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Search of human proteins with 185135971
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
(614 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 1241 0.0
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 847 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 802 0.0
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 792 0.0
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 792 0.0
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 790 0.0
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 489 e-138
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 439 e-123
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 298 1e-80
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 298 1e-80
gi|38201714 ELAV-like 1 [Homo sapiens] 124 2e-28
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 121 2e-27
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 117 4e-26
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 115 1e-25
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 115 1e-25
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 115 1e-25
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 115 1e-25
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 114 3e-25
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 110 3e-24
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 107 3e-23
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 105 9e-23
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 104 2e-22
gi|239753150 PREDICTED: similar to poly(A) binding protein, cyto... 103 4e-22
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 102 1e-21
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 99 9e-21
gi|55956788 nucleolin [Homo sapiens] 92 1e-18
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 91 4e-18
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 91 4e-18
gi|4506449 RNA binding motif, single stranded interacting protei... 88 3e-17
gi|4506447 RNA binding motif, single stranded interacting protei... 86 8e-17
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 1241 bits (3211), Expect = 0.0
Identities = 614/614 (100%), Positives = 614/614 (100%)
Query: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ
Sbjct: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
Query: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
Query: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE
Sbjct: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
Query: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK
Sbjct: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
Query: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN
Sbjct: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
Query: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT
Sbjct: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
Query: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAY 420
KPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAY
Sbjct: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAY 420
Query: 421 YGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQR 480
YGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQR
Sbjct: 421 YGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQR 480
Query: 481 VANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQEPLTASMLAAAP 540
VANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQEPLTASMLAAAP
Sbjct: 481 VANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQEPLTASMLAAAP 540
Query: 541 LHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVL 600
LHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVL
Sbjct: 541 LHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVL 600
Query: 601 QAHQAMEQPKAYMH 614
QAHQAMEQPKAYMH
Sbjct: 601 QAHQAMEQPKAYMH 614
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 847 bits (2189), Expect = 0.0
Identities = 432/622 (69%), Positives = 501/622 (80%), Gaps = 16/622 (2%)
Query: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
MN S YP+ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
QPADAERALDTMNF+++KG+P+RIMWSQRDP LRKSGVGNIFIKNL+ SIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
Query: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
FGNILSCKV CDE+GS+G+GFVHFET EAA++AI MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
AELGARA EFTN+Y+KN D+D++ L+DLF +FG LSVKVM D SG S+ FGFV+FE+
Sbjct: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
Query: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
HE+AQKAV MNGKE++G+ +Y GRAQK+VERQ ELKR+FEQMKQDR+ RYQGVNLYVKN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
Query: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
LDD IDD++LRKEFSP+G ITSAKVM EGG SKGFGFVCFSSPEEATKAVTEMNGRIV T
Sbjct: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
Query: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQ--QPSSYFLPAMPQPPAQA 418
KPLYVALAQRKEER+A LTNQYMQR++++R + NP++ +Q PS YF+ A+PQ +A
Sbjct: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA 420
Query: 419 AYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHT 478
AYY + +P+PRWT+Q RP + + P P S++R AS+QVPR V T
Sbjct: 421 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPR-VMST 479
Query: 479 QRVANIGTQTTGP---SGVGCCTPGRPLLPCKCSSA----------AHSTYRVQEPAVHI 525
QRVAN TQT GP + TP +P +A A +Q+PAVH+
Sbjct: 480 QRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV 539
Query: 526 PGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLES 585
GQEPLTASMLA+AP EQKQM+GERL+PLI +H LAGKITGMLLEIDNSELL MLES
Sbjct: 540 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES 599
Query: 586 PESLHAKIDEAVAVLQAHQAME 607
PESL +K+DEAVAVLQAHQA E
Sbjct: 600 PESLRSKVDEAVAVLQAHQAKE 621
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 802 bits (2071), Expect = 0.0
Identities = 418/623 (67%), Positives = 491/623 (78%), Gaps = 20/623 (3%)
Query: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
MNA+ S YP+ASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
QPADAERALDTMNF+++KG+PIRIMWSQRDP LRKSGVGN+FIKNL+ SIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
FGNILSCKV CDE+GS+G+ FVHFET EAA +AI MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
AELGA+A EFTN+Y+KN +VD++ L++LFSQFGK LSVKVMRD +G S+ FGFV++EK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
HE+A KAV MNGKE+SG++++ GRAQK+VERQ ELKR+FEQ+KQ+R+ RYQGVNLY+KN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
LDD+IDD+KLRKEFSP+G ITSAKVM E G SKGFGFVCFSSPEEATKAVTEMNGRIVG+
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTL-SNPLLGSFQQPS-SYFLPAMPQPPAQA 418
KPLYVALAQRKEERKA LTNQYMQR++ MR L +N +L FQ + YF+PA+PQ +
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
Query: 419 AYYGCGPVTPTQPAPRWTSQPPRP----SCASMVRPPVVPRRPPAHISSV--RQASTQVP 472
YY + +P PRW Q RP S +R PR H++ AS +P
Sbjct: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQS-GPRPTLRHLAPTGNAPASRGLP 478
Query: 473 RTVPHTQRV-ANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTY------RVQEPAVHI 525
T TQRV Q P R + P K +S+ S + + +PAVH+
Sbjct: 479 TT---TQRVGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHV 535
Query: 526 PGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLES 585
GQEPLTASMLAAAP EQKQM+GERL+PLI +H+ LAGKITGMLLEIDNSELL MLES
Sbjct: 536 QGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLES 595
Query: 586 PESLHAKIDEAVAVLQAHQAMEQ 608
PESL +K+DEAVAVLQAH A ++
Sbjct: 596 PESLRSKVDEAVAVLQAHHAKKE 618
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 792 bits (2045), Expect = 0.0
Identities = 408/632 (64%), Positives = 488/632 (77%), Gaps = 25/632 (3%)
Query: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
MNA+ S YP+ASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
QPADAERALDTMNF+++KG+PIRIMWSQRDP LRKSGVGN+FIKNL+ SIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
FGNILSCKV CDE+GS+G+ FVHFET EAA +AI MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
AELGA+A EFTN+Y+KN +VD++ L++LFSQFGK LSVKVMRD +G S+ FGFV++EK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
HE+A KAV MNGKE+SG++++ GRAQK+VERQ ELKR+FEQ+KQ+R+ RYQGVNLY+KN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
LDD+IDD+KLRKEFSP+G ITSAKVM E G SKGFGFVCFSSPEEATKAVTEMNGRIVG+
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTL-SNPLLGSFQQPS-SYFLPAMPQPPAQA 418
KPLYVALAQRKEERKA LTNQYMQR++ MR L +N +L FQ + YF+PA+PQ +
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
Query: 419 AYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVP------ 472
YY + +P PRW Q RP + + P + + ++ P
Sbjct: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMD 479
Query: 473 --------RTVPHTQRVANIGT--QTTGPSGVGCCTPGRPLLPCKCSSAAHSTY------ 516
+ + + + + T Q P R + P K +S+ S +
Sbjct: 480 FGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPL 539
Query: 517 RVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDN 576
+ +PAVH+ GQEPLTASMLAAAP EQKQM+GERL+PLI +H+ LAGKITGMLLEIDN
Sbjct: 540 QAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDN 599
Query: 577 SELLLMLESPESLHAKIDEAVAVLQAHQAMEQ 608
SELL MLESPESL +K+DEAVAVLQAH A ++
Sbjct: 600 SELLHMLESPESLRSKVDEAVAVLQAHHAKKE 631
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 792 bits (2045), Expect = 0.0
Identities = 418/652 (64%), Positives = 492/652 (75%), Gaps = 49/652 (7%)
Query: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
MNA+ S YP+ASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
QPADAERALDTMNF+++KG+PIRIMWSQRDP LRKSGVGN+FIKNL+ SIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
FGNILSCKV CDE+GS+G+ FVHFET EAA +AI MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
AELGA+A EFTN+Y+KN +VD++ L++LFSQFGK LSVKVMRD +G S+ FGFV++EK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
HE+A KAV MNGKE+SG++++ GRAQK+VERQ ELKR+FEQ+KQ+R+ RYQGVNLY+KN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
LDD+IDD+KLRKEFSP+G ITSAKVM E G SKGFGFVCFSSPEEATKAVTEMNGRIVG+
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTL-SNPLLGSFQQPS-SYFLPAMPQPPAQA 418
KPLYVALAQRKEERKA LTNQYMQR++ MR L +N +L FQ + YF+PA+PQ +
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
Query: 419 AYYGCGPVTPTQPAPRWTSQPPRP----SCASMVRPPVVPRRPPAHISSV--RQASTQVP 472
YY + +P PRW Q RP S +R PR H++ AS +P
Sbjct: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQS-GPRPTLRHLAPTGNAPASRGLP 478
Query: 473 RTVPHTQRVAN------------------------------IGTQTTGPSGVGCCTPGRP 502
T TQRV + Q P R
Sbjct: 479 TT---TQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRA 535
Query: 503 LLPCKCSSAAHSTY------RVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLI 556
+ P K +S+ S + + +PAVH+ GQEPLTASMLAAAP EQKQM+GERL+PLI
Sbjct: 536 VAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLI 595
Query: 557 HDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVLQAHQAMEQ 608
+H+ LAGKITGMLLEIDNSELL MLESPESL +K+DEAVAVLQAH A ++
Sbjct: 596 QTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKE 647
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 790 bits (2040), Expect = 0.0
Identities = 409/621 (65%), Positives = 476/621 (76%), Gaps = 19/621 (3%)
Query: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
MN S YP ASLYVGDLHPDVTEAMLYEKFSPAGPILSIR+CRD+ T S YAY+NFQ
Sbjct: 1 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60
Query: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
DAE ALDTMNF+++KG+P+RIMWSQRDP LRKSGVGNIF+KNL+ SI+NKALYDT S
Sbjct: 61 HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 120
Query: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
FGNILSC V CDE+GS+G+GFVHFETHEAA++AI MNGMLLN RKVFVG FKSR+ERE
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180
Query: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
AELGARA EF N+Y+KN D+D++ L+DLF +FG LSVKVM D SG S+ FGFV+FE+
Sbjct: 181 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
Query: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
HE+AQKAV MNGKE++G+ +Y GRAQK+VERQ ELKR FEQMKQDR+ RYQ VNLYVKN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKN 300
Query: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
LDD IDD++LRK FSP+G ITSAKVM EGG SKGFGFVCFSSPEEATKAVTEMNGRIV T
Sbjct: 301 LDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
Query: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAY 420
KPLYVALAQRKEER+A LTN+YMQR++++R + N PS YF+ A+PQ AAY
Sbjct: 361 KPLYVALAQRKEERQAYLTNEYMQRMASVRAVPN----QRAPPSGYFMTAVPQTQNHAAY 416
Query: 421 YGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQR 480
Y + +P+PRWT+Q RP + P P S++R AS+QVPR V TQR
Sbjct: 417 YPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPR-VMSTQR 475
Query: 481 VANIGTQTTGP----SGVGCCTPGRPLLPCKCSSA----------AHSTYRVQEPAVHIP 526
VAN TQT GP + TP +P +A A +Q+ AVH+
Sbjct: 476 VANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHVQ 535
Query: 527 GQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESP 586
GQE LTAS LA+AP +QKQM+GERL+PLI +H LAGKITGMLLEIDNSELL MLESP
Sbjct: 536 GQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLESP 595
Query: 587 ESLHAKIDEAVAVLQAHQAME 607
ESL +K+DEAVAVLQAHQA E
Sbjct: 596 ESLRSKVDEAVAVLQAHQAKE 616
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 489 bits (1260), Expect = e-138
Identities = 233/363 (64%), Positives = 299/363 (82%)
Query: 8 YPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAER 67
Y +ASLYVGDLH DVTE +L+ KFS GP+LSIR+CRD TRRSLGYAY+NF Q ADA++
Sbjct: 7 YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQK 66
Query: 68 ALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILS 127
ALDTMNF+++KG+ IR+MWSQRD LR+SG+GN+FIKNL+ SIDNK LY+ FS FG ILS
Sbjct: 67 ALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILS 126
Query: 128 CKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARA 187
KV D+ GS+G+ FVHF+ AA +AI MNG LL KVFVG FK+R++REAEL ++A
Sbjct: 127 SKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKA 186
Query: 188 LEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKA 247
EFTN+Y+KN D+D++ L+D+FS++GK LSVKVM D+SG S+ FGFV+F+ HE A+KA
Sbjct: 187 SEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKA 246
Query: 248 VVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDD 307
V MNG++++G+L++ GRAQK+VERQ ELK+ FEQ+K++R+R QGV LY+KNLDD+IDD
Sbjct: 247 VEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDD 306
Query: 308 DKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVAL 367
+KLR EFS +G I+ KVM E G SKGFG +CFSSPE+ATKA+TEMNGRI+G+KPL +AL
Sbjct: 307 EKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
Query: 368 AQR 370
AQR
Sbjct: 367 AQR 369
Score = 171 bits (432), Expect = 2e-42
Identities = 104/293 (35%), Positives = 166/293 (56%), Gaps = 20/293 (6%)
Query: 95 KSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQ 152
K + ++++ +L + L+ FST G +LS ++ D+ S G+ +V+F AQ
Sbjct: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
Query: 153 QAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFS 212
+A++TMN ++ + + + +R+A L R N+++KNL +D + L + FS
Sbjct: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Query: 213 QFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVER 272
FGK+LS KVM D+ G S+ + FV+F+ A +A+ MNGK + G ++ GR + R +R
Sbjct: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
Query: 273 QNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEG-GH 331
+ EL+ + + N+Y+KN +DD++L+ FS YG S KVMT+ G
Sbjct: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
Query: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQ 384
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ER+A L + Q
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
Score = 96.7 bits (239), Expect = 6e-20
Identities = 63/199 (31%), Positives = 107/199 (53%), Gaps = 19/199 (9%)
Query: 185 ARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEE 243
A ++YV +L DV E L FS G +LS+++ RD + S + +VNF + +
Sbjct: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
Query: 244 AQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGV-NLYVKNLD 302
AQKA+ MN + G+ + R ++D R G+ N+++KNLD
Sbjct: 64 AQKALDTMNFDIIKGKSI-----------------RLMWSQRDAYLRRSGIGNVFIKNLD 106
Query: 303 DSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKP 362
SID+ L + FS +G I S+KVM++ SKG+ FV F + A +A+ EMNG+++
Sbjct: 107 KSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCK 166
Query: 363 LYVALAQRKEERKAILTNQ 381
++V + +++R+A L ++
Sbjct: 167 VFVGRFKNRKDREAELRSK 185
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 439 bits (1129), Expect = e-123
Identities = 216/365 (59%), Positives = 282/365 (77%), Gaps = 1/365 (0%)
Query: 8 YPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAER 67
Y A+LYVGDL PDVTE MLY+KF PAGP+ R+CRD TR LGY Y+NF+ PADAE
Sbjct: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Query: 68 ALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILS 127
AL+TMNF+++ G+P R+MWSQ D LRKSGVGNIFIKNL+ SIDN+AL+ FS FGNILS
Sbjct: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
Query: 128 CKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGAR- 186
CKV CD++GS+G+ +VHF++ AA +AI MNG+ LN+R+V+VG FK ER AE+ R
Sbjct: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
Query: 187 ALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQK 246
FTN++VKN+ D+D++ L++LF ++G SVKV+RD SG S+ FGFV +E HE AQK
Sbjct: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
Query: 247 AVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSID 306
AV+ ++GK + G++LY GRAQK++ER EL+RRFE+++ R GV +Y+KNLD++I+
Sbjct: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
Query: 307 DDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVA 366
D+KL++EFS +G I+ AKVM E G KGFG VCFSS EEATKAV EMNGRIVG+KPL+V
Sbjct: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
Query: 367 LAQRK 371
L Q +
Sbjct: 375 LGQAR 379
Score = 151 bits (381), Expect = 2e-36
Identities = 98/286 (34%), Positives = 157/286 (54%), Gaps = 21/286 (7%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINTM 158
+++ +L+ + LY F G + ++ D G+G+V+F A+ A+NTM
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 159 NGMLLNDRKV-FVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
N L+N + + R R++ +G NI++KNL +D + L LFS FG +
Sbjct: 80 NFDLINGKPFRLMWSQPDDRLRKSGVG-------NIFIKNLDKSIDNRALFYLFSAFGNI 132
Query: 218 LSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELK 277
LS KV+ D++G S+ + +V+F+ A +A+ HMNG ++ R +Y GR + ER E++
Sbjct: 133 LSCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVR 191
Query: 278 RRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEG-GHSKGFG 336
R R N++VKN+ D IDD+KL++ F YG S KV+ + G SKGFG
Sbjct: 192 TR---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
Query: 337 FVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQY 382
FV + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 243 FVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
Score = 76.3 bits (186), Expect = 8e-14
Identities = 49/188 (26%), Positives = 98/188 (52%), Gaps = 29/188 (15%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+++V ++ D+ + L E F GP S++V RD A+ +S G+ ++ ++ A++A+
Sbjct: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLD 258
Query: 72 MNFEMLKG----------------------QPIRIMWSQRDPGLRKSGVGNIFIKNLEDS 109
++ + + G + +R+ R PG+ I+IKNL+++
Sbjct: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP------IYIKNLDET 312
Query: 110 IDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVF 169
I+++ L + FS+FG+I KV + +GFG V F + E A +A++ MNG ++ + +
Sbjct: 313 INDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLH 372
Query: 170 VGHFKSRR 177
V ++RR
Sbjct: 373 VTLGQARR 380
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
Query: 289 RRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEA 346
++Y LYV +LD + +D L K+F P G + ++ + G+G+V F P +A
Sbjct: 13 KKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADA 72
Query: 347 TKAVTEMNGRIVGTKPLYVALAQRKEE-RKAILTNQYMQRL 386
A+ MN ++ KP + +Q + RK+ + N +++ L
Sbjct: 73 EWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 298 bits (763), Expect = 1e-80
Identities = 140/196 (71%), Positives = 169/196 (86%)
Query: 10 LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
+ASLYVGDLHP+VTEAMLYEKFSPAGPILSIR+CRD TRRSLGYAY+N+QQP DA+RAL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 70 DTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
+T+NF+++KG+P+RIMWSQRDP LRKSGVGN+FIKNL +IDNKALY+ FS FGNILSCK
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 130 VACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALE 189
VACDE G +G+GFVHF+ E+A++AI+ MNGM LN RK+FVG FKS +EREAE GA A +
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 190 FTNIYVKNLPVDVDEQ 205
T+ VK+ D DE+
Sbjct: 181 STSADVKDFEEDTDEE 196
Score = 91.3 bits (225), Expect = 2e-18
Identities = 55/180 (30%), Positives = 101/180 (56%), Gaps = 9/180 (5%)
Query: 98 VGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAI 155
+ ++++ +L + LY+ FS G ILS ++ D+ S G+ +V+++ A++A+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 156 NTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFG 215
T+N ++ R V + +R+ L R N+++KNL +D + L ++FS FG
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 216 KMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNE 275
+LS KV D G + +GFV+F+K E A++A+ MNG ++ R ++ GR + ER+ E
Sbjct: 115 NILSCKVACDEKG-PKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 83.6 bits (205), Expect = 5e-16
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 19/187 (10%)
Query: 192 NIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVH 250
++YV +L +V E L + FS G +LS+++ RD + S + +VN+++ +A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 251 MNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGV-NLYVKNLDDSIDDDK 309
+N + GR + R ++D R GV N+++KNL +ID+
Sbjct: 63 LNFDVIKGRPV-----------------RIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 310 LRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQ 369
L FS +G I S KV + KG+GFV F E A +A+ MNG + + ++V +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 370 RKEERKA 376
+ER+A
Sbjct: 166 SHKEREA 172
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 298 bits (763), Expect = 1e-80
Identities = 140/196 (71%), Positives = 169/196 (86%)
Query: 10 LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
+ASLYVGDLHP+VTEAMLYEKFSPAGPILSIR+CRD TRRSLGYAY+N+QQP DA+RAL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 70 DTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
+T+NF+++KG+P+RIMWSQRDP LRKSGVGN+FIKNL +IDNKALY+ FS FGNILSCK
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 130 VACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALE 189
VACDE G +G+GFVHF+ E+A++AI+ MNGM LN RK+FVG FKS +EREAE GA A +
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 190 FTNIYVKNLPVDVDEQ 205
T+ VK+ D DE+
Sbjct: 181 STSADVKDFEEDTDEE 196
Score = 91.3 bits (225), Expect = 2e-18
Identities = 55/180 (30%), Positives = 101/180 (56%), Gaps = 9/180 (5%)
Query: 98 VGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAI 155
+ ++++ +L + LY+ FS G ILS ++ D+ S G+ +V+++ A++A+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 156 NTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFG 215
T+N ++ R V + +R+ L R N+++KNL +D + L ++FS FG
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 216 KMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNE 275
+LS KV D G + +GFV+F+K E A++A+ MNG ++ R ++ GR + ER+ E
Sbjct: 115 NILSCKVACDEKG-PKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 83.6 bits (205), Expect = 5e-16
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 19/187 (10%)
Query: 192 NIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVH 250
++YV +L +V E L + FS G +LS+++ RD + S + +VN+++ +A++A+
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 251 MNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGV-NLYVKNLDDSIDDDK 309
+N + GR + R ++D R GV N+++KNL +ID+
Sbjct: 63 LNFDVIKGRPV-----------------RIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 310 LRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQ 369
L FS +G I S KV + KG+GFV F E A +A+ MNG + + ++V +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 370 RKEERKA 376
+ER+A
Sbjct: 166 SHKEREA 172
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 124 bits (312), Expect = 2e-28
Identities = 88/318 (27%), Positives = 154/318 (48%), Gaps = 49/318 (15%)
Query: 97 GVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG--SRGFGFVHFETHEAAQQA 154
G N+ + L ++ L FS+ G + S K+ D+ S G+GFV++ T + A++A
Sbjct: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
Query: 155 INTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQF 214
INT+NG+ L + + V + A + ++ N+Y+ LP + ++ ++D+FS+F
Sbjct: 78 INTLNGLRLQSKTIKVSY--------ARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
Query: 215 GKMLSVKVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG--------------- 258
G++++ +V+ D +G SR F+ F+K EA++A+ NG + G
Sbjct: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
Query: 259 -------RLLYAGRAQK---RVERQNELKRRFEQMKQDRLRRYQGVN----------LYV 298
LY A++ V Q + + RF M D + GVN +++
Sbjct: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
Query: 299 KNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR 356
NL D+ L + F P+G +T+ KV+ + KGFGFV ++ EEA A+ +NG
Sbjct: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
Query: 357 IVGTKPLYVALAQRKEER 374
+G K L V+ K +
Sbjct: 309 RLGDKILQVSFKTNKSHK 326
Score = 110 bits (275), Expect = 4e-24
Identities = 81/297 (27%), Positives = 140/297 (47%), Gaps = 49/297 (16%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ L FS G + S ++ RD SLGY ++N+ DAERA++T
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ + K N++I L ++ K + D FS FG I++ +V
Sbjct: 81 LNGLRLQSKTIKVSYARPSSEVIKD--ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
Query: 132 CDEHG--SRGFGFVHFETHEAAQQAINTMNG----------------------------- 160
D+ SRG F+ F+ A++AI + NG
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198
Query: 161 MLLNDRKVFVG--HFKSRREREAELGARALEFTN-------------IYVKNLPVDVDEQ 205
+ + + F G H +++R R + +G + + I++ NL D DE
Sbjct: 199 LYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEG 258
Query: 206 GLQDLFSQFGKMLSVKVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL 261
L +F FG + +VKV+RD N+ + FGFV +EEA A+ +NG + ++L
Sbjct: 259 ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKIL 315
Score = 60.1 bits (144), Expect = 6e-09
Identities = 61/223 (27%), Positives = 92/223 (41%), Gaps = 55/223 (24%)
Query: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALD 70
A+LY+ L +T+ + + FS G I++ RV D T S G A+I F + ++AE A+
Sbjct: 106 ANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAIT 165
Query: 71 TMNFEMLKG--QPIRIMWSQRDPGLRK--------------------------------- 95
+ N G +PI + ++ +P K
Sbjct: 166 SFNGHKPPGSSEPITVKFA-ANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMG 224
Query: 96 -------SGV---GN------IFIKNLEDSIDNKALYDTFSTFGNILSCKVACD--EHGS 137
SGV GN IFI NL D L+ F FG + + KV D +
Sbjct: 225 VDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKC 284
Query: 138 RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
+GFGFV +E A AI ++NG L D K+ FK+ + +
Sbjct: 285 KGFGFVTMTNYEEAAMAIASLNGYRLGD-KILQVSFKTNKSHK 326
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 121 bits (303), Expect = 2e-27
Identities = 89/337 (26%), Positives = 158/337 (46%), Gaps = 60/337 (17%)
Query: 90 DPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFET 147
D G + N+ + L ++ + L F + G I SCK+ D+ S G+GFV++
Sbjct: 30 DSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYID 89
Query: 148 HEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGL 207
+ A++AINT+NG+ L + + V + A + ++ N+YV LP + ++ L
Sbjct: 90 PKDAEKAINTLNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKEL 141
Query: 208 QDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG-------- 258
+ LFSQ+G++++ +++ D +G SR GF+ F+K EA++A+ +NG++ G
Sbjct: 142 EQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVK 201
Query: 259 ---------------------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLR 289
Y G ++ +R N L +RF M D +
Sbjct: 202 FANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMT 261
Query: 290 RYQGVN----------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGF 337
G+N ++V NL D+ L + F P+G +T+ KV+ + KGFGF
Sbjct: 262 SLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGF 321
Query: 338 VCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEER 374
V ++ +EA A+ +NG +G + L V+ K +
Sbjct: 322 VTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
Score = 84.0 bits (206), Expect = 4e-16
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ L F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
Query: 132 CDEHG--SRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 77.4 bits (189), Expect = 4e-14
Identities = 60/219 (27%), Positives = 106/219 (48%), Gaps = 28/219 (12%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ ++ L+ LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 39 TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG + + + A+ + NLYV L ++ +
Sbjct: 99 TLNGLRLQTKTIKVSYARPSSASIRD------------------ANLYVSGLPKTMTQKE 140
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRIV--GTKPLYV 365
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
Query: 366 ALAQRKEER--KAILTNQYMQRLSTMRTLSNPLLGSFQQ 402
A ++ +AIL+ Y S R PL Q+
Sbjct: 201 KFANNPSQKTNQAILSQLYQ---SPNRRYPGPLAQQAQR 236
Score = 47.8 bits (112), Expect = 3e-05
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L DR + V FK+ + +A
Sbjct: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
Score = 43.1 bits (100), Expect = 7e-04
Identities = 17/61 (27%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ ++ +A A+ ++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 73 N 73
N
Sbjct: 338 N 338
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 117 bits (292), Expect = 4e-26
Identities = 87/328 (26%), Positives = 155/328 (47%), Gaps = 61/328 (18%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ F + G+I SCK+ D+ S G+GFV++ A +AINT
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ ++ LFSQ+G++
Sbjct: 100 LNGLKLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRI 151
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGK------------------EVSG 258
++ +++ D +G SR GF+ F+K EA++A+ +NG+ + +G
Sbjct: 152 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTG 211
Query: 259 RLL-----------YAGRAQKRVER---QNELK-----RRFEQMKQDRLRRYQGVNL--- 296
+ L YAG + +R N L +RF + D + GV L
Sbjct: 212 QALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGG 271
Query: 297 --------YVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEA 346
+V NL D+ L + F P+G +T+ KV+ + KGFGFV ++ +EA
Sbjct: 272 AAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEA 331
Query: 347 TKAVTEMNGRIVGTKPLYVALAQRKEER 374
A+ +NG +G + L V+ K+ +
Sbjct: 332 AMAIASLNGYRLGERVLQVSFKTSKQHK 359
Score = 81.3 bits (199), Expect = 2e-15
Identities = 44/151 (29%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DA++A++T
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K + FS +G I++ ++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 76.6 bits (187), Expect = 6e-14
Identities = 56/213 (26%), Positives = 103/213 (48%), Gaps = 28/213 (13%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ + + LF G + S K++RD +G S +GFVN+ +A KA+
Sbjct: 39 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 98
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG ++ + + A + + NLYV L ++ +
Sbjct: 99 TLNGLKLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMSQKE 140
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
+ + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ + +P+ V
Sbjct: 141 MEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITV 200
Query: 366 ALAQRKEER--KAILTNQYMQRLSTMRTLSNPL 396
A ++ +A+LT+ Y S+ R + PL
Sbjct: 201 KFANNPSQKTGQALLTHLYQ---SSARRYAGPL 230
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACD--EHGSRGFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + +GFGFV ++ A AI ++
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L +R + V FK+ ++ +A
Sbjct: 339 NGYRLGERVLQVS-FKTSKQHKA 360
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 115 bits (288), Expect = 1e-25
Identities = 85/327 (25%), Positives = 153/327 (46%), Gaps = 60/327 (18%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 110 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 161
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG------------------ 258
++ +++ D +G SR GF+ F+K EA++A+ +NG++ SG
Sbjct: 162 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 221
Query: 259 -----------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLRRYQGVN---- 295
Y G + +R N L +RF + D + G+N
Sbjct: 222 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGH 281
Query: 296 ------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEAT 347
++V NL D+ L + F P+G + + KV+ + KGFGFV ++ +EA
Sbjct: 282 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 341
Query: 348 KAVTEMNGRIVGTKPLYVALAQRKEER 374
A+ +NG +G + L V+ K +
Sbjct: 342 MAIASLNGYRLGDRVLQVSFKTNKAHK 368
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 110 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 167
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 168 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 198
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 25/199 (12%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 49 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 108
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG + + + A + + NLYV L ++ +
Sbjct: 109 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 150
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 151 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 210
Query: 366 ALAQRKEER--KAILTNQY 382
A ++ +A+L+ Y
Sbjct: 211 KFANNPSQKSSQALLSQLY 229
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L DR + V FK+ + ++
Sbjct: 348 NGYRLGDRVLQVS-FKTNKAHKS 369
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 282 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 338
Query: 64 DAERALDTMN 73
+A A+ ++N
Sbjct: 339 EAAMAIASLN 348
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 115 bits (288), Expect = 1e-25
Identities = 85/327 (25%), Positives = 153/327 (46%), Gaps = 60/327 (18%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 107 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 158
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG------------------ 258
++ +++ D +G SR GF+ F+K EA++A+ +NG++ SG
Sbjct: 159 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 218
Query: 259 -----------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLRRYQGVN---- 295
Y G + +R N L +RF + D + G+N
Sbjct: 219 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGH 278
Query: 296 ------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEAT 347
++V NL D+ L + F P+G + + KV+ + KGFGFV ++ +EA
Sbjct: 279 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 338
Query: 348 KAVTEMNGRIVGTKPLYVALAQRKEER 374
A+ +NG +G + L V+ K +
Sbjct: 339 MAIASLNGYRLGDRVLQVSFKTNKAHK 365
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 25/199 (12%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG + + + A + + NLYV L ++ +
Sbjct: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEER--KAILTNQY 382
A ++ +A+L+ Y
Sbjct: 208 KFANNPSQKSSQALLSQLY 226
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L DR + V FK+ + ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 279 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 335
Query: 64 DAERALDTMN 73
+A A+ ++N
Sbjct: 336 EAAMAIASLN 345
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 115 bits (288), Expect = 1e-25
Identities = 85/327 (25%), Positives = 153/327 (46%), Gaps = 60/327 (18%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 124 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 175
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG------------------ 258
++ +++ D +G SR GF+ F+K EA++A+ +NG++ SG
Sbjct: 176 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 235
Query: 259 -----------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLRRYQGVN---- 295
Y G + +R N L +RF + D + G+N
Sbjct: 236 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGH 295
Query: 296 ------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEAT 347
++V NL D+ L + F P+G + + KV+ + KGFGFV ++ +EA
Sbjct: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
Query: 348 KAVTEMNGRIVGTKPLYVALAQRKEER 374
A+ +NG +G + L V+ K +
Sbjct: 356 MAIASLNGYRLGDRVLQVSFKTNKAHK 382
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 25/199 (12%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG + + + A + + NLYV L ++ +
Sbjct: 123 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 164
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
Query: 366 ALAQRKEER--KAILTNQY 382
A ++ +A+L+ Y
Sbjct: 225 KFANNPSQKSSQALLSQLY 243
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L DR + V FK+ + ++
Sbjct: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 296 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 352
Query: 64 DAERALDTMN 73
+A A+ ++N
Sbjct: 353 EAAMAIASLN 362
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 115 bits (288), Expect = 1e-25
Identities = 85/327 (25%), Positives = 153/327 (46%), Gaps = 60/327 (18%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 107 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 158
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG------------------ 258
++ +++ D +G SR GF+ F+K EA++A+ +NG++ SG
Sbjct: 159 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 218
Query: 259 -----------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLRRYQGVN---- 295
Y G + +R N L +RF + D + G+N
Sbjct: 219 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGH 278
Query: 296 ------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEAT 347
++V NL D+ L + F P+G + + KV+ + KGFGFV ++ +EA
Sbjct: 279 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 338
Query: 348 KAVTEMNGRIVGTKPLYVALAQRKEER 374
A+ +NG +G + L V+ K +
Sbjct: 339 MAIASLNGYRLGDRVLQVSFKTNKAHK 365
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 25/199 (12%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG + + + A + + NLYV L ++ +
Sbjct: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEER--KAILTNQY 382
A ++ +A+L+ Y
Sbjct: 208 KFANNPSQKSSQALLSQLY 226
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L DR + V FK+ + ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 279 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 335
Query: 64 DAERALDTMN 73
+A A+ ++N
Sbjct: 336 EAAMAIASLN 345
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 114 bits (284), Expect = 3e-25
Identities = 86/335 (25%), Positives = 153/335 (45%), Gaps = 68/335 (20%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ F + G+I SCK+ D+ S G+GFV++ A +AINT
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ ++ LFSQ+G++
Sbjct: 100 LNGLKLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRI 151
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGK------------------EVSG 258
++ +++ D +G SR GF+ F+K EA++A+ +NG+ + +G
Sbjct: 152 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTG 211
Query: 259 RLL-----------YAGRAQKRVERQN---------------ELKRRFEQMKQDRLRRYQ 292
+ L YAG + +R L RF + D +
Sbjct: 212 QALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLA 271
Query: 293 GVNL-----------YVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVC 339
GV L +V NL D+ L + F P+G +T+ KV+ + KGFGFV
Sbjct: 272 GVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVT 331
Query: 340 FSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEER 374
++ +EA A+ +NG +G + L V+ K+ +
Sbjct: 332 MTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHK 366
Score = 81.3 bits (199), Expect = 2e-15
Identities = 44/151 (29%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DA++A++T
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K + FS +G I++ ++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 76.6 bits (187), Expect = 6e-14
Identities = 56/213 (26%), Positives = 103/213 (48%), Gaps = 28/213 (13%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ + + LF G + S K++RD +G S +GFVN+ +A KA+
Sbjct: 39 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 98
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG ++ + + A + + NLYV L ++ +
Sbjct: 99 TLNGLKLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMSQKE 140
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
+ + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ + +P+ V
Sbjct: 141 MEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITV 200
Query: 366 ALAQRKEER--KAILTNQYMQRLSTMRTLSNPL 396
A ++ +A+LT+ Y S+ R + PL
Sbjct: 201 KFANNPSQKTGQALLTHLYQ---SSARRYAGPL 230
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACD--EHGSRGFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + +GFGFV ++ A AI ++
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L +R + V FK+ ++ +A
Sbjct: 346 NGYRLGERVLQVS-FKTSKQHKA 367
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 110 bits (276), Expect = 3e-24
Identities = 71/189 (37%), Positives = 103/189 (54%), Gaps = 9/189 (4%)
Query: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALD 70
A++YVG L V+E +L+E F AGP+++ + +D T + GY ++ F DA+ A+
Sbjct: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
Query: 71 TMNFEMLKGQPIRIMWSQRDPGLRKSGVG-NIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
MN L G+PIR+ ++ + VG NIFI NL+ ID K LYDTFS FG IL
Sbjct: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
Query: 130 VAC---DEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGH-FK--SRREREAEL 183
D S+G+ F++F + +A+ AI MNG L +R + V + FK S+ ER
Sbjct: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSA 190
Query: 184 GARALEFTN 192
R L N
Sbjct: 191 AERLLAAQN 199
Score = 89.0 bits (219), Expect = 1e-17
Identities = 74/273 (27%), Positives = 122/273 (44%), Gaps = 31/273 (11%)
Query: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251
+YV L V E L +LF Q G +++ + +D +G + +GFV F E+A A+ M
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
N ++ G+ + +A + + G N+++ NLD ID+ L
Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDV-----------------GANIFIGNLDPEIDEKLLY 117
Query: 312 KEFSPYGVITSA-KVMTEG--GHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA 368
FS +GVI K+M + G+SKG+ F+ F+S + + A+ MNG+ + +P+ V+ A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
Query: 369 QRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQ---AAYYGCGP 425
+K+ + ++ + NP L +P F A P P A + G G
Sbjct: 178 FKKDSK----GERHGSAAERLLAAQNP-LSQADRPHQLFADAPPPPSAPNPVVSSLGSGL 232
Query: 426 VTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPP 458
P P P S PP + P + P PP
Sbjct: 233 PPPGMPPP--GSFPPPVPPPGALPPGIPPAMPP 263
Score = 77.4 bits (189), Expect = 4e-14
Identities = 53/186 (28%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
+++ L++ + L++ F G +++ + D + G+GFV F + E A AI M
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 159 NGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKML 218
N + L + + V S + ++GA NI++ NL ++DE+ L D FS FG +L
Sbjct: 75 NMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLYDTFSAFGVIL 127
Query: 219 SV-KVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGR---LLYAGRAQKRVERQ 273
K+MRD ++G+S+ + F+NF + + A+ MNG+ + R + YA + + ER
Sbjct: 128 QTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERH 187
Query: 274 NELKRR 279
R
Sbjct: 188 GSAAER 193
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 107 bits (267), Expect = 3e-23
Identities = 92/374 (24%), Positives = 163/374 (43%), Gaps = 38/374 (10%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
+++ NL + + FS G SCK+ + + + FV F H A A+ MNG
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
Query: 161 MLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSV 220
+ ++V V + ++ + +++V +L ++ + ++ F+ FGK+
Sbjct: 71 RKILGKEVKVNWATTPSSQKKDTS----NHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
Query: 221 KVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL---YAGR---AQKRVERQ 273
+V++D +G S+ +GFV+F +A+ A+VHM G+ + GR + +A R A K +
Sbjct: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
Query: 274 NELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSK 333
N + RFE + + +Y + + D +R+ FSP+G I +V E K
Sbjct: 187 NTKQLRFEDVVNQSSPK--NCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----K 240
Query: 334 GFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLS 393
G+ FV FS+ E A A+ +NG + + + + +T + Q +
Sbjct: 241 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPD----MTKNFQQVDYSQWGQW 296
Query: 394 NPLLGSFQQPSSYFLPAMPQPPAQAAYYG-----CGPVTPTQPAPRWT----SQPPRPSC 444
+ + G+ QQ Y PP YG G P+ W +QPP+
Sbjct: 297 SQVYGNPQQYGQYMANGWQVPP--YGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQ--- 351
Query: 445 ASMVRPPVVPRRPP 458
PPV+P PP
Sbjct: 352 -GQAPPPVIP--PP 362
Score = 100 bits (249), Expect = 4e-21
Identities = 71/270 (26%), Positives = 127/270 (47%), Gaps = 29/270 (10%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+LYVG+L DVTE ++ + FS GP S ++ + + Y ++ F + DA AL
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA 67
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGN---IFIKNLEDSIDNKALYDTFSTFGNILSC 128
MN + G+ +++ W+ P +K N +F+ +L I + + F+ FG I
Sbjct: 68 MNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
Query: 129 KVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRR----EREAE 182
+V D S+G+GFV F A+ AI M G L R++ ++ +R+ + E
Sbjct: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRT-NWATRKPPAPKSTQE 185
Query: 183 LGARALEFTN-----------IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSR 231
+ L F + +Y + + +Q ++ FS FG+++ ++V +
Sbjct: 186 NNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKG---- 241
Query: 232 CFGFVNFEKHEEAQKAVVHMNGKEVSGRLL 261
+ FV F HE A A+V +NG + G ++
Sbjct: 242 -YSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
++Y G + +T+ ++ + FSP G I+ IRV + GY+++ F A A+ +
Sbjct: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 259
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKS 96
+N ++G ++ W + P + K+
Sbjct: 260 VNGTTIEGHVVKCYWGKESPDMTKN 284
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 105 bits (263), Expect = 9e-23
Identities = 86/341 (25%), Positives = 155/341 (45%), Gaps = 74/341 (21%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 107 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 158
Query: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNG-------------------KEVS 257
++ +++ D +G SR GF+ F+K EA++A+ +NG ++ S
Sbjct: 159 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 218
Query: 258 GRLL----------YAGRAQKRVERQN---------ELKR-------------RFEQMKQ 285
LL Y G + +R +KR RF +
Sbjct: 219 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITI 278
Query: 286 DRLRRYQGVNL----------YVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSK-- 333
D + G+N+ +V NL D+ L + F P+G + + KV+ + +K
Sbjct: 279 DGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCK 338
Query: 334 GFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEER 374
GFGFV ++ +EA A+ +NG +G + L V+ K +
Sbjct: 339 GFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHK 379
Score = 82.4 bits (202), Expect = 1e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
D+ SRG GF+ F+ A++AI +NG
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 77.0 bits (188), Expect = 5e-14
Identities = 65/253 (25%), Positives = 116/253 (45%), Gaps = 31/253 (12%)
Query: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
+NG + + + A + + NLYV L ++ +
Sbjct: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEER--KAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYGC 423
A ++ +A+L+ Y S R PL Q + L +
Sbjct: 208 KFANNPSQKSSQALLSQLYQ---SPNRRYPGPL---HHQAQRFRLDNLLNMAYGVKRLMS 261
Query: 424 GPVTPTQPAPRWT 436
GPV P+ PR++
Sbjct: 262 GPVPPSACPPRFS 274
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 159 NGMLLNDRKVFVGHFKSRREREA 181
NG L DR + V FK+ + ++
Sbjct: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 293 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 349
Query: 64 DAERALDTMN 73
+A A+ ++N
Sbjct: 350 EAAMAIASLN 359
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 104 bits (260), Expect = 2e-22
Identities = 78/291 (26%), Positives = 138/291 (47%), Gaps = 35/291 (12%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+LYVG+L DVTEA++ + FS GP + ++ D A Y ++ F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAA 65
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGN---IFIKNLEDSIDNKALYDTFSTFGNILSC 128
MN + G+ +++ W+ P +K N +F+ +L I + + F+ FG I
Sbjct: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 129 KVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRR----EREAE 182
+V D S+G+GFV F A+ AI M G L R++ ++ +R+ + E
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRT-NWATRKPPAPKSTYE 183
Query: 183 LGARALEFTNIYVKNLPVD-----------VDEQGLQDLFSQFGKMLSVKVMRDNSGHSR 231
+ L + + ++ P + + EQ ++ FS FG+++ ++V D
Sbjct: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKG---- 239
Query: 232 CFGFVNFEKHEEAQKAVVHMNGKEVSGRLL--YAGRAQ----KRVERQNEL 276
+ FV F HE A A+V +NG + G ++ Y G+ V++QN++
Sbjct: 240 -YSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQI 289
Score = 95.1 bits (235), Expect = 2e-19
Identities = 62/263 (23%), Positives = 125/263 (47%), Gaps = 13/263 (4%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
+++ NL + + FS G +CK+ D G+ + FV F H A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 161 MLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSV 220
+ ++V V + ++ + +++V +L ++ + ++ F+ FG++
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTS----NHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 221 KVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRA-QKRVERQNELKR 278
+V++D +G S+ +GFV+F +A+ A+ M G+ + GR + A +K ++ +
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
Query: 279 RFEQMKQDRLRRY---QGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGF 335
+Q+ D + +Y + + + +R+ FSP+G I +V + KG+
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
FV F+S E A A+ +NG +
Sbjct: 241 SFVRFNSHESAAHAIVSVNGTTI 263
Score = 82.4 bits (202), Expect = 1e-15
Identities = 52/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
+YV NL DV E + LFSQ G + K++ D +G+ + FV F +H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 253 GKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRK 312
G+++ G+ + A ++ + F +++V +L I + ++
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
Query: 313 EFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370
F+P+G I+ A+V+ + G SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
Query: 371 K 371
K
Sbjct: 174 K 174
>gi|239753150 PREDICTED: similar to poly(A) binding protein,
cytoplasmic 1 [Homo sapiens]
Length = 94
Score = 103 bits (258), Expect = 4e-22
Identities = 53/73 (72%), Positives = 62/73 (84%)
Query: 535 MLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKID 594
MLA+AP EQK+++GERL+PLI +H LAGKITGM LE DNSELL MLESPESLH+K+
Sbjct: 1 MLASAPPQEQKRILGERLFPLIQAMHPTLAGKITGMWLETDNSELLHMLESPESLHSKVV 60
Query: 595 EAVAVLQAHQAME 607
EAVAVLQAH+A E
Sbjct: 61 EAVAVLQAHRAKE 73
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 102 bits (253), Expect = 1e-21
Identities = 96/391 (24%), Positives = 166/391 (42%), Gaps = 55/391 (14%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR------GFG-----------FV 143
+++ NL + + FS G SCK+ ++ SR GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 144 HFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVD 203
F H A A+ MNG + ++V V + ++ + +++V +L ++
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTS----NHFHVFVGDLSPEIT 126
Query: 204 EQGLQDLFSQFGKMLSVKVMRDNS-GHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL- 261
+ ++ F+ FGK+ +V++D + G S+ +GFV+F +A+ A+VHM G+ + GR +
Sbjct: 127 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR 186
Query: 262 --YAGR---AQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSP 316
+A R A K + N + RFE + + +Y + + D +R+ FSP
Sbjct: 187 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPK--NCTVYCGGIASGLTDQLMRQTFSP 244
Query: 317 YGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKA 376
+G I +V E KG+ FV FS+ E A A+ +NG + + + +
Sbjct: 245 FGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPD--- 297
Query: 377 ILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYG-----CGPVTPTQP 431
+T + Q + + + G+ QQ Y PP YG G P
Sbjct: 298 -MTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPP--YGVYGQPWNQQGFGVDQSP 354
Query: 432 APRWT----SQPPRPSCASMVRPPVVPRRPP 458
+ W +QPP+ PPV+P PP
Sbjct: 355 SAAWMGGFGAQPPQ----GQAPPPVIP--PP 379
Score = 97.4 bits (241), Expect = 3e-20
Identities = 72/285 (25%), Positives = 128/285 (44%), Gaps = 42/285 (14%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLG---------------YAY 56
+LYVG+L DVTE ++ + FS GP S ++ + R + Y +
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69
Query: 57 INFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGN---IFIKNLEDSIDNK 113
+ F + DA AL MN + G+ +++ W+ P +K N +F+ +L I +
Sbjct: 70 VEFYEHRDAAAALAAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTE 128
Query: 114 ALYDTFSTFGNILSCKVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVG 171
+ F+ FG I +V D S+G+GFV F A+ AI M G L R++
Sbjct: 129 DIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRT- 187
Query: 172 HFKSRR----EREAELGARALEFTN-----------IYVKNLPVDVDEQGLQDLFSQFGK 216
++ +R+ + E + L F + +Y + + +Q ++ FS FG+
Sbjct: 188 NWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQ 247
Query: 217 MLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL 261
++ ++V + + FV F HE A A+V +NG + G ++
Sbjct: 248 IMEIRVFPEKG-----YSFVRFSTHESAAHAIVSVNGTTIEGHVV 287
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
++Y G + +T+ ++ + FSP G I+ IRV + GY+++ F A A+ +
Sbjct: 223 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 276
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKS 96
+N ++G ++ W + P + K+
Sbjct: 277 VNGTTIEGHVVKCYWGKESPDMTKN 301
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 99.4 bits (246), Expect = 9e-21
Identities = 76/301 (25%), Positives = 137/301 (45%), Gaps = 44/301 (14%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+LYVG+L DVTEA++ + FS GP + ++ D A Y ++ F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAA 65
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVG-------------NIFIKNLEDSIDNKALYDT 118
MN + G+ +++ W+ +K ++F+ +L I + +
Sbjct: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
Query: 119 FSTFGNILSCKVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSR 176
F+ FG I +V D S+G+GFV F A+ AI M G L R++ ++ +R
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRT-NWATR 184
Query: 177 R----EREAELGARALEFTNIYVKNLPVD-----------VDEQGLQDLFSQFGKMLSVK 221
+ + E + L + + ++ P + + EQ ++ FS FG+++ ++
Sbjct: 185 KPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIR 244
Query: 222 VMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL--YAGRAQ----KRVERQNE 275
V D + FV F HE A A+V +NG + G ++ Y G+ V++QN+
Sbjct: 245 VFPDKG-----YSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQ 299
Query: 276 L 276
+
Sbjct: 300 I 300
Score = 96.7 bits (239), Expect = 6e-20
Identities = 63/270 (23%), Positives = 129/270 (47%), Gaps = 16/270 (5%)
Query: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
+++ NL + + FS G +CK+ D G+ + FV F H A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 161 MLLNDRKVFVGHFKSRREREAELGA-------RALEFTNIYVKNLPVDVDEQGLQDLFSQ 213
+ ++V V + ++ + + R+ + +++V +L ++ + ++ F+
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
Query: 214 FGKMLSVKVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRA-QKRVE 271
FG++ +V++D +G S+ +GFV+F +A+ A+ M G+ + GR + A +K
Sbjct: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
Query: 272 RQNELKRRFEQMKQDRLRRY---QGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE 328
++ + +Q+ D + +Y + + + +R+ FSP+G I +V +
Sbjct: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
Query: 329 GGHSKGFGFVCFSSPEEATKAVTEMNGRIV 358
KG+ FV F+S E A A+ +NG +
Sbjct: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
Score = 82.4 bits (202), Expect = 1e-15
Identities = 53/181 (29%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
+YV NL DV E + LFSQ G + K++ D +G+ + FV F +H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 253 GKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRK 312
G+++ G+ + A ++ + Q R +++V +L I + ++
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQ---RSQDHFHVFVGDLSPEITTEDIKA 124
Query: 313 EFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370
F+P+G I+ A+V+ + G SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
Query: 371 K 371
K
Sbjct: 185 K 185
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 92.4 bits (228), Expect = 1e-18
Identities = 76/324 (23%), Positives = 144/324 (44%), Gaps = 31/324 (9%)
Query: 45 DVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIK 104
DV + + Y++F+ D E+AL+ ++ G I++ + ++ + K
Sbjct: 340 DVRIGMTRKFGYVDFESAEDLEKALELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAK 398
Query: 105 NLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLN 164
NL + L + F I ++ + S+G ++ F+T A++ G ++
Sbjct: 399 NLPYKVTQDELKEVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEID 455
Query: 165 DRKVFVGHFKSRREREAELGAR----ALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSV 220
R + + + + + + G + + E + + NL E+ LQ++F K +
Sbjct: 456 GRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFE---KATFI 512
Query: 221 KVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRF 280
KV ++ +G S+ + F+ F E+A++A+ N +E+ GR + R+E Q
Sbjct: 513 KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQG------ 559
Query: 281 EQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMT--EGGHSKGFGFV 338
R L+VK L + ++ L++ F A+++T E G SKGFGFV
Sbjct: 560 -PRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDG---SVRARIVTDRETGSSKGFGFV 615
Query: 339 CFSSPEEATKAVTEM-NGRIVGTK 361
F+S E+A A M +G I G K
Sbjct: 616 DFNSEEDAKAAKEAMEDGEIDGNK 639
Score = 61.2 bits (147), Expect = 3e-09
Identities = 55/235 (23%), Positives = 101/235 (42%), Gaps = 27/235 (11%)
Query: 137 SRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVK 196
+R FG+V FE+ E ++A+ L KVF K + + + + + + K
Sbjct: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
Query: 197 NLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEV 256
NLP V + L+++F ++ V G S+ ++ F+ +A+K G E+
Sbjct: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
Query: 257 SGR---LLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKE 313
GR L Y G + + + + + L + NL S ++ L++
Sbjct: 455 DGRSISLYYTGEKGQNQDYRGGKNSTWSG---------ESKTLVLSNLSYSATEETLQEV 505
Query: 314 FSPYGVITSAKV-MTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVAL 367
F T KV + G SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 506 FEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/170 (29%), Positives = 82/170 (48%), Gaps = 9/170 (5%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+L + +L TE L E F A I+V ++ +S GYA+I F DA+ AL++
Sbjct: 487 TLVLSNLSYSATEETLQEVFEKA---TFIKVPQN-QNGKSKGYAFIEFASFEDAKEALNS 542
Query: 72 MNFEMLKGQPIRI--MWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
N ++G+ IR+ + P R +F+K L + + L ++F G++ +
Sbjct: 543 CNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARI 600
Query: 130 VACDEHGS-RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRE 178
V E GS +GFGFV F + E A+ A M ++ KV + K + E
Sbjct: 601 VTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 20/164 (12%)
Query: 192 NIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHM 251
N++V NL + L+ S + V+ G +R FG+V+FE E+ +KA + +
Sbjct: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKA-LEL 366
Query: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
G +V G NE+K + K + R L KNL + D+L+
Sbjct: 367 TGLKVFG---------------NEIKLEKPKGKDSKKER-DARTLLAKNLPYKVTQDELK 410
Query: 312 KEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNG 355
+ F I +++++ G SKG ++ F + +A K E G
Sbjct: 411 EVFEDAAEI---RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQG 451
Score = 39.3 bits (90), Expect = 0.011
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Query: 9 PLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERA 68
P +L+V L D TE L E F + + R+ D T S G+ +++F DA+ A
Sbjct: 570 PSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEEDAKAA 626
Query: 69 LDTMNFEMLKGQPIRIMWSQ 88
+ M + G + + W++
Sbjct: 627 KEAMEDGEIDGNKVTLDWAK 646
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 90.5 bits (223), Expect = 4e-18
Identities = 79/267 (29%), Positives = 134/267 (50%), Gaps = 27/267 (10%)
Query: 11 ASLYVGDLHPDVTEAMLY-EKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
A L + L P+ EA+ +K++ I S+ V + +A ++ QQ + + A
Sbjct: 9 AKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQ---------QQLTNLQMAA 59
Query: 70 DTMNF-EMLKGQPIRIMWSQRDPGLR---KSGVGNIFIKNLEDSIDNKALYDTFSTFGNI 125
TM F + L P++ M +QR L + VG+I+ + ED+I F+ FG I
Sbjct: 60 VTMGFGDPLS--PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQ-----AFAPFGPI 112
Query: 126 LSCKVACDE--HGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREA-- 181
S ++ D +GF FV +E EAAQ A+ MN ++L R + VG + + +
Sbjct: 113 KSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPII 172
Query: 182 -ELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRD-NSGHSRCFGFVNFE 239
+L A F IYV ++ D+ + ++ +F FGK+ S + RD +G + +GF+ +E
Sbjct: 173 DQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYE 232
Query: 240 KHEEAQKAVVHMNGKEVSGRLLYAGRA 266
K + +Q AV MN ++ G+ L G+A
Sbjct: 233 KAQSSQDAVSSMNLFDLGGQYLRVGKA 259
Score = 79.0 bits (193), Expect = 1e-14
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 11/173 (6%)
Query: 10 LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
+ +YVG ++ ++ E + + F+P GPI SI + D T + G+A++ ++ P A+ AL
Sbjct: 85 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 144
Query: 70 DTMNFEMLKGQPIRI----MWSQRDPGL-----RKSGVGNIFIKNLEDSIDNKALYDTFS 120
+ MN ML G+ I++ Q P + I++ ++ + + + F
Sbjct: 145 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 204
Query: 121 TFGNILSCKVACDEHGS--RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVG 171
FG I SC +A D +G+GF+ +E +++Q A+++MN L + + VG
Sbjct: 205 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 257
Score = 63.5 bits (153), Expect = 5e-10
Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 12/180 (6%)
Query: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251
+YV ++ ++ E ++ F+ FG + S+ + D+ + + F FV +E E AQ A+ M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
N + GR + GR + Q + + E+ + +YV ++ + DD ++
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 200
Query: 312 KEFSPYGVITS---AKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA 368
F +G I S A+ T G H KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 201 SVFEAFGKIKSCTLARDPTTGKH-KGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 259
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 90.5 bits (223), Expect = 4e-18
Identities = 79/267 (29%), Positives = 134/267 (50%), Gaps = 27/267 (10%)
Query: 11 ASLYVGDLHPDVTEAMLY-EKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
A L + L P+ EA+ +K++ I S+ V + +A ++ QQ + + A
Sbjct: 52 AKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQ---------QQLTNLQMAA 102
Query: 70 DTMNF-EMLKGQPIRIMWSQRDPGLR---KSGVGNIFIKNLEDSIDNKALYDTFSTFGNI 125
TM F + L P++ M +QR L + VG+I+ + ED+I F+ FG I
Sbjct: 103 VTMGFGDPLS--PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQ-----AFAPFGPI 155
Query: 126 LSCKVACDE--HGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREA-- 181
S ++ D +GF FV +E EAAQ A+ MN ++L R + VG + + +
Sbjct: 156 KSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPII 215
Query: 182 -ELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRD-NSGHSRCFGFVNFE 239
+L A F IYV ++ D+ + ++ +F FGK+ S + RD +G + +GF+ +E
Sbjct: 216 DQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYE 275
Query: 240 KHEEAQKAVVHMNGKEVSGRLLYAGRA 266
K + +Q AV MN ++ G+ L G+A
Sbjct: 276 KAQSSQDAVSSMNLFDLGGQYLRVGKA 302
Score = 79.0 bits (193), Expect = 1e-14
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 11/173 (6%)
Query: 10 LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
+ +YVG ++ ++ E + + F+P GPI SI + D T + G+A++ ++ P A+ AL
Sbjct: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
Query: 70 DTMNFEMLKGQPIRI----MWSQRDPGL-----RKSGVGNIFIKNLEDSIDNKALYDTFS 120
+ MN ML G+ I++ Q P + I++ ++ + + + F
Sbjct: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
Query: 121 TFGNILSCKVACDEHGS--RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVG 171
FG I SC +A D +G+GF+ +E +++Q A+++MN L + + VG
Sbjct: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 300
Score = 63.5 bits (153), Expect = 5e-10
Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 12/180 (6%)
Query: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251
+YV ++ ++ E ++ F+ FG + S+ + D+ + + F FV +E E AQ A+ M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
N + GR + GR + Q + + E+ + +YV ++ + DD ++
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 243
Query: 312 KEFSPYGVITS---AKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA 368
F +G I S A+ T G H KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 244 SVFEAFGKIKSCTLARDPTTGKH-KGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 87.8 bits (216), Expect = 3e-17
Identities = 46/159 (28%), Positives = 84/159 (52%), Gaps = 17/159 (10%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N++I+ L+ ++ L +G I+S K D+ + +G+GFV F++ AAQ+A+
Sbjct: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+ + ++E++ TN+Y+ NLP+ +DEQ L+ + FG++
Sbjct: 117 LKASGVQ------AQMAKQQEQDP---------TNLYISNLPLSMDEQELEGMLKPFGQV 161
Query: 218 LSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEV 256
+S +++RD SG SR GF E E+ + + H NGK +
Sbjct: 162 ISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYI 200
Score = 77.4 bits (189), Expect = 4e-14
Identities = 50/181 (27%), Positives = 84/181 (46%), Gaps = 27/181 (14%)
Query: 184 GARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHS-RCFGFVNFEKHE 242
G L TN+Y++ L +Q L L +GK++S K + D + + + +GFV+F+
Sbjct: 49 GNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPS 108
Query: 243 EAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLD 302
AQKAV + V ++ +Q +QD NLY+ NL
Sbjct: 109 AAQKAVTALKASGVQAQMA-------------------KQQEQDP------TNLYISNLP 143
Query: 303 DSIDDDKLRKEFSPYGVITSAKVMTE-GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTK 361
S+D+ +L P+G + S +++ + G S+G GF S E+ +T NG+ + T
Sbjct: 144 LSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEAIITHFNGKYIKTP 203
Query: 362 P 362
P
Sbjct: 204 P 204
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/150 (28%), Positives = 73/150 (48%), Gaps = 10/150 (6%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
+LY+ L P T+ L + P G I+S + D T + GY +++F P+ A++A+
Sbjct: 57 NLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTA 116
Query: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
+ ++ Q + ++DP N++I NL S+D + L FG ++S ++
Sbjct: 117 LKASGVQAQMAK--QQEQDP-------TNLYISNLPLSMDEQELEGMLKPFGQVISTRIL 167
Query: 132 CDEHG-SRGFGFVHFETHEAAQQAINTMNG 160
D G SRG GF E+ E + I NG
Sbjct: 168 RDTSGTSRGVGFARMESTEKCEAIITHFNG 197
>gi|4506447 RNA binding motif, single stranded interacting protein 1
isoform c [Homo sapiens]
Length = 403
Score = 86.3 bits (212), Expect = 8e-17
Identities = 46/157 (29%), Positives = 85/157 (54%), Gaps = 17/157 (10%)
Query: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
N++I+ L ++ L +G I+S K D+ + +G+GFV F++ AAQ+A++
Sbjct: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
Query: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
+ + ++E++ TN+Y+ NLP+ +DEQ L+++ FG++
Sbjct: 123 LKASGVQ------AQMAKQQEQDP---------TNLYISNLPLSMDEQELENMLKPFGQV 167
Query: 218 LSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGK 254
+S +++RD+SG SR GF E E+ + + H NGK
Sbjct: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGK 204
Score = 77.8 bits (190), Expect = 3e-14
Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 27/177 (15%)
Query: 188 LEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHS-RCFGFVNFEKHEEAQK 246
L TN+Y++ LP +Q L L +GK++S K + D + + + +GFV+F+ AQK
Sbjct: 59 LSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQK 118
Query: 247 AVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSID 306
AV + V ++ +Q +QD NLY+ NL S+D
Sbjct: 119 AVSALKASGVQAQMA-------------------KQQEQD------PTNLYISNLPLSMD 153
Query: 307 DDKLRKEFSPYGVITSAKVMTE-GGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKP 362
+ +L P+G + S +++ + G S+G GF S E+ + NG+ + T P
Sbjct: 154 EQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPP 210
Score = 75.9 bits (185), Expect = 1e-13
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 13/166 (7%)
Query: 2 NASGSGYPLAS---LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYIN 58
++S SG+ S LY+ L P T+ L + P G I+S + D T + GY +++
Sbjct: 50 SSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVD 109
Query: 59 FQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDT 118
F PA A++A+ + ++ Q + ++DP N++I NL S+D + L +
Sbjct: 110 FDSPAAAQKAVSALKASGVQAQMAK--QQEQDP-------TNLYISNLPLSMDEQELENM 160
Query: 119 FSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMNGMLL 163
FG ++S ++ D G SRG GF E+ E + I NG +
Sbjct: 161 LKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFI 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,484,204
Number of Sequences: 37866
Number of extensions: 1222831
Number of successful extensions: 8570
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 342
Number of HSP's that attempted gapping in prelim test: 5753
Number of HSP's gapped (non-prelim): 2071
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.