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Search of human proteins with 18640754
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18640754 synaptonemal complex central element protein 1
isoform 1 [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219555716 synaptonemal complex central element protein 1 isof... 560 e-160
gi|18640754 synaptonemal complex central element protein 1 isofo... 560 e-160
gi|219555718 synaptonemal complex central element protein 1 isof... 533 e-152
gi|194018732 hypothetical protein LOC100130958 [Homo sapiens] 185 3e-47
gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-l... 61 1e-09
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 61 1e-09
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 61 1e-09
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 61 1e-09
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 61 1e-09
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 61 1e-09
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 61 1e-09
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 61 1e-09
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 61 1e-09
gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l... 60 3e-09
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein... 60 3e-09
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l... 59 4e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 59 4e-09
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l... 59 5e-09
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l... 58 8e-09
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein... 58 8e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 57 1e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 57 1e-08
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 57 2e-08
gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-l... 57 2e-08
gi|42794779 myosin 18A isoform b [Homo sapiens] 57 2e-08
gi|28416946 myosin 18A isoform a [Homo sapiens] 57 2e-08
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 56 4e-08
gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-l... 55 5e-08
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 55 5e-08
gi|239745087 PREDICTED: similar to Golgin subfamily A member 8-l... 55 7e-08
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 560 bits (1442), Expect = e-160
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV
Sbjct: 37 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 96
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL
Sbjct: 97 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 156
Query: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL
Sbjct: 157 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 216
Query: 181 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 240
CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ
Sbjct: 217 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 276
Query: 241 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS 282
RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS
Sbjct: 277 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS 318
>gi|18640754 synaptonemal complex central element protein 1 isoform
1 [Homo sapiens]
Length = 282
Score = 560 bits (1442), Expect = e-160
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV
Sbjct: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL
Sbjct: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
Query: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL
Sbjct: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
Query: 181 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 240
CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ
Sbjct: 181 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 240
Query: 241 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS 282
RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS
Sbjct: 241 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVTWWS 282
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 533 bits (1374), Expect = e-152
Identities = 273/275 (99%), Positives = 274/275 (99%), Gaps = 1/275 (0%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV
Sbjct: 37 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 96
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL
Sbjct: 97 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 156
Query: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL
Sbjct: 157 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 216
Query: 181 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 240
CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ
Sbjct: 217 CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 276
Query: 241 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVA-PRP 274
RLKEELEKHGMQVPAQAQSTQEEEAGPGDVA P+P
Sbjct: 277 RLKEELEKHGMQVPAQAQSTQEEEAGPGDVASPKP 311
>gi|194018732 hypothetical protein LOC100130958 [Homo sapiens]
Length = 242
Score = 185 bits (470), Expect = 3e-47
Identities = 110/229 (48%), Positives = 146/229 (63%), Gaps = 38/229 (16%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+ MV KLQK GSLEP++E LI+RIN++QQAKKK++++L E ++ EAL +ELDSL+GEKV
Sbjct: 32 LAMVIKLQKEGSLEPQIEDLISRINDLQQAKKKSSEELRETHSLWEALHRELDSLNGEKV 91
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
HL+E+L KKQE LRIL++HCQEKESEA R L
Sbjct: 92 HLEEVLGKKQEALRILQMHCQEKESEAQR------------------------------L 121
Query: 121 AFEEQLEDLMGQHKDLWDFHMPE-RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCS 179
QLEDLMGQHKDLW+FHM E RLA+EI AL+ SKEQLL E +LV+A L +V+ +L S
Sbjct: 122 DVRGQLEDLMGQHKDLWEFHMLEQRLAREIRALERSKEQLLSERRLVRAKLREVERRLHS 181
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQL 228
EG +++GL A +++F E+ R A E+ A + +L
Sbjct: 182 PPEVEGAMAVNDGL-------KAELEIFGEQVRSAPEVGAGEGEAGPEL 223
>gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 601
Score = 60.8 bits (146), Expect = 1e-09
Identities = 70/339 (20%), Positives = 135/339 (39%), Gaps = 69/339 (20%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLY 149
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 94
H+K L +K + L + H +++ E R L
Sbjct: 150 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 209
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE----------------------- 191
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKK 327
Query: 192 --GLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ------------- 236
+ L +Q +Q +E RK EE + ++H+ LQQ + Q
Sbjct: 328 NQRISLLNQRQEERIQEQEERLRKQEERIQ---EQHKSLQQLAKPQSVFEEPNNENKNAL 384
Query: 237 QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 275
Q Q++KE EK G + + +E EA G AP PG
Sbjct: 385 QLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG 423
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2373
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2374 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2422
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2478
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2479 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2533
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2534 QQRQQ--QQMEQERQRLVASMEE 2554
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2373 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2424
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2473
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2474 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2521
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2522 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2581
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2582 QQEELLAEENQR 2593
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1526 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1583
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1640
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1641 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1686
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1687 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1746
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1747 TQKRQELEA 1755
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 1988 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 2021
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2081
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2082 EAEAARRAAEEAEEARVQAEREA 2104
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1587 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1646
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1647 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1706
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1765
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1766 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1822
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1823 DAARQRAEAERVLAE 1837
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1358 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1413
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1414 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1468
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1469 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1508
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1509 RKRQAEVEL---ASRVKAEAEAAREKQ 1532
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2031
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2032 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2087
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2088 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2146
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2147 ARRAQAEQAALRQKQAADAEMEKH 2170
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2110 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2163
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2164 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2221
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2222 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2280 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2336
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2337 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1228 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1284
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1285 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1340
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1397
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEE 1421
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2318 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2377
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2378 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2426
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2427 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2482
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2483 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2537
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2538 QQRQQ--QQMEQERQRLVASMEE 2558
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2377 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2428
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2429 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2477
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2478 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2525
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2526 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2585
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2586 QQEELLAEENQR 2597
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1530 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1587
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1588 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1644
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1645 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1690
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1691 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1750
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1751 TQKRQELEA 1759
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1877 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1931
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1932 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1991
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 1992 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 2025
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2026 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2085
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2086 EAEAARRAAEEAEEARVQAEREA 2108
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1591 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1650
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1651 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1710
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1711 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1769
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1770 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1826
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1827 DAARQRAEAERVLAE 1841
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1362 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1417
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1418 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1472
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1473 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1512
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1513 RKRQAEVEL---ASRVKAEAEAAREKQ 1536
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1921 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1980
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 1981 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2035
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2036 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2091
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2092 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2150
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2151 ARRAQAEQAALRQKQAADAEMEKH 2174
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2114 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2167
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2168 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2225
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2226 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2283
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2284 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2340
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2341 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2375
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1232 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1288
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1289 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1344
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1345 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1401
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1402 QEEVVRREEAAVDAQQQKRSIQEE 1425
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2314 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2373
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2374 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2422
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2478
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2479 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2533
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2534 QQRQQ--QQMEQERQRLVASMEE 2554
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2373 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2424
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2473
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2474 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2521
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2522 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2581
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2582 QQEELLAEENQR 2593
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1526 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1583
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1640
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1641 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1686
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1687 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1746
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1747 TQKRQELEA 1755
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 1988 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 2021
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2081
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2082 EAEAARRAAEEAEEARVQAEREA 2104
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1587 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1646
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1647 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1706
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1765
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1766 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1822
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1823 DAARQRAEAERVLAE 1837
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1358 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1413
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1414 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1468
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1469 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1508
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1509 RKRQAEVEL---ASRVKAEAEAAREKQ 1532
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2031
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2032 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2087
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2088 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2146
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2147 ARRAQAEQAALRQKQAADAEMEKH 2170
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2110 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2163
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2164 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2221
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2222 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2280 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2336
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2337 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1228 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1284
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1285 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1340
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1397
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEE 1421
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2282 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2341
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2342 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2390
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2391 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2446
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2447 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2501
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2502 QQRQQ--QQMEQERQRLVASMEE 2522
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2341 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2392
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2393 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2441
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2442 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2489
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2490 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2549
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2550 QQEELLAEENQR 2561
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1494 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1551
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1552 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1608
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1609 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1654
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1655 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1714
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1715 TQKRQELEA 1723
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1841 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1895
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1896 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1955
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 1956 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 1989
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 1990 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2049
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2050 EAEAARRAAEEAEEARVQAEREA 2072
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1555 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1614
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1615 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1674
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1675 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1733
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1734 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1790
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1791 DAARQRAEAERVLAE 1805
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1326 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1381
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1382 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1436
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1437 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1476
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1477 RKRQAEVEL---ASRVKAEAEAAREKQ 1500
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1885 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1944
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 1945 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 1999
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2000 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2055
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2056 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2114
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2115 ARRAQAEQAALRQKQAADAEMEKH 2138
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2078 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2131
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2132 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2189
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2190 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2247
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2248 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2304
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2305 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2339
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1196 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1252
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1253 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1308
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1309 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1365
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1366 QEEVVRREEAAVDAQQQKRSIQEE 1389
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2451 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2510
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2511 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2559
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2560 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2615
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2616 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2670
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2671 QQRQQ--QQMEQERQRLVASMEE 2691
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2510 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2561
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2562 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2610
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2611 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2658
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2659 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2718
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2719 QQEELLAEENQR 2730
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1663 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1720
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1777
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1778 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1823
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1824 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1883
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1884 TQKRQELEA 1892
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 2010 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 2064
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 2065 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2124
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 2125 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 2158
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2159 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2218
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2219 EAEAARRAAEEAEEARVQAEREA 2241
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1724 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1783
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1784 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1843
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1844 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1902
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1903 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1959
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1960 DAARQRAEAERVLAE 1974
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1495 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1550
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1551 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1605
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1606 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1645
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1646 RKRQAEVEL---ASRVKAEAEAAREKQ 1669
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 2054 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 2113
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 2114 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2168
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2169 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2224
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2225 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2283
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2284 ARRAQAEQAALRQKQAADAEMEKH 2307
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2247 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2300
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2301 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2358
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2359 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2416
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2417 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2473
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2474 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2508
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1365 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1421
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1422 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1477
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1478 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1534
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1535 QEEVVRREEAAVDAQQQKRSIQEE 1558
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2292 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2351
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2352 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2400
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2401 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2456
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2457 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2511
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2512 QQRQQ--QQMEQERQRLVASMEE 2532
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2351 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2402
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2403 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2451
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2452 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2499
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2500 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2559
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2560 QQEELLAEENQR 2571
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1504 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1561
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1562 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1618
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1619 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1664
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1665 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1724
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1725 TQKRQELEA 1733
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1851 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1905
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1906 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1965
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 1966 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 1999
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2000 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2059
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2060 EAEAARRAAEEAEEARVQAEREA 2082
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1565 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1624
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1625 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1684
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1685 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1743
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1744 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1800
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1801 DAARQRAEAERVLAE 1815
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1336 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1391
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1392 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1446
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1447 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1486
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1487 RKRQAEVEL---ASRVKAEAEAAREKQ 1510
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1895 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1954
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 1955 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2009
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2010 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2065
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2066 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2124
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2125 ARRAQAEQAALRQKQAADAEMEKH 2148
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2088 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2141
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2142 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2199
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2200 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2257
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2258 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2314
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2315 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2349
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1206 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1262
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1263 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1318
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1319 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1375
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1376 QEEVVRREEAAVDAQQQKRSIQEE 1399
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2300 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2359
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2360 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2408
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2409 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2464
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2465 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2519
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2520 QQRQQ--QQMEQERQRLVASMEE 2540
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2359 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2410
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2411 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2459
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2460 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2507
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2508 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2567
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2568 QQEELLAEENQR 2579
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1512 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1569
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1570 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1626
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1627 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1672
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1673 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1732
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1733 TQKRQELEA 1741
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1859 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1913
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1914 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1973
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 1974 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 2007
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2008 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2067
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2068 EAEAARRAAEEAEEARVQAEREA 2090
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1573 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1632
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1633 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1692
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1693 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1751
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1752 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1808
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1809 DAARQRAEAERVLAE 1823
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1344 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1399
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1400 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1454
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1455 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1494
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1495 RKRQAEVEL---ASRVKAEAEAAREKQ 1518
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1903 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1962
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 1963 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2017
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2018 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2073
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2074 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2132
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2133 ARRAQAEQAALRQKQAADAEMEKH 2156
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2096 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2149
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2150 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2207
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2208 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2265
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2266 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2322
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2323 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2357
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1214 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1270
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1271 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1326
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1327 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1383
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1384 QEEVVRREEAAVDAQQQKRSIQEE 1407
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 60.8 bits (146), Expect = 1e-09
Identities = 74/263 (28%), Positives = 120/263 (45%), Gaps = 38/263 (14%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGE-ARTICEALQKELDSLHGEKV 60
E +Q +Q+ L+ E+L + Q+ ++ +D + A+ + E Q +L E+
Sbjct: 2341 EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ 2400
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
E +S + E L++ + +E R +E +R Q EE K + L
Sbjct: 2401 RQLE-MSAEAERLKL-------RVAEMSRAQARAEEDAQRFRK---QAEEIGEKLHRTEL 2449
Query: 121 AFEEQLE-----DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK- 174
A +E++ ++ Q D H ERL + I L+ KE+L +E KL++ E+++
Sbjct: 2450 ATQEKVTLVQTLEIQRQQSD----HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQT 2505
Query: 175 ---HQLCSLCGAEGPSTLDE--GLFLRS----QEAAATVQLFQEEHRKAEELLAAAAQRH 225
QL A S L E L R QE A QLFQ+E KA++L +
Sbjct: 2506 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQL-----REE 2560
Query: 226 QQLQQKCQQQQQKRQRLKEELEK 248
QQ QQ QQ +Q+RQRL +E+
Sbjct: 2561 QQRQQ--QQMEQERQRLVASMEE 2581
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 42/252 (16%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
Q+ + E L R+ E+ +A+ +A +D R E + GEK+H E+ +
Sbjct: 2400 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI--------GEKLHRTELAT 2451
Query: 68 KKQETL-RILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQL 126
+++ TL + L + Q+ + +A R + E +E EK K +Q + +
Sbjct: 2452 QEKVTLVQTLEIQRQQSDHDAERLREAIAE-----------LEREKEKLQQEAKLLQLKS 2500
Query: 127 EDLMGQHKDLWDFHMPERLAKEICALDSS----KEQLLKEEKLV---KATLEDVKHQLCS 179
E++ + E+L +E AL S K+ LL+ E+ + KA LE QL
Sbjct: 2501 EEMQTVQQ--------EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE----QLFQ 2548
Query: 180 LCGAEGPSTLDEGLFLRSQ---EAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
A+ +E + Q E V +E R+ E ++ ++LQQ QQ++
Sbjct: 2549 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRR 2608
Query: 237 QKRQRLKEELEK 248
Q+ + L EE ++
Sbjct: 2609 QQEELLAEENQR 2620
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 28/249 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
E + K++A + L E R E ++ L E+ ++ + + R Q K +
Sbjct: 1553 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ--RSAEAELQSKRA 1610
Query: 86 EAHRKHTMLQEC--KERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPE 143
K L+ +E ++ L+ E E+ Q+Q A E+ + + + W E
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ---AEAERAREEAERELERWQLKANE 1667
Query: 144 RLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAAT 203
L + A E++ +++ L +A E K + G + ++A
Sbjct: 1668 ALRLRLQA-----EEVAQQKSLAQAEAEKQKEEAEREARRRGKA---------EEQAVRQ 1713
Query: 204 VQLFQEEHRKAEELLAAAAQRHQQLQQKC-------QQQQQKRQRLKEELEKHGMQVPAQ 256
+L ++E K +L AQ+ +Q+ +Q +Q+RQ L+EEL + + A
Sbjct: 1714 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1773
Query: 257 AQSTQEEEA 265
Q QE EA
Sbjct: 1774 TQKRQELEA 1782
Score = 41.2 bits (95), Expect = 0.001
Identities = 72/263 (27%), Positives = 116/263 (44%), Gaps = 46/263 (17%)
Query: 18 EVLINRINEVQQAKKKANKDLGEARTICEALQKELDS-LHGEKVHLKEIL-SKKQETLRI 75
E R E Q A+ KA+ + A+ L+K DS L +K +++ L ++Q I
Sbjct: 1900 EAFQRRRLEEQAAQHKADIEERLAQ-----LRKASDSELERQKGLVEDTLRQRRQVEEEI 1954
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISA---LNLQIEEEKNKQRQLRLAFEEQLEDLMGQ 132
L L +++ A + L+ + R +A L + + E RQ +LA EE+ +
Sbjct: 1955 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2014
Query: 133 HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEG 192
ER+ K + A + + Q KA LE+V+ + ++E
Sbjct: 2015 ----------ERVQKSLAAEEEAARQR-------KAALEEVERL---------KAKVEEA 2048
Query: 193 LFLRS---QEAAATVQLFQEEHRK---AEELLAAAA--QRHQQLQQKCQQQQQKRQRLKE 244
LR QE+A +QL QE +K AEE A A Q+ Q+LQQ QQ+Q +L+
Sbjct: 2049 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2108
Query: 245 ELE--KHGMQVPAQAQSTQEEEA 265
E E + + +A+ E EA
Sbjct: 2109 EAEAARRAAEEAEEARVQAEREA 2131
Score = 40.8 bits (94), Expect = 0.001
Identities = 54/255 (21%), Positives = 108/255 (42%), Gaps = 21/255 (8%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKE 64
+K LE ++ + ++++ ++ + EA E ++EL+ E + L+
Sbjct: 1614 EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRL 1673
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL------ 118
+ + + + ++++ EA R+ + +E+ E+E KQRQL
Sbjct: 1674 QAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQ 1733
Query: 119 -RLAFEEQLEDLMG------QHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
RLA E++L L Q + L + + RL +E A +++L E V+A +E
Sbjct: 1734 QRLAAEQELIRLRAETEQGEQQRQLLEEEL-ARLQREAAAATQKRQELEAELAKVRAEME 1792
Query: 172 DVKHQLCSLCGAEGPS-TLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQ 230
+ L S AE S + E R + A + EE + L A ++ Q ++
Sbjct: 1793 VL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1849
Query: 231 KCQQQQQKRQRLKEE 245
+Q+ + +R+ E
Sbjct: 1850 DAARQRAEAERVLAE 1864
Score = 38.5 bits (88), Expect = 0.007
Identities = 45/207 (21%), Positives = 102/207 (49%), Gaps = 32/207 (15%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
E+ L E+ + ++ ++ H Q K ++A R+ +E ++R+ ++ EE +Q
Sbjct: 1385 ERERLAEVEAALEKQRQLAEAHAQAK-AQAERE---AKELQQRMQEEVVRREEAAVDAQQ 1440
Query: 118 LRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQL 177
+ + +E+L+ L + + A++ A + S+ ++ +E ++V+ LE + Q
Sbjct: 1441 QKRSIQEELQQLRQSSEA-----EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQR 1495
Query: 178 CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQ 237
GAEG + L R++EA A + QEE ++L+++ Q + Q
Sbjct: 1496 G---GAEGEL---QALRARAEEAEAQKRQAQEE--------------AERLRRQVQDESQ 1535
Query: 238 KRQRLKEELEKHGMQVPAQAQSTQEEE 264
++++ + EL +V A+A++ +E++
Sbjct: 1536 RKRQAEVEL---ASRVKAEAEAAREKQ 1559
Score = 37.7 bits (86), Expect = 0.011
Identities = 56/264 (21%), Positives = 103/264 (39%), Gaps = 31/264 (11%)
Query: 7 LQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEAL-----QKELDSLHGEKVH 61
L++ +E + L + K + +LG R+ E Q EL++ ++
Sbjct: 1944 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 2003
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEE--------EKN 113
+E +++ R+ + E+E+ RK + E + L ++EE E+
Sbjct: 2004 AEEERRRREAEERVQKSLAAEEEAARQRKAAL-----EEVERLKAKVEEARRLRERAEQE 2058
Query: 114 KQRQLRLAFEEQLEDLMGQHK------DLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
RQL+LA E + L + K + + + L +E LD QL E + +
Sbjct: 2059 SARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLD----QLRGEAEAAR 2114
Query: 168 ATLEDVKHQLCSLC--GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRH 225
E+ + A+ ++E L+ Q A Q + AE+L A Q
Sbjct: 2115 RAAEEAEEARVQAEREAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKEAEQEA 2173
Query: 226 QQLQQKCQQQQQKRQRLKEELEKH 249
+ Q Q +++Q E+EKH
Sbjct: 2174 ARRAQAEQAALRQKQAADAEMEKH 2197
Score = 37.7 bits (86), Expect = 0.011
Identities = 57/275 (20%), Positives = 120/275 (43%), Gaps = 46/275 (16%)
Query: 23 RINEVQQAKKKANKDL---GEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLH 79
++ E ++ K+ A + +A+ E L+KE + + ++ ++++
Sbjct: 2137 QVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAA------ 2190
Query: 80 CQEKESEAHRK---HTMLQECK--ERISALNLQIEEEKNKQRQL---------------- 118
+ E E H+K T+ Q+ + + ++ L LQ+EE +++ L
Sbjct: 2191 --DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR 2248
Query: 119 -RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICAL-----DSSKEQLLKE-EKLVKATLE 171
R EE+L + Q ++L + R+ E AL D+++ L +E EK+ + E
Sbjct: 2249 QRSQVEEELFSVRVQMEEL--SKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2306
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEEL--LAAAAQRHQQLQ 229
+ + + A +E L +Q+ A ++ +E+ + +E L A A+ QQ +
Sbjct: 2307 AARLSVAAQEAARLRQLAEEDL---AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK 2363
Query: 230 QKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ Q+Q ++ Q KE++ + + Q T E E
Sbjct: 2364 ELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 30.8 bits (68), Expect = 1.4
Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
++QE ++ + L + E R+ L E ER ++EE + +Q A ++
Sbjct: 1255 RRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYEL 1311
Query: 128 DLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE--------EKLVKATLEDVKHQLCS 179
L+ L P + K + S E +++E +L T + +K +
Sbjct: 1312 QLVTYKAQLEPVASPAKKPK----VQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1367
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L E L E +E A V+ E+ R+ E A AQ Q +++ ++ QQ+
Sbjct: 1368 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAE---AHAQAKAQAEREAKELQQRM 1424
Query: 240 QRLKEELEKHGMQVPAQAQSTQEE 263
Q E+ + Q +S QEE
Sbjct: 1425 QEEVVRREEAAVDAQQQKRSIQEE 1448
>gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 [Homo sapiens]
Length = 602
Score = 59.7 bits (143), Expect = 3e-09
Identities = 70/339 (20%), Positives = 134/339 (39%), Gaps = 69/339 (20%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKGKLNTDLY 149
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 94
H+K L +K + L + H +++ E R L
Sbjct: 150 HMKRSLRYFEEKSKDLAVCLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 209
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQLKESFQQVQLERDECAEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE----------------------- 191
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKK 327
Query: 192 --GLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ------------- 236
+ L +Q +Q +E RK EE + ++H+ LQQ + Q
Sbjct: 328 NQRISLLNQRQEERIQEQEERLRKQEERIQ---EQHKSLQQLAKPQSVFEEPNNENKNAL 384
Query: 237 QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 275
Q Q++KE EK G + + +E EA G AP PG
Sbjct: 385 QLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG 423
>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 2 [Homo sapiens]
Length = 602
Score = 59.7 bits (143), Expect = 3e-09
Identities = 70/336 (20%), Positives = 133/336 (39%), Gaps = 63/336 (18%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLY 149
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 94
H+K L +K + L + H +++ E R L
Sbjct: 150 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 209
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE------------------GLFLR 196
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKN 327
Query: 197 SQEAAATVQLFQEEHRKAEELLAAAAQR----HQQLQQKCQQQQ-------------QKR 239
+Q + Q +E R+ EE L +R H+ LQQ + Q Q
Sbjct: 328 NQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLE 387
Query: 240 QRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 275
Q++KE EK G + + +E EA G AP PG
Sbjct: 388 QQVKELQEKLGEVKETETSAQKEPEAARGPGAPGPG 423
>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 630
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/288 (19%), Positives = 125/288 (43%), Gaps = 38/288 (13%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 91 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLY 150
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 94
H+K L +K + L + H +++ E R L
Sbjct: 151 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 210
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 211 EQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 268
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKA 214
K+Q ++ + ++ +L +K+Q+ E P+ E +Q ++E +
Sbjct: 269 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSE----------VELQHLRKELERV 318
Query: 215 EELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQE 262
L A +++Q++ Q+Q+++ Q +E L K ++ Q +S Q+
Sbjct: 319 AGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQ 366
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 59.3 bits (142), Expect = 4e-09
Identities = 51/260 (19%), Positives = 124/260 (47%), Gaps = 12/260 (4%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTIC--EALQKELDSLHGEKVHLKEI 65
+K L+ +++++ + +E+Q K+ + L A+ + + LQ E D L E +
Sbjct: 209 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 268
Query: 66 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQ 125
L + E + Q++E + R+ +QE +E+I +I E++ K R+ E+
Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK 328
Query: 126 LEDLMGQHKDLWDFHMPER-LAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAE 184
E + Q + +W+ R L +++ + +EQ K ++ K ++ + + + +
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 185 GPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKE 244
++ +R QE ++ QE+ EE + ++ + +++ Q+Q++K +R +E
Sbjct: 389 EEKIREQEEKIREQE-----EMMQEQ----EEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 245 ELEKHGMQVPAQAQSTQEEE 264
++ + ++ Q + +E+E
Sbjct: 440 KIREQEKKIREQEEKIREQE 459
Score = 52.8 bits (125), Expect = 3e-07
Identities = 43/263 (16%), Positives = 118/263 (44%), Gaps = 36/263 (13%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 61
+M ++ +K+ E +++ +I E ++ ++ + + E E ++++ + + ++
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEEK 345
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA 121
++E+ K E +I + +E E R+ QE + ++ +I E++ K R+
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 122 FEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLC 181
+EQ E + Q + +W+ E + ++ + +E++ ++EK ++ E ++ Q
Sbjct: 406 MQEQEEKMGEQEEKMWE--QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ----- 458
Query: 182 GAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQR 241
+E ++ EE + + + + K Q+Q++K +R
Sbjct: 459 --------------------------EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 242 LKEELEKHGMQVPAQAQSTQEEE 264
+E++ + ++ Q + +E+E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQE 515
Score = 37.0 bits (84), Expect = 0.019
Identities = 31/165 (18%), Positives = 81/165 (49%), Gaps = 16/165 (9%)
Query: 3 MVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHL 62
M ++ +K+G E E + + E+Q+ ++K + + R + ++++ EK+
Sbjct: 406 MQEQEEKMGEQE---EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ-----EEKIRE 457
Query: 63 KEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAF 122
+E + ++QE E+E + + +QE +E++ +I E++ K R+
Sbjct: 458 QEEMMQEQEE------KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 123 EEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
EQ E + Q + +W+ E++ ++ + +E++ ++E+ ++
Sbjct: 512 REQEEMMQEQEEKMWE--QEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Score = 35.8 bits (81), Expect = 0.043
Identities = 37/209 (17%), Positives = 90/209 (43%), Gaps = 25/209 (11%)
Query: 9 KVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSK 68
K+ E ++ +I E ++ ++ + +GE ++++ E +E + +
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ-------EEKMWEQEEEMQEQEEKMRR 436
Query: 69 KQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLED 128
++E +R +E+E + + M+QE +E++ E++ K + +EQ E
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG-------EQEGKMCEQEAKMQEQEEK 489
Query: 129 LMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPST 188
+ Q E++ ++ + +E++ ++E++++ E + Q +C E
Sbjct: 490 MRRQE---------EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 189 LDEGLFLRSQE--AAATVQLFQEEHRKAE 215
E R +E V+L Q+E + E
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 602
Score = 58.9 bits (141), Expect = 5e-09
Identities = 69/336 (20%), Positives = 133/336 (39%), Gaps = 63/336 (18%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 90 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQLQTLNIQKEELNTDLY 149
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAHR-----------------------KHTML 94
H+K L +K + L + H +++ E L
Sbjct: 150 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQLSSPSKAGTEWKL 209
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 210 EQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 267
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDE------------------GLFLR 196
K+Q ++ + ++ +L +K+Q+ E P+ E
Sbjct: 268 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKN 327
Query: 197 SQEAAATVQLFQEEHRKAEELLAAAAQR----HQQLQQKCQQQQ-------------QKR 239
+Q + Q +E R+ EE L +R H+ LQQ + Q Q
Sbjct: 328 NQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKSTLQLE 387
Query: 240 QRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPG 275
Q++KE EK G ++ + +E EA G AP PG
Sbjct: 388 QQVKELQEKLGEVKESETSAQKEPEAARGPAAPGPG 423
>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 58.2 bits (139), Expect = 8e-09
Identities = 56/288 (19%), Positives = 124/288 (43%), Gaps = 38/288 (13%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + L+ +
Sbjct: 91 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKGKLNTDLY 150
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 94
H+K L +K + L + H +++ E R L
Sbjct: 151 HMKRSLRYFEEKSKDLAVCLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 210
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 211 EQSMREEALLKVQLTQLKESFQQVQLERDECAEHLKGE-RARWQQRM-RKMSQEICTLKK 268
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKA 214
K+Q ++ + ++ +L +K+Q+ E P+ E +Q ++E +
Sbjct: 269 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSE----------VELQHLRKELERV 318
Query: 215 EELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQE 262
L A +++Q++ Q+Q+++ Q +E L K ++ Q +S Q+
Sbjct: 319 AGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQ 366
>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
[Homo sapiens]
Length = 580
Score = 58.2 bits (139), Expect = 8e-09
Identities = 61/260 (23%), Positives = 118/260 (45%), Gaps = 29/260 (11%)
Query: 17 VEVLINRINEVQQAKKKANKDLGEARTICEALQK-------ELDSLHGEKVHLKEILSKK 69
+ L N I ++Q KK+ L E + QK ++ +L+ +K L L
Sbjct: 93 ISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHM 152
Query: 70 QETLRILRLHCQEKESE-AHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEE-QLE 127
+ +LR + +EK + A R LQ E S L+ + +K K Q + +F++ QLE
Sbjct: 153 KRSLR----YFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQFKESFQQVQLE 208
Query: 128 -DLMGQH----KDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCG 182
D +H + W M ++++EIC L K+Q ++ + ++ +L +K+Q+
Sbjct: 209 RDEYSEHLKGERARWQQRM-RKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLP 267
Query: 183 AEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRL 242
E P+ E +Q ++E + L A + +Q++ Q+Q+++ +
Sbjct: 268 PEPPAVPSE----------VELQHLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQ 317
Query: 243 KEELEKHGMQVPAQAQSTQE 262
+E L K ++ Q +S Q+
Sbjct: 318 EERLRKQEERIQEQHKSLQQ 337
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 57.4 bits (137), Expect = 1e-08
Identities = 54/282 (19%), Positives = 134/282 (47%), Gaps = 21/282 (7%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 61
E +K+++ + E + R E+ K++ + E E +EL+ E+
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 62 LKEILSKKQETLRILRLHC-QEKESEAHRKHTMLQECKERISALNLQI--------EEEK 112
++E K+QE +I QE+E++ R+ ++E +E+I ++ E+EK
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Query: 113 NKQRQLRLAFEE--QLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATL 170
++ + R EE + E+ + + +++W E++ ++ + +E++ ++E+ ++
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIW--RQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 171 EDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHR--------KAEELLAAAA 222
E ++ Q + E E ++ ++ ++++EE R + EE +
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 223 QRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
++ + ++K ++Q++KRQ +E++ K ++ Q + QE+E
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Score = 54.7 bits (130), Expect = 9e-08
Identities = 49/259 (18%), Positives = 122/259 (47%), Gaps = 17/259 (6%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTIC--EALQKELDSLHGEKVHLKEI 65
+K L+ +++++ + +E+Q K+ + L A+ + + LQ E D L E +
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280
Query: 66 LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQ 125
L + E + Q++E + R+ +QE +E+I +I E++ K R EQ
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR-------EQ 333
Query: 126 LEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEG 185
E + Q + +W+ E++ ++ + +E++ ++E+++ E ++ Q E
Sbjct: 334 EEKMRRQEEMMWE--KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ------EEM 385
Query: 186 PSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEE 245
+E + ++ ++ ++E ++ EE ++ Q+ + K +Q++K + +E+
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 246 LEKHGMQVPAQAQSTQEEE 264
+ + ++ Q + E+E
Sbjct: 446 IREQEKKMWRQEEKIHEQE 464
Score = 43.9 bits (102), Expect = 2e-04
Identities = 53/273 (19%), Positives = 121/273 (44%), Gaps = 34/273 (12%)
Query: 5 QKLQKVGS-LEPRVEV--LINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 61
++LQ V + L+ +VE L NR+N+ Q+ K ++ + + E +Q++ + + ++
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE--KIQEWEEKIQEQEEKIREQEEK 329
Query: 62 LKE----------ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE 111
++E ++ +K+E +R EKE + R+ M+ E +E++ + E+
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 112 KNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLE 171
+ K R+L EQ E + Q + E +E + ++ ++E+ ++ E
Sbjct: 390 EEKIRELEEKMHEQ-EKIREQEEK----RQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 172 DVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQK 231
++ Q E R +E + +EE ++ E+ + Q++
Sbjct: 445 KIREQ--------------EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 232 CQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+Q++K +E++ K +V Q + +E+E
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/220 (18%), Positives = 105/220 (47%), Gaps = 20/220 (9%)
Query: 58 EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQ 117
EK+H +E + +++E ++H QE++ + QE K R ++ +EEK +++
Sbjct: 483 EKIHEQEEIWRQKE-----KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
Query: 118 LRLAFEEQL---EDLMGQHKDLWDFH----MPERLAKEICALDSSKEQLLKEEKLVKATL 170
++ +E++ E+ M + + +W+ +++ ++ + +E++ ++E+ ++
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 171 EDVKHQLCSLCGAEGPSTLDEGLF------LRSQEAAATVQLFQEEHRKAEELLAAAAQR 224
E + Q + E E +R QE Q +E ++ EE + ++
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ--EEMTQEQEEKMGEQEEK 655
Query: 225 HQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
+ ++K Q+Q++ R +E++ + ++ Q + +E+E
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Score = 35.0 bits (79), Expect = 0.074
Identities = 34/169 (20%), Positives = 81/169 (47%), Gaps = 14/169 (8%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEV----QQAKKKANKDLGEARTICEALQKELDSLHG 57
+M ++ +K+ E +V +I E Q+ ++K K + R E +Q++ + +
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 58 --EKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQ 115
EK+ +E ++++QE E+E + + +QE +E + +I E++ K
Sbjct: 631 QEEKIREQEEMTQEQEE------KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI 684
Query: 116 RQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEK 164
R+ EQ E + Q + +W+ E++ ++ + +E++ ++E+
Sbjct: 685 REQEEKIREQEEMMQEQEEKMWE--QEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 35.0 bits (79), Expect = 0.074
Identities = 21/141 (14%), Positives = 65/141 (46%)
Query: 8 QKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILS 67
+K+ E ++ +I E ++ ++ + + E + + ++++ + +E +
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 68 KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLE 127
+++ET+ +E+E + + ++E +E + ++ E++ K + +EQ E
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Query: 128 DLMGQHKDLWDFHMPERLAKE 148
+ Q + +W+ + R +E
Sbjct: 725 KMRRQEEKMWEQEVRLRQQEE 745
Score = 29.3 bits (64), Expect = 4.1
Identities = 55/241 (22%), Positives = 90/241 (37%), Gaps = 48/241 (19%)
Query: 31 KKKANKDLGEARTI---CEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEA 87
KKK N T C + + E + H + L+ L + T+RIL CQ+ E
Sbjct: 87 KKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILT--CQKTE--- 141
Query: 88 HRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAK 147
L + + ++ +QL E + DL+ + D W F A
Sbjct: 142 ----------------LQMALYYSQHAVKQL----EGEARDLISRLHDSWKFAGELEQAL 181
Query: 148 EICALDSSK-----EQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAA 202
A K E+L KE + +LE ++ + DE L ++ +
Sbjct: 182 SAVATQKKKADRYIEELTKERDAL--SLELYRNTIT-----------DEELKEKNAKLQE 228
Query: 203 TVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQE 262
+QL + E K+E L + + + K QQ+ Q + L K V A+ Q+ E
Sbjct: 229 KLQLVESE--KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 263 E 263
E
Sbjct: 287 E 287
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 57.4 bits (137), Expect = 1e-08
Identities = 49/250 (19%), Positives = 118/250 (47%), Gaps = 27/250 (10%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTIC----EALQKELDSLHG 57
+M ++ +++G E +++ ++ E ++ +K + +GE E +QK+ + +
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
Query: 58 EKVHLKEILS--KKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQ 115
++ ++E ++QE + + E+E + + ++E +E++ Q+ E++ +
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Query: 116 RQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKH 175
R+ +Q E + Q + +W+ E++ K+ + +EQ+ K+E+ V+ E ++
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWE--QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 176 QLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQ 235
Q +E +R QE Q+ ++E + E+ Q+ Q +Q+ Q
Sbjct: 378 Q-------------EEQ--MRKQEE----QMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418
Query: 236 QQKRQRLKEE 245
+QK Q K+E
Sbjct: 419 EQKEQMRKQE 428
Score = 42.0 bits (97), Expect = 6e-04
Identities = 39/256 (15%), Positives = 110/256 (42%), Gaps = 29/256 (11%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKES 85
+V++ + + + G+ R + ++ G+ +E + +++E ++ E+E
Sbjct: 172 QVREQEGQVREQEGQVRE----QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 86 EAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLW----DFHM 141
+ ++ + E +E++ Q+++++ + R+ EQ E + Q + +
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 142 PERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAA 201
E+ ++ + +EQ+ ++E+ ++ E ++ Q Q
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ-------------------EEQMGK 328
Query: 202 ATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ--RLKEELEKHGMQVPAQAQS 259
Q+++++ + E+ Q Q +Q+ Q Q+Q+ Q + +E++ K Q+ Q +
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 260 TQEEEAGPGDVAPRPG 275
+++E G+ + G
Sbjct: 389 MRKQEEQMGEQKEQMG 404
Score = 41.6 bits (96), Expect = 8e-04
Identities = 33/172 (19%), Positives = 83/172 (48%), Gaps = 9/172 (5%)
Query: 81 QEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFH 140
+E+E + + ++E + ++ Q+ E++ + + EQ E + Q + + +
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE-- 224
Query: 141 MPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 200
E++ K+ + +EQ+ K+E+ V+ E ++ Q + E E L+ +E
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE- 283
Query: 201 AATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQ 252
Q QEE +E ++ +Q++++ +Q +++ ++++E+ E+ G Q
Sbjct: 284 ----QTEQEEQTGEQE--EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
Score = 38.1 bits (87), Expect = 0.009
Identities = 44/270 (16%), Positives = 121/270 (44%), Gaps = 16/270 (5%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 61
E+ ++LQ V + + +++ I + + K G+ R ++++ + ++
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
Query: 62 LKEILSKKQET---LRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 118
++E + +E +R +E+E + + ++E + ++ Q+ E++ + R+
Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
Query: 119 RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLC 178
E Q+ + GQ ++ ++ ++ + + Q+ ++E V+ V+ Q
Sbjct: 135 ----EGQVREQEGQVRE-----QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 179 SLCGAEGPSTLDEGLFLRSQEAAAT----VQLFQEEHRKAEELLAAAAQRHQQLQQKCQQ 234
+ EG EG +E +Q +E+ + EE + ++ + +++ Q+
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 235 QQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
Q+++ Q+ +E++ K Q+ Q + +E+E
Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQE 275
Score = 35.0 bits (79), Expect = 0.074
Identities = 31/184 (16%), Positives = 80/184 (43%), Gaps = 33/184 (17%)
Query: 81 QEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFH 140
+E+E + + ++E + ++ Q+ E++ + R+ EQ E MG+ ++
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ-EGQMGEQEEQMG-E 210
Query: 141 MPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 200
E++ K+ + +EQ+ K+E+ + E V+ Q
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ------------------------ 246
Query: 201 AATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQST 260
+E+ +K EE + ++ ++ +++ ++Q+++ + KE+ E+ + Q
Sbjct: 247 -------EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR 299
Query: 261 QEEE 264
++EE
Sbjct: 300 EQEE 303
Score = 30.4 bits (67), Expect = 1.8
Identities = 25/126 (19%), Positives = 61/126 (48%), Gaps = 7/126 (5%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 61
+M ++ +++G E ++ ++ E ++ K + +GE E +QK+ + + ++
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE---EQMQKQEEQVRKQE-- 372
Query: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLA 121
E + K++E +R +++E + + + E KE++ Q+ E+K + R+
Sbjct: 373 --EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Query: 122 FEEQLE 127
EQ E
Sbjct: 431 MGEQKE 436
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/288 (19%), Positives = 124/288 (43%), Gaps = 38/288 (13%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
+E+ Q + SL+ + + + +++ E ++A K K + L + + L+ +
Sbjct: 91 VEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLY 150
Query: 61 HLKEIL---SKKQETLRILRLHCQEKESEAH-----------------------RKHTML 94
H+K L +K + L + H +++ E R L
Sbjct: 151 HMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKL 210
Query: 95 QECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDS 154
++ + L +Q+ + K +Q++L +E E L G+ + W M ++++EIC L
Sbjct: 211 EQSMREEALLKVQLTQFKESFQQVQLERDEYSEHLKGE-RARWQQRM-RKMSQEICTLKK 268
Query: 155 SKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKA 214
K+Q ++ + ++ +L +K+Q+ E P+ E +Q ++E +
Sbjct: 269 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSE----------VELQHLRKELERV 318
Query: 215 EELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQE 262
L A + +Q++ Q+Q+++ + +E L K ++ Q +S Q+
Sbjct: 319 AGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQ 366
Score = 28.5 bits (62), Expect = 6.9
Identities = 27/131 (20%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQAKKKA---NKDLGEARTICEALQKELDSLHGE 58
E Q +++V LE + L N++ E + A +L R E + EL +
Sbjct: 269 EKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKN 328
Query: 59 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 118
+ + +++E +R +++E +H LQ+ + S + +E N + +
Sbjct: 329 NQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLAKPQS-----VFKEPNNENKN 383
Query: 119 RLAFEEQLEDL 129
L E+Q+++L
Sbjct: 384 ALQLEQQVKEL 394
>gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 3 [Homo sapiens]
Length = 601
Score = 57.0 bits (136), Expect = 2e-08
Identities = 71/299 (23%), Positives = 127/299 (42%), Gaps = 45/299 (15%)
Query: 14 EPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETL 73
E +EV I R+N +Q K K N DL + ++E L V L+ L +K E
Sbjct: 132 ERELEVQIQRLN-IQ--KGKLNTDLYHTKRSLRYFEEESKDL---AVRLQHSLQRKGELE 185
Query: 74 RILRL--HCQEKESEAH------RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQ 125
R L Q+K++E R L++ + L Q+ + K ++++L +E
Sbjct: 186 RALSAVTATQKKKAERFSSRSKARTEWKLEQSMREQALLKAQLTQLKESLKEVQLERDEY 245
Query: 126 LEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEG 185
E L G+ + W M ++++E+C+L K+ + ++ +L +K+Q+ E
Sbjct: 246 AEHLKGE-RARWQQRM-RKMSQEVCSLKKEKKHDKYRVETLERSLSKLKNQMAEPLPPEP 303
Query: 186 PSTLDEG----LFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQR 241
P+ E L + A +Q E +++ L +R ++ Q++ +Q+++ Q+
Sbjct: 304 PAVPSEAELQHLRKELERVAGALQAQVEYNQRISLLNEGQKERLREQQERLPEQEERLQQ 363
Query: 242 L------------------------KEELEKHGMQVPAQAQSTQEE-EAGPGDVAPRPG 275
L KE EK G ++ S Q+E EA G AP PG
Sbjct: 364 LAEPQNSFKELNNENKSVLQLEQQVKELQEKLGKRLAHLVASAQKEPEAARGPGAPGPG 422
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 57.0 bits (136), Expect = 2e-08
Identities = 72/307 (23%), Positives = 132/307 (42%), Gaps = 51/307 (16%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
M++ QKV SLE ++ + ++ ++ + + K K L + + ++ELD G
Sbjct: 1507 MDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ 1566
Query: 61 HLKEI-LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE-KNKQRQL 118
L++ L + E R+ + H +E ES Q C++++ + +Q+EEE ++KQ+ L
Sbjct: 1567 MLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVL 1626
Query: 119 R--LAFEEQLEDLMGQHKDLWDFHMPERLAK---------------------------EI 149
R E +L L Q + DF +RL K EI
Sbjct: 1627 REKRELEGKLATLSDQ-VNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREI 1685
Query: 150 CALDSSKEQ-------LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAA 202
L + E+ +K K ++ +ED+ Q+ + A+ + L+E L +E
Sbjct: 1686 AQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI--AKAKTALEEQLSRLQREKNE 1743
Query: 203 TVQLFQEEHRKAEELL----AAAAQRHQ------QLQQKCQQQQQKRQRLKEELEKHGMQ 252
+E+ EL+ AA AQ + LQ + ++ +++Q L+E+L+ Q
Sbjct: 1744 IQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1803
Query: 253 VPAQAQS 259
V QS
Sbjct: 1804 VEFLEQS 1810
Score = 48.9 bits (115), Expect = 5e-06
Identities = 49/193 (25%), Positives = 91/193 (47%), Gaps = 28/193 (14%)
Query: 23 RINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQE 82
+IN++Q ++ANK+ E + +ALQ +++ L V K ++S+++ +R L +
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD-KSLVSRQEAKIRELETRLEF 1833
Query: 83 KESEAHRKHTMLQECKE-----------RISALNLQIEEEKNKQRQLRLAFEEQLEDLMG 131
+ ++ R ++ KE RI+A N + E+ K QRQLR EE MG
Sbjct: 1834 ERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEE-----MG 1888
Query: 132 Q--HKDLWDFHMPERLAKEICALDSSKEQLLKEEKL-------VKATLED--VKHQLCSL 180
+ K+ L ++ +L+++ + L + KL ++A +ED + L
Sbjct: 1889 ELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDL 1948
Query: 181 CGAEGPSTLDEGL 193
+EG S +D L
Sbjct: 1949 INSEGDSDVDSEL 1961
Score = 38.1 bits (87), Expect = 0.009
Identities = 42/212 (19%), Positives = 85/212 (40%), Gaps = 17/212 (8%)
Query: 63 KEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL---- 118
+E + K E ++ LR ++ E E + + RIS L ++ +E+N
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 119 ------RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLED 172
RL E+++++L Q+ L + E+ ++ + +L++ ++ +D
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDAL-------KKQMEVMEMEVMEARLIRAAEINGEVDDD 1365
Query: 173 VKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKC 232
L +D QE +++ Q+ R+ E L ++ Q+
Sbjct: 1366 DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRAL 1425
Query: 233 QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
QQ ++K QRL EL+ + + Q E E
Sbjct: 1426 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Score = 35.8 bits (81), Expect = 0.043
Identities = 54/289 (18%), Positives = 112/289 (38%), Gaps = 40/289 (13%)
Query: 18 EVLINRINEVQQAK---KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLR 74
E + N+ E+QQ + +KA K+ E R + L+ + L E + + L
Sbjct: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLD 1313
Query: 75 ILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEK--------------NKQRQLRL 120
E E T K+++ + +++ E + + + RL
Sbjct: 1314 AETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
Query: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
+E + ++ D + + ++ +K QL + ++A E+ + L L
Sbjct: 1374 KYERAVREV-----DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQL 1428
Query: 181 ---CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQ-QKCQQQQ 236
C D L L Q+ +L +++ R EL +Q H++ Q +K Q+++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVR-NHELEKKQRRFDSEL----SQAHEEAQREKLQREK 1483
Query: 237 QKRQR---------LKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGR 276
+R++ LK++LE+ M + Q EA D++ + +
Sbjct: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 57.0 bits (136), Expect = 2e-08
Identities = 72/307 (23%), Positives = 132/307 (42%), Gaps = 51/307 (16%)
Query: 1 MEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
M++ QKV SLE ++ + ++ ++ + + K K L + + ++ELD G
Sbjct: 1507 MDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ 1566
Query: 61 HLKEI-LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE-KNKQRQL 118
L++ L + E R+ + H +E ES Q C++++ + +Q+EEE ++KQ+ L
Sbjct: 1567 MLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVL 1626
Query: 119 R--LAFEEQLEDLMGQHKDLWDFHMPERLAK---------------------------EI 149
R E +L L Q + DF +RL K EI
Sbjct: 1627 REKRELEGKLATLSDQ-VNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREI 1685
Query: 150 CALDSSKEQ-------LLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAA 202
L + E+ +K K ++ +ED+ Q+ + A+ + L+E L +E
Sbjct: 1686 AQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI--AKAKTALEEQLSRLQREKNE 1743
Query: 203 TVQLFQEEHRKAEELL----AAAAQRHQ------QLQQKCQQQQQKRQRLKEELEKHGMQ 252
+E+ EL+ AA AQ + LQ + ++ +++Q L+E+L+ Q
Sbjct: 1744 IQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1803
Query: 253 VPAQAQS 259
V QS
Sbjct: 1804 VEFLEQS 1810
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/165 (24%), Positives = 80/165 (48%), Gaps = 19/165 (11%)
Query: 23 RINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQE 82
+IN++Q ++ANK+ E + +ALQ +++ L V K ++S+++ +R L +
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD-KSLVSRQEAKIRELETRLEF 1833
Query: 83 KESEAHRKHTMLQECKE-----------RISALNLQIEEEKNKQRQLRLAFEEQLEDLMG 131
+ ++ R ++ KE RI+A N + E+ K QRQLR EE MG
Sbjct: 1834 ERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEE-----MG 1888
Query: 132 Q--HKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVK 174
+ K+ L ++ +L+++ + L + KL + D++
Sbjct: 1889 ELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
Score = 38.1 bits (87), Expect = 0.009
Identities = 42/212 (19%), Positives = 85/212 (40%), Gaps = 17/212 (8%)
Query: 63 KEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL---- 118
+E + K E ++ LR ++ E E + + RIS L ++ +E+N
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 119 ------RLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLED 172
RL E+++++L Q+ L + E+ ++ + +L++ ++ +D
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDAL-------KKQMEVMEMEVMEARLIRAAEINGEVDDD 1365
Query: 173 VKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKC 232
L +D QE +++ Q+ R+ E L ++ Q+
Sbjct: 1366 DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRAL 1425
Query: 233 QQQQQKRQRLKEELEKHGMQVPAQAQSTQEEE 264
QQ ++K QRL EL+ + + Q E E
Sbjct: 1426 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Score = 35.8 bits (81), Expect = 0.043
Identities = 54/289 (18%), Positives = 112/289 (38%), Gaps = 40/289 (13%)
Query: 18 EVLINRINEVQQAK---KKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLR 74
E + N+ E+QQ + +KA K+ E R + L+ + L E + + L
Sbjct: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLD 1313
Query: 75 ILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEK--------------NKQRQLRL 120
E E T K+++ + +++ E + + + RL
Sbjct: 1314 AETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
Query: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSL 180
+E + ++ D + + ++ +K QL + ++A E+ + L L
Sbjct: 1374 KYERAVREV-----DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQL 1428
Query: 181 ---CGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQ-QKCQQQQ 236
C D L L Q+ +L +++ R EL +Q H++ Q +K Q+++
Sbjct: 1429 KKKCQRLTAELQDTKLHLEGQQVR-NHELEKKQRRFDSEL----SQAHEEAQREKLQREK 1483
Query: 237 QKRQR---------LKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGR 276
+R++ LK++LE+ M + Q EA D++ + +
Sbjct: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 55.8 bits (133), Expect = 4e-08
Identities = 59/265 (22%), Positives = 115/265 (43%), Gaps = 30/265 (11%)
Query: 9 KVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSK 68
+V LE + + + + ++++ + E + E LQ +L+ E H + L+
Sbjct: 1128 EVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALAS 1187
Query: 69 KQETLRILRLHCQEKES--------------EAHRKHTMLQECKERISALNLQIEEEKNK 114
Q L R Q+ EA RK++++ +E +S LN Q+ E++ +
Sbjct: 1188 AQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Query: 115 QRQLR---LAFEEQLEDLMGQHKDLW--DFHMPERLAKEICALDSSKEQLLKEEKLVKAT 169
++L+ +A E+ + L + + L R A+ AL + L +E + +
Sbjct: 1248 SKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVA 1307
Query: 170 LEDVKHQLCSLCGAEGPSTLDEGL------FLRSQEAAATVQLFQEEHRKAEELLAAAAQ 223
E+++ +L S AE L + L F + ++A +T+QL EH + L++
Sbjct: 1308 SENLRQELTSQ--AERAEELGQELKAWQEKFFQKEQALSTLQL---EHTSTQALVSELLP 1362
Query: 224 RHQQLQQKCQQQQQKRQRLKEELEK 248
QQ +Q +R +EELE+
Sbjct: 1363 AKHLCQQLQAEQAAAEKRHREELEQ 1387
Score = 52.0 bits (123), Expect = 6e-07
Identities = 59/273 (21%), Positives = 121/273 (44%), Gaps = 17/273 (6%)
Query: 5 QKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKE 64
+K K+ L+ +++V + Q + +A ++ E E LQ +++ E+ +
Sbjct: 612 EKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQA 671
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTM---LQECKERISALNLQIEEEKNKQRQLRLA 121
+++ + LR + EKE A K + LQ KE + +EEEK + A
Sbjct: 672 QVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAAD---A 728
Query: 122 FEEQ---LEDLMGQHKDLWDFHMPER--LAKEICALDSSKEQLLKEEKLVKATLEDVKHQ 176
EEQ + +L + + L + H ER L +E + +L + + +A E ++ +
Sbjct: 729 LEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRE 788
Query: 177 LCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQ 236
L A+ T + +E AA + +++ ++ + A ++ L+++C++ +
Sbjct: 789 LAEAMAAQ--HTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKAR 846
Query: 237 QKRQRLKEE---LEKHG-MQVPAQAQSTQEEEA 265
Q+ Q KE+ +E H +Q+ Q E A
Sbjct: 847 QELQEAKEKVAGIESHSELQISRQQNELAELHA 879
Score = 47.4 bits (111), Expect = 1e-05
Identities = 63/260 (24%), Positives = 108/260 (41%), Gaps = 19/260 (7%)
Query: 5 QKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKE 64
QK Q++ + + E R + QQ A + R AL K+L++L EK E
Sbjct: 562 QKEQQLKEVAEKQEA--TRQDHAQQLATAAEEREASLRERDAAL-KQLEALEKEKAAKLE 618
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEE 124
IL ++ + R Q ++A R+ E ++ L +E + +Q + + E
Sbjct: 619 ILQQQLQVANEARDSAQTSVTQAQREKA---ELSRKVEELQACVETARQEQHEAQAQVAE 675
Query: 125 QLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAE 184
L + + + ER+A+E L + L + K+ K +LE+ K +
Sbjct: 676 LELQLRSEQQKATE---KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR-------- 724
Query: 185 GPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKE 244
L+E S+ A T L ++ R+ +EL A R + L+ + QQ + Q E
Sbjct: 725 AADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGR-KGLEARLQQLGEAHQAETE 783
Query: 245 ELEKHGMQVPAQAQSTQEEE 264
L + + A AQ T E E
Sbjct: 784 VLRRELAEAMA-AQHTAESE 802
Score = 43.5 bits (101), Expect = 2e-04
Identities = 58/290 (20%), Positives = 133/290 (45%), Gaps = 26/290 (8%)
Query: 5 QKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKE 64
++ Q++ SL ++ I+ +++ ++ ++A++ G T ++ SL E L
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTA------QVASLTSELTTLNA 512
Query: 65 ILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEE----KNKQRQLRL 120
+ ++ + L L+ +EK+++ + LQ+ ++ L Q+E+ K K++QL+
Sbjct: 513 TIQQQDQELAGLKQQAKEKQAQLAQT---LQQQEQASQGLRHQVEQLSSSLKQKEQQLKE 569
Query: 121 AFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQL--LKEEKLVKATLEDVKHQLC 178
E+Q E H ER A + D++ +QL L++EK K + + Q+
Sbjct: 570 VAEKQ-EATRQDHAQQLATAAEEREAS-LRERDAALKQLEALEKEKAAKLEILQQQLQVA 627
Query: 179 SLCGAEGPSTLDEG------LFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKC 232
+ +++ + L + +E A V+ ++E +A+ +A + + QQK
Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKA 687
Query: 233 QQQQ---QKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVAPRPGRPVT 279
+++ Q++ +L+E+L+ + S +EE+ D R ++
Sbjct: 688 TEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCIS 737
Score = 42.7 bits (99), Expect = 4e-04
Identities = 72/283 (25%), Positives = 121/283 (42%), Gaps = 44/283 (15%)
Query: 9 KVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEI--- 65
K+ ++ L + +NE+ + KA ++ E + L+KEL + +K L+E
Sbjct: 326 KLREFASHLQQLQDALNELTEEHSKATQEWLEKQA---QLEKELSAALQDKKCLEEKNEI 382
Query: 66 ----LSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISAL---NLQI-------EEE 111
LS+ +E L L+ + +++ E L+ K+ + L N Q+ E E
Sbjct: 383 LQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETE 442
Query: 112 KNKQRQLRLA----FEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVK 167
+ +Q LA FEE+ + L DL I L +KE+L E+ +
Sbjct: 443 RGQQEAKLLAERGHFEEEKQQLSSLITDL---------QSSISNLSQAKEEL---EQASQ 490
Query: 168 ATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQ 227
A + Q+ SL +TL+ + + QE A Q +E+ + + L Q Q
Sbjct: 491 AHGARLTAQVASLTSEL--TTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQG 548
Query: 228 LQQKCQQQ----QQKRQRLKEELEKH--GMQVPAQAQSTQEEE 264
L+ + +Q +QK Q+LKE EK Q AQ +T EE
Sbjct: 549 LRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEE 591
Score = 42.4 bits (98), Expect = 5e-04
Identities = 67/287 (23%), Positives = 115/287 (40%), Gaps = 56/287 (19%)
Query: 6 KLQKVGSL-EPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKEL----DSLHGEKV 60
+LQ++G + EVL + E A+ A + CE L KE+ + +
Sbjct: 770 RLQQLGEAHQAETEVLRRELAEAMAAQHTAESE-------CEQLVKEVAAWRERYEDSQQ 822
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALN----LQIEEEKNKQR 116
+ + QE L L+ C++ E LQE KE+++ + LQI ++N+
Sbjct: 823 EEAQYGAMFQEQLMTLKEECEKARQE-------LQEAKEKVAGIESHSELQISRQQNELA 875
Query: 117 QLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKE----EKLVK----- 167
+L L+ + Q K++ ++LA ++ L KE E LV+
Sbjct: 876 ELHANLARALQQV--QEKEV----RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 929
Query: 168 ---ATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQR 224
A+ E VK + G P L+E + ++ +T Q R+AE++ +
Sbjct: 930 QETASRELVKEP--ARAGDRQPEWLEEQ---QGRQFCSTQAALQAMEREAEQMGNELERL 984
Query: 225 HQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVA 271
L + QQQ++R G Q A+ TQE D+A
Sbjct: 985 RAALMESQGQQQEER----------GQQEREVARLTQERGRAQADLA 1021
Score = 41.6 bits (96), Expect = 8e-04
Identities = 78/315 (24%), Positives = 125/315 (39%), Gaps = 59/315 (18%)
Query: 3 MVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQ-------KELDSL 55
+ +K ++ ++ R++ L +NE Q A K+L E R E+L K+ L
Sbjct: 244 LTEKDAQIAMMQQRIDRLA-LLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDL 302
Query: 56 HGEKVHLKEILSKKQET-------LRILRLHCQEKE------SEAHRKHTMLQECKERIS 102
EK + +++ E LR H Q+ + +E H K T QE E+ +
Sbjct: 303 KTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKAT--QEWLEKQA 360
Query: 103 ALNLQIE---------EEKNKQRQLRLAFEE----QLEDLMGQHKD--LWDFHMPERLAK 147
L ++ EEKN+ Q +L+ E QL+D Q K L D E L +
Sbjct: 361 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ 420
Query: 148 EICALDSSKEQLL------------KEEKLV--KATLEDVKHQLCSLCGAEGPSTLDEGL 193
E L ++ QL +E KL+ + E+ K QL SL + L +
Sbjct: 421 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLI-----TDLQSSI 475
Query: 194 FLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQV 253
SQ Q Q + +A+ L QQQ Q+ LK++ ++ Q+
Sbjct: 476 SNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQL 535
Query: 254 PAQAQSTQEEEAGPG 268
Q Q+E+A G
Sbjct: 536 AQTLQ--QQEQASQG 548
Score = 40.8 bits (94), Expect = 0.001
Identities = 50/247 (20%), Positives = 108/247 (43%), Gaps = 28/247 (11%)
Query: 2 EMVQKLQKVGSLEPRVEVLINRINEVQQ--AKKKANKDLGEARTICEALQKELDSLHGEK 59
E+ LQ LE + E+L +++++++ ++ + N + + + LQ L++L E
Sbjct: 365 ELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQ--LETLKQEA 422
Query: 60 VHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLR 119
L ++ Q + +L ++E++ + +E K+++S+L ++ + Q +
Sbjct: 423 ATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAK 482
Query: 120 LAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCS 179
E+LE H RL ++ +L S E + AT++ +L
Sbjct: 483 ----EELEQASQAHG--------ARLTAQVASLTS-------ELTTLNATIQQQDQELAG 523
Query: 180 LCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKR 239
L L+ QE A+ Q + E+L ++ Q+ QQL++ ++Q+ R
Sbjct: 524 LKQQAKEKQAQLAQTLQQQEQAS-----QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578
Query: 240 QRLKEEL 246
Q ++L
Sbjct: 579 QDHAQQL 585
Score = 40.4 bits (93), Expect = 0.002
Identities = 65/260 (25%), Positives = 119/260 (45%), Gaps = 46/260 (17%)
Query: 26 EVQQAKKKANKDLGEARTICEALQKELDSLH---GEKVHLKEILSKKQETLRILRLHCQE 82
E A+K+ ++L +++ L+ EL GE + L++ +++++ T + LR E
Sbjct: 1373 EQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRA---E 1429
Query: 83 KESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMP 142
K S A + +ML++ ++ N + E N RQ LE + Q +
Sbjct: 1430 KASYAEQL-SMLKKAHGLLAEENRGLGERANLGRQF-------LEVELDQAR-------- 1473
Query: 143 ERLAKEICALDSSKEQLLKE-EKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAA 201
E+ +E+ A+ + E L E ++ ++T +++ GA+ L+E + +
Sbjct: 1474 EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAK-VKVLEERQRFQEERQK 1532
Query: 202 ATVQL-----FQEEHRK-AEEL---LAAAAQRHQQLQQKCQ-------QQQQKRQRLKEE 245
T Q+ FQ E K EEL LA + Q + QQK + + QQ+ QRL+ +
Sbjct: 1533 LTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQ 1592
Query: 246 LEKHGMQVPAQAQSTQEEEA 265
L + QAQ +Q+E+A
Sbjct: 1593 LNE------LQAQLSQKEQA 1606
Score = 40.0 bits (92), Expect = 0.002
Identities = 70/321 (21%), Positives = 127/321 (39%), Gaps = 60/321 (18%)
Query: 3 MVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQK---ELDSLHGEK 59
+ Q ++ L +VE L + +Q + +A + E + Q+ E + + EK
Sbjct: 638 VTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEK 697
Query: 60 VHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQ----IEEEKNKQ 115
L+E L +E+L++ + +E E R L+E + IS L + +E+ K ++
Sbjct: 698 DQLQEQLQALKESLKVTKGSLEE---EKRRAADALEEQQRCISELKAETRSLVEQHKRER 754
Query: 116 RQL------RLAFEEQLEDLMGQHK---DLWDFHMPERLAKEICALDSSKEQLLKEEKLV 166
++L R E +L+ L H+ ++ + E +A + A +S EQL+KE
Sbjct: 755 KELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTA-ESECEQLVKEVAAW 813
Query: 167 KATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAA----- 221
+ ED + + A+ + E L +E Q QE K + + +
Sbjct: 814 RERYEDSQQE-----EAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQIS 868
Query: 222 ------AQRHQQLQQKCQQQQQKR---QRLKEELE---------------------KHGM 251
A+ H L + QQ Q+K Q+L ++L K G
Sbjct: 869 RQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGE 928
Query: 252 QVPAQAQSTQEEEAGPGDVAP 272
Q ++ +E A GD P
Sbjct: 929 QQETASRELVKEPARAGDRQP 949
Score = 37.4 bits (85), Expect = 0.015
Identities = 48/225 (21%), Positives = 92/225 (40%), Gaps = 42/225 (18%)
Query: 59 KVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQL 118
+V L + K + L +R + + +E R+ Q + + + E K K +
Sbjct: 1466 EVELDQAREKYVQELAAVRADAETRLAEVQRE---AQSTARELEVMTAKYEGAKVKVLEE 1522
Query: 119 RLAFEEQLEDLMGQHKDLWDFHMP-----ERLAKEICALDSSKEQLLKEEKLVKATLEDV 173
R F+E+ + L Q + L F E L+K++ DS + ++++KL
Sbjct: 1523 RQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLA--DSDQASKVQQQKLKAVQ---- 1576
Query: 174 KHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEH---------RKAEELLAAAAQR 224
A+G + E L++Q QL Q+E KA+ A Q+
Sbjct: 1577 ---------AQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ 1627
Query: 225 HQQLQQKCQQQQQ----------KRQRLKEELEKHGMQVPAQAQS 259
+Q+LQ++ + +Q + +RL EL++ G++ Q+
Sbjct: 1628 NQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQT 1672
Score = 35.8 bits (81), Expect = 0.043
Identities = 57/266 (21%), Positives = 110/266 (41%), Gaps = 44/266 (16%)
Query: 5 QKLQKVGSLEPRVEVLINRINEVQQ-AKKKANKDLGEA-------------RTIC----- 45
+K+ R+E L+ + E Q+ A ++ K+ A R C
Sbjct: 907 EKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAA 966
Query: 46 -EALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISAL 104
+A+++E + + E L+ L + Q QE+ + R+ L + + R A
Sbjct: 967 LQAMEREAEQMGNELERLRAALMESQGQQ-------QEERGQQEREVARLTQERGRAQA- 1018
Query: 105 NLQIEEEKNKQRQLRLAF---EEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLK 161
+L +E+ + ++RL E+++E Q E +E+ L + +K
Sbjct: 1019 DLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIK 1078
Query: 162 EEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAA 221
E + ++ T++ +K QL A+ G +S+ A T + K E L A
Sbjct: 1079 ELEELRQTVKQLKEQL-----AKKEKEHASGSGAQSEAAGRT----EPTGPKLEALRAEV 1129
Query: 222 AQRHQQLQQKCQQQQQKRQRLKEELE 247
++ L+Q+CQ+QQ++ L+ LE
Sbjct: 1130 SK----LEQQCQKQQEQADSLERSLE 1151
Score = 35.4 bits (80), Expect = 0.057
Identities = 44/213 (20%), Positives = 89/213 (41%), Gaps = 31/213 (14%)
Query: 16 RVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRI 75
+V+VL R Q+ ++K + + K+++ L + + +Q+ L+
Sbjct: 1516 KVKVLEER-QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKA 1574
Query: 76 LRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKD 135
++ E + EA R L E + ++S E K + + + ++ + + Q+++
Sbjct: 1575 VQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQ----QNQE 1630
Query: 136 LWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFL 195
L E+L S EQL KE K ++A E + H+L + L
Sbjct: 1631 L-----QEQLR--------SLEQLQKENKELRAEAERLGHEL-------------QQAGL 1664
Query: 196 RSQEAAATVQLFQEEHRKAEELLAAAAQRHQQL 228
+++EA T + + R E +A A Q+ + L
Sbjct: 1665 KTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1697
>gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 4 [Homo sapiens]
Length = 590
Score = 55.5 bits (132), Expect = 5e-08
Identities = 71/300 (23%), Positives = 128/300 (42%), Gaps = 46/300 (15%)
Query: 14 EPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETL 73
E +EV I R+N +Q K K N DL + ++E L V L+ L +K E
Sbjct: 120 ERELEVQIQRLN-IQ--KGKLNTDLYHTKRSLRYFEEESKDL---AVRLQHSLQRKGELE 173
Query: 74 RILRL--HCQEKESEAH------RKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQ 125
R L Q+K++E R L++ + L Q+ + K ++++L +E
Sbjct: 174 RALSAVTATQKKKAERFSSRSKARTEWKLEQSMREQALLKAQLTQLKESLKEVQLERDEY 233
Query: 126 LEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEG 185
E L G+ + W M ++++E+C+L K+ + ++ +L +K+Q+ E
Sbjct: 234 AEHLKGE-RARWQQRM-RKMSQEVCSLKKEKKHDKYRVETLERSLSKLKNQMAEPLPPEP 291
Query: 186 PSTLDEG----LFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQR 241
P+ E L + A +Q E +++ L +R ++ Q++ +Q+++ Q+
Sbjct: 292 PAVPSEAELQHLRKELERVAGALQAQVEYNQRISLLNEGQKERLREQQERLPEQEERLQQ 351
Query: 242 LKE------EL---EKHGMQVPAQAQSTQEE-----------------EAGPGDVAPRPG 275
L E EL K +Q+ Q + QE+ EA G AP PG
Sbjct: 352 LAEPQNSFKELNNENKSVLQLEQQVKELQEKLGKVKETVTSTPSKKEPEAARGPGAPGPG 411
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 55.5 bits (132), Expect = 5e-08
Identities = 61/257 (23%), Positives = 118/257 (45%), Gaps = 17/257 (6%)
Query: 2 EMVQKLQ-KVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKV 60
E+++K ++ ++ R+ L +R+ EV+Q + A KDL + + Q+++ E +
Sbjct: 275 ELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDI----REAM 330
Query: 61 HLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRL 120
KE + ++ TL L Q + + H + L+ A+ Q+ EEKN+Q Q RL
Sbjct: 331 AQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQM-EEKNRQLQERL 389
Query: 121 AFEEQ-LEDLMGQHKDLWDFHMPERLAKEICALDSSKEQ---LLKEEKLVKATLEDVKHQ 176
EQ L+ M + + L + + LA+ I AL ++E+ + + + ++ LE+ +
Sbjct: 390 ELAEQKLQQTMRKAETLPE--VEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQE 447
Query: 177 L-----CSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQK 231
L E L + + E+ +QL +E A E Q + ++
Sbjct: 448 LQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKN 507
Query: 232 CQQQQQKRQRLKEELEK 248
++ ++RL EE+EK
Sbjct: 508 LEESLHDKERLAEEIEK 524
Score = 36.2 bits (82), Expect = 0.033
Identities = 42/157 (26%), Positives = 78/157 (49%), Gaps = 14/157 (8%)
Query: 27 VQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESE 86
++ A++K + + +A T+ E ++ EL +E +E +R L +EK E
Sbjct: 389 LELAEQKLQQTMRKAETLPE-VEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQE 447
Query: 87 ---AHRKHTMLQECKERISALNLQIEEEKNKQRQLRL-----AFEEQ---LEDLMGQHKD 135
A ++ M +E +R+S ++ E N++ QL L A EE+ +++ K+
Sbjct: 448 LQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKN 507
Query: 136 LWD-FHMPERLAKEICALDSSKEQL-LKEEKLVKATL 170
L + H ERLA+EI L S +QL ++ L++ T+
Sbjct: 508 LEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTI 544
>gi|239745087 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 547
Score = 55.1 bits (131), Expect = 7e-08
Identities = 62/272 (22%), Positives = 121/272 (44%), Gaps = 30/272 (11%)
Query: 14 EPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETL 73
E +EV I R+N +Q K K N DL + ++E L V L+ L +K E
Sbjct: 140 ERELEVQIQRLN-IQ--KGKLNTDLYHTKRSLRYFEEESKDL---AVRLQHSLQRKGELE 193
Query: 74 RILRLHCQEKESEAHRKHTM---------LQECKERISALNLQIEEEKNKQRQLRLAFEE 124
R L ++ +A R+ + L++ + L Q+ + K ++++L +E
Sbjct: 194 RALSAVTATQKKKAERQFSSRSKARTEWKLEQSMREQALLKAQLTQLKESLKEVQLERDE 253
Query: 125 QLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAE 184
E L G+ + W M ++++E+C+L K+ + ++ +L +K+Q+ E
Sbjct: 254 YAEHLKGE-RARWQQRM-RKMSQEVCSLKKEKKHDKYRVETLERSLSKLKNQMAEPLPPE 311
Query: 185 GPSTLDEG----LFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQ 240
P+ E L + A +Q E +++ L +R ++ Q++ +Q+++ Q
Sbjct: 312 PPAVPSEAELQHLRKELERVAGALQAQVEYNQRISLLNEGQKERLREQQERLPEQEERLQ 371
Query: 241 RLKE------EL---EKHGMQVPAQAQSTQEE 263
+L E EL K +Q+ Q + QE+
Sbjct: 372 QLAEPQNSFKELNNENKSVLQLEQQVKELQEK 403
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,287,798
Number of Sequences: 37866
Number of extensions: 551537
Number of successful extensions: 10564
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 380
Number of HSP's successfully gapped in prelim test: 759
Number of HSP's that attempted gapping in prelim test: 4259
Number of HSP's gapped (non-prelim): 3948
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.