Guide to the Human Genome
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Search of human proteins with 18379328

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18379328 WW domain-containing adapter with a coiled-coil
region isoform 1 [Homo sapiens]
         (647 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18379328 WW domain-containing adapter with a coiled-coil regi...  1294   0.0  
gi|18379332 WW domain-containing adapter with a coiled-coil regi...   667   0.0  
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             67   4e-11
gi|151301154 mucin 6, gastric [Homo sapiens]                           66   1e-10
gi|116284392 mucin 2 precursor [Homo sapiens]                          64   3e-10
gi|167736355 mucin 4 isoform a [Homo sapiens]                          61   3e-09
gi|91982772 mucin 17 [Homo sapiens]                                    61   4e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   1e-08
gi|161019170 mucin 5AC [Homo sapiens]                                  59   1e-08
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        59   1e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    59   2e-08
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       58   3e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        56   9e-08
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    56   1e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    56   1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   2e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         55   3e-07
gi|83367077 mucin 16 [Homo sapiens]                                    54   3e-07
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    54   3e-07
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    54   3e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    54   4e-07
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                53   8e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   53   8e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   53   8e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   53   8e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    53   8e-07
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    53   8e-07
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    53   8e-07
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                53   8e-07
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                53   8e-07

>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score = 1294 bits (3349), Expect = 0.0
 Identities = 647/647 (100%), Positives = 647/647 (100%)

Query: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60
           MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
Sbjct: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60

Query: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120
           RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
Sbjct: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120

Query: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180
           PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
Sbjct: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180

Query: 181 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH 240
           FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH
Sbjct: 181 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH 240

Query: 241 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA
Sbjct: 241 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP 360
           QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP
Sbjct: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDP 360

Query: 361 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI 420
           NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI
Sbjct: 361 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI 420

Query: 421 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV 480
           SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV
Sbjct: 421 SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV 480

Query: 481 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA 540
           STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA
Sbjct: 481 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA 540

Query: 541 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE 600
           TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE
Sbjct: 541 TVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSE 600

Query: 601 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV 647
           ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
Sbjct: 601 ICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV 647


>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score =  667 bits (1720), Expect = 0.0
 Identities = 369/519 (71%), Positives = 393/519 (75%), Gaps = 43/519 (8%)

Query: 172 EANKMAVNSFPKDRDYRREVMQATATSGFASGM-------EDKHSSDASSLLPQNILSQT 224
           +A K +  S P   D+R E M+        + M       E+K+S        +N+ +  
Sbjct: 26  QALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHR 85

Query: 225 SRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPK-----KS 279
            R  D        E   + + +        +P+  PS    +P+    D         K 
Sbjct: 86  VRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKK 145

Query: 280 FDANGASTLSKLPTP-----------------TSSVPAQKTERKE--------------S 308
           +  N  + +S+   P                  +S P  +  R+E              S
Sbjct: 146 YYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGKS 205

Query: 309 TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 368
           TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP
Sbjct: 206 TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 265

Query: 369 ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST 428
           ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST
Sbjct: 266 ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST 325

Query: 429 QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 488
           QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG
Sbjct: 326 QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 385

Query: 489 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
           PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS
Sbjct: 386 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 445

Query: 549 ARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNL 608
           ARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNL
Sbjct: 446 ARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNL 505

Query: 609 RSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV 647
           RSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
Sbjct: 506 RSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV 544



 Score =  440 bits (1131), Expect = e-123
 Identities = 252/449 (56%), Positives = 290/449 (64%), Gaps = 15/449 (3%)

Query: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60
           MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR
Sbjct: 1   MVMYARKQQRLSDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLR 60

Query: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120
           RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN
Sbjct: 61  RSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNN 120

Query: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180
           PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS
Sbjct: 121 PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNS 180

Query: 181 FPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETH 240
           FPKDRDYRREVMQATATSGFASG         S        S  S  N        A   
Sbjct: 181 FPKDRDYRREVMQATATSGFASGKSTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAV 240

Query: 241 SSSTPVQHPIKPVVH-PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVP 299
             S   Q PI P++  P      +P+   TLQ ++        N   T +      +   
Sbjct: 241 PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAA-----VTQAS 295

Query: 300 AQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPV---SPVPQSPIPPL 356
            Q    K  T+G    +    T   S A+ L+ T A P++ S + +   +  P+S + P 
Sbjct: 296 LQSIIHKFLTAGPSAFN---ITSLISQAAQLS-TQAQPSNQSPMSLTSDASSPRSYVSPR 351

Query: 357 LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNI 416
           +  P      +  L +T  +++     + +  V    V+Q++ Q  +      G    + 
Sbjct: 352 ISTPQTNTVPIKPLISTPPVSSQPKVSTPV--VKQGPVSQSATQQPVTADKQQGHEPVSP 409

Query: 417 TSLISQAAQLSTQAQPSNQSPMSLTSDAS 445
            SL   ++Q S    P++ S  S  S+A+
Sbjct: 410 RSLQRSSSQRSPSPGPNHTSNSSNASNAT 438


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 72/300 (24%), Positives = 129/300 (43%), Gaps = 22/300 (7%)

Query: 277  KKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP 336
            KK+ +  G S  SKLP   +   A   ++ +S++   P++ +   PSTS++   + ++  
Sbjct: 1711 KKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPL 1770

Query: 337  PTSASAVPVS---PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAA 393
            P + + VP S   PVP S + P+L   +     +PA        +++V  S       AA
Sbjct: 1771 PATLTPVPASTSAPVPASTLAPVLASTS---APVPASPLAPVSASASVSASVPASTSAAA 1827

Query: 394  VTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP 453
            +T +S  +       + P+   I + +S  A ++  A  S   P+  ++ AS+     +P
Sbjct: 1828 ITSSSAPA-------SAPAPTPILASVSTPASVTILASAS--IPILASALASTSAPTPAP 1878

Query: 454  RISTPQTNTVPIKPLISTPPVSSQP----KVSTPVVKQGPVSQSATQQPVTADKQ-QGHE 508
              S+P    +    + ++ P +S P      S P     PVS      P  A  Q Q H+
Sbjct: 1879 AASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHK 1938

Query: 509  PVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLI 568
            PV  ++  +++SQ S  P P+    S+   N T    +  +  T      L A   +N +
Sbjct: 1939 PV--QNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKV 1996


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 81/365 (22%), Positives = 134/365 (36%), Gaps = 31/365 (8%)

Query: 202  SGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPS 261
            SG    HSS +++  P ++ S TS  +  +       T + +        PV H  +  S
Sbjct: 1507 SGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566

Query: 262  TVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTT 321
            + P  PFT  S       F + G  T +   T T++ P     +    +   P S S  T
Sbjct: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTPSHPQTTLPTHVPPFSTSLVT 1625

Query: 322  PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ-------DPNLLRQLLPALQATL 374
            PST +   + PT A   +++++   P    P P  L+        P +        QA  
Sbjct: 1626 PSTHTV--ITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALS 1683

Query: 375  QLNNSNVDISKINEVLT---AAVTQASLQSIIHKFLTAGPSAFNIT-----------SLI 420
             LN +    S  +   +   A  T  S  +I     + G     +T           S  
Sbjct: 1684 SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTA 1743

Query: 421  SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV-PIKPLISTP-PVSSQP 478
              +  L +    ++   ++ TS  S   ++ S    TP  +T       + TP    S P
Sbjct: 1744 KTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPP 1803

Query: 479  KVSTPVVKQGPVSQSATQQPVT-ADKQQGHEPVSPRSLQRSSSQRSPSPG----PNHTSN 533
              +TP+   GPV+ ++ Q   T       H  +       S+S  +PS      P HT  
Sbjct: 1804 TGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQM 1863

Query: 534  SSNAS 538
            +++AS
Sbjct: 1864 ATSAS 1868



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 97/386 (25%), Positives = 142/386 (36%), Gaps = 50/386 (12%)

Query: 197  TSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRA-ETHS---SSTPVQH--PI 250
            TS   + +   H+S  +     +  S TS       RLP    THS    +TP+    P+
Sbjct: 1762 TSTSTTSITPNHTSTGTRTPVAHTTSATSS------RLPTPFTTHSPPTGTTPISSTGPV 1815

Query: 251  KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTS 310
                  T T    PS P T    H P  S         + L TP++      T  + +TS
Sbjct: 1816 TATSFQTTTTYPTPSHPHTTLPTHVPSFS---------TSLVTPSTHTVIIPTHTQMATS 1866

Query: 311  GDKPVSHSCTT-----PSTSSASGLNPTSAPPT-SASAVPVSPVPQSPIPPLLQDP-NLL 363
                  HS  T     P+T  A+G   T+ P T + S    SP   S        P +  
Sbjct: 1867 AS---IHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTS 1923

Query: 364  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGP----SAFNITSL 419
                P +  T   N +    S       A  T AS   +   F T  P    S F+ T  
Sbjct: 1924 STHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGP 1983

Query: 420  ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 479
            ++  +  +T   P+   P +       P    S  + TP T+TV I     T   +S   
Sbjct: 1984 MTATSFQTTTTYPTPSHPQTTLPTHVPP---FSTSLVTPSTHTVIITT--HTQMATSASI 2038

Query: 480  VSTPVVKQGPVSQSATQQPVTADKQQGHEPVSP-RSLQRSSSQRSPSPGPNHTSNSSNAS 538
             STP         + T  P T  K  G    +P  ++  S + ++ S     T++SS  S
Sbjct: 2039 HSTP---------TGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFIS 2089

Query: 539  NATVVPQNSSARSTCSLTPALAAHFS 564
            +++ +PQNSS+R   S       H S
Sbjct: 2090 SSSWLPQNSSSRPPSSPITTQLPHLS 2115



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 81/341 (23%), Positives = 122/341 (35%), Gaps = 53/341 (15%)

Query: 237  AETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS 296
            +  H+ ++P Q P+         P+T+ SS  T  S   P+         T +  P  TS
Sbjct: 1241 SSNHTPASPTQTPL--------LPATLTSSKPTASSGEPPR--------PTTAVTPQATS 1284

Query: 297  SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP-QSPIPP 355
             +P   T R  +T   KP     TT +T+S +    TS   ++       P P  S   P
Sbjct: 1285 GLPPTATLRSTAT---KPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSP 1341

Query: 356  LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
             L  P    Q LP   AT          S      T   T            T       
Sbjct: 1342 TL--PKSTNQELPGTTATQTTGPRPTPAS------TTGPTTPQPGQPTRPTATETTQTRT 1393

Query: 416  ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS---PRISTPQTNTVPIKPLISTP 472
             T   +     +T + P+  SP+  T   ++   + +   P  S P+T      P  ST 
Sbjct: 1394 TTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTS 1453

Query: 473  PVS-SQPKVSTPVVKQGPVSQS------ATQQPVTADKQQGH----EPVSPRSLQRS--- 518
             V+ S   V TP   Q   S S       T  P T  K  G      P++P +   S   
Sbjct: 1454 LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH 1513

Query: 519  ---SSQRSPSPGPNHTSNSSN-----ASNATVVPQNSSARS 551
               S+ ++P+   +HTS++ +      S  T+ P  +S R+
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRT 1554



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 83/354 (23%), Positives = 133/354 (37%), Gaps = 55/354 (15%)

Query: 237  AETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS 296
            A  HS  T    P   +    +T +  P +P T  +   P  SF    A T + LP  TS
Sbjct: 1867 ASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPS-SFST--AKTSTSLPYHTS 1923

Query: 297  SVPAQK---------TERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSP 347
            S    +         T +  ST    PV+H+ T+ S+S       T +PPT +S      
Sbjct: 1924 STHHPEVTPTSTTNITPKHTSTGTRTPVAHT-TSASSSRLPTPFTTHSPPTGSS------ 1976

Query: 348  VPQSPIPPLLQDPNLLRQLLPAL---QATLQLN----NSNVDISKINEVLTAAVTQASLQ 400
             P S   P+           P     Q TL  +    ++++     + V+    TQ +  
Sbjct: 1977 -PFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATS 2035

Query: 401  SIIHKFLTAG---PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST 457
            + IH   T     P+    T     A  ++     ++Q+  S  S A++  S++S     
Sbjct: 2036 ASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSF-STATASSSFISSSSWL 2094

Query: 458  PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR---- 513
            PQ ++       S PP       S+P+  Q P   SAT    T ++       SP     
Sbjct: 2095 PQNSS-------SRPP-------SSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPST 2140

Query: 514  ------SLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAA 561
                  S   S    SPS G + +  S+   + T+   + S+ ST   T +++A
Sbjct: 2141 VSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA 2194



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 65/275 (23%), Positives = 105/275 (38%), Gaps = 34/275 (12%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV 315
            P  + S  PSSP T Q  H    +   +  + LS   +P+ S P+  +    S+      
Sbjct: 2095 PQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT 2154

Query: 316  S---------------HSCTTPSTSSAS-GLNPTSAPPTSASAVPVSPVPQSPI----PP 355
            S               HS T  S S +S   +PT+A  +++   P SP   + I    P 
Sbjct: 2155 SSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPH 2214

Query: 356  LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
             +  P  L  LLP    T+    S+   S      +   T AS         T    AF+
Sbjct: 2215 TISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTAS---------THTAPAFS 2265

Query: 416  ITSLISQAAQLSTQAQPSNQSPMS--LTSDASSPRSYVSPRISTPQTNTVPIKPLISTPP 473
              S  S++  L+T+   S    ++  +T   +SP + ++ R   P T +   + L S+  
Sbjct: 2266 SQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGP-TLSPTTRFLTSSLT 2324

Query: 474  VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 508
                   S PV   G  + + T   V + ++Q  E
Sbjct: 2325 AHGSTPASAPVSSLG--TPTPTSPGVCSVREQQEE 2357



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 83/356 (23%), Positives = 125/356 (35%), Gaps = 50/356 (14%)

Query: 224  TSRHNDRDYRLPRAE--THSSST-----PVQHPIKPVVHPTATPSTVPSSPFTLQSDHQP 276
            T      +Y  P+    THS  T     P   P+        T    PS P T    H P
Sbjct: 1389 TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVP 1448

Query: 277  KKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSC-TTPSTSSASGLNPTSA 335
              S      ST + + TPT +  A       + +G  P   +   T ST +A  + PT++
Sbjct: 1449 PFSTSLVTPSTHTVI-TPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTS 1507

Query: 336  PPTSA-SAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAV 394
              + A S+   +  P S                      L  + S+    ++    T  +
Sbjct: 1508 GTSQAHSSFSTNKTPTS----------------------LHSHTSSTHHPEVTPTSTTTI 1545

Query: 395  TQASLQSIIHKFLTAGPSAFNITSLISQ-AAQLSTQAQPSNQSPMSLT---SDASSPRSY 450
            T     +      T  P A   ++  S+     +T + P+  SP S T   +  S   + 
Sbjct: 1546 TPNPTST-----RTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTT 1600

Query: 451  VSPRISTPQTNTVPIKPLISTPPVS-SQPKVSTPVVKQGPVSQS------ATQQPVTADK 503
              P  S PQT      P  ST  V+ S   V TP   Q   S S       T  P T  K
Sbjct: 1601 TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLK 1660

Query: 504  QQGHEPVSPRSLQRSS--SQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              G    +P     +S  SQ   S     TS S ++  ++     +++ ST ++TP
Sbjct: 1661 ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP 1716


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 72/331 (21%), Positives = 116/331 (35%), Gaps = 29/331 (8%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P   T ++  P   P  P+   T  P T   SP  + +   P  +   +  +T    PT 
Sbjct: 1424 PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP-PISTTTTPPPTTTPSPPTTTPSPPTT 1482

Query: 295  TSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 354
            T S P   T     T+   P +   TTP T  AS    T+ PPT+  + P +     P P
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPT---TTPITPPAS---TTTLPPTTTPSPPTTTTTTPP-P 1535

Query: 355  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 414
                 P     + P    T     +               T  S  +      T  PS  
Sbjct: 1536 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT------TTTPSPP 1589

Query: 415  NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST----PQTNTVPIKPLIS 470
             IT+         +    +  +P   T+ +    + ++P  ST    P T   P     +
Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649

Query: 471  TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 530
            TPP ++ P   T      P++ + T  P T        P++      +++  +PSP    
Sbjct: 1650 TPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS----SPITTTPSPPTTTMTTPSP---- 1701

Query: 531  TSNSSNASNATVVPQNSSARS---TCSLTPA 558
            T+  S+    T  P +++  S   T   TP+
Sbjct: 1702 TTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 72/320 (22%), Positives = 114/320 (35%), Gaps = 30/320 (9%)

Query: 243  STPVQHPIKPVVHPTAT----PSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV 298
            +TP      P   PT+T    P+T PS P T  +   P  +      +T +  PT T S 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 299  PAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ 358
            P   T     T+   P +   TTPS  + +   PT+   T       SP   +PI P   
Sbjct: 1457 PISTTTTPPPTTTPSPPT---TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513

Query: 359  DPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITS 418
               L     P+   T     +    +  +   T  +T  +  + +    T  P     T+
Sbjct: 1514 TTTLPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571

Query: 419  LISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP 478
                    +T + P+  +P   T   ++P    +P   T  T T P       P  +  P
Sbjct: 1572 ----PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP-------PTTTPSP 1620

Query: 479  KVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNAS 538
              +TP+    P + + T  P T           P +        +PSP P  T+ S   +
Sbjct: 1621 PTTTPIT---PPTSTTTLPPTTTPSP------PPTTTTTPPPTTTPSP-PTTTTPSPPIT 1670

Query: 539  NATVVPQNSSARSTCSLTPA 558
              T  P  ++  S  + TP+
Sbjct: 1671 TTTTPPPTTTPSSPITTTPS 1690



 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 72/339 (21%), Positives = 114/339 (33%), Gaps = 74/339 (21%)

Query: 239  THSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV 298
            T + S P   PI P    T  P T   SP T  +   P  +  +   +T    PT T+++
Sbjct: 1497 TTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1556

Query: 299  PAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ 358
            P        +T    P + +   P+T+ +     T +PPT  +  P  P   +P PP   
Sbjct: 1557 P------PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP--PPTTTPSPP--- 1605

Query: 359  DPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITS 418
                                            T   T            T  PS    T 
Sbjct: 1606 -------------------------------TTTTTTPPP---------TTTPSPPTTTP 1625

Query: 419  LISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL--ISTPPVSS 476
            +       ST   P   +P    +  ++P    +P   +P T T P  P+   +TPP ++
Sbjct: 1626 I---TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSPPITTTTTPPPTT 1679

Query: 477  QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP------SPGPNH 530
             P          P +   T  P T        P++  +   S++  SP      +P P  
Sbjct: 1680 TPSSPITTTPSPPTTTMTTPSPTTTPS----SPITTTTTPSSTTTPSPPPTTMTTPSPTT 1735

Query: 531  TSNSSNASNATVVPQNSSARSTC-----SLTPALAAHFS 564
            T +    +  T+ P  +S+  T      S+TP   + FS
Sbjct: 1736 TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 60/268 (22%), Positives = 98/268 (36%), Gaps = 19/268 (7%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P   T ++  P   P  P   P   P++  + P T      P  +      +T S   T 
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584

Query: 295  TSSVPAQKTERKESTSGDKPVSHSCTT--PSTSSASGLNPTSAPPTSASAVPVSPVPQ-- 350
            T S P   T     T+   P + + TT  P+T+ +        PPTS + +P +  P   
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644

Query: 351  -----SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHK 405
                 +P P     P       P +  T     +    S I    +   T  +  S    
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS---- 1700

Query: 406  FLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS---PRISTPQTNT 462
              T  PS+  IT+  + ++  +    P+  +  S T+  S P + ++   P  ++    T
Sbjct: 1701 -PTTTPSS-PITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758

Query: 463  VPIKPLISTPPVSSQPKVSTPVVKQGPV 490
             P+ P I TPP  S    +TP     P+
Sbjct: 1759 TPLPPSI-TPPTFSPFSTTTPTTPCVPL 1785



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 73/335 (21%), Positives = 122/335 (36%), Gaps = 32/335 (9%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 3993 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4051

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 4052 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 4103

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 4104 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 4160

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
            + P  +  P  +Q   +TP+      + + T  P     Q G  P +  S    +   + 
Sbjct: 4161 VTP--TPTPTGTQTPTTTPIT----TTTTVTPTPTPTGTQTG--PPTHTSTAPIAELTTS 4212

Query: 525  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTPAL 559
            +P P   S++   S +T  P   S     +L PA+
Sbjct: 4213 NPPPE--SSTPQTSRSTSSPLTESTTLLSTLPPAI 4245



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 67/328 (20%), Positives = 120/328 (36%), Gaps = 47/328 (14%)

Query: 239  THSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV 298
            T  ++T  ++P  P   P  T +TV  +P    +  Q   +      +T++  PTPT + 
Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGT- 1939

Query: 299  PAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPVPQSPIPPLL 357
                      T    P++ + T   T + +G   PT+ P T+ + V  +P P     P  
Sbjct: 1940 ---------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1990

Query: 358  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT 417
                    + P    T     +   I+    V T   T    Q+         P+   IT
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPIT 2040

Query: 418  SLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPP 473
            +  +       T  Q    +P++ T+  +   +P    +P  +TP T T  + P  +  P
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTP 2097

Query: 474  VSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPN 529
              +Q   +TP+     V    + + TQ P T        P++      +++  +P+P P 
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPT 2144

Query: 530  HTSNSSNASNATVVPQNSSARSTCSLTP 557
             T   +     T      +   T + TP
Sbjct: 2145 GTQTPTTTPITTTTTVTPTPTPTGTQTP 2172



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 78/373 (20%), Positives = 128/373 (34%), Gaps = 68/373 (18%)

Query: 234  LPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLS---- 289
            LP   T S          P   P+   +T PS P T  +   P  +  +   +T S    
Sbjct: 1635 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTT 1694

Query: 290  ----KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPS---TSSASGLNPTSAPPTSASA 342
                  PT T S P   T    ST+   P   + TTPS   T S      T+ PPT+ S 
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS- 1753

Query: 343  VPVSPVPQSPIPPLLQDPNL--------LRQLLPALQATLQLNNSNVDISK-------IN 387
               SP+  +P+PP +  P              +P    T  L++   +  K       I 
Sbjct: 1754 ---SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIG 1810

Query: 388  EVLTAA-VTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ-PSNQSPMSL----- 440
            +V         S ++ ++  +  G     +   +S       + Q P    PM+      
Sbjct: 1811 DVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYE 1870

Query: 441  ------------TSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 488
                        T+  ++     +P  +TP T T  + P  +  P  +Q   +TP+    
Sbjct: 1871 INVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTT 1928

Query: 489  PV----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP 544
             V    + + TQ P T        P++      +++  +P+P P  T   +     T   
Sbjct: 1929 TVTPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPTTTPITTTTT 1975

Query: 545  QNSSARSTCSLTP 557
               +   T + TP
Sbjct: 1976 VTPTPTPTGTQTP 1988



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 2130 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 2240

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 2241 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2297

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 2298 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 2342

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2379



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 2337 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 2447

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 2448 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2504

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 2505 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 2549

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 2550 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2543

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 2544 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 2654

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 2655 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2711

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 2712 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 2756

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2793



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 2751 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 2861

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 2862 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2918

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 2919 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 2963

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 2964 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2957

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 2958 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 3068

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 3069 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3125

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 3126 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 3170

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3164

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 3165 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 3275

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 3276 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3332

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 3333 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 3377

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 3378 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3414



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 3372 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 3482

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 3483 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3539

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 3540 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 3584

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 3585 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 3579 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 3689

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 3690 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3746

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 3747 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 3791

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3828



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 41/337 (12%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPS---TVPSSPFTLQSDHQPKKSFDANGASTLS 289
            P      + TP   PI     V PT TP+   T  ++P T  +   P  +       T +
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLN-PTSAPPTSASAVPVSPV 348
             + T T+  P   T     T    P++ + T   T + +G   PT+ P T+ + V  +P 
Sbjct: 3786 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
            P     P          + P    T     +   I+    V T   T    Q+       
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQT------- 3896

Query: 409  AGPSAFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDAS---SPRSYVSPRISTPQTNTVP 464
              P+   IT+  +       T  Q    +P++ T+  +   +P    +P  +TP T T  
Sbjct: 3897 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3953

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPV----SQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            + P  +  P  +Q   +TP+     V    + + TQ P T        P++      +++
Sbjct: 3954 VTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-------PIT------TTT 3998

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
              +P+P P  T   +     T      +   T + TP
Sbjct: 3999 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4035



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 12/120 (10%)

Query: 217  PQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTAT-PSTVPSSPFTLQSDH- 274
            P++   QTSR              + ST +   + P +  T+T P + P++P T    H 
Sbjct: 4216 PESSTPQTSRSTSSPL--------TESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHT 4267

Query: 275  -QPKKSFDANGASTLSK-LPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNP 332
              P  S   +   T ++   T +SS P   T +  +TS   P     +TPS    +GL P
Sbjct: 4268 LSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP 4327



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 23/136 (16%)

Query: 239  THSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP---T 295
            TH+S+ P+          T+ P    S+P T +S   P         + LS LP     T
Sbjct: 4199 THTSTAPIAELT------TSNPPPESSTPQTSRSTSSPL----TESTTLLSTLPPAIEMT 4248

Query: 296  SSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQS---- 351
            S+ P        +TSG   +S     PST+++    PT    T +S+ P     Q+    
Sbjct: 4249 STAPPSTPTAPTTTSGGHTLS---PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 4305

Query: 352  ---PIPPLLQDPNLLR 364
               P P  L  P+++R
Sbjct: 4306 AWTPTPTPLSTPSIIR 4321



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 37/131 (28%), Positives = 50/131 (38%), Gaps = 25/131 (19%)

Query: 235  PRAETHSSSTPVQHPIKPV--VHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP 292
            P      + TP   PI     V PT TP+   + P        P  +  A  A   +  P
Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP--------PTHTSTAPIAELTTSNP 4214

Query: 293  TPTSSVPAQKTERKESTSGDKPVSHSCTTPST--------SSASGLNPTSAPPTSASAVP 344
             P SS P      + S S   P++ S T  ST        S+A    PT AP T++    
Sbjct: 4215 PPESSTP------QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT-APTTTSGGHT 4267

Query: 345  VSPVPQSPIPP 355
            +SP P +   P
Sbjct: 4268 LSPPPSTTTSP 4278



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 50/251 (19%), Positives = 91/251 (36%), Gaps = 34/251 (13%)

Query: 315  VSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATL 374
            V+   T  +T++ +   PT+ P T+ + V  +P P     P          + P    T 
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1938

Query: 375  QLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS-QAAQLSTQAQPS 433
                +   I+    V T   T    Q+         P+   IT+  +       T  Q  
Sbjct: 1939 TQTPTTTPITTTTTV-TPTPTPTGTQT---------PTTTPITTTTTVTPTPTPTGTQTP 1988

Query: 434  NQSPMSLTSDAS---SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPV 490
              +P++ T+  +   +P    +P  +TP T T  + P  +  P  +Q   +TP+     V
Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTV 2045

Query: 491  ----SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 546
                + + TQ P T        P++      +++  +P+P P  T   +     T     
Sbjct: 2046 TPTPTPTGTQTPTTT-------PIT------TTTTVTPTPTPTGTQTPTTTPITTTTTVT 2092

Query: 547  SSARSTCSLTP 557
             +   T + TP
Sbjct: 2093 PTPTPTGTQTP 2103


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 102/417 (24%), Positives = 154/417 (36%), Gaps = 38/417 (9%)

Query: 194  ATATSGFASGMEDKHSSDASS--LLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
            ++A++G A+ +   ++S  S+   +P  + S +S        LP   T S+ST       
Sbjct: 3255 SSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTG------ 3308

Query: 252  PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
               H T  P T  SS  T  +   P    D + AST    P P +S  +  T        
Sbjct: 3309 ---HATPVPVTSTSSASTGHTTPLPVT--DTSSASTGDTTPLPVTSPSSASTGHTTPLHV 3363

Query: 312  DKPVSHSCTTPST------SSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 365
              P S S    ST      SSAS  + T  P T  S+V        P+  L         
Sbjct: 3364 TIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTT 3423

Query: 366  LLPALQATLQLNN--SNVDISKINEVLTA-----AVTQASLQSIIHKFL-----TAGPSA 413
             LP   A+       + + ++ ++ V T       VT AS  S  H        T+  S 
Sbjct: 3424 PLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAST 3483

Query: 414  FNITSL-ISQAAQLST-QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIST 471
             + T L ++  +  ST QA P   + +S  S   +    V+   S    +  P+ P+  T
Sbjct: 3484 GDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPL-PVTDT 3542

Query: 472  PPVSSQPKVSTPVVKQGPVSQS-ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 530
               S+      PV      S   AT  PVT          +P  +  +SS  +    P H
Sbjct: 3543 SSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLH 3602

Query: 531  TSNSSNASNATVVP---QNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQAS 584
             ++ S+AS   V P    ++S+ ST   TP L    S     H    P   A   ++
Sbjct: 3603 VTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSAST 3659



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 95/405 (23%), Positives = 168/405 (41%), Gaps = 52/405 (12%)

Query: 194  ATATSGFASGMEDKHSSDASS--LLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPI- 250
            ++++SG  + +    +S  S+  + P ++ S +S        LP   T S+ST    P+ 
Sbjct: 3575 SSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLL 3634

Query: 251  ----KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV-------- 298
                  V    ATP  V  +      D  P    D + AST    P P +S+        
Sbjct: 3635 VTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT 3694

Query: 299  -PAQKTERKESTSGDK-----PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQ-- 350
             P   T+   +++G        +  S +T  T      +P+SA    A+ +PV+ +    
Sbjct: 3695 TPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSAS 3754

Query: 351  ----SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK--INEVLTAAVTQASLQSIIH 404
                +P+P         R   P L  T   + S  D ++  + +V +A+   A+   +  
Sbjct: 3755 TGDTTPLPVTDTSSASTRHATP-LPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTS 3813

Query: 405  KFLTAGPSAFNITSL-ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV 463
               T+  S  + T L ++  + +ST     + + + +TS +S+   + +P    P T+T 
Sbjct: 3814 ---TSSASTGDTTPLPVTDTSSVST----GHATSLPVTSRSSASTGHATP---LPVTDTS 3863

Query: 464  PIKPLISTP-PVSSQPKVS----TPVVKQGPVSQS---ATQQPVTADKQQGHEPVSPRSL 515
             +    +TP PV+S   VS    TP+    P S S   AT  PVT+         +P  +
Sbjct: 3864 SVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPV 3923

Query: 516  QRSSSQRSPSPGPNHTSNSSNAS---NATVVPQNSSARSTCSLTP 557
              +SS  +    P H ++ S+AS    +T+   ++S+ ST   TP
Sbjct: 3924 TNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATP 3968



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 98/395 (24%), Positives = 147/395 (37%), Gaps = 48/395 (12%)

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTA------TPST 262
            S+    + P ++ S +S        LP     S+ST    P+ PV  P++      TP  
Sbjct: 1288 SASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL-PVTSPSSASTGDTTPLP 1346

Query: 263  VPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSC--T 320
            V  +         P    DA+ AST    P P +S+ +  T          P S S    
Sbjct: 1347 VTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 1406

Query: 321  TP----STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL------ 370
            TP     TSSAS  + T  P T AS+V        P+             LP        
Sbjct: 1407 TPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSAS 1466

Query: 371  --QAT--LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQL 426
              QAT  L  + S+V       +   + + AS   +    +T+  SA    +       L
Sbjct: 1467 TGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSL 1526

Query: 427  STQAQPSNQSPMSLTSDASSPRSYVSP-------RISTPQTNTVPIK-----------PL 468
            S+ A   +  P+ +TS +S+     +P        +ST  T  +P+            PL
Sbjct: 1527 SS-ASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPL 1585

Query: 469  ISTPPVSSQPKVSTPVVKQGPVSQSA---TQQPVTADKQQGHEPVSPRSLQRSSSQRSPS 525
              T   S+    +TP+    P S S    T  PVT          +P  +  +SS  +  
Sbjct: 1586 PVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGH 1645

Query: 526  PGPNHTSNSSNAS--NATVVPQNS-SARSTCSLTP 557
              P H ++ S+AS  +AT +P  S S+ ST   TP
Sbjct: 1646 ATPLHVTSPSSASTGHATPLPVTSTSSASTGHATP 1680



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 105/416 (25%), Positives = 163/416 (39%), Gaps = 58/416 (13%)

Query: 194  ATATSGFASGMEDKHSSDASSL-----LPQNILSQTSRHNDRDYRLPRAETHSSSTPVQH 248
            ++A++G A+ +   H +DASS+      P  + S +S  +     LP  +  S+ST    
Sbjct: 2343 SSASTGHATPL---HVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTT 2399

Query: 249  PIKPVV--------HPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
            P+ PV         H T  P T  SS  T  +   P  +   + AST    P P +S  +
Sbjct: 2400 PL-PVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTN--VSSASTGHATPLPVTSTSS 2456

Query: 301  QKTERKESTSGD--KPVSHSCTTP----STSSASGLNPTSAP---PTSASAVPVSPVPQS 351
              T       G     VS   TTP      SS S  + T  P   P+SAS    +P+P +
Sbjct: 2457 ASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVT 2516

Query: 352  PIP----------PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQA---- 397
              P          P+    +L  +   +L  T   + S    + +    T+A +      
Sbjct: 2517 DTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATP 2576

Query: 398  ----SLQSIIHKFLTAGPSAFNITSLISQAAQL------STQAQPSNQSPMSLTSDASSP 447
                S  S      T  P     ++   QA  L      S     +   P++ TS AS+ 
Sbjct: 2577 LPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTG 2636

Query: 448  RSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS---ATQQPVT--AD 502
             +   P  +T   +T    PL  T P S+    +TP+      S S   AT  PVT  + 
Sbjct: 2637 HATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASS 2696

Query: 503  KQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP-QNSSARSTCSLTP 557
               GH    P ++  S+S    +P P   ++S +  +AT +P  ++S+ ST   TP
Sbjct: 2697 VFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATP 2752



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 101/387 (26%), Positives = 144/387 (37%), Gaps = 56/387 (14%)

Query: 198  SGFASGMEDKHSSDASS--LLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVV- 254
            +G A+ +     S ASS    P  +   +S        LP  +  S ST    P+ PV  
Sbjct: 2699 TGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPL-PVTD 2757

Query: 255  -------HPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKE 307
                   H T  P T  SS  T   D  P    D + AST    P P +S+ +  T    
Sbjct: 2758 ASSVSTGHATPLPLTSLSSVST--GDTTPLPVTDTSSASTGQATPLPVTSLSSVST---- 2811

Query: 308  STSGDKPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 363
               GD       TTP     TSSAS  + TS P T  S+         P           
Sbjct: 2812 ---GD-------TTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGH 2861

Query: 364  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIH--KFLTAGPSAFNITSLIS 421
              LLP          ++   + I    +  VT  S  S  H        PS+ +      
Sbjct: 2862 ATLLPV---------TDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATP 2912

Query: 422  QAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP-PVSSQPKV 480
                 ++ A   + +P+ +TS +S+   + +P    P T+T       +TP PV+S   V
Sbjct: 2913 LPVTDTSSASTGHANPLHVTSPSSASTGHATP---LPVTDTSSASTGHATPLPVTSLSSV 2969

Query: 481  S----TPVVKQGPVSQS---ATQQPV--TADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 531
            S    TP+    P S S    T  PV  T+    G     P +   S+S    +P P   
Sbjct: 2970 STGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTD 3029

Query: 532  SNSSNASNATVVPQNS-SARSTCSLTP 557
            ++S++   AT +P  S S+ ST   TP
Sbjct: 3030 TSSASTGQATPLPVTSLSSVSTGDTTP 3056



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 96/402 (23%), Positives = 150/402 (37%), Gaps = 46/402 (11%)

Query: 194  ATATSGFASGMEDKHSSDASS--LLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
            ++A++G A+ +     S AS+    P  +   +S        LP     S ST    P+ 
Sbjct: 2231 SSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPL- 2289

Query: 252  PVVHPT------ATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSS-------- 297
            PV  P+      ATP  V  +         P      + AST    P P +S        
Sbjct: 2290 PVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGH 2349

Query: 298  -VPAQKTERKESTSGDKPVSHSCTTPST--SSASGLNPTSAPPTSASAVPVSPVPQSPIP 354
              P   T+    ++GD     +   P T  SSAS  + T  P T AS+         P+ 
Sbjct: 2350 ATPLHVTDASSVSTGD-----TTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVT 2404

Query: 355  PLLQDPNLLRQLLP-------ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 407
                        LP       +   T +L  +NV  +         VT  S  S      
Sbjct: 2405 DTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTP 2464

Query: 408  TAGPSAFNITS------LISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTN 461
              G    ++++      L++ A+ +ST    + + P++  S AS+  +   P   TP  +
Sbjct: 2465 LPGTDTSSVSTGHTTPLLVTDASSVST--GDTTRLPVTSPSSASTGHTTPLPVTDTPSAS 2522

Query: 462  TVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS---ATQQPV--TADKQQGHEPVSPRSLQ 516
            T    PL  T   S   + +T +    P S S   AT  PV  T+    GH    P +  
Sbjct: 2523 TGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTST 2582

Query: 517  RSSSQRSPSPGPNHTSNSSNASNATVVP-QNSSARSTCSLTP 557
             S+S    +P P   + S++   AT +P  ++S+ ST   TP
Sbjct: 2583 SSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTP 2624



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 54/385 (14%)

Query: 206  DKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPS 265
            D  S     + P  + S +S        LP  +T S+ST          H T  P T  S
Sbjct: 1029 DTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTG---------HVTPLPVTSLS 1079

Query: 266  SPFTLQSDHQPKKSFDANGAST--LSKLP-TPTSSV------PAQKTERKESTSGD---- 312
            S  T   D  P    D + AST   + LP T TSSV      P   T+   +++G     
Sbjct: 1080 SAST--GDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSL 1137

Query: 313  -----KPVSHSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 363
                   VS   TTP      SSAS    T  P TS S+V       +P+P         
Sbjct: 1138 PVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDT--TPLPVTSPSSAST 1195

Query: 364  RQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIH--KFLTAGPSAFNITSLIS 421
                P L        ++   +         VT AS  S  H        PSA + T   +
Sbjct: 1196 GHATPLLV-------TDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAAS-TGHTT 1247

Query: 422  QAAQLSTQAQPSNQSPMSLTSDASSPRSYVS---PRISTPQTNTVPIKPLISTPPVSSQP 478
                  T +  + Q+   L +D SS  +  +   P  ST   +T  + PL  T P S+  
Sbjct: 1248 PLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAST 1307

Query: 479  KVSTPVVKQGPVSQSATQQ---PVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSS 535
              +TP+      S S       PVT+         +P  +  +SS  +    P H +++S
Sbjct: 1308 GHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDAS 1367

Query: 536  NAS--NATVVPQNS-SARSTCSLTP 557
            +AS   AT +P  S S+ ST   TP
Sbjct: 1368 SASTGQATPLPVTSLSSVSTGDTTP 1392



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 96/404 (23%), Positives = 158/404 (39%), Gaps = 51/404 (12%)

Query: 194  ATATSGFASGMEDKHSSDASS----LLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHP 249
            ++A++G  + +    +S AS+     LP  + S +S        LP  +T S+ST    P
Sbjct: 2983 SSASTGHTTPLPVTDTSSASTGQATALP--VTSTSSASTGDTTPLPVTDTSSASTGQATP 3040

Query: 250  IKPV--VHPTATPSTVP---SSPFTLQSDHQ-PKKSFDANGASTLSKLPTPTSSVPAQKT 303
            + PV  +   +T  T P   +SP +  + H  P    DA+ AST    P P +S+ +  T
Sbjct: 3041 L-PVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVST 3099

Query: 304  ERKESTSGDKPVS----HSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 357
                      P S    H+ + P   TSSAS  + TS P T  S+         P+    
Sbjct: 3100 GDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTS 3159

Query: 358  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT 417
                            L    S+V       +L    + AS        +T+  SA    
Sbjct: 3160 SSST------GDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGD 3213

Query: 418  SL---ISQAAQLST-QAQP-------------SNQSPMSLTSDASSPRSYVSPRISTPQT 460
            +    ++  + +ST  A P             + + P++  S AS+ ++   P  +T   
Sbjct: 3214 TTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSV 3273

Query: 461  NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS---ATQQPV--TADKQQGHEPVSPRSL 515
            +T    PL  T P S+    +TP+      S S   AT  PV  T+    GH    P + 
Sbjct: 3274 STGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTD 3333

Query: 516  QRSSSQRSPSPGPNHTSNSSNASNAT----VVPQNSSARSTCSL 555
              S+S    +P P  + +S++  + T     +P ++S   T +L
Sbjct: 3334 TSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTL 3377



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 92/389 (23%), Positives = 143/389 (36%), Gaps = 46/389 (11%)

Query: 206  DKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPV--VHPTATPSTV 263
            D  S       P  + S +S        LP  +T S+ST    P+ PV  +   +T  T 
Sbjct: 2005 DTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPL-PVTSLSSVSTGDTT 2063

Query: 264  P---SSPFTLQSDHQ-PKKSFDANGAST---LSKLPTPTSSVPAQKTERKESTSGDKPVS 316
            P   +SP +  + H  P    DA+  ST    S L T  SSV          T     +S
Sbjct: 2064 PLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASS-LS 2122

Query: 317  HSCTTP----STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA 372
               TTP    S SSAS  + T  P T  S+V        P+             LP    
Sbjct: 2123 TGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTD- 2181

Query: 373  TLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQP 432
            T   +  +     + +  +A+  QA+   +        PS+ +    I      ++ A  
Sbjct: 2182 TSSASTGHATPLPVTDTSSASTGQATPLPV------TSPSSASTGHAIPLLVTDTSSAST 2235

Query: 433  SNQSPMSLTSDASSPRSYVSP-------RISTPQTNTVPIK-----------PLISTPPV 474
               +P+ +TS +S+     +P        +ST    ++P+            PL  T P 
Sbjct: 2236 GQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPS 2295

Query: 475  SSQPKVSTPVVKQGPVSQS---ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 531
            S+    +TP+      S S   AT  PVT+         +P  +   SS  +    P H 
Sbjct: 2296 SASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHV 2355

Query: 532  SNSSNASNATVVP---QNSSARSTCSLTP 557
            +++S+ S     P    +SS+ S+   TP
Sbjct: 2356 TDASSVSTGDTTPLPVTSSSSASSGHTTP 2384



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 95/373 (25%), Positives = 140/373 (37%), Gaps = 62/373 (16%)

Query: 206  DKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPS 265
            D  S+      P  +   +S   D   RLP  +  S+ST          H T  P T  S
Sbjct: 3765 DTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTG---------HATPLPVTSTS 3815

Query: 266  SPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTP--S 323
            S  T   D  P    D +  ST      P +S       R  +++G     H+   P   
Sbjct: 3816 SAST--GDTTPLPVTDTSSVSTGHATSLPVTS-------RSSASTG-----HATPLPVTD 3861

Query: 324  TSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDI 383
            TSS S  + T  P TS S+V       +P+P             P +  T   + S  D 
Sbjct: 3862 TSSVSTGHATPLPVTSTSSVSTGHA--TPLPVTSPSSASTGHATP-VPVTSTSSASTGDT 3918

Query: 384  SKINEVLTAAVTQASLQSIIHK--FLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLT 441
            + +       VT AS  S  H        PS+ +     +     ++ A   + +P+ LT
Sbjct: 3919 TPL------PVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLT 3972

Query: 442  SDASSPRSYVSPRISTPQTNTVPIKPLIS------TP-PVSSQPKVSTPVVKQGPV---- 490
            S +S         +ST  T  +P+    S      TP PV+S   VST      PV    
Sbjct: 3973 SLSS---------VSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPS 4023

Query: 491  ---SQSATQQPVT--ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP- 544
               S   T  PVT  +    GH    P +   S+S    +P P   ++S++  +AT +P 
Sbjct: 4024 SASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPV 4083

Query: 545  QNSSARSTCSLTP 557
             ++S+ ST   TP
Sbjct: 4084 TDTSSASTGHATP 4096



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 99/386 (25%), Positives = 156/386 (40%), Gaps = 64/386 (16%)

Query: 194  ATATSGFASGME--DKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
            ++A++G A+ +   D  S   +   P  +   +S   D   RLP  +  S+ST    P+ 
Sbjct: 1751 SSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPL- 1809

Query: 252  PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
                    P T PSS  T   D  P    DA+ AST       T+S+P   T    ++SG
Sbjct: 1810 --------PVTSPSSAST--GDTTPLPVTDASSAST-----GDTTSLPV--TIPSSASSG 1852

Query: 312  DKPVSHSCTTPST--SSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPA 369
                 H+ + P T  SS S  + TS   T AS+  VS    +P+P  + D N        
Sbjct: 1853 -----HTTSLPVTDASSVSTGHATSLLVTDASS--VSTGDTTPLP--VTDTN-------- 1895

Query: 370  LQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQ 429
              +    + + + ++  + V T   T   + S +    T   +   +TS         + 
Sbjct: 1896 --SASTGDTTPLHVTDASSVSTGHATSLPVTS-LSSASTGDTTPLPVTS--------PSS 1944

Query: 430  AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP-PVSSQPKVST------ 482
            A   + +P+ +T  +S P  + +   S P T+   +    +TP PV+    VST      
Sbjct: 1945 ASSGHTTPLPVTDASSVPTGHAT---SLPVTDASSVSTGHATPLPVTDASSVSTGHATPL 2001

Query: 483  PVVKQGPVSQ-SATQQPVT--ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASN 539
            PV     VS   AT  PVT  +    G     P +   S+S    +P P  + +S +  +
Sbjct: 2002 PVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGD 2061

Query: 540  ATVVPQNS-SARSTCSLTPALAAHFS 564
             T +P  S S+ ST   TP L    S
Sbjct: 2062 TTPLPVTSPSSASTGHATPLLVTDAS 2087



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 87/381 (22%), Positives = 140/381 (36%), Gaps = 32/381 (8%)

Query: 203  GMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPST 262
            G E + +S ++S  P    + T  H         +   S  T    P       T+  + 
Sbjct: 750  GPEGQWTSASASTSPDTAAAMTHTHQ------AESTEASGQTQTSEPASSGSRTTSAGTA 803

Query: 263  VPSSPFTLQSDHQPKKSFDANGAST-LSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTT 321
             PSS     +     +    +G +T  S  P+  S      TE   +++     SH    
Sbjct: 804  TPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASA-----SHGAIP 858

Query: 322  PSTSSASGLNPTSAPPTSASAVPVS-PVPQS-PIPPLLQDPNLLRQLLPALQATLQLNNS 379
             ST  AS + P +  PT + A     P  QS P  P             A     + +  
Sbjct: 859  VSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRG 918

Query: 380  NVDISKINEVL-TAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPM 438
            +  IS  ++   T +    +  SI    LT+ P     T   S + +  T A  SN +P+
Sbjct: 919  SDTISLASQATDTFSTVPPTPPSITSTGLTS-PQTETHTLSPSGSGKTFTTALISNATPL 977

Query: 439  SLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP-PVSSQPKVSTPVVKQGPVSQSATQQ 497
             +T  +S+   + +P   T  ++   +    +TP PV+S   VST      PV+      
Sbjct: 978  PVTYASSASTGHTTPLHVTDASS---VSTGHATPLPVTSPSSVSTGHTTPLPVTD----- 1029

Query: 498  PVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP---QNSSARSTCS 554
              T+ +  GH  V+P  +   SS  +    P   +++S+AS   V P    + S+ ST  
Sbjct: 1030 --TSSESTGH--VTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGD 1085

Query: 555  LTPALAAHFSENLIKHVQGWP 575
             TP      S     H    P
Sbjct: 1086 TTPLPVTDTSSASTGHATSLP 1106



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 86/371 (23%), Positives = 142/371 (38%), Gaps = 43/371 (11%)

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPF 268
            S+D ++ LP  I S  S  +     LP  +T S+ST     +  +V  T++ ST  ++P 
Sbjct: 1434 STDHATSLPVTIPSAASTGHTTP--LPVTDTSSASTGQATSL--LVTDTSSVSTGDTTPL 1489

Query: 269  TLQSDHQ-------PKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSC-- 319
             + S          P      + AST    P P +S+ +  T          P S S   
Sbjct: 1490 PVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549

Query: 320  TTP----STSSASGLNPTSAP---PTSASAVPVSPVPQSPIPPLLQ-DPNLLRQLLPALQ 371
            TTP      SS S  + T  P   P+SAS    +P+P +      + D   L    P+  
Sbjct: 1550 TTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSA 1609

Query: 372  AT---LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST 428
            +T     L  ++   +   +     VT AS  S  H       +  ++TS         +
Sbjct: 1610 STGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHA------TPLHVTS--------PS 1655

Query: 429  QAQPSNQSPMSLTSDASSPRSYVSPR----ISTPQTNTVPIKPLISTPPVSSQPKVSTPV 484
             A   + +P+ +TS +S+   + +P     +S+  T+     P+      S+      PV
Sbjct: 1656 SASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPV 1715

Query: 485  VKQGPVSQS-ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV 543
                 VS    T  PVT+         SP  +  +SS  +    P   +++S+ S A   
Sbjct: 1716 TSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHAT 1775

Query: 544  PQNSSARSTCS 554
            P   +  S+ S
Sbjct: 1776 PLPVTGLSSAS 1786



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 79/320 (24%), Positives = 124/320 (38%), Gaps = 48/320 (15%)

Query: 194  ATATSGFASGMEDKHSSDASS--LLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
            ++ ++G A+ +    +S  S+    P  + S +S        +P   T S+ST    P+ 
Sbjct: 3863 SSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPL- 3921

Query: 252  PVVHPT------ATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV------- 298
            PV + +      ATP  V S     + D       DA+ AST    P P +S+       
Sbjct: 3922 PVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGD 3981

Query: 299  --PAQKTERKESTSGD---------KPVSHSCTTP----STSSASGLNPTSAPPTSASAV 343
              P   T+   +++G            VS   TTP      SSAS  + TS P T AS+ 
Sbjct: 3982 TTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASS- 4040

Query: 344  PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII 403
             VS    +P+P       +      +   T  L  ++   +         VT  S  S  
Sbjct: 4041 -VSTGHGTPLP-------VTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSAS-- 4090

Query: 404  HKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNT- 462
                T   +   +TSL S +   +T    S+ +  S T  + SP    +P ++TP   T 
Sbjct: 4091 ----TGHATPLPVTSLSSVSTGHATPLAVSSATSAS-TVSSDSPLKMETPGMTTPSLKTD 4145

Query: 463  VPIKPLISTPPVSSQPKVST 482
               +   S PP +SQ  +ST
Sbjct: 4146 GGRRTATSPPPTTSQTIIST 4165



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 76/301 (25%), Positives = 116/301 (38%), Gaps = 31/301 (10%)

Query: 70   SDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSN-NPSKTSDAP 128
            S STGH+    V T       G T+  P  N+ + S  H++  H ++PS+ +   TS  P
Sbjct: 3896 SASTGHATPVPV-TSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLP 3954

Query: 129  YDSADDWSEHISSSGKKYYYNCRTEVSQWEK-PKEWLEREQRQK-EANKMAVNSFPKDRD 186
               A   S   +           + VS  +  P    +       +A  + V S      
Sbjct: 3955 VTDASSAS---TGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 4011

Query: 187  YRREVMQATATSGFASGMEDKHS-SDASSL-----LPQNILSQTSRHNDRDYRLPRAETH 240
                 +  T  S  +SG       +DASS+      P  + S +S        LP  +T 
Sbjct: 4012 GDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071

Query: 241  SSSTPVQHPIKPVVHPT------ATPSTVPSSPFTLQSDHQPKKSFDANGASTLS----- 289
            S+ST    P+ PV   +      ATP  V S          P     A  AST+S     
Sbjct: 4072 SASTGHATPL-PVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPL 4130

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 349
            K+ TP  + P+ KT+    T+   P + S T  ST       P++A  T ++A P+  +P
Sbjct: 4131 KMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTI------PSTAMHTRSTAAPIPILP 4184

Query: 350  Q 350
            +
Sbjct: 4185 E 4185



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 94/404 (23%), Positives = 147/404 (36%), Gaps = 62/404 (15%)

Query: 206  DKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSST------PVQHPIKPVV-HPTA 258
            D  S+      P  + S +S        LP  +T S+ST      PV         H T 
Sbjct: 2789 DTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATP 2848

Query: 259  TPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP-TPTSSV------PAQKTERKESTSG 311
             P T  SS  T  +   P     +      + LP T TSS+      P   T    +++G
Sbjct: 2849 LPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTG 2908

Query: 312  DK---PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 368
                 PV+ + ++ ST  A+ L+ TS  P+SAS    +P+P +                 
Sbjct: 2909 HATPLPVTDT-SSASTGHANPLHVTS--PSSASTGHATPLPVTDTSSA------------ 2953

Query: 369  ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST 428
            +      L  +++      +     VT  S  S  H   T  P     ++   QA  L  
Sbjct: 2954 STGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHT--TPLPVTDTSSASTGQATALPV 3011

Query: 429  QAQPSNQS------PMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVST 482
             +  S  +      P++ TS AS+ ++   P  S    +T    PL  T P S+    +T
Sbjct: 3012 TSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 3071

Query: 483  PVVKQGPVSQS---ATQQPVT------------------ADKQQGHEPVSPRSLQRSSSQ 521
            P++     S S   AT  PVT                  +    GH    P +   S+S 
Sbjct: 3072 PLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSAST 3131

Query: 522  RSPSPGPNHTSNSSNASNATVVP-QNSSARSTCSLTPALAAHFS 564
               +  P   ++S+   + T +P  ++S+ ST   TP L    S
Sbjct: 3132 GDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETS 3175



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 73/344 (21%), Positives = 126/344 (36%), Gaps = 51/344 (14%)

Query: 239 THSSSTPVQHPIKPVVH-PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSS 297
           T S+ T  +     + H  T+TPS  PS                 N   T+S+  +P+  
Sbjct: 200 TRSTQTTRESQTSTLTHRTTSTPSFSPSVH---------------NVTGTVSQKTSPSGE 244

Query: 298 VPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 357
                     +TS       + TT + S+      TS+ P + S +PV+        P  
Sbjct: 245 TATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEG 304

Query: 358 QDPNLLRQLLPALQATLQLNN--SNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
           Q P    +           N+   +V+ ++++++ T      +L  +    + + PS FN
Sbjct: 305 QSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTL----NTLTPVTTSTVLSSPSGFN 360

Query: 416 ITSLISQAAQLSTQAQPSNQSPMSLTSDASS-----PRS-------------YVSPRIS- 456
            +  +SQ    S +   S+ S +S T   +S     P S              VS  IS 
Sbjct: 361 PSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISA 420

Query: 457 -TPQTNTVPIKPLIST--PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR 513
            T + +T+     +ST   P S  PK+ST    Q       T +P            SP 
Sbjct: 421 ITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRP------HERSSFSPG 474

Query: 514 SLQRSSSQRSPSPGPNHTSNSSNAS-NATVVPQNSSARSTCSLT 556
             Q   +    +  P+  S+  + + + T +P  S+  +T  +T
Sbjct: 475 VSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVT 518



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 83/404 (20%), Positives = 133/404 (32%), Gaps = 70/404 (17%)

Query: 192 MQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
           M  TATS  +S M D+H+S   +  P      ++ H+           HS+ST       
Sbjct: 589 MIKTATSPSSSPMLDRHTSQQITTAP------STNHST---------IHSTST------S 627

Query: 252 PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
           P   P  +      +P T Q     +         T++   TP SS  A      E    
Sbjct: 628 PQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVT---TPGSSFTASGHSPSEIVPQ 684

Query: 312 DKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVS-----------------------PV 348
           D P   + TT + +     + T AP T+  A P S                        V
Sbjct: 685 DAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSV 744

Query: 349 PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
             +P  P  Q  +      P   A +   +         +  T+    +  ++      T
Sbjct: 745 VSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTAT 804

Query: 409 AG--------PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT 460
                     PS     S   +  + S+     + +  S T   S+  S+ +  +ST   
Sbjct: 805 PSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMA 864

Query: 461 NTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
           ++  I P    P +S       P  +  P S SA+ Q   A  +           QR+ +
Sbjct: 865 SS--IVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMA-------QTQRTRT 915

Query: 521 QRSPSPGPNHTSNSSNASN--ATVVPQNSSARSTCSLTPALAAH 562
            R    G +  S +S A++  +TV P   S  ST   +P    H
Sbjct: 916 SR----GSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETH 955


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 84/412 (20%), Positives = 161/412 (39%), Gaps = 36/412 (8%)

Query: 172  EANKMAVNSFPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRD 231
            EAN ++                +++T+   S M     S+ S LL    +S T   +   
Sbjct: 1589 EANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVAS--- 1645

Query: 232  YRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKL 291
               P A T  S+TPV         P  T + V SSP   +    P  ++   G + L+ +
Sbjct: 1646 ---PEAST-LSTTPVDSN-----SPVITSTEVSSSPTPAEGTSMPTSTY-TEGRTPLTSI 1695

Query: 292  PTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS--AVPVSPVP 349
               T+ V +       +T  D     + +T + SS +    TS P ++ S    P++ +P
Sbjct: 1696 TVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIP 1755

Query: 350  QSPIPPLLQDPNLLRQL-----------LPALQATLQLNNSNVDISKINEVLTAAVTQAS 398
             S  P L  + + L                A  +      +++  S ++E +T   +   
Sbjct: 1756 VSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPV 1815

Query: 399  LQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTP 458
              +++     +  S  + T + S +  +++ A  S+ +P   TS A+S  S  S  +++ 
Sbjct: 1816 SHTLV---ANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSI 1872

Query: 459  QTNTVPI-----KPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR 513
              +T  +       L +TP V+S P  +   V   P +   +  P T+  ++G  P++  
Sbjct: 1873 PVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMP-TSTPREGRPPLTSI 1931

Query: 514  SLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSE 565
             +  +++  S       T+ +   +  T   Q SS+ +T   T      +SE
Sbjct: 1932 PVS-TTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSE 1982



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 68/288 (23%), Positives = 126/288 (43%), Gaps = 45/288 (15%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            S+TPV        +   T ST  SS  T+        S  + G++ LS +P  T+ V + 
Sbjct: 3420 STTPVDS------NTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASS 3473

Query: 302  KTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS--AVPVSPVPQSPIPPLLQD 359
            +     +T  D     + ++P+ SS +    TS P ++A   + P++ +P S  P    +
Sbjct: 3474 EASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSE 3533

Query: 360  PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
             + L        +T  ++ SN  ++  ++   A+ + A+LQ    +  T    + ++T++
Sbjct: 3534 ASTL--------STTPVD-SNTFVTSSSQ---ASSSPATLQVTTMRMSTPSEGSSSLTTM 3581

Query: 420  ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 479
            +  +  +++       S  S  S  S  RS  +P  ++ Q+N+ P  P + T P+S+  +
Sbjct: 3582 LLSSTYVTS-------SEASTPSTPSVDRS--TPVTTSTQSNSTPTPPEVITLPMSTPSE 3632

Query: 480  VSTPVVKQGPVSQSA---------------TQQPVTADKQQGHEPVSP 512
            VSTP+    PVS ++               T  PV    Q    PV+P
Sbjct: 3633 VSTPLTIM-PVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTP 3679



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 80/346 (23%), Positives = 136/346 (39%), Gaps = 52/346 (15%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV 315
            P  T S   SSP T      P  ++ + G++ L+ +P  T+ V + +     ST    PV
Sbjct: 1956 PVTTYSQASSSPTTADGTSMPTPAY-SEGSTPLTSMPLSTTLVVSSEA----STLSTTPV 2010

Query: 316  SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ 375
              S  TP+T+S  G   +S+P T+      +  P     PL   P     ++ +   TL 
Sbjct: 2011 DTS--TPATTSTEG---SSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLS 2065

Query: 376  LN--NSNVDISKINEVLTAAVTQASLQSII-----HKFLTAGPSAFNITSLIS-QAAQLS 427
                +S   ++   E  ++A  + S  +I         LT+ P   + T + S +A+ LS
Sbjct: 2066 TTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIP--LSTTPVASPEASTLS 2123

Query: 428  TQAQPSNQSPMSLTSDASSP-------------RSYVSPRISTPQTNTV----PIKPLIS 470
            T    SN   ++ T  +SSP                 +P  S P + TV     I  L +
Sbjct: 2124 TTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLST 2183

Query: 471  TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQ------RSSSQRSP 524
            TP  +S P  ++   +  P +   T  P T+   +G  P +   +         +S  S 
Sbjct: 2184 TPVDTSTPVTNSTEARSSPTTSEGTSMP-TSTPSEGSTPFTSMPVSTMPVVTSEASTLSA 2242

Query: 525  SPGPNHT--------SNSSNASNATVVPQNSSARSTCSLTPALAAH 562
            +P    T        ++S   +  T +P ++ +  T  LT    +H
Sbjct: 2243 TPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 87/327 (26%), Positives = 138/327 (42%), Gaps = 39/327 (11%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            S+TPV         P  T +   SSP T      P         ST S+  TP +S+P  
Sbjct: 709  STTPVDTST-----PVTTSTEASSSPTTADGASMP--------TSTPSEGSTPLTSMPVS 755

Query: 302  KT---ERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ 358
            KT     + ST    P+  S T  +TS+ +  +PT+   T  +++P+S  P    P L  
Sbjct: 756  KTLLTSSEASTLSTTPLDTS-THITTSTEASCSPTT---TEGTSMPIS-TPSEGSPLLTS 810

Query: 359  DPNLLRQLLPALQATLQLN--NSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNI 416
             P  +  +     +TL     +SN  ++   EV +++ T A   S+     + G +   +
Sbjct: 811  IPVSITPVTSPEASTLSTTPVDSNSPVTTSTEV-SSSPTPAEGTSMPTSTYSEGRTP--L 867

Query: 417  TSLISQAAQLSTQAQPSNQSPMSLTS-DASSPRSYVSPRISTPQTNTVPIKPLISTP--- 472
            TS+      ++T A     S +S T  D S+P +  +   S+P T+     P  STP   
Sbjct: 868  TSMPVSTTLVATSAI----STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT-STPGEG 922

Query: 473  --PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 530
              P++S P  +TPVV     + SAT    +       E  S  +    +S  + +P    
Sbjct: 923  STPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT 982

Query: 531  TSNSSNASNATVVPQNSSARSTCSLTP 557
            T  +S   + T+V   +S  ST S TP
Sbjct: 983  TPLTSTPVSHTLVA--NSEASTLSTTP 1007



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 83/325 (25%), Positives = 124/325 (38%), Gaps = 35/325 (10%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            S+TPV         P  T +   SSP T +    P         ST S+  TP +S P  
Sbjct: 945  SATPVDTST-----PVTTSTEATSSPTTAEGTSIP--------TSTPSEGTTPLTSTPVS 991

Query: 302  KT---ERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQ 358
             T     + ST    PV  +  TP T+S    +P   PPT+      +  P     PL +
Sbjct: 992  HTLVANSEASTLSTTPVDSN--TPLTTSTEASSP---PPTAEGTSMPTSTPSEGSTPLTR 1046

Query: 359  DPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITS 418
             P  +   + A   T  L+ +  D S          +QAS  S      +   S ++  S
Sbjct: 1047 MP--VSTTMVASSETSTLSTTPADTS----TPVTTYSQASSSSTTADGTSMPTSTYSEGS 1100

Query: 419  LISQAAQLSTQAQPSNQSPMSLTS--DASSPRSYVSPRISTPQT---NTVPIKPLIS-TP 472
                +  +ST+   S+++    T+  D S P +  +   S+P T    ++P  P    T 
Sbjct: 1101 TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTT 1160

Query: 473  PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTS 532
            P++S P  +T VV     + S T            E  SP      +S  + +PG   T 
Sbjct: 1161 PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220

Query: 533  NSSNASNATVVPQNSSARSTCSLTP 557
             +S     T  P  SS  ST S +P
Sbjct: 1221 LTSMPVRHT--PVASSEASTLSTSP 1243



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 94/393 (23%), Positives = 158/393 (40%), Gaps = 70/393 (17%)

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPF 268
            SS+AS+L    + ++T         L    T +SS+P           ++ P++ P    
Sbjct: 2647 SSEASTLSTTPVDTRT---------LVTTSTGTSSSPT------TAEGSSMPTSTPGERS 2691

Query: 269  TLQSDHQPKKSFDANG-ASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSS- 326
            T  ++     +  AN  ASTLS  P  TS+      E   S +  +  S   +TPS  S 
Sbjct: 2692 TPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGST 2751

Query: 327  ------------ASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT- 373
                        AS    T +     +++PV+   ++   P   +   +    P+  +T 
Sbjct: 2752 PLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTP 2811

Query: 374  ---LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQA 430
               + +N++ V  S+   + T  V  ++  +   K  ++  +A  I   IS A++ ST  
Sbjct: 2812 LTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLL 2871

Query: 431  QPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI---STP--------PVSSQPK 479
                  P+S T  ASS  S +S   +TP   ++P+       S+P        P+S+  +
Sbjct: 2872 ---TSIPVSTTPVASSEASTLS---TTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSE 2925

Query: 480  VSTP----VVKQGPVSQSA----------TQQPVTADKQQGHEPVSPRSLQRSSSQRSPS 525
            VSTP    +V   PV+ S           T+ PVT   +    P +       +S    +
Sbjct: 2926 VSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTT----AEGTSMPIST 2981

Query: 526  PGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 558
            PG   T  +S   + + +P  SS  ST S TPA
Sbjct: 2982 PGERRTPLTS--MSVSTMPVASSEASTLSRTPA 3012



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 86/362 (23%), Positives = 140/362 (38%), Gaps = 60/362 (16%)

Query: 242 SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
           S+TPV         P  T +   SS  T +    P  ++   G++ L+ +P  T+ V + 
Sbjct: 650 STTPVDSNT-----PVTTSTEATSSSTTAEGTSMPTSTY-TEGSTPLTSMPVNTTLVASS 703

Query: 302 KTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP----PTSASAVPVSPVPQSPIPPLL 357
           +     ST    PV  S T  +TS+ +  +PT+A     PTS  +   +P+   P+    
Sbjct: 704 EA----STLSTTPVDTS-TPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV---- 754

Query: 358 QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSII-----HKFLTAGPS 412
               LL     +  +T  L+ S    +      +   T+ +   I         LT+ P 
Sbjct: 755 -SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIP- 812

Query: 413 AFNITSLIS-QAAQLSTQAQPSNQSPMSLTSDASSPRS-----------------YVSPR 454
             +IT + S +A+ LST    SN    + T  +SSP                     S  
Sbjct: 813 -VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMP 871

Query: 455 ISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVS--P 512
           +ST    T  I  L +TP  +S P  ++   +  P +   T  P T+   +G  P++  P
Sbjct: 872 VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-TSTPGEGSTPLTSMP 930

Query: 513 RSLQR--SSSQRSPSPGPNHTS----------NSSNASNATVVPQNSSARSTCSLTPALA 560
            S     SS  R+ S  P  TS          +S   +  T +P ++ +  T  LT    
Sbjct: 931 DSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV 990

Query: 561 AH 562
           +H
Sbjct: 991 SH 992



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 92/361 (25%), Positives = 143/361 (39%), Gaps = 60/361 (16%)

Query: 209 SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPF 268
           SS+AS+L    + S+T              T +SS+P    +  +  PT+TPS   S+P 
Sbjct: 466 SSEASNLSTTPVDSKTQ---------VTTSTEASSSPPTAEVNSM--PTSTPSE-GSTPL 513

Query: 269 TLQS-DHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSA 327
           T  S    P  S +A   STLS  P  TS+     +E   S++  +  S   +TPS    
Sbjct: 514 TSMSVSTMPVASSEA---STLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPS---- 566

Query: 328 SGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKIN 387
            G  P +  P S   V  S    +   P                      +SN  ++  +
Sbjct: 567 EGSTPLTNMPVSTRLVVSSEASTTSTTPA---------------------DSNTFVTTSS 605

Query: 388 EVLTAAVTQASLQSIIHKFLTAGPSAFNI---TSLI--SQAAQLSTQAQPSNQSPMSLTS 442
           E  +++ T          +   G +  ++   T+L+  S+A+ LST    SN +P++ ++
Sbjct: 606 EASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSN-TPVTTST 664

Query: 443 DASSPRSYVSPRISTPQTNTVPIKPLISTP-----PVSSQPKV--STPVVKQGPVSQS-- 493
           +A+S  +          T T    PL S P       SS+     +TPV    PV+ S  
Sbjct: 665 EATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTE 724

Query: 494 ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTC 553
           A+  P TAD      P S  S    S+  +  P       SS AS  +  P ++S   T 
Sbjct: 725 ASSSPTTAD--GASMPTSTPS--EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITT 780

Query: 554 S 554
           S
Sbjct: 781 S 781



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 85/393 (21%), Positives = 153/393 (38%), Gaps = 44/393 (11%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV 315
            P  T S   SS  T      P  ++ + G++ L+ +P  T  V + +     +T  D  +
Sbjct: 1072 PVTTYSQASSSSTTADGTSMPTSTY-SEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI 1130

Query: 316  SHSCTTPSTSSASGLNPTSAP--PTSASAVPVSPVPQSPIPPLLQDPNLLRQL---LPAL 370
              + +T ++SS +    TS P  P S    P++ +P S    +  + N L          
Sbjct: 1131 PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQ 1190

Query: 371  QATLQLNNSNVDISKINEVLTAAVTQASL----QSIIHKFLTAGPSAFNITSLISQAAQL 426
             AT    +S    +++  + T+   + S       + H  + +  ++   TS +  +  +
Sbjct: 1191 VATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPV 1250

Query: 427  STQAQPSNQS--------PMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP 478
            +T A+ S+          P S TS+ S+  + +   +ST    +     L++TP  +  P
Sbjct: 1251 TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP--VSTTLVTSPEASTLLTTPVDTKGP 1308

Query: 479  KVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSP----RSLQRSS--SQRSPSPGPNHT- 531
             V++  V   P     T  P T+   +G  P++      +L  SS  S  S +P  N T 
Sbjct: 1309 VVTSNEVSSSPTPAEGTSMP-TSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP 1367

Query: 532  -------SNSSNASNATVVPQNSSARSTCSLT--PALAAHFSENLIKHVQGWPAD----- 577
                    +S   S  T +P ++ +  T  LT  P        +    +   P D     
Sbjct: 1368 VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG 1427

Query: 578  --HAEKQASRLREEAHNMGTIHMSEICTELKNL 608
               AE  +S    E  ++ T   SE  T LK++
Sbjct: 1428 TTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI 1460



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 87/376 (23%), Positives = 141/376 (37%), Gaps = 53/376 (14%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P      S+TPV      ++  T   S  P +  T  S   P     +   ST S+  TP
Sbjct: 3223 PLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTP 3282

Query: 295  TSSVPAQKT---ERKESTSGDKPVSHSCTTPSTSSASGLNP----TSAPPT--SASAVPV 345
             +S+P   T     + ST    P   S    + S AS   P    TS P +  S  + P+
Sbjct: 3283 LTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPL 3342

Query: 346  SPVPQSPIPPLLQDPNLL--------RQLLPALQATLQ---LNNSNVDISKINE----VL 390
            + +  S  P +  + + L          +  + +A+L       +++  S  +E    + 
Sbjct: 3343 TNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLA 3402

Query: 391  TAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY 450
            +  V+   + S     L+  P   N     S  A  S         P S TS+ S+P S 
Sbjct: 3403 SMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLS- 3461

Query: 451  VSPRISTP----QTNTVPIKPL-ISTPPVSSQPKVSTPVVKQ---------GPVSQSATQ 496
            + P  +TP    + +T+   P+  STP  +S P  S+P   +         G  S   T 
Sbjct: 3462 IMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTN 3521

Query: 497  QPVTADKQQGHE-------PVSPRSLQRSSSQRSPSPGP-------NHTSNSSNASNATV 542
             PV+       E       PV   +   SSSQ S SP           T +  ++S  T+
Sbjct: 3522 MPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM 3581

Query: 543  VPQNSSARSTCSLTPA 558
            +  ++   S+ + TP+
Sbjct: 3582 LLSSTYVTSSEASTPS 3597



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 82/359 (22%), Positives = 141/359 (39%), Gaps = 56/359 (15%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            S+TPV         P  T +   S P T +    P  S  + G + L+++P  T+ V + 
Sbjct: 2300 STTPVDSNT-----PFTTSTEASSPPPTAEGTSMPT-STSSEGNTPLTRMPVSTTMVASF 2353

Query: 302  KTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT-------SASAVPVSPVPQSPIP 354
            +T    +T  D     + T  +T S +G +PT+A  T       S  + P++ VP S +P
Sbjct: 2354 ETSTLSTTPAD-----TSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMP 2408

Query: 355  PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 414
             +  + +      P   +T    ++    S      T+  T    +      L + P   
Sbjct: 2409 VVSSEAS-THSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP--LASMP--V 2463

Query: 415  NITSLISQAAQLSTQAQPSNQSPMSLTSDASS----PRSYVSPRISTPQTNTVPIKPLIS 470
            + T ++S  A   +       +PM+ +++ASS        V P  +  + +T+     +S
Sbjct: 2464 STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVS 2523

Query: 471  TPPVSSQPKVST----------PVVKQGPVSQSATQQPVTADKQQGHE---------PVS 511
            T PV+S P+ ST          PVV    +S SAT    T+     +          PVS
Sbjct: 2524 TTPVAS-PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVS 2582

Query: 512  PRSLQRSSSQ---------RSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAA 561
             + L  S +            P      TS+S   +  T +P ++ +  + SLT  L +
Sbjct: 2583 TKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVS 2641



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 64/318 (20%), Positives = 130/318 (40%), Gaps = 23/318 (7%)

Query: 243 STPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQK 302
           +TPV+     +  P    +   SSP T +       S  + G++ L+++P     V + +
Sbjct: 238 TTPVE-----ISTPVTISAQASSSPTTAEGPSL-SNSAPSGGSTPLTRMPLSVMLVVSSE 291

Query: 303 TERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS--AVPVSPVPQSPIPPLLQDP 360
                +T     +    +T ++SS +    TS P ++ +  + P++  P S +P    + 
Sbjct: 292 ASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEM 351

Query: 361 NLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL- 419
           + L  + P   +TL   ++           ++  T A   S++   L+ G +   +T++ 
Sbjct: 352 STL-SITPVDTSTLVTTSTEP---------SSLPTTAEATSMLTSTLSEGSTP--LTNMP 399

Query: 420 ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 479
           +S     S++A  ++  P+   +  ++     S   +   T+     P   + P++S P 
Sbjct: 400 VSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPV 459

Query: 480 VSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASN 539
            +TPV      + S T  PV +  Q      +  S   +     P+  P+  S    + +
Sbjct: 460 STTPVASSEASNLSTT--PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMS 517

Query: 540 ATVVPQNSSARSTCSLTP 557
            + +P  SS  ST S TP
Sbjct: 518 VSTMPVASSEASTLSTTP 535



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 80/335 (23%), Positives = 133/335 (39%), Gaps = 51/335 (15%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDK-- 313
            P  T + V SSP   +    P  ++ + G + L+ +P  T+ V +       +T  D   
Sbjct: 1308 PVVTSNEVSSSPTPAEGTSMPTSTY-SEGRTPLTSIPVNTTLVASSAISILSTTPVDNST 1366

Query: 314  PVSHS---CTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 370
            PV+ S   C++P+TS  + + P S P  S    P++ +P S  P +  + + L    P  
Sbjct: 1367 PVTTSTEACSSPTTSEGTSM-PNSNP--SEGTTPLTSIPVSTTPVVSSEASTL-SATPVD 1422

Query: 371  QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF------NITSLISQAA 424
             +T    ++           T++ T A   SI     + G +        N     S+A+
Sbjct: 1423 TSTPGTTSAEA---------TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAS 1473

Query: 425  QLSTQAQPSNQSPMSLTSDASSPRSY--VSPRISTPQ------------TNTVP---IKP 467
             LST    SN   ++ T+ +SSP      S  ISTP             T TV    I  
Sbjct: 1474 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINS 1533

Query: 468  LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR--------SLQRSS 519
            L +TP V+S P  +       P +   T    T+   +G  P++          S + ++
Sbjct: 1534 LSTTPAVTSTPVTTYSQASSSPTTADGTSMQ-TSTYSEGSTPLTSLPVSTMLVVSSEANT 1592

Query: 520  SQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCS 554
               +P       + S+ AS++T    +S   ST S
Sbjct: 1593 LSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPS 1627



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 86/346 (24%), Positives = 133/346 (38%), Gaps = 64/346 (18%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFD------------- 281
            P A T  S+TPV         P  T + V SSP   +    P  ++              
Sbjct: 821  PEAST-LSTTPVDSN-----SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVST 874

Query: 282  ----ANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPP 337
                 +  STLS  P  TS+     TE + S             P+TS  + + PTS P 
Sbjct: 875  TLVATSAISTLSTTPVDTSTPVTNSTEARSS-------------PTTSEGTSM-PTSTP- 919

Query: 338  TSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQA 397
                + P++ +P S  P +  +   L    P   +T    ++    S      T+  T  
Sbjct: 920  -GEGSTPLTSMPDSTTPVVSSEARTL-SATPVDTSTPVTTSTEATSSPTTAEGTSIPTST 977

Query: 398  SLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST 457
              +      LT+ P +  + +  S+A+ LST    SN +P++ +++ASSP         T
Sbjct: 978  PSEGTTP--LTSTPVSHTLVA-NSEASTLSTTPVDSN-TPLTTSTEASSPP-------PT 1026

Query: 458  PQTNTVPIKPLISTPPVSSQPKVSTPV-VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQ 516
             +  ++P     STP   S P    PV       S+++T     AD      PV+  S  
Sbjct: 1027 AEGTSMP----TSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS---TPVTTYSQA 1079

Query: 517  RSSSQRSPSPGPNHTSNSSNASNATVVPQN-----SSARSTCSLTP 557
             SSS  +       ++ S  ++  T VP +     SS  ST S TP
Sbjct: 1080 SSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP 1125



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 113/522 (21%), Positives = 195/522 (37%), Gaps = 73/522 (13%)

Query: 62   SDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNP 121
            S +P +  +  T  ++A +  T    E    T  +P E S   +++  S +  ++P    
Sbjct: 2065 STTPVDSKTQVTNSTEASSSAT---AEGSSMTISAPSEGSPLLTSIPLSTTPVASPE--A 2119

Query: 122  SKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSF 181
            S  S  P DS    S  I+S          TEVS    P E    +       +  + S 
Sbjct: 2120 STLSTTPVDSN---SPVITS----------TEVSSSPIPTEGTSMQTSTYSDRRTPLTSM 2166

Query: 182  PKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHS 241
            P         +  T  +  A         D S+ +  +  +++S        +P +    
Sbjct: 2167 P---------VSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSE 2217

Query: 242  SSTP-VQHPIKPVVHPTATPSTVPSSPFTLQ-----SDHQPKKSFDANGAS----TLSKL 291
             STP    P+  +   T+  ST+ ++P         S         A G S    TLS+ 
Sbjct: 2218 GSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 2277

Query: 292  PTPTSSVPAQKT---ERKESTSGDKPVSHSCTTPSTSSASGLNPT---SAPPTSASAVPV 345
             TP +S+P   T     + ST    PV  +    +++ AS   PT   ++ PTS S+   
Sbjct: 2278 TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGN 2337

Query: 346  SPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDIS-KINEVLTAAVTQASLQSIIH 404
            +P+ + P+             + A   T  L+ +  D S  +     A  +  +      
Sbjct: 2338 TPLTRMPV----------STTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSM 2387

Query: 405  KFLTAGPSAFNITSL-ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT--- 460
               T    +  +TS+ +S    +S++A   + +P+    D S+P +  +   S+P T   
Sbjct: 2388 PTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPV----DTSTPVTTSTEASSSPTTAEG 2443

Query: 461  NTVPIK-PLISTPPVSSQPKVSTPVV--KQGPVSQSA--TQQPVTADKQQGHEPVSPRSL 515
             ++P   P   T P++S P  +TPVV  + G +S +   T  P+T   +    P +   +
Sbjct: 2444 TSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDI 2503

Query: 516  QRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
                S  S        S    +   +  P  S   ST S TP
Sbjct: 2504 VVPISTASEG------STLLTSIPVSTTPVASPEASTLSTTP 2539



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 97/419 (23%), Positives = 164/419 (39%), Gaps = 66/419 (15%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            S+ PV       V  TA  +++P +  T  S         +   ST S+  TP +S+P  
Sbjct: 2759 STLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818

Query: 302  KTERKESTSG---DKPVSHSCTTPSTSSASGLNPTSA-----PPTSAS-------AVPVS 346
             T    S +G     PV  S T  +TS+ +  +PT+A     P ++AS       ++PVS
Sbjct: 2819 HTPVASSEAGTLSTTPVDTS-TPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVS 2877

Query: 347  PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 406
              P +           +   +P   +T   ++          + T +     L SI+   
Sbjct: 2878 TTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSIL--- 2934

Query: 407  LTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY---VSPRISTPQTNTV 463
            ++  P A       S+A+ LST      ++P++ +++ASS  +     S  ISTP     
Sbjct: 2935 VSTVPVAG------SEASTLST-TPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987

Query: 464  PIKPL-ISTPPVSSQPKVS---TPVVKQGPVSQS--ATQQPVTAD--------KQQGHEP 509
            P+  + +ST PV+S    +   TP     PV+ S  A+  P TA+          +G  P
Sbjct: 2988 PLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTP 3047

Query: 510  V-------SPRSLQRSSS-------QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSL 555
            +       +P ++  +S+         SP       S+S   +  T +P ++ +  +  L
Sbjct: 3048 LTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPL 3107

Query: 556  T--PALAAHFSENLIKHVQGWPAD-------HAEKQASRLREEAHNMGTIHMSEICTEL 605
            T  P      + + I  +   P D         E  +S    E  +M T   SE  T L
Sbjct: 3108 TGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPL 3166



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 73/297 (24%), Positives = 128/297 (43%), Gaps = 48/297 (16%)

Query: 239  THSSSTPVQHPI-----------KPVVHPTA-TPSTVPSSPFTLQSDHQPKKSFDANGAS 286
            T  +STPV H +            PV   T  T ST  SSP           S  + G++
Sbjct: 983  TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGST 1042

Query: 287  TLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT--SASAVP 344
             L+++P  T+ V + +T    +T  D     +  + ++SS++  + TS P +  S  + P
Sbjct: 1043 PLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTP 1102

Query: 345  VSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIH 404
            ++ VP S             +L+ + +A+  L+ + VD S    V T+    +S  +   
Sbjct: 1103 LTSVPVS------------TRLVVSSEAS-TLSTTPVDTS--IPVTTSTEASSSPTTAEG 1147

Query: 405  KFLTAGPSAFNITSL----ISQAAQLSTQAQPSNQSP------MSLTSDASSP---RSYV 451
              +   P +   T L    +S    +S++A   + +P      ++ +++ASSP       
Sbjct: 1148 TSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVT 1207

Query: 452  SPRISTPQTNTVPI--KPLISTPPVSSQPKV--STPVVKQGPVSQSA--TQQPVTAD 502
            S   STP   + P+   P+  TP  SS+     ++PV    PV+ SA  +  P TA+
Sbjct: 1208 SMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE 1264



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 87/353 (24%), Positives = 144/353 (40%), Gaps = 56/353 (15%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP-----TS 296
            S+TPV   I     P  T +   SSP T +    P         ST S++ TP      S
Sbjct: 2890 STTPVDTSI-----PVTTSTEGSSSPTTAEGTSMP--------ISTPSEVSTPLTSILVS 2936

Query: 297  SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTS--------------ASA 342
            +VP   +E   ST    PV  + T  +TS+ +  +PT+A  TS              + +
Sbjct: 2937 TVPVAGSEA--STLSTTPVD-TRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMS 2993

Query: 343  VPVSPVPQSPIPPLLQDP----NLLRQLLPALQATLQLNNSNVDISKINEVLT--AAVTQ 396
            V   PV  S    L + P      +     A  +      + + IS  +E  T   ++  
Sbjct: 2994 VSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053

Query: 397  ASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQS--PMSLTSDASSPRSYVSPR 454
            ++    I +  T   +  +  S +  + ++S+   P+  +  P+S  S+ S+P + V P 
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGV-PV 3112

Query: 455  ISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVS--- 511
             +TP T++  I  L +TP  +S P  ++      P +   T  P T+   +G  P++   
Sbjct: 3113 STTPVTSSA-ISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMP-TSTPSEGSTPLTYMP 3170

Query: 512  -PRSLQRSSSQRSPSPGPNHTS----NSSNASNATVVPQNSSARSTCS--LTP 557
                L  SS   + S  P  TS     S+ A+++T     S   ST S  +TP
Sbjct: 3171 VSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTP 3223



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 71/326 (21%), Positives = 141/326 (43%), Gaps = 41/326 (12%)

Query: 242  SSTPV--QHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVP 299
            S+TP     P+      +++P+T   +          + S  + G++ L+ LP  T  V 
Sbjct: 1535 STTPAVTSTPVTTYSQASSSPTTADGTSM--------QTSTYSEGSTPLTSLPVSTMLVV 1586

Query: 300  AQKTERKESTSGDKPVSHSCTTPSTSS--ASGLNPTSAPPTSASAVPVSPVPQSPIPPLL 357
            + +     +T  D     + +T ++SS  A G + T + P+  S + ++ +P S  P   
Sbjct: 1587 SSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL-LTSIPVSTTPVAS 1645

Query: 358  QDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS----- 412
             + + L        +T  +++++  I+     ++++ T A   S+     T G +     
Sbjct: 1646 PEASTL--------STTPVDSNSPVITSTE--VSSSPTPAEGTSMPTSTYTEGRTPLTSI 1695

Query: 413  AFNITSLISQAAQLSTQAQPSNQSPMSLTSDA-SSPRSY--VSPRISTPQTNTVPIK--P 467
                T + S A    +     N +P++ +++A SSP +    S   STP   T P+   P
Sbjct: 1696 TVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIP 1755

Query: 468  LISTPPVSSQPKV--STPVVKQGPVSQS--ATQQPVTADKQQGHEPVSPRSLQRSSSQRS 523
            + +TP +SS+     +TP+    PV+ S  AT  P TA+       +   +L    +  +
Sbjct: 1756 VSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTS----IPTSTLSEGMTPLT 1811

Query: 524  PSPGPNHTSNSSNASNATVVPQNSSA 549
             +P  +    +S AS  +  P +S++
Sbjct: 1812 STPVSHTLVANSEASTLSTTPVDSNS 1837



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 89/328 (27%), Positives = 134/328 (40%), Gaps = 63/328 (19%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTE---RKESTSGD 312
            P  T +   SSP T +    P         ST S+  TP +S+P   T     + ST   
Sbjct: 3017 PVTTSTEASSSPTTAEGTGIP--------ISTPSEGSTPLTSIPVSTTPVAIPEASTLST 3068

Query: 313  KPV-SHSCTTPSTSSASGLNP---TSAP-------PTSASAVPVS--PVPQSPIPPLLQD 359
             PV S+S    ST  +S   P   TS P        T  + VPVS  PV  S I  L   
Sbjct: 3069 TPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 360  PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
            P  +    P   +T    +S+   S+   + T+  ++ S        LT  P +   T L
Sbjct: 3129 P--VDTSTPVTTSTEA--HSSPTTSEGTSMPTSTPSEGSTP------LTYMPVS---TML 3175

Query: 420  ISQAAQLSTQAQPSNQS-PMSLTSDASSPRSYVSPRI--STPQTNTVPIK--PLISTPPV 474
            +  +   +  A P + S P++ +++A+S  +     I  STP     P+   P+ +TP  
Sbjct: 3176 VVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVA 3235

Query: 475  SSQPKV--STPVVKQGPVSQS--ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 530
            SS+  +  +TPV    P++ S  A+  P TA+                +S  + +P    
Sbjct: 3236 SSEASILSTTPVDSNTPLTTSTEASSSPPTAE---------------GTSMPTSTPSEGS 3280

Query: 531  TSNSSNASNATVVPQNSSARSTCSLTPA 558
            T  +S   + T V   SS  ST S TPA
Sbjct: 3281 TPLTSMPVSTTTVA--SSETSTLSTTPA 3306



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 90/385 (23%), Positives = 146/385 (37%), Gaps = 71/385 (18%)

Query: 211  DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTL 270
            D S+ +  +  + +S        +P +     STP+ +       P +T   V S   TL
Sbjct: 3131 DTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM------PVSTMLVVSSEDSTL 3184

Query: 271  Q-----------SDHQPKKSFDANGASTLSKLP----TPTSSVPAQKT---ERKESTSGD 312
                        +  +   S  A G S  +  P    TP +SVP   T     + S    
Sbjct: 3185 SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILST 3244

Query: 313  KPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA 372
             PV  +  TP T+S      +S+PPT+      +  P     PL   P  +     A   
Sbjct: 3245 TPVDSN--TPLTTSTEA---SSSPPTAEGTSMPTSTPSEGSTPLTSMP--VSTTTVASSE 3297

Query: 373  TLQLNNSNVDISKINEVLTAAVTQ---ASLQSIIHKFLTAGPS-----AFNITSLISQAA 424
            T  L+ +  D S      + A +    A   S+     + G +     +F+ T ++S  A
Sbjct: 3298 TSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEA 3357

Query: 425  QLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPI-KPLISTPPVSSQPKVSTP 483
               +       +P++ +++AS     +SP  +T +  ++P   P   T P++S P  +TP
Sbjct: 3358 STLSTTPVDTSTPVTTSTEAS-----LSP--TTAEGTSIPTSSPSEGTTPLASMPVSTTP 3410

Query: 484  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSP----GPN-HTSNSSNAS 538
            VV     + S T             PV   +L  +S++ S SP    G +  TS +S  S
Sbjct: 3411 VVSSEVNTLSTT-------------PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGS 3457

Query: 539  N------ATVVPQNSSARSTCSLTP 557
                    +  P  SS  ST S TP
Sbjct: 3458 TPLSIMPLSTTPVASSEASTLSTTP 3482



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 83/332 (25%), Positives = 135/332 (40%), Gaps = 66/332 (19%)

Query: 235 PRAETHSSSTPVQHP------IKPVVHPT-ATPSTVPSSPFTLQSDHQPKKSFDANGAST 287
           P   T +S+ PV         I PV   T  T ST PSS  T         S  + G++ 
Sbjct: 335 PLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTP 394

Query: 288 LSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS------ 341
           L+ +P  T  V + +     ST+   PV  S T  +T+S +  +PT+A  TS +      
Sbjct: 395 LTNMPVSTILVASSEA----STTSTIPVD-SKTFVTTASEASSSPTTAEDTSIATSTPSE 449

Query: 342 -AVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQ 400
            + P++ +P S  P    + +               N S   +    +V T+  T+AS  
Sbjct: 450 GSTPLTSMPVSTTPVASSEAS---------------NLSTTPVDSKTQVTTS--TEAS-- 490

Query: 401 SIIHKFLTAGPSAFNITSL-ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQ 459
                   + P    + S+  S  ++ ST     + S M + S  +S  S      STP 
Sbjct: 491 --------SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPV 542

Query: 460 TNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPR---SLQ 516
           T +       +TP  +S P  STP       S+ +T  P+T      + PVS R   S +
Sbjct: 543 TTSSEASSSSTTPEGTSIP-TSTP-------SEGST--PLT------NMPVSTRLVVSSE 586

Query: 517 RSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
            S++  +P+      + SS AS+++   + +S
Sbjct: 587 ASTTSTTPADSNTFVTTSSEASSSSTTAEGTS 618



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 67/367 (18%), Positives = 131/367 (35%), Gaps = 51/367 (13%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            S+TPV +       P  T +   SSP T +    P  S  + G + L+ +P  T+ V + 
Sbjct: 1711 STTPVDNST-----PVTTSTEARSSPTTSEGTSMPN-STPSEGTTPLTSIPVSTTPVLSS 1764

Query: 302  KTERKESTSGDKPVSHSCTTPSTSS--------------ASGLNPTSAPPTS------AS 341
            +     +T  D     + +T +TSS              + G+ P ++ P S      + 
Sbjct: 1765 EASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSE 1824

Query: 342  AVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQS 401
            A  +S  P     P++    +     PA   ++  +  +   + +  +  +  T AS ++
Sbjct: 1825 ASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSET 1884

Query: 402  IIHKFLTAGPSAFNI-TSLISQAAQLSTQAQ--------------PSNQSPMSLTSDASS 446
                 L+  P+  +   +  +Q +   T A               P    P+S T+ ASS
Sbjct: 1885 ---NTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASS 1941

Query: 447  PRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQG 506
              + +S  ++  +T         S+P  +    + TP   +G    ++     T      
Sbjct: 1942 EINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSE 2001

Query: 507  HEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSEN 566
               +S   +  S+   + + G +  + +   S  T  P   +       TP      S  
Sbjct: 2002 ASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERT-------TPLAGMPVSTT 2054

Query: 567  LIKHVQG 573
            L+   +G
Sbjct: 2055 LVVSSEG 2061



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 79/318 (24%), Positives = 136/318 (42%), Gaps = 27/318 (8%)

Query: 261  STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCT 320
            S   SSP TLQ     + S  + G+S+L+ +   ++ V + +     + S D+    + +
Sbjct: 3552 SQASSSPATLQVTTM-RMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTS 3610

Query: 321  TPSTSSASGLNPTSAPPTSASAV--PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNN 378
            T S S+ +     + P ++ S V  P++ +P S     + +       LP   +T  + +
Sbjct: 3611 TQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTA-STLPVDTSTPVITS 3669

Query: 379  SNVDISKIN-EVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQA----QPS 433
            + V  S +  E  T  +   S  S      T   S   +TS  S+ + LST +     P 
Sbjct: 3670 TQVSSSPVTPEGTTMPIWTPSEGST--PLTTMPVSTTRVTS--SEGSTLSTPSVVTSTPV 3725

Query: 434  NQSPMSLTSDASSPRSYVSPRISTP-QTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQ 492
              S  +++S A+   + +S  +S P + +T+    L+ST PV+  P+ STP +     S 
Sbjct: 3726 TTSTEAISSSATLDSTTMS--VSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSM 3783

Query: 493  SAT------QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 546
            S T        P T +      P+S  S +RS+   +    P    + S AS  +  P +
Sbjct: 3784 SMTTASEGSSSPTTLEGTT-TMPMSTTS-ERSTLLTTVLISPISVMSPSEASTLSTPPGD 3841

Query: 547  SSARSTCSLTPALAAHFS 564
            +   ST  LT   A  FS
Sbjct: 3842 T---STPLLTSTKAGSFS 3856



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 8/135 (5%)

Query: 243  STPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQK 302
            STPV      V   T    + P    T  +      S      ST  +  TP  +  A  
Sbjct: 3943 STPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPL 4002

Query: 303  TERKESTSGDKP--VSHSCTTPSTSSASGLNPTSAPPTSASAV--PVSPVPQSPIPPLLQ 358
            T    ST+   P   S  CTT    SAS L+ TS P TS S    PV+P  +S  P  + 
Sbjct: 4003 TYVTMSTAPSTPRTTSRGCTT----SASTLSATSTPHTSTSVTTRPVTPSSESSRPSTIT 4058

Query: 359  DPNLLRQLLPALQAT 373
               +     PA  +T
Sbjct: 4059 SHTIPPTFPPAHSST 4073



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 96/452 (21%), Positives = 168/452 (37%), Gaps = 67/452 (14%)

Query: 197 TSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRA--ETHSSSTPVQHPIKPVV 254
           TS  +S   D     ++ + P    + +   +D     P +  +T S +TP    +    
Sbjct: 92  TSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDV---- 147

Query: 255 HPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLS-KLPTPTSSVPAQKTERKESTSGDK 313
            P +TPS    S         P  SF+A  + T    + TP +      T  + S+S   
Sbjct: 148 -PMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLT------TSTQASSSPTT 200

Query: 314 PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVS-PVPQSPIPPLLQDPNLLRQLLPALQA 372
           P   S T P ++++ G  P ++ P S   V  S  +     P  +  P  +     +   
Sbjct: 201 P--ESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPT 258

Query: 373 TLQ---LNNS-----NVDISKIN-EVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQA 423
           T +   L+NS     +  ++++   V+    ++AS        L+  P+A NI  + S  
Sbjct: 259 TAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEAST-------LSTTPAATNIPVITSTE 311

Query: 424 AQLSTQAQPSNQSPMSLTSDASSPRSYV---SPRISTPQTNTVPIKPL------------ 468
           A  S         P S  ++ S+P +     +  ++T + +T+ I P+            
Sbjct: 312 ASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEP 371

Query: 469 ISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE-------PVSPRSLQRSSSQ 521
            S P  +    + T  + +G  S   T  PV+       E       PV  ++   ++S+
Sbjct: 372 SSLPTTAEATSMLTSTLSEG--STPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASE 429

Query: 522 RSPSPGPNHTSNSSNASNATVVPQNSSARST---CSLTPALAAHFSENLIKHVQG--WPA 576
            S SP     + + + S AT  P   S   T    S TP  ++  S      V       
Sbjct: 430 ASSSP-----TTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT 484

Query: 577 DHAEKQASRLREEAHNMGTIHMSEICTELKNL 608
              E  +S    E ++M T   SE  T L ++
Sbjct: 485 TSTEASSSPPTAEVNSMPTSTPSEGSTPLTSM 516



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 39/143 (27%)

Query: 239  THSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV 298
            T   +TP      P+ +   T ST PS+P T               ASTLS   TP +S 
Sbjct: 3988 TKEFTTPAMTTAAPLTY--VTMSTAPSTPRTTSRGC-------TTSASTLSATSTPHTST 4038

Query: 299  --------PAQKTERKESTSGDK-----PVSHSCTTPSTS-SASGLNP------------ 332
                    P+ ++ R  + +        P +HS T P+TS S++ +NP            
Sbjct: 4039 SVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKP 4098

Query: 333  ----TSAPPTSASAVPVSPVPQS 351
                TS P  + +AVP +   +S
Sbjct: 4099 STRTTSFPTVTTTAVPTNTTIKS 4121


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 87/346 (25%), Positives = 134/346 (38%), Gaps = 35/346 (10%)

Query: 242 SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQ-----PKKSFDANGASTLSKLPTPTS 296
           SS+P+  P       +  P T+P++P +     Q     P      +   +L  LP+P +
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359

Query: 297 SVPAQKT--------ERKESTSGDKPVSHSCTTPSTSS-ASGLNPTSAPPTSASAVPVSP 347
           + P+Q T        +   S     P+S   T P  +  A  L P  APP+  ++ P+SP
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 419

Query: 348 VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVT-QASLQSIIHKF 406
           +  +P P   Q PN L   L  LQA      S    +  +   +  V+  A+  S     
Sbjct: 420 LA-TPSP---QAPNALAVHL--LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473

Query: 407 LTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTS---DASSPRSYVSPRISTPQTNTV 463
           L A P    +      +  +S  A P  Q+P  L +     + P     P ++TP    +
Sbjct: 474 LAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531

Query: 464 PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQP-VTADKQQGHEPVSPRSLQRSSSQR 522
           P  P          P  S P+    P++    Q P V A       P  P S    + +R
Sbjct: 532 PSPPASFPGQAPFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588

Query: 523 SPSPGPNHTSNSSNASNATV----VPQNSSARSTCSLTPALAAHFS 564
            P+PGP+ + +    + A       P + S  ST S  P LA H S
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSS 633



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 77/324 (23%), Positives = 117/324 (36%), Gaps = 58/324 (17%)

Query: 243 STPVQHPIKPVVHPT--ATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           +TP       +  PT  AT S +PS P +  +   P+    A     L   P+P +S P 
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPPLQAPPSPPASPPL 417

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASG-----LNPTSAPPTSASAVPVSPVPQSPIPP 355
                    + +    H    P +   S       +P ++PP S SA P S  P S   P
Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477

Query: 356 LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
            LQ P       P+  A+  ++ S     +    L A                       
Sbjct: 478 PLQVP-------PSPPASPPMSPSATPPPQAPPPLAAPPL-------------------- 510

Query: 416 ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVS 475
                 Q A+   QA P+  +P  L +  S P S+      +P   ++P+ PL +TPP  
Sbjct: 511 ------QLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSA-SLPMSPL-ATPPPQ 561

Query: 476 SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR-------SPSPGP 528
           + P ++ P+++  P        P +   Q    P +P      S  R        P P P
Sbjct: 562 APPVLAAPLLQVPP------SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615

Query: 529 NHTSNSSNASNATVVPQNSSARST 552
           +  S SS  S   +   +SSA ST
Sbjct: 616 SR-SPSSTLSGPDLAGHSSSATST 638



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 81/381 (21%), Positives = 129/381 (33%), Gaps = 24/381 (6%)

Query: 188 RREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQ 247
           R +  +A   S  ++G   + +S  +   P   +++ SR    +  LPR        P  
Sbjct: 144 RGKATEAPKRSALSAGAR-RDTSGPTPGTPSPAMARRSRAAGTEVGLPRP------APSA 196

Query: 248 HPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKE 307
            P  P   P  + S+      T  S    ++     G    +     +S+ P     R  
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256

Query: 308 STSGDKPVSHSCTTPSTSSASGLN----PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL 363
            ++   P   +   PS     GL     P   PP   +A  + P+  SP+        L 
Sbjct: 257 PSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314

Query: 364 RQLLPALQATLQLNNSNVDI-SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQ 422
            Q  P L AT   ++    + + +     +     SLQ++      A P +   TSL S 
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP--PATPPSQATTSLGSP 372

Query: 423 AAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQT--NTVPIKPLISTPPVSSQPKV 480
             Q +    PS       T    +P +   P +  P +   + P+ PL +  P    P  
Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP--QAPNA 430

Query: 481 STPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNA 540
               + Q P S   +             PVSP +   S +  S +  P     S  AS  
Sbjct: 431 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-- 488

Query: 541 TVVPQNSSARSTCSLTPALAA 561
              P + SA       P LAA
Sbjct: 489 --PPMSPSATPPPQAPPPLAA 507


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 84/379 (22%), Positives = 144/379 (37%), Gaps = 25/379 (6%)

Query: 237  AETHSSSTPVQHP---------IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGAST 287
            A T S++TP   P           P   PTAT S   SS     +   P  +  A  ++ 
Sbjct: 4734 ASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA 4793

Query: 288  LSKLPTPTSSVPAQKTERKESTSGDKPVS--HSCTTPSTSSASGLNPTSAPPTSASAVPV 345
             S  P P+S++    T  +++T+    +S  H  +TP T+  S +  T A  T A++   
Sbjct: 4794 TSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTS 4853

Query: 346  SPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHK 405
            +P        +L +         A   T   +++      + E+ T A T AS  S    
Sbjct: 4854 TPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGS---- 4909

Query: 406  FLTAGPSAF-NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVP 464
              TA PS+    T ++++ +  +T   P+  +  + ++ A++   +VS   +TP   +  
Sbjct: 4910 --TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK 4967

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
              P  S    ++ P + +        S +A                +  +   S++  S 
Sbjct: 4968 ATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 5027

Query: 525  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQAS 584
            +P   HTS    A+  T     S A  T S TP   AH ++       G+ A  +    +
Sbjct: 5028 TPETVHTSTVLTATATTTGATGSVA--TPSSTPG-TAHTTKVPTTTTTGFTATPSSSPGT 5084

Query: 585  RLREEA----HNMGTIHMS 599
             L          M TIH S
Sbjct: 5085 ALTPPTTTPMSTMSTIHTS 5103



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 81/356 (22%), Positives = 135/356 (37%), Gaps = 35/356 (9%)

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES 308
            P  P    TATPS+ P + + L      K +  A   ++     TPTS++      +  +
Sbjct: 2579 PSTPATSSTATPSSTPGTTWIL-----TKPTTTATTTASTGSTATPTSTLRTAPPPKVLT 2633

Query: 309  TSGDKP-VSHSCTTPSTS--SASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 365
            T+   P V+ S  TPS+S  +A+ L    +  T+ +A  V+P+P S +        L + 
Sbjct: 2634 TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTW--TRLSQT 2691

Query: 366  LLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQ 425
              P    +    +S  + +  + VLTA  T       +     A PS+   T+  ++   
Sbjct: 2692 TTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSV-----ATPSSTPGTAHTTKVPT 2746

Query: 426  LSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVV 485
             +T       +P S    A +P  ++S   +TP T    + P  S P  +    V T   
Sbjct: 2747 TTTTG--FTATPSSSPGTALTPPVWIS-TTTTPTTRGSTVTP-SSIPGTTHTATVLTTTT 2802

Query: 486  KQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPN-----HTSNSSNASNA 540
                    AT    T      H P  P ++  +  +  P   P+      TS +S     
Sbjct: 2803 TTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2862

Query: 541  TVVPQNSSARS-TCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGT 595
            T + + S+  S T + T     H +          PA  +   +SR  E   + GT
Sbjct: 2863 THITEPSTVTSHTLAATTGTTQHST----------PALSSPHPSSRTTESPPSPGT 2908



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 87/377 (23%), Positives = 145/377 (38%), Gaps = 49/377 (12%)

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGA-STLSKLP-----------TPTS 296
            P  P    TATPS+ P + + L        + ++ G+ +T S  P           T T 
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259

Query: 297  SVPAQKT---ERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP------------PTSAS 341
            +VP   T      ++T+G   VS + TTP+ +S S   P S+P             T+ +
Sbjct: 4260 TVPTGSTATASSTQATAGTPHVSTTATTPTVTS-SKATPFSSPGTATALPALRSTATTPT 4318

Query: 342  AVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQS 401
            A   + +P S +        L +   P    +    +S  + +  + VLT   T      
Sbjct: 4319 ATSFTAIPSSSLGTTW--TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATG 4376

Query: 402  IIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTN 461
             +     A PS+   T+  ++    +T       +P S    A +P  ++S   +TP T+
Sbjct: 4377 SV-----ATPSSTPGTAHTTKVPTTTTTG--FTVTPSSSPGTARTPPVWIS-TTTTPTTS 4428

Query: 462  TVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQ 521
               + P  S P  +  P V T           AT    T      H P  P +   ++  
Sbjct: 4429 GSTVTP-SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNT-TATTHG 4486

Query: 522  RSPSPGPNHTSNS--SNASNATVVPQNSSARST-CSLTPALAAHFSENLIKHVQGWPADH 578
            RS SP   HT  +  ++A++ T+   + +  ST  S TPA     +++        PA  
Sbjct: 4487 RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH------STPALS 4540

Query: 579  AEKQASRLREEAHNMGT 595
            +   +SR  E   + GT
Sbjct: 4541 SPHPSSRTTESPPSPGT 4557



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 74/344 (21%), Positives = 126/344 (36%), Gaps = 44/344 (12%)

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTL----------SKLPTPTSSV 298
            P  P    TATPS+ P + + L        +    G++ +           K+ T T++ 
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3614

Query: 299  PAQKTERKESTSGDK-----PVSHSCTTPSTSSA--------SGLNPTSAPPTSASAVPV 345
            P   + +  S+S  +     PV  S  T ST+++         G   T    T+     +
Sbjct: 3615 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3674

Query: 346  SPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK---INEVLTAAVTQASLQSI 402
            S +  S  P       +L       +AT  ++  +        + E+ TAA T A+    
Sbjct: 3675 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP- 3733

Query: 403  IHKFLTAGPSAF-NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTN 461
                 TA PS+    T ++++ +  +T   P+       T+ ASS R+          T 
Sbjct: 3734 -----TATPSSTPGTTWILTEPSTTATVTVPTGS-----TATASSTRATAGTLKVLTSTA 3783

Query: 462  TVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSS-- 519
            T P   + S    SS P  +T +      + + T   VTA           R  Q ++  
Sbjct: 3784 TTP-TVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3842

Query: 520  ---SQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALA 560
               S  +PS  P     S+  +  T   + + + +T S TP  A
Sbjct: 3843 ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTA 3886



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 81/354 (22%), Positives = 134/354 (37%), Gaps = 48/354 (13%)

Query: 257  TATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVS 316
            TATPS+ P + + L               ST + +  PT S     +   ++T+G   VS
Sbjct: 3090 TATPSSTPGTTWILTE------------PSTTATVTVPTGSTATASS--TQATAGTPHVS 3135

Query: 317  HSCTTPSTSSASGLNPTSAP------------PTSASAVPVSPVPQSPIPPLLQDPNLLR 364
             + TTP+ +S S   P S+P             T+ +A   + +P S +        L +
Sbjct: 3136 TTATTPTVTS-SKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW--TRLSQ 3192

Query: 365  QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAA 424
               P    +    +S  +    + VLT   T       +     A PS+   T+  ++  
Sbjct: 3193 TTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSV-----ATPSSTPGTAHTTKV- 3246

Query: 425  QLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPV 484
             L+T       +P S    A +   ++S   +TP T    + P  S P  +  P V T  
Sbjct: 3247 -LTTTTTGFTATPSSSPGTARTLPVWIS-TTTTPTTRGSTVTP-SSIPGTTHTPTVLTTT 3303

Query: 485  VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNS--SNASNATV 542
                     AT    T      H P  P +   ++  RS SP   HT  +  ++A++ T+
Sbjct: 3304 TTTVATGSMATPSSSTQTSGTTHTPPVPNT-TATTHGRSLSPSSPHTVRTAWTSATSGTL 3362

Query: 543  VPQNSSARST-CSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGT 595
               + +  ST  S TPA     +++        PA  +   +SR  E   + GT
Sbjct: 3363 GTTHITEPSTGTSHTPAATTGTTQH------STPALSSPHPSSRTTESPPSPGT 3410



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 83/399 (20%), Positives = 149/399 (37%), Gaps = 45/399 (11%)

Query: 196  ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH 255
            AT+   +G     SS   +  P  +L+ T+           ++  SSS+P      PV+ 
Sbjct: 3583 ATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT----SSKATSSSSPRTATTLPVLT 3638

Query: 256  PTATPST----VPSSPFTLQSDHQPKKSFDANGA--STLSKLPTP-TSSVPAQKTERKES 308
             TAT ST     P   FTL +     +      A  ST+    TP T+      T +  +
Sbjct: 3639 STATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATT 3698

Query: 309  TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 368
            T     +S   +TP T+       T+A  T+A+    +P        +L +P+    +  
Sbjct: 3699 TRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTV 3758

Query: 369  ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG--------------PSAF 414
               +T   +++      +  + + A T   + S      + G              P+A 
Sbjct: 3759 PTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTAT 3818

Query: 415  NITSLISQA-----AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI 469
            ++T++ S +      +LS    P+  + MS  + +S+P +  +  + T  T T      +
Sbjct: 3819 SVTAIPSSSLGTAWTRLSQTTTPT--ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSV 3876

Query: 470  STPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPV-----SPRSLQRSSSQRSP 524
            +TP  SS P  +         +   T  P ++       PV     +  + + S+   S 
Sbjct: 3877 ATP--SSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSS 3934

Query: 525  SPGPNHTSNSSNASNATV------VPQNSSARSTCSLTP 557
             PG  HT+     +  TV       P +S+  S  + TP
Sbjct: 3935 IPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTP 3973



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 79/359 (22%), Positives = 131/359 (36%), Gaps = 73/359 (20%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV 315
            PTATPS+ P + + L               ST + +  PT S     + R  +T+G   V
Sbjct: 3733 PTATPSSTPGTTWILTEP------------STTATVTVPTGSTATASSTR--ATAGTLKV 3778

Query: 316  SHSCTTPSTSSASGLNPTSAPPTSAS------------AVPVSPVPQSPIPPLLQDPNLL 363
              S  T  T  +S   P+S+P T+ +            A  V+ +P S +        L 
Sbjct: 3779 LTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWT--RLS 3836

Query: 364  RQLLPALQATLQLNNSNVDISKINEVLT----------AAVTQASLQSIIHKF------- 406
            +   P    +    +S  +    + VLT          +  T +S     H         
Sbjct: 3837 QTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTT 3896

Query: 407  --LTAGPSAFNITSLISQAAQLSTQAQPSNQ----SPMSL------------TSDASSPR 448
               TA PS+   T+L +    +ST   P+ +    +P S+            T+   +  
Sbjct: 3897 TGFTATPSSSPGTAL-TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3955

Query: 449  SYVSPRISTPQ---TNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA----TQQPVTA 501
            S  +P  ST     T+T P+    +T    S P  S   V+    S ++    T      
Sbjct: 3956 SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 4015

Query: 502  DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS--SARSTCSLTPA 558
                 H P +  S  + S+    SP P+  +  S  S  T  P ++  ++R+T + TP+
Sbjct: 4016 STVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPS 4074



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 78/362 (21%), Positives = 129/362 (35%), Gaps = 70/362 (19%)

Query: 257  TATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVS 316
            T T +T  S+  T      P  ++     ST + +  PT S     +   ++T+G   VS
Sbjct: 3078 TTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASST--QATAGTPHVS 3135

Query: 317  HSCTTPSTSSASGLNPTSAPPTSAS------------AVPVSPVPQSPIPPLLQDPNLLR 364
             + TTP+ +S+    P S+P T+ +            A   + +P S +        L +
Sbjct: 3136 TTATTPTVTSSKA-TPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT--RLSQ 3192

Query: 365  QLLPALQATLQLNNSNVDISKINEVLT----------AAVTQASLQSIIH--KFLTAGPS 412
               P    +    +S  +    + VLT          +  T +S     H  K LT   +
Sbjct: 3193 TTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTT 3252

Query: 413  AFNITSLISQAAQ------LSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIK 466
             F  T   S          +ST   P+ +   S  + +S P +  +P + T  T TV   
Sbjct: 3253 GFTATPSSSPGTARTLPVWISTTTTPTTRG--STVTPSSIPGTTHTPTVLTTTTTTVATG 3310

Query: 467  PLIS------------TPPV--------------SSQPKVSTPVVK--QGPVSQSATQQP 498
             + +            TPPV              SS   V T       G +  +   +P
Sbjct: 3311 SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP 3370

Query: 499  VTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA--RSTCSLT 556
             T      H P +     + S+    SP P+  +  S  S  T  P ++ A  R+T + T
Sbjct: 3371 STGTS---HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATAT 3427

Query: 557  PA 558
            P+
Sbjct: 3428 PS 3429



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 67/315 (21%), Positives = 122/315 (38%), Gaps = 41/315 (13%)

Query: 257  TATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVS 316
            TATPS+ P + + L               ST + +  PT S     +   ++T+G   VS
Sbjct: 4910 TATPSSTPGTTWILTE------------PSTTATVTVPTGSTATASS--TQATAGTPHVS 4955

Query: 317  HSCTTPSTSSASGLNPTSAP------------PTSASAVPVSPVPQSPIPPLLQDPNLLR 364
             + TTP+ +S S   P+S+P             T+ +A   + +P S +        L +
Sbjct: 4956 TTATTPTVTS-SKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW--TRLSQ 5012

Query: 365  QLLPALQATLQLNNSNVDISKINEVLTA-AVTQASLQSIIHKFLTAGPSAFNITSLISQA 423
               P    +    +S  +    + VLTA A T  +  S+     T G +    T+ +   
Sbjct: 5013 TTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAH---TTKVPTT 5069

Query: 424  AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTP 483
                  A PS+    +LT   ++P S +S   ++    T     +++T    ++   ST 
Sbjct: 5070 TTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTA 5129

Query: 484  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV 543
                 P S   T + +T    +     +  +   S++  S +PG        +     +V
Sbjct: 5130 T----PSSTLGTTRILT----ELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMV 5181

Query: 544  PQNSSARSTCSLTPA 558
            P  S+A ++ +L  A
Sbjct: 5182 PTGSTATASSTLGTA 5196



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 74/313 (23%), Positives = 112/313 (35%), Gaps = 33/313 (10%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            SSTP       V+  TAT +    S  T  S      +      +T     TP+SS    
Sbjct: 4353 SSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTA 4412

Query: 302  KTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPN 361
            +T          PV  S TT  T+S S + P+S P T+ +   ++    +     +  P+
Sbjct: 4413 RT---------PPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPS 4463

Query: 362  LLRQLL------PALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
               Q        P    T   +  ++  S  + V T A T A+  ++    +T   +   
Sbjct: 4464 SSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRT-AWTSATSGTLGTTHITEPSTG-- 4520

Query: 416  ITSLISQAAQLSTQ-AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPV 474
             TS    A   +TQ + P+  SP   +    SP    SP  +TP   T   +   +  P 
Sbjct: 4521 -TSHTPAATTGTTQHSTPALSSPHPSSRTTESP---PSPGTTTPGHTTATSRTTATATPS 4576

Query: 475  SSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTS 532
             ++     P         S T  P+T     G EP    S  L  S     PS G   T 
Sbjct: 4577 KTRTSTLLP--------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 4628

Query: 533  NSSNASNATVVPQ 545
            ++  A+   V  Q
Sbjct: 4629 SNIRAAGGAVCEQ 4641



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 17/170 (10%)

Query: 194  ATATSGFASGMEDKHSS-DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKP 252
            +T T+   SG     SS   ++  P  + + T+         P + T +S T    P+  
Sbjct: 4420 STTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPN 4479

Query: 253  VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS------------SVPA 300
                T   S  PSSP T+++      S    G + +++  T TS            S PA
Sbjct: 4480 TTATTHGRSLSPSSPHTVRTAWTSATS-GTLGTTHITEPSTGTSHTPAATTGTTQHSTPA 4538

Query: 301  QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT---SASAVPVSP 347
              +    S + + P S   TTP  ++A+     +A P+   +++ +P SP
Sbjct: 4539 LSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSP 4588



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P + T +S T    P+   +  T   S  PSSP T+++      S    G + +++  T 
Sbjct: 2813 PSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS-GILGTTHITEPSTV 2871

Query: 295  TS------------SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT---S 339
            TS            S PA  +    S + + P S   TTP  ++A+     +A P+   +
Sbjct: 2872 TSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRT 2931

Query: 340  ASAVPVSP 347
            ++ +P SP
Sbjct: 2932 STLLPSSP 2939



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 63/303 (20%), Positives = 106/303 (34%), Gaps = 17/303 (5%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            SSTP       V+  TAT +    S  T  S      +      +T     TP+SS    
Sbjct: 5026 SSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 5085

Query: 302  KTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPN 361
             T    +        H+ +TP T+  S +  T+A  T A+    +P        +L +  
Sbjct: 5086 LTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELT 5145

Query: 362  LLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS-AFNITSLI 420
                   A  +T  L+++      + E  T A       S      T G +    + + +
Sbjct: 5146 TTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTM 5205

Query: 421  SQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV-PIKPL------ISTPP 473
            +     +    PS+ +  +  + A  P S  +  +ST  ++ +  ++P        STP 
Sbjct: 5206 ATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPC 5265

Query: 474  --------VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPS 525
                     S    +     + G    +   Q    D+ QG  P SP  +  S+   SPS
Sbjct: 5266 FCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVS-SAPLSSPS 5324

Query: 526  PGP 528
            P P
Sbjct: 5325 PAP 5327



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 16/128 (12%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P + T +S T    P+      T   S  PSSP T+++      S    G + +++  T 
Sbjct: 3315 PSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATS-GTLGTTHITEPSTG 3373

Query: 295  TS------------SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT---S 339
            TS            S PA  +    S + + P S   TTP  + A+     +A P+   +
Sbjct: 3374 TSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRT 3433

Query: 340  ASAVPVSP 347
            ++ +P SP
Sbjct: 3434 STLLPSSP 3441



 Score = 33.1 bits (74), Expect = 0.82
 Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 16/128 (12%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P + T +S T    P+      T   S  PSSP T+++      S    G + +++  T 
Sbjct: 3960 PSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATS-GILGTTHITEPSTV 4018

Query: 295  TSSVPAQKTERKE------------STSGDKPVSHSCTTPSTSSASGLNPTSAPPT---S 339
            TS  PA  T   +            S + + P S   TTP  +  +     +A P+   +
Sbjct: 4019 TSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT 4078

Query: 340  ASAVPVSP 347
            ++ +P SP
Sbjct: 4079 STLLPSSP 4086



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 49/234 (20%), Positives = 94/234 (40%), Gaps = 37/234 (15%)

Query: 191  VMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPI 250
            V+ ATAT+  A+G     SS   +     + + T+             T  ++TP   P 
Sbjct: 5037 VLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT-------------TGFTATPSSSPG 5083

Query: 251  KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTS 310
              +  PT TP +  S   T+ +   P+ +  +   +T + +   T+S     T    ST 
Sbjct: 5084 TALTPPTTTPMSTMS---TIHTSSTPETTHTSTVLTTTATMTRATNS-----TATPSSTL 5135

Query: 311  G-DKPVSHSCTTPSTSSASGLNPT--SAPPTSASAVPVSPVPQSPIPP-----------L 356
            G  + ++   TT +T++A+G   T  S P T+      S +    +P             
Sbjct: 5136 GTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGT 5195

Query: 357  LQDPNLLRQL--LPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
               P ++  +  +P   A+   ++S V  ++   VL +++   S+ ++    LT
Sbjct: 5196 AHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLT 5249



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 313  KPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP-QSPIPP 355
            K ++ +   P +       PT  PPT++ A PVS  P  +P PP
Sbjct: 5581 KDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP 5624


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 84/371 (22%), Positives = 136/371 (36%), Gaps = 44/371 (11%)

Query: 197  TSGFASGMEDKHS-SDASSLLPQNILSQTSRHNDRDY------RLPRAETHSSSTPVQHP 249
            TS    G + + S     +++P  +  Q S   DR        +  R   + SS     P
Sbjct: 1183 TSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP 1242

Query: 250  IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKEST 309
            + P   P   PST    P T +  +Q  +     G    S + TP   VP    E + ST
Sbjct: 1243 VVPTA-PELQPSTSTDQPVTSEPTYQATR-----GRKNRSSVKTPEPVVPTAP-ELRPST 1295

Query: 310  SGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPA 369
            S D+PV+   T+ +T S + ++    P T     P   +  S   P+   P         
Sbjct: 1296 STDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRT 1355

Query: 370  LQATLQLNNSNVDI-------SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQ 422
              ++++   S V I       +   + +T   T  + +    K  ++G +   +     +
Sbjct: 1356 NMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRG--RKNRSSGKTPETLVPTAPK 1413

Query: 423  AAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVST 482
                ++  QP    P S  +   + RS     + TP+T  VP  P +     + QP    
Sbjct: 1414 LEPSTSTDQPVTPEPTSQATRGRTNRS----SVKTPET-VVPTAPELQPSTSTDQPVTPE 1468

Query: 483  PV--VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP---SPGPNHTSNSSNA 537
            P     +G   +S+ + P T        P +P  LQ S+S   P    P    T    N 
Sbjct: 1469 PTSQATRGRTDRSSVKTPETV------VPTAP-ELQASASTDQPVTSEPTSRTTRGRKNR 1521

Query: 538  SNA----TVVP 544
            S+     TVVP
Sbjct: 1522 SSVKTPETVVP 1532



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 78/353 (22%), Positives = 126/353 (35%), Gaps = 52/353 (14%)

Query: 236  RAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPT 295
            R  T+ SS      + P   P   PST    P T +   Q  +     G +  S + TP 
Sbjct: 1434 RGRTNRSSVKTPETVVPTA-PELQPSTSTDQPVTPEPTSQATR-----GRTDRSSVKTPE 1487

Query: 296  SSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP-----------PTSASAVP 344
            + VP    E + S S D+PV+   T+ +T      +    P           P++++  P
Sbjct: 1488 TVVPTAP-ELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1546

Query: 345  VSPVPQS-------------------PIPPLLQDPNLLRQLL---PALQAT-LQLNNSNV 381
            V+P P S                   PI P LQ      QL+   P  +AT  + N S+V
Sbjct: 1547 VTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSV 1606

Query: 382  DISK--INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMS 439
               +  +        T ++ Q +  K  +         S +     +   A  S+  P +
Sbjct: 1607 KTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAA--SDLEPFT 1664

Query: 440  LTSDASSPRSYV------SPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVS-Q 492
             T  + +P +        + R ST +   VP  P   +P  + QP    P+ +   +  Q
Sbjct: 1665 PTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQ 1724

Query: 493  SATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQ 545
             A   P +      H+P S     +S + R+   G    + S  A      PQ
Sbjct: 1725 RAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQ 1777



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 86/362 (23%), Positives = 135/362 (37%), Gaps = 68/362 (18%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P+  T  SS     P      P   PST  + P T +   Q  +S      +  S + TP
Sbjct: 1105 PKIRTRKSSRMTPFPATSAA-PEPHPSTSTAQPVTPKPTSQATRS-----RTNRSSVKTP 1158

Query: 295  TSSVPAQKTERKESTSGDKPVS--------------HSCTTPST---------SSASGLN 331
               VP    E + STS D+PV+               S  TP T          S S   
Sbjct: 1159 EPVVPTAP-ELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDR 1217

Query: 332  PTSAPPTSAS-------AVPVSPVPQSPIPPLLQDPNLLRQLL---PALQATL-QLNNSN 380
            P ++ PTS +       +   +P P  P  P LQ      Q +   P  QAT  + N S+
Sbjct: 1218 PVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSS 1277

Query: 381  VDISKINEVLTAAVTQASLQSIIHKFLTAGP------SAFNITSLISQAAQLST----QA 430
            V   K  E +     +    +   + +T  P      S  N++S+ +    + T    Q 
Sbjct: 1278 V---KTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQI 1334

Query: 431  QPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVK--QG 488
              S   P++    + + RS  +        +TVPI P +     + QP    P  +  +G
Sbjct: 1335 STSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRG 1394

Query: 489  PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP------NHTSNSSNASNATV 542
              ++S+ + P T        P +P+    +S+ +  +P P        T+ SS  +  TV
Sbjct: 1395 RKNRSSGKTPETL------VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETV 1448

Query: 543  VP 544
            VP
Sbjct: 1449 VP 1450


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 94/371 (25%), Positives = 139/371 (37%), Gaps = 43/371 (11%)

Query: 221 LSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATP---------STVPSSPFTLQ 271
           LS  +R        PRA  H S  P    ++ +  P  TP           + SSP    
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298

Query: 272 SDHQPKKSFDANGASTLSKLPTPTSSVPAQKT--------ERKESTSGDKPVSHSCTTPS 323
           S   P      +   +L  LP+P ++ P+Q T        +   S     P+S   T P 
Sbjct: 299 SPSAPPSP---SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355

Query: 324 TSS-ASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVD 382
            +  A  L P  APP+  ++ P+SP+  +P P   Q PN L   L  LQA      S   
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLA-TPSP---QAPNALAVHL--LQAPFSPPPSPPV 409

Query: 383 ISKINEVLTAAVT-QASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLT 441
            +  +   +  V+  A+  S     L A P    +      +  +S  A P  Q+P  L 
Sbjct: 410 QAPFSPPASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLA 467

Query: 442 S---DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQP 498
           +     + P     P ++TP    +P  P          P  S P+    P++    Q P
Sbjct: 468 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---SPLATPPPQAP 524

Query: 499 -VTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATV----VPQNSSARSTC 553
            V A       P  P S    + +R P+PGP+ + +    + A       P + S  ST 
Sbjct: 525 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584

Query: 554 SLTPALAAHFS 564
           S  P LA H S
Sbjct: 585 S-GPDLAGHSS 594



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 77/324 (23%), Positives = 117/324 (36%), Gaps = 58/324 (17%)

Query: 243 STPVQHPIKPVVHPT--ATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           +TP       +  PT  AT S +PS P +  +   P+    A     L   P+P +S P 
Sbjct: 320 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPPLQAPPSPPASPPL 378

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASG-----LNPTSAPPTSASAVPVSPVPQSPIPP 355
                    + +    H    P +   S       +P ++PP S SA P S  P S   P
Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438

Query: 356 LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
            LQ P       P+  A+  ++ S     +    L A                       
Sbjct: 439 PLQVP-------PSPPASPPMSPSATPPPQAPPPLAAPPL-------------------- 471

Query: 416 ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVS 475
                 Q A+   QA P+  +P  L +  S P S+      +P   ++P+ PL +TPP  
Sbjct: 472 ------QLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSA-SLPMSPL-ATPPPQ 522

Query: 476 SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR-------SPSPGP 528
           + P ++ P+++  P        P +   Q    P +P      S  R        P P P
Sbjct: 523 APPVLAAPLLQVPP------SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576

Query: 529 NHTSNSSNASNATVVPQNSSARST 552
           +  S SS  S   +   +SSA ST
Sbjct: 577 SR-SPSSTLSGPDLAGHSSSATST 599



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 60/298 (20%), Positives = 102/298 (34%), Gaps = 40/298 (13%)

Query: 289 SKLPTPTSSVPAQKTERKESTSGDKPVSH------SCTTPSTSSASGLNPTSAPPTSASA 342
           S  P P  +  A +        G KP++         T P ++  +G   TS PP S   
Sbjct: 32  SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRG 91

Query: 343 VPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSI 402
               P   +   P+           P       L    + IS    V     T+A  +S 
Sbjct: 92  ERAPPAKNTSPGPVSSPGRASGTTRPG-----PLGQKGLRISAEETVARGKATEAPKRSA 146

Query: 403 IH---KFLTAGPSAFNITSLISQAAQL------------STQAQPSNQSPMSLTSDAS-- 445
           +    +  T+GP+    +  +++ ++             S + +P  + P    S AS  
Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206

Query: 446 -----SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVT 500
                SP +   P                S  P+SS P  S P  +  P + +   QP  
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSARGTPRAPAHPSQP-- 263

Query: 501 ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 558
             K +G + + P  +       +P+ GP   S+S  A+ +   P + SA  +    P+
Sbjct: 264 --KPKGLQALRPPQVTPPRKDAAPALGP--LSSSPLATPSPSAPPSPSAPPSLQTLPS 317


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 75/336 (22%), Positives = 130/336 (38%), Gaps = 20/336 (5%)

Query: 237  AETHSSSTPVQHP---------IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGAST 287
            A T S++TP   P           P   PTAT S   SS     +   P  +  A  ++ 
Sbjct: 4264 ASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA 4323

Query: 288  LSKLPTPTSSVPAQKTERKESTSGDKPVS--HSCTTPSTSSASGLNPTSAPPTSASAVPV 345
             S  P P+S++    T  +++T+    +S  H  +TP T+  S +  T A  T A++   
Sbjct: 4324 TSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTS 4383

Query: 346  SPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHK 405
            +P        +L +         A   T   +++      + E+ T A T AS  S    
Sbjct: 4384 TPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGS---- 4439

Query: 406  FLTAGPSAF-NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVP 464
              TA PS+    T ++++ +  +T   P+  +  + ++ A++   +VS   +TP   +  
Sbjct: 4440 --TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK 4497

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
              P  S    ++ P + +        S +A                +  +   S++  S 
Sbjct: 4498 ATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 4557

Query: 525  SPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALA 560
            +P   HTS    A+  T     S A  T S TP  A
Sbjct: 4558 TPETVHTSTVLTATATTTGATGSVA--TPSSTPGTA 4591



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 74/333 (22%), Positives = 132/333 (39%), Gaps = 36/333 (10%)

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES 308
            P  P    TATPS+ P + + L      K +  A   ++     TPTS++      +  +
Sbjct: 1889 PSTPATSSTATPSSTPGTTWIL-----TKPTTTATTTASTGSTATPTSTLRTAPPPKVLT 1943

Query: 309  TSGDKP-VSHSCTTPSTS--SASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 365
            T+   P V+ S  TPS+S  +A+ L    +  T+ +A  V+P+P S +        L + 
Sbjct: 1944 TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTW--TRLSQT 2001

Query: 366  LLPALQATLQLNNSNVDISKINEVLTA----------AVTQASLQSIIH--KFLTAGPSA 413
              P    +    +S  + +  + VLTA            T +S     H  K  T   + 
Sbjct: 2002 TTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTG 2061

Query: 414  FNIT------SLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 467
            F  T      + ++    +ST   P+ +   S  + +S P +  +  + T  T TV    
Sbjct: 2062 FTATPSSSPGTALTPPVWISTTTTPTTRG--STVTPSSIPGTTHTATVLTTTTTTVATGS 2119

Query: 468  LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 527
            + +TP  S+Q   + P +     + +AT          G  P+ P     +++  +P+  
Sbjct: 2120 M-ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPP---VLTTTATTPAAT 2175

Query: 528  PNHTSNSS--NASNATVVPQNSSARSTCSLTPA 558
             N  + SS    ++   VP   +     SL P+
Sbjct: 2176 SNTVTPSSALGTTHTPPVPNTMATTHGRSLPPS 2208



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 83/355 (23%), Positives = 143/355 (40%), Gaps = 62/355 (17%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP-------------TSSVPAQK 302
            PTATPS+ P + + L ++     +  A+  ST +   TP             T +VP   
Sbjct: 4410 PTATPSSTPGTTWIL-TELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGS 4468

Query: 303  TERKEST---SGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS------------AVPVSP 347
            T    ST   +G   VS + TTP+ +S+    P+S+P T+ +            A   + 
Sbjct: 4469 TATASSTQATAGTPHVSTTATTPTVTSSKA-TPSSSPGTATALPALRSTATTPTATSFTA 4527

Query: 348  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQ----------A 397
            +P S +        L +   P    +    +S  +    + VLTA  T           +
Sbjct: 4528 IPSSSLGTTWT--RLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPS 4585

Query: 398  SLQSIIHKF---------LTAGPSAFNITSLISQAAQLSTQAQPSNQSPM---SLTSDAS 445
            S     H            TA PS+   T+L +    +ST   P+  +P    S  + +S
Sbjct: 4586 STPGTAHTTKVPTTTTTGFTATPSSSPGTAL-TPPVWISTTTTPTTTTPTTSGSTVTPSS 4644

Query: 446  SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ 505
             P +  + R+ T  T TV    + +TP  S+Q   + P +     + +AT          
Sbjct: 4645 IPGTTHTARVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP 4703

Query: 506  GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP--QNSSARSTC-SLTP 557
            G  P++P     +S+  +P+   +  ++SS+   AT +P   +++ +ST  S TP
Sbjct: 4704 GTTPITP---VLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTP 4755



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 78/347 (22%), Positives = 128/347 (36%), Gaps = 43/347 (12%)

Query: 242  SSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQ 301
            SS+P      P +  TAT  T  S          P  S      + LS+  TPT+++   
Sbjct: 3216 SSSPGTATALPALRSTATTPTATSVTAI------PSSSL-GTAWTRLSQTTTPTATMSTA 3268

Query: 302  KTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP--------PTSASAVPVSPVPQSPI 353
                   T     V  + TT + ++ S   P+S P        PT+ +    +    SP 
Sbjct: 3269 TPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG 3328

Query: 354  PPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 413
              L     +     P  + +    +S    +    VLT   T  +  S+      A PS+
Sbjct: 3329 TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSM------ATPSS 3382

Query: 414  FNITS-----LISQAAQLSTQAQPSNQS--------PMSLTSDASSPR---SYVSPRIST 457
               TS     L + A  ++     +N S        P  LT+ A++P    S V+P  + 
Sbjct: 3383 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSAL 3442

Query: 458  PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA----TQQPVTADKQQGHEPVSPR 513
              T+T P+    +T    S P  S   V+    S ++    T           H P +  
Sbjct: 3443 GTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATT 3502

Query: 514  SLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS--SARSTCSLTPA 558
            S  + S+    SP P+  +  S  S  T  P ++  ++R+T + TP+
Sbjct: 3503 STTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPS 3549



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 82/365 (22%), Positives = 136/365 (37%), Gaps = 37/365 (10%)

Query: 191  VMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPI 250
            V+  T T+     M    SS  +S  P ++ +  +           + T+ SSTP   PI
Sbjct: 4654 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT-----ITATGSTTNPSSTPGTTPI 4708

Query: 251  KPVVHPTATPSTVPSSPFTLQSDHQ-----PKKSFDANGASTLSKLPTPTS------SVP 299
             PV+  TAT     SS  T  S  +     P  +  A  ++  S  P P+S      +VP
Sbjct: 4709 TPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVP 4768

Query: 300  AQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQD 359
            AQ T    + S      H+ +TP T+  S +  T+A  T A+    +P        +L +
Sbjct: 4769 AQTTTPMSTMS----TIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTE 4824

Query: 360  PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS-AFNITS 418
                     A  +T  L+++      + E  T A       S      T G +    + +
Sbjct: 4825 LTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVT 4884

Query: 419  LISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV-PIKPL------IST 471
             ++     +    PS+ +  +  + A  P S  +  +ST  ++ +  ++P        ST
Sbjct: 4885 TMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFST 4944

Query: 472  PP--------VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRS 523
            P          S    +     + G    +   Q    D+ QG  P SP  +  S+   S
Sbjct: 4945 PCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVS-SAPLSS 5003

Query: 524  PSPGP 528
            PSP P
Sbjct: 5004 PSPAP 5008



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 84/357 (23%), Positives = 135/357 (37%), Gaps = 53/357 (14%)

Query: 239  THSSSTPVQHP----IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            T S +TP   P      P +  TAT  T  S  FT      P  S      + LS+  TP
Sbjct: 3766 TSSKATPFSSPGTATALPALRSTATTPTATS--FTAI----PSSSLGTTW-TRLSQTTTP 3818

Query: 295  TSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTS-ASAVPVSP-----V 348
            T+++          T+    V  +  T + ++ S   P+S P T+  + VP +      V
Sbjct: 3819 TATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTV 3878

Query: 349  PQSPIPPLLQDPN--LLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 406
              S  P   + P   +     P    +    +S    +    VLT   T  +  S+    
Sbjct: 3879 TPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM---- 3934

Query: 407  LTAGPSAFNITS-----LISQAAQLSTQAQPSNQS--------PMSLTSDASSPR---SY 450
              A PS+   TS     LI+ A  ++     +N S        P  LT+ A++P    S 
Sbjct: 3935 --ATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSST 3992

Query: 451  VSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVK-------QGPVSQSATQQPVTADK 503
            V+P  +   T+T P+    +T    S    S   V+        G +  +   +P T   
Sbjct: 3993 VTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS 4052

Query: 504  QQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA--RSTCSLTPA 558
               H P +     + S+    SP P+  +  S  S  T  P +++A  R+T + TP+
Sbjct: 4053 ---HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPS 4106



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 76/355 (21%), Positives = 135/355 (38%), Gaps = 52/355 (14%)

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGA-STLSKLP-----------TPTS 296
            P  P    TATPS+ P + + L        + ++ G+ +T S  P           T T 
Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 3734

Query: 297  SVPAQKT---ERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP------------PTSAS 341
            +VP   T      ++T+G   VS + TTP+ +S S   P S+P             T+ +
Sbjct: 3735 TVPTGSTATASSTQATAGTPHVSTTATTPTVTS-SKATPFSSPGTATALPALRSTATTPT 3793

Query: 342  AVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT---------- 391
            A   + +P S +        L +   P    +    +S  + +  + VLT          
Sbjct: 3794 ATSFTAIPSSSLGTTW--TRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATG 3851

Query: 392  AAVTQASLQSIIH--KFLTAGPSAFNITSLISQAAQ------LSTQAQPSNQSPMSLTSD 443
            +  T +S     H  K  T   + F +T   S          +ST   P+     S  + 
Sbjct: 3852 SVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG--STVTP 3909

Query: 444  ASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADK 503
            +S P +  +P + T  T TV    + +TP  S+Q   + P +     + +AT        
Sbjct: 3910 SSVPGTTHTPTVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLITTATTITATGSTTNPSS 3968

Query: 504  QQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPA 558
              G  P+ P  L  +++  + +      S++   ++   VP  ++     SL+P+
Sbjct: 3969 TPGTTPIPP-VLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPS 4022



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 84/372 (22%), Positives = 137/372 (36%), Gaps = 50/372 (13%)

Query: 237  AETHSSSTPVQH----PIKPVVHPTATPSTVPSSPFTLQSDHQ-----PKKSFDANGAST 287
            A T S++TP       P   V+  TAT  TV SS  T  S        P     A   + 
Sbjct: 1921 ASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 1980

Query: 288  LSKLPTPTSSVPAQKTERKESTSGDKPVSHSC--TTPSTSSASGLNPTSAPPTSASAVPV 345
             S  P P+SS+    T   ++T+    +S +   +TP T+  S +   +A  T A+    
Sbjct: 1981 TSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVA 2040

Query: 346  SP-----------VPQSPIPPLLQDPN------LLRQLLPALQATLQLNNSNVDISKINE 388
            +P           VP +        P+      L   +  +   T     S V  S I  
Sbjct: 2041 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 2100

Query: 389  VLTAAVTQASLQSIIHKFLTAGPSAFNITS-----LISQAAQLSTQAQPSNQS------- 436
                A    +  + +     A PS+   TS     L + A  ++     +N S       
Sbjct: 2101 TTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTP 2160

Query: 437  -PMSLTSDASSPRSY---VSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQ 492
             P  LT+ A++P +    V+P  +   T+T P+   ++T    S P  S   V+    S 
Sbjct: 2161 IPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSA 2220

Query: 493  SA----TQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
            ++    T           H   +     + S+    SP P+  +  S  S  T  P +++
Sbjct: 2221 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTT 2280

Query: 549  A--RSTCSLTPA 558
            A  R+T + TP+
Sbjct: 2281 ATSRTTATATPS 2292



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 74/344 (21%), Positives = 126/344 (36%), Gaps = 44/344 (12%)

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTL----------SKLPTPTSSV 298
            P  P    TATPS+ P + + L        +    G++ +           K+ T T++ 
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034

Query: 299  PAQKTERKESTSGDK-----PVSHSCTTPSTSSA--------SGLNPTSAPPTSASAVPV 345
            P   + +  S+S  +     PV  S  T ST+++         G   T    T+     +
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094

Query: 346  SPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK---INEVLTAAVTQASLQSI 402
            S +  S  P       +L       +AT  ++  +        + E+ TAA T A+    
Sbjct: 3095 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP- 3153

Query: 403  IHKFLTAGPSAF-NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTN 461
                 TA PS+    T ++++ +  +T   P+       T+ ASS R+          T 
Sbjct: 3154 -----TATPSSTPGTTWILTEPSTTATVTVPTGS-----TATASSTRATAGTLKVLTSTA 3203

Query: 462  TVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSS-- 519
            T P   + S    SS P  +T +      + + T   VTA           R  Q ++  
Sbjct: 3204 TTP-TVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3262

Query: 520  ---SQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALA 560
               S  +PS  P     S+  +  T   + + + +T S TP  A
Sbjct: 3263 ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTA 3306



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 71/332 (21%), Positives = 126/332 (37%), Gaps = 51/332 (15%)

Query: 257  TATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVS 316
            TATPS+ P + + L               ST + +  PT S     +   ++T+G   VS
Sbjct: 2455 TATPSSTPGTTWILTE------------PSTTATVTVPTGSTATASS--TQATAGTPHVS 2500

Query: 317  HSCTTPSTSSASGLNPTSAP------------PTSASAVPVSPVPQSPIPPLLQDPNLLR 364
             + TTP+ +S S   P S+P             T+ +A   + +P S +        L +
Sbjct: 2501 TTATTPTVTS-SKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW--TRLSQ 2557

Query: 365  QLLPALQATLQLNNSNVDISKINEVLT----------AAVTQASLQSIIH--KFLTAGPS 412
               P    +    +S  +    + VLT          +  T +S     H  K LT   +
Sbjct: 2558 TTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTT 2617

Query: 413  AFNITSLISQAAQ------LSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIK 466
             F  T   S          +ST   P+ +   S  + +S P +  +P + T  T TV   
Sbjct: 2618 GFTATPSSSPGTARTLPVWISTTTTPTTRG--STVTPSSIPGTTHTPTVLTTTTTTVATG 2675

Query: 467  PLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSP 526
             + +TP  S+Q   + P +     + +AT          G  P+ P  L  +++  + + 
Sbjct: 2676 SM-ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPP-VLTTTATTPAATS 2733

Query: 527  GPNHTSNSSNASNATVVPQNSSARSTCSLTPA 558
                 S++   ++   VP  ++     SL+P+
Sbjct: 2734 STVTPSSALGTTHTPPVPNTTATTHGRSLSPS 2765



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 83/399 (20%), Positives = 149/399 (37%), Gaps = 43/399 (10%)

Query: 196  ATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH 255
            AT+   +G     SS   +  P  +L+ T+           ++  SSS+P      PV+ 
Sbjct: 3003 ATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT----SSKATSSSSPRTATTLPVLT 3058

Query: 256  PTATPST----VPSSPFTLQSDHQPKKSFDANGA--STLSKLPTP-TSSVPAQKTERKES 308
             TAT ST     P   FTL +     +      A  ST+    TP T+      T +  +
Sbjct: 3059 STATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATT 3118

Query: 309  TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 368
            T     +S   +TP T+       T+A  T+A+    +P        +L +P+    +  
Sbjct: 3119 TRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTV 3178

Query: 369  ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG--------------PSAF 414
               +T   +++      +  + + A T   + S      + G              P+A 
Sbjct: 3179 PTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTAT 3238

Query: 415  NITSLISQA-----AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI 469
            ++T++ S +      +LS    P+  + MS  + +S+P +  +  + T  T T      +
Sbjct: 3239 SVTAIPSSSLGTAWTRLSQTTTPT--ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSV 3296

Query: 470  STPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPV-----SPRSLQRSSSQRSP 524
            +TP  SS P  +         +   T  P ++       PV     +  + + S+   S 
Sbjct: 3297 ATP--SSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSS 3354

Query: 525  SPGPNHTSNSSNASNATVVPQN----SSARSTCSLTPAL 559
             PG  HT+     +  TV   +    SS+  T    P+L
Sbjct: 3355 IPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSL 3393



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 80/357 (22%), Positives = 129/357 (36%), Gaps = 53/357 (14%)

Query: 239  THSSSTPVQHP----IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            T S +TP   P      P +  TAT  T  S  FT      P  S      + LS+  TP
Sbjct: 2509 TSSKATPFSSPGTATALPALRSTATTPTATS--FTAI----PSSSLGTTW-TRLSQTTTP 2561

Query: 295  TSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 354
            T+++          T     V  +  T + ++ S   P+S P T+ +   ++        
Sbjct: 2562 TATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTA 2621

Query: 355  PLLQDPNLLRQL--------LPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKF 406
                 P   R L         P  + +    +S    +    VLT   T  +  S+    
Sbjct: 2622 TPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM---- 2677

Query: 407  LTAGPSAFNITS-----LISQAAQLSTQAQPSNQS--------PMSLTSDASSPR---SY 450
              A PS+   TS     L + A  ++     +N S        P  LT+ A++P    S 
Sbjct: 2678 --ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSST 2735

Query: 451  VSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVK-------QGPVSQSATQQPVTADK 503
            V+P  +   T+T P+    +T    S    S   V+        G +  +   +P T   
Sbjct: 2736 VTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS 2795

Query: 504  QQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA--RSTCSLTPA 558
               H P +     + S+    SP P+  +  S  S  T  P ++ A  R+T + TP+
Sbjct: 2796 ---HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPS 2849



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 73/300 (24%), Positives = 112/300 (37%), Gaps = 45/300 (15%)

Query: 257  TATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVS 316
            T TPS++P +  T                +T + + T + + P+  T+    TSG  P  
Sbjct: 3349 TVTPSSIPGTTHTATVL-----------TTTTTTVATGSMATPSSSTQ----TSGTPPSL 3393

Query: 317  HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQL 376
             +  T  T++ S  NP+S P T            +PIPP+L          PA  ++   
Sbjct: 3394 TTTATTITATGSTTNPSSTPGT------------TPIPPVL----TTTATTPAATSSTVT 3437

Query: 377  NNSNVDISKINEV--LTAAVTQASL-QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS 433
             +S +  +    V   TA     SL  S  H   TA  SA   TS I     ++  +  +
Sbjct: 3438 PSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSA---TSGILGTTHITEPSTVT 3494

Query: 434  NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP----PVSSQPKVSTPVVKQGP 489
            + +P + TS        +S    + +T   P  P  +TP      S     +TP   +  
Sbjct: 3495 SHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTS 3554

Query: 490  --VSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTSNSSNASNATVVPQ 545
              +  S T  P+T     G EP    S  L  S     PS G   T ++  A+   V  Q
Sbjct: 3555 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 3614



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 49/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)

Query: 191  VMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPI 250
            V+  T T+     M    SS  +S  P ++ +  +           + T+ SSTP   PI
Sbjct: 3364 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT-----ITATGSTTNPSSTPGTTPI 3418

Query: 251  KPVVHPTATPSTVPSSPFT----LQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERK 306
             PV+  TAT     SS  T    L + H P      N  +T      P SS    +T   
Sbjct: 3419 PPVLTTTATTPAATSSTVTPSSALGTTHTPPV---PNTTATTHGRSLPPSSPHTVRTAWT 3475

Query: 307  ESTSGDKPVSH----SCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNL 362
             +TSG    +H    S  T  T +A+      + P  +S  P S   +SP  P    P  
Sbjct: 3476 SATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 3535

Query: 363  LR 364
             R
Sbjct: 3536 TR 3537



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 49/198 (24%), Positives = 73/198 (36%), Gaps = 17/198 (8%)

Query: 160  PKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQN 219
            P  W+        +      S      +   V+  T T+     M    SS  +S  P +
Sbjct: 3890 PPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPS 3949

Query: 220  ILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFT----LQSDHQ 275
            +++  +           + T+ SSTP   PI PV+  TAT     SS  T    L + H 
Sbjct: 3950 LITTATT-----ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 4004

Query: 276  PKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSA 335
            P      N  +T        SS    +T    +TSG    +H  T PST ++    P + 
Sbjct: 4005 PPV---PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH-ITEPSTGTSH--TPAAT 4058

Query: 336  PPTSASAVPV--SPVPQS 351
              T+  + P   SP P S
Sbjct: 4059 TGTTQHSTPALSSPHPSS 4076



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 16/182 (8%)

Query: 191  VMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPI 250
            V+  T T+     M    SS  +S  P ++ +  +           + T+ SSTP   PI
Sbjct: 2664 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT-----ITATGSTTNPSSTPGTTPI 2718

Query: 251  KPVVHPTATPSTVPSSPFT----LQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERK 306
             PV+  TAT     SS  T    L + H P      N  +T        SS    +T   
Sbjct: 2719 PPVLTTTATTPAATSSTVTPSSALGTTHTPPV---PNTTATTHGRSLSPSSPHTVRTAWT 2775

Query: 307  ESTSGDKPVSH----SCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNL 362
             +TSG    +H    S  T  T +A+      + P  +S  P S   +SP  P    P  
Sbjct: 2776 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 2835

Query: 363  LR 364
             R
Sbjct: 2836 TR 2837



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 53/204 (25%)

Query: 191  VMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPI 250
            V+  T T+     M    SS  +S  P ++ +  +           + T+ SSTP   PI
Sbjct: 2107 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT-----ITATGSTTNPSSTPGTTPI 2161

Query: 251  KPVVHPTAT-----------------------PSTV---------PSSPFTLQSDHQPKK 278
             PV+  TAT                       P+T+         PSSP T+++      
Sbjct: 2162 PPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSAT 2221

Query: 279  SFDANGASTLSKLPTPTS------------SVPAQKTERKESTSGDKPVSHSCTTPSTSS 326
            S    G + +++  T TS            S PA  +    S + + P S   TTP  ++
Sbjct: 2222 S-GILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTT 2280

Query: 327  ASGLNPTSAPPT---SASAVPVSP 347
            A+     +A P+   +++ +P SP
Sbjct: 2281 ATSRTTATATPSKTRTSTLLPSSP 2304



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 313  KPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP-QSPIPP 355
            K ++ +   P +       PT  PPT++ A PVS  P  +P PP
Sbjct: 5247 KDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP 5290


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 86/372 (23%), Positives = 140/372 (37%), Gaps = 45/372 (12%)

Query: 194  ATATSGFASGMEDKHSS-DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKP 252
            ++ TSG +      HSS DAS   P +  S TS   +         T S  +P    I  
Sbjct: 3819 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE--------STTSRISPGSTEITT 3870

Query: 253  VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
            +   T TP    +S     S   P         +TLS     +  V  + T     TS  
Sbjct: 3871 LPGSTTTPGLSEASTTFYSSPRSP--------TTTLSPASMTSLGVGEEST-----TSRS 3917

Query: 313  KPVS-HSCTTPSTSSASGLNPTSAPPTSAS--AVPVSPVPQSPIPPLLQDPNLLRQLLPA 369
            +P S HS  +P++++  GL+  S    S+S  +   +  P+S    + ++        PA
Sbjct: 3918 QPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPA 3977

Query: 370  LQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQ 429
               T      +       E      + AS Q+ +   LT        T+  S +    T+
Sbjct: 3978 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK 4037

Query: 430  AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGP 489
              P+  +   L  +++  R  +SP  S+ +T T+P  P  +TP +S +    +      P
Sbjct: 4038 LSPARSTTSGLVGESTPSR--LSP--SSTETTTLPGSP--TTPSLSEK----STTFYTSP 4087

Query: 490  VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTS----------NSSNASN 539
             S  AT  P T       E  S    Q  S+  +  P    TS          +S  ++ 
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTE 4147

Query: 540  ATVVPQNSSARS 551
            AT+ P +++A S
Sbjct: 4148 ATLSPGSTTASS 4159



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 126/574 (21%), Positives = 206/574 (35%), Gaps = 115/574 (20%)

Query: 64   SPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSAL--HSSNSHSSNPSNN- 120
            SP    S ++  S   +  +   R R G T  +   +S     L  HS+ SHSS  S + 
Sbjct: 975  SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 1034

Query: 121  ----PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKM 176
                 S T+  P  S +  + H SSSG     +  T +S          +E     +N  
Sbjct: 1035 TLLPASTTTSGP--SQESTTSH-SSSG-----STDTALSPGSTTALSFGQESTTFHSNPG 1086

Query: 177  AVNS--FPKDRDYRREVMQATATSGFASGMEDKHSSDAS---SLLPQNILSQTSRHNDRD 231
            + ++  FP           +T +SG        HSS  S   +L P +  S   +     
Sbjct: 1087 STHTTLFP----------DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 1136

Query: 232  YRLPRAETHSSSTPVQHPIKPVVHPTA---TPSTVPSSPF---TLQSDHQPKKSF----- 280
            ++   A TH++ +P      PV   T    +P + P++ F   +  S H  K +      
Sbjct: 1137 FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 1196

Query: 281  DANGA--------------STLSKL--------------------------------PTP 294
            DA+G               ST S++                                PT 
Sbjct: 1197 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256

Query: 295  TSSVPAQKTE----RKESTSGDKPVS-HSCTTPSTSSASGLNPTSAPPTSAS--AVPVSP 347
            T S PA  T      + +TS  +P S HS  +P++++  GL+  S    S+S  +   + 
Sbjct: 1257 TLS-PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV 1315

Query: 348  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 407
             P S    +  +        PA   T      +       E      + AS Q+ +   L
Sbjct: 1316 FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 1375

Query: 408  TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 467
            T        T+  S +    T+  P+  +   L  +++  R  +SP  S+ +T T+P  P
Sbjct: 1376 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR--LSP--SSTETTTLPGSP 1431

Query: 468  LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 527
              +TP +S +    +      P S  AT  P T       E  S    Q  S+  +  P 
Sbjct: 1432 --TTPSLSEK----STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD 1485

Query: 528  PNHTS----------NSSNASNATVVPQNSSARS 551
               TS          +S  ++ AT+ P +++A S
Sbjct: 1486 STTTSDLSQEPTTSHSSQGSTEATLSPGSTTASS 1519



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 85/369 (23%), Positives = 135/369 (36%), Gaps = 38/369 (10%)

Query: 194  ATATSGFASGMEDKHSS-DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKP 252
            ++ TSG +      HSS DAS   P +  S TS   +         T S  +P    I  
Sbjct: 2262 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE--------STTSRISPGSTEITT 2313

Query: 253  VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
            +   T TP    +S     S   P         +TLS     +  V  + T     TS  
Sbjct: 2314 LPGSTTTPGLSEASTTFYSSPRSP--------TTTLSPASMTSLGVGEEST-----TSRS 2360

Query: 313  KPVS-HSCTTPSTSSASGLNPTSAPPTSAS--AVPVSPVPQSPIPPLLQDPNLLRQLLPA 369
            +P S HS  +P++++  GL+  S    S+S  +   +  P++P   +  +        PA
Sbjct: 2361 QPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPA 2420

Query: 370  LQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQ 429
               T      +       E      + AS Q+ +   LT        T+  S +    T 
Sbjct: 2421 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT 2480

Query: 430  AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGP 489
              P+  +   L  +++  R  +SP  S+ +T T+P  P  +TP +S +    +      P
Sbjct: 2481 LSPARSTTSGLVGESTPSR--LSP--SSTETTTLPGSP--TTPSLSEK----STTFYTSP 2530

Query: 490  VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA 549
             S  AT  P T       E  S    Q  S+  +  P    T   S  S  +    +S  
Sbjct: 2531 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTS---HSSPG 2587

Query: 550  RSTCSLTPA 558
             +  +L PA
Sbjct: 2588 STDTTLLPA 2596



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 124/573 (21%), Positives = 205/573 (35%), Gaps = 115/573 (20%)

Query: 52   PSPPNKMLRRSDSPENKYSD--STGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHS 109
            P  P+  L  + +  +  S+  ST HS+  + HT         T++ P   +    + HS
Sbjct: 2530 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT---------TAF-PDSTTTPGLSRHS 2579

Query: 110  SNSHSSNPSNNP-----SKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWL 164
            + SHSS  S +      S T+  P  S +  + H SS G     +  T +S         
Sbjct: 2580 TTSHSSPGSTDTTLLPASTTTSGP--SQESTTSH-SSPG-----STDTALSPGSTTALSF 2631

Query: 165  EREQRQKEANKMAVNS--FPKDRDYRREVMQATATSGFASGMEDKHSSDAS---SLLPQN 219
             +E     ++  + ++  FP           +T +SG        HSS  S   +L P +
Sbjct: 2632 GQESTTFHSSPGSTHTTLFP----------DSTTSSGIVEASTRVHSSTGSPRTTLSPAS 2681

Query: 220  ILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTA---TPSTVPSSPF---TLQSD 273
              S   +     ++   A TH++ +P      PV   T    +P + P++ F   +  S 
Sbjct: 2682 STSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG 2741

Query: 274  HQPKKSF-----DANGA--------------STLSKL----------------------- 291
            H  K +      DA+G               ST S++                       
Sbjct: 2742 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS 2801

Query: 292  ---------PTPTSSVPAQKTE----RKESTSGDKPVS-HSCTTPSTSSASGLNPTSAPP 337
                     PT T S PA  T      + +TS  +P S HS  +P++++  GL+  S   
Sbjct: 2802 TTFYSSPRSPTTTLS-PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTV 2860

Query: 338  TSAS--AVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVT 395
             S+S  +   +  P+S    +  +        PA   T      +       E      +
Sbjct: 2861 YSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 2920

Query: 396  QASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRI 455
             AS Q+ +   LT        T+  S +    T   P+  +   L  +++  R  +SP  
Sbjct: 2921 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSR--LSP-- 2976

Query: 456  STPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSL 515
            S+ +T T+P  P  +TP +S +    +      P S  AT  P T       E  S    
Sbjct: 2977 SSTETTTLPGSP--TTPSLSEK----STTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 3030

Query: 516  QRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
            Q  S+  +  P    TS  S    A+   Q S+
Sbjct: 3031 QPGSTHTTAFPDSTTTSGLSQEPTASHSSQGST 3063



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 80/354 (22%), Positives = 130/354 (36%), Gaps = 48/354 (13%)

Query: 242  SSTPVQH--PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVP 299
            SSTP  H       +  +   +TV SSP    +   P +S  +      +   +   S  
Sbjct: 3421 SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQ 3480

Query: 300  AQKTERKESTSG---DKPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSPVPQ 350
                   ++TSG   +   SHS TT      PST+SA    PTS   +S  +   +  P 
Sbjct: 3481 TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY-HSSPGSTATTHFPD 3539

Query: 351  SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG 410
            S       + +           T+ L   +     + E  T+ ++  S+++      TA 
Sbjct: 3540 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET------TAL 3593

Query: 411  PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST------------- 457
            P +     L    ++ ST    S +SP +  S AS+  S VS   +T             
Sbjct: 3594 PGSTTTPGL----SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 3649

Query: 458  PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGH-----EPVSP 512
            P + T P     ST   SS     T ++     +  ++Q+  T+    G       P S 
Sbjct: 3650 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGST 3709

Query: 513  RSLQ--RSSSQRSPSPGPNHT------SNSSNASNATVVPQNSSARSTCSLTPA 558
             +L   + S+    SPG  HT      + SS    A+    +S+     +L+PA
Sbjct: 3710 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 3763



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 86/398 (21%), Positives = 140/398 (35%), Gaps = 47/398 (11%)

Query: 195  TATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRD--YRLPRAETHSSSTPVQHPIKP 252
            T  SG        HSS  S     +    T+R  +    +  P ++    + P       
Sbjct: 739  TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTT--TSA 796

Query: 253  VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
             V P+ T    PSS  T     +   S     ++T    P  T ++   +++       +
Sbjct: 797  FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856

Query: 313  KPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQL 366
               SHS TT      PST+SA    PTS   +S  +   +  P S       + +     
Sbjct: 857  STTSHSSTTHTISSAPSTTSALVEEPTSY-HSSPGSTATTHFPDSSTTSGRSEESTASHS 915

Query: 367  LPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQL 426
                  T+ L   +     + E  T+ ++  S+++      TA P +     L    ++ 
Sbjct: 916  SQDATGTIVLPARSTTSVLLGESTTSPISSGSMET------TALPGSTTTPGL----SER 965

Query: 427  STQAQPSNQSPMSLTSDASSPRSYVSPRIST-------------PQTNTVPIKPLISTPP 473
            ST    S +SP +  S AS+  S VS   +T             P + T P     ST  
Sbjct: 966  STTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTS 1025

Query: 474  VSSQPKVSTPVV-----KQGPVSQSATQQPVTADKQQGHEPVSPRSLQ--RSSSQRSPSP 526
             SS     T ++       GP  +S T    +        P S  +L   + S+    +P
Sbjct: 1026 HSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNP 1085

Query: 527  GPNHT------SNSSNASNATVVPQNSSARSTCSLTPA 558
            G  HT      + SS    A+    +S+     +L+PA
Sbjct: 1086 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 77/331 (23%), Positives = 126/331 (38%), Gaps = 31/331 (9%)

Query: 240  HSSSTPVQHPIKPVVH--PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP-TPTS 296
            HS++T V        H  P +T +T+ +   T     +   +F  + AST + LP T T+
Sbjct: 1318 HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 1377

Query: 297  SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT-SASAVPVSPVPQSPIPP 355
            +   +++    S+SG      S   P+ S+ SGL   S P   S S+   + +P SP  P
Sbjct: 1378 ADLGEESTTFPSSSGSTGTKLS---PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 1434

Query: 356  LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
             L + +           T   +  + D +     L+ A T +S  S       + P + +
Sbjct: 1435 SLSEKS----------TTFYTSPRSPDAT-----LSPATTTSSGVSEESSTSHSQPGSTH 1479

Query: 416  ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVS 475
             T+        ST     +Q P +  S   S  + +SP  +T  +         S+P  +
Sbjct: 1480 TTAFPD-----STTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 1534

Query: 476  SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTSN 533
                +    +  G V  S      T        P S  S  LQ  S+     P  + T+ 
Sbjct: 1535 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 1594

Query: 534  SSNASNATVVPQNSSARSTCSLTPALAAHFS 564
            S   + A  V  +++  S  S TP    HFS
Sbjct: 1595 SPPGTTAAPVEVSTTYHSRPSSTP--TTHFS 1623



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 69/324 (21%), Positives = 129/324 (39%), Gaps = 23/324 (7%)

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV 315
            P++TP+T  S+  T     +   +  ++  +T +  P+P  S  +   E   +       
Sbjct: 4503 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT-PSPARSTTSGLVEESTTYHSSPGS 4561

Query: 316  SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQ 375
            + +   P +++ SG    S    S++   +S  P S    L+++P       P   AT  
Sbjct: 4562 TQTMHFPESNTTSGRGEESTTSHSSTTHTISSAP-STTSALVEEPTSYHSS-PGSTATTH 4619

Query: 376  LNNSNVDISKINEVLTAAVTQASLQSII--HKFLTAGPSAFNITSLISQAAQLSTQAQPS 433
              +S+    +  E   +  +Q +  +I+   +  T+     + TS IS  +  +T    S
Sbjct: 4620 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 4679

Query: 434  NQSP----MSLT---SDASSPRSYVSPRIST----PQTNTVPIKPLISTPPVSSQPKVST 482
              +P     S T   S +S+P ++ S   +T     ++ TV   P ++T    S  + +T
Sbjct: 4680 TTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSP-VATATTPSPARSTT 4738

Query: 483  PVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATV 542
                 G V +S          Q  H P S  +  RS   R+      HT +S  ++ + +
Sbjct: 4739 ----SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 4794

Query: 543  VPQNSSARSTCSLTPALAAHFSEN 566
            V + +S  S  S       HF E+
Sbjct: 4795 VEEPTSYHS--SPGSIATTHFPES 4816



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 76/330 (23%), Positives = 127/330 (38%), Gaps = 31/330 (9%)

Query: 241  SSSTPVQHPIKPVVH--PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP-TPTSS 297
            S++T V+       H  P +T +T+ +   T     +   +F  + AST + LP T T++
Sbjct: 3959 STTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 4018

Query: 298  VPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT-SASAVPVSPVPQSPIPPL 356
               +++    S+SG      S   P+ S+ SGL   S P   S S+   + +P SP  P 
Sbjct: 4019 DLGEESTTFPSSSGSTGTKLS---PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 4075

Query: 357  LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNI 416
            L + +           T   +  + D +     L+ A T +S  S       + P + + 
Sbjct: 4076 LSEKS----------TTFYTSPRSPDAT-----LSPATTTSSGVSEESSTSHSQPGSTHT 4120

Query: 417  TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476
            T+        ST     +Q P +  S   S  + +SP  +T  +         S+P  + 
Sbjct: 4121 TAFPD-----STTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTE 4175

Query: 477  QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTSNS 534
               +    +  G V  S      T        P S  S  LQ  S+     P  + T+ S
Sbjct: 4176 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPS 4235

Query: 535  SNASNATVVPQNSSARSTCSLTPALAAHFS 564
              ++ A  V  +++  S  S TP    HFS
Sbjct: 4236 PPSTTAVPVEVSTTYHSRPSSTP--TTHFS 4263



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 70/331 (21%), Positives = 122/331 (36%), Gaps = 31/331 (9%)

Query: 261  STVPSSPFTLQSDHQPKKSFDAN--GASTLSKLP---TPTSSVPAQKT----ERKESTSG 311
            +T PSS  +  +   P +S  +   G ST S+L    T T+++P   T      K +T  
Sbjct: 2468 TTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY 2527

Query: 312  DKPVSHSCT-TPSTSSASGLNPTSAPPTSA-SAVPVSPVPQSPIPPLLQDPNLLRQLLPA 369
              P S   T +P+T+++SG++  S+   S   +   +  P S   P L   +      P 
Sbjct: 2528 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 2587

Query: 370  LQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS----------------- 412
               T  L  S        E  T+  +  S  + +    T   S                 
Sbjct: 2588 STDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHT 2647

Query: 413  -AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIST 471
              F  ++  S   + ST+   S  SP +  S ASS    +    +T QT+        S 
Sbjct: 2648 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSP 2707

Query: 472  PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 531
            P  ++ P   +    + P S   T  P ++      E  +       +S  +PS   + T
Sbjct: 2708 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 2767

Query: 532  SNSSNASNATVVPQNSSARST--CSLTPALA 560
            S    ++ + + P ++   +    + TP L+
Sbjct: 2768 SGRGESTTSRISPGSTEITTLPGSTTTPGLS 2798



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 77/334 (23%), Positives = 128/334 (38%), Gaps = 31/334 (9%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP-T 293
            PR+ T  +S   + P      P +T +T+ +   T     +   +F  + AST + LP T
Sbjct: 2874 PRSTT--TSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT 2931

Query: 294  PTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT-SASAVPVSPVPQSP 352
             T++   +++    S+SG    + S   P+ S+ SGL   S P   S S+   + +P SP
Sbjct: 2932 LTTADLGEESTTFPSSSGSTGTTLS---PARSTTSGLVGESTPSRLSPSSTETTTLPGSP 2988

Query: 353  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 412
              P L + +           T   +  + D +     L+ A T +S  S       + P 
Sbjct: 2989 TTPSLSEKS----------TTFYTSPRSPDAT-----LSPATTTSSGVSEESSTSHSQPG 3033

Query: 413  AFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP 472
            + + T+        ST     +Q P +  S   S  + +SP  +T  +         S+P
Sbjct: 3034 STHTTAFPD-----STTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 3088

Query: 473  PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNH 530
              +    +    +  G V  S      T        P S  S  LQ  S+     P  + 
Sbjct: 3089 GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD 3148

Query: 531  TSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 564
            T+ S   + A  V  +++  S  S TP    HFS
Sbjct: 3149 TTPSPPGTTAAPVEVSTTYHSRPSSTP--TTHFS 3180



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 110/545 (20%), Positives = 180/545 (33%), Gaps = 92/545 (16%)

Query: 14   GCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDST 73
            G   R+G+S  +        S PSS D R         P+PP       +        +T
Sbjct: 766  GSTTRQGESTTFH-------SWPSSKDTR---------PAPPTTTSAFVEP------STT 803

Query: 74   GHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSAD 133
             H    ++ T  +  R   TS   +E++  HS+  S+ +     S+  S   +    S  
Sbjct: 804  SHGSPSSIPTTHISARST-TSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 862

Query: 134  DWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQ 193
              +  ISS+         T  +  E+P  +             A   FP           
Sbjct: 863  STTHTISSAPS-------TTSALVEEPTSY------HSSPGSTATTHFP----------D 899

Query: 194  ATATSGFASGMEDKHSS-DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKP 252
            ++ TSG +      HSS DA+  +     S TS         P +     +T +      
Sbjct: 900  SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS--- 956

Query: 253  VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
                T TP     S     S   P        A+TLS   T +S V  + T  +      
Sbjct: 957  ----TTTPGLSERSTTFHSSPRSP--------ATTLSPASTTSSGVSEESTTSRSRPGST 1004

Query: 313  KPVSH--SCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 370
               +   S TTP  S  S  + +S   T  + +P S     P                + 
Sbjct: 1005 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP----------------SQ 1048

Query: 371  QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL-TAGPSAFNITSLISQAAQLSTQ 429
            ++T   ++S    + ++   T A++     +  H    +   + F  ++  S   + ST+
Sbjct: 1049 ESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTR 1108

Query: 430  AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGP 489
               S  SP +  S ASS     SP +    T          T P S+    S P     P
Sbjct: 1109 VHSSTGSPRTTLSPASS----TSPGLQGEST-------AFQTHPASTHTTPSPPSTATAP 1157

Query: 490  VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA 549
            V +S T           H P S  +   S         P+ +  + +++++T   +  S 
Sbjct: 1158 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 1217

Query: 550  RSTCS 554
             S  S
Sbjct: 1218 TSRIS 1222



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 81/370 (21%), Positives = 125/370 (33%), Gaps = 47/370 (12%)

Query: 194  ATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPV 253
            +TAT+ F        SS  S    ++  S +S+       LP   T +S    +    P+
Sbjct: 1974 STATTHFPD------SSTTSGRSEESTASHSSQDATGTIVLPARST-TSVLLGESTTSPI 2026

Query: 254  VHPTATPSTVPSSPFT--LQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
               +   + +P S  T  L        S   + A+TLS   T +S V  + T     TS 
Sbjct: 2027 SSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST-----TSH 2081

Query: 312  DKPVS-------HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLR 364
             +P S        S TTP  S  S  + +S   T  + +P S     P        +   
Sbjct: 2082 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP-----SQESTTS 2136

Query: 365  QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAA 424
               P    T     S   +S   E  T   +  S  + +          F  ++  S   
Sbjct: 2137 HSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL----------FPDSTTSSGIV 2186

Query: 425  QLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPV 484
            + ST+   S  SP +  S ASS     SP +    T          T P S+    S P 
Sbjct: 2187 EASTRVHSSTGSPRTTLSPASS----TSPGLQGEST-------AFQTHPASTHTTPSPPS 2235

Query: 485  VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP 544
                PV +S T           H P S  +   S         P+ +  + +++++T   
Sbjct: 2236 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 2295

Query: 545  QNSSARSTCS 554
            +  S  S  S
Sbjct: 2296 RGESTTSRIS 2305



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 78/371 (21%), Positives = 130/371 (35%), Gaps = 49/371 (13%)

Query: 194  ATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPV 253
            +TAT+ F        SS  S    ++  S +S+       LP   T +S    +    P+
Sbjct: 3531 STATTHFPD------SSTTSGRSEESTASHSSQDATGTIVLPARST-TSVLLGESTTSPI 3583

Query: 254  VHPTATPSTVPSSPFT--LQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
               +   + +P S  T  L        S   + A+TLS   T +S V  + T     TS 
Sbjct: 3584 SSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST-----TSH 3638

Query: 312  DKPVS-------HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLR 364
             +P S        S TTP  S  S  + +S   T  + +P S                  
Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS------------ 3686

Query: 365  QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL-TAGPSAFNITSLISQA 423
                + ++T   ++S    + ++   T A++     +  H    +   + F  ++  S  
Sbjct: 3687 ----SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 3742

Query: 424  AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTP 483
             + ST+   S  SP +  S ASS     SP +    T          T P S+    S P
Sbjct: 3743 VEASTRVHSSTGSPRTTLSPASS----TSPGLQGEST-------AFQTHPASTHTTPSPP 3791

Query: 484  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV 543
                 PV +S T           H P S  +   S         P+ +  + +++++T  
Sbjct: 3792 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 3851

Query: 544  PQNSSARSTCS 554
             +  S  S  S
Sbjct: 3852 GRGESTTSRIS 3862



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 83/387 (21%), Positives = 151/387 (39%), Gaps = 75/387 (19%)

Query: 194  ATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPV 253
            +T T G +      HSS +S+       S T+        L R+E   S+T    P+   
Sbjct: 4679 STTTPGLSEKSTTFHSSPSSTPTTHFSASSTT--------LGRSE--ESTTVHSSPVATA 4728

Query: 254  VHPTATPSTVP----------SSPFTLQSDHQPKKSFDANGAS------------TLSKL 291
              P+   ST            SSP + Q+ H P+ S  A+G S            T+S  
Sbjct: 4729 TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESS-TASGRSEESRTSHSSTTHTISSP 4787

Query: 292  PTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTS-APPTSASAVPVSPVPQ 350
            P+ TS++  + T    S+ G    +H    P +S+ SG +  S A  +S     ++P+P 
Sbjct: 4788 PSTTSALVEEPTSY-HSSPGSIATTHF---PESSTTSGRSEESTASHSSPDTNGITPLPA 4843

Query: 351  SPIPPLLQDPNLLRQLLP-ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTA 409
                      +    + P +++ TL    +   +S  + +L ++ +++  Q++    +T+
Sbjct: 4844 HFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSS-SRSPDQTLSPASMTS 4902

Query: 410  GPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLI 469
               +   TSL SQA    T A P++ +   L+ ++++                       
Sbjct: 4903 SSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTT----------------------- 4939

Query: 470  STPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ---GHEPVSPRS-----LQRSSSQ 521
                  S+P  +   +  G ++ S+  Q  T    Q       VSP S     L   S+ 
Sbjct: 4940 ----FHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTT 4995

Query: 522  RSPSPGPNHTSNSSNASNATVVPQNSS 548
               SPG   T+  S+++  ++  Q S+
Sbjct: 4996 FYSSPGSTETTAFSHSNTMSIHSQQST 5022



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 106/503 (21%), Positives = 168/503 (33%), Gaps = 86/503 (17%)

Query: 75   HSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADD 134
            HS   ++HT         TS   QE S    +  SS    S+ + +P  T+ AP + +  
Sbjct: 1556 HSSTGSLHTTLTPA--SSTSAGLQEESTTFQSWPSS----SDTTPSPPGTTAAPVEVSTT 1609

Query: 135  WSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQA 194
            +    SS+   ++    T + + E      E               FP  R     ++  
Sbjct: 1610 YHSRPSSTPTTHFSASSTTLGRSE------ESTTVHSSPGATGTALFPT-RSATSVLVGE 1662

Query: 195  TATSGFASGMEDKHSSDASSL---LPQNILSQTSRHNDRDYRLPRAETHSSS----TPVQ 247
              TS  +SG  +  +   S+    L +   +  S     D  L  A T SS     +   
Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1722

Query: 248  HPIKPVVHPTATP--STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTER 305
            H      H TA P  +T+P       + H    S D    +TLS   T  SS+  + T  
Sbjct: 1723 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD----TTLSPGSTTASSLGPESTTF 1778

Query: 306  KESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 365
              S       + +   P  ++ASGL   S P  S++         SP   L    +  RQ
Sbjct: 1779 HSSPGS----TETTLLPDNTTASGLLEASTPVHSSTG--------SPHTTLSPAGSTTRQ 1826

Query: 366  LLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQ 425
                   T Q   S+ D        T+A  + S  S         PS+   T   + +  
Sbjct: 1827 ---GESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS------HGSPSSTPTTHFSASSTT 1877

Query: 426  L--STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTP 483
            L  S ++   + SP++  +  S  RS  S                               
Sbjct: 1878 LGRSEESTTVHSSPVATATTPSPARSTTS------------------------------- 1906

Query: 484  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV 543
                G V +S          Q  H P S  +  RS   R+      HT +S  ++ + +V
Sbjct: 1907 ----GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1962

Query: 544  PQNSSARSTCSLTPALAAHFSEN 566
             + +S  S+   T     HF ++
Sbjct: 1963 EEPTSYHSSPGST--ATTHFPDS 1983



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 107/502 (21%), Positives = 169/502 (33%), Gaps = 84/502 (16%)

Query: 75   HSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADD 134
            HS   ++HT         TS   QE S    +  SS    S+ + +P  T+ AP + +  
Sbjct: 3113 HSSTGSLHTTLTPA--SSTSAGLQEESTTFQSWPSS----SDTTPSPPGTTAAPVEVSTT 3166

Query: 135  WSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQA 194
            +    SS+   ++    T + + E      E               FP  R     ++  
Sbjct: 3167 YHSRPSSTPTTHFSASSTTLGRSE------ESTTVHSSPGATGTALFPT-RSATSVLVGE 3219

Query: 195  TATSGFASGMEDKHSSDASSL---LPQNILSQTSRHNDRDYRLPRAETHSSS----TPVQ 247
              TS  +SG  +  +   S+    L +   +  S     D  L  A T SS     +   
Sbjct: 3220 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 3279

Query: 248  HPIKPVVHPTATP--STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTER 305
            H      H TA P  +T+P       + H    S D    +TLS   T  SS+  + T  
Sbjct: 3280 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD----TTLSPGSTTASSLGPEST-- 3333

Query: 306  KESTSGDKPVSHSCTT-PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLR 364
               T    P S   T  P  ++ASGL   S P  S++  P +                  
Sbjct: 3334 ---TFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT----------------- 3373

Query: 365  QLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAA 424
             L PA   T Q  ++       ++  T A    +             SAF   S  S  +
Sbjct: 3374 -LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTT-------------SAFVELSTTSHGS 3419

Query: 425  QLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPV 484
              ST     + S  +L     S   + SP               ++T    S  + +T  
Sbjct: 3420 PSSTPTTHFSASSTTLGRSEESTTVHSSP---------------VATATTPSPARSTT-- 3462

Query: 485  VKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVP 544
               G V +S T        Q  H P S  +  R     +      HT +S+ ++ + +V 
Sbjct: 3463 --SGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE 3520

Query: 545  QNSSARSTCSLTPALAAHFSEN 566
            + +S  S+   T     HF ++
Sbjct: 3521 EPTSYHSSPGST--ATTHFPDS 3540



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 74/318 (23%), Positives = 121/318 (38%), Gaps = 48/318 (15%)

Query: 258 ATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSH 317
           +TPS+  S PFT  SD+    +F     +T   L + T+S            S +  VSH
Sbjct: 181 STPSS--SDPFTTFSDYGVSVTFITGSTATKHFLDSSTNS----------GHSEESTVSH 228

Query: 318 SCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLN 377
                  S       T  P  SA++V V     SPI       ++    LP    T  L+
Sbjct: 229 -------SGPGATGTTLFPSHSATSVFVGEPKTSPI----TSASMETTALPGSTTTAGLS 277

Query: 378 NSNVDI--SKINEVLTAAVTQASLQSIIHKFLTA----GPS---AFNITSLISQAAQLST 428
             +     S  +   T +  + +   +  K  T+    GP+   AF  ++ +   +Q ST
Sbjct: 278 EKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQEST 337

Query: 429 QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP--LISTPPVSSQPKVSTPVVK 486
            +     S  +  S  ++  S + P  +T  ++    K   L      S   + STP V 
Sbjct: 338 ASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP-VH 396

Query: 487 QGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 546
               S   T  P ++   +G     P + Q   S +  SP P+ T+++        V  +
Sbjct: 397 SSTGSPHTTLSPSSSTTHEG----EPTTFQSWPSSKDTSPAPSGTTSA-------FVKLS 445

Query: 547 SSARSTCSLTPALAAHFS 564
           ++  S+ S TP    HFS
Sbjct: 446 TTYHSSPSSTP--TTHFS 461



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 74/402 (18%), Positives = 140/402 (34%), Gaps = 28/402 (6%)

Query: 189 REVMQATATSGFASGMEDKHS---SDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTP 245
           +  + ++  SG +      HS   +  ++L P +  +       +   +  A   +++ P
Sbjct: 209 KHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP 268

Query: 246 VQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTER 305
                  +   + T  + P SP    S  +   S  +  ++T    P PT ++    +  
Sbjct: 269 GSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 328

Query: 306 KESTSGDKPVSHSC--TTPSTSSASGLNPTSAPPTSASAVPVSP--VPQSPIPPLLQDPN 361
               S +   SHS   +T +T S     P+S  P S +    SP     + +P       
Sbjct: 329 MPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTT-FHSSPGYTKTTRLPDNTTTSG 387

Query: 362 LLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLIS 421
           LL    P   +T    + +  +S      +++ T     +    + ++  ++   +   S
Sbjct: 388 LLEASTPVHSST---GSPHTTLSP-----SSSTTHEGEPTTFQSWPSSKDTSPAPSGTTS 439

Query: 422 QAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVS 481
              +LST    S  S  +    ASS     S   STP  ++ P+    + PP  S     
Sbjct: 440 AFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE-STP-VHSSPVATATTPPPARS----- 492

Query: 482 TPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 541
                 G V +S          Q  H P S  +   S    +      HT +S+ ++ A 
Sbjct: 493 ---ATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAA 549

Query: 542 VVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQA 583
           +   ++S  S+   T       S  +    +   A H+   A
Sbjct: 550 LA--HTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDA 589


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 106/559 (18%), Positives = 199/559 (35%), Gaps = 69/559 (12%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS + P+  + R     +   PSP       +++ E   +++T  S A       +   +
Sbjct: 658  SSSAEPTEHEERTPLANENTTPSPAEP----TENRERTANENTTPSPAGPTENREMTANE 713

Query: 91   GGTSY--SPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYY 148
              T +   P EN    +A   + S  + P+ N  +T  A   +    +E      +    
Sbjct: 714  KTTLFPAEPTEN-RERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLA 772

Query: 149  NCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGMEDKH 208
            N  T +S    P E  ER   +K         FP +    RE      T+   S  +   
Sbjct: 773  NENTTLSP-AGPTENRERTANEK------TTPFPAEPTENRERTANENTT--PSPAQPTE 823

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPF 268
            + D + L  +      +   +   R P A   ++S+  +    P  H   TP    ++  
Sbjct: 824  NGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAE----PTEHAERTPL---ANEN 876

Query: 269  TLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSAS 328
            T  S  +P ++ +             T+  PA+ TE +EST+ +K      TTP  +  +
Sbjct: 877  TTSSPAEPTENRERTANEK-------TTQFPAEPTENRESTANEK------TTPFPAEPT 923

Query: 329  GLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLL------------RQLLPALQATLQL 376
                 +A   +  + P  P     + PL+ D NL             + +   + +T   
Sbjct: 924  ENREWTANENTTLS-PAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGS 982

Query: 377  NNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQ-AQPSNQ 435
             +S       +  ++ + T +S  S     +T   +A  ++S   +  + ST  ++P   
Sbjct: 983  ESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPVTA 1042

Query: 436  SPMSL-----------TSDASSPRSYVSPRISTPQTNTVPIKPLIS-------TPPVSSQ 477
            S ++L           T+ +S+  S  +   ++   NT   +  +S       T    + 
Sbjct: 1043 SILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASEDTT 1102

Query: 478  PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNA 537
                T V+    V  +AT+ P           V P++   S    +PS  PN  S +   
Sbjct: 1103 VSTQTSVIAAESVPHTATKTPTDTTTASVSATV-PKNNTLSVITSTPSTAPNTASKTMTT 1161

Query: 538  SNATVVPQNSSARSTCSLT 556
            ++ T      ++  T   T
Sbjct: 1162 ASKTTTTSTITSLPTTVFT 1180



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 98/500 (19%), Positives = 167/500 (33%), Gaps = 51/500 (10%)

Query: 54  PPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSH 113
           PP          + ++ ++T HSK  +  T   +  D  +S      + NH A  +S  +
Sbjct: 133 PPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSS------TDNHEAPPTSEEN 186

Query: 114 SSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEA 173
           SSN   +P   +    D AD  + H  S+GKK+            K         R+ + 
Sbjct: 187 SSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDK 246

Query: 174 NKMAVNSFPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYR 233
               +       D        T TS   SG  +  +   S+  P+ I + +         
Sbjct: 247 TGRPLEKSMSTLDKTSTSSHKTTTSFHNSG--NSQTKQKSTSFPEKITAASKTTYKTTGT 304

Query: 234 LPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPT 293
              +E    S       K +   T       S+    QS  +P +    +G  T ++  T
Sbjct: 305 PEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTE----HGGRTANENNT 360

Query: 294 PTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI 353
           P+   PA+ TE +E T+ +            ++ S   PT     +A+    +P P  P 
Sbjct: 361 PS---PAEPTENRERTANE-----------NTTLSPAEPTENRERTANE-NTAPFPAGPT 405

Query: 354 PPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSA 413
                  N    L PA         +N +            T +  +   H   TA    
Sbjct: 406 ENREMTANENTTLFPAEPTEHGERTANEN-----------TTPSPAEPTEHGERTANE-- 452

Query: 414 FNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPP 473
            N T   ++  +   +   +N    S  S A S        ++   T   P +P  +   
Sbjct: 453 -NTTPSPAEPTEHGERTPFANDKTTS--SSAESTEHGERTPLANENTTPSPAEPTENRER 509

Query: 474 VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGP-NHTS 532
            +++    +P    GP     T    TA+++    PV P   + +++    +P P   T 
Sbjct: 510 TANENTTPSPA---GPTENRET----TANEKTTLSPVEPTENRETTANEKTTPSPAEPTE 562

Query: 533 NSSNASNATVVPQNSSARST 552
           N      A     +SSA  T
Sbjct: 563 NGQRTPFANEKTTSSSAEPT 582



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 45/225 (20%), Positives = 86/225 (38%), Gaps = 28/225 (12%)

Query: 195  TATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVV 254
            TA+    +  +   +S  +SL P  + + TS+       +P A T  S+T          
Sbjct: 1154 TASKTMTTASKTTTTSTITSL-PTTVFTTTSKITAGS-EIPTASTTDSATTAISTKASGT 1211

Query: 255  HPTATPSTVPSSPFTLQSDHQPKKSF----DANGASTLSKLPTPTSSVPAQKTERKES-- 308
               + PST P +P    +   P  +     +  G  T+S +PT   +  ++ +   E+  
Sbjct: 1212 TVESAPSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTR 1271

Query: 309  ----------------TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 352
                            T+G +    S   P T++ SG +  +  P   +   VS    + 
Sbjct: 1272 ASTSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVMPAKTTTASVSTTASTT 1331

Query: 353  IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQA 397
            +     D   + + +P + +T+   + +  +SKI  V TA   +A
Sbjct: 1332 LYQNTIDS--VAKSVPTMDSTIA--SKSTTLSKIVSVPTAVFIKA 1372


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 103/512 (20%), Positives = 198/512 (38%), Gaps = 25/512 (4%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  S  D       D+ D S  +     SDS ++  S  +  SK+ +  +    E D
Sbjct: 577  SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS----ESD 632

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNC 150
               S S  ++S ++S+  S NS SS+ SN+ S +SD+   S    S   S S      + 
Sbjct: 633  SSDSDSKSDSSDSNSSDSSDNSDSSDSSNS-SNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 151  RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGMEDKHSS 210
             ++ S   +  +  +        +  + NS   D D       ++ +S  ++  +   SS
Sbjct: 692  SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD----SSNSSDSSDSSNSSDSSDSS 747

Query: 211  DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTL 270
            D+S+    +  S +S  +D       +++  SS              +  S+  S     
Sbjct: 748  DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN----------SSDSNDSSNSSDSSDS 797

Query: 271  QSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKEST-SGDKPVSHSCTTPSTSSASG 329
             +      S D++ +S  S   +  SS  +  ++  +S+ S D   S   +  S S +S 
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857

Query: 330  LNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEV 389
             + +S    S+ +   S    S       D N       +  ++   ++ + D S  ++ 
Sbjct: 858  RSDSSNSSDSSDSSDSSNSSDSSDS---SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914

Query: 390  LTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRS 449
              ++ +  S +S  +    +  S  + +S  S ++  S  +  SN S  S +SD+S   S
Sbjct: 915  SDSSNSSDSSES-SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973

Query: 450  YVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEP 509
              S   S    ++       S+    S     +        S +++    ++D     + 
Sbjct: 974  SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033

Query: 510  VSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 541
             S  S    SS  S S   + +SNSS++S+++
Sbjct: 1034 -SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 98/543 (18%), Positives = 207/543 (38%), Gaps = 70/543 (12%)

Query: 12  SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSD 71
           S G  D   DS        +S ++ S  +       D  D S   K   +SDS ++  SD
Sbjct: 507 SKGAEDDDSDS--------TSDTNNSDSNGNGNNGNDDNDKSDSGK--GKSDSSDSDSSD 556

Query: 72  STGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDS 131
           S+  S + +            +S S   +S++ S   SS+S SS+ S++ S  S    DS
Sbjct: 557 SSNSSDSSD------------SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604

Query: 132 ADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREV 191
           +D  S+   SS      + +++ S+ E      + +    ++N         D     + 
Sbjct: 605 SDS-SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS-------SDSSDNSDS 656

Query: 192 MQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
             ++ +S  +   +   SSD+SS    +  S +S  +D       +++  SS        
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716

Query: 252 PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
              +  ++ S   +S  +  S +    S  ++ +++     +  SS  +  ++  +S+  
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776

Query: 312 DKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQ 371
               + S +  S++S+   + +++  +S S+                             
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS----------------------------D 808

Query: 372 ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
           ++   ++S+ D S  ++   ++ +  S  S          S+ +  S     +  S ++ 
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNS--------SDSSDSSDSSDGSDSDSSNRSD 860

Query: 432 PSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVS 491
            SN S  S +SD+S+         S   +N+       ++    S    ++        S
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 492 QSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARS 551
             +++   ++D        S  S    SS  S S   + +SNSS++SN++    ++S+ S
Sbjct: 921 SDSSESSNSSDNSNS----SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 552 TCS 554
           + S
Sbjct: 977 SDS 979



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 99/533 (18%), Positives = 196/533 (36%), Gaps = 24/533 (4%)

Query: 12   SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENK-YS 70
            S    D + DS   ++    S S   S D       D  D S  +     SDS ++   S
Sbjct: 616  SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675

Query: 71   DSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDA--P 128
            DS+  S + N         D   S +  E+S +  +  S +S SS+ SN+ S  SD+   
Sbjct: 676  DSSSSSDSSNSSD----SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731

Query: 129  YDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYR 188
             DS+D  +   SS       +  +  S                +++  + +S   D    
Sbjct: 732  SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791

Query: 189  REVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQH 248
             +   ++ +S  ++  +   SSD+S     N    ++  +  D       + SS +    
Sbjct: 792  SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES 308
                     ++ S+  S      +      S D+N +S  S     ++S  +  ++   S
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 911

Query: 309  TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 368
            +      + S ++ S++S+   N + +  +S S+   S    S       D +       
Sbjct: 912  SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS-DSSDSSNSSDSSNSSDSSNSSDSSD 970

Query: 369  ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST 428
            +  +    ++++ D S  ++   ++ +  S  S       +  S  + +S  S ++  S 
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS-------SDSSDSSDSSDSSNSSDSSN 1023

Query: 429  QAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQG 488
             +  SN S  S +SD+S          S+  +N        S+    S     +      
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN--------SSDSSDSSDSSDSSDSSDS 1075

Query: 489  PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 541
              S  +++   ++D     +  S  S    SS  S S   + +S+SSN+S+++
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 102/530 (19%), Positives = 199/530 (37%), Gaps = 36/530 (6%)

Query: 12   SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSD 71
            S    D    S    +   SSKS   S D   +   D+ D +        SDS +N  SD
Sbjct: 607  SSDSSDSSDSSDSSDSKSDSSKSESDSSD--SDSKSDSSDSN-------SSDSSDN--SD 655

Query: 72   STGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDS 131
            S+  S + N         D   S    ++S +  + +SS+S  S+ S+N S++SD+   S
Sbjct: 656  SSDSSNSSN-------SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708

Query: 132  ADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREV 191
              D S+   SS      N     S                +++  + +S   D       
Sbjct: 709  DSDSSDSSDSSNS----NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764

Query: 192  MQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
              ++ +S  +   +  +SSD++     +  S +S  +D       +++  SS        
Sbjct: 765  SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824

Query: 252  PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSG 311
               + + +  +  SS  +  SD       D++  S  S     + S  +  +     +S 
Sbjct: 825  DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 312  DKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQ 371
                S+S  +  +S++S  + + +  +S S+   +    S       + N       +  
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 372  ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
            +    ++++ D S  ++   ++ +  S  S      ++  S  + +S  S ++  S  + 
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD-----SSDSSNSSDSSDSSDSSDSSDSSD 999

Query: 432  PSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVS 491
             SN S  S +SD+S   +      S+  +N+       S    SS    S+        S
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS-------SDSSDSSDSSDSSDSSDSSDSS 1052

Query: 492  QSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNAT 541
             S+     ++D     +  S  S    SS  S S   + +SNSS++S+++
Sbjct: 1053 DSSNSSD-SSDSSDSSDS-SDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 59/334 (17%), Positives = 120/334 (35%), Gaps = 27/334 (8%)

Query: 12   SDGCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSD 71
            SD      G          SS S  SS         D+ D S  N+    SDS ++  S 
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 72   STGHSKAKNVH--THRVRERDGGTSYSPQENSHNHSALHSSNSH-SSNPSNNPSKTSDAP 128
             +  S + N    +      D   S +  +NS++  + +SS+S  SS+ SN+   ++ + 
Sbjct: 902  DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 129  YDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYR 188
              ++ D S+  SS                               ++  + +S   D    
Sbjct: 962  SSNSSDSSDSNSSDSSD------------------------SSNSSDSSDSSDSSDSSDS 997

Query: 189  REVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQH 248
             +   ++ +S  +   +  +SSD+S+    +  S +S  +D       +++  SS     
Sbjct: 998  SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057

Query: 249  PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES 308
                    ++  S    S  +  S      S  +N + +     +  SS  +  ++  +S
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 309  TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASA 342
            +        S ++ S+ S+   N + +  +S S+
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 97/542 (17%), Positives = 200/542 (36%), Gaps = 32/542 (5%)

Query: 22  SQPYQALKYSSKSHPSSGDHRH-----EKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHS 76
           S+P   + +S+    S+ D        +K     DP+  ++     D+  N  SD+   S
Sbjct: 430 SEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDA--NSESDNNSSS 487

Query: 77  KAK-NVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSS------NPSNNPSKTSDAPY 129
           +   + ++   ++   G+     E+  + S   ++NS S+      N  N+ S +     
Sbjct: 488 RGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547

Query: 130 DSAD-DWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYR 188
           DS+D D S+  +SS      +  +  S      +  + +      +  + +S   D    
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607

Query: 189 REVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQH 248
            +   ++ +S  +    D   S++ S          S+ +  D     +  +S S+   +
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDS------SDSDSKSDSSDSNSSDSSDNSDSSDSSN 661

Query: 249 PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES 308
                    ++ S+  SS     +      S D++ +S  S     + S  +  ++   S
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 309 TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLP 368
            S D   S+S  +  +S++S  + +S    S+ +   S    S       D +       
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS------- 774

Query: 369 ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLST 428
               +   +NS+      N   ++  + +S  S       +  S+ + +S  S ++  S 
Sbjct: 775 ---DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 429 QAQPSNQSPMSLTSDAS-SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQ 487
            +  SN S  S +SD+S    S  S R  +  ++        S    SS    S      
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 488 GPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS 547
              S S+      +         S  S    SS+ S S   +++S+SSN+S+++    +S
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 548 SA 549
           ++
Sbjct: 952 NS 953



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 44/215 (20%), Positives = 80/215 (37%), Gaps = 2/215 (0%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  S  +  S   +  +      D
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDA--PYDSADDWSEHISSSGKKYYY 148
               S    ++S +  +  SSNS  S+ S++ S +SD+    DS+D      SS       
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161

Query: 149  NCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGMEDKH 208
            +  +  S                +++  + +S   D     +   ++ +S  +   +   
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSS 243
            SSD+S     N  S +S  +D       +++  SS
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256



 Score = 33.1 bits (74), Expect = 0.82
 Identities = 23/104 (22%), Positives = 44/104 (42%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS E+  S  +  S   +  +      D
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADD 134
               S S   +  +  +   + +++ + S++ S+ SD+ + ++DD
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 25/111 (22%), Positives = 41/111 (36%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            SS S  SS         D+ D S  +     SDS ++  S  +  S   +  +      +
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISS 141
               S    ++S + S  +  +   S   N  +  SD+  DS    S H +S
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 84/362 (23%), Positives = 120/362 (33%), Gaps = 57/362 (15%)

Query: 221 LSQTSRHNDRDYRLPRAETHSSS--------------TPVQHPIKPVVHP-TATPSTVPS 265
           LS  +R        PRA  H S               TP +    P + P +++P   PS
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 266 SPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTS 325
              T      P  +      +TL   P   + +P          S     S   T PS +
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368

Query: 326 SASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK 385
             S   P    P S   +P   VP S   P LQ P      L +LQAT  L +  +  + 
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS-PLALSSLQATTSLGSPTLQATH 427

Query: 386 INEVLTAAVTQASLQSI------------------------IHKFLTAGPSAFNITSLIS 421
               ++   TQASL S                         +   L+   S  +    I 
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487

Query: 422 QAAQLSTQAQPSNQSPMS--LTSDASSPRSYVSPRISTPQTN--TVPIK--PLISTPPVS 475
               LS+ A  S Q+P+S  +     +  S   P + TP  +  T P++  P ++ PP+ 
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547

Query: 476 SQ-----------PKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
           +            P    P   Q P S   T  P T        P +P +L     Q  P
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607

Query: 525 SP 526
           SP
Sbjct: 608 SP 609



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 80/335 (23%), Positives = 114/335 (34%), Gaps = 29/335 (8%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
           P+A    +S P+Q    P + P ATP         L     P        +  LS L TP
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP---PASPPLSPLATP 648

Query: 295 TSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP 354
           +   P              P       PS    +  +P ++PP S SA P S  P S   
Sbjct: 649 SPQAPNALAVHLLQAPFSPP-------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701

Query: 355 PLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAF 414
           P LQ P       P+  A+  ++ S     +    L A   Q          ++   +  
Sbjct: 702 PPLQVP-------PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754

Query: 415 NITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPV 474
                +  A  L     P    PM   S  + P     P ++TP    +P  P       
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPM---SPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811

Query: 475 SSQPKVSTPVVKQGPVSQSATQ-QPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSN 533
              P  S P+    P++    Q  PV A       P  P S    + +R P+PGP+ + +
Sbjct: 812 PFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868

Query: 534 SSNASNATV----VPQNSSARSTCSLTPALAAHFS 564
               + A       P + S  ST S  P LA H S
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSS 902


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 96/386 (24%), Positives = 142/386 (36%), Gaps = 76/386 (19%)

Query: 233  RLPRAETHSSSTPVQHP--IKPV---VH---PTATPSTVPSSPFTLQSDHQPKKSFDANG 284
            RLP     ++  P+  P  ++P+   VH   P  + S   ++P T+ S      S     
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411

Query: 285  ASTLSKLPTPTSSVPAQKTERKEST--SGDKPVSHSCTTPSTSSASGLNPTSAPPTSASA 342
            +S +   P P SS  A       S   S   P+S   T P+ +SA    P SAP T +++
Sbjct: 1412 SSPM---PIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSAS 1468

Query: 343  VP-----VSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQA 397
             P     V+P P +P+ P    P            +L  + ++   S +   L  A + +
Sbjct: 1469 GPALLTSVTP-PLAPVVPAAPGP-----------PSLAPSGASPSASALTLGLATAPSLS 1516

Query: 398  SLQSIIHKFLTAGPSAFNITSLISQAAQL--------STQAQPSNQSPMSLTSDAS--SP 447
            S Q+  H  L A P++ ++  L S  A          S  A P   +P    + AS  +P
Sbjct: 1517 SSQTPGHPLLLA-PTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAP 1575

Query: 448  RSYVSPRISTP-------QTNTV---PIKPLISTPPVSSQPKVS-------TPVVKQGPV 490
             S  S  ++TP       QT  +   P  PL   P ++  P  +       TPV    P 
Sbjct: 1576 ASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPS 1635

Query: 491  SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSN----------------- 533
            S   T     +        ++P S Q       PSP P+  S                  
Sbjct: 1636 STPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSS 1695

Query: 534  -SSNASNATVVPQNSSARSTCSLTPA 558
             S   S  T  PQ      T SLTPA
Sbjct: 1696 PSQTLSLGTGNPQGPFPTQTLSLTPA 1721



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 85/346 (24%), Positives = 125/346 (36%), Gaps = 55/346 (15%)

Query: 237  AETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKK-SFDANGASTLSKLPTPT 295
            A T S    +   + P   P   P++  +SPF    +  P + S  A  +S    L TP 
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPL 1587

Query: 296  SSVPAQKTERKE------------------------STSGDKPVSHSCTTPSTSSASGLN 331
            + + A +T                            S+    PV    +TP TS AS  +
Sbjct: 1588 APMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA-S 1646

Query: 332  PTSAP-----PTSASAVPVSPVPQS-PIPPLLQDPNLLRQLLPAL-----QATLQLNNSN 380
            P  AP     P+S   +  +PVP   P P   Q   L   L P L       TL L   N
Sbjct: 1647 PVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGN 1706

Query: 381  VDISKINEVLTAAVTQASLQSIIHKF-LTAGPSAFNITSLISQAAQLSTQAQPSNQSPM- 438
                   + L+     + + +      L  GP      +L    A     A P   +P  
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH 1766

Query: 439  SLT-SDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQS---- 493
            +LT + ASS  S ++P  ++ QT T+   P+ +  P ++Q     P   Q P SQ+    
Sbjct: 1767 TLTLAPASSSASLLAP--ASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLV 1824

Query: 494  -----ATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNS 534
                 A   PVT   +       P +L    + RS  P P  T+ S
Sbjct: 1825 VSASGAAPLPVTMVSRLPVSKDEPDTL----TLRSGPPSPPSTATS 1866



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 72/303 (23%), Positives = 105/303 (34%), Gaps = 47/303 (15%)

Query: 245  PVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTE 304
            P   P  PV+ P   P++  S P  L S              TLS  PTP + V      
Sbjct: 1062 PASRPPGPVLLPPLQPNS-GSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAP 1120

Query: 305  RKESTSGDKP--VSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNL 362
               S+S  KP  V    T P  ++ +    T+   T+A   P +P PQ  I         
Sbjct: 1121 PPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAP-TPAPQRLI--------- 1170

Query: 363  LRQLLPALQATLQLNNSNVDISKINEVLTAAVTQA------SLQSIIHKFLTAG------ 410
               L P +QA L  +   V I ++  +    V  A      + Q   +K    G      
Sbjct: 1171 ---LSPDMQARLP-SGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQL 1226

Query: 411  ------PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVP 464
                  P   N+  L+S   Q    +QP++ + +   +    P        STP T   P
Sbjct: 1227 AVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAP 1286

Query: 465  IKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
                +   P+++     T V   G V     Q P     + G  PV P     + + R P
Sbjct: 1287 TGLSL---PLAANQVPPTMVNNTGVVKIVVRQAP-----RDGLTPVPP----LAPAPRPP 1334

Query: 525  SPG 527
            S G
Sbjct: 1335 SSG 1337



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 67/339 (19%), Positives = 117/339 (34%), Gaps = 69/339 (20%)

Query: 233  RLPRAETHSSSTPVQHPIK-PVVHPTATPSTVPSS---PFTLQSDHQPKKSFDANGASTL 288
            R+PR       TP   P   P + P    + VP S   P T+   H             +
Sbjct: 2435 RVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVH-------------I 2481

Query: 289  SKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPV 348
               P P S +P                S +CT P         P   PP + +  P    
Sbjct: 2482 LPSPPPPSQIPPCS-------------SPACTPP---------PACTPPPAHTPPPAQTC 2519

Query: 349  PQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
              +P  PLL  P       P++  +  + N  + +    E+   A+  AS +S+  +  +
Sbjct: 2520 LVTPSSPLLLGP-------PSVPISASVTNLPLGLRPEAELCAQAL--ASPESL--ELAS 2568

Query: 409  AGPSAFNITSLI--SQAAQLSTQAQPSNQSPMSLTSDASS--------PRSYVSPRISTP 458
               S  +  SL+       ++ +  P ++  +SLT  A S        P         + 
Sbjct: 2569 VASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSA 2628

Query: 459  QTNTVPIKP--------LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPV 510
            +  T+ + P        +  +  +   P  ++    Q P+    T + +T  K     P 
Sbjct: 2629 EGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPE 2688

Query: 511  SPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA 549
             P+ L  ++   +PS   + TS+    S A    + +SA
Sbjct: 2689 KPQELV-TAEVAAPSTSSSATSSPEGPSPARPPRRRTSA 2726



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 48/187 (25%), Positives = 69/187 (36%), Gaps = 13/187 (6%)

Query: 264  PSSPFTLQS-DHQPKKSFDANGASTLSKLPTP------TSSVPAQKTERKESTSGDKPVS 316
            P  PF  Q+    P  S     A TLS  P P      T S+         S  G  P  
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH 1766

Query: 317  HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA-TLQ 375
                 P++SSAS L P S    + S  PV  +  +    L   P   +   PA QA +L 
Sbjct: 1767 TLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQS--PASQASSLV 1824

Query: 376  LNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQ 435
            ++ S      +  V    V++    ++    L +GP +   T+      +   Q  P  +
Sbjct: 1825 VSASGAAPLPVTMVSRLPVSKDEPDTLT---LRSGPPSPPSTATSFGGPRPRRQPPPPPR 1881

Query: 436  SPMSLTS 442
            SP  L S
Sbjct: 1882 SPFYLDS 1888



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 42/153 (27%), Positives = 56/153 (36%), Gaps = 35/153 (22%)

Query: 238  ETHSSSTPVQHPIKP---VVHPTATPST---VPSSPFTLQSDHQPKKSFDAN-------- 283
            E   + TP   P KP   V    A PST     SSP        P++   A+        
Sbjct: 2676 ELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGT 2735

Query: 284  -------GASTLSKLPTPTSSVPAQKT------ERKESTS----GDKPVSHSCTTPSTSS 326
                   G   L KLP    +V  +K       +++ + S    G    S S  +PS  S
Sbjct: 2736 GRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRS 2795

Query: 327  ASGLNPTSAPPTSA--SAVPVSPVPQSPIPPLL 357
             SG  P S+PP      A P S +P  P  P +
Sbjct: 2796 MSG--PESSPPIGGPCEAAPSSSLPTPPQQPFI 2826


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 78/367 (21%), Positives = 134/367 (36%), Gaps = 59/367 (16%)

Query: 202  SGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPS 261
            + +E  H S  +S    N+ + +S H  +   L  +E   ++ P+      + H T + S
Sbjct: 6875 TAIEAMHPS--TSTAATNVETTSSGHGSQSSVLADSEKTKATAPMD-TTSTMGHTTVSTS 6931

Query: 262  TVPSS--------------PFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKE 307
               SS              P   ++      SF  + +  LS++PT T++  ++      
Sbjct: 6932 MSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSS 6991

Query: 308  STSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLL 367
              +     S S   P  S+ +     ++P  + SA    P    P     QD        
Sbjct: 6992 GRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQD-------- 7043

Query: 368  PALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQA-AQL 426
                                  LT   +    Q+  H  LT       +T+L+S+    +
Sbjct: 7044 ---------------------TLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDM 7082

Query: 427  STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVK 486
            S Q+ PS ++P SL S  S P +   P IS+    T+   PL  T  ++S P  +T ++ 
Sbjct: 7083 SWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLH 7142

Query: 487  QGP---------VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG---PNHTSNS 534
              P         +S ++ ++  T       E V P +   +S+   PS G   P+     
Sbjct: 7143 TSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALAD 7202

Query: 535  SNASNAT 541
            S  S AT
Sbjct: 7203 SETSKAT 7209



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 101/479 (21%), Positives = 171/479 (35%), Gaps = 33/479 (6%)

Query: 97   PQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQ 156
            P  +    SA     + +  P + P  T      +  +W E  S+  +++ ++  T +  
Sbjct: 8187 PTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVS 8246

Query: 157  WEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATSGFASGMEDKHSSDASSLL 216
               P + L   Q   E    A +            + +T    F S      S   +SLL
Sbjct: 8247 -RSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSA-----SLPVTSLL 8300

Query: 217  PQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQP 276
               ++  T R      R P   + S+ +   H     +  T     +  S  T  ++ + 
Sbjct: 8301 NPGLVITTDRMGIS--REPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRT 8358

Query: 277  KKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTT------PSTSSASGL 330
              S   + +S LS   TP ++ P   T     TS     S    T      P++S  SGL
Sbjct: 8359 SISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGL 8418

Query: 331  NPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVL 390
              TS+    +SA   S V      P      + R  + + + T         IS   ++ 
Sbjct: 8419 RETSSSERISSATEGSTVLSEV--PSGATTEVSRTEVISSRGTSMSGPDQFTISP--DIS 8474

Query: 391  TAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY 450
            T A+T+ S   I+ +   +  SA  I +    A    T    ++ +     + +++   +
Sbjct: 8475 TEAITRLSTSPIMTE---SAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGF 8531

Query: 451  VSPRISTPQTNTVPIKPLISTPPV----------SSQPKVSTPVVKQGPVSQSATQQPVT 500
                ++T  + T    P  S P V          SS    ST      P S S++  PVT
Sbjct: 8532 SHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVT 8591

Query: 501  ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPAL 559
            A    G  PV    + R+SS+   S  PN +S S+     + V ++       S TP +
Sbjct: 8592 ALLTLG--PVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVV 8648



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 76/353 (21%), Positives = 137/353 (38%), Gaps = 33/353 (9%)

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAE-THSSSTPVQHPIKPVVHP-TATPSTVPSS 266
            SSD S++  +   + T+        + R E T SS T +Q   KP + P T+T S    S
Sbjct: 6380 SSDTSTVFDKAFTAATTE-------VSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLS 6432

Query: 267  PFTLQSDHQPKKSFDANG---ASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPS 323
             F   +  + +      G   A++   L   TS   +Q       T G   +  S  T  
Sbjct: 6433 TFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSR 6492

Query: 324  TSS-ASGLNPTSAPPTSASAVPVS-PVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNV 381
                 SG +P S   TS+S+  +S P   SP P     P  L +  P+    L    ++ 
Sbjct: 6493 VPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPV----PTTLPESRPSSPVHLTSLPTSG 6548

Query: 382  DISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLT 441
             +   + + + A    +L S  HK  T      +   +        T    +     S +
Sbjct: 6549 LVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYS 6608

Query: 442  SDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKV------STPVVKQGPVSQSAT 495
            S    P     P++++P   +  I+  I +  +    ++      ST  +  G    S +
Sbjct: 6609 S---VPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTS 6665

Query: 496  QQPVTADKQQG--HEPVSPRS----LQRSSSQRSPSPGPNHTSNSSNASNATV 542
            Q P+ + ++    H+  +  +     + +SS+R+  PGP+H++ S + S   +
Sbjct: 6666 QDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVI 6718



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 114/564 (20%), Positives = 195/564 (34%), Gaps = 81/564 (14%)

Query: 31    SSKSHPSSG---------DHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNV 81
             + K HPSS             HE        S P+K      +P +    S   S   N 
Sbjct: 10093 TEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANF 10152

Query: 82    HTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISS 141
              T         T +  +  SH  S    +N      S  P+ T  +P       S H+  
Sbjct: 10153 ET---------TGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSP------GSTHLLQ 10197

Query: 142   SGKK-YYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQA-TATSG 199
             S K  +  + +T    W    ++ E                P D         + T ++G
Sbjct: 10198 SSKTDFTSSAKTSSPDWPPASQYTE---------------IPVDIITPFNASPSITESTG 10242

Query: 200   FASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSST--PVQHPIKPVVHPT 257
               S  E + +           +++++ H   D  LP AET S+ T  P           T
Sbjct: 10243 ITSFPESRFTMS---------VTESTHHLSTDL-LPSAETISTGTVMPSLSEAMTSFATT 10292

Query: 258   ATPSTVPSS--PFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPV 315
               P  +  S  PF+         +      S  S  P P SS     T+     +  +  
Sbjct: 10293 GVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEIT 10352

Query: 316   SHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIP------PLLQDPNLLRQLLPA 369
             S S T     ++ G   T +  T    V VS +  S  P      P+L         L  
Sbjct: 10353 SSSATPYRVDTSLG---TESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGT 10409

Query: 370   LQATLQLNNSNVDISK---INEVLTAAVTQASLQSIIH-----KFLTAGPSAFNITSLIS 421
             + +  Q+ + +  +++   I E +T    +A+ +  I      +  T+  S   + +  +
Sbjct: 10410 VTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGT 10469

Query: 422   QAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIST--------PQTNTVPIKPLISTPP 473
             +  + +T A  +  + +  TS A+   S  +P + T           +T+P + +I+TP 
Sbjct: 10470 KRMETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPY 10529

Query: 474   VSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSL-QRSSSQRSPSPGPNHTS 532
             V      +T  +     ++++T  P T       E  +  SL  RS ++RSP       S
Sbjct: 10530 VFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVS 10589

Query: 533   NSSNASNATVVPQNSSARSTCSLT 556
             +S   + A+ V   +    T S T
Sbjct: 10590 SSEPDTTASWVIHPAETIPTVSKT 10613



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 81/394 (20%), Positives = 141/394 (35%), Gaps = 83/394 (21%)

Query: 234  LPRAETHSSST----PVQHPIKPVVHPTATPSTVPSSPFTLQS-------------DHQP 276
            + R E  S+ST    P +      +H    PSTVP    T  +                P
Sbjct: 8989 ITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSP 9048

Query: 277  KKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTT----PSTSSASGLNP 332
             +S  +   ST       TS +  + TE   +T    P + S  T     ST+  SG + 
Sbjct: 9049 DQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHS 9108

Query: 333  TSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTA 392
            T++   S S +           P L  P++      +   +  +  S+   S ++  L  
Sbjct: 9109 TASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSS---SPVSSTLPD 9165

Query: 393  AVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS------- 445
            ++  +SL   +   LT+G        L+     L T ++P   SP +L+S ++       
Sbjct: 9166 SIHSSSLP--VTSLLTSG--------LVKTTELLGTSSEPETSSPPNLSSTSAEILAITE 9215

Query: 446  ---------------------SPRSYVSPRISTPQTNTVPI-------KPLISTPPVSSQ 477
                                 SP S ++  ++T  T+++ I         L STP  S  
Sbjct: 9216 VTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDT 9275

Query: 478  PKVS-------TPVVKQGPVSQ---SATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 527
             ++        TP + +  +S+   SAT++                  +  SS R+  PG
Sbjct: 9276 SRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPG 9335

Query: 528  PNHTSNSSNASNATV----VPQNSSARSTCSLTP 557
            P  ++ SS+ S  T+     P      +  ++TP
Sbjct: 9336 PAQSTMSSDTSMETITRISTPLTRKESTDMAITP 9369



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 99/489 (20%), Positives = 167/489 (34%), Gaps = 63/489 (12%)

Query: 114  SSNPSNNPSKTSD---APYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQ 170
            +S+P N  S T +      D+A   + H S        N  T +S  E            
Sbjct: 5684 TSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTS 5743

Query: 171  KEANKMAVNSFPKDRDYRREV-------MQATATSGFASGMEDKHSSDASSLLPQNILSQ 223
            K  + M +     D              +Q  +TS    G+ D  +S+  + + +     
Sbjct: 5744 KATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVL 5803

Query: 224  TSRHNDRDYRLPRAETHSSS-TPVQHPIKPVVHP---TATPSTVPSSPFTLQSDHQPKKS 279
            +         + R E  +SS T +  P    + P   T T + + + PF   S       
Sbjct: 5804 SEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAI-- 5861

Query: 280  FDANGASTLSKLPTPTSSVPAQKTERKESTSGDK----PVSHSCTTPSTSSASGLNPTSA 335
               N    +  +   T ++    T   E T        P S   TT S S+  G++  S 
Sbjct: 5862 --TNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRST-KGVSWQSP 5918

Query: 336  PPTSASAVPVSPVPQSPIPPLLQDPNLLRQL--------LPALQATLQLNNSNVD-ISKI 386
            P    ++ P SPVP   +P +    +L   +        LP            +D +   
Sbjct: 5919 PSVEETSSPSSPVP---LPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTH 5975

Query: 387  NEVLTAAVTQAS--------------LQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQP 432
            +E++T+++  AS               ++I     TA  +     S+    + +S  +QP
Sbjct: 5976 SELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQP 6035

Query: 433  SNQSPMSLTSDASSPRSYVSPRISTPQTNTV------PIKPLI---STPPVSSQPKVSTP 483
            S  +P  +T          +    +P+T  V      P+ P +   ST  V +    S  
Sbjct: 6036 SGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNT 6095

Query: 484  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV 543
            V     VS  A  +   A+         P S Q   S +SP   P  +S+ SN+   T+ 
Sbjct: 6096 VFSS--VSLDAATEVSRAEVTYYDPTFMPASAQ---STKSPDISPEASSSHSNSPPLTIS 6150

Query: 544  PQNSSARST 552
               + A  T
Sbjct: 6151 THKTIATQT 6159



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 83/386 (21%), Positives = 148/386 (38%), Gaps = 46/386 (11%)

Query: 192   MQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK 251
             ++  A S   +  E  H S  SS+   N+ + +S H          E +SS +    P K
Sbjct: 10081 VEILAASEVTTDTEKIHPS--SSMAVTNVGTTSSGH----------ELYSSVSIHSEPSK 10128

Query: 252   PVVHPTATPSTVPSSPF-TLQSDHQPKKSFDANGASTLSK------LPTPTSSVPAQKTE 304
                +P  TPS++  +   T    +     F+A   S L+       +   TSSV    T 
Sbjct: 10129 -ATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTP 10187

Query: 305   RKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPV-PQSPIPPLLQDPNLL 363
                S+ G   +  S  T  TSSA   +P   P +  + +PV  + P +  P + +   + 
Sbjct: 10188 ---SSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGIT 10244

Query: 364   RQLLPALQATLQLNNS----NVDISKINEVLTAAVTQASLQSIIHKFLTAG-PSAFNITS 418
                 P  + T+ +  S    + D+    E ++      SL   +  F T G P A  I+ 
Sbjct: 10245 S--FPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRA--ISG 10300

Query: 419   LISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP 478
               S  ++  +    +  S ++ +  +S+P  + S   +T  ++T+P    I T   ++  
Sbjct: 10301 SGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEI-TSSSATPY 10359

Query: 479   KVSTPVVKQGPVSQSATQQPVTAD--KQQGHEPVSPRSLQR----------SSSQRSPSP 526
             +V T +  +   ++       T D   Q G    SP    R          +S+ + PS 
Sbjct: 10360 RVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSL 10419

Query: 527   GPNHTSNSSNASNATVVPQNSSARST 552
                 T       + T +P  ++ R T
Sbjct: 10420 STRLTRTDGIMEHITKIPNEAAHRGT 10445



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 91/404 (22%), Positives = 151/404 (37%), Gaps = 74/404 (18%)

Query: 200   FASGMEDKHSSDASSLLPQNILSQ----TSRHNDRDYRLPRAETHSSSTPVQHPIKPVVH 255
             F SG     S   S     N++S+     S  + R     R+ +  +S P+   + PV  
Sbjct: 9685  FLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSS 9744

Query: 256   PTATPSTVPSSPF---------------TLQSDHQPKKSFDANGASTLSKLP------TP 294
                  S  PSSP                 L +  +PK S   N +ST  ++P      T 
Sbjct: 9745  TLLDSS--PSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTD 9802

Query: 295   TSSV-PAQKTE-RKESTSGDKPVSHSC---------TTPSTSSASGLNPTSAPPTSASAV 343
             T  + P+  T   K  TS     SHS          T PS    S ++ T+   ++ +  
Sbjct: 9803  TEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFS 9862

Query: 344   PVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVL----TAAVTQASL 399
                 +P  P             L P  + T   +     I++ + VL    T+A T+ S+
Sbjct: 9863  ETRRIPTEPT----------FSLTPGFRET-STSEETTSITETSAVLYGVPTSATTEVSM 9911

Query: 400   QSIIHKFLTAGPSAFNIT---SLISQA-AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRI 455
               I+       P +   T    +I++   +LS+ +  S  + M++T+  SSP +     +
Sbjct: 9912  TEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTL 9971

Query: 456   STPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSL 515
              T  T T P+    ST P        T ++ + P + S                 S   +
Sbjct: 9972  -TLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWK---------------SSLFV 10015

Query: 516   QRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPAL 559
             +++SS  S    P  TS S +++    +P +SS   T  LTP +
Sbjct: 10016 EKTSSSSSLLSLPVTTSPSVSSTLPQSIP-SSSFSVTSLLTPGM 10058



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 63/322 (19%), Positives = 112/322 (34%), Gaps = 21/322 (6%)

Query: 237   AETHSSSTPVQHPIKPVVHPTATPSTVPSS---PFTLQSDHQPKKSFDANGASTLSKLPT 293
             ++  SS+T     I  +      P T  SS   P T      P ++  ++   T++   T
Sbjct: 11633 SQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVT 11692

Query: 294   --PTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPP---------TSASA 342
               P +S P  +T    S S         T+P T ++S +  T +P          TS+ A
Sbjct: 11693 HPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGA 11752

Query: 343   VPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSI 402
                + VP     P + +   L    P  + +     S V   +++E   +   +   ++ 
Sbjct: 11753 ATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTV-FPQVSETTASLTIRPGAETS 11811

Query: 403   IHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNT 462
                      S F +    +    LS  A P   +  +  S      +      ST     
Sbjct: 11812 TALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGL 11871

Query: 463   VPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR 522
             +    L++T   S++   ST  +   P     +   +T DK     P +  S    +S  
Sbjct: 11872 LETTGLLATSS-SAETSTSTLTLTVSPAVSGLSSASITTDK-----PQTVTSWNTETSPS 11925

Query: 523   SPSPGPNHTSNSSNASNATVVP 544
               S GP   S +   +  T++P
Sbjct: 11926 VTSVGPPEFSRTVTGTTMTLIP 11947



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 82/333 (24%), Positives = 136/333 (40%), Gaps = 54/333 (16%)

Query: 241  SSSTPVQHPIKPVVHPTATPST------VPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            +SS+PV   +   +H ++ P T      +  +   L +  +P+ S   N +ST +++   
Sbjct: 9154 TSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEILAI 9213

Query: 295  TSSVPAQKTERKEST----------SGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVP 344
            T       TE+ E T          S    ++ S TT +TSS     PT       S   
Sbjct: 9214 TEVTT--DTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPA 9271

Query: 345  VSPVPQSPIPPLLQDPNLLRQLLPALQATL---QLNNSNVDISKINEVLTAAVTQASLQS 401
             S   +      +Q  + L  L P L  T    + +++    + ++ V T A T+ S   
Sbjct: 9272 FSDTSR------IQTKSKL-SLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTE 9324

Query: 402  IIHKFLTA--GPSAFNITSLISQAA--QLSTQAQPSNQSPMSLT-----SDASSPRSYVS 452
             I    T+  GP+   ++S  S     ++ST       + M++T     S A+S  ++  
Sbjct: 9325 AISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTL 9384

Query: 453  PRIST---PQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEP 509
               ST   P T++       +T     Q  V+TP+  +GP   S    P++ +K      
Sbjct: 9385 DSSSTASWPGTHS-------ATTQRFPQSVVTTPM-SRGPEDVS-WPSPLSVEKNS---- 9431

Query: 510  VSPRSLQRSSSQRSPSPGPNHTSNSSNASNATV 542
              P SL  SSS  SPSP  +  S SS++S   V
Sbjct: 9432 -PPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPV 9463



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 79/371 (21%), Positives = 134/371 (36%), Gaps = 67/371 (18%)

Query: 209  SSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVP---S 265
            ++ A S +P   ++Q SR           E  SS T +    +P + P  +   +    +
Sbjct: 5504 TNTAFSYVPTGAITQASR----------TEISSSRTSISDLDRPTIAPDISTGMITRLFT 5553

Query: 266  SPFTLQSDHQPKKSFDAN-GASTLSKLPTPTSSVPAQK---------------TERKEST 309
            SP   +S      +     GA++   LP  TS+   Q                T  +  T
Sbjct: 5554 SPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRT 5613

Query: 310  SGD------KPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPI--PPLLQDPN 361
             GD       PV  + +  S  S S  +P+    TS  ++P SP+P + +    L+   N
Sbjct: 5614 PGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTN 5673

Query: 362  LLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNI-TSLI 420
            +L    P    +   N S+    ++      A T+A     +H  +    +  N+ TS+ 
Sbjct: 5674 VLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEA-----MHASMHTNTAVANVGTSIS 5728

Query: 421  SQAAQLSTQAQPSNQ---SPMSL------TSDASSPRSYVSPRISTPQTNTVPIKPLIST 471
               +Q S  A        SPM +      TS ++S  ++   RI T  T+        S 
Sbjct: 5729 GHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTS--------SL 5780

Query: 472  PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHT 531
             P     + S  +      S   ++ P T   +     V        +S R+   GP+H+
Sbjct: 5781 IPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEV-------ITSSRTTISGPDHS 5833

Query: 532  SNSSNASNATV 542
              S   S  T+
Sbjct: 5834 KMSPYISTETI 5844



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 80/375 (21%), Positives = 132/375 (35%), Gaps = 37/375 (9%)

Query: 169  RQKEANKMAVNSFPKDRDYR-REVMQATATSGFASGMEDKHS-----SDASSLLPQNILS 222
            R +E +    +SFP D  +   +V   T T   ++G+           D S++ P     
Sbjct: 5191 RLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTG 5250

Query: 223  QTSRHNDRDYRLPRAE---THSSSTP--VQHPIKPVVHPTATPSTVPSSPFTLQSDHQPK 277
            +  R      +   AE   T  +S P    H   P+   T        S  T    +   
Sbjct: 5251 EIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEV 5310

Query: 278  KSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPP 337
             +    G   +S + TP    P ++T           VS   ++P+ +S     P+    
Sbjct: 5311 TTLMGMGPGNVSWMTTP----PVEETSS---------VSSLMSSPAMTS-----PSPVSS 5352

Query: 338  TSASAVPVSPVPQSPIPP--LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVT 395
            TS  ++P SP+P + +P   L+   ++L    P    +   N S++   +       A T
Sbjct: 5353 TSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHT 5412

Query: 396  QASLQSIIHKFLT-AGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPR 454
            +A++    +  +T  G S     S  S  A   T       S  S   D S   S  +P 
Sbjct: 5413 EAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTS--TPN 5470

Query: 455  ISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS 514
            IS  QTN +  +P  S  P   +   S         + + +  P  A  Q     +S   
Sbjct: 5471 IS--QTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSR 5528

Query: 515  LQRSSSQRSPSPGPN 529
               S   R P+  P+
Sbjct: 5529 TSISDLDR-PTIAPD 5542



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 41/243 (16%)

Query: 322  PSTSSASGLNPTSAPPTSASA----VPVSPVPQSPIPPLL-QDPNLLRQLLPALQATLQL 376
            P  S++ G      P TS+ A    +     P S +  ++ +DP +L   +P        
Sbjct: 6742 PLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSF 6801

Query: 377  NNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT-SLISQAAQLSTQAQPSNQ 435
            ++S +     +  +T+    ++L   IH   T  P    +T SL+     L T  +P+  
Sbjct: 6802 SSSLMP----SPAMTSPPVSSTLPKTIHT--TPSPMTSLLTPSLVMTTDTLGTSPEPTTS 6855

Query: 436  SPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSA- 494
            SP +L+S         S  I T   +T  I+ +    P +S    +      G  SQS+ 
Sbjct: 6856 SPPNLSS--------TSHEILTTDEDTTAIEAM---HPSTSTAATNVETTSSGHGSQSSV 6904

Query: 495  --------TQQPVTADKQQGHEPVSPRSLQRSS--------SQRSPSPGPNHTSNSSNAS 538
                       P+      GH  VS  S+  SS        S  S +PG   TS S NAS
Sbjct: 6905 LADSEKTKATAPMDTTSTMGHTTVS-TSMSVSSETTKIKRESTYSLTPGLRETSISQNAS 6963

Query: 539  NAT 541
             +T
Sbjct: 6964 FST 6966



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 74/309 (23%), Positives = 112/309 (36%), Gaps = 42/309 (13%)

Query: 211   DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHP-TATPSTVPSSPFT 269
             + ++LL  +  ++TS+        P+     S T     I+P     TA P+   SS FT
Sbjct: 11769 ETTALLSTHPRTETSKTFPASTVFPQV----SETTASLTIRPGAETSTALPTQTTSSLFT 11824

Query: 270   L------QSDHQPKKSFDAN----------GASTLSKLPTPTSSVPAQKTERKESTSGDK 313
             L      + D  P  S   +          G  T + +PT T S+   +T    +TS   
Sbjct: 11825 LLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSA 11884

Query: 314   PVSHSCTTPSTSSA-SGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ------- 365
               S S  T + S A SGL+  S        V       SP    +  P   R        
Sbjct: 11885 ETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMT 11944

Query: 366   LLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSI---------IHKFLTAGPSAFN- 415
             L+P+   T    +    +S    + T  V   +L +             F T   S F  
Sbjct: 11945 LIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTP 12004

Query: 416   -ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPV 474
               T  +S  A  S  ++ S      +++ +S  R Y +P  STP T+T    P IST  +
Sbjct: 12005 LTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTST--FSPGISTSSI 12062

Query: 475   SSQPKVSTP 483
              S    + P
Sbjct: 12063 PSSTAATVP 12071



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 100/440 (22%), Positives = 161/440 (36%), Gaps = 67/440 (15%)

Query: 86   VRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNP-----SKTSDAPYDSADDWSEHIS 140
            V E    +S  P     +HS+L+S+ S SS  S  P     +       D  D  SE ++
Sbjct: 5921 VEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVT 5980

Query: 141  SS-GKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPK---DRDYRREVMQATA 196
            SS      ++     S+     E +   +   E N    NS  K         +    T 
Sbjct: 5981 SSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTP 6040

Query: 197  TSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRA-ETHSSSTPVQHPIKPVVH 255
                 S MED   S ++   P+      +++ DRD   P   E    ST +      V++
Sbjct: 6041 PKVTGSMMEDAIVSTSTPGSPE------TKNVDRDSTSPLTPELKEDSTAL------VMN 6088

Query: 256  PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPT----PTSSVPAQKTERKESTSG 311
             T   +TV SS            S DA  A+ +S+       PT    + ++ +    S 
Sbjct: 6089 STTESNTVFSSV-----------SLDA--ATEVSRAEVTYYDPTFMPASAQSTKSPDISP 6135

Query: 312  DKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQ 371
            +   SHS + P T S      T   P+  +++    +  S I      P+   Q     +
Sbjct: 6136 EASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSE 6195

Query: 372  ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNIT-------SLIS--- 421
             T  +NN   D+ K +    +A    SL S     +T  PS    T       SL+S   
Sbjct: 6196 TTSVMNNDLNDVLKTSPF--SAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTS 6253

Query: 422  -------QAAQLSTQAQPSNQSPMSL-----TSDASSPRSYVSPRISTPQTN----TVPI 465
                   +   + T  +P  +SP +L     TS+A++    + P I+T   N    + P 
Sbjct: 6254 VPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPN 6313

Query: 466  KPLISTPPVSSQPKVSTPVV 485
            +   +  P S   K ++ VV
Sbjct: 6314 EFYFTVSPDSDPYKATSAVV 6333



 Score = 37.4 bits (85), Expect = 0.043
 Identities = 78/336 (23%), Positives = 125/336 (37%), Gaps = 54/336 (16%)

Query: 179  NSFPKDRDYRREVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAE 238
            N  P D     +++  +  S   S M+    +  +S+ P +I   T+  +   +   R +
Sbjct: 2361 NELPSDSSSSSDLINTSIAS---STMD---VTKTASISPTSISGMTASSSPSLFSSDRPQ 2414

Query: 239  THSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV 298
              +S+T            TAT  +V S+ ++L           +N   T S LP  T + 
Sbjct: 2415 VPTSTTETN---------TATSPSVSSNTYSLDGG--------SNVGGTPSTLPPFTITH 2457

Query: 299  PAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTS---------APPTSASAVPVSPVP 349
            P + +    + S  +PV    T  ST +ASG NPTS         AP T  S    + +P
Sbjct: 2458 PVETSSALLAWS--RPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLP 2515

Query: 350  QS---PIPPLLQDPNLLRQLL-PALQATLQLNNSNVDISKINEVLTAAVTQAS--LQSII 403
                    P  +  +LL   + PA   T  L+ + V  S      +   T  S  + S  
Sbjct: 2516 AMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSP 2575

Query: 404  HKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTV 463
                T    A   TS   ++  + T+   +  +   L +D     +  +P    P T T+
Sbjct: 2576 QTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTL 2635

Query: 464  ------------PIKPLISTPPVSSQPKV--STPVV 485
                        P  PL +T P SS      STP+V
Sbjct: 2636 SGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLV 2671



 Score = 36.6 bits (83), Expect = 0.074
 Identities = 63/287 (21%), Positives = 100/287 (34%), Gaps = 50/287 (17%)

Query: 285  ASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVP 344
            +S+L+ LP  TS  P   T    S S   PV+         +   L+ +S P TS+S   
Sbjct: 9727 SSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSS--- 9783

Query: 345  VSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIH 404
                           PNL    +  + AT ++     D  KI+     AV +    S +H
Sbjct: 9784 ---------------PNLSSTSV-EIPATSEI---MTDTEKIHPSSNTAVAKVRTSSSVH 9824

Query: 405  KFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVS-PRISTPQTNTV 463
            +               S ++ L+          M +TS       + S P  S  +T  +
Sbjct: 9825 E---------------SHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFS--ETRRI 9867

Query: 464  PIKPLISTPPVSSQPKVS--------TPVVKQGPVSQSATQQPVT--ADKQQGHEPVSPR 513
            P +P  S  P   +   S        T  V  G  + + T+  +T      + H P S +
Sbjct: 9868 PTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQ 9927

Query: 514  SLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALA 560
            S              + +S  S ++  T+  Q SS  +T   T  LA
Sbjct: 9928 STMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLA 9974



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 76/366 (20%), Positives = 137/366 (37%), Gaps = 60/366 (16%)

Query: 241  SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
            +SS  V H   PV   ++ PST  S      S      S    G+ T      PTSS+ A
Sbjct: 4545 ASSAHVLHSTLPV---SSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTA 4601

Query: 301  QKTERK-----ESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPP 355
             + E        ST+    +  + +  + + A+ +     P   A+ +P +P   +  P 
Sbjct: 4602 GRKENSTLQEMNSTTESNIILSNVSVGAITEATKM---EVPSFDATFIP-TPAQSTKFPD 4657

Query: 356  LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSI--IHKFLTAGPSA 413
            +    +      P +  +  +  +    S     +  A+  ++L++       +T G + 
Sbjct: 4658 IFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAH 4717

Query: 414  FNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRIS--------TPQ----TN 461
              IT+ ++   +  +Q  P  Q       +ASSP S     ++        TPQ    ++
Sbjct: 4718 SKITTAMNNDVKDVSQTNPPFQ------DEASSPSSQAPVLVTTLPSSVAFTPQWHSTSS 4771

Query: 462  TVPIKPLISTPPVSSQPKVSTPV--VKQGPVSQSATQQPV------TADKQQGHEPV--- 510
             V +  ++++  V +  KV T +  V   P S S T   +      T D +  H  +   
Sbjct: 4772 PVSMSSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTV 4831

Query: 511  -----SPRSLQRSSSQRSPSPGPNH-------TSNSSNASNATVVPQNS-----SARSTC 553
                 +  S   S S  S  P P+        TS   + + +  +P++S        +T 
Sbjct: 4832 VTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTS 4891

Query: 554  SLTPAL 559
            SLTP L
Sbjct: 4892 SLTPKL 4897



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 84/404 (20%), Positives = 157/404 (38%), Gaps = 49/404 (12%)

Query: 241  SSSTPVQHPIK-PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVP 299
            ++ T   HP     V    T S+   SP ++  D +  K+  A G  ++    + ++  P
Sbjct: 7465 TTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTP 7524

Query: 300  AQKTERK----ESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS--------AVPVSP 347
            A    RK     ++S    +  + T+  TS A+  N   +  ++ +        A+  S 
Sbjct: 7525 ALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSR 7584

Query: 348  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 407
               S         ++    +P + A+  L  S    +K+        ++++L+S ++   
Sbjct: 7585 TSMSGPEQSTMSQDISIGTIPRISASSVLTES----AKMTITTQTGPSESTLESTLNLNT 7640

Query: 408  TAGPSAFNITSLISQAAQLSTQAQPSNQSP----------MSLTSDASSPRS---YVSPR 454
               PS     S++ Q            + P          +  TS  SSP S     SP 
Sbjct: 7641 ATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPH 7700

Query: 455  -ISTPQTNTVPIKPLISTPPVSSQPKVSTPVV----KQGPVSQSA----TQQPVTADKQQ 505
             +ST     +P  PL  T  ++S P  +T ++    + G  S S+    + + +T  K  
Sbjct: 7701 PVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDT 7760

Query: 506  GH-EPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFS 564
             H E V P +    ++  + S G  + S SS  ++++ +   S+   T  LT   A  F 
Sbjct: 7761 AHTEAVHPSTNTGGTNVATTSSG--YKSQSSVLADSSPMCTTSTMGDTSVLTSTPA--FL 7816

Query: 565  ENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNL 608
            E   + +Q    + A      LRE + + GT   +++ T L  +
Sbjct: 7817 ET--RRIQ---TELASSLTPGLRESSGSEGTSSGTKMSTVLSKV 7855



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 102/503 (20%), Positives = 177/503 (35%), Gaps = 104/503 (20%)

Query: 190  EVMQATATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDY-------RLPRAETHSS 242
            E+   T T    +  +D  + D S+  PQ  +     H            R+P+  + +S
Sbjct: 4971 EITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTS 5030

Query: 243  STPVQHPIKP--------VVHPTATPSTVP----SSPFT-------------LQSDHQPK 277
               V     P        +  P+   ST+P    SSP T             L++  +P 
Sbjct: 5031 PPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPV 5090

Query: 278  KSFDANGASTLSKLPTPTS----------SVPAQKTERKESTSGDK---PVSHSCTTPST 324
             S   N +ST  K+   +           S+  ++T  K + SG +   P      TP  
Sbjct: 5091 TSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKA 5150

Query: 325  SSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSN---- 380
            ++   +  T   P  ++++PV     S    + ++P     L P L+ T     S+    
Sbjct: 5151 TTQMVITTTVGDPAPSTSMPVHG--SSETTNIKREPTYF--LTPRLRETSTSQESSFPTD 5206

Query: 381  -------VDISKINEVLTAAVTQAS-LQSIIHKFLTAGPSAFN-------ITSLISQAAQ 425
                   V    I EV +  V  +S + +  H   T  P  F         +S+ +++A+
Sbjct: 5207 TSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAE 5266

Query: 426  LSTQAQ---PSNQSPMSLTSDASS---------------PRSYVSPRISTPQTN-----T 462
            ++   Q   P + S  +L  D S+               P S V+  +     N     T
Sbjct: 5267 MTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTT 5326

Query: 463  VPIKPLISTPPVSSQPKVS--TPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
             P++   S   + S P ++  +PV    P S  ++  PVTA          P S+  +++
Sbjct: 5327 PPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTA---------LPTSVLVTTT 5377

Query: 521  QRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAE 580
                +  P   S +S+  N + +     A    +     A H S N      G      +
Sbjct: 5378 DVLGTTSPE--SVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHK 5435

Query: 581  KQASRLREEAHNMGTIHMSEICT 603
             Q+S L +   +  T  MS   T
Sbjct: 5436 SQSSVLADSETSKATPLMSTTST 5458



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 41/186 (22%), Positives = 64/186 (34%), Gaps = 18/186 (9%)

Query: 217   PQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQP 276
             P+ + SQ +             THS   P    +      T T  T P+S    Q     
Sbjct: 11740 PEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETT 11799

Query: 277   KKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAP 336
                    GA T + LPT T+S                  S      + +S   L+PT++P
Sbjct: 11800 ASLTIRPGAETSTALPTQTTS------------------SLFTLLVTGTSRVDLSPTASP 11841

Query: 337   PTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQ 396
               SA   P+S  P +    ++    L   LL         +++    S +   ++ AV+ 
Sbjct: 11842 GVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSG 11901

Query: 397   ASLQSI 402
              S  SI
Sbjct: 11902 LSSASI 11907



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 131/623 (21%), Positives = 220/623 (35%), Gaps = 91/623 (14%)

Query: 31   SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
            S+K+ PSS       + +A   SP  + +R + SP    S S G   A +V T       
Sbjct: 760  STKTKPSSAVLSSMTLSNAAT-SP--ERVRNATSPLTHPSPS-GEETAGSVLT---LSTS 812

Query: 91   GGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNC 150
              T+ SP  N H    L S +S S +  + PS +      S+   S H+ +SG++     
Sbjct: 813  AETTDSP--NIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETS 870

Query: 151  RTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATAT---SGFASGMEDK 207
               VSQ   P+  + R +    +  +    FP    +     Q +++   S   +     
Sbjct: 871  NPSVSQ---PETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTS 927

Query: 208  HSSDASSLLPQ-------NILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATP 260
             ++   S LP+         +SQT+R    D   P++ T   ++P      P    T + 
Sbjct: 928  VTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVST 987

Query: 261  S------TVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES------ 308
            S      TV  S FT  +    + +     ++T+  L T T++ P        +      
Sbjct: 988  SATSLSATVMVSKFTSPATSSMEATSIREPSTTI--LTTETTNGPGSMAVASTNIPIGKG 1045

Query: 309  --TSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQL 366
              T G    SH     + SS + ++ T A  + + +V  S   QS        P    Q 
Sbjct: 1046 YITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPS---QSMDAAGSSTPGRTSQF 1102

Query: 367  LPALQATL-QLNNSNVDISK--INEVLTAAVT--------QASLQSIIHKFLTAGPSAFN 415
            +      +  L +  + I +   +  LT  +T          S +S     L++ PS+  
Sbjct: 1103 VDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPT 1162

Query: 416  --------------ITSLISQAAQLSTQAQPSNQSPMSL------TSDASSPRSYVSPRI 455
                           TS+I    + S    P+  S  SL      TS A    + V    
Sbjct: 1163 PKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDT 1222

Query: 456  STPQTNTVPIK---PLISTPPVS------------SQPKVSTPVVKQGPVSQSATQQPVT 500
             +P T+    +   P +ST P S            S    ST  +    V +  +  P+T
Sbjct: 1223 PSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLT 1282

Query: 501  ADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV----PQNSSARSTCSLT 556
                + H  VS   +  SS        P  T+  S     T +    P+++S+    +  
Sbjct: 1283 FPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPH 1342

Query: 557  PALAAHFSENLIKHVQGWPADHA 579
                   +EN  K     PA ++
Sbjct: 1343 SVRTLRTTENHPKTESATPAAYS 1365



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 74/346 (21%), Positives = 128/346 (36%), Gaps = 55/346 (15%)

Query: 195  TATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVV 254
            ++T G  S   D  S D   L              R+  +PR  T S+ TP      P  
Sbjct: 1093 SSTPGRTSQFVDTFSDDVYHL------------TSREITIPRDGTSSALTPQMTATHP-- 1138

Query: 255  HPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKP 314
             P+  P +  S+   + S      +     +ST S     TS +     +  E++  + P
Sbjct: 1139 -PSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMI----MDTVETSRWNMP 1193

Query: 315  VSHSCTTPSTSSASGLN-PTSAPPTSASAVPV-SPVP-------QSPIPPLLQDPNLLRQ 365
                   PST+S +  N PTS     ++ VP+ +P P       +  +P L   P     
Sbjct: 1194 -----NLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNT 1248

Query: 366  LLPALQATLQLNN-SNVDISKINEVLTAAVTQASLQSI-IHKFLTAGPSAFNITSLISQA 423
                L A     + S + ++  + V   + T  +  SI  H  ++    A++  S     
Sbjct: 1249 PSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMT 1308

Query: 424  AQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTP-------------QTNTVPIKPLIS 470
            A   T    +      +T+  + P+   S ++STP             +T +        
Sbjct: 1309 APGETNTGSTWDPTTYITT--TDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSG 1366

Query: 471  TPPVSSQPKVSTPVVKQGPV---SQSATQQPVT--ADKQQGHEPVS 511
            +P +SS P +++P  K   +   ++ +TQ   T  A+K  G E  S
Sbjct: 1367 SPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQS 1412



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 55/243 (22%), Positives = 89/243 (36%), Gaps = 20/243 (8%)

Query: 238  ETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQS----DHQPKKSFDA----NGASTLS 289
            ET++ ST           P  T S   S+P ++++    ++ PK         +G+  +S
Sbjct: 1312 ETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKIS 1371

Query: 290  KLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 349
              P  TS  PA K      T+      H   T     +SG    SAP   +  +P SP  
Sbjct: 1372 SSPNLTS--PATKAWTITDTTEHSTQLHY--TKLAEKSSGFETQSAPGPVSVVIPTSPTI 1427

Query: 350  QSPIPPLLQD-PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLT 408
             S    L  D P     L P+ Q T+ L  +    + + E + +     S  S       
Sbjct: 1428 GSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPS------- 1480

Query: 409  AGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPL 468
            +  S F I   +S  +   ++++    +  +  S        +     T    TVPI PL
Sbjct: 1481 SPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPL 1540

Query: 469  IST 471
             +T
Sbjct: 1541 TTT 1543



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 84/389 (21%), Positives = 144/389 (37%), Gaps = 55/389 (14%)

Query: 224   TSRHNDRDYRLPR-----AETHSSSTPVQHPIKPVVH--PTATPSTVPSSPFTLQSDHQP 276
             TS   DR+  +P       E  + ++ V HP        PT+T S   S   T       
Sbjct: 10742 TSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLA 10801

Query: 277   KKSFDANGASTLSK-LPTPTSSV---PAQKTERKESTSGDKPVSHSCTTPSTSSASGLNP 332
              K+   N A T S   P  T S+   PAQ +     T+     S S TTPS +++ G   
Sbjct: 10802 AKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAES 10861

Query: 333   TSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL-------QATLQLNNSNVDISK 385
             +SA PT   +   + VP    P +     ++   +P L       + T  +  S+ +  +
Sbjct: 10862 SSAVPTPTVS---TEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGE--E 10916

Query: 386   INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLI------------SQAAQLSTQAQPS 433
              +  +        +  ++   +T+  +  + T  I            S A    T+A  +
Sbjct: 10917 ASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSA 10976

Query: 434   -----NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQ--PKVSTPVVK 486
                   + P  +TS  +S R+  S  +  P     P +P  +TP +++    + S+ V  
Sbjct: 10977 VPTVLPEVPGMVTSLVASSRAVTSTTL--PTLTLSPGEP-ETTPSMATSHGAEASSTVPT 11033

Query: 487   QGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNA--------- 537
               P         VT+        +    L     + +PS   +H + +S+A         
Sbjct: 11034 VSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPG 11093

Query: 538   SNATVVPQNSSARSTCSLT-PALAAHFSE 565
              +  V P  +S+R+  S T P L    SE
Sbjct: 11094 VSGVVTPLVTSSRAVTSTTIPILTLSSSE 11122



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 73/352 (20%), Positives = 135/352 (38%), Gaps = 57/352 (16%)

Query: 257  TATPSTVPSSPFTLQSDHQP---KKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDK 313
            T TPS  P+S   + S  +P   +KS     AS++        SVPA KT   E+T G  
Sbjct: 3114 TFTPSETPTSLLPVSSPTEPTARRKSSPETWASSI--------SVPA-KTSLVETTDGTL 3164

Query: 314  PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
              +      S+ +A G +   AP     + P    P S                P +  T
Sbjct: 3165 VTT---IKMSSQAAQGNSTWPAPAEETGSSPAGTSPGS----------------PEMSTT 3205

Query: 374  LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS 433
            L++ +S      I+  + + V  +  ++      T  P    +  +  Q+  L + +   
Sbjct: 3206 LKIMSSKE--PSISPEIRSTVRNSPWKTP----ETTVPMETTVEPVTLQSTALGSGSTSI 3259

Query: 434  NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP-----LISTPPVSSQPKVST--PVVK 486
            +  P   TS   SP   +   ++T + +  P  P     L S  P  ++  ++T   V  
Sbjct: 3260 SHLPTGTTSPTKSPTENM---LATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSL 3316

Query: 487  QGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 546
            + P ++S T       +Q   E VS  +    S     + G    ++ S ++++ ++   
Sbjct: 3317 ESPTARSIT----GTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDP 3372

Query: 547  SSARSTCSLTPALAAHFSENLI------KHVQGWPADHAEKQASRLREEAHN 592
             ++ ++ S     + H +E  +        V       AE+Q SR  +EA++
Sbjct: 3373 VTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYS 3424



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 48/308 (15%)

Query: 313  KPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA 372
            +P     ++P+T+S S ++ T     S+S +PV+ +  S +        L +   P   +
Sbjct: 7969 RPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTD--MLHKSSEPVTNS 8026

Query: 373  TLQLNNSNVDISKINEVLT-AAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
               L++++V+I   +EV T    T  S    +    T+  S    TS +   +Q S    
Sbjct: 8027 PANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSS-SGHESTSFVLADSQTSKVT- 8084

Query: 432  PSNQSPMSLTS-------DASSPRSYVSPRISTPQTNTVPI-----------------KP 467
                SPM +TS         S+P  + + RI T  T+++ +                   
Sbjct: 8085 ----SPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMST 8140

Query: 468  LISTPPVSSQPKVS-TPVVKQGPVSQSA----TQQPVTADKQQGHEPVSPRSLQRSSSQ- 521
            ++S  P  +  +VS T V      S S     T  P T+ +     P S  S+   S++ 
Sbjct: 8141 VLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTS--SIMTESAEM 8198

Query: 522  --RSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQG---WPA 576
              ++ +  P  T  S++  + +  P      ST  +T   +      L+    G   WP+
Sbjct: 8199 MIKTQTDPPGSTPESTHTVDISTTPNWVETHST--VTQRFSHSEMTTLVSRSPGDMLWPS 8256

Query: 577  DHAEKQAS 584
              + ++ S
Sbjct: 8257 QSSVEETS 8264



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 8/123 (6%)

Query: 237  AETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTL---SKLPT 293
            +ET +S  PV  P +P     ++P T  SS  ++ +     ++ D    +T+   S+   
Sbjct: 3118 SETPTSLLPVSSPTEPTARRKSSPETWASS-ISVPAKTSLVETTDGTLVTTIKMSSQAAQ 3176

Query: 294  PTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSP--VPQS 351
              S+ PA   E   S +G  P S   +T  T         S  P   S V  SP   P++
Sbjct: 3177 GNSTWPAPAEETGSSPAGTSPGSPEMST--TLKIMSSKEPSISPEIRSTVRNSPWKTPET 3234

Query: 352  PIP 354
             +P
Sbjct: 3235 TVP 3237



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 54/234 (23%), Positives = 88/234 (37%), Gaps = 38/234 (16%)

Query: 256  PTAT-PSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKP 314
            PT T PST  S    L S H    S  +N +ST ++ P  +++  +   +R   T    P
Sbjct: 2060 PTTTWPSTSLSE--ALSSGH----SGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGP 2113

Query: 315  VSHSCTTPST--SSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQA 372
             + + +T +T  SS +GL+ T    + +S VP+     S            R  +  L +
Sbjct: 2114 QNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITS------------RSDVSGLTS 2161

Query: 373  TLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQP 432
                N S    S     LT  ++  + +S++   +   P   +I               P
Sbjct: 2162 ESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSI---------------P 2206

Query: 433  SNQSPMSLTSDASSPRSYVSPRISTPQTNTV--PIKPLISTPPVSSQPKVSTPV 484
                P + T  +    S   P +ST  ++ +  P     S P VS  P   T V
Sbjct: 2207 LGSHPTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEV 2260



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 69/333 (20%), Positives = 129/333 (38%), Gaps = 41/333 (12%)

Query: 257   TATPSTVPS-------SPFTLQSDHQPKKSFDANGASTLSKLPTPTSSV---PAQKTERK 306
             TA P T PS       +  +L S    ++S         S  P  T+S    PA+     
Sbjct: 10551 TALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTV 10610

Query: 307   ESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSAS---------AVPVSPVPQS-PIPPL 356
               T+ +   S   T  ST+++ G + +SA PT+ S          V +S    S   P L
Sbjct: 10611 SKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTL 10670

Query: 357   LQDPNLLRQLLPAL------QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAG 410
              + P+        L       +T+     N    + +   + A +  +  S     +T  
Sbjct: 10671 TKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVS 10730

Query: 411   PSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLIS 470
             P A ++ +     +Q+++     N +  +LT     P++ ++  ++ P+  T    P  +
Sbjct: 10731 PGAEDLVT-----SQVTSSGTDRNMTIPTLTLSPGEPKT-IASLVTHPEAQTSSAIPTST 10784

Query: 471   TPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNH 530
               P  S  ++ T +V       S T + +T       EP +  SL    +Q SP+  P  
Sbjct: 10785 ISPAVS--RLVTSMVTSLAAKTSTTNRALT---NSPGEPATTVSLVTHPAQTSPTV-PWT 10838

Query: 531   TS---NSSNASNATVVPQNSSARSTCSLTPALA 560
             TS   +S + +  ++   + +  S+   TP ++
Sbjct: 10839 TSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVS 10871


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 87/356 (24%), Positives = 135/356 (37%), Gaps = 60/356 (16%)

Query: 230  RDYRLPRAETHSSSTPVQH-----PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANG 284
            R  RLP      +  P Q      P++P+    AT S  P      +  +Q       N 
Sbjct: 1904 RPPRLPMTHFGGTFPPAQSTWGPFPVRPLSPARATNS--PKPHMVPRHSNQNSSGSQVNS 1961

Query: 285  ASTLSKLPTPTSS-----VPAQKTERKESTSGDK--------PVSHSCTTPSTSSASGLN 331
            A +L+  PT T+S     VP   T    S+   +          S++ TT  T++AS  N
Sbjct: 1962 AGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNN 2021

Query: 332  --PTSAP---PTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKI 386
              PT+A    PT+    PVS  P SP PP  Q   + R             NS +D    
Sbjct: 2022 TAPTNATYPMPTAKEHYPVSS-PSSPSPPA-QPGGVSR-------------NSPLDCGSA 2066

Query: 387  --NEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS---NQSPMSLT 441
              N+V +++  +A    ++    T  P   N +S    ++  S Q QP    +Q P    
Sbjct: 2067 SPNKVASSSEQEAGSPPVVETTNTRPP---NSSSSSGSSSAHSNQQQPPGSVSQEPRPPL 2123

Query: 442  SDASSPRSYVSPRISTPQTNTVPIK---------PLISTPPVSSQP--KVSTPVVKQGPV 490
              +  P   V   +    T++ P+          P+  TP    QP  K+ TP ++  P 
Sbjct: 2124 QQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPH 2183

Query: 491  SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 546
              +A  +   + +      +S   ++R  S  S    P+  S  S   N +V P N
Sbjct: 2184 GTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQN-SVHPAN 2238



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 85/362 (23%), Positives = 138/362 (38%), Gaps = 46/362 (12%)

Query: 195  TATSGFAS---GMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQ--HP 249
            T TS  AS   G     S  + S+  Q  ++     N     +    +++++ P    +P
Sbjct: 1971 TTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYP 2030

Query: 250  IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKEST 309
            +     PTA      SSP +     QP       G S  S L   ++S P +     E  
Sbjct: 2031 M-----PTAKEHYPVSSPSSPSPPAQP------GGVSRNSPLDCGSAS-PNKVASSSEQE 2078

Query: 310  SGDKPVSHSCTT--PSTSSASGLNPTSA----PPTSASAVPVSPVPQSPIPP---LLQDP 360
            +G  PV  +  T  P++SS+SG +   +    PP S S  P  P+ QS +PP    +  P
Sbjct: 2079 AGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVP 2138

Query: 361  NLLRQLLP-ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
             L     P A+ +T  +              T  +   +++   H     G +A +  S 
Sbjct: 2139 PLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPH-----GTTAPHKNSA 2193

Query: 420  ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 479
              Q + ++  +    + P S+ S    P +     +ST       + P  +  P++  P 
Sbjct: 2194 SVQNSSVAVLSVNHIKRPHSVPSSVQLPST-----LSTQSACQNSVHP--ANKPIA--PN 2244

Query: 480  VSTPVVKQGPVSQSATQQPVTADKQQGHEPVS----PRSLQRSSSQRSPSPGPNHTSNSS 535
             S P +  GP S      P +A    G   VS    P S+    S   P+  P H S++S
Sbjct: 2245 FSAP-LPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTS 2303

Query: 536  NA 537
             A
Sbjct: 2304 KA 2305



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 81/397 (20%), Positives = 133/397 (33%), Gaps = 64/397 (16%)

Query: 234  LPRAETHSSSTPVQHPIKPVV--HPTATPSTVPSSPF--------TLQSDHQPKKSFDAN 283
            +P   + S+   +++P+  V    P + P   P   F        T Q    P+      
Sbjct: 1854 VPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHF 1913

Query: 284  GASTLSKLPTPTSSVPAQKTERKESTSGDKP---VSHSCTTPSTSSASGLNPTSAPPTSA 340
            G  T     +     P +      +T+  KP     HS    S S  +     ++ PT+ 
Sbjct: 1914 GG-TFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTT 1972

Query: 341  SAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQ 400
            ++   S VP +        P++ RQL   +  T     + V  +  N           + 
Sbjct: 1973 TSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMP 2032

Query: 401  SIIHKFLTAGPSA-----------------------FNITSLISQAAQL-----STQAQP 432
            +    +  + PS+                         + S   Q A       +T  +P
Sbjct: 2033 TAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRP 2092

Query: 433  SNQSPMSLTSDASS----PRSYVS--PRISTPQTNTVPIKPLISTPPV--SSQPKV---S 481
             N S  S +S A S    P   VS  PR    Q+   P +  ++ PP+  SS P     +
Sbjct: 2093 PNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPST 2152

Query: 482  TPVVKQGPVSQSATQQP-----VTADKQQGHEPVSPRSLQRSSSQRSPSP-GPNHTSNSS 535
             PV    P +     QP       A +   H   +P     S    S +    NH     
Sbjct: 2153 APVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPH 2212

Query: 536  NASNATVVPQNSSARSTC--SLTPA---LAAHFSENL 567
            +  ++  +P   S +S C  S+ PA   +A +FS  L
Sbjct: 2213 SVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPL 2249



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 33/152 (21%), Positives = 56/152 (36%), Gaps = 15/152 (9%)

Query: 211  DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATP------STVP 264
            +++S+   ++   +  H  R + +P +    S+   Q   +  VHP   P      + +P
Sbjct: 2191 NSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLP 2250

Query: 265  SSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPST 324
              PF+   ++ P  +    G S +S   TP S +  +        S   P S       T
Sbjct: 2251 FGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGK--------SSYLPNSDPLHQSDT 2302

Query: 325  SSASGLN-PTSAPPTSASAVPVSPVPQSPIPP 355
            S A G   P   P  S S +     P   + P
Sbjct: 2303 SKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTP 2334


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 87/356 (24%), Positives = 135/356 (37%), Gaps = 60/356 (16%)

Query: 230  RDYRLPRAETHSSSTPVQH-----PIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANG 284
            R  RLP      +  P Q      P++P+    AT S  P      +  +Q       N 
Sbjct: 1653 RPPRLPMTHFGGTFPPAQSTWGPFPVRPLSPARATNS--PKPHMVPRHSNQNSSGSQVNS 1710

Query: 285  ASTLSKLPTPTSS-----VPAQKTERKESTSGDK--------PVSHSCTTPSTSSASGLN 331
            A +L+  PT T+S     VP   T    S+   +          S++ TT  T++AS  N
Sbjct: 1711 AGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNN 1770

Query: 332  --PTSAP---PTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKI 386
              PT+A    PT+    PVS  P SP PP  Q   + R             NS +D    
Sbjct: 1771 TAPTNATYPMPTAKEHYPVSS-PSSPSPPA-QPGGVSR-------------NSPLDCGSA 1815

Query: 387  --NEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS---NQSPMSLT 441
              N+V +++  +A    ++    T  P   N +S    ++  S Q QP    +Q P    
Sbjct: 1816 SPNKVASSSEQEAGSPPVVETTNTRPP---NSSSSSGSSSAHSNQQQPPGSVSQEPRPPL 1872

Query: 442  SDASSPRSYVSPRISTPQTNTVPIK---------PLISTPPVSSQP--KVSTPVVKQGPV 490
              +  P   V   +    T++ P+          P+  TP    QP  K+ TP ++  P 
Sbjct: 1873 QQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPH 1932

Query: 491  SQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQN 546
              +A  +   + +      +S   ++R  S  S    P+  S  S   N +V P N
Sbjct: 1933 GTTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQN-SVHPAN 1987



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 85/362 (23%), Positives = 138/362 (38%), Gaps = 46/362 (12%)

Query: 195  TATSGFAS---GMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQ--HP 249
            T TS  AS   G     S  + S+  Q  ++     N     +    +++++ P    +P
Sbjct: 1720 TTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYP 1779

Query: 250  IKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKEST 309
            +     PTA      SSP +     QP       G S  S L   ++S P +     E  
Sbjct: 1780 M-----PTAKEHYPVSSPSSPSPPAQP------GGVSRNSPLDCGSAS-PNKVASSSEQE 1827

Query: 310  SGDKPVSHSCTT--PSTSSASGLNPTSA----PPTSASAVPVSPVPQSPIPP---LLQDP 360
            +G  PV  +  T  P++SS+SG +   +    PP S S  P  P+ QS +PP    +  P
Sbjct: 1828 AGSPPVVETTNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVP 1887

Query: 361  NLLRQLLP-ALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
             L     P A+ +T  +              T  +   +++   H     G +A +  S 
Sbjct: 1888 PLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPH-----GTTAPHKNSA 1942

Query: 420  ISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPK 479
              Q + ++  +    + P S+ S    P +     +ST       + P  +  P++  P 
Sbjct: 1943 SVQNSSVAVLSVNHIKRPHSVPSSVQLPST-----LSTQSACQNSVHP--ANKPIA--PN 1993

Query: 480  VSTPVVKQGPVSQSATQQPVTADKQQGHEPVS----PRSLQRSSSQRSPSPGPNHTSNSS 535
             S P +  GP S      P +A    G   VS    P S+    S   P+  P H S++S
Sbjct: 1994 FSAP-LPFGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGKSSYLPNSDPLHQSDTS 2052

Query: 536  NA 537
             A
Sbjct: 2053 KA 2054



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 81/397 (20%), Positives = 133/397 (33%), Gaps = 64/397 (16%)

Query: 234  LPRAETHSSSTPVQHPIKPVV--HPTATPSTVPSSPF--------TLQSDHQPKKSFDAN 283
            +P   + S+   +++P+  V    P + P   P   F        T Q    P+      
Sbjct: 1603 VPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTHF 1662

Query: 284  GASTLSKLPTPTSSVPAQKTERKESTSGDKP---VSHSCTTPSTSSASGLNPTSAPPTSA 340
            G  T     +     P +      +T+  KP     HS    S S  +     ++ PT+ 
Sbjct: 1663 GG-TFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTT 1721

Query: 341  SAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQ 400
            ++   S VP +        P++ RQL   +  T     + V  +  N           + 
Sbjct: 1722 TSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPMP 1781

Query: 401  SIIHKFLTAGPSA-----------------------FNITSLISQAAQL-----STQAQP 432
            +    +  + PS+                         + S   Q A       +T  +P
Sbjct: 1782 TAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPVVETTNTRP 1841

Query: 433  SNQSPMSLTSDASS----PRSYVS--PRISTPQTNTVPIKPLISTPPV--SSQPKV---S 481
             N S  S +S A S    P   VS  PR    Q+   P +  ++ PP+  SS P     +
Sbjct: 1842 PNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPST 1901

Query: 482  TPVVKQGPVSQSATQQP-----VTADKQQGHEPVSPRSLQRSSSQRSPSP-GPNHTSNSS 535
             PV    P +     QP       A +   H   +P     S    S +    NH     
Sbjct: 1902 APVTYPMPQTPMGCPQPTPKMETPAIRPPPHGTTAPHKNSASVQNSSVAVLSVNHIKRPH 1961

Query: 536  NASNATVVPQNSSARSTC--SLTPA---LAAHFSENL 567
            +  ++  +P   S +S C  S+ PA   +A +FS  L
Sbjct: 1962 SVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPL 1998



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 33/152 (21%), Positives = 56/152 (36%), Gaps = 15/152 (9%)

Query: 211  DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPVVHPTATP------STVP 264
            +++S+   ++   +  H  R + +P +    S+   Q   +  VHP   P      + +P
Sbjct: 1940 NSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPANKPIAPNFSAPLP 1999

Query: 265  SSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPST 324
              PF+   ++ P  +    G S +S   TP S +  +        S   P S       T
Sbjct: 2000 FGPFSTLFENSPTSAHAFWGGSVVSSQSTPESMLSGK--------SSYLPNSDPLHQSDT 2051

Query: 325  SSASGLN-PTSAPPTSASAVPVSPVPQSPIPP 355
            S A G   P   P  S S +     P   + P
Sbjct: 2052 SKAPGFRPPLQRPAPSPSGIVNMDSPYGSVTP 2083


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 126/574 (21%), Positives = 206/574 (35%), Gaps = 115/574 (20%)

Query: 64   SPENKYSDSTGHSKAKNVHTHRVRERDGGTSYSPQENSHNHSAL--HSSNSHSSNPSNN- 120
            SP    S ++  S   +  +   R R G T  +   +S     L  HS+ SHSS  S + 
Sbjct: 462  SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 521

Query: 121  ----PSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKM 176
                 S T+  P  S +  + H SSSG     +  T +S          +E     +N  
Sbjct: 522  TLLPASTTTSGP--SQESTTSH-SSSG-----STDTALSPGSTTALSFGQESTTFHSNPG 573

Query: 177  AVNS--FPKDRDYRREVMQATATSGFASGMEDKHSSDAS---SLLPQNILSQTSRHNDRD 231
            + ++  FP           +T +SG        HSS  S   +L P +  S   +     
Sbjct: 574  STHTTLFP----------DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 623

Query: 232  YRLPRAETHSSSTPVQHPIKPVVHPTA---TPSTVPSSPF---TLQSDHQPKKSF----- 280
            ++   A TH++ +P      PV   T    +P + P++ F   +  S H  K +      
Sbjct: 624  FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP 683

Query: 281  DANGA--------------STLSKL--------------------------------PTP 294
            DA+G               ST S++                                PT 
Sbjct: 684  DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 743

Query: 295  TSSVPAQKTE----RKESTSGDKPVS-HSCTTPSTSSASGLNPTSAPPTSAS--AVPVSP 347
            T S PA  T      + +TS  +P S HS  +P++++  GL+  S    S+S  +   + 
Sbjct: 744  TLS-PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV 802

Query: 348  VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL 407
             P S    +  +        PA   T      +       E      + AS Q+ +   L
Sbjct: 803  FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 862

Query: 408  TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKP 467
            T        T+  S +    T+  P+  +   L  +++  R  +SP  S+ +T T+P  P
Sbjct: 863  TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR--LSP--SSTETTTLPGSP 918

Query: 468  LISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG 527
              +TP +S +    +      P S  AT  P T       E  S    Q  S+  +  P 
Sbjct: 919  --TTPSLSEK----STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD 972

Query: 528  PNHTS----------NSSNASNATVVPQNSSARS 551
               TS          +S  ++ AT+ P +++A S
Sbjct: 973  STTTSDLSQEPTTSHSSQGSTEATLSPGSTTASS 1006



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 86/398 (21%), Positives = 140/398 (35%), Gaps = 47/398 (11%)

Query: 195 TATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRD--YRLPRAETHSSSTPVQHPIKP 252
           T  SG        HSS  S     +    T+R  +    +  P ++    + P       
Sbjct: 226 TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTT--TSA 283

Query: 253 VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
            V P+ T    PSS  T     +   S     ++T    P  T ++   +++       +
Sbjct: 284 FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 343

Query: 313 KPVSHSCTT------PSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQL 366
              SHS TT      PST+SA    PTS   +S  +   +  P S       + +     
Sbjct: 344 STTSHSSTTHTISSAPSTTSALVEEPTSY-HSSPGSTATTHFPDSSTTSGRSEESTASHS 402

Query: 367 LPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQL 426
                 T+ L   +     + E  T+ ++  S+++      TA P +     L    ++ 
Sbjct: 403 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMET------TALPGSTTTPGL----SER 452

Query: 427 STQAQPSNQSPMSLTSDASSPRSYVSPRIST-------------PQTNTVPIKPLISTPP 473
           ST    S +SP +  S AS+  S VS   +T             P + T P     ST  
Sbjct: 453 STTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTS 512

Query: 474 VSSQPKVSTPVV-----KQGPVSQSATQQPVTADKQQGHEPVSPRSLQ--RSSSQRSPSP 526
            SS     T ++       GP  +S T    +        P S  +L   + S+    +P
Sbjct: 513 HSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNP 572

Query: 527 GPNHT------SNSSNASNATVVPQNSSARSTCSLTPA 558
           G  HT      + SS    A+    +S+     +L+PA
Sbjct: 573 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 610



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 77/331 (23%), Positives = 126/331 (38%), Gaps = 31/331 (9%)

Query: 240  HSSSTPVQHPIKPVVH--PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP-TPTS 296
            HS++T V        H  P +T +T+ +   T     +   +F  + AST + LP T T+
Sbjct: 805  HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 864

Query: 297  SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPT-SASAVPVSPVPQSPIPP 355
            +   +++    S+SG      S   P+ S+ SGL   S P   S S+   + +P SP  P
Sbjct: 865  ADLGEESTTFPSSSGSTGTKLS---PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 921

Query: 356  LLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN 415
             L + +           T   +  + D +     L+ A T +S  S       + P + +
Sbjct: 922  SLSEKS----------TTFYTSPRSPDAT-----LSPATTTSSGVSEESSTSHSQPGSTH 966

Query: 416  ITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVS 475
             T+        ST     +Q P +  S   S  + +SP  +T  +         S+P  +
Sbjct: 967  TTAFPD-----STTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 1021

Query: 476  SQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRS--LQRSSSQRSPSPGPNHTSN 533
                +    +  G V  S      T        P S  S  LQ  S+     P  + T+ 
Sbjct: 1022 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 1081

Query: 534  SSNASNATVVPQNSSARSTCSLTPALAAHFS 564
            S   + A  V  +++  S  S TP    HFS
Sbjct: 1082 SPPGTTAAPVEVSTTYHSRPSSTP--TTHFS 1110



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 110/545 (20%), Positives = 180/545 (33%), Gaps = 92/545 (16%)

Query: 14  GCHDRRGDSQPYQALKYSSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDST 73
           G   R+G+S  +        S PSS D R         P+PP       +        +T
Sbjct: 253 GSTTRQGESTTFH-------SWPSSKDTR---------PAPPTTTSAFVEP------STT 290

Query: 74  GHSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSAD 133
            H    ++ T  +  R   TS   +E++  HS+  S+ +     S+  S   +    S  
Sbjct: 291 SHGSPSSIPTTHISARST-TSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 349

Query: 134 DWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQ 193
             +  ISS+         T  +  E+P  +             A   FP           
Sbjct: 350 STTHTISSAPS-------TTSALVEEPTSY------HSSPGSTATTHFP----------D 386

Query: 194 ATATSGFASGMEDKHSS-DASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIKP 252
           ++ TSG +      HSS DA+  +     S TS         P +     +T +      
Sbjct: 387 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS--- 443

Query: 253 VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
               T TP     S     S   P        A+TLS   T +S V  + T  +      
Sbjct: 444 ----TTTPGLSERSTTFHSSPRSP--------ATTLSPASTTSSGVSEESTTSRSRPGST 491

Query: 313 KPVSH--SCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 370
              +   S TTP  S  S  + +S   T  + +P S     P                + 
Sbjct: 492 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP----------------SQ 535

Query: 371 QATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFL-TAGPSAFNITSLISQAAQLSTQ 429
           ++T   ++S    + ++   T A++     +  H    +   + F  ++  S   + ST+
Sbjct: 536 ESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTR 595

Query: 430 AQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGP 489
              S  SP +  S ASS     SP +    T          T P S+    S P     P
Sbjct: 596 VHSSTGSPRTTLSPASS----TSPGLQGEST-------AFQTHPASTHTTPSPPSTATAP 644

Query: 490 VSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSA 549
           V +S T           H P S  +   S         P+ +  + +++++T   +  S 
Sbjct: 645 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 704

Query: 550 RSTCS 554
            S  S
Sbjct: 705 TSRIS 709



 Score = 37.0 bits (84), Expect = 0.057
 Identities = 107/503 (21%), Positives = 167/503 (33%), Gaps = 86/503 (17%)

Query: 75   HSKAKNVHTHRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADD 134
            HS   ++HT         TS   QE S    +  SS    S+ + +P  T+ AP + +  
Sbjct: 1043 HSSTGSLHTTLTPA--SSTSAGLQEESTTFQSWPSS----SDTTPSPPGTTAAPVEVSTT 1096

Query: 135  WSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQA 194
            +    SS+   ++    T + + E      E               FP  R     ++  
Sbjct: 1097 YHSRPSSTPTTHFSASSTTLGRSE------ESTTVHSSPGATGTALFPT-RSATSVLVGE 1149

Query: 195  TATSGFASGMEDKHSSDASSL---LPQNILSQTSRHNDRDYRLPRAETHSSS----TPVQ 247
              TS  +SG  +  +   S+    L +   +  S     D  L  A T SS     +   
Sbjct: 1150 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1209

Query: 248  HPIKPVVHPTATP--STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTER 305
            H      H TA P  +T+P       + H    S D    +TLS   T  SS+  + T  
Sbjct: 1210 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD----TTLSPGSTTASSLGPESTTF 1265

Query: 306  KESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ 365
              S       + +   P  ++ASGL   S P  S++         SP   L    +  RQ
Sbjct: 1266 HSSPGS----TETTLLPDNTTASGLLEASTPVHSSTG--------SPHTTLSPAGSTTRQ 1313

Query: 366  LLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQ 425
                   T Q   S+ D        T+A  + S  S         PS+   T   + +  
Sbjct: 1314 ---GESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS------HGSPSSTPTTHFSASSTT 1364

Query: 426  L--STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTP 483
            L  S ++   + SP++  +  S  RS  S                               
Sbjct: 1365 LGRSEESTTVHSSPVATATTPSPARSTTS------------------------------- 1393

Query: 484  VVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVV 543
                G V +S          Q  H P S  +  RS   R+      HT +S  ++ + +V
Sbjct: 1394 ----GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1449

Query: 544  PQNSSARSTCSLTPALAAHFSEN 566
             + +S  S  S       HF E+
Sbjct: 1450 EEPTSYHS--SPGSIATTHFPES 1470



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 40/171 (23%), Positives = 63/171 (36%), Gaps = 20/171 (11%)

Query: 195  TATSGFASGMEDKHSSDASSLLPQNILSQTSRHNDRDYRLPRAET-HSSSTPVQHPIKPV 253
            + TSG        HSS  S+       S T+     + R   + T H+ S+P       V
Sbjct: 1390 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1449

Query: 254  VHPTATPSTVPSSPFTLQSDHQPKKSF---------------DANGASTLSKLPTPTSSV 298
              PT+      SSP ++ + H P+ S                D NG + L    T +  +
Sbjct: 1450 EEPTS----YHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 1505

Query: 299  PAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVP 349
                T      S +  ++ + TTP  S+ S +  TS      +   +SP P
Sbjct: 1506 AESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSP 1556


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 62/268 (23%), Positives = 103/268 (38%), Gaps = 38/268 (14%)

Query: 250 IKPVVHPTATP--STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKE 307
           I  V  P+A+   +T+P+  F  Q+        + N +S+++ L    S  P   T    
Sbjct: 111 IPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPP 170

Query: 308 STSGDKPVSHSCTTPSTSSASGLNP---TSAPPTSAS-----AVPVSPVPQSPIPPLLQD 359
           + S   P   S + P  ++A+   P   T APP+S++     A P +P   +P PP    
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSA 230

Query: 360 PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
           P       P   AT                     T A L S      TA P   + T+L
Sbjct: 231 PPETTAAPPTPSAT---------------------TPAPLSSSAPPETTAVPPTPSATTL 269

Query: 420 ISQAAQL---STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476
              +A     +T A P+  +       + +P+   +  I+TP ++   + P  S    + 
Sbjct: 270 DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAP 329

Query: 477 QPKVSTPVVKQGPVSQSATQQPVTADKQ 504
             + +T V  Q     + T+QP +A  Q
Sbjct: 330 THQTTTSVTTQ----TTTTKQPTSAPGQ 353



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 27/162 (16%)

Query: 241 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSS P +    P   P  TP+  PSS    ++   P               PTP+++ PA
Sbjct: 204 SSSAPPETTAAPPTPPATTPAP-PSSSAPPETTAAP---------------PTPSATTPA 247

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASG-LNPTSAPPTSAS---AVPVSPVPQSPIPPL 356
             +      +   P + S TT   SSAS     T+APPT ++   A P SP PQ      
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 357 LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQAS 398
           +  PN       +   TL  + S    +  ++  T+  TQ +
Sbjct: 308 ITTPN-------SSPTTLAPDTSETSAAPTHQTTTSVTTQTT 342



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 20/232 (8%)

Query: 332 PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT 391
           P   P  ++S V  + V  + IP +   P+   ++      T    N+    S+ N   +
Sbjct: 90  PPKHPDKNSSVVNPTLVATTQIPSVTF-PSASTKITTLPNVTFLPQNATTISSRENVNTS 148

Query: 392 AAV-TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY 450
           ++V T A + S   +  TA P   + T          T A PS+ +P   T+   +P + 
Sbjct: 149 SSVATLAPVNSPAPQDTTAAPPTPSAT----------TPAPPSSSAPPETTAAPPTPSAT 198

Query: 451 VS--PRISTP-QTNTVPIKPLIST--PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ 505
               P  S P +T   P  P  +T  PP SS P  +T      P   + T  P+++    
Sbjct: 199 TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA---PPTPSATTPAPLSSSAPP 255

Query: 506 GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
               V P     +    S S  P  T+     S  T  P +S A    +  P
Sbjct: 256 ETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 64/309 (20%), Positives = 113/309 (36%), Gaps = 21/309 (6%)

Query: 256 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS-SVPAQKTERKESTSGDKP 314
           PTA     P++P       +P  +     A T +K P+PT+   PA  T +   T+  +P
Sbjct: 350 PTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403

Query: 315 VSHSC-TTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
              +  + P+T        T  P  +    P    P+ P P   ++P       PA   T
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 374 LQ-LNNSNVDISKINEVLTAAVTQASL-QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
            +    +  + +      TA  T   L  +   K     P     T+    A     +  
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523

Query: 432 PSN-QSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP--PVSSQPKVSTPVVKQG 488
           P+  + P   T  A++P +   P  +TP+      +P  +TP  P  + PK + P   +G
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKG 577

Query: 489 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
               +  +   T  K+   + ++P + +  +S     P P  T+    A      P  ++
Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTT 635

Query: 549 ARSTCSLTP 557
            +     TP
Sbjct: 636 PKEPAPTTP 644



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 68/344 (19%), Positives = 118/344 (34%), Gaps = 20/344 (5%)

Query: 235 PRAETHSSSTPVQHPIKPV-VHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPT 293
           P+AET +    +  P +P    P    ST P  P        P    +    +T S   T
Sbjct: 199 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 258

Query: 294 PTSSVPAQKTERKESTSGDK-PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 352
           P    P    E   +T  +  P +     P+T+ ++   P    PT+    P    P+ P
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK-PAPTTPKEP 317

Query: 353 IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 412
            P   ++P       PA         +  + +       A  T         K      +
Sbjct: 318 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377

Query: 413 AFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS--------SPRSYVSPRISTPQ--TNT 462
                +   + A  +T++ P+     + T+  S        SP +   P  +TP+    T
Sbjct: 378 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 437

Query: 463 VPIKPLISTP--PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            P KP  +TP  P  + PK   P   + P   +  +   T  K+    P +P+ L  ++ 
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKKLTPTTP 495

Query: 521 QRSPSPGPNHTSNSSNASNATVVPQN---SSARSTCSLTPALAA 561
           ++     P   + ++    A   P+    ++       TP  AA
Sbjct: 496 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 539



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 66/356 (18%), Positives = 119/356 (33%), Gaps = 37/356 (10%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ-----SDHQPKKSFDANGASTLS 289
           P + T    TP      P       P+T  S+P T +     +  +P  +     A T +
Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283

Query: 290 KLPTPTSSVPAQKTERKES-TSGDKPVSHSCTTPSTSSASGLNPTS-----------APP 337
           K P PT++  A  T ++ + T+  KP   +   P+ ++     PT+           AP 
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343

Query: 338 TSASAVPVSP--------------VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDI 383
           T     P +P               P+ P P   ++P+      PA   T     +  + 
Sbjct: 344 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403

Query: 384 SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSN-QSPMSLTS 442
           +           +    +   +     P     T+    A     +  P+  + P   T+
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 443 DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTA 501
              +P +   P  +TP+  T P  P   TP   + P+   P   + P   +  +  P T 
Sbjct: 464 KKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEELAPTTP 519

Query: 502 DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
           ++     P  P      ++  +    P  T+    A      P  ++ + T   TP
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 575



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 72/356 (20%), Positives = 134/356 (37%), Gaps = 52/356 (14%)

Query: 231 DYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ--SDHQPKKSFDANGASTL 288
           D   P     ++ T  + P        A  +   ++P TL+  +   PKK      A T 
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672

Query: 289 SKLPTPTSSVPAQKTERKES----------TSGDKPVSHSCTTPSTSSASGLNPTS---- 334
           +K PT T+S     T  KE+          T+  KP   +  TP  +++    PT+    
Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732

Query: 335 -----APPTSASAVPVSPVPQ----SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK 385
                +P  S   +   P P+    SP  P +          P +  T +   +  D+  
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792

Query: 386 INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS 445
             E  TAA       +      T   +   IT+  +Q    +TQ    + +P  +T+  +
Sbjct: 793 TPETTTAAPKMTKETAT----TTEKTTESKITATTTQVTSTTTQ----DTTPFKITTLKT 844

Query: 446 SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP-------KVSTPVVK---QGPVSQSAT 495
           +    ++P+++T +  T+    +++ P  +++P       K +TP  +   + P   ++T
Sbjct: 845 TT---LAPKVTTTK-KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 900

Query: 496 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARS 551
           ++P T  + +      P++        S  P  N TS  + A   T    N +  S
Sbjct: 901 KKPKTMPRVR-----KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNS 951



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 63/335 (18%), Positives = 114/335 (34%), Gaps = 32/335 (9%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
           P      +ST    P      P  T  T P  P    +  +P  +     A T  K P P
Sbjct: 601 PTTTKEPTSTTCDKPAPTT--PKGTAPTTPKEPAPT-TPKEPAPTTPKGTAPTTLKEPAP 657

Query: 295 TS-SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP- 352
           T+   PA K     +T G    +     P+T   +       P  +    P    P++P 
Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 717

Query: 353 -------IPPLLQDPNLLRQL-------LPALQATLQLNNS----NVDISKINEVLTAAV 394
                   P   ++P  + +        L A      L NS     V  +K        +
Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 777

Query: 395 TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP- 453
           T  +      + L   P        +++    +T+    ++   + T   S+     +P 
Sbjct: 778 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 837

Query: 454 RISTPQTNTV-----PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 508
           +I+T +T T+       K  I+T  + ++P+ +     +   S++ T +P    K    +
Sbjct: 838 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KK 896

Query: 509 PVSPRSLQRSSSQRSP--SPGPNHTSNSSNASNAT 541
           P S +  +     R P  +P P   +++    N T
Sbjct: 897 PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931



 Score = 36.6 bits (83), Expect = 0.074
 Identities = 52/262 (19%), Positives = 81/262 (30%), Gaps = 29/262 (11%)

Query: 283 NGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASA 342
           N  +   K PTP   V        E+ SG        TTP TS+    N  S  P   +A
Sbjct: 69  NKKNRTKKKPTPKPPVV------DEAGSGLDNGDFKVTTPDTSTTQH-NKVSTSPKITTA 121

Query: 343 VPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKIN-EVLTAAVTQASLQS 401
            P++P P  P          L         T +   +N   S    E  T+A    S++ 
Sbjct: 122 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181

Query: 402 IIHKFL-----------------TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDA 444
              K L                 T GP+            +      P   +P ++ S  
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 241

Query: 445 SSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQ 504
           ++P+        +  T      P  +  P  + PK   P   + P   +    P T  + 
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301

Query: 505 QGHEPVSPRSLQRSSSQRSPSP 526
               P  P      ++ + P+P
Sbjct: 302 APTTPKKP----APTTPKEPAP 319


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 64/309 (20%), Positives = 113/309 (36%), Gaps = 21/309 (6%)

Query: 256 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS-SVPAQKTERKESTSGDKP 314
           PTA     P++P       +P  +     A T +K P+PT+   PA  T +   T+  +P
Sbjct: 391 PTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444

Query: 315 VSHSC-TTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
              +  + P+T        T  P  +    P    P+ P P   ++P       PA   T
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 374 LQ-LNNSNVDISKINEVLTAAVTQASL-QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
            +    +  + +      TA  T   L  +   K     P     T+    A     +  
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564

Query: 432 PSN-QSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP--PVSSQPKVSTPVVKQG 488
           P+  + P   T  A++P +   P  +TP+      +P  +TP  P  + PK + P   +G
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKG 618

Query: 489 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
               +  +   T  K+   + ++P + +  +S     P P  T+    A      P  ++
Sbjct: 619 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTT 676

Query: 549 ARSTCSLTP 557
            +     TP
Sbjct: 677 PKEPAPTTP 685



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 68/344 (19%), Positives = 118/344 (34%), Gaps = 20/344 (5%)

Query: 235 PRAETHSSSTPVQHPIKPV-VHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPT 293
           P+AET +    +  P +P    P    ST P  P        P    +    +T S   T
Sbjct: 240 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 299

Query: 294 PTSSVPAQKTERKESTSGDK-PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP 352
           P    P    E   +T  +  P +     P+T+ ++   P    PT+    P    P+ P
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK-PAPTTPKEP 358

Query: 353 IPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPS 412
            P   ++P       PA         +  + +       A  T         K      +
Sbjct: 359 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418

Query: 413 AFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS--------SPRSYVSPRISTPQ--TNT 462
                +   + A  +T++ P+     + T+  S        SP +   P  +TP+    T
Sbjct: 419 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 478

Query: 463 VPIKPLISTP--PVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSS 520
            P KP  +TP  P  + PK   P   + P   +  +   T  K+    P +P+ L  ++ 
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKKLTPTTP 536

Query: 521 QRSPSPGPNHTSNSSNASNATVVPQN---SSARSTCSLTPALAA 561
           ++     P   + ++    A   P+    ++       TP  AA
Sbjct: 537 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 580



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 66/356 (18%), Positives = 119/356 (33%), Gaps = 37/356 (10%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ-----SDHQPKKSFDANGASTLS 289
           P + T    TP      P       P+T  S+P T +     +  +P  +     A T +
Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324

Query: 290 KLPTPTSSVPAQKTERKES-TSGDKPVSHSCTTPSTSSASGLNPTS-----------APP 337
           K P PT++  A  T ++ + T+  KP   +   P+ ++     PT+           AP 
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384

Query: 338 TSASAVPVSP--------------VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDI 383
           T     P +P               P+ P P   ++P+      PA   T     +  + 
Sbjct: 385 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444

Query: 384 SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSN-QSPMSLTS 442
           +           +    +   +     P     T+    A     +  P+  + P   T+
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 443 DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTA 501
              +P +   P  +TP+  T P  P   TP   + P+   P   + P   +  +  P T 
Sbjct: 505 KKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEELAPTTP 560

Query: 502 DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
           ++     P  P      ++  +    P  T+    A      P  ++ + T   TP
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 616



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 72/356 (20%), Positives = 134/356 (37%), Gaps = 52/356 (14%)

Query: 231 DYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ--SDHQPKKSFDANGASTL 288
           D   P     ++ T  + P        A  +   ++P TL+  +   PKK      A T 
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713

Query: 289 SKLPTPTSSVPAQKTERKES----------TSGDKPVSHSCTTPSTSSASGLNPTS---- 334
           +K PT T+S     T  KE+          T+  KP   +  TP  +++    PT+    
Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773

Query: 335 -----APPTSASAVPVSPVPQ----SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK 385
                +P  S   +   P P+    SP  P +          P +  T +   +  D+  
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833

Query: 386 INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS 445
             E  TAA       +      T   +   IT+  +Q    +TQ    + +P  +T+  +
Sbjct: 834 TPETTTAAPKMTKETAT----TTEKTTESKITATTTQVTSTTTQ----DTTPFKITTLKT 885

Query: 446 SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP-------KVSTPVVK---QGPVSQSAT 495
           +    ++P+++T +  T+    +++ P  +++P       K +TP  +   + P   ++T
Sbjct: 886 TT---LAPKVTTTK-KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 941

Query: 496 QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARS 551
           ++P T  + +      P++        S  P  N TS  + A   T    N +  S
Sbjct: 942 KKPKTMPRVR-----KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNS 992



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 63/335 (18%), Positives = 114/335 (34%), Gaps = 32/335 (9%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
           P      +ST    P      P  T  T P  P    +  +P  +     A T  K P P
Sbjct: 642 PTTTKEPTSTTCDKPAPTT--PKGTAPTTPKEPAPT-TPKEPAPTTPKGTAPTTLKEPAP 698

Query: 295 TS-SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP- 352
           T+   PA K     +T G    +     P+T   +       P  +    P    P++P 
Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 758

Query: 353 -------IPPLLQDPNLLRQL-------LPALQATLQLNNS----NVDISKINEVLTAAV 394
                   P   ++P  + +        L A      L NS     V  +K        +
Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 818

Query: 395 TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP- 453
           T  +      + L   P        +++    +T+    ++   + T   S+     +P 
Sbjct: 819 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 878

Query: 454 RISTPQTNTV-----PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 508
           +I+T +T T+       K  I+T  + ++P+ +     +   S++ T +P    K    +
Sbjct: 879 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KK 937

Query: 509 PVSPRSLQRSSSQRSP--SPGPNHTSNSSNASNAT 541
           P S +  +     R P  +P P   +++    N T
Sbjct: 938 PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972



 Score = 36.6 bits (83), Expect = 0.074
 Identities = 52/262 (19%), Positives = 81/262 (30%), Gaps = 29/262 (11%)

Query: 283 NGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASA 342
           N  +   K PTP   V        E+ SG        TTP TS+    N  S  P   +A
Sbjct: 110 NKKNRTKKKPTPKPPVV------DEAGSGLDNGDFKVTTPDTSTTQH-NKVSTSPKITTA 162

Query: 343 VPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKIN-EVLTAAVTQASLQS 401
            P++P P  P          L         T +   +N   S    E  T+A    S++ 
Sbjct: 163 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 222

Query: 402 IIHKFL-----------------TAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDA 444
              K L                 T GP+            +      P   +P ++ S  
Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 282

Query: 445 SSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQ 504
           ++P+        +  T      P  +  P  + PK   P   + P   +    P T  + 
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342

Query: 505 QGHEPVSPRSLQRSSSQRSPSP 526
               P  P      ++ + P+P
Sbjct: 343 APTTPKKP----APTTPKEPAP 360


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 64/309 (20%), Positives = 113/309 (36%), Gaps = 21/309 (6%)

Query: 256 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS-SVPAQKTERKESTSGDKP 314
           PTA     P++P       +P  +     A T +K P+PT+   PA  T +   T+  +P
Sbjct: 443 PTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496

Query: 315 VSHSC-TTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
              +  + P+T        T  P  +    P    P+ P P   ++P       PA   T
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 374 LQ-LNNSNVDISKINEVLTAAVTQASL-QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
            +    +  + +      TA  T   L  +   K     P     T+    A     +  
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616

Query: 432 PSN-QSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP--PVSSQPKVSTPVVKQG 488
           P+  + P   T  A++P +   P  +TP+      +P  +TP  P  + PK + P   +G
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKG 670

Query: 489 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
               +  +   T  K+   + ++P + +  +S     P P  T+    A      P  ++
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTT 728

Query: 549 ARSTCSLTP 557
            +     TP
Sbjct: 729 PKEPAPTTP 737



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 107/565 (18%), Positives = 189/565 (33%), Gaps = 41/565 (7%)

Query: 31  SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
           S K+ P SG  +  K      P PPNK   +      + ++   HS ++N  +       
Sbjct: 75  SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEE--HSVSENQESSSSSSSS 132

Query: 91  GGTSYSPQENSHNHSALHSSNSHS---SNPSNNPSKTSDAPYDSADDWSEHISSSGKKYY 147
             +S   +  S  +SA +          +   N +K    P     D +     +G    
Sbjct: 133 SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKV 192

Query: 148 YNCRTEVSQWEK---------PKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATS 198
               T  +Q  K          K    R      ++     S   +++   E  + T T+
Sbjct: 193 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 252

Query: 199 GFAS--GMEDKHSSDASSLLPQNI---LSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPV 253
              S  G E   S+  +  + +     L+ TS+   +    P+AET +    +  P +P 
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTTPKEPT 310

Query: 254 -VHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
              P    ST P  P        P    +    +T S   TP    P    E   +T  +
Sbjct: 311 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 370

Query: 313 K-PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQ 371
             P +     P+T+ ++   P    PT+    P    P+ P P   ++P       PA  
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPTPTTPKEPAPT 429

Query: 372 ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
                  +  + +       A  T         K      +     +   + A  +T++ 
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489

Query: 432 PSNQSPMSLTSDAS--------SPRSYVSPRISTPQ--TNTVPIKPLISTP--PVSSQPK 479
           P+     + T+  S        SP +   P  +TP+    T P KP  +TP  P  + PK
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549

Query: 480 VSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASN 539
              P   + P   +  +   T  K+    P +P+ L  ++ ++     P   + ++    
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607

Query: 540 ATVVPQN---SSARSTCSLTPALAA 561
           A   P+    ++       TP  AA
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAA 632



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 66/356 (18%), Positives = 119/356 (33%), Gaps = 37/356 (10%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ-----SDHQPKKSFDANGASTLS 289
           P + T    TP      P       P+T  S+P T +     +  +P  +     A T +
Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376

Query: 290 KLPTPTSSVPAQKTERKES-TSGDKPVSHSCTTPSTSSASGLNPTS-----------APP 337
           K P PT++  A  T ++ + T+  KP   +   P+ ++     PT+           AP 
Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436

Query: 338 TSASAVPVSP--------------VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDI 383
           T     P +P               P+ P P   ++P+      PA   T     +  + 
Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496

Query: 384 SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSN-QSPMSLTS 442
           +           +    +   +     P     T+    A     +  P+  + P   T+
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 443 DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTA 501
              +P +   P  +TP+  T P  P   TP   + P+   P   + P   +  +  P T 
Sbjct: 557 KKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEELAPTTP 612

Query: 502 DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
           ++     P  P      ++  +    P  T+    A      P  ++ + T   TP
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 668



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 72/356 (20%), Positives = 134/356 (37%), Gaps = 52/356 (14%)

Query: 231  DYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ--SDHQPKKSFDANGASTL 288
            D   P     ++ T  + P        A  +   ++P TL+  +   PKK      A T 
Sbjct: 706  DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765

Query: 289  SKLPTPTSSVPAQKTERKES----------TSGDKPVSHSCTTPSTSSASGLNPTS---- 334
            +K PT T+S     T  KE+          T+  KP   +  TP  +++    PT+    
Sbjct: 766  TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825

Query: 335  -----APPTSASAVPVSPVPQ----SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK 385
                 +P  S   +   P P+    SP  P +          P +  T +   +  D+  
Sbjct: 826  TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885

Query: 386  INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS 445
              E  TAA       +      T   +   IT+  +Q    +TQ    + +P  +T+  +
Sbjct: 886  TPETTTAAPKMTKETAT----TTEKTTESKITATTTQVTSTTTQ----DTTPFKITTLKT 937

Query: 446  SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP-------KVSTPVVK---QGPVSQSAT 495
            +    ++P+++T +  T+    +++ P  +++P       K +TP  +   + P   ++T
Sbjct: 938  TT---LAPKVTTTK-KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 993

Query: 496  QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARS 551
            ++P T  + +      P++        S  P  N TS  + A   T    N +  S
Sbjct: 994  KKPKTMPRVR-----KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNS 1044



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 63/335 (18%), Positives = 114/335 (34%), Gaps = 32/335 (9%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P      +ST    P      P  T  T P  P    +  +P  +     A T  K P P
Sbjct: 694  PTTTKEPTSTTCDKPAPTT--PKGTAPTTPKEPAPT-TPKEPAPTTPKGTAPTTLKEPAP 750

Query: 295  TS-SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP- 352
            T+   PA K     +T G    +     P+T   +       P  +    P    P++P 
Sbjct: 751  TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 810

Query: 353  -------IPPLLQDPNLLRQL-------LPALQATLQLNNS----NVDISKINEVLTAAV 394
                    P   ++P  + +        L A      L NS     V  +K        +
Sbjct: 811  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 870

Query: 395  TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP- 453
            T  +      + L   P        +++    +T+    ++   + T   S+     +P 
Sbjct: 871  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 930

Query: 454  RISTPQTNTV-----PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 508
            +I+T +T T+       K  I+T  + ++P+ +     +   S++ T +P    K    +
Sbjct: 931  KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KK 989

Query: 509  PVSPRSLQRSSSQRSP--SPGPNHTSNSSNASNAT 541
            P S +  +     R P  +P P   +++    N T
Sbjct: 990  PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 57/273 (20%), Positives = 104/273 (38%), Gaps = 49/273 (17%)

Query: 317 HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQL 376
           H+ T+P +S  +       PP+ AS    S   +SP PP   +    ++++ + + T + 
Sbjct: 67  HNPTSPPSSKKA------PPPSGASQTIKSTTKRSPKPP---NKKKTKKVIESEEITEEH 117

Query: 377 NNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN----ITSLISQAAQLSTQAQP 432
           + S       N+  +++ + +S  S I K  ++  SA N        +    +  T+ +P
Sbjct: 118 SVSE------NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP 171

Query: 433 SNQSPMSLTSDASSPRSYVSPRISTPQTNTV---------------PIKPLISTPPVSSQ 477
           + + P  +  +A S       +++TP T+T                PI P  S PP S  
Sbjct: 172 TPKPP--VVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 229

Query: 478 PK-VSTPVVKQGPVSQSAT------------QQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
            K  S  V K+  V    T            ++  +A + Q  E  S + L  +S   + 
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289

Query: 525 SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
                 T+    A      P  ++ +   S TP
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 322


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 64/309 (20%), Positives = 113/309 (36%), Gaps = 21/309 (6%)

Query: 256 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTS-SVPAQKTERKESTSGDKP 314
           PTA     P++P       +P  +     A T +K P+PT+   PA  T +   T+  +P
Sbjct: 484 PTAPKKPAPTTP------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537

Query: 315 VSHSC-TTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
              +  + P+T        T  P  +    P    P+ P P   ++P       PA   T
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 374 LQ-LNNSNVDISKINEVLTAAVTQASL-QSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
            +    +  + +      TA  T   L  +   K     P     T+    A     +  
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657

Query: 432 PSN-QSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTP--PVSSQPKVSTPVVKQG 488
           P+  + P   T  A++P +   P  +TP+      +P  +TP  P  + PK + P   +G
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKEPAPTTPK------EPAPTTPKEPAPTTPKETAPTTPKG 711

Query: 489 PVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSS 548
               +  +   T  K+   + ++P + +  +S     P P  T+    A      P  ++
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP--TTPKGTAPTTPKEPAPTT 769

Query: 549 ARSTCSLTP 557
            +     TP
Sbjct: 770 PKEPAPTTP 778



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 107/565 (18%), Positives = 189/565 (33%), Gaps = 41/565 (7%)

Query: 31  SSKSHPSSGDHRHEKMRDAGDPSPPNKMLRRSDSPENKYSDSTGHSKAKNVHTHRVRERD 90
           S K+ P SG  +  K      P PPNK   +      + ++   HS ++N  +       
Sbjct: 116 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEE--HSVSENQESSSSSSSS 173

Query: 91  GGTSYSPQENSHNHSALHSSNSHS---SNPSNNPSKTSDAPYDSADDWSEHISSSGKKYY 147
             +S   +  S  +SA +          +   N +K    P     D +     +G    
Sbjct: 174 SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKV 233

Query: 148 YNCRTEVSQWEK---------PKEWLEREQRQKEANKMAVNSFPKDRDYRREVMQATATS 198
               T  +Q  K          K    R      ++     S   +++   E  + T T+
Sbjct: 234 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 293

Query: 199 GFAS--GMEDKHSSDASSLLPQNI---LSQTSRHNDRDYRLPRAETHSSSTPVQHPIKPV 253
              S  G E   S+  +  + +     L+ TS+   +    P+AET +    +  P +P 
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTTPKEPT 351

Query: 254 -VHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGD 312
              P    ST P  P        P    +    +T S   TP    P    E   +T  +
Sbjct: 352 PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE 411

Query: 313 K-PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQ 371
             P +     P+T+ ++   P    PT+    P    P+ P P   ++P       PA  
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPTPTTPKEPAPT 470

Query: 372 ATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQ 431
                  +  + +       A  T         K      +     +   + A  +T++ 
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530

Query: 432 PSNQSPMSLTSDAS--------SPRSYVSPRISTPQ--TNTVPIKPLISTP--PVSSQPK 479
           P+     + T+  S        SP +   P  +TP+    T P KP  +TP  P  + PK
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590

Query: 480 VSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASN 539
              P   + P   +  +   T  K+    P +P+ L  ++ ++     P   + ++    
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648

Query: 540 ATVVPQN---SSARSTCSLTPALAA 561
           A   P+    ++       TP  AA
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAA 673



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 66/356 (18%), Positives = 119/356 (33%), Gaps = 37/356 (10%)

Query: 235 PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ-----SDHQPKKSFDANGASTLS 289
           P + T    TP      P       P+T  S+P T +     +  +P  +     A T +
Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417

Query: 290 KLPTPTSSVPAQKTERKES-TSGDKPVSHSCTTPSTSSASGLNPTS-----------APP 337
           K P PT++  A  T ++ + T+  KP   +   P+ ++     PT+           AP 
Sbjct: 418 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477

Query: 338 TSASAVPVSP--------------VPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDI 383
           T     P +P               P+ P P   ++P+      PA   T     +  + 
Sbjct: 478 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537

Query: 384 SKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSN-QSPMSLTS 442
           +           +    +   +     P     T+    A     +  P+  + P   T+
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 443 DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQ-QPVTA 501
              +P +   P  +TP+  T P  P   TP   + P+   P   + P   +  +  P T 
Sbjct: 598 KKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEELAPTTP 653

Query: 502 DKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
           ++     P  P      ++  +    P  T+    A      P  ++ + T   TP
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 709



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 72/356 (20%), Positives = 134/356 (37%), Gaps = 52/356 (14%)

Query: 231  DYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQ--SDHQPKKSFDANGASTL 288
            D   P     ++ T  + P        A  +   ++P TL+  +   PKK      A T 
Sbjct: 747  DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806

Query: 289  SKLPTPTSSVPAQKTERKES----------TSGDKPVSHSCTTPSTSSASGLNPTS---- 334
            +K PT T+S     T  KE+          T+  KP   +  TP  +++    PT+    
Sbjct: 807  TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866

Query: 335  -----APPTSASAVPVSPVPQ----SPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISK 385
                 +P  S   +   P P+    SP  P +          P +  T +   +  D+  
Sbjct: 867  TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926

Query: 386  INEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDAS 445
              E  TAA       +      T   +   IT+  +Q    +TQ    + +P  +T+  +
Sbjct: 927  TPETTTAAPKMTKETAT----TTEKTTESKITATTTQVTSTTTQ----DTTPFKITTLKT 978

Query: 446  SPRSYVSPRISTPQTNTVPIKPLISTPPVSSQP-------KVSTPVVK---QGPVSQSAT 495
            +    ++P+++T +  T+    +++ P  +++P       K +TP  +   + P   ++T
Sbjct: 979  TT---LAPKVTTTK-KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 1034

Query: 496  QQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARS 551
            ++P T  + +      P++        S  P  N TS  + A   T    N +  S
Sbjct: 1035 KKPKTMPRVR-----KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNS 1085



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 63/335 (18%), Positives = 114/335 (34%), Gaps = 32/335 (9%)

Query: 235  PRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTP 294
            P      +ST    P      P  T  T P  P    +  +P  +     A T  K P P
Sbjct: 735  PTTTKEPTSTTCDKPAPTT--PKGTAPTTPKEPAPT-TPKEPAPTTPKGTAPTTLKEPAP 791

Query: 295  TS-SVPAQKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSP- 352
            T+   PA K     +T G    +     P+T   +       P  +    P    P++P 
Sbjct: 792  TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 851

Query: 353  -------IPPLLQDPNLLRQL-------LPALQATLQLNNS----NVDISKINEVLTAAV 394
                    P   ++P  + +        L A      L NS     V  +K        +
Sbjct: 852  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 911

Query: 395  TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSP- 453
            T  +      + L   P        +++    +T+    ++   + T   S+     +P 
Sbjct: 912  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 971

Query: 454  RISTPQTNTV-----PIKPLISTPPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQGHE 508
            +I+T +T T+       K  I+T  + ++P+ +     +   S++ T +P    K    +
Sbjct: 972  KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP-KK 1030

Query: 509  PVSPRSLQRSSSQRSP--SPGPNHTSNSSNASNAT 541
            P S +  +     R P  +P P   +++    N T
Sbjct: 1031 PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 57/273 (20%), Positives = 104/273 (38%), Gaps = 49/273 (17%)

Query: 317 HSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQL 376
           H+ T+P +S  +       PP+ AS    S   +SP PP   +    ++++ + + T + 
Sbjct: 108 HNPTSPPSSKKA------PPPSGASQTIKSTTKRSPKPP---NKKKTKKVIESEEITEEH 158

Query: 377 NNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFN----ITSLISQAAQLSTQAQP 432
           + S       N+  +++ + +S  S I K  ++  SA N        +    +  T+ +P
Sbjct: 159 SVSE------NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP 212

Query: 433 SNQSPMSLTSDASSPRSYVSPRISTPQTNTV---------------PIKPLISTPPVSSQ 477
           + + P  +  +A S       +++TP T+T                PI P  S PP S  
Sbjct: 213 TPKPP--VVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 270

Query: 478 PK-VSTPVVKQGPVSQSAT------------QQPVTADKQQGHEPVSPRSLQRSSSQRSP 524
            K  S  V K+  V    T            ++  +A + Q  E  S + L  +S   + 
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330

Query: 525 SPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
                 T+    A      P  ++ +   S TP
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTP 363


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 69/313 (22%), Positives = 126/313 (40%), Gaps = 19/313 (6%)

Query: 256 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES--TSGDK 313
           P+ TP+  PSSP TL     P  +  +    T S  PT T S P   T       T  + 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63

Query: 314 PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
           P     +TP+ + +S    T  P  + S+ P      +P  P    P+    L P+   T
Sbjct: 64  PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPT----LTPSSPPTLTPSNTPTLTPSNTPT 119

Query: 374 LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS 433
           L  +N+          LT + T  +L       LT      +  +L   +  + T++   
Sbjct: 120 LTPSNTPTLTPSSTPTLTPSST-PTLTPSSRPILTRS----STPTLTPSSRPILTRSSTP 174

Query: 434 NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPV-SQ 492
             +P S  +   S    ++P  STP T T   +P+++     +    S P++      + 
Sbjct: 175 TLTPSSTPTLTPSSTPTLTPS-STP-TLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTL 232

Query: 493 SATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS---SA 549
           + + +P+    +     ++P S    +   +P+  P++T   + ++  T+ P ++   + 
Sbjct: 233 TPSSRPILT--RSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP 290

Query: 550 RSTCSLTPALAAH 562
            ST +LTP+   H
Sbjct: 291 SSTPTLTPSSLWH 303



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 5/134 (3%)

Query: 242 SSTPVQHPIKP-VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP--TPTSSV 298
           SSTP   P  P  + P+ TP+  PS+  TL   + P  +  +    T S  P  TP+S  
Sbjct: 91  SSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRP 150

Query: 299 PAQKTERKESTSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPL 356
              ++     T   +P+    +TP  + SS   L P+S P  + S+ P       PI   
Sbjct: 151 ILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTR 210

Query: 357 LQDPNLLRQLLPAL 370
              P L     P L
Sbjct: 211 SSTPTLTPSSRPIL 224



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 11/168 (6%)

Query: 210 SDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK-PVVHPTATPSTVPSSPF 268
           S   +L PQ IL+++S         P      S+TP   P   P + P+ TP+  PSS  
Sbjct: 77  SSTPTLTPQPILTRSSTPTLTPSSPPTLTP--SNTPTLTPSNTPTLTPSNTPTLTPSSTP 134

Query: 269 TLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPST---- 324
           TL     P  +   +    L++  TPT +  ++    + ST    P S    TPS+    
Sbjct: 135 TLTPSSTP--TLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTL 192

Query: 325 --SSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 370
             SS   L P+S P  + S+ P       PI      P L     P L
Sbjct: 193 TPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPIL 240



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/136 (26%), Positives = 52/136 (38%), Gaps = 9/136 (6%)

Query: 244 TPVQHPI-----KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP--TPTS 296
           TP   PI      P + P++TP+  PSS  TL     P  +  +    T S  P  TP+S
Sbjct: 161 TPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSS 220

Query: 297 SVPAQKTERKESTSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSPIP 354
                 +     T   +P+    +TP  + SS   L P++ P  + S  P      +P  
Sbjct: 221 RPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTL 280

Query: 355 PLLQDPNLLRQLLPAL 370
                P L     P L
Sbjct: 281 TPSSTPTLTPSSTPTL 296



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 5/116 (4%)

Query: 242 SSTPVQHPIK-PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP--TPTSSV 298
           SSTP   P   P + P++TP+  PSS  TL    +P  +  +    T S  P  TP+S+ 
Sbjct: 171 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTP 230

Query: 299 PAQKTERKESTSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSP 352
               + R   T    P     +TP  + S+   L P++ P  + S  P      +P
Sbjct: 231 TLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTP 286



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 242 SSTPVQHPI-KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSTP   P  +P++  ++TP+  PSS   L     P  +   +    L++  TPT +  +
Sbjct: 195 SSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTP--TLTPSSRPILTRSSTPTLTPSS 252

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVP 344
             T    +T    P +    TPS +    L P+S P  + S+ P
Sbjct: 253 TPTLTPSNTPTLTPSNTPTLTPSNTPT--LTPSSTPTLTPSSTP 294



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 13/103 (12%)

Query: 242 SSTPVQHPI-KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSTP   P  +P++ P++TP+  PSS   L     P          TL+   TPT +   
Sbjct: 211 SSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTP----------TLTPSSTPTLTPSN 260

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAV 343
             T    +T    P +    TP  SS   L P+S P  + S++
Sbjct: 261 TPTLTPSNTPTLTPSNTPTLTP--SSTPTLTPSSTPTLTPSSL 301



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 57/258 (22%), Positives = 100/258 (38%), Gaps = 21/258 (8%)

Query: 321 TPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ----LLPALQATLQL 376
           T + S+   L P+S P  + S+ P       PI      P L       L P+   TL  
Sbjct: 1   TLTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60

Query: 377 NNSNVDISKINEVLTAAVTQA-SLQSIIHKFLT-----AGPSAFNITSLISQAAQLSTQA 430
           +N+          LT + T   + Q I+ +  T     + P     ++  +     +   
Sbjct: 61  SNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 120

Query: 431 QPSNQSPMSLTS-----DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVV 485
            PSN   ++ +S      +S+P    S R    +++T  + P  S+ P+ ++    T   
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTP--SSRPILTRSSTPTLTP 178

Query: 486 KQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR-SPSPGPNHTSNSS---NASNAT 541
              P    ++   +T        P S   L RSS+   +PS  P  T +S+     S+  
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238

Query: 542 VVPQNSSARSTCSLTPAL 559
           ++ ++S+   T S TP L
Sbjct: 239 ILTRSSTPTLTPSSTPTL 256


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 69/313 (22%), Positives = 126/313 (40%), Gaps = 19/313 (6%)

Query: 256 PTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKES--TSGDK 313
           P+ TP+  PSSP TL     P  +  +    T S  PT T S P   T       T  + 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63

Query: 314 PVSHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQAT 373
           P     +TP+ + +S    T  P  + S+ P      +P  P    P+    L P+   T
Sbjct: 64  PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPT----LTPSSPPTLTPSNTPTLTPSNTPT 119

Query: 374 LQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPS 433
           L  +N+          LT + T  +L       LT      +  +L   +  + T++   
Sbjct: 120 LTPSNTPTLTPSSTPTLTPSST-PTLTPSSRPILTRS----STPTLTPSSRPILTRSSTP 174

Query: 434 NQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVVKQGPV-SQ 492
             +P S  +   S    ++P  STP T T   +P+++     +    S P++      + 
Sbjct: 175 TLTPSSTPTLTPSSTPTLTPS-STP-TLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTL 232

Query: 493 SATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNS---SA 549
           + + +P+    +     ++P S    +   +P+  P++T   + ++  T+ P ++   + 
Sbjct: 233 TPSSRPILT--RSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTP 290

Query: 550 RSTCSLTPALAAH 562
            ST +LTP+   H
Sbjct: 291 SSTPTLTPSSLWH 303



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 5/134 (3%)

Query: 242 SSTPVQHPIKP-VVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP--TPTSSV 298
           SSTP   P  P  + P+ TP+  PS+  TL   + P  +  +    T S  P  TP+S  
Sbjct: 91  SSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRP 150

Query: 299 PAQKTERKESTSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSPIPPL 356
              ++     T   +P+    +TP  + SS   L P+S P  + S+ P       PI   
Sbjct: 151 ILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTR 210

Query: 357 LQDPNLLRQLLPAL 370
              P L     P L
Sbjct: 211 SSTPTLTPSSRPIL 224



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 11/168 (6%)

Query: 210 SDASSLLPQNILSQTSRHNDRDYRLPRAETHSSSTPVQHPIK-PVVHPTATPSTVPSSPF 268
           S   +L PQ IL+++S         P      S+TP   P   P + P+ TP+  PSS  
Sbjct: 77  SSTPTLTPQPILTRSSTPTLTPSSPPTLTP--SNTPTLTPSNTPTLTPSNTPTLTPSSTP 134

Query: 269 TLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKESTSGDKPVSHSCTTPST---- 324
           TL     P  +   +    L++  TPT +  ++    + ST    P S    TPS+    
Sbjct: 135 TLTPSSTP--TLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTL 192

Query: 325 --SSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPAL 370
             SS   L P+S P  + S+ P       PI      P L     P L
Sbjct: 193 TPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPIL 240



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/136 (26%), Positives = 52/136 (38%), Gaps = 9/136 (6%)

Query: 244 TPVQHPI-----KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP--TPTS 296
           TP   PI      P + P++TP+  PSS  TL     P  +  +    T S  P  TP+S
Sbjct: 161 TPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSS 220

Query: 297 SVPAQKTERKESTSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSPIP 354
                 +     T   +P+    +TP  + SS   L P++ P  + S  P      +P  
Sbjct: 221 RPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTL 280

Query: 355 PLLQDPNLLRQLLPAL 370
                P L     P L
Sbjct: 281 TPSSTPTLTPSSTPTL 296



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 5/116 (4%)

Query: 242 SSTPVQHPIK-PVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLP--TPTSSV 298
           SSTP   P   P + P++TP+  PSS  TL    +P  +  +    T S  P  TP+S+ 
Sbjct: 171 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTP 230

Query: 299 PAQKTERKESTSGDKPVSHSCTTP--STSSASGLNPTSAPPTSASAVPVSPVPQSP 352
               + R   T    P     +TP  + S+   L P++ P  + S  P      +P
Sbjct: 231 TLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTP 286



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 242 SSTPVQHPI-KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSTP   P  +P++  ++TP+  PSS   L     P  +   +    L++  TPT +  +
Sbjct: 195 SSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTP--TLTPSSRPILTRSSTPTLTPSS 252

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAVP 344
             T    +T    P +    TPS +    L P+S P  + S+ P
Sbjct: 253 TPTLTPSNTPTLTPSNTPTLTPSNTPT--LTPSSTPTLTPSSTP 294



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 13/103 (12%)

Query: 242 SSTPVQHPI-KPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSTP   P  +P++ P++TP+  PSS   L     P          TL+   TPT +   
Sbjct: 211 SSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTP----------TLTPSSTPTLTPSN 260

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASGLNPTSAPPTSASAV 343
             T    +T    P +    TP  SS   L P+S P  + S++
Sbjct: 261 TPTLTPSNTPTLTPSNTPTLTP--SSTPTLTPSSTPTLTPSSL 301



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 57/258 (22%), Positives = 100/258 (38%), Gaps = 21/258 (8%)

Query: 321 TPSTSSASGLNPTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQ----LLPALQATLQL 376
           T + S+   L P+S P  + S+ P       PI      P L       L P+   TL  
Sbjct: 1   TLTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60

Query: 377 NNSNVDISKINEVLTAAVTQA-SLQSIIHKFLT-----AGPSAFNITSLISQAAQLSTQA 430
           +N+          LT + T   + Q I+ +  T     + P     ++  +     +   
Sbjct: 61  SNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 120

Query: 431 QPSNQSPMSLTS-----DASSPRSYVSPRISTPQTNTVPIKPLISTPPVSSQPKVSTPVV 485
            PSN   ++ +S      +S+P    S R    +++T  + P  S+ P+ ++    T   
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTP--SSRPILTRSSTPTLTP 178

Query: 486 KQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQR-SPSPGPNHTSNSS---NASNAT 541
              P    ++   +T        P S   L RSS+   +PS  P  T +S+     S+  
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238

Query: 542 VVPQNSSARSTCSLTPAL 559
           ++ ++S+   T S TP L
Sbjct: 239 ILTRSSTPTLTPSSTPTL 256


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 62/268 (23%), Positives = 103/268 (38%), Gaps = 38/268 (14%)

Query: 250 IKPVVHPTATP--STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKE 307
           I  V  P+A+   +T+P+  F  Q+        + N +S+++ L    S  P   T    
Sbjct: 111 IPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPP 170

Query: 308 STSGDKPVSHSCTTPSTSSASGLNP---TSAPPTSAS-----AVPVSPVPQSPIPPLLQD 359
           + S   P   S + P  ++A+   P   T APP+S++     A P +P   +P PP    
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSA 230

Query: 360 PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
           P       P   AT                     T A L S      TA P   + T+L
Sbjct: 231 PPETTAAPPTPSAT---------------------TPAPLSSSAPPETTAVPPTPSATTL 269

Query: 420 ISQAAQL---STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476
              +A     +T A P+  +       + +P+   +  I+TP ++   + P  S    + 
Sbjct: 270 DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAP 329

Query: 477 QPKVSTPVVKQGPVSQSATQQPVTADKQ 504
             + +T V  Q     + T+QP +A  Q
Sbjct: 330 THQTTTSVTTQ----TTTTKQPTSAPGQ 353



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 27/162 (16%)

Query: 241 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSS P +    P   P  TP+  PSS    ++   P               PTP+++ PA
Sbjct: 204 SSSAPPETTAAPPTPPATTPAP-PSSSAPPETTAAP---------------PTPSATTPA 247

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASG-LNPTSAPPTSAS---AVPVSPVPQSPIPPL 356
             +      +   P + S TT   SSAS     T+APPT ++   A P SP PQ      
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 357 LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQAS 398
           +  PN       +   TL  + S    +  ++  T+  TQ +
Sbjct: 308 ITTPN-------SSPTTLAPDTSETSAAPTHQTTTSVTTQTT 342



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 20/232 (8%)

Query: 332 PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT 391
           P   P  ++S V  + V  + IP +   P+   ++      T    N+    S+ N   +
Sbjct: 90  PPKHPDKNSSVVNPTLVATTQIPSVTF-PSASTKITTLPNVTFLPQNATTISSRENVNTS 148

Query: 392 AAV-TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY 450
           ++V T A + S   +  TA P   + T          T A PS+ +P   T+   +P + 
Sbjct: 149 SSVATLAPVNSPAPQDTTAAPPTPSAT----------TPAPPSSSAPPETTAAPPTPSAT 198

Query: 451 VS--PRISTP-QTNTVPIKPLIST--PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ 505
               P  S P +T   P  P  +T  PP SS P  +T      P   + T  P+++    
Sbjct: 199 TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA---PPTPSATTPAPLSSSAPP 255

Query: 506 GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
               V P     +    S S  P  T+     S  T  P +S A    +  P
Sbjct: 256 ETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 62/268 (23%), Positives = 103/268 (38%), Gaps = 38/268 (14%)

Query: 250 IKPVVHPTATP--STVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPAQKTERKE 307
           I  V  P+A+   +T+P+  F  Q+        + N +S+++ L    S  P   T    
Sbjct: 111 IPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPP 170

Query: 308 STSGDKPVSHSCTTPSTSSASGLNP---TSAPPTSAS-----AVPVSPVPQSPIPPLLQD 359
           + S   P   S + P  ++A+   P   T APP+S++     A P +P   +P PP    
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSA 230

Query: 360 PNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSL 419
           P       P   AT                     T A L S      TA P   + T+L
Sbjct: 231 PPETTAAPPTPSAT---------------------TPAPLSSSAPPETTAVPPTPSATTL 269

Query: 420 ISQAAQL---STQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476
              +A     +T A P+  +       + +P+   +  I+TP ++   + P  S    + 
Sbjct: 270 DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAP 329

Query: 477 QPKVSTPVVKQGPVSQSATQQPVTADKQ 504
             + +T V  Q     + T+QP +A  Q
Sbjct: 330 THQTTTSVTTQ----TTTTKQPTSAPGQ 353



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 27/162 (16%)

Query: 241 SSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTSSVPA 300
           SSS P +    P   P  TP+  PSS    ++   P               PTP+++ PA
Sbjct: 204 SSSAPPETTAAPPTPPATTPAP-PSSSAPPETTAAP---------------PTPSATTPA 247

Query: 301 QKTERKESTSGDKPVSHSCTTPSTSSASG-LNPTSAPPTSAS---AVPVSPVPQSPIPPL 356
             +      +   P + S TT   SSAS     T+APPT ++   A P SP PQ      
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307

Query: 357 LQDPNLLRQLLPALQATLQLNNSNVDISKINEVLTAAVTQAS 398
           +  PN       +   TL  + S    +  ++  T+  TQ +
Sbjct: 308 ITTPN-------SSPTTLAPDTSETSAAPTHQTTTSVTTQTT 342



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 55/232 (23%), Positives = 87/232 (37%), Gaps = 20/232 (8%)

Query: 332 PTSAPPTSASAVPVSPVPQSPIPPLLQDPNLLRQLLPALQATLQLNNSNVDISKINEVLT 391
           P   P  ++S V  + V  + IP +   P+   ++      T    N+    S+ N   +
Sbjct: 90  PPKHPDKNSSVVNPTLVATTQIPSVTF-PSASTKITTLPNVTFLPQNATTISSRENVNTS 148

Query: 392 AAV-TQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSY 450
           ++V T A + S   +  TA P   + T          T A PS+ +P   T+   +P + 
Sbjct: 149 SSVATLAPVNSPAPQDTTAAPPTPSAT----------TPAPPSSSAPPETTAAPPTPSAT 198

Query: 451 VS--PRISTP-QTNTVPIKPLIST--PPVSSQPKVSTPVVKQGPVSQSATQQPVTADKQQ 505
               P  S P +T   P  P  +T  PP SS P  +T      P   + T  P+++    
Sbjct: 199 TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA---PPTPSATTPAPLSSSAPP 255

Query: 506 GHEPVSPRSLQRSSSQRSPSPGPNHTSNSSNASNATVVPQNSSARSTCSLTP 557
               V P     +    S S  P  T+     S  T  P +S A    +  P
Sbjct: 256 ETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAP 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.120    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,305,995
Number of Sequences: 37866
Number of extensions: 1421832
Number of successful extensions: 14846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 1071
Number of HSP's that attempted gapping in prelim test: 9355
Number of HSP's gapped (non-prelim): 4505
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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