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Search of human proteins with 183979973
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|183979973 claudin 19 isoform a [Homo sapiens]
(224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|183979973 claudin 19 isoform a [Homo sapiens] 452 e-127
gi|183979975 claudin 19 isoform b [Homo sapiens] 424 e-119
gi|10863887 claudin 1 [Homo sapiens] 259 1e-69
gi|153792186 claudin 7 [Homo sapiens] 245 2e-65
gi|11141861 claudin 9 [Homo sapiens] 192 1e-49
gi|4502875 claudin 3 [Homo sapiens] 192 1e-49
gi|4502877 claudin 4 [Homo sapiens] 189 2e-48
gi|195947374 claudin 5 [Homo sapiens] 187 6e-48
gi|195947372 claudin 5 [Homo sapiens] 187 6e-48
gi|225703142 claudin 14 [Homo sapiens] 186 1e-47
gi|21536294 claudin 14 [Homo sapiens] 186 1e-47
gi|225703138 claudin 14 [Homo sapiens] 186 1e-47
gi|6912314 claudin 14 [Homo sapiens] 186 1e-47
gi|225703140 claudin 14 [Homo sapiens] 186 1e-47
gi|153792768 claudin 6 [Homo sapiens] 186 2e-47
gi|9966781 claudin 2 [Homo sapiens] 171 6e-43
gi|6912316 claudin 17 [Homo sapiens] 164 4e-41
gi|40788011 claudin 8 [Homo sapiens] 161 5e-40
gi|7656981 claudin 15 [Homo sapiens] 161 5e-40
gi|5921465 claudin 10 isoform b [Homo sapiens] 160 1e-39
gi|33598916 claudin 10 isoform a [Homo sapiens] 152 2e-37
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 149 1e-36
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 146 1e-35
gi|47716519 claudin 20 [Homo sapiens] 146 2e-35
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 135 2e-32
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 118 5e-27
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 116 1e-26
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 116 1e-26
gi|162417973 claudin 22 [Homo sapiens] 114 5e-26
gi|10938016 claudin 11 [Homo sapiens] 105 4e-23
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 452 bits (1163), Expect = e-127
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAKGPLGV 224
FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAKGPLGV
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAKGPLGV 224
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 424 bits (1089), Expect = e-119
Identities = 210/211 (99%), Positives = 210/211 (99%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPV 211
FLCCTCPEPERPNSSPQPYRPGPSAAARE V
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 259 bits (662), Expect = 1e-69
Identities = 119/206 (57%), Positives = 155/206 (75%), Gaps = 1/206 (0%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MAN+GLQLLG+ LA GW+G I STALPQW+ SYAGD I+TA +YEGLWMSC SQSTG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Q+QCK++DSLL L +Q+ RALMVV +LLG +A+ ++ VGMKC + + + + K R+A+
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GGA+F+LAGL L A +WY + QEF++P TPVNARYEFG ALF GWA+A L +LGG+
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 181 FLCCTCPEPERPNSSPQPY-RPGPSA 205
LCC+CP +P+PY +P PS+
Sbjct: 181 LLCCSCPRKTTSYPTPRPYPKPAPSS 206
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 245 bits (626), Expect = 2e-65
Identities = 108/190 (56%), Positives = 145/190 (76%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MANSGLQLLG+ +AL GWVG++A TA+PQW+ SSYAGD IITA +Y+GLWM C +QSTG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
+ CK+YDS+LAL +Q+ RALMVV+++LGF+AM ++ +GMKCTR G + + K R+A+
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG +FI+AGL L A SWY + +F+NP P N +YEFGPA+F+GWA + L +LGG+
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 181 FLCCTCPEPE 190
L C+CP E
Sbjct: 181 LLSCSCPGNE 190
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 192 bits (489), Expect = 1e-49
Identities = 95/210 (45%), Positives = 138/210 (65%), Gaps = 4/210 (1%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++GL+LLG LA+ GW+G + S ALP WK +++ G++I+ A ++EGLWMSC QSTG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Q+QCK+YDSLLAL +Q+ARAL V+A+LL + +++++ G +CT + AK R+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEG-AKARIVL 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
G + +LAG+ L V W A + Q+F+NP + E G +L++GWA+A L +LGG
Sbjct: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
Query: 181 FLCCTCPEP--ERPNSSPQPYR-PGPSAAA 207
LCCTCP P ERP Y P S A+
Sbjct: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGAS 209
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 192 bits (489), Expect = 1e-49
Identities = 94/207 (45%), Positives = 136/207 (65%), Gaps = 6/207 (2%)
Query: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
GL++ G LA+ GW+G I ALP W+ S++ G IIT+ ++EGLWM+C QSTGQ+QC
Sbjct: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63
Query: 65 KLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGA 124
K+YDSLLAL +Q+ARAL+VVA+LL +++++VG +CT + AK ++ I G
Sbjct: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122
Query: 125 LFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCC 184
LF+LA L TL VSW A + ++F+NP P + E G L+VGWA+A L +LGG+ LCC
Sbjct: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182
Query: 185 TCPEPERPNSSPQ-----PYRPGPSAA 206
+CP E+ ++ + P GP A+
Sbjct: 183 SCPPREKKYTATKVVYSAPRSTGPGAS 209
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 189 bits (480), Expect = 2e-48
Identities = 91/207 (43%), Positives = 135/207 (65%), Gaps = 2/207 (0%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA+ GLQ++G LA+ GW+ ++ ALP W+ +++ G I+T+ ++EGLWM+C QSTG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Q+QCK+YDSLLAL +Q+ARAL+++++++ + ++LSVVG KCT + AK + I
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDES-AKAKTMI 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
G +F+LAGL + VSW A + Q+F+NP + E G +L+VGWA++GL +LGG
Sbjct: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAA 207
LCC CP P Y SAAA
Sbjct: 180 LLCCNCP-PRTDKPYSAKYSAARSAAA 205
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 187 bits (475), Expect = 6e-48
Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
+QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 181 FLCCTC------PEPERPNSSPQPYRP 201
LCC P+ P P RP
Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 187 bits (475), Expect = 6e-48
Identities = 91/207 (43%), Positives = 131/207 (63%), Gaps = 7/207 (3%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
M ++ L++LG L L GW G+I + LP W+ +++ I+TA ++GLWMSC QSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
+QCK+YDS+LAL +Q+ARAL V AVLL FVA+ +++ G +CT P AK RVA+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGP-AKARVAL 204
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG L++ GL L + W+A +V +EF++PS PV+ +YE G AL++GWA+ L ++GG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 181 FLCCTC------PEPERPNSSPQPYRP 201
LCC P+ P P RP
Sbjct: 265 LLCCGAWVCTGRPDLSFPVKYSAPRRP 291
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 186 bits (473), Expect = 1e-47
Identities = 98/221 (44%), Positives = 139/221 (62%), Gaps = 5/221 (2%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 FLCCTCPE--PERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
LC +C + P RP +P R + A P + PA+ K
Sbjct: 180 LLCLSCQDEAPYRPYQAPP--RATTTTANTAPAYQPPAAYK 218
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 186 bits (473), Expect = 1e-47
Identities = 98/221 (44%), Positives = 139/221 (62%), Gaps = 5/221 (2%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 FLCCTCPE--PERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
LC +C + P RP +P R + A P + PA+ K
Sbjct: 180 LLCLSCQDEAPYRPYQAPP--RATTTTANTAPAYQPPAAYK 218
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 186 bits (473), Expect = 1e-47
Identities = 98/221 (44%), Positives = 139/221 (62%), Gaps = 5/221 (2%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 FLCCTCPE--PERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
LC +C + P RP +P R + A P + PA+ K
Sbjct: 180 LLCLSCQDEAPYRPYQAPP--RATTTTANTAPAYQPPAAYK 218
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 186 bits (473), Expect = 1e-47
Identities = 98/221 (44%), Positives = 139/221 (62%), Gaps = 5/221 (2%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 FLCCTCPE--PERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
LC +C + P RP +P R + A P + PA+ K
Sbjct: 180 LLCLSCQDEAPYRPYQAPP--RATTTTANTAPAYQPPAAYK 218
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 186 bits (473), Expect = 1e-47
Identities = 98/221 (44%), Positives = 139/221 (62%), Gaps = 5/221 (2%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++ +QLLG+ L+ G VG + +T LP W+++++ G I+TAV +GLWM C STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QC++Y SLLAL +Q+ARALMV++ LL +A +V+GMKCTR P AK AI
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTP-AKTTFAI 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
GG LFILAGL + AVSW V Q F+NP P ++E G AL++G+ S+ L+++GG+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179
Query: 181 FLCCTCPE--PERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
LC +C + P RP +P R + A P + PA+ K
Sbjct: 180 LLCLSCQDEAPYRPYQAPP--RATTTTANTAPAYQPPAAYK 218
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 186 bits (471), Expect = 2e-47
Identities = 92/221 (41%), Positives = 140/221 (63%), Gaps = 10/221 (4%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++G+Q+LG L L GWV + S ALP WK +++ G++I+ A ++EGLWMSC QSTG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Q+QCK+YDSLLAL +Q+ARAL V+A+L+ +++ + G KCT + +K R+ +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
G +F+++G+ TL V W A + ++F+NP + E G +L++GWA++GL +LGG
Sbjct: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAKGP 221
LCCTC P + P Y S +A PA ++GP
Sbjct: 180 LLCCTC--PSGGSQGPSHYMARYSTSA-------PAISRGP 211
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 171 bits (432), Expect = 6e-43
Identities = 89/219 (40%), Positives = 129/219 (58%), Gaps = 1/219 (0%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA+ GLQL+GY L L G +G + + LP WK SSY G +I+TAVG +GLWM CA+ STG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
QC +Y +LL L IQ+A+A+MV + + +A ++SVVGM+CT V AK RVA+
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCT-VFCQESRAKDRVAV 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
AGG FIL GL V+W + ++F++P P + ++E G AL++G S+ +++ G
Sbjct: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179
Query: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAK 219
LC +C ++ Y+ P A P P K
Sbjct: 180 ILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVK 218
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 164 bits (416), Expect = 4e-41
Identities = 85/200 (42%), Positives = 120/200 (60%), Gaps = 2/200 (1%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA LQ+ G L G VG +A+T LPQW+ S++ G II L+EGLWM+C Q+
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
++QCK Y SLLAL +++ARALM VAV L +A+++ + GMK + SN AK +
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
G LFIL G+ L VSW A ++ ++F+NP+ + + E G ALF+GWASA + +GG
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180
Query: 181 FLC--CTCPEPERPNSSPQP 198
LC C C ++ P P
Sbjct: 181 LLCGFCCCNRKKQGYRYPVP 200
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 161 bits (407), Expect = 5e-40
Identities = 72/184 (39%), Positives = 114/184 (61%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA L++ G FL G VG +A T +PQW+ S++ + I+ +EGLWM+C Q+
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
++QCK+YDSLLAL +Q+AR LM A ++ F+A +++++GMKCTR N K + +
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
G +FI+ G+ L VSW A + ++F+N V + E G AL++GW +A + ++GG+
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 181 FLCC 184
CC
Sbjct: 181 LFCC 184
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 161 bits (407), Expect = 5e-40
Identities = 79/198 (39%), Positives = 127/198 (64%), Gaps = 5/198 (2%)
Query: 6 LQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCK 65
++ G+F+A G + + + W+ S+ G+ +IT ++E LW SCA+ S G C
Sbjct: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN-VITTNTIFENLWFSCATDSLGVYNCW 63
Query: 66 LYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGAL 125
+ S+LAL G+IQ+ RALM+ A+LLGF+ ++L + G++CT +G K ++A GAL
Sbjct: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
Query: 126 FILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC-- 183
ILAG+C + A+SWYA +T++FF+P P +YE GPAL++GW+++ +++LGG LC
Sbjct: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182
Query: 184 CTCPEPERPNSSP-QPYR 200
C C E P +S +PY+
Sbjct: 183 CCCGSDEDPAASARRPYQ 200
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 160 bits (404), Expect = 1e-39
Identities = 78/183 (42%), Positives = 116/183 (63%), Gaps = 3/183 (1%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++ +++ + +++ GWV + ++ WK S+ G I TA + LW +C + STG
Sbjct: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTAT-YWANLWKACVTDSTG 59
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
CK + S+LALDG+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A
Sbjct: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIAC 118
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
G +FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG
Sbjct: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177
Query: 181 FLC 183
C
Sbjct: 178 IFC 180
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 152 bits (384), Expect = 2e-37
Identities = 74/180 (41%), Positives = 114/180 (63%), Gaps = 3/180 (1%)
Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63
S Q+ +GG+ ++A+T +WK ++ A ++ITA +Y+GLWM+CA + G
Sbjct: 2 SRAQIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGNALGSFH 60
Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123
C+ + ++ + G+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A G
Sbjct: 61 CRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAG 119
Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC 183
+FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG C
Sbjct: 120 IVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFC 178
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 149 bits (377), Expect = 1e-36
Identities = 78/223 (34%), Positives = 121/223 (54%), Gaps = 14/223 (6%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA + Q LG+ ++L G GIIA+T + QW + + TAV Y+GLW SC +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPV-TAVFNYQGLWRSCVRESSG 59
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
+C+ Y +LL L +Q+ RALM+V ++LG + +++S+ +KC R+G AK + +
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPST-----------PVNARYEFGPALFVGW 169
G +FI++GLC + VS +A ++ F+ + V RY FG ALFVGW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 170 ASAGLAVLGGSFLCCTCP--EPERPNSSPQPYRPGPSAAAREP 210
+ GL ++GG +C C PE N Y + A +P
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKP 222
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 146 bits (369), Expect = 1e-35
Identities = 76/224 (33%), Positives = 121/224 (54%), Gaps = 16/224 (7%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWK-QSSYAGDAIITAVGLYEGLWMSCASQST 59
M+ + Q++ + L++ G G IA+T + W Q Y D +T+V YEGLW SC QS+
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY--DNPVTSVFQYEGLWRSCVRQSS 58
Query: 60 GQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
G +C+ Y ++L L +Q+ RALM+V ++LG + +++S+ +KC R+G AK +
Sbjct: 59 GFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMT 118
Query: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPST-----------PVNARYEFGPALFVG 168
+ G +FI++GLC + VS +A ++ F+ + V RY FG ALFVG
Sbjct: 119 LTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVG 178
Query: 169 WASAGLAVLGGSFLCCTCP--EPERPNSSPQPYRPGPSAAAREP 210
W + GL ++GG +C C PE N Y + A +P
Sbjct: 179 WVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKP 222
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 146 bits (368), Expect = 2e-35
Identities = 78/202 (38%), Positives = 113/202 (55%), Gaps = 5/202 (2%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
MA++GLQLL + LAL G G++ +T LP WK + IITA+ GLWM C STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
C L S+L+L H+Q+ARA MV+A +L + + S VGMKCTR+G K +
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE-TKSHASF 119
Query: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
AGG F+ AG+ +L + WY + F + + P + ++E G A+++G+ SA L + G
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
Query: 181 FLCCTC----PEPERPNSSPQP 198
C +C PE + QP
Sbjct: 180 IFCTSCIKRNPEARLDPPTQQP 201
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 135 bits (341), Expect = 2e-32
Identities = 72/180 (40%), Positives = 106/180 (58%), Gaps = 22/180 (12%)
Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63
S Q+ +GG+ ++A+T +WK ++ A ++ITA +Y+GLWM+CA
Sbjct: 2 SRAQIWALVSGVGGFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCA-------- 52
Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123
G+IQ+ R LM+ AV LGF + ++ GMKCT+VG S+ AK ++A G
Sbjct: 53 -----------GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAG 100
Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC 183
+FIL+GLC++T S YA +T EFF+P V +YE G ALF+GWA A L ++GG C
Sbjct: 101 IVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFC 159
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 118 bits (295), Expect = 5e-27
Identities = 68/190 (35%), Positives = 102/190 (53%), Gaps = 4/190 (2%)
Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63
+ +Q +G L+L GW+ I +T LP WK + + + GLW +C Q +Q
Sbjct: 7 TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63
Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123
CK +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182
L +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 183 CCTCPEPERP 192
C P
Sbjct: 184 NCAACSSHAP 193
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 116 bits (291), Expect = 1e-26
Identities = 67/190 (35%), Positives = 101/190 (53%), Gaps = 4/190 (2%)
Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63
+ +Q +G L+ GW+ I +T LP WK + + + GLW +C Q +Q
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63
Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123
CK +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182
L +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 183 CCTCPEPERP 192
C P
Sbjct: 184 NCAACSSHAP 193
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 116 bits (291), Expect = 1e-26
Identities = 67/190 (35%), Positives = 101/190 (53%), Gaps = 4/190 (2%)
Query: 4 SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63
+ +Q +G L+ GW+ I +T LP WK + + + GLW +C Q +Q
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63
Query: 64 CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123
CK +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182
L +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 183 CCTCPEPERP 192
C P
Sbjct: 184 NCAACSSHAP 193
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 114 bits (286), Expect = 5e-26
Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 4/190 (2%)
Query: 7 QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKL 66
QL G L+L GWV + LP WK + + + GLW +C Q +QCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQCKD 66
Query: 67 YDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126
+DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG L
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFLCCT 185
+G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L C
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
Query: 186 CPEPERPNSS 195
P +S
Sbjct: 187 ACSSHAPLAS 196
>gi|10938016 claudin 11 [Homo sapiens]
Length = 207
Score = 105 bits (261), Expect = 4e-23
Identities = 68/209 (32%), Positives = 104/209 (49%), Gaps = 15/209 (7%)
Query: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYE----GLWMSCAS 56
M + LQ++G+ + GW+G+I +T+ W + G I T L E GLW C
Sbjct: 1 MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVT--CGYTIPTCRKLDELGSKGLWADCV- 57
Query: 57 QSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKG 116
+TG CK +L L G++Q+ RALM+ A +LG A++L + + C R+G +AK
Sbjct: 58 MATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKY 117
Query: 117 RVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176
R A G L IL LC L A W+ +E +T V+ FG +L+ GW A L +
Sbjct: 118 RRAQLAGVLLILLALCALVATIWFPVCAHRE----TTIVS----FGYSLYAGWIGAVLCL 169
Query: 177 LGGSFLCCTCPEPERPNSSPQPYRPGPSA 205
+GG + C + + + Y G S+
Sbjct: 170 VGGCVILCCAGDAQAFGENRFYYTAGSSS 198
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,032,339
Number of Sequences: 37866
Number of extensions: 433954
Number of successful extensions: 2548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 2400
Number of HSP's gapped (non-prelim): 143
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.