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Search of human proteins with 18375507
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens]
(518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens] 1064 0.0
gi|18375505 APEX nuclease 1 [Homo sapiens] 83 5e-16
gi|18375503 APEX nuclease 1 [Homo sapiens] 83 5e-16
gi|18375501 APEX nuclease 1 [Homo sapiens] 83 5e-16
gi|157388969 nei endonuclease VIII-like 3 [Homo sapiens] 49 8e-06
gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens] 46 9e-05
gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens] 34 0.28
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 33 0.48
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 33 0.48
gi|218505680 exoribonuclease 2 isoform 1 [Homo sapiens] 33 0.82
gi|7019477 HtrA serine peptidase 2 isoform 1 preproprotein [Homo... 32 1.1
gi|21614538 HtrA serine peptidase 2 isoform 2 [Homo sapiens] 32 1.1
gi|38683827 ADAM metallopeptidase with thrombospondin type 1 mot... 32 1.1
gi|153792764 hypothetical protein LOC57624 [Homo sapiens] 32 1.8
gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens] 32 1.8
gi|169166423 PREDICTED: hypothetical protein [Homo sapiens] 32 1.8
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 32 1.8
gi|209862789 microtubule associated monoxygenase, calponin and L... 32 1.8
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 31 2.4
gi|188219559 protein phosphatase 1, regulatory subunit 15B [Homo... 31 2.4
gi|111955326 MLX interacting protein [Homo sapiens] 31 3.1
gi|169207534 PREDICTED: hypothetical protein [Homo sapiens] 30 5.3
gi|169207799 PREDICTED: hypothetical protein [Homo sapiens] 30 5.3
gi|5031777 isocitrate dehydrogenase 3 (NAD+) alpha precursor [Ho... 30 5.3
gi|40807471 transcription termination factor, RNA polymerase II ... 30 5.3
gi|219842266 usherin isoform B [Homo sapiens] 30 6.9
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 30 6.9
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 30 6.9
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 30 6.9
gi|22749425 spermatid associated [Homo sapiens] 30 6.9
>gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens]
Length = 518
Score = 1064 bits (2751), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MLRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPL 60
MLRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPL
Sbjct: 1 MLRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPL 60
Query: 61 AIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGNMDEFT 120
AIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGNMDEFT
Sbjct: 61 AIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGNMDEFT 120
Query: 121 QEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQI 180
QEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQI
Sbjct: 121 QEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQI 180
Query: 181 RAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHV 240
RAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHV
Sbjct: 181 RAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHV 240
Query: 241 GPFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVIDTFQASFLLPEVM 300
GPFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVIDTFQASFLLPEVM
Sbjct: 241 GPFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVIDTFQASFLLPEVM 300
Query: 301 GSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHN 360
GSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHN
Sbjct: 301 GSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHN 360
Query: 361 NQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSA 420
NQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSA
Sbjct: 361 NQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSA 420
Query: 421 LMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRT 480
LMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRT
Sbjct: 421 LMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRT 480
Query: 481 VKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWSRPS 518
VKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWSRPS
Sbjct: 481 VKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWSRPS 518
>gi|18375505 APEX nuclease 1 [Homo sapiens]
Length = 318
Score = 83.2 bits (204), Expect = 5e-16
Identities = 87/326 (26%), Positives = 130/326 (39%), Gaps = 83/326 (25%)
Query: 2 LRVVSWNINGIR-----RPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDAL 56
L++ SWN++G+R + L V + P DI+CLQETK + + L
Sbjct: 62 LKICSWNVDGLRAWIKKKGLDWVKEEAP-----------------DILCLQETKCSENKL 104
Query: 57 TEPLAIVEGYN-SYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGN 115
L + G + Y+S ++ GYSGV GL + Q YG
Sbjct: 105 PAELQELPGLSHQYWSAPSDKEGYSGV------------------GLLSRQCPLKVSYGI 146
Query: 116 MDEFTQEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFY 175
DE D EGR ++ + + L+ Y P+A G RL ++ R+
Sbjct: 147 GDE-------EHDQEGRVIVAEFD---------SFVLVTAYVPNAGRGLV-RLEYRQRWD 189
Query: 176 RLLQIRAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQ 235
+ + L A+ +++ GDLN AH ID G K N G
Sbjct: 190 EAFRKFLKGL-ASRKPLVLCGDLNVAHEEID---------LRNPKGNK------KNAGFT 233
Query: 236 SASHVG--------PFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVI 287
G P DS+R P A+T W+ + AR N G RLDY L +L +
Sbjct: 234 PQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSL-L 292
Query: 288 DTFQASFLLPEVMGSDHCPVGAVLSV 313
S + + +GSDHCP+ L++
Sbjct: 293 PALCDSKIRSKALGSDHCPITLYLAL 318
>gi|18375503 APEX nuclease 1 [Homo sapiens]
Length = 318
Score = 83.2 bits (204), Expect = 5e-16
Identities = 87/326 (26%), Positives = 130/326 (39%), Gaps = 83/326 (25%)
Query: 2 LRVVSWNINGIR-----RPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDAL 56
L++ SWN++G+R + L V + P DI+CLQETK + + L
Sbjct: 62 LKICSWNVDGLRAWIKKKGLDWVKEEAP-----------------DILCLQETKCSENKL 104
Query: 57 TEPLAIVEGYN-SYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGN 115
L + G + Y+S ++ GYSGV GL + Q YG
Sbjct: 105 PAELQELPGLSHQYWSAPSDKEGYSGV------------------GLLSRQCPLKVSYGI 146
Query: 116 MDEFTQEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFY 175
DE D EGR ++ + + L+ Y P+A G RL ++ R+
Sbjct: 147 GDE-------EHDQEGRVIVAEFD---------SFVLVTAYVPNAGRGLV-RLEYRQRWD 189
Query: 176 RLLQIRAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQ 235
+ + L A+ +++ GDLN AH ID G K N G
Sbjct: 190 EAFRKFLKGL-ASRKPLVLCGDLNVAHEEID---------LRNPKGNK------KNAGFT 233
Query: 236 SASHVG--------PFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVI 287
G P DS+R P A+T W+ + AR N G RLDY L +L +
Sbjct: 234 PQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSL-L 292
Query: 288 DTFQASFLLPEVMGSDHCPVGAVLSV 313
S + + +GSDHCP+ L++
Sbjct: 293 PALCDSKIRSKALGSDHCPITLYLAL 318
>gi|18375501 APEX nuclease 1 [Homo sapiens]
Length = 318
Score = 83.2 bits (204), Expect = 5e-16
Identities = 87/326 (26%), Positives = 130/326 (39%), Gaps = 83/326 (25%)
Query: 2 LRVVSWNINGIR-----RPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDAL 56
L++ SWN++G+R + L V + P DI+CLQETK + + L
Sbjct: 62 LKICSWNVDGLRAWIKKKGLDWVKEEAP-----------------DILCLQETKCSENKL 104
Query: 57 TEPLAIVEGYN-SYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGN 115
L + G + Y+S ++ GYSGV GL + Q YG
Sbjct: 105 PAELQELPGLSHQYWSAPSDKEGYSGV------------------GLLSRQCPLKVSYGI 146
Query: 116 MDEFTQEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFY 175
DE D EGR ++ + + L+ Y P+A G RL ++ R+
Sbjct: 147 GDE-------EHDQEGRVIVAEFD---------SFVLVTAYVPNAGRGLV-RLEYRQRWD 189
Query: 176 RLLQIRAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQ 235
+ + L A+ +++ GDLN AH ID G K N G
Sbjct: 190 EAFRKFLKGL-ASRKPLVLCGDLNVAHEEID---------LRNPKGNK------KNAGFT 233
Query: 236 SASHVG--------PFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVI 287
G P DS+R P A+T W+ + AR N G RLDY L +L +
Sbjct: 234 PQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSL-L 292
Query: 288 DTFQASFLLPEVMGSDHCPVGAVLSV 313
S + + +GSDHCP+ L++
Sbjct: 293 PALCDSKIRSKALGSDHCPITLYLAL 318
>gi|157388969 nei endonuclease VIII-like 3 [Homo sapiens]
Length = 605
Score = 49.3 bits (116), Expect = 8e-06
Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 25/142 (17%)
Query: 393 LKSYFQPSPSCPQASPDIELPSL--------PLMSALMTPKTPEEKAVAKVVKGQAKTSE 444
L FQ SP DI+ PS P ++P E + + KT++
Sbjct: 412 LDEEFQNSPPASVCLNDIQHPSKKTTNDITQPSSKVNISPTISSESKLFSPAHKKPKTAQ 471
Query: 445 --AKDEKELRTSFWKSVLA-----GPLR----TPLCGGHREPCVMRTVKKPGPNLGRRFY 493
+ + K + S L GP +P C H C++R V+K G N GR+FY
Sbjct: 472 YSSPELKSCNPGYSNSELQINMTDGPRTLNPDSPRCSKHNRLCILRVVRKDGENKGRQFY 531
Query: 494 MCARPRGPPTDPSSRCNFFLWS 515
C PR ++C FF W+
Sbjct: 532 ACPLPR------EAQCGFFEWA 547
Score = 40.4 bits (93), Expect = 0.004
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 7/52 (13%)
Query: 464 LRTPLCGGHREPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWS 515
L P C H + M+TV K GPN G+ F++C P +CNFF W+
Sbjct: 549 LSFPFCN-HGKRSTMKTVLKIGPNNGKNFFVC------PLGKEKQCNFFQWA 593
>gi|10835218 topoisomerase (DNA) III alpha [Homo sapiens]
Length = 1001
Score = 45.8 bits (107), Expect = 9e-05
Identities = 20/41 (48%), Positives = 26/41 (63%), Gaps = 6/41 (14%)
Query: 474 EPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLW 514
+P V RTV+K GPN GR+F+ CA+PR +C FF W
Sbjct: 901 QPSVTRTVQKDGPNKGRQFHTCAKPR------EQQCGFFQW 935
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 440 AKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRTVKKPGPNLGRRFYMCARPR 499
A + + K L + AG + C +E V+ TV+K GPN GR+F+ C
Sbjct: 784 ADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQE-AVLLTVRKEGPNRGRQFFKC---- 838
Query: 500 GPPTDPSSRCNFFLWS 515
CNFFLW+
Sbjct: 839 -----NGGSCNFFLWA 849
>gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]
Length = 1537
Score = 34.3 bits (77), Expect = 0.28
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
Query: 419 SALMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPL-CGGHREPCV 477
S+L PK EE+ A+ + + E+K T + +AGP P+ G E
Sbjct: 327 SSLKNPKLREEQEAAR----RRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAG 382
Query: 478 MRTVKKPGPNLGRR-------FYMCARPRGPP 502
TVKKP P+ R+ M R RG P
Sbjct: 383 AATVKKPSPSKARKKKLNKKGRKMAGRKRGRP 414
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 33.5 bits (75), Expect = 0.48
Identities = 17/47 (36%), Positives = 22/47 (46%)
Query: 381 PSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSALMTPKTP 427
P V + G + K +Q SP P +SP E+ SLP S P P
Sbjct: 1098 PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVP 1144
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 33.5 bits (75), Expect = 0.48
Identities = 19/53 (35%), Positives = 28/53 (52%)
Query: 365 VQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPL 417
++ CQ +A V S R PS+ G + + PSP+ P+AS + LP L L
Sbjct: 1495 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVL 1547
>gi|218505680 exoribonuclease 2 isoform 1 [Homo sapiens]
Length = 691
Score = 32.7 bits (73), Expect = 0.82
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 8/62 (12%)
Query: 456 WKSVLAGPLRTPLCG-GHREPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLW 514
WKS G + PLC G R ++ V GPN G+ FY C P G + C +F W
Sbjct: 587 WKS---GKMTPPLCKCGRRSKRLV--VSNNGPNHGKVFYCC--PIGKYQENRKCCGYFKW 639
Query: 515 SR 516
+
Sbjct: 640 EQ 641
>gi|7019477 HtrA serine peptidase 2 isoform 1 preproprotein [Homo
sapiens]
Length = 458
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 20/96 (20%)
Query: 420 ALMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLC----GGHREP 475
A +T TP +A V +T EA + R+ W +V G L GG P
Sbjct: 70 ACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLLLWGGGRGPP 129
Query: 476 CVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNF 511
V+ V P PP P S+ NF
Sbjct: 130 AVLAAVPSP----------------PPASPRSQYNF 149
>gi|21614538 HtrA serine peptidase 2 isoform 2 [Homo sapiens]
Length = 361
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 20/96 (20%)
Query: 420 ALMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLC----GGHREP 475
A +T TP +A V +T EA + R+ W +V G L GG P
Sbjct: 70 ACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLLLWGGGRGPP 129
Query: 476 CVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNF 511
V+ V P PP P S+ NF
Sbjct: 130 AVLAAVPSP----------------PPASPRSQYNF 149
>gi|38683827 ADAM metallopeptidase with thrombospondin type 1 motif, 7
preproprotein [Homo sapiens]
Length = 1686
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Query: 376 STRPQPSQVG------SSRGQKNLKSYFQPSPSCPQASPDIELPSL--PLMS--ALMTPK 425
S P PSQ G S + N F P P +PD+ LPSL P +S L TP
Sbjct: 1129 SPSPWPSQAGRSPPPPSEQTPGNPLINFLPEEDTPIGAPDLGLPSLSWPRVSTDGLQTPA 1188
Query: 426 TPEEK 430
TPE +
Sbjct: 1189 TPESQ 1193
>gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
Length = 653
Score = 31.6 bits (70), Expect = 1.8
Identities = 29/114 (25%), Positives = 42/114 (36%), Gaps = 11/114 (9%)
Query: 306 PVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHNNQTRV 365
PV +S PA P +P A + + L P +P L S + R
Sbjct: 364 PVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRT 423
Query: 366 QTCQNKAQVRSTRPQPSQVGSSRGQKNLK-----------SYFQPSPSCPQASP 408
Q+ + ST P P +G S +LK S + SPS P ++P
Sbjct: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP 477
>gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
Length = 669
Score = 31.6 bits (70), Expect = 1.8
Identities = 29/114 (25%), Positives = 42/114 (36%), Gaps = 11/114 (9%)
Query: 306 PVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHNNQTRV 365
PV +S PA P +P A + + L P +P L S + R
Sbjct: 364 PVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRT 423
Query: 366 QTCQNKAQVRSTRPQPSQVGSSRGQKNLK-----------SYFQPSPSCPQASP 408
Q+ + ST P P +G S +LK S + SPS P ++P
Sbjct: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP 477
>gi|169166423 PREDICTED: hypothetical protein [Homo sapiens]
Length = 286
Score = 31.6 bits (70), Expect = 1.8
Identities = 41/162 (25%), Positives = 62/162 (38%), Gaps = 29/162 (17%)
Query: 279 VLGDRTLVIDTFQASFLLPEVMGSDHCPVGAVLSVSSVPAKQ-CPPLCTRFLPEFAGTQL 337
+LG R V T Q +P V + P V VP Q P L T +P
Sbjct: 6 LLGTRASVCRTPQ----IPHVPCAQGTPSLQTPQVPRVPCAQGTPSLQTPQVPR------ 55
Query: 338 KILRFLVPLEQSPVLEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYF 397
VP Q +LQ RV Q +++ PQ +V ++G +L++
Sbjct: 56 ------VPCAQGT----PSLQTPQVPRVPCAQGTPSLQT--PQVPRVPCAQGTPSLQTPQ 103
Query: 398 QPSPSCPQASPDIELPSLPLMSA------LMTPKTPEEKAVA 433
P C Q +P ++ P +P + L TP+ P + A
Sbjct: 104 VPRVPCAQGTPSLQTPQVPRVPCAQGTPPLQTPQVPRDTVPA 145
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 31.6 bits (70), Expect = 1.8
Identities = 38/130 (29%), Positives = 51/130 (39%), Gaps = 20/130 (15%)
Query: 335 TQLKILRFLVPLEQSPVLEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLK 394
+QL IL L ++SP E T QH+ V + VR P + S
Sbjct: 4871 SQLDILSLLK--QESPAPEPPT-QHSYTYNV----SNLDVRQLSAPPPEEPSPP-----P 4918
Query: 395 SYFQPSPSCPQASPDIELPSLPLM-----SALMTPKTPEEKAVAKVVKGQAKTSEAKDEK 449
S PSP+ P P +ELP+ PL S L +PE A+ E +D +
Sbjct: 4919 SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPES---ARPKPRARPPEEGEDSR 4975
Query: 450 ELRTSFWKSV 459
R WK V
Sbjct: 4976 PPRLKKWKGV 4985
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 31.6 bits (70), Expect = 1.8
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 14/133 (10%)
Query: 379 PQPSQVGSSRGQKNLKSYFQPSPSC----PQASPDIELPSLPLMSALMTPKTPEEKAVAK 434
P+ + G S+ ++S P S P SP E P LP + A K+PEE+ +
Sbjct: 1144 PKHQERGPSQATSPIRS---PQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPE 1200
Query: 435 --VVKGQAKTSEAKDEKELRTSFWKSVLAGP-LRTPLCGGHREPCVMRTVKKPGPNLGRR 491
+ K + K D K + + + P RTP+ G +P P P+
Sbjct: 1201 PLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPS---P 1257
Query: 492 FYMCARPRGPPTD 504
+C++P+ P T+
Sbjct: 1258 LPICSQPQ-PSTE 1269
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 31.2 bits (69), Expect = 2.4
Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 11/106 (10%)
Query: 304 HCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHNNQT 363
H VG+ +S S Q P + +F ++ L PL+QSP +Q Q Q
Sbjct: 3434 HGMVGSEISSSRTSVSQIPFYSSDLPCDF-------MQPLGPLQQSPQHQQQMGQVLQQQ 3486
Query: 364 RVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPD 409
+Q + + S Q + R Q S+ SPS P SP+
Sbjct: 3487 NIQ----QGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPN 3528
>gi|188219559 protein phosphatase 1, regulatory subunit 15B [Homo
sapiens]
Length = 713
Score = 31.2 bits (69), Expect = 2.4
Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 295 LLPE--VMGSDHCPVGAVLSVSSVPA--KQCPPLCTRFLPEFAGTQLKILRFL 343
L PE + DHC LS +PA + CPPL T LPE ++K L FL
Sbjct: 253 LTPESSCLREDHCHPQP-LSAELIPASWQGCPPLSTEGLPEIHHLRMKRLEFL 304
>gi|111955326 MLX interacting protein [Homo sapiens]
Length = 919
Score = 30.8 bits (68), Expect = 3.1
Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 25/153 (16%)
Query: 287 IDTFQASFLLPEVMGSDHCPVGAVLSVSS---VPAKQCPPLCTRFLPEFAGTQLKILRFL 343
+DTF+ ++ S G++L S+ VP PP LP A + + L
Sbjct: 326 MDTFEP---FQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSL 382
Query: 344 VPLEQSPVLEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYF------ 397
+ +P +L H ++ Q C++ ++ QP+ G S ++ F
Sbjct: 383 IAPPTAP-----SLAHMDE---QGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTM 434
Query: 398 ---QPSPSCPQASPDIELPSLPLMSALMTPKTP 427
PSP+ P SP LP +P + + P P
Sbjct: 435 PLLSPSPAPPPISP--VLPLVPPPATALNPPAP 465
>gi|169207534 PREDICTED: hypothetical protein [Homo sapiens]
Length = 183
Score = 30.0 bits (66), Expect = 5.3
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 398 QPSPSCPQASPDIELPSLPLMS 419
+P PSCP ASPD P++P S
Sbjct: 73 RPRPSCPLASPDRRRPAIPRAS 94
>gi|169207799 PREDICTED: hypothetical protein [Homo sapiens]
Length = 140
Score = 30.0 bits (66), Expect = 5.3
Identities = 16/35 (45%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 402 SCPQASPDIELPSLPLMSALM-TPKTPEEKAVAKV 435
SCP+ASPD PS PL S + P +P A V
Sbjct: 65 SCPRASPDRPRPSCPLASPIADVPPSPARPRTAHV 99
>gi|5031777 isocitrate dehydrogenase 3 (NAD+) alpha precursor [Homo
sapiens]
Length = 366
Score = 30.0 bits (66), Expect = 5.3
Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 7/68 (10%)
Query: 408 PDIELPSLPLMSALMTPKTPEEKAVAKVVKGQAK---TSEAKDEKELRTSFWKSVLAGPL 464
P+I + + A P EE+ V + K SEAK+ + K L GPL
Sbjct: 44 PEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKN----KMGLKGPL 99
Query: 465 RTPLCGGH 472
+TP+ GH
Sbjct: 100 KTPIAAGH 107
>gi|40807471 transcription termination factor, RNA polymerase II
[Homo sapiens]
Length = 1162
Score = 30.0 bits (66), Expect = 5.3
Identities = 11/27 (40%), Positives = 16/27 (59%)
Query: 469 CGGHREPCVMRTVKKPGPNLGRRFYMC 495
C H C ++T + GPN G+ FY+C
Sbjct: 6 CPEHGTFCFLKTGVRDGPNKGKSFYVC 32
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 29.6 bits (65), Expect = 6.9
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 24/156 (15%)
Query: 142 TWEGKEKTLTLINVYCPHADPGRPERLVFK--MRFYRLLQIRA----EALLAAGSHVIIL 195
+W +K +I YC + D RL++ Y + + + LL+A +HV
Sbjct: 2074 SWNPPKKANGIITQYCLYMDG----RLIYSGSEENYTVTDLAVFTPHQFLLSACTHVGCT 2129
Query: 196 GD----LNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHVGPFIDSYRCFQ 251
L TA P +H D+ P +DS ++ + + ++ Y +
Sbjct: 2130 NSSWVLLYTAQLPPEHVDS---------PVLTVLDSRTIHIQWKQPRKISGILERYVLYM 2180
Query: 252 PKQEGAFTCWSAVTGARHLNYGSRLDYVL-GDRTLV 286
FT WS + + L L YVL G++ L+
Sbjct: 2181 SNHTHDFTIWSVIYNSTELFQDHMLQYVLPGNKYLI 2216
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 29.6 bits (65), Expect = 6.9
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 352 LEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIE 411
L+Q L +NNQ + + VR++ Q SQ S K + PSP + P
Sbjct: 1399 LQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPS---VPTKLHCPPSPHL-ENPPKSS 1454
Query: 412 LPSLPLMSALMTPKTPEEK 430
P P+ ++PK P ++
Sbjct: 1455 TPHTPVQHGYLSPKPPSQQ 1473
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 29.6 bits (65), Expect = 6.9
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 352 LEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIE 411
L+Q L +NNQ + + VR++ Q SQ S K + PSP + P
Sbjct: 1399 LQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPS---VPTKLHCPPSPHL-ENPPKSS 1454
Query: 412 LPSLPLMSALMTPKTPEEK 430
P P+ ++PK P ++
Sbjct: 1455 TPHTPVQHGYLSPKPPSQQ 1473
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 29.6 bits (65), Expect = 6.9
Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 346 LEQSPVLEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSS-RGQKNLKSYFQPSPSCP 404
L + P E S+ + + + R T + PQP+ V + + + S + P P
Sbjct: 2402 LSKIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIESDPVTP 2461
Query: 405 QASPDIELPSLPLMSA 420
+ P I +P+LP ++A
Sbjct: 2462 PSDPSIPIPTLPSVTA 2477
>gi|22749425 spermatid associated [Homo sapiens]
Length = 448
Score = 29.6 bits (65), Expect = 6.9
Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 11/108 (10%)
Query: 399 PSPSCPQASPDIELPSLPLMSALMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKS 458
PSP + S +E+ + AL P+ E+ + + + + ++K+ ++W
Sbjct: 215 PSPLLHKDSASLEVVKKDHV-ALQVPRGKEDSTLQLLREENRALQQLLEQKQ---AYWAQ 270
Query: 459 V--LAGPLRT--PLCGGHREPCVMRTVKKPGPNLGRRFYMCARPRGPP 502
A P P H EPC ++ G L RF P+GPP
Sbjct: 271 AEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRF---EEPKGPP 315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,108,419
Number of Sequences: 37866
Number of extensions: 1078146
Number of successful extensions: 3062
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3010
Number of HSP's gapped (non-prelim): 64
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.