Guide to the Human Genome
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Search of human proteins with 183603931

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|183603931 protein phosphatase 6, catalytic subunit isoform c
[Homo sapiens]
         (283 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|183603931 protein phosphatase 6, catalytic subunit isoform c ...   598   e-171
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H...   585   e-167
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ...   567   e-162
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]    359   2e-99
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo...   328   2e-90
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor...   328   2e-90
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo...   324   5e-89
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof...   229   3e-60
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo...   229   3e-60
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo...   227   8e-60
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo...   224   9e-59
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor...   224   9e-59
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof...   212   3e-55
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly...   196   2e-50
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly...   194   7e-50
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly...   194   7e-50
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso...   179   3e-45
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo...   179   3e-45
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso...   176   2e-44
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]    175   5e-44
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof...   174   6e-44
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof...   174   6e-44
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo...   174   6e-44
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom...   170   1e-42
gi|23312374 protein phosphatase with EF hand calcium-binding dom...   104   8e-23
gi|23312380 protein phosphatase with EF hand calcium-binding dom...    95   8e-20
gi|23312386 serine/threonine protein phosphatase with EF-hand mo...    82   4e-16
gi|23312378 protein phosphatase with EF hand calcium-binding dom...    67   2e-11
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...    30   2.4  
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs...    30   2.4  

>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
           [Homo sapiens]
          Length = 283

 Score =  598 bits (1542), Expect = e-171
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 1   MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDF 60
           MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDF
Sbjct: 1   MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDF 60

Query: 61  VDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC 120
           VDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC
Sbjct: 61  VDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYC 120

Query: 121 TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDV 180
           TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDV
Sbjct: 121 TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDV 180

Query: 181 DTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYC 240
           DTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYC
Sbjct: 181 DTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYC 240

Query: 241 YRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 283
           YRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL
Sbjct: 241 YRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 283


>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
           sapiens]
          Length = 305

 Score =  585 bits (1509), Expect = e-167
 Identities = 283/305 (92%), Positives = 283/305 (92%), Gaps = 22/305 (7%)

Query: 1   MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--- 57
           MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ   
Sbjct: 1   MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 60

Query: 58  -------------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 98
                              GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT
Sbjct: 61  LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 120

Query: 99  QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 158
           QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE
Sbjct: 121 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 180

Query: 159 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 218
           RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV
Sbjct: 181 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 240

Query: 219 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 278
           HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT
Sbjct: 241 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 300

Query: 279 TPYFL 283
           TPYFL
Sbjct: 301 TPYFL 305


>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
           [Homo sapiens]
          Length = 342

 Score =  567 bits (1461), Expect = e-162
 Identities = 283/342 (82%), Positives = 283/342 (82%), Gaps = 59/342 (17%)

Query: 1   MAPLDLDKYVEIARLCKYLPENDLK----------------------------------- 25
           MAPLDLDKYVEIARLCKYLPENDLK                                   
Sbjct: 1   MAPLDLDKYVEIARLCKYLPENDLKVSPICGLAPSGCGAPAGRPFLSPGPPPVFHFLRFL 60

Query: 26  --RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFV 61
             RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ                      GDFV
Sbjct: 61  KERLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV 120

Query: 62  DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 121
           DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT
Sbjct: 121 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 180

Query: 122 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 181
           KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD
Sbjct: 181 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 240

Query: 182 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 241
           TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY
Sbjct: 241 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 300

Query: 242 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 283
           RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL
Sbjct: 301 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 342


>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
          Length = 307

 Score =  359 bits (921), Expect = 2e-99
 Identities = 170/302 (56%), Positives = 217/302 (71%), Gaps = 23/302 (7%)

Query: 5   DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57
           DLD+ +E  R C+ + E+++K LC    ++L+EESNVQ V +PVTVCGDIHGQ       
Sbjct: 6   DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65

Query: 58  ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102
                          GDFVDRG+YS+ETF  LLALK ++PDRITL+RGNHESRQITQVYG
Sbjct: 66  FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125

Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162
           FYDEC  KYG+   WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE
Sbjct: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185

Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222
           +PH G  CDL+WSDPED   W +SPRGAG+LFG+ V  +F   N++ +ICRAHQLV EGY
Sbjct: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245

Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 281
           K+ F+E ++TVWSAPNYCYRCGN+A+I+   +   ++  +F A P   R IP  +    Y
Sbjct: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305

Query: 282 FL 283
           FL
Sbjct: 306 FL 307


>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  328 bits (842), Expect = 2e-90
 Identities = 161/301 (53%), Positives = 198/301 (65%), Gaps = 22/301 (7%)

Query: 5   DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57
           +LD++VE    CK L EN ++ LC+   ++L +ESNVQ V  PVTVCGD+HGQ       
Sbjct: 9   ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68

Query: 58  ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102
                          GD+VDRGYYS+ET T L+ALK ++P+RIT+LRGNHESRQITQVYG
Sbjct: 69  FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128

Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162
           FYDEC  KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188

Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222
           +PH+G  CDL+WSDP+D   W ISPRGAG+ FG  ++  F H N L L+ RAHQLV EGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248

Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 282
            +  D  +VT++SAPNYCYRCGN A+IM   D        F   P        R T  YF
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308

Query: 283 L 283
           L
Sbjct: 309 L 309


>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  328 bits (842), Expect = 2e-90
 Identities = 161/301 (53%), Positives = 198/301 (65%), Gaps = 22/301 (7%)

Query: 5   DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57
           +LD++VE    CK L EN ++ LC+   ++L +ESNVQ V  PVTVCGD+HGQ       
Sbjct: 9   ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68

Query: 58  ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102
                          GD+VDRGYYS+ET T L+ALK ++P+RIT+LRGNHESRQITQVYG
Sbjct: 69  FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128

Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162
           FYDEC  KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188

Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222
           +PH+G  CDL+WSDP+D   W ISPRGAG+ FG  ++  F H N L L+ RAHQLV EGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248

Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 282
            +  D  +VT++SAPNYCYRCGN A+IM   D        F   P        R T  YF
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308

Query: 283 L 283
           L
Sbjct: 309 L 309


>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
           [Homo sapiens]
          Length = 309

 Score =  324 bits (831), Expect = 5e-89
 Identities = 159/301 (52%), Positives = 197/301 (65%), Gaps = 22/301 (7%)

Query: 5   DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57
           +LD+++E    CK L E+ +K LC+   ++L +ESNVQ V  PVTVCGD+HGQ       
Sbjct: 9   ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68

Query: 58  ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102
                          GD+VDRGYYS+ET T L+ALK ++ +RIT+LRGNHESRQITQVYG
Sbjct: 69  FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG 128

Query: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162
           FYDEC  KYGNAN W+Y T +FD L + AL+D QI C+HGGLSP I TLD IR ++R QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188

Query: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222
           +PH+G  CDL+WSDP+D   W ISPRGAG+ FG  ++  F H N L L+ RAHQLV EGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248

Query: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYF 282
            +  D  +VT++SAPNYCYRCGN A+IM   D        F   P        R T  YF
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYF 308

Query: 283 L 283
           L
Sbjct: 309 L 309


>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
           3 [Homo sapiens]
          Length = 341

 Score =  229 bits (583), Expect = 3e-60
 Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           L EN+++ LC    ++ L +  +  +  P+ +CGDIHGQ                     
Sbjct: 41  LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 100

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRG  SLET   LLA K K+P+   LLRGNHE   I ++YGFYDEC+ +Y N   
Sbjct: 101 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 159

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           W+  T  F+ L +AA++DE+I C HGGLSPD+++++QIR I R  ++P +G  CDL+WSD
Sbjct: 160 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 219

Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
           P+ DV  W  + RG  + FGA+V  +F+H ++L LICRAHQ+V +GY+F    +LVT++S
Sbjct: 220 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 279

Query: 236 APNYCYRCGNIASIM 250
           APNYC    N  ++M
Sbjct: 280 APNYCGEFDNAGAMM 294


>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
           1 [Homo sapiens]
          Length = 330

 Score =  229 bits (583), Expect = 3e-60
 Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           L EN+++ LC    ++ L +  +  +  P+ +CGDIHGQ                     
Sbjct: 30  LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRG  SLET   LLA K K+P+   LLRGNHE   I ++YGFYDEC+ +Y N   
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           W+  T  F+ L +AA++DE+I C HGGLSPD+++++QIR I R  ++P +G  CDL+WSD
Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208

Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
           P+ DV  W  + RG  + FGA+V  +F+H ++L LICRAHQ+V +GY+F    +LVT++S
Sbjct: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268

Query: 236 APNYCYRCGNIASIM 250
           APNYC    N  ++M
Sbjct: 269 APNYCGEFDNAGAMM 283


>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
           [Homo sapiens]
          Length = 323

 Score =  227 bits (579), Expect = 8e-60
 Identities = 112/255 (43%), Positives = 160/255 (62%), Gaps = 24/255 (9%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           L EN+++ LC    ++ L +  +  +  P+ +CGDIHGQ                     
Sbjct: 30  LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRG  SLET   LLA K K+P+   LLRGNHE   I ++YGFYDEC+ +Y N   
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           W+  T  F+ L +AA++DE+I C HGGLSPD+++++QIR I R  ++P +G  CDL+WSD
Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208

Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
           P+ DV  W  + RG  + FGA+V  +F+H ++L LICRAHQ+V +GY+F    +LVT++S
Sbjct: 209 PDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268

Query: 236 APNYCYRCGNIASIM 250
           APNYC    N  ++M
Sbjct: 269 APNYCGEFDNAGAMM 283


>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
           1 [Homo sapiens]
          Length = 327

 Score =  224 bits (570), Expect = 9e-59
 Identities = 115/296 (38%), Positives = 168/296 (56%), Gaps = 35/296 (11%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           + E +++ LC    ++ L +  +  +  P+ +CGDIHGQ                     
Sbjct: 29  MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRG  SLET   LLA K K+P+   LLRGNHE   I ++YGFYDEC+ ++ N   
Sbjct: 89  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           W+  T  F+ L +AA++DE+I C HGGLSPD+++++QIR I R  ++P  G  CDL+WSD
Sbjct: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207

Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
           P+ DV  W  + RG  + FGA V ++F++ ++L LICRAHQ+V +GY+F    +LVT++S
Sbjct: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267

Query: 236 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 280
           APNYC    N           + S  + K    +    +  +     V PPRT  P
Sbjct: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323


>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
           [Homo sapiens]
          Length = 327

 Score =  224 bits (570), Expect = 9e-59
 Identities = 115/296 (38%), Positives = 168/296 (56%), Gaps = 35/296 (11%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           + E +++ LC    ++ L +  +  +  P+ +CGDIHGQ                     
Sbjct: 29  MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLF 88

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRG  SLET   LLA K K+P+   LLRGNHE   I ++YGFYDEC+ ++ N   
Sbjct: 89  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKL 147

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           W+  T  F+ L +AA++DE+I C HGGLSPD+++++QIR I R  ++P  G  CDL+WSD
Sbjct: 148 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSD 207

Query: 177 PE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWS 235
           P+ DV  W  + RG  + FGA V ++F++ ++L LICRAHQ+V +GY+F    +LVT++S
Sbjct: 208 PDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 267

Query: 236 APNYCYRCGN-----------IASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTP 280
           APNYC    N           + S  + K    +    +  +     V PPRT  P
Sbjct: 268 APNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323


>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
           2 [Homo sapiens]
          Length = 286

 Score =  212 bits (539), Expect = 3e-55
 Identities = 104/222 (46%), Positives = 142/222 (63%), Gaps = 24/222 (10%)

Query: 52  GDIHGQ----------------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLR 89
           GDIHGQ                      GD+VDRG  SLET   LLA K K+P+   LLR
Sbjct: 19  GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78

Query: 90  GNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIK 149
           GNHE   I ++YGFYDEC+ +Y N   W+  T  F+ L +AA++DE+I C HGGLSPD++
Sbjct: 79  GNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 137

Query: 150 TLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAISPRGAGWLFGAKVTNEFVHINNL 208
           +++QIR I R  ++P +G  CDL+WSDP+ DV  W  + RG  + FGA+V  +F+H ++L
Sbjct: 138 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDL 197

Query: 209 KLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIM 250
            LICRAHQ+V +GY+F    +LVT++SAPNYC    N  ++M
Sbjct: 198 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMM 239


>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 384

 Score =  196 bits (498), Expect = 2e-50
 Identities = 103/229 (44%), Positives = 134/229 (58%), Gaps = 33/229 (14%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78
           L    +K LC    ++L EESN Q V  PVTV GD HGQGD++DRGYYS+E    LLA+K
Sbjct: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 231

Query: 79  AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138
             + + +T+L  NHESRQITQVY  Y+EC  K+GNAN                  D Q+ 
Sbjct: 232 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 274

Query: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198
           C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SDP+D DT                
Sbjct: 275 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 318

Query: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIA 247
              F H + L+L+ RAHQLV  G+ +  D  +V ++S PNYCY CG +A
Sbjct: 319 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCGGMA 367


>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  194 bits (493), Expect = 7e-50
 Identities = 102/226 (45%), Positives = 132/226 (58%), Gaps = 33/226 (14%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78
           L    +K LC    ++L EESN Q V  PVTV GD HGQGD++DRGYYS+E    LLA+K
Sbjct: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 110

Query: 79  AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138
             + + +T+L  NHESRQITQVY  Y+EC  K+GNAN                  D Q+ 
Sbjct: 111 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 153

Query: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198
           C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SDP+D DT                
Sbjct: 154 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 197

Query: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 244
              F H + L+L+ RAHQLV  G+ +  D  +V ++S PNYCY CG
Sbjct: 198 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243


>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  194 bits (493), Expect = 7e-50
 Identities = 102/226 (45%), Positives = 132/226 (58%), Gaps = 33/226 (14%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78
           L    +K LC    ++L EESN Q V  PVTV GD HGQGD++DRGYYS+E    LLA+K
Sbjct: 51  LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 110

Query: 79  AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138
             + + +T+L  NHESRQITQVY  Y+EC  K+GNAN                  D Q+ 
Sbjct: 111 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 153

Query: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198
           C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SDP+D DT                
Sbjct: 154 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 197

Query: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 244
              F H + L+L+ RAHQLV  G+ +  D  +V ++S PNYCY CG
Sbjct: 198 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCG 243


>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 2 [Homo sapiens]
          Length = 511

 Score =  179 bits (453), Expect = 3e-45
 Identities = 106/285 (37%), Positives = 149/285 (52%), Gaps = 38/285 (13%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           L E+   R+      +L +E N+  +  PVTVCGDIHGQ                     
Sbjct: 56  LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRGY+S+E   YL ALK  +P  + LLRGNHE R +T+ + F  EC+ KY     
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           +  C   FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P  G  CD++WSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234

Query: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228
           P ED             + RG  + +      EF+  NNL  I RAH+    GY+     
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294

Query: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
           +      L+T++SAPNY     N A+++ +++ N    + F   P
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 338


>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
           isoform 1 [Homo sapiens]
          Length = 521

 Score =  179 bits (453), Expect = 3e-45
 Identities = 106/285 (37%), Positives = 149/285 (52%), Gaps = 38/285 (13%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           L E+   R+      +L +E N+  +  PVTVCGDIHGQ                     
Sbjct: 56  LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRGY+S+E   YL ALK  +P  + LLRGNHE R +T+ + F  EC+ KY     
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           +  C   FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P  G  CD++WSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234

Query: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228
           P ED             + RG  + +      EF+  NNL  I RAH+    GY+     
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294

Query: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
           +      L+T++SAPNY     N A+++ +++ N    + F   P
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 338


>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 3 [Homo sapiens]
          Length = 469

 Score =  176 bits (446), Expect = 2e-44
 Identities = 104/274 (37%), Positives = 143/274 (52%), Gaps = 37/274 (13%)

Query: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--------------------- 57
           L E+   R+      +L +E N+  +  PVTVCGDIHGQ                     
Sbjct: 56  LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115

Query: 58  -GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 116
            GD+VDRGY+S+E   YL ALK  +P  + LLRGNHE R +T+ + F  EC+ KY     
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RV 174

Query: 117 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 176
           +  C   FD L +AAL+++Q LCVHGGLSP+I TLD IR ++R +E P  G  CD++WSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234

Query: 177 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE 228
           P ED             + RG  + +      EF+  NNL  I RAH+    GY+     
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294

Query: 229 K------LVTVWSAPNYCYRCGNIASIMVFKDVN 256
           +      L+T++SAPNY     N  + M+   +N
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKVTEMLVNVLN 328


>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
          Length = 499

 Score =  175 bits (443), Expect = 5e-44
 Identities = 102/245 (41%), Positives = 137/245 (55%), Gaps = 26/245 (10%)

Query: 48  VTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKWPDR 84
           +TVCGD HGQ                       GDFVDRG +S+E    L   K  +PD 
Sbjct: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296

Query: 85  ITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGL 144
             LLRGNHE+  + Q+YGF  E + KY  A  +   ++VF+ L +A  I+ ++L +HGGL
Sbjct: 297 FHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355

Query: 145 -SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV 203
            S D  TLD IR IERN++ P  G  CDL+WSDP+  +  +IS RG    FG  VT  F+
Sbjct: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFL 415

Query: 204 HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKL 262
             NNL  I R+H++  EGY+     + VTV+SAPNYC + GN AS +  +  + R +   
Sbjct: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQ 475

Query: 263 FRAVP 267
           F AVP
Sbjct: 476 FTAVP 480


>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
           c [Homo sapiens]
          Length = 515

 Score =  174 bits (442), Expect = 6e-44
 Identities = 102/270 (37%), Positives = 142/270 (52%), Gaps = 38/270 (14%)

Query: 34  LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71
           +L  E  +  V  P+TVCGDIHGQ                      GD+VDRGY+S+E  
Sbjct: 80  ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139

Query: 72  TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131
            YL  LK  +P  + LLRGNHE R +T+ + F  EC+ KY     +  C + FD L +AA
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RVYEACMEAFDSLPLAA 198

Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185
           L+++Q LCVHGGLSP+I TLD IR ++R +E P  G  CDL+WSDP ED           
Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258

Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237
             + RG  + +      EF+  NNL  I RAH+    GY+     +      L+T++SAP
Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318

Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
           NY     N A+++ +++ N    + F   P
Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347


>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
           a [Homo sapiens]
          Length = 525

 Score =  174 bits (442), Expect = 6e-44
 Identities = 102/270 (37%), Positives = 142/270 (52%), Gaps = 38/270 (14%)

Query: 34  LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71
           +L  E  +  V  P+TVCGDIHGQ                      GD+VDRGY+S+E  
Sbjct: 80  ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139

Query: 72  TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131
            YL  LK  +P  + LLRGNHE R +T+ + F  EC+ KY     +  C + FD L +AA
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RVYEACMEAFDSLPLAA 198

Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185
           L+++Q LCVHGGLSP+I TLD IR ++R +E P  G  CDL+WSDP ED           
Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258

Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237
             + RG  + +      EF+  NNL  I RAH+    GY+     +      L+T++SAP
Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318

Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
           NY     N A+++ +++ N    + F   P
Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347


>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
           b [Homo sapiens]
          Length = 524

 Score =  174 bits (442), Expect = 6e-44
 Identities = 102/270 (37%), Positives = 142/270 (52%), Gaps = 38/270 (14%)

Query: 34  LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71
           +L  E  +  V  P+TVCGDIHGQ                      GD+VDRGY+S+E  
Sbjct: 80  ILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECV 139

Query: 72  TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131
            YL  LK  +P  + LLRGNHE R +T+ + F  EC+ KY     +  C + FD L +AA
Sbjct: 140 LYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSE-RVYEACMEAFDSLPLAA 198

Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185
           L+++Q LCVHGGLSP+I TLD IR ++R +E P  G  CDL+WSDP ED           
Sbjct: 199 LLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFS 258

Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237
             + RG  + +      EF+  NNL  I RAH+    GY+     +      L+T++SAP
Sbjct: 259 HNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAP 318

Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
           NY     N A+++ +++ N    + F   P
Sbjct: 319 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 347


>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
           sapiens]
          Length = 512

 Score =  170 bits (430), Expect = 1e-42
 Identities = 100/270 (37%), Positives = 141/270 (52%), Gaps = 38/270 (14%)

Query: 34  LLLEESNVQPVSTPVTVCGDIHGQ----------------------GDFVDRGYYSLETF 71
           +L +E  +  V  P+TVCGDIHGQ                      GD+VDRGY+S+E  
Sbjct: 67  ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126

Query: 72  TYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAA 131
            YL +LK   P  + LLRGNHE R +T  + F  EC+ KY     +  C + FD L +AA
Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSE-QVYDACMETFDCLPLAA 185

Query: 132 LIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP-EDVDTWAI----- 185
           L+++Q LCVHGG+SP+I +LD IR ++R  E P  G  CDL+WSDP ED           
Sbjct: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245

Query: 186 --SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK------LVTVWSAP 237
             + RG  + +      EF+  NNL  I RAH+    GY+     +      L+T++SAP
Sbjct: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305

Query: 238 NYCYRCGNIASIMVFKDVNTREPKLFRAVP 267
           NY     N A+++ +++ N    + F   P
Sbjct: 306 NYLDVYNNKAAVLKYEN-NVMNIRQFNCSP 334


>gi|23312374 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1b [Homo sapiens]
          Length = 625

 Score =  104 bits (260), Expect = 8e-23
 Identities = 72/237 (30%), Positives = 111/237 (46%), Gaps = 43/237 (18%)

Query: 45  STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81
           S  VT+CGD+HG+                       GDFVDRG  S+E    L      +
Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223

Query: 82  PDRITLLRGNHESRQITQVYGFYDECQTKYG--NANAWRYCTKVFDMLTVAALIDEQILC 139
           P+ + L RGNHE   +   YGF  E   KY        +   + +  L +  ++D +IL 
Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283

Query: 140 VHGGLSPDIKTLDQIRTIERNQE----IP------------HKGAFCDLVWSDPEDVD-T 182
           +HGG+S +   L+ +  +ERN+     IP                  D++WSDP   +  
Sbjct: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGC 342

Query: 183 WAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNY 239
           +  + RG G  FG  VT++ ++   LK++ R+H+   EGY+   D K+VT++SA NY
Sbjct: 343 FPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 399


>gi|23312380 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1 [Homo sapiens]
          Length = 653

 Score = 94.7 bits (234), Expect = 8e-20
 Identities = 72/265 (27%), Positives = 112/265 (42%), Gaps = 71/265 (26%)

Query: 45  STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81
           S  VT+CGD+HG+                       GDFVDRG  S+E    L      +
Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223

Query: 82  PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 139
           P+ + L RGNHE   +   YGF  E   KY        +   + +  L +  ++D +IL 
Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283

Query: 140 VHGGLSPDIKTLDQIRTIERNQ--------------------------------EIPHKG 167
           +HGG+S +   L+ +  +ERN+                                 I   G
Sbjct: 284 IHGGIS-ETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNG 342

Query: 168 A------------FCDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 214
           +              D++WSDP   +  +  + RG G  FG  VT++ ++   LK++ R+
Sbjct: 343 SPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRS 402

Query: 215 HQLVHEGYKFMFDEKLVTVWSAPNY 239
           H+   EGY+   D K+VT++SA NY
Sbjct: 403 HECKPEGYEICHDGKVVTIFSASNY 427


>gi|23312386 serine/threonine protein phosphatase with EF-hand
           motifs 2 [Homo sapiens]
          Length = 753

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 61/168 (36%), Positives = 77/168 (45%), Gaps = 37/168 (22%)

Query: 30  YVCDLLLEES-------NVQPVST----PVTVCGDIHGQ--------------------- 57
           YV +LL E         N+  VST     +TVCGD+HGQ                     
Sbjct: 145 YVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYV 204

Query: 58  --GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKY--GN 113
             GDFVDRG  S+E    L A    +P    L RGNHE   +   YGF  E   KY    
Sbjct: 205 FNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHG 264

Query: 114 ANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQ 161
               R    VF  L +A LIDE++L +HGG+S DI  L+ +  IER++
Sbjct: 265 KEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSK 311



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 2/76 (2%)

Query: 171 DLVWSDPEDVDTW-AISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEK 229
           D++WSDP   +   A + RG G  FG  VT + +   N++ + R+H+   EGY+F  + K
Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502

Query: 230 LVTVWSAPNYCYRCGN 245
           ++T++SA NY Y  G+
Sbjct: 503 VLTIFSASNY-YEVGS 517


>gi|23312378 protein phosphatase with EF hand calcium-binding domain
           1 isoform 3 [Homo sapiens]
          Length = 591

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 26/142 (18%)

Query: 45  STPVTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKW 81
           S  VT+CGD+HG+                       GDFVDRG  S+E    L      +
Sbjct: 164 SKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVY 223

Query: 82  PDRITLLRGNHESRQITQVYGFYDECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILC 139
           P+ + L RGNHE   +   YGF  E   KY        +   + +  L +  ++D +IL 
Sbjct: 224 PNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILV 283

Query: 140 VHGGLSPDIKTLDQIRTIERNQ 161
           +HGG+S +   L+ +  +ERN+
Sbjct: 284 IHGGIS-ETTDLNLLHRVERNK 304


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 18/67 (26%), Positives = 28/67 (41%)

Query: 138 LCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAK 197
           + V   LS  I      R IE N+    +GA   + W+ PE ++    + +   W FG  
Sbjct: 370 ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429

Query: 198 VTNEFVH 204
           +T    H
Sbjct: 430 LTEIVTH 436


>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 18/67 (26%), Positives = 28/67 (41%)

Query: 138 LCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAK 197
           + V   LS  I      R IE N+    +GA   + W+ PE ++    + +   W FG  
Sbjct: 370 ILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429

Query: 198 VTNEFVH 204
           +T    H
Sbjct: 430 LTEIVTH 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,715,934
Number of Sequences: 37866
Number of extensions: 516757
Number of successful extensions: 979
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 37
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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