BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|183603931 protein phosphatase 6, catalytic subunit isoform c [Homo sapiens] (283 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 598 e-171 gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 585 e-167 gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 567 e-162 gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 359 2e-99 gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 328 2e-90 gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 328 2e-90 gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 324 5e-89 gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 229 3e-60 gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 229 3e-60 gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 227 8e-60 gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 224 9e-59 gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 224 9e-59 gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 212 3e-55 gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 196 2e-50 gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 194 7e-50 gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 194 7e-50 gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 179 3e-45 gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 179 3e-45 gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 176 2e-44 gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 175 5e-44 gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 174 6e-44 gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 174 6e-44 gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 174 6e-44 gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 170 1e-42 gi|23312374 protein phosphatase with EF hand calcium-binding dom... 104 8e-23 gi|23312380 protein phosphatase with EF hand calcium-binding dom... 95 8e-20 gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 82 4e-16 gi|23312378 protein phosphatase with EF hand calcium-binding dom... 67 2e-11 gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 30 2.4 gi|112789546 lymphocyte-specific protein tyrosine kinase precurs... 30 2.4 >gi|183603931 protein phosphatase 6, catalytic subunit isoform c [Homo sapiens] Length = 283 Score = 598 bits (1542), Expect = e-171 Identities = 283/283 (100%), Positives = 283/283 (100%) Query: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDF 60 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDF Sbjct: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDF 60 Query: 61 VDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC 120 VDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC Sbjct: 61 VDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC 120 Query: 121 TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDV 180 TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDV Sbjct: 121 TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDV 180 Query: 181 DTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYC 240 DTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYC Sbjct: 181 DTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYC 240 Query: 241 YRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 283 YRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL Sbjct: 241 YRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 283 >gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo sapiens] Length = 305 Score = 585 bits (1509), Expect = e-167 Identities = 283/305 (92%), Positives = 283/305 (92%), Gaps = 22/305 (7%) Query: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--- 57 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ Sbjct: 1 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 60 Query: 58 -------------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 98 GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT Sbjct: 61 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 120 Query: 99 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 158 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE Sbjct: 121 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 180 Query: 159 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 218 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV Sbjct: 181 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 240 Query: 219 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 278 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT Sbjct: 241 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 300 Query: 279 TPYFL 283 TPYFL Sbjct: 301 TPYFL 305 >gi|183603929 protein phosphatase 6, catalytic subunit isoform a [Homo sapiens] Length = 342 Score = 567 bits (1461), Expect = e-162 Identities = 283/342 (82%), Positives = 283/342 (82%), Gaps = 59/342 (17%) Query: 1 MAPLDLDKYVEIARLCKYLPENDLK----------------------------------- 25 MAPLDLDKYVEIARLCKYLPENDLK Sbjct: 1 MAPLDLDKYVEIARLCKYLPENDLKVSPICGLAPSGCGAPAGRPFLSPGPPPVFHFLRFL 60 Query: 26 --RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFV 61 RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ GDFV Sbjct: 61 KERLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV 120 Query: 62 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 121 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT Sbjct: 121 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 180 Query: 122 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 181 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD Sbjct: 181 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 240 Query: 182 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 241 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY Sbjct: 241 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 300 Query: 242 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 283 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL Sbjct: 301 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 342 >gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] Length = 307 Score = 359 bits (921), Expect = 2e-99 Identities = 170/302 (56%), Positives = 217/302 (71%), Gaps = 23/302 (7%) Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57 DLD+ +E R C+ + E+++K LC ++L+EESNVQ V +PVTVCGDIHGQ Sbjct: 6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65 Query: 58 ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102 GDFVDRG+YS+ETF LLALK ++PDRITL+RGNHESRQITQVYG Sbjct: 66 FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125 Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162 FYDEC KYG+ WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE Sbjct: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185 Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222 +PH G CDL+WSDPED W +SPRGAG+LFG+ V +F N++ +ICRAHQLV EGY Sbjct: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245 Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 281 K+ F+E ++TVWSAPNYCYRCGN+A+I+ + ++ +F A P R IP + Y Sbjct: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305 Query: 282 FL 283 FL Sbjct: 306 FL 307 >gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform [Homo sapiens] Length = 309 Score = 328 bits (842), Expect = 2e-90 Identities = 161/301 (53%), Positives = 198/301 (65%), Gaps = 22/301 (7%) Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57 +LD++VE CK L EN ++ LC+ ++L +ESNVQ V PVTVCGD+HGQ Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68 Query: 58 ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102 GD+VDRGYYS+ET T L+ALK ++P+RIT+LRGNHESRQITQVYG Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128 Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162 FYDEC KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188 Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222 +PH+G CDL+WSDP+D W ISPRGAG+ FG ++ F H N L L+ RAHQLV EGY Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248 Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 282 + D +VT++SAPNYCYRCGN A+IM D F P R T YF Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308 Query: 283 L 283 L Sbjct: 309 L 309 >gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform [Homo sapiens] Length = 309 Score = 328 bits (842), Expect = 2e-90 Identities = 161/301 (53%), Positives = 198/301 (65%), Gaps = 22/301 (7%) Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57 +LD++VE CK L EN ++ LC+ ++L +ESNVQ V PVTVCGD+HGQ Sbjct: 9 ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68 Query: 58 ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102 GD+VDRGYYS+ET T L+ALK ++P+RIT+LRGNHESRQITQVYG Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128 Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162 FYDEC KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188 Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222 +PH+G CDL+WSDP+D W ISPRGAG+ FG ++ F H N L L+ RAHQLV EGY Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248 Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 282 + D +VT++SAPNYCYRCGN A+IM D F P R T YF Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308 Query: 283 L 283 L Sbjct: 309 L 309 >gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform [Homo sapiens] Length = 309 Score = 324 bits (831), Expect = 5e-89 Identities = 159/301 (52%), Positives = 197/301 (65%), Gaps = 22/301 (7%) Query: 5 DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57 +LD+++E CK L E+ +K LC+ ++L +ESNVQ V PVTVCGD+HGQ Sbjct: 9 ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68 Query: 58 ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102 GD+VDRGYYS+ET T L+ALK ++ +RIT+LRGNHESRQITQVYG Sbjct: 69 FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG 128 Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162 FYDEC KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188 Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222 +PH+G CDL+WSDP+D W ISPRGAG+ FG ++ F H N L L+ RAHQLV EGY Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248 Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 282 + D +VT++SAPNYCYRCGN A+IM D F P R T YF Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308 Query: 283 L 283 L Sbjct: 309 L 309 >gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform 3 [Homo sapiens] Length = 341 Score = 229 bits (583), Expect = 3e-60 Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 L EN+++ LC ++ L + + + P+ +CGDIHGQ Sbjct: 41 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 100 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N Sbjct: 101 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 159 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD Sbjct: 160 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 219 Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235 P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S Sbjct: 220 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 279 Query: 236 APNYCYRCGNIASIM 250 APNYC N ++M Sbjct: 280 APNYCGEFDNAGAMM 294 >gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform 1 [Homo sapiens] Length = 330 Score = 229 bits (583), Expect = 3e-60 Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 L EN+++ LC ++ L + + + P+ +CGDIHGQ Sbjct: 30 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208 Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235 P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S Sbjct: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268 Query: 236 APNYCYRCGNIASIM 250 APNYC N ++M Sbjct: 269 APNYCGEFDNAGAMM 283 >gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform [Homo sapiens] Length = 323 Score = 227 bits (579), Expect = 8e-60 Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 L EN+++ LC ++ L + + + P+ +CGDIHGQ Sbjct: 30 LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ +Y N Sbjct: 90 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P +G CDL+WSD Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208 Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235 P+ DV W + RG + FGA+V +F+H ++L LICRAHQ+V +GY+F +LVT++S Sbjct: 209 PDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268 Query: 236 APNYCYRCGNIASIM 250 APNYC N ++M Sbjct: 269 APNYCGEFDNAGAMM 283 >gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform 1 [Homo sapiens] Length = 327 Score = 224 bits (570), Expect = 9e-59 Identities = 115/296 (38%), Positives = 168/296 (56%), Gaps = 35/296 (11%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 + E +++ LC ++ L + + + P+ +CGDIHGQ Sbjct: 29 MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N Sbjct: 89 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSD Sbjct: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207 Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235 P+ DV W + RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++S Sbjct: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267 Query: 236 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 280 APNYC N + S + K + + + V PPRT P Sbjct: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323 >gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1 [Homo sapiens] Length = 327 Score = 224 bits (570), Expect = 9e-59 Identities = 115/296 (38%), Positives = 168/296 (56%), Gaps = 35/296 (11%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 + E +++ LC ++ L + + + P+ +CGDIHGQ Sbjct: 29 MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRG SLET LLA K K+P+ LLRGNHE I ++YGFYDEC+ ++ N Sbjct: 89 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 W+ T F+ L +AA++DE+I C HGGLSPD+++++QIR I R ++P G CDL+WSD Sbjct: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207 Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235 P+ DV W + RG + FGA V ++F++ ++L LICRAHQ+V +GY+F +LVT++S Sbjct: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267 Query: 236 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 280 APNYC N + S + K + + + V PPRT P Sbjct: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323 >gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform 2 [Homo sapiens] Length = 286 Score = 212 bits (539), Expect = 3e-55 Identities = 104/222 (46%), Positives = 142/222 (63%), Gaps = 24/222 (10%) Query: 52 GDIHGQ----------------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLR 89 GDIHGQ GD+VDRG SLET LLA K K+P+ LLR Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78 Query: 90 GNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIK 149 GNHE I ++YGFYDEC+ +Y N W+ T F+ L +AA++DE+I C HGGLSPD++ Sbjct: 79 GNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 137 Query: 150 TLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAISPRGAGWLFGAKVTNEFVHINNL 208 +++QIR I R ++P +G CDL+WSDP+ DV W + RG + FGA+V +F+H ++L Sbjct: 138 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDL 197 Query: 209 KLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIM 250 LICRAHQ+V +GY+F +LVT++SAPNYC N ++M Sbjct: 198 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMM 239 >gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 384 Score = 196 bits (498), Expect = 2e-50 Identities = 103/229 (44%), Positives = 134/229 (58%), Gaps = 33/229 (14%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78 L +K LC ++L EESN Q V PVTV GD HGQGD++DRGYYS+E LLA+K Sbjct: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 231 Query: 79 AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138 + + +T+L NHESRQITQVY Y+EC K+GNAN D Q+ Sbjct: 232 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 274 Query: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198 C+HGGLSP + TL IRT+ Q+IPH+G DL++SDP+D DT Sbjct: 275 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 318 Query: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIA 247 F H + L+L+ RAHQLV G+ + D +V ++S PNYCY CG +A Sbjct: 319 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCGGMA 367 >gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 254 Score = 194 bits (493), Expect = 7e-50 Identities = 102/226 (45%), Positives = 132/226 (58%), Gaps = 33/226 (14%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78 L +K LC ++L EESN Q V PVTV GD HGQGD++DRGYYS+E LLA+K Sbjct: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 110 Query: 79 AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138 + + +T+L NHESRQITQVY Y+EC K+GNAN D Q+ Sbjct: 111 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 153 Query: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198 C+HGGLSP + TL IRT+ Q+IPH+G DL++SDP+D DT Sbjct: 154 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 197 Query: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 244 F H + L+L+ RAHQLV G+ + D +V ++S PNYCY CG Sbjct: 198 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243 >gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 254 Score = 194 bits (493), Expect = 7e-50 Identities = 102/226 (45%), Positives = 132/226 (58%), Gaps = 33/226 (14%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78 L +K LC ++L EESN Q V PVTV GD HGQGD++DRGYYS+E LLA+K Sbjct: 51 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 110 Query: 79 AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138 + + +T+L NHESRQITQVY Y+EC K+GNAN D Q+ Sbjct: 111 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 153 Query: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198 C+HGGLSP + TL IRT+ Q+IPH+G DL++SDP+D DT Sbjct: 154 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 197 Query: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 244 F H + L+L+ RAHQLV G+ + D +V ++S PNYCY CG Sbjct: 198 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243 >gi|194688147 protein phosphatase 3, catalytic subunit, alpha isoform isoform 2 [Homo sapiens] Length = 511 Score = 179 bits (453), Expect = 3e-45 Identities = 106/285 (37%), Positives = 149/285 (52%), Gaps = 38/285 (13%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 L E+ R+ +L +E N+ + PVTVCGDIHGQ Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 + C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234 Query: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228 P ED + RG + + EF+ NNL I RAH+ GY+ Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 Query: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP 267 + L+T++SAPNY N A+++ +++ N + F P Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 338 >gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform isoform 1 [Homo sapiens] Length = 521 Score = 179 bits (453), Expect = 3e-45 Identities = 106/285 (37%), Positives = 149/285 (52%), Gaps = 38/285 (13%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 L E+ R+ +L +E N+ + PVTVCGDIHGQ Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 + C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234 Query: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228 P ED + RG + + EF+ NNL I RAH+ GY+ Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 Query: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP 267 + L+T++SAPNY N A+++ +++ N + F P Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 338 >gi|194688149 protein phosphatase 3, catalytic subunit, alpha isoform isoform 3 [Homo sapiens] Length = 469 Score = 176 bits (446), Expect = 2e-44 Identities = 104/274 (37%), Positives = 143/274 (52%), Gaps = 37/274 (13%) Query: 19 LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57 L E+ R+ +L +E N+ + PVTVCGDIHGQ Sbjct: 56 LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115 Query: 58 -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116 GD+VDRGY+S+E YL ALK +P + LLRGNHE R +T+ + F EC+ KY Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174 Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176 + C FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P G CD++WSD Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234 Query: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228 P ED + RG + + EF+ NNL I RAH+ GY+ Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294 Query: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVN 256 + L+T++SAPNY N + M+ +N Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328 >gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] Length = 499 Score = 175 bits (443), Expect = 5e-44 Identities = 102/245 (41%), Positives = 137/245 (55%), Gaps = 26/245 (10%) Query: 48 VTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKWPDR 84 +TVCGD HGQ GDFVDRG +S+E L K +PD Sbjct: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 Query: 85 ITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGL 144 LLRGNHE+ + Q+YGF E + KY A + ++VF+ L +A I+ ++L +HGGL Sbjct: 297 FHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355 Query: 145 -SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV 203 S D TLD IR IERN++ P G CDL+WSDP+ + +IS RG FG VT F+ Sbjct: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFL 415 Query: 204 HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKL 262 NNL I R+H++ EGY+ + VTV+SAPNYC + GN AS + + + R + Sbjct: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQ 475 Query: 263 FRAVP 267 F AVP Sbjct: 476 FTAVP 480 >gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform c [Homo sapiens] Length = 515 Score = 174 bits (442), Expect = 6e-44 Identities = 102/270 (37%), Positives = 142/270 (52%), Gaps = 38/270 (14%) Query: 34 LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71 +L E + V P+TVCGDIHGQ GD+VDRGY+S+E Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139 Query: 72 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131 YL LK +P + LLRGNHE R +T+ + F EC+ KY + C + FD L +AA Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RVYEACMEAFDSLPLAA 198 Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185 L+++Q LCVHGGLSP+I TLD IR ++R +E P G CDL+WSDP ED Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258 Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237 + RG + + EF+ NNL I RAH+ GY+ + L+T++SAP Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318 Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267 NY N A+++ +++ N + F P Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347 >gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform a [Homo sapiens] Length = 525 Score = 174 bits (442), Expect = 6e-44 Identities = 102/270 (37%), Positives = 142/270 (52%), Gaps = 38/270 (14%) Query: 34 LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71 +L E + V P+TVCGDIHGQ GD+VDRGY+S+E Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139 Query: 72 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131 YL LK +P + LLRGNHE R +T+ + F EC+ KY + C + FD L +AA Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RVYEACMEAFDSLPLAA 198 Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185 L+++Q LCVHGGLSP+I TLD IR ++R +E P G CDL+WSDP ED Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258 Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237 + RG + + EF+ NNL I RAH+ GY+ + L+T++SAP Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318 Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267 NY N A+++ +++ N + F P Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347 >gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform b [Homo sapiens] Length = 524 Score = 174 bits (442), Expect = 6e-44 Identities = 102/270 (37%), Positives = 142/270 (52%), Gaps = 38/270 (14%) Query: 34 LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71 +L E + V P+TVCGDIHGQ GD+VDRGY+S+E Sbjct: 80 ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139 Query: 72 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131 YL LK +P + LLRGNHE R +T+ + F EC+ KY + C + FD L +AA Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RVYEACMEAFDSLPLAA 198 Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185 L+++Q LCVHGGLSP+I TLD IR ++R +E P G CDL+WSDP ED Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258 Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237 + RG + + EF+ NNL I RAH+ GY+ + L+T++SAP Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318 Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267 NY N A+++ +++ N + F P Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347 >gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo sapiens] Length = 512 Score = 170 bits (430), Expect = 1e-42 Identities = 100/270 (37%), Positives = 141/270 (52%), Gaps = 38/270 (14%) Query: 34 LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71 +L +E + V P+TVCGDIHGQ GD+VDRGY+S+E Sbjct: 67 ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126 Query: 72 TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131 YL +LK P + LLRGNHE R +T + F EC+ KY + C + FD L +AA Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSE-QVYDACMETFDCLPLAA 185 Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185 L+++Q LCVHGG+SP+I +LD IR ++R E P G CDL+WSDP ED Sbjct: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245 Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237 + RG + + EF+ NNL I RAH+ GY+ + L+T++SAP Sbjct: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305 Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267 NY N A+++ +++ N + F P Sbjct: 306 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 334 >gi|23312374 protein phosphatase with EF hand calcium-binding domain 1 isoform 1b [Homo sapiens] Length = 625 Score = 104 bits (260), Expect = 8e-23 Identities = 72/237 (30%), Positives = 111/237 (46%), Gaps = 43/237 (18%) Query: 45 STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81 S VT+CGD+HG+ GDFVDRG S+E L + Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223 Query: 82 PDRITLLRGNHESRQITQVYGFYDECQTKYG--NANAWRYCTKVFDMLTVAALIDEQILC 139 P+ + L RGNHE + YGF E KY + + + L + ++D +IL Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283 Query: 140 VHGGLSPDIKTLDQIRTIERNQE----IP------------HKGAFCDLVWSDPEDVD-T 182 +HGG+S + L+ + +ERN+ IP D++WSDP + Sbjct: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGC 342 Query: 183 WAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNY 239 + + RG G FG VT++ ++ LK++ R+H+ EGY+ D K+VT++SA NY Sbjct: 343 FPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 399 >gi|23312380 protein phosphatase with EF hand calcium-binding domain 1 isoform 1 [Homo sapiens] Length = 653 Score = 94.7 bits (234), Expect = 8e-20 Identities = 72/265 (27%), Positives = 112/265 (42%), Gaps = 71/265 (26%) Query: 45 STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81 S VT+CGD+HG+ GDFVDRG S+E L + Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223 Query: 82 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 139 P+ + L RGNHE + YGF E KY + + + L + ++D +IL Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283 Query: 140 VHGGLSPDIKTLDQIRTIERNQ--------------------------------EIPHKG 167 +HGG+S + L+ + +ERN+ I G Sbjct: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNG 342 Query: 168 A------------FCDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 214 + D++WSDP + + + RG G FG VT++ ++ LK++ R+ Sbjct: 343 SPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRS 402 Query: 215 HQLVHEGYKFMFDEKLVTVWSAPNY 239 H+ EGY+ D K+VT++SA NY Sbjct: 403 HECKPEGYEICHDGKVVTIFSASNY 427 >gi|23312386 serine/threonine protein phosphatase with EF-hand motifs 2 [Homo sapiens] Length = 753 Score = 82.4 bits (202), Expect = 4e-16 Identities = 61/168 (36%), Positives = 77/168 (45%), Gaps = 37/168 (22%) Query: 30 YVCDLLLEES-------NVQPVST----PVTVCGDIHGQ--------------------- 57 YV +LL E N+ VST +TVCGD+HGQ Sbjct: 145 YVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYV 204 Query: 58 --GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKY--GN 113 GDFVDRG S+E L A +P L RGNHE + YGF E KY Sbjct: 205 FNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHG 264 Query: 114 ANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQ 161 R VF L +A LIDE++L +HGG+S DI L+ + IER++ Sbjct: 265 KEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSK 311 Score = 54.3 bits (129), Expect = 1e-07 Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Query: 171 DLVWSDPEDVDTW-AISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK 229 D++WSDP + A + RG G FG VT + + N++ + R+H+ EGY+F + K Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502 Query: 230 LVTVWSAPNYCYRCGN 245 ++T++SA NY Y G+ Sbjct: 503 VLTIFSASNY-YEVGS 517 >gi|23312378 protein phosphatase with EF hand calcium-binding domain 1 isoform 3 [Homo sapiens] Length = 591 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 26/142 (18%) Query: 45 STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81 S VT+CGD+HG+ GDFVDRG S+E L + Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223 Query: 82 PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 139 P+ + L RGNHE + YGF E KY + + + L + ++D +IL Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283 Query: 140 VHGGLSPDIKTLDQIRTIERNQ 161 +HGG+S + L+ + +ERN+ Sbjct: 284 IHGGIS-ETTDLNLLHRVERNK 304 >gi|112789548 lymphocyte-specific protein tyrosine kinase precursor [Homo sapiens] Length = 509 Score = 30.0 bits (66), Expect = 2.4 Identities = 18/67 (26%), Positives = 28/67 (41%) Query: 138 LCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAK 197 + V LS I R IE N+ +GA + W+ PE ++ + + W FG Sbjct: 370 ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429 Query: 198 VTNEFVH 204 +T H Sbjct: 430 LTEIVTH 436 >gi|112789546 lymphocyte-specific protein tyrosine kinase precursor [Homo sapiens] Length = 509 Score = 30.0 bits (66), Expect = 2.4 Identities = 18/67 (26%), Positives = 28/67 (41%) Query: 138 LCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAK 197 + V LS I R IE N+ +GA + W+ PE ++ + + W FG Sbjct: 370 ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429 Query: 198 VTNEFVH 204 +T H Sbjct: 430 LTEIVTH 436 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.140 0.453 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,715,934 Number of Sequences: 37866 Number of extensions: 516757 Number of successful extensions: 979 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 876 Number of HSP's gapped (non-prelim): 37 length of query: 283 length of database: 18,247,518 effective HSP length: 101 effective length of query: 182 effective length of database: 14,423,052 effective search space: 2624995464 effective search space used: 2624995464 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.