BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|103472003 forkhead box O4 [Homo sapiens] (505 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|103472003 forkhead box O4 [Homo sapiens] 1025 0.0 gi|42519916 forkhead box O3A [Homo sapiens] 352 3e-97 gi|4503739 forkhead box O3A [Homo sapiens] 352 3e-97 gi|9257222 forkhead box O1 [Homo sapiens] 338 7e-93 gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens] 311 1e-84 gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens] 269 4e-72 gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] 190 3e-48 gi|208431824 forkhead box I3 [Homo sapiens] 95 1e-19 gi|4885237 forkhead box C2 [Homo sapiens] 90 4e-18 gi|32307177 forkhead box G1 [Homo sapiens] 87 4e-17 gi|50345831 forkhead box J3 [Homo sapiens] 86 8e-17 gi|134142824 forkhead box D2 [Homo sapiens] 85 1e-16 gi|21618327 forkhead box I1 isoform a [Homo sapiens] 83 7e-16 gi|195947376 forkhead box I2 [Homo sapiens] 82 9e-16 gi|145309320 forkhead box Q1 [Homo sapiens] 81 2e-15 gi|8923842 forkhead box J2 [Homo sapiens] 81 2e-15 gi|119395716 forkhead box C1 [Homo sapiens] 80 6e-15 gi|24497506 forkhead box A3 [Homo sapiens] 79 7e-15 gi|21618325 forkhead box E1 [Homo sapiens] 79 1e-14 gi|4758392 forkhead box D1 [Homo sapiens] 79 1e-14 gi|28973785 forkhead box S1 [Homo sapiens] 77 3e-14 gi|31563338 forkhead box K2 [Homo sapiens] 76 6e-14 gi|22779860 forkhead box L1 [Homo sapiens] 75 1e-13 gi|4557595 forkhead box F2 [Homo sapiens] 75 2e-13 gi|105554437 forkhead box B1 [Homo sapiens] 75 2e-13 gi|24497501 forkhead box A1 [Homo sapiens] 74 4e-13 gi|110735445 forkhead box F1 [Homo sapiens] 74 4e-13 gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens] 74 4e-13 gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens] 74 4e-13 gi|6912372 forkhead box D3 [Homo sapiens] 73 5e-13 >gi|103472003 forkhead box O4 [Homo sapiens] Length = 505 Score = 1025 bits (2650), Expect = 0.0 Identities = 505/505 (100%), Positives = 505/505 (100%) Query: 1 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT 60 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT Sbjct: 1 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT 60 Query: 61 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK 120 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK Sbjct: 61 EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK 120 Query: 121 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML 180 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML Sbjct: 121 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML 180 Query: 181 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG 240 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG Sbjct: 181 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG 240 Query: 241 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL 300 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL Sbjct: 241 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL 300 Query: 301 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF 360 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF Sbjct: 301 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF 360 Query: 361 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE 420 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE Sbjct: 361 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE 420 Query: 421 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE 480 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE Sbjct: 421 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE 480 Query: 481 CDMDNIISDLMDEGEGLDFNFEPDP 505 CDMDNIISDLMDEGEGLDFNFEPDP Sbjct: 481 CDMDNIISDLMDEGEGLDFNFEPDP 505 >gi|42519916 forkhead box O3A [Homo sapiens] Length = 673 Score = 352 bits (904), Expect = 3e-97 Identities = 243/646 (37%), Positives = 328/646 (50%), Gaps = 177/646 (27%) Query: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEVEPD------------ 53 ++LDP+FEPQSRPRSCTWPL RPE+ P++P PE E D Sbjct: 16 VELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGS 75 Query: 54 ------------LGEKVHTE-------------------------GRSEPILLPSRLPEP 76 LG + E G ++ +L P +P Sbjct: 76 AMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQ---QP 132 Query: 77 AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136 PQPG G PRK SRRNAWGN SYA+LI++AIES+P+KRLTL+QIYEWMVR VP Sbjct: 133 LPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVP 192 Query: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAA 196 YFKDKGDSNSSAGWKNSIRHNLSLHS+F++V NE TGKSSWW++NP+GGKSGKAPRRRA Sbjct: 193 YFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAV 252 Query: 197 SMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTF 256 SMD+S+K + R +A KKK ++ AP + SP +KW GSP SR+ +E D WT F Sbjct: 253 SMDNSNKYTKSRGRAAKKKAALQTAPE--SADDSP-SQLSKWPGSPTSRSSDELDAWTDF 309 Query: 257 RPRSSSNASSVSTRLSPLRPES---EVLAEEIPASVSSYAGGV--------PPT------ 299 R R++SNAS+VS RLSP+ + EV ++ P S Y+ P T Sbjct: 310 RSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRL 369 Query: 300 --------LNEGL------ELLDGLNLTSSH-----SLLSRSGLSGFSLQHPGVTGPLHT 340 LN+GL +LLD + L S L+ RS ++ + G+ P + Sbjct: 370 TDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSS 429 Query: 341 YSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLTSDTPPPPADVLMTQ 385 ++S++F P+ + P+ + FSS +Q L+ LLTSD+ +DV+MTQ Sbjct: 430 FNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDS-LSHSDVMMTQ 488 Query: 386 VDPILSQAPTLL------------------------------------------LLGGLP 403 DP++SQA T + LGG Sbjct: 489 SDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSR 548 Query: 404 SSSKLATGVGL-------CPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTP 456 + S + +GL K + S + TLS + S+ + PV+ Sbjct: 549 ALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLS----DSLSGSSLYSTSANLPVM-- 602 Query: 457 PTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFE 502 ++ P DLDLDM+ +LECDM++II + + +GLDFNF+ Sbjct: 603 -----GHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFD 643 >gi|4503739 forkhead box O3A [Homo sapiens] Length = 673 Score = 352 bits (904), Expect = 3e-97 Identities = 243/646 (37%), Positives = 328/646 (50%), Gaps = 177/646 (27%) Query: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEVEPD------------ 53 ++LDP+FEPQSRPRSCTWPL RPE+ P++P PE E D Sbjct: 16 VELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGS 75 Query: 54 ------------LGEKVHTE-------------------------GRSEPILLPSRLPEP 76 LG + E G ++ +L P +P Sbjct: 76 AMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQ---QP 132 Query: 77 AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136 PQPG G PRK SRRNAWGN SYA+LI++AIES+P+KRLTL+QIYEWMVR VP Sbjct: 133 LPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVP 192 Query: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAA 196 YFKDKGDSNSSAGWKNSIRHNLSLHS+F++V NE TGKSSWW++NP+GGKSGKAPRRRA Sbjct: 193 YFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAV 252 Query: 197 SMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTF 256 SMD+S+K + R +A KKK ++ AP + SP +KW GSP SR+ +E D WT F Sbjct: 253 SMDNSNKYTKSRGRAAKKKAALQTAPE--SADDSP-SQLSKWPGSPTSRSSDELDAWTDF 309 Query: 257 RPRSSSNASSVSTRLSPLRPES---EVLAEEIPASVSSYAGGV--------PPT------ 299 R R++SNAS+VS RLSP+ + EV ++ P S Y+ P T Sbjct: 310 RSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRL 369 Query: 300 --------LNEGL------ELLDGLNLTSSH-----SLLSRSGLSGFSLQHPGVTGPLHT 340 LN+GL +LLD + L S L+ RS ++ + G+ P + Sbjct: 370 TDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSS 429 Query: 341 YSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLTSDTPPPPADVLMTQ 385 ++S++F P+ + P+ + FSS +Q L+ LLTSD+ +DV+MTQ Sbjct: 430 FNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDS-LSHSDVMMTQ 488 Query: 386 VDPILSQAPTLL------------------------------------------LLGGLP 403 DP++SQA T + LGG Sbjct: 489 SDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSR 548 Query: 404 SSSKLATGVGL-------CPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTP 456 + S + +GL K + S + TLS + S+ + PV+ Sbjct: 549 ALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLS----DSLSGSSLYSTSANLPVM-- 602 Query: 457 PTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFE 502 ++ P DLDLDM+ +LECDM++II + + +GLDFNF+ Sbjct: 603 -----GHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFD 643 >gi|9257222 forkhead box O1 [Homo sapiens] Length = 655 Score = 338 bits (867), Expect = 7e-93 Identities = 254/638 (39%), Positives = 327/638 (51%), Gaps = 153/638 (23%) Query: 11 EAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQ--------PSEPPEVEPDL-------- 54 EA ++++DPDFEP RPRSCTWPLPRPE + PS PD Sbjct: 3 EAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSAS 62 Query: 55 GEKVHTEGRSEPILLPSR--LPEPAG-----------------------GPQPGIL---- 85 V + S LL P+ G GP+ G L Sbjct: 63 AAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAP 122 Query: 86 ----------------GAVTGPRKG------GSRRNAWGNQSYAELISQAIESAPEKRLT 123 A GP G SRRNAWGN SYA+LI++AIES+ EKRLT Sbjct: 123 PQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLT 182 Query: 124 LAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPE 183 L+QIYEWMV++VPYFKDKGDSNSSAGWKNSIRHNLSLHSKFI+V NE TGKSSWWMLNPE Sbjct: 183 LSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPE 242 Query: 184 GGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPC 243 GGKSGK+PRRRAASMD++SK + RS+A KKK S L + EGA SP F+KW SP Sbjct: 243 GGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKAS-LQSGQEGA-GDSPGSQFSKWPASPG 300 Query: 244 SRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAE------EIPASVSSYAGGVP 297 S + ++ D W+TFRPR+SSNAS++S RLSP+ E + L E P S + A +P Sbjct: 301 SHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLP 360 Query: 298 PTLN----EGLE-LLDGLNLTSSHSLLSRSGLS-----------------GFSLQHPGVT 335 E +E LLD LNL SS + L+ S S SL P Sbjct: 361 SLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPN 420 Query: 336 GPLHTYSSSLFSP-AEGPLSAGEGCFSS----SQ------ALEALLTSDTPPPPADVLMT 384 +TY S SP + P+ + SS SQ L+ LLTSD+ PP + +MT Sbjct: 421 YQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDS--PPHNDIMT 478 Query: 385 QVDPILSQAPTLLLLGGL----PSS------SKLATGVGLCPKPLEAPGPSSLVPTLSMI 434 VDP ++Q P +LG P+S S+ + + P PG + ++ Sbjct: 479 PVDPGVAQ-PNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGR 537 Query: 435 APPPVMASAPIPKALG------TPVLTP---PTEAAS--------------------QDR 465 P +++ P + TPV P P + ++ Q++ Sbjct: 538 PLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEK 597 Query: 466 MPQDLDLDMYMENLECDMDNII-SDLMDEGEGLDFNFE 502 +P DLD M++E L+CDM++II +DLMD G+ LDFNF+ Sbjct: 598 LPSDLD-GMFIERLDCDMESIIRNDLMD-GDTLDFNFD 633 >gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens] Length = 492 Score = 311 bits (796), Expect = 1e-84 Identities = 209/504 (41%), Positives = 263/504 (52%), Gaps = 61/504 (12%) Query: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75 +D+DPDF PQSRPRSCTWPLP+P++A E + + E G P+ P Sbjct: 10 VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67 Query: 76 PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133 P LGA GP + SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR Sbjct: 68 PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 Query: 134 TVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRR 193 VPYFKDKGDSNSSAGWKNSIRHNLSLH++FI+V NE TGKSSWWMLNPEGGK+GK PRR Sbjct: 121 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 180 Query: 194 RAASMDSSSKLLRGRSKAPKKKPSVLP-APPEGATPTS----PVGHFAKWSGSPCSRNRE 248 RA SMD+ +K LR + KA KKK P P+ ++P++ PV AKW+ SP S + Sbjct: 181 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 240 Query: 249 EADMWTTFRPRSSSNASSVSTRLSPLRPES--EVLAEEIPASVSSYAGGVPPTLNEGL-- 304 + + W FR + + L + E LA P S A + P L Sbjct: 241 DYEAWADFR----GGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPG 296 Query: 305 ELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCFSSSQ 364 EL L L G G L + G Y +P GP+ G + + Sbjct: 297 EL---PRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRP-APRPGPVLGAPGELALAG 352 Query: 365 ALEALLTSDTPP--PPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAP 422 A A P PPA PS S LA + L P EA Sbjct: 353 AAAAYPGKGAAPYAPPA-----------------------PSRSALAHPISLMTLPGEA- 388 Query: 423 GPSSLVP---TLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENL 479 G + L P + PP + +P P A+ DR P DLDLDM+ +L Sbjct: 389 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGP--LGAAPDRFPADLDLDMFSGSL 446 Query: 480 ECDMDNII-SDLMDEGEGLDFNFE 502 ECD+++II +D MD E +DFNF+ Sbjct: 447 ECDVESIILNDFMDSDE-MDFNFD 469 >gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens] Length = 562 Score = 269 bits (688), Expect = 4e-72 Identities = 139/249 (55%), Positives = 170/249 (68%), Gaps = 16/249 (6%) Query: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75 +D+DPDF PQSRP S TWPLP+P++A E + + E G P+ P Sbjct: 187 VDVDPDFAPQSRPHSSTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 244 Query: 76 PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133 P LGA GP + SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR Sbjct: 245 PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 297 Query: 134 TVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRR 193 VPYFKDKGDSNSSAGWKNSIRHNLSLH++FI+V NE TGKSSWWMLNPEGGK+GK PRR Sbjct: 298 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 357 Query: 194 RAASMDSSSKLLRGRSKAPKKKPSVLP-APPEGATPTS----PVGHFAKWSGSPCSRNRE 248 RA SMD+ +K LR + KA KKK P P+ ++P++ PV AKW+ SP S + Sbjct: 358 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 417 Query: 249 EADMWTTFR 257 + + W FR Sbjct: 418 DYEAWADFR 426 >gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] Length = 589 Score = 190 bits (482), Expect = 3e-48 Identities = 185/588 (31%), Positives = 253/588 (43%), Gaps = 132/588 (22%) Query: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75 +D+DPDF PQSRPRSCTWPLP+P++A E + + E G P+ P Sbjct: 10 VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67 Query: 76 PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133 P LGA GP + SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR Sbjct: 68 PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 Query: 134 TVPYFKDKGDSNSSAGWKNSI---------RHNLSLHSKFIKVHNEATGKSSWWMLNPEG 184 VPYFKDKGDSNSSAGWK R L ++ + + G+ L P G Sbjct: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQE---GRQKEGFLAPPG 177 Query: 185 ---GKSGKAPRRRAASMDSSSKLLRGRSKAPKKK-------PSV-------LPAPPEGAT 227 S +AP SSS +LRG S AP+ P V L P+ Sbjct: 178 VTESCSSRAP--------SSSFVLRG-SPAPRADGGGEVTFPEVATCEVVDLGIGPQARA 228 Query: 228 PTSPVGHFAKWSGSPCSRNRE--EADMWTTFRPRSSSNASSVSTRLSP--------LRPE 277 + P+G + G+ + E W F P S+++ S+ ++ + + Sbjct: 229 FSVPLGASLQGWGTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQ 288 Query: 278 SEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLS----------------- 320 E E + + A G+P LN+GL+ S L S Sbjct: 289 EEAWTENLNFTPDGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESD 348 Query: 321 ----------------RSGLSGFSLQHPGVTGPLHT--------YSSSLFSPAEGPLSAG 356 R+GL+ G TG H+ + +F G + Sbjct: 349 QCLELGQYLDQEVEATRTGLAKAG-SDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATH 407 Query: 357 EGCFSSSQALEALLTSDT--PPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGL 414 G F + L PPPPA + P+L AP L L G ++ G G Sbjct: 408 CGDFEKAPTARGLEGRQVVPPPPPA----PRPGPVLG-APGELALAG---AAAAYPGKGA 459 Query: 415 CPKPLEAPGPSSLVPTLSMIAPPPVMASAPI------------PKALGTPVLTPPTEA-- 460 P AP S+L +S++ P +A + P L L P A Sbjct: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519 Query: 461 -----ASQDRMPQDLDLDMYMENLECDMDNII-SDLMDEGEGLDFNFE 502 A+ DR P DLDLDM+ +LECD+++II +D MD E +DFNF+ Sbjct: 520 AGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDE-MDFNFD 566 >gi|208431824 forkhead box I3 [Homo sapiens] Length = 420 Score = 95.1 bits (235), Expect = 1e-19 Identities = 108/362 (29%), Positives = 162/362 (44%), Gaps = 69/362 (19%) Query: 34 PLPRPEIANQPS-EPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGILGAVTGPR 92 P P P A P +PP G + P P+ PAG PG LG ++ Sbjct: 81 PPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAA-PASPAAPAG---PGELGWLSMAS 136 Query: 93 KGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKN 152 + + SY+ LI+ AI+SAPE++LTL+ IY+++ + P+++ S AGW+N Sbjct: 137 REDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQ-----RSKAGWQN 191 Query: 153 SIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGK-----SGKAPRRRAASMDSSSKLL 205 SIRHNLSL+ F KV + GK ++W L+P K + + R+R + + S + Sbjct: 192 SIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASNGSTVA 251 Query: 206 RGRSKAPK----------------------KKPSVLPAPPEG--ATPTSPVGHFAKWSGS 241 G SK+ + +PS P PPEG +T +SP G + + Sbjct: 252 AGTSKSEEGLSSGLGSGVGGKPEEESPSTLLRPSHSPEPPEGTKSTASSPGGPML--TST 309 Query: 242 PCSRNREEADMWTTFRPRSS-SNASSVST-RLSPLRPESEVLAEEIPASVSSYAGGV--P 297 PC + T F SS S +SSVST R P + ++P+S GV P Sbjct: 310 PC--------LNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSS------GVFSP 355 Query: 298 PTLNE-GLELLDGLNLTSSHSLLSRSGLSGFSLQHPG-----VTGPLHTYS--SSLFSPA 349 +++E + L N TS+ + S S F G + P H +S +SL P Sbjct: 356 TSISEASADTLQLSNSTSNSTGQRSSYYSPFPASTSGGQSSPFSSPFHNFSMVNSLIYPR 415 Query: 350 EG 351 EG Sbjct: 416 EG 417 >gi|4885237 forkhead box C2 [Homo sapiens] Length = 501 Score = 90.1 bits (222), Expect = 4e-18 Identities = 80/264 (30%), Positives = 125/264 (47%), Gaps = 57/264 (21%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY LI+ AI++APEK++TL IY++++ P++++ + GW+NSIRHNLSL+ F Sbjct: 76 SYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRE-----NKQGWQNSIRHNLSLNECF 130 Query: 165 IKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSV---- 218 +KV ++ GK S+W L+P+ + +M + LR R + KK S Sbjct: 131 VKVPRDDKKPGKGSYWTLDPD-----------SYNMFENGSFLRRRRRFKKKDVSKEKEE 179 Query: 219 ---LPAPPEGATPTSP-VGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPL 274 L PP A+ +P H A +P +EA+ + ++S A V T++ L Sbjct: 180 RAHLKEPPPAASKGAPATPHLA---DAP-----KEAEKKVVIKSEAASPALPVITKVETL 231 Query: 275 RPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGV 334 PES + + P S +S G P DG H + +GL GFS+++ Sbjct: 232 SPESAL--QGSPRSAASTPAGSP----------DG--SLPEHHAAAPNGLPGFSVEN--- 274 Query: 335 TGPLHTYSSSLFSPAEGPLSAGEG 358 + SP G LS G G Sbjct: 275 ------IMTLRTSPPGGELSPGAG 292 >gi|32307177 forkhead box G1 [Homo sapiens] Length = 489 Score = 87.0 bits (214), Expect = 4e-17 Identities = 71/227 (31%), Positives = 94/227 (41%), Gaps = 70/227 (30%) Query: 34 PLPRPEIANQPSEPPEVEPDLGEKVHTEGRS--------EPILLPSRLP----------- 74 P P+P Q +PP P + T G + +LLP P Sbjct: 61 PAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAK 120 Query: 75 --------EPAGGPQPGILGAV------TGPRKGGSRRNAWGNQ---------------- 104 EP GGP G L V G GG + G Sbjct: 121 ADGLGGKGEPGGGP--GELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGK 178 Query: 105 ------SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNL 158 SY LI AI +PEKRLTL IYE++++ PY+++ + GW+NSIRHNL Sbjct: 179 YEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRE-----NKQGWQNSIRHNL 233 Query: 159 SLHSKFIKV--HNEATGKSSWWMLNPE------GGKSGKAPRRRAAS 197 SL+ F+KV H + GK ++WML+P GG +GK RR S Sbjct: 234 SLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTS 280 >gi|50345831 forkhead box J3 [Homo sapiens] Length = 622 Score = 85.9 bits (211), Expect = 8e-17 Identities = 44/102 (43%), Positives = 68/102 (66%), Gaps = 9/102 (8%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SYA LI+ AI S+P+K++TL++IY+W+ PY+++ G +GWKNSIRHNLSL+ F Sbjct: 82 SYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAG-----SGWKNSIRHNLSLNKCF 136 Query: 165 IKV--HNEATGKSSWWML--NPEGGKSGKAPRRRAASMDSSS 202 +KV + GK S+W + NP+ P++RA S++ +S Sbjct: 137 LKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERAS 178 >gi|134142824 forkhead box D2 [Homo sapiens] Length = 495 Score = 85.1 bits (209), Expect = 1e-16 Identities = 84/265 (31%), Positives = 118/265 (44%), Gaps = 52/265 (19%) Query: 7 NSATEAAAIIDLDPDFE------------PQSRPRSCTWPLPRPEIANQPSEPP--EVEP 52 +S + AA+ + D D + +S PR+ PR ++ EPP E E Sbjct: 12 SSESSPAALSEADADIDVVGGGSGGGELPARSGPRA-----PR-DVLPHGHEPPAEEAEA 65 Query: 53 DLGEKVHTEGR---SEPILLPSR-LPEPAGGPQPGIL------GAVTGPRKGGSRRNA-- 100 DL E G EP L SR AG P PG G GP GG+ + Sbjct: 66 DLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPL 125 Query: 101 -WGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLS 159 SY LI+ AI +P+KRLTL++I E++ PY+++K W+NSIRHNLS Sbjct: 126 VKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREK-----FPAWQNSIRHNLS 180 Query: 160 LHSKFIKVHNEA--TGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPS 217 L+ F+K+ E GK ++W L+PE +A M + LR R K K++P Sbjct: 181 LNDCFVKIPREPGNPGKGNYWTLDPE-----------SADMFDNGSFLR-RRKRFKRQPL 228 Query: 218 VLPAPPEGATPTSPVGHFAKWSGSP 242 P P P + A +G P Sbjct: 229 PPPHPHPHPHPELLLRGGAAAAGDP 253 >gi|21618327 forkhead box I1 isoform a [Homo sapiens] Length = 378 Score = 82.8 bits (203), Expect = 7e-16 Identities = 58/156 (37%), Positives = 80/156 (51%), Gaps = 22/156 (14%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY+ LI+ AI AP+KRLTL+QIY+++ P++ + S AGW+NSIRHNLSL+ F Sbjct: 127 SYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFY-----NKSKAGWQNSIRHNLSLNDCF 181 Query: 165 IKV--HNEATGKSSWWMLNPEGGK---SGKAPRRRAASMDSSSK-----LLRGRSKAPKK 214 KV + GK ++W L+P K +G R+R D SS L + S P Sbjct: 182 KKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVD 241 Query: 215 KP------SVLPAPPEGATPTSPVGH-FAKWSGSPC 243 P +L G T +SP SG+PC Sbjct: 242 SPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPC 277 >gi|195947376 forkhead box I2 [Homo sapiens] Length = 318 Score = 82.4 bits (202), Expect = 9e-16 Identities = 72/230 (31%), Positives = 108/230 (46%), Gaps = 31/230 (13%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY+ LI+ AI+SAP ++LTL+QIY+++ P++K S AGW+NSIRHNLSL+ F Sbjct: 106 SYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYK-----RSKAGWQNSIRHNLSLNDCF 160 Query: 165 IKV--HNEATGKSSWWMLNPEGGK---SGKAPRRRAASMDSSSKLLRG-RSKAPKKKPSV 218 KV + GK ++W L+P K +G R+R ++S+ + G RS + P++ Sbjct: 161 KKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPAL 220 Query: 219 LPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPES 278 P P SP E A ++ F S+ A + T P Sbjct: 221 EP----------PSAACLDLQASPSPSAPEAATCFSGFASAMSALAGGLGT--FPGGLAG 268 Query: 279 EVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTS-----SHSLLSRSG 323 + P +V+++A P TLN G + SH L SR G Sbjct: 269 DFSFGRRPPTVATHA---PQTLNPSPGFAPGHQTAAAGFRLSHLLYSREG 315 >gi|145309320 forkhead box Q1 [Homo sapiens] Length = 403 Score = 81.3 bits (199), Expect = 2e-15 Identities = 56/160 (35%), Positives = 78/160 (48%), Gaps = 10/160 (6%) Query: 77 AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136 A GP G G+ G R R SY LI+ AI + RLTLA+I E+++ P Sbjct: 95 AAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFP 154 Query: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEAT---GKSSWWMLNPEGGKS-GKAPR 192 +F+ S GW+NS+RHNLSL+ F+KV + + GK ++WMLNP + Sbjct: 155 FFR-----GSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVF 209 Query: 193 RRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEG-ATPTSP 231 RR S + P++ P + APP A P SP Sbjct: 210 RRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASP 249 >gi|8923842 forkhead box J2 [Homo sapiens] Length = 574 Score = 81.3 bits (199), Expect = 2e-15 Identities = 60/182 (32%), Positives = 89/182 (48%), Gaps = 22/182 (12%) Query: 76 PAGGPQPGILGAVTGPRKGGSRRNAWGNQ------SYAELISQAIESAPEKRLTLAQIYE 129 P G + G+ T P S+ A +Q SYA LI+ AI S+P K++TL++IY Sbjct: 35 PPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYR 94 Query: 130 WMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLN--PEGG 185 W+ PY+K N+ GWKNSIRHNLSL+ F KV + GK S+W ++ P+ Sbjct: 95 WICDNFPYYK-----NAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPDIS 149 Query: 186 KSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEG------ATPTSPVGHFAKWS 239 + + P S DS + + PPEG +PTS + +++ + Sbjct: 150 RKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTS-IASYSQGT 208 Query: 240 GS 241 GS Sbjct: 209 GS 210 >gi|119395716 forkhead box C1 [Homo sapiens] Length = 553 Score = 79.7 bits (195), Expect = 6e-15 Identities = 50/138 (36%), Positives = 76/138 (55%), Gaps = 16/138 (11%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY LI+ AI++AP+K++TL IY++++ P+++D + GW+NSIRHNLSL+ F Sbjct: 82 SYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRD-----NKQGWQNSIRHNLSLNECF 136 Query: 165 IKV--HNEATGKSSWWMLNPEG---GKSGKAPRRRA------ASMDSSSKLLRGRSKAPK 213 +KV ++ GK S+W L+P+ ++G RRR A D K + P Sbjct: 137 VKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPP 196 Query: 214 KKPSVLPAPPEGATPTSP 231 PAPPE A +P Sbjct: 197 PGRQPPPAPPEQADGNAP 214 >gi|24497506 forkhead box A3 [Homo sapiens] Length = 350 Score = 79.3 bits (194), Expect = 7e-15 Identities = 65/215 (30%), Positives = 95/215 (44%), Gaps = 22/215 (10%) Query: 28 PRSCTWP---LPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGI 84 P S +P LP + + P PP LG G S G P PG+ Sbjct: 45 PLSSPYPPGGLPASPLPSGPLAPPAPAAPLGPTFPGLGVSG-----GSSSSGYGAPGPGL 99 Query: 85 LGAVTGPRKGGSRR---NAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDK 141 + P+ G RR +A SY LI+ AI+ AP K LTL++IY+W++ PY+++ Sbjct: 100 VHGKEMPK--GYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE- 156 Query: 142 GDSNSSAGWKNSIRHNLSLHSKFIKVHN--EATGKSSWWMLNPEGGK--SGKAPRRRAAS 197 + W+NSIRH+LS + F+KV + GK S+W L+P G RR Sbjct: 157 ----NQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKR 212 Query: 198 MDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPV 232 K+ +G S A + + TP + V Sbjct: 213 FKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATV 247 >gi|21618325 forkhead box E1 [Homo sapiens] Length = 373 Score = 79.0 bits (193), Expect = 1e-14 Identities = 52/146 (35%), Positives = 73/146 (50%), Gaps = 23/146 (15%) Query: 83 GILGAVTGPRKGGSRRNAWGNQ-----SYAELISQAIESAPEKRLTLAQIYEWMVRTVPY 137 G+ G TG GG RR + SY LI+ AI APE+RLTL IY+++ P+ Sbjct: 30 GVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPF 89 Query: 138 FKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEA--TGKSSWWMLNPEGGKSGKAPRRRA 195 ++D + W+NSIRHNL+L+ F+K+ EA GK ++W L+P A Sbjct: 90 YRD-----NPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDP-----------NA 133 Query: 196 ASMDSSSKLLRGRSKAPKKKPSVLPA 221 M S LR R + + S PA Sbjct: 134 EDMFESGSFLRRRKRFKRSDLSTYPA 159 >gi|4758392 forkhead box D1 [Homo sapiens] Length = 465 Score = 78.6 bits (192), Expect = 1e-14 Identities = 59/165 (35%), Positives = 82/165 (49%), Gaps = 28/165 (16%) Query: 74 PEPAGGPQPGILGAVTGPRKGGSRRNAWGNQ------SYAELISQAIESAPEKRLTLAQI 127 P PA G G G G GGS + N SY LI+ AI +P+KRLTL++I Sbjct: 92 PAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEI 151 Query: 128 YEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEA--TGKSSWWMLNPEGG 185 E++ PY+++K W+NSIRHNLSL+ F+K+ E GK ++W L+PE Sbjct: 152 CEFISGRFPYYREK-----FPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPE-- 204 Query: 186 KSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTS 230 +A M + LR R K K++P + PP A S Sbjct: 205 ---------SADMFDNGSFLR-RRKRFKRQPLL---PPNAAAAES 236 >gi|28973785 forkhead box S1 [Homo sapiens] Length = 330 Score = 77.4 bits (189), Expect = 3e-14 Identities = 89/334 (26%), Positives = 134/334 (40%), Gaps = 45/334 (13%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY LI+ AI+S+P +R TL+ IY +++ +++ ++ GW+NSIRHNLSL+ F Sbjct: 22 SYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYR-----HNRPGWQNSIRHNLSLNECF 76 Query: 165 IKV--HNEATGKSSWWMLNPE----GGKSGKAPRRRAASMDSSSKLLRGRSKA---PKKK 215 +KV + GK S+W L+P+ RRR + + ++ RG +KA P + Sbjct: 77 VKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRA 136 Query: 216 PSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEAD-MWTTFRPRSSSNASSVSTRLSPL 274 S P P T G CS E D +F + +S+ + Sbjct: 137 TSQDPGVPNATT------------GRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDG 184 Query: 275 RPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGV 334 RP + +EI + G +P TSS S + +GFS Sbjct: 185 RPRPPMEPKEISTPKPACPGELPVA-------------TSSSSCPAFGFPAGFSEAESFN 231 Query: 335 TGPLHTYS--SSLFSPAEGPLSAGEGCFSSSQALEALLTSDTP---PPPADVLMTQVDPI 389 P S S + S + L A C + LE LL S P PP + P+ Sbjct: 232 KAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPL 291 Query: 390 LSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPG 423 + + GG P +GL P PG Sbjct: 292 PTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPG 325 >gi|31563338 forkhead box K2 [Homo sapiens] Length = 660 Score = 76.3 bits (186), Expect = 6e-14 Identities = 91/309 (29%), Positives = 131/309 (42%), Gaps = 59/309 (19%) Query: 34 PLPRP----EIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGILGAVT 89 PLP P AN P G KV GR ++PS L A QP + Sbjct: 196 PLPSPTGTISAANSCPSSPRGAGSSGYKV---GR----VMPSDLNLMADNSQPENEKEAS 248 Query: 90 GPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAG 149 G + ++ SYA+LI QAI AP+K+LTL IY + + PY++ + G Sbjct: 249 GG--DSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYR-----TADKG 301 Query: 150 WKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKS-------------------- 187 W+NSIRHNLSL+ FIKV E GK S+W ++P Sbjct: 302 WQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTP 361 Query: 188 -GKAPRRRAASMDSSSKLLRGRSKAPKKKPSV----LPAP----PEGATPTSPVGHFAKW 238 G R A + + + +L S + S+ PAP P A P V A++ Sbjct: 362 LGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARF 421 Query: 239 S----GSPCSRN----REEADMWTTFRPRSSSNASSVSTRLS-PLRPESEVLAEEIPA-S 288 + GSP S + + +P + + A+ V+T S P ++ + +IPA S Sbjct: 422 AQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVS 481 Query: 289 VSSYAGGVP 297 V+S AG P Sbjct: 482 VTSVAGLAP 490 >gi|22779860 forkhead box L1 [Homo sapiens] Length = 345 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/126 (37%), Positives = 66/126 (52%), Gaps = 23/126 (18%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY LI+ AI+ APE+R+TL IY++++ P++ D + GW+NSIRHNLSL+ F Sbjct: 53 SYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHD-----NRQGWQNSIRHNLSLNDCF 107 Query: 165 IKVHNE--ATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAP 222 +KV E GK S+W L+P R M + G + K+KP P Sbjct: 108 VKVPREKGRPGKGSYWTLDP-----------RCLDMFEN-----GNYRRRKRKPKPGPGA 151 Query: 223 PEGATP 228 PE P Sbjct: 152 PEAKRP 157 >gi|4557595 forkhead box F2 [Homo sapiens] Length = 444 Score = 74.7 bits (182), Expect = 2e-13 Identities = 48/131 (36%), Positives = 66/131 (50%), Gaps = 13/131 (9%) Query: 70 PSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYE 129 PS + AGG G G RR SY LI AI+S+P KRLTL++IY+ Sbjct: 69 PSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQ 128 Query: 130 WMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHN--EATGKSSWWMLNP----- 182 ++ P+F+ + GWKNS+RHNLSL+ FIK+ GK +W ++P Sbjct: 129 FLQARFPFFR-----GAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFM 183 Query: 183 -EGGKSGKAPR 192 E G + PR Sbjct: 184 FEEGSFRRRPR 194 >gi|105554437 forkhead box B1 [Homo sapiens] Length = 325 Score = 74.7 bits (182), Expect = 2e-13 Identities = 93/366 (25%), Positives = 153/366 (41%), Gaps = 66/366 (18%) Query: 91 PRKGGSRRNAWGNQ----SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNS 146 PR G RN + +Q SY L + AI+S+PEK L L++IY++++ PY+++ + Sbjct: 2 PRPG---RNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRE-----N 53 Query: 147 SAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKL 204 + W+NS+RHNLS + FIK+ + GK S+W L+P G M + Sbjct: 54 TQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCG-----------DMFENGSF 102 Query: 205 LRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNA 264 LR R + K L AP + A + AK S + + T P+ + A Sbjct: 103 LRRRKRFKVLKSDHL-APSKPADAAQYLQQQAKLRLSALAAS-------GTHLPQMPAAA 154 Query: 265 SSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGL 324 ++ P + E I A GG+ + + + +++ L ++ Sbjct: 155 YNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQ--------PVPAAYPLPNQLTT 206 Query: 325 SGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEG------------CFSSSQALEALLTS 372 G SL TG H Y S+ + P+S G C ++ Q L A+ Sbjct: 207 MGSSLG----TGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVP 262 Query: 373 DTPPPPA----DVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEA-PGPSSL 427 P P A L + +LS +P L P+SS+ AT P E P+S Sbjct: 263 IKPTPAAVPALPALPAPIPTLLSNSPPSL----SPTSSQTATSQSSPATPSETLTSPASA 318 Query: 428 VPTLSM 433 + ++++ Sbjct: 319 LHSVAV 324 >gi|24497501 forkhead box A1 [Homo sapiens] Length = 472 Score = 73.6 bits (179), Expect = 4e-13 Identities = 35/83 (42%), Positives = 53/83 (63%), Gaps = 7/83 (8%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 SY LI+ AI+ AP K LTL++IY+W++ PY++ + W+NSIRH+LS + F Sbjct: 174 SYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYR-----QNQQRWQNSIRHSLSFNDCF 228 Query: 165 IKVHN--EATGKSSWWMLNPEGG 185 +KV + GK S+W L+P+ G Sbjct: 229 VKVARSPDKPGKGSYWTLHPDSG 251 >gi|110735445 forkhead box F1 [Homo sapiens] Length = 379 Score = 73.6 bits (179), Expect = 4e-13 Identities = 49/128 (38%), Positives = 67/128 (52%), Gaps = 18/128 (14%) Query: 78 GGPQPGILGAVTGPRKG-----GSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMV 132 GG + A +GP K G RR SY LI AI+S+P KRLTL++IY+++ Sbjct: 20 GGGGAAMDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQ 79 Query: 133 RTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHN--EATGKSSWWMLNP------EG 184 P+F+ S GWKNS+RHNLSL+ FIK+ GK +W ++P E Sbjct: 80 SRFPFFR-----GSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 134 Query: 185 GKSGKAPR 192 G + PR Sbjct: 135 GSFRRRPR 142 >gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens] Length = 490 Score = 73.6 bits (179), Expect = 4e-13 Identities = 38/82 (46%), Positives = 51/82 (62%), Gaps = 8/82 (9%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 S++ LI AIE +P KRL + IY W++ PYF +N+ GWKNS+RHNLSL+ F Sbjct: 118 SFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYF-----ANAPTGWKNSVRHNLSLNKCF 172 Query: 165 IKVHNE---ATGKSSWWMLNPE 183 KV E + GK S W ++PE Sbjct: 173 KKVDKERSQSIGKGSLWCIDPE 194 >gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens] Length = 468 Score = 73.6 bits (179), Expect = 4e-13 Identities = 38/82 (46%), Positives = 51/82 (62%), Gaps = 8/82 (9%) Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164 S++ LI AIE +P KRL + IY W++ PYF +N+ GWKNS+RHNLSL+ F Sbjct: 118 SFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYF-----ANAPTGWKNSVRHNLSLNKCF 172 Query: 165 IKVHNE---ATGKSSWWMLNPE 183 KV E + GK S W ++PE Sbjct: 173 KKVDKERSQSIGKGSLWCIDPE 194 >gi|6912372 forkhead box D3 [Homo sapiens] Length = 478 Score = 73.2 bits (178), Expect = 5e-13 Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 44/181 (24%) Query: 42 NQPSEPPEVEPDLGEKV-----HTEGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGS 96 + P+ PPE+ D ++V H P P LP+ A G G G V P G Sbjct: 45 DSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGC 104 Query: 97 RRNAWGNQ--------------------------------SYAELISQAIESAPEKRLTL 124 + G + SY LI+ AI +P+K+LTL Sbjct: 105 KGGVGGEEGGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTL 164 Query: 125 AQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEA--TGKSSWWMLNP 182 + I E++ PY+++K W+NSIRHNLSL+ F+K+ E GK ++W L+P Sbjct: 165 SGICEFISNRFPYYREK-----FPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDP 219 Query: 183 E 183 + Sbjct: 220 Q 220 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.130 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,429,092 Number of Sequences: 37866 Number of extensions: 1539893 Number of successful extensions: 8779 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 112 Number of HSP's successfully gapped in prelim test: 406 Number of HSP's that attempted gapping in prelim test: 7146 Number of HSP's gapped (non-prelim): 1806 length of query: 505 length of database: 18,247,518 effective HSP length: 107 effective length of query: 398 effective length of database: 14,195,856 effective search space: 5649950688 effective search space used: 5649950688 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.