Search of human proteins with 10092601

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
[Homo sapiens]
         (1585 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...  3155   0.0  
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...  1273   0.0  
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...  1273   0.0  
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...  1259   0.0  
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...  1214   0.0  
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...  1171   0.0  
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2...   190   8e-48
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i...   190   8e-48
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             71   7e-12
gi|34452730 poly(A) binding protein interacting protein 1 isofor...    68   8e-11
gi|33386693 poly(A) binding protein interacting protein 1 isofor...    68   8e-11
gi|17511255 poly(A) binding protein interacting protein 1 isofor...    68   8e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    67   1e-10
gi|116284392 mucin 2 precursor [Homo sapiens]                          66   3e-10
gi|169212085 PREDICTED: similar to poly(A) binding protein inter...    65   7e-10
gi|239752553 PREDICTED: similar to poly(A) binding protein inter...    65   7e-10
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              65   7e-10
gi|89041275 PREDICTED: similar to poly(A) binding protein intera...    65   7e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   64   1e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   64   1e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   64   1e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    64   1e-09
gi|110349719 titin isoform N2-A [Homo sapiens]                         63   2e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni...    62   3e-09
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         62   6e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    61   1e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    60   2e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is...    59   5e-08
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         58   6e-08
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        57   1e-07

>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
            sapiens]
          Length = 1585

 Score = 3155 bits (8181), Expect = 0.0
 Identities = 1585/1585 (100%), Positives = 1585/1585 (100%)

Query: 1    MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV 60
            MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV
Sbjct: 1    MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV 60

Query: 61   PQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQ 120
            PQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQ
Sbjct: 61   PQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQ 120

Query: 121  SAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP 180
            SAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP
Sbjct: 121  SAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP 180

Query: 181  PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS 240
            PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS
Sbjct: 181  PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS 240

Query: 241  GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR 300
            GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR
Sbjct: 241  GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR 300

Query: 301  CELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEIN 360
            CELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEIN
Sbjct: 301  CELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEIN 360

Query: 361  GVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT 420
            GVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT
Sbjct: 361  GVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT 420

Query: 421  PPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQ 480
            PPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQ
Sbjct: 421  PPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQ 480

Query: 481  TEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKV 540
            TEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKV
Sbjct: 481  TEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKV 540

Query: 541  LESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSS 600
            LESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSS
Sbjct: 541  LESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSS 600

Query: 601  GDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPK 660
            GDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPK
Sbjct: 601  GDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPK 660

Query: 661  LPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSV 720
            LPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSV
Sbjct: 661  LPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSV 720

Query: 721  KEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGL 780
            KEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGL
Sbjct: 721  KEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGL 780

Query: 781  TVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNR 840
            TVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNR
Sbjct: 781  TVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNR 840

Query: 841  CQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF 900
            CQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF
Sbjct: 841  CQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF 900

Query: 901  KLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIV 960
            KLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIV
Sbjct: 901  KLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIV 960

Query: 961  KERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK 1020
            KERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK
Sbjct: 961  KERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK 1020

Query: 1021 EKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSS 1080
            EKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSS
Sbjct: 1021 EKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSS 1080

Query: 1081 GGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKP 1140
            GGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKP
Sbjct: 1081 GGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKP 1140

Query: 1141 LPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRE 1200
            LPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRE
Sbjct: 1141 LPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRE 1200

Query: 1201 SAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVR 1260
            SAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVR
Sbjct: 1201 SAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVR 1260

Query: 1261 VGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYL 1320
            VGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYL
Sbjct: 1261 VGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYL 1320

Query: 1321 AELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREAD 1380
            AELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREAD
Sbjct: 1321 AELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREAD 1380

Query: 1381 LSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAN 1440
            LSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAN
Sbjct: 1381 LSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAN 1440

Query: 1441 DEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYL 1500
            DEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYL
Sbjct: 1441 DEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYL 1500

Query: 1501 DSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNG 1560
            DSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNG
Sbjct: 1501 DSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNG 1560

Query: 1561 KGVALKSVTAFFTWLREAEEESEDN 1585
            KGVALKSVTAFFTWLREAEEESEDN
Sbjct: 1561 KGVALKSVTAFFTWLREAEEESEDN 1585


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 1273 bits (3294), Expect = 0.0
 Identities = 808/1669 (48%), Positives = 1006/1669 (60%), Gaps = 194/1669 (11%)

Query: 1    MNSQPQTRSPFFQRPQIQPPR--ATIPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMP 57
            MN+  Q R  F+   + QPP   A+   S+   RPG   P A VY A   +MM+    + 
Sbjct: 41   MNTPSQPRQHFYPS-RAQPPSSAASRVQSAAPARPG---PAAHVYPAGSQVMMIPS-QIS 95

Query: 58   YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP 117
            YP  QG  Y   Q R +   YV P QQYPVQP  PG FYPG  P +F   Y   +YP+Q 
Sbjct: 96   YPASQGAYYIPGQGRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQG 150

Query: 118  VYQSAPIIVPT---QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172
            V Q    + P      QPP    KRE+KTIRIRDPNQGGKDITEEIMSG           
Sbjct: 151  VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA---------- 200

Query: 173  RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223
            R  STPTPPQ    L  Q    +P V   V      + A +A    +        E +P 
Sbjct: 201  RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 260

Query: 224  PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283
                  SPSPVL                E  +  ++A L +P    T++++  S   +  
Sbjct: 261  SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 302

Query: 284  SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343
             S  + +P             SP    +  P L      S P+P +E      + P    
Sbjct: 303  ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 349

Query: 344  PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
                PL S T  I+E NG+  SE L    ES  E+      P    + I      E  L 
Sbjct: 350  ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 405

Query: 401  CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456
              P+P    ++P + P       T   +PP  P   PA A + +SP+     +  +EE+E
Sbjct: 406  GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 461

Query: 457  SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504
                   E+  E     E E++   EE+L  ++     +P+PA            Q+A++
Sbjct: 462  E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 510

Query: 505  VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563
            VPK  +K K+  +  +E +   L+   E   ++ +V        + G  PE + S +  +
Sbjct: 511  VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 566

Query: 564  VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623
             +  +E  +  E   + AE++  GE                 + +K + WKP + E KK+
Sbjct: 567  PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 611

Query: 624  YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680
            YDREFLL FQF+ A +QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+
Sbjct: 612  YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 669

Query: 681  FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728
            FA+ GR T   RG P              +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 670  FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 729

Query: 729  AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783
            AE AWKPS KR     D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 730  AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 789

Query: 784  TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843
            TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQK
Sbjct: 790  TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 849

Query: 844  EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903
            EFEKDK DD+VFEKKQKE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 850  EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 909

Query: 904  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963
            MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 910  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 969

Query: 964  KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021
            KTSSRIRFMLQDV+DLR  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +
Sbjct: 970  KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 1029

Query: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071
            KRR          G+  VD+GGWNTV  +K SR +D S+  KITKP +ID   QL     
Sbjct: 1030 KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 1089

Query: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127
              SWGKGSSGG+ A  +D    A R + S+LNRFSALQ   P+ ST       D+RR + 
Sbjct: 1090 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 1141

Query: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176
             R S+ RE+ +K       R     RGG   D LD           ++  EE+ RE    
Sbjct: 1142 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200

Query: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236
             + L     +  +         RE+A P +S +    KAALSEEELE+KSK+II+E+LH+
Sbjct: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1256

Query: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296
            ND KEA+QCV+EL +  LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   ++
Sbjct: 1257 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1316

Query: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356
            +G  E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL
Sbjct: 1317 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1376

Query: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416
             EIL LLCK M  KKVG LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA 
Sbjct: 1377 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1433

Query: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476
             ++ L +EEL ++LEKL+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1434 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1492

Query: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536
             + +  RVD AV+K R  +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1493 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1550

Query: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
            DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1551 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 1273 bits (3294), Expect = 0.0
 Identities = 808/1669 (48%), Positives = 1006/1669 (60%), Gaps = 194/1669 (11%)

Query: 1    MNSQPQTRSPFFQRPQIQPPR--ATIPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMP 57
            MN+  Q R  F+   + QPP   A+   S+   RPG   P A VY A   +MM+    + 
Sbjct: 41   MNTPSQPRQHFYPS-RAQPPSSAASRVQSAAPARPG---PAAHVYPAGSQVMMIPS-QIS 95

Query: 58   YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP 117
            YP  QG  Y   Q R +   YV P QQYPVQP  PG FYPG  P +F   Y   +YP+Q 
Sbjct: 96   YPASQGAYYIPGQGRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQG 150

Query: 118  VYQSAPIIVPT---QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172
            V Q    + P      QPP    KRE+KTIRIRDPNQGGKDITEEIMSG           
Sbjct: 151  VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA---------- 200

Query: 173  RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223
            R  STPTPPQ    L  Q    +P V   V      + A +A    +        E +P 
Sbjct: 201  RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 260

Query: 224  PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283
                  SPSPVL                E  +  ++A L +P    T++++  S   +  
Sbjct: 261  SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 302

Query: 284  SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343
             S  + +P             SP    +  P L      S P+P +E      + P    
Sbjct: 303  ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 349

Query: 344  PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
                PL S T  I+E NG+  SE L    ES  E+      P    + I      E  L 
Sbjct: 350  ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 405

Query: 401  CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456
              P+P    ++P + P       T   +PP  P   PA A + +SP+     +  +EE+E
Sbjct: 406  GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 461

Query: 457  SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504
                   E+  E     E E++   EE+L  ++     +P+PA            Q+A++
Sbjct: 462  E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 510

Query: 505  VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563
            VPK  +K K+  +  +E +   L+   E   ++ +V        + G  PE + S +  +
Sbjct: 511  VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 566

Query: 564  VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623
             +  +E  +  E   + AE++  GE                 + +K + WKP + E KK+
Sbjct: 567  PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 611

Query: 624  YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680
            YDREFLL FQF+ A +QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+
Sbjct: 612  YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 669

Query: 681  FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728
            FA+ GR T   RG P              +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 670  FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 729

Query: 729  AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783
            AE AWKPS KR     D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 730  AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 789

Query: 784  TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843
            TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQK
Sbjct: 790  TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 849

Query: 844  EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903
            EFEKDK DD+VFEKKQKE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 850  EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 909

Query: 904  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963
            MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 910  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 969

Query: 964  KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021
            KTSSRIRFMLQDV+DLR  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +
Sbjct: 970  KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 1029

Query: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071
            KRR          G+  VD+GGWNTV  +K SR +D S+  KITKP +ID   QL     
Sbjct: 1030 KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 1089

Query: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127
              SWGKGSSGG+ A  +D    A R + S+LNRFSALQ   P+ ST       D+RR + 
Sbjct: 1090 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 1141

Query: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176
             R S+ RE+ +K       R     RGG   D LD           ++  EE+ RE    
Sbjct: 1142 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200

Query: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236
             + L     +  +         RE+A P +S +    KAALSEEELE+KSK+II+E+LH+
Sbjct: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1256

Query: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296
            ND KEA+QCV+EL +  LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   ++
Sbjct: 1257 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1316

Query: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356
            +G  E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL
Sbjct: 1317 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1376

Query: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416
             EIL LLCK M  KKVG LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA 
Sbjct: 1377 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1433

Query: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476
             ++ L +EEL ++LEKL+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1434 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1492

Query: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536
             + +  RVD AV+K R  +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1493 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1550

Query: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
            DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1551 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
            isoform 2 [Homo sapiens]
          Length = 1512

 Score = 1259 bits (3258), Expect = 0.0
 Identities = 786/1609 (48%), Positives = 978/1609 (60%), Gaps = 186/1609 (11%)

Query: 58   YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP 117
            YP  QG  Y   Q R +   YV P QQYPVQP  PG FYPG  P +F   Y   +YP+Q 
Sbjct: 9    YPASQGAYYIPGQGRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQG 63

Query: 118  VYQSAPIIVPT---QQQPP--PAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172
            V Q    + P      QPP    KRE+KTIRIRDPNQGGKDITEEIMSG           
Sbjct: 64   VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSG----------A 113

Query: 173  RPTSTPTPPQ-------QLPSQVPEHSPVVY--GTVESAHLAASTPVTAASDQKQEEKPK 223
            R  STPTPPQ       Q   + P+ + +V      + A +A    +        E +P 
Sbjct: 114  RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 173

Query: 224  PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283
                  SPSPVL                E  +  ++A L +P    T++++  S   +  
Sbjct: 174  SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 215

Query: 284  SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343
             S  + +P             SP    +  P L      S P+P +E      + P    
Sbjct: 216  ISRETGEPY----------RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP---- 261

Query: 344  PNDIPLVSSTNLINEINGV--SEKLS-ATESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
                PL S T  I+E NG+  SE L    ES  E+      P    + I      E  L 
Sbjct: 262  ---TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 318

Query: 401  CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456
              P+P    ++P + P       T   +PP  P   PA A + +SP+     +  +EE+E
Sbjct: 319  GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 374

Query: 457  SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504
                   E+  E     E E++   EE+L  ++     +P+PA            Q+A++
Sbjct: 375  ------EEEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 423

Query: 505  VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDL-KK 563
            VPK  +K K+  +  +E +   L+   E   ++ +V    Q        PE + S +  +
Sbjct: 424  VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEV--ENQPPAGSNPGPESEGSGVPPR 479

Query: 564  VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623
             +  +E  +  E   + AE++  GE                 + +K + WKP + E KK+
Sbjct: 480  PEEADETWDSKEDKIHNAENIQPGE---------------QKYEYKSDQWKPLNLEEKKR 524

Query: 624  YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680
            YDREFLL FQF+ A +QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+
Sbjct: 525  YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 582

Query: 681  FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728
            FA+ GR T   RG P              +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 583  FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 642

Query: 729  AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783
            AE AWKPS KR     D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 643  AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 702

Query: 784  TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843
            TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQK
Sbjct: 703  TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 762

Query: 844  EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903
            EFEKDK DD+VFEKKQKE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 763  EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 822

Query: 904  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963
            MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 823  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 882

Query: 964  KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021
            KTSSRIRFMLQDV+DLR  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +
Sbjct: 883  KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 942

Query: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071
            KRR          G+  VD+GGWNTV  +K SR +D S+  KITKP +ID   QL     
Sbjct: 943  KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 1002

Query: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127
              SWGKGSSGG+ A  +D    A R + S+LNRFSALQ   P+ ST       D+RR + 
Sbjct: 1003 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 1054

Query: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176
             R S+ RE+ +K       R     RGG   D LD           ++  EE+ RE    
Sbjct: 1055 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1113

Query: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236
             + L     +  +         RE+A P +S +    KAALSEEELE+KSK+II+E+LH+
Sbjct: 1114 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1169

Query: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296
            ND KEA+QCV+EL +  LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   ++
Sbjct: 1170 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1229

Query: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356
            +G  E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL
Sbjct: 1230 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1289

Query: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416
             EIL LLCK M  KKVG LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA 
Sbjct: 1290 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1346

Query: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476
             ++ L +EEL ++LEKL+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1347 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1405

Query: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536
             + +  RVD AV+K R  +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1406 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1463

Query: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
            DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1464 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1512


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
            isoform 3 [Homo sapiens]
          Length = 1435

 Score = 1214 bits (3142), Expect = 0.0
 Identities = 754/1533 (49%), Positives = 941/1533 (61%), Gaps = 178/1533 (11%)

Query: 131  QPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQ------ 182
            QPP    KRE+KTIRIRDPNQGGKDITEEIMSG           R  STPTPPQ      
Sbjct: 3    QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSG----------ARTASTPTPPQTGGGLE 52

Query: 183  -QLPSQVPEHSPVVY--GTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVL 239
             Q   + P+ + +V      + A +A    +        E +P       SPSPVL    
Sbjct: 53   PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL---- 108

Query: 240  SGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDD 299
                        E  +  ++A L +P    T++++  S   +   S  + +P        
Sbjct: 109  ------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTPISRETGEPY------- 147

Query: 300  RCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 SP    +  P L      S P+P +E      + P        PL S T  I+E 
Sbjct: 148  ---RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP-------TPLASHTVEIHEP 197

Query: 360  NGV--SEKLS-ATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAP----ITPSTVP 412
            NG+  SE L    ES  E+      P    + I      E  L   P+P    ++P + P
Sbjct: 198  NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP 257

Query: 413  SFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNK 472
                   T   +PP  P   PA A + +SP+     +  +EE+E       E+  E    
Sbjct: 258  EEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE------EEEEGEAGEA 307

Query: 473  IEVEADGQTEEILDSQNLNSRRSPVPA------------QIAITVPKTWKKPKDRTRTTE 520
             E E++   EE+L  ++     +P+PA            Q+A++VPK  +K K+  +  +
Sbjct: 308  GEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNK--K 360

Query: 521  EMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDL-KKVKAVEENGEEAEPVRN 579
            E +   L+   E   ++ +V    Q        PE + S +  + +  +E  +  E   +
Sbjct: 361  EAVGDLLDAFKEANPAVPEV--ENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIH 418

Query: 580  GAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACI 639
             AE++  GE                 + +K + WKP + E KK+YDREFLL FQF+ A +
Sbjct: 419  NAENIQPGE---------------QKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 463

Query: 640  QKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPAFADFGRQTPGGRGVPL 696
            QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+FA+ GR T   RG P 
Sbjct: 464  QKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPR 521

Query: 697  -----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKKAENAWKPSQKR----- 739
                         +G RRSQ G R+EPRKII TV + ED+ L KAE AWKPS KR     
Sbjct: 522  GGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADK 581

Query: 740  DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFEKA 799
            D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +DTEERLKGVIDL+FEKA
Sbjct: 582  DRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKA 641

Query: 800  IDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQ 859
            I EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQKEFEKDK DD+VFEKKQ
Sbjct: 642  ISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQ 701

Query: 860  KELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLK 919
            KE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLKMLTEAIMHDCVVKLLK
Sbjct: 702  KEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLK 761

Query: 920  NHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDL 979
            NHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+KTSSRIRFMLQDV+DL
Sbjct: 762  NHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDL 821

Query: 980  RLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--EKRR---------PGVQ 1028
            R  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +KRR          G+ 
Sbjct: 822  RGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLP 881

Query: 1029 RVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQLGSWGKGSSGGAKASE 1087
             VD+GGWNTV  +K SR +D S+  KITKP +ID   QL       SWGKGSSGG+ A  
Sbjct: 882  LVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKP 941

Query: 1088 TD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPS 1143
            +D    A R + S+LNRFSALQ   P+ ST       D+RR +  R S+ RE+ +K    
Sbjct: 942  SDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VVQRSSLSRERGEK-AGD 992

Query: 1144 ATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLETVKQLTGGVDVERNSTE 1192
               R     RGG   D LD           ++  EE+ RE     + L     +  +   
Sbjct: 993  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1052

Query: 1193 AERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQ 1252
                  RE+A P +S +    KAALSEEELE+KSK+II+E+LH+ND KEA+QCV+EL + 
Sbjct: 1053 GRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASP 1108

Query: 1253 GLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAID 1312
             LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   +++G  E LELA+DM ID
Sbjct: 1109 SLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEID 1168

Query: 1313 IPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKV 1372
            IPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL EIL LLCK M  KKV
Sbjct: 1169 IPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKV 1228

Query: 1373 GALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEK 1432
            G LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA  ++ L +EEL ++LEK
Sbjct: 1229 GTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAPGQRALPSEELNRQLEK 1285

Query: 1433 LIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQR 1492
            L+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII + +  RVD AV+K R
Sbjct: 1286 LLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFE-TPLRVDVAVLKAR 1343

Query: 1493 VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESS 1552
              +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LYDE+V+ EDAFY WESS
Sbjct: 1344 AKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESS 1402

Query: 1553 KDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
            KDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1403 KDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
            isoform 4 [Homo sapiens]
          Length = 1403

 Score = 1171 bits (3029), Expect = 0.0
 Identities = 726/1489 (48%), Positives = 912/1489 (61%), Gaps = 166/1489 (11%)

Query: 173  RPTSTPTPPQ-------QLPSQVPEHSPVVY--GTVESAHLAASTPVTAASDQKQEEKPK 223
            R  STPTPPQ       Q   + P+ + +V      + A +A    +        E +P 
Sbjct: 5    RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 64

Query: 224  PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283
                  SPSPVL                E  +  ++A L +P    T++++  S   +  
Sbjct: 65   SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 106

Query: 284  SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343
             S  + +P             SP    +  P L      S P+P +E      + P    
Sbjct: 107  ISRETGEPY----------RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP---- 152

Query: 344  PNDIPLVSSTNLINEINGV--SEKLS-ATESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
                PL S T  I+E NG+  SE L    ES  E+      P    + I      E  L 
Sbjct: 153  ---TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 209

Query: 401  CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456
              P+P    ++P + P       T   +PP  P   PA A + +SP+     +  +EE+E
Sbjct: 210  GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 265

Query: 457  SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504
                   E+  E     E E++   EE+L  ++     +P+PA            Q+A++
Sbjct: 266  ------EEEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 314

Query: 505  VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDL-KK 563
            VPK  +K K+  +  +E +   L+   E   ++ +V    Q        PE + S +  +
Sbjct: 315  VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEV--ENQPPAGSNPGPESEGSGVPPR 370

Query: 564  VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623
             +  +E  +  E   + AE++  GE                 + +K + WKP + E KK+
Sbjct: 371  PEEADETWDSKEDKIHNAENIQPGE---------------QKYEYKSDQWKPLNLEEKKR 415

Query: 624  YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680
            YDREFLL FQF+ A +QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+
Sbjct: 416  YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 473

Query: 681  FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728
            FA+ GR T   RG P              +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 474  FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 533

Query: 729  AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783
            AE AWKPS KR     D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 534  AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 593

Query: 784  TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843
            TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQK
Sbjct: 594  TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 653

Query: 844  EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903
            EFEKDK DD+VFEKKQKE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 654  EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 713

Query: 904  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963
            MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 714  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 773

Query: 964  KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021
            KTSSRIRFMLQDV+DLR  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +
Sbjct: 774  KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 833

Query: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071
            KRR          G+  VD+GGWNTV  +K SR +D S+  KITKP +ID   QL     
Sbjct: 834  KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 893

Query: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127
              SWGKGSSGG+ A  +D    A R + S+LNRFSALQ   P+ ST       D+RR + 
Sbjct: 894  RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 945

Query: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176
             R S+ RE+ +K       R     RGG   D LD           ++  EE+ RE    
Sbjct: 946  QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1004

Query: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236
             + L     +  +         RE+A P +S +    KAALSEEELE+KSK+II+E+LH+
Sbjct: 1005 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1060

Query: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296
            ND KEA+QCV+EL +  LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   ++
Sbjct: 1061 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1120

Query: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356
            +G  E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL
Sbjct: 1121 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1180

Query: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416
             EIL LLCK M  KKVG LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA 
Sbjct: 1181 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1237

Query: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476
             ++ L +EEL ++LEKL+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1238 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1296

Query: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536
             + +  RVD AV+K R  +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1297 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1354

Query: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
            DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1355 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1403


>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
            isoform 2 [Homo sapiens]
          Length = 869

 Score =  190 bits (483), Expect = 8e-48
 Identities = 119/293 (40%), Positives = 179/293 (61%), Gaps = 34/293 (11%)

Query: 733  WKP--SQKRD--SQADDPENIKTQE--LFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEE 786
            W P  S +RD  S A++  N K +   +FRKVR ILNKLTP+ F++L  ++  + V+++ 
Sbjct: 50   WIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKL 109

Query: 787  RLKGVIDLVFEKAIDEPSFSVAYANMCRCLV----TLKVPMAD-KPGN--TVNFRKLLLN 839
             LKGVI L+ +KA++EP +S  YA +C  L         P A+ +PG   +  FR+LL++
Sbjct: 110  ILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLIS 169

Query: 840  RCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGEL 899
            + Q EFE    + DV++K++  L     PEE        EE +  A+ + +GNIKFIGEL
Sbjct: 170  KLQDEFENRTRNVDVYDKRENPL----LPEE--------EEQRAIAKIKMLGNIKFIGEL 217

Query: 900  FKLKMLTEAIMHDCVVKLLKNHDE-------ESLECLCRLLTTIGKDLDFEKAKPRMDQY 952
             KL ++ E+I+H C+  LL+           E LECLC+++ T+G  LD E+AK  MDQY
Sbjct: 218  GKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQY 277

Query: 953  FNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRA--DQGPKTIEQIHKEA 1003
            F +M  ++  ++  +RIRF+LQD ++LR  +WV R+A  D GPKTI QI ++A
Sbjct: 278  FARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDA 330



 Score =  103 bits (257), Expect = 1e-21
 Identities = 95/385 (24%), Positives = 172/385 (44%), Gaps = 39/385 (10%)

Query: 1218 SEEELERKSKSIIDEFLHINDFKEAMQCVEELNA-QGLLHVFVRVGVESTLERSQITRDH 1276
            S+EEL + +++++ E+L+  +  EA+  V E+ A +  L   +   +  +L+RS   ++ 
Sbjct: 502  SKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEK 561

Query: 1277 MGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMR 1336
               L+  L Q    +  +F + F   L+    + +DIP +  YLA+     +    +S+ 
Sbjct: 562  ASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSIS 621

Query: 1337 ELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNF 1396
            EL    ++PL   G    L    L  L K    + +  L++++ ++ +  LPE       
Sbjct: 622  EL----AQPL-ESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPE------- 669

Query: 1397 LLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAND---EQIFDWVEANLD 1453
                    I+ +     E L  K LS      +LEK +++    D   + I+ W++ N+ 
Sbjct: 670  --------IDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNIS 721

Query: 1454 E--------IQMSSPTFLRALMTAVCKAAIIADSST------FRVDTAVIKQRVPILLKY 1499
                     + +   +FL+ + + V   +   DSS+         +  ++    P++ K+
Sbjct: 722  PKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKF 781

Query: 1500 LDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQN 1559
            L    + ++ ALYALQ      + P  +L  FF   YD E+I E+AF  W+      E  
Sbjct: 782  LHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-ITQEFP 840

Query: 1560 GKGVALKSVTAFFTWLREAEEESED 1584
            GKG AL  V  + TWL  AEEE  +
Sbjct: 841  GKGKALFQVNQWLTWLETAEEEESE 865


>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
            isoform 1 [Homo sapiens]
          Length = 907

 Score =  190 bits (483), Expect = 8e-48
 Identities = 119/293 (40%), Positives = 179/293 (61%), Gaps = 34/293 (11%)

Query: 733  WKP--SQKRD--SQADDPENIKTQE--LFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEE 786
            W P  S +RD  S A++  N K +   +FRKVR ILNKLTP+ F++L  ++  + V+++ 
Sbjct: 50   WIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKL 109

Query: 787  RLKGVIDLVFEKAIDEPSFSVAYANMCRCLV----TLKVPMAD-KPGN--TVNFRKLLLN 839
             LKGVI L+ +KA++EP +S  YA +C  L         P A+ +PG   +  FR+LL++
Sbjct: 110  ILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLIS 169

Query: 840  RCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGEL 899
            + Q EFE    + DV++K++  L     PEE        EE +  A+ + +GNIKFIGEL
Sbjct: 170  KLQDEFENRTRNVDVYDKRENPL----LPEE--------EEQRAIAKIKMLGNIKFIGEL 217

Query: 900  FKLKMLTEAIMHDCVVKLLKNHDE-------ESLECLCRLLTTIGKDLDFEKAKPRMDQY 952
             KL ++ E+I+H C+  LL+           E LECLC+++ T+G  LD E+AK  MDQY
Sbjct: 218  GKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQY 277

Query: 953  FNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRA--DQGPKTIEQIHKEA 1003
            F +M  ++  ++  +RIRF+LQD ++LR  +WV R+A  D GPKTI QI ++A
Sbjct: 278  FARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDA 330



 Score =  103 bits (257), Expect = 1e-21
 Identities = 95/385 (24%), Positives = 172/385 (44%), Gaps = 39/385 (10%)

Query: 1218 SEEELERKSKSIIDEFLHINDFKEAMQCVEELNA-QGLLHVFVRVGVESTLERSQITRDH 1276
            S+EEL + +++++ E+L+  +  EA+  V E+ A +  L   +   +  +L+RS   ++ 
Sbjct: 540  SKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEK 599

Query: 1277 MGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMR 1336
               L+  L Q    +  +F + F   L+    + +DIP +  YLA+     +    +S+ 
Sbjct: 600  ASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSIS 659

Query: 1337 ELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNF 1396
            EL    ++PL   G    L    L  L K    + +  L++++ ++ +  LPE       
Sbjct: 660  EL----AQPL-ESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPE------- 707

Query: 1397 LLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAND---EQIFDWVEANLD 1453
                    I+ +     E L  K LS      +LEK +++    D   + I+ W++ N+ 
Sbjct: 708  --------IDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNIS 759

Query: 1454 E--------IQMSSPTFLRALMTAVCKAAIIADSST------FRVDTAVIKQRVPILLKY 1499
                     + +   +FL+ + + V   +   DSS+         +  ++    P++ K+
Sbjct: 760  PKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKF 819

Query: 1500 LDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQN 1559
            L    + ++ ALYALQ      + P  +L  FF   YD E+I E+AF  W+      E  
Sbjct: 820  LHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-ITQEFP 878

Query: 1560 GKGVALKSVTAFFTWLREAEEESED 1584
            GKG AL  V  + TWL  AEEE  +
Sbjct: 879  GKGKALFQVNQWLTWLETAEEEESE 903


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 145/606 (23%), Positives = 217/606 (35%), Gaps = 111/606 (18%)

Query: 9   SPFFQRPQIQPPRATIPNS----SPSIRPGAQTPTAVYQANQHIMMVNHL-PMPYPVPQG 63
           SP   RP   P +A+   +    +P  R   Q    V QA    ++   L  +P P P+G
Sbjct: 295 SPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRG 354

Query: 64  ---PQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQ 120
              P    P  R   PP++   Q  P + P P P    PGP         P   S+ V  
Sbjct: 355 TPKPSEGTPAPRKD-PPWITLVQAEPKKKPAPLPPSSSPGP---------PSQDSRQVEN 404

Query: 121 SAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP 180
                V   Q  P A  E K     +P +  ++  EE      S   +P +G P STP  
Sbjct: 405 GGTEEV--AQPSPTASLESKPY---NPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKS 459

Query: 181 PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS 240
                   P  SP           +AS     AS     E P       +PSP L +   
Sbjct: 460 LHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPS-----ATPSPALSV--- 511

Query: 241 GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR 300
                 E  +SE+ +  + AEL  PP+    SS     + AP +          +++   
Sbjct: 512 ------ESLSSESASQTAGAELLEPPAVPKSSS--EPAVHAPGTPGNPVSLSTNSSLASS 563

Query: 301 CELSSPREDTIP--IPSLTSCTE-TSDPLPTNENDDDICKKPCSVA-PNDIPLVSSTNLI 356
            EL  PR + +P   P L   T  +S P P          KPCS A P  + LV   + +
Sbjct: 564 GELVEPRVEQMPQASPGLAPRTRGSSGPQPA---------KPCSGATPTPLLLVGDRSPV 614

Query: 357 NEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAP-ITPSTVPSFP 415
                 S +L    S                   ENP         P+P  +P+T  +  
Sbjct: 615 PSPGSSSPQLQVKSS-----------------CKENPFNRK-----PSPAASPATKKATK 652

Query: 416 PTPPTPPASPPH-TPVIVPAAATTVSSPSAAI-----TVQRVLEE--------DESIRTC 461
            + P  P +P H  P+I          P   I     T++R L+         +E +R  
Sbjct: 653 GSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGG 712

Query: 462 LSEDAKE----------IQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKK 511
           L+E  ++           +  + V  + +   +   QNL  R++ V  ++   + K  K 
Sbjct: 713 LNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKD 772

Query: 512 PKDRTRTTEEMLEAELELKAEEELSI------DKVLESEQDKMSQG------FHPERDPS 559
             +  R  E++L  EL    E+  +I      D+  E E+DKM +       F  E +P 
Sbjct: 773 WTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPE 832

Query: 560 DLKKVK 565
             KK K
Sbjct: 833 GKKKGK 838


>gi|34452730 poly(A) binding protein interacting protein 1 isoform 3
           [Homo sapiens]
          Length = 367

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 65/270 (24%), Positives = 122/270 (45%), Gaps = 55/270 (20%)

Query: 736 SQKRDSQADDPENIKTQELFRKVRSILNKLTPQM------FNQLMKQVSGLTVDTEERLK 789
           S   +S  D  E+  T  L   V+  LN LT Q         Q  + ++G  V T++ L+
Sbjct: 30  SSYTESYEDGCEDYPT--LSEYVQDFLNHLTEQPGSFETEIEQFAETLNGC-VTTDDALQ 86

Query: 790 GVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDK 849
            +++L++++A   P+FS   A +C  L +  + ++ + GN   FR+LLL RC+ E+E   
Sbjct: 87  ELVELIYQQATSIPNFSYMGARLCNYL-SHHLTISPQSGN---FRQLLLQRCRTEYE--- 139

Query: 850 ADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF-KLKM---- 904
                                   + D+  +  +  R+R    + F+GEL+  L++    
Sbjct: 140 ------------------------VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTN 175

Query: 905 -------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFN 954
                  + +  + + +  L  N  +++L C  +LL   G  L+    EK K  M++   
Sbjct: 176 GQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQ 235

Query: 955 QMEKIVKERKTSSRIRFMLQDVIDLRLCNW 984
           ++E +V +   S  ++ ML  +++LR  NW
Sbjct: 236 RIENVVLDANCSRDVKQMLLKLVELRSSNW 265


>gi|33386693 poly(A) binding protein interacting protein 1 isoform 2
           [Homo sapiens]
          Length = 400

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 65/270 (24%), Positives = 122/270 (45%), Gaps = 55/270 (20%)

Query: 736 SQKRDSQADDPENIKTQELFRKVRSILNKLTPQM------FNQLMKQVSGLTVDTEERLK 789
           S   +S  D  E+  T  L   V+  LN LT Q         Q  + ++G  V T++ L+
Sbjct: 63  SSYTESYEDGCEDYPT--LSEYVQDFLNHLTEQPGSFETEIEQFAETLNGC-VTTDDALQ 119

Query: 790 GVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDK 849
            +++L++++A   P+FS   A +C  L +  + ++ + GN   FR+LLL RC+ E+E   
Sbjct: 120 ELVELIYQQATSIPNFSYMGARLCNYL-SHHLTISPQSGN---FRQLLLQRCRTEYE--- 172

Query: 850 ADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF-KLKM---- 904
                                   + D+  +  +  R+R    + F+GEL+  L++    
Sbjct: 173 ------------------------VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTN 208

Query: 905 -------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFN 954
                  + +  + + +  L  N  +++L C  +LL   G  L+    EK K  M++   
Sbjct: 209 GQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQ 268

Query: 955 QMEKIVKERKTSSRIRFMLQDVIDLRLCNW 984
           ++E +V +   S  ++ ML  +++LR  NW
Sbjct: 269 RIENVVLDANCSRDVKQMLLKLVELRSSNW 298


>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
           [Homo sapiens]
          Length = 479

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 65/270 (24%), Positives = 122/270 (45%), Gaps = 55/270 (20%)

Query: 736 SQKRDSQADDPENIKTQELFRKVRSILNKLTPQM------FNQLMKQVSGLTVDTEERLK 789
           S   +S  D  E+  T  L   V+  LN LT Q         Q  + ++G  V T++ L+
Sbjct: 142 SSYTESYEDGCEDYPT--LSEYVQDFLNHLTEQPGSFETEIEQFAETLNGC-VTTDDALQ 198

Query: 790 GVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDK 849
            +++L++++A   P+FS   A +C  L +  + ++ + GN   FR+LLL RC+ E+E   
Sbjct: 199 ELVELIYQQATSIPNFSYMGARLCNYL-SHHLTISPQSGN---FRQLLLQRCRTEYE--- 251

Query: 850 ADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF-KLKM---- 904
                                   + D+  +  +  R+R    + F+GEL+  L++    
Sbjct: 252 ------------------------VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTN 287

Query: 905 -------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFN 954
                  + +  + + +  L  N  +++L C  +LL   G  L+    EK K  M++   
Sbjct: 288 GQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQ 347

Query: 955 QMEKIVKERKTSSRIRFMLQDVIDLRLCNW 984
           ++E +V +   S  ++ ML  +++LR  NW
Sbjct: 348 RIENVVLDANCSRDVKQMLLKLVELRSSNW 377


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 99/401 (24%), Positives = 144/401 (35%), Gaps = 48/401 (11%)

Query: 59  PVPQGPQYCIPQY----RHSGPPYVGPPQQYPVQPPGPG--PFYPGPGPGDFPNAYGTPF 112
           P P+G Q   P      R    P +GP    P+  P P      P P P +         
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331

Query: 113 YPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172
            PS P+    P+  P     PP+ +   +     P+Q    +T   M    S    PPI 
Sbjct: 332 PPSPPLATPLPL-APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390

Query: 173 RPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASD-------QKQEEKPKPD 225
            P S  +P  Q P      SP+   ++++     S  + A          Q Q     P 
Sbjct: 391 VPHSLTSPSLQAPP-----SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445

Query: 226 PVLKSP--SPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPT-TVSSVARSTIAAP 282
               +P  SP L+  LS        QTS + A+  ++  PL   P   +SS+A  +  AP
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPL-QTSLSPAVSPLSS-PLTIHPLQALSSLASHSPQAP 503

Query: 283 TSSALSSQPIFTTAIDDRCELSSPRED--TIPIPSLTSCTE-----TSDPLPTNENDDDI 335
            SS L   P+ T +      L +P     T P+ +L S         S PL T   +   
Sbjct: 504 LSS-LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP 562

Query: 336 CKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPE 395
           C  PC +     PL +                 T S +     +  P      +   P  
Sbjct: 563 CPAPCPLQAPPSPLTTPP-------------PETPSSIATPPPQAPPALASPPLQGLPSP 609

Query: 396 EMKLECIPAPITPSTVPSFPP--TPPTPPASPPHTPVIVPA 434
            +     P P  P  + + PP   PP+PPASPP +P+  P+
Sbjct: 610 PLSPLATPPPQAPPXL-ALPPLQAPPSPPASPPLSPLATPS 649



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 106/475 (22%), Positives = 168/475 (35%), Gaps = 83/475 (17%)

Query: 3   SQPQTRS-PFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVP 61
           SQP+ +     + PQ+ PPR    +++P++ P + +P A    +           P P P
Sbjct: 270 SQPKPKGLQALRPPQVTPPRK---DAAPALGPLSSSPLATPSPS------GTKARPVPPP 320

Query: 62  QGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPG--------PFYPGPGPGDFPNAYGTPFY 113
                 +P      PP   P    P+ PP P         P  P   P   P +  TP  
Sbjct: 321 DNAATPLPATLPPSPPLATP---LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377

Query: 114 PSQPVYQSAPIIV-------PTQQQPPPA---KREKKTIRIRDPNQGGKDITEEIMSGGG 163
            + P  Q+ P I        P+ Q PP        + T  +  P          +     
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437

Query: 164 SRNPTPPIGRPTSTP--TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEK 221
             + T P  RP STP  +PP Q P  +P  SP +  ++  A    S+P+T    Q     
Sbjct: 438 QASLTSP-SRPASTPPDSPPLQAPLSLPA-SPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495

Query: 222 PKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAA 281
               P     +P+  L++            ET + ++   L  PP+  T   +      A
Sbjct: 496 ASHSP----QAPLSSLIMP---------PLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542

Query: 282 PTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPL--PTNENDDDICKKP 339
           P     +S P           L++P  +T P P+         PL  P  E    I   P
Sbjct: 543 PPPLQTASAP-----------LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591

Query: 340 CSVAPNDIPLVSSTNL-------INEINGVSEKLSATESIVEIVKQEVLPLTLELEILEN 392
               P   P ++S  L       ++ +     +     ++  +      P +  L  L  
Sbjct: 592 ----PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647

Query: 393 P----PEEMKLECIPAPITPSTVPSFPPTPPTP-PASPPHTPVIVPAAATTVSSP 442
           P    P  + +  + AP +P      PP+PP   P SPP +P + P+A     +P
Sbjct: 648 PSPQAPNALAVHLLQAPFSP------PPSPPVQAPFSPPASPPVSPSATPPSQAP 696



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 74/293 (25%), Positives = 101/293 (34%), Gaps = 64/293 (21%)

Query: 9   SPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCI 68
           SP  Q P   PP +  P  SPS  P +Q P ++       + V   P   P P  P    
Sbjct: 670 SPPVQAP-FSPPAS--PPVSPSATPPSQAPPSLAAPP---LQVPPSPPASP-PMSPSATP 722

Query: 69  PQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPT 128
           P    + PP   PP Q P  PP   P  P   P            P  P   +AP   P 
Sbjct: 723 PP--QAPPPLAAPPLQVPPSPPASPPMSPSATPP-----------PRVPPLLAAP---PL 766

Query: 129 QQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQV 188
           Q  P P      +   + P Q    +             TPP+    + P+PP   P Q 
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALA------------TPPL---QALPSPPASFPGQA 811

Query: 189 PEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSP----------SPVLRLV 238
           P  SP           +AS P++  +       P+  PVL +P          SP L+  
Sbjct: 812 P-FSP-----------SASLPMSPLA----TPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855

Query: 239 LSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQP 291
                   +   S     +++A  P PP   + SS       A  SS+ +S P
Sbjct: 856 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 92/406 (22%), Positives = 133/406 (32%), Gaps = 73/406 (17%)

Query: 91  GPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQ--------------QQPPPAK 136
           GP P  P P       A GT     +P   + P   PT+               +P PA 
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR-PPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 137 REKKTI-------RIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVP 189
           R + +          R  +     ++    SG  +R  TP      S P P      + P
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRPP 283

Query: 190 EHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPD--------PVLKSPSPVLRLVLSG 241
           + +P       +    +S+P+   S    + +P P         P    PSP L   L  
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL-- 341

Query: 242 EKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRC 301
                       +A  S+  LP PP+ T  S    S    P  +  S Q I    I    
Sbjct: 342 -----PLAPPSPSAPPSLQTLPSPPA-TPPSQAPPSMTTPPMQAPPSLQTI--PPIQVPH 393

Query: 302 ELSSPREDTIPIPSLTSCTETSDPL--PTNENDDDIC--------------KKPCSVAPN 345
            L+SP     P P   S  + +  L  PT +                     +P S  P+
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453

Query: 346 DIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLE----LEILENPPEEMKLEC 401
             PL +  +L       S  L    S+   V     PLT+     L  L +   +  L  
Sbjct: 454 SPPLQAPLSL-----PASPPLQT--SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506

Query: 402 IPAPITPSTVPSFPPTPPTPPAS---PP--HTPVIVPAAATTVSSP 442
           +  P   +     PP+  TPPAS   PP  + P + P    T S+P
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 98/486 (20%), Positives = 152/486 (31%), Gaps = 78/486 (16%)

Query: 1   MNSQPQTRSPFFQR-PQIQPPRATIPNSSPSIR-PGAQTPTAVYQANQHI----MMVNHL 54
           M + P    P  Q  P IQ P +    +SPS++ P +    +  QA   +    +   H 
Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSL---TSPSLQAPPSPLALSSLQATTSLGSPTLQATHS 428

Query: 55  PMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYP 114
            +     Q         R +  P   PP Q P+  P   P      P   P +     +P
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488

Query: 115 SQ-------------------PVYQSAPIIVPTQQQPPPAKREKKTIR----IRDP--NQ 149
            Q                   P  ++   + P   Q PPA      +     +  P    
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548

Query: 150 GGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAA--S 207
               +T   +       P P    P+   TPP + PS +    P     + S  L    S
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608

Query: 208 TPVTAASDQKQEEKPKP--DPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLP 265
            P++  +    +  P     P+   PSP     LS          +     V + + P  
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS--PLATPSPQAPNALAVHLLQAPFS 666

Query: 266 PSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDP 325
           P P+       S  A+P  S  ++ P           L++P     P P        S P
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPP-----SLAAPPLQVPPSPP------ASPP 715

Query: 326 LPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTL 385
           +  +         P +  P  +P              S   S   S        V PL  
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVP-------------PSPPASPPMSPSATPPPRVPPLLA 762

Query: 386 E--LEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAA---TTVS 440
              L++  +PP  +       P++P   P  PP  P   A+PP   +  P A+       
Sbjct: 763 APPLQVPPSPPASL-------PMSPLAKP--PPQAPPALATPPLQALPSPPASFPGQAPF 813

Query: 441 SPSAAI 446
           SPSA++
Sbjct: 814 SPSASL 819


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 83/375 (22%), Positives = 114/375 (30%), Gaps = 46/375 (12%)

Query: 81   PPQQYPVQPPGPGPFYPG-----PGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPA 135
            PP      PP   P  P      P P   P+   T      P    +P I  T   PP  
Sbjct: 1409 PPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTT 1468

Query: 136  KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVV 195
                 T     P       T    +   +  P+PP   P + P     LP       P  
Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTT 1528

Query: 196  YGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTA 255
              T        S P T            P     SP P                   TT 
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT----------PPPTTTP 1578

Query: 256  IVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPS 315
                   P PP+ TT +    +T + PT++  +  P  T +      ++ P   T   P+
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638

Query: 316  LTSC---TETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESI 372
             T     T T+ P PT          P +  P+  P +++T         S  ++ T S 
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSP-----PTTTTPS--PPITTTTTPPPTTTPSSPITTTPSP 1691

Query: 373  VEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIV 432
                     P T                   +PIT +T PS   TP     SPP T +  
Sbjct: 1692 PTTTMTTPSPTTTP----------------SSPITTTTTPSSTTTP-----SPPPTTMTT 1730

Query: 433  PAAATTVSSPSAAIT 447
            P+  TT S P+  +T
Sbjct: 1731 PSPTTTPSPPTTTMT 1745



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 93/447 (20%), Positives = 144/447 (32%), Gaps = 27/447 (6%)

Query: 19   PPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPY 78
            PP  T   ++ ++ P   TPT         +       P P P G Q        +    
Sbjct: 1895 PPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1953

Query: 79   VGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPPA 135
               P     Q P   P          P   GT    + P+  +    P   PT  Q P  
Sbjct: 1954 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2013

Query: 136  K--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEHS 192
                   T+       G +  T   ++   +  PTP P G  T T TP     +  P  +
Sbjct: 2014 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2073

Query: 193  PVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSE 252
            P    T  +  +  +T VT        + P   P+  + +       +G       QT  
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPT 2127

Query: 253  TTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS--- 304
            TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++   
Sbjct: 2128 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187

Query: 305  ----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEIN 360
                +    T PI + T+ T T  P  T            +V P   P  + T     I 
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 361  GVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT 420
              +  ++ T +          P+T    +   P           PIT +T  +  PT PT
Sbjct: 2248 -TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PT 2305

Query: 421  PPASPPHTPVIVPAAATTVSSPSAAIT 447
               +P  TP+      T   +P+   T
Sbjct: 2306 GTQTPTTTPITTTTTVTPTPTPTGTQT 2332



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2032 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2090

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2091 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2150

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2151 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 2264

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2324

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 2385 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 2442

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQT 2470



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2170 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2228

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2229 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2288

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 2402

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 2523 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 2580

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQT 2608



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2308 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2366

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2367 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2426

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 2487 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 2540

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2600

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 2661 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 2718

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQT 2746



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2446 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2504

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2505 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2564

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2565 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2624

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 2625 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 2678

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 2799 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 2856

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQT 2884



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2584 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2642

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2643 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 2816

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 2937 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 2994

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3022



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2722 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2781 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2840

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 2954

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3075 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3132

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3160



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2860 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2918

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 2919 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2978

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 2979 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3092

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3152

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3213 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3270

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3298



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 2998 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3057 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3116

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3230

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3290

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3351 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3408

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3436



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3136 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3195 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3254

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3368

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3428

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3489 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3546

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3574



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3274 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3333 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3392

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3506

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3566

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3627 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3684

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3712



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3412 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3470

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3471 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3644

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3704

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3765 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3822

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3850



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3550 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3608

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3609 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3782

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 3903 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 3960

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQT 3988



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 93/448 (20%), Positives = 144/448 (32%), Gaps = 27/448 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3688 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3747 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3866

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3867 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3920

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3980

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPP 419
               +  ++ T +          P+T    +   P           PIT +T  +  PT P
Sbjct: 4041 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-P 4098

Query: 420  TPPASPPHTPVIVPAAATTVSSPSAAIT 447
            T   +P  TP+      T   +P+   T
Sbjct: 4099 TGTQTPTTTPITTTTTVTPTPTPTGTQT 4126



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 96/466 (20%), Positives = 146/466 (31%), Gaps = 44/466 (9%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3711 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3769

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3770 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3829

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3830 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3943

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTP- 418
               +  ++ T +          P+T    +   P           PIT +T  +  PTP 
Sbjct: 4064 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122

Query: 419  -----------------PTPPASPPHTPVIVPAAATTVSSPSAAIT 447
                             PTP  +   TP   P   TT  +P+   T
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4168



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 96/466 (20%), Positives = 146/466 (31%), Gaps = 44/466 (9%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3734 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3852

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3853 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3912

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3966

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4026

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTP- 418
               +  ++ T +          P+T    +   P           PIT +T  +  PTP 
Sbjct: 4087 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4145

Query: 419  -----------------PTPPASPPHTPVIVPAAATTVSSPSAAIT 447
                             PTP  +   TP   P   TT  +P+   T
Sbjct: 4146 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4191



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 70/285 (24%), Positives = 100/285 (35%), Gaps = 30/285 (10%)

Query: 167  PTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDP 226
            P+PP   P+  PT    LP       P    T        S P+T  +       P P P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP-P 1457

Query: 227  VLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSA 286
            +  + +P                +  TT        P PP+ TT +    +T + PT++ 
Sbjct: 1458 ISTTTTP----------PPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 287  LSSQPIFTTAIDDRCELSSP-REDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPN 345
            + + P  TT +      S P    T P P+ T    T+ P+    +   +   P +  P+
Sbjct: 1508 I-TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL---PPTTTPS 1563

Query: 346  DIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIP-- 403
              P  ++T         S   + T S   I      P T       +PP        P  
Sbjct: 1564 PPPTTTTTP--PPTTTPSPPTTTTPSPPTITTTTPPPTT-----TPSPPTTTTTTPPPTT 1616

Query: 404  APITPSTVPSFPPT-----PPTPPASPPHTPVIVPAAATTVSSPS 443
             P  P+T P  PPT     PPT   SPP T    P   TT S P+
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 115/505 (22%), Positives = 162/505 (32%), Gaps = 101/505 (20%)

Query: 5    PQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGP 64
            P T +P        PP  T     P+  P   T T +        +    P   P P   
Sbjct: 1472 PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP---PTTTPSPPTT 1528

Query: 65   QYCIPQYRHSGPPYV--GPPQQYPVQPP-GPGPFYPGPGPGDFPNAYGTP---FYPSQPV 118
                P      PP     PP   P+ PP       P   P   P    TP     PS P 
Sbjct: 1529 TTTTP------PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582

Query: 119  YQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTP 178
              +      T   PPP            P+      T    +   S   T PI  PTST 
Sbjct: 1583 TTTPSPPTITTTTPPPTTT---------PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633

Query: 179  T-PPQQLPSQVPEHSPVVYGTVESAHLAASTP---VTAASDQKQEEKPKPDPVLKSPSPV 234
            T PP   PS  P  +     T   +    +TP   +T  +       P   P+  +PSP 
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS-SPITTTPSPP 1692

Query: 235  LRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFT 294
               + +            TT   S    P PP PTT+++ + +T  +P ++ +++ P  T
Sbjct: 1693 TTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP-PTTMTTPSPTTTPSPPTTTMTTLPPTT 1751

Query: 295  TAIDDRCELSSPREDTIPIPSLTSCTET--SDPLPTNENDDDICKKPC-------SVAPN 345
            T        SSP   T   PS+T  T +  S   PT       C   C       S  PN
Sbjct: 1752 T--------SSPLTTTPLPPSITPPTFSPFSTTTPTTP-----CVPLCNWTGWLDSGKPN 1798

Query: 346  DIPLVSSTNLINEING---------------------VSEKLSATESIVEIVKQE----- 379
                   T LI ++ G                     + + +    S+  I K E     
Sbjct: 1799 FHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPG 1858

Query: 380  -VLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPP------------ 426
             V+P+   L        E+ ++C      P+T+ +     PTPP + P            
Sbjct: 1859 GVIPMAFCLNY------EINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPT 1912

Query: 427  ----HTPVIVPAAATTVSSPSAAIT 447
                 TP   P   TT  +P+   T
Sbjct: 1913 PTGTQTPTTTPITTTTTVTPTPTPT 1937



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 92/413 (22%), Positives = 120/413 (29%), Gaps = 42/413 (10%)

Query: 25   PNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCI---PQYRHSGPPYVGP 81
            P ++PS  P + T                 P P   P  P       P      PP    
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461

Query: 82   PQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKT 141
                P   P P    P P     P    TP  P+       P   P+     P      T
Sbjct: 1462 TTPPPTTTPSPPTTTPSP-----PTT--TPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514

Query: 142  IRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVES 201
              +          T            TPP   PT+TP+PP   P   P  +  +  T   
Sbjct: 1515 TTLPPTTTPSPPTTT---------TTTPP---PTTTPSPPTTTPITPPTSTTTLPPTT-- 1560

Query: 202  AHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAE 261
                 S P T  +       P P P   +PSP      +          + TT       
Sbjct: 1561 ---TPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616

Query: 262  LPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTE 321
             P PP+ T ++    +T   PT++   S P  TT         SP   T P P +T+   
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPITT--- 1671

Query: 322  TSDPLPTNENDDDICKKPC-------SVAPNDIPLVSSTNLINEINGVSEKLSATESIVE 374
            T+ P PT      I   P        + +P   P    T      +  +     T     
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP 1731

Query: 375  IVKQEVLPLTLELEILENPPEEMKLECIPAP--ITPSTVPSFPPTPPTPPASP 425
                   P T  +  L        L   P P  ITP T   F  T PT P  P
Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 90/370 (24%), Positives = 114/370 (30%), Gaps = 60/370 (16%)

Query: 81   PPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKK 140
            PP   P  PP      P   P   P+   T      P    +P I  T   PPP      
Sbjct: 1401 PPTTTPSPPPTSTTTLP---PTTTPSPPTTTTTTPPPTTTPSPPITTTTT-PPPTTTPSP 1456

Query: 141  TIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVE 200
             I                     S   TPP   PT+TP+PP   PS  P  +P       
Sbjct: 1457 PI---------------------STTTTPP---PTTTPSPPTTTPSP-PTTTP------- 1484

Query: 201  SAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIA 260
                  S P T  +       P P        P     L          T+ TT   +  
Sbjct: 1485 ------SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTT 1538

Query: 261  ELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCT 320
              P PP+ T ++    +T   PT++   S P  TT         SP   T P P  T  T
Sbjct: 1539 --PSPPTTTPITPPTSTTTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPP-TITT 1593

Query: 321  ETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEV 380
             T  P  T          P    P   P   +T  I          ++T ++        
Sbjct: 1594 TTPPPTTTPSPPTTTTTTP---PPTTTPSPPTTTPITPP-------TSTTTLPPTTTPSP 1643

Query: 381  LPLTLELEILENPPEEMKLECIPAPITPSTVP---SFPPTPPTPPASPPHTPVIVPAAAT 437
             P T         P          PIT +T P   + P +P T   SPP T +  P+  T
Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703

Query: 438  TVSSPSAAIT 447
            T SSP    T
Sbjct: 1704 TPSSPITTTT 1713



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 93/460 (20%), Positives = 144/460 (31%), Gaps = 32/460 (6%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3757 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3815

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3816 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3875

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3876 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3935

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 3936 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 3989

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4049

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359
                 +    T PI + T+ T T  P  T            +V P   P  + T     I
Sbjct: 4050 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4109

Query: 360  NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPIT------PSTVPS 413
               +  ++ T +          P+T    +   P           PIT      P+  P+
Sbjct: 4110 T-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4168

Query: 414  FPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLE 453
               TP T P +   T    P    T + P    +   + E
Sbjct: 4169 GTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAE 4208



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 96/461 (20%), Positives = 145/461 (31%), Gaps = 43/461 (9%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3826 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3884

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3885 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3944

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3945 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4004

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 4005 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 4058

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 4059 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4118

Query: 305  -----SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPL---VSSTNLI 356
                 +    T PI + T+ T T  P  T            +V P   P      +T  I
Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4178

Query: 357  NEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEE---MKLECIPAPITPST--- 410
                 V+   + T +              EL     PPE           +P+T ST   
Sbjct: 4179 TTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 4238

Query: 411  ---------VPSFPPTPPTPPASPPHTPVIVPAAATTVSSP 442
                       + PP+ PT P +      + P  +TT S P
Sbjct: 4239 STLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP 4279



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 97/461 (21%), Positives = 146/461 (31%), Gaps = 58/461 (12%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 3872 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3930

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT    + P+  +    P   PT  Q P 
Sbjct: 3931 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3990

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEH 191
                    T+       G +  T   ++   +  PTP P G  T T TP     +  P  
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050

Query: 192  SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            +P    T  +  +  +T VT        + P   P+  + +       +G       QT 
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTP 4104

Query: 252  ETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS-- 304
             TT I +   +   P+PT     T + +  +T   PT +   +Q   TT I     ++  
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4164

Query: 305  -----SPREDTIPIPSLTSCTETSDPL------PTNENDDDICKKPCSVAPNDI------ 347
                 +    T PI + T+ T T  P       PT+ +   I +   S  P +       
Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224

Query: 348  -----PLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECI 402
                 PL  ST L++ +    E  S              P T       +PP        
Sbjct: 4225 RSTSSPLTESTTLLSTLPPAIEMTSTAPP-----STPTAPTTTSGGHTLSPPPSTTTSPP 4279

Query: 403  PAPI-----------TPSTVPSFPPTPPTPPASPPHTPVIV 432
              P            TPSTV +   +  TP  +P  TP I+
Sbjct: 4280 GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSII 4320



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 54/207 (26%), Positives = 81/207 (39%), Gaps = 31/207 (14%)

Query: 250  TSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSA-LSSQPIFTTAIDDRCELSSPRE 308
            T+  + + +   + LP +PTT ++   +T   PTSS  LS+ P       D      P  
Sbjct: 1259 TTRPSTLTTFTTITLPTTPTTFTTTTTTT--TPTSSTVLSTTPKLCCLWSDWINEDHP-- 1314

Query: 309  DTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSA 368
                    +S ++  D     E  D +C      AP DI   S  +    +  + +K+  
Sbjct: 1315 --------SSGSDDGD----RETFDGVCG-----APEDIECRSVKDPHLSLEQLGQKVQC 1357

Query: 369  TESIVEIVKQE------VLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT-- 420
              S+  I K E         L  + +I  N    M  +CI  P  P+T PS PPT  T  
Sbjct: 1358 DVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMD-KCITTPSPPTTTPSPPPTSTTTL 1416

Query: 421  PPASPPHTPVIVPAAATTVSSPSAAIT 447
            PP + P  P          ++PS  IT
Sbjct: 1417 PPTTTPSPPTTTTTTPPPTTTPSPPIT 1443



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 21/198 (10%)

Query: 250  TSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPRED 309
            T  TT   +  E P PP+ T +++   +T   PT +   +Q   TT              
Sbjct: 1880 TQPTTMTTTTTENPTPPTTTPITT---TTTVTPTPTPTGTQTPTTT-------------- 1922

Query: 310  TIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSAT 369
              PI + T+ T T  P  T            +V P   P  + T     I   +  ++ T
Sbjct: 1923 --PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPT 1979

Query: 370  ESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTP 429
             +          P+T    +   P           PIT +T  +  PT PT   +P  TP
Sbjct: 1980 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP 2038

Query: 430  VIVPAAATTVSSPSAAIT 447
            +      T   +P+   T
Sbjct: 2039 ITTTTTVTPTPTPTGTQT 2056



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 80/380 (21%), Positives = 110/380 (28%), Gaps = 46/380 (12%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q        +   
Sbjct: 4102 QTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQS-APIIVPTQQQPPPAK 136
                P     Q P   P          P   GT   P  P + S API   T   PPP  
Sbjct: 4161 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP--PTHTSTAPIAELTTSNPPPES 4218

Query: 137  REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPT---STPTPPQQLPSQVPEHSP 193
               +T                      SR+ + P+   T   ST  P  ++ S  P  +P
Sbjct: 4219 STPQT----------------------SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256

Query: 194  VVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSET 253
                T    H  +  P T  S      +        +P+P      +            T
Sbjct: 4257 TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST 4316

Query: 254  TAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPI 313
             +I+    L   PS   +  V   T  AP       + ++     D C   +        
Sbjct: 4317 PSIIRTTGLRPYPSSVLICCVLNDTYYAP------GEEVYNGTYGDTCYFVNCSLSCTLE 4370

Query: 314  PSLTSCTETSDPLPTNENDDDICKKPCS--------VAPNDIPLVSSTNLINEINGVSEK 365
                SC  T  P PT         KP S          P + P        NE   + + 
Sbjct: 4371 FYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDC 4430

Query: 366  LSAT---ESIVEIVKQEVLP 382
              AT    + VEIVK E  P
Sbjct: 4431 FMATCKYNNTVEIVKVECEP 4450



 Score = 38.5 bits (88), Expect = 0.052
 Identities = 41/192 (21%), Positives = 68/192 (35%), Gaps = 47/192 (24%)

Query: 263  PLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTET 322
            P PP PT+ +++  +T  +P ++  ++ P  TT        ++P   T P P ++  T T
Sbjct: 1406 PSPP-PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS--TTT 1462

Query: 323  SDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLP 382
            + P  T  +       P +  P+     ++T                             
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP---------------------------- 1494

Query: 383  LTLELEILENPPEEMKLECIPAPITP--STVPSFPPTPPTPPA----SPPHTPVIVPAAA 436
                      PP          PITP  ST    P T P+PP     +PP T    P   
Sbjct: 1495 ----------PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544

Query: 437  TTVSSPSAAITV 448
            T ++ P++  T+
Sbjct: 1545 TPITPPTSTTTL 1556


>gi|169212085 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 516

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 59/248 (23%), Positives = 113/248 (45%), Gaps = 53/248 (21%)

Query: 758 VRSILNKLTPQM------FNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAYAN 811
           V+  LN LT Q         Q  + ++G  V T++ L+ + +L++++A   P+FS   A 
Sbjct: 199 VQDFLNHLTEQPGSFETEIEQFAETLNGC-VTTDDALQELAELIYQQATSIPNFSYMGAR 257

Query: 812 MCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEER 871
           +C  L +  + ++ + GN   FR+LLL RC+ E+E                         
Sbjct: 258 LCNYL-SHHLTISPQSGN---FRQLLLQRCRTEYE------------------------- 288

Query: 872 TRLHDELEEAKDKARRRSIGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLK 919
             + D+  +  +  R+R    + F+GEL+  L++           + +  + + +  L  
Sbjct: 289 --VKDQAAKGDEVTRKRFHAFVFFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFS 346

Query: 920 NHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDV 976
           N  +++L C  +LL   G  L+    EK K  M++   ++E +V +   S  ++ ML  +
Sbjct: 347 NPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKL 406

Query: 977 IDLRLCNW 984
           ++LR  NW
Sbjct: 407 VELRSSNW 414


>gi|239752553 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 457

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 59/248 (23%), Positives = 113/248 (45%), Gaps = 53/248 (21%)

Query: 758 VRSILNKLTPQM------FNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAYAN 811
           V+  LN LT Q         Q  + ++G  V T++ L+ + +L++++A   P+FS   A 
Sbjct: 140 VQDFLNHLTEQPGSFETEIEQFAETLNGC-VTTDDALQELAELIYQQATSIPNFSYMGAR 198

Query: 812 MCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEER 871
           +C  L +  + ++ + GN   FR+LLL RC+ E+E                         
Sbjct: 199 LCNYL-SHHLTISPQSGN---FRQLLLQRCRTEYE------------------------- 229

Query: 872 TRLHDELEEAKDKARRRSIGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLK 919
             + D+  +  +  R+R    + F+GEL+  L++           + +  + + +  L  
Sbjct: 230 --VKDQAAKGDEVTRKRFHAFVFFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFS 287

Query: 920 NHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDV 976
           N  +++L C  +LL   G  L+    EK K  M++   ++E +V +   S  ++ ML  +
Sbjct: 288 NPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKL 347

Query: 977 IDLRLCNW 984
           ++LR  NW
Sbjct: 348 VELRSSNW 355


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 81/361 (22%), Positives = 124/361 (34%), Gaps = 25/361 (6%)

Query: 97   PGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAK--REKKTIRIRDPNQGGKDI 154
            P P P    +   TP   +  V    P   PT  Q P         T+       G +  
Sbjct: 1324 PTPTPTSTQSTTPTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1380

Query: 155  TEEIMSGGGSRNPTP-PIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAA 213
            T   ++   +  PTP P G  T T TP     +  P  +P    T  +  +  +T VT  
Sbjct: 1381 TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1440

Query: 214  SDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPT---- 269
                  + P P  +  + +       +G       QT  TT I +   +   P+PT    
Sbjct: 1441 PTPTGTQAPTPTAITTTSTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQT 1494

Query: 270  -TVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS---SPREDTIPIPSLTSCTETSDP 325
             T +++  +T   PT +   +Q   +T I     ++   +P     P P+  S T T  P
Sbjct: 1495 PTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP 1554

Query: 326  LPTNENDDDICKKPCS----VAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVL 381
             PT          P +    V P   P  + T     I   +  ++ T +        V 
Sbjct: 1555 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLIT-TTTTMTPTPTPTSTKSTTVT 1613

Query: 382  PLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSS 441
            P+T    +   P           PI+ +T  +  PTP T    PP      P A  T S+
Sbjct: 1614 PITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSN 1673

Query: 442  P 442
            P
Sbjct: 1674 P 1674



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 104/453 (22%), Positives = 148/453 (32%), Gaps = 55/453 (12%)

Query: 7    TRSPFFQRPQIQPPRATIPNSSPSIRP-GAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQ 65
            T +P   +     P  T    +P+  P G QTPT         +       P P P G Q
Sbjct: 1325 TPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTP------ITTTTTVTPTPTPTGTQ 1378

Query: 66   YCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA--- 122
                    +       P     Q P   P          P   GT    + P+  +    
Sbjct: 1379 TPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1438

Query: 123  --PIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-PIGRPTSTPT 179
              P    TQ   P A     T+       G +  T   ++   +  PTP P G  T TPT
Sbjct: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPT 1498

Query: 180  PPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVL 239
                  +  P  +P    T  S  +  +T VT        + P P P+  + +       
Sbjct: 1499 AITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTP 1558

Query: 240  SGEKKEQEGQTSETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQ---- 290
            +G       QT  TT I +   +   P+PT     T   +  +T   PT +  S++    
Sbjct: 1559 TGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTV 1612

Query: 291  -PIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPL 349
             PI TT         +  +    IP  T+ T T  P PT            S  P   P 
Sbjct: 1613 TPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTG----------STGP---PT 1659

Query: 350  VSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPS 409
             +ST  I E+   +       S  +  +    PLT    +L   P        PA    S
Sbjct: 1660 HTSTAPIAELT--TSNPPPESSTPQTSRSTSSPLTESTTLLSTLP--------PAIEMTS 1709

Query: 410  TVPSFPPTPPTPPASPPHTPVIVPAAATTVSSP 442
            T P   P+ PT P +      + P  +TT S P
Sbjct: 1710 TAP---PSTPTAPTTTSGGHTLSPPPSTTTSPP 1739



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 64/289 (22%), Positives = 100/289 (34%), Gaps = 22/289 (7%)

Query: 177  TPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLR 236
            TPTP     +  P  +P    +     +  +T VT        + P   P+  + +    
Sbjct: 1312 TPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1371

Query: 237  LVLSGEKKEQEGQTSETTAIVSIAELPLPPSPT-----TVSSVARSTIAAPTSSALSSQP 291
               +G       QT  TT I +   +   P+PT     T + +  +T   PT +   +Q 
Sbjct: 1372 PTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT 1425

Query: 292  IFTTAIDDRCELS---SPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCS----VAP 344
              TT I     ++   +P     P P+  + T T  P PT          P +    V P
Sbjct: 1426 PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTP 1485

Query: 345  NDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPA 404
               P  + T     I   +  ++ T +          P+T    +   P         P 
Sbjct: 1486 TPTPTGTQTPTPTAIT-TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPT 1544

Query: 405  PITPSTVPSFPPTP-PTPPASPPHTPVIVPAAATTVSSPSAAITVQRVL 452
            PI  ST  +  PTP PT   +P  TP+      T   +P+   T   VL
Sbjct: 1545 PI--STTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL 1591



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 65/296 (21%), Positives = 106/296 (35%), Gaps = 25/296 (8%)

Query: 167  PTP-PIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPD 225
            PTP P G  T T TP     +  P  +P    T  +  +  +T VT        + P   
Sbjct: 1347 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST 1406

Query: 226  PVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPT-----TVSSVARSTIA 280
            P+  + +       +G       QT  TT I +   +   P+PT     T +++  ++  
Sbjct: 1407 PITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTV 1460

Query: 281  APTSSALSSQPIFTTAIDDRCELS---SPREDTIPIPSLTSCTETSDPLPTNENDDDICK 337
             PT +   +Q   TT I     ++   +P     P P+  + T T  P PT         
Sbjct: 1461 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTS 1520

Query: 338  KP----CSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENP 393
             P     +V P   P  + T     I+  +  ++ T +          P+T    +   P
Sbjct: 1521 TPITTTTTVTPTPTPTGTQTPTPTPIS-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579

Query: 394  -PEEMKLECIPAPITPSTVPSFPPTP-PTPPASPPHTPVIVPAAATTVSSPSAAIT 447
             P   +    P  +  +T  +  PTP PT   S   TP+      T   +P+   T
Sbjct: 1580 TPTGTQ---TPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQT 1632



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 93/440 (21%), Positives = 137/440 (31%), Gaps = 33/440 (7%)

Query: 18   QPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPP 77
            Q P  T   ++ ++ P   TPT         +       P P P G Q   P    +   
Sbjct: 1447 QAPTPTAITTTSTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTT 1505

Query: 78   YVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA---PIIVPTQQQPPP 134
                P     Q P   P          P   GT      P+  +    P   PT  Q P 
Sbjct: 1506 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPT 1565

Query: 135  AK--REKKTIRIRDPNQGGKDITEEIMSGGGSRNPTP-----------PIGRPTS---TP 178
                    T+       G +  T  +++   +  PTP           PI   T+   TP
Sbjct: 1566 TTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATP 1625

Query: 179  TPP-QQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRL 237
            TP   Q P+ +P  +        +    ++ P T  S     E    +P  +S +P    
Sbjct: 1626 TPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 1685

Query: 238  VLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAI 297
              S    E     S     + +     P +PT  ++ +     +P  S  +S P   T  
Sbjct: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG 1745

Query: 298  DDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLIN 357
                  S+P   T+   + ++ T T  PL T         +P    P+ + +    N   
Sbjct: 1746 TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP---YPSSVLICCVLNDTY 1802

Query: 358  EINGVSEKLSATESIVEIVKQEVLPLTLELEILENP----PEEMKLECIPAPITPSTVPS 413
               G  E  + T           L  TLE      P    P     +  P P  PS+ PS
Sbjct: 1803 YAPG-EEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPS 1861

Query: 414  FPPTPPTPPASPPHTPVIVP 433
                 PTP   PP  P   P
Sbjct: 1862 ----KPTPGTKPPECPDFDP 1877



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 38/170 (22%), Positives = 56/170 (32%), Gaps = 16/170 (9%)

Query: 277  STIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDIC 336
            +T+   T+   +  PI TT         +  + T P P  T+ T T  P PT        
Sbjct: 1301 TTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG------- 1353

Query: 337  KKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEE 396
                +  P   P+ ++T +         +   T  I         P     +   + P  
Sbjct: 1354 ----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409

Query: 397  MKLECIPAPI-----TPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSS 441
                  P P      TP+T P    T  TP  +P  T    P A TT S+
Sbjct: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST 1459



 Score = 40.4 bits (93), Expect = 0.014
 Identities = 84/393 (21%), Positives = 115/393 (29%), Gaps = 54/393 (13%)

Query: 7    TRSPFFQRPQIQPPRATIPNSSPSIRP-GAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQ 65
            T +P   +     P  T    +P+  P G QTPT V       M     P P P      
Sbjct: 1555 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMT----PTPTPTSTKST 1610

Query: 66   YCIPQYRHSGPPYVGPPQ--QYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAP 123
               P    +       P   Q P   P        P P     + G P + S     +AP
Sbjct: 1611 TVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS-----TAP 1665

Query: 124  IIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPT---STPTP 180
            I   T   PPP     +T                      SR+ + P+   T   ST  P
Sbjct: 1666 IAELTTSNPPPESSTPQT----------------------SRSTSSPLTESTTLLSTLPP 1703

Query: 181  PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS 240
              ++ S  P  +P    T    H  +  P T  S      +        +P+P      +
Sbjct: 1704 AIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 1763

Query: 241  GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR 300
                        T +I+    L   PS   +  V   T  AP       + ++     D 
Sbjct: 1764 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP------GEEVYNGTYGDT 1817

Query: 301  CELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCS--------VAPNDIPLVSS 352
            C   +            SC  T  P PT         KP S          P + P    
Sbjct: 1818 CYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDP 1877

Query: 353  TNLINEINGVSEKLSAT---ESIVEIVKQEVLP 382
                NE   + +   AT    + VEIVK E  P
Sbjct: 1878 PRQENETWWLCDCFMATCKYNNTVEIVKVECEP 1910



 Score = 38.5 bits (88), Expect = 0.052
 Identities = 55/233 (23%), Positives = 77/233 (33%), Gaps = 52/233 (22%)

Query: 250  TSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSA-LSSQPIFTTAIDDRCELSSPR- 307
            T+  + + +   + LP +PTT ++   +T   PTSS  LS+ P       D      P  
Sbjct: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTT--TPTSSTVLSTTPKLCCLWSDWINEDHPSS 1217

Query: 308  ----------EDTIPIPSLTSCTETSDP------------LPTNENDDDICKKPCSVAPN 345
                      +     P    C    DP            L  + +   ICK        
Sbjct: 1218 GSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGG 1277

Query: 346  DIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENP---PEEMKLECI 402
             IP+    N   EIN            V+  +    P T+     ENP   P        
Sbjct: 1278 VIPMAFCLNY--EIN------------VQCCECVTQPTTMTTTTTENPTPTPITTTTTVT 1323

Query: 403  PAPITPSTVPSFPPTP--------PTPPASPPHTPVIVPAAATTVSSPSAAIT 447
            P P TP++  S  PTP        PTP  +   TP   P   TT  +P+   T
Sbjct: 1324 PTP-TPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1375


>gi|89041275 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 488

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 59/248 (23%), Positives = 113/248 (45%), Gaps = 53/248 (21%)

Query: 758 VRSILNKLTPQM------FNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAYAN 811
           V+  LN LT Q         Q  + ++G  V T++ L+ + +L++++A   P+FS   A 
Sbjct: 171 VQDFLNHLTEQPGSFETEIEQFAETLNGC-VTTDDALQELAELIYQQATSIPNFSYMGAR 229

Query: 812 MCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEER 871
           +C  L +  + ++ + GN   FR+LLL RC+ E+E                         
Sbjct: 230 LCNYL-SHHLTISPQSGN---FRQLLLQRCRTEYE------------------------- 260

Query: 872 TRLHDELEEAKDKARRRSIGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLK 919
             + D+  +  +  R+R    + F+GEL+  L++           + +  + + +  L  
Sbjct: 261 --VKDQAAKGDEVTRKRFHAFVFFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFS 318

Query: 920 NHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDV 976
           N  +++L C  +LL   G  L+    EK K  M++   ++E +V +   S  ++ ML  +
Sbjct: 319 NPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKL 378

Query: 977 IDLRLCNW 984
           ++LR  NW
Sbjct: 379 VELRSSNW 386


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 101/449 (22%), Positives = 146/449 (32%), Gaps = 51/449 (11%)

Query: 75  GPPYVGPPQQYPVQPPGPGPFYPG-PGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPP 133
           GP    P +  P  P  P    P  P P    +A  TP  P+    +SAP   P +  P 
Sbjct: 207 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPT 265

Query: 134 PAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSP 193
             K    T     P +     T+E         PT P  +  +  TP +  P+   E +P
Sbjct: 266 TTKEPAPTT----PKEPAPTTTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAP 319

Query: 194 VVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSET 253
                         TP T        ++P P    K P+P      +  KK      + T
Sbjct: 320 TTP--------KEPTPTTPKEPAPTTKEPAPTTP-KEPAP------TAPKKP-----APT 359

Query: 254 TAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPI 313
           T        P  P+PTT    + +T   P  +   S P  T         S+P     P 
Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 419

Query: 314 PSLT---SCTETSDPLPTNENDD--DICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSA 368
           P+ T   + T   +P PT          K+P    P + P  ++T             + 
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPAPTT 478

Query: 369 TESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHT 428
            +       +++ P T E ++    PE+      PAP TP  +    P  PTP       
Sbjct: 479 PKETAPTTPKKLTPTTPE-KLAPTTPEK------PAPTTPEELAPTTPEEPTPTTPEEPA 531

Query: 429 PVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEI-QNKIEVEADGQTEEILDS 487
           P    AAA       A  T +      E   T   E A    +        G     L  
Sbjct: 532 PTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585

Query: 488 QNLNSRRSPVPAQIAITVPKTWKKPKDRT 516
               + + P P ++A   P T K+P   T
Sbjct: 586 PAPTTPKKPAPKELA---PTTTKEPTSTT 611



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 129/570 (22%), Positives = 187/570 (32%), Gaps = 104/570 (18%)

Query: 4   QPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPY----P 59
           +P   +P    P  + P  T P       P    PT      +        P P     P
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT---PKEPAPTTPKEPAPTTTKEP 380

Query: 60  VPQGPQYCIPQYRHSGPPYVGPP-----QQYPVQPPGPGPFY---PGPGPGDFPNAYGTP 111
            P  P+   P    S P     P     +  P  P  P P     P P     P     P
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----AP 436

Query: 112 FYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI 171
             P +P   +     PT  + P     KK               E   +      PT P 
Sbjct: 437 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 496

Query: 172 GRPTSTP-----TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKP---- 222
               +TP     T P++L    PE       T E    A +TP  AA +  +E  P    
Sbjct: 497 KLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEP--APTTPKAAAPNTPKEPAPTTPK 552

Query: 223 KPDPVL-KSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAE-LPLPPSPTTVSSVARSTIA 280
           +P P   K P+P          KE    T + TA  ++ E  P  P       +A +T  
Sbjct: 553 EPAPTTPKEPAPTT-------PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 605

Query: 281 APTSSALSSQPIFTT------AIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDD 334
            PTS+    +P  TT              ++P+E     P  T+ T   +P PT      
Sbjct: 606 EPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---- 660

Query: 335 ICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPP 394
             KKP   AP ++   + T      +  S+K + T        +E  P T         P
Sbjct: 661 --KKP---APKEL---APTTTKGPTSTTSDKPAPT------TPKETAPTT---------P 697

Query: 395 EEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEE 454
           +E      PAP TP       P P TP   PP T        + VS+P+         +E
Sbjct: 698 KE------PAPTTPK-----KPAPTTPETPPPTT--------SEVSTPTTT-------KE 731

Query: 455 DESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKD 514
             +I     E   E+  +   +A    E       + + ++P   +  +T     K  + 
Sbjct: 732 PTTIHKSPDESTPELSAEPTPKA---LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788

Query: 515 RTRTTEEMLEAELELKAEEELSIDKVLESE 544
             RTT E   A  ++  E   + +K  ES+
Sbjct: 789 DLRTTPETTTAAPKMTKETATTTEKTTESK 818



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 75/320 (23%), Positives = 100/320 (31%), Gaps = 41/320 (12%)

Query: 201 SAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIA 260
           SA    S   T+A D     K     VL  P+P       G       + + TT     +
Sbjct: 172 SAKETQSIEKTSAKDLAPTSK-----VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 226

Query: 261 ELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCT 320
             P  P+PTT+ S A +T   P  +   S P            ++P+E   P P     T
Sbjct: 227 TTPKEPTPTTIKS-APTTPKEPAPTTTKSAP------------TTPKE---PAP-----T 265

Query: 321 ETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSAT-ESIVEIVKQE 379
            T +P PT          P   AP      + T   +      E    T +       +E
Sbjct: 266 TTKEPAPTT---------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316

Query: 380 VLPLTLELEILENPPEEMKLECIPAPITP-STVPSFP--PTPPTPPASPPHTPVIVPAAA 436
             P T +      P E       PAP TP    P+ P  P P TP    P TP     A 
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAP 374

Query: 437 TTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP 496
           TT   PS     +      +S  T   E A              +          + + P
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434

Query: 497 VPAQIAITVPKTWKKPKDRT 516
            P       P T K+P   T
Sbjct: 435 APTTPKKPAPTTPKEPAPTT 454


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 101/449 (22%), Positives = 146/449 (32%), Gaps = 51/449 (11%)

Query: 75  GPPYVGPPQQYPVQPPGPGPFYPG-PGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPP 133
           GP    P +  P  P  P    P  P P    +A  TP  P+    +SAP   P +  P 
Sbjct: 248 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPT 306

Query: 134 PAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSP 193
             K    T     P +     T+E         PT P  +  +  TP +  P+   E +P
Sbjct: 307 TTKEPAPTT----PKEPAPTTTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAP 360

Query: 194 VVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSET 253
                         TP T        ++P P    K P+P      +  KK      + T
Sbjct: 361 TTP--------KEPTPTTPKEPAPTTKEPAPTTP-KEPAP------TAPKKP-----APT 400

Query: 254 TAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPI 313
           T        P  P+PTT    + +T   P  +   S P  T         S+P     P 
Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 460

Query: 314 PSLT---SCTETSDPLPTNENDD--DICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSA 368
           P+ T   + T   +P PT          K+P    P + P  ++T             + 
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPAPTT 519

Query: 369 TESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHT 428
            +       +++ P T E ++    PE+      PAP TP  +    P  PTP       
Sbjct: 520 PKETAPTTPKKLTPTTPE-KLAPTTPEK------PAPTTPEELAPTTPEEPTPTTPEEPA 572

Query: 429 PVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEI-QNKIEVEADGQTEEILDS 487
           P    AAA       A  T +      E   T   E A    +        G     L  
Sbjct: 573 PTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626

Query: 488 QNLNSRRSPVPAQIAITVPKTWKKPKDRT 516
               + + P P ++A   P T K+P   T
Sbjct: 627 PAPTTPKKPAPKELA---PTTTKEPTSTT 652



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 129/570 (22%), Positives = 187/570 (32%), Gaps = 104/570 (18%)

Query: 4   QPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPY----P 59
           +P   +P    P  + P  T P       P    PT      +        P P     P
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT---PKEPAPTTPKEPAPTTTKEP 421

Query: 60  VPQGPQYCIPQYRHSGPPYVGPP-----QQYPVQPPGPGPFY---PGPGPGDFPNAYGTP 111
            P  P+   P    S P     P     +  P  P  P P     P P     P     P
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----AP 477

Query: 112 FYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI 171
             P +P   +     PT  + P     KK               E   +      PT P 
Sbjct: 478 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 537

Query: 172 GRPTSTP-----TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKP---- 222
               +TP     T P++L    PE       T E    A +TP  AA +  +E  P    
Sbjct: 538 KLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEP--APTTPKAAAPNTPKEPAPTTPK 593

Query: 223 KPDPVL-KSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAE-LPLPPSPTTVSSVARSTIA 280
           +P P   K P+P          KE    T + TA  ++ E  P  P       +A +T  
Sbjct: 594 EPAPTTPKEPAPTT-------PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 646

Query: 281 APTSSALSSQPIFTT------AIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDD 334
            PTS+    +P  TT              ++P+E     P  T+ T   +P PT      
Sbjct: 647 EPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---- 701

Query: 335 ICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPP 394
             KKP   AP ++   + T      +  S+K + T        +E  P T         P
Sbjct: 702 --KKP---APKEL---APTTTKGPTSTTSDKPAPT------TPKETAPTT---------P 738

Query: 395 EEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEE 454
           +E      PAP TP       P P TP   PP T        + VS+P+         +E
Sbjct: 739 KE------PAPTTPK-----KPAPTTPETPPPTT--------SEVSTPTTT-------KE 772

Query: 455 DESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKD 514
             +I     E   E+  +   +A    E       + + ++P   +  +T     K  + 
Sbjct: 773 PTTIHKSPDESTPELSAEPTPKA---LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829

Query: 515 RTRTTEEMLEAELELKAEEELSIDKVLESE 544
             RTT E   A  ++  E   + +K  ES+
Sbjct: 830 DLRTTPETTTAAPKMTKETATTTEKTTESK 859



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 75/320 (23%), Positives = 100/320 (31%), Gaps = 41/320 (12%)

Query: 201 SAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIA 260
           SA    S   T+A D     K     VL  P+P       G       + + TT     +
Sbjct: 213 SAKETQSIEKTSAKDLAPTSK-----VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 267

Query: 261 ELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCT 320
             P  P+PTT+ S A +T   P  +   S P            ++P+E   P P     T
Sbjct: 268 TTPKEPTPTTIKS-APTTPKEPAPTTTKSAP------------TTPKE---PAP-----T 306

Query: 321 ETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSAT-ESIVEIVKQE 379
            T +P PT          P   AP      + T   +      E    T +       +E
Sbjct: 307 TTKEPAPTT---------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357

Query: 380 VLPLTLELEILENPPEEMKLECIPAPITP-STVPSFP--PTPPTPPASPPHTPVIVPAAA 436
             P T +      P E       PAP TP    P+ P  P P TP    P TP     A 
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAP 415

Query: 437 TTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP 496
           TT   PS     +      +S  T   E A              +          + + P
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475

Query: 497 VPAQIAITVPKTWKKPKDRT 516
            P       P T K+P   T
Sbjct: 476 APTTPKKPAPTTPKEPAPTT 495


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 101/449 (22%), Positives = 146/449 (32%), Gaps = 51/449 (11%)

Query: 75  GPPYVGPPQQYPVQPPGPGPFYPG-PGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPP 133
           GP    P +  P  P  P    P  P P    +A  TP  P+    +SAP   P +  P 
Sbjct: 300 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPT 358

Query: 134 PAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSP 193
             K    T     P +     T+E         PT P  +  +  TP +  P+   E +P
Sbjct: 359 TTKEPAPTT----PKEPAPTTTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAP 412

Query: 194 VVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSET 253
                         TP T        ++P P    K P+P      +  KK      + T
Sbjct: 413 TTP--------KEPTPTTPKEPAPTTKEPAPTTP-KEPAP------TAPKKP-----APT 452

Query: 254 TAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPI 313
           T        P  P+PTT    + +T   P  +   S P  T         S+P     P 
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 512

Query: 314 PSLT---SCTETSDPLPTNENDD--DICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSA 368
           P+ T   + T   +P PT          K+P    P + P  ++T             + 
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPAPTT 571

Query: 369 TESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHT 428
            +       +++ P T E ++    PE+      PAP TP  +    P  PTP       
Sbjct: 572 PKETAPTTPKKLTPTTPE-KLAPTTPEK------PAPTTPEELAPTTPEEPTPTTPEEPA 624

Query: 429 PVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEI-QNKIEVEADGQTEEILDS 487
           P    AAA       A  T +      E   T   E A    +        G     L  
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 678

Query: 488 QNLNSRRSPVPAQIAITVPKTWKKPKDRT 516
               + + P P ++A   P T K+P   T
Sbjct: 679 PAPTTPKKPAPKELA---PTTTKEPTSTT 704



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 129/570 (22%), Positives = 187/570 (32%), Gaps = 104/570 (18%)

Query: 4   QPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPY----P 59
           +P   +P    P  + P  T P       P    PT      +        P P     P
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT---PKEPAPTTPKEPAPTTTKEP 473

Query: 60  VPQGPQYCIPQYRHSGPPYVGPP-----QQYPVQPPGPGPFY---PGPGPGDFPNAYGTP 111
            P  P+   P    S P     P     +  P  P  P P     P P     P     P
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----AP 529

Query: 112 FYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI 171
             P +P   +     PT  + P     KK               E   +      PT P 
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 589

Query: 172 GRPTSTP-----TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKP---- 222
               +TP     T P++L    PE       T E    A +TP  AA +  +E  P    
Sbjct: 590 KLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEP--APTTPKAAAPNTPKEPAPTTPK 645

Query: 223 KPDPVL-KSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAE-LPLPPSPTTVSSVARSTIA 280
           +P P   K P+P          KE    T + TA  ++ E  P  P       +A +T  
Sbjct: 646 EPAPTTPKEPAPTT-------PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 698

Query: 281 APTSSALSSQPIFTT------AIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDD 334
            PTS+    +P  TT              ++P+E     P  T+ T   +P PT      
Sbjct: 699 EPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---- 753

Query: 335 ICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPP 394
             KKP   AP ++   + T      +  S+K + T        +E  P T         P
Sbjct: 754 --KKP---APKEL---APTTTKGPTSTTSDKPAPT------TPKETAPTT---------P 790

Query: 395 EEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEE 454
           +E      PAP TP       P P TP   PP T        + VS+P+         +E
Sbjct: 791 KE------PAPTTPK-----KPAPTTPETPPPTT--------SEVSTPTTT-------KE 824

Query: 455 DESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKD 514
             +I     E   E+  +   +A    E       + + ++P   +  +T     K  + 
Sbjct: 825 PTTIHKSPDESTPELSAEPTPKA---LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881

Query: 515 RTRTTEEMLEAELELKAEEELSIDKVLESE 544
             RTT E   A  ++  E   + +K  ES+
Sbjct: 882 DLRTTPETTTAAPKMTKETATTTEKTTESK 911



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 75/320 (23%), Positives = 100/320 (31%), Gaps = 41/320 (12%)

Query: 201 SAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIA 260
           SA    S   T+A D     K     VL  P+P       G       + + TT     +
Sbjct: 265 SAKETQSIEKTSAKDLAPTSK-----VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 319

Query: 261 ELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCT 320
             P  P+PTT+ S A +T   P  +   S P            ++P+E   P P     T
Sbjct: 320 TTPKEPTPTTIKS-APTTPKEPAPTTTKSAP------------TTPKE---PAP-----T 358

Query: 321 ETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSAT-ESIVEIVKQE 379
            T +P PT          P   AP      + T   +      E    T +       +E
Sbjct: 359 TTKEPAPTT---------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409

Query: 380 VLPLTLELEILENPPEEMKLECIPAPITP-STVPSFP--PTPPTPPASPPHTPVIVPAAA 436
             P T +      P E       PAP TP    P+ P  P P TP    P TP     A 
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAP 467

Query: 437 TTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP 496
           TT   PS     +      +S  T   E A              +          + + P
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527

Query: 497 VPAQIAITVPKTWKKPKDRT 516
            P       P T K+P   T
Sbjct: 528 APTTPKKPAPTTPKEPAPTT 547


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 101/449 (22%), Positives = 146/449 (32%), Gaps = 51/449 (11%)

Query: 75  GPPYVGPPQQYPVQPPGPGPFYPG-PGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPP 133
           GP    P +  P  P  P    P  P P    +A  TP  P+    +SAP   P +  P 
Sbjct: 341 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPT 399

Query: 134 PAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSP 193
             K    T     P +     T+E         PT P  +  +  TP +  P+   E +P
Sbjct: 400 TTKEPAPTT----PKEPAPTTTKEPAPTTTKSAPTTP--KEPAPTTPKKPAPTTPKEPAP 453

Query: 194 VVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSET 253
                         TP T        ++P P    K P+P      +  KK      + T
Sbjct: 454 TTP--------KEPTPTTPKEPAPTTKEPAPTTP-KEPAP------TAPKKP-----APT 493

Query: 254 TAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPI 313
           T        P  P+PTT    + +T   P  +   S P  T         S+P     P 
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 553

Query: 314 PSLT---SCTETSDPLPTNENDD--DICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSA 368
           P+ T   + T   +P PT          K+P    P + P  ++T             + 
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PAPTTTKKPAPTTPKEPAPTT 612

Query: 369 TESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHT 428
            +       +++ P T E ++    PE+      PAP TP  +    P  PTP       
Sbjct: 613 PKETAPTTPKKLTPTTPE-KLAPTTPEK------PAPTTPEELAPTTPEEPTPTTPEEPA 665

Query: 429 PVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEI-QNKIEVEADGQTEEILDS 487
           P    AAA       A  T +      E   T   E A    +        G     L  
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719

Query: 488 QNLNSRRSPVPAQIAITVPKTWKKPKDRT 516
               + + P P ++A   P T K+P   T
Sbjct: 720 PAPTTPKKPAPKELA---PTTTKEPTSTT 745



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 129/570 (22%), Positives = 187/570 (32%), Gaps = 104/570 (18%)

Query: 4   QPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPY----P 59
           +P   +P    P  + P  T P       P    PT      +        P P     P
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT---PKEPAPTTPKEPAPTTTKEP 514

Query: 60  VPQGPQYCIPQYRHSGPPYVGPP-----QQYPVQPPGPGPFY---PGPGPGDFPNAYGTP 111
            P  P+   P    S P     P     +  P  P  P P     P P     P     P
Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----AP 570

Query: 112 FYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI 171
             P +P   +     PT  + P     KK               E   +      PT P 
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 630

Query: 172 GRPTSTP-----TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKP---- 222
               +TP     T P++L    PE       T E    A +TP  AA +  +E  P    
Sbjct: 631 KLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEP--APTTPKAAAPNTPKEPAPTTPK 686

Query: 223 KPDPVL-KSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAE-LPLPPSPTTVSSVARSTIA 280
           +P P   K P+P          KE    T + TA  ++ E  P  P       +A +T  
Sbjct: 687 EPAPTTPKEPAPTT-------PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 739

Query: 281 APTSSALSSQPIFTT------AIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDD 334
            PTS+    +P  TT              ++P+E     P  T+ T   +P PT      
Sbjct: 740 EPTSTTCD-KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP---- 794

Query: 335 ICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPP 394
             KKP   AP ++   + T      +  S+K + T        +E  P T         P
Sbjct: 795 --KKP---APKEL---APTTTKGPTSTTSDKPAPT------TPKETAPTT---------P 831

Query: 395 EEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEE 454
           +E      PAP TP       P P TP   PP T        + VS+P+         +E
Sbjct: 832 KE------PAPTTPK-----KPAPTTPETPPPTT--------SEVSTPTTT-------KE 865

Query: 455 DESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKD 514
             +I     E   E+  +   +A    E       + + ++P   +  +T     K  + 
Sbjct: 866 PTTIHKSPDESTPELSAEPTPKA---LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922

Query: 515 RTRTTEEMLEAELELKAEEELSIDKVLESE 544
             RTT E   A  ++  E   + +K  ES+
Sbjct: 923 DLRTTPETTTAAPKMTKETATTTEKTTESK 952



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 75/320 (23%), Positives = 100/320 (31%), Gaps = 41/320 (12%)

Query: 201 SAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIA 260
           SA    S   T+A D     K     VL  P+P       G       + + TT     +
Sbjct: 306 SAKETQSIEKTSAKDLAPTSK-----VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 360

Query: 261 ELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCT 320
             P  P+PTT+ S A +T   P  +   S P            ++P+E   P P     T
Sbjct: 361 TTPKEPTPTTIKS-APTTPKEPAPTTTKSAP------------TTPKE---PAP-----T 399

Query: 321 ETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSAT-ESIVEIVKQE 379
            T +P PT          P   AP      + T   +      E    T +       +E
Sbjct: 400 TTKEPAPTT---------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450

Query: 380 VLPLTLELEILENPPEEMKLECIPAPITP-STVPSFP--PTPPTPPASPPHTPVIVPAAA 436
             P T +      P E       PAP TP    P+ P  P P TP    P TP     A 
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP--KEPAP 508

Query: 437 TTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSP 496
           TT   PS     +      +S  T   E A              +          + + P
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568

Query: 497 VPAQIAITVPKTWKKPKDRT 516
            P       P T K+P   T
Sbjct: 569 APTTPKKPAPTTPKEPAPTT 588


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 93/443 (20%), Positives = 156/443 (35%), Gaps = 54/443 (12%)

Query: 6     QTRSPFFQRPQIQPPRATIPNSSPSIRPGAQT---PTAVYQANQHIMMVNHLPMPYPV-P 61
             + R P  + P++ PP+  +P     + P  +    P  V +A + ++    +P+P P  P
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546

Query: 62    QGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP---- 117
             + P   +P+   +  P    P+  P +P  P P  P       P        P +P    
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606

Query: 118   --VYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPT 175
               V ++   +VP ++ P P  ++ +    + P      + E+ +         PP  +P 
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVP-----EAIPP--KPE 10659

Query: 176   STPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPS--- 232
             S P    + P +V    P     VE    AA   VT    +   EK  P  V K P    
Sbjct: 10660 SPPPEVFEEPEEVALEEPPAE-VVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPP 10718

Query: 233   ----PVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTS-SAL 287
                  V + V+  +K               + E+P    P    +V +     P     +
Sbjct: 10719 VKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV 10778

Query: 288   SSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDI 347
               +P+    ++++  +  P     P P +    E   P      +++   KP  VA  + 
Sbjct: 10779 PKKPV----LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE---KPVPVAEEEE 10831

Query: 348   PLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPIT 407
             P V    +  E      K    E  V ++K+   P          PP+E      P P  
Sbjct: 10832 PEVPPPAVPEE-----PKKIIPEKKVPVIKKPEAP----------PPKE------PEPEK 10870

Query: 408   PSTVPSFPPTPPTPPASPPHTPV 430
                 P   P PP PP +PP   V
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDV 10893



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 137/705 (19%), Positives = 244/705 (34%), Gaps = 123/705 (17%)

Query: 47   HIMMVNHLPMPYPVPQGPQYCIPQYRHSGP--PYVGPPQ-QYPVQPPGPGPFYPGPGPGD 103
            H+ +   +  P  VP+ P+   P+     P    V PP  + P  P  P P    P P  
Sbjct: 9275 HVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVP 9334

Query: 104  FPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGG 163
                   P  P  P        VP ++ P P  ++K+    + P      +TEE ++   
Sbjct: 9335 KKEPAAPPKVPEVPKKP-----VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVT 9389

Query: 164  SRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPK 223
             R  +PP       P  P+    +VPE    V    E        P        +E+   
Sbjct: 9390 QREESPP-------PAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAV 9442

Query: 224  PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVS---IAELPLPPSPTTVSSVARSTIA 280
            P PV K   P               + S+ T +     +AE  L  +      V R  ++
Sbjct: 9443 PVPVAKKAPP------------PRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVS 9490

Query: 281  APTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPC 340
            A    + S +       ++   +S  RE+           E  +       + ++ ++P 
Sbjct: 9491 AEEEWSYSEE-------EEGVSISVYREE-----------EREEEEEAEVTEYEVMEEPE 9532

Query: 341  SVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
                 +   + S  +  E   V+E+        +IV +  +P  +E       PE  K +
Sbjct: 9533 EYVVEEKLHIISKRVEAEPAEVTERQEK-----KIVLKPKIPAKIEEPPPAKVPEAPK-K 9586

Query: 401  CIPAPITPSTVPSFPPTPPTPPASPPHTPV---IVPAAATTVSSPSAAITVQRVLEEDES 457
             +P    P+ VP     PP      P  PV    VP     +  P  A   +R ++  + 
Sbjct: 9587 IVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQE 9646

Query: 458  IRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWK-KPKDRT 516
             +  ++   KE   K  V                    P   + A+   K  K KPK   
Sbjct: 9647 EKVLVAVTKKEAPPKARV--------------------PEEPKRAVPEEKVLKLKPKREE 9686

Query: 517  RTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEP 576
                ++ E    +  EE++SI+               P+R+P  +K+V  +EE  E A  
Sbjct: 9687 EPPAKVTEFRKRVVKEEKVSIEA--------------PKREPQPIKEVTIMEEK-ERAYT 9731

Query: 577  VRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKP-ESWKPTDT-EGKKQYDREFLLDFQF 634
            +   A SV   E  +          +   + +K  E ++PT+  +  ++Y+      ++ 
Sbjct: 9732 LEEEAVSVQREEEYE----------EYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEE 9781

Query: 635  MPACIQKPEGLPPISDVVLDKI-NQPKLPMRTLDPRILPRGPDFTPAFADFGRQTPGGRG 693
                I +PE   P+  V  + +  +PK P   +  + +P              + P    
Sbjct: 9782 HEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPE------------EKVP---- 9825

Query: 694  VPLLNVGSRRSQPGQRREPRKIITVSVKEDVHLKKAENAWKPSQK 738
            VP+     +   P    EP+K+    ++  +  ++ E   +P+ K
Sbjct: 9826 VPIPK-KLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAK 9869



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 89/441 (20%), Positives = 170/441 (38%), Gaps = 57/441 (12%)

Query: 120  QSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPT 179
            +  P  VP ++ PPP K  KK + I    +  + + EE +             + T  P 
Sbjct: 9163 RKVPAKVPEKKAPPPPKVIKKPV-IEKIEKTSRRMEEEKV-------------QVTKVPE 9208

Query: 180  PPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVL 239
              +++  Q P  +PV    +E    A  T     S++K       +  +    P ++  +
Sbjct: 9209 VSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEI 9268

Query: 240  SGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDD 299
              E+K     +        + ELP  P+P  V+ V       P +  +   P      ++
Sbjct: 9269 VTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP-KKPVPEE 9327

Query: 300  RCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINE- 358
            +  +  P+++    P +    +   P+P  +    + KK     P  +P V    +  E 
Sbjct: 9328 KKPVPVPKKEPAAPPKVPEVPK--KPVPEEKIPVPVAKKK-EAPPAKVPEVQKGVVTEEK 9384

Query: 359  INGVSEK-LSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPT 417
            I  V+++  S   ++ EI K++V             PEE K    P P     VP  P  
Sbjct: 9385 ITIVTQREESPPPAVPEIPKKKV-------------PEERK----PVPRKEEEVPPPPKV 9427

Query: 418  PPTPPASPPHTPVIVPA-AATTVSSPSAAITVQRVLEE-----DESIRTCLSEDAKEIQN 471
            P  P    P   V VP   A     P A ++ + V+EE     +E +   + +  +  ++
Sbjct: 9428 PALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRH 9487

Query: 472  KIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTE-EMLEAELELK 530
            ++  E +    E  +  +++  R            +  ++ ++    TE E++E   E  
Sbjct: 9488 EVSAEEEWSYSEEEEGVSISVYR------------EEEREEEEEAEVTEYEVMEEPEEYV 9535

Query: 531  AEEELS-IDKVLESEQDKMSQ 550
             EE+L  I K +E+E  ++++
Sbjct: 9536 VEEKLHIISKRVEAEPAEVTE 9556



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 117/532 (21%), Positives = 190/532 (35%), Gaps = 109/532 (20%)

Query: 82    PQQYPVQPPGPGPF----YPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKR 137
             P + P  P  P P      P P   + P A   P  P +P  +  P+++P +++PPPAK 
Sbjct: 9947  PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAK-VPEVPKKPE-EKVPVLIPKKEKPPPAK- 10003

Query: 138   EKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYG 197
                      P    K + EE +          P+  P     PP ++P +VP+  PV   
Sbjct: 10004 --------VPEVPKKPVPEEKV----------PVPVPKKVEAPPAKVP-EVPK-KPV--- 10040

Query: 198   TVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIV 257
               +   + A   V A   +  E   K  P  K P+PV + V                   
Sbjct: 10041 PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV------------------- 10081

Query: 258   SIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLT 317
                E P P  P       R  +  P +     + +F   I    E+    E+ +P     
Sbjct: 10082 ---EAPPPKVPK-----KREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLP----- 10128

Query: 318   SCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVK 377
                E  + LP    ++++  +   + P +           E+    E +   E  V   +
Sbjct: 10129 ---EEEEVLP---EEEEVLPEEEEIPPEE----------EEVPPEEEYVPEEEEFVP--E 10170

Query: 378   QEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAAT 437
             +EVLP     E+    P    +  I   +T   V   P     PPA  P  P  V     
Sbjct: 10171 EEVLP-----EVKPKVPVPAPVPEIKKKVTEKKV-VIPKKEEAPPAKVPEVPKKVEEKRI 10224

Query: 438   TVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVE--ADGQTEEILDSQNLNSRRS 495
              +      + V+ V EE E       E  +E  +  EVE  A  +  E++  + +    +
Sbjct: 10225 ILPKEEEVLPVE-VTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVI-KKAVPEAPT 10282

Query: 496   PVPAQIAITVPKTWKK-PKDRTRTTEEMLEA------ELELKAEEELSIDKVLESE---- 544
             PVP ++     K  KK P+++     +  EA      E+  K  E+  +    E+     
Sbjct: 10283 PVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAK 10342

Query: 545   -----QDKMSQGFHPE---RDPSDLKKVKAVEENGEEAEPVRNGAESVSEGE 588
                  ++K+S  F  E   ++  +L+ V+A  E   E E      E   EGE
Sbjct: 10343 GRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGE 10394



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 83/392 (21%), Positives = 148/392 (37%), Gaps = 47/392 (11%)

Query: 217  KQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVAR 276
            K  EK  P P      PV+  +    ++ +E +  + T +  +++  +P  P+  + V  
Sbjct: 9168 KVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKV-QVTKVPEVSKKIVPQKPSR-TPVQE 9225

Query: 277  STIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDIC 336
              I     +  + + + +   +++   +S  E+ + +    +  E    + T E      
Sbjct: 9226 EVIEVKVPAVHTKKMVIS---EEKMFFASHTEEEVSV----TVPEVQKEIVTEEKIHVAI 9278

Query: 337  KKPCSVAPNDIPLVSSTNLINEINGVSEKLSATE-SIVEIVKQEVLPLTLELEILENP-P 394
             K     P             ++  + EK +  E + V I K+   P     E+ + P P
Sbjct: 9279 SKRVEPPP-------------KVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP 9325

Query: 395  EEMKLECIPAPITPSTVPSFPPTPPTPPASP-PHTPVIVPAAATTVSSPSAAITVQR--- 450
            EE K    P P+ P   P+ PP  P  P  P P   + VP A    + P+    VQ+   
Sbjct: 9326 EEKK----PVPV-PKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVV 9380

Query: 451  -------VLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNS-RRSPVPAQ-I 501
                   V + +ES    + E  K+   +       + EE+     + +  + PVP + +
Sbjct: 9381 TEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKV 9440

Query: 502  AITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSID-----KVLESEQDKMSQGFHPER 556
            A+ VP   K P  R   +++ +  E    AEE+LS       +V   E     +  + E 
Sbjct: 9441 AVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEE 9500

Query: 557  DPSDLKKVKAVEENGEEAEPVRNGAESVSEGE 588
            +      V   EE  EE E      E + E E
Sbjct: 9501 EEGVSISVYREEEREEEEEAEVTEYEVMEEPE 9532



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 137/657 (20%), Positives = 219/657 (33%), Gaps = 134/657 (20%)

Query: 133   PPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPT--PPQQLPSQVPE 190
             PP K   K +  ++P     ++ ++I+     R P  P   PT  P   PP+++   VPE
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEV---VPE 10507

Query: 191   HSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPS------PVLRLVLSGEKK 244
                 V    +    A    V  A  +   EK  P P  K P       P +      EKK
Sbjct: 10508 KKVPVPPAKKPE--APPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKK 10565

Query: 245   EQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELS 304
               E       AI    E P P  P     V       P     ++ P             
Sbjct: 10566 VPE-------AIPPKPESPPPEVPEAPKEVV------PEKKVPAAPP------------K 10600

Query: 305   SPREDTIPIPSLTS--CTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGV 362
              P    + +P        E   P+P         KKP  V P  +P V           V
Sbjct: 10601 KPEVTPVKVPEAPKEVVPEKKVPVPPP-------KKP-EVPPTKVPEVPKV-------AV 10645

Query: 363   SEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPP 422
              EK      + E +  +  P +   E+ E P EE+ LE  PA +     P+ PP    PP
Sbjct: 10646 PEK-----KVPEAIPPK--PESPPPEVFEEP-EEVALEEPPAEVVEEPEPAAPPQVTVPP 10697

Query: 423   --------------ASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKE 468
                             P   PV VP     V        V  V ++ E+    + E  KE
Sbjct: 10698 KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV--VPKKPEAPPAKVPEVPKE 10755

Query: 469   IQNKIEVEADGQTEEILDSQNLNSRRSPV-PAQIAITVPKTWKKPKDRTRTTEEMLEAEL 527
             +  + +V A  +  E+  ++     + PV   + A+ VP+  + P        E +  E 
Sbjct: 10756 VVPEKKV-AVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEE 10814

Query: 528   ELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEG 587
             E+  EEE  +  V E E+ ++     P   P + KK+       E+  PV          
Sbjct: 10815 EIAPEEEKPV-PVAEEEEPEVP----PPAVPEEPKKIIP-----EKKVPVIK-------- 10856

Query: 588   EGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPP 647
                                  KPE+  P + E +K  ++  L           KP   PP
Sbjct: 10857 ---------------------KPEAPPPKEPEPEKVIEKPKL-----------KPRPPPP 10884

Query: 648   ISDVVLDKINQPKLPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPG 707
                   + + +    ++ +  + +P  P           + PGG       +  R+ +P 
Sbjct: 10885 PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPK 10944

Query: 708   QRREPRKIITVSVKED---VHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSI 761
             +    + ++    +E+   V  KK E   KP+          E ++   + ++ R I
Sbjct: 10945 EEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI 11001



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 107/518 (20%), Positives = 179/518 (34%), Gaps = 99/518 (19%)

Query: 114   PSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGR 173
             P +PV +     VPT+ + PPAK  KK             + EE +     +   PP   
Sbjct: 9794  PVKPVPEEP---VPTKPKAPPAKVLKKA------------VPEEKVPVPIPKKLKPP--- 9835

Query: 174   PTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSP 233
             P   P  P+++  +    S       +    AA  P+       +E+ P P    K  +P
Sbjct: 9836  PPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVP---RKEVAP 9892

Query: 234   VLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIF 293
              +R+    ++ E E    E   +  + E  +      +                   P+ 
Sbjct: 9893  PVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV------VPVI 9946

Query: 294   TTAIDDRCELSSPRE-DTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSS 352
                + +      P E   +P+P          P        ++ KKP    P  IP    
Sbjct: 9947  PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVP--------EVPKKPEEKVPVLIPKKEK 9998

Query: 353   TNLINEINGVSEKLSATESI-VEIVKQEVLPLTLELEILENPPEEMKLECIPAP----IT 407
                  ++  V +K    E + V + K+   P     E+ + P  E K+  +PAP      
Sbjct: 9999  PPPA-KVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVP-VPAPKKVEAP 10056

Query: 408   PSTVPSFP---------PTP-------PTPPASPPHTPVIVPAA---ATTVSSPSAAITV 448
             P+ VP  P         PTP       P P       PV VP A      V      +  
Sbjct: 10057 PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116

Query: 449   QRVLEEDESI----RTCLSEDAKEIQNKIEV-----------EADGQTEEILDSQNLNSR 493
             + VL E+E +       L E+ + +  + E+           E   + EE +  + +   
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPE 10176

Query: 494   ---RSPVPAQI----------AITVPKTWKKPKDRTRTTEEMLEAELEL--KAEEELSID 538
                + PVPA +           + +PK  + P  +     + +E +  +  K EE L ++
Sbjct: 10177 VKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVE 10236

Query: 539   KVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEP 576
                E E++ +S+   PE  PS       +EE  E A P
Sbjct: 10237 VTEEPEEEPISEEEIPEEPPS-------IEEVEEVAPP 10267


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 110/448 (24%), Positives = 159/448 (35%), Gaps = 47/448 (10%)

Query: 15   PQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRH- 73
            P   PP      ++PS +    TP A   + +        P P   P  P    P  +  
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT---PPPKGAPTPPAATPPSLKGG 1277

Query: 74   -SGPPYVGPPQQYPVQPPGP--GPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQ 130
             + PP+ G P    V PP P  GP    P     P A  TP  P        P   PT  
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA-ATPPSPKGSPGTPPPKGAPTPP 1336

Query: 131  Q-PPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI------GRPTSTPTPPQQ 183
               PP+ +   T+    P+  G   T     G     PTPP       G P  TP  P++
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG-----PTPPAATPSHKGGPAMTPPSPKR 1391

Query: 184  LPS-QVPEHSPVVYGTVE-SAHLAASTPVT---AASDQKQE-EKPKPDPVLKSPSPVLRL 237
             P+   P+  P     +  S   A +TPVT   AA+  K +   P   PV    +P    
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451

Query: 238  VLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAI 297
               G       +   T   V+      PP+P  V++ + S   AP + A    P     I
Sbjct: 1452 PKGGPATPSS-KGDPTLPAVTPPSPKEPPAPKQVAT-SSSPKKAPATPAPMGAPTLPAVI 1509

Query: 298  DDRCELSSPREDTIPIPSLTSCTETSDPL-PTNENDDDICKKPCSVAPNDIPLVSSTNLI 356
                  SSP+E    +P+  S     DP+ PT        K P ++AP +  +  +  + 
Sbjct: 1510 P-----SSPKE----VPATPSSRR--DPIAPTATLLSK--KTPATLAPKEALIPPAMTVP 1556

Query: 357  NEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPP 416
            +     +             K+   P  +     +  P   +L   PA  +PS     P 
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS-----PK 1611

Query: 417  TPPTPPASPPHTPVIVPAAATTVSSPSA 444
              PTPPA  P +P   PA      +P++
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTS 1639



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 100/449 (22%), Positives = 154/449 (34%), Gaps = 49/449 (10%)

Query: 8    RSPFFQRPQIQPPR-ATIPNS------SPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV 60
            R P    P+  P   A IP S      +P  R GA TP+        +        P  +
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT-------PVSL 1443

Query: 61   PQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQ 120
             + P    P+   + P   G P    V PP P      P P     +      P+ P   
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE---PPAPKQVATSSSPKKAPATPAPM 1500

Query: 121  SAPI---IVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTST 177
             AP    ++P+  +  PA    +    RDP      +  +      +  P   +  P  T
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSR----RDPIAPTATLLSK--KTPATLAPKEALIPPAMT 1554

Query: 178  PTPPQQLPS-QVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVL-----KSP 231
               P++ P+   P+ +P    + E++   A TP T       +E   P  V      ++P
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614

Query: 232  SPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQP 291
            +P      S EK         T     +    L  SPT+ +SV    + A    A    P
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT-CKMGATVPQASKGLP 1673

Query: 292  IFTTAIDDRCELSSPREDTIPI--------PSLTSCTETSDPLPTNENDDDICKKPCS-V 342
                    +  L +P  ++ PI        P     + TS P+  + +  +  K P S V
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733

Query: 343  APNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLE-LEILENPPEEMKLEC 401
            AP  +  V   +      G     S    +     +   PLT    E +   PE   +  
Sbjct: 1734 APAPLLPVQKDSS-KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 402  IPAP-----ITPSTVPSFPPTPPTPPASP 425
             P+P     + PS VP+ PP     P+SP
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 106/467 (22%), Positives = 154/467 (32%), Gaps = 70/467 (14%)

Query: 5    PQTRSPFFQRPQIQPPRATIPN-----SSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYP 59
            P T SP   +    PP AT P+     ++P  +    TP A   + +  +     P P  
Sbjct: 1094 PATPSP---KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT---PPPKG 1147

Query: 60   VPQGPQYCIPQYRH--SGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNA-YGTPFYPSQ 116
             P  P    P  +   + PP  G P      PP P      P P   P     TP  P  
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207

Query: 117  PVYQSAPIIVPTQQQ--PPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNP-TPPIGR 173
             +   +P   PT     PP  K    T     P+  G   T           P TPP   
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLAT-----PSPKGAPTTPAATPPSPKGGPATPP--- 1259

Query: 174  PTSTPTPPQQLPSQVPEH--SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSP 231
            P   PTPP   P  +     +P   G    A +   +P    +    +  P P P    P
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPP 1318

Query: 232  SPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQP 291
            SP          K   G      A       P PP+ T  S     T+ A T S+     
Sbjct: 1319 SP----------KGSPGTPPPKGA-------PTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361

Query: 292  IFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVS 351
              ++        ++P     P  ++T  +    P   +   D        ++P   P   
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGP--AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419

Query: 352  STNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPS-- 409
                      V+ + +AT S  ++    V P++L+     + P+         P TPS  
Sbjct: 1420 ----------VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-------GPATPSSK 1462

Query: 410  ---TVPSF-PPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVL 452
               T+P+  PP+P  PPA         P  A    +P  A T+  V+
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 116/565 (20%), Positives = 192/565 (33%), Gaps = 97/565 (17%)

Query: 23  TIPNSSPSIRPGAQTPTAVYQANQHIMMVNHL-----PMPYPVPQGPQYCIPQYRHSGPP 77
           T+P +   + P  Q  TAV   +  + +   L      +P P    PQ C     +   P
Sbjct: 8   TVPATEQEL-PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP 66

Query: 78  YVGP------PQQYPVQPPGPGPFYP----GPGPGDFPNAYGTPFYPSQPVYQSAPIIVP 127
           +  P      P + P      G   P       P   PN  G P  P+     S P+I P
Sbjct: 67  FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS-PMIAP 125

Query: 128 TQQQPPPAKREKKTIRIRD----------PNQGGKDITEEIMSGGG-------------- 163
           T +  P +      + +            PN      +  +   G               
Sbjct: 126 TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185

Query: 164 ---SRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVES--AHLAASTPVTAASDQKQ 218
              ++ P+  +  P  TP+PP  + S VP H      +++S  A L  +TP T  +    
Sbjct: 186 TNLNKVPSEVVPNPKGTPSPPC-IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244

Query: 219 EEKPKP-DPVLKSP------------SPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLP 265
           + K      VL SP            SP   L LS +       + +T    +  + P+ 
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS 304

Query: 266 P----SPTTVSSVARSTIAAPTS-SALSSQPIFTTAIDDR---CELSSPREDTIPIPS-- 315
                +P   SS     +   T  SALS   + T ++D         S R    P+PS  
Sbjct: 305 LGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRN 364

Query: 316 -LTSCTETSDPL---PTNENDDDICKKPCSVAPN-----DIPLVSSTNLI--NEINGVSE 364
            +   T  + P+     ++    I    CS + +        L  +T+LI  +  N    
Sbjct: 365 EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYH 424

Query: 365 KLSATESIVEIVKQEVLPLTLELEILENPPEEMKLE-CIPAPITPSTVPSFPPTPPTPPA 423
                +  V  V    L +T    I   P    ++  C+  P++   + +  PT P    
Sbjct: 425 YPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALV 484

Query: 424 SPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEE 483
             P    + P   +T  + +  I V   L +         ED K + + + V+    T++
Sbjct: 485 MAP----VAPKEPSTQVATTLRIPVSPPLPD--------PEDLKNLPSSVLVKF--PTQK 530

Query: 484 ILDSQNLNSRRSPV-PAQIAITVPK 507
            L +   +   +P  PAQ  +T  K
Sbjct: 531 DLQTVPASLEGAPFSPAQAGLTTKK 555



 Score = 38.5 bits (88), Expect = 0.052
 Identities = 108/476 (22%), Positives = 150/476 (31%), Gaps = 61/476 (12%)

Query: 20   PRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYV 79
            P    P  +P++   + +P    +A      +   P P   P  P    P  +  GP   
Sbjct: 900  PATPAPKQAPALSMTSSSPKKA-RATPAPKGIPASPSPKGAPTPPAATPPSPK-GGPATP 957

Query: 80   GP---PQQYPVQPPGP--GPFYPGPGPGDFPNAY------GTPFYPSQPVYQSAPIIVPT 128
             P   P      PP P  GP  P P     P A       G P  PS     + P + P 
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 129  QQQPPPA-----KREKKTIRIRDPNQGGKDITEEIMSGG----GSRNPTPPIGRPT---- 175
              +  PA     K          P+  G      +  G      +  P+P  G  T    
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077

Query: 176  STPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASD-QKQEEKPKP-DPVLKSPSP 233
              PTPP   P   P+  P       +    A+TP +          K  P  P    PSP
Sbjct: 1078 GAPTPPAATPPS-PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136

Query: 234  VLRLVLSGEKKEQEGQTSETTAIVSIAELPLPP---SPTTVSSVARST---IAAPTSSAL 287
               L     K      T   T       L  PP   +PTT ++   S    +A P+    
Sbjct: 1137 KGGLATPPPKGAP--TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194

Query: 288  SSQPIFTTAIDDRCELSSPRED--------TIPIPSLTSCTETSDPLPTNENDDDICKK- 338
             + P   T    +  L++P           T P P     T +    PT         K 
Sbjct: 1195 PTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253

Query: 339  -PCSVAPNDIPLVSSTNLINEINGVS---EKLSATESIVEIVKQEVLPLTLELEILENPP 394
             P +  P   P   +    +   G++    K +   ++V     +  P T       +PP
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT-------SPP 1306

Query: 395  EEMKLECIPAPITPSTVPSFPPT--PPTPPASPPHTPVIVPA-AATTVSSPSAAIT 447
            +         P +P   P  PP    PTPPA  P +P   P   ATT SS     T
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362



 Score = 36.6 bits (83), Expect = 0.20
 Identities = 73/301 (24%), Positives = 102/301 (33%), Gaps = 79/301 (26%)

Query: 169 PPIGRP-----------TSTPTPPQQLPSQVPEHSPVVYGTVES----AHLAASTPVTAA 213
           PP G P           TS   P    P + P        T  S     +LA S      
Sbjct: 740 PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799

Query: 214 SDQKQEEKPK-------PD-PV--LKSP-SPVLRLVLSGEKKEQEGQTSETTAIVSIAEL 262
           S   Q ++P        PD P+  L SP SPV    L       +G         S    
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS---- 855

Query: 263 PLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTET 322
           P PPSP            APT SA++  P+            SP+  T+P     + +  
Sbjct: 856 PTPPSPK----------GAPTPSAVT--PL------------SPKGVTLPPKETPTPSVV 891

Query: 323 SDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLP 382
           + P P         + P + AP   P +S T+         +K  AT +       + +P
Sbjct: 892 NLPFPK--------EGPATPAPKQAPALSMTS------SSPKKARATPA------PKGIP 931

Query: 383 LTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSP 442
            +   +    PP          P TPS     P   PTPPA+ P +P   PA  +   +P
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPS-----PKWAPTPPAATPPSPKGGPATPSPKGAP 986

Query: 443 S 443
           +
Sbjct: 987 T 987



 Score = 34.7 bits (78), Expect = 0.75
 Identities = 69/325 (21%), Positives = 105/325 (32%), Gaps = 52/325 (16%)

Query: 149  QGGKDITEEIMSGGGSRNPTPPIGRPTSTPT------------PPQQLPSQ------VPE 190
            QG KD      S   + +PTPP  +   TP+            PP++ P+        P+
Sbjct: 844  QGSKD------SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897

Query: 191  HSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSP--VLRLVLSGEKKEQEG 248
              P      ++  L+    +T++S +K    P P  +  SPSP        +     + G
Sbjct: 898  EGPATPAPKQAPALS----MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953

Query: 249  QTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPRE 308
              + +           PPSP    +      A    +A    P    A        +P  
Sbjct: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013

Query: 309  DTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSA 368
             T P P     +  + P P   +       P +  P+     ++T L         K + 
Sbjct: 1014 VTPPSPK---GSPAATPFPKGASTP-----PAATPPSPKGSPAATPL--------PKGAP 1057

Query: 369  TESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPP------ 422
            T     +   +  P T  L+    PP          P TPS   +  P   TPP      
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117

Query: 423  ASPPHTPVIVPAAATTVSSPSAAIT 447
            A+PPH       AAT  S      T
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLAT 1142



 Score = 31.2 bits (69), Expect = 8.3
 Identities = 43/199 (21%), Positives = 71/199 (35%), Gaps = 23/199 (11%)

Query: 248 GQTSETTAIVSIAELPLPPSPTTVSSVARS-TIAAPTSSALSSQPIFTTAIDDRCELSSP 306
           G+ +ET       ELP P + T V  ++ + ++ A       + P   +    +C LS+ 
Sbjct: 3   GEATETVPATE-QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 307 REDT-IPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEK 365
            + +  P PS  + T    P P + +   +       AP  +P     NLI      +  
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLP-----NLIGPPISPAAL 116

Query: 366 LSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASP 425
             A+  I   +K               P     L  +   + P +V      PP    SP
Sbjct: 117 ALASPMIAPTLKG-------------TPSSSAPLALVA--LAPHSVQKSSAFPPNLLTSP 161

Query: 426 PHTPVIVPAAATTVSSPSA 444
           P   V    +  T+S+P A
Sbjct: 162 PSVAVAESGSVITLSAPIA 180


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 113/493 (22%), Positives = 172/493 (34%), Gaps = 82/493 (16%)

Query: 5    PQTRSPFFQRPQIQPPRATI-PNSSPSIRPG-AQTPTAVYQANQHIMMVNHLPMPYPVPQ 62
            P  R P    P +  PR T+ P   P+   G A+ P       + ++ + H P P     
Sbjct: 1329 PAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388

Query: 63   GPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA 122
             P         + P  +  P   P   PGP    P P P   P A       S P+  S 
Sbjct: 1389 APG--------AAPLTISSPLHVPSSLPGPASS-PMPIPNSSPLASPVSSTVSVPLSSSL 1439

Query: 123  PIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI--------GRP 174
            PI VPT   P PA     TI I  P      +T          + TPP+        G P
Sbjct: 1440 PISVPTTL-PAPASAPL-TIPISAP------LTVSASGPALLTSVTPPLAPVVPAAPGPP 1491

Query: 175  TSTP---------------TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQ--K 217
            +  P               T P    SQ P H  ++  T        ST   A S     
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551

Query: 218  QEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTT----VSS 273
                  P P   +P+P    +L+      +   +    + +     L PSP      +  
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611

Query: 274  VARSTIAAPT-SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLT-SCTETSDPLPTNEN 331
            +A S  AAP  +S+ +  P+   +      L+S      P P L  S T+T  P P    
Sbjct: 1612 LAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPV--- 1668

Query: 332  DDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEI----------VKQEVL 381
                        P+ +P  +ST  +     ++  L  +     +             + L
Sbjct: 1669 ------------PSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTL 1716

Query: 382  PLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPAS-----PPHTPVIVPAAA 436
             LT    ++  P + + L   P P+ P+   S  P PP  PAS     P HT  + PA++
Sbjct: 1717 SLTPASSLVPTPAQTLSLAPGP-PLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASS 1775

Query: 437  T-TVSSPSAAITV 448
            + ++ +P++  T+
Sbjct: 1776 SASLLAPASVQTL 1788



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 112/474 (23%), Positives = 166/474 (35%), Gaps = 75/474 (15%)

Query: 24   IPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIP-QYRHSGPPYVGP- 81
            IPNSSP   P + T +    ++  I +   LP P   P       P     SGP  +   
Sbjct: 1417 IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSV 1476

Query: 82   -PQQYPVQPPGPGPFYPGPGPGDFPNAYG---------------TPFYP----------- 114
             P   PV P  PGP    P  G  P+A                 TP +P           
Sbjct: 1477 TPPLAPVVPAAPGPPSLAPS-GASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP 1535

Query: 115  ---SQPVYQSAPIIVPTQ-------QQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGS 164
               S      +P++VP           P PA  +   +                M+   +
Sbjct: 1536 GLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQT 1595

Query: 165  R----NPTPPIGR-PTSTPTP---PQQLPSQVPEHSPVVY-GTVESAHLAASTPVTA--- 212
                 +P PP+   P   P+P   P    SQ P   PV+   +     LA+++PV A   
Sbjct: 1596 AILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPV--PVMAPSSTPGTSLASASPVPAPTP 1653

Query: 213  ----ASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSP 268
                +S Q     P P P L SP+    L L+       G +S +  +      P  P P
Sbjct: 1654 VLAPSSTQTMLPAPVPSP-LPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFP 1712

Query: 269  TTVSSVARSTIAAPTSSALSSQ-------PIFTTAIDDRCELSSPREDTIPIPSLT---S 318
            T   S+  ++   PT +   S        P  T ++     L+ P     P P+ T   +
Sbjct: 1713 TQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLA-PASPVGPAPAHTLTLA 1771

Query: 319  CTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQ 378
               +S  L    +   +   P  V P   P  + T  +   +  S    A+  +V     
Sbjct: 1772 PASSSASLLAPASVQTLTLSPAPV-PTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830

Query: 379  EVLPLTL--ELEILENPPEEMKLECIPAPITPSTVPSFP-PTPPTPPASPPHTP 429
              LP+T+   L + ++ P+ + L   P P  PST  SF  P P   P  PP +P
Sbjct: 1831 APLPVTMVSRLPVSKDEPDTLTLRSGP-PSPPSTATSFGGPRPRRQPPPPPRSP 1883



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 97/444 (21%), Positives = 155/444 (34%), Gaps = 94/444 (21%)

Query: 49   MMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPG-PGPGDFPNA 107
            M VN +  P P  +G    +     +    +GP    PV+PP PGP     P PG  P  
Sbjct: 992  MKVNRMLQPVPKQEGRTVVVVNNPRAP---LGP---VPVRPP-PGPELSAQPTPGPVPQV 1044

Query: 108  YGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSG---GGS 164
                   S     + P ++P  + P P       +    PN G          G   G S
Sbjct: 1045 LPASLMVSAS--PAGPPLIPASRPPGPV-----LLPPLQPNSGSLPQVLPSPLGVLSGTS 1097

Query: 165  RNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYG-TVESAH----LAASTPVTAASDQKQE 219
            R PTP +    + P P +  P+  P  S ++   TV   +     AA+T  T  +     
Sbjct: 1098 RPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTT 1157

Query: 220  EKPKPDPVLKSPSPVLRLVLSGEKKEQ--EGQTSETTAIVSIAELPLPPS---------- 267
              P P P  +      RL+LS + + +   G+      + S+A+ P+  +          
Sbjct: 1158 AVPAPTPAPQ------RLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQI 1211

Query: 268  -------------------PTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPRE 308
                               P  +       ++A     L SQP     I    +  +P  
Sbjct: 1212 QGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALI----QAVAPTP 1267

Query: 309  DTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIP--LVSSTNLINEINGVSEKL 366
               P+  L S T ++ P PT  +          +A N +P  +V++T ++          
Sbjct: 1268 GPTPVSVLPSSTPSTTPAPTGLS--------LPLAANQVPPTMVNNTGVV---------- 1309

Query: 367  SATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPIT--PSTVPSFPPTPPTPPA- 423
               + +V    ++ L     L     PP       +PA +   P+  P   PTP    A 
Sbjct: 1310 ---KIVVRQAPRDGLTPVPPLAPAPRPPS----SGLPAVLNPRPTLTPGRLPTPTLGTAR 1362

Query: 424  SPPHTPVIVPAAATTVSSPSAAIT 447
            +P  TP +V      V SPS  ++
Sbjct: 1363 APMPTPTLVRPLLKLVHSPSPEVS 1386



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 83/315 (26%), Positives = 116/315 (36%), Gaps = 61/315 (19%)

Query: 174  PTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAAS-TPVTAASD---------QKQEEKPK 223
            PT  PTP   LPS  P  +P   G   S  LAA+  P T  ++         Q   +   
Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPAPTGL--SLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLT 1322

Query: 224  PDPVL----KSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLP------------PS 267
            P P L    + PS  L  VL+       G+    T   + A +P P            PS
Sbjct: 1323 PVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPS 1382

Query: 268  PTTVSS---VARSTIAAP--TSSALSSQPIFTTAIDDRCELSSPREDTIPIP---SLTSC 319
            P   +S    A  TI++P    S+L         I +   L+SP   T+ +P   SL   
Sbjct: 1383 PEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPIS 1442

Query: 320  TETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQE 379
              T+ P P +             AP  IP+  S  L    +G +   S T  +  +V   
Sbjct: 1443 VPTTLPAPAS-------------APLTIPI--SAPLTVSASGPALLTSVTPPLAPVVPAA 1487

Query: 380  VLPLTLELEILENPPEEMKLECIPAP-ITPSTVPSFP----PTPPTPP-----ASPPHTP 429
              P +L           + L    AP ++ S  P  P    PT    P      +P  +P
Sbjct: 1488 PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSP 1547

Query: 430  VIVPAAATTVSSPSA 444
            V+VPA+A     PSA
Sbjct: 1548 VLVPASALASPFPSA 1562



 Score = 38.1 bits (87), Expect = 0.068
 Identities = 72/338 (21%), Positives = 128/338 (37%), Gaps = 41/338 (12%)

Query: 139  KKTIRIRDPNQGGKDITEEIMSG-----GGSRNPTPPIGRPTSTPTPPQQLPSQ--VPEH 191
            +++ + + P + G  ++E +        G +  P     +  ST TPP+  P++  VP  
Sbjct: 2380 RRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRP 2439

Query: 192  SPVVYGTVESAHLA--ASTPVTAASDQKQEEKPKPDPVLKSPSPV----LRLVLSGEKKE 245
            +P    T  SA  A  A  PV  ++         P P+  +P+P+    + ++ S     
Sbjct: 2440 APRPRPTPASAPAAIPALVPVPVSA---------PVPI-SAPNPITILPVHILPSPPPPS 2489

Query: 246  QEGQTSETTAIVSIAELPLP---PSPTTVSSVARSTI------AAPTSSALSSQPIFTTA 296
            Q    S        A  P P   P P     V  S+       + P S+++++ P+    
Sbjct: 2490 QIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRP 2549

Query: 297  IDDRCELSSPREDTIPIPSLTSCTETS-------DPLPTNENDDDICKKPCSVAPNDIPL 349
              + C  +    +++ + S+ S   +S       D LP       + +K  S+ P+   L
Sbjct: 2550 EAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSL 2609

Query: 350  VSSTNLINEINGVSEKLSATESIVEIVKQ-EVLPLTL-ELEILENPPEEMKLECIPAPIT 407
                  I          SA  + + ++ + E LPL + E   LE PP     E +  P+ 
Sbjct: 2610 TLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLE 2669

Query: 408  PSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAA 445
                        TP +SP     +V A     S+ S+A
Sbjct: 2670 ADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSA 2707



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 69/283 (24%), Positives = 99/283 (34%), Gaps = 59/283 (20%)

Query: 222  PKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAA 281
            P+P PV    + +L+ V      +QEG+T     +V+    PL P P          +  
Sbjct: 985  PRPKPVKMKVNRMLQPV-----PKQEGRT---VVVVNNPRAPLGPVP----------VRP 1026

Query: 282  PTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPL-PTNENDDDICKKPC 340
            P    LS+QP              P    +P   + S +    PL P +     +   P 
Sbjct: 1027 PPGPELSAQPT-----------PGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPL 1075

Query: 341  SVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
                  +P V  + L     GV   LS T            P T  L +   PP  ++L 
Sbjct: 1076 QPNSGSLPQVLPSPL-----GV---LSGTSR----------PPTPTLSLKPTPPAPVRLS 1117

Query: 401  CIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRV-LEEDESIR 459
              P P + S +          P + P      PAAATT S+ +A  T   V        R
Sbjct: 1118 PAPPPGSSSLLK---------PLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQR 1168

Query: 460  TCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRS-PVPAQI 501
              LS D +      EV + GQ   +      N+  S P+  QI
Sbjct: 1169 LILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQI 1211



 Score = 35.4 bits (80), Expect = 0.44
 Identities = 61/234 (26%), Positives = 87/234 (37%), Gaps = 28/234 (11%)

Query: 392  NPPEEMKLECIPAPITPSTVP--SFPPTPPTPPASPP--HTPVIVPAAATTVSSPSAAIT 447
            NP   + +  +P+P  PS +P  S P   P P  +PP  HTP   P A T + +PS+ + 
Sbjct: 2472 NPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTP---PPAQTCLVTPSSPL- 2527

Query: 448  VQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPK 507
                L    S+    S     +  + E E   Q     +S  L S  S   + +++ VP 
Sbjct: 2528 ----LLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSL-VP- 2581

Query: 508  TWKKPKDRTRTTEEML---EAELELKAE------EELSIDKVLESEQDKMSQGFHPERDP 558
                PKD      E+L   E  L L         E  SI    E E    ++G      P
Sbjct: 2582 ----PKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLP 2637

Query: 559  SDLKKVKAV-EENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPE 611
               +    V E NG E  P     E + E    D  S     +    + P KP+
Sbjct: 2638 EGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQ 2691


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 99/451 (21%), Positives = 152/451 (33%), Gaps = 63/451 (13%)

Query: 9   SPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCI 68
           SP F+   + PP   +P S P        P                PM  P  + P    
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASRLSPPP------------EESPMSPPPEESPMSPP 593

Query: 69  PQYRHSGPPYVG-----PPQQYPVQPPGPGPFYPGPGPGDFPNA---YGTPFYPSQPVYQ 120
           P+     PP+       PP++ P+ PP P      P P D P +     +P  P   V +
Sbjct: 594 PEASRLFPPFEESPLSPPPEESPLSPP-PEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652

Query: 121 SAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP 180
            +P+ V ++  PPP +          P     +          SR   PP   PTS P  
Sbjct: 653 LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE---------ASRLSPPPEDSPTSPP-- 701

Query: 181 PQQLPSQVPEHSPVVYGTVESAHLAA--STPVTAASDQKQEEKPKPDPVLKSPSPVLRLV 238
           P+  P+  P    ++   +E + L      P      +     P+P+    SP P    +
Sbjct: 702 PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761

Query: 239 LSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSAL-----SSQPIF 293
               ++       E   + ++ E P       +S  A     +P    L     + +P  
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEP------HLSPQAEGPHLSPQPEELHLSPQTEEPHL 815

Query: 294 TTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNEN-DDDICKKPCSVAPNDIPLVSS 352
           +   ++ C    P E  +   S   C     P P   +   ++ K P S  P   P    
Sbjct: 816 SPVPEEPCLSPQPEESHLSPQSEEPCLS---PRPEESHLSPELEKPPLSPRPEKPP---- 868

Query: 353 TNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPA--PITPST 410
                E  G               +  + PL  E  + E  P E  L  +P   P++PS 
Sbjct: 869 -----EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE--PGEPPLSPLPEELPLSPSG 921

Query: 411 VPSF-PPTPPTPPASPPHTPVIVPAAATTVS 440
            PS  P   P  P  PP +P+I  AA   +S
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALS 952



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 97/473 (20%), Positives = 159/473 (33%), Gaps = 59/473 (12%)

Query: 3    SQPQTRSPFFQRPQ---IQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYP 59
            S P   SP    P+   + PP    P S P        P  V + +   ++    P P  
Sbjct: 609  SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668

Query: 60   VPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVY 119
             P  P                PP++ P  PP P      P P D P +      P+ P  
Sbjct: 669  SPLSP----------------PPEESPTSPP-PEASRLSPPPEDSPTSPPPEDSPASPPP 711

Query: 120  QSAPIIVPTQQQP--PPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTST 177
            + + + +P ++ P  P  +  +   R   P+   +     +       + +P    P  +
Sbjct: 712  EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLS 771

Query: 178  PTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEE--KPKPDPVLKSPSPV- 234
            P P +     VPE  P +    E  HL+        S Q +E    P P+    SP P  
Sbjct: 772  PQPEEPCLCAVPEE-PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830

Query: 235  LRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAA-----------PT 283
              L    E+     +  E+     + + PL P P           A            P+
Sbjct: 831  SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS 890

Query: 284  SSALSSQPIFTTAIDDRCELSSPREDTIPI-----PSLTSCTETSDPLPTNENDDDICKK 338
             S L  +P  +   +      SP  + +P+     PSL+      DPLP   +       
Sbjct: 891  LSPLLGEPALSEPGEPPL---SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947

Query: 339  PCSVAPN---DIPLVSSTNLINEI--------NGVSEKLSATESIVEIVKQEVLPLTLEL 387
            P +++P    + P  +  +   E           +S    A  +  E V   +LP +   
Sbjct: 948  PPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007

Query: 388  EILENPPEEMKLECIPAPITPSTVPSF-PPTPPTPPASPPHTPVIVPAAATTV 439
             +   P   + +E +P   +P    S  P   P    SPP  P+ VP+  + +
Sbjct: 1008 PV--GPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPI 1058



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 120/552 (21%), Positives = 184/552 (33%), Gaps = 77/552 (13%)

Query: 38  PTAVYQANQHIMMVNHLPMPYPVPQGPQYCI------------PQYR---HSGPPYVGPP 82
           P A+Y A Q      H+    P   GP  C             PQ     +   P + PP
Sbjct: 385 PDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPP 444

Query: 83  QQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTI 142
           ++ P+ PP P      P P     +      P+ P+ ++  +  P ++ P     E+  +
Sbjct: 445 EESPLSPP-PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 143 RIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVP-EHSPVVYGTVES 201
                +     + E  +S      P+P +  P S   PP+  P   P E SP+   +   
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLS--PPPEASPLSPPFEESPL---SPPP 558

Query: 202 AHLAASTPVTAAS-DQKQEEKPKPDPVLKSP-SPVLRLVLSGEKKEQEGQTSETTAIVSI 259
             L  S P  A+      EE P   P  +SP SP        E         E+      
Sbjct: 559 EELPTSPPPEASRLSPPPEESPMSPPPEESPMSP------PPEASRLFPPFEESPLSPPP 612

Query: 260 AELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSC 319
            E PL P P        S ++ P   +  S P   + +    E+S  R   +P+ S  S 
Sbjct: 613 EESPLSPPPEA------SRLSPPPEDSPMSPPPEESPMSPPPEVS--RLSPLPVVSRLSP 664

Query: 320 TETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQE 379
                PL     +      P +   +  P  S T+   E +  S     +   + + +  
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724

Query: 380 VLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASP-PHTPVIVPAAATT 438
           +LPL          PEE      P     S  P   P P  P  SP P  P + P A   
Sbjct: 725 LLPL----------PEE------PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768

Query: 439 VSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEI-LDSQNLNSRRSPV 497
             SP          + +E     + E+              Q EE+ L  Q      SPV
Sbjct: 769 HLSP----------QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV 818

Query: 498 PAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERD 557
           P +  ++         + +  + +  E  L  + EE       L  E +K      PE+ 
Sbjct: 819 PEEPCLS------PQPEESHLSPQSEEPCLSPRPEE-----SHLSPELEKPPLSPRPEKP 867

Query: 558 PSDLKKVKAVEE 569
           P +  +  A EE
Sbjct: 868 PEEPGQCPAPEE 879



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 83/357 (23%), Positives = 121/357 (33%), Gaps = 44/357 (12%)

Query: 94  PFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIR---IRDPNQG 150
           P  PG  P D P+A    +   Q   +   +     ++P P + E K +    ++   Q 
Sbjct: 374 PPEPGDTPTDEPDAL---YVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL 430

Query: 151 GKDITEEI-MSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTP 209
              + EE+ +      +P  P    + T  PP+      P          E+ HL+    
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE 490

Query: 210 VTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPP--- 266
            +  S   +E    P P     SP+    LS  ++       ET         PL P   
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550

Query: 267 -SPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDP 325
            SP +       T   P +S LS  P       +   +S P E++   P      E S  
Sbjct: 551 ESPLSPPPEELPTSPPPEASRLSPPP-------EESPMSPPPEESPMSPP----PEASRL 599

Query: 326 LPTNENDDDICKKPCSVAPNDIPL-----VSSTNLINEINGVS--EKLSATESIVEIVKQ 378
            P  E      + P S  P + PL      S  +   E + +S   + S      E+ + 
Sbjct: 600 FPPFE------ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653

Query: 379 EVLPLTLEL------EILENPPEEMKLECIPAPITPSTVPSFPPTPPTP---PASPP 426
             LP+   L        L  PPEE      P     S  P   PT P P   PASPP
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP 710



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 66/306 (21%), Positives = 88/306 (28%), Gaps = 40/306 (13%)

Query: 19   PPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPY 78
            PP+  +P   PS  P    P   Y              PYP P G     P    S  P 
Sbjct: 2164 PPQ--VPAQVPSQDPFGLAPA--YPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219

Query: 79   VGPPQQYPVQPPGPGPFYPG-PGPGDFPN--AYGTPFYPSQPVYQSAPIIVPTQQQPPPA 135
             G P ++   PPG     P  P P   P   +      P  P         P    PPP 
Sbjct: 2220 AGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL-LSPPPF 2278

Query: 136  KREKKTIRIR------------DPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTP----- 178
               +K + ++             PN G  D        GG    TP + +   TP     
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338

Query: 179  -------------TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPD 225
                          PP Q  +  P   P ++         A  P+T        E     
Sbjct: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398

Query: 226  PVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSS 285
            P    PS     V +  + +   Q+  T   +S       PSP T    +    + P S 
Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE--AFCPSPVTPRFQSPDPYSRPPSR 2456

Query: 286  ALSSQP 291
              S  P
Sbjct: 2457 PQSRDP 2462



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 62/296 (20%), Positives = 96/296 (32%), Gaps = 55/296 (18%)

Query: 64   PQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPG---PGDFPNAYGTPFYPSQPVYQ 120
            P   +P     G  ++  P Q P Q P   PF   P       FP A   P YP  P   
Sbjct: 2146 PAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTA--PPTYPPYPSPT 2203

Query: 121  SAPIIVPT---------------QQQPPPAKREKKT-----IRIRDPNQGGKDITEEIMS 160
             AP   P                   PP   R + +     ++ R P+     + E    
Sbjct: 2204 GAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263

Query: 161  GGGSRN----PTPPIGRP-TSTPTPPQQLPSQVPEHSPVVYGTVES----AHLAA----- 206
            GGG  +      PP G    +     ++L +  P + P   G V+S     HL       
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323

Query: 207  ----STPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKE---QEGQTSETTAIVSI 259
                  P+T  + Q + + P      + P P   L  S        + G  ++  A   +
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383

Query: 260  AELPLPPSPTTVSSVARSTI---------AAPTSSALSSQPIFTTAIDDRCELSSP 306
               P PP P +  ++   ++         A+P S + S  P+    +       SP
Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439



 Score = 34.7 bits (78), Expect = 0.75
 Identities = 111/470 (23%), Positives = 172/470 (36%), Gaps = 102/470 (21%)

Query: 4    QPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQ- 62
            Q Q ++   QR Q+Q  +A +  + P   PG QT        Q ++        +P PQ 
Sbjct: 4219 QQQLQALLMQR-QLQQSQA-VRQTPPYQEPGTQTSPL-----QGLLGCQPQLGGFPGPQT 4271

Query: 63   GP-QYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQS 121
            GP Q      R  GPP +  P       P  GP +P P P        +P  P +P    
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP-------SSPQEPKRPSQLP 4324

Query: 122  APII-VPTQQQPPPA-----KREKKTIRIRDPNQG-----GKDITEEIMSGGGSRNPTPP 170
            +P   +PT+ Q PP      K +  T+   +P  G        + + + S G    P  P
Sbjct: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTL---EPPPGRVSPAAAQLADTLFSKG--LGPWDP 4379

Query: 171  IGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKS 230
                  T  P Q   S VP H   V G V          V  AS    +++P+ +P    
Sbjct: 4380 PDNLAETQKPEQS--SLVPGHLDQVNGQV----------VPEASQLSIKQEPREEPCALG 4427

Query: 231  PSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIA--APTSSALS 288
               V        K+E  G+        +   L  P S      + +   A     S+   
Sbjct: 4428 AQSV--------KREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRG 4479

Query: 289  SQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIP 348
            S+ +       R E++   +       L    +     P+N+ +D   +KP +  P  + 
Sbjct: 4480 SEGL-------RAEINGHIDS-----KLAGLEQKLQGTPSNK-EDAAARKPLTPKPKRVQ 4526

Query: 349  -----LVSSTNLINEINGVSEKLSATESIVEIVKQE--VLPLTLELEILEN--------- 392
                 LVSS   + + +GV     A+E++++ +KQE  +LPLT E  I  N         
Sbjct: 4527 KASDRLVSSRKKLRKEDGV----RASEALLKQLKQELSLLPLT-EPAITANFSLFAPFGS 4581

Query: 393  -PPEEMKLECIPAPITPSTVPSFP------------PTPPTPPASPPHTP 429
              P   + + +        +P+ P              PPTPP+S P TP
Sbjct: 4582 GCPVNGQSQ-LRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTP 4630



 Score = 31.2 bits (69), Expect = 8.3
 Identities = 63/257 (24%), Positives = 95/257 (36%), Gaps = 43/257 (16%)

Query: 2    NSQPQT--RSPFFQRPQIQPPRA--TIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMP 57
            +S P++   +P  + P   PP A  T P   P +       + V  A+  +M     P+P
Sbjct: 966  DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME----PLP 1021

Query: 58   YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPG-----PGPFYP-GPGPGDFPNAYGTP 111
                  PQ C P  +HS  P   PP Q    PP      P P  P G   G    A    
Sbjct: 1022 ------PQ-CSPLLQHSLVPQNSPPSQ--CSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072

Query: 112  FYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPI 171
                +      P + P+   P P+        +  P        ++    G    P   I
Sbjct: 1073 METEKVSEPECPALEPSATSPLPSPMGD----LSCPAPSPAPALDDFSGLGEDTAPLDGI 1128

Query: 172  GRPTSTPTP---PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQ--------EE 220
              P S P P   P  L S++ + SPV+   ++   LA  TP+    + KQ        EE
Sbjct: 1129 DAPGSQPEPGQTPGSLASEL-KGSPVL---LDPEELAPVTPMEVYPECKQTAGQGSPCEE 1184

Query: 221  KPKP-DPVLKSPSPVLR 236
            + +P  PV  +P  +++
Sbjct: 1185 QEEPRAPVAPTPPTLIK 1201


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 102/455 (22%), Positives = 149/455 (32%), Gaps = 91/455 (20%)

Query: 4    QPQTRSPFFQRPQIQ---PPRATIPNSSPSI----------RPGAQTPTAVYQANQHIMM 50
            QPQ + P  Q P  Q   PP+AT P  SP +          +P + TPTA+   +   M 
Sbjct: 641  QPQAQQPP-QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMF 699

Query: 51   VNHLPMPYPVP-QGPQYCIP-QYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAY 108
            +       P+  +GP   +P     S PP        P Q P P            P A 
Sbjct: 700  LPQERSQQPLSAEGPHLSVPASVIVSAPP--------PAQDPAPAT----------PVAK 741

Query: 109  GTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPT 168
            G    P  P  Q++P   P      P K    +     P+Q     +  + S   +R P+
Sbjct: 742  GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801

Query: 169  PPIGRPTSTPTPPQQLPSQV---PEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPD 225
             P  RP S   PP + P      P+  P + G            +    +Q     P  +
Sbjct: 802  RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPG------------IFVIQNQLGVPPPASN 849

Query: 226  PVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSS 285
            P   +P P  +  L  + +  EG              PLPP+P    S   S +A+  SS
Sbjct: 850  PAPTAPGPP-QPPLRPQSQPPEG--------------PLPPAPHLPPSSTSSAVAS--SS 892

Query: 286  ALSSQPIFTTAIDDRCEL---SSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSV 342
              SS+    T  D + +      P +   P P+L    E + P P       +   P   
Sbjct: 893  ETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA 952

Query: 343  APNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECI 402
             P    L+   + +     +  K     +                     P     L  +
Sbjct: 953  LPQPKALLERFHQVPSGIILQNKAGGAPAA--------------------PQTSTSLGPL 992

Query: 403  PAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAAT 437
             +P     V      P   P +P H P   P AAT
Sbjct: 993  TSPAASVLVSG--QAPSGTPTAPSHAPAPAPMAAT 1025



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 113/554 (20%), Positives = 165/554 (29%), Gaps = 125/554 (22%)

Query: 9   SPFFQRPQIQPPRATIPNSSPSIRPGAQT-PTAVYQANQHIMMVNHLPMPYPVPQGPQYC 67
           +P  Q    + P AT   ++P   PGA + P +V+  NQ   +V  +P  + +P   Q+ 
Sbjct: 416 APALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIV--IPAQHMLPGQNQFL 473

Query: 68  IPQYRHSGPPYVGPPQQYPVQPPG----------------------------PGPFYPGP 99
           +P     G P V  PQQ    P                               GP   GP
Sbjct: 474 LP-----GAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGP 528

Query: 100 GPGDFPNAYGTPFYPSQPVYQSAPII-----------VPTQQQPPPAKREKKTI------ 142
                  A+      + P+    P +           +PTQ QP PA     T+      
Sbjct: 529 VLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL 588

Query: 143 ------RIRDPNQGGKDITEEIMSGGGSR----NPTPPIGRPTSTPTPP--QQLPSQVPE 190
                  +  P+   +  T    +G  +      P P      STP P   QQ  +Q P 
Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPP 648

Query: 191 HSPVVYGTVE-SAHLAASTPVTAASDQK----QEEKPKPDPVLKSPSPVLRLVLSGEKKE 245
            +P         A     +P  A+S +K    Q     P  +L   S  L++ L  E+ +
Sbjct: 649 QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDS--LQMFLPQERSQ 706

Query: 246 Q----EGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRC 301
           Q    EG      A V ++  P    P   + VA+     P +    + P     I    
Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA 766

Query: 302 ELSSPREDTIPI----------PSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVS 351
            L  P   + P           P L S   T  P         + + P     +  P   
Sbjct: 767 PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQ 826

Query: 352 STNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPE---------------- 395
           +   +  I  +  +L               P    L     PPE                
Sbjct: 827 APPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSS 886

Query: 396 -----EMKLECIPAP--------ITPSTVPSFPPTPP----------TPPASPPHTPVIV 432
                      +PAP          PS  P   PTPP           PP  PP T  +V
Sbjct: 887 AVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMV 946

Query: 433 PAAATTVSSPSAAI 446
                 +  P A +
Sbjct: 947 TTPFPALPQPKALL 960


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 120/498 (24%), Positives = 172/498 (34%), Gaps = 100/498 (20%)

Query: 15   PQIQPPRATIPN-SSPSIRPGA------QTPTAVYQANQHIMMVNHLPMPYPVPQG---- 63
            P   PP   +P+ S+PS    A       T T +  A+QH   +   P P PV Q     
Sbjct: 640  PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP-PVMQSQSVK 698

Query: 64   PQYCIPQYRHSGPPYVGPPQQYPVQPPGPGP----FYPGPGPGDFPNAYGTP----FYPS 115
            PQ  +P      P  V PP   P  PP PG       P P     P     P     +  
Sbjct: 699  PQILVP------PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752

Query: 116  QPVYQSAPIIVPTQQQPPPAKRE-------KKTIRIRDPNQGGKDITEEIMSGGGSRNPT 168
            Q + Q AP   PT   PPP           K  + I  P          +++      PT
Sbjct: 753  QHITQVAP---PTPPPPPPIPAPLPPQAPPKPLVTIPAPTS--TKTVAPVVTQAAPPTPT 807

Query: 169  PPIGR------------PTSTPTPPQQLPSQV----------PEHSPV--VYGTVESAHL 204
            PP+              P S PTPP  +P             P  SP+  V   V+    
Sbjct: 808  PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867

Query: 205  AASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPL 264
                P T  + + Q  KP P  V     P +       K + + Q S     + +     
Sbjct: 868  QFPPPPTPPAMESQPLKPVPANVAPQSPPAV-------KAKPKWQPSS----IPVPSPDF 916

Query: 265  PPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSD 324
            PP P   S V      +P  +     P   +   D+    SP + T    S TS      
Sbjct: 917  PPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS--GSPGKKT----SKTSSPGGKK 970

Query: 325  PLPTNENDDDICKKPCSVAPNDIPLVSSTN-LINEINGVSEKLSATESIVEIVKQEVLPL 383
            P PT + +  I  K  S A +  P   S + L+++    +E  S ++  +        P 
Sbjct: 971  PPPTPQRNSSI--KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG 1028

Query: 384  TLELEILENPPEEMKLECIPA--PI-------------TPSTVPSFPPTPPTPPASPPHT 428
             L L  + N P  ++  C+ A  P+             +P +   FPP PP      P  
Sbjct: 1029 KLNLSGV-NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP-- 1085

Query: 429  PVIVPAAATTVSSPSAAI 446
            P+ +PA  +  +SP  A+
Sbjct: 1086 PIEIPAVFSGNTSPKVAV 1103



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 88/384 (22%), Positives = 123/384 (32%), Gaps = 74/384 (19%)

Query: 77  PYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAK 136
           PY       P+ PP P P  P P P   P     P  PSQ          P+     P  
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPPPPPPPP-----PPLPSQSA--------PSAGSAAPMF 664

Query: 137 REKKTI-RIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTP----TPPQQLPSQVPEH 191
            +  TI R+++ +Q          SG   + PTPP+ +  S       PP  +    P  
Sbjct: 665 VKYSTITRLQNASQH---------SGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP 715

Query: 192 SPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTS 251
            P              TP +A +  K        P   +P P L++           Q  
Sbjct: 716 PP------------PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI----------HQVQ 753

Query: 252 ETTAIVSIAELPLPPSPTTVSSVARS----TIAAPTSSALSSQPIFTTAIDDRCELSSPR 307
             T +      P PP P  +   A      TI APTS+   + P+ T A         P 
Sbjct: 754 HITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA-PVVTQAAPPTPTPPVPP 812

Query: 308 EDTIP------IPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEING 361
               P      IP          P PT       C KP     + +P V        +  
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSV--------VKQ 864

Query: 362 VSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT- 420
           ++ +     +   +  Q + P+   +     P  + K +  P+ I P   P FPP PP  
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI-PVPSPDFPPPPPES 923

Query: 421 ----PPASPPHTPVIVPAAATTVS 440
               PP  P   P   P    T S
Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTAS 947



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 71/331 (21%), Positives = 115/331 (34%), Gaps = 40/331 (12%)

Query: 11   FFQRPQIQP--PRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV----PQGP 64
            F  +P   P  P  ++     S  P   TP A+       +  N  P   P     P+  
Sbjct: 846  FCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905

Query: 65   QYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPI 124
               IP      PP   PP+   V PP P    P P P   P A  TP     P  +++  
Sbjct: 906  PSSIPVPSPDFPP--PPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963

Query: 125  IVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQL 184
              P  ++PPP  +   +I+     +  +     + S      P    G P+    PP   
Sbjct: 964  SSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA 1023

Query: 185  ---PSQVPEHSPVVYGTVESAHLAASTPVTAA----------SDQKQEEKPKPDPVLKSP 231
               P ++      + G ++   ++A  PV +           S     + P P P  + P
Sbjct: 1024 PPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083

Query: 232  SPVLRL--VLSGEKKEQEGQTS---ETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSA 286
             P + +  V SG    +    +   +  + +S+ + P P  P       R+     T + 
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRP------KRNDSTRLTQAE 1137

Query: 287  LSSQPIFTTAIDDRCELSSPREDTIPIPSLT 317
            +S QP   T +        P+  T P  SL+
Sbjct: 1138 ISEQPTMATVV--------PQVPTSPKSSLS 1160



 Score = 40.4 bits (93), Expect = 0.014
 Identities = 74/301 (24%), Positives = 99/301 (32%), Gaps = 59/301 (19%)

Query: 167 PTPPIGRPTSTPTPPQQLPSQVPEHSP------VVYGTVESAHLAAS------TPVTAAS 214
           P PP   P   P PP  LPSQ    +       V Y T+     A+        P T   
Sbjct: 632 PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPV 691

Query: 215 DQKQEEKPK----PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTT 270
            Q Q  KP+    P+ V+  P P       G       Q        S+ +   PP P  
Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAM---AQLKPAPCAPSLPQFSAPPPPLK 748

Query: 271 VSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNE 330
           +  V   T  AP +      P     I       +P +  + IP+ TS T+T  P+ T  
Sbjct: 749 IHQVQHITQVAPPT------PPPPPPIPAPLPPQAPPKPLVTIPAPTS-TKTVAPVVTQ- 800

Query: 331 NDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEIL 390
                     +  P   P V            ++K  A  +          P+ +    L
Sbjct: 801 ----------AAPPTPTPPVPP----------AKKQPAFPASYIPPSPPTPPVPVPPPTL 840

Query: 391 ENPPEEMKLECIPAPITPSTVPS--------FPPTPPTPPASPPHTPVIVPAAATTVSSP 442
              P++      P P   S VPS        FPP PPTPPA        VPA     S P
Sbjct: 841 ---PKQQSFCAKPPPSPLSPVPSVVKQIASQFPP-PPTPPAMESQPLKPVPANVAPQSPP 896

Query: 443 S 443
           +
Sbjct: 897 A 897



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 36/117 (30%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 345 NDIPLVSSTNLINEINGVSEKLSA----TESIVEIVKQEVLPLTLELE--------ILEN 392
           + IP   S +     +GVS+   A    ++SIV  V  E      +LE         +  
Sbjct: 541 SSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNR 600

Query: 393 PPEEMKLECIPAP--ITPSTV--PSFP-PTPPTPPASPPHTPVIVPAAATTVSSPSA 444
           P   +     P P  +TP T   PS P P PP PP  PP  P   P    + S+PSA
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657



 Score = 31.6 bits (70), Expect = 6.4
 Identities = 40/133 (30%), Positives = 54/133 (40%), Gaps = 19/133 (14%)

Query: 393 PPEEMKLECIPAPITPSTVP-----SFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAIT 447
           PP+   L  IPAP +  TV      + PPTP TPP  P       PA+    S P+  + 
Sbjct: 778 PPKP--LVTIPAPTSTKTVAPVVTQAAPPTP-TPPVPPAKKQPAFPASYIPPSPPTPPVP 834

Query: 448 V-QRVLEEDESI-----RTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQI 501
           V    L + +S       + LS     ++          T   ++SQ L     PVPA +
Sbjct: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPL----KPVPANV 890

Query: 502 AITVPKTWK-KPK 513
           A   P   K KPK
Sbjct: 891 APQSPPAVKAKPK 903


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 101/457 (22%), Positives = 163/457 (35%), Gaps = 99/457 (21%)

Query: 3   SQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQ 62
           S PQ R P      IQP      + S S  PGA  P A  +A           +P PV Q
Sbjct: 449 SPPQPRHP------IQPSLPGTTSGSLSSVPGAPAPPAASKAPV---------VPSPVLQ 493

Query: 63  GPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA 122
            P   +          +G     P+ P   G  +P P P       G  F    P    A
Sbjct: 494 SPSEGLG---------MGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF----PGMLGA 540

Query: 123 PIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQ 182
             +  +  QPPP+     ++               +++GGG + P  P+  P   P PP 
Sbjct: 541 LPLPLSLGQPPPSPLLNHSLF-------------GVLTGGGGQPPPEPLLPPPGGPGPP- 586

Query: 183 QLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS-- 240
            L    PE   +         L AS      SD        P  +L S  P+L L  +  
Sbjct: 587 -LAPGEPEGPSL---------LVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAG 636

Query: 241 ---GEKKEQEGQTSET-TAIVSIAELPLPP--SPTTVSSVARSTIAAPTSSALSSQPIFT 294
              G  +   G + E  + +  ++ L  PP  +P T+ ++  + +AA       + P   
Sbjct: 637 DGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPP--- 693

Query: 295 TAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA--PNDIPLVSS 352
                 C LS+P+      P+ +  T T+DP         + K P +    P  +  +  
Sbjct: 694 ----QPCVLSAPQPGP---PTSSVTTATTDP-----GASSLGKAPSNSGRPPQLLSPLLG 741

Query: 353 TNLINEINGVSEKLSATESIVEI----------------------VKQEVLPLTLELEIL 390
            +L+ +++ ++    A  S+++                       + +   PL   L+ L
Sbjct: 742 ASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSL 801

Query: 391 ENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPH 427
           + PPE+ +  C+P     S +   P  PP    +PPH
Sbjct: 802 QIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838



 Score = 37.7 bits (86), Expect = 0.089
 Identities = 65/277 (23%), Positives = 92/277 (33%), Gaps = 77/277 (27%)

Query: 2   NSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMV---------- 51
           +S P +  P F       P    P+++    PG  +   V  A  H+ +V          
Sbjct: 251 SSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTV 310

Query: 52  --------------------NHLPMPYP-VPQG--PQYCIPQYRHSGPPYVGPPQQYPVQ 88
                                H P+P P   QG  P+   P   HS    + P Q+ P +
Sbjct: 311 EGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSS--LRPSQRRPRR 368

Query: 89  PP-------GPGPFYP----GPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKR 137
           PP       G GP  P       P   P  +  P  PSQP+    P ++     P P   
Sbjct: 369 PPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLP-EPSQPI---LPSVLSLLGLPTPG-- 422

Query: 138 EKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEH--SPVV 195
                    P+          + G  +  P PP     S+ +PPQ      P H   P +
Sbjct: 423 ---------PSHSDGSFN---LLGSDAHLPPPP---TLSSGSPPQ------PRHPIQPSL 461

Query: 196 YGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPS 232
            GT   +   +S P   A     +    P PVL+SPS
Sbjct: 462 PGTTSGS--LSSVPGAPAPPAASKAPVVPSPVLQSPS 496



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 62/253 (24%), Positives = 88/253 (34%), Gaps = 58/253 (22%)

Query: 69  PQYRHS---GPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPII 125
           PQ  H+   GPP   PP + P   P  G      GPG  P     P  PS  V Q+ P +
Sbjct: 132 PQMFHTVSPGPPSARPPCRVPPTTPLNG------GPGSLP-----PEPPS--VSQAFPTL 178

Query: 126 VPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGR------------ 173
                  PP        R+ DP   G   +   +  G + +P PP               
Sbjct: 179 AGPGGLFPP--------RLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWG 230

Query: 174 --------PTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPD 225
                   P+   +PP    S  P   P ++     +      P+  +++      P   
Sbjct: 231 AALRSSLVPSDLGSPPAPHASSSPPSDPPLF---HCSDALTPPPLPPSNNLPAHPGPASQ 287

Query: 226 PVLKSPSPVLRLVLS--GEKKEQEG-------QTSETTAIVSIAELPLPPSPTTVSSVAR 276
           P + S +  L LVL   G     EG        +S  +A       PLPP P+T+    R
Sbjct: 288 PPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPP-PSTLQG-RR 345

Query: 277 STIAAPTSSALSS 289
               AP++S  SS
Sbjct: 346 PRAQAPSASHSSS 358


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 86/347 (24%), Positives = 125/347 (36%), Gaps = 49/347 (14%)

Query: 114  PSQPVYQSAPIIVPTQQ-----QPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPT 168
            P +P   +    +PT++     + P    EK TI    P      I+ E         PT
Sbjct: 714  PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPT-----ISPE--------KPT 760

Query: 169  PPIGRPTSTP---TPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPD 225
             P  +PT +P   T P + P+ +P   P +    E   ++   P T   +     +    
Sbjct: 761  TPTEKPTISPEKLTIPTEKPT-IPTEKPTI--PTEKPTISTEEPTTPTEETTISTEKPSI 817

Query: 226  PVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSS 285
            P+ K   P            +E  TS     +S  +L +P    T+S+  + TI  PT  
Sbjct: 818  PMEKPTLPT-----------EETTTSVEETTISTEKLTIPMEKPTIST-EKPTI--PTEK 863

Query: 286  ALSSQPIFTTAIDDRCELSSPRED-TIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAP 344
               S    T   +   +L+ P E  TIPI   T  TE    +PT +      K   S   
Sbjct: 864  PTISPEKLTIPTE---KLTIPTEKPTIPIEETTISTEKLT-IPTEKPTISPEKPTISTEK 919

Query: 345  NDIPLVSSTNLINEINGVSEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLECIP 403
              IP    T    E    +EKL+  TE     +  E L +  E   +      +  E + 
Sbjct: 920  PTIPTEKPTIPTEETTISTEKLTIPTEK--PTISPEKLTIPTEKPTISTEKPTIPTEKLT 977

Query: 404  APITPSTVPSFPPTPPTPP---ASPPHTPVIVPAAATTVSSPSAAIT 447
             P    T+P+  PT PT       PPH        A  V SP A  T
Sbjct: 978  IPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPST 1024



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 91/426 (21%), Positives = 155/426 (36%), Gaps = 48/426 (11%)

Query: 101  PGDFPNAYGT-PFYPSQ-PVYQSAPIIVPTQQQPPPAKR-----EKKTIRIRDPNQGGKD 153
            P + PN     P  PS+ P   +    +P+++   P+++     EK T+   +P    ++
Sbjct: 608  PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667

Query: 154  ITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAA 213
             T  +          P I  PT  P+ P + PS +P   P +  ++E   ++   P  + 
Sbjct: 668  TTTSMEE--------PVI--PTEKPSIPTEKPS-IPTEKPTI--SMEETIISTEKPTISP 714

Query: 214  SDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQ--EGQTSETTAIVSIAELPLPPSPTTV 271
                  EKP   P  K   P  +  +S EK     E  T  T       E P  P+    
Sbjct: 715  ------EKPTI-PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT 767

Query: 272  SSVARSTIAAPTSSALSSQPIFTTAIDDRC--ELSSPREDTIPIPSLTSCTETSDPLPTN 329
             S  + TI     +  + +P   T        E ++P E+T       S       LPT 
Sbjct: 768  ISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTE 827

Query: 330  ENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEI 389
            E    + +   S     IP+   T    +    +EK + +   + I  ++   LT+  E 
Sbjct: 828  ETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK---LTIPTEK 884

Query: 390  LENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPV---IVPAAATTVSSPSAAI 446
               P EE  +      I P+  P+  P  PT     P  P     +P   TT+S+    I
Sbjct: 885  PTIPIEETTISTEKLTI-PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTI 943

Query: 447  TVQRVLEEDESIR------TCLSEDAKEIQNKIEVEADGQT----EEILDSQNLNSRRSP 496
              ++     E +       T  +E       K+ +  +  T    +  + ++ L + R P
Sbjct: 944  PTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPP 1003

Query: 497  VPAQIA 502
             P+  A
Sbjct: 1004 HPSPTA 1009



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 79/367 (21%), Positives = 117/367 (31%), Gaps = 65/367 (17%)

Query: 101 PGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMS 160
           PG  P        P  PV  + P       + P    +K T+ I  P+   +  T     
Sbjct: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP--- 587

Query: 161 GGGSRNPTPPIGRPTST---PTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQK 217
                 PT P  +PT +   PT P + P+ +P   P +    E   +    P        
Sbjct: 588 ---KEKPTIPTEKPTISTEKPTIPSEKPN-MPSEKPTIPS--EKPTILTEKPTI------ 635

Query: 218 QEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARS 277
               P   P + S  P +    S EK     +   T    +   +  P  PT   S+   
Sbjct: 636 ----PSEKPTIPSEKPTI----STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687

Query: 278 TIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICK 337
             + PT     S     T I       SP + TIP    T  TE S   P  E      +
Sbjct: 688 KPSIPTEKPTISME--ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISP--EKPTTPTE 743

Query: 338 KPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEM 397
           KP    P + P +S            +  + TE      K  + P               
Sbjct: 744 KP--TIPTEKPTISP----------EKPTTPTE------KPTISP--------------- 770

Query: 398 KLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDES 457
             E +  P    T+P+  PT PT   +        P   TT+S+   +I +++     E 
Sbjct: 771 --EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEE 828

Query: 458 IRTCLSE 464
             T + E
Sbjct: 829 TTTSVEE 835


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,625,322
Number of Sequences: 37866
Number of extensions: 4065472
Number of successful extensions: 35440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 185
Number of HSP's successfully gapped in prelim test: 1096
Number of HSP's that attempted gapping in prelim test: 22078
Number of HSP's gapped (non-prelim): 9706
length of query: 1585
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1469
effective length of database: 13,855,062
effective search space: 20353086078
effective search space used: 20353086078
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.