Guide to the Human Genome
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Name: APEX1 Sequence: fasta or formatted (318aa) NCBI GI: 18375503
Description:

APEX nuclease 1

Referenced in:

DNases, Recombination, and DNA Repair

Other entries for this name:
alt mRNA [318aa] APEX nuclease 1
alt mRNA [318aa] APEX nuclease 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         27           2
 C cysteine            2.2          7           1
 D aspartate           6.0         19           1
 E glutamate           7.5         24           2
 F phenylalanine       2.8          9           1
 G glycine             7.9         25           1
 H histidine           1.9          6           1
 I isoleucine          2.5          8           1
 K lysine              9.1         29           3
 L leucine            11.6         37           2
 M methionine          0.9          3           2
 N asparagine          3.5         11           1
 P proline             6.6         21           2
 Q glutamine           3.1         10           1
 R arginine            5.3         17           1
 S serine              6.3         20           1
 T threonine           3.5         11           1
 V valine              4.7         15           1
 W tryptophan          2.2          7           1
 Y tyrosine            3.8         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   APEX nuclease 1 
APEX1                 1.000   APEX nuclease 1 
APEX1                 1.000   APEX nuclease 1 
APEX2                 0.091   apurinic/apyrimidinic endonuclease 2 
DBX1                  0.014   developing brain homeobox 1 
VPS41                 0.011   vacuolar protein sorting 41 isoform 2 
VPS41                 0.011   vacuolar protein sorting 41 isoform 1 
SCHIP1                0.009   schwannomin interacting protein 1 
TCEAL6                0.009   transcription elongation factor A (SII)-like 6 [Hom...
RYBP                  0.009   RING1 and YY1 binding protein 
TCEAL3                0.009   transcription elongation factor A (SII)-like 3 [Homo...
TCEAL3                0.009   transcription elongation factor A (SII)-like 3 [Homo...
CACNA1D               0.006   calcium channel, voltage-dependent, L type, alpha 1...
CACNA1D               0.006   calcium channel, voltage-dependent, L type, alpha 1...
CACNA1D               0.006   calcium channel, voltage-dependent, L type, alpha 1D ...
BASP1                 0.006   brain abundant, membrane attached signal protein 1 [...
TREX1                 0.006   three prime repair exonuclease 1 isoform b 
TREX1                 0.006   three prime repair exonuclease 1 isoform a 
C20orf151             0.006   hypothetical protein LOC140893 
DMP1                  0.006   dentin matrix acidic phosphoprotein 1 isoform 1 precu...
DMP1                  0.006   dentin matrix acidic phosphoprotein 1 isoform 2 pre...
TCEAL5                0.006   transcription elongation factor A (SII)-like 5 [Homo...
ATP1A1                0.005   Na+/K+ -ATPase alpha 1 subunit isoform c 
CYLC2                 0.005   cylicin 2 
ATP1A1                0.005   Na+/K+ -ATPase alpha 1 subunit isoform a 
PLEKHG4               0.005   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.005   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.005   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.005   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.005   pleckstrin homology domain containing, family G (wit...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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