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Search of human proteins with 187167261
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens]
(129 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens] 277 1e-75
gi|17530787 prokineticin 2 isoform b precursor [Homo sapiens] 223 4e-59
gi|14165282 prokineticin 1 [Homo sapiens] 108 9e-25
gi|7110719 dickkopf homolog 1 precursor [Homo sapiens] 38 0.003
gi|7657025 dickkopf homolog 4 precursor [Homo sapiens] 36 0.010
gi|7657023 dickkopf homolog 2 precursor [Homo sapiens] 34 0.037
gi|66346689 dickkopf homolog 3 precursor [Homo sapiens] 32 0.18
gi|40548393 dickkopf homolog 3 precursor [Homo sapiens] 32 0.18
gi|40548389 dickkopf homolog 3 precursor [Homo sapiens] 32 0.18
gi|11038659 ADAM metallopeptidase with thrombospondin type 1 mot... 30 0.40
gi|110825974 ADAM metallopeptidase with thrombospondin type 1 mo... 30 0.40
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 30 0.40
gi|167830411 natriuretic peptide receptor 1 [Homo sapiens] 29 1.2
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 28 1.5
gi|34304381 inversin isoform a [Homo sapiens] 28 1.5
gi|34304379 inversin isoform b [Homo sapiens] 28 1.5
gi|21450863 attractin isoform 2 [Homo sapiens] 28 2.0
gi|21450861 attractin isoform 1 [Homo sapiens] 28 2.0
gi|4505845 phospholipase A2, group X [Homo sapiens] 28 2.6
gi|10190748 CEGP1 protein [Homo sapiens] 27 4.5
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 27 4.5
gi|122937428 phospholipase A2, group 4E [Homo sapiens] 27 4.5
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 27 5.8
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 27 5.8
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 27 5.8
gi|28559039 mediator complex subunit 1 [Homo sapiens] 27 5.8
gi|67189007 mucin 1 isoform 2 precursor [Homo sapiens] 26 7.6
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 26 7.6
gi|113206028 mucin 1 isoform 7 precursor [Homo sapiens] 26 7.6
gi|4557635 orexin precursor [Homo sapiens] 26 7.6
>gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens]
Length = 129
Score = 277 bits (709), Expect = 1e-75
Identities = 129/129 (100%), Positives = 129/129 (100%)
Query: 1 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP 60
MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
Sbjct: 1 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP 60
Query: 61 MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF 120
MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF
Sbjct: 61 MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF 120
Query: 121 NRFICLAQK 129
NRFICLAQK
Sbjct: 121 NRFICLAQK 129
>gi|17530787 prokineticin 2 isoform b precursor [Homo sapiens]
Length = 108
Score = 223 bits (567), Expect = 4e-59
Identities = 108/129 (83%), Positives = 108/129 (83%), Gaps = 21/129 (16%)
Query: 1 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP 60
MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP
Sbjct: 1 MRSLCCAPLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTP 60
Query: 61 MGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSF 120
MGKLGDSCHPLTRK VPFFGRRMHHTCPCLPGLACLRTSF
Sbjct: 61 MGKLGDSCHPLTRK---------------------VPFFGRRMHHTCPCLPGLACLRTSF 99
Query: 121 NRFICLAQK 129
NRFICLAQK
Sbjct: 100 NRFICLAQK 108
>gi|14165282 prokineticin 1 [Homo sapiens]
Length = 105
Score = 108 bits (271), Expect = 9e-25
Identities = 48/108 (44%), Positives = 63/108 (58%), Gaps = 21/108 (19%)
Query: 18 LLLTPRAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNF 77
+LL D AVITGAC++D QCG G CCA+S+W++ +R+CTP+G+ G+ CHP + K
Sbjct: 10 MLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHK--- 66
Query: 78 GNGRQERRKRKRSKRKKEVPFFGRRMHHTCPCLPGLACLRTSFNRFIC 125
VPFF +R HHTCPCLP L C R R+ C
Sbjct: 67 ------------------VPFFRKRKHHTCPCLPNLLCSRFPDGRYRC 96
>gi|7110719 dickkopf homolog 1 precursor [Homo sapiens]
Length = 266
Score = 37.7 bits (86), Expect = 0.003
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFG 78
C + S C G+CCA W K IC P+ K G C RK + G
Sbjct: 189 CLRSSDCASGLCCARHFWSK---ICKPVLKEGQVCTKHRRKGSHG 230
>gi|7657025 dickkopf homolog 4 precursor [Homo sapiens]
Length = 224
Score = 35.8 bits (81), Expect = 0.010
Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 24/83 (28%)
Query: 33 ACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFGNGRQERRKRKRSKR 92
+C + CG G+CCA W K IC P+ G C RR K + +
Sbjct: 144 SCLRTFDCGPGLCCARHFWTK---ICKPVLLEGQVC--------------SRRGHKDTAQ 186
Query: 93 KKEVPFFGRRMHHTCPCLPGLAC 115
E+ C C PGL C
Sbjct: 187 APEI-------FQRCDCGPGLLC 202
>gi|7657023 dickkopf homolog 2 precursor [Homo sapiens]
Length = 259
Score = 33.9 bits (76), Expect = 0.037
Identities = 22/82 (26%), Positives = 30/82 (36%), Gaps = 25/82 (30%)
Query: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFGNGRQERRKRKRSKRK 93
C + S C G CCA W K IC P+ G+ C ++RK+
Sbjct: 183 CLRSSDCIEGFCCARHFWTK---ICKPVLHQGEVC---------------TKQRKKGSH- 223
Query: 94 KEVPFFGRRMHHTCPCLPGLAC 115
G + C C GL+C
Sbjct: 224 ------GLEIFQRCDCAKGLSC 239
>gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 31.6 bits (70), Expect = 0.18
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCH 69
CD C G+CCA + +CTP+ G+ CH
Sbjct: 208 CDNQRDCQPGLCCAFQRGL-LFPVCTPLPVEGELCH 242
>gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 31.6 bits (70), Expect = 0.18
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCH 69
CD C G+CCA + +CTP+ G+ CH
Sbjct: 208 CDNQRDCQPGLCCAFQRGL-LFPVCTPLPVEGELCH 242
>gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 31.6 bits (70), Expect = 0.18
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCH 69
CD C G+CCA + +CTP+ G+ CH
Sbjct: 208 CDNQRDCQPGLCCAFQRGL-LFPVCTPLPVEGELCH 242
>gi|11038659 ADAM metallopeptidase with thrombospondin type 1
motif, 2 isoform 2 [Homo sapiens]
Length = 566
Score = 30.4 bits (67), Expect = 0.40
Identities = 16/21 (76%), Positives = 16/21 (76%)
Query: 2 RSLCCAPLLLLLLLPPLLLTP 22
R LC A LLLLLLLPP LL P
Sbjct: 10 RLLCPALLLLLLLLPPPLLPP 30
Score = 26.9 bits (58), Expect = 4.5
Identities = 18/36 (50%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 2 RSLCCAPLLLLLLL--PPLLLTPRAGDAAVITGACD 35
R L C LLLLLLL PPLL P A + A D
Sbjct: 9 RRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAAD 44
>gi|110825974 ADAM metallopeptidase with thrombospondin type 1
motif, 2 isoform 1 preproprotein [Homo sapiens]
Length = 1211
Score = 30.4 bits (67), Expect = 0.40
Identities = 16/21 (76%), Positives = 16/21 (76%)
Query: 2 RSLCCAPLLLLLLLPPLLLTP 22
R LC A LLLLLLLPP LL P
Sbjct: 10 RLLCPALLLLLLLLPPPLLPP 30
Score = 26.9 bits (58), Expect = 4.5
Identities = 18/36 (50%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 2 RSLCCAPLLLLLLL--PPLLLTPRAGDAAVITGACD 35
R L C LLLLLLL PPLL P A + A D
Sbjct: 9 RRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAAD 44
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 30.4 bits (67), Expect = 0.40
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 8/51 (15%)
Query: 22 PRAGDAAVITGACDKDSQ----CGGGMCCAVSIWVKSIRICTPMGKLGDSC 68
P G+ AV TG C Q CGGG C S + S+ + G G SC
Sbjct: 456 PCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGV----GSCGSSC 502
>gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]
Length = 1061
Score = 28.9 bits (63), Expect = 1.2
Identities = 16/25 (64%), Positives = 17/25 (68%)
Query: 9 LLLLLLLPPLLLTPRAGDAAVITGA 33
LLLLLLLPPLLL R A +T A
Sbjct: 14 LLLLLLLPPLLLLLRGSHAGNLTVA 38
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 28.5 bits (62), Expect = 1.5
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 5/46 (10%)
Query: 29 VITGACDKDSQCGGGMCCAVSIWVKSIRICTP-----MGKLGDSCH 69
V+TG C S+ GG C S+ + C P G GD+C+
Sbjct: 1058 VVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACN 1103
>gi|34304381 inversin isoform a [Homo sapiens]
Length = 1065
Score = 28.5 bits (62), Expect = 1.5
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 10/48 (20%)
Query: 69 HPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTC-----PCLP 111
H RK+ R+E KRK ++++K GRR +C PCLP
Sbjct: 585 HEQLRKDAAAKKREEENKRKEAEQQK-----GRRSPDSCRPQALPCLP 627
>gi|34304379 inversin isoform b [Homo sapiens]
Length = 895
Score = 28.5 bits (62), Expect = 1.5
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 10/48 (20%)
Query: 69 HPLTRKNNFGNGRQERRKRKRSKRKKEVPFFGRRMHHTC-----PCLP 111
H RK+ R+E KRK ++++K GRR +C PCLP
Sbjct: 585 HEQLRKDAAAKKREEENKRKEAEQQK-----GRRSPDSCRPQALPCLP 627
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 28.1 bits (61), Expect = 2.0
Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 19/63 (30%)
Query: 9 LLLLLLLPPLLL------TPRAGDAAVITGA-------CDKDSQCGG------GMCCAVS 49
LLLLLL PPLLL A AA ++G+ CD+ GG G C +
Sbjct: 63 LLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPA 122
Query: 50 IWV 52
WV
Sbjct: 123 GWV 125
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 28.1 bits (61), Expect = 2.0
Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 19/63 (30%)
Query: 9 LLLLLLLPPLLL------TPRAGDAAVITGA-------CDKDSQCGG------GMCCAVS 49
LLLLLL PPLLL A AA ++G+ CD+ GG G C +
Sbjct: 63 LLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPA 122
Query: 50 IWV 52
WV
Sbjct: 123 GWV 125
>gi|4505845 phospholipase A2, group X [Homo sapiens]
Length = 165
Score = 27.7 bits (60), Expect = 2.6
Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
Query: 6 CAPLLLLLLLPPLLLT-----PRAGDAAVI 30
C P++LLLLLP LLL P +G+A+ I
Sbjct: 7 CLPIMLLLLLPSLLLLLLLPGPGSGEASRI 36
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 26.9 bits (58), Expect = 4.5
Identities = 20/43 (46%), Positives = 23/43 (53%), Gaps = 8/43 (18%)
Query: 7 APLLLLLLLPPLLL-----TPRAGDAAVITGACDKDSQCGGGM 44
A LLLLLLLPPLLL P G AA G + +C G+
Sbjct: 14 AVLLLLLLLPPLLLLAGAVPPGRGRAA---GPQEDVDECAQGL 53
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 26.9 bits (58), Expect = 4.5
Identities = 12/21 (57%), Positives = 16/21 (76%)
Query: 82 QERRKRKRSKRKKEVPFFGRR 102
+ERRKRK+ K+K+E GRR
Sbjct: 92 KERRKRKKEKKKRERKQRGRR 112
>gi|122937428 phospholipase A2, group 4E [Homo sapiens]
Length = 839
Score = 26.9 bits (58), Expect = 4.5
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 7/45 (15%)
Query: 82 QERRKRKRSKRKKEVPFFGRRMHHT-----C--PCLPGLACLRTS 119
Q RR+RKR K K + +T C PC P AC +T+
Sbjct: 186 QSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTA 230
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 26.6 bits (57), Expect = 5.8
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 81 RQERRKRKRSKRKKEVPFFGRRMHHTCP 108
RQ+ K KR K++KE G+R H + P
Sbjct: 643 RQKLEKDKRRKKRKEKEKKGKRRHSSLP 670
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 26.6 bits (57), Expect = 5.8
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 81 RQERRKRKRSKRKKEVPFFGRRMHHTCP 108
RQ+ K KR K++KE G+R H + P
Sbjct: 734 RQKLEKDKRRKKRKEKEKKGKRRHSSLP 761
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 26.6 bits (57), Expect = 5.8
Identities = 9/22 (40%), Positives = 17/22 (77%)
Query: 74 KNNFGNGRQERRKRKRSKRKKE 95
+N+ ++E++K+KRSK KK+
Sbjct: 631 RNSLDGSQEEKKKKKRSKAKKD 652
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 26.6 bits (57), Expect = 5.8
Identities = 11/34 (32%), Positives = 18/34 (52%)
Query: 67 SCHPLTRKNNFGNGRQERRKRKRSKRKKEVPFFG 100
S HP++ K+N G + ++ K K K +V G
Sbjct: 1336 SSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSG 1369
>gi|67189007 mucin 1 isoform 2 precursor [Homo sapiens]
Length = 264
Score = 26.2 bits (56), Expect = 7.6
Identities = 15/36 (41%), Positives = 18/36 (50%)
Query: 7 APLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGG 42
+P LLLLL L T A V+TG+ S GG
Sbjct: 7 SPFFLLLLLTVLTATTAPKPATVVTGSGHASSTPGG 42
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 26.2 bits (56), Expect = 7.6
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 25 GDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICT--PMGKLGDSC 68
GD+ T + + C GG CAV K + +CT P G G C
Sbjct: 760 GDSTAGTSSDCQPCPCPGGSSCAVVPKTKEV-VCTNCPTGTTGKRC 804
>gi|113206028 mucin 1 isoform 7 precursor [Homo sapiens]
Length = 159
Score = 26.2 bits (56), Expect = 7.6
Identities = 15/36 (41%), Positives = 18/36 (50%)
Query: 7 APLLLLLLLPPLLLTPRAGDAAVITGACDKDSQCGG 42
+P LLLLL L T A V+TG+ S GG
Sbjct: 7 SPFFLLLLLTVLTATTAPKPATVVTGSGHASSTPGG 42
>gi|4557635 orexin precursor [Homo sapiens]
Length = 131
Score = 26.2 bits (56), Expect = 7.6
Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Query: 9 LLLLLLLPPLLLTPRAGDAAVITGACDKDSQC 40
LLLLLLLPP LL+ +G AA C + C
Sbjct: 16 LLLLLLLPPALLS--SGAAAQPLPDCCRQKTC 45
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.142 0.483
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,764,793
Number of Sequences: 37866
Number of extensions: 258536
Number of successful extensions: 1447
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1348
Number of HSP's gapped (non-prelim): 114
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.