  P   P           +
Sbjct: 395 YGGTNPYSQQQGPPSGPQQ-----------GHGYPGQPYGSQTPQRYP---------MTM 434

Query: 78  YGPERTSAAMLS--QQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWN 135
            G  +++   LS  QQ+           P  G +   G G        Q GQ P ++   
Sbjct: 435 QGRAQSAMGGLSYTQQI-----------PPYGQQGPSGYG--------QQGQTPYYN--- 472

Query: 136 CHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQ 195
                     + SPHP    P Y   P          P    + +P   Q+ Q +  + Q
Sbjct: 473 ----------QQSPHPQQQQPPYSQQP----------PSQTPHAQPSYQQQPQSQPPQLQ 512

Query: 196 APLNSF-HAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQP 254
           +    +     +PP+Q  P  P+      Q   Q   Q  PP +   A  P +QQQ QQP
Sbjct: 513 SSQPPYSQQPSQPPHQQSPA-PYP---SQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568

Query: 255 QQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQ---PAGPLGQSHLAHHSMAPYPF 311
                 QQAA PQ          PQ    Q   +  Q   P   L Q      + +    
Sbjct: 569 APSTLSQQAAYPQ----------PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSM 618

Query: 312 PPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPS-ALDGAGTQPGQE 370
             +     ++  +L    +  P L       P     +  EG L P  +  G  +  G++
Sbjct: 619 TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP-----MGTEGALSPGVSTSGISSSQGEQ 673

Query: 371 ATGNLFLHHWPLQQP--------PPGSLGQPHPEALGFPLELRESQLLPDGERLAPNGRE 422
           +         P Q P         PG  G P P  +G P  + +S+  P      P  + 
Sbjct: 674 SN--------PAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724

Query: 423 REAPAMGSEEGM 434
              P  G  + +
Sbjct: 725 PPRPPSGQSDSI 736



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 41/379 (10%)

Query: 25   PKEQPPP------LQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVY 78
            PK QPP       +Q PQ           G +      +++   ++PP   ++  NSV  
Sbjct: 1128 PKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGI 1187

Query: 79   GPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHS 138
                   +  + Q  +   PN    PG  P       +   S++  P + P  S      
Sbjct: 1188 QDAFNDGSDSTFQKRNSMTPN----PGYQPSMNTSDMMGRMSYE--PNKDPYGSMRKAPG 1241

Query: 139  LSLYSATKGSPHPGVGVPTYYNHPEAL--------KREKAGGPQLDRYVRPMMPQKVQLE 190
               + ++   P+ G+G P        L        +    GGP       P +  +  + 
Sbjct: 1242 SDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMS 1301

Query: 191  VGRPQAPL-------NSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAF 243
             G PQ  L         +  ++ PP Q    Q    ++G+Q + Q    G P P+     
Sbjct: 1302 TGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTM 1361

Query: 244  PPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQ-QPQDFGLQPAGPLGQSHLA 302
              Q+QQ  ++P        A   +       YS+P    Q QPQ   L PA P   S   
Sbjct: 1362 YQQQQQNYKRPMDGTYGPPAKRHE----GEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQ 1417

Query: 303  HHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLS------KEGILP 356
                +P     N   N     A           PQ Q PF     R+S       +  +P
Sbjct: 1418 AAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMP 1477

Query: 357  PSALDG---AGTQPGQEAT 372
            P  + G   A  +  Q+ T
Sbjct: 1478 PQMMGGPIQASAEVAQQGT 1496



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 73/337 (21%), Positives = 116/337 (34%), Gaps = 48/337 (14%)

Query: 21  QEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPP------------S 68
           Q  +P +Q  P QP   ++  ++  Y   +      +       PPP            S
Sbjct: 555 QAQSPYQQQQPQQPAPSTLS-QQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQAS 613

Query: 69  SLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQP 128
           S   + S   G E  + ++ S+  +      S+     G E     GVS S      G+ 
Sbjct: 614 SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ 673

Query: 129 --PPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGP-----------QL 175
             P  S ++ H+       +G     VG P       +     A  P           Q 
Sbjct: 674 SNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQS 733

Query: 176 DRYVRPMMPQK-VQLEVGRPQA-PLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQG 233
           D  + P M Q  +  + G  Q  P    +++ +P +   P QP     G Q++  +   G
Sbjct: 734 DSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPS----GGQIHTGM---G 786

Query: 234 PPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQ-- 291
               N + ++ PQ  Q   Q    +Q    ALP      N+ S        P   G Q  
Sbjct: 787 SYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNA----NYPSAGMAGGINPMGAGGQMH 842

Query: 292 ------PAGPLGQSHLAHHSMAPYPFPPN-PDMNPEL 321
                 P G L    ++H SM   P+ PN  +M P++
Sbjct: 843 GQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQV 879


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 95/432 (21%), Positives = 141/432 (32%), Gaps = 105/432 (24%)

Query: 18  FGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVV 77
           +GG  P  ++Q PP  P Q           GH  PG    +  P   P           +
Sbjct: 395 YGGTNPYSQQQGPPSGPQQ-----------GHGYPGQPYGSQTPQRYP---------MTM 434

Query: 78  YGPERTSAAMLS--QQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWN 135
            G  +++   LS  QQ+           P  G +   G G        Q GQ P ++   
Sbjct: 435 QGRAQSAMGGLSYTQQI-----------PPYGQQGPSGYG--------QQGQTPYYN--- 472

Query: 136 CHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQ 195
                     + SPHP    P Y   P          P    + +P   Q+ Q +  + Q
Sbjct: 473 ----------QQSPHPQQQQPPYSQQP----------PSQTPHAQPSYQQQPQSQPPQLQ 512

Query: 196 APLNSF-HAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQP 254
           +    +     +PP+Q  P  P+      Q   Q   Q  PP +   A  P +QQQ QQP
Sbjct: 513 SSQPPYSQQPSQPPHQQSPA-PYP---SQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568

Query: 255 QQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQ---PAGPLGQSHLAHHSMAPYPF 311
                 QQAA PQ          PQ    Q   +  Q   P   L Q      + +    
Sbjct: 569 APSTLSQQAAYPQ----------PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSM 618

Query: 312 PPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPS-ALDGAGTQPGQE 370
             +     ++  +L    +  P L       P     +  EG L P  +  G  +  G++
Sbjct: 619 TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP-----MGTEGALSPGVSTSGISSSQGEQ 673

Query: 371 ATGNLFLHHWPLQQP--------PPGSLGQPHPEALGFPLELRESQLLPDGERLAPNGRE 422
           +         P Q P         PG  G P P  +G P  + +S+  P      P  + 
Sbjct: 674 SN--------PAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724

Query: 423 REAPAMGSEEGM 434
              P  G  + +
Sbjct: 725 PPRPPSGQSDSI 736



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 91/363 (25%), Positives = 129/363 (35%), Gaps = 98/363 (26%)

Query: 59   SQPVELPPPSSLALLNSVVYGPERTSAAMLS----QQVASVKWPNSVMAPGRGPERGGGG 114
            SQP   PP  + +        P+ TS++M      +       P+S + P  G  R    
Sbjct: 1126 SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV 1185

Query: 115  GV-------SDSSWQQQ------PGQPPPHSTWNCHSLSLYSATK---GSPHPGVGVPTY 158
            G+       SDS++Q++      PG  P  +T +      Y   K   GS     G    
Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG---- 1241

Query: 159  YNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQ 218
             + P     +   G   D Y R   P    + +G  Q      H     P   +  +P  
Sbjct: 1242 -SDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQ------HYPYGGPYDRVRTEP-- 1292

Query: 219  LAFGHQVNRQVFRQGPPPPNPVAA-----------FPPQKQQQQQQ-------------- 253
               G + N      G P PN + +           +PPQ+QQQQQQ              
Sbjct: 1293 -GIGPEGNMST---GAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT 1348

Query: 254  ------PQQQ----QQQQQAALPQMPL---FENFYSMPQQPSQQP---QDFGLQPAG-PL 296
                  P QQ    QQQQQ + P  PL    EN  S    PS+ P       +Q AG P+
Sbjct: 1349 PSGSPFPSQQTTMYQQQQQVSSP-APLPRPMENRTS----PSKSPFLHSGMKMQKAGPPV 1403

Query: 297  GQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILP 356
              SH+A       P P  P M       + +D    P   +   P  ++ RRL+ + I  
Sbjct: 1404 PASHIA-------PAPVQPPM-------IRRDITFPPGSVEATQPVLKQRRRLTMKDIGT 1449

Query: 357  PSA 359
            P A
Sbjct: 1450 PEA 1452



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 73/337 (21%), Positives = 116/337 (34%), Gaps = 48/337 (14%)

Query: 21  QEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPP------------S 68
           Q  +P +Q  P QP   ++  ++  Y   +      +       PPP            S
Sbjct: 555 QAQSPYQQQQPQQPAPSTLS-QQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQAS 613

Query: 69  SLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQP 128
           S   + S   G E  + ++ S+  +      S+     G E     GVS S      G+ 
Sbjct: 614 SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQ 673

Query: 129 --PPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGP-----------QL 175
             P  S ++ H+       +G     VG P       +     A  P           Q 
Sbjct: 674 SNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQS 733

Query: 176 DRYVRPMMPQK-VQLEVGRPQA-PLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQG 233
           D  + P M Q  +  + G  Q  P    +++ +P +   P QP     G Q++  +   G
Sbjct: 734 DSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPS----GGQIHTGM---G 786

Query: 234 PPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQ-- 291
               N + ++ PQ  Q   Q    +Q    ALP      N+ S        P   G Q  
Sbjct: 787 SYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNA----NYPSAGMAGGINPMGAGGQMH 842

Query: 292 ------PAGPLGQSHLAHHSMAPYPFPPN-PDMNPEL 321
                 P G L    ++H SM   P+ PN  +M P++
Sbjct: 843 GQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQV 879


>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
          Length = 436

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%)

Query: 723 INVGSRFQAEIPLMRDRALAAADPHKAD-LVWQPWEDLESSREKQRQVEDLLTAACSSIF 781
           + VG+ +QA IP     A    D      LVW P+  +  +R     +++ +  A     
Sbjct: 59  MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAR-----LDEYIAIAKEK-- 111

Query: 782 PGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLF 841
              G N E AL  L   + +I ++L  L       P+  P         D+W + ++ LF
Sbjct: 112 --HGYNVEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKVLF 155

Query: 842 NKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKK 876
            +  + + K F  +Q+++  KT+A  V++YY++KK
Sbjct: 156 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 74/297 (24%), Positives = 94/297 (31%), Gaps = 45/297 (15%)

Query: 104 PGR--GPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNH 161
           PG+  GP   GG          +P  PPP    +    S     +G P  G   P     
Sbjct: 54  PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 113

Query: 162 PEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAF 221
           P      K  GP      RP  P       G+PQ P      ++ P +     Q      
Sbjct: 114 PPG----KPQGPPPQGGNRPQGPPPP----GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165

Query: 222 GHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQP 281
           G+Q       QGPPPP      PP +  ++ Q      + Q   PQ     +  S P +P
Sbjct: 166 GNQP------QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219

Query: 282 SQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIP 341
              P   G QP GP              P PP     P  +        P P  PQ    
Sbjct: 220 QGPPPQGGNQPQGP--------------PPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-- 263

Query: 342 FPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQP-HPEA 397
            P +    S+    PP    G   Q G    G           PPP + G P  P+A
Sbjct: 264 -PAQGGSKSQSARSPPGKPQGPPQQEGNNPQG-----------PPPPAGGNPQQPQA 308



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 52/209 (24%), Positives = 68/209 (32%), Gaps = 35/209 (16%)

Query: 232 QGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQ 291
           QGPPPP      PP +   + Q      + Q   PQ     +  S P +P   P   G Q
Sbjct: 48  QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107

Query: 292 PAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSK 351
           P GP              P PP     P  +        P P  PQ   P   +SR    
Sbjct: 108 PQGP--------------PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS 153

Query: 352 EGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEA----LGFPLELRES 407
               PP    G   Q G +  G           PPPG    P P+      G P   +  
Sbjct: 154 ----PPGKPQGPPPQGGNQPQG---------PPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200

Query: 408 QLLPDGER----LAPNGREREAPAMGSEE 432
              P G++     +P G+ +  P  G  +
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 83/329 (25%), Positives = 110/329 (33%), Gaps = 62/329 (18%)

Query: 108  PERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKR 167
            PE  G GG   S    +P   PP    +  +L +     G+  P  G P           
Sbjct: 2258 PESPGVGGGKAS----EPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSG 2313

Query: 168  EKAGGPQL---DRYVRPMMPQKVQLEVG------RPQAPLNSFHAAKKPPNQSLPLQPFQ 218
               GG +L   D +  P+ P+  Q+E        RPQ P  +   A  PP+     +P  
Sbjct: 2314 THLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGS 2373

Query: 219  LAFGHQVNRQVFRQGPPPPNPVAAFPPQK------QQQQQQPQQQQQQQQAALPQMPLFE 272
                +       R  PPPP    A PP+        +    PQ Q   Q    P+    E
Sbjct: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433

Query: 273  NFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQ 332
             F   P  P  Q  D                    PY  PP+   + +    L +   PQ
Sbjct: 2434 AFCPSPVTPRFQSPD--------------------PYSRPPSRPQSRDPFAPLHKPPRPQ 2473

Query: 333  PALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHH--WPLQQPP---- 386
            P  P+V            K G L  ++L GAG  P     G     H   P  QPP    
Sbjct: 2474 P--PEVAF----------KAGSLAHTSL-GAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520

Query: 387  -PGS---LGQPHPEALGFPLELRESQLLP 411
             PG+   +G P P    FP  + E  L P
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 101/469 (21%), Positives = 175/469 (37%), Gaps = 74/469 (15%)

Query: 246  QKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQP-----QDFGLQPAGPLGQSH 300
            Q  Q+ QQ QQQQQQQQ  L Q+       ++ QQ  Q P     Q  G +P G +  S 
Sbjct: 3729 QLAQKLQQQQQQQQQQQHLLGQV-------AIQQQQQQGPGVQTNQALGPKPQGLMPPS- 3780

Query: 301  LAHHSMAPYPFPPNPDMNPE-----LRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGIL 355
             +H  +      P P   P+      + A+LQ   P    PQ     P R   +++  +L
Sbjct: 3781 -SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQ----GPHRQVLMTQSRVL 3835

Query: 356  --PPSALDGAG--------------TQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEA-- 397
              P  A  G G               Q  Q+      L H  LQQ      GQP   A  
Sbjct: 3836 SSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH--LQQSLMSHSGQPKLSAQP 3893

Query: 398  LGFPLELRESQLLPDGERLAPNGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRR 457
            +G   +L++ Q L   ++L    +++        +  + +      Q  +   +Q  +++
Sbjct: 3894 MGSLQQLQQQQQLQQQQQLQQQQQQQ-------LQQQQQLQQQQLQQQQQQQQLQQQQQQ 3946

Query: 458  RRASQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLA----STTKCGVEFSEPSLAT 513
            +   Q+  L    Q+  +    Q  +   G   + +++L+       +  +    P+   
Sbjct: 3947 QLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPL 4006

Query: 514  KRAREDSGMVPLIIPVSVPVRTVDPTEAAQA--------GGLDEDGKGPEQ---NPAEHK 562
            +       + P ++       TVDP  +++A        GG    G  PE     P E K
Sbjct: 4007 QHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK 4066

Query: 563  PSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTF--IA 620
            PS+       +++     Q Q +  +++L  +P +R P Q+ +   L+     G+   + 
Sbjct: 4067 PSL----SGDSQLLLVQPQPQPQPSSLQL--QPPLRLPGQQQQQVSLLHTAGGGSHGQLG 4120

Query: 621  PPVYSNITPYQSHLRSP-VRLADHPSERSFELPPYTPPPILSPVREGSG 668
                S  +     L  P V L D P   +  L     P +  P++  +G
Sbjct: 4121 SGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTG 4169



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 147/681 (21%), Positives = 232/681 (34%), Gaps = 121/681 (17%)

Query: 122  QQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRP 181
            ++ P  PPP S       S +S  + SP          + PE    E    P L+  + P
Sbjct: 499  EESPLSPPPES-------SPFSPLEESP---------LSPPE----ESPPSPALETPLSP 538

Query: 182  MMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVA 241
              P+   L     ++PL+       PP + LP  P           +  R  PPP     
Sbjct: 539  P-PEASPLSPPFEESPLS-------PPPEELPTSP---------PPEASRLSPPPEESPM 581

Query: 242  AFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHL 301
            + PP++      P+  +           LF  F   P  P  +       P  P  ++  
Sbjct: 582  SPPPEESPMSPPPEASR-----------LFPPFEESPLSPPPEES-----PLSPPPEASR 625

Query: 302  AHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALD 361
                    P  P P+ +P      +   +P P + ++  P         +E  L P   +
Sbjct: 626  LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP--------PEESPLSPPPEE 677

Query: 362  GAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLP---------- 411
               + P + +  +      P   PP  S   P PE     L L ES LLP          
Sbjct: 678  SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737

Query: 412  -DGERLAPNGREREAPAMGSEEGMR-AVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTL 469
             +G  L+P   E        E  +                 + +       S +A    L
Sbjct: 738  SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797

Query: 470  AQKAVELASLQNAKDGSGS---EEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVP-L 525
            + +  EL      ++   S   EE   S     +    +  EP L+ +   E+S + P L
Sbjct: 798  SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR--PEESHLSPEL 855

Query: 526  IIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAE 585
              P   P     P E  Q    +E    P   P E   S ++     +           E
Sbjct: 856  EKPPLSPRPEKPPEEPGQCPAPEELPLFPP--PGEPSLSPLLGEPALSEPGEPPLSPLPE 913

Query: 586  DMNVKLEGEPSVRKPKQRPRPEPLIIP-TKAGTFIAPPVYSNI------------TPYQS 632
            ++ +   GEPS+  P+  P P+PL  P +   T  APP  S +            +  +S
Sbjct: 914  ELPLSPSGEPSL-SPQLMP-PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPES 971

Query: 633  HLRSPV--RLADHPSERSFELPPYTPPPIL-----SPVREGSGLYFNAIISTSTIPAPPP 685
             L +P+       P E +   P   PP IL     SPV   S +           P PP 
Sbjct: 972  PLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME--------PLPPQ 1023

Query: 686  ITPKSAHRTLLRTNS--AEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALA- 742
             +P   H +L+  NS  ++ +PP L  +   +P+S   ++ VG   +AE+  M    ++ 
Sbjct: 1024 CSPLLQH-SLVPQNSPPSQCSPPALP-LSVPSPLSPIGKV-VGVSDEAELHEMETEKVSE 1080

Query: 743  ----AADPHKADLVWQPWEDL 759
                A +P     +  P  DL
Sbjct: 1081 PECPALEPSATSPLPSPMGDL 1101



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 126/612 (20%), Positives = 198/612 (32%), Gaps = 56/612 (9%)

Query: 128 PPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKRE-----KAG---GPQLDRYV 179
           P P  T      +LY A +G P  G         P  L+ E     KAG    PQL+  +
Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPL 434

Query: 180 R---PMMPQKVQLEVGRP--QAPLNSFHAAKK--PPNQSLPLQPFQLAFGHQVNRQVFRQ 232
               P++P   +  +  P  ++P +    A +  PP + LP  P   A    ++R +  +
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL--HLSRPL-EE 491

Query: 233 GP--PPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGL 290
            P  PPP      PP +       ++         P  P  E   S P + S     F  
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551

Query: 291 QPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLS 350
            P  P  +              P P+ +P          +P P   ++  PF        
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF-------- 603

Query: 351 KEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLL 410
           +E  L P   +   + P + +  +      P+  PP  S   P PE          S+L 
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663

Query: 411 PDGERLAPNGREREAPAMGSEEGMRA------VSTGDCGQVLRGGVIQSTRRRRRASQEA 464
           P  E    +    E+P     E  R         T    +                 +E+
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723

Query: 465 NLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVP 524
            LL L ++       +        EE   S          +  EP L+ +        VP
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783

Query: 525 LIIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTD---AQ 581
               +S        +   +   L    + P  +P   +P +      S   P ++     
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843

Query: 582 AQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLA 641
            + E+ ++     P + KP   PRPE    P + G   AP       P      SP  L 
Sbjct: 844 PRPEESHL----SPELEKPPLSPRPEK--PPEEPGQCPAPEELPLFPPPGEPSLSP--LL 895

Query: 642 DHPSERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSA 701
             P+      PP +P P   P+        +  +     P PPP++P       + T +A
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD-PLPPPLSP-------IITAAA 947

Query: 702 EVTPPVLSVMGE 713
              PP LS +GE
Sbjct: 948 ---PPALSPLGE 956



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 35/99 (35%), Positives = 46/99 (46%), Gaps = 6/99 (6%)

Query: 228  QVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQD 287
            QV +Q     N +A +   KQQQQQQ QQQQQQQ +A+  +   ++   + + P Q    
Sbjct: 3580 QVRKQQKEHTNLMAEYR-NKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPG 3638

Query: 288  FGLQ-----PAGPLGQSHLAHHSMAPYPFPPNPDMNPEL 321
             GLQ     P G  G   L    MA    P  P +N  L
Sbjct: 3639 HGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTAL 3677



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 94/407 (23%), Positives = 140/407 (34%), Gaps = 97/407 (23%)

Query: 19   GGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVY 78
            GG+   P   PPP    ++++ VK+E+ LG   P              P +L  ++S   
Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEE-LGASSPSYG-----------PPNLGFVDSPSS 2312

Query: 79   GPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHS 138
            G       + +  V   K P +  A    P+  G G         +P +PPP        
Sbjct: 2313 GTHLGGLELKTPDV--FKAPLTPRASQVEPQSPGLG--------LRPQEPPP-------- 2354

Query: 139  LSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPL 198
                 A   +P P        +HP+  +     G   D Y +P +         RPQ P 
Sbjct: 2355 -----AQALAPSPP-------SHPDIFR----PGSYTDPYAQPPL-------TPRPQPPP 2391

Query: 199  NSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVA--AFPPQKQQQQQQPQQ 256
                 A  P  +SLP  PF          Q   Q P  P P++  AF P        P+ 
Sbjct: 2392 PESCCALPP--RSLPSDPFS-RVPASPQSQSSSQSPLTPRPLSAEAFCP----SPVTPRF 2444

Query: 257  QQQQQQAALPQMPLFEN-FYSMPQQPSQQPQDFGLQ------------------PAGPLG 297
            Q     +  P  P   + F  + + P  QP +   +                  PAGP G
Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504

Query: 298  QSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPP 357
            +     H+  P   PPN   +P     +   S  +   PQ  +  P     + + G+ PP
Sbjct: 2505 EL----HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQA-VGEPSLKPPVPQPGLPPP 2559

Query: 358  SALD---GAGTQPGQE-------ATGNLFLHHWPLQQPPPGSLGQPH 394
              ++   G G   G+        ATGN      PL  P  GS G+ +
Sbjct: 2560 HGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPL-GPSSGSTGESY 2605



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 73/288 (25%), Positives = 103/288 (35%), Gaps = 32/288 (11%)

Query: 24   APKEQPPPLQPPQQS-----IRVKEEQYLGHEGPGGAVSTSQ-----PVELPPPSSLA-- 71
            A K Q    Q  QQ      + ++++Q    +GPG  V T+Q     P  L PPSS    
Sbjct: 3731 AQKLQQQQQQQQQQQHLLGQVAIQQQQ---QQGPG--VQTNQALGPKPQGLMPPSSHQGL 3785

Query: 72   LLNSVVYGPERTSAAMLSQ-QVASVKWPNSVMAPGRGPERG---GGGGVSDSSWQQQPGQ 127
            L+  +   P +    ML   QVA ++  +      +GP R        V  S    Q GQ
Sbjct: 3786 LVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQ 3845

Query: 128  PPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKV 187
                       ++     +   H   G     +H +      +G P+L       + Q  
Sbjct: 3846 ----GLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQ 3901

Query: 188  QLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQK 247
            Q +  + Q  L      +    Q L  Q  Q     Q  +Q  +Q             Q+
Sbjct: 3902 QQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ-------QQ 3954

Query: 248  QQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGP 295
             QQQQQ QQQQ QQQ    QM L     ++     QQ Q   L P  P
Sbjct: 3955 LQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMP 4002



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 97/375 (25%), Positives = 129/375 (34%), Gaps = 73/375 (19%)

Query: 228  QVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQD 287
            Q F Q  P P  +       QQQQQQ  QQQQ   A   +  +   F      PS    +
Sbjct: 2796 QAFYQRAPYPGSLPL-----QQQQQQLWQQQQATAATSMRFAMSARF------PSTPGPE 2844

Query: 288  FGLQPAG-PL-GQSHLAHHSMAPYPFPPNPDMNPELR----KALLQDSAPQPALPQVQ-- 339
             G Q  G PL G S        P P P  P    ELR    K L     P P     Q  
Sbjct: 2845 LGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRP 2904

Query: 340  --IPFPRRSRRLSKEGI--------------LPPSALDGAGTQPGQEATGNLFLHHWPLQ 383
               P      RL+ EG+               PP+        P     G        L 
Sbjct: 2905 RFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELV 2964

Query: 384  QPPPGS--LGQPHP---EALGFPLELRE-------SQLLPDGERLAPNGREREAPAMGSE 431
              PP S  LG+P+P   EA   P E  E        + L D E LA  G   +      E
Sbjct: 2965 NRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDE 3024

Query: 432  EG-MRAVSTGD--CGQVLRGG----------VIQSTRRRRRASQEANLLTLA-QKAVELA 477
             G +  + T D     +L G            + +  ++   ++   L+  A +KA   A
Sbjct: 3025 LGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREA 3084

Query: 478  SLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLAT-----KRAREDSGMVPLIIPVSVP 532
             L+  + G    E+R    A       + SEP LA+     K   E+ G  P     ++ 
Sbjct: 3085 LLRGVEPGPLGPEERPPPAA-------DASEPRLASVLPEVKPKVEEGGRHPSPCQFTIA 3137

Query: 533  VRTVDPTEAAQAGGL 547
               V+P  AA + GL
Sbjct: 3138 TPKVEPAPAANSLGL 3152



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 154/726 (21%), Positives = 242/726 (33%), Gaps = 133/726 (18%)

Query: 17   LFGGQEPAPKEQPP---PLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPP----SS 69
            LF   E +P   PP   PL PP ++ R+        + P        P+  PP     S 
Sbjct: 599  LFPPFEESPLSPPPEESPLSPPPEASRLSPPP---EDSPMSPPPEESPMSPPPEVSRLSP 655

Query: 70   LALLNSVVYGPERTSAAMLSQQVASVKWPN-SVMAPGRGPERGGGGGVSDSSWQQQPGQP 128
            L +++ +   PE +  +   ++  +   P  S ++P   PE        + S    P  P
Sbjct: 656  LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP--PEDSPTSPPPEDS----PASP 709

Query: 129  PPHSTWNCHSLS------------LYSATKGSPH--PGVGVPTYYNHPEALKREKAGGPQ 174
            PP  +     L             L   ++G PH  P    P     PE    E    PQ
Sbjct: 710  PPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLSPRPEEPHLSPRPE----EPHLSPQ 764

Query: 175  LDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGP 234
             +       P++  L    P+ P    H + +     L  QP +L    Q         P
Sbjct: 765  AEEPHLSPQPEEPCL-CAVPEEP----HLSPQAEGPHLSPQPEELHLSPQTEEP--HLSP 817

Query: 235  PPPNPVAA-------FPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQD 287
             P  P  +         PQ ++    P+ ++      L + PL       P++P Q P  
Sbjct: 818  VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP-- 875

Query: 288  FGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALP-QVQIPF---- 342
                          A   +  +P P  P ++P L +  L +    P  P   ++P     
Sbjct: 876  --------------APEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921

Query: 343  -PRRSRRLSKEGILPP--SALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEA-- 397
             P  S +L     LPP  S +  A   P     G L        + P G+ G   PE+  
Sbjct: 922  EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL--------EYPFGAKGDSDPESPL 973

Query: 398  ----LGFPLELRESQLLPDGERLAPNGREREAPAMGSEEG-----MRAVSTGDCGQVLRG 448
                L  P+         D E + P       P+ GS  G     +       C  +L+ 
Sbjct: 974  AAPILETPISPPPEANCTDPEPVPP---MILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030

Query: 449  GVIQSTRRRRRASQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSE 508
             ++       + S  A  L++      +  +    D +   E  ++   S  +C     E
Sbjct: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE-METEKVSEPECPA--LE 1087

Query: 509  PSLATKRAREDSGMVPLIIPVSVPVRTVDP-----TEAAQAGGLDEDGKGPE--QNP--- 558
            PS  +      S M  L  P   P   +D       + A   G+D  G  PE  Q P   
Sbjct: 1088 PSATSPL---PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSL 1144

Query: 559  -AEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGT 617
             +E K S ++        P T  +   E      +G P     +++  P   + PT   T
Sbjct: 1145 ASELKGSPVLLDPEEL-APVTPMEVYPECKQTAGQGSPC----EEQEEPRAPVAPTPP-T 1198

Query: 618  FIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSG-LYFNAIIS 676
             I   + + I+           L+   +  SF   P + P + SP  EG G L     +S
Sbjct: 1199 LIKSDIVNEIS----------NLSQGDASASF---PGSEPLLGSPDPEGGGSLSMELGVS 1245

Query: 677  TSTIPA 682
            T   PA
Sbjct: 1246 TDVSPA 1251



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 71/272 (26%), Positives = 88/272 (32%), Gaps = 67/272 (24%)

Query: 147  GSPHPGVGVPTYYNHPEALKREKAG-------GPQLDRYVRPMMPQKVQLEVGRPQAPLN 199
            GS      VP     P     ++ G       GPQ     +PM+ + +Q   G PQ P  
Sbjct: 4122 GSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ-----QPMLERPMQNNTG-PQPP-- 4173

Query: 200  SFHAAKKP-----PNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAF--PPQKQQQQQ 252
                  KP       Q LP        G Q+  Q+  QG    NP      P Q+QQ Q 
Sbjct: 4174 ------KPGPVLQSGQGLPGVGIMPTVG-QLRAQL--QGVLAKNPQLRHLSPQQQQQLQA 4224

Query: 253  QPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQD----FGLQP---------AGPLGQS 299
               Q+Q QQ  A+ Q P +       Q+P  Q        G QP          GPL + 
Sbjct: 4225 LLMQRQLQQSQAVRQTPPY-------QEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQEL 4277

Query: 300  HLAHHSMAPYPFPPNP---DMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILP 356
                    P   P  P      P L           P  P+     P  S +L  E  LP
Sbjct: 4278 GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP 4337

Query: 357  PSALDGAGTQPGQEATGNLFLHHWPLQQPPPG 388
            P       T PG            P  +PPPG
Sbjct: 4338 P-------THPGTPKP------QGPTLEPPPG 4356



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 35/116 (30%), Positives = 46/116 (39%), Gaps = 8/116 (6%)

Query: 329  SAPQPALPQVQIPFPRRSRRLSK--EGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPP 386
            S P  A P + I  P     LS   +G L P A    G+ PG ++ G LFL   P Q P 
Sbjct: 2115 SPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPA----GSVPGPDSPGELFL-KLPPQVPA 2169

Query: 387  PGSLGQPHPEALGFPLELRESQLLPDGERL-APNGREREAPAMGSEEGMRAVSTGD 441
                  P   A  +PLE R     P      +P G   + P +G+     A   G+
Sbjct: 2170 QVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGE 2225



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 37/95 (38%), Positives = 42/95 (44%), Gaps = 11/95 (11%)

Query: 246  QKQQQ---QQQP--QQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSH 300
            QK+QQ   Q QP  QQQQQQQQ +L   P      S+P + S  P   G Q    LG   
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGS-SPSLAGSQQQLSLG--- 3316

Query: 301  LAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPAL 335
            LA       P P  P   P    AL Q  AP  A+
Sbjct: 3317 LAGARQPGLPQPLMPTQPP--AHALQQRLAPSMAM 3349


>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
          Length = 449

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%)

Query: 723 INVGSRFQAEIPLMRDRALAAADPHKAD-LVWQPWEDLESSREKQRQVEDLLTAACSSIF 781
           + VG+ +QA IP     A    D      LVW P+  +  ++     +++ +  A     
Sbjct: 59  MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAK-----LDEYIAIAKEK-- 111

Query: 782 PGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLF 841
              G N E AL  L   + +I ++L  L       P+  P         D+W + ++ LF
Sbjct: 112 --HGYNVEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKVLF 155

Query: 842 NKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKK 876
            +  + + K F  +Q+++  KT+A  V++YY++KK
Sbjct: 156 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 15/49 (30%), Positives = 26/49 (53%)

Query: 832 QWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKI 880
           +W   E+ L  +G+  Y KDF  +  +I  KTV Q   F+  Y+++  +
Sbjct: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNL 395


>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
          Length = 553

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%)

Query: 723 INVGSRFQAEIPLMRDRALAAADPHKAD-LVWQPWEDLESSREKQRQVEDLLTAACSSIF 781
           + VG+ +QA IP     A    D      LVW P+  +  ++     +++ +  A     
Sbjct: 59  MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAK-----LDEYIAIAKEK-- 111

Query: 782 PGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLF 841
              G N E AL  L   + +I ++L  L       P+  P         D+W + ++ LF
Sbjct: 112 --HGYNVEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKVLF 155

Query: 842 NKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKK 876
            +  + + K F  +Q+++  KT+A  V++YY++KK
Sbjct: 156 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 23/114 (20%)

Query: 832 QWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKI--------GRN 883
           +W   E+ L  +G+  Y KDF  +  +I  KTV Q   F+  Y+++  +           
Sbjct: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406

Query: 884 GT-LTFGDVDTSDE-----------KSAQEEVEVDIKTSQKFPRVPLPRRESPS 925
           GT  + GD  T  E           KS  EE E     + + PR   P   +PS
Sbjct: 407 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQ---TPQAPRTLGPSPPAPS 457


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,235,038
Number of Sequences: 37866
Number of extensions: 3239187
Number of successful extensions: 28845
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 307
Number of HSP's successfully gapped in prelim test: 770
Number of HSP's that attempted gapping in prelim test: 17014
Number of HSP's gapped (non-prelim): 6893
length of query: 1045
length of database: 18,247,518
effective HSP length: 113
effective length of query: 932
effective length of database: 13,968,660
effective search space: 13018791120
effective search space used: 13018791120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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