BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|183979975 claudin 19 isoform b [Homo sapiens] (211 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|183979975 claudin 19 isoform b [Homo sapiens] 427 e-120 gi|183979973 claudin 19 isoform a [Homo sapiens] 424 e-119 gi|10863887 claudin 1 [Homo sapiens] 260 5e-70 gi|153792186 claudin 7 [Homo sapiens] 249 1e-66 gi|11141861 claudin 9 [Homo sapiens] 194 6e-50 gi|4502877 claudin 4 [Homo sapiens] 193 1e-49 gi|4502875 claudin 3 [Homo sapiens] 192 1e-49 gi|195947374 claudin 5 [Homo sapiens] 187 6e-48 gi|195947372 claudin 5 [Homo sapiens] 187 6e-48 gi|153792768 claudin 6 [Homo sapiens] 184 4e-47 gi|225703142 claudin 14 [Homo sapiens] 184 6e-47 gi|21536294 claudin 14 [Homo sapiens] 184 6e-47 gi|225703138 claudin 14 [Homo sapiens] 184 6e-47 gi|6912314 claudin 14 [Homo sapiens] 184 6e-47 gi|225703140 claudin 14 [Homo sapiens] 184 6e-47 gi|9966781 claudin 2 [Homo sapiens] 168 4e-42 gi|6912316 claudin 17 [Homo sapiens] 164 4e-41 gi|40788011 claudin 8 [Homo sapiens] 161 4e-40 gi|7656981 claudin 15 [Homo sapiens] 161 4e-40 gi|5921465 claudin 10 isoform b [Homo sapiens] 160 1e-39 gi|33598916 claudin 10 isoform a [Homo sapiens] 152 2e-37 gi|50345279 claudin 18 isoform 2 [Homo sapiens] 147 6e-36 gi|47716519 claudin 20 [Homo sapiens] 146 1e-35 gi|7705961 claudin 18 isoform 1 [Homo sapiens] 144 5e-35 gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 135 2e-32 gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 118 4e-27 gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 116 1e-26 gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 116 1e-26 gi|162417973 claudin 22 [Homo sapiens] 114 5e-26 gi|10938016 claudin 11 [Homo sapiens] 105 4e-23 >gi|183979975 claudin 19 isoform b [Homo sapiens] Length = 211 Score = 427 bits (1099), Expect = e-120 Identities = 211/211 (100%), Positives = 211/211 (100%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211 >gi|183979973 claudin 19 isoform a [Homo sapiens] Length = 224 Score = 424 bits (1089), Expect = e-119 Identities = 210/211 (99%), Positives = 210/211 (99%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211 FLCCTCPEPERPNSSPQPYRPGPSAAARE V Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPV 211 >gi|10863887 claudin 1 [Homo sapiens] Length = 211 Score = 260 bits (665), Expect = 5e-70 Identities = 121/212 (57%), Positives = 159/212 (75%), Gaps = 2/212 (0%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MAN+GLQLLG+ LA GW+G I STALPQW+ SYAGD I+TA +YEGLWMSC SQSTG Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Q+QCK++DSLL L +Q+ RALMVV +LLG +A+ ++ VGMKC + + + + K R+A+ Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GGA+F+LAGL L A +WY + QEF++P TPVNARYEFG ALF GWA+A L +LGG+ Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180 Query: 181 FLCCTCPEPERPNSSPQPY-RPGPSAAAREYV 211 LCC+CP +P+PY +P PS + ++YV Sbjct: 181 LLCCSCPRKTTSYPTPRPYPKPAPS-SGKDYV 211 >gi|153792186 claudin 7 [Homo sapiens] Length = 211 Score = 249 bits (636), Expect = 1e-66 Identities = 113/211 (53%), Positives = 153/211 (72%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MANSGLQLLG+ +AL GWVG++A TA+PQW+ SSYAGD IITA +Y+GLWM C +QSTG Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 + CK+YDS+LAL +Q+ RALMVV+++LGF+AM ++ +GMKCTR G + + K R+A+ Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG +FI+AGL L A SWY + +F+NP P N +YEFGPA+F+GWA + L +LGG+ Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180 Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211 L C+CP E P S +++EYV Sbjct: 181 LLSCSCPGNESKAGYRVPRSYPKSNSSKEYV 211 >gi|11141861 claudin 9 [Homo sapiens] Length = 217 Score = 194 bits (492), Expect = 6e-50 Identities = 98/218 (44%), Positives = 142/218 (65%), Gaps = 8/218 (3%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++GL+LLG LA+ GW+G + S ALP WK +++ G++I+ A ++EGLWMSC QSTG Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Q+QCK+YDSLLAL +Q+ARAL V+A+LL + +++++ G +CT + AK R+ + Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEG-AKARIVL 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 G + +LAG+ L V W A + Q+F+NP + E G +L++GWA+A L +LGG Sbjct: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179 Query: 181 FLCCTCPEP--ERPNSSPQPYR-PGPSAAA----REYV 211 LCCTCP P ERP Y P S A+ R+YV Sbjct: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217 >gi|4502877 claudin 4 [Homo sapiens] Length = 209 Score = 193 bits (490), Expect = 1e-49 Identities = 93/211 (44%), Positives = 137/211 (64%), Gaps = 2/211 (0%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA+ GLQ++G LA+ GW+ ++ ALP W+ +++ G I+T+ ++EGLWM+C QSTG Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Q+QCK+YDSLLAL +Q+ARAL+++++++ + ++LSVVG KCT + AK + I Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDES-AKAKTMI 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 G +F+LAGL + VSW A + Q+F+NP + E G +L+VGWA++GL +LGG Sbjct: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179 Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211 LCC CP P Y SAAA YV Sbjct: 180 LLCCNCP-PRTDKPYSAKYSAARSAAASNYV 209 >gi|4502875 claudin 3 [Homo sapiens] Length = 220 Score = 192 bits (489), Expect = 1e-49 Identities = 94/207 (45%), Positives = 136/207 (65%), Gaps = 6/207 (2%) Query: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64 GL++ G LA+ GW+G I ALP W+ S++ G IIT+ ++EGLWM+C QSTGQ+QC Sbjct: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63 Query: 65 KLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGA 124 K+YDSLLAL +Q+ARAL+VVA+LL +++++VG +CT + AK ++ I G Sbjct: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122 Query: 125 LFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCC 184 LF+LA L TL VSW A + ++F+NP P + E G L+VGWA+A L +LGG+ LCC Sbjct: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182 Query: 185 TCPEPERPNSSPQ-----PYRPGPSAA 206 +CP E+ ++ + P GP A+ Sbjct: 183 SCPPREKKYTATKVVYSAPRSTGPGAS 209 >gi|195947374 claudin 5 [Homo sapiens] Length = 303 Score = 187 bits (475), Expect = 6e-48 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 +QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+ Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 Query: 181 FLCCTC------PEPERPNSSPQPYRP 201 LCC P+ P P RP Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291 >gi|195947372 claudin 5 [Homo sapiens] Length = 303 Score = 187 bits (475), Expect = 6e-48 Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 +QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+ Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264 Query: 181 FLCCTC------PEPERPNSSPQPYRP 201 LCC P+ P P RP Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291 >gi|153792768 claudin 6 [Homo sapiens] Length = 220 Score = 184 bits (468), Expect = 4e-47 Identities = 89/207 (42%), Positives = 133/207 (64%), Gaps = 1/207 (0%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++G+Q+LG L L GWV + S ALP WK +++ G++I+ A ++EGLWMSC QSTG Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 Q+QCK+YDSLLAL +Q+ARAL V+A+L+ +++ + G KCT + +K R+ + Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 G +F+++G+ TL V W A + ++F+NP + E G +L++GWA++GL +LGG Sbjct: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179 Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAA 207 LCCTCP S R SA A Sbjct: 180 LLCCTCPSGGSQGPSHYMARYSTSAPA 206 >gi|225703142 claudin 14 [Homo sapiens] Length = 239 Score = 184 bits (466), Expect = 6e-47 Identities = 92/198 (46%), Positives = 130/198 (65%), Gaps = 3/198 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+ Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179 Query: 181 FLCCTCPE--PERPNSSP 196 LC +C + P RP +P Sbjct: 180 LLCLSCQDEAPYRPYQAP 197 >gi|21536294 claudin 14 [Homo sapiens] Length = 239 Score = 184 bits (466), Expect = 6e-47 Identities = 92/198 (46%), Positives = 130/198 (65%), Gaps = 3/198 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+ Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179 Query: 181 FLCCTCPE--PERPNSSP 196 LC +C + P RP +P Sbjct: 180 LLCLSCQDEAPYRPYQAP 197 >gi|225703138 claudin 14 [Homo sapiens] Length = 239 Score = 184 bits (466), Expect = 6e-47 Identities = 92/198 (46%), Positives = 130/198 (65%), Gaps = 3/198 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+ Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179 Query: 181 FLCCTCPE--PERPNSSP 196 LC +C + P RP +P Sbjct: 180 LLCLSCQDEAPYRPYQAP 197 >gi|6912314 claudin 14 [Homo sapiens] Length = 239 Score = 184 bits (466), Expect = 6e-47 Identities = 92/198 (46%), Positives = 130/198 (65%), Gaps = 3/198 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+ Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179 Query: 181 FLCCTCPE--PERPNSSP 196 LC +C + P RP +P Sbjct: 180 LLCLSCQDEAPYRPYQAP 197 >gi|225703140 claudin 14 [Homo sapiens] Length = 239 Score = 184 bits (466), Expect = 6e-47 Identities = 92/198 (46%), Positives = 130/198 (65%), Gaps = 3/198 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+ Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179 Query: 181 FLCCTCPE--PERPNSSP 196 LC +C + P RP +P Sbjct: 180 LLCLSCQDEAPYRPYQAP 197 >gi|9966781 claudin 2 [Homo sapiens] Length = 230 Score = 168 bits (425), Expect = 4e-42 Identities = 89/215 (41%), Positives = 129/215 (60%), Gaps = 15/215 (6%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA+ GLQL+GY L L G +G + + LP WK SSY G +I+TAVG +GLWM CA+ STG Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 QC +Y +LL L IQ+A+A+MV + + +A ++SVVGM+CT V AK RVA+ Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCT-VFCQESRAKDRVAV 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 AGG FIL GL V+W + ++F++P P + ++E G AL++G S+ +++ G Sbjct: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179 Query: 181 FLCCTC--------------PEPERPNSSPQPYRP 201 LC +C +P SSP+P +P Sbjct: 180 ILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQP 214 >gi|6912316 claudin 17 [Homo sapiens] Length = 224 Score = 164 bits (416), Expect = 4e-41 Identities = 85/200 (42%), Positives = 120/200 (60%), Gaps = 2/200 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA LQ+ G L G VG +A+T LPQW+ S++ G II L+EGLWM+C Q+ Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 ++QCK Y SLLAL +++ARALM VAV L +A+++ + GMK + SN AK + Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 G LFIL G+ L VSW A ++ ++F+NP+ + + E G ALF+GWASA + +GG Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180 Query: 181 FLC--CTCPEPERPNSSPQP 198 LC C C ++ P P Sbjct: 181 LLCGFCCCNRKKQGYRYPVP 200 >gi|40788011 claudin 8 [Homo sapiens] Length = 225 Score = 161 bits (407), Expect = 4e-40 Identities = 72/184 (39%), Positives = 114/184 (61%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA L++ G FL G VG +A T +PQW+ S++ + I+ +EGLWM+C Q+ Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 ++QCK+YDSLLAL +Q+AR LM A ++ F+A +++++GMKCTR N K + + Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 G +FI+ G+ L VSW A + ++F+N V + E G AL++GW +A + ++GG+ Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180 Query: 181 FLCC 184 CC Sbjct: 181 LFCC 184 >gi|7656981 claudin 15 [Homo sapiens] Length = 228 Score = 161 bits (407), Expect = 4e-40 Identities = 79/198 (39%), Positives = 127/198 (64%), Gaps = 5/198 (2%) Query: 6 LQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCK 65 ++ G+F+A G + + + W+ S+ G+ +IT ++E LW SCA+ S G C Sbjct: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN-VITTNTIFENLWFSCATDSLGVYNCW 63 Query: 66 LYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGAL 125 + S+LAL G+IQ+ RALM+ A+LLGF+ ++L + G++CT +G K ++A GAL Sbjct: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123 Query: 126 FILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC-- 183 ILAG+C + A+SWYA +T++FF+P P +YE GPAL++GW+++ +++LGG LC Sbjct: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182 Query: 184 CTCPEPERPNSSP-QPYR 200 C C E P +S +PY+ Sbjct: 183 CCCGSDEDPAASARRPYQ 200 >gi|5921465 claudin 10 isoform b [Homo sapiens] Length = 228 Score = 160 bits (404), Expect = 1e-39 Identities = 78/183 (42%), Positives = 116/183 (63%), Gaps = 3/183 (1%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++ +++ + +++ GWV + ++ WK S+ G I TA + LW +C + STG Sbjct: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTAT-YWANLWKACVTDSTG 59 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 CK + S+LALDG+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A Sbjct: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIAC 118 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 G +FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG Sbjct: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177 Query: 181 FLC 183 C Sbjct: 178 IFC 180 >gi|33598916 claudin 10 isoform a [Homo sapiens] Length = 226 Score = 152 bits (384), Expect = 2e-37 Identities = 74/180 (41%), Positives = 114/180 (63%), Gaps = 3/180 (1%) Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63 S Q+ +GG+ ++A+T +WK ++ A ++ITA +Y+GLWM+CA + G Sbjct: 2 SRAQIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGNALGSFH 60 Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123 C+ + ++ + G+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A G Sbjct: 61 CRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAG 119 Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC 183 +FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG C Sbjct: 120 IVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFC 178 >gi|50345279 claudin 18 isoform 2 [Homo sapiens] Length = 261 Score = 147 bits (371), Expect = 6e-36 Identities = 77/220 (35%), Positives = 119/220 (54%), Gaps = 14/220 (6%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA + Q LG+ ++L G GIIA+T + QW + + TAV Y+GLW SC +S+G Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPV-TAVFNYQGLWRSCVRESSG 59 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 +C+ Y +LL L +Q+ RALM+V ++LG + +++S+ +KC R+G AK + + Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPST-----------PVNARYEFGPALFVGW 169 G +FI++GLC + VS +A ++ F+ + V RY FG ALFVGW Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179 Query: 170 ASAGLAVLGGSFLCCTCP--EPERPNSSPQPYRPGPSAAA 207 + GL ++GG +C C PE N Y + A Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVA 219 >gi|47716519 claudin 20 [Homo sapiens] Length = 219 Score = 146 bits (368), Expect = 1e-35 Identities = 78/202 (38%), Positives = 113/202 (55%), Gaps = 5/202 (2%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60 MA++GLQLL + LAL G G++ +T LP WK + IITA+ GLWM C STG Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60 Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120 C L S+L+L H+Q+ARA MV+A +L + + S VGMKCTR+G K + Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE-TKSHASF 119 Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180 AGG F+ AG+ +L + WY + F + + P + ++E G A+++G+ SA L + G Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179 Query: 181 FLCCTC----PEPERPNSSPQP 198 C +C PE + QP Sbjct: 180 IFCTSCIKRNPEARLDPPTQQP 201 >gi|7705961 claudin 18 isoform 1 [Homo sapiens] Length = 261 Score = 144 bits (363), Expect = 5e-35 Identities = 75/221 (33%), Positives = 119/221 (53%), Gaps = 16/221 (7%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWK-QSSYAGDAIITAVGLYEGLWMSCASQST 59 M+ + Q++ + L++ G G IA+T + W Q Y D +T+V YEGLW SC QS+ Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY--DNPVTSVFQYEGLWRSCVRQSS 58 Query: 60 GQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVA 119 G +C+ Y ++L L +Q+ RALM+V ++LG + +++S+ +KC R+G AK + Sbjct: 59 GFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMT 118 Query: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPST-----------PVNARYEFGPALFVG 168 + G +FI++GLC + VS +A ++ F+ + V RY FG ALFVG Sbjct: 119 LTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVG 178 Query: 169 WASAGLAVLGGSFLCCTCP--EPERPNSSPQPYRPGPSAAA 207 W + GL ++GG +C C PE N Y + A Sbjct: 179 WVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVA 219 >gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] Length = 207 Score = 135 bits (341), Expect = 2e-32 Identities = 72/180 (40%), Positives = 106/180 (58%), Gaps = 22/180 (12%) Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63 S Q+ +GG+ ++A+T +WK ++ A ++ITA +Y+GLWM+CA Sbjct: 2 SRAQIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCA-------- 52 Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123 G+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A G Sbjct: 53 -----------GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAG 100 Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC 183 +FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG C Sbjct: 101 IVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFC 159 >gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 118 bits (295), Expect = 4e-27 Identities = 68/190 (35%), Positives = 102/190 (53%), Gaps = 4/190 (2%) Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63 + +Q +G L+L GW+ I +T LP WK + + + GLW +C Q +Q Sbjct: 7 TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63 Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123 CK +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182 L +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 Query: 183 CCTCPEPERP 192 C P Sbjct: 184 NCAACSSHAP 193 >gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 116 bits (291), Expect = 1e-26 Identities = 67/190 (35%), Positives = 101/190 (53%), Gaps = 4/190 (2%) Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63 + +Q +G L+ GW+ I +T LP WK + + + GLW +C Q +Q Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63 Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123 CK +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182 L +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 Query: 183 CCTCPEPERP 192 C P Sbjct: 184 NCAACSSHAP 193 >gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 116 bits (291), Expect = 1e-26 Identities = 67/190 (35%), Positives = 101/190 (53%), Gaps = 4/190 (2%) Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63 + +Q +G L+ GW+ I +T LP WK + + + GLW +C Q +Q Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63 Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123 CK +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182 L +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 Query: 183 CCTCPEPERP 192 C P Sbjct: 184 NCAACSSHAP 193 >gi|162417973 claudin 22 [Homo sapiens] Length = 220 Score = 114 bits (286), Expect = 5e-26 Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 4/190 (2%) Query: 7 QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKL 66 QL G L+L GWV + LP WK + + + GLW +C Q +QCK Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQCKD 66 Query: 67 YDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126 +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG L Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 Query: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFLCCT 185 +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L C Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 Query: 186 CPEPERPNSS 195 P +S Sbjct: 187 ACSSHAPLAS 196 >gi|10938016 claudin 11 [Homo sapiens] Length = 207 Score = 105 bits (261), Expect = 4e-23 Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 15/209 (7%) Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYE----GLWMSCAS 56 M + LQ++G+ + GW+G+I +T+ W + G I T L E GLW C Sbjct: 1 MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVT--CGYTIPTCRKLDELGSKGLWADCV- 57 Query: 57 QSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKG 116 +TG CK +L L G++Q+ RALM+ A +LG A++L + + C R+G +AK Sbjct: 58 MATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117 Query: 117 RVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176 R A G L IL LC L A W+ +E +T V+ FG +L+ GW A L + Sbjct: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRE----TTIVS----FGYSLYAGWIGAVLCL 169 Query: 177 LGGSFLCCTCPEPERPNSSPQPYRPGPSA 205 +GG + C + + + Y G S+ Sbjct: 170 VGGCVILCCAGDAQAFGENRFYYTAGSSS 198 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,363,073 Number of Sequences: 37866 Number of extensions: 367081 Number of successful extensions: 1577 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 51 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1476 Number of HSP's gapped (non-prelim): 78 length of query: 211 length of database: 18,247,518 effective HSP length: 98 effective length of query: 113 effective length of database: 14,536,650 effective search space: 1642641450 effective search space used: 1642641450 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.