Guide to the Human Genome
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Search of human proteins with 103472003

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|103472003 forkhead box O4 [Homo sapiens]
         (505 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|103472003 forkhead box O4 [Homo sapiens]                          1025   0.0  
gi|42519916 forkhead box O3A [Homo sapiens]                           352   3e-97
gi|4503739 forkhead box O3A [Homo sapiens]                            352   3e-97
gi|9257222 forkhead box O1 [Homo sapiens]                             338   7e-93
gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]        311   1e-84
gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]     269   4e-72
gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]        190   3e-48
gi|208431824 forkhead box I3 [Homo sapiens]                            95   1e-19
gi|4885237 forkhead box C2 [Homo sapiens]                              90   4e-18
gi|32307177 forkhead box G1 [Homo sapiens]                             87   4e-17
gi|50345831 forkhead box J3 [Homo sapiens]                             86   8e-17
gi|134142824 forkhead box D2 [Homo sapiens]                            85   1e-16
gi|21618327 forkhead box I1 isoform a [Homo sapiens]                   83   7e-16
gi|195947376 forkhead box I2 [Homo sapiens]                            82   9e-16
gi|145309320 forkhead box Q1 [Homo sapiens]                            81   2e-15
gi|8923842 forkhead box J2 [Homo sapiens]                              81   2e-15
gi|119395716 forkhead box C1 [Homo sapiens]                            80   6e-15
gi|24497506 forkhead box A3 [Homo sapiens]                             79   7e-15
gi|21618325 forkhead box E1 [Homo sapiens]                             79   1e-14
gi|4758392 forkhead box D1 [Homo sapiens]                              79   1e-14
gi|28973785 forkhead box S1 [Homo sapiens]                             77   3e-14
gi|31563338 forkhead box K2 [Homo sapiens]                             76   6e-14
gi|22779860 forkhead box L1 [Homo sapiens]                             75   1e-13
gi|4557595 forkhead box F2 [Homo sapiens]                              75   2e-13
gi|105554437 forkhead box B1 [Homo sapiens]                            75   2e-13
gi|24497501 forkhead box A1 [Homo sapiens]                             74   4e-13
gi|110735445 forkhead box F1 [Homo sapiens]                            74   4e-13
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]          74   4e-13
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]           74   4e-13
gi|6912372 forkhead box D3 [Homo sapiens]                              73   5e-13

>gi|103472003 forkhead box O4 [Homo sapiens]
          Length = 505

 Score = 1025 bits (2650), Expect = 0.0
 Identities = 505/505 (100%), Positives = 505/505 (100%)

Query: 1   MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT 60
           MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT
Sbjct: 1   MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHT 60

Query: 61  EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK 120
           EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK
Sbjct: 61  EGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEK 120

Query: 121 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML 180
           RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML
Sbjct: 121 RLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWML 180

Query: 181 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG 240
           NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG
Sbjct: 181 NPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSG 240

Query: 241 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL 300
           SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL
Sbjct: 241 SPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTL 300

Query: 301 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF 360
           NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF
Sbjct: 301 NEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCF 360

Query: 361 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE 420
           SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE
Sbjct: 361 SSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLE 420

Query: 421 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE 480
           APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE
Sbjct: 421 APGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLE 480

Query: 481 CDMDNIISDLMDEGEGLDFNFEPDP 505
           CDMDNIISDLMDEGEGLDFNFEPDP
Sbjct: 481 CDMDNIISDLMDEGEGLDFNFEPDP 505


>gi|42519916 forkhead box O3A [Homo sapiens]
          Length = 673

 Score =  352 bits (904), Expect = 3e-97
 Identities = 243/646 (37%), Positives = 328/646 (50%), Gaps = 177/646 (27%)

Query: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEVEPD------------ 53
           ++LDP+FEPQSRPRSCTWPL RPE+   P++P          PE E D            
Sbjct: 16  VELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGS 75

Query: 54  ------------LGEKVHTE-------------------------GRSEPILLPSRLPEP 76
                       LG  +  E                         G ++ +L P    +P
Sbjct: 76  AMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQ---QP 132

Query: 77  AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136
              PQPG  G    PRK  SRRNAWGN SYA+LI++AIES+P+KRLTL+QIYEWMVR VP
Sbjct: 133 LPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVP 192

Query: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAA 196
           YFKDKGDSNSSAGWKNSIRHNLSLHS+F++V NE TGKSSWW++NP+GGKSGKAPRRRA 
Sbjct: 193 YFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAV 252

Query: 197 SMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTF 256
           SMD+S+K  + R +A KKK ++  AP   +   SP    +KW GSP SR+ +E D WT F
Sbjct: 253 SMDNSNKYTKSRGRAAKKKAALQTAPE--SADDSP-SQLSKWPGSPTSRSSDELDAWTDF 309

Query: 257 RPRSSSNASSVSTRLSPLRPES---EVLAEEIPASVSSYAGGV--------PPT------ 299
           R R++SNAS+VS RLSP+   +   EV  ++ P S   Y+           P T      
Sbjct: 310 RSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRL 369

Query: 300 --------LNEGL------ELLDGLNLTSSH-----SLLSRSGLSGFSLQHPGVTGPLHT 340
                   LN+GL      +LLD + L  S       L+ RS    ++ +  G+  P  +
Sbjct: 370 TDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSS 429

Query: 341 YSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLTSDTPPPPADVLMTQ 385
           ++S++F P+      + P+   +      FSS     +Q L+ LLTSD+    +DV+MTQ
Sbjct: 430 FNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDS-LSHSDVMMTQ 488

Query: 386 VDPILSQAPTLL------------------------------------------LLGGLP 403
            DP++SQA T +                                           LGG  
Sbjct: 489 SDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSR 548

Query: 404 SSSKLATGVGL-------CPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTP 456
           + S   + +GL         K  +    S  + TLS      +  S+    +   PV+  
Sbjct: 549 ALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLS----DSLSGSSLYSTSANLPVM-- 602

Query: 457 PTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFE 502
                  ++ P DLDLDM+  +LECDM++II   + + +GLDFNF+
Sbjct: 603 -----GHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFD 643


>gi|4503739 forkhead box O3A [Homo sapiens]
          Length = 673

 Score =  352 bits (904), Expect = 3e-97
 Identities = 243/646 (37%), Positives = 328/646 (50%), Gaps = 177/646 (27%)

Query: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEVEPD------------ 53
           ++LDP+FEPQSRPRSCTWPL RPE+   P++P          PE E D            
Sbjct: 16  VELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGS 75

Query: 54  ------------LGEKVHTE-------------------------GRSEPILLPSRLPEP 76
                       LG  +  E                         G ++ +L P    +P
Sbjct: 76  AMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQ---QP 132

Query: 77  AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136
              PQPG  G    PRK  SRRNAWGN SYA+LI++AIES+P+KRLTL+QIYEWMVR VP
Sbjct: 133 LPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVP 192

Query: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAA 196
           YFKDKGDSNSSAGWKNSIRHNLSLHS+F++V NE TGKSSWW++NP+GGKSGKAPRRRA 
Sbjct: 193 YFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAV 252

Query: 197 SMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTF 256
           SMD+S+K  + R +A KKK ++  AP   +   SP    +KW GSP SR+ +E D WT F
Sbjct: 253 SMDNSNKYTKSRGRAAKKKAALQTAPE--SADDSP-SQLSKWPGSPTSRSSDELDAWTDF 309

Query: 257 RPRSSSNASSVSTRLSPLRPES---EVLAEEIPASVSSYAGGV--------PPT------ 299
           R R++SNAS+VS RLSP+   +   EV  ++ P S   Y+           P T      
Sbjct: 310 RSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRL 369

Query: 300 --------LNEGL------ELLDGLNLTSSH-----SLLSRSGLSGFSLQHPGVTGPLHT 340
                   LN+GL      +LLD + L  S       L+ RS    ++ +  G+  P  +
Sbjct: 370 TDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSS 429

Query: 341 YSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLTSDTPPPPADVLMTQ 385
           ++S++F P+      + P+   +      FSS     +Q L+ LLTSD+    +DV+MTQ
Sbjct: 430 FNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDS-LSHSDVMMTQ 488

Query: 386 VDPILSQAPTLL------------------------------------------LLGGLP 403
            DP++SQA T +                                           LGG  
Sbjct: 489 SDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSR 548

Query: 404 SSSKLATGVGL-------CPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTP 456
           + S   + +GL         K  +    S  + TLS      +  S+    +   PV+  
Sbjct: 549 ALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLS----DSLSGSSLYSTSANLPVM-- 602

Query: 457 PTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFE 502
                  ++ P DLDLDM+  +LECDM++II   + + +GLDFNF+
Sbjct: 603 -----GHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFD 643


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score =  338 bits (867), Expect = 7e-93
 Identities = 254/638 (39%), Positives = 327/638 (51%), Gaps = 153/638 (23%)

Query: 11  EAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQ--------PSEPPEVEPDL-------- 54
           EA  ++++DPDFEP  RPRSCTWPLPRPE +          PS      PD         
Sbjct: 3   EAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSAS 62

Query: 55  GEKVHTEGRSEPILLPSR--LPEPAG-----------------------GPQPGIL---- 85
              V  +  S   LL      P+  G                       GP+ G L    
Sbjct: 63  AAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAP 122

Query: 86  ----------------GAVTGPRKG------GSRRNAWGNQSYAELISQAIESAPEKRLT 123
                            A  GP  G       SRRNAWGN SYA+LI++AIES+ EKRLT
Sbjct: 123 PQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLT 182

Query: 124 LAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPE 183
           L+QIYEWMV++VPYFKDKGDSNSSAGWKNSIRHNLSLHSKFI+V NE TGKSSWWMLNPE
Sbjct: 183 LSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPE 242

Query: 184 GGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPC 243
           GGKSGK+PRRRAASMD++SK  + RS+A KKK S L +  EGA   SP   F+KW  SP 
Sbjct: 243 GGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKAS-LQSGQEGA-GDSPGSQFSKWPASPG 300

Query: 244 SRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAE------EIPASVSSYAGGVP 297
           S + ++ D W+TFRPR+SSNAS++S RLSP+  E + L E        P S +  A  +P
Sbjct: 301 SHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLP 360

Query: 298 PTLN----EGLE-LLDGLNLTSSHSLLSRSGLS-----------------GFSLQHPGVT 335
                   E +E LLD LNL SS + L+ S  S                   SL  P   
Sbjct: 361 SLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPN 420

Query: 336 GPLHTYSSSLFSP-AEGPLSAGEGCFSS----SQ------ALEALLTSDTPPPPADVLMT 384
              +TY  S  SP  + P+   +   SS    SQ       L+ LLTSD+  PP + +MT
Sbjct: 421 YQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDS--PPHNDIMT 478

Query: 385 QVDPILSQAPTLLLLGGL----PSS------SKLATGVGLCPKPLEAPGPSSLVPTLSMI 434
            VDP ++Q P   +LG      P+S      S+ +    + P     PG +     ++  
Sbjct: 479 PVDPGVAQ-PNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGR 537

Query: 435 APPPVMASAPIPKALG------TPVLTP---PTEAAS--------------------QDR 465
             P  +++ P    +       TPV  P   P + ++                    Q++
Sbjct: 538 PLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEK 597

Query: 466 MPQDLDLDMYMENLECDMDNII-SDLMDEGEGLDFNFE 502
           +P DLD  M++E L+CDM++II +DLMD G+ LDFNF+
Sbjct: 598 LPSDLD-GMFIERLDCDMESIIRNDLMD-GDTLDFNFD 633


>gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 492

 Score =  311 bits (796), Expect = 1e-84
 Identities = 209/504 (41%), Positives = 263/504 (52%), Gaps = 61/504 (12%)

Query: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75
           +D+DPDF PQSRPRSCTWPLP+P++A    E   +   + E     G       P+  P 
Sbjct: 10  VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67

Query: 76  PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133
           P        LGA  GP  +   SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR
Sbjct: 68  PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120

Query: 134 TVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRR 193
            VPYFKDKGDSNSSAGWKNSIRHNLSLH++FI+V NE TGKSSWWMLNPEGGK+GK PRR
Sbjct: 121 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 180

Query: 194 RAASMDSSSKLLRGRSKAPKKKPSVLP-APPEGATPTS----PVGHFAKWSGSPCSRNRE 248
           RA SMD+ +K LR + KA KKK    P   P+ ++P++    PV   AKW+ SP S   +
Sbjct: 181 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 240

Query: 249 EADMWTTFRPRSSSNASSVSTRLSPLRPES--EVLAEEIPASVSSYAGGVPPTLNEGL-- 304
           + + W  FR         +    + L  +   E LA   P    S A  + P L      
Sbjct: 241 DYEAWADFR----GGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPG 296

Query: 305 ELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCFSSSQ 364
           EL     L      L   G  G  L    + G    Y     +P  GP+    G  + + 
Sbjct: 297 EL---PRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRP-APRPGPVLGAPGELALAG 352

Query: 365 ALEALLTSDTPP--PPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAP 422
           A  A       P  PPA                       PS S LA  + L   P EA 
Sbjct: 353 AAAAYPGKGAAPYAPPA-----------------------PSRSALAHPISLMTLPGEA- 388

Query: 423 GPSSLVP---TLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENL 479
           G + L P     +   PP  +    +P         P    A+ DR P DLDLDM+  +L
Sbjct: 389 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGP--LGAAPDRFPADLDLDMFSGSL 446

Query: 480 ECDMDNII-SDLMDEGEGLDFNFE 502
           ECD+++II +D MD  E +DFNF+
Sbjct: 447 ECDVESIILNDFMDSDE-MDFNFD 469


>gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]
          Length = 562

 Score =  269 bits (688), Expect = 4e-72
 Identities = 139/249 (55%), Positives = 170/249 (68%), Gaps = 16/249 (6%)

Query: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75
           +D+DPDF PQSRP S TWPLP+P++A    E   +   + E     G       P+  P 
Sbjct: 187 VDVDPDFAPQSRPHSSTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 244

Query: 76  PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133
           P        LGA  GP  +   SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR
Sbjct: 245 PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 297

Query: 134 TVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRR 193
            VPYFKDKGDSNSSAGWKNSIRHNLSLH++FI+V NE TGKSSWWMLNPEGGK+GK PRR
Sbjct: 298 YVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRR 357

Query: 194 RAASMDSSSKLLRGRSKAPKKKPSVLP-APPEGATPTS----PVGHFAKWSGSPCSRNRE 248
           RA SMD+ +K LR + KA KKK    P   P+ ++P++    PV   AKW+ SP S   +
Sbjct: 358 RAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASD 417

Query: 249 EADMWTTFR 257
           + + W  FR
Sbjct: 418 DYEAWADFR 426


>gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 589

 Score =  190 bits (482), Expect = 3e-48
 Identities = 185/588 (31%), Positives = 253/588 (43%), Gaps = 132/588 (22%)

Query: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75
           +D+DPDF PQSRPRSCTWPLP+P++A    E   +   + E     G       P+  P 
Sbjct: 10  VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67

Query: 76  PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133
           P        LGA  GP  +   SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR
Sbjct: 68  PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120

Query: 134 TVPYFKDKGDSNSSAGWKNSI---------RHNLSLHSKFIKVHNEATGKSSWWMLNPEG 184
            VPYFKDKGDSNSSAGWK            R  L   ++ + +     G+     L P G
Sbjct: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQE---GRQKEGFLAPPG 177

Query: 185 ---GKSGKAPRRRAASMDSSSKLLRGRSKAPKKK-------PSV-------LPAPPEGAT 227
                S +AP        SSS +LRG S AP+         P V       L   P+   
Sbjct: 178 VTESCSSRAP--------SSSFVLRG-SPAPRADGGGEVTFPEVATCEVVDLGIGPQARA 228

Query: 228 PTSPVGHFAKWSGSPCSRNRE--EADMWTTFRPRSSSNASSVSTRLSP--------LRPE 277
            + P+G   +  G+    + E      W  F P S+++ S+    ++         +  +
Sbjct: 229 FSVPLGASLQGWGTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQ 288

Query: 278 SEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLS----------------- 320
            E   E +  +    A G+P  LN+GL+         S  L S                 
Sbjct: 289 EEAWTENLNFTPDGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESD 348

Query: 321 ----------------RSGLSGFSLQHPGVTGPLHT--------YSSSLFSPAEGPLSAG 356
                           R+GL+       G TG  H+          + +F    G  +  
Sbjct: 349 QCLELGQYLDQEVEATRTGLAKAG-SDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATH 407

Query: 357 EGCFSSSQALEALLTSDT--PPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGL 414
            G F  +     L       PPPPA     +  P+L  AP  L L G   ++    G G 
Sbjct: 408 CGDFEKAPTARGLEGRQVVPPPPPA----PRPGPVLG-APGELALAG---AAAAYPGKGA 459

Query: 415 CPKPLEAPGPSSLVPTLSMIAPPPVMASAPI------------PKALGTPVLTPPTEA-- 460
            P    AP  S+L   +S++  P    +A +            P  L    L  P  A  
Sbjct: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519

Query: 461 -----ASQDRMPQDLDLDMYMENLECDMDNII-SDLMDEGEGLDFNFE 502
                A+ DR P DLDLDM+  +LECD+++II +D MD  E +DFNF+
Sbjct: 520 AGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDE-MDFNFD 566


>gi|208431824 forkhead box I3 [Homo sapiens]
          Length = 420

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 108/362 (29%), Positives = 162/362 (44%), Gaps = 69/362 (19%)

Query: 34  PLPRPEIANQPS-EPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGILGAVTGPR 92
           P P P  A  P  +PP      G       +  P   P+    PAG   PG LG ++   
Sbjct: 81  PPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAA-PASPAAPAG---PGELGWLSMAS 136

Query: 93  KGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKN 152
           +    +      SY+ LI+ AI+SAPE++LTL+ IY+++  + P+++      S AGW+N
Sbjct: 137 REDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQ-----RSKAGWQN 191

Query: 153 SIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGK-----SGKAPRRRAASMDSSSKLL 205
           SIRHNLSL+  F KV    +  GK ++W L+P   K     + +  R+R +   + S + 
Sbjct: 192 SIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASNGSTVA 251

Query: 206 RGRSKAPK----------------------KKPSVLPAPPEG--ATPTSPVGHFAKWSGS 241
            G SK+ +                       +PS  P PPEG  +T +SP G     + +
Sbjct: 252 AGTSKSEEGLSSGLGSGVGGKPEEESPSTLLRPSHSPEPPEGTKSTASSPGGPML--TST 309

Query: 242 PCSRNREEADMWTTFRPRSS-SNASSVST-RLSPLRPESEVLAEEIPASVSSYAGGV--P 297
           PC        + T F   SS S +SSVST R  P      +   ++P+S      GV  P
Sbjct: 310 PC--------LNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSS------GVFSP 355

Query: 298 PTLNE-GLELLDGLNLTSSHSLLSRSGLSGFSLQHPG-----VTGPLHTYS--SSLFSPA 349
            +++E   + L   N TS+ +    S  S F     G      + P H +S  +SL  P 
Sbjct: 356 TSISEASADTLQLSNSTSNSTGQRSSYYSPFPASTSGGQSSPFSSPFHNFSMVNSLIYPR 415

Query: 350 EG 351
           EG
Sbjct: 416 EG 417


>gi|4885237 forkhead box C2 [Homo sapiens]
          Length = 501

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 80/264 (30%), Positives = 125/264 (47%), Gaps = 57/264 (21%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY  LI+ AI++APEK++TL  IY++++   P++++     +  GW+NSIRHNLSL+  F
Sbjct: 76  SYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRE-----NKQGWQNSIRHNLSLNECF 130

Query: 165 IKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSV---- 218
           +KV   ++  GK S+W L+P+           + +M  +   LR R +  KK  S     
Sbjct: 131 VKVPRDDKKPGKGSYWTLDPD-----------SYNMFENGSFLRRRRRFKKKDVSKEKEE 179

Query: 219 ---LPAPPEGATPTSP-VGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPL 274
              L  PP  A+  +P   H A    +P     +EA+     +  ++S A  V T++  L
Sbjct: 180 RAHLKEPPPAASKGAPATPHLA---DAP-----KEAEKKVVIKSEAASPALPVITKVETL 231

Query: 275 RPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGV 334
            PES +  +  P S +S   G P          DG      H   + +GL GFS+++   
Sbjct: 232 SPESAL--QGSPRSAASTPAGSP----------DG--SLPEHHAAAPNGLPGFSVEN--- 274

Query: 335 TGPLHTYSSSLFSPAEGPLSAGEG 358
                   +   SP  G LS G G
Sbjct: 275 ------IMTLRTSPPGGELSPGAG 292


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 71/227 (31%), Positives = 94/227 (41%), Gaps = 70/227 (30%)

Query: 34  PLPRPEIANQPSEPPEVEPDLGEKVHTEGRS--------EPILLPSRLP----------- 74
           P P+P    Q  +PP   P   +   T G          + +LLP   P           
Sbjct: 61  PAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAK 120

Query: 75  --------EPAGGPQPGILGAV------TGPRKGGSRRNAWGNQ---------------- 104
                   EP GGP  G L  V       G   GG  +   G                  
Sbjct: 121 ADGLGGKGEPGGGP--GELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGK 178

Query: 105 ------SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNL 158
                 SY  LI  AI  +PEKRLTL  IYE++++  PY+++     +  GW+NSIRHNL
Sbjct: 179 YEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRE-----NKQGWQNSIRHNL 233

Query: 159 SLHSKFIKV--HNEATGKSSWWMLNPE------GGKSGKAPRRRAAS 197
           SL+  F+KV  H +  GK ++WML+P       GG +GK  RR   S
Sbjct: 234 SLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTS 280


>gi|50345831 forkhead box J3 [Homo sapiens]
          Length = 622

 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 44/102 (43%), Positives = 68/102 (66%), Gaps = 9/102 (8%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SYA LI+ AI S+P+K++TL++IY+W+    PY+++ G     +GWKNSIRHNLSL+  F
Sbjct: 82  SYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAG-----SGWKNSIRHNLSLNKCF 136

Query: 165 IKV--HNEATGKSSWWML--NPEGGKSGKAPRRRAASMDSSS 202
           +KV    +  GK S+W +  NP+       P++RA S++ +S
Sbjct: 137 LKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERAS 178


>gi|134142824 forkhead box D2 [Homo sapiens]
          Length = 495

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 84/265 (31%), Positives = 118/265 (44%), Gaps = 52/265 (19%)

Query: 7   NSATEAAAIIDLDPDFE------------PQSRPRSCTWPLPRPEIANQPSEPP--EVEP 52
           +S +  AA+ + D D +             +S PR+     PR ++     EPP  E E 
Sbjct: 12  SSESSPAALSEADADIDVVGGGSGGGELPARSGPRA-----PR-DVLPHGHEPPAEEAEA 65

Query: 53  DLGEKVHTEGR---SEPILLPSR-LPEPAGGPQPGIL------GAVTGPRKGGSRRNA-- 100
           DL E     G     EP  L SR     AG P PG        G   GP  GG+   +  
Sbjct: 66  DLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPL 125

Query: 101 -WGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLS 159
                SY  LI+ AI  +P+KRLTL++I E++    PY+++K        W+NSIRHNLS
Sbjct: 126 VKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREK-----FPAWQNSIRHNLS 180

Query: 160 LHSKFIKVHNEA--TGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPS 217
           L+  F+K+  E    GK ++W L+PE           +A M  +   LR R K  K++P 
Sbjct: 181 LNDCFVKIPREPGNPGKGNYWTLDPE-----------SADMFDNGSFLR-RRKRFKRQPL 228

Query: 218 VLPAPPEGATPTSPVGHFAKWSGSP 242
             P P     P   +   A  +G P
Sbjct: 229 PPPHPHPHPHPELLLRGGAAAAGDP 253


>gi|21618327 forkhead box I1 isoform a [Homo sapiens]
          Length = 378

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 58/156 (37%), Positives = 80/156 (51%), Gaps = 22/156 (14%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY+ LI+ AI  AP+KRLTL+QIY+++    P++     + S AGW+NSIRHNLSL+  F
Sbjct: 127 SYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFY-----NKSKAGWQNSIRHNLSLNDCF 181

Query: 165 IKV--HNEATGKSSWWMLNPEGGK---SGKAPRRRAASMDSSSK-----LLRGRSKAPKK 214
            KV    +  GK ++W L+P   K   +G   R+R    D SS      L +  S  P  
Sbjct: 182 KKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVD 241

Query: 215 KP------SVLPAPPEGATPTSPVGH-FAKWSGSPC 243
            P       +L     G T +SP        SG+PC
Sbjct: 242 SPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPC 277


>gi|195947376 forkhead box I2 [Homo sapiens]
          Length = 318

 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 72/230 (31%), Positives = 108/230 (46%), Gaps = 31/230 (13%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY+ LI+ AI+SAP ++LTL+QIY+++    P++K      S AGW+NSIRHNLSL+  F
Sbjct: 106 SYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYK-----RSKAGWQNSIRHNLSLNDCF 160

Query: 165 IKV--HNEATGKSSWWMLNPEGGK---SGKAPRRRAASMDSSSKLLRG-RSKAPKKKPSV 218
            KV    +  GK ++W L+P   K   +G   R+R    ++S+ +  G RS    + P++
Sbjct: 161 KKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPAL 220

Query: 219 LPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPES 278
            P          P         SP     E A  ++ F    S+ A  + T   P     
Sbjct: 221 EP----------PSAACLDLQASPSPSAPEAATCFSGFASAMSALAGGLGT--FPGGLAG 268

Query: 279 EVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTS-----SHSLLSRSG 323
           +      P +V+++A   P TLN       G    +     SH L SR G
Sbjct: 269 DFSFGRRPPTVATHA---PQTLNPSPGFAPGHQTAAAGFRLSHLLYSREG 315


>gi|145309320 forkhead box Q1 [Homo sapiens]
          Length = 403

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 56/160 (35%), Positives = 78/160 (48%), Gaps = 10/160 (6%)

Query: 77  AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136
           A GP  G  G+  G R     R      SY  LI+ AI  +   RLTLA+I E+++   P
Sbjct: 95  AAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFP 154

Query: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEAT---GKSSWWMLNPEGGKS-GKAPR 192
           +F+      S  GW+NS+RHNLSL+  F+KV  + +   GK ++WMLNP    +      
Sbjct: 155 FFR-----GSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVF 209

Query: 193 RRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEG-ATPTSP 231
           RR     S    +      P++ P +  APP   A P SP
Sbjct: 210 RRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASP 249


>gi|8923842 forkhead box J2 [Homo sapiens]
          Length = 574

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 60/182 (32%), Positives = 89/182 (48%), Gaps = 22/182 (12%)

Query: 76  PAGGPQPGILGAVTGPRKGGSRRNAWGNQ------SYAELISQAIESAPEKRLTLAQIYE 129
           P G  +    G+ T P    S+  A  +Q      SYA LI+ AI S+P K++TL++IY 
Sbjct: 35  PPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYR 94

Query: 130 WMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLN--PEGG 185
           W+    PY+K     N+  GWKNSIRHNLSL+  F KV    +  GK S+W ++  P+  
Sbjct: 95  WICDNFPYYK-----NAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPDIS 149

Query: 186 KSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEG------ATPTSPVGHFAKWS 239
           +  + P     S DS  +      +           PPEG       +PTS +  +++ +
Sbjct: 150 RKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTS-IASYSQGT 208

Query: 240 GS 241
           GS
Sbjct: 209 GS 210


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 50/138 (36%), Positives = 76/138 (55%), Gaps = 16/138 (11%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY  LI+ AI++AP+K++TL  IY++++   P+++D     +  GW+NSIRHNLSL+  F
Sbjct: 82  SYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRD-----NKQGWQNSIRHNLSLNECF 136

Query: 165 IKV--HNEATGKSSWWMLNPEG---GKSGKAPRRRA------ASMDSSSKLLRGRSKAPK 213
           +KV   ++  GK S+W L+P+     ++G   RRR       A  D   K      + P 
Sbjct: 137 VKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPP 196

Query: 214 KKPSVLPAPPEGATPTSP 231
                 PAPPE A   +P
Sbjct: 197 PGRQPPPAPPEQADGNAP 214


>gi|24497506 forkhead box A3 [Homo sapiens]
          Length = 350

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 65/215 (30%), Positives = 95/215 (44%), Gaps = 22/215 (10%)

Query: 28  PRSCTWP---LPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGI 84
           P S  +P   LP   + + P  PP     LG      G S             G P PG+
Sbjct: 45  PLSSPYPPGGLPASPLPSGPLAPPAPAAPLGPTFPGLGVSG-----GSSSSGYGAPGPGL 99

Query: 85  LGAVTGPRKGGSRR---NAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDK 141
           +     P+  G RR   +A    SY  LI+ AI+ AP K LTL++IY+W++   PY+++ 
Sbjct: 100 VHGKEMPK--GYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE- 156

Query: 142 GDSNSSAGWKNSIRHNLSLHSKFIKVHN--EATGKSSWWMLNPEGGK--SGKAPRRRAAS 197
               +   W+NSIRH+LS +  F+KV    +  GK S+W L+P  G         RR   
Sbjct: 157 ----NQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKR 212

Query: 198 MDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPV 232
                K+ +G S A     +   +     TP + V
Sbjct: 213 FKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATV 247


>gi|21618325 forkhead box E1 [Homo sapiens]
          Length = 373

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 52/146 (35%), Positives = 73/146 (50%), Gaps = 23/146 (15%)

Query: 83  GILGAVTGPRKGGSRRNAWGNQ-----SYAELISQAIESAPEKRLTLAQIYEWMVRTVPY 137
           G+ G  TG   GG RR     +     SY  LI+ AI  APE+RLTL  IY+++    P+
Sbjct: 30  GVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPF 89

Query: 138 FKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEA--TGKSSWWMLNPEGGKSGKAPRRRA 195
           ++D     +   W+NSIRHNL+L+  F+K+  EA   GK ++W L+P            A
Sbjct: 90  YRD-----NPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDP-----------NA 133

Query: 196 ASMDSSSKLLRGRSKAPKKKPSVLPA 221
             M  S   LR R +  +   S  PA
Sbjct: 134 EDMFESGSFLRRRKRFKRSDLSTYPA 159


>gi|4758392 forkhead box D1 [Homo sapiens]
          Length = 465

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 59/165 (35%), Positives = 82/165 (49%), Gaps = 28/165 (16%)

Query: 74  PEPAGGPQPGILGAVTGPRKGGSRRNAWGNQ------SYAELISQAIESAPEKRLTLAQI 127
           P PA G   G  G   G   GGS  +   N       SY  LI+ AI  +P+KRLTL++I
Sbjct: 92  PAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEI 151

Query: 128 YEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEA--TGKSSWWMLNPEGG 185
            E++    PY+++K        W+NSIRHNLSL+  F+K+  E    GK ++W L+PE  
Sbjct: 152 CEFISGRFPYYREK-----FPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPE-- 204

Query: 186 KSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTS 230
                    +A M  +   LR R K  K++P +   PP  A   S
Sbjct: 205 ---------SADMFDNGSFLR-RRKRFKRQPLL---PPNAAAAES 236


>gi|28973785 forkhead box S1 [Homo sapiens]
          Length = 330

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 89/334 (26%), Positives = 134/334 (40%), Gaps = 45/334 (13%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY  LI+ AI+S+P +R TL+ IY +++    +++     ++  GW+NSIRHNLSL+  F
Sbjct: 22  SYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYR-----HNRPGWQNSIRHNLSLNECF 76

Query: 165 IKV--HNEATGKSSWWMLNPE----GGKSGKAPRRRAASMDSSSKLLRGRSKA---PKKK 215
           +KV   +   GK S+W L+P+            RRR  +  + ++  RG +KA   P + 
Sbjct: 77  VKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRA 136

Query: 216 PSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEAD-MWTTFRPRSSSNASSVSTRLSPL 274
            S  P  P   T            G  CS   E  D    +F     +  +S+    +  
Sbjct: 137 TSQDPGVPNATT------------GRQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDG 184

Query: 275 RPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGV 334
           RP   +  +EI     +  G +P               TSS S  +    +GFS      
Sbjct: 185 RPRPPMEPKEISTPKPACPGELPVA-------------TSSSSCPAFGFPAGFSEAESFN 231

Query: 335 TGPLHTYS--SSLFSPAEGPLSAGEGCFSSSQALEALLTSDTP---PPPADVLMTQVDPI 389
             P    S  S + S  +  L A   C  +   LE LL S  P   PP     +    P+
Sbjct: 232 KAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPTPPGSLRAPLPL 291

Query: 390 LSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPG 423
            +      + GG P        +GL P     PG
Sbjct: 292 PTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPG 325


>gi|31563338 forkhead box K2 [Homo sapiens]
          Length = 660

 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 91/309 (29%), Positives = 131/309 (42%), Gaps = 59/309 (19%)

Query: 34  PLPRP----EIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGILGAVT 89
           PLP P      AN     P      G KV   GR    ++PS L   A   QP      +
Sbjct: 196 PLPSPTGTISAANSCPSSPRGAGSSGYKV---GR----VMPSDLNLMADNSQPENEKEAS 248

Query: 90  GPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAG 149
           G      + ++    SYA+LI QAI  AP+K+LTL  IY  + +  PY++      +  G
Sbjct: 249 GG--DSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYR-----TADKG 301

Query: 150 WKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKS-------------------- 187
           W+NSIRHNLSL+  FIKV    E  GK S+W ++P                         
Sbjct: 302 WQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTP 361

Query: 188 -GKAPRRRAASMDSSSKLLRGRSKAPKKKPSV----LPAP----PEGATPTSPVGHFAKW 238
            G    R A +  + + +L   S   +   S+     PAP    P  A P   V   A++
Sbjct: 362 LGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARF 421

Query: 239 S----GSPCSRN----REEADMWTTFRPRSSSNASSVSTRLS-PLRPESEVLAEEIPA-S 288
           +    GSP S        +  +    +P + + A+ V+T  S P   ++  +  +IPA S
Sbjct: 422 AQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVS 481

Query: 289 VSSYAGGVP 297
           V+S AG  P
Sbjct: 482 VTSVAGLAP 490


>gi|22779860 forkhead box L1 [Homo sapiens]
          Length = 345

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 47/126 (37%), Positives = 66/126 (52%), Gaps = 23/126 (18%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY  LI+ AI+ APE+R+TL  IY++++   P++ D     +  GW+NSIRHNLSL+  F
Sbjct: 53  SYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHD-----NRQGWQNSIRHNLSLNDCF 107

Query: 165 IKVHNE--ATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAP 222
           +KV  E    GK S+W L+P           R   M  +     G  +  K+KP   P  
Sbjct: 108 VKVPREKGRPGKGSYWTLDP-----------RCLDMFEN-----GNYRRRKRKPKPGPGA 151

Query: 223 PEGATP 228
           PE   P
Sbjct: 152 PEAKRP 157


>gi|4557595 forkhead box F2 [Homo sapiens]
          Length = 444

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 48/131 (36%), Positives = 66/131 (50%), Gaps = 13/131 (9%)

Query: 70  PSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYE 129
           PS   + AGG   G           G RR      SY  LI  AI+S+P KRLTL++IY+
Sbjct: 69  PSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQ 128

Query: 130 WMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHN--EATGKSSWWMLNP----- 182
           ++    P+F+      +  GWKNS+RHNLSL+  FIK+       GK  +W ++P     
Sbjct: 129 FLQARFPFFR-----GAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFM 183

Query: 183 -EGGKSGKAPR 192
            E G   + PR
Sbjct: 184 FEEGSFRRRPR 194


>gi|105554437 forkhead box B1 [Homo sapiens]
          Length = 325

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 93/366 (25%), Positives = 153/366 (41%), Gaps = 66/366 (18%)

Query: 91  PRKGGSRRNAWGNQ----SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNS 146
           PR G   RN + +Q    SY  L + AI+S+PEK L L++IY++++   PY+++     +
Sbjct: 2   PRPG---RNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRE-----N 53

Query: 147 SAGWKNSIRHNLSLHSKFIKV--HNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKL 204
           +  W+NS+RHNLS +  FIK+    +  GK S+W L+P  G            M  +   
Sbjct: 54  TQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCG-----------DMFENGSF 102

Query: 205 LRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNA 264
           LR R +    K   L AP + A     +   AK   S  + +        T  P+  + A
Sbjct: 103 LRRRKRFKVLKSDHL-APSKPADAAQYLQQQAKLRLSALAAS-------GTHLPQMPAAA 154

Query: 265 SSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGL 324
            ++     P   +     E I A      GG+  +  +         + +++ L ++   
Sbjct: 155 YNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQ--------PVPAAYPLPNQLTT 206

Query: 325 SGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEG------------CFSSSQALEALLTS 372
            G SL     TG  H Y S+    +  P+S   G            C ++ Q L A+   
Sbjct: 207 MGSSLG----TGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVP 262

Query: 373 DTPPPPA----DVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEA-PGPSSL 427
             P P A      L   +  +LS +P  L     P+SS+ AT       P E    P+S 
Sbjct: 263 IKPTPAAVPALPALPAPIPTLLSNSPPSL----SPTSSQTATSQSSPATPSETLTSPASA 318

Query: 428 VPTLSM 433
           + ++++
Sbjct: 319 LHSVAV 324


>gi|24497501 forkhead box A1 [Homo sapiens]
          Length = 472

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 35/83 (42%), Positives = 53/83 (63%), Gaps = 7/83 (8%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           SY  LI+ AI+ AP K LTL++IY+W++   PY++      +   W+NSIRH+LS +  F
Sbjct: 174 SYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYR-----QNQQRWQNSIRHSLSFNDCF 228

Query: 165 IKVHN--EATGKSSWWMLNPEGG 185
           +KV    +  GK S+W L+P+ G
Sbjct: 229 VKVARSPDKPGKGSYWTLHPDSG 251


>gi|110735445 forkhead box F1 [Homo sapiens]
          Length = 379

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 49/128 (38%), Positives = 67/128 (52%), Gaps = 18/128 (14%)

Query: 78  GGPQPGILGAVTGPRKG-----GSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMV 132
           GG    +  A +GP K      G RR      SY  LI  AI+S+P KRLTL++IY+++ 
Sbjct: 20  GGGGAAMDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQ 79

Query: 133 RTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHN--EATGKSSWWMLNP------EG 184
              P+F+      S  GWKNS+RHNLSL+  FIK+       GK  +W ++P      E 
Sbjct: 80  SRFPFFR-----GSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 134

Query: 185 GKSGKAPR 192
           G   + PR
Sbjct: 135 GSFRRRPR 142


>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
          Length = 490

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 38/82 (46%), Positives = 51/82 (62%), Gaps = 8/82 (9%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           S++ LI  AIE +P KRL +  IY W++   PYF     +N+  GWKNS+RHNLSL+  F
Sbjct: 118 SFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYF-----ANAPTGWKNSVRHNLSLNKCF 172

Query: 165 IKVHNE---ATGKSSWWMLNPE 183
            KV  E   + GK S W ++PE
Sbjct: 173 KKVDKERSQSIGKGSLWCIDPE 194


>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
          Length = 468

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 38/82 (46%), Positives = 51/82 (62%), Gaps = 8/82 (9%)

Query: 105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKF 164
           S++ LI  AIE +P KRL +  IY W++   PYF     +N+  GWKNS+RHNLSL+  F
Sbjct: 118 SFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYF-----ANAPTGWKNSVRHNLSLNKCF 172

Query: 165 IKVHNE---ATGKSSWWMLNPE 183
            KV  E   + GK S W ++PE
Sbjct: 173 KKVDKERSQSIGKGSLWCIDPE 194


>gi|6912372 forkhead box D3 [Homo sapiens]
          Length = 478

 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 44/181 (24%)

Query: 42  NQPSEPPEVEPDLGEKV-----HTEGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGS 96
           + P+ PPE+  D  ++V     H      P   P  LP+ A G   G  G V  P   G 
Sbjct: 45  DSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGC 104

Query: 97  RRNAWGNQ--------------------------------SYAELISQAIESAPEKRLTL 124
           +    G +                                SY  LI+ AI  +P+K+LTL
Sbjct: 105 KGGVGGEEGGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTL 164

Query: 125 AQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEA--TGKSSWWMLNP 182
           + I E++    PY+++K        W+NSIRHNLSL+  F+K+  E    GK ++W L+P
Sbjct: 165 SGICEFISNRFPYYREK-----FPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDP 219

Query: 183 E 183
           +
Sbjct: 220 Q 220


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.130    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,429,092
Number of Sequences: 37866
Number of extensions: 1539893
Number of successful extensions: 8779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 406
Number of HSP's that attempted gapping in prelim test: 7146
Number of HSP's gapped (non-prelim): 1806
length of query: 505
length of database: 18,247,518
effective HSP length: 107
effective length of query: 398
effective length of database: 14,195,856
effective search space: 5649950688
effective search space used: 5649950688
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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